date is 2020-11
Select an archive month  
July 2025
June 2025
May 2025
April 2025
March 2025
February 2025
January 2025
December 2024
November 2024
October 2024
September 2024
August 2024
July 2024
June 2024
May 2024
April 2024
March 2024
February 2024
January 2024
December 2023
November 2023
October 2023
September 2023
August 2023
July 2023
June 2023
May 2023
April 2023
March 2023
February 2023
January 2023
December 2022
November 2022
October 2022
September 2022
August 2022
July 2022
June 2022
May 2022
April 2022
March 2022
February 2022
January 2022
December 2021
November 2021
October 2021
September 2021
August 2021
July 2021
June 2021
May 2021
April 2021
March 2021
February 2021
January 2021
December 2020
November 2020
October 2020
September 2020
August 2020
July 2020
June 2020
May 2020
April 2020
March 2020
February 2020
January 2020
December 2019
November 2019
October 2019
September 2019
August 2019
July 2019
June 2019
May 2019
April 2019
March 2019
February 2019
January 2019
December 2018
November 2018
October 2018
September 2018
August 2018
July 2018
June 2018
May 2018
April 2018
March 2018
February 2018
January 2018
December 2017
November 2017
October 2017
September 2017
August 2017
July 2017
June 2017
May 2017
April 2017
March 2017
February 2017
January 2017
December 2016
November 2016
October 2016
September 2016
August 2016
July 2016
June 2016
May 2016
April 2016
March 2016
February 2016
January 2016
December 2015
November 2015
October 2015
September 2015
August 2015
July 2015
June 2015
May 2015
April 2015
March 2015
February 2015
January 2015
December 2014
November 2014
October 2014
September 2014
August 2014
July 2014
June 2014
May 2014
April 2014
March 2014
February 2014
January 2014
December 2013
November 2013

Archive, 2020-11

4 Analytical validation and performance characteristics of a 48-gene next-generation sequencing panel for detecting potentially actionable genomic alterations in myeloid neoplasms
Rosenthal, S. H.; Gerasimova, A.; Ma, C.; Li, H.-R.; Grupe, A.; Chong, H.; Acab, A.; Smolgovsky, A.; Owen, R.; Elzinga, C.; Chen, R.; Sugganth, D.; Freitas, T.; Graham, J.; Champion, K.; Bhattacharya, A.; Racke, F.; Lacbawan, F.
10.1101/2020.11.30.403634 — cancer biology — Posted on 2020-11-30
5 Genomic surveillance of antimicrobial resistance shows cattle are a moderate source of multi-drug resistant non-typhoidal Salmonella in Mexico
Delgado-Suarez, E. J.; Palos-Guiterrez, T.; Ruiz-Lopez, F. A.; Hernandez Perez, C. F.; Ballesteros-Nova, N. E.; Soberanis-Ramos, O.; Mendez-Medina, R. D.; Allard, M. W.; Rubio-Lozano, M. S.
10.1101/2020.11.30.403618 — genomics — Posted on 2020-11-30
8 Characterization of genetic diversity and population structure within Staphylococcus chromogenes by multilocus sequence Typing
Huebner, R.; Mugabi, R.; Hetesy, G.; Fox, L.; De Vliegher, S.; De Visscher, A.; Barlow, J. W.; Sensabaugh, G.
10.1101/2020.11.30.403683 — microbiology — Posted on 2020-11-30
13 An Optimized CRISPR/Cas9 Approach for Precise Genome Editing in Neurons
FANG, H. L.; Bygrave, A. M.; Roth, R. H.; Johnson, R. C.; Huganir, R. L.
10.1101/2020.11.30.402883 — neuroscience — Posted on 2020-11-30
15 Topical heterogeneity in affective touch: Does it impact body image?
Cazzato, V.; Sacchetti, S.; Shin, S.; Makdani, A.; Trotter, P. D.; McGlone, F.
10.1101/2020.11.30.403600 — neuroscience — Posted on 2020-11-30
18 Empty sella syndrome as a window into the neuroprotective effects of prolactin
Paul, D. A.; Strawderman, E.; Rodriguez, A.; Hoang, R.; Schneider, C.; Haber, S.; Chernoff, B. L.; Shafiq, I.; Williams, Z. R.; Vates, G. E.; Mahon, B. Z.
10.1101/2020.11.30.403576 — neuroscience — Posted on 2020-11-30
19 Creation of an Open Science Dataset from PREVENT-AD, a Longitudinal Cohort Study of Pre-symptomatic Alzheimer's Disease.
Tremblay-Mercier, J.; Madjar, C.; Das, S.; Pichet-Binette, A.; Dyke, S. O. M.; Etienne, P.; Lafaille-Magnan, M.-E.; Remz, J.; Bellec, P.; Collins, D. L.; Rajah, M. N.; Bohbot, V. D.; Leoutsakos, J.-M.; Iturria-Medina, Y.; Kat, J.; Hoge, R. D.; Gauthier, S.; Tardif, C.; Chakravarty, M. M.; Poline, J.-B.; Rosa-Neto, P.; Evans, A. C.; Villeneuve, S.; Poirier, J.; Breitner, J. C. S.; the PREVENT-AD Research Group,
10.1101/2020.03.04.976670 — neuroscience — Posted on 2020-11-30
21 Bacteriological and histopathological findings in cetaceansthat stranded in the Philippines from 2017 to 2018
Obusan, M. C.; Caras, J. A. C.; Lumang, L. S. L.; Calderon, E. J. S.; Villanueva, R. M. D.; Salibay, C. C.; Siringan, M. A. T.; Rivera, W. L.; Masangkay, J. S.; Aragones, L. V.
10.1101/2020.11.30.403568 — zoology — Posted on 2020-11-30
26 Multiple binding sites for resin-acid derivatives on the voltage-sensor domain of the Shaker potassium channel
Silvera Ejneby, M.; Gromova, A.; Ottosson, N. E.; Borg, S.; Estrada-Mondragon, A.; Yazdi, S.; Apostolakis, P.; Elinder, F.; Delemotte, L.
10.1101/2020.06.11.146548 — biophysics — Posted on 2020-11-30
29 Association between the extent of DNA methylation at the CpG sites of HIF3A and parameters of obesity in the general Japanese population
Mizuno, G.; Yamada, H.; Munetsuna, E.; Yamazaki, M.; Ando, Y.; Fujii, R.; Tsuboi, Y.; Teshigawara, A.; Kageyama, I.; Osakabe, K.; Sugimoto, K.; Ishikawa, H.; Ichino, N.; Ohta, Y.; Ohashi, K.; Hashimoto, S.; Suzuki, K.; Koji Suzuki,
10.1101/2020.11.30.403709 — biochemistry — Posted on 2020-11-30
34 No change in oxytocin level before a human intergroup competition: study among Polish players before rugby and handball matches
Koziel, S.; Kociuba, M.; Ignasiak, Z.; Rokita, A.; Cichy, I.; Dutkowski, A.; Scislak, M.; Kochan, K.; Sebastjan, A.; Spinek, A.; Lorek, D.; Chakraborty, R.; Bogin, B.
10.1101/2020.11.30.403592 — evolutionary biology — Posted on 2020-11-30
36 BUB-1 targets PP2A:B56 to regulates chromosome congression during meiosis I in C. elegans oocytes
Bel Borja, L.; Soubigou, F.; Taylor, S. J. P.; Fraguas Bringas, C.; Budrewicz, J.; Lara-Gonzalez, P.; Sorensen Turpin, C. G.; Bembenek, J. N.; Cheerambathur, D. K.; Pelisch, F.
10.1101/2020.06.12.148254 — cell biology — Posted on 2020-11-30
37 The first AI-based mobile application for antibiotic resistance testing
Pascucci, M.; Royer, G.; Adamek, J.; Aristizabal, D.; Bezzarga, A.; Blanche, L.; Boniface-Chang, G.; Brunner, A.; Curel, C.; Dulac-Arnold, G.; Malou, N.; Nordon, C.; Runge, V.; Samson, F.; Sebastian, E.; Soukieh, D.; Vert, J.-P.; Ambroise, C.; Madoui, M.-A.
10.1101/2020.07.23.216929 — microbiology — Posted on 2020-11-30
40 Ethanol's action at BK channels accelerates the transition from moderate to excessive alcohol consumption
Okhuarobo, A.; Kreifeldt, M.; Bhattacharyya, P.; Dopico, A. M.; Roberts, A. J.; Homanics, G. E.; Contet, C.
10.1101/2020.10.29.360107 — neuroscience — Posted on 2020-11-30
43 Rapid Cortical Adaptation and the Role of Thalamic Synchrony During Wakefulness
Wright, N. C.; Borden, P. Y.; Liew, Y. J.; Bolus, M. F.; Stoy, W. M.; Forest, C. R.; Stanley, G. B.
10.1101/2020.10.08.331660 — neuroscience — Posted on 2020-11-30
44 Anatomy and activity patterns in a multifunctional motor neuron and its surrounding circuits
Ashaber, M.; Tomina, Y.; Kassraian-Fard, P.; Bushong, E. A.; Kristan, W. B.; Ellisman, M. H.; Wagenaar, D. A.
10.1101/2020.03.09.984013 — neuroscience — Posted on 2020-11-30
51 Membrane Env liposomes for immunization with HIV spikes
Leaman, D. P.; Stano, A.; Chen, Y.; Zhang, L.; Zwick, M. B.
10.1101/2020.11.29.403204 — immunology — Posted on 2020-11-30
52 A Neutralizing Antibody-Conjugated Photothermal Nanoparticle Captures and Inactivates SARS-CoV-2
Cai, X.; Prominski, A.; Lin, Y.; Ankenbruck, N.; Rosenberg, J.; Chen, M.; Shi, J.; Chang, E. B.; Penaloza-MacMaster, P.; Tian, B.; Huang, J.
10.1101/2020.11.30.404624 — bioengineering — Posted on 2020-11-30
53 Characterization of SARS-CoV-2 N protein reveals multiple functional consequences of the C-terminal domain
Wu, C.; Qavi, A. J.; Hachim, A.; Kavian, N.; Cole, A. R.; Moyle, A. B.; Wagner, N. D.; Sweeney-Gibbons, J.; Rohrs, H. W.; Gross, M. L.; Peiris, J. S. M.; Basler, C. F.; Farnsworth, C. W.; Valkenburg, S. A.; Amarasinghe, G. K.; Leung, D. W.
10.1101/2020.11.30.404905 — biochemistry — Posted on 2020-11-30
55 The Erythropoietin Receptor Stimulates Rapid Cycling and Formation of Larger Red Cells During Mouse and Human Erythropoiesis
Hidalgo, D.; Bejder, J.; Pop, R.; Gellatly, K.; Scalf, S. M.; Eastman, A. E.; Chen, J.-J.; Zhu, J. L.; Heuberger, J. A. A. C.; Guo, S.; Koury, M. J.; Nordsborg, N. B.; Socolovsky, M.
10.1101/2020.11.30.404780 — developmental biology — Posted on 2020-11-30
56 Deletion of INPP5E in the murine retina impairs axoneme formation and prevents photoreceptor disc morphogenesis
Sharif, A.; Gerstner, C. D.; Cady, M. A.; Arshavsky, V. Y.; Mitchell, C. A.; Ying, G.; Frederick, J. M.; Baehr, W.
10.1101/2020.11.29.403030 — neuroscience — Posted on 2020-11-30
58 Understanding the Evolutionary Games in NSCLC Microenvironment
Bhattacharya, R.; Velde, R. V.; Marusyk, V.; Desai, B.; Kaznatcheev, A.; Marusyk, A.; Basanta, D.
10.1101/2020.11.30.404350 — cancer biology — Posted on 2020-11-30
61 The interactome of the N-terminus of band 3 regulates red blood cell metabolism and storage quality
Issaian, A.; Hay, A.; Dzieciatkowska, M.; Roberti, D.; Perrotta, S.; Darula, Z.; Redzic, J. S.; Busch, M. P.; Page, G. P.; Hansen, K.; Eisenmesser, E. Z.; Zimring, J. C.; D'Alessandro, A.
10.1101/2020.11.30.404756 — biochemistry — Posted on 2020-11-30
63 H3K4 trimethylation is required for postnatal pancreatic endocrine cell functional maturation
Campbell, S. A.; Begin, J.; McDonald, C. L.; Vanderkruk, B.; Stephan, T. L.; Hoffman, B. G.
10.1101/2020.11.29.402990 — developmental biology — Posted on 2020-11-30
64 p38-MAPK mediated rRNA processing and translation regulation enables PrE differentiation during mouse blastocyst maturation.
Bora, P.; Gahurova, L.; Masek, T.; Hauserova, A.; Potesil, D.; Jansova, D.; Susor, A.; Zdrahal, Z.; Ajduk, A.; Pospisek, M.; Bruce, A. W.
10.1101/2020.11.30.403931 — developmental biology — Posted on 2020-11-30
68 Consequences of human cytomegalovirus infection on small extracellular vesicles isolated from first trimester placental histocultures
Bergamelli, M.; Martin, H.; Benard, M.; Ausseil, J.; Mansuy, J.-M.; Hurbain, I.; Mouysset, M.; Groussolles, M.; Cartron, G.; Tanguy le Gac, Y.; Moinard, N.; Suberbielle, E.; Izopet, J.; Tscherning, C.; Raposo, G.; Gonzalez-Dunia, D.; d'Angelo, G.; Malnou, C. E.
10.1101/2020.11.30.402693 — cell biology — Posted on 2020-11-30
69 Remodeling and activation mechanisms of outer arm dynein revealed by cryo-electron microscopy
Kubo, S.; Yang, S. K.; Black, C.; Dai, D.; Valente, M.; Gaertig, J.; Ichikawa, M.; Bui, K. H.
10.1101/2020.11.30.404319 — cell biology — Posted on 2020-11-30
71 Loss of a subunit of vacuolar ATPase identifies unexpected biological signatures of reduced organelle acidification in vivo
Pottie, L.; Van Gool, W.; Vanhooydonck, M.; Hanisch, F.-G.; Goeminne, G.; Rajkovic, A.; Coucke, P.; Sips, P.; Callewaert, B.
10.1101/2020.11.30.397463 — molecular biology — Posted on 2020-11-30
74 Immunofocusing and enhancing autologous Tier-2 HIV-1 neutralization by displaying Env trimers on two-component protein nanoparticles
Brouwer, P. J. M.; Antanasijevic, A.; de Gast, M.; Allen, J. D.; Allen, J. D.; Bijl, T. P. L.; Yasmeen, A.; Ravichandran, R.; Burger, J.; Ozorowski, G.; Torres, J. L.; LaBranche, C.; Montefiori, D.; Ringe, R. P.; van Gils, M.; Moore, J. P.; Klasse, P. J.; Crispin, M.; King, N. P.; Ward, A.; Sanders, R. W.
10.1101/2020.11.30.403543 — microbiology — Posted on 2020-11-30
75 Emetine as an antiviral agent suppresses SARS-CoV-2 replication by inhibiting interaction of viral mRNA with eIF4E: An in vitro study
Kumar, R.; Khandelwal, N.; Chander, Y.; Riyesh, T.; Gulati, B. R.; Pal, Y.; Tripathi, B. N.; Barua, S.; Kumar, N.
10.1101/2020.11.29.401984 — microbiology — Posted on 2020-11-30
81 A Novel SARS-CoV-2 Multitope Protein/Peptide Vaccine Candidate is Highly Immunogenic and Prevents Lung Infection in an Adeno Associated Virus Human Angiotensin-Converting Enzyme 2 (AAV hACE2) Mouse Model
Guirakhoo, F.; Kuo, L.; Peng, J.; Huang, J. H.; Kuo, B.; Lin, F.; Liu, K.; Liu, Z.; Wu, G.; Ding, S.; Hou, L.-L.; Cheng, J.; Yang, V.; Jiang, H.; Wang, J.; Chen, T.; Xia, W.; Lin, E.; Hung, C. H.; Chen, K.; Shih, Z.; Lin, Y.; Schurter, B. T.; Hu, M. M.; Heppner, G.; Malherbe, D. C.; Bukreyev, A.; Hellerstein, M.; Monath, T.; Wang, C. Y.
10.1101/2020.11.30.399154 — immunology — Posted on 2020-11-30
84 Gating mechanism of cardiac ryanodine receptor 2 upon calcium ion binding
Ogawa, H.; Murayama, T.; Kobayashi, T.; Kurebayashi, N.; Saito, K.; Sakurai, T.; Kodama, M.; Tsutsumi, A.; Kikkawa, M.
10.1101/2020.11.30.401026 — biochemistry — Posted on 2020-11-30
86 The kinesin KIF1C transports APC-dependent mRNAs to cell protrusions
Pichon, X.; Moissoglu, K.; Coleno, E.; Wang, T.; Imbert, A.; Peter, M.; Chouaib, R.; Walter, T.; Mueller, F.; Zibara, K.; Bertrand, E.; Mili, S.
10.1101/2020.11.30.403394 — cell biology — Posted on 2020-11-30
87 Recombinant Fc-fusion vaccine of RBD induced protection against SARS-CoV-2 in non-human primate and mice
Sun, Y.; Han, G.; Wei, W.; Hu, Z.; Sun, S.; He, L.; Zhao, Z.; Gu, H.; Wang, T.; Yang, X.; Chen, S.; Deng, Y.; Li, J.; Zhao, J.; Li, L.; Li, X.; He, P.; Li, G.; Li, H.; Gao, C.; Lang, X.; Geng, S.; Wang, X.; Fei, G.; Li, Y.; Gao, Y.; Fang, X.; Zhao, Y.
10.1101/2020.11.29.402339 — immunology — Posted on 2020-11-30
88 The tumor suppressor protein PTEN undergoes amyloid-like aggregation in tumor cells.
Claes, F.; Maritschnegg, E.; De Baets, G.; Siekierska, A.; Saiz Rubio, M.; Ramakers, M.; Michiels, E.; De Smet, F.; Depreeuw, J.; Vergote, I.; Vanderstichele, A.; van den Broeck, A.; Olbrecht, S.; Hermans, E.; Amant, F.; Lambrechts, D.; Nilsson, P. R.; Rousseau, F.; Schymkowitz, J.
10.1101/2020.11.30.402115 — cancer biology — Posted on 2020-11-30
89 First computational design of Covid-19 coronavirus vaccine using lambda superstrings
Martinez, L.; Malaina, I.; Salcines, D.; Teran, H.; Alegre, S.; MartInez de la Fuente, I.; Gonzalez, E.; Ocejo, G.; Alvarez, C.
10.1101/2020.11.30.403824 — bioinformatics — Posted on 2020-11-30
90 Isolation, spectral characterization and biological activity of fractions of the flavonoid-containing Gratiola officinalis L. extract
Shirokov, A.; Grinev, V.; Polukonova, N.; Verkhovsky, R.; Doroshenko, A.; Mudrak, D.; Navolokin, N.; Polukonova, A.; Bucharskaya, A.; Maslyakova, G.
10.1101/2020.11.30.404475 — biochemistry — Posted on 2020-11-30
92 Uncovering an allosteric mode of action for a selective inhibitor of human Bloom syndrome protein
Chen, X.; Ali, Y.; Fisher, C. E. L.; Arribas-Bosacoma, R.; Rajasekaran, M. B.; Williams, G.; Walker, S.; Roe, S. M.; Pearl, L. H.; Ward, S. E.; Pearl, F. M. G.; Oliver, A. W.
10.1101/2020.11.30.403493 — biochemistry — Posted on 2020-11-30
94 Computational prediction of protein subdomain stability in MYBPC3 enables clinical risk stratification in hypertrophic cardiomyopathy and enhances variant interpretation.
Thompson, A. D.; Helms, A. S.; Kannan, A.; Job, J.; Lakdawala, N. K.; Wittekind, S. G.; Pereira, A.; Jacoby, D. L.; Colan, S. D.; Ashley, E. A.; Saberi, S.; Ware, J. S.; Ingles, J.; Semsarian, C.; Michels, M.; Mazzarotto, F.; Olivotto, I.; Ho, C. Y.; Day, S. M.
10.1101/2020.11.29.402974 — genetics — Posted on 2020-11-30
95 Hypothalamic glucocorticoid receptor in CRF neurons is essential for HPA axis habituation to repeated stressor
Dournes, C.; Dine, J.; Lopez, J.-P.; Brivio, E.; Anderzhanova, E.; Roeh, S.; Kuehne, C.; Holzapfel, M.; Huettl, R.-E.; Stoffel, R.; Tietze, L.; Eggert, C.; Schieven, M.; Jakovcevski, M.; Deussing, J. M.; Chen, A.
10.1101/2020.11.30.402024 — neuroscience — Posted on 2020-11-30
98 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-30
101 Oligodendrocytes support axonal transport and maintenance via exosome secretion
Frühbeis, C.; Kuo-Elsner, W. P.; Mueller, C.; Barth, K.; Peris, L.; Tenzer, S.; Möbius, W.; Werner, H.; Nave, K.-A.; Fröhlich, D.; Krämer-Albers, E.-M.
10.1101/2019.12.20.884171 — neuroscience — Posted on 2020-11-30
103 Sex Differences in MRI-Based Metrics of Glioma Invasion and Brain Mechanics
Anderies, B. J.; Yee, S. F.; Jackson, P. R.; Rickertsen, C. R.; Hawkins-Daarud, A. J.; Johnston, S. K.; Clark-Swanson, K. R.; Hoxworth, J. M.; Le, Y.; Zhou, Y.; Pepin, K. M.; Massey, S. C.; Hu, L. S.; Huston, J. R.; Swanson, K. R.
10.1101/2020.11.21.352724 — biophysics — Posted on 2020-11-30
105 Cell Layers: Uncovering clustering structure and knowledge in unsupervised single-cell transcriptomic analysis
Blair, A.; Hu, R. K.; Farah, E. N.; Pollard, K. S.; Przytycki, P. F.; Kathiriya, I. S.; Bruneau, B. G.
10.1101/2020.11.29.400614 — bioinformatics — Posted on 2020-11-30
110 Evolutionary drivers of polymorphic sexual signals in slender anoles
Prates, I.; D'Angiolella, A. B.; Rodrigues, M. T.; Melo-Sampaio, P. R.; de Queiroz, K.; Bell, R. C.
10.1101/2020.11.29.402784 — evolutionary biology — Posted on 2020-11-30
112 DNA methylation study of age and sex in baboons and four other primates
Horvath, S.; Haghani, A.; Zoller, J. A.; Ernst, J.; Pellegrini, M.; Jasinska, A. J.; Mattison, J. A.; Raj, K.; Salmon, A. B.; Jenkins, S.; Li, C.; Nathanielsz, P. W.
10.1101/2020.11.29.402891 — developmental biology — Posted on 2020-11-30
119 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-30
120 Apoptosis, G1 phase stall and premature differentiation account for low chimeric competence of Human and rhesus monkey naive pluripotent stem cells
Aksoy, I.; Rognard, C.; Moulin, A.; Marcy, G.; Masfaraud, E.; Wianny, F.; Cortay, V.; Bellemin-Menard, A.; Doerflinger, N.; Dirheimer, M.; Mayere, C.; Lynch, C.; Raineteau, O.; Joly, T.; Dehay, C.; Serrano, M.; Afanassieff, M.; Savatier, P.
10.1101/2020.03.27.011890 — cell biology — Posted on 2020-11-30
122 Accelerated Predictive Healthcare Analytics with Pumas, A High Performance Pharmaceutical Modeling and Simulation Platform
Rackauckas, C. V.; Ma, Y.; Noack, A.; Dixit, V.; Mogensen, P.; Byrne, S.; Maddhashiya, S.; Calderon, J. B. S.; Nyberg, J.; Gobburu, J.; Ivaturi, V.
10.1101/2020.11.28.402297 — pharmacology and toxicology — Posted on 2020-11-30
123 Epithelial colonies in vitro elongate through collective effects
Comelles, J.; Soumya, S. S.; Lu, L.; Le-Maout, E.; Anvitha, S.; Salbreux, G.; Jülicher, F.; Inamdar, M. M.; Riveline, D.
10.1101/755181 — biophysics — Posted on 2020-11-30
125 FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs
Griffith, B. G. C.; Upstill-Goddard, R.; Brunton, H.; Grimes, G. R.; Biankin, A. V.; Serrels, B.; Byron, A.; Frame, M. C.
10.1101/2020.07.15.177212 — genomics — Posted on 2020-11-30
126 Rapid molecular evolution of Spiroplasma symbionts of Drosophila
Gerth, M.; Martinez Montoya, H.; Ramirez, P.; Masson, F.; Griffin, J. S.; Aramayo, R.; Siozios, S.; Lemaitre, B.; Mateos, M.; Hurst, G. D.
10.1101/2020.06.23.165548 — evolutionary biology — Posted on 2020-11-30
129 Global architecture of the nucleus in single cells by DNA seqFISH+ and multiplexed immunofluorescence
Takei, Y.; Yun, J.; Ollikainen, N.; Zheng, S.; Pierson, N.; White, J.; Shah, S.; Thomassie, J.; Eng, C.-H. L.; Guttman, M.; Yuan, G.-C.; Cai, L.
10.1101/2020.11.29.403055 — systems biology — Posted on 2020-11-30
130 Mapping the Cellular Origin and Early Evolution of Leukemia in Down Syndrome
Wagenblast, E.; Araujo, J.; Gan, O. I.; Cutting, S. K.; Murison, A.; Krivdova, G.; Azkanaz, M.; McLeod, J. L.; Smith, S. A.; Marhon, S. A.; Gabra, M.; Chan-Seng-Yue, M.; Garcia-Prat, L.; Salmena, L.; De Carvalho, D. D. D.; Chong, K.; Roifman, M.; Shannon, P.; Wang, J. C. Y.; Hitzler, J. K.; Chitayat, D.; Dick, J. E.; Lechman, E. R.
10.1101/2020.11.29.402800 — cancer biology — Posted on 2020-11-30
132 Computational optical sectioning by phase-space imaging with an incoherent multiscale scattering model
Zhang, Y.; Lu, Z.; Wu, J.; Lin, X.; Jiang, D.; Cai, Y.; Xie, J.; Zhu, T.; Ji, X.; Dai, Q.
10.1101/2020.11.29.402958 — cell biology — Posted on 2020-11-30
133 Integrative Analysis of Phenomic, Genomic, and Transcriptomic to Identify Potential Functional Genes of Yaks in Plain and Plateau
Wang, J.; Guan, J.; Yixi, K.; Shu, T.; Chai, Z.; Wang, J.; Wang, H.; Wu, Z.; Cai, X.; Zhong, J.; Luo, X.
10.1101/2020.11.29.392167 — genomics — Posted on 2020-11-30
134 The molecular logic of synaptic wiring at the single cell level
Lohmann, I.; Velten, J.; Agarwal, R.; van Nierop y Sanchez, P.; Bognar, L.; Paulsen, M.; Velten, L.
10.1101/2020.11.30.402057 — developmental biology — Posted on 2020-11-30
135 Central Neural Regulation of Parathyroid Hormone
Zhang, L.; Liu, N.; Shao, J.; Gao, D.; Liu, Y.; Chen, D.; Wang, L.; Lu, W. W.; Yang, F.
10.1101/2020.11.30.403279 — neuroscience — Posted on 2020-11-30
138 Non-invasive surveys of mammalian viruses using environmental DNA
Alfano, N.; Dayaram, A.; Axtner, J.; Tsangaras, K.; Kampmann, M.-L.; Mohamed, A.; Wong, S. T.; Gilbert, M. T. P.; Wilting, A.; Greenwood, A. D.
10.1101/2020.03.26.009993 — molecular biology — Posted on 2020-11-30
142 Design of proteins presenting discontinuous functional sites using deep learning
Tischer, D.; Lisanza, S.; Wang, J.; Dong, R.; Anishchenko, I. K.; Milles, L.; Ovchinnikov, S.; Baker, D.
10.1101/2020.11.29.402743 — biochemistry — Posted on 2020-11-29
143 Identification of herboxidiene features that mediate conformation-dependent SF3B1 interactions to inhibit splicing.
Gamboa Lopez, A.; Allu, S. R.; Mendez, P.; Reddy, G. C.; Maul-Newby, H. M.; Ghosh, A. K.; Jurica, M. S.
10.1101/2020.11.18.387712 — molecular biology — Posted on 2020-11-29
146 Altered functional integration of brain activity is a marker of impaired cognitive performance following sleep deprivation
Cross, N.; Pomares, F. B.; Nguyen, A.; Perrault, A. A.; Jegou, A.; Uji, M.; Lee, K.; Razavipour, F.; Ali, O. B. K.; Aydin, U.; Benali, H.; Grova, C.; Dang-Vu, T. T.
10.1101/2020.11.28.402305 — neuroscience — Posted on 2020-11-29
148 Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis
Fujihara, K. M.; Zhang, B. Z.; Jackson, T. D.; Nijagal, B.; Ang, C.-S. M.; Nikolic, I.; Sutton, V.; Trapani, J.; Simpson, K. J.; Stojanovski, D.; Leimkuehler, S.; Haupt, S.; Phillips, W. A.; Clemons, N. J.
10.1101/2020.11.29.398867 — cancer biology — Posted on 2020-11-29
151 Bioelectrical Interfaces with Cortical Spheroids in Three-Dimensions
Kalmykov, A.; Reddy, J. W.; Bedoyan, E.; Wang, Y.; Garg, R.; Rastogi, S. K.; Cohen-Karni, D.; Chamanzar, M.; Cohen-Karni, T.
10.1101/2020.11.29.401638 — bioengineering — Posted on 2020-11-29
153 Microfluidic Device Facilitates Novel In Vitro Modeling of Human Neonatal Necrotizing Enterocolitis-on-a-Chip
Lanik, W. E.; Luke, C. J.; Nolan, L. S.; Gong, Q.; Rimer, J. M.; Gale, S. E.; Luc, R.; Bidani, S. S.; Sibald, C. A.; Lewis, A. N.; Mihi, B.; Agrawal, P.; Goree, M.; Maestas, M.; Hu, E.; Peters, D. G.; Good, M.
10.1101/2020.11.29.402735 — cell biology — Posted on 2020-11-29
154 The nature of mitotic forces in epithelial monolayers
Gupta, V. K.; Nam, S.; Camuglia, J.; Martin, J. L.; Sanders, E. N.; O'Brien, L. E.; Martin, A. C.; Kim, T.; Chaudhuri, O.
10.1101/2020.11.16.378927 — cell biology — Posted on 2020-11-29
155 Papillary And Reticular Fibroblasts Generate Distinct Microenvironments That Differentially Impact Angiogenesis
Mauroux, A.; Joncour, P.; Gillet, B.; Hugues, S.; Ardidie-Robouant, C.; Marchand, L.; Liabotis, A.; Mailly, P.; Monnot, C.; Germain, S.; Bordes, S.; Closs, B.; Ruggiero, F.; Muller, L.
10.1101/2020.11.29.402594 — cell biology — Posted on 2020-11-29
157 Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection
Kamel, W.; Noerenberg, M.; Cerikan, B.; Chen, H.; Järvelin, A. I.; Kammoun, M.; Lee, J.; Shuai, N.; Garcia-Moreno, M.; Andrejeva, A.; Deery, M. J.; Neufeldt, C. J.; Cortese, M.; Knight, M. L.; Lilley, K. S.; Martinez, J.; Davis, I.; Bartenschlager, R.; Mohammed, S.; Castello, A.
10.1101/2020.11.25.398008 — microbiology — Posted on 2020-11-29
158 Immunofocusing humoral immunity potentiates the functional efficacy of the AnAPN1 malaria transmission-blocking vaccine antigen
Bender, N. G.; Khare, P.; Martinez, J.; Tweedell, R. E.; Nyasembe, V. O.; Lopez-Gutierrez, B.; Tripathi, A.; Miller, D.; Hamerly, T.; Vela, E. M.; Howard, R. F.; Nsango, S.; Cobb, R. R.; Harbers, M.; Dinglasan, R. R.
10.1101/2020.11.29.402669 — immunology — Posted on 2020-11-29
159 Action Observation Network activity related to object-directed and socially directed actions in Adolescents
Lesourd, M.; Afyouni, A.; Geringswald, F.; Cignetti, F.; Raoul, L.; Sein, J.; Nazarian, B.; Anton, J.-L.; Grosbras, M.-H.
10.1101/2020.11.29.402560 — neuroscience — Posted on 2020-11-29
161 Crop-photoperiodism model 2.0 for the panicle-initiation date of sorghum and rice that includes daily changes in sunrise and sunset times
Clerget, B.; Sidibe, M.; Bueno, C. S.; Trouche, G.; Chantereau, J.; Grenier, C.; Kawakata, T.; Domingo, A. J.; Layaoen, H. L.; Palacios, N. G.; Bernal, J. H.
10.1101/2020.11.29.402628 — plant biology — Posted on 2020-11-29
162 VGLL1-directed TEAD activation drives endocrine therapy resistance in estrogen receptor positive breast cancer
Gemma, C.; Singh, A.; Belfiore, A.; Lai, C.; Periyasamy, M.; Abuelmaaty, S.; Davies, C.; Wang, X.; Simmons, G.; Nguyen, V.; Magnani, L.; Rakha, E.; Martin, L.-A.; Coombes, C.; Pruneri, G.; Buluwela, L.; Ali, S.
10.1101/2020.11.29.402842 — cancer biology — Posted on 2020-11-29
163 Seeing the forest through the trees: Identifying functional interactions from Hi-C
Liu, N.; low, w. y.; Alinejad-Rokny, H.; Sadlon, T.; Pederson, S. M.; Barry, S. C.; Breen, J.
10.1101/2020.11.29.402420 — bioinformatics — Posted on 2020-11-29
164 Estimating the timing of HIV infection from unmutated sequences
Pankow, A.; Christian, M.; Smith, N.; Sheward, D. J.; Murrell, B.
10.1101/2020.11.28.402271 — bioinformatics — Posted on 2020-11-29
165 Differentiation of human induced pluripotent stem cells into functional airway epithelium
Ahmed, E.; Fieldes, M.; Bourguignon, C.; Mianne, J.; Petit, A.; Vernisse, C.; Jory, M.; Cazevieille, C.; Boukhaddaoui, H.; Garnett, J. P.; Massiera, G.; Vachier, I.; Assou, S.; Bourdin, A.; De Vos, J.
10.1101/2020.11.29.400358 — bioengineering — Posted on 2020-11-29
166 Performance comparison: exome-sequencing as a single test replacing Sanger-sequencing
Fridman, H.; Bormans, C.; Einhorn, M.; Au, D.; Bormans, A.; Porat, Y.; Sanchez, L. F.; Manning, B.; Levy-Lahad, E.; Behar, D. M.
10.1101/2020.11.29.400853 — genetics — Posted on 2020-11-29
167 Variant Curation Expert Panel Recommendations for RYR1 Pathogenicity Assertions in Malignant Hyperthermia Susceptibility
Johnston, J. J.; Dirksen, R. T.; Girard, T.; Gonsalves, S. G.; Hopkins, P. M.; Riazi, S.; Saddic, L. A.; Sambuughin, N.; Saxena, R.; Stowell, K.; Weber, J.; Rosenberg, H.; Biesecker, L. G.
10.1101/2020.11.29.402768 — genetics — Posted on 2020-11-29
169 CSF1R-dependent macrophages control postnatal somatic growth and organ maturation.
Keshvari, s.; Caruso, M.; Batoon, L.; Sehgal, A.; Teakle, N.; Patkar, O.; Chen, C.; Snell, C. E.; Stevenson, A.; Davis, F. M.; Bush, S. J.; Pridans, C.; Summers, K. M.; Irvine, K. M.; Hume, D. A.
10.1101/2020.11.29.402859 — developmental biology — Posted on 2020-11-29
171 Amplicon and metagenomic analysis of MERS-CoV and the microbiome in patients with severe Middle East respiratory syndrome (MERS)
Aljabr, W.; Alruwaili, M.; Penrice-Randal, R.; Alrezaihi, A.; Harrison, A. J.; Ryan, Y.; Bentley, E.; Jones, B.; Alhatlani, B. Y.; AlShahrani, D.; Mahmood, Z.; Rickett, N. J.; Alosaimi, B.; Naeem, A.; Alamri, S.; Alsran, H.; Hamed, M. E.; Dong, X.; Assiri, A.; Alrasheed, A.; Hamza, M.; Carroll, M. W.; Gemmell, M.; Darby, A.; Donovan-Banfield, I.; Stewart, J. P.; Matthews, D. A.; Davidson, A. D.; Hiscox, J. A.
10.1101/2020.11.28.400671 — molecular biology — Posted on 2020-11-29
180 Demographics and Employment of Max-Planck Society's Postdocs
Vallier, M.; Mueller, M.; Alcami, P.; Bellucci, G.; Grange, M.; Lu, Y.-X.; Duponchel, S.
10.1101/2020.11.27.399733 — scientific communication and education — Posted on 2020-11-29
181 Bringing BOS to light: Uncovering the key enzyme in the biosynthesis of the neurotoxin β-ODAP in Grass Pea (Lathyrus sativus L.)
Goldsmith, M.; Barad, S.; Knafo, M.; Savidor, A.; Ben-Dor, S.; Brandis, A.; Mehlman, T.; Peleg, Y.; Albeck, S.; Dym, O.; Benzeev, E.; Reich, Z.
10.1101/2020.11.29.402396 — plant biology — Posted on 2020-11-29
182 SLC7A11 is a superior determinant of APR-246 (Eprenetapopt) response than TP53 mutation status
Fujihara, K. M.; Corrales-Benitez, M.; Cabalag, C. S.; Zhang, B. Z.; Ko, H. S.; Liu, D. S.; Simpson, K. J.; Haupt, Y.; Haupt, S.; Phillips, W. A.; Clemons, N. J.
10.1101/2020.11.29.398875 — cancer biology — Posted on 2020-11-29
183 Predicting and validating protein degradation in proteomes using deep learning
Ozols, M.; Eckersley, A.; Platt, C.; Mcguinness, C. S.; Hibbert, S.; Revote, J.; Li, F.; Griffiths, C.; Watson, R.; Song, J.; Bell, M.; Sherratt, M.
10.1101/2020.11.29.402446 — bioinformatics — Posted on 2020-11-29
188 Regulating enzymatic reactions in Escherichia coli utilizing light-responsive cellular compartments based on liquid-liquid phase separation
Huang, Z.; Sun, L.; Lu, G.; Liu, H.; Zhai, Z.; Feng, S.; Gao, J.; Chen, C.; Qing, C.; Fang, M.; Chen, B.; Fu, J.; Wang, X.; Chen, G.-Q.
10.1101/2020.11.26.395616 — synthetic biology — Posted on 2020-11-29
191 Whole slide imaging is a high-throughput method to assess Candida biofilm formation
Raas, M. W. D.; Silva, T. P.; Freitas, J. O. C.; Campos, L. M.; Fabri, R. L.; Melo, R. C.
10.1101/2020.03.15.992735 — microbiology — Posted on 2020-11-29
192 Predicting and validating protein degradation in proteomes using deep learning
Ozols, M.; Eckersley, A.; Platt, C.; Mcguinness, C. S.; Hibbert, S.; Revote, J.; Li, F.; Griffiths, C.; Watson, R.; Song, J.; Bell, M.; Sherratt, M.
10.1101/2020.11.29.402446 — bioinformatics — Posted on 2020-11-29
195 Rare Genetic Variation Underlying Human Diseases and Traits: Results from 200,000 Individuals in the UK Biobank
Jurgens, S. J.; Choi, S. H.; Morrill, V. N.; Chaffin, M.; Pirruccello, J. P.; Halford, J. L.; Weng, L.-C.; Nauffal, V.; Roselli, C.; Hall, A. W.; Aragam, K.; Lunetta, K. L.; Lubitz, S. A.; Ellinor, P. T.
10.1101/2020.11.29.402495 — genetics — Posted on 2020-11-29
196 First demonstration of the FLASH effect with ultrahigh dose-rate high energy X-rays
Gao, F.; Yang, Y.; Zhu, H.; Wang, J.; Xiao, D.; Zhou, Z.; Dai, T.; Zhang, Y.; Feng, G.; Li, J.; Lin, B.; Xie, G.; Ke, Q.; Li, P.; Sheng, X.; Wang, H.; Yan, L.; Lao, C.; Li, M.; Lu, Y.; Zhao, J.; Feng, S.; Du, X.; Wu, D.
10.1101/2020.11.27.401869 — cancer biology — Posted on 2020-11-29
197 A highly contiguous genome assembly of a major forest pest, the Eurasian spruce bark beetle Ips typographus
Powell, D.; Grosse-Wilde, E.; Krokene, P.; Roy, A.; Chakraborty, A.; Lofstedt, C.; Vogel, H.; Andersson, M. N.; Schlyter, F.
10.1101/2020.11.28.401976 — genomics — Posted on 2020-11-29
198 A fish-specific new gene evolves new functions in cichlid fishes
Gu, L.; Li, C.; Mao, X.; Wei, Z.; Huang, Y.; He, X.; Zhou, W.; Li, L.; Wang, D.
10.1101/2020.11.28.391342 — evolutionary biology — Posted on 2020-11-29
200 Broadening the ecology of fear: non-lethal effects arise from diverse responses to predation and parasitism
Daversa, D. R.; Hechinger, R. F.; Madin, E.; Fenton, A.; Dell, A. I.; Ritchie, E.; Rohr, J.; Rudolph, V. H. W.
10.1101/766477 — ecology — Posted on 2020-11-29
201 Genetic basis for the essentiality of a bacterial anti-sigma factor involved in virulence
Schofield, M. C.; Rodriguez, D.; Kidman, A. A.; Michaels, L. A.; Campbell, E. A.; Jorth, P. A.; Tseng, B. S.
10.1101/2020.08.17.253617 — microbiology — Posted on 2020-11-29
202 Pfcerli2, a duplicated gene in the malaria parasite Plasmodium falciparum essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysis.
Liffner, B.; Balbin, J. M.; Shami, G. J.; Strauss, J.; Frolich, S.; Heinemann, G. K.; Alder, A.; Wichers, J. S.; Tilley, L.; Dixon, M. W. A.; Gilberger, T. W.; Wilson, D. W.
10.1101/2020.11.26.400549 — microbiology — Posted on 2020-11-29
208 Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
Teano, G.; Concia, L.; Carron, L.; Wolff, L.; Adamusova, K.; Fojtova, M.; Bourge, M.; Kramdi, A.; Colot, V.; Grossniklaus, U.; Bowler, C.; Baroux, C.; Carbonne, A.; Probst, A. V.; Prochazkova Schrumpfova, P.; Fajkus, J.; Amiard, S.; Grob, S.; Bourbousse, C.; Barneche, F.
10.1101/2020.11.28.402172 — molecular biology — Posted on 2020-11-28
210 Stool serology: development of a non-invasive immunological method for the detection of Enterovirus-specific antibodies in Congo gorilla feces
SEREME, Y.; ZARZA, S. M.; MEDKOUR, H.; Amona, I.; Fenollar, F.; Akiana, J.; Mezouar, S.; Orain, N.; Vitte, J.; Davoust, B.; Raoult, D.; Mediannikov, O.
10.1101/2020.11.28.402230 — microbiology — Posted on 2020-11-28
215 Cryptic promoter activation occurs by at least two different mechanisms in the Arabidopsis genome
Kudo, H.; Matsuo, M.; Satoh, S.; Hachisu, R.; Nakamura, M.; Yamamoto, Y. Y.; Hata, T.; Kimura, H.; Matsui, M.; Obokata, J.
10.1101/2020.11.28.399337 — evolutionary biology — Posted on 2020-11-28
219 First demonstration of the FLASH effect with ultrahigh dose-rate high energy X-rays
Gao, F.; Yang, Y.; Zhu, H.; Wang, J.; Xiao, D.; Zhou, Z.; Dai, T.; Zhang, Y.; Feng, G.; Li, J.; Lin, B.; Xie, G.; Ke, Q.; Li, P.; Sheng, X.; Wang, H.; Yan, L.; Lao, C.; Li, M.; Lu, Y.; Zhao, J.; Feng, S.; Du, X.; Wu, D.
10.1101/2020.11.27.401869 — cancer biology — Posted on 2020-11-28
221 MolDiscovery: Learning Mass Spectrometry Fragmentation of Small Molecules
Cao, L.; Guler, M.; Tagirdzhanov, A.; Lee, Y.; Gurevich, A.; Mohimani, H.
10.1101/2020.11.28.401943 — bioinformatics — Posted on 2020-11-28
225 Efficient design of maximally active and specific nucleic acid diagnostics for thousands of viruses
Metsky, H. C.; Welch, N. L.; Haradhvala, N. J.; Rumker, L.; Zhang, Y. B.; Pillai, P. P.; Yang, D. K.; Ackerman, C. M.; Weller, J.; Blainey, P. C.; Myhrvold, C.; Mitzenmacher, M.; Sabeti, P. C.
10.1101/2020.11.28.401877 — genomics — Posted on 2020-11-28
226 A highly contiguous genome assembly of a major forest pest, the Eurasian spruce bark beetle Ips typographus
Powell, D.; Grosse-Wilde, E.; Krokene, P.; Roy, A.; Chakraborty, A.; Lofstedt, C.; Vogel, H.; Andersson, M. N.; Schlyter, F. N.
10.1101/2020.11.28.401976 — genomics — Posted on 2020-11-28
227 A fish-specific new gene evolves new functions in cichlid fishes
Gu, L.; Li, C.; Mao, X.; Wei, Z.; Huang, Y.; He, X.; Zhou, W.; Li, L.; Wang, D.
10.1101/2020.11.28.391342 — evolutionary biology — Posted on 2020-11-28
228 Phenotypic plasticity, population structure and adaptation in a young weed species with a worldwide distribution
Cornille, A.; Tiret, M.; Salcedo, A.; Huang, H.; Orsucci, M.; Milesi, P.; Kryvokhyzha, D.; Holm, K.; Ge, X. J.; Stinchcombe, J. R.; Glemin, S.; Wright, S.; Lascoux, M.
10.1101/2020.11.27.401562 — evolutionary biology — Posted on 2020-11-28
231 De novo activated transcription of newborn coding sequences is inheritable in the plant genome
Hata, T.; Takada, N.; Hayakawa, C.; Kazama, M.; Uchikoba, T.; Tachikawa, M.; Matsuo, M.; Satoh, S.; Obokata, J.
10.1101/2020.11.28.402032 — evolutionary biology — Posted on 2020-11-28
233 The Coding And Small-Non-Coding Hippocampal Synaptic RNAome
Epple, R.; Krueger, D. M.; Berulava, T.; Brehm, G.; Islam, R.; Koester, S.; Fischer, A.
10.1101/2020.11.27.401901 — neuroscience — Posted on 2020-11-28
235 Disruption of orbitofrontal-hypothalamic projections in a murine ALS model and human patients
Bayer, D.; Antonucci, S.; Mueller, H.-P.; Dupuis, L.; Boeckers, T. M.; Ludolph, A. C.; Kassubek, J.; Roselli, F.
10.1101/2020.11.28.402065 — neuroscience — Posted on 2020-11-28
238 Biomedical Graph Visualizer for Identifying Drug Candidates
Teng, A.; Villanueva, B.; Jow, D. R.; Huang, S.-C.; Piekos, S. N.; Altman, R. B.
10.1101/2020.11.27.368811 — bioinformatics — Posted on 2020-11-28
240 Molecular and electrophysiological features of spinocerebellar ataxia type seven in induced pluripotent stem cells
Burman, R. J.; Watson, L. M.; Smith, D. C.; Raimondo, J. V.; Ballo, R.; Scholefield, J.; Cowley, S. A.; Wood, M. J.; Kidson, S. H.; Greenberg, L. J.
10.1101/288480 — neuroscience — Posted on 2020-11-28
241 Transcriptomic Analysis of Early Stages of Intestinal Regeneration in Holothuria glaberrima
Quispe-Parra, D. J.; Medina-Feliciano, J. G.; Cruz-Gonzalez, S.; Ortiz-Zuazaga, H.; Garcia-Arraras, J. E.
10.1101/2020.09.23.310599 — bioinformatics — Posted on 2020-11-28
242 β-catenin signaling via astrocyte-encoded TCF7L2 regulates neuronal excitability and social behavior
Szewczyk, L. M.; Lipiec, M. A.; Liszewska, E.; Urban-Ciecko, J.; Kondrakiewicz, L.; Puscian, A.; Knapska, E.; Inoue, H.; Nowakowski, T. J.; Molofsky, A. V.; Wisniewska, M. B.
10.1101/2020.11.28.402099 — neuroscience — Posted on 2020-11-28
243 Cell segmentation-free inference of cell types from in situ transcriptomics data
Park, J.; Choi, W.; Tiesmeyer, S.; Long, B.; Borm, L. E.; Garren, E.; Nguyen, T. N.; Tasic, B.; Codeluppi, S.; Graf, T.; Schlesner, M.; Stegle, O.; Eils, R.; Ishaque, N.
10.1101/800748 — bioinformatics — Posted on 2020-11-28
245 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2020-11-28
247 Bradyrhizobium diazoefficiens USDA110 nodulation of Aeschynomene afraspera is associated with atypical terminal bacteroid differentiation and suboptimal symbiotic efficiency
Nicoud, Q.; Lamouche, F.; Chaumeret, A.; Balliau, T.; Le Bars, R.; Bourge, M.; Pierre, F.; Guerard, F.; Sallet, E.; Tuffigo, S.; Pierre, O.; Dessaux, Y.; Gilard, F.; Gakiere, B.; Nagy, I.; Kereszt, A.; Zivy, M.; Mergaert, P.; Gourion, B.; Alunni, B.
10.1101/2020.11.24.397182 — microbiology — Posted on 2020-11-28
249 DNA polymerase theta suppresses mitotic crossing over
Carvajal-Garcia, J.; Crown, K. N.; Ramsden, D. A.; Sekelsky, J.
10.1101/2020.11.27.400952 — genetics — Posted on 2020-11-27
251 Differential host response to a herpesvirus: Mareks disease virus peptides on chicken MHC class II molecules are derived from only a few genes and illustrate a new mode of peptide binding
Halabi, S.; Ghosh, M.; Stevanovic, S.; Rammensee, H.-G.; Bertzbach, L. D.; Kaufer, B. B.; Moncrieffe, M. C.; Kaspers, B.; Härtle, S.; Kaufman, J.
10.1101/2020.11.27.400937 — immunology — Posted on 2020-11-27
256 Characterisation and chemometric evaluation of 17 elements in ten seaweed species from Greenland
Kreissig, K. J.; Hansen, L. T.; Jensen, P. E.; Wegeberg, S.; Geertz-Hansen, O.; Sloth, J. J.
10.1101/2020.11.27.400861 — biochemistry — Posted on 2020-11-27
260 Mfd affects global transcription and the physiology of stressed Bacillus subtilis cells
Martin, H. A.; Sundararajan, A.; Ermi, T. S.; Heron, R.; Gonzales, J.; Lee, K.; Pedraza-Reyes, M.; Robleto, E. A.
10.1101/2020.11.27.401687 — microbiology — Posted on 2020-11-27
263 Comparative analysis of early divergent land plants and construction of DNA tools for hyper-expression in Marchantia chloroplasts
Frangedakis, E.; Guzman-Chavez, F.; Rebmann, M.; Markel, K.; Yu, Y.; Perraki, A.; Tse, S. W.; Liu, Y.; Rever, J.; Sauret-Gueto, S.; Goffinet, B.; Schneider, H.; Haseloff, J.
10.1101/2020.11.27.401802 — plant biology — Posted on 2020-11-27
270 Phenotypic plasticity of ER+ breast cancer in the bone microenvironment
Bado, I. L.; Wang, H.; Sarkar, P.; Liu, J.; Wu, W.; Zhang, W.; Lo, H.-C.; Muscallera, A.; Janghorban, M.; Kim, I.-S.; Singh, S.; Goldstein, A.; Singh, P.; Shixia, H.; Waleed, G. M.; Ellis, M. J.; Zhang, X. H. F.
10.1101/2020.11.14.383000 — cancer biology — Posted on 2020-11-27
271 The bone microenvironment invigorates metastatic seeds for further dissemination
Zhang, W.; Bado, I. L.; Wang, H.; Singh, S.; Lo, H.-C.; Niu, M.; Xu, Z.; Liu, J.; Jiang, W.; Li, Y.; Hu, J.; Zhang, X. H. - F.
10.1101/2020.11.16.383828 — cancer biology — Posted on 2020-11-27
273 Ablation of Proliferating Osteoblast Lineage Cells After Fracture Leads to Atrophic Nonunion in a Mouse Model
Hixon, K. R.; Sykes, D. A.; Yoneda, S.; McKenzie, J. A.; Hensley, A.; Buettmann, E. G.; Skouteris, D.; Miller, A. N.; Silva, M. J.
10.1101/2020.10.06.327288 — bioengineering — Posted on 2020-11-27
275 Overcoming uncollapsed haplotypes in long-read assemblies of non-model organisms
Guiglielmoni, N.; Houtain, A.; Derzelle, A.; van Doninck, K.; Flot, J.-F.
10.1101/2020.03.16.993428 — genomics — Posted on 2020-11-27
276 Diverse molecular mechanisms contribute to differential expression of human duplicated genes
Shew, C. J.; Carmona-Mora, P.; Soto, D. C.; Mastoras, M.; Roberts, E.; Rosas, J.; Jagannathan, D.; Kaya, G.; O'Geen, H.; Dennis, M. Y.
10.1101/2020.11.27.401752 — genomics — Posted on 2020-11-27
277 Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk
Twigger, A.-J.; Engelbrecht, L. K.; Bach, K.; Schultz-Pernice, I.; Petricca, S.; Scheel, C. H.; Khaled, W.
10.1101/2020.11.06.371443 — cell biology — Posted on 2020-11-27
278 Organization of Peptidoglycan Synthesis in Nodes and Separate Rings at Different Stages of Cell Division of Streptococcus pneumoniae
Perez, A. J.; Boersma, M. J.; Bruce, K. E.; Lamanna, M. M.; Shaw, S. L.; Tsui, H.-C. T.; Taguchi, A.; Carlson, E. E.; VanNieuwenhze, M. S.; Winkler, M. E.
10.1101/2020.09.27.315481 — microbiology — Posted on 2020-11-27
286 Decoding neural responses to motion-in-depth using EEG
Himmelberg, M. M.; Segala, F. G.; Maloney, R. T.; Harris, J. M.; Wade, A. R.
10.1101/661991 — neuroscience — Posted on 2020-11-27
287 Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist
Isaikina, P.; Tsai, C.-J.; Dietz, N. B.; Pamula, F.; Grahl, A.; Goldie, K. N.; Guixa-Gonzalez, R.; Schertler, G. F. X.; Hartley, O.; Stahlberg, H.; Maier, T.; Deupi, X.; Grzesiek, S.
10.1101/2020.11.27.401117 — biophysics — Posted on 2020-11-27
291 Rat perichondrium transplanted to articular cartilage defects forms articular-like, hyaline cartilage
Dou, Z.; Muder, D.; Baroncelli, M.; Bendre, A.; Gkourogianni, A.; Ottosson, L.; Vedung, T.; Nilsson, O.
10.1101/2020.11.27.401091 — developmental biology — Posted on 2020-11-27
292 Highly functional virus-specific cellular immune response in asymptomatic SARS-CoV-2 infection
Le Bert, N.; Clapham, H. E.; Tan, A. T.; Chia, W. N.; Tham, C. Y.; Lim, J. M.; Kunasegaran, K.; Tan, L.; Dutertre, C.-A.; Shankar, N.; Lim, J. M.; Sun, L. J.; Zahari, M.; Tun, Z. M.; Kumar, V.; Lim, B. L.; Lim, S. H.; Chia, A.; Tan, Y.-J.; Tambyah, P. A.; Kalimuddin, S.; Lye, D. C.; Low, J. G.; Wang, L.-F.; Wan, W. Y.; Hsu, L. Y.; Bertoletti, A.; Tam, C. C.
10.1101/2020.11.25.399139 — immunology — Posted on 2020-11-27
293 A Novel Cell Therapy for COVID-19 and Potential Future Pandemics: Virus Induced Lymphocytes (VIL)
Sivapalan, R.; Liu, J.; Chakraborty, K.; Arthofer, E.; Choudhry, M.; Barie, P. S.; Barouch, D. H.; Henley, T.
10.1101/2020.11.26.400390 — immunology — Posted on 2020-11-27
294 Measuring stimulus-evoked neurophysiological differentiation in distinct populations of neurons in mouse visual cortex
Mayner, W. G. P.; Marshall, W.; Billeh, Y. N.; Gandhi, S. R.; Caldejon, S.; Cho, A.; Griffin, F.; Hancock, N.; Lambert, S.; Lee, E.; Luviano, J.; Mace, K.; Nayan, C.; Nguyan, T.; North, K.; Seid, S.; Williford, A.; Cirelli, C.; Groblewski, P.; Lecoq, J.; Tononi, G.; Koch, C.; Arkhipov, A.
10.1101/2020.11.27.400457 — neuroscience — Posted on 2020-11-27
298 A mechanism for hippocampal memory recall based on excitatory-inhibitory fluctuations in neocortex
Koolschijn, R. S.; Shpektor, A.; Ip, I. B.; Clarke, W. T.; Dupret, D.; Emir, U. E.; Barron, H. C.
10.1101/2020.11.27.401299 — neuroscience — Posted on 2020-11-27
301 Human induced pluripotent stem cell-derived arteries as personalized models of atherosclerosis on-a-chip
Mallone, A.; Gericke, C.; Hosseini, V.; Vogel, V.; Chahbi, K.; Walther, J. H.; Haenseler, W.; Eckardstein, A. v.; Emmert, M. Y.; Weber, B.; Hoerstrup, S. P.
10.1101/2020.11.27.401034 — bioengineering — Posted on 2020-11-27
302 Profiling Germline Adaptive Immune Receptor Repertoire with gAIRR Suite
Lin, M.-J.; Lin, Y.-C.; Chen, N.-C.; Luo, A. C.-L.; Lai, S.-K.; Hsu, C.-L.; Hsu, J. S.; Chen, C.-Y.; Yang, W.-S.; Chen, P.-L.
10.1101/2020.11.27.399857 — genomics — Posted on 2020-11-27
305 CRISPR/Cas9 targeting Ttc30a mimics ciliary chondrodysplasia with polycystic kidney disease.
Getwan, M.; Hoppmann, A.; Schlosser, P.; Grand, K.; Song, W.; Diehl, R.; Schroda, S.; Heeg, F.; Deutsch, K.; Hildebrandt, F.; Lausch, E.; Koettgen, A.; Lienkamp, S. S.
10.1101/2020.11.27.400994 — developmental biology — Posted on 2020-11-27
306 3D super-resolution fluorescence microscopy maps the variable molecular architecture of the Nuclear Pore Complex
Jimenez Sabinina, V.; Hossain, M. J.; Heriche, J.-K.; Hoess, P.; Nijmeijer, B.; Mosalaganti, S.; Kueblbeck, M.; Callegari, A.; Szymborska, A.; Beck, M.; Ries, J.; Ellenberg, J.
10.1101/2020.11.27.386599 — cell biology — Posted on 2020-11-27
307 Structural basis for variable IgE reactivities of Cor a 1 hazelnut allergens
Fuehrer, S.; Kamenik, A. S.; Zeindl, R.; Nothegger, B.; Hofer, F.; Reider, N.; Liedl, K. R.; Tollinger, M.
10.1101/2020.11.27.400978 — molecular biology — Posted on 2020-11-27
308 Machine learning-based clustering of nanosized fluorescent extracellular vesicles
Kuypers, S.; Smisdom, N.; Pintelon, I.; Timmermans, J.-P.; Ameloot, M.; Michiels, L.; Hendrix, J.; Hosseinkhani, B.
10.1101/2020.11.27.374728 — molecular biology — Posted on 2020-11-27
309 Establishment of Culex modestus in Belgium and a glance into the virome of Belgian mosquito species
Wang, L.; Rosales Rosas, A. L.; De Coninck, L.; Shi, C.; Bouckaert, J.; Matthijnssens, J.; Delang, L.
10.1101/2020.11.27.401372 — microbiology — Posted on 2020-11-27
311 The Dutch Microbiome Project defines factors that shape the healthy gut microbiome
Gacesa, R.; Kurilshikov, A.; Vich Vila, A.; Sinha, T.; Klaassen, M. A. Y.; Bolte, L. A.; Andreu-Sanchez, S.; Chen, L.; Collij, V.; Hu, S.; Dekens, J. A. M.; Lenters, V. C.; Bjork, J. R.; Swarte, J. C.; Swertz, M. A.; Jansen, B. H.; Gelderloos-Arends, J.; Lifelines cohort study, ; Hofker, M.; Vermeulen, R. C. H.; Sanna, S.; Harmsen, H. J. M.; Wijmenga, C.; Fu, J.; Zhernakova, A.; Weersma, R. K.
10.1101/2020.11.27.401125 — microbiology — Posted on 2020-11-27
312 Sleeping ribosomes: bacterial signaling triggers RaiA mediated persistence to aminoglycosides.
Lang, M.; Krin, E.; Korlowski, C.; Sismeiro, O.; Varet, H.; Coppee, J.-Y.; Mazel, D.; Baharoglu, Z.
10.1101/2020.11.27.401281 — microbiology — Posted on 2020-11-27
314 A one-shot learning signal in monkey prefrontal cortex
Achterberg, J.; Kadohisa, M.; Watanabe, K.; Kusunoki, M.; Buckley, M. J.; Duncan, J.
10.1101/2020.11.27.401422 — neuroscience — Posted on 2020-11-27
318 Seeded assembly in vitro does not replicate the structures of α-synuclein filaments from multiple system atrophy
Lövestam, S.; Schweighauser, M.; Saito, Y.; Murayama, S.; Tomita, T.; Ando, T.; Hasegawa, K.; Yoshida, M.; Tarutani, A.; Hasegawa, M.; Goedert, M.; Scheres, S.
10.1101/2020.11.27.401364 — molecular biology — Posted on 2020-11-27
320 Whole-brain dynamics of human sensorimotor adaptation
Standage, D. I.; Areshenkoff, C. N.; Gale, D. J.; Nashed, J. Y.; Flanagan, J. R.; Gallivan, J. P.
10.1101/2020.11.27.401679 — neuroscience — Posted on 2020-11-27
321 LARP6C regulates selective mRNA translation to promote pollen tube guidance in Arabidopsis thaliana.
Billey, E.; Hafidh, S.; Cruz-Gallardo, I.; Litholdo, C. G.; Jean, V.; Carpentier, M.-C.; Picart, C.; Kulichova, K.; Honys, D.; Deragon, J.-M.; Bousquet-Antonelli, C.
10.1101/2020.11.27.401307 — plant biology — Posted on 2020-11-27
327 Divergent pallidal pathways underlying distinct Parkinsonian behavioral deficits
Lim, B.; Lilascharoen, V.; Wang, E. H.-J.; Do, N.; Pate, S. C.; Tran, A. N.; Wang, X.-Y.; Park, Y.-G.; Chung, K.
10.1101/2020.11.27.401554 — neuroscience — Posted on 2020-11-27
332 Keratin-Based Epidermal Green Autofluorescence is a Common Biomarker of Organ Injury
Zhang, M.; Li, Y.; Wang, J.; Yang, Z.; Wu, D.; Tao, Y.; He, H.; Yang, Z.; Maharjan, D. T.; Tang, H.; Wang, S.; Chen, X.; Jin, L.; Ying, W.; Wang, Y.; Wei, X.; Shi, H.; Yin, S.
10.1101/564112 — biophysics — Posted on 2020-11-27
334 A spontaneous genetically-induced epiallele at a retrotransposon shapes host genome function
Bertozzi, T. M.; Hanin, G.; Takahashi, N.; Kazachenka, A.; Ferguson-Smith, A. C.
10.1101/2020.11.27.401547 — genetics — Posted on 2020-11-27
339 Identification of Gli1 as a progenitor cell marker for meniscus development and injury repair
Qin, L.; Wei, Y.; Sun, H.; Gui, T.; Yao, L.; Zhong, L.; Yu, W.; Heo, S.-J.; Han, L.; Liu, X. S.; Zhang, Y.; Koyama, E.; Long, F.; Zgonis, M. H.; Mauck, R.; Ahn, J.
10.1101/2020.11.27.401463 — developmental biology — Posted on 2020-11-27
340 Signals Secreted by Infection Induce Transcriptional and Epigenetic Changes in Neurons
McConkey, G. A.; Tedford, E.; Filippi, B. M.; Laing, C.; Badya, N. B.; Asaoka, N.; Kaneko, S.
10.1101/2020.11.26.399345 — microbiology — Posted on 2020-11-27
342 Screening of FDA-approved drugs using a MERS-CoV clinical isolate from South Korea identifies potential therapeutic options for COVID-19
Ko, M.; Chang, S. Y.; Byun, S. Y.; Ianevski, A.; Choi, I.; d'Alexandry d'Orengiani, A. L. P. H.; Kainov, D.; Shum, D.; Min, J.-Y.; Windisch, M. P.
10.1101/2020.02.25.965582 — microbiology — Posted on 2020-11-27
346 Elevated expression of complement C4 in the mouse prefrontal cortex causes schizophrenia-associated phenotypes
Druart, M.; Nosten-Bertrand, M.; Poll, S.; Crux, S.; Nebeling, F.; Delhaye, C.; Dubois, Y.; Leboyer, M.; Tamouza, R.; Fuhrmann, M.; Le Magueresse, C.
10.1101/2020.11.27.400960 — neuroscience — Posted on 2020-11-27
347 Distinct role of nucleus accumbens D2-MSN projections to ventral pallidum in different phases of motivated behavior
Soares-Cunha, C.; Correia, R.; Domingues, A. V.; Coimbra, B.; de Vasconcelos, N. A.; Pinto, L.; Sousa, N.; Rodrigues, A. J.
10.1101/2020.11.27.401042 — neuroscience — Posted on 2020-11-27
350 Validation of a novel associative transcriptomics pipeline in Brassica oleracea: Identifying candidates for vernalisation response
Woodhouse, S. M.; He, Z.; Woolfenden, H.; Steuernagel, B.; Haerty, W. `; Bancroft, I.; Irwin, J. `; Morris, R. J.; Wells, R.
10.1101/2020.11.27.400986 — plant biology — Posted on 2020-11-27
351 Spatial heterogeneity of glioblastoma cells reveals sensitivity to NAD+ depletion at tumor edge
Yamashita, D.; Botta, D.; Cho, H. J.; Guo, X.; Ozaki, S.; Flanary, V. L.; Sirota, I.; Gao, M.; Yamaguchi, S.; Nakano, M. A.; Zhou, F.; Zhou, H.; Kondo, T.; Kunieda, T.; Crossman, D.; Kornblum, H.; Gorospe, M.; Nam, D.-H.; Zamboni, N.; Gu, Z.; Lund, F. E.; Nakano, I.
10.1101/2020.11.26.399725 — cancer biology — Posted on 2020-11-27
354 Fast and sensitive taxonomic assignment to metagenomic contigs
Mirdita, M.; Steinegger, M.; Breitwieser, F.; Soeding, J.; Levy Karin, E.
10.1101/2020.11.27.401018 — bioinformatics — Posted on 2020-11-27
357 New Structural Insights into the Function of the Catalytically Active Human Taspase1
Nagaratnam, N.; Delker, S.; Jernigan, R.; Edwards, T. E.; Snider, J.; Thifault, D.; Williams, D.; Nannenga, B. L.; Stofega, M.; Sambucetti, L.; Hsieh, J.; Flint, A. J.; Fromme, P.; Martin-Garcia, J. M.
10.1101/2020.11.26.400622 — biochemistry — Posted on 2020-11-27
360 Trends of genetic changes uncovered by Env- and Eigen-GWAS in wheat and barley
Sharma, R.; Cockram, J.; Gardner, K. A.; Russell, J.; Ramsay, L.; Thomas, W. T.; O'Sullivan, D. M.; Powell, W.; Mackay, I. J.
10.1101/2020.11.27.400333 — genetics — Posted on 2020-11-27
361 Heritability of DNA methylation in threespine stickleback (Gasterosteus aculeatus)
Hu, J.; Wuitchik, S. J. S.; Barry, T. N.; Rogers, S. M.; Jamniczky, H. A.; Barrett, R. D. H.
10.1101/2020.11.26.400531 — evolutionary biology — Posted on 2020-11-27
362 Resistance to platinum chemotherapy in lung adenocarcinoma is driven by a non-genetic, cell-cycle dependent mechanism
Gonzalez-Rajal, A.; McCloy, R. A.; Nobis, M.; Marzec, K.; Chin, V.; Hastings, J. F.; Lai, K.; Kennerson, M.; Vaghjiani, V.; Hughes, W. E.; Timpson, P.; Cain, J.; Watkins, D. N.; Croucher, D. R.; Burgess, A.
10.1101/2020.11.26.400499 — cell biology — Posted on 2020-11-27
363 Pfcerli2, a duplicated gene in the malaria parasite Plasmodium falciparum essential for invasion of erythrocytes as revealed by phylogenetic and cell biological analysis.
Liffner, B.; Balbin, J. M.; Shami, G. J.; Strauss, J.; Frolich, S.; Heinemann, G. K.; Alder, A.; Wichers, J. S.; Tilley, L.; Dixon, M. W. A.; Gilberger, T. W.; Wilson, D. W.
10.1101/2020.11.26.400549 — microbiology — Posted on 2020-11-27
366 CA2 inhibition reduces the precision of hippocampal assembly reactivation
He, H.; Boehringer, R.; Huang, A. J. Y.; Overton, E. T. N.; Polygalov, D.; Okanoya, K.; McHugh, T. J.
10.1101/2020.11.26.400655 — neuroscience — Posted on 2020-11-27
367 Patient-derived models of brain metastases recapitulate the histopathology and biology of human metastatic cancers
Faria, C. C.; Custodia, C.; Cascao, R.; Paisana, E.; Carvalho, T.; Pereira, P.; Roque, R.; Pimentel, J.; Miguens, J.; Barata, J. T.
10.1101/2020.11.26.400036 — cancer biology — Posted on 2020-11-27
370 Predicting the impact of sequence motifs on gene regulation using single-cell data
Hepkema, J.; Lee, N. K.; Stewart, B. J.; Ruangroengkulrith, S.; Charoensawan, V.; Clatworthy, M. R.; Hemberg, M.
10.1101/2020.11.26.400218 — bioinformatics — Posted on 2020-11-27
371 FrustratometeR: an R-package to compute Local frustration in protein structures, point mutants and MD simulations
Rausch, A. O.; Freiberger, M. I.; Leonetti, C. O.; Luna, D. M.; Radusky, L. G.; Wolynes, P. G.; Ferreiro, D. U.; Parra, R. G.
10.1101/2020.11.26.400432 — bioinformatics — Posted on 2020-11-27
373 A novel high-accuracy genome assembly method utilizing a high-throughput workflow
Zeng, Q.; Cao, W.; Xing, L.; Qin, G.; Wu, J.; Nagle, M. F.; Xiong, Q.; Chen, J.; Yang, L.; Bajaj, P.; Chitikineni, A.; Zhou, Y.; Yu, Y.; Xu, J.; Nie, X.; Huang, L.; Liu, S.; Safar, J.; Simkova, H.; Song, W.; Guo, B.; Chen, S.; Dolezel, J.; Hao, Z.; Cheng, Q.; Liang, J.; Tang, J.; Cao, A.; Wang, Q.; Lu, X.; Yang, S.; Ma, H.; Liu, J.; Wang, X.; Zhang, H.; Wang, Z.; Ji, W.; Wang, C.; Yuan, F.; Shi, J.; Varshney, R. K.; Kang, Z.; Han, D.; Xu, H.
10.1101/2020.11.26.400507 — genomics — Posted on 2020-11-27
374 Leveraging both individual-level genetic data and GWAS summary statistics increases polygenic prediction
Albinana, C.; Grove, J.; McGrath, J. J.; Agerbo, E.; Wray, N. R.; Werge, T.; Borglum, A. D.; Mortensen, P. B.; Prive, F.; Vilhjalmsson, B. J.
10.1101/2020.11.27.401141 — genetics — Posted on 2020-11-27
380 Loss of choline agonism in the inner ear hair cell nicotinic acetylcholine receptor linked to the α10 subunit
Moglie, M. J.; Marcovich, I.; Corradi, J.; Carpaneto Freixas, A. E.; Gallino, S.; Plazas, P. V.; Bouzat, C.; Lipovsek, M.; Elgoyhen, A. B.
10.1101/2020.11.26.400291 — neuroscience — Posted on 2020-11-27
381 Naturalistic affective behaviors decoded from spectro-spatial features of multi-day human intracranial recordings
Bijanzadeh, M.; Khambhati, A. N.; Desai, M.; Wallace, D. L.; Shafi, A.; Dawes, H. E.; Sturm, V. E.; Chang, E. F.
10.1101/2020.11.26.400374 — neuroscience — Posted on 2020-11-27
390 Robotic Search for Optimal Cell Culture in Regenerative Medicine
Kanda, G. N.; Tsuzuki, T.; Terada, M.; Sakai, N.; Motozawa, N.; Masuda, T.; Nishida, M.; Watanabe, C. T.; Higashi, T.; Horiguchi, S. A.; Kudo, T.; Kamei, M.; Sunagawa, G. A.; Matsukuma, K.; Sakurada, T.; Ozawa, Y.; Takahashi, M.; Takahashi, K.; Natsume, T.
10.1101/2020.11.25.392936 — systems biology — Posted on 2020-11-27
392 Genetics of nodulation in Aeschynomene evenia uncovers new mechanisms of the rhizobium-legume symbiosis
Quilbe, J.; Lamy, L.; Brottier, L.; Leleux, P.; Fardoux, J.; Rivallan, R.; Benichou, T.; Guyonnet, R.; Becana, M.; Villar, I.; Garsmeur, O.; Hufnagel, B.; Delteil, A.; Gully, D.; Chaintreuil, C.; Pervent, M.; Cartieaux, F.; Bourge, M.; Valentin, N.; Martin, G.; Fontaine, L.; Droc, G.; Dereeper, A.; Farmer, A.; Libourel, C.; Nouwen, N.; Gressent, F.; Mournet, P.; d'Hont, A.; Giraud, E.; Klopp, C.; ARRIGHI, J.-F.
10.1101/2020.11.26.399428 — plant biology — Posted on 2020-11-27
394 High throughput functional screening for next generation cancer immunotherapy using droplet-based microfluidics
Wang, Y.; Jin, R.; Shen, B.; Li, N.; Zhou, H.; Wang, W.; Zhao, Y.; Huang, M.; Fang, P.; Wang, S.; Mary, P.; Wang, R.; Ma, P.; Li, R.; Cao, Y.; Li, F.; Schweizer, L.; Zhang, h.
10.1101/2020.11.25.399188 — cancer biology — Posted on 2020-11-27
400 The choice of plant provenance for ecological restoration affects pollinator network
Bucharova, A.; Lampei, C.; Conrady, M.; May, E.; Matheja, J.; Meyer, M.; Ott, D.
10.1101/2020.11.26.399493 — ecology — Posted on 2020-11-27
401 DNA metabarcoding successfully quantifies relative abundances of arthropod taxa in songbird diets: a validation study using camera-recorded diets
Verkuil, Y. I.; Nicolaus, M.; Ubels, R.; Dietz, M. M.; Samplonius, J. M.; Galema, A.; Kiekebos, K.; de Knijff, P.; Both, C.
10.1101/2020.11.26.399535 — ecology — Posted on 2020-11-27
404 High mannose N-glycans on red blood cells as phagocytic ligands, mediating both sickle cell anaemia and resistance to malaria
Cao, H.; Antonopoulos, A.; Henderson, S.; Wassall, H.; Brewin, J.; Masson, A.; Shepard, J.; Konieczny, G.; Patel, B.; Williams, M.-L.; Davie, A. I.; Forrester, M.; Hall, L.; Minter, B.; Tampakis, D.; Moss, M.; Lennon, C.; Pickford, W.; Erwig, L.; Robertson, B.; Dell, A.; Brown, G.; Wilson, H.; Rees, D.; Haslam, S.; Rowe, A. J.; Barker, R. N.; Vickers, M. A.
10.1101/2020.11.26.399402 — immunology — Posted on 2020-11-27
406 Hybrid Hyperalignment: A single high-dimensional model of shared information embedded in cortical patterns of response and functional connectivity
Busch, E. L.; Slipski, L.; Feilong, M.; Guntupalli, J. S.; Visconti di Oleggio Castello, M.; Huckins, J. F.; Nastase, S. A.; Gobbini, M. I.; Wager, T. D.; Haxby, J. V.
10.1101/2020.11.25.398883 — neuroscience — Posted on 2020-11-27
407 Muscle Van Gogh-like 2 shapes the neuromuscular synapse by regulating MuSK signaling activity
Boex, M.; Messeant, J.; Cottin, S.; Halliez, M.; Bauche, S.; Buon, C.; Sans, N.; montcouquiol, m.; Molgo, J.; Amar, M.; Ferry, A.; Lemaitre, M.; Rouche, A.; Langui, D.; Baskaran, A.; Fontaine, B.; Strochlic, L.
10.1101/2020.11.26.384925 — neuroscience — Posted on 2020-11-27
409 Cyber-yeast: Automatic synchronisation of the cell cycle in budding yeast through closed-loop feedback control
Perrino, G.; Napolitano, S.; Galdi, F.; La Regina, A.; Fiore, D.; Giuliano, T.; di Bernardo, M.; di Bernardo, D.
10.1101/2020.11.25.398768 — synthetic biology — Posted on 2020-11-27
411 Arabidopsis bZIP11 is a susceptibility factor during Pseudomonas syringae infection
Prior, M. J.; Selvanayagam, J.; Kim, J.-G.; Tomar, M.; Jonikas, M. C.; Mudgett, M. B.; Smeekens, S.; Hanson, J.; Frommer, W. B.
10.1101/2020.11.25.398727 — plant biology — Posted on 2020-11-27
412 Identification of mutations that cooperate with defects in B cell transcription factors to initiate leukemia
Heltemes-Harris, L. M.; Hubbard, G.; LaRue, R. S.; Munro, S. A.; Knutson, T. P.; Yang, R.; Henzler, C. M.; Starr, T. K.; Sarver, A. L.; Kornblau, s. M.; Farrar, M. A.
10.1101/2020.11.25.398966 — cancer biology — Posted on 2020-11-27
413 3D Adaptive Optical Nanoscopy for Thick Specimen Imaging at sub-50 nm Resolution
Hao, X.; Allgeyer, E. S.; Antonello, J.; Watters, K.; Gerdes, J. A.; Schroeder, L. K.; Bottanelli, F.; Zhao, J.; Kidd, P.; Lessard, M. D.; Rothman, J. E.; Cooley, L.; Biederer, T.; Booth, M. J.; Bewersdorf, J.
10.1101/2020.11.25.398958 — biophysics — Posted on 2020-11-27
419 Eosinophil peroxidase induces inflammation in an animal model of dermatitis
Roth-Carter, Q.; Luo, H.; Ochkur, S. I.; Jacobsen, E.; Datena, M.; Fryer, A. D.; Lee, J. J.; Jacoby, D. B.
10.1101/2020.11.25.399006 — immunology — Posted on 2020-11-27
421 Electrophysiological signatures of acute systemic lipopolysaccharide: potential implications for delirium science
Sultan, Z. W.; Jaeckel, E. R.; Krause, B. M.; Grady, S. M.; Murphy, C. A.; Sanders, R. D.; Banks, M. I.
10.1101/2020.11.25.398388 — neuroscience — Posted on 2020-11-27
424 Targeting Oncogenic Src Homology 2 Domain-Containing Phosphatase 2 (SHP2) by Inhibiting its Protein-Protein Interactions
Bobone, S.; Pannone, L.; Biondi, B.; Solman, M.; Flex, E.; Canale, V.; Calligari, P.; De Faveri, C.; Gandini, T.; Quercioli, A.; Torini, G.; Venditti, M.; Lauri, A.; Fasano, G.; Hoeksma, J.; Santucci, V.; Cattani, G.; Bocedi, A.; Carpentieri, G.; Tirelli, V.; Sanchez, M.; Peggion, C.; Formaggio, F.; Den Hertog, J.; Martinelli, S.; Bocchinfuso, G.; Tartaglia, M.; Stella, L.
10.1101/2020.08.28.271809 — biophysics — Posted on 2020-11-27
425 Transcriptional regulation of structural and functional adaptations in a developing adulthood myocardium
Sunny, S.; Challa, A. K.; Barchue, J. P.; Ramamurthy, M. T.; Crossman, D. K.; Pogwizd, S.; Cinghu, S.; Namakkal-Soorappan, R.
10.1101/2020.11.25.397885 — genomics — Posted on 2020-11-27
426 Physiological role of the 3'IgH CBEs super-anchor in antibody class switching
Zhang, X.; Yoon, H.; Chapdelaine-Williams, A. M.; Kyritsis, N.; Alt, F. W.
10.1101/2020.11.25.398404 — immunology — Posted on 2020-11-27
427 Serum Metabolites Associate with Brain Amyloid Beta Deposition, Cognitive Dysfunction, and Alzheimers Disease Progression
Nho, K.; Kueider-Paisley, A.; Arnold, M.; MahmoudianDehkordi, S.; Risacher, S. L.; Louie, G.; Blach, C.; Baillie, R.; Han, X.; Kastenmüller, G.; Doraiswamy, P. M.; Kaddurah-Daouk, R.; Saykin, A. J.; Alzheimer's Disease Neuroimaging Initiative, ; Alzheimer's Disease Metabolomics Consortium,
10.1101/2020.11.25.394262 — neuroscience — Posted on 2020-11-27
429 Establishment of Multi-stage Models of Drug Taking and Seeking in Mice
Slosky, L. M.; Pires, A.; Bai, Y.; Clark, N.; Hauser, E. R.; Gross, J. D.; Porkka, F.; Pogorelov, V. M.; Toth, K.; Wetsel, W. C.; Barak, L. S.; Caron, M. G.
10.1101/2020.11.25.398503 — neuroscience — Posted on 2020-11-27
434 Discovery of Small-Molecule Antagonists of the PWWP Domain of NSD2
Ferreira de Freitas, R.; Liu, Y.; Szewczyk, M.; Mehta, N.; Li, F.; McLeod, D.; Zepeda-Velazquez, C.; Dilworth, D.; Hanley, R. P.; Gibson, E.; Brown, P. J.; Al-Awar, R.; Ingerman James, L.; Arrowsmith, C. H.; Barsyte-Lovejoy, D.; Min, J.; Vedadi, M.; Schapira, M.; Allali-Hassani, A.
10.1101/2020.11.25.398586 — pharmacology and toxicology — Posted on 2020-11-27
436 The complex history of genome duplication andhybridization in North American gray treefrogs
Booker, W. W.; Gerhardt, H. C.; Lemmon, A. R.; Ptacek, M.; Hassinger, A. T.; Schul, J.; Lemmon, E. M.
10.1101/2020.11.25.398461 — genomics — Posted on 2020-11-27
438 A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation
Wyatt, C. D. R.; Pernaute, B.; Gohr, A.; Miret-Cuesta, M.; Goyeneche, L.; Rovira, Q.; Bogdanovic, O.; Bonnal, S.; Irimia, M.
10.1101/2020.11.25.397794 — developmental biology — Posted on 2020-11-27
439 The pluripotent stem cell-specific transcript ESRG is dispensable for human pluripotency
Takahashi, K.; Nakamura, M.; Narita, M.; Watanabe, A.; Ueda, M.; Takashima, Y.; Yamanaka, S.
10.1101/2020.11.25.397935 — cell biology — Posted on 2020-11-27
440 Non-invasive surveys of mammalian viruses using environmental DNA
Alfano, N.; Dayaram, A.; Axtner, J.; Tsangaras, K.; Kampmann, M.-L.; Mohamed, A.; Wong, S. T.; Gilbert, M. T. P.; Wilting, A.; Greenwood, A. D.
10.1101/2020.03.26.009993 — molecular biology — Posted on 2020-11-27
441 A systematic evaluation of IgM and IgG antibody assay accuracy in diagnosing acute Zika Virus infection in Brazil; lessons relevant to emerging infections
Medialdea-Carrera, R.; Lowen Levy Chalhoub, F.; Castanha, P.; Carvalho Sequeira, P.; Brasil, P.; Lewis Ximenez, L. L.; Turtle, L.; Solomon, T.; Bispo de Filippis, A. M.; Brown, D. W.; Griffiths, M.
10.1101/2020.11.25.399386 — microbiology — Posted on 2020-11-27
442 SCENITH: A flow cytometry based method to functionally profile energy metabolism with single cell resolution
ARGUELLO, R. J.; COMBES, A. J.; CHAR, R.; BOUSIQUOT, E.; GIGAN, J. P.; CAMOSSETO, V.; SAMAD, B.; TSUI, J.; YAN, P.; BOISSONNEAU, S.; FIGARELLA-BRANGER, D.; GATTI, E.; TABOURET, E.; Krummel, M. F.; PIERRE, P.
10.1101/2020.03.10.985796 — immunology — Posted on 2020-11-27
443 Microstructural underpinnings and macroscale functional implications of temporal lobe connectivity gradients
Vos de Wael, R.; Royer, J.; Tavakol, S.; Wang, Y.; Paquola, C.; Benkarim, O.; Eichert, N.; Lariviere, S.; Misic, B.; Smallwood, J.; Valk, S.; Bernhardt, B.
10.1101/2020.11.26.400382 — neuroscience — Posted on 2020-11-27
444 Enhanced virus detection and metagenomic sequencing in patients with meningitis and encephalitis
Piantadosi, A.; Mukerji, S. S.; Ye, S.; Leone, M. J.; Freimark, L.; Park, D. J.; Adams, G.; Lemieux, J.; Kanjilal, S.; Solomon, I. H.; Ahmed, A. A.; Goldstein, R.; Ganesh, V.; Ostrem, B.; Cummins, K. C.; Thon, J.; Kinsella, C. M.; Rosenberg, E. S.; Frosh, M. P.; Goldberg, M. B.; Cho, T.; Sabeti, P.
10.1101/2020.11.25.399394 — neuroscience — Posted on 2020-11-27
452 Mechanism and consequences of herpes simplex virus 1-mediated regulation of host mRNA alternative polyadenylation
Shi, Y.; Wang, X.; Liu, L.; Whisnant, A.; Hennig, T.; Djakovic, L.; Haque, N.; Bach, C.; Sandri-Goldin, R.; Erhard, F.; Friedel, C.; Dölken, L.
10.1101/2020.11.26.399626 — molecular biology — Posted on 2020-11-26
454 Multimodal imaging evidence for the brain basis of cognitive dysfunction in older HIV+ men
Fernandez Cruz, A. L.; Chen, C.-M.; Sanford, R.; Collins, D. L.; Brouillette, M.-J.; Mayo, N. E.; Fellows, L.
10.1101/2020.11.26.399592 — neuroscience — Posted on 2020-11-26
455 CHD8 haploinsufficiency alters the developmental trajectories of human excitatory and inhibitory neurons linking autism phenotypes with transient cellular defects
Villa, C. E.; Cheroni, C.; Lopez-Tobon, A.; Dotter, C.; Oliveira, B.; Sacco, R.; Yahya, A. C.; Morandell, J.; Gabriele, M.; Sommer, C.; Gabitto, M.; Testa, G.; Novarino, G.
10.1101/2020.11.26.399469 — neuroscience — Posted on 2020-11-26
456 Hippocampal Egr1-dependent neuronal ensemblesnegatively regulate motor learning
GIRALT, A.; Brito, V.; Montalban, E.; Pupak, A.; Masana, M.; Gines, S.; Alberch, J.; Martin, C.; Girault, J.-A.
10.1101/2020.11.26.399949 — neuroscience — Posted on 2020-11-26
457 A selective projection from the subthalamic nucleus to parvalbumin-expressing interneurons of the striatum
Kondabolu, K.; Doig, N. M.; Ayeko, O.; Kahn, B.; Torres, A.; Calvigioni, D.; Meletis, K.; Magill, P. J.; Koos, T.
10.1101/2020.11.26.400242 — neuroscience — Posted on 2020-11-26
458 The cerebellum is involved in internal and external speech error monitoring
Runnqvist, E.; Chanoine, V.; Strijkers, K.; Pattamadilok, C.; Bonnard, M.; Nazarian, B.; Sein, J.; Anton, J.-L.; Belin, P.; Alario, F.- X.
10.1101/2020.11.26.400317 — neuroscience — Posted on 2020-11-26
464 Direct Observation of the Mechanism of Antibiotic Resistance by Mix-and-Inject at the European XFEL
Pandey, S.; Calvey, G.; Katz, A. M.; Malla, T. N.; Koua, F.; Martin-Garcia, J.; Poudyal, I.; Yang, J.-H.; Vakili, M.; Yefanov, O.; Zielinski, K. A.; Bajt, S.; Awel, S.; Doerner, K.; Frank, M.; Gelisio, L.; Jernigan, R.; Kirkwood, H.; Kloos, M.; Koliyadu, J.; Mariani, V.; Miller, M. D.; Mills, G.; Nelson, G.; Olmos, J. L.; Sadri, A.; Sato, T.; Tolstikova, A.; Xu, W.; Ourmazd, A.; Spence, J. H. C.; Schwander, P.; Barty, A.; Chapman, H.; Fromme, P.; Mancuso, A.; Phillips, G.; Bean, R.; Pollack, L.; Schmidt, M.
10.1101/2020.11.24.396689 — biophysics — Posted on 2020-11-26
469 Host specialization in microparasites transmitted by generalist vectors: insights into the cellular and immunological mechanisms
Lin, Y.-P.; Tufts, D. M.; Dupuis, A. P.; Combs, M.; Marcinkiewicz, A. L.; Hirsbrunner, A. D.; Diaz, A. J.; Stout, J. L.; Blom, A. M.; Strle, K.; Davis, A. D.; Kramer, L. D.; Diuk-Wasser, M. A.
10.1101/2020.11.13.380550 — microbiology — Posted on 2020-11-26
471 CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Hosokawa, T.; Liu, P.-W.; Cai, Q.; Ferreira, J. S.; Levet, F.; Butler, C.; Sibarita, J.-B.; Choquet, D.; Groc, L.; Hosy, E.; Zhang, M.; Hayashi, Y.
10.1101/2020.11.25.397091 — neuroscience — Posted on 2020-11-26
473 Sub-millisecond conformational dynamics of the A2A adenosine receptor revealed by single-molecule FRET
Maslov, I.; Volkov, O.; Khorn, P.; Orekhov, P.; Gusach, A.; Kuzmichev, P.; Gerasimov, A.; Luginina, A.; Coucke, Q.; Bogorodskiy, A.; Gordeliy, V.; Wanninger, S.; Barth, A.; Hofkens, J.; Cherezov, V.; Gensch, T.; Hendrix, J.; Borshchevskiy, V.
10.1101/2020.11.26.400184 — biophysics — Posted on 2020-11-26
474 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2020-11-26
477 Genomic adaptations to an endolithic lifestyle in the coral-associated alga Ostreobium
Iha, C.; Dougan, K. E.; Varela, J. A.; Avila, V.; Jackson, C. J.; Bogaert, K. A.; Chen, Y.; Judd, L. M.; Wick, R. R.; Holt, K. E.; Pasella, M. M.; Ricci, F.; Repetti, S. I.; Medina, M.; Marcelino, V. R.; Chan, C. X.; Verbruggen, H.
10.1101/2020.07.21.211367 — genomics — Posted on 2020-11-26
479 Centromere drive and suppression by parallel pathways for recruiting microtubule destabilizers
Kumon, T.; Ma, J.; Stefanik, D.; Nordgren, E. C.; Akins, R. B.; Kim, J.; Levine, M. T.; Lampson, M.
10.1101/2020.11.26.400515 — evolutionary biology — Posted on 2020-11-26
481 A cell cycle kinase-phosphatase module restrains PI3K-Akt activity in an mTORC1-dependent manner
Sanz-Castillo, B.; Hurtado, B.; El Bakkali, A.; Hermida, D.; Salvador-Barbero, B.; Martinez-Alonso, D.; Gonzalez-Martinez, J.; Santiveri, C.; Campos-Oliva, R.; Ximenez, P.; Munoz, J.; Alvarez-Fernandez, M.; Malumbres, M.
10.1101/2020.11.26.399915 — cell biology — Posted on 2020-11-26
483 Gut microbiome composition predicts summer core range size in a generalist and specialist ungulate
Wolf, J. F.; Kriss, K. D.; MacAulay, K. M.; Munro, K.; Patterson, B. R.; Shafer, A. B. A.
10.1101/2020.08.04.236638 — molecular biology — Posted on 2020-11-26
485 An Optimised GAS-pharyngeal cell biofilm model
Vyas, H. K. N.; McArthur, J. D.; Sanderson-Smith, M. L.
10.1101/2020.11.25.399196 — microbiology — Posted on 2020-11-26
489 Combined inhibition of KDM6A/B and HDACs exacerbates integrated stress response and mediates therapeutic effects in IDH1-mutant glioma
Kayabolen, A.; Sahin, G. N.; Seker-Polat, F.; Cingoz, A.; Isik, B.; Acar, S.; Wakimoto, H.; Cahill, D. P.; Solaroglu, I.; Cribbs, A.; Oppermann, U.; Bagci-Onder, T.
10.1101/2020.11.26.400234 — cancer biology — Posted on 2020-11-26
490 Tumor irradiation combined with vascular-targeted photodynamic therapy enhances anti-tumor effects in preclinical prostate cancer.
Sjoberg, H. T.; Philippou, Y. J.; Magnussen, A. L.; Tullis, I. D.; Bridges, E.; Chatrian, A.; Loefebvre, J.; Tam, K. H.; Murphy, E. A.; Rittscher, J.; Preise, D.; Agemy, L.; Yechezkel, T.; Smart, S. C.; Kinchesh, P.; Gilchrist, S.; Allen, D. P.; Scheiblin, D. A.; Lockett, S. J.; Wink, D. A.; Lamb, A. D.; Mills, I. G.; Harris, A.; Muschel, R. J.; Vojnovic, B.; Scherz, A.; Hamdy, F. C.; Bryant, R. J.
10.1101/2020.11.26.400283 — cancer biology — Posted on 2020-11-26
493 An unexpected donor in the adaptive introgression candidate Helianthus annuus subsp. texanus.
Owens, G. L.; Todesco, M.; Bercovich, N.; Legare, J.-S.; Mitchell, N.; Whitney, K. D.; Rieseberg, L. H.
10.1101/2020.11.26.398933 — evolutionary biology — Posted on 2020-11-26
495 Archaeogenomics of a ~2,100-year-old Egyptian leaf provides a new timestamp on date palm domestication
Perez-Escobar, O. A.; Bellot, S.; Gros-Balthazard, M.; Flowers, J. M.; Nesbitt, M.; Ryan, P.; Gutaker, R. M.; Wells, T.; Schley, R. J.; Bogarin, D.; Przelomska, N.; Dodsworth, S.; Diaz, R.; Lehmann, M.; Petoe, P.; Eiserhardt, W.; Preick, M.; Hofreiter, M.; Hajdas, I.; Antonelli, A.; Leitch, I. J.; Gravendeel, B.; Torres, M. F.; Chomicki, G.; Renner, S. S.; PAPADOPULOS, A.; Purugganan, M.; Baker, W.
10.1101/2020.11.26.400408 — evolutionary biology — Posted on 2020-11-26
496 Drug and siRNA screens identify ROCK2 as a therapeutic target for ciliopathies.
Lake, A. V. R.; Smith, C. E. L.; Natarajan, S.; Basu, B.; Best, S. K.; Stevenson, T.; Trowbridge, R.; Grellscheid, S. N.; Bond, J.; Foster, R.; Johnson, C. A.
10.1101/2020.11.26.393801 — cell biology — Posted on 2020-11-26
499 Identification of fungal limonene-3-hydroxylases for biotechnological menthol production
Schempp, F. M.; Strobel, I.; Etschmann, M. M. W.; Bierwirth, E.; Panten, J.; Schewe, H.; Schrader, J.; Buchhaupt, M.
10.1101/2020.11.25.399378 — microbiology — Posted on 2020-11-26
501 Type VI secretion system killing by commensal Neisseria is influenced by the spatial dynamics of bacteria
Custodio, R.; Ford, R. M.; Ellison, C. J.; Liu, G.; Mickute, G.; Tang, C. M.; Exley, R. M.
10.1101/2020.11.26.400259 — microbiology — Posted on 2020-11-26
503 Digestion, fermentation, and pathogen anti-adhesive properties of the hMO-mimic di-fucosyl-β-cyclodextrin
Verkhnyatskaya, S. A.; Kong, C.; Klostermann, C.; Schols, H. A.; de Vos, P.; Walvoort, M. T. C.
10.1101/2020.11.26.399972 — microbiology — Posted on 2020-11-26
504 The intraflagellar transport protein IFT20 recruits ATG16L1 to early endosomes to promote autophagosome formation in T cells
Finetti, F.; Cassioli, C.; Cianfanelli, V.; Zevolini, F.; Onnis, A.; Gesualdo, M.; Brunetti, J.; Cecconi, F.; Baldari, C. T.
10.1101/2020.11.26.400135 — immunology — Posted on 2020-11-26
505 Phasic inhibition of dopamine neurons is an instrumental punisher
Peng, C. Y.; Jean Richard dit Bressel, P.; Gilchrist, S.; Power, J. M.; McNally, G.
10.1101/2020.11.25.399220 — neuroscience — Posted on 2020-11-26
507 Structural and biochemical analysis of OrfG: the VirB8-like component of the integrative and conjugative element ICESt3 from Streptococcus thermophilus
Cappele, J.; Mohamad-Ali, A.; Leblond-Bourget, N.; Mathiot, S.; Dhalleine, T.; Payot, S.; Savko, M.; Didierjean, C.; Favier, F.; Douzi, B.
10.1101/2020.11.26.395491 — biochemistry — Posted on 2020-11-26
508 Free-fatty acid receptor 4 inhibitory signaling in delta cells regulates islet hormone secretion in mice
Croze, M. L.; Flisher, M.; Guillaume, A.; Tremblay, C.; Noguchi, G. M.; Granziera, S.; Vivot, K.; Castillo, V. C.; Campbell, S. A.; Ghislain, J.; Huising, M. O.; Poitout, V.
10.1101/2020.07.17.208637 — physiology — Posted on 2020-11-26
510 The development of attentional control mechanisms in multisensory environments
Turoman, N.; Tivadar, R. I.; Retsa, C.; Maillard, A. M.; Scerif, G.; Matusz, P. J.
10.1101/2020.06.23.166975 — neuroscience — Posted on 2020-11-26
511 Pharmacologic profiling reveals lapatinib as a novel antiviral against SARS-CoV-2 in vitro
Raymonda, M. H.; Ciesla, J. H.; Monaghan, M.; Leach, J.; Asantewaa, G.; Smorodintsev-Schiller, L. A.; Lutz, M. M.; Schafer, X. L.; Takimoto, T.; Dewhurst, S.; Munger, J.; Harris, I. S.
10.1101/2020.11.25.398859 — microbiology — Posted on 2020-11-26
512 Host-directed FDA-approved drugs with antiviral activity against SARS-CoV-2 identified by hierarchical in silico/in vitro screening methods
Ginez, T.; Garaigorta, U.; Ramirez, D.; Castro, V.; Nozal, V.; Maestro, I.; Garcia-Carceles, J.; Campillo, N. E.; Martinez, A.; Gastaminza, P.; Gil, C.
10.1101/2020.11.26.399436 — microbiology — Posted on 2020-11-26
518 Accelerating Drug Discovery and Repurposingby Combining Transcriptional Signature Connectivity with Docking
Thorman, A. W.; Reigle, J.; Chutipongtanate, S.; Shamsaei, B.; Pilarczyk, M.; Fazel-Najafabadi, M.; Adamczak, R.; Kouril, M.; Morrow, A. L.; Czyzyk-Krzeska, M. F.; McCullumsmith, R.; Seibel, W.; Nassar, N.; Zheng, Y.; Hildeman, D.; Herr, A. B.; Medvedovic, M.; Meller, J.
10.1101/2020.11.25.399238 — bioinformatics — Posted on 2020-11-26
519 How ancient forest fragmentation and riparian connectivity generate high levels of genetic diversity in a micro-endemic Malagasy tree
Salmona, J.; Dresen, A.; Ranaivoson, A. E.; Manzi, S.; Le Pors, B.; Hong-Wa, C.; Razanatsoa, J.; Andriaholinirina, N. V.; Rasoloharijaona, S.; Vavitsara, M.-E.; Besnard, G.
10.1101/2020.11.25.394544 — genomics — Posted on 2020-11-26
522 A Synergistic Workspace for Human Consciousness Revealed by Integrated Information Decomposition
Luppi, A. I.; Mediano, P. A. M.; Rosas, F. E.; Allanson, J.; Pickard, J. D.; Carhart-Harris, R. L.; Williams, G. B.; Craig, M. M.; Finoia, P.; Owen, A. M.; Naci, L.; Menon, D. K.; Bor, D.; Stamatakis, E. A.
10.1101/2020.11.25.398081 — neuroscience — Posted on 2020-11-26
524 Cutting through the noise: reducing bias in motor adaptation analysis
Blustein, D.; Shehata, A.; Kuylenstierna, E.; Englehart, K.; Sensinger, J.
10.1101/2020.11.25.397992 — neuroscience — Posted on 2020-11-26
530 The mutational landscape of human somatic and germline cells
Moore, L.; Cagan, A.; Coorens, T.; Neville, M. D. C.; Sanghvi, R.; Sanders, M. A.; Oliver, T. R. W.; Leongamornlert, D.; Ellis, P.; Noorani, A.; Mitchell, T. J.; Butler, T. M.; Hooks, Y.; Warren, A. Y.; Jorgensen, M.; Dawson, K. J.; Menzies, A.; ONeill, L.; Latimer, C.; Teng, M.; VanBoxtel, R.; Iacobuzio-Donahue, C. A.; Martincorena, I.; Heer, R.; Campbell, P.; Fitzgerald, R. C.; Stratton, M.; Rahbari, R.
10.1101/2020.11.25.398172 — genomics — Posted on 2020-11-26
533 Automatic identification of bird females using egg phenotype
Sulc, M.; Hughes, A. E.; Troscianko, J.; Stetkova, G.; Prochazka, P.; Pozgayova, M.; Pialek, L.; Pialkova, R.; Brlik, V.; Honza, M.
10.1101/2020.11.25.398131 — ecology — Posted on 2020-11-26
534 QSM Reconstruction Challenge 2.0: Design and Report of Results
QSM Challenge 2.0 Organization Committee, ; Bilgic, B.; Langkammer, C.; Marques, J. P.; Meineke, J.; Milovic, C.; Schweser, F.
10.1101/2020.11.25.397695 — neuroscience — Posted on 2020-11-26
535 Differential impact of GABAA Receptors on Inhibitory connectivity for Superficial Pyramidal Neuron Responsiveness In Vivo
Tsai, Y.-C.; Hleihil, M.; Cramer, T.; Ferrari, K. D.; Barrett, M. J. P.; Bosshard, G.; Weber, B.; Stobart, J. L.; Tyagarajan, S. K.
10.1101/2020.11.25.397877 — neuroscience — Posted on 2020-11-26
536 3D segmentation of perivascular spaces on T1-weighted 3 Tesla MR images with a convolutional autoencoder and a U-shaped neural network
Boutinaud, P.; Tsuchida, A.; Laurent, A.; Adonias, F.; Hanifehlou, Z.; Nozais, V.; Verrecchia, V.; Lampe, L.; Zhang, J.; Zhu, Y.-C.; Tzourio, C.; Mazoyer, B.; Joliot, M.
10.1101/2020.11.25.397364 — neuroscience — Posted on 2020-11-26
538 Modelling optically pumped magnetometerinterference as a mean (magnetic) field
Tierney, T. M.; Alexander, N.; Mellor, S.; Holmes, N.; Seymour, R.; O'Neill, G. C.; Maguire, E. A.; Barnes, G. R.
10.1101/2020.11.25.397778 — neuroscience — Posted on 2020-11-26
539 The effect of ischaemic postconditioning on mucosal integrity and function in equine jejunal ischaemia
Verhaar, N.; Breves, G.; Hewicker-Trautwein, M.; Pfarrer, C.; Rohn, K.; Burmester, M.; Schnepel, N.; Neudeck, S.; Twele, L.; Kaestner, S.
10.1101/2020.11.25.397752 — pathology — Posted on 2020-11-26
549 Interpreting wide-band neural activity using convolutional neural networks
Frey, M.; Tanni, S.; Perrodin, C.; O'Leary, A.; Nau, M.; Kelly, J.; Banino, A.; Doeller, C. F.; Barry, C.
10.1101/871848 — neuroscience — Posted on 2020-11-26
552 An adaptive optics module for deep tissue multiphoton imaging in vivo
Rodriguez, C.; Chen, A.; Rivera, J. A.; Mohr, M. A.; Liang, Y.; Sun, W.; Milkie, D. E.; Bifano, T. G.; Chen, X.; Ji, N.
10.1101/2020.11.25.397968 — bioengineering — Posted on 2020-11-26
553 Deep learning-enhanced light-field imaging with continuous validation
Wagner, N.; Beuttenmueller, F.; Norlin, N.; Gierten, J.; Wittbrodt, J.; Weigert, M.; Hufnagel, L.; Prevedel, R.; Kreshuk, A.
10.1101/2020.07.30.228924 — bioengineering — Posted on 2020-11-26
554 Separation and Characterization of Endogenous Nucleosomes by Native Capillary Zone Electrophoresis - Top-Down Mass Spectrometry (nCZE-TDMS)
Jooss, K.; Schachner, L. F.; Watson, R.; Gillespie, Z. B.; Howard, S. A.; Cheek, M. A.; Meiners, M. J.; Licht, J. D.; Keogh, M.-C.; Kelleher, N. L.
10.1101/2020.11.25.398925 — biochemistry — Posted on 2020-11-26
557 Direct Observation of the Mechanism of Antibiotic Resistance by Mix-and-Inject at the European XFEL
Pandey, S.; Calvey, G.; Katz, A. M.; Malla, T. N.; Koua, F.; Martin-Garcia, J.; Poudyal, I.; Yang, J.-H.; Vakili, M.; Yefanov, O.; Zielinski, K. A.; Bajt, S.; Awel, S.; Doerner, K.; Frank, M.; Gelisio, L.; Jernigan, R.; Kirkwood, H.; Kloos, M.; Koliyadu, J.; Mariani, V.; Miller, M. D.; Mills, G.; Nelson, G.; Olmos, J. L.; Sadri, A.; Sato, T.; Tolstikova, A.; Xu, W.; Ourmazd, A.; Spence, J. H. C.; Schwander, P.; Barty, A.; Chapman, H.; Fromme, P.; Mancuso, A.; Phillips, G.; Bean, R.; Pollack, L.; Schmidt, M.
10.1101/2020.11.24.396689 — biophysics — Posted on 2020-11-26
559 PLD2-phosphatidic acid recruit ESCRT-I to late endosomes for exosome biogenesis.
Egea-Jimenez, A. L.; Audebert, S.; Castro-Cruz, M.; Borg, J.-P.; David, G.; Camoin, L.; Zimmermann, P.
10.1101/2020.11.25.398396 — cell biology — Posted on 2020-11-26
560 Massively parallel interrogation of protein fragment secretability using SECRiFY reveals features influencing secretory system transit
Boone, M.; Ramasamy, P.; Zuallaert, J.; Bouwmeester, R.; Van Moer, B.; Maddelein, D.; Turan, D.; Hulstraert, N.; Eeckhout, H.; Vandermarliere, E.; Martens, L.; Degroeve, S.; De Neve, W.; Vranken, W.; Callewaert, N.
10.1101/241349 — molecular biology — Posted on 2020-11-26
561 Selective BCL-XLAntagonists Eliminate Infected Cells from a Primary Cell Model of HIV Latency but not from Ex Vivo Reservoirs
Ren, Y.; huang, s. h.; Macedo, A.; Ward, A.; Conce, W.; Klevorn, T.; Leyre, L.; Chan, D.; Truong, R.; Rohwetter, T.; Zumbo, P.; Dundar, F.; Betel, D.; Kovacs, C.; Benko, E.; Bosque, A.; Jones, B.
10.1101/2020.11.25.397679 — microbiology — Posted on 2020-11-26
562 Comparative transcriptional profiling of the early host response to infection by typhoidal and non-typhoidal Salmonella serovars in human intestinal organoids
Abuaita, B. H.; Lawrence, A.-L. E.; Berger, R. P.; Hill, D. R.; Huang, S.; Yadagiri, V. K.; Bons, B.; Fields, C.; Wobus, C. E.; Spence, J. R.; Young, V. B.; O'Riordan, M.
10.1101/2020.11.25.397620 — microbiology — Posted on 2020-11-26
563 Integration in or Near Oncogenes Plays Only a Minor Role in Determining the in Vivo Distribution of HIV Integration Sites Before or During Suppressive Antiretroviral Therapy
Coffin, J. M.; Bale, M.; Wells, D.; Guo, S.; Luke, B.; Zerbato, J. M.; Sobolewski, M. D.; Sia, T.; Shao, W.; Wu, X.; Maldarelli, F.; Kearney, M. F.; Mellors, J. W.; Hughes, S. H.
10.1101/2020.11.25.397653 — microbiology — Posted on 2020-11-26
565 Rapid shift in microbial community structure in a neutral hydrothermal hot spring from Costa Rica
Rojas-Gätjens, D.; Arce-Rodriguez, A.; Puente-Sanchez, F.; Avendano, R.; Libby, E.; Conejo-Barboza, G.; Mora-Amador, R.; Rojas-Jimenez, K.; Pieper, D. H.; Chavarria, M.
10.1101/2020.11.23.395137 — microbiology — Posted on 2020-11-26
567 Bradyrhizobium diazoefficiens USDA110 nodulation of Aeschynomene afraspera is associated with atypical terminal bacteroid differentiation and suboptimal symbiotic efficiency
Nicoud, Q.; Lamouche, F.; Chaumeret, A.; Balliau, T.; Le Bars, R.; Bourge, M.; Pierre, F.; Guerard, F.; Sallet, E.; Tuffigo, S.; Pierre, O.; DESSAUX, Y.; Gilard, F.; Gakiere, B.; Nagy, I.; Kereszt, A.; Zivy, M.; Mergaert, P.; Gourion, B.; Alunni, B.
10.1101/2020.11.24.397182 — microbiology — Posted on 2020-11-26
570 The HSPG Syndecan is a core organizer of cholinergic synapses in C. elegans
Zhou, X.; Vachon, C.; Cizeron, M.; Romatif, O.; Buelow, H.; Jospin, M.; Bessereau, J.-L.
10.1101/2020.11.25.395806 — neuroscience — Posted on 2020-11-26
571 CaMKII activation triggers persistent formation and segregation of postsynaptic liquid phase
Hosokawa, T.; Liu, P.-W.; Cai, Q.; Ferreira, J. S.; Levet, F.; Butler, C.; Sibarita, J.-B.; Choquet, D.; Groc, L.; Hosy, E.; Zhang, M.; Hayashi, Y.
10.1101/2020.11.25.397091 — neuroscience — Posted on 2020-11-26
572 A Deep Graph Neural Network Architecture for Modelling Spatio-temporal Dynamics in resting-state functional MRI Data
Azevedo, T.; Campbell, A.; Romero-Garcia, R.; Passamonti, L.; Bethlehem, R. A. I.; Lio, P.; Toschi, N.
10.1101/2020.11.08.370288 — neuroscience — Posted on 2020-11-26
573 Intronic enhancer region governs transcript-specific BDNF expression in neurons
Tuvikene, J.; Esvald, E.-E.; Rähni, A.; Uustalu, K.; Zhuravskaya, A.; Avarlaid, A.; Makeyev, E. V.; Timmusk, T.
10.1101/2020.11.25.398156 — neuroscience — Posted on 2020-11-26
575 Rest functional brain maturation during the first year of life
Lemaitre, H.; Auge, P.; Saitovitch, A.; Vincon-Leite, A.; Tacchella, J.-M.; Fillon, L.; Calmon, R.; Dangouloff-Ros, V.; Levy, R.; Grevent, D.; Brunelle, F.; Boddaert, N.; Zilbovicius, M.
10.1101/760843 — neuroscience — Posted on 2020-11-26
577 ATP drives efficient terpene biosynthesis in marine thraustochytrids
Zhang, A.; Mernitz, K. A.; Wu, C.; Xiong, W.; He, Y.; Wang, G.; Wang, X.
10.1101/2020.11.20.391870 — systems biology — Posted on 2020-11-26
582 Chemical composition and insecticidal activity of Aeollanthus pubescens Benth leaf essential oil on the malaria vector Anopheles gambiae (Diptera: Culicidae).
Bohounton, R. B.; Djogbenou, L.; Djihinto, O. Y.; Dedome, O. S.-L.; Sovegnon, P. M.; Barea, B.; Adomou, A.; Villeneuve, P.; Tchobo, F. P.
10.1101/2020.11.25.397588 — pharmacology and toxicology — Posted on 2020-11-26
583 Fat Tissue Regulates the Pathogenesis and Severity of Cardiomyopathy in Murine Chagas Disease
Nagajyothi, J. F.; Lizardo, K.; Ayyappan, J. P.; Oswal, N.; Weiss, L. M.; Scherer, P. E.
10.1101/2020.11.25.397596 — pathology — Posted on 2020-11-26
584 RRM2 is a target for synthetic lethal interactions with replication stress checkpoint addiction in high-risk neuroblastoma
Nunes, C.; Depestel, L.; Mus, L. M.; Keller, K. M.; Delhaye, L.; Louwagie, A.; Rishfi, M.; Dolman, E. M.; Olexiouk, V.; Bartenhagen, C.; Devloed, F.; Sanders, E.; Eggermont, A.; Van Laere, J.; De Smet, E.; Van Loocke, W.; Morscio, J.; Loontiens, S.; Depuydt, P.; Decaesteker, B.; Tilleman, L.; Van Nieuwerburgh, F.; Deforce, D.; De Wilde, B.; Van Vlierberghe, P.; Vermeirssen, V.; Goossens, S.; Eyckerman, S.; Van Neste, C.; Roberts, S.; Fischer, M.; Molenaar, J. J.; Durinck, K.; Speleman, F.
10.1101/2020.11.25.397323 — cancer biology — Posted on 2020-11-26
587 Transient active osmotic swelling of epithelium upon curvature induction
Tomba, C.; Luchnikov, V.; Barberi, L.; Blanch-Mercader, C.; Roux, A.
10.1101/2020.11.25.398107 — biophysics — Posted on 2020-11-26
589 Direct information estimation from cryo-EM Movies with CARYON
Ramlaul, K.; Burt, A.; de Martin Garrido, N.; MacDonald, J.; Palmer, C.; Jakobi, A.; Aylett, C. H. S.
10.1101/2020.11.25.398891 — biophysics — Posted on 2020-11-26
590 AN EPILEPSY-CAUSING MUTATION LEADS TO CO-TRANSLATIONAL MISFOLDING
Urrutia, J.; Aguado, A.; Gomis-Perez, C.; Muguruza-Montero, A.; R. Ballesteros, O.; Zhang, J.; Nunez, E.; Malo, C.; Chung, H. J.; Leonardo, A.; Bergara, A.; Villarroel, A.
10.1101/2020.11.25.398222 — biophysics — Posted on 2020-11-26
591 How mu-Opioid Receptor Recognizes Fentanyl
Vo, Q. N.; Mahinthichaichan, P.; Shen, J.; Ellis, C. R.
10.1101/2020.08.16.253013 — biophysics — Posted on 2020-11-26
592 N-terminal VP1 truncations favor T=1 norovirus-like particles
Pogan, R.; Weiss, V. U.; Bond, K.; Duelfer, J.; Krisp, C.; Lyktey, N.; Mueller-Guhl, J.; Zorrato, S.; Allmaier, G.; Jarrold, M. F.; Munoz-Fontela, C.; Schlueter, H.; Uetrecht, C.
10.1101/2020.11.25.396499 — biophysics — Posted on 2020-11-26
595 Automated Segmentation of Fractured Distal Radii by 3D Geodesic Active Contouring of in vivo HR-pQCT Images
Ohs, N.; Collins, C. J.; Tourolle, D. C.; Atkins, P. R.; Schroeder, B.; Blauth, M.; Christen, P.; Müller, R.
10.1101/2020.10.14.339739 — bioengineering — Posted on 2020-11-26
596 Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U.; Karapetsas, A.; Nirujogi, R. S.; Mathea, S.; Pal, P.; Lis, P.; Taylor, M.; Purlyte, E.; Gourlay, R.; Dorward, M.; Weidlich, S.; Toth, R.; Polinski, N. K.; Knapp, S.; Tonelli, F.; Alessi, D. R.
10.1101/2020.11.25.397836 — biochemistry — Posted on 2020-11-26
597 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.
10.1101/2020.11.21.392803 — biochemistry — Posted on 2020-11-26
601 Common allotypes of ER aminopeptidase 1 have substrate-dependent and highly variable enzymatic properties
Jonathan, H. P.; Temponeras, I.; Kuiper, J.; Cortes, A.; Korczynska, J.; Kitchen, S.; Stratikos, E.
10.1101/2020.11.19.389403 — biochemistry — Posted on 2020-11-26
602 Extensive phylogenies of human development reveal variable embryonic patterns
Coorens, T. H. H.; Moore, L.; Robinson, P. S.; Sanghvi, R.; Christopher, J.; Hewinson, J.; Cagan, A.; Oliver, T.; Neville, M.; Hooks, Y.; Noorani, A.; Mitchell, T. J.; Fitzgerald, R.; Campbell, P.; Martincorena, I.; Rahbari, R.; Stratton, M.
10.1101/2020.11.25.397828 — genomics — Posted on 2020-11-26
603 Population genomics of the pathogenic yeast Candida tropicalis identifies hybrid isolates in environmental samples.
O'Brien, C. E.; Oliveira Pacheco, J. M.; O Cinneide, E.; Haase, M. A. B.; Hittinger, C. T.; Rogers, T. R.; Zaragoza, O.; Bond, U.; Butler, G.
10.1101/2020.11.25.397612 — genomics — Posted on 2020-11-26
608 Mediterranean Diet Reduces Monocyte Inflammatory Gene Expression and Influences Social Behavior in Nonhuman Primates
Johnson, C. S. C.; Shively, C. A.; Michalson, K. T.; Lea, A. J.; DeBo, R. J.; Howard, T. D.; Hawkins, G. A.; Appt, S. E.; Liu, Y.; McCall, C. E.; Herrington, D.; Register, T. C.; Snyder-Mackler, N.
10.1101/2020.01.27.917567 — genomics — Posted on 2020-11-26
611 Flexible multivariate linear mixed models for structured multiple traits
Kim, H.; Farage, G.; Lovell, J. T.; Mckay, J. K.; Juenger, T. E.; Sen, S.
10.1101/2020.03.27.012690 — genetics — Posted on 2020-11-26
612 DILS : Demographic Inferences with Linked Selection by using ABC
Fraisse, C.; Popovic, I.; Mazoyer, C.; Spataro, B.; Delmotte, S.; Romiguier, J.; Loire, E.; Simon, A.; Galtier, N.; Duret, L.; Bierne, N.; Vekemans, X.; Roux, C.
10.1101/2020.06.15.151597 — evolutionary biology — Posted on 2020-11-26
621 No Evidence for a Difference in 2D:4D Ratio between Youth with Elevated Prenatal Androgen Exposure due to Congenital Adrenal Hyperplasia and Controls
Nave, G.; Koppin, C. M.; Manfredi, D.; Richards, G.; Watson, S. J.; Geffner, M. E.; Yong, J. E.; Kim, R.; Ross, H. M.; Serrano-Gonzalez, M.; Kim, M. S.
10.1101/2020.05.07.082529 — developmental biology — Posted on 2020-11-26
623 Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
Rodermund, L.; Coker, H.; Oldenkamp, R.; Wei, G.; Bowness, J.; Rajkumar, B.; Nesterova, T. B.; Pinto, D.; Schermelleh, L.; Brockdorff, N.
10.1101/2020.11.24.396473 — developmental biology — Posted on 2020-11-26
625 Istaroxime treatment ameliorates calcium dysregulation in a zebrafish model for Phospholamban R14del cardiomyopathy
Kamel, S.; van Opbergen, C.; Koopman, L.; Verkerk, A.; Onderwater, Y.; Polidoro Pontalti, C.; Chocron, S.; Vos, M.; de Boer, T.; van Veen, T.; Bakkers, J.
10.1101/2020.11.25.397422 — cell biology — Posted on 2020-11-26
626 Early-life mitochondrial DNA damage results in lifelong deficits in energy production mediated by redox signaling in Caenorhabditis elegans
Rooney, J. P.; Hershberger, K. A.; Turner, E. A.; Donoghue, L. J.; Maurer, L. L.; Ryde, I. T.; Kim, J. J.; Joglekar, R.; Hibshman, J. D.; Smith, L. L.; Bhatt, D. P.; Ilkayeva, O. R.; Hirschey, M. D.; Meyer, J. N.
10.1101/2020.11.25.398164 — cell biology — Posted on 2020-11-26
627 Automated and customizable quantitative image analysis of whole C. elegans germlines
Toraason, E.; Adler, V. L.; Kurhanewicz, N. A.; DiNardo, A.; Saunders, A. M.; Cahoon, C. K.; Libuda, D. E.
10.1101/2020.11.25.398685 — cell biology — Posted on 2020-11-26
629 The 20S proteasome activator PA28γ controls the compaction of chromatin
Fesquet, D.; Lleres, D.; Grimaud, C.; Vigano, C.; Mechali, F.; Boulon, S.; Coux, O.; Bonne-Andrea, C.; Baldin, V.
10.1101/716332 — cell biology — Posted on 2020-11-26
630 Integrative Single-cell RNA-Seq and ATAC-Seq Analysis of Human Developmental Haematopoiesis
Ranzoni, A. M.; Tangherloni, A.; Berest, I.; Riva, S. G.; Myers, B.; Strzelecka, P. M.; Xu, J.; Panada, E.; Mohorianu, I.; Zaugg, J. B.; Cvejic, A.
10.1101/2020.05.06.080259 — cell biology — Posted on 2020-11-26
631 CtIP -mediated alternative mRNA splicing finetunes the DNA damage response
Prados-Carvajal, R.; Rodriguez-Real, G.; Gutierrez-Pozo, G.; Huertas, P.
10.1101/849547 — molecular biology — Posted on 2020-11-26
636 Local Field Potentials in a Pre-motor Region Predict Learned Vocal Sequences
Brown, D. E.; Chavez, J. I.; Nguyen, D. H.; Kadwory, A.; Voytek, B.; Arneodo, E.; Gentner, T. Q.; Gilja, V.
10.1101/2020.06.30.179861 — neuroscience — Posted on 2020-11-26
640 Evaluation and refinement of sample preparation methods for extracellular matrix proteome coverage
McCabe, M. C.; Schmitt, L. R.; Hill, R. C.; Dzieciatkowska, M.; Maslanka, M.; Daamen, W. F.; van Kuppevelt, T. H.; Hof, D. J.; Hansen, K. C.
10.1101/2020.11.25.391946 — biochemistry — Posted on 2020-11-25
643 Efficient GNE myopathy disease modeling with mutation specific phenotypes in human pluripotent stem cells by base editors
Park, J.-C.; Kim, J.; Jang, H.-K.; Lee, S.-Y.; Kim, K.-T.; Park, S.; Lee, H. S.; Choi, H.-J.; Park, S.-J.; Moon, S.-H.; Bae, S.; Cha, H.-J.
10.1101/2020.11.25.397711 — developmental biology — Posted on 2020-11-25
644 A developmentally programmed splicing failure attenuates the DNA damage response during mammalian zygotic genome activation
Waytt, C. D. R.; Pernaute, B.; Gohr, A.; Miret-Cuesta, M.; Goyeneche, L.; Rovira, Q.; Bogdanovic, O.; Bonnal, S.; Irimia, M.
10.1101/2020.11.25.397794 — developmental biology — Posted on 2020-11-25
646 The replicative amplification of MITEs and their impact on rice trait variability
Castanera, R.; Vendrell-Mir, P.; Bardil, A.; Carpentier, M. C.; Panaud, O.; Casacuberta, J.
10.1101/2020.10.01.322784 — molecular biology — Posted on 2020-11-25
647 Pupal cannibalism by worker honey bees contributes to the spread of Deformed wing virus.
Posada-Florez, F.; Lamas, Z. S.; Hawthorne, D. J.; Chen, Y.; Evans, J. D.; Ryabov, E. V.
10.1101/2020.11.25.396259 — microbiology — Posted on 2020-11-25
648 Selective transport of fluorescent proteins into the phage nucleus
Nguyen, K. T.; Sugie, J.; Khanna, K.; MacKennon, E. E.; Birkholz, E. A.; Lee, J.; Beierschmitt, C.; Villa, E.; Pogliano, J.
10.1101/2020.11.25.398438 — microbiology — Posted on 2020-11-25
649 Identification of RNAs bound by Hfq reveals widespread RNA partners and a sporulation regulator in the human pathogen Clostridioides difficile
Boudry, P.; Piattelli, E.; Drouineau, E.; Peltier, J.; Boutserin, A.; Lejars, M.; Hajnsdorf, E.; Monot, M.; Dupuy, B.; Martin-Verstraete, I.; Gautheret, D.; Toffano-Nioche, C.; SOUTOURINA, O.
10.1101/2020.11.25.398065 — microbiology — Posted on 2020-11-25
650 Regulatory roles of 5' UTR and ORF-internal RNAs detected by 3' end mapping
Adams, P. P.; Baniulyte, G.; Esnault, C.; Chegireddy, K.; Singh, N.; Monge, M.; Dale, R. K.; Storz, G.; Wade, J. T.
10.1101/2020.07.18.207399 — microbiology — Posted on 2020-11-25
652 mTORC1 and JUN are activated after deletion of Prohibitin 1 in Schwann cells and may link mitochondrial dysfunction to demyelination
Della-Flora Nunes, G.; Wilson, E. R.; Hurley, E.; He, B.; O'Malley, B. W.; Poitelon, Y.; Wrabetz, L.; Feltri, M. L.
10.1101/2020.11.25.398032 — neuroscience — Posted on 2020-11-25
653 Molecular and functional architecture of striatal dopamine release sites
Banerjee, A.; Imig, C.; Balakrishnan, K.; Kershberg, L.; Lipstein, N.; Uronen, R.-L.; Wang, J.; Cai, X.; Benseler, F.; Rhee, J. S.; Cooper, B. H.; Liu, C.; Wojcik, S. M.; Brose, N.; Kaeser, P. S.
10.1101/2020.11.25.398255 — neuroscience — Posted on 2020-11-25
655 The C99 domain of the amyloid precursor protein is a disordered membrane phase-preferring protein
Capone, R. F.; Tiwari, A.; Hadziselimovic, A.; Peskova, Y.; Hutchinson, J. M.; Sanders, C. R.; Kenworthy, A. K.
10.1101/2020.11.25.397893 — neuroscience — Posted on 2020-11-25
656 Brain Network Mechanisms of Visual Shape Completion
Keane, B. P.; Barch, D. M.; Mill, R. D.; Silverstein, S. M.; Krekelberg, B.; Cole, M. W.
10.1101/2020.08.03.233403 — neuroscience — Posted on 2020-11-25
657 Changes in epithelial proportions and transcriptional state underlie major premenopausal breast cancer risks
Murrow, L. M.; Weber, R. J.; Caruso, J.; McGinnis, C. S.; Phong, K.; Gascard, P.; Borowsky, A. D.; Desai, T. A.; Thomson, M.; Tlsty, T. D.; Gartner, Z. J.
10.1101/430611 — systems biology — Posted on 2020-11-25
659 Attitudes and Practices of Open Data, Preprinting, and Peer-review - a Cross Sectional Study on Croatian Scientists
Bazdaric, K.; Vrkic, I.; Arh, E.; Mavrinac, M.; Gligora Markovic, M.; Bilic-Zulle, L.; Stojanovski, J.; Malicki, M.
10.1101/2020.11.25.395376 — scientific communication and education — Posted on 2020-11-25
661 Silencing SmD1 in Solanaceae alters susceptibility to root-knot nematodes
Mejias, J.; Chen, Y.; Truong, N.-M.; Mulet, K.; Jaubert-Possamai, S.; Abad, P.; Favery, B.; Quentin, M.
10.1101/2020.11.25.398149 — plant biology — Posted on 2020-11-25
664 Structural basis for the association of PLEKHA7 with membrane-embedded phosphatidylinositol lipids
Aleshin, A. E.; Yao, Y.; Iftikar, A.; Bobkov, A. A.; Yu, J.; Cadwell, G.; Klein, M.; Dong, C.; Bankston, L. A.; Liddington, R. C.; Im, W.; Powis, G.; Marassi, F. M.
10.1101/2020.11.25.387084 — biochemistry — Posted on 2020-11-25
665 Comprehensive benchmarking of single cell RNA sequencing technologies for characterizing cellular perturbation
Verboom, K.; Assefa, A. T.; Yigit, N.; Anckaert, J.; Vandamme, N.; Rombaut, D.; Saeys, Y.; Thas, O.; Speleman, F.; Durinck, K.; Vandesompele, J.
10.1101/2020.11.25.396523 — molecular biology — Posted on 2020-11-25
668 Global analysis of protein-RNA interactions in SARS-CoV-2 infected cells reveals key regulators of infection
Kamel, W.; Noerenberg, M.; Cerikan, B.; Chen, H.; Järvelin, A. I.; Kammoun, M.; Lee, J.; Shuai, N.; Garcia-Moreno, M.; Andrejeva, A.; Deery, M. J.; Neufeldt, C. J.; Cortese, M.; Knight, M. L.; Lilley, K. S.; Martinez, J.; Davis, I.; Bartenschlager, R.; Mohammed, S.; Castello, A.
10.1101/2020.11.25.398008 — microbiology — Posted on 2020-11-25
669 Controlling membrane barrier during bacterial type-III protein secretion
Hüsing, S.; van Look, U.; Güse, A.; Galvez, E. J. C.; Charpentier, E.; Blair, D. F.; Erhardt, M.; Renault, T. T.
10.1101/2020.11.25.397760 — microbiology — Posted on 2020-11-25
670 3D8, a nucleic acid-hydrolyzing scFv, confers antiviral activity against SARS-CoV-2 and multiple coronaviruses in vitro
Lee, G.; Budhathoki, S.; Choi, H. S.; Oh, K.-j.; Lee, G.-Y.; Ham, Y. K.; Kim, Y. J.; Lim, Y. R.; Hoang, P. T.; Lee, Y.; Lim, S.-W.; Kim, J.-M.; Cho, S.; Song, J.-W.; Lee, S.; Kim, W.-K.
10.1101/2020.11.25.398909 — microbiology — Posted on 2020-11-25
671 A functional module states framework reveals cell states for drug and target prediction
Qin, G.; Knijnenburg, T.; Gibbs, D.; Moser, R.; Monnat, R. J.; Kemp, C.; Shmulevich, I.
10.1101/2020.11.24.394932 — systems biology — Posted on 2020-11-25
673 Overall patient's survival of glioblastoma associated to molecular markers: a pan-proteomic prospective study
Drelich, L.; Duhamel, M.; Wisztorski, M.; Aboulouard, S.; Gimeno, J.-p.; Caux, P.-d.; Ogrinc, N.; Devos, P.; Cardon, T.; Weller, M.; Escande, F.; Zairi, F.; Maurage, C.-A.; Fournier, I.; Le rhun, E.; Salzet, M.
10.1101/2020.11.24.397117 — cancer biology — Posted on 2020-11-25
675 phiC31 integrase for recombination mediated single copy insertion and genome manipulation in C. elegans
Yang, F.-J.; Chen, C.-N.; Chang, T.; Cheng, T.-W.; Chang, N.-C.; Kao, C.-Y.; Lee, C.-C.; Huang, Y.-C.; Chan, S.-P.; Wang, J.
10.1101/2020.11.25.398784 — genetics — Posted on 2020-11-25
678 A versatile human intestinal organoid-derived epithelial monolayer model for the study of enteric pathogens
Nickerson, K. P.; Llanos-Chea, A.; Ingano, L.; Serena, G.; Miranda-Ribera, A.; Perlman, M.; Lima, R.; Sztein, M. B.; Fasano, A.; Senger, S.; Faherty, C. S.
10.1101/2020.11.24.397141 — microbiology — Posted on 2020-11-25
680 Intracellular localisation of Mycobacterium tuberculosis affects antibiotic efficacy
Santucci, P.; Greenwood, D.; Fearns, A.; Chen, K.; Jiang, H.; Gutierrez, M. G.
10.1101/2020.11.25.398636 — microbiology — Posted on 2020-11-25
681 Th17 cells provide direct protective effects that limit stomach parasite burden following orogastric mucosal Trypanosoma cruzi infection
Cai, C. W.; Eickhoff, C. S.; Meza, K. A.; Blase, J. R.; Audette, R. E.; Chan, D. H.; Bockerstett, K. A.; DiPaolo, R. J.; Hoft, D. F.
10.1101/2020.11.24.397257 — immunology — Posted on 2020-11-25
682 RpoS Contributes to Successful Opportunistic Colonization by Human Enteric Pathogens during Plant Disease
Lovelace, A. H.; Lee, S.; Downs, D. M.; Soufi, Z.; Bota, P.; Preston, G. M.; Kvitko, B. H.
10.1101/2020.11.24.397208 — pathology — Posted on 2020-11-25
685 MIPMLP - Microbiome Pre-processing Machine Learning Pipeline.
Jasner, Y.; belogolovski, A.; Ben Izhak, M.; Koren, O.; Louzoun, Y.
10.1101/2020.11.24.397174 — microbiology — Posted on 2020-11-25
687 Specific norovirus interaction with Lewis x and Lewis a on human intestinal inflammatory mucosa during refractory inflammatory bowel disease
Tarris, G.; de Rougemont, A.; Estienney, M.; Charkaoui, M.; Mouillot, T.; Bonnotte, B.; Michiels, C.; Martin, L.; Belliot, G.
10.1101/2020.11.24.397125 — microbiology — Posted on 2020-11-25
688 Auxin requirements for a meristematic state in roots depend on a dual brassinosteroid function
Ackerman-Lavert, M.; Fridman, Y.; Matosevich, R.; Khandal, H.; Friedlander-Shani, L.; Vragovic, K.; Ben-El, R.; Horev, G.; Efroni, I.; Savaldi-Goldstein, S.
10.1101/2020.11.24.395483 — plant biology — Posted on 2020-11-25
690 Optimization of Spectral Library Size Improves DIA-MS Proteome Coverage
Ge, W.; Liang, X.; Zhang, F.; Xu, L.; Xiang, N.; Sun, R.; Liu, W.; Xue, Z.; Yi, X.; Wang, B.; Zhu, J.; Lu, C.; Zhan, X.; Chen, L.; Wu, Y.; Zheng, Z.; Gong, W.; Wu, Q.; Yu, J.; Ye, Z.; Teng, X.; Huang, S.; Zheng, S.; Liu, T.; Yuan, C.; Guo, T.
10.1101/2020.11.24.395426 — bioinformatics — Posted on 2020-11-25
691 Sparse Epistatic Regularization of Deep Neural Networks for Inferring Fitness Functions
Aghazadeh, A.; Nisonoff, H.; Ocal, O.; Huang, Y.; Koyluoglu, O. O.; Listgarten, J.; Ramchandran, K.
10.1101/2020.11.24.396994 — bioinformatics — Posted on 2020-11-25
692 A method to quantify autonomic nervous system function in healthy, able-bodied individuals
Debnath, S.; Levy, T. J.; Bellehsen, M.; Schwartz, R. M.; Barnaby, D. P.; Zanos, S.; Volpe, B. T.; Zanos, T. P.
10.1101/2020.11.24.396309 — bioengineering — Posted on 2020-11-25
693 Using seasonal genomic changes to understand historical adaptation: parallel selection on stickleback in highly-variable estuaries
Garcia-Elfring, A.; Paccard, A.; Thurman, T. J.; Wasserman, B. A.; Palkovacs, E. P.; Hendry, A. P.; Barrett, R. D.
10.1101/2020.11.24.396291 — genomics — Posted on 2020-11-25
696 SARS-CoV-2 utilizes a multipronged strategy to suppress host protein synthesis
Finkel, Y.; Gluck, A.; Winkler, R.; Nachshon, A.; Mizrahi, O.; Lubelsky, Y.; Zuckerman, B.; Slobodin, B.; Yahalom-Ronen, Y.; Tamir, H.; Ulitsky, I.; Israely, T.; Paran, N.; Schwartz, M.; Stern-Ginossar, N.
10.1101/2020.11.25.398578 — microbiology — Posted on 2020-11-25
697 COUNTEN an AI-driven tool for rapid, and objective structural analyses of the Enteric Nervous System
Kobayashi, Y.; Bukowski, A.; Das, S.; Espenel, C.; Gomez-Frittelli, J.; Wagle, N.; Bakhshi, S.; Saha, M.; Kaltschmidt, J. A.; Venkataraman, A.; Kulkarni, S.
10.1101/2020.11.24.396408 — neuroscience — Posted on 2020-11-25
700 Bile acid excess impairs thermogenic function in brown adipose tissue
Zhou, W.; VanDuyne, P.; Zhang, C.; Riessen, R.; Barragan, M.; Rowitz, B. M.; Teran-Garcia, M.; Boppart, S. A.; Anakk, S.
10.1101/2020.11.24.396895 — physiology — Posted on 2020-11-25
703 Learning epistatic polygenic phenotypes with Boolean interactions
Behr, M.; Kumbier, K.; Cordova-Palomera, A.; Aguirre, M.; Ashley, E.; Butte, A.; Arnaout, R.; Brown, J. B.; Preist, J.; Yu, B.
10.1101/2020.11.24.396846 — bioinformatics — Posted on 2020-11-25
704 ProCbA: Protein Function Prediction based on Clique Analysis
Khanteymoori, A.; Ghajehlo, M. B.; Behrouzinia, S.; Olyaee, M. H.
10.1101/2020.11.24.396432 — bioinformatics — Posted on 2020-11-25
707 Neuroskeletal effects of chronic bioelectric nerve stimulation in health and diabetes
Beeve, A. T.; Shen, I.; Zhang, X.; Magee, K.; Yan, Y.; MacEwan, M.; Scheller, E. L.
10.1101/2020.11.24.396143 — bioengineering — Posted on 2020-11-25
710 What are the demographic consequences of a seed bank stage for columnar cacti?
Arroyo-Cosultchi, G.; Mandujano, M. C.; Salguero-Gomez, R.; Martinez, A. J.; Golubov, J.
10.1101/2020.11.24.396374 — ecology — Posted on 2020-11-25
717 Sleep is required for odor exposure to consolidate memory and remodel olfactory synapses.
Munoz-Lobato, F.; Benedetti, K. L.; Farah, F.; Chandra, R.; Bokka, A.; Brueggemann, C.; Saifuddin, F. M.; Nordquist, S. K.; Li, J.; Chang, E.; Varshney, A.; Jiminez, V.; Andersen, K. E.; Baradwaj, A.; Miller, J. M.; Dunn, R. L.; Tsujimoto, B.; Duong, A.; Tran, A.; Churgin, M.; Fang-Yen, C.; Bremer, M.; Kato, S.; VanHoven, M.; L'Etoile, N.
10.1101/2020.11.24.395228 — neuroscience — Posted on 2020-11-25
720 distinct: a novel approach to differential distribution analyses
Tiberi, S.; Crowell, H. L.; Weber, L. M.; Samartsidis, P.; Robinson, M. D.
10.1101/2020.11.24.394213 — bioinformatics — Posted on 2020-11-25
722 Evolutionary analysis of SARS-CoV-2 spike protein for its different clades
Pereson, M. J.; Flichman, D.; Martinez, A.; Bare, P.; Garcia, G.; Di Lello, F.
10.1101/2020.11.24.396671 — evolutionary biology — Posted on 2020-11-25
724 SpheroidPicker: An Automated 3D cell culture manipulator robot using deep learning
Grexa, I.; Diosdi, A.; Kriston, A.; Moshkov, N.; Harmati, M.; Buzas, K.; Pietiainen, V.; Koos, K.; Hovath, P.
10.1101/2020.11.25.397331 — bioengineering — Posted on 2020-11-25
726 Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms
Malik, A. U.; Karapetsas, A.; Nirujogi, R. S.; Mathea, S.; Pal, P.; Lis, P.; Taylor, M.; Purlyte, E.; Gourlay, R.; Dorward, M.; Weidlich, S.; Toth, R.; Knapp, S.; Tonelli, F.; Alessi, D. R.
10.1101/2020.11.25.397836 — biochemistry — Posted on 2020-11-25
727 Revealing enzyme functional architecture via high-throughput microfluidic enzyme kinetics
Markin, C. J.; Mokhtari, D. A.; Sunden, F.; Appel, M. J.; Akiva, E.; Longwell, S.; Sabatti, C.; Herschlag, D.; Fordyce, P. M.
10.1101/2020.11.24.383182 — biochemistry — Posted on 2020-11-25
728 The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
Mueller, C.; Obermann, W.; Karl, N.; Wendel, H. G.; Taroncher-Oldenburg, G.; Pleschka, S.; Hartmann, R. K.; Gruenweller, A.; Ziebuhr, J.
10.1101/2020.11.24.389627 — molecular biology — Posted on 2020-11-25
730 Novel SARS-CoV-2 Whole-genome sequencing technique using Reverse Complement PCR enables easy, fast and accurate outbreak analysis in hospital and community settings
Wolters, F.; Coolen, J. P. M.; Tostmann, A.; van Groningen, L. F. J.; Bleeker-Rovers, C. P.; Tan, E. C. T. H.; van der Geest-Blankert, N.; Hautvast, J. L. A.; Hopman, J.; Wertheim, H. F. L.; Rahamat-Langendoen, J. C.; Storch, M.; Melchers, W. J. G.
10.1101/2020.10.29.360578 — microbiology — Posted on 2020-11-25
731 The structural connectome constrains fast brain dynamics
Sorrentino, P.; Seguin, C.; Rucco, R.; Liparoti, M.; Troisi Lopez, E.; Bonavita, S.; Quarantelli, M.; Sorrentino, G.; Jirsa, V.; Zalesky, A.
10.1101/2020.11.25.393017 — neuroscience — Posted on 2020-11-25
734 Rapid Detection of VanA/B-Producing Vancomycin-Resistant enterococci using Lateral Flow Immunoassay from colonies and blood culture
Oueslati, S.; VOLLAND, H.; Cattoir, V.; Bernabeu, S.; Girlich, D.; dulac, d.; Plaisance, M.; boutigny, l.; Dortet, L.; Simon, S.; Naas, T.
10.1101/2020.11.23.395293 — microbiology — Posted on 2020-11-25
735 Double Lock of a Potent Human Monoclonal Antibody against SARS-CoV-2
Wang, X.; Qin, C.; Wang, Y.; Rao, Z.; Xie, L.; Zhu, L.; Deng, Y.-Q.; Zhang, R.-r.; Cui, Z.; Sun, C.-Y.; Fan, C.-F.; Xing, X.; Huang, W.; Chen, Q.; Zhang, N.-N.; Ye, Q.; Cao, T.-S.; Wang, N.; Wang, L.; Cao, L.; Wang, H.; Kong, D.; Ma, J.; Luo, C.; Zhang, Y.; Nie, J.; Sun, Y.; Lv, Z.; Shaw, N.; Li, Q.; Li, X.-F.; Hu, J.
10.1101/2020.11.24.393629 — biophysics — Posted on 2020-11-25
736 Crystal structure of chloroplastic thioredoxin z defines a novel type-specific target recognition
Le Moigne, T.; Gurrieri, L.; Crozet, P.; Marchand, C. H.; Zaffagnini, M.; Sparla, F.; Lemaire, S. D.; Henri, J.
10.1101/2020.11.24.396572 — biochemistry — Posted on 2020-11-25
737 A Nasal Spray Solution of Grapefruit Seed Extract plus Xylitol Displays Virucidal Activity Against SARS-Cov-2 In Vitro
Ferrer, G. A.; Betancour, A.; Go, C. C.; Vazquez, H.; Westover, J. B.; Cagno, V.; Tapparel, C.; Sanchez-Gonzalez, M. A.
10.1101/2020.11.23.394114 — cell biology — Posted on 2020-11-25
738 Polymerization of misfolded protein lowers CX3CR1 expression in human PBMCs
Tumpara, S.; Ballmaier, M.; Wrenger, S.; König, M.; Lehmann, M.; Lichtinghagen, R.; Martinez-Delgado, B.; DeLuca, D.; Jedicke, N.; Welte, T.; Fromme, M.; Strnad, P.; Stolk, J.; Janciauskiene, S.
10.1101/2020.11.24.395640 — cell biology — Posted on 2020-11-25
740 The novel PII-interacting protein PirA regulates flux into the cyanobacterial ornithine-ammonia cycle
Bolay, P.; Muro-Pastor, I.; Rozbeh, R.; Timm, S.; Hagemann, M.; Florencio, F. J.; Forchhammer, K.; Klähn, S.
10.1101/2020.11.23.395327 — microbiology — Posted on 2020-11-25
741 Type I and III IFNs produced by the nasal epithelia and dimmed inflammation are key features of alpacas resolving MERS-CoV infection
Te, N.; Rodon, J.; Ballester, M.; Perez, M.; Pailler-Garcia, L.; Segales, J.; Vergara-Alert, J.; Bensaid, A.
10.1101/2020.11.23.395301 — immunology — Posted on 2020-11-25
742 Identification of QTL and Underlying Genes for Root System Architecture associated with Nitrate Nutrition in Hexaploid Wheat
Griffiths, M. D.; Atkinson, J. A.; Gardiner, L.-J.; Swarup, R.; Pound, M. P.; Wilson, M. H.; Bennett, M. J.; Wells, D. M.
10.1101/591529 — plant biology — Posted on 2020-11-25
743 First results on diversity patterns and selective sweeps in a Southeast European panel of maize inbred lines as combined with two West European panels
Galic, V.; Anđelkovic, V.; Kravic, N.; Grcic, N.; Ledencan, T.; Jambrovic, A.; Zdunic, Z.; Nicolas, S. D.; Charcosset, A.; Satovic, Z.; Simic, D.
10.1101/2020.11.24.376087 — genetics — Posted on 2020-11-25
744 Impacts of water quality on Acropora coral settlement: The relative importance of substrate quality and light
Ricardo, G. F.; Harper, C. E.; Negri, A. P.; Luter, H. M.; Abdul Wahab, M. A.; Jones, R. J.
10.1101/2020.11.19.390724 — ecology — Posted on 2020-11-25
746 Modeling pronoun resolution in the brain
Li, J.; Luh, W.-M.; Pylkkanen, L.; Yang, Y.; Hale, J.
10.1101/2020.11.24.396598 — neuroscience — Posted on 2020-11-25
749 Longitudinal white matter changes associated with cognitive training
Nichols, E. S.; Erez, J.; Stojanoski, B.; Lyons, K. M.; Witt, S. T.; Mace, C. A.; Khalid, S.; Owen, A. M.
10.1101/2020.11.24.396119 — neuroscience — Posted on 2020-11-25
761 Chromatin Fiber Folding Represses Transcription and Loop Extrusion in Quiescent Cells
Swygert, S. G.; Lin, D.; Portillo-Ledesma, S.; Lin, P.-Y.; Hunt, D. R.; Kao, C.-F.; Schlick, T.; Noble, W. S.; Tsukiyama, T.
10.1101/2020.11.24.396713 — molecular biology — Posted on 2020-11-24
763 Isolation and chacterisation of Klebsiella phages for phage therapy
Townsend, E.; Kelly, L.; Gannon, L.; Muscatt, G.; Dunstan, R.; Michniewski, S.; Sapkota, H.; Kiljunen, S. J.; Kolsi, A.; Skurnik, M.; Lithgow, T.; MIllard, A. D.; Jameson, E.
10.1101/2020.07.05.179689 — microbiology — Posted on 2020-11-24
764 Patterns of neural correlations in visual cortex vary with the number of objects
Jun, N. Y.; Ruff, D. A.; Kramer, L. E.; Bowes, B.; Tokdar, S. T.; Cohen, M. R.; Groh, J. M.
10.1101/777912 — neuroscience — Posted on 2020-11-24
772 ANGPTL4 from adipose, but not liver, is responsible for regulating plasma triglyceride partitioning
Spitler, K. M.; Shetty, S. K.; Cushing, E. M.; Sylvers-Davie, K. L.; Davies, B. S. J.
10.1101/2020.06.02.106815 — physiology — Posted on 2020-11-24
773 SUN-MKL1 crosstalk regulates nuclear deformation and fast motility of breast carcinoma cells in fibrillar ECM micro-environment
Sharma, V. P.; Williams, J.; Leung, E.; Sanders, J.; Eddy, R.; Castracane, J.; Oktay, M. H.; Entenberg, D.; Condeelis, J. S.
10.1101/2020.11.24.396390 — cancer biology — Posted on 2020-11-24
774 Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Bateman, N. W.; Tarney, C. M.; Abulez, T. S.; Hood, B. L.; Conrads, K. A.; Zhou, M.; Soltis, A. R.; Teng, P.-i.; Jackson, A.; Tian, C.; Dalgard, C. L.; Wilkerson, M. D.; Kessler, M. D.; Shriver, C. D.; Hu, H.; Cote, M.; Parker, G. J.; Segars, J.; Al-Hendy, A.; Risinger, J. R.; Darcy, K. M.; Casablanca, Y.; Maxwell, G. L.; Conrads, T. P.; O'Connor, T. D.
10.1101/2020.11.23.380337 — cancer biology — Posted on 2020-11-24
776 Genotype-free individual genome reconstruction of Multiparental Population Models by RNA sequencing data
Choi, K.; He, H.; Gatti, D. M.; Philip, V. M.; Raghupathy, N.; Gyuricza, I. G.; Munger, S. C.; Chesler, E. J.; Churchill, G. A.
10.1101/2020.10.11.335323 — bioinformatics — Posted on 2020-11-24
779 Transcriptome analysis of an albino mutant in Haworthia cooperi var. pilifera
Ren, M.; Zhang, Y.; Xu, H.; Zhu, Q.; Wang, Z.; Liu, S.; Li, P.; Liang, B.
10.1101/2020.11.24.396358 — genetics — Posted on 2020-11-24
780 Genomic Analyses of New Genes and Their Phenotypic Effects Reveal Rapid Evolution of Essential Functions in Drosophila Development
Xia, S.; VanKuren, N. W.; Chen, C.; Zhang, L.; Kemkemer, C.; Shao, Y.; Jia, H.; Lee, U.; Advani, A. S.; Gschwend, A.; Vibranovski, M.; Chen, S.; Zhang, Y. E.; Long, M.
10.1101/2020.10.27.357848 — evolutionary biology — Posted on 2020-11-24
782 Multispecies integrated population model reveals bottom-up dynamics in a seabird predator-prey system
Queroue, M.; Barbraud, C.; Barraquand, F.; Turek, D.; Delord, K.; Pacoureau, N.; Gimenez, O.
10.1101/2020.06.26.174250 — ecology — Posted on 2020-11-24
785 Structural basis of resistance to lincosamide, streptogramin A, and pleuromutilin antibiotics by ABCF ATPases in Gram-positive pathogens
Crowe-McAuliffe, C.; Murina, V.; Turnbull, K. J.; Kasari, M.; Mohamad, M.; Polte, C.; Takada, H.; Vaitkevicius, K.; Johansson, J.; Ignatova, Z.; Atkinson, G. C.; O'Neill, A. C.; Hauryliuk, V.; Wilson, D. N.
10.1101/2020.11.24.396648 — microbiology — Posted on 2020-11-24
786 Toxoplasma gondii serine hydrolases regulate parasite lipid mobilization during growth and replication within the host
Onguka, O.; Babin, B. M.; Lakemeyer, M.; Foe, I. T.; Amara, N.; Terrell, S. M.; Lum, K. M.; Cieplak, P.; Niphakis, M. J.; Long, J. Z.; Bogyo, M.
10.1101/2020.11.24.396663 — microbiology — Posted on 2020-11-24
790 Glycolic acid protects neurons against ischemia in vitro and in two animal models of stroke
Chovsepian, A.; Berchtold, D.; Winek, K.; Mamrak, U.; Ramirez-Alvarez, I.; Dening, Y.; Weitbrecht, L.; Dames, C.; Aillery, M.; Fernandez-Sanz, C.; Dieterich, M.; Falkai, P.; Plesnila, N.; Meisel, A.; Pan-Montojo, F. J.
10.1101/2020.11.24.396051 — neuroscience — Posted on 2020-11-24
791 Disease specific alterations in the olfactory mucosa of patients with Alzheimer's disease
Lampinen, R.; Fazaludeen, M. F.; Avesani, S.; Ord, T.; Penttila, E.; Lehtola, J.-M.; Saari, T.; Hannonen, S.; Saveleva, L.; Kaartinen, E.; Acosta, F. F.; Cruz-Haces, M.; Lopponen, H.; Mackay-Sim, A.; Malm, T.; Kaikkonen-Maatta, M.; Koivisto, A.; White, A. R.; Giugno, R.; Chew, S.; Kanninen, K. M.
10.1101/2020.11.24.395947 — neuroscience — Posted on 2020-11-24
795 Ovarian carcinosarcoma genomics and pre-clinical models highlight the N-MYC pathway as a key driver and susceptibility to EMT-targeting therapy
Ho, G. Y.; Kyran, E.; Bedo, J.; Wakefield, M.; Ennis, D.; Mirza, H.; Cooke, S.; Lieschke, E.; Vandenberg, C.; Kondrashova, O.; Upstill-Goddard, R.; Bailey, U.-M.; Biankin, S.; Roxburgh, P.; Glasspool, R.; Bryson, G.; Biankin, A.; Ratnayake, G.; McNally, O.; Traficante, N.; DeFazio, A.; Bowtell, D.; McNeish, I.; Papenfuss, A.; Scott, C.; Barker, H.
10.1101/2020.11.24.396796 — cancer biology — Posted on 2020-11-24
796 High-throughput phenotyping methods for quantifying hair fiber morphology
Lasisi, T.; Zaidi, A. A.; Webster, T. H.; Stephens, N. B.; Routch, K.; Jablonski, N. G.; Shriver, M. D.
10.1101/2020.11.24.392191 — bioinformatics — Posted on 2020-11-24
798 Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking
Schuller, M.; Correy, G. J.; Gahbauer, S.; Fearon, D.; Wu, T.; Diaz, R. E.; Young, I. D.; Carvalho Martins, L.; Smith, D. H.; Schulze-Gahmen, U.; Owens, T. W.; Deshpande, I.; Merz, G. E.; Thwin, A. C.; Biel, J. T.; Peters, J. K.; Moritz, M.; Herrera, N.; Kratochvil, H. T.; QCRG Structural Biology Consortium, ; Aimon, A.; Bennett, J. M.; Brandao Neto, J.; Cohen, A. E.; Dias, A.; Douangamath, A.; Dunnett, L.; Fedorov, O.; Ferla, M. P.; Fuchs, M.; Gorrie-Stone, T. J.; Holton, J. M.; Johnson, M. G.; Krojer, T.; Meigs, G.; Powell, A. J.; Rack, J. G. M.; Rangel, V. L.; Russi, S.; Skyner, R. E.; Smi
10.1101/2020.11.24.393405 — biochemistry — Posted on 2020-11-24
800 Copy number signatures predict chromothripsis and associate with poor clinical outcomes in patients with newly diagnosed multiple myeloma
Maclachlan, K.; Rustad, E. H.; Derkach, A.; Zheng-Lin, B.; Yellapantula, V.; Diamond, B.; Hultcrantz, M.; Ziccheddu, B.; Boyle, E.; Blaney, P.; Bolli, N.; Zhang, Y.; Dogan, A.; Lesohkin, A.; Morgan, G.; Landgren, O.; Maura, F.
10.1101/2020.11.24.395939 — genomics — Posted on 2020-11-24
805 Cassette recruitment in the chromosomal Integron of Vibrio cholerae
Vit, C.; Richard, E.; Fournes, F.; Whiteway, C.; Eyer, X.; Lapaillerie, D.; Parissi, V.; Mazel, D.; Loot, C.
10.1101/2020.11.24.395434 — molecular biology — Posted on 2020-11-24
806 The ESCRT-III machinery participates in the production of extracellular vesicles and protein export during Plasmodium falciparum infection
Avalos-Padilla, Y.; Georgiev, V. N.; Lantero, E.; Pujals, S.; Verhoef, R.; Borgheti-Cardoso, L. N.; Albertazzi, L.; Dimova, R.; Fernandez-Busquets, X.
10.1101/2020.11.24.395756 — microbiology — Posted on 2020-11-24
807 Robust expression of LINE-1 retrotransposon encoded proteins in oral squamous cell carcinoma
Mukherjee, K.; Sur, D.; Singh, A.; Rai, S.; Das, N. S.; Narindi, S.; Sekar, R.; Dhingra, V. K.; Jat, B.; Balraam, K. V. V.; Agarwal, S. P.; Mandal, P. K.
10.1101/2020.11.24.395285 — cancer biology — Posted on 2020-11-24
808 Entropy-driven translocation of disordered proteins through the Gram-positive bacterial cell wall
Halladin, D. K.; Ortega, F. E.; Ng, K. M.; Footer, M. J.; Mitic, N. S.; Malkov, S. N.; Gopinathan, A.; Huang, K. C.; Theriot, J. A.
10.1101/2020.11.24.396366 — biophysics — Posted on 2020-11-24
809 EoRNA, a barley gene and transcript abundance database.
Milne, L.; Bayer, M.; Rapazote-Flores, P.; Mayer, C.-D.; Waugh, R.; Simpson, C. G.
10.1101/2020.11.24.395749 — genomics — Posted on 2020-11-24
810 Heterochiasmy facilitated the establishment of gsdf as a novel sex determining gene in Atlantic halibut
Edvardsen, R. B.; Wallerman, O.; Furmanek, T.; Kleppe, L.; Jern, P.; Wallberg, A.; Kjaerner-Semb, E.; Maehle, S.; Olausson, S. K.; Sundstrom, E.; Harboe, T.; Mangor-Jensen, R.; Mogster, M.; Perrichon, P.; Norberg, B.; Rubin, C.-J.
10.1101/2020.11.24.396218 — genomics — Posted on 2020-11-24
811 Genomic evidence supports the introgression between two sympatric stickleback species inhabiting the White Sea basin
Nedoluzhko, A.; Sharko, F.; Tsygankova, S.; Boulygina, E.; Ibragimova, A.; Teslyuk, A.; Galindo-Villegas, J.; Rastorguev, S.
10.1101/2020.11.24.396010 — genomics — Posted on 2020-11-24
812 Increased Colonic Expression of ACE2 Associates with Poor Prognosis in Crohn's disease
Toyonaga, T.; Araba, K. C.; Kennedy, M. M.; Keith, B. P.; Wolber, E. A.; Beasley, C.; Steinbach, E. C.; Schaner, M. R.; Jain, A.; Long, M. D.; Barnes, E. L.; Herfarth, H. H.; Isaacs, K. L.; Hansen, J. J.; Kapadia, M.; Guillem, J. G.; Koruda, M. J.; Rahbar, R.; Sadiq, T.; Sethupathy, P.; Furey, T.; Ehre, C.; Sheikh, S.
10.1101/2020.11.24.396382 — genomics — Posted on 2020-11-24
813 First results on diversity patterns and selective sweeps in a Southeast European panel of maize inbred lines as combined with two West European panels
Galic, V.; Anđelkovic, V.; Kravic, N.; Grcic, N.; Ledencan, T.; Jambrovic, A.; Zdunic, Z.; Nicolas, S. D.; Charcosset, A.; Satovic, Z.; Simic, D.
10.1101/2020.11.24.376087 — genetics — Posted on 2020-11-24
814 Diverse natural variants suppress mutations in hundreds of essential genes
Parts, L.; Batte, A.; Lopes, M.; Yuen, M. W.; Laver, M.; San Luis, B.-J.; Yue, J.-X.; Pons, C.; Eray, E.; Aloy, P.; Liti, G.; van Leeuwen, J.
10.1101/2020.11.24.395855 — genetics — Posted on 2020-11-24
817 Time-resolved structured illumination microscopy reveals key principles of Xist RNA spreading
Brockdorff, N.; Rodermund, L.; Coker, H.; Oldenkamp, R.; Wei, G.; Bowness, J.; Rajkumar, B.; Nesterova, T. B.; Pinto, D.; Schermelleh, L.
10.1101/2020.11.24.396473 — developmental biology — Posted on 2020-11-24
819 Genetic dissection of the mitochondrial lipoylation pathway in yeast
Pietikainen, L. P.; Rahman, M. T.; Hiltunen, J. K.; Dieckmann, C. L.; Kastaniotis, A. J.
10.1101/2020.11.24.395780 — molecular biology — Posted on 2020-11-24
821 Expression of type I interferon-associated genes at antiretroviral therapy interruption predicts HIV virological rebound
Zacharopoulou, P.; Marchi, E.; Ogbe, A.; Robinson, N.; Brown, H.; Jones, M.; Parolini, L.; Pace, M.; Grayson, N.; Kaleebu, P.; Rees, H.; Fidler, S.; Goulder, P.; Klenerman, P.; Frater, J.
10.1101/2020.11.24.395574 — microbiology — Posted on 2020-11-24
824 Competition-based screening secures the evolutionary stability of a defensive microbiome
Worsley, S. F.; Innocent, T. M.; Holmes, N. A.; Al-Bassam, M. M.; Wilkinson, B.; Murrell, J. C.; Boomsma, J. J.; Yu, D. W.; Hutchings, M. I.
10.1101/2020.11.24.395384 — evolutionary biology — Posted on 2020-11-24
827 Stable neutralizing antibody levels six months after mild and severe COVID-19 episode
Pradenas, E.; Trinite, B.; Urrea, V.; Marfil, S.; Avila-Nieto, C.; Rodriguez de la Concepcion, M. L.; Tarres-Freixas, F.; Perez-Yanes, S.; Rovirosa, C.; Ainsua-Enrich, E.; Rodon, J.; Vergara-Alert, J.; Sagales, J.; Guallar, V.; Valencia, A.; Izquierdo-Useros, N.; Paredes, R.; Mateu, L.; Chamorro, A.; Massanella, M.; Carrillo, J.; Clotet, B.; Blanco, J.
10.1101/2020.11.22.389056 — immunology — Posted on 2020-11-24
828 Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines
Freischel, A. R.; Damaghi, M.; Cunningham, J. J.; Ibrahim-Hashim, A.; Gillies, R. J.; Gatenby, R. A.; Brown, J. S.
10.1101/2020.03.06.979518 — cancer biology — Posted on 2020-11-24
830 SEPIA: Simulation-based Evaluation of Prioritization Algorithms
Almaraz, K.; Jang, T.; Lewis, M.; Ngo, T.; Song, M.; Moshiri, N.
10.1101/2020.11.23.394890 — bioinformatics — Posted on 2020-11-24
832 Mutations in SARS-CoV-2 spike protein and RNA polymerase complex are associated with COVID-19 mortality risk
Hahn, G.; Wu, C. M.; Lee, S.; Hecker, J.; Lutz, S. M.; Haneuse, S.; Qiao, D.; Cho, M. H.; Randolph, A.; Laird, N. M.; Weiss, S. T.; Silverman, E. K.; Ribbeck, K.; Lange, C.
10.1101/2020.11.17.386714 — genomics — Posted on 2020-11-24
833 Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry
Taraskin, A.; Semenov, K.; Protasov, A.; Lozhkov, A.; Tyulin, A.; Shaldzhyan, A.; Ramsay, E.; Mirgorodskaya, O.; Klotchenko, S.; Zabrodskaya, Y.
10.1101/2020.11.23.394759 — molecular biology — Posted on 2020-11-24
834 The rocaglate CR-31-B (-) inhibits SARS-CoV-2 replication at non-cytotoxic, low nanomolar concentrations in vitro and ex vivo
Gruenweller, A.; Mueller, C.; Obermann, W.; Karl, N.; Wendel, H. G.; Taroncher-Oldenburg, G.; Pleschka, S.; Hartmann, R. K.; Ziebuhr, J.
10.1101/2020.11.24.389627 — molecular biology — Posted on 2020-11-24
836 Collateral Sensitivity Associated with Antibiotic Resistance Plasmids
Herencias, C.; Rodriguez-Beltran, J.; Leon-Sampedro, R.; Alonso-del Valle, A.; Palkovicova, J.; Canton, R.; San Millan, A.
10.1101/2020.07.10.198259 — microbiology — Posted on 2020-11-24
837 Insecticide resistance status of Aedes aegypti in Bangladesh
Al-Amin, H. M.; Johora, F. T.; Irish, S. R.; Hossainey, M. R. H.; Vizcaino, L.; Paul, K. K.; Khan, W. A.; Haque, R.; Alam, M. S.; Lenhart, A.
10.1101/2020.07.31.231076 — microbiology — Posted on 2020-11-24
838 A monoclonal antibody against staphylococcal enterotoxin B superantigen inhibits SARS-CoV-2 entry in vitro
Cheng, M. H.; Porritt, R. A.; Noval Rivas, M.; Krieger, J.; Ozdemir, A. B.; Garcia, G.; Arumugaswami, V.; Fries, B. C.; Arditi, M.; Bahar, I.
10.1101/2020.11.24.395079 — immunology — Posted on 2020-11-24
839 Locus coeruleus MRI contrast is associated with cortical thickness in older adults
Bachman, S. L.; Dahl, M. J.; Werkle-Bergner, M.; Duezel, S.; Forlim, C. G.; Lindenberger, U.; Kuehn, S.; Mather, M.
10.1101/2020.03.14.991596 — neuroscience — Posted on 2020-11-24
845 Timing the SARS-CoV-2 Index Case in Hubei Province
Pekar, J.; Worobey, M.; Moshiri, N.; Scheffler, K.; Wertheim, J. O.
10.1101/2020.11.20.392126 — evolutionary biology — Posted on 2020-11-24
846 Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
Prummel, K. D.; Crowell, H. L.; Nieuwenhuize, S.; Brombacher, E. C.; Daetwyler, S.; Soneson, C.; Kresoja-Rakic, J.; Ronner, M.; Kocere, A.; Ernst, A.; Labbaf, Z.; Clouthier, D. E.; Firulli, A. B.; Sanchez-Iranzo, H.; O'Rourke, R.; Raz, E.; Mercader, N.; Burger, A.; Felley-Bosco, E.; Huisken, J.; Robinson, M. D.; Mosimann, C.
10.1101/2020.11.11.355693 — developmental biology — Posted on 2020-11-24
850 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-24
854 Rapidly self-sterilizing PPE capable of 99% SARS-CoV-2 deactivation in 30seconds
Zinn, A. A.; Izadjoo, M.; Kim, H.; Kehn-Hall, K.; Lehman, C.; Brody, R. L.; Roth, R. R.; Vega, A.; Nguyen, K. K.; Ngo, N. T.; Zinn, H. T.; Panny, L.; Flor, R.; Antonopoulos, N.; Stoltenberg, R. M.
10.1101/2020.11.16.384040 — immunology — Posted on 2020-11-24
855 Extensive functional repertoire underpins complex behaviours: insights from Parkinson's disease
Sorrentino, P.; Rucco, R.; Baselice, F.; De Micco, R.; Tessitore, A.; Hillebrand, A.; Mandolesi, L.; Breakspear, M.; Gollo, L. L.; Sorrentino, G.
10.1101/823849 — neuroscience — Posted on 2020-11-24
856 The relationship between resting-state functional connectivity, antidepressant discontinuation and depression relapse
Berwian, I. M.; Wenzel, J. G.; Kuehn, L.; Schnuerer, I.; Kasper, L.; Veer, I. M.; Seifritz, E.; Stephan, K. E.; Walter, H.; Huys, Q. J. M.
10.1101/2020.02.06.937268 — neuroscience — Posted on 2020-11-24
858 Design of a Companion Bioinformatic Tool to detect the emergence and geographical distribution of SARS-CoV-2 Spike protein genetic variants
Massacci, A.; Sperandio, E.; D'Ambrosio, L.; Maffei, M.; Palombo, F.; Aurisicchio, L.; Ciliberto, G.; Pallocca, M.
10.1101/2020.06.22.133355 — bioinformatics — Posted on 2020-11-24
860 The methylomes of Lake Malawi cichlids reveal epigenetic variation associated with phenotypic diversification
Vernaz, G.; Malinsky, M.; Svardal, H.; Du, M.; Tyers, A. M.; Santos, M. E.; Durbin, R.; Genner, M. J.; Turner, G. F.; Miska, E. A.
10.1101/2020.11.24.383034 — evolutionary biology — Posted on 2020-11-24
865 Identifying genetic variants associated with cerebellar volume in 33,265 individuals from the UK-Biobank
Chambers, T.; Escott-Price, V.; Legge, S. E.; Baker, E.; Singh, K. D.; Walters, J. T.; Caseras, X.; Anney, R. J.
10.1101/2020.11.24.393249 — neuroscience — Posted on 2020-11-24
866 Memory Transfer of Random Time Patterns Across Modalities
Kang, H.; Auksztulewicz, R.; Chan, C. H.; Cappotto, D.; Rajendran, V. G.; Schnupp, J. W. H.
10.1101/2020.11.24.395368 — neuroscience — Posted on 2020-11-24
867 Lithium inhibits tryptophan catabolism via the inflammation-induced kynurenine pathway in human microglia
Goettert, R.; Fidzinski, P.; Kraus, L.; Schneider, U. C.; Holtkamp, M.; Endres, M.; Gertz, K.; Kronenberg, G.
10.1101/2020.11.24.388470 — neuroscience — Posted on 2020-11-24
869 The role of SOX9 in non-small cell lung cancer progression is histopathology-selective.
Verschuren, E. W.; Bao, J.; Närhi, K.; Teodosio, A.; Hemmes, A.; Linnavirta, N. M.; Mäyränpää, M. I.; Salmenkivi, K.; Le Quesne, J.
10.1101/2020.11.23.393926 — cancer biology — Posted on 2020-11-24
874 Reproducible abnormalities of functional gradient reliably predict clinical and cognitive symptoms in schizophrenia
Wang, M.; Li, A.; Liu, Y.; Yan, H.; Sun, Y.; Song, M.; Chen, J.; Chen, Y.; Wang, H.; Guo, H.; Wan, P.; Lv, L.; Yang, Y.; Li, P.; Lu, L.; Yan, J.; Wang, H.; Zhang, H.; Zhang, D.; Jiang, T.; Liu, B.
10.1101/2020.11.24.395251 — neuroscience — Posted on 2020-11-24
879 A comprehensive analysis of vomeronasal organ transcriptome reveals variable gene expression depending on age and function in rabbits
R Villamayor, P.; Robledo, D.; Fernandez, C.; Gullon, J.; Quintela, L.; Sanchez-Quinteiro, P.; Martinez, P.
10.1101/2020.11.24.395517 — genomics — Posted on 2020-11-24
880 Establishment of a highly efficient gene disruption strategy to analyze and manipulate lipid co-regulatory networks
Harayama, T.; Hashidate-Yoshida, T.; Aguilera-Romero, A.; Hamano, F.; Morimoto, R.; Shimizu, T.; Riezman, H.
10.1101/2020.11.24.395632 — genetics — Posted on 2020-11-24
881 CloneSeq: A Highly Sensitive Single-cell Analysis Platform for Comprehensive Characterization of Cells from 3D Culture
Bavli, D.; Sun, X.; Kozulin, C.; Ennis, D.; Motzik, A.; Biran, A.; Brielle, S.; Alajem, A.; Meshorer, E.; Buxboim, A.; Ram, O.
10.1101/2020.11.24.395541 — molecular biology — Posted on 2020-11-24
884 Insights into kinetics, release, and behavioral effects of brain-targeted hybrid nanoparticles forcholesterol delivery in Huntington disease
Birolini, G.; Valenza, M.; Ottonelli, I.; Passoni, A.; Favagrossa, M.; Duskey, J. T.; Bombaci, M.; Vandelli, M. A.; Colombo, L.; Bagnati, R.; Caccia, C.; Leoni, V.; Taroni, F.; Forni, F.; Ruozi, B.; Salmona, M.; Tosi, G.; Cattaneo, E.
10.1101/2020.11.24.395525 — neuroscience — Posted on 2020-11-24
885 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-24
887 The Physcomitrium (Physcomitrella) patens PpKAI2L receptors for strigolactones and related compounds highlight MAX2 dependent and independent pathways
LOPEZ-OBANDO, M.; GUILLORY, A.; BOYER, F.-D.; CORNU, D.; HOFFMANN, B.; LE BRIS, P.; POUVREAU, J.-B.; DELAVAULT, P.; RAMEAU, C.; DE SAINT GERMAIN, A.; BONHOMME, S.
10.1101/2020.11.24.395954 — plant biology — Posted on 2020-11-24
889 Crystal structure of prototype foamy virus (PFV) protease-reverse transcriptase fusion (PR-RT) reveals conformational plasticity: implications for function
Harrison, J. J. E. K.; Tuske, S.; Das, K.; Ruiz, F. X.; Bauman, J. D.; Boyer, P.; DeStefano, J. J.; Hughes, S. H.; Arnold, E.
10.1101/2020.11.23.395087 — biophysics — Posted on 2020-11-24
891 Critical Assessment of Protein Intrinsic Disorder Prediction
Necci, M.; Piovesan, D.; CAID Predictors, ; DisProt Curators, ; Tosatto, S. C. E.
10.1101/2020.08.11.245852 — bioinformatics — Posted on 2020-11-24
893 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E. S.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2020-11-24
894 Clonal dynamics in early human embryogenesis inferred from somatic mutation
Park, S.; Mali, N. M.; Kim, R.; Choi, J.-W.; Lee, J.; Lim, J.; Park, J. M.; Park, J. W.; Kim, D.; Kim, T.; Yi, K.; Choi, J. H.; Kwon, S. G.; Hong, J. H.; Youk, J.; An, Y.; Kim, S. Y.; Kim, M.; Kim, D. S.; Park, J. Y.; Oh, J. W.; Ju, Y. S.
10.1101/2020.11.23.395244 — genomics — Posted on 2020-11-24
897 The anti-inflammatory peptide Catestatin blocks chemotaxis
Muntjewerff, E. M.; Parv, K.; Mahata, S. K.; Phillipson, M.; Christoffersson, G.; van den Bogaart, G.
10.1101/2020.11.23.393934 — cell biology — Posted on 2020-11-24
900 Rapid shift in microbial community structure in a neutral hydrothermal hot spring from Costa Rica
Rojas-Gätjens, D.; Arce-Rodriguez, A.; Puente-Sanchez, F.; Avendano, R.; Libby, E.; Conejo-Barboza, G.; Mora-Amador, R.; Rojas-Jimenez, K.; Pieper, D. H.; Chavarria, M.
10.1101/2020.11.23.395137 — microbiology — Posted on 2020-11-24
902 The SC-SNc pathway boosts appetitive locomotion in predatory hunting
Huang, M.; Li, D.; Pei, Q.; Xie, z.; Gu, H.; Liu, A.; Chen, Z.; Wang, Y.; Sun, F.; Li, Y.; Zhang, J.; He, M.; Xie, Y.; Zhang, F.; Qi, X.; Shang, C.; Cao, P.
10.1101/2020.11.23.395004 — neuroscience — Posted on 2020-11-24
903 Predicting perturbation effects from resting state activity using functional causal flow
Nejatbakhsh, A.; Fumarola, F.; Esteki, S.; Toyoizumi, T.; Kiani, R.; Mazzucato, L.
10.1101/2020.11.23.394916 — neuroscience — Posted on 2020-11-24
908 PCK2 opposes mitochondrial respiration and maintains the redox balance in starved lung cancer cells
Leithner, K.; Grasmann, G.; Planque, M.; Madreiter-Sokolowski, C. T.; Hrzenjak, A.; Graier, W. F.; Fendt, S.-M.; Olschewski, H.
10.1101/2020.11.23.393686 — cancer biology — Posted on 2020-11-24
913 Visuomotor Activation of Inhibition-Processing in Pediatric Obsessive Compulsive Disorder: A Magnetoencephalography Study
Nishat, E.; Dockstader, C.; Wheeler, A. L.; Tan, T.; Anderson, J. A.; Mendlowitz, S.; Mabbott, D. J.; Arnold, P. D.; Ameis, S. H.
10.1101/2020.11.23.394841 — neuroscience — Posted on 2020-11-24
915 Membrane-tethered peptides derived from intracellular loops 2 and 3 of the urotensin II receptor act as allosteric biased ligands
Nassour, H.; Hoang, T. A.; Martin, R. D.; Dallagnol, J. C. C.; Billard, E.; Letourneau, M.; Novellino, E.; Carotenuto, A.; Allen, B. G.; Tanny, J. C.; Fournier, A.; Hebert, T. E.; Chatenet, D.
10.1101/2020.11.23.394270 — pharmacology and toxicology — Posted on 2020-11-24
918 Elevated cerebrospinal fluid cytokine levels in tuberculous meningitis predict survival in response to dexamethasone
Whitworth, L.; Troll, R.; Pagan, A. J.; Roca, F.; Edelstein, P. H.; Troll, M.; Tobin, D.; Phu, N. H.; Bang, N. D.; Thwaites, G.; Thuong Thuong, N. T.; Sewell, R.; Ramakrishnan, L.
10.1101/2020.11.23.394437 — immunology — Posted on 2020-11-24
919 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-11-24
921 Importin α2 association with chromatin: Direct DNA binding via a novel DNA binding domain
Jibiki, K.; Kodama, T.; Suenaga, A.; Kawase, Y.; Shibazaki, N.; Nomoto, S.; Nagasawa, S.; Nagashima, M.; Shimodan, S.; Kikuchi, R.; Okayasu, M.; Takashita, R.; Mehmood, R.; Saitoh, N.; Yoneda, Y.; Akagi, K.-i.; Yasuhara, N.
10.1101/2020.05.04.075580 — molecular biology — Posted on 2020-11-24
922 LayNii: A software suite for layer-fMRI. revision 1
Huber, L.; Poser, B. A.; Bandettini, P. A.; Arora, K.; Wagstyl, K.; Cho, S.; Goense, J.; Nothnagel, N.; Morgan, A. T.; Mueller, A. K.; van den Hurk, J.; Reynolds, R. C.; Glen, D. R.; Goebel, R. W.; Gulban, O. F.
10.1101/2020.06.12.148080 — neuroscience — Posted on 2020-11-24
924 Filtering Variables for Supervised Sparse Network Analysis
Towle-Miller, L. M.; Miecznikowski, J. C.; Zhang, F.; Tritchler, D. L.
10.1101/2020.03.12.985077 — bioinformatics — Posted on 2020-11-24
925 CBX1 variants cause a neurodevelopmental syndrome due to facultative heterochromatin dysfunction
Iwata-Otsubo, A.; Dias, K.-R.; Su, C.; Lindsay-Temple, S.; Zhu, Y.; Fiordaliso, S.; Ritter, A.; Baker, S. W.; Kuroda, Y.; Keena, B. A.; Grant, S. F.; Musuwadi Subramanian, G.; Zackai, E.; Edwards, M.; Evans, C.-A.; Dulik, M. C.; Buckley, M. F.; Roscioli, T.; Izumi, K.
10.1101/2020.09.29.319228 — genetics — Posted on 2020-11-24
926 Suboptimal intermediates underlie evolution of the Bicoid homeodomain
Onal, P.; Gunasinghe, H. I.; Umezawa, K. Y.; Zheng, M.; Ling, J.; Azeez, L.; Dalmeus, A.; Tazin, T.; Small, S.
10.1101/2020.08.20.257824 — evolutionary biology — Posted on 2020-11-24
934 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-24
935 Two Parallel Pathways Mediate Olfactory-Driven Backward Locomotion
Israel, S.; Rozenfeld, E.; Weber, D.; Huetteroth, W.; Parnas, M.
10.1101/2020.11.23.393819 — neuroscience — Posted on 2020-11-24
937 Phosphoproteomics identifies PI3K inhibitor-selective adaptive responses in pancreatic cancer cell therapy and resistance
Cintas, C.; Douche, T.; Dantes, Z.; Mouton-Barbosa, E.; Bousquet, M.-P.; Therville, N.; Pont, F.; Cayron, C.; Ramos-Delgado, F.; Thibault, B.; Garmy-Susini, B.; Cappello, P.; Burlet-Schiltz, O.; Hirsch, E.; Gomez-Brouchet, A.; Reichert, M.; Guillermet-Guibert, J.
10.1101/2020.10.08.313833 — cancer biology — Posted on 2020-11-24
938 Analysis of Biological Noise in an Organelle Size Control System
Bauer, D.; Ishikawa, H.; Wemmer, K.; Kondev, J.; Marshall, W. F.
10.1101/2020.08.31.276428 — biophysics — Posted on 2020-11-24
939 Statistical Integration of Two Omics Datasets Using GO2PLS
Gu, Z.; el Bouhaddani, S.; Pei, J.; Houwing-Duistermaat, J.; Uh, H.-W.
10.1101/2020.08.31.274175 — bioinformatics — Posted on 2020-11-24
945 Restructuring of genomic provinces of surface ocean plankton under climate change
Fremont, P.; Gehlen, M.; Vrac, M.; Leconte, J.; Wincker, P.; Iudicone, D.; Jaillon, O.
10.1101/2020.10.20.347237 — ecology — Posted on 2020-11-24
947 (p)ppGpp/GTP and malonyl-CoA modulate Staphylococcus aureus adaptation to FASII antibiotics and provide a basis for synergistic bi-therapy
Pathania, A.; Anba-Mondoloni, J.; Gominet, M.; Halpern, D.; Dairou, J.; Dupont, L.; Lamberet, G.; Trieu-Cuot, P.; Gloux, K.; Gruss, A.
10.1101/2020.03.26.007567 — microbiology — Posted on 2020-11-24
948 Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
Shibata, T.; Shah, S.; Evans, T.; Coleman, H. N.; Lieblong, B. J.; Spencer, H. J.; Quick, C. M.; Sasagawa, T.; Stephens, O. W.; Peterson, E.; Johann, D.; Lu, Y.-C.; Nakagawa, M.
10.1101/2020.11.07.364844 — immunology — Posted on 2020-11-24
949 Maximally selective single cell target for circuit control in epilepsy
Hadjiabadi, D. H.; Lovett-Barron, M.; Raikov, I.; Sparks, F.; Liao, Z.; Baraban, S. C.; Leskovec, J.; Losonczy, A.; Deisseroth, K.; Soltesz, I.
10.1101/2020.10.20.340364 — neuroscience — Posted on 2020-11-24
957 Evolutionary genetic integration of behavioural and endocrine components of the stress response
Houslay, T. M.; Earley, R. L.; White, S. J.; Lammers, W.; Grimmer, A. J.; Travers, L.; Johnson, E.; Young, A. J.; Wilson, A. J.
10.1101/770586 — evolutionary biology — Posted on 2020-11-23
958 Comparing statistical and mechanistic models to identify the drivers of mortality within a rear-edge beech population
Petit-Cailleux, C.; Davi, H.; Lefevre, F.; Garrigue, J.; Magdalou, J.-A.; Hurson, C.; Magnanou, E.; Muratorio, S.
10.1101/645747 — ecology — Posted on 2020-11-23
962 The mixed genetic origin of the first farmers of Europe
Marchi, N.; Winkelbach, L.; Schulz, I.; Brami, M.; Hofmanova, Z.; Blocher, J.; Reyna-Blanco, C. S.; Diekmann, Y.; Thiery, A.; Kapopoulou, A.; Link, V.; Piuz, V.; Kreutzer, S.; Figarska, S. M.; Ganiatsou, E.; Pukaj, A.; Karul, N.; Gerritsen, F.; Pechtl, J.; Peters, J.; Zeeb-Lanz, A.; Lenneis, E.; Teschler-Nicola, M.; Triantaphyllou, S.; Stefanovi, S.; Papageorgopoulou, C.; Wegmann, D.; Burger, J.; Excoffier, L.
10.1101/2020.11.23.394502 — evolutionary biology — Posted on 2020-11-23
963 Beyond fear centers: a distributed fMRI-based neuromarker for the subjective experience of fear
Zhou, F.; Zhao, W.; Qi, Z.; Geng, Y.; Yao, S.; Kendrick, K. M.; Wager, T. D.; Becker, B.
10.1101/2020.11.23.394973 — neuroscience — Posted on 2020-11-23
964 Peptide Ancestry Informative Markers in Uterine Neoplasms from Women of European, African and Asian Ancestry
Bateman, N. W.; Tarney, C.; Abulez, T.; Hood, B. L.; Conrads, K.; Zhou, M.; Soltis, A. R.; Teng, P.-i.; Jackson, A.; Tian, C.; Dalgard, C.; Wilkerson, M.; Kessler, M.; Shriver, C. D.; Hu, H.; Cote, M.; Parker, G. J.; Segars, J.; Al-Hendy, A.; Risinger, J.; Darcy, K.; Casablanca, Y.; George, M. L.; Conrads, T. P.; O'Connor, T. D.
10.1101/2020.11.23.380337 — cancer biology — Posted on 2020-11-23
965 In-Silico analysis reveals lower transcription efficiency of C241T variant of SARS-CoV-2 with host replication factors MADP1 and hnRNP-1
Chaudhari, A.; Chaudhari, M.; Mahera, S.; Saiyed, Z.; Nathani, N.; Shukla, S.; Patel, C.; Patel, D.; Joshi, M.; Joshi, C.
10.1101/2020.11.22.393009 — bioinformatics — Posted on 2020-11-23
966 find-tfbs: a tool to identify functional non-coding variants associated with complex human traits using open chromatin maps and phased whole-genome sequences
Meric de Bellefon, S.; Thibord, F.; Auer, P. L.; Blangero, J.; Coban-Akdemir, Z. H.; Floyd, J. S.; Fornage, M.; Johnsen, J. M.; Lange, L. A.; Lewis, J. P.; Mathias, R. A.; McHugh, C. P.; Moon, J.-Y.; Reiner, A. P.; Stilp, A. M.; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, ; Lettre, G.
10.1101/2020.11.23.394296 — genomics — Posted on 2020-11-23
967 HPRep: Quantifying reproducibility in HiChIP and PLAC-seq datasets
Rosen, J. D.; Yang, Y.; Abnousi, A.; Chen, J.; Song, M.; Jones, I. R.; Shen, Y.; Hu, M.; Li, Y.
10.1101/2020.11.23.394239 — genomics — Posted on 2020-11-23
968 DNA barcodes and reliable molecular identifications in a diverse group of invasive pests: lessons from Bactrocera fruit flies on variation across the COI gene, introgression, and standardization
Doorenweerd, C.; San Jose, M.; Leblanc, L.; Barr, N.; Geib, S.; Chung, A. Y. C.; Dupuis, J.; Ekayanti, A.; Fiegalan, E.; Hemachandra, K. S.; Hossain, M. A.; Huang, C.-L.; Hsu, Y.-F.; Morris, K. Y.; Maryani Mustapeng, A.; Niogret, J.; Hong Pham, T.; Sirisena, U. G. A. I.; Rubinoff, D.
10.1101/2020.11.23.394510 — evolutionary biology — Posted on 2020-11-23
971 Challenges for targeting SARS-CoV-2 proteases as a therapeutic strategy for COVID-19
Steuten, K.; Kim, H.; Widen, J. C.; Babin, B. M.; Onguka, O.; Lovell, S.; Bolgi, O.; Cerikan, B.; Cortese, M.; Muir, R. K.; Bennett, J. M.; Geiss-Friedlander, R.; Peters, C.; Bartenschlager, R.; Bogyo, M.
10.1101/2020.11.21.392753 — microbiology — Posted on 2020-11-23
972 Response to thermal and infection stresses in an American vector of visceral leishmaniasis.
Martins, K. A.; Moraes, C. S.; Broughton, S. J.; Lazzari, C. R.; Bates, P. A.; Pereira, M. H.; Dillon, R. J.
10.1101/2020.11.23.373100 — microbiology — Posted on 2020-11-23
973 Stable neutralizing antibody levels six months after mild and severe COVID-19 episode
Pradenas, E.; Trinite, B.; Urrea, V.; Marfil, S.; Avila-Nieto, C.; Rodriguez de la Concepcion, M. L.; Tarres-Freixas, F.; Perez-Yanes, S.; Rovirosa, C.; Ainsua-Enrich, E.; Rodon, J.; Vergara-Alert, J.; Sagales, J.; Guallar, V.; Valencia, A.; Izquierdo-Useros, N.; Paredes, R.; Mateu, L.; Chamorro, A.; Massanella, M.; Carrillo, J.; Clotet, B.; Blanco, J.
10.1101/2020.11.22.389056 — immunology — Posted on 2020-11-23
975 Neural signatures of predictive language processing in Parkinson's disease with and without mild cognitive impairment
Leon-Cabrera, P.; Pagonabarraga, J.; Moris, J.; Martinez-Horta, S.; Marin-Lahoz, J.; Horta-Barba, A.; Bejr-Kasem, H.; Kulisevsky, J.; Rodriguez-Fornells, A.
10.1101/2020.11.23.392647 — neuroscience — Posted on 2020-11-23
978 A Synthetic Defective Interfering SARS-CoV-2
Yao, S.; Narayanan, A.; Majowicz, S.; Jose, J.; Archetti, M.
10.1101/2020.11.22.393587 — synthetic biology — Posted on 2020-11-23
979 The multidisciplinary nature of COVID-19 research
Arencibia-Jorge, R.; Garcia-Garcia, L.; Galban-Rodriguez, E.; Carrillo-Calvet, H.
10.1101/2020.11.23.394312 — scientific communication and education — Posted on 2020-11-23
980 Obesity-Activated Lung Stomal Cells Promote Myeloid-Lineage Cell Accumulation and Breast Cancer Metastasis
Hillers-Ziemer, L. E.; Williams, A. E.; Janquart, A.; Grogan, C.; Thompson, V.; Sanchez, A.; Arendt, L. M.
10.1101/2020.11.23.394387 — cancer biology — Posted on 2020-11-23
986 A repurposed, blood gene signature is associated with poor outcomes in SARS-CoV-2
Juan-Guardela, B. M.; Sun, J.; Zhang, T.; Xu, B.; Michaud, G.; Herazo-Maya, J. D.
10.1101/2020.11.21.392670 — genomics — Posted on 2020-11-23
989 Quench me if you can: Alpha-2-macroglobulin trypsin complexes enable serum biomarker analysis by MALDI mass spectrometry
Taraskin, A.; Semenov, K.; Protasov, A.; Lozhkov, A.; Tyulin, A.; Shaldzhyan, A.; Ramsay, E.; Mirgorodskaya, O.; Klotchenko, S.; Zabrodskaya, Y.
10.1101/2020.11.23.394759 — molecular biology — Posted on 2020-11-23
991 Enteric glial cells respond to a dietary change in the lamina propria in a MyD88-dependent manner
Liu, Z.; Sun, H.; Liang, M.; Gao, J.; Meng, L.; Zheng, X.; Wei, Y.; Kou, Y.; Wang, Y.
10.1101/2020.11.23.394601 — neuroscience — Posted on 2020-11-23
993 Interactions of anti-COVID-19 drug candidates with multispecific ABC and OATP drug transporters
Telbisz, A.; Ambrus, C.; Mozner, O.; Szabo, E.; Varady, G.; Bakos, E.; Sarkadi, B.; Ozvegy-Laczka, C.
10.1101/2020.11.21.392555 — pharmacology and toxicology — Posted on 2020-11-23
995 Metabolic differentiation of co-occurring Accumulibacter clades revealed through genome-resolved metatranscriptomics
McDaniel, E. A.; Moya-Flores, F.; Keene Beach, N.; Camejo, P. Y.; Oyserman, B. O.; Kizaric, M.; Khor, E. H.; Noguera, D. R.; McMahon, K. D.
10.1101/2020.11.23.394700 — genomics — Posted on 2020-11-23
997 SAICAr-dependent and independent effects of ADSL deficiency on neurodevelopment
Dutto, I.; Gerhards, J.; Herrera, A.; Junza, A.; Yanes, O.; Boeckx, C.; Burkhalter, M. D.; Pons, S.; Philipp, M.; Luders, J.; Stracker, T. H.
10.1101/2020.11.23.394767 — developmental biology — Posted on 2020-11-23
1000 The impact of multifactorial stress combination on plant growth and survival
Zandalinas, S. I.; Sengupta, S.; Fritschi, F. B.; Azad, R.; Nechushtai, R.; Mittler, R.
10.1101/2020.11.23.394593 — plant biology — Posted on 2020-11-23
1001 SCReadCounts: Estimation of cell-level SNVs from scRNA-seq data
Prashant, N.; Alomran, N.; Chen, Y.; Liu, H.; Bousounis, P.; Movassagh, M.; Edwards, N. J.; Horvath, A.
10.1101/2020.11.23.394569 — bioinformatics — Posted on 2020-11-23
1003 Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences.
Zhang, X.; Harding, B.; Aggad, D.; Courtine, D.; Chen, J.-X.; Pujol, N.; Ewbank, J.
10.1101/2020.11.23.391201 — microbiology — Posted on 2020-11-23
1005 Pulmonary B cells ameliorate Alzheimer's disease-like neuropathology
Feng, W.; Zhang, Y.; Wang, T.; Wang, Z.; Chen, Y.; Sheng, C.; Zou, Y.; Pang, Y.; Gao, J.; Zhang, Y.; Shi, J.; Li, Q.; Xiao, M.
10.1101/2020.11.23.393942 — neuroscience — Posted on 2020-11-23
1007 Household-Level Risk Factors for Aedes aegypti Pupal Density in Guayaquil, Ecuador
Ha, T.-A.; Leon, T. M.; Lalangui, K.; Ponce, P.; Marshall, J. M.; Cevallos, V.
10.1101/2020.11.23.391938 — ecology — Posted on 2020-11-23
1009 Satb2 acts as a gatekeeper for major developmental transitions during early vertebrate embryogenesis
Pradhan, S. J.; reddy, p. c.; Smutny, M.; Sharma, A.; Sako, K.; Oak, M. S.; Shah, R.; Pal, M.; Deshpande, O.; Tang, Y.; Mishra, R. K.; Deshpande, G.; Giraldez, A.; Sonawane, M.; Heisenberg, C.-P.; Galande, S.
10.1101/2020.11.23.394171 — developmental biology — Posted on 2020-11-23
1010 Asymmetric requirement of Dpp/BMP morphogen dispersal in the Drosophila wing disc
Matsuda, S.; Schaefer, J. V.; Mii, Y.; Hori, Y.; Bieli, D.; Taira, M.; Plueckthun, A.; Affolter, M.
10.1101/2020.11.23.394379 — developmental biology — Posted on 2020-11-23
1011 Bone marrow stromal cell transplantation ameliorates cytopenia caused by depletion FAP-α expressing cells.
Camarillo, E.; Watson, L.; Loftus, P.; Alagesan, S.; O'Donoghue, Y.; Deedigan, L. M.; O'Flynn, L.; Barkley, L. R.; Elliman, S. J.
10.1101/2020.11.23.393959 — cell biology — Posted on 2020-11-23
1013 The Drosophila Baramicin polypeptide gene protects against fungal infection
Hanson, M. A.; Cohen, L. B.; Marra, A.; Iatsenko, I.; Wasserman, S. A.; Lemaitre, B.
10.1101/2020.11.23.394148 — immunology — Posted on 2020-11-23
1014 A novel, ataxic mouse model of Ataxia Telangiectasia caused by a clinically relevant nonsense mutation
Perez, H.; Abdallah, M. F.; Chavira, J. I.; Egeland, M. T.; Vo, K. L.; Sanghez, V.; Buechsenschuetz, C. L.; Kim, J. L.; Pind, M.; Nakamura, K.; Hicks, G. G.; Gatti, R. A.; Madrenas, J.; Iacovino, M.; McKinnon, P.; Mathews, P. J.
10.1101/2020.11.23.394098 — neuroscience — Posted on 2020-11-23
1015 Two Parallel Pathways Mediate Olfactory-Driven Backward Locomotion
Israel, S.; Rozenfeld, E.; Weber, D.; Huetteroth, W.; Parnas, M.
10.1101/2020.11.23.393819 — neuroscience — Posted on 2020-11-23
1017 Different RNA profiles in plasma derived small and large extracellular vesicles of Neurodegenerative diseases patients.
Sproviero, D.; Gagliardi, S.; Zucca, S.; Arigoni, M.; Giannini, M.; Garofalo, M.; Olivero, M.; Dell'Orco, M.; Pansarasa, O.; Bernuzzi, S.; Avenali, M.; Cotta Ramusino, M.; Diamanti, L.; Minafra, B.; Perini, G.; Zangaglia, R.; Costa, A.; Ceroni, M.; Perrone-Bizzozero, N. I.; Cereda, C.
10.1101/2020.11.23.390591 — neuroscience — Posted on 2020-11-23
1018 Building a virtual summer research experience in cancer for high school and early undergraduate students: lessons from the COVID-19 pandemic
Corson, T. W.; Hawkins, S. M.; Sanders, E.; Byram, J.; Cruz, L.-A.; Olson, J.; Speidell, E.; Schnabel, R.; Balaji, A.; Ogbeide, O.; Dinh, J.; Hinshaw, A.; Cummings, L.; Bonds, V.; Nakshatri, H.
10.1101/2020.11.23.393967 — scientific communication and education — Posted on 2020-11-23
1019 Local brassinosteroid biosynthesis enables optimal root growth
Vukasinovic, N.; Wang, Y.; Vanhoutte, I.; Fendrych, M.; Guo, B.; Kvasnica, M.; Jiroutova, P.; Oklestkova, J.; Strnad, M.; Russinova, E.
10.1101/2020.11.23.391474 — plant biology — Posted on 2020-11-23
1021 Cocaine receptor identified as BASP1
Harraz, M. M.; Malla, A. P.; Semenza, E. R.; Shishikura, M.; Hwang, Y.; Kang, I. G.; Song, Y. J.; Snowman, A. M.; Cortes, P.; Snyder, S. H.
10.1101/2020.11.23.392787 — pharmacology and toxicology — Posted on 2020-11-23
1025 Cross-validation of distance measurements in proteins by PELDOR/DEER and single-molecule FRET
Peter, M. F.; Gebhardt, C.; Maechtel, R.; Glaenzer, J.; Thomas, G. H.; Cordes, T.; Hageluecken, G.
10.1101/2020.11.23.394080 — biophysics — Posted on 2020-11-23
1027 Maximizing statistical power to detect clinically associated cell states with scPOST
Millard, N.; Korsunsky, I.; Weinand, K.; Fonseka, C. Y.; Nathan, A.; Kang, J. B.; Raychaudhuri, S.
10.1101/2020.11.23.390682 — bioinformatics — Posted on 2020-11-23
1031 Fine-scale population structure reveals high genetic heterogeneity of the Kuwaiti population in the Arabian Peninsula
Eaaswarkhanth, M.; Pathak, A. K.; Ongaro, L.; Montinaro, F.; Hebbar, P.; Alsmadi, O.; Metspalu, M.; Al-Mulla, F.; Thangavel, A. T.
10.1101/2020.11.23.393892 — genomics — Posted on 2020-11-23
1032 The BTB transcription factors ZBTB11 and ZFP131 maintain pluripotency by pausing POL II atpro-differentiation genes
Garipler, G.; Lu, C.; Morrissey, A.; Lopez-Zepeda, L. S.; Vidal, S. E.; Aydin, B.; Stadtfeld, M.; Ohler, U.; Mahony, S.; Sanjana, N. E.; Mazzoni, E. O.
10.1101/2020.11.23.391771 — developmental biology — Posted on 2020-11-23
1033 Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns
Chhipi Shrestha, J. K.; Schneider-Poetsch, T.; Suzuki, T.; Mito, M.; Khan, K.; Dohmae, N.; Iwasaki, S.; Yoshida, M.
10.1101/2020.11.23.393835 — molecular biology — Posted on 2020-11-23
1034 Vaccine-induced, but not natural immunity, against the Streptococcal Inhibitor of Complement protects against invasive disease
Tan, L. K. K.; Reglinski, M.; Teo, D.; Reza, N.; Lamb, L. E. M.; Nageshwaran, V.; Turner, C. E.; Wikstroem, M.; Frick, I.-M.; Bjorck, L.; Sriskandan, S.
10.1101/2020.11.22.393389 — microbiology — Posted on 2020-11-23
1035 Verticillium dahliae inoculation and in vitro propagation modify the xylem microbiome and the resistance to Verticillium wilt of a wild olive genotype
ANGUITA-MAESO, M.; TRAPERO-CASAS, J. L.; OLIVARES-GARCIA, C.; Ruano-Rosa, D.; PALOMO-RIOS, E.; JIMENEZ-DIAZ, R. M.; NAVAS-CORTES, J. A.; LANDA, B. B.
10.1101/2020.11.23.392977 — microbiology — Posted on 2020-11-23
1036 A Novel Tool for the Removal of Muscle Artefacts from EEG: Improving Data Quality in the Gamma Frequency Range
Liebisch, A. P.; Eggert, T.; Shindy, A.; Valentini, E.; Irving, S.; Stankewitz, A.; Schulz, E.
10.1101/2020.11.23.393702 — neuroscience — Posted on 2020-11-23
1038 Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
Masala, N.; Pofahl, M.; Haubrich, A. N.; Nikbakht, N.; Bohmbach, K.; Henneberger, C.; Golcuk, K.; Kelly, T.; Beck, H.
10.1101/2020.11.23.393694 — neuroscience — Posted on 2020-11-23
1039 SREBP2 delivery to striatal astrocytes normalizes transcription of cholesterol biosynthesis genes and ameliorates pathological features in Huntington's disease
Birolini, G.; Verlengia, G.; Talpo, F.; Maniezzi, C.; Zentilin, L.; Giacca, M.; Conforti, P.; Cordiglieri, C.; Caccia, C.; Leoni, V.; Taroni, F.; Biella, G.; Simonato, M.; Cattaneo, E.; Valenza, M.
10.1101/2020.11.23.393793 — neuroscience — Posted on 2020-11-23
1040 Diurnal transcript profiling of the diatom Seminavisrobusta reveals adaptations to a benthic lifestyle
Bilcke, G.; Osuna-Cruz, C. M.; Silva, M. S.; Poulsen, N.; D'hondt, S.; Bulankova, P.; Vyverman, W.; De Veylder, L.; Vandepoele, K.
10.1101/2020.11.23.393678 — systems biology — Posted on 2020-11-23
1042 Arabidopsis cell surface LRR immune receptor signaling through the EDS1-PAD4-ADR1 node
Pruitt, R. N.; Zhang, L.; Saile, S. C.; Karelina, D.; Fröhlich, K.; Wan, W.-L.; Rao, S.; Gust, A. A.; Locci, F.; Joosten, M. H. A. J.; Thomma, B. P. H. J.; Zhou, J.-M.; Dangl, J. L.; Weigel, D.; Parker, J. E.; El Kasmi, F.; Nürnberger, T.
10.1101/2020.11.23.391516 — plant biology — Posted on 2020-11-23
1043 Extracellular vesicles as predictors of individual response to exercise training in youth living with obesity
Pierdona, T. M.; Martin, A.; Obi, P. O.; Seif, S.; Bydak, B.; Eadie, A.; Brunt, K.; McGavock, J. M.; Senechal, M.; Saleem, A.
10.1101/2020.11.20.390872 — physiology — Posted on 2020-11-23
1044 Hsp22 is the key sensor and balancer in mitochondrial dynamic associated metabolic reprogramming
Zaiwa, W.; Ying, C.; Xueyi, W.; Wenjing, W.; Ning, T.; Fang, S.; Yafang, T.; Jingxin, M.; Rujia, L.; Tianchan, P.; Yanmei, H.; Quan, Z.; Lili, W.; Liangxian, L.; Xiaoli, W.; Qinghua, L.
10.1101/2020.11.22.393116 — cancer biology — Posted on 2020-11-23
1045 Targeting mitochondrial respiration and the BCL2 family in MYC-associated B-cell lymphoma
Donati, G.; Rava, M.; Filipuzzi, M.; Nicoli, P.; Cassina, L.; Verrecchia, A.; Doni, M.; Rodighiero, S.; Parodi, F.; Boletta, A.; Vellano, C. P.; Marszalek, J. R.; Draetta, G.; Amati, B.
10.1101/2020.11.22.390922 — cancer biology — Posted on 2020-11-23
1049 Conserved codon adaptation in highly expressed genes is associated with higher regularity in mRNA secondary structures
Sterken, M. G.; Wilbers, R. H. P.; Prins, P.; Snoek, B. L.; Giambasu, G. M.; Slootweg, E.; Holterman, M. H. M.; Helder, J.; Kammenga, J. E.; Schots, A.; Bakker, J.; Westerhof, L. B.
10.1101/2020.11.23.393322 — bioinformatics — Posted on 2020-11-23
1050 Milo: differential abundance testing on single-cell data using k-NN graphs
Dann, E.; Henderson, N. C.; Teichmann, S. A.; Morgan, M. D.; Marioni, J. C.
10.1101/2020.11.23.393769 — bioinformatics — Posted on 2020-11-23
1054 Synaptic vesicles dynamics in neocortical epilepsy
Vannini, E.; Restani, L.; Dilillo, M.; McDonnell, L.; Caleo, M.; Marra, V.
10.1101/2020.01.05.895029 — neuroscience — Posted on 2020-11-23
1056 Operation of a TCA cycle subnetwork in the mammalian nucleus
Kafkia, E.; Andres-Pons, A.; Ganter, K.; Seiler, M.; Jouhten, P.; Pereira, F.; Zaugg, J. B.; Lancrin, C.; Beck, M.; Patil, K. R.
10.1101/2020.11.22.393413 — systems biology — Posted on 2020-11-23
1057 Inhibition of SARS-CoV-2 main protease by allosteric drug-binding
Guenther, S.; Reinke, P. Y. A.; Fernandez-Garcia, Y.; Lieske, J.; Lane, T. J.; Ginn, H.; Koua, F.; Ehrt, C.; Ewert, W.; Oberthuer, D.; Yefanov, O.; Meier, S.; Lorenzen, K.; Krichel, B.; Kopicki, J.; Gelisio, L.; Brehm, W.; Dunkel, I.; Seychell, B.; Gieseler, H.; Norton-Baker, B.; Escudero-Perez, B.; Domaracky, M.; Saouane, S.; Tolstikova, A.; White, T.; Haenle, A.; Groessler, M.; Fleckenstein, H.; Trost, F.; Galchenkova, M.; Gevorkov, Y.; Li, C.; Awel, S.; Peck, A.; Barthelmess, M.; Schluenzen, F.; Lourdu, X. P.; Werner, N.; Andaleeb, H.; Ullah, N.; Falke, S.; Srinivasan, V.; Franca, B.; Schwi
10.1101/2020.11.12.378422 — biophysics — Posted on 2020-11-23
1060 Xist-seeded nucleation sites form local concentration gradients of silencing proteins to inactivate the X-chromosome
Markaki, Y.; Chong, J. G.; Luong, C.; Tan, S. Y. X.; Wang, Y.; Jacobson, E. C.; Maestrini, D.; Dror, I.; Mistry, B. A.; Schoeneberg, J.; Banerjee, A.; Guttman, M.; Chou, T.; Plath, K.
10.1101/2020.11.22.393546 — cell biology — Posted on 2020-11-23
1063 ACTN3 genotype influences skeletal muscle mass regulation and response to dexamethasone
Seto, J. T.; Roeszler, K. N.; Meehan, L. R.; Wood, H. D.; Tiong, C.; Bek, L.; Lee, S. F.; Shah, M.; Quinlan, K. G.; Gregorevic, P.; Houweling, P. J.; North, K. N.
10.1101/2020.11.20.392282 — genetics — Posted on 2020-11-23
1064 Suppressing or blocking Fis1 reverses diabetic endothelial dysfunction in human resistance arteries
Karkala, M.; Egner, J. M.; Wang, J.; Harwig, M. C.; Meacham, K. A.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Trykall, D. Z.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2020-11-23
1065 Rifampicin exposure reveals within-host Mycobacterium tuberculosis diversity in patients with delayed culture conversion
Genestet, C.; Hodille, E.; Barbry, A.; Berland, J.-L.; Hoffmann, J.; Westeel, E.; Bastian, F.; Guichardant, M.; Venner, S.; Lina, G.; Ginevra, C.; Ader, F.; Goutelle, S.; Dumitrescu, O.; on behalf of the Lyon TB study group,
10.1101/2020.05.22.110775 — microbiology — Posted on 2020-11-23
1066 FtsZ treadmilling is essential for Z-ring condensation and septal constriction initiation in Bacillus subtilis cell division
Whitley, K. D.; Jukes, C.; Tregidgo, N.; Karinou, E.; Almada, P.; Henriques, R. D.; Dekker, C.; Holden, S.
10.1101/2020.07.01.182006 — microbiology — Posted on 2020-11-23
1068 Large-scale transcriptomics to dissect two years of the life of a fungal phytopathogen interacting with its host plant
Gay, E. J.; Soyer, J. L.; Lapalu, N.; Linglin, J.; Fudal, I.; Da Silva, C.; Wincker, P.; Aury, J.-M.; Cruaud, C.; Levrel, A.; Lemoine, J.; Delourme, R.; Rouxel, T.; Balesdent, M.-H.
10.1101/2020.10.13.331520 — pathology — Posted on 2020-11-23
1069 PHERI - Phage Host Exploration pipeline.
Balaz, A.; Kajsik, M.; Budis, J.; Szemes, T.; Turna, J.
10.1101/2020.05.13.093773 — bioinformatics — Posted on 2020-11-23
1072 Nucleo-cytoplasmic shuttling of splicing factor SRSF1 is required for development and cilia function
Haward, F.; Maslon, M. M.; Yeyati, P. L.; Bellora, N.; Hansen, J. N.; Aitken, S.; Lawson, J.; von Kriegsheim, A.; Wachten, D.; Mill, P.; Adams, I. R.; Caceres, J. F.
10.1101/2020.09.04.263251 — molecular biology — Posted on 2020-11-23
1073 Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
Gonzalez-Pena, V.; Natarajan, S.; Xia, Y.; Klein, D.; Carter, R.; Pang, Y.; Shaner, B.; Annu, K.; Putnam, D. K.; Chen, W.; Connelly, J.; Pruett-Miller, S. M.; Chen, X.; Easton, J.; Gawad, C.
10.1101/2020.11.20.391961 — genomics — Posted on 2020-11-23
1075 The APETALA2 transcription factor LsAP2 regulates seed shape in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Wang, Y.; Yang, J.; Qi, M.; Wang, Q.
10.1101/2020.11.05.370684 — plant biology — Posted on 2020-11-23
1076 Thermal Hazards for Honey Bee Queens
McAfee, A.; Chapman, A.; Higo, H.; Underwood, R. M.; Milone, J. P.; Foster, L. J.; Guarna, M. M.; Tarpy, D. R.; Pettis, J. S.
10.1101/627729 — physiology — Posted on 2020-11-23
1078 Trophic cascade driven by behavioural fine-tuning as naive prey rapidly adjust to a novel predator
Jolly, C. J.; Smart, A. S.; Moreen, J.; Webb, J. K.; Gillespie, G. R.; Phillips, B. L.
10.1101/856997 — ecology — Posted on 2020-11-22
1079 Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala
Kang, S. J.; Liu, S.; Ye, M.; Kim, D.-I.; Kim, J.-H.; Oh, T. G.; Peng, J.; Evans, R. M.; Lee, K.-F.; Goulding, M.; Han, S.
10.1101/2020.11.17.385104 — neuroscience — Posted on 2020-11-23
1081 GEMC1-MCIDAS transcriptional program regulates multiciliogenesis in the choroid plexus and acts as a barrier to tumorigenesis
Li, Q.; Han, Z.; Singh, N.; Terre, B.; Fame, R. M.; Arif, U.; Page, T. D.; Zahran, T.; Abdeltawab, A.; Huang, Y.; Cao, P.; Wang, J.; Lu, H.; Lidov, H. G. W.; Surendran, K.; Wu, L.; Schuller, U.; Wechsler-Reya, R. J.; Lehtinen, M. K.; Roy, S.; Liu, Z.; Stracker, T. H.; Zhao, H.
10.1101/2020.11.22.393298 — cancer biology — Posted on 2020-11-22
1082 Modulation of implanted aortic scaffold- involvement of ECM and immune proteins
Banerjee, D.; Nayakawde, N. B.; Antony, D.; Deshmukh, M.; Ghosh, S.; Sihlbom, C.; Ul Haq, U.; Olausson, M.
10.1101/2020.11.21.392654 — bioengineering — Posted on 2020-11-22
1085 TASOR epigenetic repressor cooperates with a CNOT1 RNA degradation pathway to repress HIV
Matkovic, R.; Morel, M.; Larrous, P.; Martin, B.; Bejjani, F.; Emiliani, S.; Gallois-Montbrun, S.; Margottin-Goguet, F.
10.1101/2020.11.22.386656 — molecular biology — Posted on 2020-11-22
1086 Loss of consciousness reduces the stability of brain hubs and the heterogeneity of brain dynamics
Lopez-Gonzalez, A.; Panda, R.; Ponce-Alvarez, A.; Zamora, G.; Escrichs, A.; Martial, C.; Thibaut, A.; Gosseries, O.; Kringelbach, M. L.; Annen, J.; Laureys, S.; Deco, G.
10.1101/2020.11.20.391482 — neuroscience — Posted on 2020-11-22
1088 Hippocampal Transcriptome Profiling Reveals Common Disease Pathways in Chronic Hypoperfusion and Ageing
Baik, S.-H.; Selvaraji, S.; Fann, D. Y.; Jo, D.-G.; Herr, D. R.; Lai, M. K. P.; Chen, C. L.-H.; Drummond, G. R.; Lim, K.-L.; Sobey, C. G.; Arumugam, T.
10.1101/2020.11.21.392449 — neuroscience — Posted on 2020-11-22
1089 Constructing spatial perception through self-touch
Cataldo, A.; Dupin, L.; Dempsey-Jones, H.; Gomi, H.; Haggard, P.
10.1101/2020.11.21.392563 — neuroscience — Posted on 2020-11-22
1090 Age-related Changes in Memory for Object and Position-In-Context
Tran, T. T.; Tobin, K. E.; Block, S. H.; Puliyadi, V.; Gallagher, M.; Bakker, A.
10.1101/2020.11.22.393355 — neuroscience — Posted on 2020-11-22
1094 Sex Differences in MRI-Based Metrics of Glioma Invasion and Brain Mechanics
Anderies, B. J.; Yee, S. F.; Jackson, P. R.; Rickertsen, C. R.; Hawkins-Daarud, A. J.; Johnston, S. K.; Clark-Swanson, K. R.; Hoxworth, J. M.; Le, Y.; Zhou, Y.; Pepin, K. M.; Massey, S. C.; Hu, L. S.; Huston, J. R.; Swanson, K. R.
10.1101/2020.11.21.352724 — biophysics — Posted on 2020-11-22
1096 Genome Wide Association Studies on 7 Yield-relatedTraits of 183 Rice Varieties in Bangladesh
Roy, N.; Kabir, A. H.; Zahan, N.; Mouna, S. T.; Chakravarty, S.; Rahman, A. H.; Bayzid, M. S.
10.1101/2020.11.22.393074 — bioinformatics — Posted on 2020-11-22
1097 Inferring the spatial code of cell-cell interactions and communication across a whole animal body
Armingol, E.; Joshi, C. J.; Baghdassarian, H.; Shamie, I.; Ghaddar, A.; Chan, J.; Her, H.-L.; O'Rourke, E. J.; Lewis, N. E.
10.1101/2020.11.22.392217 — bioinformatics — Posted on 2020-11-22
1098 A probabilistic model for indel evolution: differentiating insertions from deletions
Loewenthal, G.; Rapoport, D.; Avram, O.; Moshe, A.; Itzkovitch, A.; Israeli, O.; Azouri, D.; Cartwright, R. A.; Mayrose, I.; Pupko, T.
10.1101/2020.11.22.393108 — bioinformatics — Posted on 2020-11-22
1100 Dietary zinc restriction induces nociceptive pain with reduced inflammation in mice
de Lima, C. K. F.; Sisnande, T.; da Silva, R. V.; da Silva, V. D.; do Amaral, J. J.; Ochs, S. M.; Roedel dos Santos, B. L.; Miranda, A. L. P.; Lima, L. M. T. d. R.
10.1101/2020.11.21.392548 — biochemistry — Posted on 2020-11-22
1101 From qualitative to quantitative insect metabarcoding: an in tandem multilocus mosquito identification methodology
Kassela, K.; Kouvela, A.; De Courcy Williams, M.; Konstantinidis, K.; Rosa-Freitas, M. G.; Nearchou, A.; Gatzidou, E.; Veletza, S.; Boulougouris, G. C.; Dovrolis, N.; Karakasiliotis, I.
10.1101/2020.11.22.393140 — genomics — Posted on 2020-11-22
1107 Inhibition of Biofilm Formation by Modified Oxylipins from the Shipworm Symbiont Teredinibacter turnerae
Lacerna, N. M.; Ramones, C. M. V.; Robes, J. M. D.; Picart, M. R. D.; Tun, J. O.; Miller, B. W.; Haygood, M. G.; Schmidt, E. W.; Salvador-Reyes, L.; Concepcion, G. P.
10.1101/2020.11.22.393314 — microbiology — Posted on 2020-11-22
1112 Impact of transposable elements on the genome of the urban malaria vector Anopheles coluzzii
Vargas-Chavez, C.; Longo Pendy, N. M.; Nsango, S.; Aguilera, L.; Ayala, D.; Gonzalez, J.
10.1101/2020.11.22.393231 — genomics — Posted on 2020-11-22
1116 Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
PINTO, G.; SAENZ DE SANTA MARIA, I.; CHASTAGNER, P.; Perthame, E.; DELMAS, C.; TOULAS, C.; Moyal-Jonathan-Cohen, E.; BROU, C.; ZURZOLO, C.
10.1101/2020.11.21.392597 — cancer biology — Posted on 2020-11-22
1118 Circadian fluctuations in glucocorticoid level impact perceptual sensitivity
Obleser, J.; Kreitewolf, J.; Vielhauer, R.; Lindner, F.; David, C.; Oster, H.; Tune, S.
10.1101/2020.10.07.330282 — neuroscience — Posted on 2020-11-22
1119 A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival
Abassah-Oppong, S.; Mannion, B.; Tissieres, V.; Rodriguez-Carballo, E.; Ljubojevic, A.; Darbellay, F.; Festa, T. A.; Sullivan, C. S.; Kelman, G.; Hunter, R. D.; Novak, C. S.; Plajzer-Frick, I.; Tran, S.; Akiyama, J. A.; Barozzi, I.; Andrey, G.; Lopez-Rios, J.; Dickel, D. E.; Visel, A.; Pennacchio, L. A.; Cobb, J.; Osterwalder, M.
10.1101/2020.11.22.393173 — developmental biology — Posted on 2020-11-22
1120 Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 in vitro
Le-Trilling, V. T. K.; Mennerich, D.; Schuler, C.; Flores-Martinez, Y.; Katschinski, B.; Dittmer, U.; Trilling, M.
10.1101/2020.11.18.388710 — microbiology — Posted on 2020-11-22
1121 Language network connectivity increases in prodromal Alzheimer's disease
Pistono, A.; Senoussi, M.; Guerrier, L.; Rafiq, M.; Gimeno, M.; Peran, P.; Jucla, M.; Pariente, J.
10.1101/2020.11.22.393199 — neuroscience — Posted on 2020-11-22
1122 Gut microbiome activity contributes to individual variation in glycemic response in adults
Tily, H.; Perlina, A.; Patridge, E.; Gline, S.; Genkin, M.; Gopu, V.; Lindau, H.; Sjue, A.; Slavov, I.; Klitgord, N.; Vuyisich, M.; Messier, H.; Banavar, G. S.
10.1101/641019 — systems biology — Posted on 2020-11-22
1129 Metabolic profile discriminates and predicts Arabidopsis susceptibility to virus under field conditions
Rubio, B.; Fernandez, O.; Cosson, P.; Berton, T.; Caballero, M.; Roux, F.; Bergelson, J.; Gibon, Y.; Schurdi-Levraud, V.
10.1101/2020.11.21.392688 — plant biology — Posted on 2020-11-22
1130 STAT3 inhibits Myocardin induced cardiac hypertrophy
Liao, X.-H.; Xiang, Y.; Li, J.-P.; Li, H.; Huang, Y.; Shen, C.; zhang, Z.; Zhang, T.-C.
10.1101/2020.11.21.392902 — cell biology — Posted on 2020-11-22
1131 Correcting for Superficial Bias in 7T Gradient Echo fMRI
Huang, P.; Correia, M. M.; Rua, C.; Rodgers, C. T.; Henson, R. N.; Carlin, J. D.
10.1101/2020.11.20.392258 — neuroscience — Posted on 2020-11-22
1134 Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
ZURZOLO, C.; PINTO, G.; SAENZ DE SANTA MARIA, I.; CHASTAGNER, P.; Perthame, E.; DELMAS, C.; TOULAS, C.; Moyal-Jonathan-Cohen, E.; BROU, C.
10.1101/2020.11.21.392597 — cancer biology — Posted on 2020-11-22
1135 Public LC-Orbitrap-MS/MS Spectral Library for Metabolite Identification
Phapale, P.; Palmer, A.; Gathungu, R. M.; Kale, D.; Brugger, B.; Alexandrov, T.
10.1101/2020.11.21.392266 — biochemistry — Posted on 2020-11-22
1136 Automatic Analysis of Bees' Waggle Dance
Reece, J.; Couvillon, M. J.; Grueter, C.; Ratnieks, F.; Reyes-Aldasoro, C. C.
10.1101/2020.11.21.354019 — animal behavior and cognition — Posted on 2020-11-22
1137 Influence of spatial arrangement, biofertilizers and bioirrigation on the performance of legume-millet intercropping system in rainfed areas of southern India
Singh, D.; Mathimaran, N.; Sekar, J.; Ramalingam, P. V.; Perisamy, Y.; Raju, K.; Raj, R.; King, I. O.; Nanjundegowda, T. M.; Narayanswamy, M. B.; Chikkegowda, B. N.; Siddegowda, S. M.; Bagyaraj, D. J.; Maeder, P.; Boller, T.; Kahmen, A.
10.1101/2020.11.20.387886 — ecology — Posted on 2020-11-22
1138 DNA methylation age analysis of rapamycin in common marmosets
Horvath, S.; Zoller, J. A.; Haghani, A.; Lu, A.; Lu, A. T.; Raj, K.; Jasinska, A. J.; Mattison, J. A.; Salmon, A. B.
10.1101/2020.11.21.392779 — developmental biology — Posted on 2020-11-22
1139 Mechanosensitive Ion Channel Piezo1 Regulates Myocyte Fusion during Skeletal Myogenesis
Ortuste Quiroga, H. P.; Yokoyama, S.; Ganassi, M.; Nakamura, K.; Yamashita, T.; Raimbach, D.; Hagiwara, A.; Asakura, A.; Suzuki, Y.; Tominaga, M.; Zammit, P. S.; Goto, K.
10.1101/2020.09.27.315242 — molecular biology — Posted on 2020-11-22
1140 N6-methyladenosine (m6A) is an endogenous A3 adenosine receptor ligand
Ogawa, A.; Nagiri, C.; Shihoya, W.; Inoue, A.; Kawakami, K.; Hiratsuka, S.; Aoki, J.; Ito, Y.; Suzuki, T.; Suzuki, T.; Inoue, T.; Nureki, O.; Tanihara, H.; Tomizawa, K.; Wei, F.-Y.
10.1101/2020.11.21.391136 — molecular biology — Posted on 2020-11-22
1141 Novel Cluster AZ Arthrobacter phages Powerpuff, Lego, and YesChef exhibit close functional relationships with Microbacterium phages
Kapinos, A.; Aghamalian, P.; Capehart, E.; Alag, A.; Angel, H.; Briseno, E.; Choe, E.; Corado-Perez, B.; Farag, E.; Foster, H.; Hakim, A.; Hernandez-Casas, D.; Huang, C.; Lam, D.; Mendez, M.; Min, A.; Nguyen, N.; Omholt, A. L.; Ortiz, E.; Saldivar, L. S.; Shannon, J. A.; Smith, R.; Sridhar, M. V.; Ta, A.; Theophilus, M. C.; Wang, S.; Ngo, R.; Torres, C.; Reddi, K.; Freise, A. C.; Moberg Parker, J.
10.1101/2020.11.21.392811 — microbiology — Posted on 2020-11-22
1144 Women with a history of previous childbirths show less evident white matter brain ageing
Voldsbekk, I.; Barth, C.; Maximov, I. I.; Kaufmann, T.; Beck, D.; Richard, G.; Moberget, T.; Westlye, L. T.; de Lange, A.-M. G.
10.1101/2020.11.20.391698 — neuroscience — Posted on 2020-11-22
1150 A comprehensive analysis of the global human gut archaeome from a thousand genome catalogue
Chibani, C. M.; Mahnert, A.; Borrel, G.; Almeida, A.; Werner, A.; Brugere, J.-F.; Gribaldo, S.; Finn, R. D.; Schmitz, R. A.; Moissl-Eichinger, C.
10.1101/2020.11.21.392621 — bioinformatics — Posted on 2020-11-22
1151 A CDK-regulated chromatin segregase promoting chromosome replication
Chacin, E.; Bansal, P.; Reusswig, K.-U.; Diaz-Santin, L.; Ortega, P.; Vizjak, P.; Gomez-Gonzalez, B.; Mueller-Planitz, F.; Aguilera, A.; Pfander, B.; Cheung, A.; Kurat, C.
10.1101/2020.11.20.390914 — biochemistry — Posted on 2020-11-22
1152 CM1-driven assembly and activation of Yeast γ-Tubulin Small Complex underlies microtubule nucleation
Brilot, A. F.; Lyon, A.; Zelter, A.; Viswanath, S.; Maxwell, A.; MacCoss, M. J.; Muller, E. G.; Sali, A.; Davis, T. N.; Agard, D. A.
10.1101/2020.11.21.392803 — biochemistry — Posted on 2020-11-22
1153 Crosstalk between repair pathways elicits Double-Strand Breaks in alkylated DNA: implications for the action of temozolomide
FUCHS, R. P.; Isogawa, A.; Paulo, J. A.; Onizuka, K.; Takahashi, T.; Amunugama, R.; Duxin, J. P.; Fujii, S.
10.1101/2020.11.21.391326 — biochemistry — Posted on 2020-11-22
1155 A conserved strategy for inducing appendage regeneration
Abrams, M. J.; Tan, F. H.; Basinger, T.; Heithe, M. L.; Li, Y.; Raffiee, M.; Leahy, P.; Dabiri, J. O.; Gold, D. A.; Goentoro, L. A.
10.1101/2020.11.21.392720 — evolutionary biology — Posted on 2020-11-22
1158 Lipidomic analysis of roseobacters of the pelagic RCA cluster and their response to phosphorus limitation
Silvano, E.; Wolterink., M.; Giebel, H.; Simon, M.; Scanlan, D.; Zhao, Y.; Chen, Y.; Yang, M.
10.1101/2020.11.21.392431 — microbiology — Posted on 2020-11-22
1159 Transmission and protection against re-infection in the ferret model with the SARS-CoV-2 USA-WA1/2020 reference isolate
Patel, D. R.; Field, C. J.; Septer, K. M.; SIm, D. G.; Jones, M. J.; Heinly, T. A.; McGraw, E. A.; Sutton, T. C.
10.1101/2020.11.20.392381 — microbiology — Posted on 2020-11-22
1160 Salicylate, Bile Acids and Extreme Acid Cause Fitness Tradeoffs for Multidrug Pumps in Escherichia coli K-12
Schaffner, S. H.; Lee, A. V.; Pham, M. T.; Kassaye, B. B.; Li, H.; Tallada, S.; Lis, C.; Lang, M.; Liu, Y.; Ahmed, N.; Galbraith, L. G.; Moore, J. P.; Bischof, K. M.; Slonczewski, J. L.
10.1101/2020.11.21.392837 — microbiology — Posted on 2020-11-22
1161 Harmonization of whole genome sequencing for outbreak surveillance of Enterobacteriaceae and Enterococci
Jamin, C.; de Koster, S.; van Koeveringe, S.; de Coninck, D.; Mensaert, K.; de Bruyne, K.; Perales Selva, N.; Lammens, C.; Goossens, H.; Hoebe, C. J.; Savelkoul, P.; van Alphen, L. B.
10.1101/2020.11.20.392399 — microbiology — Posted on 2020-11-22
1162 Anti-COVID-19 efficacy of ivermectin in the golden hamster
de Melo, G. D.; Lazarini, F.; Larrous, F.; Feige, L.; Kergoat, L.; Marchio, A.; Pineau, P.; Lecuit, M.; Lledo, P.-M.; Changeux, J.-P.; Bourhy, H.
10.1101/2020.11.21.392639 — immunology — Posted on 2020-11-22
1166 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; Sorokin, E.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-11-21
1167 Predicting MEG resting-state functional connectivity using microstructural information
Messaritaki, E.; Foley, S.; Schiavi, S.; Magazzini, L.; Routley, B.; Jones, D. K.; Singh, K. D.
10.1101/2020.09.15.298307 — neuroscience — Posted on 2020-11-21
1168 Loss of integration of brain networks after sleep deprivation relates to the worsening of cognitive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Sorrentino, G.; Mandolesi, L.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-11-21
1169 The role of dopamine in reward-based motor adaptation, savings, and interference
Palidis, D. J.; McGregor, H. R.; Vo, A.; MacDonald, P. A.; Gribble, P. L.
10.1101/2020.11.19.390302 — neuroscience — Posted on 2020-11-21
1172 Sex of donor cell and reprogramming conditions predict the extent and nature of imprinting defects in mouse iPSCs
Arez, M.; Eckersley-Maslin, M.; Klobucar, T.; von Gilsa Lopes, J.; Krueger, F.; Raposo, A.; Gendrel, A.-V.; Bernardes de Jesus, B.; Teixeira da Rocha, S.
10.1101/2020.11.20.370973 — molecular biology — Posted on 2020-11-21
1173 AIM2 Inflammasome Mediates Hallmark Neuropathological Alterations and Cognitive Impairment in a Mouse Model of Vascular Dementia
Poh, L.; Fann, D.; Wong, P.; Lim, H. M.; Foo, S. L.; Kang, S.-W.; Rajeev, V.; Selvaraji, S.; Rajagopal Iyer, V.; Parathy, N.; Khan, M. B.; Hess, D. C.; Jo, D.-G.; Drummond, G. R.; Sobey, C. G.; Lai, M. K. P.; Chen, C. L.-H.; Lim, L. H. K.; Arumugam, T. V.
10.1101/2020.06.05.135228 — neuroscience — Posted on 2020-11-21
1174 Distinct and Common Neural Coding of Semantic and Non-semantic Control Demands
Gao, Z.; Zheng, L.; Chiou, R.; Gouws, A.; Krieger-Redwood, K.; Wang, X.; Varga, D.; Lambon Ralph, M.; Smallwood, J.; Jefferies, E.
10.1101/2020.11.16.384883 — neuroscience — Posted on 2020-11-21
1175 Reduction in CD11c+ microglia promotes clinical progression in autoimmune demyelination
Mayrhofer, F.; Dariychuk, Z.; Zhen, A.; Daugherty, D. J.; Bannerman, P.; Hanson, A. M.; Pleasure, D. E.; Soulika, A.; Deng, W.; Chechneva, O.
10.1101/396036 — neuroscience — Posted on 2020-11-21
1183 Dilp8 controls a time window for tissue size adjustment in Drosophila
Boulan, L.; Blanco-Obregon, D.; El Marzkioui, K.; Brutscher, F.; Andersen, D. S.; Colombani, J.; Narasimha, S.; Leopold, P.
10.1101/2020.11.09.375063 — developmental biology — Posted on 2020-11-21
1189 Comparative biochemistry of four polyester (PET) hydrolases
Arnling Baath, J.; Borch, K.; Jensen, K.; Brask, J.; Westh, P.
10.1101/2020.11.20.392019 — biochemistry — Posted on 2020-11-21
1190 The impact of biological sex on alternative splicing
Karlebach, G.; Veiga, D. F. T.; Deslattes Mays, A.; Chatzipantsiou, C.; Prieto Barja, P.; Chatzou, M.; Kesarwani, A. K.; Danis, D.; Kararigas, G.; Zhang, X. A.; George, J.; Steinhaus, R.; Hansen, P.; Seelow, D.; McMurry, J. A.; Haendel, M. A.; Yang, J.; Oprea, T.; Anczukow, O.; Banchereau, J.; Robinson, P. N.
10.1101/490904 — genomics — Posted on 2020-11-21
1192 Three-dimensional interrelationship between osteocyte network and forming mineral during human bone remodeling
Ayoubi, M.; van Tol, A. F.; Weinkamer, R.; Roschger, P.; Brugger, P.; Berzlanovich, A.; Bertinetti, L.; Roschger, A.; Fratzl, P.
10.1101/2020.11.20.391862 — biophysics — Posted on 2020-11-21
1193 KIR2DL4 genetic diversity in a Brazilian population sample: implications for transcription regulation and protein diversity in samples with different ancestry backgrounds
Weiss, E.; Andrade, H. S.; Lara, J. R.; Souza, A. S.; Paz, M. A.; Lima, T. A.; Porto, I. O.; Silva, N. S.; Castro, C. F.; Grotto, R.; Donadi, E. A.; Mendes-Junior, C. T.; Castelli, E. C.
10.1101/2020.11.20.391649 — genetics — Posted on 2020-11-21
1194 Convergent consequences of parthenogenesis on stick insect genomes
Jaron, K. S.; Parker, D. J.; Anselmetti, Y.; Tran Van, P.; Bast, J.; Dumas, Z.; Figuet, E.; Francois, C. M.; Hayward, K.; Rossier, V.; Simion, P.; Robinson-Rechavi, M.; Galtier, N.; Schwander, T.
10.1101/2020.11.20.391540 — evolutionary biology — Posted on 2020-11-21
1195 Highly multiplexed spatially resolved gene expression profiling of mouse organogenesis
Lohoff, T.; Ghazanfar, S.; Missarova, A.; Koulena, N.; Pierson, N.; Griffiths, J. A.; Bardot, E. S.; Eng, C.-H. L.; Tyser, R. C. V.; Argelaguet, R.; Guibentif, C.; Srinivas, S.; Briscoe, J.; Simons, B. D.; Hadjantonakis, A.-K.; Gottgens, B.; Reik, W.; Nichols, J.; Cai, L.; Marioni, J. C.
10.1101/2020.11.20.391896 — developmental biology — Posted on 2020-11-21
1196 Microbial Metagenomic Approach Uncovers the First Rabbit Haemorrhagic Disease Virus genome in Sub-Saharan Africa
Happi, A. N.; Ogunsanya, O. A.; Oguzie, J.; Oluniyi, P. E.; Olono, A. S.; Heeney, J. L.; Happi, C.
10.1101/2020.11.19.390559 — molecular biology — Posted on 2020-11-21
1197 Integrating taxonomic, functional, and strain-level profiling of diverse microbial communities with bioBakery 3
Beghini, F.; McIver, L. J.; Blanco-Miguez, A.; Dubois, L.; Asnicar, F.; Maharjan, S.; Mailyan, A.; Thomas, A. M.; Manghi, P.; Valles-Colomer, M.; Weingart, G.; Zhang, Y.; Zolfo, M.; Huttenhower, C.; Franzosa, E. A.; Segata, N.
10.1101/2020.11.19.388223 — microbiology — Posted on 2020-11-21
1198 A single bacterial sulfatase is required for metabolism of colonic mucin O-glycans and intestinal colonization by a symbiotic human gut bacterium
Luis, A. S.; Jin, C.; Vasconcelos Pereira, G.; Glowacki, R. W. P.; Gugel, S.; Singh, S.; Byrne, D. P.; Pudlo, N. A.; London, J. A.; Basle, A.; Reihill, M.; Oscarson, S.; Eyers, P.; Czjzek, M.; Michel, G.; Barbeyron, T.; Yates, E. A.; Hansson, G. C.; Karlsson, N. G.; Cartmell, A.; Martens, E. C.
10.1101/2020.11.20.392076 — microbiology — Posted on 2020-11-21
1201 IBEX: A versatile multi-plex optical imaging approach for deep phenotyping and spatial analysis of cells in complex tissues
Radtke, A. J.; Kandov, E.; Lowekamp, B.; Speranza, E.; Chu, C. J.; Gola, A.; Thakur, N.; Shih, R.; Yao, L.; Yaniv, Z. R.; Beuschel, R. T.; Kabat, J.; Croteau, J.; Davis, J.; Hernandez, J. M.; Germain, R. N.
10.1101/2020.11.20.390690 — immunology — Posted on 2020-11-21
1202 High-Grade Serous Ovarian Tumor Cells Modulate NK Cell Function to Create an Immune-Tolerant Microenvironment
Gonzalez, V. D.; Huang, Y.-W.; Chen, S.-Y.; Delgado-Gonzalez, A.; Donoso, K.; Gentles, A.; Sachs, K.; Porpiglia, E.; Fantl, W.
10.1101/2020.11.20.391706 — immunology — Posted on 2020-11-21
1203 Individual and combined effects of Cannabidiol (CBD) and Δ9-tetrahydrocannabinol (THC) on striato-cortical connectivity in the human brain
Wall, M. B.; Freeman, T. P.; Hindocha, C.; Demetriou, L.; Ertl, N.; Freeman, A. M.; Jones, A. P. M.; Lawn, W.; Pope, R.; Mokrysz, C.; Solomons, D.; Statton, B.; Walker, H. R.; Yamamori, Y.; Yang, Z.; Yim, J. L. L.; Nutt, D. J.; Howes, O. D.; Curran, H. V.; Bloomfield, M.
10.1101/2020.11.20.391805 — neuroscience — Posted on 2020-11-21
1204 Age-Associated Insolubility of Parkin in Human Midbrain is Linked to Redox Balance and Sequestration of Reactive Dopamine Metabolites
Tokarew, J. M.; El Kodsi, D. N.; Lengacher, N. A.; Fehr, T. K.; Nguyen, A. P.; Shutinoski, B.; O'Nuallain, B.; Jin, M.; Khan, J.; Ng, A. C. H.; Li, J.; Jiang, Q.; Zhang, M.; Wang, L.; Sengupta, R.; Barber, K.; Tran, A.; Zandee, S.; Dong, X.; Scherzer, C. R.; Prat, A.; Tsai, E.; Takanashi, M.; Hattori, N.; Chan, J. A.; Zecca, L.; West, A.; Holmgren, A.; Puente, L.; Shaw, G. S.; Toth, G.; Woulfe, J.; Taylor, P.; Tomlinson, J. J.; Schlossmacher, M. G.
10.1101/2020.11.20.392175 — neuroscience — Posted on 2020-11-21
1205 Exploring the limits of ComBat method for multi-site diffusion MRI harmonization
Cetin-Karayumak, S.; Stegmayer, K.; Walther, S.; Szeszko, P. R.; Crow, T.; James, A.; Keshavan, M.; Kubicki, M.; Rathi, Y.
10.1101/2020.11.20.390120 — neuroscience — Posted on 2020-11-21
1206 The effects of different frequencies of rhythmic acoustic stimulation on gait kinematics and trunk sway in healthy elderly population
Minino, R.; Troisi Lopez, E.; Sorrentino, P.; Rucco, R.; Lardone, A.; Pesoli, M.; Tafuri, D.; Mandolesi, L.; Sorrentino, G.; Liparoti, M.
10.1101/2020.11.20.390955 — neuroscience — Posted on 2020-11-21
1207 DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring ageing and degeneration dynamics
Tam, V.; Chen, P.; Yee, A.; Solis, N.; Klein, T.; Kudelko, M.; Sharma, R.; Chan, W. C.; Overall, C. M.; Haglund, L.; Sham, P. C.; Cheah, K. S.; Chan, D.
10.1101/2020.07.11.192948 — systems biology — Posted on 2020-11-21
1209 ATP drives efficient terpene biosynthesis in marine thraustochytrids
Zhang, A.; Mernitz, K. A.; Wu, C.; Xiong, W.; He, Y.; Wang, G.; Wang, X.
10.1101/2020.11.20.391870 — systems biology — Posted on 2020-11-21
1212 Clipper: p-value-free FDR control on high-throughput data from two conditions
Ge, X.; Chen, Y. E.; Song, D.; McDermott, M.; Woyshner, K.; Manousopoulou, A.; Wang, L. D.; Li, W.; Li, J. J.
10.1101/2020.11.19.390773 — bioinformatics — Posted on 2020-11-21
1213 Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
Dalvie, N. C.; Brady, J. R.; Crowell, L. E.; Tracey, M. K.; Biedermann, A. M.; Kaur, K.; Hickey, J. M.; Kristensen, D. L.; Bonnyman, A.; Rodriguez-Aponte, S. A.; Whittaker, C. A.; Bok, M.; Vega, C.; Mukhopadhyay, T.; Joshi, S. B.; Volkin, D. B.; Parreno, V.; Love, K. R.; Love, J. C.
10.1101/2020.11.20.391532 — bioengineering — Posted on 2020-11-20
1214 Dynamics of gene expression and chromatin marking during cell state transition
Borsari, B.; Abad, A.; Klein, C. C.; Nurtdinov, R.; Esteban, A.; Palumbo, E.; Ruiz-Romero, M.; Sanz, M.; Correa, B. R.; Johnson, R.; Perez-Lluch, S.; Guigo, R.
10.1101/2020.11.20.391524 — genomics — Posted on 2020-11-20
1215 Accurate Genomic Variant Detection in Single Cells with Primary Template-Directed Amplification
Gawad, C.; Klein, D.; Gonzalez-Pena, V.; Natarajan, S.; Carter, R.; Pruett-Miller, S. M.; Xia, Y.; Easton, J.; Chen, X.; Pang, Y.; Annu, K.; Shaner, B.; Putnam, D. K.; Chen, W.; Connelly, J.
10.1101/2020.11.20.391961 — genomics — Posted on 2020-11-20
1216 Transgenerational inheritance of BPA-induced obesity correlates with transmission of new CTCF sites in the Fto gene
Jung, Y. H.; Bixler, B. J.; Ruiz, D.; Wang, H.-L. V.; Linsenbaum, H.; Xiang, J.-F.; Shafik, A. M.; Jin, P.; Corces, V. G.
10.1101/2020.11.20.391672 — genomics — Posted on 2020-11-20
1217 Scalable pooled CRISPR screens with single-cell chromatin accessibility profiling
Liscovitch-Brauer, N.; Montalbano, A.; Deng, J.; Mendez-Mancilla, A.; Wessels, H.-H.; Moss, N. G.; Kung, C.-Y.; Sookdeo, A.; Guo, X.; Geller, E.; Jaini, S.; Smibert, P.; Sanjana, N. E.
10.1101/2020.11.20.390971 — genomics — Posted on 2020-11-20
1219 Impacts of water quality on Acropora coral settlement: The relative importance of substrate quality and light
Ricardo, G. F.; Harper, C. E.; Negri, A. P.; Luter, H. M.; Abdul Wahab, M. A.; Jones, R. J.
10.1101/2020.11.19.390724 — ecology — Posted on 2020-11-20
1223 Control of mitochondrial superoxide production includes programmed mtDNA deletion and restoration
Stenberg, S.; Li, J.; Gjuvsland, A. B.; Persson, K.; Demitz-Helin, E.; Yue, J.-X.; Gilchrist, C.; Ärengard, T.; Ghiaci, P.; Larsson-Berglund, L.; Zackrisson, M.; Höög, J. L.; Molin, M.; Liti, G.; Omholt, S. W.; Warringer, J.
10.1101/2020.11.20.391110 — cell biology — Posted on 2020-11-20
1224 Breast cancer dormancy is associated with a 4NG1 state and not senescence
Prunier, C.; Alay, A.; van Dijk, M.; Ammerlaan, K. L.; van Gelderen, S.; Marvin, D. L.; Teunisse, A.; Slieker, R. C.; Szuhai, K.; Jochemsen, A. G.; Sole, X.; ten Dijke, P.; Ritsma, L.
10.1101/2020.11.20.367698 — cell biology — Posted on 2020-11-21
1225 Spatio-temporal Control of ERK Pulse Frequency Coordinates Fate Decisions during Mammary Acinar Morphogenesis
Ender, P.; Gagliardi, P. A.; Dobrzynski, M.; Dessauges, C.; Höhener, T.; Jacques, M.-A.; Cohen, A. R.; Pertz, O.
10.1101/2020.11.20.387167 — cell biology — Posted on 2020-11-21
1227 Functional self-nonamerization of the Type III translocase chaperone/exported protein receptor
Yuan, B.; Portaliou, A. G.; Li, Y.; Wald, J.; Smit, J. H.; Dhupar, H. S.; Srinivasu, B. Y.; Loos, M. S.; Kalodimos, C. G.; Duong, F.; Cordes, T.; Marlovits, T. C.; Economou, A.; Karamanou, S.
10.1101/2020.11.20.391094 — molecular biology — Posted on 2020-11-20
1228 Antibiotic resistance profiles and population structure of disease-associated Staphylococcus aureus infecting patients in Fort Portal Regional Referral Hospital, Western Uganda
Ackers-Johnson, G.; Kibombo, D.; Kusiima, B.; Nsubuga, M.; Kigozi, E.; Kajumbula, H. M.; Kateete, D. P.; Walwema, R.; Ackers, H. L.; Goodhead, I. B.; Birtles, R. J.; James, C. E.
10.1101/2020.11.20.371203 — microbiology — Posted on 2020-11-21
1229 Temporal dynamics of animacy categorization in the brain of patients with mild cognitive impairment
Karimi, H.; Marefat, H.; Khanbagi, M.; Kalafatis, C.; Modarres, M. H.; Vahabi, Z.; Khaligh-Razavi, S.-M.
10.1101/2020.11.20.390435 — neuroscience — Posted on 2020-11-20
1230 Genome-wide screen of genomic imprinting in endosperm and population-level analysis reveal allelic variation for imprinting in flax
Jiang, H.; Guo, D.; Ye, J.; Gao, Y.; Liu, H.; Wang, Y.; Xue, M.; Yan, Q.; Chen, J.; Duan, L.; Li, G.; Li, X.; Xie, L.
10.1101/2020.11.20.390799 — plant biology — Posted on 2020-11-20
1233 STATegra: Multi-omics data integration - A conceptual scheme with a bioinformatics pipeline
Planell, N.; Lagani, V.; Sebastian-Leon, P.; van der Kloet, F.; Ewing, E.; Karathanasis, N.; Urdangarin, A.; Arozarena, I.; Jagodic, M.; Tsamardinos, I.; Tarazona, S.; Conesa, A.; tegner, j.; Gomez-Cabrero, D.
10.1101/2020.11.20.391045 — bioinformatics — Posted on 2020-11-20
1235 Interaction of Amphiphilic Lipoarabinomannan with Host Carrier Lipoproteins in Tuberculosis Patients: Implications for Blood-based Diagnostics.
Mukundan, H.; Jakhar, S.; Sakamuri, R.; Vu, D.; Dighe, P.; Stromberg, L. R.; Lilley, L.; Hengartner, N.; Swanson, B. I.; Moreau, E.; Dorman, S. E.
10.1101/2020.11.20.391037 — microbiology — Posted on 2020-11-20
1237 Could TDX-1 explain the changes observed in endocrine pancreas due to chronic cola drink consumption in rats? A global point of view
Cao, G.; Gonzalez, J.; Ortiz Fragola, J. P.; Muller, A.; Tumarkin, M.; Moriondo, M.; Azzato, F.; Blanco, M. V.; Milei, J.
10.1101/2020.11.20.391060 — systems biology — Posted on 2020-11-20
1241 Motor sequence learning deficits in idiopathic Parkinsons disease are associated with increased substantia nigra activity
Tzvi, E.; Bey, R.; Nitschke, M.; Brueggemann, N.; Classen, J.; Muente, T. F.; Kraemer, U. M.; Rumpf, J.-J.
10.1101/2020.11.19.386193 — neuroscience — Posted on 2020-11-20
1242 Single-cell landscape of nuclear configuration and gene expression during stem cell differentiation and X inactivation
Bonora, G.; Ramani, V.; Singh, R.; Fang, H.; Jackson, D.; Srivatsan, S.; Qiu, R.; Lee, C.; Trapnell, C.; Shendure, J.; Duan, Z.; Deng, X.; Noble, W. S.; Disteche, C. M.
10.1101/2020.11.20.390765 — genomics — Posted on 2020-11-20
1243 Functional partitioning of a liquid-like organelle during assembly of axonemal dyneins
Lee, C.; Cox, R.; Papoulas, O.; Horani, A.; Drew, K.; Devitt, C.; Brody, S. L.; Marcotte, E.; Wallingford, J. B.
10.1101/2020.04.21.052837 — cell biology — Posted on 2020-11-20
1245 mTORC1 activity is supported by spatial association with focal adhesions
Rabanal-Ruiz, Y.; Byron, A.; Wirth, A.; Madsen, R. R.; Sedlackova, L.; Hewitt, G.; Nelson, G.; Stingele, J.; Faessler, R.; Vanhaesebroeck, B.; Maddocks, O.; Ponimaskin, E.; Carroll, B.; Korolchuk, V. I.
10.1101/2020.11.20.391888 — cell biology — Posted on 2020-11-20
1247 BETA- AND GAMMA-SYNUCLEINS MODULATE SYNAPTIC VESICLE-BINDING OF ALPHA-SYNUCLEIN
Carnazza, K. E.; Komer, L.; Pineda, A.; Na, Y.; Ramlall, T.; Buchman, V. L.; Eliezer, D.; Sharma, M.; Burre, J.
10.1101/2020.11.19.390419 — neuroscience — Posted on 2020-11-20
1250 Coiled-coil and RPW8-type immune receptors function at the plasma membrane in a phospholipid dependent manner
Saile, S. C.; Ackermann, F. M.; Sunil, S.; Bayless, A.; Stoebbe, E.; Bonardi, V.; Wan, L.; Doumane, M.; Jaillais, Y.; Caillaud, M.-C.; Dangl, J. L.; Nishimura, M. T.; El Kasmi, F.
10.1101/2020.11.18.388520 — plant biology — Posted on 2020-11-20
1251 Manipulating phloem transport affects wood formation but not nonstructural carbon concentrations in an evergreen conifer
Rademacher, T.; Fonti, P.; LeMoine, J. M.; Fonti, M. V.; Basler, D.; Chen, Y.; Friend, A. D.; Seyednasrollah, B.; Eckes-Shephard, A. H.; Richardson, A. D.
10.1101/2020.09.25.313569 — plant biology — Posted on 2020-11-20
1252 Deletion of Letmd1 leads to the disruption of mitochondrial function in brown adipose tissue
Song, R.; Du, Y.; Li, P.; Liu, H.; Zheng, H.; Lu, X.; Wang, S.; Zhou, L.; Rahman, N. A.; Wolczynski, S.; Kretowski, A.; Ren, F.; Li, X.; Li, X.
10.1101/2020.11.18.388199 — physiology — Posted on 2020-11-20
1256 Rooting the animal tree of life
Li, Y.; Shen, X.-X.; Evans, B.; Dunn, C. W.; Rokas, A.
10.1101/2020.10.27.357798 — evolutionary biology — Posted on 2020-11-20
1258 Global regulatory transitions at core promoters demarcate the mammalian germline cycle
Cvetesic, N.; Borkowska, M.; Hatanaka, Y.; Yu, C.; Vincent, S. D.; Mueller, F.; Tora, L.; Leitch, H. G.; Hajkova, P.; Lenhard, B.
10.1101/2020.10.30.361865 — developmental biology — Posted on 2020-11-20
1259 Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang, L.; Astone, M.; Alam, S. K.; Zhu, Z.; Pei, W.; Frank, D. A.; Burgess, S. M.; Hoeppner, L. H.
10.1101/2020.10.27.358374 — molecular biology — Posted on 2020-11-20
1261 MR1-restricted MAIT cells from the human lung mucosal surface have distinct phenotypic, functional, and transcriptomic features that are preserved in HIV infection
Khuzwayo, S.; Mthembu, M.; Meermeier, E. W.; Prakadan, S. M.; Kazer, S. W.; Bassett, T.; Nyamande, K.; Fakey Khan, D.; Maharaj, P.; Mitha, M.; Suleman, M.; Mhlane, Z.; Ramjit, D.; Khan, F.; Shalek, A. K.; Lewinsohn, D. M.; Ndung'u, T.; Wong, E. B.
10.1101/2020.11.19.389858 — immunology — Posted on 2020-11-20
1265 U-Net Model for Brain Extraction on Non-human Primates
Wang, X.; Li, X.-H.; Cho, J. W.; Russ, B.; Rajamani, N.; Omelchenko, A.; Ai, L.; Korchmaros, A.; Garcia-Saldivar, P.; Wang, Z.; Kalin, N. H.; Schroeder, C. E.; Craddock, R. C.; Fox, A. S.; Evans, A. C.; Messinger, A.; Milham, M. P.; Xu, T.
10.1101/2020.11.17.385898 — neuroscience — Posted on 2020-11-20
1266 NeuroGPU, software for NEURON modeling in GPU-based hardware
Ben-Shalom, R.; Athreya, N. S.; Cross, C.; Sanghevi, H.; Kim, K. G.; Ladd, A.; Korngreen, A.; Bouchard, K. E.; Bender, K. J.
10.1101/727560 — neuroscience — Posted on 2020-11-20
1267 Median/modal death ages of pooled European male cohorts were near-constant for ~25/30 years.
Clark, J. S. C.; Rydzewska, K.; Podsiadlo, K.; van de Wetering, T.; Ciechanowicz, A.
10.1101/2020.05.23.111971 — physiology — Posted on 2020-11-20
1268 Agreement Test Between The Six Minutes Walking Test And Four Meter Gait Speed
Nusdwinuringtyas, N.; Fransiska, T.; Sunaryo, P.; Triangto, K.; Dahlan, S.
10.1101/2020.11.20.391193 — physiology — Posted on 2020-11-20
1272 2019 Association of Biomolecular Resource Facilities Multi-Laboratory Data-Independent Acquisition Study
Neely, B. A.; Stemmer, P.; Searle, B. C.; Herring, L. E.; Martin, L.; Midha, M. K.; Phinney, B. S.; Shan, B.; Palmblad, M.; Wang, Y.; Jagtap, P. D.; Kirkpatrick, J. M.
10.1101/2020.11.20.391300 — bioinformatics — Posted on 2020-11-20
1274 CellRank for directed single-cell fate mapping
Lange, M.; Bergen, V.; Klein, M.; Setty, M.; Reuter, B.; Bakhti, M.; Lickert, H.; Ansari, M.; Schniering, J.; Schiller, H. B.; Pe'er, D.; Theis, F. J.
10.1101/2020.10.19.345983 — bioinformatics — Posted on 2020-11-20
1276 Systematic quantification of health parameters from UK Biobank abdominal MRI using deep learning
Liu, Y.; Basty, N.; Whitcher, B.; Bell, J.; Sorokin, E.; van Bruggen, N.; Thomas, E. L.; Cule, M.
10.1101/2020.07.14.187070 — genetics — Posted on 2020-11-20
1278 Are fleas highly modified Mecoptera? Phylogenomic resolution of Antliophora (Insecta: Holometabola)
Meusemann, K.; Trautwein, M.; Friedrich, F.; Beutel, R.; Wiegmann, B. M.; Donath, A.; Podsiadlowski, L.; Petersen, M.; Niehuis, O.; Mayer, C.; Bayless, K.; Shin, S.; Liu, S.; Hlinka, O.; Minh, B. Q.; Kozlov, A. M.; Morel, B.; Peters, R.; Bartel, D.; Grove, S.; Zhou, X.; Misof, B.; Yeates, D.
10.1101/2020.11.19.390666 — evolutionary biology — Posted on 2020-11-20
1279 Massive occurrence of benthic plastic debris at the abyssal seafloor beneath the Kuroshio Extension, the North West Pacific
Nakajima, R.; Tsuchiya, M.; Yabuki, A.; Masuda, S.; Kitahashi, T.; Nagano, Y.; Ikuta, T.; Isobe, N.; Nakata, H.; Ritchie, H.; Oguri, K.; Osafune, S.; Kawamura, K.; Suzukawa, M.; Yamauchi, T.; Iijima, K.; Yoshida, T.; Chiba, S.; Fujikura, K.
10.1101/2020.11.18.382754 — ecology — Posted on 2020-11-20
1280 Detecting flying insects using mega-nets and meta-barcoding
Svenningsen, C. S.; Froslev, T. G.; Bladt, J.; Pedersen, L. B.; Larsen, J. C.; Ejrnaes, R. S.; Flojgaard, C.; Hansen, A. J.; Heilmann-Clausen, J.; Dunn, R. R.; Tottrup, A. P.
10.1101/2020.11.19.389742 — ecology — Posted on 2020-11-20
1281 CD28 costimulatory domain protects against tonic signaling-induced functional impairment in CAR-Tregs
Lamarthee, B.; Marchal, A.; Charbonnier, S.; Blein, T.; Martin, E.; Vogt, K.; Titeux, M.; Delville, M.; Vincon, H.; Six, E.; Pallet, N.; Anglicheau, D.; Legendre, C.; Taupin, J.-L.; Sawitzki, B.; Latour, S.; Cavazzana, M.; Andre, I.; Zuber, J.
10.1101/2020.11.19.390450 — immunology — Posted on 2020-11-20
1286 Identification of alkylsalicylic acids in Lentisk oil (Pistacia lentiscus L.) and cytotoxicity on Human Normal Dermal Fibroblasts
BENALIA, N.; BOUMECHHOUR, A.; ORTIZ, S.; ECHAGUE, C. A.; ROSE, T.; FIEBICH, B. L.; CHEMAT, S.; MICHEL, S.; DEGUIN, B.; DAHAMNA, S.; BOUTEFNOUCHET, S.
10.1101/2020.11.17.373142 — pharmacology and toxicology — Posted on 2020-11-20
1287 Human hepatocyte PNPLA3 148M exacerbates rapid non-alcoholic steatohepatitis development in chimeric mice
Kabbani, M.; Michailidis, E.; Steensels, S.; Fulmer, C. G.; Luna, J. M.; Le Pen, J.; Tardelli, M.; Razooky, B.; Ricardo-Lax, I.; Zou, C.; Zeck, B.; Stenzel, A. F.; Quirk, C.; Foquet, L.; Ashbrook, A. W.; Schneider, W. M.; Belkaya, S.; Lalazar, G.; Liang, Y.; Pittman, M.; Devisscher, L.; Suemizu, H.; Theise, N. D.; Chiriboga, L.; Cohen, D. E.; Copenhaver, R.; Grompe, M.; Meuleman, P.; Ersoy, B. A.; Rice, C. M.; de Jong, Y. P.
10.1101/2020.11.19.387613 — pathology — Posted on 2020-11-20
1293 Arena3Dweb: Interactive 3D visualization of multilayered networks.
Karatzas, E.; Baltoumas, F. A.; Panayiotou, N. A.; Schneider, R.; Pavlopoulos, G. A.
10.1101/2020.11.20.391318 — bioinformatics — Posted on 2020-11-20
1295 Highly fluorescent biodegradable PLGA nano-carriers allows real-time tracking of individual particles in vivo
Khalin, I.; Severi, C.; Heimburger, D.; Wehn, A.; Hellal, F.; Reisch, A.; Klymchenko, A.; Plesnila, N.
10.1101/2020.11.19.385062 — bioengineering — Posted on 2020-11-20
1297 Whole Genome Sequence Analysis of Shigella from Malawi Identifies Fluoroquinolone Resistance
Stenhouse, G. E.; Jere, K. C.; Peno, C.; Bengtsson, R. J.; Chinyama, E.; Mandolo, J.; Cain, A. K.; Iturriza_Gomara, M.; Bar-Zeev, N.; Cunliffe, N. A.; Cornick, J.; Baker, K. S.
10.1101/2020.11.20.391235 — genomics — Posted on 2020-11-20
1299 Identification of high confidence human poly(A) RNA isoform scaffolds using nanopore sequencing
Mulroney, L.; Wulf, M. G.; Schildkraut, I.; Tzertzinis, G.; Buswell, J.; Jain, M.; Olsen, H.; Diekhans, M.; Correa, I. R.; Akeson, M.; Ettwiller, L.
10.1101/2020.11.18.389049 — genomics — Posted on 2020-11-20
1304 LncRNA H19X is required for placenta development and angiogenesis through regulating a noncoding RNA regulatory network
Li, T.; Cao, Y.; Zou, Y.; Ye, Y.; Wang, K.; Huang, G.; Li, X.; Zheng, R.; Tang, L.; Lv, J.; Yang, M.; He, J.; Zhang, X.; Bai, S.; Li, Q.; Qin, L.; Zhao, X. M.; Xu, W.
10.1101/2020.11.19.389940 — developmental biology — Posted on 2020-11-20
1305 Sex of donor cell and reprogramming conditions predict the extent and nature of imprinting defects in mouse iPSCs
Arez, M.; Eckersley-Maslin, M.; Klobucar, T.; von Gilsa Lopes, J.; Krueger, F. A.; Raposo, A.; Gendrel, A.-V.; Bernardes de Jesus, B.; Teixeira da Rocha, S.
10.1101/2020.11.20.370973 — molecular biology — Posted on 2020-11-20
1307 Ribonucleotide reductase, a novel target for gonorrhea
Narasimhan, J.; Letinski, S.; Jung, S.; Gerasyuto, A.; Wang, J.; Arnold, M.; Chen, G.; Hedrick, J.; Dumble, M.; Ravichandran, K.; Levitz, T.; Cui, C.; Drennan, C. L.; Stubbe, J.; Karp, G.; Branstrom, A.
10.1101/2020.11.19.389957 — microbiology — Posted on 2020-11-20
1309 Quantifying biofilm propagation on chemically modified surfaces
Halsted, M. C.; Bible, A. N.; Morrell-Falvey, J. L.; Retterer, S. T.
10.1101/2020.11.20.391797 — microbiology — Posted on 2020-11-20
1313 Complement Component 3 expressed by the endometrial ectopic tissue is involved in the endometriotic lesion formation through mast cell activation
Agostinis, C.; Zorzet, S.; Balduit, A.; Zito, G.; Mangogna, A.; Macor, P.; Romano, F.; Toffoli, M.; Belmonte, B.; Martorana, A.; Borelli, V.; Ricci, G.; Kishore, U.; Bulla, R.
10.1101/2020.11.19.389536 — immunology — Posted on 2020-11-20
1314 Pre-conditioning Modifies the Tumor Microenvironment to Enhance Solid Tumor CAR T Cell Efficacy and Endogenous Immunity
Murad, J. P.; Tilakawardane, D.; Park, A. K.; Kennewick, K. T.; Lopez, L. S.; Lee, H. J.; Gittins, B. J.; Chang, W.-C.; Tran, C. P.; Martinez, C.; Wu, A. M.; Reiter, R. E.; Dorff, T. B.; Forman, S. J.; Priceman, S. J.
10.1101/2020.11.18.388892 — immunology — Posted on 2020-11-20
1320 The role of dopamine in reward-based motor adaptation, savings, and interference
Palidis, D. J.; McGregor, H. R.; Vo, A.; MacDonald, P. A.; Gribble, P. L.
10.1101/2020.11.19.390302 — neuroscience — Posted on 2020-11-20
1321 Elucidating the neuroanatomical correlates of social connectedness, sleep quality and psychological distress in early adolescence
Jamieson, D.; McLoughlin, L. T.; Beaudequin, D. A.; Shan, Z.; Boyes, A.; Schwenn, P.; Lagopoulos, J.; Hermens, D. F.
10.1101/2020.11.19.390336 — neuroscience — Posted on 2020-11-20
1325 Human iPSC-derived astrocytes transplanted into the mouse brain display three morphological responses to amyloid-β plaques
Preman, P.; TCW, J.; Calafate, S.; Snellinx, A.; Alfonso-Triguero, M.; Corthout, N.; Munck, S.; Thal, D. R.; Goate, A. M.; De Strooper, B.; Arranz, A. M.
10.1101/2020.11.19.389023 — neuroscience — Posted on 2020-11-20
1328 Mapping the contents of consciousness during musical imagery
Regev, M.; Halpern, A. R.; Owen, A. M.; Patel, A. D.; Zatorre, R. J.
10.1101/2020.11.20.391375 — neuroscience — Posted on 2020-11-20
1330 Spatio-temporal mRNA dynamics in the early zebrafish embryo
Holler, K.; Neuschulz, A.; Drewe-Boß, P.; Mintcheva, J.; Spanjaard, B.; Arsiè, R.; Ohler, U.; Landthaler, M.; Junker, J. P.
10.1101/2020.11.19.389809 — systems biology — Posted on 2020-11-20
1333 Deletion of Letmd1 leads to the disruption of mitochondrial function in brown adipose tissue
Song, R.; Du, Y.; Li, P.; Liu, H.; Zheng, H.; Lu, X.; Wang, S.; Zhou, L.; Rahman, N. A.; Wolczynski, S.; Kretowski, A.; Ren, F.; Li, X.; Li, X.
10.1101/2020.11.18.388199 — physiology — Posted on 2020-11-20
1334 A Unique Renal Architecture in Tribolium castaneum Informs the Evolutionary Origins of Systemic Osmoregulation in Beetles
Koyama, T.; Naseem, M. T.; Kolosov, D.; Vo, C. T.; Mahon, D.; Jakobsen, A. S. S.; Jensen, R. L.; Denholm, B.; O'Donnell, M.; Halberg, K. A.
10.1101/2020.11.19.389874 — physiology — Posted on 2020-11-20
1338 Small-molecule P2RX7 activator sensitizes tumor to immunotherapy and vaccinates mouse against tumor re-challenge
Douguet, L.; Janho dit hreich, S.; Benzaquen, J.; seguin, l.; Juhel, T.; Dezitter, X.; Duranton, C.; Ryffel, B.; Kanellopoulos, J.; Delarasse, C.; Renault, N.; Furman, C.; Homerin, G.; Feral, C.; Cherfils-Vicini, J.; Millet, R.; Adriouch, S.; Ghinet, A.; Hofman, P.; Vouret-Craviari, V.
10.1101/2020.11.19.388900 — cancer biology — Posted on 2020-11-20
1339 Cancer cells are sensitive to wild-type IDH1 inhibition under nutrient limitation
Vaziri-Gohar, A.; Hue, J. J.; Graor, H. J.; Prendergast, E.; Chen, V.; Cassel, J.; Mohammed, F. S.; Abbas, A.; Dukleska, K.; Khokhar, I.; Hajhassani, O.; Zarei, M.; Wang, R.; Rothermel, L. D.; Bederman, I.; Browers, J.; Getts, R.; Brunengraber, H.; Salvino, J. M.; Brody, J. R.; Winter, J. M.
10.1101/2020.11.19.390633 — cancer biology — Posted on 2020-11-20
1340 Clinical positioning of the IAP antagonist tolinapant (ASTX660) in colorectal cancer
Longley, D. B.; Crawford, N. T.; Stott, K. J.; Sessler, T.; McCann, C.; McDaid, W.; Latimer, C.; Fox, J.; Munck, J. M.; Smyth, T.; Shah, A.; Martins, V.; Lawler, M.; Dunne, P. D.; Kerr, E. M.; McDade, S. S.; Coyle, V. M.
10.1101/2020.11.20.391680 — cancer biology — Posted on 2020-11-20
1341 AMPGAN v2: Machine Learning Guided Discovery of Anti-Microbial Peptides
Van Oort, C. M.; Ferrell, J. B.; Remington, J. M.; Wshah, S.; Li, J.
10.1101/2020.11.18.388843 — biophysics — Posted on 2020-11-20
1343 BOSO: a novel feature selection algorithm for linear regression with high-dimensional data
Valcarcel, L. V.; San Jose-Eneriz, E.; Cendoya, X.; Rubio, A.; Agirre, X.; Prosper, F.; Planes, F. J.
10.1101/2020.11.18.388579 — bioinformatics — Posted on 2020-11-20
1344 SeRenDIP-CE: Sequence-based Interface Prediction for Conformational Epitopes
Hou, Q.; Stringer, B.; Waury, K.; Capel, H.; Haydarlou, R.; Abeln, S.; Heringa, J.; Feenstra, K. A.
10.1101/2020.11.19.390500 — bioinformatics — Posted on 2020-11-20
1346 Interactive design of GPU-accelerated Image Data Flow Graphs and cross-platform deployment using multi-lingual code generation
Haase, R.; Jain, A.; Rigaud, S.; Vorkel, D.; Rajasekhar, P.; Suckert, T.; Lambert, T. J.; Nunez-Iglesias, J.; Poole, D. P.; Tomancak, P.; Myers, E. W.
10.1101/2020.11.19.386565 — bioinformatics — Posted on 2020-11-20
1347 Efficient and precise single-cell reference atlas mapping with Symphony
Kang, J. B.; Nathan, A.; Millard, N.; Rumker, L.; Moody, D. B.; Korsunsky, I.; Raychaudhuri, S.
10.1101/2020.11.18.389189 — bioinformatics — Posted on 2020-11-20
1349 piNET: An Automated Proliferation Index Calculator Framework for Ki67 Breast Cancer Images
Geread, R. S.; Sivanandarajah, A.; Brouwer, E.; Wood, G.; Androutsos, D.; Faragalla, H.; Khademi, A.
10.1101/2020.11.19.390401 — bioinformatics — Posted on 2020-11-20
1355 Preliminary Minimum Reporting Requirements for Reporting In-Vivo Neural Interface Research: I. Implantable Neural Interfaces
Eiber, C. D.; Delbeke, J.; Cardoso, J.; de Neeling, M.; John, S.; Lee, C. W.; Skefos, J.; Sun, A.; Prodanov, D.; McKinney, Z.
10.1101/2020.11.18.375741 — bioengineering — Posted on 2020-11-20
1360 Bivariate genomic prediction of phenotypes by selecting epistatic interactions across years
Vojgani, E.; Pook, T.; Hoelker, A. C.; Mayer, M.; Schoen, C. C.; Simianer, H.
10.1101/2020.11.18.388330 — genetics — Posted on 2020-11-20
1361 Mono- and bi-allelic protein truncating variants in alpha-actinin 2 cause cardiomyopathy through distinct mechanisms
Lindholm, M. E.; Jimenez-Morales, D.; Zhu, H.; Seo, K.; Amar, D.; Zhao, C.; Raja, A.; Madhvani, R.; Espenel, C.; Sutton, S.; Caleshu, C.; Berry, G. J.; Motonaga, K. S.; Dunn, K.; Platt, J.; Ashley, E.; Wheeler, M. T.
10.1101/2020.11.19.389064 — genetics — Posted on 2020-11-20
1365 A scalable method for identifying recombinants from unaligned sequences
Feng, Q.; Tiedje, K.; Ruybal-Pesantez, S.; Tonkin-Hill, G.; Duffy, M.; Day, K.; Shim, H.; Chan, Y.-b.
10.1101/2020.11.18.389262 — evolutionary biology — Posted on 2020-11-20
1368 Loss of active neurogenesis in the adult shark retina
Hernandez-Nunez, I.; Robledo, D.; Mayeur, H.; Mazan, S.; Sanchez, L.; Adrio, F.; Barreiro-Iglesias, A.; Candal, E.
10.1101/2020.11.19.389973 — developmental biology — Posted on 2020-11-20
1369 Transcriptional regulation of EMT by nuclear MMP28
GOUIGNARD, N.; BIBONNE, A.; SAINT-JEANNET, J.-P.; THEVENEAU, E.
10.1101/2020.11.19.389544 — developmental biology — Posted on 2020-11-20
1373 Proteomics on longitudinal serum samples differentiates localized and disseminated Lyme disease
Fatou, B.; Smolen, K. K.; Belperron, A. A.; Wurie, Z.; Kleinstein, S.; Montgomery, R.; Levy, O.; Bockenstedt, L. K.; Steen, H.
10.1101/2020.11.18.387993 — immunology — Posted on 2020-11-20
1374 Preclinical validation of a second generation leishmanization vaccine against vector transmitted fatal visceral leishmaniasis
Nakhasi, H. L.; DEY, R.; Gannavaram, S.; Karmakar, S.; Bhattacharya, P.; Ismail, N.; Satoskar, A.; Volpedo, G.; Oliveira, L. F.; Oristian, J.; Meneses, C.; Valenzuela, J. G.; Kamhawi, S.; Zhang, W. W.; Matlashewski, G.; Hamano, S.; Satoskar, M.; Satoskar, S.; Sastry, R. M.; Kaviraj, S.; Singh, S.; Singh, K. P.; Das, S.; Das, P.; Mondal, A.; Pandey, K.
10.1101/2020.11.18.388553 — immunology — Posted on 2020-11-20
1375 Bacterial inhibition of CD8+ T-cells mediated cell death promotes neuroinvasion and within-host persistence
Maudet, C.; Kheloufi, M.; Levallois, S.; Gaillard, J.; Huang, L.; Gaultier, C.; Tsai, Y.-H.; Disson, O.; Lecuit, M.
10.1101/2020.11.20.384974 — immunology — Posted on 2020-11-20
1376 Precise spatiotemporal control of voltage-gated sodium channels by photocaged saxitoxin
Elleman, A. V.; Devienne, G.; Makinson, C. D.; Haynes, A. L.; Huguenard, J. R.; Du Bois, J.
10.1101/2020.11.18.389130 — neuroscience — Posted on 2020-11-20
1381 Mapping the common and distinct neural correlates of visual, rule and motor conflict
Goulding Mew, B.; Custovic, D.; Soreq, E.; Lorenz, R.; Violante, I. R.; Sandrone, S.; Hampshire, A.
10.1101/2020.11.19.388231 — neuroscience — Posted on 2020-11-20
1383 Migraine Attacks as a Result of Hypothalamic Loss of Control
Stankewitz, A.; Keidel, L.; Rehm, M.; Irving, S.; Kaczmarz, S.; Preibisch, C.; Witkovsky, V.; Zimmer, C.; Schulz, E.; Toelle, T. R.
10.1101/2020.11.19.390104 — neuroscience — Posted on 2020-11-20
1389 The ant fungus garden acts as an external digestive system
Caraballo-Rodriguez, A. M.; Pucket, S. P.; Kyle, K. E.; Petras, D.; da Silva, R. R.; Nothias, L.-F.; Ernst, M.; van der Hooft, J. J. J.; Tripathi, A.; Wang, M.; Balunas, M. J.; Klassen, J. L.; Dorrestein, P. C.
10.1101/2020.11.18.389361 — systems biology — Posted on 2020-11-20
1390 Ancestral class-promiscuity as a driver of functional diversity in the BAHD acyltransferase family in plants
Kruse, L. H.; Weigle, A. T.; Martinez-Gomez, J.; Chobirko, J. D.; Schaffer, J. E.; Bennett, A. A.; Specht, C. D.; Jez, J. M.; Shukla, D.; Moghe, G. D.
10.1101/2020.11.18.385815 — plant biology — Posted on 2020-11-20
1391 Divergence in a stress-associated gene regulatory network underlies differential growth control in the Brassicaceae family
Sun, Y.; Oh, D.-H.; Duan, L.; Ramachandran, P.; Ramirez, A.; Bartlett, A.; Dassanayake, M.; Dinneny, J. R.
10.1101/2020.11.18.349449 — plant biology — Posted on 2020-11-20
1393 Diet and heat - one neuronal subset two responses
Prince, E.; Kretzschmar, J.; Trautenberg, L. C.; Brankatschk, M.
10.1101/2020.11.18.388017 — physiology — Posted on 2020-11-20
1395 Effects of Endogenous Angiotensin II on Abdominal Aortic Aneurysms and Atherosclerosis in Angiotensin II-infused Mice
Kukida, M.; Sawada, H.; Ohno-Urabe, S.; Howatt, D. A.; Moorleghen, J. J.; Poglitsch, M.; Daugherty, A.; Lu, H. S.
10.1101/2020.11.18.377416 — pathology — Posted on 2020-11-20
1397 Doxycycline interferes with tau amyloid aggregation abolishing its associated neuronal toxicity
Medina, L.; Gonzalez Lizarraga, F.; Dominguez Meijide, A.; Ploper, D.; Parrales, V.; Sequeira, S.; Cima Omorri, M. S.; Zweckstetter, M.; del Bel, E.; Michel, P. P.; Fleming Outeiro, T.; Raisman-Vozari, R.; Chehin, R. N.; Socias, S. B.
10.1101/2020.11.18.388561 — biophysics — Posted on 2020-11-20
1402 Cas12a-Capture: a novel, low-cost, and scalable method for targeted sequencing
Mighell, T. L.; Nishida, A.; O'Connell, B. L.; Miller, C. V.; Grindstaff, S.; Thornton, C. A.; Adey, A. C.; Doherty, D.; O'Roak, B. J.
10.1101/2020.11.18.388876 — genomics — Posted on 2020-11-20
1404 Taxonomic sampling and rare genomic changes overcome long-branch attraction in the phylogenetic placement of pseudoscorpions
Ontano, A. Z.; Gainett, G.; Aharon, S.; Ballesteros, J. A.; Benavides, L. R.; Corbett, K. F.; Gavish-Regev, E.; Harvey, M. S.; Monsma, S.; Santibanez-Lopez, C. E.; Setton, E. V.; Zehms, J. T.; Zeh, J. A.; Zeh, D. W.; Sharma, P. P.
10.1101/2020.11.18.389098 — evolutionary biology — Posted on 2020-11-20
1405 Two new hybrid zones expand the swordtail hybridization model system
Powell, D. L.; Moran, B.; Kim, B.; Banerjee, S. M.; Aguillon, S. M.; Fascinetto-Zago, P.; Langdon, Q.; Schumer, M.
10.1101/2020.11.18.389205 — evolutionary biology — Posted on 2020-11-20
1406 Dehydration risk, not ambient incubation, limits nest attendance at high temperatures
Bourne, A. R.; Ridley, A. R.; Mckechnie, A. E.; Spottiswoode, C. N.; Cunningham, S. J.
10.1101/2020.11.18.388025 — ecology — Posted on 2020-11-20
1409 Repeated blast mild traumatic brain injury and oxycodone self-administration produce interactive effects on neuroimaging outcomes
Muelbl, M. J.; Glaeser, B.; Shah, A. S.; Chiariello, R.; Nawarawong, N. N.; Stemper, B. D.; Budde, M. D.; Olsen, C. M.
10.1101/2020.11.18.388421 — neuroscience — Posted on 2020-11-20
1412 Tension-dependent stabilization of E-cadherin limits cell-cell contact expansion
Slovakova, J.; Sikora, M.; Caballero-Mancebo, S.; Krens, G. S.; Heisenberg, C.-P.; Kaufmann, W. A.; Huljev, K.
10.1101/2020.11.20.391284 — cell biology — Posted on 2020-11-20
1414 Adipose Triglyceride Lipase protects the endocytosis of renal cells on a high fat diet in Drosophila
Lubojemska, A.; Stefana, M. I.; Lampe, L.; Yoshimura, A.; Burrell, A.; Collinson, L.; Gould, A. P.
10.1101/2020.11.19.390146 — cell biology — Posted on 2020-11-20
1416 ATP triggers macropinocytosis that internalizes and is regulated by PANX1
Boyce, A. K.; van der Slagt, E.; Sanchez-Arias, J. C.; Swayne, L. A.
10.1101/2020.11.19.389072 — cell biology — Posted on 2020-11-20
1417 Unscheduled origin building in S-phase upon tight CDK1 inhibition suppresses CFS instability
BRISON, O.; Gnan, S.; Azar, D.; Schmidt, M.; KOUNDRIOUKOFF, S.; El-Hilali, S.; Jaszczyszyn, Y.; Lachages, A.-M.; Thermes, C.; Chen, C.-L.; Debatisse, M.
10.1101/2020.11.19.390054 — cell biology — Posted on 2020-11-20
1418 A conserved ubiquitin- and ESCRT-dependent pathway to regulate human lysosomal membrane proteins
Zhang, W.; Yang, X.; Chen, L.; Liu, Y.-Y.; Venkatarangan, V.; Reist, L.; Hanson, P.; Xu, H.; Wang, Y.; Li, M.
10.1101/2020.11.18.389296 — cell biology — Posted on 2020-11-20
1419 AI-Driven Multiscale Simulations Illuminate Mechanisms of SARS-CoV-2 Spike Dynamics
Casalino, L.; Dommer, A. C.; Gaieb, Z.; Barros, E. P.; Sztain, T.; Ahn, S.-H.; Trifan, A.; Brace, A.; Ma, H.; Lee, H.; Turilli, M.; Bogetti, A.; Khalid, S.; Chong, L.; Simmerling, C.; Hardy, D.; Maia, J.; Phillips, J.; Kurth, T.; Stern, A.; Huang, L.; McCalpain, J.; Tatineni, M.; Gibbs, T.; Stone, J. E.; Jha, S.; Ramanathan, A.; Amaro, R. E.
10.1101/2020.11.19.390187 — biophysics — Posted on 2020-11-20
1421 Fibroblastic Reticular Cell Response to Dendritic Cells Requires Coordinated Activity of Podoplanin, CD44 and CD9
de Winde, C. M.; Makris, S.; Millward, L.; Cantoral, J.; Benjamin, A. C.; Martinez, V. G.; Acton, S. E.
10.1101/793141 — cell biology — Posted on 2020-11-20
1422 Anti-severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) potency of Mefloquine as an entry inhibitor in vitro
Shionoya, K.; Yamasaki, M.; Iwanami, S.; Ito, Y.; Fukushi, S.; Ohashi, H.; Saso, W.; Tanaka, T.; Aoki, S.; Kuramochi, K.; Iwami, S.; Takahashi, Y.; Suzuki, T.; Muramatsu, M.; Takeda, M.; Wakita, T.; Watashi, K.
10.1101/2020.11.19.389726 — microbiology — Posted on 2020-11-20
1423 Highly potent anti-SARS-CoV-2 multi-DARPin therapeutic candidates
Walser, M.; Rothenberger, S.; Hurdiss, D. L.; Schlegel, A.; Calabro, V.; Fontaine, S.; Villemagne, D.; Paladino, M.; Hospodarsch, T.; Neculcea, A.; Cornelius, A.; Schildknecht, P.; Matzner, M.; Haenggi, M.; Franchini, M.; Kaufmann, Y.; Schaible, D.; Schlegel, I.; Iss, C.; Looser, T.; Mangold, S.; Herzog, C.; Schiegg, D.; Reichen, C.; Radom, F.; Bosshart, A.; Lehmann, A.; Haeuptle, M. A.; Zuercher, A.; Vagt, T.; Sigrist, G.; Straumann, M.; Proba, K.; Veitonmaki, N.; Dawson, K. M.; Zitt, C.; Mayor, J.; Ryter, S.; Lyoo, H.; Wang, C.; Li, W.; Drulyte, I.; Du, W.; Binz, H. K.; de Waal, L.; Stittela
10.1101/2020.08.25.256339 — immunology — Posted on 2020-11-20
1424 Multiscale three-dimensional pathology findings of COVID-19 diseased lung using high-resolution cleared tissue microscopy
Li, G.; Fox, S. E.; Summa, B.; Hu, B.; Wenk, C.; Akmatbekov, A.; Harbert, J. L.; Vander Heide, R. S.; Brown, J. Q.
10.1101/2020.04.11.037473 — pathology — Posted on 2020-11-20
1425 EcDNA hubs drive cooperative intermolecular oncogene expression
Hung, K. L.; Yost, K. E.; Xie, L.; Wu, S.; Lange, J. T.; Duffy, C. V.; Kraft, K.; Tang, J.; Shi, Q.; Rose, J. C.; Corces, M. R.; Granja, J. M.; Li, R.; Rajkumar, U.; Tjian, R.; Bafna, V.; Mischel, P. S.; Liu, Z.; Chang, H. Y.
10.1101/2020.11.19.390278 — cancer biology — Posted on 2020-11-20
1431 Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma
Vandeberg, P.; Cruz, M.; Diez, J. M.; Merritt, W. K.; Santos, B.; Trukawinski, S.; Wellhouse, A.; Jose, M.; Willis, T.
10.1101/2020.11.18.388991 — immunology — Posted on 2020-11-20
1432 Hypoxia triggers collective aerotactic migration in Dictyostelium discoideum
Cochet-Escartin, O.; Demircigil, M.; Hirose, S.; Allais, B.; Gonzalo, P.; Mikaelian, I.; Calvez, V.; Funamoto, K.; Anjard, C.; Rieu, J.-P.
10.1101/2020.08.17.246082 — biophysics — Posted on 2020-11-20
1434 Asymmetric outcome of community coalescence of seed and soil microbiota during early seedling growth
Rochefort, A.; Simonin, M.; Marais, C.; Guillerm-Erckelboudt, A.-Y.; Barret, M.; Sarniguet, A.
10.1101/2020.11.19.390344 — microbiology — Posted on 2020-11-20
1435 NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Ong, C. E. B.; Patchett, A. L.; Darby, J. M.; Chen, J.; Liu, G.-S.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2020.09.06.274720 — immunology — Posted on 2020-11-20
1437 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Cappucci, U.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-20
1440 Overlapping neural representations for the position of visible and imagined objects
Robinson, A. K.; Grootswagers, T.; Shatek, S. M.; Gerboni, J.; Holcombe, A. O.; Carlson, T. A.
10.1101/2020.03.02.974162 — neuroscience — Posted on 2020-11-20
1443 A single cell view of the transcriptome during lateral root initiation in Arabidopsis thaliana
Gala, H. P.; Lanctot, A. P.; Jean-Baptiste, K.; Guiziou, S.; Chu, J. C.; Zemke, J. E.; George, W.; Queitsch, C.; Cuperus, J.; Nemhauser, J.
10.1101/2020.10.02.324327 — plant biology — Posted on 2020-11-20
1444 YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.
10.1101/372524 — cancer biology — Posted on 2020-11-20
1445 GNS561, a clinical-stage PPT1 inhibitor, is efficient against hepatocellular carcinoma via modulation of lysosomal functions
BRUN, S.; Raymond, E.; Bassissi, F.; Jilkova, Z. M.; Mezouar, S.; Rachid, M.; Novello, M.; Tracz, J.; Hamai, A.; Lalmanach, G.; Vanderlynden, L.; Bestion, E.; Legouffe, R.; Stauber, J.; Schubert, T.; Plach, M. G.; Courcambeck, J.; Drouot, C.; Jacquemot, G.; Serdjebi, C.; Roth, G.; Baudoin, J.-P.; Ansaldi, C.; Decaens, T.; Halfon, P.
10.1101/2020.09.30.320010 — cancer biology — Posted on 2020-11-20
1446 Stromal Oncostatin M axis promotes breast cancer progression
Araujo, A. M.; Abaurrea, A.; Azcoaga, P.; Lopez-Velazco, J. I.; Rezola, R.; Osorio-Querejeta, I.; Valdes-Mora, F.; Flores, J. M.; Jenkins, L.; Fernandez-Nogueira, P.; Ferrari, N.; Martin-Martin, N.; Tzankov, A.; Eppenberger-Castori, S.; Alvarez-Lopez, I.; Urruticoechea, A.; Bragado, P.; Coleman, N.; Carracedo, A.; Gallego-Ortega, D.; Calvo, F.; Isacke, C. M.; Caffarel, M. M.; Lawrie, C. H.
10.1101/2020.10.30.356774 — cancer biology — Posted on 2020-11-20
1451 Transcriptional kinetics and molecular functions of long non-coding RNAs
Johnsson, P. A.; Ziegenhain, C.; Hartmanis, L.; Hendriks, G.-J.; Hagemann-Jensen, M.; Reinius, B.; Sandberg, R.
10.1101/2020.05.05.079251 — genomics — Posted on 2020-11-20
1452 Does diversity beget diversity in microbiomes?
Madi, N. J.; Vos, M.; Murall, C. L.; Legendre, P.; Shapiro, B. J.
10.1101/612739 — evolutionary biology — Posted on 2020-11-20
1454 The avian W chromosome is a refugium for endogenous retroviruses with likely effects on female-biased mutational load and genetic incompatibilities
Peona, V.; Palacios-Gimenez, O. M.; Blommaert, J.; Liu, J.; Haryoko, T.; Jonsson, K. A.; Irestedt, M.; Zhou, Q.; Jern, P.; Suh, A.
10.1101/2020.07.31.230854 — evolutionary biology — Posted on 2020-11-20
1455 Quantitative Mapping of Human Hair Graying and Reversal in Relation to Life Stress
Rosenberg, A.; Rausser, S.; Ren, J.; Mosharov, E.; Sturm, G. M.; Ogden, R. T.; Patel, P.; Soni, R. K.; Lacefield, C.; Tobin, D. J.; Paus, R.; Picard, M.
10.1101/2020.05.18.101964 — cell biology — Posted on 2020-11-20
1456 Adherent cell remodeling on micropatterns is modulated by Piezo1 channels
Jetta, D.; Bahrani Fard, M. R.; Sachs, F.; Munechika, K.; Hua, S. Z.
10.1101/2020.11.18.389106 — biophysics — Posted on 2020-11-20
1457 dsSwissKnife: An R package for federated data analysis
Dragan, I.; Sparso, T.; Kuznetsov, D.; Slieker, R.; Ibberson, M.
10.1101/2020.11.17.386813 — bioinformatics — Posted on 2020-11-20
1460 A Structural Signature Motif Enlightens the Origin and Diversification of Nuclear Receptors
Beinsteiner, B.; Markov, G. V.; Erb, S.; Chebaro, Y.; McEwen, A. G.; Sanglier Cianferani, S.; Laudet, V.; Moras, D.; Billas, I.
10.1101/2020.11.18.388405 — evolutionary biology — Posted on 2020-11-20
1463 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-20
1465 U-Net Model for Brain Extraction on Non-human Primates
Wang, X.; Li, X.-H.; Cho, J. W.; Russ, B.; Rajamani, N.; Omelchenko, A.; Ai, L.; Korchmaros, A.; Garcia-Saldivar, P.; Wang, Z.; Kalin, N. H.; Schroeder, C. E.; Craddock, R. C.; Fox, A. S.; Evans, A. C.; Messinger, A.; Milham, M. P.; Xu, T.
10.1101/2020.11.17.385898 — neuroscience — Posted on 2020-11-20
1466 Rotational dynamics in motor cortex are consistent with a feedback controller
Kalidindi, H. T.; Cross, K. P.; Lillicrap, T. P.; Omrani, M.; Falotico, E.; Sabes, P. N.; Scott, S. H.
10.1101/2020.11.17.387043 — neuroscience — Posted on 2020-11-20
1467 Time-Encoding Migrates from Prefrontal Cortex to Dorsal Striatum During Learning of a Self-Timed Response Duration Task
Chiuffa Tunes, G.; de Oliveira, E. F.; Vieira, E. U. P.; Caetano, M. S.; Cravo, A. M.; Reyes, M. B.
10.1101/2020.11.19.390286 — neuroscience — Posted on 2020-11-20
1468 The human hippocampus plays a time-limited role in retrieving autobiographical memories
Gilmore, A. W.; Quach, A.; Kalinowski, S. E.; Gonzalez-Araya, E. I.; Gotts, S. J.; Schacter, D. L.; Martin, A.
10.1101/2020.11.19.390526 — neuroscience — Posted on 2020-11-19
1469 Aberrant gliogenesis and excitation in MEF2C autism patient hiPSC-neurons and cerebral organoids
Trudler, D.; Ghatak, S.; Parker, J.; Talantova, M.; Grabauskas, T.; Noveral, S. M.; Teranaka, M.; Luevanos, M.; Dolatabadi, N.; Bakker, C.; Lopez, K.; Sultan, A.; Chan, A.; Choi, Y.; Kawaguchi, R.; Schork, N.; Stankiewicz, P.; Garcia-Bassets, I.; Kozbial, P.; Rosenfeld, M. G.; Nakanishi, N.; Geschwind, D.; Chan, S. F.; Ambasudhan, R.; Lipton, S. A.
10.1101/2020.11.19.387639 — neuroscience — Posted on 2020-11-19
1471 Oscillatory responses to generated and perceived rhythms
Ostarek, M.; Alday, P. M.; Gawel, O.; Wolfgruber, J.; Knudsen, B.; Mantegna, F.; Huettig, F.
10.1101/2020.11.19.390062 — neuroscience — Posted on 2020-11-19
1473 MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML
Goveas, N.; Waskow, C.; Arndt, K.; Heuberger, J.; Zhang, Q.; Alexopoulou, D.; Dahl, A.; Birchmeier, W.; Anastassiadis, K.; Stewart, A. F.; Kranz, A.
10.1101/2020.11.19.389528 — genetics — Posted on 2020-11-19
1482 Hundreds of nuclear and plastid loci yield insights into orchid relationships
Perez-Escobar, O. A.; Dodsworth, S.; Bogarin, D.; Bellot, S.; Balbuena, J. A.; Schley, R.; Kikuchi, I.; Morris, S. K.; Epitawalage, N.; Cowan, R.; Maurin, O.; Zuntini, A.; Arias, T.; Serna, A.; Gravendeel, B.; Torres, M. F.; Nargar, K.; Chomicki, G.; Chase, M.; Leitch, I. J.; Forest, F.; Baker, W. J.
10.1101/2020.11.17.386508 — evolutionary biology — Posted on 2020-11-19
1487 Chemoproteomics Maps Glycolytic Targetome in Cancer Cells
Tian, Y.; Wan, N.; Ding, M.; Shao, C.; Wang, N.; Bao, Q.; Lu, W.; Hu, H.; Sun, H.; Yang, C.; Zhou, K.; Chen, S.; Wang, G.; Ye, H.; Hao, H.
10.1101/2020.11.18.387670 — cancer biology — Posted on 2020-11-19
1490 Signatures Of TSPAN8 Variants Associated With Human Metabolic Regulation And Diseases
De, T.; Goncalves, A.; Speed, D.; Froguel, P.; NFBC Consortium, ; Gaffney, D.; Johnson, M. R.; Jarvelin, M.-R.; Coin, L.
10.1101/2020.11.17.386839 — genomics — Posted on 2020-11-19
1491 Fast neutron mutagenesis in soybean creates frameshift mutations
Wyant, S. R.; Rodriguez, M. F.; Carter, C. K.; Parrott, W. A.; Jackson, S. A.; Stupar, R. M.; Morrell, P. L.
10.1101/2020.11.17.387373 — genetics — Posted on 2020-11-19
1494 Generation of two Multipotent Mesenchymal Progenitor Cell Lines Capable of Osteogenic, Mature Osteocyte, Adipogenic, and Chondrogenic Differentiation
Prideaux, M.; Wright, C. S.; Noonan, M. L.; Yi, X.; Clinkenbeard, E. L.; Mevel, E.; Wheeler, J. A.; Byers, S.; Sankar, U.; White, K. E.; Atkins, G. J.; Thompson, W. R.
10.1101/2020.11.19.385138 — cell biology — Posted on 2020-11-19
1495 Type I PRMTs and PRMT5 Independently Regulate Both snRNP Arginine Methylation and Post-Transcriptional Splicing
Maron, M. I.; Burgos, E. S.; Gupta, V.; Casill, A. D.; Kosmyna, B.; Chen, H.; Gamble, M. J.; Query, C. C.; Shechter, D.
10.1101/2020.11.18.389288 — cell biology — Posted on 2020-11-19
1496 Cis regulation within a cluster of viral microRNAs
Vilimova, M.; Contrant, M.; Randrianjafy, R.; Dumas, P.; Pfeffer, S.; Fender, A.
10.1101/2020.11.19.389551 — molecular biology — Posted on 2020-11-19
1497 A human stem cell-derived neurosensory-epithelial circuitry on-a-chip to model herpes simplex virus reactivation
Mazzara, P. G.; Criscuolo, E.; Rasponi, M.; Massimino, L.; Muggeo, S.; Palma, C.; Castelli, M.; Clementi, M.; Burioni, R.; Mancini, N.; Broccoli, V.; Clementi, N.
10.1101/2020.11.19.390260 — microbiology — Posted on 2020-11-19
1499 Bat influenza vectored NS1-truncated live vaccine protects pigs against heterologous virus challenge
Lee, J.; Li, Y.; Li, Y.; Cino-Ozuna, G.; Duff, M.; Lang, Y.; Ma, J.; Sunwoo, S.; Richt, J. A.; Ma, W.
10.1101/2020.11.18.389254 — microbiology — Posted on 2020-11-19
1500 Selective vulnerability of supragranular layer neurons in schizophrenia
Batiuk, M. Y.; Tyler, T.; Mei, S.; Rydbirk, R.; Petukhov, V.; Sedmak, D.; Frank, E.; Feher, V.; Habek, N.; Hu, Q.; Igolkina, A.; Roszik, L.; Pfisterer, U.; Petanjek, Z.; Adorjan, I.; Kharchenko, P. V.; Khodosevich, K.
10.1101/2020.11.17.386458 — neuroscience — Posted on 2020-11-19
1502 Temporal dynamics of implicit memory underlying serial dependence
Bilacchi, C. M.; Sirius, E. V. P.; Cravo, A. M.; de Azevedo Neto, R. M.
10.1101/2020.11.17.386821 — neuroscience — Posted on 2020-11-19
1503 Targeted memory reactivation of a serial reaction time task in SWS, but not REM, preferentially benefits the non-dominant hand
Koopman, A. C. M.; Abdellahi, M. E. A.; Belal, S.; Rakowska, M.; Metcalf, A.; Sledziowska, M.; Hunter, T.; Lewis, P.
10.1101/2020.11.17.381913 — neuroscience — Posted on 2020-11-19
1514 Magnaporthe oryzae populations in Sub-Saharan Africa are diverse and show signs of local adaptation
Onaga, G.; Suktrakul, W.; Wanjiku, M.; Quibod, I. L.; Domelevo Entfellner, J.-B.; Bigirimana, J.; Habarugira, G.; Murori, R.; Asea, G.; Ismail, A. M.; Jantasuriyarat, C.; Oliva, R.
10.1101/2020.11.17.377325 — genomics — Posted on 2020-11-19
1517 Transgenerational Regulation of Sexual Attractiveness in C. elegans Nematodes
Toker, I. A.; Lev, I.; Mor, Y.; Gurevich, Y.; Fisher, D.; Houri-Zeevi, L.; Antonova, O.; Hadany, L.; Shaham, S.; Rechavi, O.
10.1101/2020.11.18.389387 — molecular biology — Posted on 2020-11-19
1518 A Low-Cost Mass Spectrometry-Based Approach for Quantifying Purines in Placental Extracts
Rodriguez, R.; Konovets, I.; Ralchenko, S.; Kharkhota, M.; Kostyuk, A.; Kosach, V.; Voronina, I.; Filimonova, N.; Obolenskaya, M. Y.
10.1101/2020.11.19.389817 — molecular biology — Posted on 2020-11-19
1519 Microbial Metagenomic Approach Uncovers the First Rabbit Haemorrhagic Disease Virus genome in Sub-Saharan Africa
Happi, A. N.; Ogunsanya, O. A.; Oguzie, J.; Oluniyi, P. E.; Olono, A. S.; Heeney, J. L.; Happi, C.
10.1101/2020.11.19.390559 — molecular biology — Posted on 2020-11-19
1522 Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa
Abisado, R.; Kimbrough, J. H.; McKee, B. M.; Craddock, V.; Smalley, N. E.; Dandekar, A. A.; Chandler, J. R.
10.1101/2020.11.15.383836 — microbiology — Posted on 2020-11-19
1523 Reprogrammed CRISPR-Cas13b suppresses SARS-CoV-2 replication and circumvents its mutational escape through mismatch tolerance
Fareh, M.; Zhao, W.; Hu, W.; Casan, J. M.; Kumar, A.; Symons, J.; Voskoboinik, I.; Ekert, P. G.; Rudraraju, R.; Lewin, S. R.; Trapani, J. A.
10.1101/2020.11.18.389312 — microbiology — Posted on 2020-11-19
1524 Asymmetric outcome of community coalescence of seed and soil microbiota during early seedling growth
Sarniguet, A.; Rochefort, A.; Simonin, M.; Marais, C.; Guillerm-Erckelboudt, A.-Y.; Barret, M.
10.1101/2020.11.19.390344 — microbiology — Posted on 2020-11-19
1526 HTT silencing delays onset and slows progression of Huntington disease like phenotype: Monitoring with a novel neurovascular biomarker
Liu, H.; Zhang, C.; Xu, J.; Jin, J.; Cheng, l.; Wu, Q.; Wei, Z.; Liu, P.; Lu, H.; van Zijl, P.; Ross, C. A.; Hua, J.; Duan, W.
10.1101/2020.11.17.386631 — neuroscience — Posted on 2020-11-19
1527 Chondroitinase and antidepressants promote plasticity by releasing TRKB from dephosphorylating control of PTPσ in parvalbumin neurons
Lesnikova, A.; Casarotto, P. C.; Fred, M. S.; Voipio, M.; Winkel, F.; Steinzeig, A.; Antila, H.; Umemori, J.; Biojone, C.; Castren, E.
10.1101/2020.08.13.249615 — neuroscience — Posted on 2020-11-19
1528 Inhibition of VCP preserves retinal structure and function in autosomal dominant retinal degeneration
Arango-Gonzalez, B.; Sen, M.; Guarascio, R.; Ziaka, K.; del Amo, E. M.; Hau, K.; Poultney, H.; Asfahani, R.; Urtti, A.; Chou, T.-F.; Bolz, S.; Deshaies, R. J.; Haq, W.; Cheetham, M. E.; Ueffing, M.
10.1101/2020.11.17.384669 — neuroscience — Posted on 2020-11-19
1530 Sex-specific classification of drug-induced Torsade de Pointes susceptibility using cardiac simulations and machine learning
Fogli Iseppe, A.; Ni, H.; Zhu, S.; Zhang, X.; Coppini, R.; Yang, P.-C.; Srivatsa, U.; Clancy, C. E.; Edwards, A. G.; Morotti, S.; Grandi, E.
10.1101/2020.10.26.352740 — pharmacology and toxicology — Posted on 2020-11-19
1532 Cross-Tissue Transcriptomic Analysis Leveraging Machine Learning Approaches Identifies New Biomarkers for Rheumatoid Arthritis
Rychkov, D.; Neely, J.; Oskotsky, T.; Yu, S.; Perlmutter, N.; Nititham, J.; Carvidi, A.; Krueger, M.; Gross, A. J.; Criswell, L. A.; Ashouri, J. F.; Sirota, M.
10.1101/2020.07.24.220483 — bioinformatics — Posted on 2020-11-19
1533 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2020-11-19
1535 Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse neocortex
Liang, L.; Fazel Darbandi, S.; Pochareddy, S.; Gulden, F. O.; Gilson, M. C.; Sheppard, B. K.; Sahagun, A.; An, J.-Y.; Werling, D. M.; Rubenstein, J. L. R.; Sestan, N.; Bender, K.; Sanders, S. J.
10.1101/2020.11.18.389171 — genetics — Posted on 2020-11-19
1538 VTAM: A robust pipeline for validating metabarcoding data using internal controls
Gonzalez, A.; Dubut, V.; Corse, E.; Mekdad, R.; Dechatre, T.; Meglecz, E.
10.1101/2020.11.06.371187 — ecology — Posted on 2020-11-19
1542 Loss of integration of brain networks after sleep deprivation relates to the worsening of cognitive functions
Pesoli, M.; Rucco, R.; Liparoti, M.; Lardone, A.; D'Aurizio, G.; Minino, R.; Troisi Lopez, E.; Paccone, A.; Granata, C.; Mandolesi, L.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.07.15.197590 — neuroscience — Posted on 2020-11-19
1543 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Cappucci, U.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-19
1544 Epitomic analysis of the specificity of conformation-dependent, anti-aβ amyloid monoclonal antibodies
Reyes-Ruiz, J. M.; Nakajima, R.; Baghallab, I.; Goldschmidt, L.; Sosna, J.; Ho, P. N. M.; Kumosani, T.; Felgner, P. L.; Glabe, C. G.
10.1101/2020.08.05.238105 — neuroscience — Posted on 2020-11-19
1546 Natural deletions in the SARS-CoV-2 spike glycoprotein drive antibody escape
McCarthy, K. R.; Rennick, L. J.; Nambulli, S.; Robinson-McCarthy, L. R.; Bain, W. G.; Haidar, G.; Duprex, W. P.
10.1101/2020.11.19.389916 — microbiology — Posted on 2020-11-19
1547 SARS-CoV-2 infection suppresses ACE2 function and antiviral immune response in the upper respiratory tract of infected patients
Gutierrez-Chamorro, L.; Riveira-Munoz, E.; Barrios, C.; Palau, V.; Massanella, M.; Garcia-Vidal, E.; Badia, R.; Pedreno, S.; Senserrich, J.; Rodriguez, E.; Clotet, B.; Cabrera, C.; Mitja, O.; Crespo, M.; Pascual, J.; Riera, M.; Ballana, E.
10.1101/2020.11.18.388850 — immunology — Posted on 2020-11-19
1549 Common allotypes of ER aminopeptidase 1 have substrate- dependent and highly variable enzymatic properties
Jonathan, H. P.; Temponeras, I.; Kuiper, J.; Cortes, A.; Korczynska, J.; Kitchen, S.; Stratikos, E.
10.1101/2020.11.19.389403 — biochemistry — Posted on 2020-11-19
1550 Extracellular vesicles from human adipose stem cells are neuroprotective after stroke in rats
Rohden, F.; Teixeira, L. V.; Bernardi, L. P.; Marques, N. P. F.; Colombo, M.; Teixeira, G. R.; de Oliveira, F. d. S.; Cirne Lima, E. O.; Guma, F. C. R.; Souza, D. O.
10.1101/2020.11.18.388355 — biochemistry — Posted on 2020-11-19
1551 Serine-ubiquitination regulates Golgi morphology and the secretory pathway upon Legionella infection
Liu, Y.; Mukherjee, R.; Bonn, F.; Colby, T.; Matic, I.; Glogger, M.; Heilemann, M.; Dikic, I.
10.1101/2020.07.27.223842 — cell biology — Posted on 2020-11-19
1553 Heritable Sexual Attraction under Parental Control
Toker, I. A.; Lev, I.; Mor, Y.; Gurevich, Y.; Fisher, D.; Houri-Zeevi, L.; Antonova, O.; Hadany, L.; Shaham, S.; Rechavi, O.
10.1101/2020.11.18.389387 — molecular biology — Posted on 2020-11-19
1554 TBPL2/TFIIA complex establishes the maternal transcriptome by an oocyte-specific promoter usage
Yu, C.; Cvetesic, N.; Hisler, V.; Gupta, K.; Ye, T.; Gazdag, E.; Negroni, L.; Hajkova, P.; Berger, I.; Lenhard, B.; Mueller, F.; Vincent, S. D.; Tora, L.
10.1101/2020.06.08.118984 — molecular biology — Posted on 2020-11-19
1556 Ngn2 induces diverse neuronal lineages from human pluripotency
Lin, H.-C.; He, Z.; Ebert, S.; Schörnig, M.; Santel, M.; Weigert, A.; Hevers, W.; Nadif Kasri, N.; Taverna, E.; Camp, J. G.; Treutlein, B.
10.1101/2020.11.19.389445 — neuroscience — Posted on 2020-11-19
1558 Transposable Element activation promotes neurodegeneration in a Drosophila model of Huntington's disease
Casale, A. M.; Liguori, F.; Ansaloni, F.; Finaurini, S.; Spirito, G.; Persichetti, F.; Sanges, R.; Gustincich, S.; Piacentini, L.
10.1101/2020.11.19.389718 — neuroscience — Posted on 2020-11-19
1560 Detecting SARS-CoV-2 variants with SNP genotyping
Harper, H.; Burridge, A. J.; Winfield, M.; Finn, A.; Davidson, A. D.; Matthews, D.; Hutchings, S.; Vipond, B.; Jain, N.; Edwards, K. J.; Barker, G.; The COVID-19 Genomics UK (COG-UK) consortium,
10.1101/2020.11.18.388140 — genomics — Posted on 2020-11-19
1561 MLL1 is required for maintenance of intestinal stem cells and the expression of the cell adhesion molecule JAML
Goveas, N.; Waskow, C.; Arndt, K.; Heuberger, J.; Zhang, Q.; Alexopoulou, D.; Dahl, A.; Birchmeier, W.; Anastassiadis, K.; Stewart, A. F.; Kranz, A.
10.1101/2020.11.19.389528 — genetics — Posted on 2020-11-19
1567 Dorsal Periaqueductal gray ensembles represent approach and avoidance states
Reis, F. M.; Lee, J. Y.; Maesta-Pereira, S.; Schuette, P. J.; Chakerian, M.; Liu, J.; La-Vu, M. Q.; Tobias, B. C.; Canteras, N.; Kao, J. C.; Adhikari, A.
10.1101/2020.11.19.389486 — neuroscience — Posted on 2020-11-19
1572 The chemotherapeutic drug methotrexate selects for antibiotic resistance
Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.
10.1101/2020.11.12.378059 — microbiology — Posted on 2020-11-19
1573 Visual effort moderates postural cascade dynamics
Mangalam, M.; Lee, I.-C.; Newell, K. M.; Kelty-Stephen, D. G.
10.1101/2020.07.17.209486 — neuroscience — Posted on 2020-11-19
1584 Structural Basis of Complex Formation Between Mitochondrial Anion Channel VDAC1 and Hexokinase-II
Haloi, N.; Wen, P.-C.; Cheng, Q.; Yang, M.; Natarajan, G.; Camara, A. K. S.; Kwok, W.-M.; Tajkhorshid, E.
10.1101/2020.11.18.365965 — biophysics — Posted on 2020-11-18
1585 Cell-to-cell heterogeneity in Sox2 and Brachyury expression guides progenitor destiny by controllingtheir movements.
Romanos, M.; Allio, G.; Combres, L.; Medevielle, F.; Escalas, N.; Soula, C.; Steventon, B.; Trescases, A.; Benazeraf, B.
10.1101/2020.11.18.388611 — developmental biology — Posted on 2020-11-18
1586 The centriolar satellite protein Cfap53/Ccdc11 facilitates the formation of the first zygotic microtubule organizing center in the zebrafish embryo.
Willekers, S.; Tessadori, F.; Vaart, B. v. d.; Henning, H. H. W.; Stucchi, R.; Altelaar, M.; Roelen, B. A. J.; Akhmanova, A.; Bakkers, J.
10.1101/2020.11.18.388652 — developmental biology — Posted on 2020-11-18
1587 The multi-scale architecture of mammalian sperm flagella and implications for ciliary motility
Leung, M. R.; Roelofs, M. C.; Ravi, R. T.; Maitan, P.; Henning, H.; Zhang, M.; Bromfield, E. G.; Howes, S. C.; Gadella, B. M.; Gadelha, H.; Zeev-Ben-Mordehai, T.
10.1101/2020.11.18.388975 — cell biology — Posted on 2020-11-18
1588 Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold
Schweizer, N.; Haren, L.; Viais, R.; Lacasa, C.; Dutto, I.; Merdes, A.; Luders, J.
10.1101/2020.11.18.384156 — cell biology — Posted on 2020-11-18
1589 High resolution 3D imaging of liver reveals a central role for subcellular architectural organization in metabolism
Parlakgul, G.; Arruda, A. P.; Cagampan, E.; Pang, S.; Guney, E.; Lee, Y.; Hess, H. F.; Xu, C. S.; Hotamisligil, G. S.
10.1101/2020.11.18.387803 — cell biology — Posted on 2020-11-18
1590 Biomarkers of lesion severity in a rodent model of nonarteritic anterior ischemic optic neuropathy (rNAION)
Guo, Y.; Mehabian, Z.; Johnson, M. A.; Miller, N. R.; Henderson, A.; Hamlyn, J.; Bernstein, S. L.
10.1101/2020.11.18.388132 — neuroscience — Posted on 2020-11-18
1591 Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries
Liang, Y.; Pividori, M.; Manichaikul, A.; Palmer, A. A.; Cox, N. J.; Wheeler, H. E.; Im, H. K.
10.1101/2020.11.12.373647 — genetics — Posted on 2020-11-18
1592 Reducing error and increasing reliability of wildlife counts from citizen science surveys: counting Weddell Seals in the Ross Sea from satellite images
Salas, L.; LaRue, M.; Nur, N.; Ainley, D.; Stammerjohn, S.; Pennycook, J.; Rotella, J.; Paterson, J. T.; Siniff, D.; Stamatiou, K.; Dozier, M.; Saints, J.; Barrington, L.
10.1101/2020.11.18.388157 — ecology — Posted on 2020-11-18
1593 Dysglycemia is associated with Mycobacterium tuberculosis lineages in tuberculosis patients of North Lima - Peru.
Lopez, K.; Arriaga, M. B.; Aliaga, J. G.; Barreda, N. N.; Sanabria, O. M.; Huang, C.-C.; Zhang, Z.; Garcia-de-la-Guarda, R.; Lecca, L.; Calcada Carvalho, A. C.; Kritski, A. L.; Calderon, R. I.
10.1101/2020.11.18.388124 — molecular biology — Posted on 2020-11-18
1594 A comprehensive map of genetic interactions in childhood cancer reveals multiple underlying biological mechanisms
Daub, J. T.; Amini, S.; Kersjes, D. J. E.; Ma, X.; Jäger, N.; Zang, J.; Pfister, S. M.; Holstege, F. C. P.; Kemmeren, P.
10.1101/2020.11.17.385120 — cancer biology — Posted on 2020-11-18
1596 Role of FMRP in rapid antidepressant effects and synapse regulation
Heaney, C. F.; Namjoshi, S. V.; Uneri, A.; Bach, E. C.; Weiner, J. L.; Raab-Graham, K. F.
10.1101/2020.08.25.266833 — molecular biology — Posted on 2020-11-18
1598 γ-secretase promotes postsynaptic maturation through the cleavage of a Wnt receptor
Restrepo, L.; DePew, A.; Moese, E.; Tymanskyj, S.; Parisi, M.; Aimino, M.; Duhart, J. C.; Fei, H.; Mosca, T. J.
10.1101/2020.11.18.387720 — neuroscience — Posted on 2020-11-18
1601 Transient genomic instability drives tumorigenesis through accelerated clonal evolution
Shoshani, O.; Bakker, B.; Wang, Y.; Kim, D. H.; Maldonado, M.; Demarest, M. A.; Artates, J.; Zhengyu, O.; Mark, A.; Wardenaar, R.; Sasik, R.; Spierings, D. C.; Vitre, B.; Fisch, K.; Foijer, F.; Cleveland, D. W.
10.1101/2020.11.17.387753 — cancer biology — Posted on 2020-11-18
1602 Methionine stress induces a ferroptotic gene signature in methionine dependent cancer cells
Wallis, K. F.; Bird, J. T.; Gies, A. J.; Mackintosh, S. G.; Tackett, A. J.; Byrum, S.; Miousse, I. R.
10.1101/2020.08.18.254490 — cancer biology — Posted on 2020-11-18
1603 CPEB2 m6A Methylation Regulates BTB Permeability via Affecting Splicing Factor SRSF5 Stability
zhang, m.; yang, c.; liu, x.; ruan, x.; wang, d.; liu, y.; cai, h.; zheng, j.; shao, l.; wang, p.; li, z.; yu, b.; XUE, Y.
10.1101/2020.11.17.387928 — cancer biology — Posted on 2020-11-18
1604 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-18
1606 Developmental dynamics of voltage-gated sodium channel isoform expression in the human and mouse neocortex
Liang, L.; Fazel Darbandi, S.; Pochareddy, S.; Gulden, F. O.; Gilson, M. C.; Sheppard, B. K.; Sahagun, A.; An, J.-Y.; Werling, D. M.; Rubenstein, J. L. R.; Sestan, N.; Bender, K.; Sanders, S. J.
10.1101/2020.11.18.389171 — genetics — Posted on 2020-11-18
1610 Universally available herbal teas based on sage and perilla elicit potent antiviral activity against SARS-CoV-2 in vitro
Le-Trilling, V. T. K.; Mennerich, D.; Schuler, C.; Flores-Martinez, Y.; Katschinski, B.; Dittmer, U.; Trilling, M.
10.1101/2020.11.18.388710 — microbiology — Posted on 2020-11-18
1611 Phylogenomics of 8,839 Clostridioides difficile genomes reveals recombination-driven evolution and diversification of toxin A and B
Mansfield, M. J.; Tremblay, B. J.-M.; Zeng, J.; Wei, X.; Hodgins, H.; Worley, J.; Bry, L.; Dong, M.; Doxey, A. C.
10.1101/2020.07.09.194449 — microbiology — Posted on 2020-11-18
1612 The ChiS family DNA-binding domain contains a cryptic helix-turn-helix variant
Klancher, C. A.; Minasov, G.; Podicheti, R.; Rusch, D. B.; Dalia, T. N.; Satchell, K. J.; Neiditch, M. B.; Dalia, A. B.
10.1101/2020.11.18.389122 — microbiology — Posted on 2020-11-18
1613 COVID-19-associated olfactory dysfunction reveals SARS-CoV-2 neuroinvasion and persistence in the olfactory system
De Melo, G. D.; Lazarini, F.; Levallois, S.; Hautefort, C.; Michel, V.; Larrous, F.; Verillaud, B.; Aparicio, C.; Wagner, S.; Gheusi, G.; Kergoat, L.; Kornobis, E.; Cokelaer, T.; Hervochon, R.; Madec, Y.; Roze, E.; Salmon, D.; Bourhy, H.; Lecuit, M.; Lledo, P.-M.
10.1101/2020.11.18.388819 — neuroscience — Posted on 2020-11-18
1614 Three major dimensions of human brain cortical ageing in relation to cognitive decline across the 8th decade of life.
Cox, S. R.; Harris, M. A.; Ritchie, S. J.; Buchanan, C. R.; Valdes Hernandez, M. d. C.; Corley, J.; Taylor, A. M.; Madole, J. W.; Harris, S. E.; Whalley, H. C.; McIntosh, A. M.; Russ, T. C.; Bastin, M. E.; Wardlaw, J. M.; Deary, I. J.; Tucker-Drob, E. M.
10.1101/2020.01.19.911420 — neuroscience — Posted on 2020-11-18
1615 Photostimulation of lymphatic clearance of red blood cells from the mouse brain after intraventricular hemorrhage
Li, D.; Liu, S.; Yu, T.; Liu, Z.; Sun, S.; Bragin, D.; Navolokin, N.; Kurths, J.; Semyachkina-Glushkovskaya, O. V.; Zhu, D.
10.1101/2020.11.16.384149 — neuroscience — Posted on 2020-11-18
1617 Severe childhood and adulthood stress associates with neocortical layer-specific reductions of mature spines in psychiatric disorders
Kaul, D.; Smith, C. C.; Stevens, J.; Frohlich, A. S.; Binder, E. B.; Mechawar, N.; Schwab, S. G.; Matosin, N.
10.1101/2020.08.31.276386 — neuroscience — Posted on 2020-11-18
1618 A genetic screen identifies dreammist as a regulator of sleep
Barlow, I. L.; Mackay, E.; Wheater, E.; Goel, A.; Lim, S.; Zimmerman, S.; Woods, I.; Prober, D. A.; Rihel, J.
10.1101/2020.11.18.388736 — neuroscience — Posted on 2020-11-18
1621 A Modular Workflow for Model Building, Analysis, and Parameter Estimation in Systems Biology and Neuroscience
Santos, J. P. G.; Pajo, K.; Trpevski, D.; Stepaniuk, A.; Eriksson, O.; Nair, A. G.; Keller, D.; Hellgren Kotaleski, J.; Kramer, A.
10.1101/2020.11.17.385203 — systems biology — Posted on 2020-11-18
1623 A Hybrid Cellular and Heterogeneous Catalyst Strategy for the Production of Olefins from Glucose
Wang, Z. Q.; Song, H.; Hara, N.; Park, D. S.; Kumar, G.; Min, Y.; Dauenhauer, P. J.; Chang, M. C. Y.
10.1101/2020.11.17.387563 — synthetic biology — Posted on 2020-11-18
1624 Transcriptome atlas of Phalaenopsis equestris
Klepikova, A. V.; Kasianov, A. S.; Ezhova, M. A.; Penin, A. A.; Logacheva, M. D.
10.1101/2020.11.03.366260 — plant biology — Posted on 2020-11-18
1627 Structural basis of ligand selectivity by a bacterial adhesin lectin involved in multi- species biofilm formation
Guo, S.; Vance, T.; Zahiri, H.; Eves, R.; Stevens, C.; Hehemann, J.-H.; Vidal-Melgosa, S.; Davies, P.
10.1101/2020.11.18.389155 — biochemistry — Posted on 2020-11-18
1628 Genome-wide maps of nucleolus interactions reveal distinct layers of repressive chromatin domains
Bersaglieri, C.; Kresoja-Rakic, J.; Gupta, S.; Baer, D.; Kuzyakiv, R.; Santoro, R.
10.1101/2020.11.17.386797 — genomics — Posted on 2020-11-18
1631 Molecular basis for inhibition of adhesin-mediated bacterial-host interactions through a novel peptide-binding domain
Guo, S.; Zahiri, H.; Stevens, C.; Spaanderman, D.; Milroy, L.-G.; Ottmann, C.; Brunsveld, L.; Voets, I.; Davies, P.
10.1101/2020.11.18.389114 — microbiology — Posted on 2020-11-18
1632 Modeling Side-Stream Enhanced Biological Phosphorus Removal (S2EBPR) System Using Agent-based Model with Adaptive Maintenance, Decay and TCA Metabolism
Li, G.; Tooker, N. B.; Wang, D.; Srinivasan, V.; Barnard, J. L.; Russel, A.; Takacs, I.; Bott, C.; Dobrowski, P.; Onnis-Hayden, A.; Gu, A. Z.
10.1101/2020.11.18.387589 — microbiology — Posted on 2020-11-18
1634 Heme is crucial for medium-dependent metronidazole resistance in clinical isolates of C. difficile
Boekhoud, I. M.; Sidorov, I.; Nooij, S.; Harmanus, C.; Bos-Sanders, I. M. J. G.; Viprey, V.; Spittal, B.; Clark, E.; Davies, K.; Freeman, J.; Kuijper, E. J.; Smits, W. K.; COMBACTE-CDI Consortium, ; European Study Group for Clostridioides difficile,
10.1101/2020.11.18.388959 — microbiology — Posted on 2020-11-18
1637 Unifying the global coding sequence space enables the study of genes with unknown function across biomes
Vanni, C.; Schechter, M. S.; Acinas, S.; Barberan, A.; Buttigieg, P. L.; Casamayor, E. O.; Delmont, T. O.; Duarte, C. M.; Eren, A. M.; Finn, R. D.; Kottmann, R.; Mitchell, A.; Sanchez, P.; Siren, K.; Steinegger, M.; Glöckner, F. O.; Fernandez-Guerra, A.
10.1101/2020.06.30.180448 — microbiology — Posted on 2020-11-18
1638 The expression of PDCD1 and CD274 in T cells and macrophages correlated positively with COVID-19 severity
Gao, Q.; Liu, S.; Ding, R.; Chen, H.; Dong, X.; Xie, J.; Li, Y.; Chen, L.; Liu, H.; Mu, F.
10.1101/2020.11.17.378992 — immunology — Posted on 2020-11-18
1643 Rational Design and Synthesis of Selective PRMT4 Inhibitors: a New Chemotype for Development of Cancer Therapeutics
Sutherland, M.; Li, A.; Kaghad, A.; Panagopoulos, D.; Li, F.; Szewczyk, M.; Smil, D.; Scholten, C.; Bouche, L.; Stellfeld, T.; Arrowsmith, C.; Barsyte, D.; Vedadi, M.; Hartung, I. V.; Steuber, H.; Britton, R.; Santhakumar, V.
10.1101/2020.11.17.387233 — pharmacology and toxicology — Posted on 2020-11-18
1644 Structural requirements for dihydrobenzoxazepinone anthelmintics: actions against medically important and model parasites - Trichuris muris, Brugia malayi and Heligmosomoides polygyrus
Partridge, F. A.; Bataille, C. J.; Forman, R.; Marriott, A. E.; Häberli, C.; Dinsdale, R. L.; O'Sullivan, J. D.; Willis, N.; Archer, J.; Steven, A.; Taylor, M. J.; Keiser, J.; Turner, J. D.; Else, K. J.; Russell, A. J.; Sattelle, D. B.
10.1101/2020.11.17.384933 — pharmacology and toxicology — Posted on 2020-11-18
1646 LFMD: detecting low-frequency mutations in high-depth genome sequencing data without molecular tags
Ye, R.; Zhuang, X.; Ruan, J.; Qi, Y.; An, Y.; Xu, J.; Mak, T.; Liu, X.; Zhang, X.; Yang, H.; Xu, X.; Baum, L.; Nie, C.; Sham, P. C.
10.1101/617381 — bioinformatics — Posted on 2020-11-18
1647 Shape and size complementarity induced formation of supramolecular protein assemblies with metal-oxo clusters
Vandebroek, L.; Noguchi, H.; Kamata, K.; Tame, J. R. H.; Van Meervelt, L.; Parac-Vogt, T. N.; Voet, A. R. D.
10.1101/2020.11.18.388215 — biochemistry — Posted on 2020-11-18
1649 A unique adhesive motif of protein disulfide isomerase P5 supports its function via dimerization
Okumura, M.; Kanemura, S.; Matsusaki, M.; Kinoshita, M.; Saio, T.; Ito, D.; Hirayama, C.; Kumeta, H.; Watabe, M.; Amagai, Y.; Lee, Y.-H.; Akiyama, S.; Inaba, K.
10.1101/2020.11.17.387910 — biochemistry — Posted on 2020-11-18
1651 Subtractive CRISPR screen identifies factors involved in non-canonical LC3 lipidation.
Ulferts, R.; Marcassa, E.; Timimi, L.; Lee, L. C.; Daley, A.; Montaner, B.; Turner, S. D.; Florey, O.; Baillie, J. K.; Beale, R.
10.1101/2020.11.18.388306 — cell biology — Posted on 2020-11-18
1653 An engineered receptor-binding domain improves the immunogenicity of multivalent SARS-CoV-2 vaccines
Quinlan, B. D.; Li, W.; Mou, H.; Zhang, L.; Chang, J.; Peng, S.; Ojha, A.; Tavora, R.; Parcells, M. S.; Luo, G. G.; Li, W.; Zhong, G.; Choe, H.; Farzan, M.
10.1101/2020.11.18.388934 — microbiology — Posted on 2020-11-18
1655 Human fecal microbiota is associated with colorectal cancer
Yao, Q.; Tang, M.; Zeng, L.; Chu, Z.; Sheng, H.; Zhang, Y.; Zhou, Y.; Zhang, H.; Jiang, H.; Ye, M.
10.1101/2020.11.17.387647 — microbiology — Posted on 2020-11-18
1656 The human cytomegalovirus protein UL116 interacts with the viral ER resident glycoprotein UL148 and promotes the incorporation of gH/gL complexes into virions
Siddiquey, M. N. A.; Schultz, E. P.; Yu, Q.; Amendola, D.; Vezzani, G.; yu, d.; Maione, D.; Lanchy, J.-M.; Ryckman, B. J.; Merola, M.; Kamil, J. P.
10.1101/2020.11.17.387944 — microbiology — Posted on 2020-11-18
1657 A wide-ranging Pseudomonas aeruginosa PeptideAtlas build: a useful proteomic resource for a versatile pathogen.
Reales-Calderon, J. A.; Sun, Z.; Mascaraque, V.; Perez-Navarro, E.; Vialas, V.; Deutsch, E. W.; Moritz, R. L.; Gil, C.; Martinez, J. L.; Molero, G.
10.1101/2020.11.18.386490 — microbiology — Posted on 2020-11-18
1659 The human cytomegalovirus UL116 glycoprotein is a chaperone to control gH-based complexes levels on virions
Vezzani, G.; Amendola, D.; Yu, D.; Chandramouli, S.; Frigimelica, E.; Maione, D.; Merola, M.
10.1101/2020.11.18.387126 — microbiology — Posted on 2020-11-18
1660 Production of anti-SARS-CoV-2 hyperimmune globulin from convalescent plasma
Vandeberg, P.; Cruz, M.; Diez, J. M.; Merritt, W. K.; Santos, B.; Trukawinski, S.; Wellhouse, A.; Jose, M.; Willis, T.
10.1101/2020.11.18.388991 — immunology — Posted on 2020-11-18
1663 Depth-discrete metagenomics reveals the roles of microbes in biogeochemical cycling in the tropical freshwater Lake Tanganyika
Tran, P. Q.; Bachand, S. C.; McIntyre, P. B.; Kraemer, B. M.; Vadeboncoeur, Y.; Kimirei, I. A.; Tamatamah, R.; McMahon, K. D.; Anantharaman, K.
10.1101/834861 — microbiology — Posted on 2020-11-18
1665 Enforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration
Vidal, R. L.; Sepulveda, D.; Troncoso-Escudero, P.; Garcia-Huerta, P.; Gonzalez, C.; Plate, L.; Jerez, C.; Canovas, J.; Rivera, C.; Castillo, V.; Cisternas, M.; Leal, S.; Martinez, A.; Grandjean, J.; Lashuel, H.; Martin, A. J. M.; Latapiat, V.; Matus, S.; Sardi, S. P.; Wiseman, L.; Hetz, C.
10.1101/2020.11.17.387480 — neuroscience — Posted on 2020-11-18
1671 Long-chain polyphosphates impair SARS-CoV-2 infection and replication: a route for therapy in man
Ferrucci, V.; Dae, Y. K.; Asadzadeh, F.; Marrone, L.; Siciliano, R.; Cerino, P.; Criscuolo, G.; Pisano, I.; Quarantelli, F.; Izzo, B.; Fusco, G.; Comegna, M.; Boccia, A.; Viscardi, M.; Borriello, G.; Brandi, S.; Pierri, B. M.; Tiberio, C.; Atripaldi, L.; Paolella, G.; Castaldo, G.; Pascarella, S.; Bianchi, M.; Della Monica, R.; Chiariotti, L.; Yun, K. S.; Cheong, J. H.; Kim, H. Y.; Zollo, M.
10.1101/2020.11.18.388413 — genetics — Posted on 2020-11-18
1673 An assessment of efficacy of Iodine complex (Renessans) against SARS-CoV-2 in non-human primates (Rhesus macaque)
Nawaz, M.; Ali, M. A.; Ashraf, M. A.; Shabbir, M. Z.; Shabbir, M. A. B.; Altaf, I.; Raza, S.; Rafique, S.; Hassan, S.; Sardar, N.; Mehmood, A.; Aziz, M. W.; Fazal, S.; Khan, M. T.; Atique, M. M.; Asif, A.; Ullah, Z.; Iqbal, M.; Imtiaz, T.; Anwar, M.; Mukhtar, N.; Yaqub, T.
10.1101/2020.11.17.377432 — microbiology — Posted on 2020-11-18
1676 Single-cell Transcriptome of Bronchoalveolar Lavage Fluid Reveals Dynamic Change of Macrophages During SARS-CoV-2 Infection in Ferrets
Lee, J. S.; Koh, J.-Y.; Yi, K.; Kim, Y.-I.; Park, S.-J.; Kim, E.-H.; Kim, S.-M.; Park, S. H.; Ju, Y. S.; Choi, Y. K.; Park, S.-H.
10.1101/2020.11.18.388280 — immunology — Posted on 2020-11-18
1677 High-dimensional association detection in large scale genomic data
Koch, H.; Keller, C. A.; Giardine, B.; Xiang, G.; Zhang, F.; Wang, Y.; Hardison, R. C.; Li, Q.
10.1101/2020.11.18.388504 — bioinformatics — Posted on 2020-11-18
1678 Improved production of SARS-CoV-2 spike receptor-binding domain (RBD) for serology assays
Mehalko, J.; Drew, M.; Snead, K.; Denson, J.-P.; Wall, V.; Taylor, T.; Sadtler, K.; Messing, S.; Gillette, W.; Esposito, D.
10.1101/2020.11.18.388868 — biochemistry — Posted on 2020-11-18
1679 Generation and Characterization of recombinant SARS-CoV-2 expressing reporter genes
Chiem, K.; Morales Vasquez, D.; Park, J.-G.; Platt, R. N.; Anderson, T.; Walter, M. R.; Kobie, J. J.; Ye, C.; Martinez-Sobrido, L.
10.1101/2020.11.16.386003 — microbiology — Posted on 2020-11-18
1680 Activation of the Integrated Stress Response in drug-tolerant melanoma cells confers vulnerability to mitoribosome-targeting antibiotics.
Vendramin, R.; Konnova, A.; Adnane, S.; Cinque, S.; Katopodi, V.; Knezevic, Z.; Karras, P.; Demesmaeker, E.; Bosisio, F. M.; Rizzotto, L.; Bechter, O.; Marine, J.-C.; Leucci, E.
10.1101/2020.06.26.173492 — cancer biology — Posted on 2020-11-18
1681 WEVar: a novel statistical learning framework for predicting noncoding regulatory variants
Chen, L.; Jiang, Y.; Yao, B.; Huang, K.; Liu, Y.; Wang, Y.; Qin, X.; Saykin, A. J.; Wang, Y.
10.1101/2020.11.16.385633 — bioinformatics — Posted on 2020-11-18
1684 Fascin1 empowers YAP mechanotransduction and promotes cholangiocarcinoma development
Pocaterra, A.; Ament, C.; Ribbak, S.; Evert, M.; Chen, X.; Calvisi, D.; Dupont, S.
10.1101/2020.11.18.388397 — cancer biology — Posted on 2020-11-18
1686 Biochemical and Biophysical Characterization of the dsDNA packaging motor from the Lactococcus lactis bacteriophage asccphi28
Reyes-Aldrete, E.; Dill, E.; Bussetta, C.; Szymanski, M. R.; Diemer, G. S.; Maindola, P.; White, M.; Choi, K.; Morais, M.
10.1101/2020.11.17.383745 — biophysics — Posted on 2020-11-18
1689 DUBStepR: correlation-based feature selection for clustering single-cell RNA sequencing data
Ranjan, B.; Sun, W.; Park, J.; Xie, R.; Alipour, F.; Mishra, K.; Singhal, V.; Prabhakar, S.
10.1101/2020.10.07.330563 — bioinformatics — Posted on 2020-11-18
1691 Human Pumilio proteins directly bind the CCR4-NOT deadenylase complex to regulate the transcriptome
Enwerem, I. I. I.; Elrod, N. D.; Chang, C.-T.; Lin, A.; Ji, P.; Bohn, J. A.; Levdansky, Y.; Wagner, E. J.; Valkov, E.; Goldstrohm, A.
10.1101/2020.11.17.387456 — molecular biology — Posted on 2020-11-18
1694 Neuraminidase inhibitors rewire neutrophil function in murine sepsis and COVID-19 patients' cells
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Barroso, S. P. C.; Morrot, A.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Maurici, R.; Bafica, A.; Macauley, M. S.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2020-11-18
1696 Freshwater monitoring by nanopore sequencing
Urban, L.; Holzer, A.; Baronas, J. J.; Hall, M.; Braeuninger-Weimer, P.; Scherm, M. J.; Kunz, D. J.; Perera, S. N.; Martin-Herranz, D. E.; Tipper, E. T.; Salter, S. J.; Stammnitz, M. R.
10.1101/2020.02.06.936302 — microbiology — Posted on 2020-11-18
1698 Multiplexed single-cell profiling of chromatin states at genomic loci by expansion microscopy
Woodworth, M. A.; Ng, K. K. H.; Halpern, A. R.; Pease, N. A.; Nguyen, P. H. B.; Kueh, H. Y.; Vaughan, J. C.
10.1101/2020.11.17.385476 — genomics — Posted on 2020-11-18
1702 Genome-wide analysis of long noncoding RNAs, 24-nt siRNAs, DNA methylation and H3K27me3 marks in Brassica rapa and related species
Mehraj, H.; Shea, D. J.; Takahashi, S.; Miyaji, N.; Akter, A.; Seki, M.; Dennis, E. S.; Fujimoto, R.; Osabe, K.
10.1101/2020.11.06.370940 — plant biology — Posted on 2020-11-18
1703 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-11-18
1705 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-18
1707 Elephant endotheliotropic herpesvirus is omnipresent in elephants in European zoos and an Asian elephant range country
Hoornweg, T. E.; Schaftenaar, W.; Maurer, G.; van den Doel, P. B.; Molenaar, F. M.; Chamouard-Galante, A.; Vercammen, F.; Rutten, V.; de Haan, C. A. M.
10.1101/2020.11.16.386011 — microbiology — Posted on 2020-11-18
1708 Streptococcus pneumoniae serotypes carried by young children and their association with Acute Otitis Media during the period 2016 - 2019.
Ekinci, E.; Desmet, S.; Van Heirstraeten, L.; Mertens, C.; Wouters, I.; Beutels, P.; Verhaegen, J.; Malhotra-Kumar, S.; Theeten, H.; Npcarriage Study Group, T.
10.1101/2020.11.16.386052 — immunology — Posted on 2020-11-18
1709 Degradation of mixed-linkage (1,3;1,4)-β-D-glucan in maize is mediated by the CAL1 licheninase
Kraemer, F. J.; Lunde, C.; Koch, M.; Kuhn, B. M.; Ruehl, C.; Brown, P.; Hoffmann, P.; Göhre, V.; Hake, S.; Pauly, M.; Ramirez, V.
10.1101/2020.11.16.385146 — plant biology — Posted on 2020-11-18
1714 Deciphering a marine bone degrading microbiome reveals a complex community effort
Borchert, E.; Garcia-Moyano, A.; Sanchez-Carrillo, S.; Dahlgren, T. G.; Slaby, B.; Bjerga, G. E. K.; Ferrer, M.; Franzenburg, S.; Hentschel, U.
10.1101/2020.05.13.093005 — microbiology — Posted on 2020-11-18
1716 GSAP regulates mitochondrial function through the Mitochondria-associated ER membrane in the pathogenesis of Alzheimer's disease
Xu, P.; Chang, J. C.; Zhou, X.; Wang, W.; Bamkole, M.; Wong, E.; Bettayeb, K.; Jiang, L.-L.; Huang, T.; Luo, W.; Xu, H.; Nairn, A. C.; Flajolet, M.; Ip, N.; Li, Y.-M.; Greengard, P.
10.1101/2020.11.17.385245 — neuroscience — Posted on 2020-11-18
1717 Unified neural pathways that gate affective pain and multisensory innate threat signals to the amygdala
Kang, S. J.; Liu, S.; Ye, M.; Kim, D.-I.; Kim, J.-H.; Oh, T. G.; Peng, J.; Evans, R. M.; Lee, K.-F.; Goulding, M.; Han, S.
10.1101/2020.11.17.385104 — neuroscience — Posted on 2020-11-18
1719 The proteomic landscape of resting and activated CD4+ T cells reveal insights into cell differentiation and function
Subbannayya, Y.; Haug, M.; Pinto, S.; Mohanty, V.; Meas, H. Z.; Flo, T. H.; Prasad, T. S. K.; Kandasamy, R. K.
10.1101/2020.11.17.385096 — immunology — Posted on 2020-11-18
1722 USP28 deletion and small molecule inhibition destabilises c-Myc and elicitsregression of squamous cell lung carcinoma
Ruiz, E. J.; Pinto-Fernandez, A.; Turnbull, A. P.; Lan, L.; Charlton, T. M.; Scott, H. C.; Damianou, A.; Vere, G.; Riising, E. M.; Da Costa, C.; Krajewski, W. W.; Guerin, D.; Kearns, J.; Ioannidis, S.; Katz, M.; O'Connell, J. C.; Moncaut, N.; Rosewell, I.; Nye, E.; Jones, N.; Heride, C.; Gersch, M.; Wu, M.; Dinsmore, C. J.; Hammonds, T. R.; Kim, S.; Komander, D.; Urbe, S.; Clague, M. J.; Kessler, B. M.; Behrens, A.
10.1101/2020.11.17.377705 — cancer biology — Posted on 2020-11-17
1726 Queuine is a nutritional regulator of Entamoeba histolytica response to oxidative stress and a virulence attenuator
Nagaraja, S.; Cai, M. W.; Sun, J.; Varet, H.; Sarid, L.; Shaulov, Y.; Trebicz-Geffen, M.; Mazumdar, M.; Legendre, R.; Coppee, J.-Y.; Begley, T.; Dedon, P. C.; Gourinath, S.; Guillen, N.; Saito-Nakano, Y.; Shimokawa, C.; Hisaeda, H.; Ankri, S.
10.1101/2020.04.30.070276 — microbiology — Posted on 2020-11-17
1727 Acute social isolation causes midbrain craving responses similar to hunger.
Tomova, L.; Wang, K.; Thompson, T.; Matthews, G.; Takahashi, A.; Tye, K.; Saxe, R.
10.1101/2020.03.25.006643 — neuroscience — Posted on 2020-11-17
1730 KDM2B promotes cell viability by enhancing DNA damage response in canine hemangiosarcoma
Gulay, K. C. M.; Aoshima, K.; Shibata, Y.; Yasui, H.; Yan, Q.; Kobayashi, A.; Kimura, T.
10.1101/2020.11.17.387704 — cancer biology — Posted on 2020-11-17
1731 Transient genomic instability drives tumorigenesis through accelerated clonal evolution
Shoshani, O.; Bakker, B.; Wang, Y.; Kim, D. H.; Maldonado, M.; Demarest, M. A.; Artates, J.; Zhengyu, O.; Mark, A.; Wardenaar, R.; Sasik, R.; Spierings, D. C.; Vitre, B.; Fisch, K.; Foijer, F.; Cleveland, D. W.
10.1101/2020.11.17.387753 — cancer biology — Posted on 2020-11-17
1736 MrvR, a group B Streptococcus transcription factor that controls multiple virulence traits
Dammann, A. N.; Chamby, A. B.; Catomeris, A. J.; Davidson, K. M.; Tettelin, H.; van Pijkeren, J. P.; Gopalakrishna, K. P.; Keith, M. F.; Elder, J. L.; Ratner, A. J.; Hooven, T.
10.1101/2020.11.17.386367 — microbiology — Posted on 2020-11-17
1739 LRP1 and SORL1 regulate tau internalization and degradation and enhance tau seeding
Cooper, J. M.; Lathuiliere, A.; Migliorini, M.; Arai, A. L.; Wani, M. M.; Dujardin, S.; Muratoglu, S. C.; Hyman, B. T.; Strickland, D.
10.1101/2020.11.17.386581 — neuroscience — Posted on 2020-11-17
1743 A plant lipocalin is required for retinal-mediated de novo root organogenesis
Dickinson, A. J.; Zhang, J.; Luciano, M.; Wachsman, G.; Schnermann, M.; Dinneny, J. R.; Benfey, P. N.
10.1101/2020.11.09.375444 — plant biology — Posted on 2020-11-17
1752 Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells
Pae, J.; Ersching, J.; Castro, T. B.; Schips, M.; Mesin, L.; Allon, S. J.; Ordovas-Montanes, J.; Mlynarczyk, C.; Melnick, A.; Efeyan, A.; Shalek, A. K.; Meyer-Hermann, M.; Victora, G. D.
10.1101/2020.11.17.385716 — immunology — Posted on 2020-11-17
1756 NAP-CNB: Bioinformatic pipeline to predict MHC-I-restricted T cell epitopes in mice
Wert-Carvajal, C.; Sanchez-Garcia, R.; Macias, J. R.; Sanz-Pamplona, R.; Mendez Perez, A.; Alemany, R.; Veiga, E.; Sorzano, C. O. S.; Munoz-Barrutia, A.
10.1101/2020.10.05.327015 — bioinformatics — Posted on 2020-11-17
1759 Knockout of myoc reveals the role of myocilin in zebrafish sex determination associated with Wnt signalling downregulation
Atienzar-Aroca, R.; Aroca-Aguilar, J.-D.; Alexandre-Moreno, S.; Ferre-Fernández, J.-J.; Juan-Manuel Bonet-Fernández, J.-M.; Cabañero-Varela, M.-J.; Escribano, J.
10.1101/2020.11.17.380147 — genetics — Posted on 2020-11-17
1764 PrimPol-dependent single-stranded gap formation mediates homologous recombination at bulky DNA adducts
Piberger, A. L.; Bowry, A.; Kelly, R. D. W.; Walker, A. K.; Gonzalez, D.; Bailey, L. J.; Doherty, A. J.; Mendez, J.; Morris, J. R.; Bryant, H. E.; Petermann, E.
10.1101/773242 — molecular biology — Posted on 2020-11-17
1767 Immunogenicity of one- and two-dose regimens of the Ad26.COV2.S COVID-19 vaccine candidate in adult and aged rhesus macaques
Solforosi, L.; Kuipers, H.; Rosendahl Huber, S. K.; van der Lubbe, J. E. M.; Dekking, L.; Czapska-Casey, D. N.; Izquierdo Gil, A.; Baert, M.; Drijver, J.; Vaneman, J.; van Huizen, E.; Choi, Y.; Vreugdenhil, J.; Dalebout, T. J.; Myeni, S. K.; Kikkert, M.; Snijder, E. J.; Barouch, D. H.; Koopman, G.; Mooij, P.; Bogers, W. M. J. M.; Muchene, L.; Tolboom, J. T. B. M.; Roozendaal, R.; Schuitemaker, H.; Wegmann, F.; Zahn, R. C.
10.1101/2020.11.17.368258 — immunology — Posted on 2020-11-17
1768 Rab27 GTPases regulate alpha-synuclein uptake, cell-to-cell 1 transmission, and toxicity
Underwood, R. N.; Wang, B.; Pathak, A.; Volpicelli-Daley, L.; Yacoubian, T. A.
10.1101/2020.11.17.387449 — neuroscience — Posted on 2020-11-17
1770 Palmitoylation Couples DLK to JNK3 to Facilitate Pro-degenerative Axon-to-Soma Signaling
Niu, J.; Holland, S. M.; Ketschek, A.; Collura, K. M.; Hayashi, T.; Smith, G. M.; Gallo, G.; Thomas, G.
10.1101/2020.11.17.387191 — neuroscience — Posted on 2020-11-17
1771 Mathematical modeling of ventilator-induced lung inflammation
Minucci, S. B.; Valentine, M. S.; Kamga Gninzeko, F. J.; Heise, R. L.; Reynolds, A. M.
10.1101/2020.06.03.132258 — systems biology — Posted on 2020-11-17
1772 SBGN Bricks Ontology as a tool to describe recurring concepts in molecular networks
Rougny, A.; Toure, V.; Albanese, J.; Waltemath, D.; Shirshov, D.; Sorokin, A.; Bader, G. D.; Blinov, M. L.; Mazein, A.
10.1101/2020.11.16.369330 — systems biology — Posted on 2020-11-17
1773 Acid sensing ion channel 1a is a key mediator of cardiac ischemia-reperfusion injury
Redd, M.; Scheuer, S.; Saez, N.; Chiu, H.; Gao, L.; Hicks, M.; Villanueva, J.; Cuellar-Partida, G.; Peart, J.; See Hoe, L.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Hudson, J. E.; Porrello, E.; Fraser, J.; Petrou, S.; Reichelt, M.; Thomas, W.; King, G.; MacDonald, P.; Palpant, N.
10.1101/869826 — physiology — Posted on 2020-11-17
1775 Human melanocyte development and melanoma dedifferentiation at single cell resolution
Belote, R. L.; Le, D.; Maynard, A.; Lang, U. E.; Sinclair, A.; Planells-Palop, V.; Baskin, L. S.; Tward, A. D.; Darmanis, S.; Judson-Torres, R. L.
10.1101/2020.05.25.115287 — cancer biology — Posted on 2020-11-17
1776 EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells
Zangrossi, M.; Chakravarty, P.; Romani, P.; Ratcliffe, C. D. H.; Hooper, S.; Dori, M.; Forcato, M.; Bicciato, S.; Dupont, S.; Sahai, E.; MONTAGNER, M.
10.1101/2020.11.10.376186 — cancer biology — Posted on 2020-11-17
1778 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-17
1779 Thiol-ene cross-linked alginate hydrogel encapsulation modulates the extracellular matrix of kidney organoids by reducing abnormal type 1a1 collagen deposition
Geuens, T.; Ruiter, F. A. A.; Schumacher, A.; Morgan, F. L. C.; Rademakers, T.; Wiersma, L. E.; van den Berg, C. W.; Rabelink, T. J.; Baker, M. B.; LaPointe, V. L. S.
10.1101/2020.11.17.386250 — bioengineering — Posted on 2020-11-17
1782 UniBind: maps of high-confidence direct TF-DNA interactions across nine species
Riudavets Puig, R.; Boddie, P.; Khan, A.; Castro-Mondragon, J. A.; Mathelier, A.
10.1101/2020.11.17.384578 — genomics — Posted on 2020-11-17
1784 Population structure and transmission of Mycobacterium bovis in Ethiopia
Almaw, G.; Mekonnen, G. A.; Mihret, A.; Aseffa, A.; Taye, H.; Conlan, A. J.; Gumi, B.; Zewude, A.; Aliy, A.; Tamiru, M.; Olani, A.; Lakew, M.; Sombo, M.; Gebre, S.; Diguimbaye, C.; Hilty, M.; Fane, A.; Muller, B.; Hewinson, R. G.; Ellis, R. J.; Nunez-Garcia, J.; Palkopoulou, E.; The ETHICOBOTS consortium, ; Abebe, T.; Ameni, G.; Parkhill, J.; Wood, J. L.; Berg, S.; van Tonder, A. J.
10.1101/2020.11.17.386748 — genomics — Posted on 2020-11-17
1786 Investigating the shared genetic architecture between multiple sclerosis and inflammatory bowel diseases
Yang, Y.; Musco, H.; Simpson-Yap, S.; Zhu, Z.; Wang, Y.; Lin, X.; Zhang, J.; Taylor, B.; Gratten, J.; Zhou, Y.
10.1101/2020.11.16.385914 — genetics — Posted on 2020-11-17
1787 Genetic sensitivity analysis: adjusting for genetic confounding in epidemiological associations
Pingault, J.-B.; Rijsdijk, F.; Schoeler, T.; Choi, S. W.; Selzam, S.; Krapohl, E.; O'Reilly, P. F.; Dudbridge, F.
10.1101/592352 — genetics — Posted on 2020-11-17
1788 Inferring Adaptive Introgression Using Hidden Markov Models
Svedberg, J.; Shchur, V.; Reinman, S.; Nielsen, R.; Corbett-Detig, R.
10.1101/2020.08.02.232934 — evolutionary biology — Posted on 2020-11-17
1792 Development of a mass-spectrometry based method for the identification of the in vivo whole blood and plasma ADP-ribosylomes
Luethi, S. C.; Howard, A.; Nowak, K.; Graage, R.; Bartolomei, G.; Neupert, C.; Sidler, X.; Leslie Pedrioli, D. M.; Hottiger, M. O.
10.1101/2020.11.17.384719 — molecular biology — Posted on 2020-11-17
1793 Endothelial exosome plays functional role during rickettsial infection
Liu, Y.; Zhou, C.; Su, Z.; Chang, Q.; Qiu, Y.; Bei, J.; Gaitas, A.; Xiao, J.; Drelich, A.; Khanipov, K.; Jin, Y.; Golovko, G.; Berelli Saito, T.; Gong, B.
10.1101/2020.11.16.385740 — microbiology — Posted on 2020-11-17
1794 The Development of a Novel Nanobody Therapeutic for SARS-CoV-2
Ye, G.; Gallant, J.; Massey, C.; Shi, K.; Tai, W.; Zheng, J.; Odle, A.; Vickers, M.; Shang, J.; Wan, Y.; Drelich, A.; Kempaiah, K.; Tat, V.; Perlman, S.; Du, L.; Tseng, C.-T.; Aihara, H.; LeBeau, A.; Li, F.
10.1101/2020.11.17.386532 — microbiology — Posted on 2020-11-17
1795 Microbiomes attached to fresh perennial ryegrass- are temporally resilient and adapt to changing ecological niches
Huws, S.; Edwards, J.; Lin, W.; Rubino, F.; Alston, M.; Swarbeck, D.; Caim, s.; Rees Stevens, P.; Pachebat, J.; Won, M.-Y.; Oyama, L.; Creevey, C.; KIngston-Smith, A.
10.1101/2020.11.17.386292 — microbiology — Posted on 2020-11-17
1796 A LAMP-based microfluidic chip for rapid detection of pathogen in Cryptococcal meningitis
Guan, M.; Sui, G.; Tian, Y. r.; Zhang, T.; Guo, J.; Lu, H.; Yao, Y.; Chen, X.; Zhang, X.
10.1101/2020.11.16.386045 — microbiology — Posted on 2020-11-17
1797 Revealing interspecies transmission barriers of avian influenza A viruses
Naguib, M. M.; Eriksson, P.; Jax, E.; Nilsson, J.; Sihlbom, C.; Lindskog, C.; Brojer, C.; Olsson, B.-M.; Wille, M.; Waldenstroem, J.; Larson, G.; Kraus, R. H. S.; Lundkvist, A.; Olsen, B.; Jarhult, J. D.; Ellstrom, P.
10.1101/2020.11.17.386755 — microbiology — Posted on 2020-11-17
1798 The Rhinolophus affinis bat ACE2 and multiple animal orthologs are functional receptors for bat coronavirus RaTG13 and SARS-CoV-2
Li, P.; Guo, R.; Liu, Y.; Zhang, Y.; Hu, J.; Ou, X.; Mi, D.; Zhang, L.; wang, x.; Wu, Z.; Wang, J.; Jin, Q.; Qian, Z.
10.1101/2020.11.16.385849 — microbiology — Posted on 2020-11-17
1799 Enzyme specific isotope effects of the Nap and Nar nitrate reductases
Asamoto, C. K.; Rempfert, K. R.; Luu, V. H.; Younkin, A. D.; Kopf, S. H.
10.1101/2020.11.17.386888 — microbiology — Posted on 2020-11-17
1800 Universal antimicrobial resistance detection from clinical bacterial isolates using proteomics
Blumenscheit, C.; Pfeifer, Y.; Werner, G.; John, C.; Andy, S.; Lasch, P.; Joerg, D.
10.1101/2020.11.17.386540 — microbiology — Posted on 2020-11-17
1801 Small-molecule antibiotic inhibitors of post-translational protein secretion
Economou, A.; Burchacka, E.; Angus, L.; Marchand, A.; Hamed, M. B.; De Geyter, J.; Loos, M. S.; Anne, J.; Klaassen, H.; Chaltin, P.; Karamanou, S.
10.1101/2020.11.17.387027 — microbiology — Posted on 2020-11-17
1802 An Integrated Workflow for Enhanced Taxonomic and Functional Coverage of the Mouse Faecal Metaproteome
Nalpas, N.; Hoyles, L.; Anselm, V.; Ganief, T.; Martinez-Gili, L.; Grau, C.; Droste-Borel, I.; Davidovic, L.; Altafaj, X.; Dumas, M.-E.; Macek, B.
10.1101/2020.11.17.386938 — microbiology — Posted on 2020-11-17
1803 Structure of the mycobacterial ESX-5 Type VII Secretion System hexameric pore complex
Beckham, K. S. H.; Ritter, C.; Chojnowski, G.; Mullapudi, E.; Rettel, M.; Savitski, M. M.; Mortensen, S. A.; Kosinski, J.; Wilmanns, M.
10.1101/2020.11.17.387225 — microbiology — Posted on 2020-11-17
1804 Single-colony sequencing reveals phylosymbiosis, co-phylogeny, and horizontal gene transfer between the cyanobacterium Microcystis and its microbiome
Perez-Carrascal, O. M.; Tromas, N.; Terrat, Y.; Moreno, E.; Giani, A.; Braga Marques, L. C.; Fortin, N.; Shapiro, B. J.
10.1101/2020.11.17.386995 — microbiology — Posted on 2020-11-17
1805 A continuously self-sterilizing form of copper capable of 99% SARS-CoV-2 deactivation in 30 seconds.
Zinn, A. A.; Izadjoo, M.; Kim, H.; Kehn-Hall, K.; Lehman, C.; Brody, R. L.; Roth, R. R.; Vega, A.; Nguyen, K. K.; Ngo, N. T.; Zinn, H. T.; Panny, L.; Flor, R.; Antonopoulos, N.; Stoltenberg, R. M.
10.1101/2020.11.16.384040 — immunology — Posted on 2020-11-17
1806 An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19
Rappazzo, C. G.; Tse, L. V.; Kaku, C. I.; Wrapp, D.; Sakharkar, M.; Huang, D.; Deveau, L. M.; Yockachonis, T. J.; Herbert, A. S.; Battles, M. B.; O'Brien, C. M.; Brown, M. E.; Geoghegan, J. C.; Belk, J.; Peng, L.; Yang, L.; Scobey, T. D.; Burton, D. R.; Nemazee, D.; Dye, J. M.; Voss, J. E.; Gunn, B. M.; McLellan, J. S.; Baric, R. S.; Gralinski, L. E.; Walker, L. M.
10.1101/2020.11.17.385500 — immunology — Posted on 2020-11-17
1807 The proteomic landscape of resting and activated CD4+ T cells reveal insights into cell differentiation and function
Subbannayya, Y.; Haug, M.; Pinto, S.; Mohanty, V.; Meas, H. Z.; Prasad, T. S. K.; Flo, T. H.; Kandasamy, R. K.
10.1101/2020.11.17.385096 — immunology — Posted on 2020-11-17
1808 Maturation and persistence of the anti-SARS-CoV-2 memory B cell response.
Sokal, A.; Chappert, P.; Roeser, A.; Barba-Spaeth, G.; Fourati, S.; Azzaoui, I.; Vandenberghe, A.; Fernandez, I.; Bouvier-Alias, M.; Crickx, E.; Beldi Ferchiou, A.; Hue, S.; Languille, L.; Baloul, S.; Noizat-Pirenne, F.; Luka, M.; Megret, J.; Menager, M.; Pawlotsky, J.-M.; Fillatreau, S.; Rey, F. A.; Weill, J.-C.; Reynaud, C.-A.; Mahevas, M.
10.1101/2020.11.17.385252 — immunology — Posted on 2020-11-17
1812 An expanding manifold characterizes adolescent reconfigurations of structural connectome organization
Park, B.-y.; Bethlehem, R. A. I.; Paquola, C.; Lariviere, S.; Cruces, R. R.; Vos de Wael, R.; Neuroscience in Psychiatry Network (NSPN) Consortium, ; Bullmore, E. T.; Bernhardt, B.
10.1101/2020.06.22.165621 — neuroscience — Posted on 2020-11-17
1815 Optimal Adaptive Electrode Selection to Maximize Simultaneously Recorded Neuron Yield
Choi, J.; Kumar, K.; Khazali, M.; Wingel, K.; Choudhury, M.; Charles, A.; Pesaran, B.
10.1101/2020.10.06.328526 — neuroscience — Posted on 2020-11-17
1817 Immunoproteasome impairment via β5i/LMP7-deletion leads to sustained pancreatic injury and delayed recovery from experimental pancreatitis.
de Freitas Chama, L. L.; Ebstein, F.; Wiesrecker, B.; Wagh, P. R.; Weiss, F. U.; Lerch, M. M.; Krueger, E.; Sendler, M.
10.1101/2020.11.17.386482 — physiology — Posted on 2020-11-17
1820 Genome Diversity in Ukraine
Oleksyk, T. K.; Wolfsberger, W. W.; Weber, A.; Shchubelka, K.; Oleksyk, O. T.; Levchuk, O.; Patrus, A.; Lazar, N.; Castro-Marquez, S. O.; Boldyzhar, P.; Urbanovych, A.; Stakhovska, V.; Malyar, K.; Chervyakova, S.; Podoroha, O.; Kovalchuk, N.; Neymet, M.; Hasynets, Y.; Rodriguez-Flores, J. L.; Medley, S.; Battistuzzi, F. U.; Liu, R.; Hou, Y.; Chen, S.; Yang, H.; Yeager, M.; Dean, M.; Mills, R. E.; Smolanka, V.
10.1101/2020.08.07.238329 — genomics — Posted on 2020-11-17
1824 Evidence for natural hybridisation and novel Wolbachia strain superinfections in the Anopheles gambiae complex from Guinea
Jeffries, C. L.; Cansado Utrilla, C.; Beavogui, A. H.; Stica, C.; Lama, E. K.; Kristan, M.; Irish, S. R.; Walker, T.
10.1101/772855 — ecology — Posted on 2020-11-17
1827 Preclinical evaluation of Imatinib does not support its use as an antiviral drug against SARS-CoV-2
Touret, F.; Driouich, J.-S.; Cochin, M.; Petit, P. R.; Gilles, M.; Barthelemy, K.; Moureau, G.; Malvy, D.; Solas, C.; de Lamballerie, X.; Nougairede, A.
10.1101/2020.11.17.386904 — microbiology — Posted on 2020-11-17
1828 Transmission of SARS-CoV-2 in domestic cats imposes a narrow bottleneck
Braun, K. M.; Moreno, G. K.; Halfmann, P. J.; Baker, D. A.; Boehm, E. C.; Weiler, A. M.; Haj, A. K.; Hatta, M.; Chiba, S.; Maemura, T.; Kawaoka, Y.; Koelle, K.; O'Connor, D.; Friedrich, T.
10.1101/2020.11.16.384917 — microbiology — Posted on 2020-11-17
1829 Mosaic RBD nanoparticles elicit neutralizing antibodies against SARS-CoV-2 and zoonotic coronaviruses
Bjorkman, P. J.; Cohen, A. A.; Gnanapragasam, P. N. P.; Lee, Y. E.; Ou, S.; Kakutani, L. M.; Keeffe, J. R.; Barnes, C. O.; Nussenzweig, M. C.
10.1101/2020.11.17.387092 — immunology — Posted on 2020-11-17
1830 Reinforcing neuron extraction and spike inference in calcium imaging using deep self-supervised learning
Li, X.; Zhang, G.; Wu, J.; Zhang, Y.; Zhao, Z.; Lin, X.; Qiao, H.; Xie, H.; Wang, H.; Fang, L.; Dai, Q.
10.1101/2020.11.16.383984 — neuroscience — Posted on 2020-11-17
1832 Photostimulation of lymphatic clearance of red blood cells from the mouse brain after intraventricular hemorrhage
Li, D.; Liu, S.; Yu, T.; Liu, Z.; Sun, S.; Bragin, D.; Navolokin, N.; Kurths, J.; Semyachkina-Glushkovskaya, O. V.; Zhu, D.
10.1101/2020.11.16.384149 — neuroscience — Posted on 2020-11-17
1836 Perphenazine-macrocycle conjugates divert Aβ42 towards non-toxic aggregates by monomer sequestration.
Ball, S. R.; Adamson, J. S.; Sullivan, M. A.; Zimmermann, M. R.; Lo, V.; Sanz-Hernandez, M.; Jiang, F.; Kwan, A. H.; Werry, E. L.; Knowles, T. P.; Kassiou, M.; Meisl, G.; Todd, M. H.; Rutledge, P. R.; Sunde, M.
10.1101/2020.11.16.384248 — biophysics — Posted on 2020-11-17
1837 Amplification, not spreading limits rate of tau aggregate accumulation in Alzheimer's disease
Meisl, G.; Zuo, Y.; Allinson, K.; Rittman, T.; DeVos, S.; Sanchez, J. S.; Xu, C. K.; Duff, K. E.; Johnson, K. A.; Rowe, J.; Hyman, B.; Knowles, T. P.; Klenerman, D.
10.1101/2020.11.16.384727 — biophysics — Posted on 2020-11-17
1839 Comprehensive generation, visualization, and reporting of quality control metrics for single-cell RNA sequencing data
Hong, R.; Koga, Y.; Bandyadka, S.; Leshchyk, A.; Wang, Z.; Alabdullatif, S.; Wang, Y.; Akavoor, V.; Cao, X.; Sarfraz, I.; Jansen, F.; Johnson, W. E.; Yajima, M.; Campbell, J. D.
10.1101/2020.11.16.385328 — bioinformatics — Posted on 2020-11-17
1841 Low Repeatability of Aversive Learning in Zebrafish (Danio rerio)
Mason, D.; Zajitschek, S.; Anwer, H.; O'Dea, R.; Hesselson, D.; Nakagawa, S.
10.1101/2020.11.16.385930 — animal behavior and cognition — Posted on 2020-11-17
1842 Methylation Quantitative Trait Loci are Largely Consistent across Disease States in Crohns disease
Venkateswaran, S.; Somineni, H. K.; Kilaru, V.; Kartrinli, S.; Prince, J.; Okou, D.; Hyams, J. S.; Lee, D. A.; Kellermayer, R.; Gibson, G.; Cutler, D.; Smith, A. K.; Kugathasan, S.; Conneely, K.
10.1101/2020.11.16.385534 — genomics — Posted on 2020-11-17
1847 Microbial function is related to behavior of an invasive anuran
Zhou, J.; Nelson, T. M.; Rodriguez Lopez, C.; Zhou, S. J.; Ward-Fear, G.; Stuart, K. C.; Rollins, L. A.
10.1101/2020.11.16.385690 — microbiology — Posted on 2020-11-17
1848 Longitudinal characterization of phenotypic profile of T cells in chronic hepatitis B identifies immune markers predicting HBsAg loss
Xiong, S.; Zhu, D.; Liang, B.; Li, M.; Pan, W.; He, J.; Wang, H.; Kathrin, S.; Ulf, D.; Lu, M.; Liu, D.; Yang, D.; Liu, J.; Zheng, X.
10.1101/2020.11.16.382838 — microbiology — Posted on 2020-11-17
1850 Remote Digital Psychiatry: MindLogger for Mobile Mental Health Assessment and Therapy
Klein, A.; Clucas, J.; Krishnakumar, A.; Ghosh, S. S.; Van Auken, W.; Thonet, B.; Sabram, I.; Acuna, N.; Keshavan, A.; Rossiter, H.; Xiao, Y.; Semenuta, S.; Badioli, A.; Konishcheva, K.; Abraham, S. A.; Alexander, L. M.; Merikangas, K. R.; Swendsen, J.; Lindner, A. B.; Milham, M. P.
10.1101/2020.11.16.385880 — neuroscience — Posted on 2020-11-17
1853 Simplified and unified access to cancer proteogenomic data
Lindgren, C. M.; Adams, D. W.; Kimball, B.; Boekweg, H.; Tayler, S.; Pugh, S. L.; Payne, S. H.
10.1101/2020.11.16.385427 — bioinformatics — Posted on 2020-11-17
1856 Engineering self-organized criticality in living cells
Vidiella Rocamora, B.; Guillamon, A.; Sardanyes, J.; Maull, V.; Pueyo, N. C.; Sole, R.
10.1101/2020.11.16.385385 — bioengineering — Posted on 2020-11-17
1859 Draft Genome Assemblies and Annotations of Agrypnia vestita Walker, and Hesperophylaxmagnus Banks Reveal Substantial Repetitive Element Expansion in Tube Case-making Caddisflies (Insecta: Trichoptera)
Olsen, L. K.; Heckenhauer, J.; Sproul, J. S.; Dikow, R. B.; Gonzalez, V. L.; Kweskin, M. P.; Taylor, A. M.; Wilson, S. B.; Stewart, R. J.; Zhou, X.; Holzenthal, R.; Pauls, S. U.; Frandsen, P. B.
10.1101/2020.11.16.381806 — genomics — Posted on 2020-11-17
1861 Castration delays epigenetic aging and feminises DNA methylation at androgen-regulated loci
Sugrue, V. J.; Zoller, J. A.; Narayan, P.; Lu, A. T.; Ortega-Recalde, O. J.; Grant, M. J.; Bawden, C. S.; Rudiger, S. R.; Haghani, A.; Bond, D. M.; Garratt, M.; Sears, K. E.; Wang, N.; Yang, X.; Snell, R. G.; Hore, T. A.; Horvath, S.
10.1101/2020.11.16.385369 — developmental biology — Posted on 2020-11-17
1870 Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutations
Ursu, O.; Neal, J. T.; Shea, E.; Thakore, P. I.; Jerby-Arnon, L.; Nguyen, L.; Dionne, D.; Diaz, C.; Bauman, J.; Mosaad, M.; Fagre, C.; Giacomelli, A.; Ly, S. H.; Rozenblatt-Rosen, O.; Hahn, W.; Aguirre, A.; Berger, A.; Regev, A.; Boehm, J. S.
10.1101/2020.11.16.383307 — genomics — Posted on 2020-11-17
1871 K-seq, an affordable, reliable, and open Klenow NGS-based genotyping technology
Ziarsolo, P.; Hasing, T.; Hilario, R.; Garcia-Carpintero, V.; Blanca, J. M.; Bombarely, A.; Canizares, J.
10.1101/2020.11.16.360446 — genetics — Posted on 2020-11-17
1872 Temperature heterogeneity correlates with intraspecific variation in physiological flexibility in a small endotherm
Stager, M.; Senner, N. R.; Swanson, D. L.; Carling, M. D.; Eddy, D. K.; Grieves, T. J.; Cheviron, Z. A.
10.1101/2020.11.16.383877 — evolutionary biology — Posted on 2020-11-17
1875 Bacteria in biogas digestates for reduced climate forcing
Jonassen, K. R.; Hagen, L. H.; Vick, S.; Arntzen, M.; Eijsink, V. G. H.; Frostegard, A.; Lycus, P.; Molstad, L.; Bakken, L. R.
10.1101/2020.11.16.384990 — microbiology — Posted on 2020-11-17
1876 Identification of Covalent Modifications Regulating Immune Signaling Complex Composition and Phenotype
Frauenstein, A.; Ebner, S.; Sinha, A.; Kshiti, P.; Swatek, K.; Hornburg, D.; Mann, M.; Meissner, F.
10.1101/2020.11.16.384750 — systems biology — Posted on 2020-11-17
1877 Plant PhysioSpace: a robust tool to compare stress response across plant species
Hadizadeh Esfahani, A.; Mass, J.; Hallab, A.; Schuldt, B. M.; Usadel, B.; Ott, M.-C.; Buer, B.; Schuppert, A.
10.1101/2020.11.16.384305 — plant biology — Posted on 2020-11-17
1879 Inhibition of Fis1 by Novel Peptide Pep213 or Molecular Suppression Reverses Diabetic- and High Glucose-Induced Endothelial Dysfunction in Human Resistance Arteries
Karkala, M.; Egner, J.; Wang, J.; Harwig, M. C.; Meacham, K.; Puppala, V. K.; Hofeld, B. C.; Arnold, L. A.; Hill, R. B.; Widlansky, M. E.
10.1101/2020.11.16.385054 — physiology — Posted on 2020-11-17
1882 MegaGO: a fast yet powerful approach to assess functional similarity across meta-omics data sets
Verschaffelt, P.; Van Den Bossche, T.; Gabriel, W.; Burdukiewicz, M.; Soggiu, A.; Martens, L.; Renard, B. Y.; Schiebenhoefer, H.; Mesuere, B.
10.1101/2020.11.16.384834 — bioinformatics — Posted on 2020-11-17
1885 Comparative analysis of antibody- and lipid-based multiplexing methods for single-cell RNA-seq
Mylka, V.; Aerts, J.; Matetovici, I.; Poovathingal, S.; Vandamme, N.; Seurinck, R.; Hulselmans, G.; Van den Hoecke, S.; Wils, H.; Reumers, J.; Van Houdt, J.; Aerts, S.; Saeys, Y.
10.1101/2020.11.16.384222 — genomics — Posted on 2020-11-17
1886 Holocene plant diversity revealed by ancient DNA from 10 lakes in northern Fennoscandia
Rijal, D. P.; Heintzman, P. D.; Lammers, Y.; Yoccoz, N. G.; Lorberau, K. E.; Pitelkova, I.; Goslar, T.; Murguzur, F. J. A.; Salonen, J. S.; Helmens, K. F.; Bakke, J.; Edwards, M. E.; Alm, T.; Brathen, K. A.; Brown, A. G.; Alsos, I. G.
10.1101/2020.11.16.384065 — ecology — Posted on 2020-11-17
1893 Bifocal tACS Enhances Visual Motion Discrimination by Modulating Phase Amplitude Coupling Between V1 and V5 Regions
Salamanca, R.; Raffin, E.; Zandvliet, S.; Seeber, M.; Michel, C.; Sauseng, P.; Huxlin, K. R.; Hummel, F.
10.1101/2020.11.16.382267 — neuroscience — Posted on 2020-11-17
1895 Genomic landscapes of canine splenic angiosarcoma (hemangiosarcoma) contain extensive heterogeneity within and between patients
Wong, S.; Ehrhart, E.; Stewart, S.; Zismann, V.; Cawley, J.; Halperin, R.; Briones, N.; Richter, K.; Sivaprakasam, K.; Perdigones, N.; Contente-Cuomo, T.; Facista, S.; Trent, J. M.; Murtaza, M.; Khanna, C.; Hendricks, W. P. D.
10.1101/2020.11.15.380048 — cancer biology — Posted on 2020-11-17
1897 Multiscale PHATE Exploration of SARS-CoV-2 Data Reveals Multimodal Signatures of Disease
Kuchroo, M.; Huang, J.; Wong, P.; Grenier, J.-C.; Shung, D.; Tong, A.; Lucas, C.; Klein, J.; Burkhardt, D.; Gigante, S.; Godavarthi, A.; Israelow, B.; Mao, T.; Oh, J. E.; Silva, J.; Takahashi, T.; Odio, C. D.; Casanovas-Massana, A.; Fournier, J.; IMPACT Team, Y.; Farhadian, S.; Dela Cruz, C. S.; Ko, A. I.; Wilson, F. P.; Hussin, J.; Wolf, G.; Iwasaki, A.; Krishnaswamy, S.
10.1101/2020.11.15.383661 — bioinformatics — Posted on 2020-11-17
1901 Hydrogel-coating improves the in-vivo stability of electrochemical aptamer-based biosensors
Li, S.; Dai, J.; Zhu, M.; Arroyo-Curras, N.; Li, H.; Wang, Y.; Wang, Q.; Lou, X.; Kippin, T. E.; Wang, S.; Plaxco, K. W.; Li, H.; Xia, F.
10.1101/2020.11.15.383992 — bioengineering — Posted on 2020-11-17
1902 Novel quaternary structures of the human prion protein globular domain
Oliveira Bortot, L.; Lopes Rangel, V.; A. Pavlovici, F.; El Omari, K.; Wagner, A.; Brandao-Neto, J.; Talon, R.; von Delft, F.; G Reidenbach, A.; M Vallabh, S.; Vallabh Minikel, E.; Schreiber, S.; Cristina Nonato, M.
10.1101/2020.11.16.385856 — biochemistry — Posted on 2020-11-17
1905 Comprehensive mapping of tissue cell architecture via integrated single cell and spatial transcriptomics
Kleshchevnikov, V.; Shmatko, A.; Dann, E.; Aivazidis, A.; King, H. W.; Li, T.; Lomakin, A.; Kedlian, V.; Jain, M. S.; Park, J. S.; Ramona, L.; Tuck, E.; Arutyunyan, A.; Vento-Tormo, R.; Gerstung, M.; James, L.; Stegle, O.; Bayraktar, O. A.
10.1101/2020.11.15.378125 — genomics — Posted on 2020-11-17
1906 The landscape of autosomal-recessive pathogenic variants in European populations reveals phenotype-specific effects
Fridman, H.; Yntema, H. G.; Magi, R.; Andreson, R.; Metspalu, A.; Mezzavila, M.; Tyler-Smith, C.; Xue, Y.; Carmi, S.; Levy-Lahad, E.; Gilissen, C.; Brunner, H.
10.1101/2020.11.16.384206 — genetics — Posted on 2020-11-17
1907 Genomic and anatomical comparisons of skin support independent adaptation to life in water by cetaceans and hippos
Springer, M. S.; Guerrero-Juarez, C.; Huelsmann, M.; Collin, M. A.; Danil, K.; McGowen, M. R.; Oh, J. W.; Ramos, R.; Hiller, M.; Plikus, M. V.; Gatesy, J.
10.1101/2020.11.15.383638 — evolutionary biology — Posted on 2020-11-17
1908 A single origin of animal excretory organs
Gasiorowski, L.; Andrikou, C.; Bump, P.; Janssen, R.; Budd, G. E.; Lowe, C. J.; Hejnol, A.
10.1101/2020.11.15.378034 — evolutionary biology — Posted on 2020-11-17
1909 Multidimensionality in the thermal niches of dung beetles could limit species' responses to temperature changes
Calatayud, J.; Hortal, J.; Noriega, J. A.; Arcones, A.; Espinoza, V.; Guil, N.; Lobo, J. M.
10.1101/2020.11.15.383612 — ecology — Posted on 2020-11-17
1910 Predicting potential impacts of ocean acidification on marine calcifiersfrom the Southern Ocean
Figuerola, B.; Hancock, A. M.; Bax, N.; Cummings, V.; Downey, R.; Griffiths, H. J.; Smith, J.; Stark, J. S.
10.1101/2020.11.15.384131 — ecology — Posted on 2020-11-17
1911 Modelling species presence-only data with random forests
Valavi, R.; Elith, J.; Lahoz-Monfort, J. J.; Guillera-Arroita, G.
10.1101/2020.11.16.384164 — ecology — Posted on 2020-11-17
1912 Chondrocytes in the resting zone of the growth plate are maintained in a Wnt-inhibitory environment
Hallett, S. A.; Ono, W.; Matsushita, Y.; Sakagami, N.; Mizuhashi, K.; Tokavanich, N.; Nagata, M.; Zhou, A.; Hirai, T.; Kronenberg, H. M.; Ono, N.
10.1101/2020.11.15.383331 — developmental biology — Posted on 2020-11-17
1913 The nature of mitotic forces in epithelial monolayers
Gupta, V. K.; Nam, S.; Camuglia, J.; Martin, J. L.; Sanders, E. N.; O'Brien, L. E.; Martin, A. C.; Kim, T.; Chaudhuri, O.
10.1101/2020.11.16.378927 — cell biology — Posted on 2020-11-17
1914 Computer Designed PRC2 Inhibitor, EBdCas9, Reveals Functional TATA boxes in Distal Promoter Regions
Levy, S.; Somasundaram, L.; Xavier Raj, I.; Ic-Mex, D.; Schmidt, S.; Alghadeer, A.; Honkanen, H.; Hawkins, D. D.; Mathieu, J.; Wang, Y.; Baker, D.; Bomsztyk, K.; Ruohola-Baker, H.
10.1101/2020.11.16.385922 — molecular biology — Posted on 2020-11-17
1916 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-17
1917 Proteomic analysis reveals Utf1 as a neurogenesis-associated new Sumo target
Correa-Vazquez, J. F.; Juarez-Vicente, F.; Garcia-Gutierrez, P.; Barysch, S. V.; Melchior, F.; Garcia-Dominguez, M.
10.1101/2020.11.17.386557 — cell biology — Posted on 2020-11-17
1918 HIV-1 provirus excised by single CRISPR/Cas9 RNA guide persists in host cell and may be reactivated
Lai, M.; Maori, E.; Quaranta, P.; Matteoli, G.; Maggi, F.; Sgarbanti, M.; Crucitta, S.; Paci, S.; Turriziani, O.; Freer, G.; Heeney, J. L.; Antonelli, G.; Pistello, M.
10.1101/2020.11.16.384180 — microbiology — Posted on 2020-11-17
1923 Quaternary climate change explains global patterns of tree beta-diversity
Xu, W.-B.; Guo, W.-Y.; Serra-Diaz, J. M.; Schrodt, F.; Eiserhardt, W. L.; Enquist, B. J.; Maitner, B. S.; Merow, C.; Violle, C.; Anand, M.; Belluau, M.; Bruun, H. H.; Byun, C.; Catford, J. A.; Cerabolini, B. E. L.; Chacon-Madrigal, E.; Ciccarelli, D.; Cornelissen, J. H. C.; Dang-Le, A. T.; de Frutos, A.; Dias, A. S.; Giroldo, A. B.; Gutierrez, A. G.; Hattingh, W.; He, T.; Hietz, P.; Hough-Snee, N.; Jansen, S.; Kattge, J.; Komac, B.; Kraft, N.; Kramer, K.; Lavorel, S.; Lusk, C. H.; Martin, A. R.; Ma, K.-P.; Mencuccini, M.; Michaletz, S. T.; Minden, V.; Mori, A. S.; Niinemets, U.; Onoda, Y.; Ons
10.1101/2020.11.14.382846 — ecology — Posted on 2020-11-17
1924 Lysyl oxidase-like 2 (LOXL2) is Increased in Asthma and Contributes to Asthmatic Airway Remodelling
Ramis, J.; Middlewick, R.; Pappalardo, F.; Cairns, J. T.; Stewart, I. D.; John, A. E.; Naveed, S.-u.; Krishnan, R.; Miller, S.; Shaw, D. E.; Brightling, C. E.; Buttery, L.; Rose, F. R.; Jenkins, G.; Johnson, S. R.; Tatler, A. L.
10.1101/2020.11.16.384792 — cell biology — Posted on 2020-11-17
1927 A Streptomyces venezuelae Cell-Free Toolkit for Synthetic Biology
Moore, S.; Lai, H.-E.; Chee, S.-M.; Toh, M.; Coode, S.; Capel, P.; Corre, C.; de los Santos, E.; Freemont, P.
10.1101/2020.11.16.384693 — synthetic biology — Posted on 2020-11-17
1930 Methyltransferase SMYD5 Exaggerates IBD by Downregulating Mitochondrial Functions via Post-translational Control of PGC-1α Stability
Hou, Y.; Sun, X.; Gheinani, P. T.; Guan, X.; Sharma, S.; Zhou, Y.; Jin, C.; Yang, Z.; Naren, A. P.; Yin, J.; Denning, T. L.; Gewirtz, A. T.; Xie, Z.; Li, C.
10.1101/2020.11.16.385765 — cell biology — Posted on 2020-11-17
1934 A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL
Rice, S.; Jackson, T.; Crump, N. T.; Fordham, N.; Elliott, N.; O Byrne, S.; Inglott, S.; Ladon, D.; Wright, G.; Bartram, J.; Ancliff, P.; Mead, A. J.; Halsey, C.; Roberts, I.; Milne, T. A.; Roy, A.
10.1101/2020.11.15.379990 — cancer biology — Posted on 2020-11-17
1936 Revisiting the notion of deleterious sweeps
Johri, P.; Charlesworth, B.; Howell, E. K.; Lynch, M.; Jensen, J. D.
10.1101/2020.11.16.385666 — evolutionary biology — Posted on 2020-11-17
1937 Threat-induced hippocampal connectivity fingerprints do not generalize to psychosocial stress
Kuehnel, A.; Czisch, M.; Saemann, P. G.; BeCome working group, ; Binder, E. B.; Kroemer, N. B.
10.1101/2020.11.16.380220 — neuroscience — Posted on 2020-11-17
1939 Distinct and Common Neural Coding of Semantic and Non-semantic Control Demands
Gao, Z.; Zheng, L.; Chiou, R.; Gouws, A.; Krieger-Redwood, K.; Wang, X.; Varga, D.; Lambon Ralph, M.; Smallwood, J.; Jefferies, E.
10.1101/2020.11.16.384883 — neuroscience — Posted on 2020-11-17
1941 HOX13-MEDIATED DBX2 REGULATION IN LIMBS SUGGESTS INTER-TAD SHARING OF ENHANCERS
Beccari, L.; Jaquier, G.; Lopez-Delisle, L.; Rodriguez-Carballo, E.; Mascrez, B.; Gitto, S.; Woltering, J.; Duboule, D.
10.1101/2020.11.16.379412 — developmental biology — Posted on 2020-11-17
1945 Metabolic potential, ecology and presence of endohyphal bacteria is reflected in genomic diversity of Mucoromycotina
Muszewska, A.; Okrasinska, A.; Steczkiewicz, K.; Drgas, O.; Orłowska, M.; Perlinska-Lenart, U.; Aleksandrzak-Piekarczyk, T.; Szatraj, K.; Zielenkiewicz, U.; Piłsyk, S.; Malc, E.; Mieczkowski, P.; Kruszewska, J. S.; Bernat, P.; Pawłowska, J.
10.1101/2020.11.16.384453 — genomics — Posted on 2020-11-16
1947 Evaluation of saliva as a source of accurate whole-genome and microbiome sequencing data
Herzig, A.; Velo-Suarez, L.; Le Folgoc, G.; Boland, A.; Blanche, H.; Olaso, R.; Le Roux, L.; Delmas, C.; Goldberg, M.; Zins, M.; Lethimonnier, F.; Deleuze, J.-F.; Genin, E.
10.1101/2020.11.16.384438 — genetics — Posted on 2020-11-16
1949 Phylodynamic analysis of an emergent Mycobacterium bovis outbreak in an area with no previously known wildlife infections
Rossi, G.; Crispell, J.; Brough, T.; Lycett, S. J.; White, P. C. L.; Allen, A.; Ellis, R. J.; Gordon, S. V.; Harwood, R.; Palkopoulou, E.; Presho, E.; Skuce, R.; Smith, G. C.; Kao, R. R.
10.1101/2020.11.12.379297 — ecology — Posted on 2020-11-16
1950 Seizing diminishing habitat conservation and restoration opportunities in the Tampa Bay, FL watershed: An urban estuary in recovery
Raulerson, G. E.; Robison, D. E.; Beck, M. W.; Burke, M. C.; Ries, T. F.; Saarinen, J. A.; Sciarrino, C. M.; Sherwood, E. T.; Tomasko, D. A.
10.1101/2020.11.16.384404 — ecology — Posted on 2020-11-16
1957 Color compensation in anomalous trichromats assessed with fMRI
Tregillus, K. E. M.; Isherwood, Z. J.; Vanston, J. E.; Engel, S. A.; MacLeod, D. I. A.; Kuriki, I.; Webster, M. A.
10.1101/2020.08.18.256701 — neuroscience — Posted on 2020-11-16
1958 Multiomics data collection, visualization, and utilization for guiding metabolic engineering
Roy, S.; Radivojevic, T.; Forrer, M.; Marti, J. M.; Jonnalagadda, V.; Backman, T.; Morrell, W.; Plahar, H.; Kim, J.; Hillson, N.; Martin, H. G.
10.1101/2020.10.15.341909 — synthetic biology — Posted on 2020-11-16
1959 Comprehensive studies of Head Maralla, Punjab, Pakistan vegetation for ethnopharmacological and ethnobotanical uses and their elaboration through quantitative indices
Iqbal, M. S.; Ali, M. A.; Akbar, M.; Hussain, S. A.; Arshad, N.; Masood, H.; Munir, S.; Zafar, S.; Ahmad, T.; Shaheen, N.; Mashooq, R.; Sajjad, H.; Zahoor, M.; Bashir, F.; Shahbaz, K.; Arshad, H.; Fatima, N.; Nasir, F.; Hashmi, A. J.; Chaudhary, S.; Waqas, A.; Islam, M.
10.1101/2020.11.16.384420 — plant biology — Posted on 2020-11-16
1961 An Arf/Rab cascade controls the growth and invasiveness of glioblastoma
Kulasekaran, G.; Chaineau, M.; Piscapo, V. E.; Verginelli, F.; Fotouhi, M.; Girard, M.; Tang, Y.; Dali, R.; Lo, R.; Stifani, S.; McPherson, P. S.
10.1101/2020.04.30.070334 — cancer biology — Posted on 2020-11-16
1962 Streamlining Data-Intensive Biology With Workflow Systems
Reiter, T.; Brooks, P. T.; Irber, L.; Joslin, S. E. K.; Reid, C. M.; Scott, C.; Brown, C. T.; Pierce, N. T.
10.1101/2020.06.30.178673 — bioinformatics — Posted on 2020-11-16
1964 Predicting clinical drug response from model systems by non-linear subspace-based transfer learning
Mourragui, S.; Loog, M.; Vis, D. J.; Moore, K.; Manjon, A. G.; van de Wiel, M. A.; Reinders, M. J. T.; Wessels, L. F. A.
10.1101/2020.06.29.177139 — bioinformatics — Posted on 2020-11-16
1965 HGNChelper: Identification and correction of invalid gene symbols for human and mouse
Oh, S.; Abdelnabi, J.; Al-Dulaimi, R.; Aggarwal, A.; Ramos, M.; Davis, S. R.; Riester, M.; Waldron, L. D.
10.1101/2020.09.16.300632 — bioinformatics — Posted on 2020-11-16
1968 DNA Replication Stress Generates Distinctive Landscapes of DNA Copy Number Alterations and Chromosome Scale Losses
Shaikh, N.; Mazzagatti, A.; Bakker, B.; Spierings, D. C. J. E.; Wardenaar, R.; Maniati, E.; Larsson, P.; Wang, J.; Boemo, M. A.; Foijer, F.; McClelland, S. E.
10.1101/743658 — genomics — Posted on 2020-11-16
1969 Trees and their seed networks: the social dynamics of urban fruit trees and implications for genetic diversity
Rimlinger, A.; Avana, M.-L.; Awono, A.; Chakocha, A.; Gakwavu, A.; Lemoine, T.; Marie, L.; Mboujda, F.; Vigouroux, Y.; Johnson, V.; Vinceti, B.; Carriere, S. M.; Duminil, J.
10.1101/2020.11.16.384388 — ecology — Posted on 2020-11-16
1972 ARID1A regulates R-loop associated DNA replication stress
Stirling, P.; Tsai, S.; Chang, E. Y.-C.; Fournier, L.-A.; Wells, J. P.; Minaker, S. W.; Zhu, Y. D.; Wang, A. Y.-H.; Wang, Y.; Huntsman, D. G.
10.1101/2020.11.16.384446 — cell biology — Posted on 2020-11-16
1974 Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
Das, B.; Pathak, L.; Gayan, S.; Pal, B.; Saikia, P. j.; Baishya, T.; Das, N. R.; Das, R.; Maral, M.; Mahanta, R.; Bhuyan, S.; Gautam, P.; Talukdar, J.; Sandhya, S.; Kalita, D.; Swami, V.; Das, K. R.; Bora, D. K.; Ghora, J.; Pulu, I.
10.1101/2020.11.14.382572 — immunology — Posted on 2020-11-16
1975 TEA-seq: a trimodal assay for integrated single cell measurement of transcription, epitopes, and chromatin accessibility
Swanson, E.; Lord, C.; Reading, J.; Heubeck, A. T.; Savage, A. K.; Green, R.; Li, X.-j.; Torgerson, T. R.; Bumol, T. F.; Graybuck, L. T.; Skene, P. J.
10.1101/2020.09.04.283887 — immunology — Posted on 2020-11-16
1976 Machine learning analysis of the bleomycin-mouse model reveals the compartmental and temporal inflammatory pulmonary fingerprint
Bordag, N.; Biasin, V.; Schnoegl, D.; Valzano, F.; Jandl, K.; Nagy, B. M.; Sharma, N.; Wygrecka, M.; Kwapiszewska, G.; Marsh, L. M.
10.1101/2020.05.22.106690 — immunology — Posted on 2020-11-16
1978 Conscious processing of narrative stimuli synchronizes heart rate between individuals
Perez, P.; Madsen, J.; Banellis, L.; Turker, B.; Raimondo, F.; Perlbarg, V.; Valente, M.; Nierat, M.-C.; Puybasset, L.; Naccache, L.; Similowski, T.; Cruse, D.; Parra, L. C.; SITT, J.
10.1101/2020.05.26.116079 — neuroscience — Posted on 2020-11-16
1979 Empirical field mapping for gradient nonlinearity correction of multi-site diffusion weighted MRI
Hansen, C. B.; Rogers, B. P.; Schilling, K. G.; Nath, V.; Blaber, J. A.; Irfanoglu, O.; Barnett, A.; Pierpaoli, C.; Anderson, A. W.; Landman, B. A.
10.1101/2020.05.18.102558 — neuroscience — Posted on 2020-11-16
1982 Uncovering hidden members and functions of the soil microbiome using de novo metaproteomics
Lee, J.-Y.; Mitchell, H. D.; Burnet, M. C.; Wu, R.; Jenson, S. C.; Merkley, E. D.; Nakayasu, E. S.; Nicora, C.; Jansson, J. K.; Burnum-Johnson, K. E.; Payne, S.
10.1101/428334 — bioinformatics — Posted on 2020-11-16
1987 Towards understanding predictability in ecology: A forest gap model case study
Raiho, A. M.; Dietze, M.; Dawson, A.; Rollinson, C.; Tipton, J.; McLachlan, J.
10.1101/2020.05.05.079871 — ecology — Posted on 2020-11-16
1989 The CRISPR-Cas9 crGART HeLa transcriptome: A novel cell model of de novo purine synthesis deficiency
Mazzarino, R. C.; Baresova, V.; Zikanova, M.; Duval, N.; Wilkinson, T. G.; Patterson, D.; Vacano, G. N.
10.1101/2020.06.23.167924 — cell biology — Posted on 2020-11-16
1990 Recurrent mutations in SARS-CoV-2 genomes isolated from mink point to rapid host-adaptation
van Dorp, L.; Tan, C. C.; Lam, S. D.; Richard, D.; Owen, C.; Berchtold, D.; Orengo, C.; Balloux, F.
10.1101/2020.11.16.384743 — genomics — Posted on 2020-11-16
1991 A core of functionally complementary bacteria colonizes oysters in Pacific Oyster Mortality Syndrome.
Lucasson, A.; Luo, X.; Mortaza, S.; de Lorgeril, J.; Toulza, E.; Petton, B.; Escoubas, J.-M.; Clerissi, C.; Degremont, L.; Gueguen, Y.; Destoumieux Garzon, D.; Jacq, A.; Mitta, G.
10.1101/2020.11.16.384644 — microbiology — Posted on 2020-11-16
1992 Iron can be microbially extracted from Lunar and Martian regolith simulants and 3D printed into tough structural materials
Castelein, S. M.; Aarts, T. F.; Schleppi, J.; Hendrikx, R.; Böttger, A.; Benz, D.; Marechal, M.; Makaya, A.; Brouns, S. J.; Schwentenwein, M.; Meyer, A. S.; Lehner, B. A. E.
10.1101/2020.11.15.382614 — microbiology — Posted on 2020-11-16
1993 The discriminatory power of the T cell receptor
Huhn, A.; Wilson, D. B.; van der Merwe, P. A.; Dushek, O.
10.1101/2020.11.16.384495 — immunology — Posted on 2020-11-16
1997 Analysis of SARS-CoV-2 spike glycosylation reveals shedding of a vaccine candidate
Brun, J.; Vasiljevic, S.; Gangadharan, B.; Hensen, M.; Chandran, A. V.; Hill, M. L.; Kiappes, J. L.; Dwek, R. A.; Alonzi, D. S.; Struwe, W. B.; Zitzmann, N.
10.1101/2020.11.16.384594 — biochemistry — Posted on 2020-11-16
1998 Desert Dingo (Canis lupus dingo) genome provides insights into their role in the Australian ecosystem.
Yadav, S.; Dudchenko, O.; Esvaran, M.; Rosen, B. D.; Field, M. D.; Skvortsova, K.; Edwards, R. J.; Gopalakrishnan, S.; Keilwagen, J.; Cochran, B. J.; Manandhar, B.; Bucknall, M.; Bustamante, S.; Rasmussen, J. A.; Melvin, R. G.; Omer, A.; Colaric, Z.; Chan, E. K. F.; Minoche, A. E.; Smith, T. P.; Gilbert, M. T. P.; Bogdanovic, O.; Zammit, R. A.; Thomas, T.; Aiden, E. L.; Ballard, J. W. O.
10.1101/2020.11.15.384057 — genomics — Posted on 2020-11-16
1999 DeepMosaic: Control-independent mosaic single nucleotide variant detection using deep convolutional neural networks
Yang, X.; Xu, X.; Breuss, M. W.; Antaki, D.; Ball, L. L.; Chung, C.; Li, C.; George, R. D.; Wang, Y.; Bae, T.; Abyzov, A.; Sebat, J.; Gleeson, J. G.
10.1101/2020.11.14.382473 — genomics — Posted on 2020-11-16
2001 C. elegans hermaphrodites undergo semelparous reproductive death
Kern, C. C.; Srivastava, S.; Ezcurra, M.; Hui, N.; Townsend, S.; Maczik, D.; Tse, V.; Bähler, J.; Gems, D.
10.1101/2020.11.16.384255 — genetics — Posted on 2020-11-16
2007 Trimeric SARS-CoV-2 Spike proteins produced from CHO-cells in bioreactors are high-quality antigens
Pino, P.; Kint, J.; Kiseljak, D.; Agnolon, V.; Corradin, G.; KAJAVA, A. V.; Rovero, P.; Dijkman, R.; Hartog, G. d.; McLellan, J. S.; Byrne, P.; Wurm, M. J.; Wurm, F. M.
10.1101/2020.11.15.382044 — cell biology — Posted on 2020-11-16
2008 Establishment and characterisation of primary skeletal muscle cell cultures from patients with advanced Chronic Kidney Disease
Baker, L. A.; O'Sullivan, T. F.; Robinson, K. A.; Redshaw, Z.; Graham-Brown, M.; Ashford, R. U.; Smith, A. C.; Philp, A.; Watson, E. L.
10.1101/2020.11.16.384263 — cell biology — Posted on 2020-11-16
2010 Immune Checkpoint Blockade induces peripheral cytotoxicity and persistence of large effector CD8+ T cell clones
Watson, R. A.; Tong, O.; Cooper, R. A.; Taylor, C. A.; Verge de los Aires, A.; Mahe, E.; Nassiri, I.; Middleton, M. R.; Fairfax, B. P.
10.1101/2020.11.15.383786 — immunology — Posted on 2020-11-16
2011 Divergent profiles of fentanyl withdrawal and associated pain in mice and rats
Uddin, O.; Jenne, C.; Fox, M. E.; Arakawa, K.; Keller, A.; Cramer, N. P.
10.1101/2020.11.16.384818 — neuroscience — Posted on 2020-11-16
2014 A Streptomyces venezuelae Cell-Free Toolkit for Synthetic Biology
Moore, S.; Lai, H.-E.; Chee, S.-M.; Toh, M.; Coode, S.; Capel, P.; Corre, C.; de los Santos, E.; Freemont, P.
10.1101/2020.11.16.384693 — synthetic biology — Posted on 2020-11-16
2016 Biomolecular Condensation Drives Leukemia Caused by NUP98-Fusion Proteins
Terlecki-Zaniewicz, S.; Eder, T.; Schmoellerl, J.; Humer, T.; Kuchynka, N.; Parapatics, K.; Heyes, E.; Liberante, F. G.; Müller, A. C.; Grebien, F.
10.1101/2020.11.16.384271 — cancer biology — Posted on 2020-11-16
2017 The bone microenvironment invigorates metastatic seeds for further dissemination
Zhang, W.; Bado, I. L.; Hu, J.; Wan, Y.-W.; Wu, L.; Wang, H.; Gao, Y.; Jeong, H.-H.; Xu, Z.; Hao, X.; Lege, B. M.; Al-Ouran, R.; Li, L.; Li, J.; Yu, L.; Singh, S.; Lo, H.-C.; Niu, M.; Liu, J.; Jiang, W.; Li, Y.; Wong, S. T. C.; Cheng, C.; Liu, Z.; Zhang, X. H. - F.
10.1101/2020.11.16.383828 — cancer biology — Posted on 2020-11-16
2018 A novel human fetal liver-derived model reveals that MLL-AF4 drives a distinct fetal gene expression program in infant ALL
Rice, S.; Jackson, T.; Crump, N. T.; Fordham, N.; Elliott, N.; O Byrne, S.; Inglott, S.; Ladon, D.; Wright, G.; Bartram, J.; Ancliff, P.; Mead, A. J.; Halsey, C.; Roberts, I.; Milne, T. A.; Roy, A.
10.1101/2020.11.15.379990 — cancer biology — Posted on 2020-11-16
2019 Machine learning aided top-down protein identification on a microfluidic platform
Zhang, Y.; Wright, M.; Saar, K. L.; Challa, P.; Morgunov, A. S.; Peter, Q. A. E.; Devenish, S.; Dobson, C. M.; Knowles, T. P. J.
10.1101/2020.11.14.381376 — biophysics — Posted on 2020-11-16
2020 Disclosing the actual efficiency of G-quadruplex DNA-disrupting small molecules
Mitteaux, J.; Lejault, P.; Pirrotta, M.; Wojciechowski, F.; Joubert, A.; Desbois, N.; Gros, C. P.; Hudson, R. H. E.; Boule, J.-B.; Granzhan, A.; Monchaud, D.
10.1101/2020.11.16.382176 — biophysics — Posted on 2020-11-16
2021 α-Synuclein emerges as a potent regulator of VDAC-facilitated calcium transport
Rosencrans, W. M.; Aguilella, V. M.; Rostovtseva, T. K.; Bezrukov, S. M.
10.1101/2020.11.15.383729 — biophysics — Posted on 2020-11-16
2025 Distinct hydrogenotrophic bacteria are stimulated by elevated H2 levels in upland and wetland soils
Xu, Y.; Teng, Y.; Dong, X.; Wang, X.; Zhang, C.; Ren, W.; Zhao, L.; Luo, Y.; Greening, C.
10.1101/2020.11.15.383943 — bioinformatics — Posted on 2020-11-16
2026 Mimicking the Human Tympanic Membrane: the Significance of Geometry
Anand, S.; Stoppe, T.; Lucena, M.; Rademakers, T.; Neudert, M.; Danti, S.; Moroni, L.; Mota, C.
10.1101/2020.11.14.383299 — bioengineering — Posted on 2020-11-16
2027 A Universal Allosteric Mechanism for G Protein Activation
Knight, K. M.; Ghosh, S.; Campbell, S. L.; Lefevre, T. J.; Olsen, R. H. J.; Smrcka, A. V.; Valentin, N. H.; Yin, G.; Vaidehi, N.; Dohlman, H. G.
10.1101/2020.11.15.383679 — biochemistry — Posted on 2020-11-16
2028 Selection for Decreased BRCA2 Functional Activity in Homo sapiens After Divergence from the Chimpanzee-Human Last Common Ancestor
Iacobuzio-Donahue, C. A.; Huang, J.; Zhong, Y.; Makohon-Moore, A. P.; White, T.; Jasin, M.; Norell, M. A.; Wheeler, W. C.
10.1101/2020.11.16.384677 — evolutionary biology — Posted on 2020-11-16
2031 Automatic whole cell organelle segmentation in volumetric electron microscopy
Heinrich, L.; Bennett, D.; Ackerman, D.; Park, W.; Bogovic, J.; Eckstein, N.; Petruncio, A.; Clements, J.; Xu, C. S.; Funke, J.; Korff, W.; Hess, H.; Lippincott-Schwartz, J.; Saalfeld, S.; Weigel, A.; Project Team, C.
10.1101/2020.11.14.382143 — cell biology — Posted on 2020-11-16
2035 SARS-CoV-2-specific T cell memory is long-lasting in the majority of convalsecent COVID-19 individuals
Li, Z.; Liu, J.; Deng, H.; Yang, X.; Wang, H.; Feng, X.; Zelinskyy, G.; Trilling, M.; Sutter, K.; Lu, M.; Wang, B.; Yang, D.; Zheng, X.; Liu, J.
10.1101/2020.11.15.383463 — microbiology — Posted on 2020-11-16
2036 Effects of inactivation method on SARS-CoV-2 virion proteins and structure
Loveday, E. K.; Hain, K. S.; Kochetkova, I.; Hedges, J. F.; Robison, A.; Snyder, D. T.; Brumfield, S. K.; Young, M. J.; Jutila, M. A.; Chang, C. B.; Taylor, M. P.
10.1101/2020.11.14.383026 — microbiology — Posted on 2020-11-16
2037 High resolution profiling of pathways of escape for SARS-CoV-2 spike-binding antibodies
Garrett, M. E.; Galloway, J.; Chu, H. Y.; Itell, H. L.; Stoddard, C. I.; Wolf, C. R.; Logue, J. K.; McDonald, D.; Matsen, F. A.; Overbaugh, J.
10.1101/2020.11.16.385278 — immunology — Posted on 2020-11-16
2038 Immunological memory to SARS-CoV-2 assessed for greater than six months after infection
Dan, J. M.; Mateus, J.; Kato, Y.; Hastie, K. M.; Faliti, C.; Ramirez, S. I.; Frazier, A.; Yu, E. D.; Grifoni, A.; Rawlings, S. A.; Peters, B.; Krammer, F.; Simon, V.; Saphire, E. O.; Smith, D.; Weiskopf, D.; Sette, A.; Crotty, S.
10.1101/2020.11.15.383323 — immunology — Posted on 2020-11-16
2039 DISSOCIATION BETWEEN INDIVIDUAL DIFFERENCES IN SELF-REPORTED PAIN INTENSITY AND UNDERLYING BRAIN ACTIVATION
Hoeppli, M.-E.; Nahman-Averbuch, H.; Hinkle, W. A.; Leon, E.; Peugh, J.; Lopez-Sola, M.; King, C. D.; Goldschneider, K. R.; Coghill, R. C.
10.1101/2020.11.13.381970 — neuroscience — Posted on 2020-11-16
2042 Hydrophilic Shell Matrix Proteins of Nautilus pompilius and The Identification of a Core Set of Conchiferan Domains
Setiamarga, D. H. E.; Hirota, K.; Yoshida, M.-a.; Takeda, Y.; Kito, K.; Shimizu, K.; Isowa, Y.; Ikeo, K.; Sasaki, T.; Endo, K.
10.1101/2020.11.14.382804 — zoology — Posted on 2020-11-16
2043 Novel gene-specific translation mechanism of dysregulated, chronic inflammation reveals promising, multifaceted COVID-19 therapeutics
Wang, L.; Muneer, A.; Xie, L.; Zhang, F.; Wu, B.; Mei, L.; Lenarcic, E. M.; Feng, E. H.; Song, J.; Xiong, Y.; Yu, X.; Wang, C.; Gheorghe, C.; Torralba, K.; Cook, J. G.; Wan, Y. Y.; Moorman, N. J.; Song, H.; Jin, J.; Chen, X.
10.1101/2020.11.14.382416 — systems biology — Posted on 2020-11-16
2044 Capturing in-field root system dynamics with the RootTracker
Aguilar, J. J.; Moore, M.; Johnson, L.; Greenhut, R. F.; Rogers, E.; Walker, D.; O'Neil, F.; Edwards, J. L.; Thystrup, J.; Farrow, S.; Windle, J. B.; Benfey, P. N.
10.1101/2020.11.14.382002 — plant biology — Posted on 2020-11-16
2045 Discovery of rhodomyrtone as a broad-spectrum antiviral inhibitor with anti-SARS-CoV-2 activity
Tang, W.; Lu, J.; Song, Q.-Y.; Li, M.-M.; Chen, L.-F.; Hu, L.-J.; Yang, S.-M.; Zhang, D.-M.; Wang, Y.; Li, Y.-L.; Ye, W.-C.
10.1101/2020.11.14.382770 — pharmacology and toxicology — Posted on 2020-11-16
2046 Active elimination of intestinal cells drives oncogenic growth in organoids
Krotenberg Garcia, A.; Fumagalli, A.; Quang Le, H.; Sansom, O. J.; van Rheenen, J.; Suijkerbuijk, S. J.
10.1101/2020.11.14.378588 — cancer biology — Posted on 2020-11-16
2047 The white matter is a pro-differentiative microenvironment for glioblastoma
Brooks, L. J.; Clements, M. P.; Burden, J. J.; Kocher, D.; Richards, L.; Castro Devesa, S.; Woodberry, M.; Ellis, M.; Zakka, L.; Jaunmuktane, Z.; Brandner, S.; Morrison, G.; Pollard, S. M.; Dirks, P. B.; Marguerat, S.; Parrinello, S.
10.1101/2020.11.14.379594 — cancer biology — Posted on 2020-11-16
2050 ISA API: An open platform for interoperable life science experimental metadata
Johnson, D.; Cochrane, K.; Davey, R. P.; Etuk, A.; Gonzalez-Beltran, A.; Haug, K.; Izzo, M.; Larralde, M.; Lawson, T. N.; Minotto, A.; Moreno, P.; Nainala, V. C.; O'Donovan, C.; Pireddu, L.; Roger, P.; Shaw, F.; Steinbeck, C.; Weber, R. J.; Sansone, S.-A.; Rocca-Serra, P.
10.1101/2020.11.13.382119 — bioinformatics — Posted on 2020-11-16
2051 Challenges in Benchmarking Metagenomic Profilers
Sun, Z.; Huang, S.; Zhang, M.; Zhu, Q.; Haiminen, N.; Carrieri, A.-P.; Vazquez-Baeza, Y.; Parida, L.; Kim, H.-C.; Knight, R.; Liu, Y.-Y.
10.1101/2020.11.14.382994 — bioinformatics — Posted on 2020-11-16
2053 Trecode: a FAIR eco-system for the analysis and archiving of omics data in a combined diagnostic and research setting
Kerstens, H.; Hehir-Kwa, J.; van de Geer-de Jong, E.; van Run, C.; Verwiel, E.; van der Leest, D.; Tops, B.; Kemmeren, P.
10.1101/2020.11.13.363689 — bioinformatics — Posted on 2020-11-16
2057 Self-organization and culture of Mesenchymal Stromal Cell spheroids in acoustic levitation
Jeger-Madiot, N.; Arakelian, L.; Setterblad, N.; Bruneval, P.; Hoyos, M.; Larghero, J.; Aider, J.-L.
10.1101/2020.11.16.385047 — bioengineering — Posted on 2020-11-16
2058 Single-nuclei RNA-sequencing of plants
Sunaga-Franze, D. Y.; Muino, J.; Braeuning, C.; Xu, X.; Zong, M.; Smaczniak, C.; Yan, W.; Fischer, C.; Vidal, R.; Kliem, M.; Kaufmann, K.; Sauer, S.
10.1101/2020.11.14.382812 — genomics — Posted on 2020-11-16
2059 Combining climatic and genomic data improves range-wide tree height growth prediction in a forest tree
Archambeau, J.; Benito Garzon, M.; Barraquand, F.; de Miguel Vega, M.; Plomion, C.; C. Gonzalez-Martinez, S.
10.1101/2020.11.13.382515 — genetics — Posted on 2020-11-16
2060 Solving the sex ratio scandal in Melittobia wasps
Abe, J.; Iritani, R.; Tsuchida, K.; Kamimura, Y.; West, S. A.
10.1101/2020.11.16.384768 — evolutionary biology — Posted on 2020-11-16
2061 Measuring diversity from space: a global view of the free and open source rasterdiv R package under a coding perspective
Thouverai, E.; Marcantonio, M.; Bacaro, G.; Da Re, D.; Iannacito, M.; Ricotta, C.; Tattoni, C.; Vicario, S.; Rocchini, D.
10.1101/2020.11.14.369371 — ecology — Posted on 2020-11-16
2063 Bacterial density as an unexpected factor regulating decomposition by soil oligotrophs
Coche, A. W.; Babey, T.; Rapaport, A.; Vieuble Gonod, L.; Garnier, P.; Nunan, N.; de Dreuzy, J. R.
10.1101/2020.11.16.384735 — ecology — Posted on 2020-11-16
2073 Interpretable Segmentation of Amyloid-βStained Whole Slide Images of Brain Tissue
Lai, Z.; Guo, R.; Xu, W.; Hu, Z.; Mifflin, K.; Dugger, B. N.; Cheung, S.-c.; Chuah, C.-N.
10.1101/2020.11.13.381871 — neuroscience — Posted on 2020-11-16
2074 Identification of an endocannabinoid gut-brain vagal mechanism controlling food reward and energy homeostasis
Berland, C.; Castel, J.; Montalban, E.; Foppen, E.; Martin, C.; Muccioli, G. G.; Luquet, S.; Gangarossa, G.
10.1101/2020.11.14.382291 — neuroscience — Posted on 2020-11-16
2076 A computational neural model for mapping degenerate neural architectures
Khan, Z.; Wang, Y.; Sennesh, E. Z.; Dy, J.; Ostadabbas, S.; van de Meent, J.-W.; Hutchinson, J. B.; Satpute, A. B.
10.1101/2020.11.13.382192 — neuroscience — Posted on 2020-11-16
2077 The distinct roles of calcium in rapid control of neuronal glycolysis and the tricarboxylic acid cycle
Diaz-Garcia, C. M.; Meyer, D. J.; Nathwani, N.; Rahman, M.; Martinez-Francois, J. R.; Yellen, G.
10.1101/2020.11.16.385526 — neuroscience — Posted on 2020-11-16
2078 Mutations in the juxtamembrane segment of the cholesterol-binding site of APP alter its processing and promotes production of shorter, less toxic Aβ peptides.
Hanbouch, L.; Schaack, B.; Kasri, A.; Fontaine, G.; Gkanatsiou, E.; Brinkmalm, G.; Portelius, E.; Blennow, K.; Mourier, G.; Gilles, N.; Millan, M. J.; Marquer, C.; Zetterberg, H.; Boussicault, L.; Potier, M.-C.
10.1101/2020.11.16.384891 — neuroscience — Posted on 2020-11-16
2082 Inherent population structure determines the importance of filtering parameters for reduced representation sequencing analyses
Selechnik, D.; Richardson, M. F.; Hess, M.; Hess, A. S.; Dodds, K. G.; Martin, M.; Chan, T. C.; Cardilini, A. P. A.; Sherman, C.; Shine, R.; Rollins, L. A.
10.1101/2020.11.14.383240 — bioinformatics — Posted on 2020-11-16
2091 A freeze-and-thaw induced-fragment of the microtubule-associated protein Tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity
Vasconcelos, I. C.; Campos, R. M. d.; Schwaemmle, H. M. K.; Masson, A. P.; Ferrari, G. D.; Alberici, L. C.; Faca, V. M.; Garcia-Cairasco, N.; Sebollela, A. S.
10.1101/404129 — biochemistry — Posted on 2020-11-16
2092 The translational landscape of SARS-CoV-2 and infected cells
Puray-Chavez, M.; Tenneti, K.; Vuong, H. R.; Lee, N.; Liu, Y.; Horani, A.; Huang, T.; Gunsten, S. P.; Case, J. B.; Yang, W.; Diamond, M. S.; Brody, S. L.; Dougherty, J.; Kutluay, S. B.
10.1101/2020.11.03.367516 — microbiology — Posted on 2020-11-16
2093 Stenoparib, an inhibitor of cellular poly (ADP-ribose) polymerase (PARP), blocks replication of the SARS-CoV-2 human coronavirus in vitro.
Stone, N. E.; Jaramillo, S. A.; Jones, A. N.; Vazquez, A. J.; Martz, M.; Versluis, L. M.; Raniere, M. O.; Nunnally, H. E.; Zarn, K. E.; Nottingham, R.; Sahl, J. W.; Wagner, D. M.; Knudsen, S.; Settles, E. W.; Keim, P. S.; French, C. T.
10.1101/2020.11.12.380394 — microbiology — Posted on 2020-11-16
2094 Large-scale monitoring of resistance to coumaphos, amitraz and pyrethroids in Varroa destructor
Hernandez-Rodriguez, C. S.; Marin, O.; Calatayud, F.; Mahiques, M. J.; Mompo, A.; Segura, I.; Simo, E.; Gonzalez-Cabrera, J.
10.1101/2020.11.12.378190 — pharmacology and toxicology — Posted on 2020-11-16
2096 European Primary Forest Database (EPFD) v2.0
Sabatini, F. M.; Bluhm, H.; Kun, Z.; Aksenov, D.; Atauri, J. A.; Buchwald, E.; Burrascano, S.; Cateau, E.; Diku, A.; Marques Duarte, I.; Fernandez Lopez, A. B.; Garbarino, M.; Grigoriadis, N.; Horvath, F.; Keren, S.; Kitenberga, M.; Kis, A.; Kraut, A.; Ibisch, P. L.; Larrieu, L.; Lombardi, F.; Matovic, B.; Melu, R. N.; Meyer, P.; Midteng, R.; Mikac, S.; Mikolas, M.; Mozgeris, G.; Panayotov, M.; Pisek, R.; Nunes, L.; Ruete, A.; Schickhofer, M.; Simovski, B.; Stillhard, J.; Stojanovic, D.; Szwagrzyk, J.; Tikkanen, O.-P.; Toromani, E.; Volosyanchuk, R.; Vrska, T.; Waldherr, M.; Yermokhin, M.; Zla
10.1101/2020.10.30.362434 — ecology — Posted on 2020-11-16
2099 Loss of ASH1L in developing brains causes autistic-like behaviors in a mouse model
Gao, Y.; Duque-Wilckens, N.; Aljazi, M. B.; Wu, Y.; Moeser, A. J.; Mias, G. I.; Robison, A. J.; He, J.
10.1101/2020.11.16.377259 — neuroscience — Posted on 2020-11-16
2101 Measuring protected-area outcomes with leech iDNA: large-scale quantification of vertebrate biodiversity in Ailaoshan reserve
Ji, Y.; Baker, C. C.; Li, Y.; Popescu, V. D.; Wang, Z.; Wang, J.; Wang, L.; Wu, C.; Hua, C.; Yang, Z.; Yang, C.; Xu, C. C.; Wen, Q.; Pierce, N. E.; Yu, D. W.
10.1101/2020.02.10.941336 — ecology — Posted on 2020-11-16
2102 Thalamic spontaneous activity coordinates the timing of corticothalamic innervation in the visual system
Lopez-Bendito, G.; Moreno-Juan, V.; Martini, F.; Perez-Saiz, L.; Vadeolmillos, M.; Herrero-Navarro, A.
10.1101/2020.11.13.382366 — neuroscience — Posted on 2020-11-16
2104 Rapid HIV-1 capsid interaction screening using fluorescence fluctuationspectroscopy
Lau, D.; Walsh, J. C.; Dickson, C. F.; Tuckwell, A.; Stear, J. H.; Hunter, D. J. B.; Bhumkar, A.; Shah, V.; Turville, S. G.; Sierecki, E.; Gambin, Y.; Jacques, D. A.; Böcking, T.
10.1101/2020.11.13.382242 — biophysics — Posted on 2020-11-16
2106 Transmission and antibiotic resistance of Achromobacter in cystic fibrosis
Gabrielaite, M.; Bartell, J. A.; Norskov-Lauritsen, N.; Pressler, T.; Nielsen, F. C.; Johansen, H. K.; Marvig, R. L.
10.1101/2020.08.04.235952 — genomics — Posted on 2020-11-16
2107 Deep learning and automated Cell Painting reveal Parkinson's disease-specific signatures in primary patient fibroblasts
Schiff, L.; Migliori, B.; Chen, Y.; Carter, D.; Bonilla, C.; Hall, J.; Fan, M.; Tam, E.; Ahadi, S.; Fischbacher, B.; Geraschenko, A.; Hunter, C. J.; Venugopalan, S.; DesMarteau, S.; Narayanaswamy, A.; Jacob, S.; Armstrong, Z.; Ferrarotto, P.; Williams, B.; Buckley-Herd, G.; Hazard, J.; Goldberg, J.; Coram, M.; Otto, R.; Baltz, E. A.; Andres-Martin, L.; Pritchard, O.; Duren-Lubanski, A.; Reggio, K.; Global Stem Cell Array Team, N.; Bauer, L.; Aiyar, R. S.; Schwarzbach, E.; Paull, D.; Noggle, S. A.; Monsma, F. J.; Berndl, M.; Yang, S. J.; Johannesson, B.
10.1101/2020.11.13.380576 — cell biology — Posted on 2020-11-16
2108 GJA1 Depletion Causes Ciliary Defects by Affecting Rab11 Trafficking to the Ciliary Base
Jang, D. G.; Kwon, K. Y.; Kweon, Y. C.; Kim, B.-g.; Myung, K.; Lee, H.-S.; Young Park, C.; Kwon, T.; Park, T. J.
10.1101/2020.11.13.381764 — cell biology — Posted on 2020-11-16
2109 An Entropic Safety Catch Controls Hepatitis C Virus Entry and Antibody Resistance.
Stejskal, L.; Kalemera, M. D.; Palor, M.; Walker, L.; Daviter, T.; Lees, W. D.; Moss, D. S.; Kremyda-Vlachou, M.; Kozlakidis, Z.; Rosenberg, W.; Illingworth, C. J. R.; Shepherd, A. J.; Grove, J.
10.1101/2020.11.11.377218 — molecular biology — Posted on 2020-11-16
2110 The cell fate controlling CLE40 peptide requires CNGC9 to trigger highly localized Ca2+ transients in Arabidopsis thaliana root meristems
Breiden, M.; Olsson, V.; Gustavo Pinto, K.; Bluemke, P.; Denay, G.; Schlegel, J.; Dietrich, P.; Butenko, M. A.; Simon, R.
10.1101/2020.11.13.381111 — plant biology — Posted on 2020-11-16
2113 The role of microglia membrane potential in chemotaxis
Laprell, L.; Schulze, C.; Brehme, M.-L.; Oertner, T. G.
10.1101/2020.05.19.104109 — neuroscience — Posted on 2020-11-16
2114 A Bayesian semi-parametric model for thermal proteome profiling
Fang, S.; Kirk, P. D.; Bantscheff, M.; Lilley, K. S.; Crook, O.
10.1101/2020.11.14.382747 — systems biology — Posted on 2020-11-16
2115 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-16
2117 Gene-environment interactions in Multiple Sclerosis: a UK Biobank study
Jacobs, B. M.; Noyce, A.; Bestwick, J. P.; Belete, D.; Giovannoni, G.; Dobson, R.
10.1101/2020.03.01.971739 — genetics — Posted on 2020-11-16
2119 Characterizing the Emergence of Liver and Gallbladder from the Embryonic Endoderm through Single-Cell RNA-Seq
Mu, T.; Xu, L.; Zhong, Y.; Liu, X.; Zhao, Z.; Huang, C.; Lan, X.; Lufei, C.; Zhou, Y.; Su, Y.; Xu, L.; Jiang, M.; Zhou, H.; Lin, X.; Wu, L.; Peng, S.; Liu, S.; Pedersen, S. B.; Dean, M.; Dunn, N. R.; Zaret, K. S.; Fu, X.-Y.; Hou, Y.
10.1101/718775 — developmental biology — Posted on 2020-11-16
2120 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-16
2123 DIPPER: a spatiotemporal proteomics atlas of human intervertebral discs for exploring dynamic changes in health, ageing and degeneration
Tam, V.; Chen, P.; Yee, A.; Solis, N.; Klein, T.; Kudelko, M.; Sharma, R.; Chan, W. C.; Overall, C. M.; Haglund, L.; Sham, P. C.; Cheah, K. S.; Chan, D.
10.1101/2020.07.11.192948 — systems biology — Posted on 2020-11-16
2125 C. elegans provide milk for their young
Kern, C. C.; Townsend, S.; Salzmann, A.; Rendell, N. B.; Taylor, G. W.; Comisel, R. M.; Foukas, L. C.; Bähler, J.; Gems, D.
10.1101/2020.11.15.380253 — genetics — Posted on 2020-11-15
2126 A Bayesian semi-parametric model for thermal proteome profiling
Fang, S.; Kirk, P. D.; Bantscheff, M.; Lilley, K. S.; Crook, O.
10.1101/2020.11.14.382747 — systems biology — Posted on 2020-11-15
2129 CRISPAltRations: a validated cloud-based approach for interrogation of double-strand break repair mediated by CRISPR genome editing
Kurgan, G.; Turk, R.; Li, H.; Rettig, G. R.; Jacobi, A. M.; Tso, L.; Mertens, M.; Noten, R.; Florus, K.; Behlke, M. A.; Wang, Y.; McNeill, M. S.
10.1101/2020.11.13.382283 — bioinformatics — Posted on 2020-11-15
2134 Phenotypic and Genetic Markers of Psychopathology in a Population-Based Sample of Older Adults
Gard, A. M. S.; Ware, E. B.; Hyde, L. W.; Schmitz, L.; Faul, J.; Mitchell, C.
10.1101/601609 — genomics — Posted on 2020-11-15
2136 Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-11-15
2140 Phenotypic plasticity of ER+ breast cancer in the bone microenvironment
Bado, I. L.; Wang, H.; Hu, J.; Sarkar, P.; Liu, J.; Gugala, Z.; Xu, Z.; Zhang, W.; Wu, W.; Lo, H.-C.; Li, L.; Kim, I.-S.; Singh, S.; Janghorban, M.; Muscallera, A.; Goldstein, A.; Singh, P.; Jeong, H. H.; Wan, Y.-W.; Shixia, H.; Schiff, R.; Waleed, G. M.; Liu, Z.; Ellis, M. J.; Zhang, X. H. F.
10.1101/2020.11.14.383000 — cancer biology — Posted on 2020-11-15
2145 Identification of novel Alzheimer's disease genes co-expressed with TREM2
Reddy, J. S.; Allen, M.; Wang, X.; Biernacka, J. M.; Coombes, B. J.; Jenkins, G. D.; Sinnwell, J. P.; Carrasquillo, M. M.; Pottier, C. P.; Ren, Y.; Sarangi, V.; Younkin, C. S.; Asmann, Y. W.; Ross, O. A.; Rademakers, R.; Golde, T. E.; Ertekin-Taner, N.; Steven, Y. G.
10.1101/2020.11.13.381640 — genetics — Posted on 2020-11-15
2146 Linking biotic homogenisation with large-scale changes of species associations
Rigal, S.; Devictor, V.; Gaüzere, P.; Kefi, S.; Forsman, J. T.; Kajanus, M. H.; Mönkkönen, M.; Dakos, V.
10.1101/2020.11.13.380956 — ecology — Posted on 2020-11-15
2147 Uncoordinated long-patch base excision repair at juxtaposed DNA lesions generates a lethal accumulation of double-strand breaks
Shimada, K.; Van Loon, B.; Gerhold, C. B.; Bregenhorn, S.; Hurst, V.; Tarashev, C.; Roth, G.; Heinis, C.; Jiricny, J.; Gasser, S. M.
10.1101/2020.11.15.383513 — molecular biology — Posted on 2020-11-15
2152 Computational characteristics of interictal EEG as objective markers of epileptic spasms
Smith, R. J.; Hu, D. K.; Shrey, D. W.; Rajaraman, R.; Hussain, S. A.; Lopour, B. A.
10.1101/2020.11.13.380691 — neuroscience — Posted on 2020-11-15
2154 Multiple types of navigational information are independently encoded in the population activities of the dentate gyrus neurons
Murano, T.; Nakajima, R.; Nakao, A.; Hirata, N.; Amemori, S.; Murakami, A.; Kamitani, Y.; Yamamoto, J.; Miyakawa, T.
10.1101/2020.06.09.141572 — neuroscience — Posted on 2020-11-15
2158 Brain disconnectivity mapping of post-stroke fatigue
Ulrichsen, K. M.; Kolskaar, K. K.; Richard, G.; Alnaes, D.; Dorum, E. S.; Sanders, A.-M.; Tornaas, S.; Sanchez, J. M.; Engvig, A.; Ihle-Hansen, H.; Thiebaut de Schotten, M.; Nordvik, J. E.; Westlye, L. T.
10.1101/2020.11.13.380972 — neuroscience — Posted on 2020-11-15
2160 Stimulus-specific plasticity of macaque V1 spike rates and gamma
Peter, A. S.; Stauch, B. J.; Shapcott, K.; Kouroupaki, K.; Schmiedt, J. T.; Klein, L.; Klon-Lipok, J.; Dowdall, J. R.; Schoelvinck, M. L.; Vinck, M.; Singer, W.; Schmid, M. C.; Fries, P.
10.1101/2020.11.13.381418 — neuroscience — Posted on 2020-11-15
2161 Nutrient signaling pathways regulate amyloid clearance and synaptic loss in Alzheimer's disease
Mondal, M.; Bali, J.; Tzioras, M.; Paolicelli, R. C.; Malnar, M.; Dominko, K.; Jawaid, A.; Udayar, V.; Ben Halima, S.; Vadodaria, K. C.; Manesso, E.; Thakur, G.; Decressac, M.; Petit, C.; Sudharshan, R.; Hecimovic, S.; Simons, M.; Klumperman, J.; Bruestle, O.; Ferguson, S.; Nitsch, R.; Schulz, P. E.; Spires-Jones, T. L.; Koch, P.; Gunawan, R.; Rajendran, L.
10.1101/2020.11.13.381186 — neuroscience — Posted on 2020-11-15
2162 The single pass membrane protein MRAP2 regulates energy homeostasis by promoting primary cilia localization of the G protein-coupled receptor MC4R
Bernard, A. A.; Ojeda Naharros, I.; Bourgain-Guglielmetti, F.; Ciprin, J.; Yue, X.; Zhang, S.; McDaid, E.; Nachury, M. V.; Reiter, J.; Vaisse, C.
10.1101/2020.11.13.382325 — neuroscience — Posted on 2020-11-15
2163 High-resolution transcriptome atlas and improved genome assembly of common buckwheat, Fagopyrum esculentum
Penin, A. A.; Kasianov, A. S.; Klepikova, A. V.; Kirov, I. V.; Gerasimov, E. S.; Fesenko, A. N.; Logacheva, M. D.
10.1101/2020.11.14.382903 — plant biology — Posted on 2020-11-15
2167 The spliceosome inhibitors isoginkgetin and pladienolide B induce ATF3-dependent cell death
Vanzyl, E. J.; Sayed, H.; Blackmore, A. B.; Rick, K. R. C.; Fernando, P.; McKay, B. C.
10.1101/821363 — cell biology — Posted on 2020-11-15
2169 Cold-associated mammokines preserve adipocyte identity
Santos, L. C.; Arneson, D.; Chella Krishnan, K.; Ahn, I. S.; Diamante, G.; Cely, I.; Butte, A. J.; Lusis, A. J.; Yang, X.; Rajbhandari, P.
10.1101/2020.11.14.378687 — cell biology — Posted on 2020-11-15
2171 Tobramycin adaptation enhances policing of social cheaters in Pseudomonas aeruginosa
Abisado, R.; Kimbrough, J. H.; McKee, B. M.; Craddock, V.; Smalley, N.; Dandekar, A. A.; Chandler, J. R.
10.1101/2020.11.15.383836 — microbiology — Posted on 2020-11-15
2175 T cells exhibit unexpectedly low discriminatory power and can respond to ultra-low affinity peptide-MHC ligands
Pettmann, J.; Abu-Shah, E.; Kutuzov, M.; Wilson, D. B.; Dustin, M.; Davis, S.; van der Merwe, P. A.; Dushek, O.
10.1101/2020.11.14.382630 — immunology — Posted on 2020-11-15
2176 Stem cell basis of a host driven transmission of antigen packed aerosols: a novel mechanism of natural vaccination for tuberculosis
Das, B.; Pathak, L.; Gayan, S.; Pal, B.; Saikia, P. j.; Baishya, T.; Das, N. R.; Das, R.; Maral, M.; Mahanta, R.; Bhuyan, S.; Gautam, P.; Talukdar, J.; Sandhya, S.; Kalita, D.; Swami, V.; Das, K. R.; Bora, D. K.; Ghora, J.; Pulu, I.
10.1101/2020.11.14.382572 — immunology — Posted on 2020-11-15
2177 Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience
Chang, L. J.; Jolly, E.; Cheong, J. H.; Rapuano, K.; Greenstein, N.; Chen, P.-H. A.; Manning, J. R.
10.1101/487892 — neuroscience — Posted on 2020-11-15
2178 Saccadic modulation of neural activity in the human anterior thalamus during visual active sensing
Leszczynski, M.; Staudigl, T.; Chaieb, L.; Enkirch, S. J.; Fell, J.; Schroeder, C. E.
10.1101/2020.03.30.015628 — neuroscience — Posted on 2020-11-15
2183 Anatomic position determines oncogenic specificity in melanoma
Weiss, J. M.; Hunter, M. V.; Tagore, M.; Ma, Y.; Misale, S.; Simon-Vermot, T.; Campbell, N. R.; Newell, F.; Wilmott, J. S.; Johansson, P. A.; Thompson, J. F.; Long, G. V.; Pearson, J. V.; Mann, G. J.; Scolyer, R. A.; Waddell, N.; Montal, E. D.; Huang, T.-H.; Jonsson, P.; Donoghue, M. T. A.; Harris, C. C.; Taylor, B. S.; Ariyan, C. E.; Solit, D. B.; Wolchok, J. D.; Merghoub, T.; Rosen, N.; Hayward, N. K.; White, R. M.
10.1101/2020.11.14.383083 — cancer biology — Posted on 2020-11-15
2186 precisionFDA Truth Challenge V2: Calling variants from short- and long-reads in difficult-to-map regions
Olson, N. D.; Wagner, J.; McDaniel, J.; Stephens, S. H.; Westreich, S. T.; Prasanna, A. G.; Johanson, E.; Boja, E.; Maier, E. J.; Serang, O.; Jaspez, D.; Lorenzo-Salazar, J. M.; Munoz-Barrera, A.; Rubio-Rodriguez, L. A.; Flores, C.; Kyriakidis, K.; Malousi, A.; Shafin, K.; Pesout, T.; Jain, M.; Paten, B.; Chang, P.-C.; Kolesnikov, A.; Nattestad, M.; Baid, G.; Goel, S.; Yang, H.; Carroll, A.; Eveleigh, R.; Bourgey, M.; Bourque, G.; Li, G.; MA, C.; Tang, L.; DU, Y.; Zhang, S.; Morata, J.; Tonda, R.; Parra, G.; Trotta, J.-R.; Brueffer, C.; Demirkaya-Budak, S.; Kabakci-Zorlu, D.; Turgut, D.; Kalay
10.1101/2020.11.13.380741 — bioinformatics — Posted on 2020-11-15
2187 Nuclear lamin A/C promotes cancer cell survival and lung metastasis without restricting transendothelial migration
Roncato, F.; Regev, O.; Feigelson, S. W.; Yadav, S. K.; Kaczmarczyk, L.; Levi, N.; Drago-Garcia, D.; Ovadia, S.; Kizner, M.; Addadi, Y.; Sabino, J. C.; Ovadya, Y.; de Almeida, S. F.; Feldmesser, E.; Gerlitz, G.; Alon, R.
10.1101/2020.06.23.167130 — cancer biology — Posted on 2020-11-15
2189 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-15
2190 Adipose-tissue derived signals control bone remodelling.
Madel, M.-B.; Fu, H.; Pierroz, D.; Schiffrin, M.; Winkler, C.; Wilson, A.; Pochon, C.; Toffoli, B.; Jouzeau, J.-Y.; Gilardi, F.; Ferrari, S.; Bonnet, N.; BLIN-WAKKACH, C.; Desvergne, B.; MOULIN, D.
10.1101/2020.03.02.972711 — cell biology — Posted on 2020-11-15
2192 Fra1 is required for TGFβ1 induced collective invasion
Camacho, S.; Nasir, A.; Rahhal, R.; Dominguez, M.; Pearson, G. W.
10.1101/2020.11.14.383232 — cancer biology — Posted on 2020-11-15
2194 The primary cilium is required for MC4R control of food intake and body weight
Wang, Y.; Bernard, A. A.; Comblain, F.; Yue, X.; Paillart, C.; Zhang, S.; Reiter, J.; Vaisse, C.
10.1101/2020.11.13.382234 — physiology — Posted on 2020-11-15
2195 Single-femtosecond atomic-resolution observation of a protein traversing a conical intersection
Hosseinizadeh, A.; Breckwoldt, N.; Fung, R.; Sepehr, R.; Schmidt, M.; Schwander, P.; Santra, R.; Ourmazd, A.
10.1101/2020.11.13.382218 — biophysics — Posted on 2020-11-15
2203 Decreasing pdzd8-mediated mitochondrial-ER contacts in neurons improves fitness by increasing mitophagy
Hewitt, V. L.; Miller-Fleming, L.; Andreazza, S.; Mattedi, F.; Prudent, J.; Polleux, F.; Vagnoni, A.; Whitworth, A. J.
10.1101/2020.11.14.382861 — cell biology — Posted on 2020-11-15
2204 Cold-associated mammokines preserve adipocyte identity
Santos, L. C.; Arneson, D.; Chella Krishnan, K.; Ahn, I. S.; Diamante, G.; Cely, I.; Butte, A. J.; Yang, X.; Lusis, A. J.; Rajbhandari, P.
10.1101/2020.11.14.378687 — cell biology — Posted on 2020-11-15
2207 Template-independent genome editing and repairing correct frameshift disease in vivo
Liu, L.; Li, K.; Zou, L.; Hou, H.; Hu, Q.; Liu, S.; Wang, S.; Wang, Y.; Li, J.; Song, C.; Chen, J.; Li, C.; Du, H.; Li, J.-L.; Chen, F.; Xu, Z.; Sun, W.; Sun, Q.; Xiong, W.
10.1101/2020.11.13.381160 — neuroscience — Posted on 2020-11-15
2208 Upregulated functionality of mitochondria-associated ER membranes in a mouse model of traumatic brain injury
Agrawal, R. R.; Larrea, D.; Shi, L.; Song, D.; Xu, Y.; Yun, T. D.; Emmanuele, V.; Cummins, L. G.; Macaluso, F. P.; Kernie, S. G.; Min, W.; Deckelbaum, R. J.; Area-Gomez, E.
10.1101/2020.11.13.381756 — neuroscience — Posted on 2020-11-15
2209 PSD-95 in dorsal CA1 contributes to the persistence of fear memory
Ziolkowska, M.; Borczyk, M.; Nowacka, A.; Nalberczak-Skora, M.; Sliwinska, M. A.; Robaca, M.; Lukasiewicz, K.; Caly, A.; Skonieczna, E.; Tomaszewski, K. F.; Wojtowicz, T.; Wlodarczyk, J.; Bernas, T.; Salamian, A.; Radwanska, K.
10.1101/2020.11.13.381368 — neuroscience — Posted on 2020-11-15
2213 A high-quality, chromosome-level genome assembly of the Black Soldier Fly (Hermetia Illucens L.)
Generalovic, T. N.; McCarthy, S. A.; Warren, I. A.; Wood, J. M. D.; Torrance, J.; Sims, Y.; Quail, M.; Howe, K.; Pipan, M.; Durbin, R.; Jiggins, C. D.
10.1101/2020.11.13.381889 — genomics — Posted on 2020-11-15
2214 Genome-wide Identification of the Genetic Basis of Amyotrophic Lateral Sclerosis
Zhang, S.; Cooper-Knock, J.; Weimer, A. K.; Shi, M.; Moll, T.; Harvey, C.; Nezhad, H. G.; Franklin, J.; Souza, C. d. S.; Wang, C.; Li, J.; Eitan, C.; Hornstein, E.; Kenna, K. P.; Project MinE Sequencing Consortium, ; Veldink, J.; Ferraiuolo, L.; Shaw, P. J.; Snyder, M. P.
10.1101/2020.11.14.382606 — genomics — Posted on 2020-11-15
2215 Predicting future from past: The genomic basis of recurrent and rapid stickleback evolution
Roberts Kingman, G. A.; Vyas, D. N.; Jones, F. C.; Brady, S. D.; Chen, H. I.; Reid, K.; Millhaven, M.; Bertino, T. S.; Aguirre, W. E.; Heins, D. C.; von Hippel, F. A.; Park, P. J.; Kirch, M.; Absher, D.; Myers, R. M.; Di Palma, F.; Bell, M. A.; Kingsley, D. M.; Veeramah, K. R.
10.1101/2020.11.13.382424 — evolutionary biology — Posted on 2020-11-15
2218 3D architecture and structural flexibility revealed in the subfamily of large glutamate dehydrogenases by a mycobacterial enzyme
Lazaro, M.; Melero, R.; Huet, C.; Lopez-Alonso, J. P.; Delgado, S.; Dodu, A.; Bruch, E. M.; Abriata, L. A.; Alzari, P. M.; Valle, M.; Lisa, M.-N.
10.1101/2020.11.14.381715 — microbiology — Posted on 2020-11-15
2220 Far-red fluorescent genetically encoded calcium ion indicators
Dalangin, R.; Drobizhev, M.; Molina, R. S.; Aggarwal, A.; Patel, R.; Abdelfattah, A. S.; Zhao, Y.; Wu, J.; Podgorski, K.; Schreiter, E. R.; Hughes, T. E.; Campbell, R. E.; Shen, Y.
10.1101/2020.11.12.380089 — neuroscience — Posted on 2020-11-15
2221 Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins
Uemura, T.; Suzuki, E.; Kawase, S.; Kurihara, T.; Yasumura, M.; Yoshida, T.; Fukai, S.; Yamazaki, M.; Fei, P.; Abe, M.; Watanabe, M.; Sakimura, K.; Mishina, M.; Tabuchi, K.
10.1101/2020.11.14.383158 — neuroscience — Posted on 2020-11-15
2225 X-ray Irradiation activates immune response in human T-lymphocytes by eliciting a Ca2+ signaling cascade
Thiel, G.; Tandl, D. H.; Sponagel, T.; Fuck, S.; Smit, T.; Hehlgans, S.; Jakob, B.; Fournier, C.; Roedel, F.; Roth, B.; Moroni, A.
10.1101/2020.11.13.379982 — biophysics — Posted on 2020-11-15
2229 Hidden cell diversity in Placozoa: Ultrastructural Insights from Hoilungia hongkongensis
Romanova, D. Y.; Varoqueaux, F.; Daraspe, J.; Nikitin, M. A.; Eitel, M.; Fasshauer, D.; Moroz, L. L.
10.1101/2020.11.13.382382 — evolutionary biology — Posted on 2020-11-14
2231 Exploring correlations in cultural and genetic variation across language families in Northeast Asia
Matsumae, H.; Ranacher, P.; Savage, P. E.; Blasi, D. E.; Currie, T. E.; Koganebuchi, K.; Tanabe, H.; Sato, T.; Nishida, N.; Tajima, A.; Brown, S.; Stoneking, M.; Shimizu, K. K. K.; Oota, H.; Bickel, B.
10.1101/513929 — evolutionary biology — Posted on 2020-11-14
2234 Interdependence of CTL and NK cells cytotoxicity against melanoma cells
Friedmann, K. S.; Knoerck, A.; Cappello, S.; Hoxha, C.; Schwaer, G.; Iden, S.; Bogeski, I.; Kummerow, C.; Schwarz, E. C.; Hoth, M.
10.1101/2020.06.14.150672 — immunology — Posted on 2020-11-14
2235 A Pig White Matter Atlas and Common Connectivity Space Provide a Roadmap for the Introduction of a New Animal Model in Translational Neuroscience
Benn, R. A.; Mars, R. B.; Xu, T.; Rodriguez-Esparragoza, L.; Montesinos, P.; Manzano-Patron, J. P.; Lopez-Martin, G.; Fuster, V.; Sanchez-Gonzalez, J.; Duff, E. P.; Ibanez, B.
10.1101/2020.10.13.337436 — neuroscience — Posted on 2020-11-14
2236 Neural Fragility as an EEG Marker of the Seizure Onset Zone
Li, A.; Huynh, C.; Fitzgerald, Z.; Cajigas, I.; Brusko, D.; Claudio, A.; Jagid, J.; Kanner, A.; Hopp, J.; Chen, S.; Haagensen, J.; Johnson, E.; Crone, N.; Anderson, W.; Inati, S.; Zaghloul, K.; Bulacio, J.; Martinez, J.; Sarma, S.
10.1101/862797 — neuroscience — Posted on 2020-11-14
2245 Proteomics characterisation of the L929 cell supernatant and its role in BMDM differentiation
Heap, R. E.; Marin Rubio, J. L.; Peltier, J.; Heunis, T.; Dannoura, A.; Moore, A.; Trost, M.
10.1101/2020.08.20.259515 — immunology — Posted on 2020-11-14
2247 Intracranial recordings from human auditory cortex reveal a neural population selective for musical song
Norman-Haignere, S.; Feather, J.; Boebinger, D.; Brunner, P.; Ritaccio, A.; McDermott, J. H.; Schalk, G.; Kanwisher, N.
10.1101/696161 — neuroscience — Posted on 2020-11-14
2249 GeneBreaker: Variant simulation to improve the diagnosis of Mendelian rare genetic diseases
Richmond, P. A.; Av-Shalom, T. V.; Fornes, O.; Modi, B.; Elliott, A. M.; Wasserman, W. W.
10.1101/2020.05.29.124495 — genomics — Posted on 2020-11-14
2251 Endogenous variation in ventromedial prefrontal cortex state dynamics during naturalistic viewing reflects affective experience
Chang, L. J.; Jolly, E.; Cheong, J. H.; Rapuano, K.; Greenstein, N.; Chen, P.-H. A.; Manning, J. R.
10.1101/487892 — neuroscience — Posted on 2020-11-14
2252 Analysis of the Dynamics and Distribution of SARS-CoV-2 Mutations and its Possible Structural and Functional Implications
Justo Arevalo, S.; Zapata Sifuentes, D.; Huallpa Robles, C.; Landa Bianchi, G.; Castillo Chavez, A.; Garavito-Salini Casas, R.; Pineda Chavarria, R.; Uceda-Campos, G.
10.1101/2020.11.13.381228 — genomics — Posted on 2020-11-14
2253 A comparison of DNA/RNA extraction protocols for high-throughput sequencing of microbial communities
Shaffer, J. P.; Marotz, C.; Belda-Ferre, P.; Martino, C.; Wandro, S.; Estaki, M.; Salido, R. A.; Carpenter, C. S.; Zaramela, L. S.; Minich, J. J.; Bryant, M. B.; Sanders, K.; Fraraccio, S.; Ackermann, G.; Humphrey, G.; Swafford, A. D.; Miller-Montgomery, S.; Knight, R.
10.1101/2020.11.13.370387 — ecology — Posted on 2020-11-14
2254 Isotropic 3D electron microscopy reference library of whole cells and tissues
Xu, C. S.; Pang, S.; Shtengel, G.; Müller, A.; Ritter, A. T.; Hoffman, H. K.; Takemura, S.-y.; Lu, Z.; Pasolli, H. A.; Iyer, N.; Chung, J.; Bennett, D.; Weigel, A. V.; Walther, T. C.; Farese, R. V.; van Engelenburg, S. B.; Mellman, I.; Solimena, M.; Hess, H. F.
10.1101/2020.11.13.382457 — cell biology — Posted on 2020-11-14
2256 The Nuclear Pore Complex consists of two independent scaffolds
Regmi, S. G.; Lee, H.; Kaufhold, R.; Fichtman, B.; Chen, S.; Aksenova, V.; Turcotte, E.; Harel, A.; Arnaoutov, A.; Dasso, M.
10.1101/2020.11.13.381947 — cell biology — Posted on 2020-11-14
2257 Patient-specific iPSCs carrying an SFTPC mutation reveal the intrinsic alveolar epithelial dysfunction at the inception of interstitial lung disease
Alysandratos, K.-D.; Russo, S. J.; Petcherski, A.; Taddeo, E. P.; Acin-Perez, R.; Villacorta-Martin, C.; Jean, J.-C.; Mulugeta, S.; Blum, B. C.; Hekman, R. M.; Vedaie, M.; Kook, S.; Wambach, J. A.; Cole, F. S.; Hamvas, A.; Emili, A.; Guttentag, S. H.; Shirihai, O. S.; Beers, M. F.; Kotton, D. N.
10.1101/2020.11.13.382390 — cell biology — Posted on 2020-11-14
2260 Decoding and blocking the bacterial lipid flippase MprF yields a novel anti-virulence strategy
Slavetinsky, C. J.; Hauser, J. N.; Gekeler, C.; Slavetinsky, J.; Geyer, A.; Kraus, A.; Heilingbrunner, D.; Wagner, S.; Tesar, M.; Weidenmaier, C.; Krismer, B.; Kuhn, S.; Ernst, C. M.; Peschel, A.
10.1101/2020.11.12.379776 — microbiology — Posted on 2020-11-14
2261 Decoding music-evoked emotions in the auditory and motor cortex
Putkinen, V.; Nazari-Farsani, S.; Seppala, K.; Karjalainen, T.; Sun, L.; Karlsson, H. K.; Hudson, M.; Heikkila, T. T.; Hirvonen, J.; Nummenmaa, L.
10.1101/2020.05.24.101667 — neuroscience — Posted on 2020-11-14
2265 Epidermal stem cell compartment remains unaffected through aging in naked mole-rats.
Savina, A.; Jaffredo, T.; Saldmann, F.; Faulkes, C. G.; Moguelet, P.; Leroy, C.; Del Marmol, D.; Codogno, P.; Foucher, L.; Viltard, M.; Friedlander, G.; Aractingi, S.; Fontaine, R. H.
10.1101/2020.11.13.381061 — cell biology — Posted on 2020-11-14
2267 Properdin oligomers adopt rigid extended conformations supporting function
Pedersen, D. V.; Pedersen, M. N.; Mazarakis, S. M.; Wang, Y.; Lindorff-Larsen, K.; Arleth, L.; Andersen, G. R.
10.1101/2020.11.13.381772 — immunology — Posted on 2020-11-14
2268 Schizophrenia and autism-associated mutations and disrupted m6A signal by YTHDF1 cause defects in microtubule function and neurodevelopment
Roy, R.; Li, X.; Hou, S.; Fujiwara, Y.; Sukegawa, M.; Hong, W.-T.; Oomoto, I.; Ito, H.; Joshi, K.; Fan, R.; Nagata, K.-i.; Lai, K.-o.; Wang, D. O.
10.1101/2020.11.14.382556 — neuroscience — Posted on 2020-11-14
2270 Nutritional status and fecundity are synchronised by muscular exopheresis
Turek, M.; Piechota, M.; Banasiak, K.; Shanmugam, N.; Macias, M.; Sliwinska, M. A.; Niklewicz, M.; Kowalski, K.; Nowak, N.; Chacinska, A.; Pokrzywa, W.
10.1101/2020.06.17.157230 — physiology — Posted on 2020-11-14
2273 Global gene expression analysis of Streptococcus agalactiae at exponential growth phase
Silvestre, I.; Borges, V.; Duarte, S.; Nunes, A.; Sobral, R.; Vieira, L.; Gomes, J. P.; Borrego, M. J.
10.1101/2020.11.13.381939 — genomics — Posted on 2020-11-14
2276 EVALUATION OF ANTIMICROBIAL AND ANTIPROLIFERATIVE ACTIVITIES OF ACTINOBACTERIA ISOLATED FROM THE SALINE LAGOONS OF NORTHWEST PERU
Flores Clavo, R.; Ruiz Quinones, N.; Tasca Hernandez, A.; Tasca Gois Ruiz, A. L.; de Oliveira Braga, L. E.; Arce Gil, Z. L.; Serquen Lopez, L. M.; Henrique Costa, J.; Pacheco Fill, T.; Jose Salvador, M.; Fantinatti Garboggini, F.
10.1101/2020.10.07.329441 — molecular biology — Posted on 2020-11-14
2278 Functional pathway redundancy in the metabolism of plant-derived phenolics by Novosphingobium aromaticivorans
Perez, J. M.; Kontur, W. S.; Gehl, C.; Gille, D. M.; Ma, Y.; Niles, A. V.; Umana, G.; Donohue, T. J.; Noguera, D. R.
10.1101/2020.11.13.382549 — microbiology — Posted on 2020-11-14
2279 The two formyl peptide receptors differently regulate GPR84-mediated neutrophil NADPH-oxidase activity
Martensson, J.; Sundqvist, M.; Manandhar, A.; Ieremias, L.; Linjie, L.; Ulven, T.; Xie, X.; Bjorkman, L.; Forsman, H.
10.1101/2020.11.13.381582 — immunology — Posted on 2020-11-14
2281 Variations of intracellular density during the cell cycle arises from tip-growth regulation in fission yeast
Odermatt, P. D.; Miettinen, T. P.; Kang, J. H.; Bostan, E.; Manalis, S.; Huang, K. C.; Chang, F.
10.1101/2020.10.21.349696 — biophysics — Posted on 2020-11-14
2284 Metabolically-Driven Maturation of hiPSC-Cell Derived Heart-on-a-Chip
Huebsch, N.; Charrez, B.; Siemons, B.; Boggess, S. C.; Wall, S.; Neiman, G.; Charwat, V.; Jaeger, K.; Montiel, F. L. T.; Jeffreys, N. C.; Deveshwar, N.; Edwards, A.; Serrano, J.; Snuderl, M.; Stahl, A.; Tveito, A.; Miller, E. W.; Healy, K. E.
10.1101/485169 — bioengineering — Posted on 2020-11-14
2286 Skewed X inactivation in genetically diverse mice is associated with recurrent copy number changes at the Xce locus
Sun, K. Y.; Oreper, D. G.; Schoenrock, S. A.; McMullan, R.; Giusti-Rodriguez, P.; Zhabotynsky, V.; Miller, D. R.; Tarantino, L. M.; Pardo-Manuel de Villena, F.; Valdar, W.
10.1101/2020.11.13.380535 — genetics — Posted on 2020-11-14
2290 Smad3 Regulates Smooth Muscle Cell Fate and Governs Adverse Remodeling and Calcification of Atherosclerotic Plaque
Cheng, P.; Wirka, r.; Kim, J.; Nguyen, T.; Kundu, R.; Zhao, q.; Pedroza, A.; Nagao, M.; Iyer, D.; Fischbein, M.; Quertermous, T.
10.1101/2020.09.15.299131 — cell biology — Posted on 2020-11-14
2291 Differences in Activation of Intracellular Signalling in Primary Human Retinal Endothelial Cells Between Isoforms of VEGFA-165.
Dailey, W.; Schunemann, R.; Yang, F.; Moore, M.; Knapp, A.; Chen, P.; Deshpande, M.; Metcalf, B.; Tompkins, Q.; Guzman, A. E.; Felisky, J.; Mitton, K. P.
10.1101/2019.12.12.871947 — cell biology — Posted on 2020-11-14
2292 High Throughput RNA Sequencing of Germ- Free Mouse Retina Reveals Metabolic Pathways Involved in the Gut-Retina Axis
Nadeem, U.; Xie, B.; Movahedan, A.; D'Souza, M.; Barba, H.; Deng, N.; Leonne, V.; Chang, E. B.; Sulakhe, D.; Skondra, D.
10.1101/2020.10.01.318949 — molecular biology — Posted on 2020-11-14
2293 A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of infective endocarditis
Gaytan, M. O.; Singh, A. K.; Woodiga, S. A.; Patel, S. A.; An, S.-S.; Vera Ponce de Leon, A.; McGrath, S.; Miller, A. R.; Bush, J. M.; van der Linden, M.; Magrini, V.; Wilson, R. K.; Kitten, T.; King, S. J.
10.1101/2020.07.17.206995 — microbiology — Posted on 2020-11-14
2297 Hierarchical motor adaptations negotiate failures during force field learning
Ikegami, T.; Ganesh, G.; Gibo, T. L.; Yoshioka, T.; Osu, R.; Kawato, M.
10.1101/2020.07.16.207084 — neuroscience — Posted on 2020-11-14
2302 Adaptation of pancreatic cancer cells to nutrient deprivation is reversible and requires glutamine synthetase stabilization by mTORC1
Tsai, P.-Y.; Lee, M.-S.; Jadhav, U.; Naqvi, I.; Madha, S.; Adler, A.; Mistry, M.; Naumenko, S.; Lewis, C. A.; Hitchcock, D. S.; Roberts, F. R.; DelNero, P.; Hank, T.; Honselmann, K. C.; Morales Oyarvide, V.; Mino-Kenudson, M.; Clish, C. B.; Shivdasani, R. A.; Kalaany, N. Y.
10.1101/2020.02.16.951681 — cancer biology — Posted on 2020-11-14
2311 Lateral and longitudinal fish eDNA distribution in dynamic riverine habitats
Thalinger, B.; Kirschner, D.; Putz, Y.; Moritz, C.; Schwarzenberger, R.; Wanzenboeck, J.; Traugott, M.
10.1101/2020.05.28.120147 — ecology — Posted on 2020-11-14
2312 The Nab2 RNA binding protein promotes sex-specific splicing of Sex lethal in Drosophila neuronal tissue
Jalloh, B.; Rounds, J. C.; Brown, B.; Kremsky, I.; Banerjee, A.; Morton, D. J.; Bienkowski, R.; Fasken, M. B.; Corbett, A. H.; Moberg, K. H.
10.1101/2020.11.13.382168 — developmental biology — Posted on 2020-11-14
2314 Lipid-specific protein oligomerization is regulated by two interfaces in Marburg virus matrix protein VP40
Amiar, S.; Husby, M. L.; Wijesinghe, K. J.; Angel, S.; Bhattarai, N.; Gerstman, B. S.; Chapagain, P. P.; Li, S.; Stahelin, R. V.
10.1101/2020.11.13.381350 — microbiology — Posted on 2020-11-14
2315 Plasmodium falciparum malaria drives epigenetic reprogramming of human monocytes toward a regulatory phenotype
Guha, R.; Mathioudaki, A.; Doumbo, S.; Doumtabe, D.; Skinner, J.; Arora, G.; Siddiqui, S.; Li, S.; Kayentao, K.; Ongoiba, A.; Zaugg, J. B.; Traore, B.; Crompton, P. D.
10.1101/2020.10.21.346197 — immunology — Posted on 2020-11-14
2316 Antisense oligonucleotide therapy for KCNT1 encephalopathy
Burbano, L. E.; Li, M.; Jancovsky, N.; Jafar-Nejad, P.; Richards, K.; Sedo, A.; Soriano, A.; Rollo, B.; Jia, L.; Gazina, E.; Piltz, S.; Adikusuma, F.; Thomas, P. Q.; Rigo, F.; Reid, C. A.; Maljevic, S.; Petrou, S.
10.1101/2020.11.12.379164 — neuroscience — Posted on 2020-11-14
2319 A metabolic coincidence mechanism controls winter photoperiodism in plants
Liu, W.; Feke, A.; Leung, C. C.; Tarte, D.; Yuan, W.; Vanderwall, M.; Sager, G. C.; Wu, X.; Schear, A.; Clark, D.; Thines, B. C.; Gendron, J.
10.1101/2020.11.13.381426 — plant biology — Posted on 2020-11-14
2322 Therapeutic inhibition of acid sensing ion channel 1a recovers heart function after ischemia-reperfusion injury
Redd, M.; Scheuer, S.; Saez, N.; Yoshikawa, Y.; Chiu, H.; Gao, L.; Hicks, M.; Villanueva, J.; Cuellar-Partida, G.; Peart, J.; See Hoe, L.; Chen, X.; Sun, Y.; Suen, J.; Hatch, R.; Rollo, B.; Alzubaidi, M.; Maljevic, S.; Qaiffe-Ryan, G. A.; Hudson, J. E.; Porrello, E.; White, M.; Cordwell, S.; Fraser, J.; Petrou, S.; Reichelt, M.; Thomas, W.; King, G.; MacDonald, P.; Palpant, N.
10.1101/869826 — physiology — Posted on 2020-11-14
2323 The solution structures of higher-order human telomere G-quadruplex multimers
Monsen, R. C.; Chakravarthy, S.; Dean, W. L.; Chaires, J. B.; Trent, J. O.
10.1101/2020.11.13.382036 — biophysics — Posted on 2020-11-14
2326 BAP1 constrains pervasive H2AK119ub1 to control the transcriptional potential of the genome
Fursova, N. A.; Turberfield, A. H.; Blackledge, N. P.; Findlater, E. L.; Lastuvkova, A.; Huseyin, M. K.; Dobrinic, P.; Klose, R. J.
10.1101/2020.11.13.381251 — molecular biology — Posted on 2020-11-14
2327 Common virulence gene expression in naive and severe malaria cases
Wichers, J. S.; Tonkin-Hill, G.; Thye, T.; Krumkamp, R.; Strauss, J.; von Thien, H.; Kreuels, B.; Scholz, J. A. M.; Hansson, H. H.; Jensen, R. W.; Turner, L.; Lorenz, F.-R.; Schoellhorn, A.; Bruchhaus, I.; Tannich, E.; Fendel, R.; Otto, T. D.; Lavstsen, T.; Gilberger, T. W.; Duffy, M. F.; Bachmann, A.
10.1101/2020.11.13.381137 — molecular biology — Posted on 2020-11-14
2329 HIV-1 uncoating by release of viral cDNA from capsid-like structures in the nucleus of infected cells.
Müller, T. G.; Zila, V.; Peters, K.; Schifferdecker, S.; Stanic, M.; Lucic, B.; Laketa, V.; Lusic, M.; Müller, B.; Kräusslich, H.-G.
10.1101/2020.11.13.380030 — microbiology — Posted on 2020-11-14
2330 Cellular and immunological mechanisms mediate reservoir host specialization by genotypically variable microparasites
Lin, Y.-P.; Tufts, D. M.; Dupuis, A. P.; Combs, M.; Marcinkiewicz, A. L.; Hirsbrunner, A. D.; Diaz, A. J.; Stout, J. L.; Blom, A. M.; Strle, K.; Davis, A. D.; Kramer, L. D.; Diuk-Wasser, M. A.
10.1101/2020.11.13.380550 — microbiology — Posted on 2020-11-14
2332 ILRUN downregulates ACE2 expression and blocks infection of human cells by SARS-CoV-2
Tribolet, L.; Alexander, M.; Brice, A.; Jansen Van Vuren, P.; Rootes, C.; Mara, K.; McDonald, M.; Bruce, K.; Gough, T.; Shi, S.; Cowled, C.; Bean, A.; Stewart, C. R.
10.1101/2020.11.13.381343 — cell biology — Posted on 2020-11-13
2335 A Whole Virion Vaccine for COVID-19 Produced Via a Novel Inactivation Method: Results from Animal Challenge Model Studies
Ragan, I. K.; Hartson, L. M.; Dutt, T. S.; Obregon-Henao, A.; Maison, R. M.; Gordy, P.; Fox, A.; Karger, B. R.; Cross, S. T.; Kapuscinski, M. L.; Cooper, S. K.; Podell, B. K.; Stenglein, M. D.; Bowen, R. A.; Henao-Tamayo, M.; Goodrich, R.
10.1101/2020.11.13.381335 — immunology — Posted on 2020-11-13
2336 A Theory for the Emergence of Neocortical Network Architecture
Udvary, D.; Harth, P.; Macke, J. H.; Hege, H.-C.; de Kock, C. P. J.; Sakmann, B.; Oberlaender, M.
10.1101/2020.11.13.381087 — neuroscience — Posted on 2020-11-13
2344 Quantification of Brucella abortus population structure in a natural host
Fiebig, A.; Vrentas, C. E.; Le, T. M.; Huebner, M.; Boggiatto, P. M.; Olsen, S. C.; Crosson, S.
10.1101/2020.11.12.380766 — microbiology — Posted on 2020-11-13
2345 StrongestPath: a Cytoscape application for protein-protein interaction analysis
Mousavian, Z.; Khodabandeh, M.; Sharifi-Zarchi, A.; Nadafian, A.; Mahmoudi, A.
10.1101/2020.11.12.380600 — systems biology — Posted on 2020-11-13
2346 SeqPIP-2020: Sequence based Protein InteractionPrediction Contest
Halder, A. K.; Mollah, A. F.; Chatterjee, P.; Kole, D. K.; Basu, S.; Plewczynski, D.
10.1101/2020.11.12.380774 — bioinformatics — Posted on 2020-11-13
2349 Defining the ultrastructure of the hematopoietic stem cell niche by correlative light and electron microscopy
Agarwala, S.; Kim, K.-Y.; Phan, S.; Ju, S.; Kong, Y. E.; Castillon, G. A.; Bushong, E. A.; Ellisman, M. H.; Tamplin, O. J.
10.1101/2020.11.12.380790 — developmental biology — Posted on 2020-11-13
2350 Flexible fitting of PROTAC concentration-response curves with Gaussian Processes
Semenova, E.; Guerriero, M. L.; Zhang, B.; Hock, A.; Hopcroft, P.; Kadamur, G.; Afzal, A. M.; Lazic, S. E.
10.1101/2020.11.13.379883 — cell biology — Posted on 2020-11-13
2353 Accumbens D2-MSN hyperactivity drives behavioral supersensitivity
Kruyer, A.; Parilla-Carerro, J.; Powell, C.; Brandt, L.; Gutwinski, S.; Angelis, A.; Chalhoub, R.; Amato, D.
10.1101/2020.11.12.380667 — neuroscience — Posted on 2020-11-13
2356 Applications of genetic-epigenetic tissue mapping for plasma DNA in prenatal testing, transplantation and oncology
Gai, W.; Zhou, Z.; Agbor-Enoh, S.; Fan, X.; Lian, S.; Jiang, P.; Cheng, S. H.; Wong, J.; Chan, S. L.; Jang, M. K.; Yang, Y.; Liang, R. H. S.; Chan, W. K.; Ma, E. S. K.; Leung, T. Y.; Chiu, R. W. K.; Valantine, H.; Chan, K. C. A.; Lo, Y. M. D.
10.1101/2020.11.13.381178 — physiology — Posted on 2020-11-13
2360 Automatic wound detection and size estimation using deep learning algorithms
Carrion, H.; Jafari, M.; Bagood, M. D.; Yang, H.-y.; Isseroff, R. R.; Gomez, M.
10.1101/2020.11.13.275917 — bioinformatics — Posted on 2020-11-13
2363 Electrical Stimulation Of The Cervical Dorsal Roots Enables Functional Arm And Hand Movements In Monkeys With Cervical Spinal Cord Injury
Barra, B.; Conti, S.; Perich, M. G.; Zhuang, K.; Schiavone, G.; Fallegger, F.; Galan, K.; James, N.; Barraud, Q.; Delacombaz, M.; Kaeser, M.; Rouiller, E. M.; Milekovic, T.; Lacour, S.; Bloch, J.; Courtine, G.; Capogrosso, M.
10.1101/2020.11.13.379750 — bioengineering — Posted on 2020-11-13
2364 A model of resource partitioning between foraging bees
Dubois, T.; Pasquaretta, C.; Barron, A.; Gautrais, J.; Lihoreau, M.
10.1101/2020.11.13.381012 — animal behavior and cognition — Posted on 2020-11-13
2369 Genetic variation at the Cyp6m2 putative insecticide resistance locus in Anopheles gambiae and Anopheles coluzzii
Wagah, M. G.; Korlevic, P.; Clarkson, C.; Miles, A.; The Anopheles gambiae 1000 Genomes Consortium, ; Lawniczak, M. K. N.; Makunin, A.
10.1101/2020.11.12.378943 — genetics — Posted on 2020-11-13
2370 Polygenic transcriptome risk scores improve portability of polygenic risk scores across ancestries
Liang, Y.; Pividori, M.; Manichaikul, A.; Palmer, A. A.; Cox, N. J.; Wheeler, H. E.; Im, H. K.
10.1101/2020.11.12.373647 — genetics — Posted on 2020-11-13
2371 Genome-wide association studies reveal the complex genetic architecture of DMI fungicide resistance in Cercospora beticola
Spanner, R.; Taliadoros, D.; Richards, J.; Rivera-Varas, V.; Neubauer, J.; Natwick, M.; Hamilton, O.; Vaghefi, N.; Pethybridge, S.; Secor, G. A.; Friesen, T. L.; Stukenbrock, E. H.; Bolton, M. D.
10.1101/2020.11.12.379818 — evolutionary biology — Posted on 2020-11-13
2374 Ten-year projection of white-nose syndrome disease dynamics at the southern leading-edge of infection in North America
Meierhofer, M. B.; Lilley, T. M.; Ruokolainen, L.; Johnson, J. S.; Parratt, S. R.; Morrison, M. L.; Pierce, B. L.; Evans, J. W.; Anttila, J.
10.1101/2020.11.12.379271 — ecology — Posted on 2020-11-13
2376 Developmental Single-cell transcriptomics in the Lytechinus variegatus 1 Sea Urchin Embryo
Massri, A. J.; Greenstreet, L.; Afanassiev, A.; Escobar, A. B.; Wray, G. M.; Schiebinger, G.; McClay, D. R.
10.1101/2020.11.12.380675 — developmental biology — Posted on 2020-11-13
2377 Contemplative mental training reduces hair glucocorticoid levels in a randomized clinical trial
Puhlmann, L.; Vrticka, P.; Linz, R.; Stalder, T.; Kirschbaum, C.; Engert, V.; Singer, T.
10.1101/2020.11.13.381038 — molecular biology — Posted on 2020-11-13
2378 Substrate-induced modulation of protein-protein interactions within human mitochondrial cytochrome P450-dependent system
Yablokov, E.; Sushko, T.; Kaluzhskiy, L.; Kavaleuski, A.; Mezentsev, Y.; Ershov, P.; Gilep, A.; Ivanov, A.; Strushkevich, N.
10.1101/2020.11.13.381095 — molecular biology — Posted on 2020-11-13
2379 Sex-specific lipid profiles in muscle of Atlantic salmon juveniles
House, A. H.; Primmer, C. R.; Debes, P. V.; Erkinaro, J.; Kakela, R.; Kurko, J.
10.1101/2020.11.13.379321 — molecular biology — Posted on 2020-11-13
2381 Rhipicephalus microplus and its vector-borne haemoparasites in Guinea: further species expansion in West Africa
Makenov, M. T.; Toure, A. H.; Korneev, M. G.; Sacko, N.; Porshakov, A. M.; Yakovlev, S. A.; Radyuk, E. V.; Zakharov, K. S.; Shipovalov, A. V.; Boumbaly, S.; Zhurenkova, O. B.; Grigoreva, Y. E.; Morozkin, E. S.; Fyodorova, M. V.; Karan, L. S.; Boiro, M. Y.
10.1101/2020.11.12.376426 — zoology — Posted on 2020-11-13
2382 Micromanipulation of amyloplasts with optical tweezers in Arabidopsis stems
Abe, Y.; Meguriya, K.; Matsuzaki, T.; Sugiyama, T.; Y. Yoshikawa, H.; Terao Morita, M.; Toyota, M.
10.1101/2020.11.12.379289 — plant biology — Posted on 2020-11-13
2386 Large-scale monitoring of resistance to coumaphos, amitraz and pyrethroids in Varroa destructor
Hernandez-Rodriguez, C. S.; Calatayud, F.; Mahiques, M. J.; Mompo, A.; Segura, I.; Simo, E.; Gonzalez-Cabrera, J.
10.1101/2020.11.12.378190 — pharmacology and toxicology — Posted on 2020-11-13
2388 Characterization of LC-MS based urine metabolomics in healthy subjects across the life span
Sun, W.; Liu, X.; Shi, Q.; Sun, H.; Li, J.; Tang, X.; Guo, Z.; Liu, Y.; Ma, J.; Ren, N.; Jin, F.; He, C.; Song, W.
10.1101/2020.11.12.379131 — biochemistry — Posted on 2020-11-13
2391 Molecular basis for a germline-biased neutralizing antibody response to SARS-CoV-2
Clark, S. A.; Clark, L. E.; Pan, J.; Coscia, A.; McKay, L. G. A.; Shankar, S.; Johnson, R. I.; Griffiths, A.; Abraham, J.
10.1101/2020.11.13.381533 — microbiology — Posted on 2020-11-13
2393 In Vitro Activity of Itraconazole Against SARS-CoV-2
Van Damme, E.; De Meyer, S.; Bojkova, D.; Ciesek, S.; Cinatl, J.; De Jonghe, S.; Jochmans, D.; Leyssen, P.; Buyck, C.; Neyts, J.; Van Loock, M.
10.1101/2020.11.13.381194 — pharmacology and toxicology — Posted on 2020-11-13
2394 Ongoing Global and Regional Adaptive Evolution of SARS-CoV-2
Rochman, N. D.; Wolf, Y. I.; Faure, G.; Zhang, F.; Koonin, E. V.
10.1101/2020.10.12.336644 — microbiology — Posted on 2020-11-13
2395 The effect of temperature and humidity on the stability of SARS-CoV-2 and other enveloped viruses
Morris, D. H.; Yinda, K. C. H.; Gamble, A.; Rossine, F. W.; Huang, Q.; Bushmaker, T.; Fischer, R. J.; Matson, M. J.; van Doremalen, N.; Vikesland, P. J.; Marr, L. C.; Munster, V.; Lloyd-Smith, J. O.
10.1101/2020.10.16.341883 — microbiology — Posted on 2020-11-13
2396 Synergism of TNF-α and IFN-γ triggers inflammatory cell death, tissue damage, and mortality in SARS-CoV-2 infection and cytokine shock syndromes
Karki, R.; Sharma, B. R.; Tuladhar, S.; Williams, E. P.; Zalduondo, L.; Samir, P.; Zheng, M.; Sundaram, B.; Banoth, B.; Malireddi, R. K. S.; Schreiner, P.; Neale, G.; Vogel, P.; Webby, R.; Jonsson, C. B.; Kanneganti, T.-D.
10.1101/2020.10.29.361048 — immunology — Posted on 2020-11-13
2400 Homemade Bread: Repurposing an Ancient Technology for Low Cost in vitro Tissue Engineering
Holmes, J. T.; Jaberansari, Z.; Collins, W.; Leblanc Latour, M.; Modulevsky, D. J.; Pelling, A.
10.1101/2020.11.13.353698 — bioengineering — Posted on 2020-11-13
2401 Polycomb Repressive Complex 2-controlled Essrg regulates intestinal Microfold cell differentiation.
George, J. J.; Oittinen, M.; Diaz, L. M.; Zapilko, V.; Iqbal, S.; Rintakangas, T.; Martins, F. T. A.; Niskanen, H.; Katajisto, P.; Kaikkonen, M. U.; Viiri, K.
10.1101/2020.11.13.379610 — molecular biology — Posted on 2020-11-13
2402 Extracellular signal-regulated kinase mediates chromatin rewiring and lineage transformation in lung cancer
Inoue, Y.; Nikolic, A.; Farnsworth, D.; Liu, A.; Ladanyi, M.; Somwar, R.; Gallo, M.; Lockwood, W.
10.1101/2020.11.12.368522 — cancer biology — Posted on 2020-11-13
2403 Streptococcus suis induces expression of cyclooxygenase-2 in porcine lung tissue
Dresen, M.; Schenk, J.; Berhanu Weldearegay, Y.; Vötsch, D.; Baumgärtner, W.; Valentin-Weigand, P.; Nerlich, A.
10.1101/2020.11.10.371575 — microbiology — Posted on 2020-11-13
2404 Genomic basis of parallel adaptation varies with divergence in Arabidopsis and its relatives
Bohutinska, M.; Vlcek, J.; Yair, S.; Leanen, B.; Konecna, V.; Fracassetti, M.; Slotte, T.; Kolar, F.
10.1101/2020.03.24.005397 — evolutionary biology — Posted on 2020-11-13
2405 Intraspecific diversity loss in a predator species alters prey community structure and ecosystem functions
Raffard, A.; Cucherousset, J.; Montoya, J. M.; Richard, M.; Acoca-Pidolle, S.; Poesy, C.; Garreau, A.; Santoul, F.; Blanchet, S.
10.1101/2020.06.10.144337 — ecology — Posted on 2020-11-13
2406 Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI
Santini, T.; Koo, M.; Farhat, N.; Campos, V. P.; Alkhateeb, S.; Vieira, M. A. C.; Butters, M. A.; Rosano, C.; Aizenstein, H. J.; Mettenburg, J.; Novelli, E. M.; Ibrahim, T. S.
10.1101/2020.11.10.377564 — neuroscience — Posted on 2020-11-13
2411 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-13
2412 Genetic landscape of recessive diseases in the Vietnamese population from large-scale clinical exome sequencing
Tran, N. H.; Nguyen Thi, T.-H.; Tang, H.-S.; Hoang, L.-P.; Nguyen, T.-H. L.; Tran, N.-T.; Trinh, T.-H. N.; Nguyen, V. T.; Nguyen, B.-H. H.; Nguyen, H. T.; Doan, L. P.; Phan, N.-M.; Nguyen, K.-H. T.; Nguyen, H.-D. L.; Quach, M.-T. T.; Nguyen, T.-P. T.; Tran, V. U.; Tran, D.-V.; Nguyen, Q.-T. T.; Do, T.-T. T.; Lam, N. V.; Cao Thi Ngoc, P.; Truong, D. K.; Nguyen, H.-N.; Phan, M.-D.; Giang, H.
10.1101/2020.10.27.358358 — genetics — Posted on 2020-11-13
2414 A Multiplexed Bacterial Two-Hybrid for Rapid Characterization of Protein-Protein Interactions and Iterative Protein Design
Boldridge, W. C.; Ljubetic, A.; Kim, H.; Lubock, N.; Szilagyi, D.; Lee, J.; Brodnik, A.; Jerala, R.; Kosuri, S.
10.1101/2020.11.12.377184 — molecular biology — Posted on 2020-11-13
2416 Unique Evolution of Antiviral Tetherin in Bats
Hayward, J. A.; Tachedjian, M.; Johnson, A.; Irving, A. T.; Gordon, T. B.; Cui, J.; Nicolas, A.; Smith, I.; Boyd, V.; Marsh, G. A.; Baker, M. L.; Wang, L.-F.; Tachedjian, G.
10.1101/2020.04.08.031203 — evolutionary biology — Posted on 2020-11-12
2417 High-throughput generation and phenotypic characterization of zebrafish CRISPR mutants of DNA repair genes
Shin, U.; Nakhro, K.; Oh, C.-K.; Carrington, B.; Song, H.; Varshney, G. K.; Kim, Y.; Song, H.; Jeon, S.; Robbins, G.; Kim, S.; Yoon, S.; Choi, Y.; Park, S.; Kim, Y. J.; Burgess, S. M.; Kang, S.; Sood, R.; Lee, Y.; Myung, K.
10.1101/2020.10.04.325621 — developmental biology — Posted on 2020-11-12
2420 Maternal RND3/RhoE deficiency impairs placental mitochondrial function in preeclampsia by modulating PPARγ-UCP2 cascade
Huang, L.; Ma, Y.; Chen, L.; Chang, J.; Zhong, M.; Wang, Z.; Sun, Y.; Chen, X.; Sun, F.; Xiao, L.; Chen, J.; Lai, Y.; Yan, C.; Yue, X.
10.1101/2020.06.22.164921 — pathology — Posted on 2020-11-12
2422 Morphology and immunhistchemical characteristics of the otic ganglion in chinchilla (Chinchila laniger Molina).
Sienkiewicz, W.; Kuchinka, J.; Dudek, A.; Nowak, E.; Kaleczyc, J.; Radzimirska, M.; Szczurkowski, A.
10.1101/2020.11.12.379503 — neuroscience — Posted on 2020-11-12
2423 Deleting Mecp2 from the entire cerebellum rather than its neuronal subtypes causes a delay in motor learning in mice
Achilly, N. P.; He, L.; Kim, O. A.; Ohmae, S.; Wojaczynski, G. J.; Lin, T.; Sillitoe, R. V.; Medina, J. F.; Zoghbi, H. Y.
10.1101/2020.11.12.380162 — neuroscience — Posted on 2020-11-12
2430 Effects of additional load at different heights on gait initiation: a statistical parametric mapping of center of pressure and center of mass behavior
Vieira, M. F.; Rodrigues, F. B.; de Oliveira Assis, A.; de Mendonca Mesquita, E.; Lemes, T. S.; De Villa, G. A. G.; Baptista, R. R.; de Oliveira Andrade, A.; Lobo da Costa, P. H.
10.1101/2020.11.12.380261 — bioengineering — Posted on 2020-11-12
2431 ORF3a mediated-incomplete autophagy facilitates SARS-CoV-2 replication
Qu, Y.; Wang, X.; Zhu, Y.; Wang, Y.; Yang, X.; Hu, G.; Liu, C.; Li, J.; Ren, S.; Xiao, Z.; Liu, Z.; Wang, W.; Li, P.; Zhang, R.; Liang, Q.
10.1101/2020.11.12.380709 — microbiology — Posted on 2020-11-12
2432 A practical PPE decontamination method using warm air and ambient humidity
Kwiek, J. J.; Pickett, C. R.; Flanigan, C. A.; Lee, M. V.; Saif, L. J.; Jahnes, J.; Blonder, G.
10.1101/2020.11.12.380196 — microbiology — Posted on 2020-11-12
2434 POINT Technology Illuminates The Processing Of Polymerase-Associated Intact Nascent Transcripts
Sousa-Luis, R.; Dujardin, G.; Zukher, I.; Kimura, H.; Carmo-Fonseca, M.; Proudfoot, N.; Nojima, T.
10.1101/2020.11.09.374108 — genomics — Posted on 2020-11-12
2436 A streamlined workflow for automated cryo focused ion beam milling
Tacke, S.; Erdmann, P.; Wang, Z.; Klumpe, S.; Grange, M.; Plitzko, J.; Raunser, S.
10.1101/2020.02.24.963033 — molecular biology — Posted on 2020-11-12
2438 Ribosome quality control activity potentiates vaccinia virus protein synthesis during infection
Sundaramoorthy, E.; Ryan, A. P.; Fulzele, A.; Leonard, M.; Daugherty, M. D.; Bennett, E. J.
10.1101/2020.11.12.380634 — molecular biology — Posted on 2020-11-12
2439 The chemotherapeutic drug methotrexate selects for antibiotic resistance
Guthmundsdottir, J. S.; Fredheim, E. G. A.; Koumans, C. I. M.; Hegstad, J.; Tang, P.-C.; Andersson, D. I.; Samuelsen, O.; Johnsen, P. J.
10.1101/2020.11.12.378059 — microbiology — Posted on 2020-11-12
2447 Structure and lipid dynamics in the A. baumannii maintenance of lipid asymmetry (MLA) inner membrane complex
Mann, D.; Fan, J.; Farrell, D.; Somboon, K.; Muenks, A.; Tzokov, S.; Khalid, S.; DiMaio, F.; Miller, S.; Bergeron, J.
10.1101/2020.05.30.125013 — biochemistry — Posted on 2020-11-12
2451 Negative density-dependent parasitism in a group-living carnivore
Albery, G. F.; Newman, C.; Bright Ross, J. G.; MacDonald, D. W.; Bansal, S.; Buesching, C. D.
10.1101/2020.06.15.153726 — ecology — Posted on 2020-11-12
2452 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dillmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-12
2453 Mitochondrial profiling reveals dynamic, sex- and age-specific mitochondrial phenotypes in human immune cell subtypes
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2020-11-12
2455 Western Kenyan Anopheles gambiae s.s. showing intense permethrin resistance harbor distinct microbiota
Omoke, D.; Kipsum, M.; Otieno, S.; Esalimba, E.; Sheth, M.; Lenhart, A.; Njeru, E. M.; Ochomo, E.; Dada, N.
10.1101/2020.11.12.378760 — molecular biology — Posted on 2020-11-12
2456 Morc3 silences endogenous retroviruses by enabling Daxx-mediated H3.3 incorporation
Groh, S.; Milton, A. V.; Marinelli, L.; Sickinger, C. V.; Bollig, H.; de Almeida, G. P.; Schmidt, A.; Forne, I.; Imhof, A.; Schotta, G.
10.1101/2020.11.12.380204 — molecular biology — Posted on 2020-11-12
2457 Structure of the molecular bushing of the bacterial flagellar motor
Yamaguchi, T.; Makino, F.; Miyata, T.; Minamino, T.; Kato, T.; Namba, K.
10.1101/2020.11.12.379347 — molecular biology — Posted on 2020-11-12
2458 New Insights and Enhanced Human Norovirus Cultivation in Human Intestinal Enteroids
Ettayebi, K.; Tenge, V. R.; Cortes-Penfield, N. W.; Crawford, S. E.; Neill, F. H.; Zeng, X.-L.; Yu, X.; Ayyar, V. B.; Burrin, D.; Ramani, S.; Atmar, R. L.; Estes, M. K.
10.1101/2020.11.12.380022 — microbiology — Posted on 2020-11-12
2459 Goblet Cell Hyperplasia Increases SARS-CoV-2 Infection in COPD
Mehedi, M.; Osan, J. K.; Talukdar, S. N.; Feldmann, F.; DeMontigny, B. A.; Jerome, K.; Bailey, K. L.; Feldmann, H.
10.1101/2020.11.11.379099 — microbiology — Posted on 2020-11-12
2461 High-fat diet-induced activation of SGK1 promotes Alzheimer's disease-associated tau pathology
Elahi, M.; Motoi, Y.; Shimonaka, S.; Ishida, Y.; Hioki, H.; Takanashi, M.; Ishiguro, K.; Imai, Y.; Hattori, N.
10.1101/2020.05.14.095471 — neuroscience — Posted on 2020-11-12
2463 Single-cell RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates and humans
Bakken, T. E.; van Velthoven, C. T. J.; Menon, V.; Hodge, R. D.; Yao, Z.; Nguyen, T. N.; Graybuck, L. T.; Horwitz, G. D.; Bertagnolli, D.; Goldy, J.; Garren, E.; Parry, S.; Casper, T.; Shehata, S. I.; Barkan, E. R.; Szafer, A.; Levi, B. P.; Dee, N.; Smith, K. A.; Sunkin, S. M.; Bernard, A.; Phillips, J. W.; Hawrylycz, M.; Koch, C.; Murphy, G.; Lein, E.; Zeng, H.; Tasic, B.
10.1101/2020.11.05.367482 — neuroscience — Posted on 2020-11-12
2465 Massive X-ray screening reveals two allosteric drug binding sites of SARS-CoV-2 main protease
Guenther, S.; Reinke, P. Y. A.; Fernandez-Garcia, Y.; Lieske, J.; Lane, T. J.; Ginn, H.; Koua, F.; Ehrt, C.; Ewert, W.; Oberthuer, D.; Yefanov, O.; Meier, S.; Lorenzen, K.; Krichel, B.; Kopicki, J.; Gelisio, L.; Brehm, W.; Dunkel, I.; Seychell, B.; Gieseler, H.; Norton-Baker, B.; Escudero-Perez, B.; Domaracky, M.; Saouane, S.; Tolstikova, A.; White, T.; Haenle, A.; Groessler, M.; Fleckenstein, H.; Trost, F.; Galchenkova, M.; Gevorkov, Y.; Li, C.; Awel, S.; Peck, A.; Barthelmess, M.; Schluenzen, F.; Lourdu, X. P.; Werner, N.; Andaleeb, H.; Ullah, N.; Falke, S.; Srinivasan, V.; Franca, B.; Schwi
10.1101/2020.11.12.378422 — biophysics — Posted on 2020-11-12
2468 Nucleotide-resolution bacterial pan-genomics with reference graphs
Colquhoun, R. M.; Hall, M. B.; Lima, L.; Roberts, L. W.; Malone, K. M.; Hunt, M.; Letcher, B.; Hawkey, J.; George, S.; Pankhurst, L.; Iqbal, Z.
10.1101/2020.11.12.380378 — bioinformatics — Posted on 2020-11-12
2471 Fluorescent Antibody Multiplexing with Oligo-Based Combinatorial Labeling
McCarthy, M.; Anglin, C.; Pear, H.; Boleman, S.; Klaubert, S.; Birtwistle, M. R.
10.1101/2020.11.06.371906 — biochemistry — Posted on 2020-11-12
2473 Shapes and Genescapes: Mapping Multivariate Phenotype-Biological Process Associations for Craniofacial Shape
Aponte, J. D.; Katz, D. C.; Liu, W.; Andrade, F.; Roseman, C. C.; Murray, S. A.; Cheverud, J.; Marcucio, R.; Hallgrimsson, B.
10.1101/2020.11.12.378513 — genomics — Posted on 2020-11-12
2474 What's left in the tank? Identification of non-ascribed aquarium's coral collections with DNA barcodes as part of an integrated diagnostic approach
Colin, L.; Abed-Navandi, D.; A. Conde, D.; Craggs, J.; da Silva, R.; Janse, M.; Källström, B.; Pearce-Kelly, A.; yesson, C.
10.1101/2020.07.15.202739 — genetics — Posted on 2020-11-12
2475 Convergent Evolution of Pain-Inducing Defensive Venom Components in Spitting Cobras
Kazandjian, T. D.; Petras, D.; Robinson, S. D.; van Thiel, J.; Greene, H. W.; Arbuckle, K.; Barlow, A.; Carter, D. A.; Wouters, R. M.; Whiteley, G.; Wagstaff, S. C.; Arias, A. S.; Albulescu, L.-O.; von Plettenberg Laing, A.; Hall, C.; Heap, A.; Penrhyn-Lowe, S.; McCabe, C. V.; Ainsworth, S.; da Silva, R. R.; Dorrestein, P. C.; Richardson, M. K.; Gutierrez, J. M.; Calvete, J. J.; Harrison, R. A.; Vetter, I.; Undheim, E. A. B.; Wüster, W.; Casewell, N. R.
10.1101/2020.07.08.192443 — evolutionary biology — Posted on 2020-11-12
2476 Phylodynamic analysis of an emergent Mycobacterium bovis outbreak in an area with no previously known wildlife infections
Rossi, G.; Crispell, J.; Brough, T.; Lycett, S. J.; White, P. C. L.; Allen, A.; Ellis, R. J.; Gordon, S. V.; Harwood, R.; Palkopoulou, E.; Presho, E.; Skuce, R.; Smith, G. C.; Kao, R. R.
10.1101/2020.11.12.379297 — ecology — Posted on 2020-11-12
2478 Extended spectrum β-lactamase and carbapenemase genes are substantially and sequentially reduced during conveyance and treatment of urban sewage
Li, L.; Nesme, J.; Quintela-Baluja, M.; Balboa, S.; Hashsham, S.; Williams, M. R.; Yu, Z.; Sorensen, S. J.; Graham, D. W.; Romalde, J. L.; Dechesne, A.; Smets, B. F.
10.1101/2020.11.12.379032 — ecology — Posted on 2020-11-12
2480 SAM homeostasis is regulated by CFIm-mediated splicing of MAT2A
Scarborough, A. M.; Flaherty, J. N.; Hunter, O. V.; Liu, K.; Kumar, A.; Xing, C.; Tu, B. P.; Conrad, N. K.
10.1101/2020.11.12.380626 — molecular biology — Posted on 2020-11-12
2483 Structure of HIV-1 gp41 with its membrane anchors targeted by neutralizing antibodies
Caillat, C.; Guilligay, D.; Torralba, J.; Friedrich, N.; Nieva, J. L.; Trkola, A.; Chipot, C.; Dehez, F.; Weissenhorn, W.
10.1101/2020.11.12.379396 — microbiology — Posted on 2020-11-12
2484 Neuraminidase inhibitors rewire neutrophil function in murine sepsis and COVID-19 patient cells
Formiga, R. O.; Amaral, F. C.; Souza, C. F.; Mendes, D. A. G. B.; Wanderley, C. W. S.; Lorenzini, C. B.; Santos, A. A.; Antonia, J.; Faria, L. F.; Natale, C. C.; Paula, N. M.; Silva, P. C. S.; Fonseca, F. R.; Aires, L.; Heck, N.; Barroso, S. P. C.; Morrot, A.; Sordi, R.; Alisson-Silva, F.; Mansur, D. S.; Cunha, F. Q.; Maurici, R.; Bafica, A.; Macauley, M. S.; Spiller, F.
10.1101/2020.11.12.379115 — immunology — Posted on 2020-11-12
2485 ACE2-Targeting Monoclonal Antibody As A "Pan" Coronavirus Blocker In Vitro and In A Mouse Model
Chen, Y.; Zhang, Y.; Yan, R.; Wang, G.; Zhang, Y.; Zhang, Z.; Li, Y.; Chu, W.; Chen, Y.; Chen, G.; Wang, Q.; Zhou, Q.; Zhang, B.; Wang, C.
10.1101/2020.11.11.375972 — immunology — Posted on 2020-11-12
2488 Mycobacteria-host interactions in human bronchiolar airway organoids
Iakobachvili, N.; Leon Icaza, S. A.; Knoops, K.; Sachs, N.; Mazeres, S.; Simeone, R.; Peixoto, A.; Murris-Espin, M.; Mazieres, J.; Lopez-Iglesias, C.; Ravelli, R. B. G.; Neyrolles, O.; Meunier, E.; Lugo-Villarino, G.; Clevers, H.; Cougoule, C.; Peters, P. J.
10.1101/2020.11.12.379586 — systems biology — Posted on 2020-11-12
2491 The repurposed drugs suramin and quinacrine inhibit cooperatively in vitro SARS-CoV-2 3CLpro
Eberle, R. J.; Olivier, D. S.; Amaral, M. S.; Willbold, D.; Arni, R. K.; Coronado, M. A.
10.1101/2020.11.11.378018 — biochemistry — Posted on 2020-11-12
2493 A Humanized Animal Model Predicts Clonal Evolution and Therapeutic Vulnerabilities in Myeloproliferative Neoplasms
Celik, H.; Krug, E.; Zhang, C. R.; Han, W.; Issa, N.; Koh, W. K.; Bjeije, H.; Kukhar, O.; Allen, M.; Li, T.; Fisher, D. A.; Fowles, J.; Wong, T. N.; Stubbs, M. C.; Koblish, H. K.; Oh, S. T.; Challen, G. A.
10.1101/2020.11.12.378810 — cancer biology — Posted on 2020-11-12
2498 A Recombinant Protein Biomarker DDA Library Increases DIA Coverage of Low Abundance Plasma Proteins
Ahn, S. B.; Kamath, K. S.; Mohamedali, A.; Noor, Z.; Wu, J. X.; Pascovici, D.; Adhikari, S.; Cheruku, H. R.; Guillemin, G. J.; McKay, M. J.; Nice, E. C.; Baker, M. S.
10.1101/2020.11.11.377309 — biochemistry — Posted on 2020-11-12
2501 Multi-Modal Profiling of Human Fetal Liver-Derived Hematopoietic Stem Cells Reveals the Molecular Signature of Engraftment Potential
Vanuytsel, K.; Villacorta-Martin, C.; Lindstrom-Vautrin, J.; Wang, Z.; Garcia-Beltran, W. F.; Vrbanac, V.; Matte, T. M.; Dowrey, T. W.; Kumar, S. S.; Li, M.; Dries, R.; Campbell, J. D.; Belkina, A. C.; Balazs, A. B.; Murphy, G. J.
10.1101/2020.11.11.378620 — cell biology — Posted on 2020-11-12
2502 Visual processing speed is linked to functional connectivity between right frontoparietal and visual networks
Küchenhoff, S.; Sorg, C.; Schneider, S.; Kohl, O.; Müller, H. J.; Finke, K.; Ruiz-Rizzo, A. L.
10.1101/2020.11.11.378406 — neuroscience — Posted on 2020-11-12
2505 Multiomics and digital monitoring during lifestyle changes reveal independent dimensions of human biology and health
Marabita, F.; James, T.; Karhu, A.; Mills, R.; Perheentupa, T.; Stenlund, H.; Boulund, F.; Hellström, C.; Neiman, M.; Virtanen, H.; Kettunen, K.; Laivuori, H.; Helkkula, P.; Byrne, M.; Honko, H.; Kallonen, A.; Ermes, M.; Similä, H.; Lindholm, M.; Widen, E.; Ripatti, S.; Perälä-Heape, M.; Engstrand, L.; Nilsson, P.; Moritz, T.; Miettinen, T.; Sallinen, R.; Kallioniemi, O.
10.1101/2020.11.11.365387 — systems biology — Posted on 2020-11-12
2510 Biophysical characterization of two commercially available preparations of the drug containing Escherichia coli L-Asparaginase 2
Araujo, T. S.; Scapin, S. M.; Andrade, W.; Fasciotti, M.; de Magalhaes, M. T.; Almeida, M. S.; Lima, L. M. T. d. R.
10.1101/2020.11.11.379065 — biophysics — Posted on 2020-11-12
2511 Frustration in protein complexes leads to interaction versatility
Freiberger, M. I.; Wolynes, P. G.; Ferreiro, D. U.; Fuxreiter, M.
10.1101/2020.11.11.378091 — bioinformatics — Posted on 2020-11-12
2513 TIGA: Target illumination GWAS analytics
Yang, J. J.; Grissa, D.; Lambert, C. G.; Bologa, C. G.; Mathias, S. L.; Waller, A.; Wild, D. J.; Jensen, L. J.; Oprea, T. I.
10.1101/2020.11.11.378596 — bioinformatics — Posted on 2020-11-12
2517 Multilevel Twin Models: Geographical Region as a Third Level Variable
Tamimy, Z.; Kevenaar, S. T.; Hottenga, J. J.; Hunter, M. D.; de Zeeuw, E. L.; Neale, M. C.; van Beijsterveldt, C. E. M.; Dolan, C. V.; van Bergen, E.; Boomsma, D. I.
10.1101/2020.11.11.377820 — genetics — Posted on 2020-11-12
2525 Conformational dynamics regulate SHANK3 actin and Rap1 binding
Salomaa, S. I.; Miihkinen, M.; Kremneva, E.; Paatero, I.; Lilja, J.; Jacquemet, G.; Vuorio, J.; Antenucci, L.; Hassani-Nia, F.; Hollos, P.; Isomursu, A.; Vattulainen, I.; Coffey, E. T.; Kreienkamp, H.-J.; Lappalainen, P.; Ivaska, J.
10.1101/2020.11.12.379222 — cell biology — Posted on 2020-11-12
2527 Transcriptome Analysis of NPFR Neurons Reveals a Connection Between proteome Diversity and Social Behavior
Ryvkin, J.; Bentzur, A.; Shmueli, A.; Tennenbaum, M.; Shallom, O.; Dokarker, S.; Levi, M.; Shohat-Ophir, G.
10.1101/2020.11.12.379826 — neuroscience — Posted on 2020-11-12
2528 The Spatial Memory Pipeline: a model of egocentric to allocentric understanding in mammalian brains
Uria, B.; Ibarz, B.; Banino, A.; Zambaldi, V.; Kumaran, D.; Hassabis, D.; Barry, C.; Blundell, C.
10.1101/2020.11.11.378141 — neuroscience — Posted on 2020-11-12
2529 Full activation of an α7-α3β4 nicotinic receptor complex decreases desensitization receptor in human chromaffin cells
Jimenez-Pompa, A.; Sanz-Lazaro, S.; Medina-Polo, J.; Gonzalez-Enguita, C.; Blazquez, J.; McIntosh, J. M.; Albillos, A.
10.1101/2020.11.11.360537 — neuroscience — Posted on 2020-11-12
2531 VGLUT modulates sex differences in dopamine neuron vulnerability to age-related neurodegeneration
Buck, S. A.; Steinkellner, T.; Aslanoglou, D.; Villeneuve, M.; Bhatte, S. H.; Childers, V. C.; Rubin, S. A.; De Miranda, B. R.; O'Leary, E. I.; Neureiter, E. G.; Fogle, K. J.; Palladino, M. J.; Logan, R. W.; Glausier, J. R.; Fish, K. N.; Lewis, D. A.; Greenamyre, J. T.; Bonci, A.; McCabe, B. D.; Cheetham, C. E.; Hnasko, T. S.; Freyberg, Z.
10.1101/2020.11.11.379008 — neuroscience — Posted on 2020-11-12
2532 Distinct brain mechanisms linked to evidence accumulation and crime-type bias in juror decisions
Castrellon, J. J.; Hakimi, S.; Parelman, J. M.; Yin, L.; Law, J. R.; Skene, J. A. G.; Ball, D. A.; Malekpour, A.; Beskind, D. H.; Vidmar, N.; Pearson, J. M.; Skene, J. H. P.; Carter, R. M.
10.1101/2020.11.11.378935 — neuroscience — Posted on 2020-11-12
2536 Tracing the evolution of aneuploid cancers from multiregional sequencing
Chattopadhyay, S.; Karlsson, J.; Valind, A.; Andersson, N.; Gisselsson, D.
10.1101/2020.11.11.376467 — bioinformatics — Posted on 2020-11-12
2539 Pangenome-based genome inference
Ebler, J.; Clarke, W. E.; Rausch, T.; Audano, P. A.; Houwaart, T.; Korbel, J.; Eichler, E. E.; Zody, M. C.; Dilthey, A. T.; Marschall, T.
10.1101/2020.11.11.378133 — bioinformatics — Posted on 2020-11-12
2544 Comprehensive dataset of shotgun metagenomes from stratified freshwater lakes and ponds
Buck, M.; Garcia, S. L.; Fernandez Vidal, L.; Martin, G.; Martinez Rodriguez, G. A.; Saarenheimo, J.; Zopfi, J.; Bertilsson, S.; Peura, S.
10.1101/2020.11.12.379446 — ecology — Posted on 2020-11-12
2545 Dynamic Domain Specificity In Human Ventral Temporal Cortex
Bankson, B. B.; Boring, M. J.; Richardson, R. M.; Ghuman, A. S.
10.1101/2020.11.11.378877 — neuroscience — Posted on 2020-11-12
2546 Novel fragile X syndrome 2D and 3D brain models based on human isogenic FMRP-KO iPSCs
Brighi, C.; Salaris, F.; Soloperto, A.; Cordella, F.; Ghirga, S.; de Turris, V.; Rosito, M.; Porceddu, P. F.; Reggiani, A.; Rosa, A.; Di Angelantonio, S.
10.1101/2020.11.12.379800 — neuroscience — Posted on 2020-11-12
2550 Leukocyte dynamics after intracerebral hemorrhage in a living patient reveal rapid adaptations to tissue milieu
Goods, B. A.; Askenase, M. H.; Markarian, E.; Beatty, H. E.; Drake, R.; Fleming, I.; DeLong, J. H.; Philip, N. H.; Matouk, C. C.; Awad, I. A.; Zuccarello, M.; Hanley, D. F.; Love, J. C.; Shalek, A. K.; Sansing, L. H.
10.1101/2020.11.10.375675 — immunology — Posted on 2020-11-12
2551 Chirality-dependent anti-inflammatory effect of glutathione after spinal cord injury
Kim, S. J.; Ko, W.-K.; Han, G. H.; Lee, D.; Lee, Y.; Sheen, S. H.; Hong, J. B.; Sohn, S.
10.1101/2020.11.11.377721 — neuroscience — Posted on 2020-11-12
2553 The effect of pre-resection obesity on post-resection body composition after 75% small bowel resection in rats
Patel, N. S.; Yanala, U. R.; Aravind, S.; Reidelberger, R. D.; Thompson, J. S.; Carlson, M. A.
10.1101/2020.11.11.377945 — physiology — Posted on 2020-11-12
2556 A dominant-negative SOX18 mutant disrupts multiple regulatory layers essential to transcription factor activity.
McCann, A. J.; Lou, J.; Moustaqil, M.; Blum, A.; Fontaine, F.; Liu, H.; Luu, W.; Koopman, P.; Sierecki, E.; Gambin, Y.; Meunier, F. A.; Liu, Z.; Hinde, E.; Francois, M.
10.1101/2020.11.11.378968 — cell biology — Posted on 2020-11-12
2559 Extracellular matrix remodeling through endocytosis and resurfacing of Tenascin-R
Dankovich, T. M.; Kaushik, R.; Cassinelli Petersen, G.; Giro, P. E.; Abdul Hadi, H.; Bao, G.; Beuermann, S.; Cooper, B. H.; Dityatev, A.; Rizzoli, S. O.
10.1101/2020.11.11.377515 — neuroscience — Posted on 2020-11-12
2560 Human brain organoids reveal accelerated development of cortical neuron classes as a shared feature of autism risk genes
Paulsen, B.; Velasco, S.; Kedaigle, A. J.; Pigoni, M.; Quadrato, G.; Deo, A.; Adiconis, X.; Uzquiano, A.; Kim, K.; Simmons, S. K.; Tsafou, K.; Albanese, A.; Sartore, R.; Abbate, C.; Tucewicz, A.; Smith, S.; Chung, K.; Lage, K.; Regev, A.; Levin, J. Z.; Arlotta, P.
10.1101/2020.11.10.376509 — developmental biology — Posted on 2020-11-12
2562 ERAP2 facilitates a subpeptidome of Birdshot Uveitis-associated HLA-A29
Venema, W.; Hiddingh, S.; de Boer, J. H.; Claas, F.; Mulder, A.; Hollander, A. D.; Stratikos, E.; Sarkizova, S.; Veken, L. v. d.; Janssen, G.; Veelen, P. v.; Kuiper, J. J.
10.1101/2020.08.14.250654 — immunology — Posted on 2020-11-12
2563 Reproductive history determines ErbB2 locus amplification, WNT signalling and tumour phenotype in a murine breast cancer model
Ordonez, L. D.; Melchor, L.; Greenow, K. R.; Kendrick, H.; Tornillo, G.; Bradford, J.; Giles, P.; Smalley, M. J.
10.1101/2020.10.30.361998 — cancer biology — Posted on 2020-11-12
2564 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-12
2565 Task specialization across research careers
Robinson-Garcia, N.; Costas, R.; Sugimoto, C. R.; Lariviere, V.; Nane, G. F.
10.1101/2020.07.01.181669 — scientific communication and education — Posted on 2020-11-12
2569 Validation of lipid-related therapeutic targets for coronary heart disease prevention using human genetics
Gordillo-Maranon, M.; Zwierzyna, M.; Charoen, P.; Drenos, F.; Chopade, S.; Shah, T.; Engmann, J.; Casas, J.-P.; Chaturvedi, N.; Papacosta, O.; Wannamethee, G.; Wong, A.; Sofat, R.; Kivimaki, M.; Price, J. F.; Hughes, A. D.; Gaunt, T. R.; Lawlor, D. A.; Gaulton, A.; Hingorani, A. D.; Schmidt, A. F.; Finan, C.
10.1101/2020.11.11.377747 — genetics — Posted on 2020-11-11
2570 Distinct molecular signatures of fission predict mitochondrial degradation or proliferation
Kleele, T.; Rey, T.; Winter, J.; Zaganelli, S.; Mahecic, D.; Perreten Lambert, H.; Ruberto, F.; Nemir, M.; Wai, T.; Pedrazzini, T.; Manley, S.
10.1101/2020.11.11.372557 — cell biology — Posted on 2020-11-11
2571 FcγR responses to soluble immune complexes of varying size: A scalable cell-based reporter system
Chen, H.; Maul-Pavicic, A.; Holzer, M.; Salzer, U.; Chevalier, N.; Voll, R. E.; Hengel, H.; Kolb, P.
10.1101/2020.11.11.378232 — immunology — Posted on 2020-11-11
2572 Neurons in the dorso-central division of zebrafish pallium respond to change in visual numerosity
Messina, A.; Potrich, D.; Schiona, I.; Sovrano, V. A.; Fraser, S. E.; Brennan, C. H.; Vallortigara, G.
10.1101/2020.11.11.377804 — neuroscience — Posted on 2020-11-11
2573 Chromosome-length genome assembly and structural variations of the primal Basenji dog (Canis lupus familiaris) genome
Edwards, R. J.; Field, M. A. J.; Ferguson, J. M.; Dudchenko, O.; Keilwagen, J.; Rosen, B. D.; Johnson, G. S.; Rice, E.; Hillier, L.; Hammond, J. M.; Tomwarnicki, S. G.; Omer, A.; Skvortsova, K.; Bogdanovic, O.; Zammit, R. A.; Aiden, E. L.; Warren, W. C.; Ballard, J. W. O.
10.1101/2020.11.11.379073 — genomics — Posted on 2020-11-11
2574 Default Mode Network Ventral Hub Connectivity Associated with Memory Impairment in Temporal Lobe Epilepsy Surgery
Neal, E.; Di, L.; Park, Y. J.; Finch, A.; Korneli, F.; Maciver, S.; Bezchlibnyk, Y. B.; Schoenberg, M. R.; Vale, F. L.
10.1101/2020.11.11.377929 — neuroscience — Posted on 2020-11-11
2575 Structure and variability of optogenetic responses identify the operating regime of cortex
Palmigiano, A.; Fumarola, F.; Mossing, D. P.; Kraynyukova, N.; Adesnik, H.; Miller, K.
10.1101/2020.11.11.378729 — neuroscience — Posted on 2020-11-11
2585 Human PRE-PIK3C2B exhibits long-range intra- and inter-chromosomal interactions with genomic regions enriched in repressive marks.
Maini, J.; Pathak, A. K.; Bhattacharyya, K.; Kumar, N.; Narang, A.; Jain, N.; Singh, I.; Dhingra, V.; Brahmachari, V.
10.1101/2020.11.11.378745 — genetics — Posted on 2020-11-11
2586 In vitro evaluation of the response of human tendon-derived stromal cells to a novel electrospun suture for tendon repair
Nezhentsev, A.; Abhari, R. E.; Baldwin, M. J.; Mimpen, J. Y.; Augustyniak, E.; Isaacs, M.; Mouthuy, P.-A.; Carr, A. J.; Snelling, S. J.
10.1101/2020.11.11.378695 — cell biology — Posted on 2020-11-11
2588 Electrotrophy as potential primary metabolism for colonization of conductive surfaces in deep-sea hydrothermal chimneys
PILLOT, G.; Davidson, S.; Shintu, L.; Amin Ali, O.; Godfroy, A.; Combet-Blanc, Y.; Bonin, P.; Liebgott, P.-P.
10.1101/2020.11.11.377697 — microbiology — Posted on 2020-11-11
2589 Quantitative metaproteomics of patient fecal microbiota identifies host and microbial proteins associated with ulcerative colitis
Thuy-Boun, P. S.; Wang, A. Y.; Crissien-Martinez, A.; Xu, J. H.; Chatterjee, S.; Stupp, G. S.; Su, A. I.; Coyle, W. J.; Wolan, D. W.
10.1101/2020.11.11.378836 — microbiology — Posted on 2020-11-11
2590 Seafloor incubation experiment with deep-sea hydrothermal vent fluid reveals effect of pressureand lag time on autotrophic microbial communities
Fortunato, C. S.; Butterfield, D. A.; Larson, B.; Lawrence-Slavas, N.; Algar, C.; Allen, L. Z.; Holden, J. F.; Proskurowski, G.; Reddington, E.; Stewart, L. C.; Topcuoglu, B. D.; Vallino, J. J.; Huber, J. A.
10.1101/2020.11.11.378315 — microbiology — Posted on 2020-11-11
2591 The Palmitoyl Acyltransferase ZDHHC14 Controls Kv1-Family Potassium Channel Clustering at the Axon Initial Segment
Sanders, S. S.; Hernandez, L. M.; Soh, H.; Karnam, S.; Walikonis, R. S.; Tzingounis, A.; Thomas, G. M.
10.1101/2020.11.11.378240 — neuroscience — Posted on 2020-11-11
2594 A functional pre-screening platform for identifying points of vulnerability in the cell death map of human melanoma tumors
Dekel-Bird, N. P.; Bialik, S.; Itzhaki, O.; Salame, T. M.; Yaeli-Slonim, N.; Levin-Salomon, V.; Dasari, S. K.; Besser, M.; Kimchi, A.
10.1101/2020.11.11.377671 — cancer biology — Posted on 2020-11-11
2596 The regulation of liver gene expression by carbohydrates is mouse strain specific
Chi, Y.; Youn, D. Y.; Xiaoli, A. M.; Liu, L.; Pessin, J. B.; Yang, F.; Pessin, J. E.
10.1101/2020.11.11.378497 — genomics — Posted on 2020-11-11
2601 Exposure to Airborne Bacteria Depends upon Vertical Stratification and Vegetation Complexity
Robinson, J. M.; Cando Dumancela, C.; Antwis, R. E.; Cameron, R.; Liddicoat, C.; Poudel, R.; Weinstein, P.; Breed, M. F.
10.1101/2020.11.11.377630 — ecology — Posted on 2020-11-11
2602 Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma
Prummel, K. D.; Crowell, H. L.; Nieuwenhuize, S.; Brombacher, E. C.; Daetwyler, S.; Soneson, C.; Kresoja-Rakic, J.; Ronner, M.; Kocere, A.; Ernst, A.; Labbaf, Z.; Clouthier, D. E.; Firulli, A. B.; Sanchez-Iranzo, H.; O'Rourke, R.; Raz, E.; Mercader, N.; Burger, A.; Felley-Bosco, E.; Huisken, J.; Robinson, M. D.; Mosimann, C.
10.1101/2020.11.11.355693 — developmental biology — Posted on 2020-11-11
2603 Force requirements of endocytic vesicle formation
Abella Guerra, M.; Andruck, L.; Malengo, G.; Skruzny, M.
10.1101/2020.11.11.378273 — cell biology — Posted on 2020-11-11
2604 Structure of the RPAP3:TRBP interaction reveals an involvement of the HSP90/R2TP chaperone complex in dsRNA pathways
ABEL, Y.; CHARRON, C.; BOURGUIGNON-IGEL, V.; QUINTERNET, M.; CHAGOT, M.-E.; VERHEGGEN, C.; BRANLANT, C.; BERTRAND, E.; MANIVAL, X.; CHARPENTIER, B.; REDERSTORFF, M.
10.1101/2020.11.11.367672 — molecular biology — Posted on 2020-11-11
2605 Nsp1 of SARS-CoV-2 Stimulates Host Translation Termination
Shuvalov, A.; Shuvalova, E.; Biziaev, N.; Sokolova, E.; Evmenov, K.; Egorova, T.; Alkalaeva, E.
10.1101/2020.11.11.377739 — molecular biology — Posted on 2020-11-11
2607 Long read metagenomics, the next step?
Haro-Moreno, J. M.; Lopez-Perez, M.; Rodriguez-Valera, F.
10.1101/2020.11.11.378109 — microbiology — Posted on 2020-11-11
2608 Synergism and antagonism of bacterial-viral co-infection in the upper respiratory tract
Manna, S.; McAuley, J.; Jacobson, J.; Nguyen, C. D.; Ullah, M. A.; Williamson, V.; Mulholland, E. K.; Wijburg, O.; Phipps, S.; Satzke, C.
10.1101/2020.11.11.378794 — microbiology — Posted on 2020-11-11
2609 Immune responses in pancreatic cancer may be restricted byprevalence of activated regulatory T-cells, dysfunctionalCD8+ T-cells, and senescent T-cells
Sivakumar, S.; Abu-Shah, E.; Ahern, D.; Arbe-Barnes, E. H.; Mangal, N.; Reddy, S.; Rendek, A.; Easton, A.; Kurz, E.; Silva, M.; Heij, L. R.; Soonawalla, Z.; Bashford-Rogers, R.; Middleton, M. R.; Dustin, M.
10.1101/2020.06.20.163071 — immunology — Posted on 2020-11-11
2614 Interactions between two QTLs for time to anthesis on spike development and fertility in wheat
Basavaraddi, P. A.; Savin, R.; Wingen, L.; Bencivenga, S.; Przewieslik-Allen, S.; Griffiths, S.; Slafer, G.
10.1101/2020.11.11.378208 — physiology — Posted on 2020-11-11
2615 ASCL1 represses a latent osteogenic program in small cell lung cancer in multiple cells of origin
Olsen, R. R.; Kastner, D. W.; Ireland, A. S.; Groves, S. M.; Pozo, K.; Whitney, C. P.; Guthrie, M. R.; Wait, S. J.; Soltero, D.; Witt, B. L.; Quaranta, V.; Johnson, J. E.; Oliver, T. G.
10.1101/2020.11.11.362632 — cancer biology — Posted on 2020-11-11
2619 Multistep mechanism of DNA replication-coupled G-quadruplex resolution
Sato, K.; Martin-Pintado, N.; Post, H.; Altelaar, M.; Knipscheer, P.
10.1101/2020.11.11.378067 — biochemistry — Posted on 2020-11-11
2620 Enzyme catalysis prior to aromatic residues: reverse engineering of a dephosphoCoA kinase
Makarov, M.; Meng, J.; Tretyachenko, V.; Srb, P.; Brezinova, A.; Giacobelli, V. G.; Bednarova, L.; Vondrasek, J.; Dunker, A. K.; Hlouchova, K.
10.1101/2020.11.11.377994 — biochemistry — Posted on 2020-11-11
2621 The structural basis of fatty acid elongation by the ELOVL elongases
Nie, L.; Pike, A. C.; Pascoa, T. C.; Bushell, S. R.; Quigley, A.; Ruda, G. F.; Chu, A.; Cole, V.; Speedman, D.; Moreira, T.; Shrestha, L.; Mukhopadhyay, S. M.; Burgess-Brown, N. A.; Love, J. D.; Brennan, P. E.; Carpenter, E. P.
10.1101/2020.11.11.378570 — biochemistry — Posted on 2020-11-11
2622 Structure of the Human Signal Peptidase Complex Reveals the Determinants for Signal Peptide Cleavage
Liaci, A. M.; Steigenberger, B.; Tamara, S.; Telles de Souza, P. C.; Grollers-Mulderij, M.; Ogrissek, P.; Marrink, S.-J.; Scheltema, R. A.; Foerster, F.
10.1101/2020.11.11.378711 — biochemistry — Posted on 2020-11-11
2623 Manipulation of a cation-{Pi} sandwich reveals conformational flexibility in phenylalanine hydroxylase
Arturo, E. C.; Merkel, G.; Hansen, M. R.; Lisowski, S.; Almeida, D.; Gupta, K.; Jaffe, E. K.
10.1101/2020.02.28.969873 — biochemistry — Posted on 2020-11-11
2626 A FGF2-mediated incoherent feedforward loop inducesErk inhibition and promotes naive pluripotency
Gharibi, B.; Goncalves, E.; Nashun, B.; Montoya, A.; Mankalow, K.; Strohbuecker, S.; Malik Sheriff, R. S.; Cicarrelli, A.; Carvalho, J.; Nye, E.; Kramer, H.; Rosewell, I.; Hajkova, P.; Beltrao, P.; Santos, S.
10.1101/2020.11.11.378869 — developmental biology — Posted on 2020-11-11
2628 An Entropic Safety Catch Controls Hepatitis C Virus Entry and Antibody Resistance.
Stejskal, L.; Kalemera, M. D.; Palor, M.; Walker, L.; Daviter, T.; Lees, W. D.; Moss, D. S.; Kremyda-Vlachou, M.; Kozlakidis, Z.; Rosenberg, W.; Illingworth, C. J. R.; Shepherd, A. J.; Grove, J.
10.1101/2020.11.11.377218 — molecular biology — Posted on 2020-11-11
2629 Characterization and structural basis of a lethal mouse-adapted SARS-CoV-2
Sun, S.; Gu, H.; Cao, L.; Chen, Q.; Yang, G.; Li, R.-T.; Fan, H.; Ye, Q.; Deng, Y.-Q.; Song, X.; Qi, Y.; Li, M.; Lan, J.; Feng, R.; Wang, L.; Zhang, Y.; Zhou, C.; Zhao, L.; Chen, Y.; Shen, M.; Cui, Y.; Yang, X.; Wang, X.; Wang, H.; Wang, X.; Qin, C.
10.1101/2020.11.10.377333 — microbiology — Posted on 2020-11-11
2631 Non-Invasive Plasma Glycomic and Metabolic Biomarkers of Post-treatment Control of HIV
Giron, L. B.; Palmer, C. S.; Yin, X.; Emmanouil, P.; Damra, M.; Goldman, A. R.; Tang, H. Y.; Johnston, R.; Mounzer, K.; Kostman, J. R.; Tebas, P.; Landay, A.; Montaner, L. J.; Jacobson, J. M.; Li, J.; Abdel-Mohsen, M.
10.1101/2020.11.11.378174 — microbiology — Posted on 2020-11-11
2632 Interferon receptor-deficient mice are susceptible to eschar-associated rickettsiosis.
Burke, T. P.; Engstrom, P.; Tran, C. J.; Glasner, D. R.; Espinosa, D. A.; Harris, E.; Welch, M. D.
10.1101/2020.09.23.310409 — microbiology — Posted on 2020-11-11
2636 Rapid generation of potent antibodies by autonomous hypermutation in yeast
Wellner, A.; McMahon, C.; Gilman, M. S. A.; Clements, J. R.; Clark, S.; Nguyen, K. M.; Ho, M. H.; Shin, J.-E.; Feldman, J.; Hauser, B. M.; Caradonna, T. M.; Wingler, L. M.; Schmidt, A. G.; Marks, D. S.; Abraham, J.; Kruse, A. C.; Liu, C. C.
10.1101/2020.11.11.378778 — bioengineering — Posted on 2020-11-11
2637 Stapled peptides based on Human Angiotensin-Converting Enzyme 2 (ACE2) potently inhibit SARS-CoV-2 infection in vitro
Curreli, F.; Victor, S. M. B.; Ahmed, S.; Drelich, A.; Tong, X.; Tseng, C.-T. K.; Hillyer, C. D.; Debnath, A. K.
10.1101/2020.08.25.266437 — pharmacology and toxicology — Posted on 2020-11-11
2639 Mobility and infectiousness in the spatial spread of an emerging fungal pathogen
Langwig, K. E.; White, J. P.; Parise, K. L.; Kaarakka, H. M.; Redell, J. A.; DePue, J. E.; Scullon, W. H.; Foster, J. T.; Kilpatrick, A. M.; Hoyt, J. R.
10.1101/2020.05.07.082651 — ecology — Posted on 2020-11-11
2641 Inositol pyrophosphate kinase (VIH2) impart drought resistance by promoting plant cell wall homeostasis
Shukla, A.; Kaur, M.; Kanwar, S.; Kaur, G.; Sharma, S.; Mazumder, K.; Pandey, P.; Rishi, V.; Pandey, A. K.
10.1101/743294 — plant biology — Posted on 2020-11-11
2646 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Long, X.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-11
2647 On the necessity of recurrent processing during object recognition: it depends on the need for scene segmentation
Seijdel, N.; Loke, J.; van de Klundert, R.; van der Meer, M.; Quispel, E.; van Gaal, S.; de Haan, E. H.; Scholte, H. S.
10.1101/2020.11.11.377655 — neuroscience — Posted on 2020-11-11
2651 A low-dimensional connectome manifold governs the organization and plasticity of social brain functions in humans.
Valk, S. L.; Kanske, P.; Park, B.-y.; Hong, S.-J.; Boeckler-Raettig, A.; Trautwein, F.-M.; Bernhardt, B. C.; Singer, T.
10.1101/2020.11.11.377895 — neuroscience — Posted on 2020-11-11
2653 The unfolded protein response links tumor aneuploidy to local immune dysregulation
Xian, S.; Searles, S. T.; Sahani, P.; Weller, T. C.; Jepsen, K.; Carter, H.; Zanetti, M.
10.1101/2020.11.10.377358 — cancer biology — Posted on 2020-11-11
2654 Building blocks of protein structures - Physics meets Biology
Skrbic, T.; Maritan, A.; Giacometti, A.; Rose, G. D.; Banavar, J. R.
10.1101/2020.11.10.375105 — biophysics — Posted on 2020-11-11
2655 accuEnhancer: Accurate enhancer prediction by integration of multiple cell type data with deep learning
Tung, Y.-A.; Yang, W.-T.; Hsieh, T.-T.; Chang, Y.-C.; Wu, J.-T.; Oyang, Y.-J.; Chen, C.-Y.
10.1101/2020.11.10.375717 — bioinformatics — Posted on 2020-11-11
2657 Precise Estimation of In Vivo Protein Turnover Rates
O'Brien, J.; Narayan, V.; Wong, Y. L.; Seitzer, P.; Sandoval, C.; Haste, N.; Smith, M.; Rad, R.; Gaun, A.; Baker, A.; Kukurugya, M.; Martin-McNulty, B.; Zhang, C.; Kolumam, G.; Sidrauski, C.; Jojic, V.; McAllister, F.; Bennett, B.; Buffenstein, R.
10.1101/2020.11.10.377440 — bioinformatics — Posted on 2020-11-11
2660 Engineered Prime Editors with PAM flexibility
Kweon, J.; Yoon, J.-K.; Jang, A.-H.; Shin, H. R.; See, J.-E.; Jang, G.; KIM, J.-I.; Kim, Y.
10.1101/2020.11.10.377580 — bioengineering — Posted on 2020-11-11
2662 Epigenome-wide study of brain DNA methylation among opioid users and controls
Shu, C.; Sosnowski, D. W.; Tao, R.; Deep-Soboslay, A.; Kleinman, J. E.; Hyde, T. M.; Jaffe, A. E.; Sabunciyan, S.; Maher, B. S.
10.1101/2020.11.10.377069 — genomics — Posted on 2020-11-11
2663 Long-read isoform sequencing reveals survival-associated splicing in breast cancer
Veiga, D. F. T.; Nesta, A.; Zhao, Y.; Deslattes Mays, A.; Huynh, R.; Rossi, R.; Wu, T.-C.; Palucka, K.; Anczukow, O.; Beck, C. R.; Banchereau, J.
10.1101/2020.11.10.376996 — genomics — Posted on 2020-11-11
2668 Centriole and PCM cooperatively recruit CEP192 to spindle poles to promote bipolar spindle assembly
Chinen, T.; Yamazaki, K.; Hashimoto, K.; Fujii, K.; Watanabe, K.; Takeda, Y.; Yamamoto, S.; Nozaki, Y.; Tsuchiya, Y.; Takao, D.; Kitagawa, D.
10.1101/2020.11.10.377341 — cell biology — Posted on 2020-11-11
2671 Comparative genomic analyses provide clues to capsule switch in Streptococcus suis
Zhu, Y.; Dong, W.; Ma, J.; Zhang, Y.; Zhong, X.; Pan, Z.; Liu, G.; Wu, Z.; Yao, H.
10.1101/2020.11.11.377622 — microbiology — Posted on 2020-11-11
2674 The impact of exercise intensity on neurophysiological indices of food-related inhibitory control and cognitive control: A randomized crossover event-related potential (ERP) study
Bailey, B. W.; Muir, A. M.; Bartholomew, C. L.; Christensen, W. F.; Carbine, K. A.; Marsh, H.; LaCouture, H.; McCutcheon, C.; Larson, M. J.
10.1101/2020.11.10.377267 — neuroscience — Posted on 2020-11-11
2679 Analysis of Hippocampal Subfields in Sickle Cell Disease Using Ultrahigh Field MRI
Santini, T.; Koo, M.; Farhat, N.; Campos, V. P.; Alkhateeb, S.; Vieira, M. A. C.; Butters, M. A.; Rosano, C.; Aizenstein, H. J.; Mettenburg, J.; Novelli, E. M.; Ibrahim, T. S.
10.1101/2020.11.10.377564 — neuroscience — Posted on 2020-11-11
2683 Root system influence on high dimensional leaf phenotypes over the grapevine growing season
Harris, Z. N.; Klein, L. L.; Awale, M.; Swift, J. F.; Migicovsky, Z.; Bhakta, N.; Frawley, E.; Chitwood, D. H.; Fennell, A.; Kovacs, L. G.; Kwasniewski, M.; Londo, J. P.; Ma, Q.; Miller, A. J.
10.1101/2020.11.10.376947 — plant biology — Posted on 2020-11-11
2690 Intraoperative enrichment of bone autograft with autologous bone marrow-derived mononuclear cells isolated simultaneously: moving towards tissue engineering in situ
Baranovskii, D. S.; Akhmedov, B. G.; Krasilnikova, O. A.; Demchenko, A. G.; Krasheninnikov, M. E.; Balyasin, M. V.; Pavlova, O. Y.; Serova, N. S.; Klabukov, I. D.
10.1101/2020.11.09.375188 — bioengineering — Posted on 2020-11-11
2695 Potent neutralizing equine antibodies raised against recombinant SARS-CoV-2 spike protein for COVID-19 passive immunization therapy
Cunha, L. E. R.; Stolet, A. A.; Strauch, M. A.; Pereira, V. A. R.; Dumard, C. H.; Gomes, A. M. O.; Souza, P. N. C.; Fonseca, J. G.; Pontes, F. E.; Meirelles, L. G. R.; Albuquerque, J. W. M.; Sacramento, C. Q.; Fintelman-Rodrigues, N.; Lima, T. M.; Alvim, R. G. F.; Marsili, F. F.; Caldeira, M. M.; Higa, L. M.; Monteiro, F. L.; Zingali, R.; Oliveira, G. A. P.; Souza, T. M. L.; Tanuri, A.; Oliveira, A. C.; Guedes, H. L. M.; Castilho, L. R.; Silva, J. L.
10.1101/2020.08.17.254375 — immunology — Posted on 2020-11-11
2696 A reduced level of consciousness affects non-conscious processes
Fontan, A.; Lindgren, L.; Pedale, T.; Brorsson, C.; Bergstrom, F.; Eriksson, J.
10.1101/2020.11.10.376483 — neuroscience — Posted on 2020-11-11
2697 Neuroanatomical abnormalities in a nonhuman primate model of congenital Zika virus infection
Seelke, A.; Beckman, D.; Bennett, J.; Dougherty, P.; Van Rompay, K. K. A.; Keesler, R.; Pesavento, P. A.; Coffey, L. L.; Morrison, J. H.; Bliss-Moreau, E.
10.1101/2020.11.10.374611 — neuroscience — Posted on 2020-11-11
2699 Maternal nutritional stress alters sperm competence in male mice offspring leading to reduced fertility
Muranishi, Y.; Parry, L.; Vachette-dit-Martin, M.; Saez, F.; Coudy-Gandilhon, C.; Sauvanet, P.; Volle, D.; Tournayre, J.; Bottari, S.; Carpentiero, F.; Escoffier, J.; Bruhat, A.; Maurin, A.-C.; Averous, J.; Arnoult, C.; Fafournoux, P.; Jousse, C.
10.1101/2020.11.10.376616 — physiology — Posted on 2020-11-11
2700 Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven lipogenesis
Wieser, B. I.; Pena de la Sancha, P.; Schauer, S.; Reicher, H.; Sattler, W.; Breinbauer, R.; Schweiger, M.; Espenshade, P. J.; Zechner, R.; Hoefler, G.; Vesely, P. W.
10.1101/2020.11.02.363440 — biochemistry — Posted on 2020-11-11
2701 Viruses of the Thermotogota; the vehicles on the highways of gene sharing.
Haverkamp, T. H. A.; Lossouarn, J.; Zhaxybayeva, O.; Lyu, J.; Bienvenu, N.; Geslin, C.; Nesbo, C. L.
10.1101/2020.11.07.368316 — evolutionary biology — Posted on 2020-11-11
2704 A novel Hsp90 phospho-switch modulates virulence in the major human fungal pathogen Candida albicans
Diezmann, S.; Alaalm, L.; Crunden, J. L.; Butcher, M.; Obst, U.; Whealy, R.; Williamson, C. E.; O'Brien, H. E.; Schaffitzel, C.; Ramage, G.
10.1101/2020.09.23.309831 — microbiology — Posted on 2020-11-11
2706 Human liver organoids; a patient-derived primary model for HBV Infection and Related Hepatocellular Carcinoma
De Crignis, E.; Romal, S.; Carofiglio, F.; Moulos, P.; Verstegen, M. M. A.; Khalid, M. M.; Pourfarzad, F.; Rao, S.; Bazrafshan, A.; Koutsothanassis, C.; Gehart, H.; Kan, T. W.; Palstra, R.-J.; Boucher, C.; IJzermans, J.; Huch, M.; Boj, S.; Vries, R.; Clevers, H.; van der Laan, L.; Hatzis, P.; Mahmoudi, T.
10.1101/568147 — cancer biology — Posted on 2020-11-11
2707 Making many out of few: deep generative models for single-cell RNA-sequencing data
Treppner, M.; Salas-Bastos, A.; Hess, M.; Lenz, S. M.; Vogel, T.; Binder, H.
10.1101/2020.05.27.119594 — bioinformatics — Posted on 2020-11-11
2708 Evolutionary divergence of novel open reading frames in cichlids speciation
Puntambekar, S.; Newhouse, R.; Navas, J. S. M.; Chauhan, R.; Vernaz, G.; Willis, T.; Wayland, M. T.; Umrania, Y.; Miska, E. A.; Prabakaran, S.
10.1101/2020.03.13.991182 — evolutionary biology — Posted on 2020-11-11
2710 "Self-inactivating" rabies viruses are susceptible to loss of their intended attenuating modification
Matsuyama, M.; Jin, L.; Lavin, T. K.; Sullivan, H. A.; Hou, Y.; Lea, N. E.; Pruner, M. T.; Dam Ferdinez, M. L.; Wickersham, I. R.
10.1101/550640 — neuroscience — Posted on 2020-11-11
2711 Sucrose represses the expression of the strigolactone signalling gene D3/RMS4/MAX2 to promote tillering
Patil, S. B.; Barbier, F. F.; Zhao, J.; Zafar, S. A.; Uzair, M.; Sun, Y.; Fang, J.; Bertheloot, J.; Sakr, S.; Fichtner, F.; Chabikwa, T. G.; Yuan, S.; Beveridge, C. A. A.; Li, X.
10.1101/2020.11.10.377549 — plant biology — Posted on 2020-11-11
2715 Mixed-stock analysis in the age of genomics: Rapture genotyping enables evaluation of stock-specific exploitation in a freshwater fish population with weak genetic structure
Euclide, P. T.; MacDougall, T.; Robinson, J. M.; Faust, M. D.; Wilson, C. C.; Chen, K.-Y.; Marschall, E. A.; Larson, W. A.; Ludsin, S. A.
10.1101/2020.11.10.376350 — genomics — Posted on 2020-11-11
2716 NyuWa Genome Resource: Deep Whole Genome Sequencing Based Chinese Population Variation Profile and Reference Panel
Zhang, P.; Luo, H.; Li, Y.; Wang, Y.; Wang, J.; Zheng, Y.; Niu, Y.; Shi, Y.; Zhou, H.; Song, T.; Kang, Q.; Xu, T.; He, S.
10.1101/2020.11.10.376574 — genomics — Posted on 2020-11-11
2718 Leprosy in wild chimpanzees
Hockings, K. J.; Mubemba, B.; Avanzi, C.; Pleh, K.; Dux, A.; Bersacola, E.; Bessa, J.; Ramon, M.; Metzger, S.; Patrono, L. V.; Jaffe, J. E.; Benjak, A.; Bonneaud, C. J.; Busso, P.; Couacy-Hymann, E.; Gado, M.; Gagneux, S.; Johnson, R. C.; Kodio, M.; Lynton-Jenkins, J. G.; Morozova, I.; Matz-Rensing, K.; Regalla, A.; Said, A. R.; Schuenemann, V. J.; Sow, S. O.; Spencer, J. S.; Ulrich, M.; Zoubi, H.; Cole, S. T.; Wittig, R.; Calvignac-Spencer, S.; Leendertz, F. H.
10.1101/2020.11.10.374371 — evolutionary biology — Posted on 2020-11-11
2719 Reduced Expression of Slc Genes in the VTA and NAcc of Male Mice with Positive Fighting Experience
Smagin, D. A.; Babenko, V. N.; Kovalenko, I. L.; Galyamina, A. G.; Redina, O. E.; Kudryavtseva, N. N.
10.1101/2020.11.10.377523 — neuroscience — Posted on 2020-11-11
2720 The Mechanical Roles of Chaperons
Haldar, S.; chaudhuri, D.; banerjee, s.; Chakraborty, S.
10.1101/2020.10.20.346973 — biophysics — Posted on 2020-11-11
2728 The Autism Risk Factor CHD8 Is a Chromatin Activator and Functionally Dependent on the ERK-MAPK Pathway Effector ELK1
HADDADDERAFSHI, B.; Danko, T.; Chanda, S.; Batista, P.; Litzenburger, U.; Lee, Q. Y.; Ng, Y. H.; Sebin, A.; Chang, H. Y.; Sudhof, T. C.; Wernig, M.
10.1101/2020.11.10.377010 — cell biology — Posted on 2020-11-10
2730 Coinfection of Streptococcus pneumoniae reduces airborne transmission of influenza virus
Mueller Brown, K.; Le Sage, V.; French, A. J.; Jones, J. E.; Padovani, G. H.; Avery, A. J.; Myerburg, M. M.; Schultz-Cherry, S.; Rosch, J. W.; Hiller, N. L.; Lakdawala, S. S.
10.1101/2020.11.10.376442 — microbiology — Posted on 2020-11-10
2741 High-throughput imaging of mRNA at the single-cell level in human primary immune cells
Gadkari, M.; Sun, J.; Carcamo, A.; Alessi, H.; Hu, Z.; Fraser, I. D. C.; Pegoraro, G.; Franco, L. M.
10.1101/2020.11.10.377283 — genomics — Posted on 2020-11-10
2743 Bispecific tau antibodies with additional binding to C1q or alpha-synuclein
Quint, W. H.; Matecko-Burmann, I.; Schilcher, I.; Loeffler, T.; Scholl, M.; Burmann, B. M.; Vogels, T.
10.1101/2020.11.10.376301 — neuroscience — Posted on 2020-11-10
2744 Spaceflight Affects Neuronal Morphology and Alters Transcellular Degradation of Neuronal Debris in Adult Caenorhabditis elegans
Laranjeiro, R.; Harinath, G.; Pollard, A. K.; Gaffney, C. J.; Deane, C. S.; Vanapalli, S. A.; Etheridge, T.; Szewczyk, N. J.; Driscoll, M.
10.1101/2020.11.10.377143 — neuroscience — Posted on 2020-11-10
2746 Engineering Radioprotective Human Cells Using the Tardigrade Damage Suppressor Protein, DSUP
Westover, C.; Najjar, D.; Meydan, C.; Grigorev, K.; Veling, M.; Chang, R.; Iosim, S.; Colon, R.; Yang, S.; Restrep, U.; Chin, C.; Butler, D.; Moszary, C.; Rahmatulloev, S.; Afshinnekoo, E.; Silver, P.; Mason, C.
10.1101/2020.11.10.373571 — synthetic biology — Posted on 2020-11-10
2752 Rapid evolution by clonal selection within populations of fibroblasts propagated on a novel soft substrate
Purkayastha, P.; Pendyala, K.; Saxena, A. S.; Hakimjavadi, H.; Chamala, S.; Dixit, P. D.; Baer, C. F.; Lele, T. P.
10.1101/2020.04.26.061911 — evolutionary biology — Posted on 2020-11-10
2757 Contractile reprogramming of cardiac pericytes by MEK inhibition promotes arteriologenesis of the ischemic heart
Avolio, E.; Katare, R.; Thomas, A. C.; Caporali, A.; Schwenke, D.; Meloni, M.; Caputo, M.; Madeddu, P.
10.1101/2020.11.10.376772 — cell biology — Posted on 2020-11-10
2759 SF3B1 promotes tumor malignancy through splicing-independent co-activation of HIF1α
Simmler, P.; Cortijo, C.; Koch, L. M.; Galliker, P.; Angori, S.; Bolck, H. A.; Mueller, C.; Vukolic, A.; Mirtschink, P.; Christinat, Y.; Davidson, N. R.; Lehmann, K.-V.; Pellegrini, G.; Pauli, C.; Lenggenhager, D.; Guccini, I.; Ringel, T.; Hirt, C.; Raetsch, G.; Moch, H.; Stoffel, M.; Schwank, G.
10.1101/2020.11.10.376780 — cell biology — Posted on 2020-11-10
2760 The role of cytosolic polyadenylation element binding protein 2 alternative splicing in hypoxia
Mayo, E. M.; Stevens, S. C.; Ali, A. N.; Moss, C. J.; Lund, S. P.; Nazario-Munoz, G. S.; Chalfant, C. E.; Park, M. A.
10.1101/2020.10.05.325290 — cell biology — Posted on 2020-11-10
2761 Scalable In Vitro Production of Defined Mouse Erythroblasts
Francis, H.; Harrold, C.; Beagrie, R.; King, A.; Gosden, M. E.; Blayney, J.; Jeziorska, D.; Babbs, C.; Higgs, D. R.; Kassouf, M.
10.1101/2020.11.10.376749 — molecular biology — Posted on 2020-11-10
2762 SARS-CoV-2 infection causes transient olfactory dysfunction in mice
Qin, C.-F.; Ye, Q.; Zhou, J.; Yang, G.; Li, R.-T.; He, Q.; Zhang, Y.; Wu, S.-J.; Chen, Q.; Shi, J.-H.; Zhang, R.-R.; Zhu, H.-M.; Qiu, H.-Y.; Zhang, T.; Deng, Y.-Q.; Li, X.-F.; Xu, P.; Yang, X.
10.1101/2020.11.10.376673 — microbiology — Posted on 2020-11-10
2763 Genetic Evidence for Selective Transfer of Microbes Between the International Space Station and an Astronaut
Danko, D. C.; Singh, N. K.; Butler, D. J.; Mozsary, C.; Jiang, P.; Keshavarzian, A.; Maienschein-Cline, M.; Chlipala, G.; Afshinnekoo, E.; Bezdan, D.; Garrett-Bakelman, F.; Green, S. J.; Turek, F. W.; Vitaterna, M. H.; Venkateswaran, K.; Mason, C. E.
10.1101/2020.11.10.376954 — microbiology — Posted on 2020-11-10
2764 Streptococcus suis induces expression of cyclooxygenase-2 in porcine lung tissue
Dresen, M.; Schenk, J.; Berhanu Weldearegay, Y.; Vötsch, D.; Baumgärtner, W.; Valentin-Weigand, P.; Nerlich, A.
10.1101/2020.11.10.371575 — microbiology — Posted on 2020-11-10
2766 Mapping Cognitive Brain Functions at Scale
Balasubramani, P. P.; Ojeda, A.; Grennan, G.; Maric, V.; Le, H.; Alim, F.; Zafar-Khan, M.; Diaz-Delgado, J.; Silveira, S.; Ramanathan, D.; Mishra, J.
10.1101/2020.05.14.097014 — neuroscience — Posted on 2020-11-10
2767 Synthesis and preclinical evaluation of MTP38 as a novel PET ligand for phophodiesterase 7 in the brain
Obokata, N.; Seki, C.; Hirata, T.; Maeda, J.; Ishii, H.; Nagai, Y.; Matsumura, T.; Takakuwa, M.; Fukuda, H.; Minamimoto, T.; Kawamura, K.; Zhang, M.-R.; Nakajima, T.; Saijo, T.; Higuchi, M.
10.1101/2020.10.29.354696 — neuroscience — Posted on 2020-11-10
2768 SorCS1 binds the insulin receptor to enhance insulin sensitivity
Kjolby, M.; Breining, P.; Pedersen, K. M.; Wellner, N.; Sorensen, K. M. J.; Vittrup, D. M.; Gjessing, A. M. P.; Januliene, D.; Manavalan, A.; Rotman, M.; Thotakura, G.; Skeldal, S.; Madsen, P.; Thirup, S.; Hermey, G.; Vaegter, C. B.; Moller, A.; Asplund, O.; Prasad, R.; Parlevliet, E.; Rensen, P. C. N.; Fuchtbauer, E.-M.; Madsen, A. N.; Holst, B.; Andersen, O. M.; Hansen, T.
10.1101/2020.11.10.376178 — physiology — Posted on 2020-11-10
2770 Docosahexaenoic acid significantly reduces tumor cell growth in preclinical models of ovarian cancer
Bilyk, O.; Hamedi, B.; Dutta, I.; Newell, M.; Bukhari, A. B.; Gamper, A. M.; McVea, R. C.; Liu, J.; Schueler, J.; Siegers, G. M.; Field, C. J.; Postovit, L.-M.
10.1101/2020.11.10.376152 — cancer biology — Posted on 2020-11-10
2772 4DNvestigator: Time Series Hi-C and RNA-seq DataAnalysis Toolbox
Lindsly, S. M.; Ronquist, S.; Lu, S.; Dilworth, S.; Perlman, M.; Rajapakse, I.
10.1101/2020.01.08.898387 — bioinformatics — Posted on 2020-11-10
2774 Highly potent bispecific sybodies neutralize SARS-CoV-2
Walter, J. D.; Hutter, C. A. J.; Garaeva, A. A.; Scherer, M.; Zimmermann, I.; Wyss, M.; Rheinberger, J.; Ruedin, Y.; Earp, J. C.; Egloff, P.; Sorgenfrei, M.; Hürlimann, L.; Gonda, I.; Meier, G.; Remm, S.; Thavarasah, S.; Zimmer, G.; Slotboom, D. J.; Paulino, C.; Plattet, P.; Seeger, M. A.
10.1101/2020.11.10.376822 — biochemistry — Posted on 2020-11-10
2777 ECM remodeling and spatial cell cycle coordination determine tissue growth kinetics
Ainslie, A. P.; Davis, J. R.; Williamson, J. J.; Ferreira, A.; Torres-Sanchez, A.; Hoppe, A.; Mangione, F.; Smith, M. B.; Martin-Blanco, E.; Salbreux, G.; Tapon, N.
10.1101/2020.11.10.376129 — developmental biology — Posted on 2020-11-10
2780 A polyglutamine domain is required for de novo CIZ1 assembly formation at the inactive X chromosome
Sofi, S.; Williamson, L.; Turvey, G. L.; Scoynes, C.; Hirst, C.; Godwin, J.; Brockdorff, N.; Ainscough, J.; Coverley, D.
10.1101/2020.11.10.376558 — cell biology — Posted on 2020-11-10
2782 Oligomeric hypercomplex of the complete oxidative phosphorylation system in heart mitochondria.
Nesterov, S. V.; Chesnokov, Y. M.; Kamyshinsky, R. A.; Panteleeva, A. A.; Lyamzaev, K. G.; Vasilov, R. G.; Yaguzhinsky, L. S.
10.1101/2020.08.17.253922 — molecular biology — Posted on 2020-11-10
2783 Benchmarking DNA isolation kits used in analyses of the urinary microbiome
Karstens, L.; Siddiqui, N. Y.; Zaza, T.; Barstad, A.; Amundsen, C. L.; Sysoeva, T. A.
10.1101/2020.11.10.375279 — microbiology — Posted on 2020-11-10
2785 Protective efficacy of a SARS-CoV-2 DNA Vaccine in wild-type and immunosuppressed Syrian hamsters
Brocato, R.; Kwilas, S. A.; Kim, R. K.; Zeng, X.; Principe, L. M.; Smith, J. M.; Hooper, J.
10.1101/2020.11.10.376905 — microbiology — Posted on 2020-11-10
2786 Strong influence of vertebrate host phylogeny on gut archaeal diversity
Youngblut, N. D.; Reischer, G. H.; Dauser, S.; Walzer, C.; Stalder, G.; Farnleitner, A. H.; Ley, R. E.
10.1101/2020.11.10.376293 — microbiology — Posted on 2020-11-10
2787 The hydroalcoholic extract of Uncaria tomentosa (Cat's claw) inhibits the replication of novel coronavirus (SARS-CoV-2) in vitro
Yepes-Perez, A. F.; Herrera-Calderon, O.; Florez-Alvarez, L.; Zapata-Cardona, M. I.; Yepes, L.; Aguilar, W.; Rugeles, M. T.; Zapata, W.
10.1101/2020.11.09.372201 — microbiology — Posted on 2020-11-10
2790 Comparison of three air samplers for the collection of four nebulized respiratory viruses
Kutter, J. S.; de Meulder, D.; Bestebroer, T. M.; Mulders, A.; Fouchier, R. A.; Herfst, S.
10.1101/2020.11.10.376053 — microbiology — Posted on 2020-11-10
2791 Evaluation of the antiviral effect of chlorine dioxide (ClO2) using a vertebrate model inoculated with avian coronavirus
Zambrano-Estrada, X.; Dominguez-Sanchez, C. A.; Banuet-Martinez, M.; Guerrero-de la Rosa, F.; Garcia-Gasca, T.; Prieto-Valiente, L.; Acevedo-Whitehouse, K.
10.1101/2020.10.13.336768 — microbiology — Posted on 2020-11-10
2792 CD127 imprints functional heterogeneity to diversify monocyte responses in human inflammatory diseases
Zhang, B.; Zhang, Y.; Xiong, L.; Li, Y.; Zhang, Y.; Zhao, J.; Jiang, H.; Li, C.; Liu, Y.; Liu, X.; Liu, H.; Ping, Y.-F.; Zhang, Q. C.; Zhang, Z.; Bian, X.-W.; Zhao, Y.; Hu, X.
10.1101/2020.11.10.376277 — immunology — Posted on 2020-11-10
2793 Integrative Transcriptomic Analysis Reveals the Immune Mechanism for A CyHV-3-Resistant Common Carp Strain
Jia, Z.; Wu, N.; Jiang, X.; Li, H.; Sun, J.; Shi, M.; Li, C.; Hu, X.; Ge, Y.; Ye, W.; Tang, Y.; Cheng, Y.; Xia, X.-Q.; Shi, L.
10.1101/2020.11.10.375915 — immunology — Posted on 2020-11-10
2794 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2020-11-10
2798 A new microfluidic concept for successful in vitro culture of mouse embryos
Mancini, V.; McKeegan, P.; Rutledge, A. C.; Condreanu, S. G.; Sherrod, S. D.; McLean, J. A.; Picton, H. M.; Pensabene, V.
10.1101/2020.11.10.376160 — bioengineering — Posted on 2020-11-10
2799 A benchmarking study of SARS-CoV-2 whole-genome sequencing protocols using COVID-19 patient samples
Liu, T.; Chen, Z.; Chen, W.; Chen, X.; Hosseini Asanjan, M.; Yang, Z.; Li, J.; Ho, D.; Turay, D.; Gheorghe, C.; Jones, W.; Wang, C.
10.1101/2020.11.10.375022 — genomics — Posted on 2020-11-10
2800 Susceptibility of well-differentiated airway epithelial cell cultures from domestic and wildlife animals to SARS-CoV-2
Gultom, M.; Licheri, M.; Laloli, L.; Wider, M.; Straessle, M.; Steiner, S.; Kratzel, A.; Thao, T. T. N.; Stalder, H.; Portmann, J.; Holwerda, M.; V'kovski, P.; Ebert, N.; Stokar - Regenscheit, N.; Gurtner, C.; Zanolari, P.; Posthaus, H.; Schuller, S.; Moreira - Soto, A.; Vicente - Santos, A.; Corrales - Aguilar, E.; Ruggli, N.; Tekes, G.; von Messling, V.; Sawatsky, B.; Thiel, V.; Dijkman, R.
10.1101/2020.11.10.374587 — microbiology — Posted on 2020-11-10
2806 Inhibition of histone acetyltranserase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a novel gain of function.
Kumar, M.; Molkentine, D.; Molkentine, J.; Bridges, K.; Xie, T.; Yang, L.; Hefner, A.; Gao, M.; Frederick, M. J.; Seth, S.; Abdelhakiem, M.; Beadle, B.; Johnson, F. M.; Wang, J.; Shen, L.; Heffernan, T.; Sheth, A.; Ferris, R.; Myers, J. N.; Pickering, C. R.; Skinner, H. D.
10.1101/2020.04.10.028217 — cancer biology — Posted on 2020-11-10
2807 PHERI - Phage Host Exploration pipeline.
Balaz, A.; Kajsik, M.; Budis, J.; Szemes, T.; Turna, J.
10.1101/2020.05.13.093773 — bioinformatics — Posted on 2020-11-10
2811 3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system
Leung, C.; Robbins, S.; Moss, A.; Heal, M.; Osanlouy, M.; Christie, R.; Farahani, N.; Monteith, C.; Chen, J.; Hunter, P.; Tappan, S.; Vadigepalli, R.; Cheng, Z.; Schwaber, J. S.
10.1101/2020.07.29.227538 — neuroscience — Posted on 2020-11-10
2813 Cancer associated talin point mutations disorganise cell adhesion and migration
Azizi, L.; Cowell, A.; Mykuliak, V. V.; Goult, B. T.; Turkki, P.; Hytonen, V. P.
10.1101/2020.03.25.008193 — cancer biology — Posted on 2020-11-10
2814 Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
Pal, M.; Munoz-Hernandez, H.; Bjorklund, D.; Zhou, L.; Degliesposti, G.; Skehel, J. M.; Hesketh, E. L.; Thompson, R. F.; Pearl, L. H.; Llorca, O.; Prodromou, C.
10.1101/2020.11.09.374355 — biochemistry — Posted on 2020-11-10
2816 Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis
Ryan, S. M.; Almassey, M.; Burch, A. M.; Ngo, G.; Martin, J. M.; Myers, D.; Compton, D.; Barbee, S.; Mortimer, N. T.; Sanyal, S.; Vrailas-Mortimer, A.
10.1101/552729 — genetics — Posted on 2020-11-10
2825 Identification and phenotype of MAIT cells in cattle and their response to bacterial infections
Edmans, M. D.; Connelley, T. K.; Jayaraman, S.; vrettou, C.; Vordermeier, M.; Mak, J. Y. W.; Liu, L.; Fairlie, D. P.; Maze, E. A.; Chrun, T.; Klenerman, P.; Eckle, S. B. G.; Tchilian, E.; Benedictus, L.
10.1101/2020.11.09.374678 — immunology — Posted on 2020-11-10
2830 Diverse chemotypes drive biased signaling by cannabinoid receptors
Miljus, T.; Heydenreich, F. M.; Gazzi, T.; Kimbara, A.; Rogers-Evans, M.; Nettekoven, M.; Zirwes, E.; Osterwald, A.; Rufer, A. C.; Ullmer, C.; Guba, W.; Le Gouill, C.; Fingerle, J.; Nazare, M.; Grether, U.; Bouvier, M.; Veprintsev, D. B.
10.1101/2020.11.09.375162 — pharmacology and toxicology — Posted on 2020-11-10
2840 PHAIR, A biosensor for pH measurement in air-liquid interface of human airway epithelial cells
Dabaghi, M.; Saraei, N.; Xu, G.; Chandiramohan, A.; Yeung, J.; Nguyen, J. P.; Vukmirovic, M.; Selvaganapathy, P. R.; Hirota, J. A.
10.1101/2020.11.09.375683 — bioengineering — Posted on 2020-11-10
2841 Mapping the genetic architecture of human traits to cell types in the kidney identifies mechanisms of disease and potential treatments
Sheng, X.; Ma, Z.; Wu, J.; Liu, H.; Qiu, C.; Miao, Z.; Seasock, M. J.; Palmer, M.; Shin, M. K.; Duffin, K. L.; Pullen, S. S.; Edwards, T. L.; Hellwege, J. N.; Hung, A. M.; Li, M.; Voight, B.; Coffman, T.; Brown, C. D.; Susztak, K.
10.1101/2020.11.09.375592 — genetics — Posted on 2020-11-10
2844 Environmental vulnerability of the global ocean plankton community interactome
Chaffron, S.; Delage, E.; Budinich, M.; Vintache, D.; Henry, N.; Nef, C.; Ardyna, M.; Zayed, A. A.; Junger, P. C.; Galand, P. E.; Lovejoy, C.; Murray, A. E.; Sarmento, H.; Tara Oceans Coordinators, ; Acinas, S. G.; Babin, M.; Iudicone, D.; Jaillon, O.; Karsenti, E.; Wincker, P.; Karp-Boss, L.; Sullivan, M. B.; Bowler, C.; de Vargas, C.; Eveillard, D.
10.1101/2020.11.09.375295 — ecology — Posted on 2020-11-10
2847 Deconstructing the mouse olfactory percept through an olfactory ethological atlas
Manoel, D.; Makhlouf, M.; Arayata, C. J.; Sathappan, A.; Da'as, S.; Abdelrahman, D.; Selvaraj, S.; Hasnah, R.; Mainland, J. D.; Gerkin, R. C.; Saraiva, L. R.
10.1101/2020.11.09.374637 — neuroscience — Posted on 2020-11-10
2849 Novelty Processing Depends on Medial Temporal Lobe Structures
Schomaker, J.; Grouls, M. M. E.; Rau, E.; Hendriks, M.; Colon, A.; Meeter, M.
10.1101/2020.11.10.374538 — neuroscience — Posted on 2020-11-10
2851 AGORA2: Large scale reconstruction of the microbiome highlights wide-spread drug-metabolising capacities.
Heinken, A.; Acharya, G.; Ravcheev, D. A.; Hertel, J.; Nyga, M.; Okpala, O. E.; Hogan, M.; Magnusdottir, S.; Martinelli, F.; Preciat, G.; Edirisinghe, J. N.; Henry, C. S.; Fleming, R. M. T.; Thiele, I.
10.1101/2020.11.09.375451 — systems biology — Posted on 2020-11-10
2852 A plant lipocalin is required for retinal-mediated de novo root organogenesis
Dickinson, A. J.; Zhang, J.; Luciano, M.; Schnermann, M.; Dinneny, J. R.; Benfey, P. N.
10.1101/2020.11.09.375444 — plant biology — Posted on 2020-11-10
2853 EphB6 regulates TFEB-lysosomal pathway and survival of disseminated indolent breast cancer cells
MONTAGNER, M.; Zangrossi, M.; Chakravarty, P.; Romani, P.; Ratcliffe, C. D. H.; Hooper, S.; Dori, M.; Forcato, M.; Bicciato, S.; Dupont, S.; Sahai, E.
10.1101/2020.11.10.376186 — cancer biology — Posted on 2020-11-10
2854 Insights into G-Quadruplex-Hemin Dynamics Using Atomistic Simulations: Implications for Reactivity and Folding
Stadlbauer, P.; Islam, B.; Otyepka, M.; Chen, J.; monchaud, d.; Zhou, J.; Mergny, J.-L.; Sponer, J.
10.1101/2020.11.09.375691 — biophysics — Posted on 2020-11-10
2855 Hypertrophic cardiomyopathy β-cardiac myosin mutation (P710R) leads to hypercontractility by disrupting super-relaxed state: multiscale measurements and computational modeling
Vander Roest, A. S.; Liu, C.; Morck, M. M.; Kooiker, K. B.; Jung, G.; Song, D.; Dawood, A.; Jhingran, A.; Pardon, G.; Ranjbarvaziri, S.; Fajardo, G.; Zhao, M.; Campbell, K. S.; Pruitt, B.; Spudich, J. A.; Ruppel, K. M.; Bernstein, D.
10.1101/2020.11.10.375493 — biophysics — Posted on 2020-11-10
2858 Combined assessment of MHC binding and antigen expression improves T cell epitope predictions
Kosaloglu-Yalcin, Z.; Lee, J.; Nielsen, M.; Greenbaum, J.; Schoenberger, S. P.; Miller, A.; Kim, Y. J.; Sette, A.; Peters, B.
10.1101/2020.11.09.375204 — bioinformatics — Posted on 2020-11-10
2864 Evolution of Natural Lifespan Variation and Molecular Strategies of Extended Lifespan
Kaya, A.; PHUA, C.-Z.-J.; Lee, M.; Wang, L.; Tyshkovskiy, A.; Ma, S.; Liu, W.; Harrison, B.; Zhao, X.; Zhou, X.; Wasko, B. M.; Bammler, T. K.; Promislow, D. E. L.; Kaeberlein, M.; Gladyshev, V. N.
10.1101/2020.11.09.374488 — genetics — Posted on 2020-11-10
2866 Preventing extinctions post-2020 requires recovery actions and transformative change
Bolam, F. C.; Ahumada, J.; Akcakaya, H. R.; Brooks, T. M.; Elliott, W.; Hoban, S.; Mair, L.; Mallon, D.; McGowan, P. J. K.; Raimondo, D.; Rodriguez, J. P.; Roe, D.; Seddon, M. B.; Shen, X.; Stuart, S. N.; Watson, J. E. M.; Butchart, S. H. M.
10.1101/2020.11.09.374314 — ecology — Posted on 2020-11-10
2867 Subsidy Accessibility Drives Asymmetric Food Web Responses
Gutgesell, M. K.; McMeans, B. C.; Guzzo, M. M.; deGroot, V.; Fisk, A. T.; Johnson, T. B.; McCann, K.
10.1101/2020.11.09.374629 — ecology — Posted on 2020-11-10
2869 PCMD-1 bridges the centrioles and the PCM scaffold in C. elegans
Stenzel, L.; Mehler, J.; Schreiner, A.; Uestuener, S.; Zuccoli, E.; Zanin, E.; Mikeladze-Dvali, T.
10.1101/2020.11.09.375865 — cell biology — Posted on 2020-11-10
2871 Alternative splicing liberates a cryptic cytoplasmic isoform of mitochondrial MECR that antagonizes influenza virus
Baker, S. F.; Meistermann, H.; Tzouros, M.; Baker, A.; Golling, S.; Polster, J. S.; Ledwith, M. P.; Gitter, A.; Augustin, A.; Javanbakht, H.; Mehle, A.
10.1101/2020.11.09.355982 — microbiology — Posted on 2020-11-10
2872 Contagious Antibiotic Resistance: Plasmid Transfer Among Bacterial Residents of the Zebrafish Gut
Loftie-Eaton, W.; Crabtree, A.; Perry, D.; Millstein, J.; Robison, B. D.; Forney, L. J.; Top, E. M.
10.1101/2020.11.09.375964 — microbiology — Posted on 2020-11-10
2875 IL-7-adjuvanted vaginal vaccine elicits strong mucosal immune responses in non-human primates
Logerot, S.; Figueiredo, S.; Charmeteau, B.; Sandouk, A.; Drillet-Dangeard, A.-S.; Bomsel, M.; Bourgault-Villada, I.; Couedel-Courteille, A.; Cheynier, R.; Rancez, M.
10.1101/2020.11.09.374405 — immunology — Posted on 2020-11-10
2876 Bulk flow of cerebrospinal fluid observed in periarterial spaces is not an artifact of injection
Raghunandan, A.; Ladron-de-Guevara, A.; Tithof, J.; Mestre, H.; Nedergaard, M.; Thomas, J. H.; Kelley, D. H.
10.1101/2020.11.09.374512 — neuroscience — Posted on 2020-11-10
2880 A Simple and Efficient Pipeline for Construction, Merging, Expansion, and Simulation of Large-Scale, Single-Cell Mechanistic Models
Erdem, C.; Bensman, E. M.; Mutsuddy, A.; Saint-Antoine, M. M.; Bouhaddou, M.; Blake, R. C.; Dodd, W.; Gross, S. M.; Heiser, L. M.; Feltus, F. A.; Birtwistle, M. R.
10.1101/2020.11.09.373407 — systems biology — Posted on 2020-11-10
2882 Full species-wide leaf and seed ionomic diversity of Arabidopsis thaliana
Campos, A. C. A. L.; van Dijk, W. F. A.; Ramakrishna, P.; Giles, T.; Korte, P.; Douglas, A.; Smith, P.; Salt, D. E.
10.1101/2020.11.09.373282 — plant biology — Posted on 2020-11-10
2887 Platypus: an open-access software for integrating lymphocyte single-cell immune repertoires with transcriptomes
Yermanos, A.; Agrafiotis, A.; Yates, J.; Papadopoulou, C.; Robbiani, D.; Bieberich, F.; Vazquez-Lombardi, R.; Neumeier, D.; Oxenius, A.; Reddy, S. T.
10.1101/2020.11.09.374280 — immunology — Posted on 2020-11-10
2888 Human antigen-specific memory natural killer cell responses develop against HIV-1 and influenza virus and are dependent on MHC-E restriction
Jost, S.; Lucar, O.; Yoder, T.; Kroll, K.; Sugawara, S.; Smith, S.; Jones, R.; Tweet, G.; Werner, A.; Tomezsko, P. J.; Dugan, H. L.; Ghofrani, J.; Altfeld, M.; Grundhoff, A.; Muller-Trutwin, M.; Goepfert, P.; Reeves, R. K.
10.1101/2020.11.09.374348 — immunology — Posted on 2020-11-10
2891 Novel proteostasis reporter mouse reveals different effects of cytoplasmic and nuclear aggregates on protein quality control in neurons
Blumenstock, S.; Schulz-Trieglaff, E. K.; Bolender, A.-L.; Voelkl, K.; Lapios, P.; Lindner, J.; Hipp, M. S.; Hartl, U.; Klein, R.; Dudanova, I.
10.1101/2020.11.09.374231 — neuroscience — Posted on 2020-11-10
2899 Point Technology Illuminates The Processing Of Polymerase-Associated Intact Nascent Transcripts
Sousa-Luis, R.; Dujardin, G.; Zukher, I.; Kimura, H.; Carmo-Fonseca, M.; Proudfoot, N.; Nojima, T.
10.1101/2020.11.09.374108 — genomics — Posted on 2020-11-10
2901 Vasopressin acts as a synapse organizer in limbic regions by boosting PSD95 and GluA1 expression
Zhang, L.; Padilla-Flores, T.; Hernandez, V. S.; Campos-Lira, E.; Zetter, M. A.; Escobar, L. I.; Eiden, L. E.
10.1101/2020.11.07.373027 — neuroscience — Posted on 2020-11-10
2903 NASA GeneLab RNA-Seq Consensus Pipeline: Standardized Processing of Short-Read RNA-Seq Data
Overbey, E. G.; Saravia-Butler, A. M.; Zhang, Z.; Rathi, K. S.; Fogle, H.; da Silveira, W. A.; Barker, R. J.; Bass, J. J.; Beheshti, A.; Berrios, D. C.; Blaber, E. A.; Cekanaviciute, E.; Costa, H. A.; Davin, L. B.; Fisch, K. M.; Gebre, S. G.; Geniza, M.; Gilbert, R.; Gilroy, S.; Hardiman, G.; Herranz, R.; Kidane, Y. H.; Kruse, C. P. S.; Lee, M. D.; Liefeld, T.; Lewis, N. G.; McDonald, J. T.; Meller, R.; Mishra, T.; Perera, I.; Ray, S.; Reinsch, S.; Rosenthal, S. B.; Strong, M.; Szewczyk, N. J.; Tahimic, C. G. T.; Taylor, D. M.; Vandenbrink, J. P.; Villacampa, A.; Weging, S.; Wolverton, C.; Wya
10.1101/2020.11.06.371724 — bioinformatics — Posted on 2020-11-10
2904 Machine learning reveals sequence-function relationships in family 7 glycoside hydrolases
Gado, J.; Harrison, B. E.; Sandgren, M.; Stahlberg, J.; Beckham, G. T.; Payne, C. M.
10.1101/2020.11.06.372003 — bioinformatics — Posted on 2020-11-10
2905 Genome-scale metabolic reconstruction analysis of Clostridioides difficile identifies conserved patterns of virulence-related metabolic reprogramming
Jenior, M. L.; Leslie, J. L.; Powers, D. A.; Garrett, E. M.; Walker, K. A.; Dickenson, M. E.; Petri, W. A.; Tamayo, R.; Papin, J. A.
10.1101/2020.11.09.373480 — bioengineering — Posted on 2020-11-10
2906 The role of XPB/Ssl2 double-stranded DNA translocase processivity in transcription start-site scanning.
Tomko, E. J.; Luyties, O.; Rimel, J. K.; Tsai, C.-L.; Fuss, J. O.; Fishburn, J.; Hahn, S.; Tsutakawa, S. E.; Taatjes, D. J.; Galburt, E. A.
10.1101/2020.11.09.375329 — biochemistry — Posted on 2020-11-10
2907 Evolution of the complex transcription network controlling biofilm formation in Candida species
Mancera, E.; Nocedal, I.; Hammel, S.; Gulati, M.; Mitchell, K. F.; Andes, D. R.; Nobile, C. J.; Butler, G.; Johnson, A. D.
10.1101/2020.11.08.373514 — evolutionary biology — Posted on 2020-11-10
2912 Microbiota-mediated competition between pest insects and its application to the evolution-proof protection of crops
rombaut, a.; Gallet, R.; Qitout, K.; Samy, M.; Guilhot, R.; Ghirardini, P.; Becher, P. G.; Xuereb, A.; Gibert, P.; Fellous, S.
10.1101/2020.08.05.238055 — evolutionary biology — Posted on 2020-11-10
2915 B-1 lymphoid cells develop independently of Notch signaling during mouse embryonic development.
Azevedo, N.; Bertesago, E.; Ismailoglu, I.; Kyba, M.; Kobayashi, M.; Ditadi, A.; Yoshimoto, M.
10.1101/2020.11.09.375634 — developmental biology — Posted on 2020-11-09
2916 Canonical Wnt signalling is activated during BEC-to-hepatocyte conversion in vivo and modulates liver epithelial cell plasticity in hepatic organoids
Valle-Encinas, E.; Aleksieva, N.; Velasco Martinez, C.; Dawes, M.; Zverev, M.; Muller, M.; Offergeld, A.; Smalley, M. J.; Hogan, C.; Forbes, S. J.; Bird, T. G.; Dale, T. C.
10.1101/2020.11.09.374462 — cell biology — Posted on 2020-11-09
2918 An in vivo reporter for tracking lipid droplet dynamics in transparent zebrafish
Lumaquin, D.; Johns, E.; Weiss, J.; Montal, E.; Ooladipupo, O.; Abuhashem, A.; White, R.
10.1101/2020.11.09.375667 — cell biology — Posted on 2020-11-09
2920 Influence of tropical pastures on grazing behavior parameters of young lambs
Tontini, J. F.; Poli, C. H. E. C.; Hampel, V. d. S.; Farias, M. d. S.; Fajardo, N. M.; Silva, J. A. d.; Farinatti, L. H. E.; Muir, J. P.; Jalise Fabiola Tontini, Cesar Henrique Espirito Candal Poli, Viviane da Silva Hampel,,
10.1101/2020.11.09.374025 — animal behavior and cognition — Posted on 2020-11-09
2921 Estimation of non-additive genetic variance in human complex traits from a large sample of unrelated individuals
Hivert, V.; Sidorenko, J.; Rohart, F.; Goddard, M. E.; Yang, J.; Wray, N. R.; Yengo, L.; Visscher, P. M.
10.1101/2020.11.09.375501 — genetics — Posted on 2020-11-09
2925 Evaluation of the Abbott ARCHITECT HIV Ag/Ab Combo Assay for Determining Recent HIV-1 Infection
Curtis, K. A.; Rudolph, D. L.; Yi, P.; Delaney, K.; Anastos, K.; DeHovitz, J.; Kassaye, S.; Hanson, C.; French, A.; Golub, E.; Adimora, A.; Ofotokun, I.; Bolivar, H.; Kempf, M.-C.; Peters, P. J.; Switzer, W. M.
10.1101/2020.11.09.374017 — microbiology — Posted on 2020-11-09
2928 Oligodendrocyte secreted factors shape hippocampal GABAergic neuron transcriptome and physiology
Mazuir, E.; Richevaux, L.; Nassar, M.; Robil, N.; de la Grange, P.; Lubetzki, C.; Fricker, D.; Sol-Foulon, N.
10.1101/2020.11.09.374306 — neuroscience — Posted on 2020-11-09
2929 Theta rhythmicity governs the timing of behavioral and hippocampal responses in humans specifically during memory-dependent tasks
ter Wal, M.; Linde Domingo, J.; Lifanov, J.; Roux, F.; Kolibius, L.; Gollwitzer, S.; Lang, J.; Hamer, H.; Rollings, D.; Sawlani, V.; Chelvarajah, R.; Staresina, B.; Hanslmayr, S.; Wimber, M.
10.1101/2020.11.09.374264 — neuroscience — Posted on 2020-11-09
2933 Characterization of the Cannabis sativa glandular trichome proteome
Conneely, L. J.; Mauleon, R.; Mieog, J.; Barkla, B. J.; Kretzschmar, T.
10.1101/2020.11.09.373910 — plant biology — Posted on 2020-11-09
2944 Extending the integrate-and-fire model to account for metabolic dependencies
Jaras, I.; Harada, T.; Orchard, M. E.; Maldonado, P. E.; Vergara, R. C.
10.1101/2020.11.04.367102 — neuroscience — Posted on 2020-11-09
2945 Therapy-induced senescence in normal tissue promotes breast cancer metastasis
Perkins, D. W.; Haider, S.; Roberston, D.; Buus, R.; O'Leary, L.; Isacke, C. M.
10.1101/2020.10.17.343590 — cancer biology — Posted on 2020-11-09
2947 CytoPy: an autonomous cytometry analysis framework
Burton, R. J.; Ahmed, R.; Cuff, S.; Artemiou, A.; Eberl, M.
10.1101/2020.04.08.031898 — bioinformatics — Posted on 2020-11-09
2953 Evidence of genetic overlap between circadian preference and brain white matter microstructure
Garcia-Marin, L. M.; Alcauter, S.; Campos, A. I.; Mulcahy, A.; Kho, P.-F.; Cuellar-Partida, G.; Renteria, M. E.
10.1101/2020.11.09.374199 — neuroscience — Posted on 2020-11-09
2954 RADA is a main branch migration factor in plant mitochondrial recombination and its defect leads to mtDNA instability and cell cycle arrest
Chevigny, N.; Weber-Lotfi, F.; Nadiras, C.; Fertet, A.; Le Ret, M.; Bichara, M.; Erhardt, M.; Dietrich, A.; Raynaud, C.; Gualberto, J. M.
10.1101/856716 — plant biology — Posted on 2020-11-09
2955 Phylogenetic reconstruction of myeloproliferative neoplasm reveals very early origins and lifelong evolution
Williams, N.; Lee, J.; Moore, L.; Baxter, E. J.; Hewinson, J.; Dawson, K. J.; Menzies, A.; Godfrey, A. L.; Green, A. R.; Campbell, P. J.; Nangalia, J.
10.1101/2020.11.09.374710 — cancer biology — Posted on 2020-11-09
2961 SlicerMorph: An open and extensible platform to retrieve, visualize and analyze 3D morphology
Rolfe, S.; Pieper, S.; Porto, A.; Diamond, K.; Winchester, J.; Shan, S.; Kirveslahti, H.; Boyer, D.; Summer, A.; Maga, A. M.
10.1101/2020.11.09.374926 — evolutionary biology — Posted on 2020-11-09
2968 Cloning, Expression and Biophysical Characterization of a Yeast-expressed Recombinant SARS-CoV-2 Receptor Binding Domain COVID-19 Vaccine Candidate
Chen, W.-H.; Wei, J.; Kundu, R. T.; Adhikari, R.; Liu, Z.; Lee, J.; Versteeg, L.; Poveda, C.; Keegan, B.; Villar, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Gillespie, P. M.; Pollet, J.; Strych, U.; Zhan, B.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.11.09.373449 — immunology — Posted on 2020-11-09
2969 Neutrophil extracellular traps induce the epithelial-mesenchymal transition: implications in post-COVID-19 fibrosis
Pandolfi, L.; Bozzini, S.; Vanessa, F.; Percivalle, E.; De Luigi, A.; Violatto, M. B.; Lopez, G.; Gabanti, E.; Carsana, L.; D'Amato, M.; Morosini, M.; De Amici, M.; Nebuloni, M.; Fossali, T.; Colombo, R.; Saracino, L.; Codullo, V.; Gnecchi, M.; Bigini, P.; Baldanti, F.; Lilleri, D.; Meloni, F.
10.1101/2020.11.09.374769 — immunology — Posted on 2020-11-09
2972 Decoding subjective emotional arousal from EEG during an immersive Virtual Reality experience
Hofmann, S. M.; Klotzsche, F.; Mariola, A.; Nikulin, V. V.; Villringer, A.; Gaebler, M.
10.1101/2020.10.24.353722 — neuroscience — Posted on 2020-11-09
2975 Increased and ectopic expression of Triticum polonicum VRT-A2 underlies elongated glumes and grains in hexaploid wheat in a dosage-dependent manner
Adamski, N. M.; Simmonds, J.; Brinton, J. F.; Backhaus, A. E.; Chen, Y.; Smedley, M.; Hayta, S.; Florio, T.; Crane, P.; Scott, P.; Pieri, A.; Hall, O.; Barclay, E. J.; Clayton, M.; Doonan, J. H.; Nibau, C.; Uauy, C.
10.1101/2020.11.09.375154 — plant biology — Posted on 2020-11-09
2976 TRPM2 promotes pancreatic cancer by PKC/MAPK pathway
Lin, R.; Bao, X.; Wang, H.; Zhu, S.; Liu, Z.; Chen, Q.; Ai, K.; Shi, B.
10.1101/2020.11.09.373035 — cancer biology — Posted on 2020-11-09
2977 Correlative 3D microscopy of single cells using super-resolution and scanning ion-conductance microscopy
Navikas, V.; Leitao, S. M.; Grussmayer, K. S.; Descloux, A.; Drake, B.; Yserentant, K.; Werther, P.; Herten, D.-P.; Wombacher, R.; Radenovic, A.; Fantner, G. E.
10.1101/2020.11.09.374157 — biophysics — Posted on 2020-11-09
2978 3D nanoscale analysis of bone healing around degrading Mg implants studied by X-ray scattering tensor tomography
Liebi, M.; Lutz-Bueno, V.; Guizar-Sicairos, M.; Schoenbauer, B. M.; Eichler, J.; Martinelli, E.; Loeffler, J. F.; Weinberg, A.; Lichtenegger, H.; Gruenewald, T. A.
10.1101/2020.11.09.375253 — biophysics — Posted on 2020-11-09
2980 Structure of the TELO2-TTI1-TTI2 complex and its function in TOR recruitment to the R2TP chaperone
Pearl, L. H.; Pal, M.; Munoz-Hernandez, H.; Bjorklund, D.; Zhou, L.; Degliesposti, G.; Skehel, J. M.; Hesketh, E. L.; Thompson, R. F.; Llorca, O.; Prodromou, C.
10.1101/2020.11.09.374355 — biochemistry — Posted on 2020-11-09
2983 Dilp8 controls a time window for tissue size adjustment in Drosophila
Boulan, L.; Blanco-Obregon, D.; El Marzkioui, K.; Brutscher, F.; Andersen, D. S.; Colombani, J.; Narasimha, S.; Leopold, P.
10.1101/2020.11.09.375063 — developmental biology — Posted on 2020-11-09
2984 Importin α7 deficiency causes infertility in male mice by disrupting spermatogenesis
Liu, N.; Qadri, F.; Busch, H.; Huegel, S.; Sihn, G.; Chuykin, I.; Hartmann, E.; Bader, M.; Rother, F.
10.1101/2020.11.09.374652 — developmental biology — Posted on 2020-11-09
2986 Essential role of non-vesicular lipid transport in microtubule-controlled cell polarisation
Hersberger-Trost, M.; Dreher, D.; Huisman, S. M.; Kijowski, A. R.; Gemuenden, M.; Klemm, R. W.; Brunner, D.
10.1101/2020.11.09.374702 — cell biology — Posted on 2020-11-09
2988 Virucidal efficacy of different formulations for hand and surface disinfection targeting SARS CoV-2
Steinhauer, K.; Meister, T. L.; Todt, D.; Krawczyk, A.; Passvogel, L.; Becker, B.; Paulmann, D.; Bischoff, B.; Eggers, M.; Pfaender, S.; Brill, F.; Steinmann, E.
10.1101/2020.11.08.373738 — microbiology — Posted on 2020-11-09
2989 Gain-of-function assay for SARS-CoV-2 Mpro inhibition in living cells
Moghadasi, S. A.; Becker, J. T.; Belica, C.; Wick, C.; Brown, W. L.; Harris, R.
10.1101/2020.11.09.375139 — microbiology — Posted on 2020-11-09
2990 Small Animal Jet Injection Technique Results in Enhanced Immunogenicity of Hantavirus DNA Vaccines
Brocato, R.; Kwilas, S. A.; Josleyn, M. D.; Long, S.; Zeng, X.; Perley, C. C.; Principe, L. M.; Somerville, B. C.; Cohen, M. V.; Hooper, J.
10.1101/2020.11.09.374439 — microbiology — Posted on 2020-11-09
2992 Identification of a unique TCR repertoire, consistent with a superantigen selection process in Children with Multi-system Inflammatory Syndrome
Porritt, R. A.; Paschold, L.; Noval Rivas, M.; Cheng, M. H.; Yonker, L. M.; Chandnani, H.; Lopez, M.; Simnica, D.; Schultheiss, C.; Santiskulvong, C.; Van Eyk, J.; Fasano, A.; Bahar, I.; Binder, M.; Arditi, M.
10.1101/2020.11.09.372169 — immunology — Posted on 2020-11-09
2993 Potentiation of Long-Acting β2-Agonist and Glucocorticoid Responses in Human Airway Epithelial Cells by Modulation of Intracellular cAMP
Kim, Y.; Hou, V.; Huff, R. D.; Aguiar, J. A.; Revill, S.; Tiessen, N.; Cao, C.; Miller, M. S.; Inman, M. D.; Ask, K.; Doxey, A. C.; Hirota, J. A.
10.1101/2020.11.09.375089 — immunology — Posted on 2020-11-09
2994 Development of Targetable Multi-Drug Nanoparticles for Glioblastoma Treatment and In Vitro Evaluation in Glioblastoma Stem Cells
Smiley, S. B.; Yun, Y.; Ayyagari, P.; Shannon, H. E.; Pollok, K. E.; Vannier, M. W.; Das, S. K.; Veronesi, M. C.
10.1101/2020.11.08.373696 — cell biology — Posted on 2020-11-09
2995 Worrying drives cell migration in mechanically unrestrained environments
Welf, E. S.; Driscoll, M. K.; Sapoznik, E.; Murali, V. S.; Weems, A. D.; Roh-Johnson, M.; Dean, K. M.; Fiolka, R. P.; Danuser, G.
10.1101/2020.11.09.372912 — cell biology — Posted on 2020-11-09
2996 The self-peptide repertoire plays a critical role in transplant tolerance induction
Son, E. T.; Faridi, P.; Paul-Heng, M.; Leong, M.; English, K.; Ramarathinam, S. H.; Braun, A.; Dudek, N.; Alexander, I. E.; Lisowski, L.; Bertolino, P.; Bowen, D.; Purcell, A. W.; Mifsud, N.; Sharland, A. F.
10.1101/2020.11.09.359968 — immunology — Posted on 2020-11-09
2998 Spatiotemporal model of cellular mechanotransduction via Rho and YAP
Novev, J. K.; Heltberg, M. L.; Jensen, M. H.; Doostmohammadi, A.
10.1101/2020.11.09.372730 — biophysics — Posted on 2020-11-09
3006 Collagen induced inflammations
Ningchao, D.; Li, Y.; Xu, M.; Wu, C.; Chen, X.; Yang, F.; He, Q.; Liao, M.; Qiu, J.; Wang, C.; Sun, J.; Ma, X.; Sheng, G.; Du, K.; Nandakumar, K. S.; Song, L.
10.1101/2020.11.09.373761 — immunology — Posted on 2020-11-09
3009 Diverse and complex muscle spindle afferent firing properties emerge from multiscale muscle mechanics
Blum, K. P.; Campbell, K. S.; Horslen, B. C.; Nardelli, P.; Housley, S. N.; Cope, T. C.; Ting, L. H.
10.1101/858209 — neuroscience — Posted on 2020-11-09
3015 Adaptive current-flow models of ECT: Explaining individual static impedance, dynamic impedance, and brain current delivery
Unal, G.; Swami, J. K.; Canela, C.; Cohen, S.; Khadka, N.; Rad, M.; Short, B.; Argyelan, M.; Sackeim, H.; Bikson, M.
10.1101/2020.11.08.373712 — bioengineering — Posted on 2020-11-09
3016 Brd4-bound enhancers drive cell intrinsic sex differences in glioblastoma
Kfoury, N.; Qi, Z.; Prager, B. C.; Wilkinson, M.; Broestl, L.; Berrett, K.; Moudgil, A.; Sankararaman, S.; Chen, X.; Gertz, J.; Rich, J. N.; Mitra, R.; Rubin, J. B.
10.1101/199059 — genomics — Posted on 2020-11-09
3020 Maintenance of adaptive dynamics and no detectable load in a range-edge out-crossing plant population
Takou, M.; Hämälä, T.; Koch, E.; Steige, K. A.; Dittberner, H.; Yant, L.; Genete, M.; Sunyaev, S.; Castric, V.; Vekemans, X.; Savolainen, O.; de Meaux, J.
10.1101/709873 — evolutionary biology — Posted on 2020-11-09
3022 A commercial antibody to the human condensin II subunit NCAPH2 cross-reacts with a SWI/SNF complex component
Cutts, E. E.; Taylor, G. C.; Pardo, M.; Yu, L.; Wills, J.; Choudhary, J. S.; Vannini, A.; Wood, A. J.
10.1101/2020.11.07.372599 — cell biology — Posted on 2020-11-09
3023 Nafamostat Mesylate in lipid carrier for nasal SARS-CoV2 titer reduction in a hamster model
Cornelissen, L.; Hoefsmit, E.; Rao, D.; Lijnsvelt, J.; ven Keulen, L.; van Es, M.; Grimm, V.; Medema, R. H.; Blank, C. U.
10.1101/2020.11.09.372375 — microbiology — Posted on 2020-11-09
3024 Human coronaviruses disassemble processing bodies
Robinson, C.-A.; Kleer, M.; Mulloy, R. P.; Castle, E. L.; Boudreau, B. Q.; Corcoran, J. A.
10.1101/2020.11.08.372995 — microbiology — Posted on 2020-11-09
3028 Resistance of endothelial cells to SARS-CoV-2 infection in vitro
Ahmetaj-Shala, B.; Peacock, T. P.; Baillon, L.; Swann, O.; Gashaw, H.; Barclay, W. S.; Mitchell, J. A.
10.1101/2020.11.08.372581 — immunology — Posted on 2020-11-09
3029 Olfactory neuron turnover in adult Drosophila
Fernandez-Hernandez, I.; Hu, E.; Bonaguidi, M. A.
10.1101/2020.11.08.371096 — neuroscience — Posted on 2020-11-09
3030 A Deep Graph Neural Network Architecture for Modelling Spatio-temporal Dynamics in resting-stating functional MRI Data
Azevedo, T.; Campbell, A.; Romero-Garcia, R.; Passamonti, L.; Bethlehem, R. A. I.; Lio, P.; Toschi, N.
10.1101/2020.11.08.370288 — neuroscience — Posted on 2020-11-09
3033 Drought shifts sorghum root metabolite and microbiome profiles and enriches the stress response factor pipecolic acid
Caddell, D. F.; Louie, K.; Bowen, B.; Sievert, J. A.; Hollingsworth, J.; Dahlberg, J.; Purdom, E. F.; Northen, T.; Coleman-Derr, D.
10.1101/2020.11.08.373399 — plant biology — Posted on 2020-11-09
3037 SARS-CoV-2 epitope mapping on microarrays highlights strong immune-response to N protein region
Musico, A.; Frigerio, R.; Mussida, A.; Barzon, L.; Sinigaglia, A.; Riccetti, S.; Gobbi, F.; Piubelli, C.; Bergamaschi, G.; Chiari, M.; Gori, A.; Cretich, M.
10.1101/2020.11.09.374082 — biochemistry — Posted on 2020-11-09
3039 Nodosome inhibition as a novel broad-spectrum antiviral strategy against arboviruses and SARS-CoV-2
Limonta, D.; Dyna-Dagman, L.; Branton, W.; Makio, T.; Wozniak, R. W.; Power, C.; Hobman, T. C.
10.1101/2020.11.05.370767 — microbiology — Posted on 2020-11-09
3041 Alternate primers for whole-genome SARS-CoV-2 sequencing
Cotten, M.; Bugembe, D. L.; Kaleebu, P.; Phan, M. V. T.
10.1101/2020.10.12.335513 — genomics — Posted on 2020-11-09
3042 Mice with Induced Pulmonary Comorbidities Display Severe Lung Inflammation and Mortality following Exposure to SARS-CoV-2
Falach, R.; Bar-On, L.; Lazar, S.; Kadar, T.; Mazor, O.; Aftalion, M.; Gur, D.; Shifman, O.; Israeli, O.; Cohen-Gihon, I.; Zaide, G.; Gutman, H.; Evgy, Y.; Vagima, Y.; Makdasi, E.; Stein, D.; Rosenfeld, R.; Alcalay, R.; Zahavy, E.; Levy, H.; Glinert, I.; Ben-Shmuel, A.; Israely, T.; Melamed, S.; Politi, B.; Achdout, H.; Yitzhaky, S.; Kronman, C.; Sabo, T.
10.1101/2020.10.28.358614 — pathology — Posted on 2020-11-09
3045 Alt-RPL36 downregulates the PI3K-AKT-mTOR signaling pathway by interacting with TMEM24
Cao, X.; Khitun, A.; Luo, Y.; Na, Z.; Phoodokmai, T.; Sappakhaw, K.; Olatunji, E.; Uttamapinant, C.; Slavoff, S. A.
10.1101/2020.03.04.977314 — genomics — Posted on 2020-11-09
3047 Global critical natural assets
Chaplin-Kramer, R.; Neugarten, R.; Sharp, R. P.; Collins, P. M.; Polasky, S.; Hole, D.; Schuster, R.; Strimas-Mackey, M.; Mulligan, M.; Brandon, C.; Diaz, S.; Fluet-Chouinard, E.; Gorenflo, L.; Johnson, J. A.; Keys, P. W.; Longley-Wood, K.; McIntyre, P. B.; Noon, M.; Pascual, U.; Reidy Liermann, C.; Roehrdanz, P.; Schmidt-Traub, G.; Shaw, M. R.; Spalding, M.; Turner, W. R.; van Soesbergen, A.; Watson, R.
10.1101/2020.11.08.361014 — ecology — Posted on 2020-11-09
3050 Exosomal melanotransferrin as a potential biomarker for metastatic melanoma
Bonhoure, A.; Henry, L.; Morille, M.; Assaoui, N.; Bellot, G.; Stoebner, P.-E.; Vidal, M.
10.1101/2020.11.09.373852 — cell biology — Posted on 2020-11-09
3053 Decreased homotopic interhemispheric functional connectivity in children with autism spectrum disorder
Yao, S.; Zhou, M.; Zhang, Y.; Zhang, Q.; Zhao, Z.; Jiang, X.; Xu, X.; Becker, B.; Kendrick, K. M.
10.1101/2020.11.08.373126 — neuroscience — Posted on 2020-11-09
3056 Deterministic scRNA-seq of individual intestinal organoids reveals new subtypes and coexisting distinct stem cell pools
Bues, J.; Biocanin, M.; Pezoldt, J.; Dainese, R.; Chrisnandy, A.; Rezakhani, S.; Saelens, W.; Gardeux, V.; Gupta, R.; Russeil, J.; Saeys, Y.; Amstad, E.; Claassen, M.; Lutolf, M.; Deplancke, B.
10.1101/2020.05.19.103812 — bioengineering — Posted on 2020-11-09
3057 Genome information processing by the INO80 chromatin remodeler positions nucleosomes
Oberbeckmann, E.; Krietenstein, N.; Niebauer, V.; Wang, Y.; Schall, K.; Moldt, M.; Straub, T.; Rohs, R.; Hopfner, K.-P.; Korber, P.; Eustermann, S.
10.1101/2020.11.03.366690 — biochemistry — Posted on 2020-11-09
3058 Drosophila p38 MAPK Interacts with BAG-3/starvin to Regulate Age-dependent Protein Homeostasis
Ryan, S. M.; Almassey, M.; Burch, A. M.; Ngo, G.; Martin, J. M.; Myers, D.; Compton, D.; Barbee, S.; Mortimer, N. T.; Sanyal, S.; Vrailas-Mortimer, A.
10.1101/552729 — genetics — Posted on 2020-11-09
3059 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Long, X.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-09
3066 Interplay between Desmoglein2 and hypoxia controls metastasis in breast cancer
Chang, P.-H.; Chen, M.-C.; Tsai, Y.-P.; Tan, G. Y. T.; Hsu, P.-H.; Jeng, Y.-M.; Tsai, Y.-F.; Yang, M.-H.; Hwang-Verslues, W. W.
10.1101/790519 — cancer biology — Posted on 2020-11-09
3069 Sex determination through X-Y heterogamety in Salix nigra
Sanderson, B. J.; Feng, G.; Hu, N.; Carlson, C. H.; Smart, L. B.; Keefover-Ring, K.; Yin, T.; Ma, T.; Liu, J.; DiFazio, S.; Olson, M. S.
10.1101/2020.03.23.000919 — genomics — Posted on 2020-11-09
3078 Prime Editing in Mice Reveals the Essentiality of a Single Base in Driving Tissue-Specific Gene Expression
Gao, P.; Lyu, Q.; Ghanam, A. R.; Lazzarotto, C. R.; Newby, G. A.; Zhang, W.; Choi, M.; Slivano, O. J.; Holden, K.; Walker, J. A.; Kadina, A. P.; Munroe, R. J.; Abratte, C. M.; Schimenti, J. C.; Liu, D. R.; Tsai, S. Q.; Miano, J. M.
10.1101/2020.11.07.372748 — genetics — Posted on 2020-11-08
3079 Leveraging the Mendelian Disorders of the Epigenetic Machinery to Systematically Map Functional Epigenetic Variation
Luperchio, T. R.; Boukas, L.; Zhang, L.; Pilarowski, G. O.; Jiang, J.; Kalinousky, A.; Hansen, K. D.; Bjornsson, H. T.
10.1101/2020.11.08.373456 — genetics — Posted on 2020-11-08
3084 Cell-free DNA (cfDNA) and exosome profiling from a year-long humanspaceflight reveals circulating biomarkers
Bezdan, D.; Grigorev, K.; Meydan, C.; Pelissier Vatter, F.; Ciofi, M.; Rao, V.; Nakahira, K.; Burnham, P.; Afshinnekoo, E.; Westover, C.; Butler, D.; Moszary, C.; MacKay, M.; Foox, J.; Mishra, T.; Lucotti, S.; Brinda, R.; Melnick, A.; Zhang, H.; Matei, I.; Kelsen, D.; Yu, K.; Lyden, D.; Lynn, T.; Bailey, S.; Snyder, M.; Garrett-Bakelman, F.; Ossowski, S.; De Vlaminck, I.; Mason, C.
10.1101/2020.11.08.373530 — cell biology — Posted on 2020-11-08
3085 Mitochondrial profiling reveals dynamic, sex- and age-specific mitochondrial phenotypes in human immune cell subtypes
Rausser, S.; Trumpff, C.; McGill, M. A.; Junker, A.; Wang, W.; Ho, S.-H.; Mitchell, A.; Karan, K. R.; Monk, C.; Segerstrom, S. C.; Reed, R. G.; Picard, M.
10.1101/2020.10.16.342923 — cell biology — Posted on 2020-11-08
3088 in vitro: Natural Compounds (Thymol, Carvacrol, Hesperidine, And Thymoquinone) Against SARS-CoV2 Strain Isolated From Egyptian Patients
Seadawy, M. G.; Gad, A. F.; Harty, B. E.; Mohamed, M. F.; ELdesoky, M. S.; Elfiky, A. A.; Ahmed, A.; Zekri, A. N.
10.1101/2020.11.07.367649 — microbiology — Posted on 2020-11-08
3091 Invariant Odor Recognition with ON-OFF Neural Ensembles
Nizampatnam, S.; Zhang, L.; Chandak, R.; Katta, N.; Raman, B.
10.1101/2020.11.07.372870 — neuroscience — Posted on 2020-11-08
3092 Longitudinal Auditory Pathophysiology Following Mild Blast Induced Trauma
Han, E. X.; Fernandez, J. M.; Swangberg, C.; Shi, R.; Bartlett, E. L.
10.1101/2020.11.06.371591 — neuroscience — Posted on 2020-11-08
3096 The diagonal band of broca continually regulates olfactory-mediated behaviors by modulating odor-evoked responses within the olfactory bulb
Schwarz, I.; Mueller, M.; Pavlova, I.; Schweihoff, J. F.; Musacchio, F.; Mittag, M.; Fuhrmann, M.; Schwarz, M. K.
10.1101/2020.11.07.372649 — neuroscience — Posted on 2020-11-08
3100 Whole genome sequencing provides evidence of two biologically and clinically distinct entities of asymptomatic monoclonal gammopathies: progressive versus stable myeloma precursor condition
Oben, B.; Froyen, G.; Maclachlan, K. H.; Leongamornlert, D.; Abascal, F.; Zheng-Lin, B.; Yellapantula, V.; Derkach, A.; Geerdens, E.; Diamond, B. T.; Arijs, I.; Maes, B.; Vanhees, K.; Hultcrantz, M.; Manasanch, E. E.; Kazandjian, D.; Dogan, A.; Zhang, Y.; Mikulasova, A.; Walker, B.; Morgan, G.; Campbell, P. J.; Landgren, O.; Rummens, J.-L.; Bolli, N.; Maura, F.
10.1101/2020.11.06.372011 — cancer biology — Posted on 2020-11-08
3103 The Effects of Strain and Estrous Cycle on Heroin- and Sucrose-Maintained Responding in Female Rats
Schmidt, K. T.; Sharp, J. L.; Ethridge, S. B.; Pearson, T.; Ballard, S.; Potter, K. M.; Smith, M. A.
10.1101/2020.11.06.370023 — animal behavior and cognition — Posted on 2020-11-08
3104 Mitotic interhomolog recombination drives genomic diversity in diatoms
Bulankova, P.; Sekulic, M.; Jallet, D.; Nef, C.; Delmont, T. O.; van Oosterhout, C.; Vercauteren, I.; Osuna-Cruz, C. M.; Vancaester, E.; Mock, T.; Sabbe, K.; Daboussi, F.; Bowler, C.; Vyverman, W.; Vandepoele, K.; De Veylder, L.
10.1101/2020.11.08.373134 — genomics — Posted on 2020-11-08
3105 Genomic Insights into the Demographic History of Southern Chinese
Huang, X.; Xia, Z.-Y.; Bin, X.; He, G.; Guo, J.; Lin, C.; Yin, L.; Zhao, J.; Ma, Z.; Ma, F.; Li, Y.; Hu, R.; Wei, L.-H.; Wang, C.-C.
10.1101/2020.11.08.373225 — genomics — Posted on 2020-11-08
3107 Viruses of the Thermotogota; the vehicles on the highways of gene sharing.
Haverkamp, T. H. A.; Lossouarn, J.; Zhaxybayeva, O.; Lyu, J.; Bienvenu, N.; Geslin, C.; Nesbo, C. L.
10.1101/2020.11.07.368316 — evolutionary biology — Posted on 2020-11-08
3111 Connecting omics signatures of diseases, drugs, and mechanisms of actions with iLINCS
Pilarczyk, M.; Kouril, M.; Shamsaei, B.; Vasiliauskas, J.; Niu, W.; Mahi, N. A.; Zhang, L.; Clark, N. A.; Ren, Y.; White, S.; Karim, R. S.; Xu, H.; Biesiada, J.; Bennett, M. F.; Davidson, S.; Reichard, J. F.; Roberts, K.; Stathias, V.; Koleti, A.; Vidovic, D.; Clarke, D. J. B.; Schurer, S. C.; Ma'ayan, A.; Meller, J.; Medvedovic, M.
10.1101/826271 — bioinformatics — Posted on 2020-11-08
3112 TSC1 loss-of-function increases risk for tauopathy by inducing tau acetylation and preventing autophagy-mediated tau clearance
Alquezar, C.; Schoch, K. M.; Geier, E. G.; Ramos, E. M.; Scrivo, A.; Li, K.; Argouarch, A. R.; Mlynarski, E. E.; Dombroski, B.; Yokoyama, J. S.; Cuervo, A. M.; Burlingame, A. L.; Schellenberg, G. D.; Miller, T. M.; Miller, B. L.; Kao, A. W.
10.1101/2020.11.08.371922 — neuroscience — Posted on 2020-11-08
3113 Intrusive Experiences In Post-Traumatic Stress Disorder: Treatment Response Induces Changes In The Effective Connectivity Of The Anterior Insula
Leroy, A.; Very, E.; Birmes, P.; Szaffarczyk, S.; Lopes, R.; Faure, C.; Duhem, S.; Grandgenevre, P.; Warembourg, F.; Vaiva, G.; Jardri, R.
10.1101/2020.10.01.319269 — neuroscience — Posted on 2020-11-08
3114 Clonal expansion of personalized anti-tumor T cells from circulation using tumor organoid-immune co-cultures
Meng, Q.; Xie, S.; Gray, K.; Li, W.; Huang, L.; Akshinthala, D.; Dezfulian, M.; Ferrer, E.; Conahan, C.; Del Pino, S.; Grossman, J.; Elledge, S.; Hidalgo, M.; Muthuswamy, S. K.
10.1101/2020.11.06.371807 — cancer biology — Posted on 2020-11-08
3118 Neuron-gated silicon nanowire field effect transistors to follow single spike propagation within neuronal network
Delacour, C.; Veliev, F.; Crozes, T.; Bres, G.; Minet, J.; Becq, G.; Ionica, I.; Ernst, T.; Briancon Marjollet, A.; Albrieux, M.; Villard, C.
10.1101/2020.11.06.371369 — bioengineering — Posted on 2020-11-08
3119 Micromechanical homogenisation of a hydrogel-filled electrospun scaffold for tissue-engineered epicardial patching of the infarcted heart
Abdalrahman, T.; Mandel, N.; Sack, K. L.; Pugno, N. M.; Bezuidenhout, D.; Limbert, G.; Moscato, F.; Davies, N. H.; Franz, T.
10.1101/2020.11.08.373209 — bioengineering — Posted on 2020-11-08
3122 Assembly of higher-order SMN oligomers is essential for metazoan viability and requires an exposed structural motif present in the YG zipper dimer
Gupta, K.; Wen, Y.; Ninan, N. S.; Raimer, A. C.; Sharp, R.; Spring, A. M.; Sarachan, K. L.; Johnson, M. C.; Van Duyne, G. D.; Matera, A. G.
10.1101/2020.11.07.336172 — biochemistry — Posted on 2020-11-08
3124 Annual and 16-day rangeland production estimates for the western United States
Jones, M. O.; Robinson, N. P.; Naugle, D. E.; Maestas, J. D.; Reeves, M. C.; Lankston, R. W.; Allred, B. W.
10.1101/2020.11.06.343038 — ecology — Posted on 2020-11-08
3126 Interactions between axon-like projections extended by Drosophila Follicle Stem Cells dictate cell fate decisions
Lee, E. H.; Zinshteyn, D.; Wang, M.; Reinach, J.; Chau, C.; Costa, K.; Vargas, A.; Johnson, A.; Alexander, J. I.; O'Reilly, A. M.
10.1101/2020.11.07.372664 — developmental biology — Posted on 2020-11-08
3131 Synaptic dysfunction caused by truncated tau is associated with hyperpolarization-activated cyclic nucleotide-gated channelopathy
Goniotaki, D.; Tamagnini, F.; Biasetti, L.; Rumpf, S. L.; Fennell, K.; Pollack, S.; Ukwesa, S.; Sun, H.; Serpell, L.; Noble, W.; Staras, K.; Hanger, D.
10.1101/2020.11.08.369488 — neuroscience — Posted on 2020-11-08
3132 Cell type specific information transfer for sparse coding
Zeldenrust, F.; Calcini, N.; Yan, X.; Bijlsma, A.; Celikel, T.
10.1101/2020.11.06.371658 — neuroscience — Posted on 2020-11-08
3133 In-vivo histology of iron and myelin in the brain using magnetic susceptibility source separation in MRI
Shin, H.-G.; Lee, J.; Yun, Y. H.; Yoo, S. H.; Jang, J.; Oh, S.-H.; Nam, Y.; Jung, S.; Kim, S.; Fukunaga, M.; Kim, W.; Choi, H. J.; Lee, J.
10.1101/2020.11.07.363796 — neuroscience — Posted on 2020-11-08
3136 Epichloe festucae in mutualistic association with Lolium perenne suppresses host apoplastic cysteine protease activity
Passarge, A.; Demir, F.; Green, K.; Depotter, J. R. L.; Scott, B.; Huesgen, P. F.; Doehlemann, G.; Misas Villamil, J. C.
10.1101/2020.11.06.371211 — plant biology — Posted on 2020-11-08
3140 Recurrent chromosomal imbalances provide selective advantage to human embryonic stem cells under enhanced replicative stress conditions
Mus, L. M.; Van Haver, S.; Popovic, M.; Trypsteen, W.; Lefever, S.; Zeltner, N.; Ogando, Y.; Jacobs, E. Z.; Denecker, G.; Sanders, E.; Van Neste, C.; Vanhauwaert, S.; Decaesteker, B.; Deforce, D.; Van Nieuwerburgh, F.; Mestdagh, P.; Vandesompele, J.; Menten, B.; De Preter, K.; Studer, L.; Heindryckx, B.; Durinck, K.; Roberts, S.; Speleman, F.
10.1101/2020.11.06.360685 — cancer biology — Posted on 2020-11-08
3141 Single-cell analysis of human primary prostate cancer reveals the heterogeneity of tumor-associated epithelial cell states
Song, H.; Weinstein, H. N. W.; Allegakoen, P.; Wadsworth, M. H.; Xie, J.; Yang, H.; Feng, F. Y.; Carroll, P. R.; Wang, B.; Cooperberg, M. R.; Shalek, A. K.; Huang, F. W.
10.1101/2020.11.06.359802 — cancer biology — Posted on 2020-11-08
3146 CoBRA: Containerized Bioinformatics workflow for Reproducible ChIP/ATAC-seq Analysis - from differential peak calling to pathway analysis
Qiu, X.; Feit, A.; Feiglin, A.; Xie, Y.; Kesten, N.; Taing, L.; Perkins, J.; Zhou, N.; Gu, S.; Li, Y.; Cejas, P.; Jeselsohn, R.; Brown, M.; Liu, X. S.; Long, H. W.
10.1101/2020.11.06.367409 — bioinformatics — Posted on 2020-11-08
3148 Optimizing Consensus Generation Algorithms for Highly Variable Amino Acid Sequence Clusters
Mohabati, R.; Rezaei, R.; Mohajel, N.; Ranjbar, M. M.; Azadmanesh, K.; Roohvand, F.
10.1101/2020.11.08.373092 — bioinformatics — Posted on 2020-11-08
3152 VTAM: A robust pipeline for validating metabarcoding data using internal controls
Gonzalez, A.; Dubut, V.; Corse, E.; Mekdad, R.; Dechatre, T.; Meglecz, E.
10.1101/2020.11.06.371187 — ecology — Posted on 2020-11-08
3155 Surfaceome CRISPR Screen Identifies OLFML3 as a Rhinovirus-inducible IFN Antagonist
Mei, H.; Zha, Z.; Wang, W.; Xie, Y.; Huang, Y.; Li, W.; Wei, D.; Zhang, X.; Xie, J.; Qu, M.; Liu, J.
10.1101/2020.11.08.372607 — molecular biology — Posted on 2020-11-08
3157 Widespread Polymodal Chemosensory Receptor Expression in Drosophila Olfactory Neurons
Task, D.; Lin, C.-C.; Afify, A.; Li, H.; Vulpe, A.; Menuz, K.; Potter, C. J.
10.1101/2020.11.07.355651 — neuroscience — Posted on 2020-11-08
3158 Non-canonical odor coding ensures unbreakable mosquito attraction to humans
Younger, M. A.; Herre, M.; Ehrlich, A. R.; Gong, Z.; Gilbert, Z. N.; Rahiel, S.; Matthews, B. J.; Vosshall, L. B.
10.1101/2020.11.07.368720 — neuroscience — Posted on 2020-11-08
3160 Improved bioavailability of montelukast through a novel oral mucoadhesive film in humans and mice
Michael, J.; de Sousa, D. M.; Conway, J.; Gonzalez-Labrada, E.; Obeid, R.; Tevini, J.; Felder, T.; Hutter-Paier, B.; Zerbe, H.; Paiement, N.; Aigner, L.
10.1101/2020.11.06.371500 — pharmacology and toxicology — Posted on 2020-11-08
3162 Genetic factors influencing a neurobiological substrate for psychiatric disorders
Andlauer, T. F. M.; Mühleisen, T. W.; Hoffstaedter, F.; Teumer, A.; Wittfeld, K.; Teuber, A.; Reinbold, C. S.; Grotegerd, D.; Bülow, R.; Caspers, S.; Dannlowski, U.; Herms, S.; Hoffmann, P.; Kircher, T.; Minnerup, H.; Moebus, S.; Nenadic, I.; Teismann, H.; Völker, U.; International FTD-Genomics Consortium (IFGC), ; The 23andMe Research Team, ; Etkin, A.; Berger, K.; Grabe, H. J.; Nöthen, M. M.; Amunts, K.; Eickhoff, S. B.; Sämann, P. G.; Müller-Myhsok, B.; Cichon, S.
10.1101/774463 — genetics — Posted on 2020-11-08
3167 Implementing the precautionary approach into fisheries management: Making the case for probability-based harvest control rules
Mildenberger, T.; Berg, C. W.; Kokkalis, A.; Hordyk, A. R.; Wetzel, C.; Jacobsen, N. S.; Punt, A. E.; Nielsen, J. R.
10.1101/2020.11.06.369785 — ecology — Posted on 2020-11-08
3169 Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk
Twigger, A.-J.; Engelbrecht, L. K.; Bach, K.; Schultz-Pernice, I.; Petricca, S.; Scheel, C. H.; Khaled, W.
10.1101/2020.11.06.371443 — cell biology — Posted on 2020-11-08
3170 Genetic composition and evolution of the prevalent Mycobacterium tuberculosis lineages 2 and 4 in the Chinese and Zhejiang Province populations
Wu, B.; Zhu, W.; Wang, Y.; Wang, Q.; Zhou, L.; Liu, Z. W.; Bi, L.; Barun, M.; Kreiswirth, B. N.; Chen, L.; Chen, S.; Wang, X.; Wang, W.
10.1101/2020.11.07.372573 — molecular biology — Posted on 2020-11-08
3171 Simultaneous, cell-intrinsic downregulation of PD-1 and TIGIT enhances the effector function of CD19-targeting CAR T cells and promotes an early-memory phenotype
Lee, Y.; Lee, H. J.; Kim, H. C.; Lee, Y.; Nam, S. K.; Hupperetz, C.; Ma, J. S.; Wang, X.; Singer, O.; Kim, W. S.; Kim, S. J.; Koh, Y.; Jung, I.; Kim, C. H.
10.1101/2020.11.07.372334 — immunology — Posted on 2020-11-08
3172 K+ efflux through postsynaptic NMDA receptors suppresses local astrocytic glutamate uptake
Tyurikova, O.; Shih, P.-Y.; Dembitskaya, Y.; Savtchenko, L. P.; McHugh, T.; Rusakov, D. A.; Semyanov, A.
10.1101/2020.11.07.372722 — neuroscience — Posted on 2020-11-08
3173 MRS-measured Glutamate versus GABA reflects excitatory versus inhibitory neural activities in awake mice
Takado, Y.; Takuwa, H.; Sampei, K.; Urushihata, T.; Takahashi, M.; Shimojo, M.; Uchida, S.; Nitta, N.; Shibata, S.; Nagashima, K.; Ochi, Y.; Ono, M.; Maeda, J.; Tomita, Y.; Sahara, N.; Near, J.; Aoki, I.; Shibata, K.; Higuchi, M.
10.1101/2020.10.25.353888 — neuroscience — Posted on 2020-11-08
3175 Function and regulation of chloroplast peroxiredoxin IIE
Dreyer, A.; Treffon, P.; Basiry, D.; Jozefowicz, A. M.; Matros, A.; Mock, H.-P.; Dietz, K.-J.
10.1101/2020.11.06.370908 — plant biology — Posted on 2020-11-08
3177 Target-driven design of a coumarinyl chalcone scaffold based novel EF2 Kinase inhibitor suppresses breast cancer growth in vivo
Comert Onder, F.; Kahraman, N.; Bellur Atici, E.; Cagir, A.; Kandemir, H.; Tatar, G.; Taskin Tok, T.; Karliga, B.; Durdagi, S.; Ay, M.; Ozpolat, B.
10.1101/2020.11.06.371062 — cancer biology — Posted on 2020-11-08
3183 Molecular hallmarks of heterochronic parabiosis at single cell resolution
Palovics, R.; Keller, A.; Schaum, N.; Tan, W.; Fehlmann, T.; Borja, M.; Webber, J.; McGeever, A.; Bonanno, L.; The Tabula Muris Consortium, ; Pisco, A. O.; Karkanias, J.; Neff, N. F.; Darmanis, S.; Quake, S. R.; Wyss-Coray, T.
10.1101/2020.11.06.367078 — genomics — Posted on 2020-11-08
3187 NtrX systemically controls transcription of the CtrA system genes to regulate Rhizobium cell division
Luo, L.; Xing, S.; An, F.; Yang, X.; Huang, L.; Zeng, S.; Li, N.; Ouenzar, K.; Yan, J.; Yu, L.
10.1101/2020.11.06.341933 — molecular biology — Posted on 2020-11-08
3188 Functional characterization of RebL1 highlights the evolutionary conservation of oncogenic activities of the RBBP4/7 orthologue in Tetrahymena thermophila
Nabeel-Shah, S.; Garg, J.; Saettone, A.; Ashraf, K.; Lee, H.; Wahab, S.; Ahmed, N.; Fine, J.; Derynck, J.; Ponce, M.; Pu, S.; Marcon, E.; Zhang, Z.; Greenblatt, J. F.; Pearlman, R. E.; Lambert, J.-P.; Fillingham, J.
10.1101/2020.11.07.372946 — molecular biology — Posted on 2020-11-08
3191 Landscape analysis of escape variants identifies SARS-CoV-2 spike mutations that attenuate monoclonal and serum antibody neutralization
Liu, Z.; VanBlargan, L. A.; Rothlauf, P. W.; Bloyet, L.-M.; Chen, R. E.; Stumpf, S.; Zhao, H.; Errico, J. M.; Theel, E. S.; Ellebedy, A. H.; Fremont, D. H.; Diamond, M. S.; Whelan, S. P. J.
10.1101/2020.11.06.372037 — microbiology — Posted on 2020-11-08
3193 Phosphorylation of the canonical histone H2A marks foci of damaged DNA in malaria parasite
Goyal, M.; Heinberg, A.; Mitesser, V.; Kandelis-Shalev, S.; Singh, B. K.; Dzikowski, R.
10.1101/2020.11.06.372391 — microbiology — Posted on 2020-11-08
3196 Two-component spike nanoparticle vaccine protects macaques from SARS-CoV-2 infection
Brouwer, P. J. M.; Brinkkemper, M.; Maisonnasse, P.; Dereuddre-Bosquet, N.; Grobben, M.; Claireaux, M.; de Gast, M.; Marlin, R.; Chesnais, V.; Diry, S.; Allen, J. D.; Watanabe, Y.; Griezen, J. M.; Kerster, G.; Turner, H. L.; van der Straten, K.; van der Linden, C. A.; Aldon, Y.; Naninck, T.; Bontjer, I.; Burger, J. A.; Poniman, M.; Mykytyn, A. Z.; Okba, N. M. A.; Schermer, E. E.; van Breemen, M. J.; Ravichandran, R.; Caniels, T. G.; van Schooten, J.; Kahlaoui, N.; Contreras, V.; Lemaitre, J.; Chapon, C.; Ho Tsong Fang, R.; Villaudy, J.; Sliepen, K.; van der Velden, Y. U.; Haagmans, B.; de Bree
10.1101/2020.11.07.365726 — immunology — Posted on 2020-11-08
3197 Transarterial embolization modulates the immune response within target and non-target hepatocellular carcinomas.
Tischfield, D.; Gurevich, A.; Johnson, O.; Gayatman, I.; Nadolski, G.; Kaplan, D.; Furth, B.; Hunt, S.; Gade, T.
10.1101/2020.11.07.372896 — immunology — Posted on 2020-11-08
3198 Expansion of Human Papillomavirus-Specific T Cells in Periphery and Cervix in a Therapeutic Vaccine Recipient Whose Cervical High-Grade Squamous Intraepithelial Lesion Regressed
Shibata, T.; Shah, S.; Evans, T.; Coleman, H. N.; Lieblong, B. J.; Spencer, H. J.; Quick, C. M.; Sasagawa, T.; Stephens, O. W.; Peterson, E.; Johann, D.; Lu, Y.-C.; Nakagawa, M.
10.1101/2020.11.07.364844 — immunology — Posted on 2020-11-08
3199 A zebrafish model for COVID-19 recapitulates olfactory and cardiovascular pathophysiologies caused by SARS-CoV-2
Kraus, A.; Casadei, E.; Huertas, M.; Ye, C.; Bradfute, S. B.; Boudinot, P.; Levraud, J.-P.; Salinas, I.
10.1101/2020.11.06.368191 — immunology — Posted on 2020-11-08
3200 Variability of Accessory Proteins Rules the SARS-CoV-2 Pathogenicity
Hassan, S. S.; Pal Choudhury, P.; Uversky, V. N.; Dayhoff, G. W.; Aljabali, A. A. A.; Uhal, B.; Lundstrom, K.; Rezaei, N.; Seyran, M.; Pizzol, D.; Adadi, P.; Lal, A.; Soares, A.; Abd El-Aziz, T. M.; Kandimalla, R.; Tambuwala, M.; Azad, G. K.; Sherchan, S. P.; Baetas-da-Cruz, W.; Takayama, K.; Serrano Aroca, A.; Chauhan, G.; Palu, G.; Brufsky, A.
10.1101/2020.11.06.372227 — bioinformatics — Posted on 2020-11-08
3202 A human iPSC-astroglia neurodevelopmental model reveals divergent transcriptomic patterns in schizophrenia
Szabo, A.; Akkouh, I. A.; Vandenberghe, M.; Osete, J. R.; Hughes, T.; Heine, V.; Smeland, O. B.; Glover, J. C.; Andreassen, O.; Djurovic, S.
10.1101/2020.11.07.372839 — neuroscience — Posted on 2020-11-07
3203 Ferroportin 3 is a dual-targeted mitochondrial/chloroplast iron exporter necessary for iron homeostasis in Arabidopsis
Kim, L. J.; Tsuyuki, K. M.; Hu, F.; Park, E. Y.; Zhang, J.; Gallegoe Iraheta, J.; Chia, J.-C.; Huang, R.; Tucker, A. E.; Clyne, M.; Castellano, C.; Kim, A.; Chung, D. D.; DaVeiga, C. T.; Parsons, E. M.; Vatamaniuk, O. K.; Jeong, J.
10.1101/2020.07.15.203646 — plant biology — Posted on 2020-11-07
3206 Complex population structure of the Atlantic puffin revealed by whole genome analyses
Kersten, O.; Star, B.; Leigh, D. M.; Anker-Nilssen, T.; Stroem, H.; Danielsen, J.; Descamps, S.; Erikstad, K. E.; Fitzsimmons, M. G.; Fort, J.; Hansen, E. S.; Harris, M. P.; Irestedt, M.; Kleven, O.; Mallory, M. L.; Jakobsen, K. S.; Boessenkool, S.
10.1101/2020.11.05.351874 — genomics — Posted on 2020-11-07
3209 Bayesian model selection favors parametric over categorical fMRI subsequent memory models in young and older adults
Soch, J.; Richter, A.; Schuetze, H.; Kizilirmak, J. M.; Assmann, A.; Knopf, L.; Raschick, M.; Schult, A.; Maass, A.; Ziegler, G.; Richardson-Klavehn, A.; Duezel, E.; Schott, B. H.
10.1101/2020.07.27.220871 — neuroscience — Posted on 2020-11-07
3211 βPix sequesters IDOL and prevents LDL receptor degradation through a β2AR-regulated signaling pathway in Alport Syndrome
Chahdi, A.; Yousefi, K.; Capcha, J. M. C.; Irion, C. I.; Lambert, G.; Shehadeh, S. A.; Dunkley, J. C.; Lee, Y.-S.; Khan, A.; Ramic, M.; De Andrade, N. S.; Zeier, Z.; Dykxhoorn, D.; Katsoufis, C. P.; Freundlich, M.; Hare, J. M.; Nabity, M. B.; Rivera, C.; Lymperopoulos, A.; Shehadeh, L. A.
10.1101/2020.11.06.372292 — molecular biology — Posted on 2020-11-07
3214 Candidate Explorer: a tool for discovery, evaluation, and display of mutations causing significant immune phenotypes
Xu, D.; Lyon, S.; Bu, C. H.; Hildebrand, S.; Choi, J. H.; Zhong, X.; Liu, A.; Turer, E. E.; Zhang, Z.; Nair-Gill, E.; Shi, H.; Wang, Y.; Zhang, D.; Yue, T.; SoRelle, J.; Misawa, T.; Sun, L.; Wang, J.; Farokhnia, R.; Sakla, A.; Schneider, S.; Stewart, N.; Coco, H.; Coolbaugh, G.; Hayse, B.; Mazal, S.; Medler, D.; Nguyen, B.; Rodriguez, E.; Wadley, A.; Tang, M.; Li, X.; Anderton, P.; Keller, K.; Scott, L.; Quan, J.; Cooper, S.; Qin, B.; Cardin, J.; Simpson, R.; Tadesse, M.; Sun, Q.; Santoyo, J.; Bronikowski, A.; Johnson, A.; Moresco, E. M. Y.; Beutler, B.
10.1101/2020.11.07.371914 — genetics — Posted on 2020-11-07
3215 TRAF6 and TAK1 contribute to SAMHD1-mediated negative regulation of NF-kB signaling
Espada, C. E.; St. Gelais, C.; Bonifati, S.; Maksimova, V. V.; Cahill, M. P.; Kim, S. H.; Wu, L.
10.1101/2020.11.07.368704 — microbiology — Posted on 2020-11-07
3216 Doxycycline inhibits α-synuclein-associated pathologies in vitro and in vivo
Dominguez Meijide, A.; Parrales, V.; Vasili, E.; Gonzalez-Lizarraga, F.; König, A.; Lazaro, D. F.; Lannuzel, A.; Haik, S.; Del-Bel, E. A.; Chehin, R.; Raisman-Vozari, R.; Michel, P. P.; Bizat, N.; Outeiro, T. F.
10.1101/2020.11.06.371229 — molecular biology — Posted on 2020-11-07
3219 European Primary Forest Database (EPFD) v2.0
Sabatini, F. M.; Bluhm, H.; Kun, Z.; Aksenov, D.; Atauri, J. A.; Buchwald, E.; Burrascano, S.; Cateau, E.; Diku, A.; Marques Duarte, I.; Fernandez Lopez, A. B.; Garbarino, M.; Grigoriadis, N.; Horvath, F.; Keren, S.; Kitenberga, M.; Kis, A.; Kraut, A.; Ibisch, P. L.; Larrieu, L.; Lombardi, F.; Matovic, B.; Melu, R. N.; Meyer, P.; Midteng, R.; Mikac, S.; Mikolas, M.; Mozgeris, G.; Panayotov, M.; Pisek, R.; Nunes, L.; Ruete, A.; Schickhofer, M.; Simovski, B.; Stillhard, J.; Stojanovic, D.; Szwagrzyk, J.; Tikkanen, O.-P.; Toromani, E.; Volosyanchuk, R.; Vrska, T.; Waldherr, M.; Yermokhin, M.; Zla
10.1101/2020.10.30.362434 — ecology — Posted on 2020-11-07
3221 Phylogenomics of scorpions reveal a co-diversification of scorpion mammalian predators and mammal-specific sodium channel toxins
Sanitbanez-Lopez, C. E.; Aharon, S.; Ballesteros, J. A.; Gainett, G.; Baker, C. M.; Gonzalez-Santillan, E.; Harvey, M. S.; Hassan, M. K.; Abu-Almaaty, A. H.; Aldeyarbi, S. M.; Monod, L.; Ojanguren-Affilastro, A.; Raven, R. J.; Pinto-da-Rocha, R.; Zvik, Y.; Gavish-Regev, E.; Sharma, P. P.
10.1101/2020.11.06.372045 — evolutionary biology — Posted on 2020-11-07
3224 A novel Mn-dependent peroxidase contributes to tardigrade anhydrobiosis
Yoshida, Y.; Satoh, T.; Ota, C.; Tanaka, S.; Horikawa, D.; Tomita, M.; Kato, K.; Arakawa, K.
10.1101/2020.11.06.370643 — molecular biology — Posted on 2020-11-07
3227 Genetic demultiplexing of pooled single-cell RNA-sequencing samples in cancer facilitates effective experimental design
Weber, L. M.; Hippen, A. A.; Hickey, P. F.; Berrett, K. C.; Gertz, J.; Doherty, J. A.; Greene, C. S.; Hicks, S. C.
10.1101/2020.11.06.371963 — bioinformatics — Posted on 2020-11-07
3229 Finger Sweat Analysis Enables Short Interval Metabolic Biomonitoring in Humans
Brunmair, J.; Niederstaetter, L.; Neuditschko, B.; Bileck, A.; Slany, A.; Janker, L.; Feuerstein, M. L.; Langbauer, C.; Gotsmy, M.; Zanghellini, J.; Meier-Menches, S. M.; Gerner, C.
10.1101/2020.11.06.369355 — biochemistry — Posted on 2020-11-07
3230 Fluorescent Antibody Multiplexing with Oligo-Based Combinatorial Labeling
McCarthy, M.; Anglin, C.; Pear, H.; Boleman, S.; Klaubert, S.; Birtwistle, M. R.
10.1101/2020.11.06.371906 — biochemistry — Posted on 2020-11-07
3231 Visualising Cholesterol in Brain by On-Tissue Derivatisation and Quantitative Mass Spectrometry Imaging
Angelini, R.; Yutuc, E.; Wyatt, M. F.; Newton, J.; Yusuf, F. A.; Griffiths, L.; Cooze, B. J.; El Assad, D.; Frache, G.; Rao, W.; Allen, L. B.; Korade, Z.; Nguyen, T. T.; Rathnayake, R. A.; Cologna, S. M.; Howell, O. W.; Clench, M. R.; Wang, Y.; Griffiths, W. J.
10.1101/2020.11.06.369447 — biochemistry — Posted on 2020-11-07
3235 Glypicans specifically regulate Hedgehog signaling through their interaction with Ihog in cytonemes
Simon, E.; Jimenez-Jimenez, C.; Seijo-Barandiaran, I.; Aguilar, G.; Sanchez-Hernandez, D.; Aguirre-Tamaral, A.; Gonzalez-Mendez, L.; Ripoll, P.; Guerrero, I.
10.1101/2020.11.04.367797 — developmental biology — Posted on 2020-11-07
3236 Hedgehog signalling regulates patterning of the murine and human dentitions through Gas1 co-receptor function
Seppala, M. H.-M.; Thivichon-Prince, B.; Xavier, G. G. M.; Shaffie, N.; Sangani, I.; Birjandi, A. A.; Rooney, J.; Lau, J. N. S.; Dhalivar, R.; Rossi, O.; Riaz, A.; Stonehouse-Smith, D.; Wang, Y.; Viriot, L.; Cobourne, M. T.
10.1101/2020.11.06.371476 — developmental biology — Posted on 2020-11-07
3237 Cryo-EM structure of the mature and infective Mayaro virus at 4.4 A resolution reveals new features of arthritogenic alphaviruses
Filho, H. R.; Coimbra, L. D.; Cassago, A.; Rocha, R. P. F.; Padilha, A. C.; Guerra, J. V. d. S.; Leme, L.; Trivella, D. B. B.; Portugal, R. V.; Lopes-de-Oliveira, P. S.; Marques, R. E.
10.1101/2020.11.06.371773 — microbiology — Posted on 2020-11-07
3238 The unintended consequences of a surge in antibiotic resistance when removing wastewater drain biofilm
KOTAY, S. M.; Parikh, H. I.; Gweon, H. S.; Barry, K.; Stoesser, N.; Walker, A. S.; Crook, D. W.; Vegesana, K.; Mathers, A. J.
10.1101/2020.11.06.372326 — microbiology — Posted on 2020-11-07
3239 The impact of Staphylococcus aureus cell wall glycosylation on langerin recognition and Langerhans cell activation
Hendriks, A.; van Dalen, R.; Ali, S.; Gerlach, D.; van der Marel, G. A.; Fuchsberger, F. F.; Aerts, P.; de Haas, C. J. C.; Peschel, A.; Rademacher, C.; van Strijp, J.; Codee, J. D.; van Sorge, N. M.
10.1101/2020.11.06.371559 — microbiology — Posted on 2020-11-07
3240 The spatial-temporal dynamics of respiratory syncytial virus infections across the east-west coasts of Australia during 2016-17
Robertson, M.; Eden, J.-S.; Levy, A.; Carter, I.; Tulloch, R. L.; Cutmore, E. J.; Horsburgh, B. A.; Sikazwe, C. T.; Dwyer, D. E.; Smith, D. W.; Kok, J.
10.1101/2020.11.06.372177 — microbiology — Posted on 2020-11-07
3241 Immunoregulatory effects of Imuno TF (transfer factors) on Th1/Th2/Th17/Treg cytokines
Oliveira, C. R.; Vieira, R. P.; Ferreira, A. d. O.; Goncalves, A. E. d. S. S.; Polonini, H.
10.1101/2020.11.06.371435 — immunology — Posted on 2020-11-07
3243 Matchathon: A guide to student-faculty connections in PhD programs
Amemiya, H. M.; Lapp, Z.; Smith, C. S.; Durdan, M. M.; DiMondo, M.; Bodiya, B.; Barolo, S.
10.1101/2020.11.06.371526 — scientific communication and education — Posted on 2020-11-07
3244 An antibiotic-resistance conferring mutation in a neisserial porin: Structure, ion flux, and ampicillin binding
Bartsch, A.; Ives, C. M.; Kattner, C.; Pein, F.; Tanabe, M.; Munk, A.; Zachariae, U.; Steinem, C.; Llabres, S.
10.1101/2020.11.06.369579 — biophysics — Posted on 2020-11-07
3247 Genomic and phenotypic analysis of COVID-19-associated pulmonary aspergillosis isolates of Aspergillus fumigatus
Steenwyk, J. L.; Mead, M. E.; Castro, P. A.; Valero, C.; Damasio, A.; Santos, R. A. C.; LaBella, A. L.; Li, Y.; Knowles, S. L.; Raja, H. A.; Oberlies, N. H.; Zhou, X.; Cornely, O. A.; Fuchs, F.; Koehler, P.; Goldman, G.; Rokas, A.
10.1101/2020.11.06.371971 — microbiology — Posted on 2020-11-06
3250 The host exocyst complex is targeted by a conserved bacterial type III effector protein that promotes virulence
A. Michalopoulou, V. A.; Kotsaridis, K.; Mermigka, G.; Kotsifaki, D.; Kokkinidis, M.; Celie, P. H. N.; Jones, J. D. G.; Sarris, P. F.
10.1101/2020.11.06.371260 — microbiology — Posted on 2020-11-07
3253 Differing impacts of global and regional responses on SARS-CoV-2 transmission cluster dynamics
Rife Magalis, B.; Ramirez-Mata, A.; Zhukova, A.; Mavian, C.; Marini, S.; Lemoine, F.; Prosperi, M.; Gascuel, O.; Salemi, M.
10.1101/2020.11.06.370999 — genomics — Posted on 2020-11-06
3254 Whole genome sequencing for diagnosis of neurological repeat expansion disorders
Ibanez, K.; Polke, J.; Hagelstrom, T.; Dolzhenko, E.; Pasko, D.; Thomas, E.; Daugherty, L.; Kasperaviciute, D.; McDonagh, E. M.; Smith, K. R.; Rueda Martin, A.; Polychronopoulos, D.; Angus-Leppan, H.; Bhatia, K. P.; Davison, J. E.; Festenstein, R.; Fratta, P.; Giunti, P.; Howard, R.; Korlipara, L. V. P.; Laura, M.; McEntagart, M.; Menzies, L.; Morris, H.; Reilly, M. M.; Robinson, R.; Rosser, E.; Faravelli, F.; Schrag, A.; Schott, J. M.; Warner, T. T.; Wood, N. W.; Bourn, D.; Eggleton, K.; Labrum, R.; Twiss, P.; Abbs, S.; Santos, L.; Almheiri, G.; Sheikh, I.; Vandrovcova, J.; Patch, C.; Tavares
10.1101/2020.11.06.371716 — genomics — Posted on 2020-11-06
3257 The oxidative stress response and virulence of pathogenic Leptospira are controlled by the interplay of two peroxide stress regulators
Zavala-Alvarado, C.; Vincent, A. T.; Sismeiro, O.; Legendre, R.; Varet, H.; Bussotti, G.; Lorioux, C.; Coppee, J.-Y.; Veyrier, F. J.; Picardeau, M.; Benaroudj, N.
10.1101/2020.11.06.371039 — microbiology — Posted on 2020-11-06
3258 Rhinovirus reduces the severity of subsequent respiratory viral infections, which is associated with dampened inflammatory responses
Van Leuven, J. T.; Gonzalez, A. J.; Wixom, A. Q.; Clary, J. L.; Ridenhour, B. J.; Miller, C. R.; Miura, T. A.
10.1101/2020.11.06.371005 — microbiology — Posted on 2020-11-06
3259 Persistence of SARS-CoV-2 specific B- and T-cell responses in convalescent COVID-19 patients 6-8 months after the infection
Sherina, N.; Piralla, A.; Du, L.; Wan, H.; Kumagai-Braesh, M.; Andrell, J.; Braesch-Andersen, S.; Cassaniti, I.; Percivalle, E.; Sarasini, A.; Bergami, F.; Di Martino, R.; Colaneri, M.; Vecchia, M.; Sambo, M.; Zuccaro, V.; Bruno, R.; Oggionni, T.; Meloni, F.; Abolhassani, H.; Bertoglio, F.; Schubert, M.; Byrne-Steele, M.; Han, J.; Hust, M.; Xue, Y.; Hammarstrom, L.; Baldanti, F.; Marcotte, H.; Pan-Hammarstrom, Q.
10.1101/2020.11.06.371617 — immunology — Posted on 2020-11-06
3262 Genome-wide analysis of long noncoding RNAs, 24-nt siRNAs, DNA methylation and H3K27me3 marks in Brassica rapa and related species
Mehraj, H.; Shea, D. J.; Takahashi, S.; Miyaji, N.; Akter, A.; Seki, M.; Dennis, E. S.; Fujimoto, R.; Osabe, K.
10.1101/2020.11.06.370940 — plant biology — Posted on 2020-11-06
3264 The Genomic History of the Middle East
Almarri, M. A.; Haber, M.; Lootah, R. A.; Hallast, P.; Al Turki, S.; Martin, H. C.; Xue, Y.; Tyler-Smith, C.
10.1101/2020.10.18.342816 — genomics — Posted on 2020-11-06
3266 Badger territoriality maintained despite disturbance of major road construction
Gaughran, A.; Mullen, E.; MacWhite, T.; Maher, P.; Kelly, D. J.; Kelly, R.; Good, M.; Marples, N. M.
10.1101/2020.11.06.370957 — ecology — Posted on 2020-11-06
3267 Stem Cell Transplantation Rescued A Primary Open-Angle Glaucoma Mouse Model
Xiong, S.; Kumar, A.; Tian, S.; Taher, E.; Yang, E.; Kinchington, P. R.; Xia, X.; Du, Y.
10.1101/2020.02.04.934448 — cell biology — Posted on 2020-11-06
3268 Viral protein engagement of GBF1 induces host cell vulnerability through synthetic lethality
Navare, A. T.; Mast, F. D.; Olivier, J. P.; Bertomeu, T. D.; Carpp, L. N.; Kaushansky, A.; Coulombe-Huntington, J.; Neal, M.; Tyers, M.; Aitchison, J. D.
10.1101/2020.10.12.336487 — molecular biology — Posted on 2020-11-06
3270 Delta- and theta-band cortical tracking and phase-amplitude coupling to sung speech by infants
Attaheri, A.; Ni Choisdealbha, A.; Di Liberto, G.; Rocha, S.; Brusini, P.; Mead, N.; Olawole-Scott, H.; Boutris, P.; Gibbon, S.; Williams, I.; Grey, C.; Flanagan, S.; Goswami, U.
10.1101/2020.10.12.329326 — neuroscience — Posted on 2020-11-06
3271 Fine-mapping the consequences of site-specific glycan installation by shotgun scanning glycomutagenesis
Li, M.; Zheng, X.; Shanker, S.; Jaroentomeechai, T.; Kocer, I.; Byrne, J.; Cox, E. C.; Fu, Q.; Zhang, S.; Labonte, J. W.; Gray, J. J.; DeLisa, M. P.
10.1101/2020.06.28.176198 — synthetic biology — Posted on 2020-11-06
3273 Streamlining Data-Intensive Biology With Workflow Systems
Reiter, T.; Brooks, P. T.; Irber, L.; Joslin, S. E. K.; Reid, C. M.; Scott, C.; Brown, C. T.; Pierce, N. T.
10.1101/2020.06.30.178673 — bioinformatics — Posted on 2020-11-06
3274 Integration of genetic, transcriptomic, and clinical data provides insight into 16p11.2 and 22q11.2 CNV genes
Vysotskiy, M.; Zhong, X.; Miller-Fleming, T. W.; Zhou, D.; Autism Working Group of the Psychiatric Genomics Consortium, ; Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, ; Schizophrenia Working Group of the Psychiatric Genomics Consortium, ; Cox, N. J.; Weiss, L. A.
10.1101/2020.06.23.166181 — genetics — Posted on 2020-11-06
3276 Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs
He, S.; Wang, L.-H.; Liu, Y.; Li, Y.-Q.; Chen, H.-T.; Xu, J.-H.; Peng, W.; Lin, G.-W.; Wei, P.-P.; Li, B.; Xia, X.; Wang, D.; Bei, J.-X.; He, X.; Guo, Z.
10.1101/2020.03.18.996975 — cell biology — Posted on 2020-11-06
3277 Human Chr18: "Stakhanovite" Genes, Missing and uPE1 Proteins in Liver Tissue and HepG2 Cells
Krasnov, G. S.; Lisitsa, A. V.; Ponomarenko, E. A.; Radko, S. P.; Ptitsyn, K. G.; Shapovalova, V. V.; Timoshenko, O. S.; Khmeleva, S. A.; Kurbatov, L. K.; Kiseleva, Y. Y.; Ilgisonis, E. V.; Pyatnitskiy, M. A.; Poverennaya, E. V.; Kiseleva, O. I.; Vakhrushev, I. V.; Tsvetkova, A. V.; Buromski, I. V.; Markin, S. S.; Zgoda, V. G.; Archakov, A. I.
10.1101/2020.11.04.358739 — molecular biology — Posted on 2020-11-06
3278 Transcription and splicing dynamics during early Drosophila development
Prudencio, P.; Rebelo, K.; Savisaar, R.; Martinho, R. G.; Carmo-Fonseca, M.
10.1101/2020.11.05.367888 — molecular biology — Posted on 2020-11-06
3280 Phage recombination drives evolution of spore-forming Bacilli
Dragos, A.; B, P.; Hasan, Z.; Lenz-Strube, M.; Kempen, P. J.; Maroti, G.; Kaspar, C.; Bose, B.; Burton, B.; Bischofs, I. B.; Kovacs, A. T.
10.1101/2020.05.06.055103 — microbiology — Posted on 2020-11-06
3281 Impact of Rap-Phr system abundance on adaptation of Bacillus subtilis
Gallegos-Monterrosa, R.; Nordgaard Christensen, M.; Barchewitz, T.; Koppenhoefer, S.; Priyadarshini, B.; Balint, B.; Maroti, G.; Kempen, P. J.; Dragos, A.; Kovacs, A. T.
10.1101/2020.09.01.278184 — microbiology — Posted on 2020-11-06
3282 Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer's disease mouse model
Muraoka, S.; Jedrychowski, M. P.; Iwahara, N.; Abdullah, M.; Onos, K. D.; Keezer, K. J.; Hu, J.; Ikezu, S.; Howell, G. R.; Gygi, S. P.; Ikezu, T.
10.1101/2020.11.05.369728 — neuroscience — Posted on 2020-11-06
3283 A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
Vizioli, L.; Moeller, S.; Dowdle, L.; Akcakaya, M.; De Martino, F.; Yacoub, E.; Ugurbil, K.
10.1101/2020.11.04.368357 — neuroscience — Posted on 2020-11-06
3285 Cellular mRNA signals in human kidney tumors
Young, M. D.; Mitchell, T. J.; Custers, L. M.; Margaritis, T.; Morales, F.; Kwakwa, K.; Khabirova, E.; Kildisiute, G.; Oliver, T. R.; Krijger, R. R. d.; Heuvel-Eibrink, M. M. v. d.; Comitani, F.; Piapi, A.; Blanco, E. B.; Thevanesan, C.; Burke, C.; Prigmore, E.; Ambridge, K.; Roberts, K.; Braga, F. A. V.; Coorens, T. H.; Valle, I. D.; Wilbrey-Clark, A.; Mamanova, L.; Stewart, G. D.; Gnanapragasam, V. J.; Rampling, D.; Sebire, N.; Coleman, N.; Hook, L.; Warren, A.; Haniffa, M.; Kool, M.; Pfister, S. M.; Achermann, J. C.; He, X.; Barker, R. A.; Shlien, A.; Bayraktar, O. A.; Teichmann, S.; Holste
10.1101/2020.03.19.998815 — cancer biology — Posted on 2020-11-06
3286 Strengthening the BioCompute Standard by Crowdsourcing on PrecisionFDA
Stephens, S. H.; King, C. H.; Watford, S.; Patel, J.; Dean, D. A.; Koc, S.; Xiao, N.; Donaldson, E. F.; Thompson, E. E.; Purkayastha, A.; Mazumder, R.; Johanson, E.; Keeney, J.
10.1101/2020.11.02.365528 — bioinformatics — Posted on 2020-11-06
3288 Development of Optically-Controlled "Living Electrodes" with Long-Projecting Axon Tracts for a Synaptic Brain-Machine Interface
Adewole, D. O.; Struzyna, L. A.; Burrell, J. C.; Harris, J. P.; Nemes, A. D.; Petrov, D.; Kraft, R. H.; Chen, H. I.; Serruya, M. D.; Wolf, J. A.; Cullen, D. K.
10.1101/333526 — bioengineering — Posted on 2020-11-06
3289 H3K27me3-rich genomic regions can function as silencers to repress gene expression via chromatin interactions
Cai, Y.; Zhang, Y.; Loh, Y. P.; Tng, J. Q.; Lim, M. C.; Cao, Z.; Raju, A.; Aiden, E. L.; Li, S.; Manikandan, L.; Tergaonkar, V.; Tucker-Kellogg, G.; Fullwood, M. J.
10.1101/684712 — genomics — Posted on 2020-11-06
3293 Sclerostin depletion induces inflammation in the bone marrow of mice
Donham, C.; Chicana, B.; Robling, A. G.; Mohamed, A.; Elizaldi, S.; Chi, M.; Freeman, B.; Millan, A.; Murguesh, D.; Loots, G. G.; Manilay, J. O.
10.1101/2020.11.01.364158 — immunology — Posted on 2020-11-06
3294 TOLLIP resolves lipid-induced EIF2 signaling in alveolar macrophages for durable Mycobacterium tuberculosis protection.
Venkatasubramanian, S.; Plumlee, C.; Dill-McFarland, K.; Pearson, G.; Cohen, S. B.; Lietzke, A.; Hinderstein, S. A.; Pryor, R.; Soleimanpour, S. A.; Altman, M.; Urdahl, K. B.; Shah, J. A.
10.1101/2020.08.24.263624 — immunology — Posted on 2020-11-06
3296 Superior Colliculus to VTA pathway controls orienting response to conspecific stimuli.
Prevost-Solie, C.; Contestaile, A.; Espinosa, P.; Musardo, S.; Bariselli, S.; Huber, C.; Carleton, A.; Bellone, C.
10.1101/735340 — neuroscience — Posted on 2020-11-06
3298 Data-driven classification of spectral profiles reveals brain region-specific plasticity
Lubinus, C.; Orpella, J.; Keitel, A.; Gudi-Mindermann, H.; Engel, A. K.; Roeder, B.; Rimmele, J. M.
10.1101/782979 — neuroscience — Posted on 2020-11-06
3300 Sexually divergent cortical control of affective-autonomic integration
Wallace, T.; Schaeuble, D.; Pace, S. A.; Schackmuth, M. K.; Hentges, S. T.; Chicco, A. J.; Myers, B.
10.1101/2020.09.29.319210 — neuroscience — Posted on 2020-11-06
3301 NOise Reduction with DIstribution Corrected (NORDIC) PCA in dMRI with complex-valued parameter-free locally low-rank processing
Moeller, S.; Pishardy, P. K.; Ramanna, s.; Lenglet, C.; Wu, X.; Dowdle, L.; Yacoub, E.; Ugurbil, K.; Akcakaya, M.
10.1101/2020.08.25.267062 — neuroscience — Posted on 2020-11-06
3303 A longitudinal analysis of puberty-related cortical development
Vijayakumar, N.; Youssef, G.; Allen, N. B.; Anderson, V.; Efron, D.; Hazell, P.; Mundy, L.; Nicholson, J. M.; Patton, G.; Seal, M. L.; Simmons, J. G.; Whittle, S.; Silk, T.
10.1101/2020.11.05.370460 — neuroscience — Posted on 2020-11-06
3305 The APETALA2 transcription factor LsAP2 regulates seed shape in lettuce
Luo, C.; Wang, S.; Ning, K.; Chen, Z.; Wang, Y.; Yang, J.; Qi, M.; Wang, Q.
10.1101/2020.11.05.370684 — plant biology — Posted on 2020-11-06
3306 Complex population structure of the Atlantic puffin revealed by whole genome analyses
Kersten, O.; Star, B.; Leigh, D. M.; Anker-Nilssen, T.; Stroem, H.; Danielsen, J.; Descamps, S.; Erikstad, K. E.; Fitzsimmons, M. G.; Fort, J.; Hansen, E. S.; Harris, M. P.; Irestedt, M.; Kleven, O.; Mallory, M. L.; Jakobsen, K. S.; Boessenkool, S.
10.1101/2020.11.05.351874 — genomics — Posted on 2020-11-06
3308 In vivo proteomic mapping through GFP-directed proximity dependent biotin labelling in zebrafish
Xiong, Z.; Lo, H. P.; McMahon, K.-A.; Martel, N.; Jones, A.; Hill, M. M.; Parton, R. G.; Hall, T. E.
10.1101/2020.11.05.370585 — cell biology — Posted on 2020-11-06
3310 Progesterone specifically dampens disease-associated TH1- and TH17-related immune responses during T cell activation in vitro
Hellberg, S.; Raffetseder, J.; Rundquist, O.; Magnusson, R.; Papapavlou, G.; Jenmalm, M. C.; Ernerudh, J.; Gustafsson, M.
10.1101/2020.11.05.370700 — immunology — Posted on 2020-11-06
3313 EEG frequency tagging reveals neural entrainment to people moving in synchrony
Cracco, E.; Lee, H.; van Belle, G.; Quenon, L.; Haggard, P.; Rossion, B.; Orgs, G.
10.1101/2020.11.06.368118 — neuroscience — Posted on 2020-11-06
3314 Mitochondrial pathway polygenic risk scores are associated with Alzheimer's Disease
Paliwal, D.; McInerney, T. W.; Pa, J.; Swerdlow, R. H.; Easteal, S.; Andrews, S. J.
10.1101/2020.11.06.371286 — neuroscience — Posted on 2020-11-06
3317 NERO: A Biomedical Named-entity (Recognition) Ontology with a Large, Annotated Corpus Reveals Meaningful Associations Through Text Embedding
Wang, K.; Stevens, R.; Alachram, H.; Li, Y.; Soldatova, L.; King, R.; Ananiadou, S.; Li, M.; Christopoulou, F.; Ambite, J. L.; Garg, S.; Hermjakob, U.; Marcu, D.; Sheng, E.; Beissbarth, T.; Wingender, E.; Galstyan, A.; Gao, X.; Chambers, B.; Khomtchouk, B. B.; Evans, J. A.; Rzhetsky, A.
10.1101/2020.11.05.368969 — systems biology — Posted on 2020-11-06
3319 Activating Immune Recognition in Pancreatic Ductal Adenocarcinoma Using Autophagy Inhibition, MEK blockade and CD40 Agonism
Jiang, H.; Courau, T.; Lupin-Jimenez, L.; Borison, J.; Ritchie, A. J.; Mayer, A. T.; Krummel, M. F.; Collisson, E. A.
10.1101/2020.11.05.370569 — cancer biology — Posted on 2020-11-06
3320 ExTaxsI: an exploration tool of biodiversity molecular data
Agostinetto, G.; Sandionigi, A.; Chahed, A.; Brusati, A.; Parladori, E.; Balech, B.; Bruno, A.; Pescini, D.; Casiraghi, M.
10.1101/2020.11.05.369983 — bioinformatics — Posted on 2020-11-06
3321 emiRIT: A text-mining based resource for microRNA information
Roychowdhury, D.; Gupta, S.; Qin, X.; Arighi, C. N.; Vijay-Shanker, K.
10.1101/2020.11.05.370593 — bioinformatics — Posted on 2020-11-06
3322 Modeling CRISPR gene drives for suppression of invasive rodents
Champer, S. E.; Oakes, N.; Sharma, R.; Garcia-Diaz, P.; Champer, J.; Messer, P. W.
10.1101/2020.11.05.369942 — ecology — Posted on 2020-11-06
3323 A Mycobacterium tuberculosis effector protein attacks host innate immunity by acting as an unusual ubiquitinating enzyme
Wang, J.; Ge, P.; Lei, Z.; Qiang, L.; Chai, Q.; Zhang, Y.; Lu, Z.; Zhao, D.; Li, B.; Su, J.; Peng, R.; Pang, Y.; Shi, Y.; Gao, G. F.; Qiu, X.-B.; Liu, C. H.
10.1101/2020.11.05.370551 — microbiology — Posted on 2020-11-06
3324 Arenavirus nucleoprotein localizes to mitochondria
Baggio, F.; Hetzel, U.; Nufer, L.; Kipar, A.; Hepojoki, J. M.
10.1101/2020.11.06.370825 — microbiology — Posted on 2020-11-06
3325 Lipidomic Profiling Reveals an Age-Related Deficiency of Skeletal Muscle Proresolving Mediators that Contributes to Maladaptive Tissue Remodeling
Markworth, J. F.; Brown, L. A.; Lim, E.; Castor-Macias, J. A.; Larouche, J.; Macpherson, P. C. D.; Davis, C.; Aguilar, C. A.; Maddipati, K. R.; Brooks, S. V.
10.1101/2020.11.05.370056 — immunology — Posted on 2020-11-06
3337 A single QTL with large effect is associated with female functional virginity in an asexual parasitoid wasp
Ma, W.-J.; Pannebakker, B. A.; Li, X.; Geuverink, E.; Anvar, S. Y.; Veltsos, P.; Schwander, T.; van de Zande, L.; Beukeboom, L. W.
10.1101/2020.11.05.370544 — evolutionary biology — Posted on 2020-11-06
3338 Causal inference gates corticostriatal learning
Dorfman, H. M.; Tomov, M. S.; Cheung, B.; Clarke, D.; Gershman, S. J.; Hughes, B. L.
10.1101/2020.11.05.369793 — neuroscience — Posted on 2020-11-06
3340 Nodosome inhibition as a novel broad-spectrum antiviral strategy against arboviruses and SARS-CoV-2
Limonta, D.; Dyna-Dagman, L.; Branton, W.; Makio, T.; Wozniak, R. W.; Power, C.; Hobman, T. C.
10.1101/2020.11.05.370767 — microbiology — Posted on 2020-11-06
3341 Potent SARS-CoV-2 neutralizing antibodies selected from a human antibody library constructed decades ago
Qiang, M.; Ma, P.; Li, Y.; Liu, H.; Harding, A.; Min, C.; Liu, L.; Yuan, M.; Ji, Q.; Tao, P.; Shi, X.; Li, Z.; Wang, F.; Zhang, Y.; Wu, N. C.; Lee, C.-C. D.; Zhu, X.; Gilbert-Jaramillo, J.; Saxena, A.; Huang, X.; Wang, H.; James, W.; Dwek, R. A.; Wilson, I. A.; Yang, G.; Lerner, R. A.
10.1101/2020.11.06.370676 — microbiology — Posted on 2020-11-06
3343 Flagellin from Pseudomonas aeruginosa modulates SARS-CoV-2 infectivity in CF airway epithelial cells by increasing TMPRSS2 expression
Ruffin, M.; Bigot, J.; Calmel, C.; Mercier, J.; Pizzorno, A.; Rosa-Calatrava, M.; Corvol, H.; Balloy, V.; Terrier, O.; Guillot, L.
10.1101/2020.08.24.264564 — pathology — Posted on 2020-11-06
3345 Acrylamide Fragment Inhibitors that Induce Unprecedented Conformational Distortions in Enterovirus 71 3C and SARS-CoV-2 Main Protease
Qin, B.; Craven, G. B.; Hou, P.; Lu, X.; Child, E. S.; Morgan, R. M. L.; Armstrong, A.; Mann, D. J.; Cui, S.
10.1101/2020.11.06.370916 — biochemistry — Posted on 2020-11-06
3348 Tissue Level Profiling of SARS-CoV-2 antivirals in mice to predict their effects: comparing Remdesivir's active metabolite GS-441 524 vs. the clinically failed Hydroxychloroquine
Scherf-Clavel, O.; Kaczmarek, E.; Kinzig, M.; Friedl, B.; Feja, M.; Hoehl, R.; Nau, R.; Holzgrabe, U.; Gernert, M.; Richter, F.; Soergel, F.
10.1101/2020.09.16.299537 — systems biology — Posted on 2020-11-06
3350 NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
Marques, C.; Unterkircher, T.; Kroon, P.; Izzo, A.; Dramaretska, Y.; Kling, E.; Oldrini, B.; Schnell, O.; Nelander, S.; Wagner, E. F.; Bakiri, L.; Gargiulo, G.; Carro, M. S.; Squatrito, M.
10.1101/834531 — cancer biology — Posted on 2020-11-06
3351 The fluid dynamics of collective vortex structures of plant-animal worms
Fortune, G. T.; Worley, A.; Sendova-Franks, A.; Franks, N.; Leptos, K. C.; Lauga, E.; Goldstein, R. E.
10.1101/2020.11.04.366658 — biophysics — Posted on 2020-11-06
3352 periscope: Sub-Genomic RNA Identification in SARS-CoV-2 Genomic Sequencing Data
Parker, M. D.; Lindsey, B. B.; Leary, S.; Gaudieri, S.; Chopra, A.; Wyles, M.; Angyal, A.; Green, L. R.; Parsons, P.; Tucker, R. M.; Brown, R.; Groves, D.; Johnson, K.; Carrilero, L.; Heffer, J.; Partridge, D.; Evans, C.; Razza, M.; Keeley, A. J.; Smith, N.; Filipe, A. D. S.; Shepherd, J. G.; Davis, C.; Bennett, S.; Kohl, A.; Aranday-Cortes, E.; Tong, L.; Nichols, J.; Thomson, E. C.; The COVID-19 Genomics UK (COG-UK) consortium, ; Wang, D.; Mallal, S.; de Silva, T. I.
10.1101/2020.07.01.181867 — bioinformatics — Posted on 2020-11-06
3353 Epigenetic transgenerational effects on RNAi in Arabidopsis
Hu, Q.; Ailhas, J.; Blevins, T.; Klahre, U.; Vazquez, F.; Mette, M. F.; Meins, F.
10.1101/2020.04.05.026641 — plant biology — Posted on 2020-11-06
3358 SGLT2 inhibition by intraperitoneal dapagliflozin mitigates peritoneal fibrosis and ultrafiltration failure in a mouse model of chronic peritoneal exposure to high-glucose dialysate
Balzer, M. S.; Rong, S.; Nordlohne, J.; Zemtsovski, J. D.; Schmidt, S.; Stapel, B.; Bartosova, M.; von Vietinghoff, S.; Haller, H.; Schmitt, C. P.; Shushakova, N.
10.1101/2020.11.04.366724 — molecular biology — Posted on 2020-11-06
3361 Enrichment of neurodegenerative microglia signature in brain-derived extracellular vesicles isolated from Alzheimer's disease mouse model
Muraoka, S.; Jedrychowski, M. P.; Iwahara, N.; Abdullah, M.; Onos, K. D.; Keezer, K. J.; Hu, J.; Ikezu, S.; Howell, G. R.; Gygi, S. P.; Ikezu, T.
10.1101/2020.11.05.369728 — neuroscience — Posted on 2020-11-06
3362 Gene-corrected Parkinson's disease neurons show the A30P alpha-synuclein point mutation leads to reduced neuronal branching and function
Barbuti, P. A.; Santos, B. F.; Antony, P. M.; Massart, F.; Cruciani, G.; Dording, C. M.; Pavelka, L.; Kwon, Y.-J.; Krueger, R. A.
10.1101/2020.11.05.369389 — neuroscience — Posted on 2020-11-06
3364 Sexual selection drives maladaptive learning under climate warming
Holveck, M.-J.; Muller, D.; Visser, B.; Pels, C.; Timmermans, A.; Colonval, L.; Jan, F.; Crucifix, M.; Nieberding, C.
10.1101/2020.11.05.369561 — evolutionary biology — Posted on 2020-11-06
3369 Single-cell RNA-seq uncovers shared and distinct axes of variation in dorsal LGN neurons in mice, non-human primates and humans
Bakken, T. E.; van Velthoven, C. T. J.; Menon, V.; Hodge, R. D.; Yao, Z.; Nguyen, T. N.; Graybuck, L. T.; Horwitz, G. D.; Bertagnolli, D.; Goldy, J.; Garren, E.; Parry, S.; Casper, T.; Shehata, S. I.; Barkan, E. R.; Szafer, A.; Levi, B. P.; Dee, N.; Smith, K. A.; Sunkin, S. M.; Bernard, A.; Phillips, J. W.; Hawrylycz, M.; Koch, C.; Murphy, G.; Lein, E.; Zeng, H.; Tasic, B.
10.1101/2020.11.05.367482 — neuroscience — Posted on 2020-11-06
3370 Breaking the limit of 3D fluorescence microscopy by dual-stage-processing network
Zhang, H.; Zhao, Y.; Fang, C.; Li, G.; Zhang, M.; Zhang, Y.; Fei, P.
10.1101/435040 — biophysics — Posted on 2020-11-06
3374 Mass spectrometry and CLIP-seq analysis reveal BCL11b interactions with RNA processing pathways
Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; WALLET, C.; DAOUAD, F.; Van Lint, C.; SCHWARTZ, C.; ROHR, O.
10.1101/2020.11.05.369959 — developmental biology — Posted on 2020-11-06
3377 Ultra-precise quantification of mRNA targets across a broad dynamic range with nanoreactor beads
Loncarevic, I. F.; Toepfer, S.; Hubold, S.; Klingner, S.; Kanitz, L.; Ellinger, T.; Steinmetzer, K.; Ernst, T.; Hochhaus, A.; Ermantraut, E.
10.1101/2020.11.05.369637 — molecular biology — Posted on 2020-11-05
3378 Innate fear responses are reflected in the blood epigenome of rhesus macaques.
Bravo-Rivera, H.; Lardenoije, R.; Merced, D.; Mas-Rivera, A.; Ayala, J. E.; Goncalves, J. P.; Seligowski, A. V.; Jovanovic, T.; Ressler, K. J.; Klengel, T.; Quirk, G. J.
10.1101/2020.11.05.369538 — neuroscience — Posted on 2020-11-05
3379 AMPK Modulates Associative Learning via Neuronal Mitochondrial Fusion in C. elegans
Escoubas, C. C.; Laversenne, V.; Tabakovic, E.; Weir, H. J.; Clark, N.; Mair, W. B.
10.1101/2020.11.05.370031 — neuroscience — Posted on 2020-11-05
3381 Lipidation of a bacterial effector is critical for bacterial evasion of host-defense
Cattelan, N.; Yu, H.; Przybyszewska, K.; Colamarino, R. A.; Baldassarre, M.; Spano, S.
10.1101/2020.11.05.369652 — microbiology — Posted on 2020-11-05
3383 Synergy and allostery in ligand binding by HIV-1 Nef
Aldehaiman, A.; Momin, A. A.; Restouin, A.; Wang, L.; Shi, X.; Aljedani, S.; Opi, S.; Lugari, A.; Hameed, U. F. S.; Ponchon, L.; Morelli, X.; Huang, M.; Dumas, C.; Collette, Y.; Arold, S. T.
10.1101/2020.11.05.369645 — biophysics — Posted on 2020-11-05
3386 CRISPRIdentify: Identification of CRISPR arrays using machine learning approach
Mitrofanov, A.; Alkhnbashi, O. S.; Shmakov, S. A.; Makarova, K. S.; Koonin, E. V.; Backofen, R.
10.1101/2020.11.05.369512 — bioinformatics — Posted on 2020-11-05
3387 A new duck genome reveals conserved and convergently evolved chromosome architectures of birds and mammals
Li, J.; Zhang, J.; Liu, J.; Zhou, Y.; Cai, C.; Xu, L.; Dai, X.; Feng, S.; Guo, C.; Rao, J.; Wei, K.; Jarvis, E.; Jiang, Y.; Zhou, Z.; Zhang, G.; Zhou, Q.
10.1101/2020.11.04.368910 — genomics — Posted on 2020-11-05
3388 The recombination landscape and multiple QTL mapping in a Solanum tuberosum cv. 'Atlantic'-derived F1 population
Da Silva Pereira, G.; Mollinari, M.; Schumann, M. J.; Clough, M. E.; Zeng, Z.-B.; Yencho, C.
10.1101/2020.08.24.265397 — genetics — Posted on 2020-11-05
3391 Bromodomain protein inhibition protects β-cells from cytokine-induced death and dysfunction via antagonism of NF-κB pathway.
Negi, V.; Lee, J.; Liu, R.; Perez-Garcia, E. M.; Li, F.; Jagannathan, R.; Yang, P.; Bottino, R.; Ma, K.; Moulik, M.; Yechoor, V.
10.1101/2020.11.05.363408 — molecular biology — Posted on 2020-11-05
3392 AXTEX-4D™: A Novel 3D ex vivo platform for preclinical investigations of immunotherapy agents
Baru, A.; Sharma, S.; Das Purkayastha, B. P.; Khan, S.; Mazumder, S.; Gupta, R.; Kundu, P. K.; Arora, N. M.
10.1101/2020.11.05.369751 — immunology — Posted on 2020-11-05
3394 The human ApoE4 variant reduces functional recovery and neuronal sprouting after incomplete spinal cord injury in male mice
Toro, C. A.; Hansen, J.; Siddiq, M. M.; Johnson, K.; Zhao, W.; Azulai, D.; Das, D. K.; Bauman, W.; Sebra, R.; Cai, D.; Iyengar, R.; Cardozo, C. P.
10.1101/2020.11.05.369900 — neuroscience — Posted on 2020-11-05
3397 Microbiome meta-analysis and cross-disease comparison enabled by the SIAMCAT machine-learning toolbox
Wirbel, J.; Zych, K.; Essex, M.; Karcher, N.; Kartal, E.; Salazar, G.; Bork, P.; Sunagawa, S.; Zeller, G.
10.1101/2020.02.06.931808 — bioinformatics — Posted on 2020-11-05
3399 iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome
Kosanke, M.; Davenport, C.; Szepes, M.; Wiehlmann, L.; Kohrn, T.; Dorda, M.; Gruber, J.; Menge, K.; Sievert, M.; Melchert, A.; Gruh, I.; Martin, U.
10.1101/2020.11.05.369694 — genomics — Posted on 2020-11-05
3401 Ecological dynamics of the almond floral microbiome in relation to crop management and pollination
Schaeffer, R. N.; Crowder, D. W.; Illan, J. G.; Beck, J. J.; Fukami, T.; Williams, N. M.; Vannette, R. L.
10.1101/2020.11.05.367003 — ecology — Posted on 2020-11-05
3402 Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List
Marsh, S. M. E.; Hoffmann, M.; Burgess, N. D.; Brooks, T. M.; Challender, D. W. S.; Cremona, P. J.; Hilton-Taylor, C.; Lafaye de Micheaux, F.; Lichtenstein, G.; Roe, D.; Bohm, M.
10.1101/2020.11.04.367763 — ecology — Posted on 2020-11-05
3403 Mass spectrometry and CLIP-seq analysis reveal BCL11b interactions with RNA processing pathways
Sobhy, H.; De Rovere, M.; Ait-Ammar, A.; SCHWARTZ, C.; Van Lint, C.; ROHR, O.; WALLET, C.; DAOUAD, F.
10.1101/2020.11.05.369959 — developmental biology — Posted on 2020-11-05
3404 Liver FoxO1 overexpression is positively associated with the degree of liver injury in cirrhotic patients
Fernandez-Galan, E.; Sandalinas, S.; Morales-Romero, B.; Macias, L.; Pauta, M.; Ribera, J.; Casals, G.; Boix, L.; Bruix, J.; Jimenez, W.; Morales-Ruiz, M.
10.1101/2020.11.05.369504 — cell biology — Posted on 2020-11-05
3406 Metabolomic investigation of the pseudouridimycin producer, a prolific streptomycete
Iorio, M.; Davatgarbenam, S.; Serina, S.; Criscenzo, P.; Zdouc, M. M.; Simone, M.; Maffioli, S. I.; Ebright, R. H.; Donadio, S.; Sosio, M.
10.1101/2020.11.05.369249 — microbiology — Posted on 2020-11-05
3408 SLAMF7 engagement super-activates macrophages in acute and chronic inflammation
Simmons, D. P.; Nguyen, H.; Gomez-Rivas, E.; Jeong, Y.; Chen, A. F.; Lange, J. K.; Dyer, G. S.; Blazar, P.; Earp, B. E.; RA/SLE Network, A. M. P.; Rao, D. A.; Kim, E. Y.; Brenner, M. B.
10.1101/2020.11.05.368647 — immunology — Posted on 2020-11-05
3412 HERC1 regulates breast cancer cells migration and invasion
Rossi, F. A.; Calvo Roitberg, E. H.; Enrique Steinberg, J. H.; Joshi, M.; Espinosa, J. M.; Rossi, M.
10.1101/2020.11.05.369975 — cancer biology — Posted on 2020-11-05
3414 Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins
Belan, O.; Barroso, C.; Kaczmarczyk, A.; Anand, R.; Federico, S.; O'Reilly, N.; Newton, M. D.; Maeots, E.; Enchev, R. I.; Martinez-Perez, E.; Rueda, D. S.; Boulton, S. J.
10.1101/2020.11.05.369629 — biophysics — Posted on 2020-11-05
3417 RatsPub: a webservice aided by deep learning to mine PubMed for addiction-related genes
Gunturkun, M. H.; Flashner, E.; Wang, T.; Mulligan, M. K.; Williams, R. W.; Prins, P.; Chen, H.
10.1101/2020.09.17.297358 — bioinformatics — Posted on 2020-11-05
3420 Complete and haplotype-specific sequence assembly of segmental duplication-mediated genome rearrangements using CRISPR-targeted ultra-long read sequencing (CTLR-Seq)
Zhou, B.; Shin, G.; Greer, S. U.; Vervoort, L.; Huang, Y.; Pattni, R.; Ho, M.; Wong, W. H.; Vermeesch, J. R.; Ji, H.; Urban, A. E.
10.1101/2020.10.23.349621 — genomics — Posted on 2020-11-05
3424 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dilmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-05
3428 Suppressing STAT3 activity protects the endothelial barrier from VEGF-mediated vascular permeability
Wang, L.; Astone, M.; Alam, S. K.; Zhu, Z.; Pei, W.; Frank, D. A.; Burgess, S. M.; Hoeppner, L. H.
10.1101/2020.10.27.358374 — molecular biology — Posted on 2020-11-05
3430 SARS-CoV-2 Assembly and Egress Pathway Revealed by Correlative Multi-modal Multi-scale Cryo-imaging
Mendonca, L.; Howe, A.; Gilchrist, J. B.; Sun, D.; Knight, M.; Zanetti-Domingues, L. C.; Bateman, B.; Krebs, A.-S.; Chen, L.; Radecke, J.; Sheng, Y.; Li, V. D.; Ni, T.; Kounatidis, I.; Koronfel, M. A.; Szynkiewicz, M.; Harkiolaki, M.; Martin-Fernandez, M. L.; James, W.; Zhang, P.
10.1101/2020.11.05.370239 — microbiology — Posted on 2020-11-05
3431 Immunocompetent Mouse Model for Crimean-Congo Hemorrhagic Fever Virus
Hawman, D. W.; Meade-White, K.; Leventhal, S.; Feldmann, F.; Okumura, A.; Smith, B.; Scott, D.; Feldmann, H.
10.1101/2020.11.05.369520 — immunology — Posted on 2020-11-05
3434 Cryo-EM structure of a proton-activated chloride channel TMEM206
Deng, Z.; Zhao, Y.; Feng, J.; Zhang, J.; Zhao, H.; Rau, M. J.; Fitzpatrick, J.; Hu, H.; Yuan, P.
10.1101/2020.11.05.369835 — biophysics — Posted on 2020-11-05
3437 A Fast Lysine Cross-linker DOPA Enables Mass Spectrometry Analyses of Protein Unfolding and Weak Protein-protein Interactions
Wang, J.-H.; Tang, Y.-L.; Jain, R.; Xiao, F.; Gong, Z.; Zhou, Y.; Tan, D.; Li, Q.; Dong, X.; Liu, S.-Q.; Tang, C.; Huang, N.; Ye, K.; Dong, M.-Q.; Lei, X.
10.1101/2020.11.05.369280 — biochemistry — Posted on 2020-11-05
3438 Identification of blood autosomal cis-expression quantitative trait methylation (cis-eQTMs) in children
Ruiz-Arenas, C.; Hernandez-Ferrer, C.; Vives-Usano, M.; Mari, S.; Quintela, I.; Mason, D.; Cadiou, S.; Casas, M.; Andrusaityte, S.; Gutzkow, K. B.; Vafeiadi, M.; Wright, J.; Lepeule, J.; Grazuleviciene, R.; Chatzi, L.; Carracedo, a.; Estivill, X.; Marti, E.; Escaramis, G.; Vrijheid, M.; Gonzalez, J. R.; Bustamante, M.
10.1101/2020.11.05.368076 — genomics — Posted on 2020-11-05
3443 Deletion of Crtc1 leads to hippocampal neuroenergetic impairments associated with depressive-like behavior
Cherix, A.; Poitry-Yamate, C.; Lanz, B.; Zanoletti, O.; Grosse, J.; Sandi, C.; Gruetter, R.; Cardinaux, J.-R.
10.1101/2020.11.05.370221 — neuroscience — Posted on 2020-11-05
3444 Non-lesioned subcortical brain volumes are associated with post-stroke sensorimotor behavior across 28 cohorts worldwide: An ENIGMA Stroke Recovery study
Liew, S.-L.; Zavaliangos-Petropulu, A.; Schweighofer, N.; Jahanshad, N.; Lang, C. E.; Lohse, K. R.; Banaj, N.; Barisano, G.; Baugh, L. A.; Bhattacharya, A. K.; Bigjahan, B.; Borich, M. R.; Boyd, L. A.; Brodtmann, A.; Buetefisch, C. M.; Byblow, W. D.; Cassidy, J. M.; Ciullo, V.; Conforto, A. B.; Craddock, R. C.; Dula, A. N.; Egorova, N.; Feng, W.; Fercho, K. A.; Gregory, C. M.; Hanlon, C. A.; Hayward, K. S.; Holguin, J. A.; Hordacre, B.; Hwang, D. H.; Kautz, S. A.; Khlif, M. S.; Kim, B.; Kuceyeski, A.; Liu, J.; Lin, D.; Lotze, M.; Kim, H.; MacIntosh, B. J.; Margetis, J. L.; Mohamed, F. B.; Nord
10.1101/2020.11.04.366856 — neuroscience — Posted on 2020-11-05
3447 Interrogation of SLFN11 in pediatric sarcomas uncovers an unexpected biological role and a novel therapeutic approach to overcoming resistance to replicative stress
Gartrell, J.; Mellado-Lagarde, M.; Martinez, N.; Clay, M.; Bahrami, A.; Sahr, N.; Sykes, A.; Blankenship, K.; Hoffmann, L.; Xie, J.; Cho, H. P.; Twarog, N.; Connelly, M.; Yan, K.-K.; Yu, J.; Porter, S. N.; Pruett-Miller, S. M.; Neale, G.; Tinkle, C.; Federico, S.; Stewart, E.; Shelat, A.
10.1101/2020.11.05.370155 — cancer biology — Posted on 2020-11-05
3448 Mechanistic inferences from analysis of measurements of protein phase transitions in live cells
Posey, A. E.; Ruff, K. M.; Lalmansingh, J. M.; Kandola, T. S.; Lange, J. J.; Halfmann, R.; Pappu, R. V.
10.1101/2020.11.04.369017 — biophysics — Posted on 2020-11-05
3449 The fluid dynamics of collective vortex structures of plant-animal worms
Fortune, G. T.; Worley, A.; Sendova-Franks, A.; Franks, N.; Leptos, K. C.; Goldstein, R. E.
10.1101/2020.11.04.366658 — biophysics — Posted on 2020-11-05
3451 Microbiome data enhances predictive models of lung function in people with cystic fibrosis
Zhao, C. Y.; Hao, Y.; Wang, Y.; Varga, J. J.; Stecenko, A. A.; Goldberg, J. B.; Brown, S. P.
10.1101/656066 — bioinformatics — Posted on 2020-11-05
3452 Integrated Analysis of Cell Shape and Movement in Moving Frame
Heryanto, Y. D.; Cheng, C.-Y.; Uchida, Y.; Mimura, K.; Ishii, M.; Yamada, R.
10.1101/2020.11.04.369033 — bioinformatics — Posted on 2020-11-05
3456 Age and diet shape the genetic architecture of body weight in Diversity Outbred mice
Wright, K. M.; Deighan, A.; Francesco, A. D.; Freund, A.; Jojic, V.; Churchill, G. A.; Raj, A.
10.1101/2020.11.04.364398 — genetics — Posted on 2020-11-05
3458 Streamlined and quantitative detection of chimerism in mouse tissue using digital PCR
Suchy, F. P.; Nishimura, T.; Wilkinson, A. C.; Higuchi, M.; Bhadury, J.; Nakauchi, H.
10.1101/2020.11.04.368944 — genetics — Posted on 2020-11-05
3459 Obligate cross-feeding expands the metabolic niche of bacteria
Ona, L.; Giri, S.; Avermann, N.; Kreienbaum, M.; Thormann, K.; Kost, C.
10.1101/2020.11.04.368415 — evolutionary biology — Posted on 2020-11-05
3462 Transcription and splicing dynamics during early Drosophila development
Prudencio, P.; Rebelo, K.; Savisaar, R.; Martinho, R. G.; Carmo-Fonseca, M.
10.1101/2020.11.05.367888 — molecular biology — Posted on 2020-11-05
3465 High fidelity electrophysiological, morphological, and transcriptomic cell characterization using a refined Patch-seq protocol
Lee, B. R.; Budzillo, A.; Hadley, K.; Miller, J. A.; Jarsky, T.; Baker, K.; Hill, D.; Kim, L.; Mann, R.; Ng, L.; Oldre, A.; Rajanbabu, R.; Trinh, J.; Braun, T.; Dalley, R.; Gouwens, N. W.; Kim, T. K.; Smith, K.; Soler-Llavina, G.; Sorensen, S.; Tasic, B.; Ting, J. T.; Zeng, H.; Murphy, G.; Berg, J.
10.1101/2020.11.04.369082 — neuroscience — Posted on 2020-11-05
3467 Landmark-Centered Coding in Frontal Cortex Visual Responses
Schuetz, A.; Bharmauria, V.; Yan, X.; Wang, H.; Bremmer, F.; Crawford, J. D.
10.1101/2020.11.04.368308 — neuroscience — Posted on 2020-11-05
3468 A Paradigm Change in Functional Brain Mapping: Suppressing the Thermal Noise in fMRI
Vizioli, L.; Moeller, S.; Dowdle, L.; Akcakaya, M.; De Martino, F.; Yacoub, E.; Ugurbil, K.
10.1101/2020.11.04.368357 — neuroscience — Posted on 2020-11-05
3471 Numerical Instabilities in Analytical Pipelines Lead to Large and Meaningful Variability in Brain Networks
Kiar, G.; Chatelain, Y.; de Oliveira Castro, P.; Petit, E.; Rokem, A.; Varoquaux, G.; Misic, B.; Evans, A. C.; Glatard, T.
10.1101/2020.10.15.341495 — neuroscience — Posted on 2020-11-05
3476 Performance of deep learning restoration methods for the extraction of particle dynamics in noisy microscopy image sequences
Kefer, P.; Iqbal, F.; Locatelli, M.; Lawrimor, J.; Zhang, M.; Bloom, K.; Bonin, K.; Vidi, P.-A.; Liu, J.
10.1101/2020.11.04.368928 — biophysics — Posted on 2020-11-05
3483 Scaling up biodiversity ecosystem functioning relationships: the role of environmental variability in space and time
Thompson, P. L.; Kefi, S.; Zelnik, Y. R.; Dee, L. E.; Wang, S.; de Mazancourt, C.; Loreau, M.; Gonzalez, A.
10.1101/2020.11.04.367250 — ecology — Posted on 2020-11-05
3486 Cytokinin inhibits fungal development and virulence by targeting cellular trafficking
Gupta, R.; Pizarro, L.; Anand, G.; Laor, D.; Kovetz, N.; Yehuda, T.; Gazit, E.; Bar, M.
10.1101/2020.11.04.369215 — microbiology — Posted on 2020-11-05
3488 Aberrant peripheral immune responses in acute Kawasaki disease with single-cell sequencing
Wang, Z.; Xie, L.; Song, S.; Chen, L.; Li, G.; Liu, J.; Xiao, T.; Zhang, H.; Huang, Y.; Ding, G.; Li, Y.; Huang, M.
10.1101/2020.11.05.369348 — immunology — Posted on 2020-11-05
3489 Synchronous and opponent thermosensors use flexible cross-inhibition to orchestrate thermal homeostasis
Hernandez-Nunez, L.; Chen, A.; Budelli, G.; Richter, V.; Rist, A.; Thum, A. S.; Klein, M.; Garrity, P. A.; Samuel, A. D. T.
10.1101/2020.07.09.196428 — neuroscience — Posted on 2020-11-05
3492 Tracking tau fibrillogenesis and consequent primary phagocytosis of neurons mediated by microglia in a living tauopathy model
Takuwa, H.; Orihara, A.; Takado, Y.; Shimojo, M.; Ishikawa, A.; Takahash, M.; Barron, A. M.; Ono, M.; Maeda, J.; Masamoto, K.; Akatsu, H.; Tolkovsky, A. M.; Ji, B.; Tomita, Y.; Ito, H.; Zhang, M.-R.; Goedert, M.; Spillantini, M. G.; Lee, V. M.-Y.; Trojanowski, J. Q.; Maehara, T.; Suhara, T.; Sahara, N.; Higuchi, M.
10.1101/2020.11.04.368977 — neuroscience — Posted on 2020-11-05
3495 Challenges in Undergraduate Synthetic Biology Training: Insights from a Canadian iGEM Student Perspective
Diep, P.; Boucinha, A.; Yeung, B.-r. A.; Kell, B.; Chen, X.; Tsyplenkov, D.; Serra, D.; Escobar, A.; Gnanapragasam, A.; Emond, C. A.; Sajtovich, V. A.; Mahadevan, R.; Kilkenny, D. M.; Gini-Newman, G.; Kaern, M.; Ingalls, B.
10.1101/2020.11.04.365999 — scientific communication and education — Posted on 2020-11-05
3496 Regulation of touch dependant de novo root regeneration in Arabidopsis
Shanmukhan, A. P.; Mathew, M. M.; Aiyaz, M.; Kareem, A.; Radhakrishnan, D.; Prasad, K.
10.1101/2020.11.04.367714 — plant biology — Posted on 2020-11-05
3498 Structural insights on the substrate-binding proteins of the Mycobacterium tuberculosis mammalian-cell-entry (Mce) 1 and 4 complexes
Asthana, P.; Singh, D.; Pedersen, J. S.; Hynönen, M. J.; Sulu, R.; Murthy, A. V.; Laitaoja, M.; Jänis, J.; W. Riley, L.; Venkatesan, R.
10.1101/2020.09.29.317909 — biophysics — Posted on 2020-11-05
3501 Phosphonate production by marine microbes: exploring new sources and potential function
Acker, M.; Hogle, S. L.; Berube, P. M.; Hackl, T.; Stepanauskas, R. M.; Chisholm, S. W.; Repeta, D. J.
10.1101/2020.11.04.368217 — biochemistry — Posted on 2020-11-05
3502 Revealing the evolutionary history of a reticulate polyploid complex in the genus Isoëtes
Suissa, J. S.; Kinosian, S. P.; Schafran, P. W.; Bolin, J. F.; Taylor, W. C.; Zimmer, E.
10.1101/2020.11.04.363374 — evolutionary biology — Posted on 2020-11-05
3504 High-throughput CRISPR screens to dissect macrophage-Shigella interactions
Lai, Y.; Cui, L.; Babunovic, G. H.; Fortune, S. M.; Doench, J. G.; Lu, T. K.
10.1101/2020.04.25.061671 — microbiology — Posted on 2020-11-05
3505 Hippocampal subfields integrate information about past temporal and cognitive contexts
Dimsdale-Zucker, H. R.; Montchal, M. E.; Reagh, Z. M.; Wang, S.-F.; Libby, L. A.; Ranganath, C. R.
10.1101/766311 — neuroscience — Posted on 2020-11-05
3507 Robust Inference of Kinase Activity using Functional Networks
Yilmaz, S.; Ayati, M.; Schlatzer, D.; Cicek, A. E.; Chance, M.; Koyuturk, M.
10.1101/2020.05.01.062802 — systems biology — Posted on 2020-11-05
3509 Chromatin-accessibility estimation of single-cell ATAC data
Li, Z.; Kuppe, C.; Ziegler, S.; Cheng, M.; Kabgani, N.; Menzel, S.; Zenke, M.; Kramann, R.; Costa, I. G.
10.1101/865931 — bioinformatics — Posted on 2020-11-05
3510 Rapid High Throughput Whole Genome Sequencing of SARS-CoV-2 by using One-step RT-PCR Amplification with Integrated Microfluidic System and Next-Gen Sequencing
Hang, J.; Li, T.; Chung, H. K.; Pireku, P. K.; Beitzel, B.; Sanborn, M. A.; Tang, C.; Hammer, R.; Ritter, D. G.; Wan, X.-F.; Maljkovic Berry, I.
10.1101/2020.11.04.369165 — molecular biology — Posted on 2020-11-05
3511 Human Identical Sequences of SARS-CoV-2 Promote Clinical Progression of COVID-19 by Upregulating Hyaluronan via NamiRNA-Enhancer Network
Li, W.; Yang, S.; Xu, P.; Zhang, D.; Tong, Y.; Chen, L.; Jia, B.; Li, A.; Ru, D.; Zhang, B.; Liu, M.; Lian, C.; Chen, C.; Fu, W.; Yuan, S.; Ren, X.; Liang, Y.; Yang, Z.; Li, W.; Wang, S.; Zhang, X.; Lu, H.; Xu, J.; Wang, H.; Yu, W.
10.1101/2020.11.04.361576 — molecular biology — Posted on 2020-11-05
3512 The circulating SARS-CoV-2 spike variant N439K maintains fitness while evading antibody-mediated immunity
Thomson, E. C.; Rosen, L. E.; Shepherd, J. G.; Spreafico, R.; da Silva Filipe, A.; Wojcechowskyj, J. A.; Davis, C.; Piccoli, L.; Pascall, D. J.; Dillen, J.; Lytras, S.; Czudnochowski, N.; Shah, R.; Meury, M.; Jesudason, N.; De Marco, A.; Li, K.; Bassi, J.; O'Toole, A.; Pinto, D.; Colquhoun, R. M.; Culap, K.; Jackson, B.; Zatta, F.; Rambaut, A.; Jaconi, S.; Sreenu, V. B.; Nix, J.; Jarrett, R. F.; Beltramello, M.; Nomikou, K.; Pizzuto, M.; Tong, L.; Cameroni, E.; Johnson, N.; Wickenhagen, A.; Ceschi, A.; Mair, D.; Ferrari, P.; Smollett, K.; Sallusto, F.; Carmichael, S.; Garzoni, C.; Nichols, J.;
10.1101/2020.11.04.355842 — microbiology — Posted on 2020-11-05
3513 Comparison of SARS-CoV-2 infection in two non-human primate species: rhesus and cynomolgus macaques
Boszormenyi, K. P.; Stammes, M. A.; Fagrouch, Z. C.; Kiemenyi-Kayere, G.; Niphuis, H.; Mortier, D.; van Driel, N.; Nieuwenhuis, I.; Zuiderwijk-Sick, E.; Meijer, L.; Mooij, P.; Remarque, E. J.; Koopman, G.; Hoste, A. C. R.; Sastre, P.; Haagmans, B. L.; Bontrop, R. E.; Langermans, J. A. M.; Bogers, W. M.; Verschoor, E. J.; Verstrepen, B. E.
10.1101/2020.11.05.369413 — microbiology — Posted on 2020-11-05
3514 The N-terminal domain of spike glycoprotein mediates SARS-CoV-2 infection by associating with L-SIGN and DC-SIGN
Soh, W. T.; Liu, Y.; Nakayama, E. E.; Ono, C.; Torii, S.; Nakagami, H.; Matsuura, Y.; Shioda, T.; Arase, H.
10.1101/2020.11.05.369264 — microbiology — Posted on 2020-11-05
3515 A Workflow of Integrated Resources to Catalyze Network Pharmacology Driven COVID-19 Research
Zahoranszky-Kohalmi, G.; Siramshetty, V. B.; Kumar, P.; Gurumurthy, M.; Grillo, B.; Mathew, B.; Metaxatos, D.; Backus, M.; Mierzwa, T.; Simon, R.; Grishagin, I.; Brovold, L.; Mathe, E. A.; Hall, M. D.; Michael, S. G.; Godfrey, A. G.; Mestres, J.; Jensen, L. J.; Oprea, T. I.
10.1101/2020.11.04.369041 — systems biology — Posted on 2020-11-05
3516 The Establishment of Transgenerational Epigenetic Inheritance in the C. elegans Germline is Mediated by Lipid Metabolism
Dan, P.; Chen, W.; Kai-Le, L.; Zhi-Xue, G.; Yong-Hao, L.; Hao-Wei, W.; Qiu-Yu, L.; Xi-Wei, L.; He-Yuan, S.; Yuan-Ya, J.; Qiang, F.; Qian, Z.; Lei, Z.; Huan-Huan, C.; Huan-Yin, T.; Xiao-Mei, Y.; Jian-Feng, C.; Feng, S.; Wei, L.; Fang-Lin, S.
10.1101/2020.11.04.367854 — genetics — Posted on 2020-11-05
3517 From local spectral species to global spectral communities: a benchmark for ecosystem diversity estimate by remote sensing
Rocchini, D.; Salvatori, N.; Beierkuhnlein, C.; Chiarucci, A.; de Boissieu, F.; Foerster, M.; Garzon-Lopez, C. X.; Gillespie, T. W.; Hauffe, H. C.; He, K. S.; Kleinschmit, B.; Lenoir, J.; Malavasi, M.; Moudry, V.; Nagendra, H.; Payne, D.; Simova, P.; Torresani, M.; Wegmann, M.; Feret, J.-B.
10.1101/2020.11.04.367995 — ecology — Posted on 2020-11-05
3518 Extending the integrate-and-fire model to account for metabolic dependencies
Jaras, I.; Harada, T.; Orchard, M. E.; Maldonado, P. E.; Vergara, R. C.
10.1101/2020.11.04.367102 — neuroscience — Posted on 2020-11-05
3519 Localized Chemogenetic Silencing of Inhibitory Neurons: A novel Mouse Model of Focal Cortical Seizures
Goldenberg, A. M.; Schmidt, S.; Mitelman, R.; Rubi Levy, D.; Katz, Y.; Yizhar, O.; Beck, H.; Lampl, I.
10.1101/2020.11.04.367862 — neuroscience — Posted on 2020-11-05
3522 Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell lines
Wu, L.; Xie, J.; Wang, S.; Zou, X.; Pan, T.; Zhuang, Z.; Wang, Z.; Yuan, Y.; Liu, L.; Liu, S.
10.1101/2020.11.03.367532 — cancer biology — Posted on 2020-11-05
3525 Novel imprints in mouse blastocysts are predominantly DNA methylation independent
Santini, L.; Halbritter, F.; Titz-Teixeira, F.; Suzuki, T.; Asami, M.; Ramesmayer, J.; Ma, X.; Lackner, A.; Warr, N.; Pauler, F.; Hippenmeyer, S.; Laue, E.; Farlik, M.; Bock, C.; Beyer, A.; Perry, A. C. F.; Leeb, M.
10.1101/2020.11.03.366948 — genomics — Posted on 2020-11-05
3526 Automated AI labelling of optic nerve head enables new insights into cross-ancestry glaucoma risk and genetic discovery in over 280,000 images from the UK Biobank and Canadian Longitudinal Study on Aging
Han, X.; Steven, K.; Qassim, A.; Marshall, H. N.; Bean, C.; Tremeer, M.; An, J.; Siggs, O.; Gharahkhani, P.; Craig, J. E.; Hewitt, A. W.; Trzaskowski, M.; MacGregor, S.
10.1101/2020.11.03.367623 — genetics — Posted on 2020-11-05
3529 Prevalence of sustainable and unsustainable use of wild species inferred from the IUCN Red List
Marsh, S. M. E.; Hoffmann, M.; Burgess, N. D.; Brooks, T. M.; Challender, D. W. S.; Cremona, P. J.; Hilton-Taylor, C.; Lafaye de Micheaux, F.; Lichtenstein, G.; Bohm, M.; Roe, D.
10.1101/2020.11.04.367763 — ecology — Posted on 2020-11-05
3531 Intracellular sterol sensing controls intestinal B cell differentiation
Trindade, B. C.; Ceglia, S.; Berthelette, A.; Raso, F.; Howley, K.; Muppidi, J. R.; Reboldi, A.
10.1101/2020.11.03.367177 — immunology — Posted on 2020-11-05
3533 MiniFAST: A sensitive and fast miniaturized microscope for in vivo neural recording
Juneau, J.; Duret, G.; Chu, J.; Rodriguez, A.; Morozov, S.; Aharoni, D.; Robinson, J.; St-Pierre, F.; Kemere, C.
10.1101/2020.11.03.367466 — neuroscience — Posted on 2020-11-05
3535 Vascular cognitive impairment in the mouse reshapes visual, spatial network functional connectivity.
Hall, G. R.; Boehm-Sturm, P.; Dirnagl, U.; Finke, C.; Foddis, M.; Harms, C.; Koch, S. P.; Kuchling, J.; Madan, C. R.; Mueller, S.; Sassi, C.; Sotiropoulos, S.; Trueman, R. C.; Wallis, M.; Yildirim, F. R.; Farr, T. D.
10.1101/2020.11.04.366294 — neuroscience — Posted on 2020-11-05
3537 Pumiliotoxin metabolism and molecular physiology in a poison frog
Alvarez-Buylla, A.; Payne, C. Y.; Vidoudez, C.; Trauger, S. A.; O'Connell, L. A.
10.1101/2020.11.03.367524 — physiology — Posted on 2020-11-05
3542 Genetic evidence for bidirectional causal effects between resilience and well-being.
de Vries, L. P.; Baselmans, B. M. L.; Luykx, J.; de Zeeuw, E. L.; Minica, C.; de Geus, E. J. C.; Vinkers, C. H.; Bartels, M.
10.1101/2020.11.03.366492 — genetics — Posted on 2020-11-05
3544 No leading-edge effect in North Atlantic harbor porpoises: Evolutionary and conservation implications
Ben Chehida, Y.; Loughnane, R.; Thumloup, J.; Kaschner, K.; Garilao, C.; Rosel, P. E.; Fontaine, M. C.
10.1101/2020.11.03.366542 — evolutionary biology — Posted on 2020-11-05
3547 New water and air pollution sensors added to the Sonic Kayak citizen science system for low cost environmental mapping
Griffiths, A.; Garrett, J. K.; Duffy, J. P.; Matthews, K.; Visi, F. G.; Eatock, C.; Robinson, M.; Griffiths, D. J.
10.1101/2020.11.03.366229 — ecology — Posted on 2020-11-05
3550 Environmental DNA for tracking waterhole visitation in savanna ecosystems
Farrell, M. J.; Govender, D.; Hajibabaei, M.; van der Bank, M.; Davies, T. J.
10.1101/2020.11.03.367417 — ecology — Posted on 2020-11-05
3553 Photoperiod Sensitive Energy Sorghum Responses to Environmental and Nitrogen Variabilities
Schetter, A. A.; Lin, C.-H.; Zumpf, C.; Jang, C.; Hoffmann, L.; Rooney, W. L.; Lee, D. K.
10.1101/2020.11.03.366898 — plant biology — Posted on 2020-11-05
3554 The epithelial-mesenchymal transcription factor SNAI1 represses transcription of the tumor suppressor miRNA let-7 in cancer
Wang, H.; Chirshev, E.; Hojo, N.; Suzuki, T.; Bertucci, A.; Pierce, M.; Perry, C.; Wang, R.; Zink, J. I.; Glackin, C.; Ioffe, Y.; Unternaehrer, J.
10.1101/2020.11.04.368688 — cancer biology — Posted on 2020-11-05
3555 Contrast-enhanced sonography with biomimetic lung surfactant nanodrops
Thomas, A.; Song, K.-H.; Upadhyay, A.; Papadopoulou, V.; Ramirez, D.; Beninger, R.; Lowerison, M.; Song, P.; Murray, T.; Borden, M. A.
10.1101/2020.11.03.367235 — bioengineering — Posted on 2020-11-05
3556 Olfactory rod cells: a rare cell type in the larval zebrafish olfactory epithelium with an actin-rich apical projection
Cheung, K. Y.; Jesuthasan, S. J.; Baxendale, S.; van Hateren, N. J.; Marzo, M.; Hill, C. J.; Whitfield, T. T.
10.1101/2020.11.04.367979 — developmental biology — Posted on 2020-11-05
3558 Poised cell circuits in human skin are activated in disease
Reynolds, G.; Vegh, P.; Fletcher, J.; Poyner, E.; Stephenson, E.; Goh, I.; Botting, R.; Huang, N.; Olabi, B.; Dubois, A.; Dixon, D.; Green, K.; Maunder, D.; Engelbert, J.; Efremova, M.; Polanski, K.; Jardine, L.; Jones, C.; Ness, T.; Horsfall, D.; McGrath, J.; Carey, C.; Popescu, D.-M.; Webb, S.; Wang, X.-n.; Sayer, B.; Park, J.-E.; Negri, V.; Belokhvostova, D.; Lynch, M.; McDonald, D.; Filby, A.; Hagai, T.; Meyer, K.; Husain, A.; Coxhead, J.; Vento-Tormo, R.; Behjati, S.; Lisgo, S.; Villani, A.-C.; Bacardit, J.; Jones, P.; OToole, E.; Ogg, G.; Rajan, N.; Reynolds, N.; Teichmann, S.; Watt, F.;
10.1101/2020.11.05.369363 — immunology — Posted on 2020-11-05
3562 Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics
Maniou, E.; Staddon, M.; Marshall, A.; Greene, N.; Copp, A.; Banerjee, S.; Galea, G.
10.1101/2020.11.02.364513 — developmental biology — Posted on 2020-11-05
3564 WNT responsive SUMOylation of ZIC5 exerts multiple effects on transcription to promote murine neural crest cell development
Ali, R. G.; Bellchambers, H. M.; Warr, N.; Ahmed, J. N.; Barratt, K. S.; Neill, K.; Diamand, K. E. M.; Arkell, R. M.
10.1101/2020.11.04.369124 — developmental biology — Posted on 2020-11-05
3565 Innervation modulates the functional connectivity between pancreatic endocrine cells
Yang, Y. H. C.; Briant, L. J. B.; Raab, C.; Mullapudi, S. T.; Maischein, H.-M.; Kawakami, K.; Stainier, D. Y.
10.1101/2020.11.04.368084 — cell biology — Posted on 2020-11-05
3566 A self-exciting point process to study multi-cellular spatial signaling patterns
Verma, A.; Jena, S.; Isakov, D. R.; Aoki, K.; Toettcher, J. E.; Engelhardt, B. E.
10.1101/2020.11.04.368001 — cell biology — Posted on 2020-11-05
3567 Tracing production instability in a clonally-derived CHO cell line using single cell transcriptomics
Tzani, I.; Herrmann, N.; Carillo, S.; Spargo, C. A.; Hagan, R.; Barron, N.; Bones, J.; Dilmore, W. S.; Clarke, C.
10.1101/2020.11.04.368480 — cell biology — Posted on 2020-11-05
3568 GAK and PRKCD are positive regulators of PRKN-independent mitophagy
Munson, M. J.; Mathai, B. J.; Trachsel, L.; Yoke Wui Ng, M.; Rodriguez de la Ballina, L.; Schultz, S.; Aman, Y.; Lystad, A. H.; Singh, S.; Singh, S.; Wesche, J.; Fang, E. F.; Simonsen, A.
10.1101/2020.11.05.369496 — cell biology — Posted on 2020-11-05
3569 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-05
3571 Estimating latent positions of actors using Neural Networks in R with GCN4R
Levy, J.; Bobak, C. A.; Christensen, B.; Vaickus, L. J.; O'Malley, A. J.
10.1101/2020.11.02.364935 — bioinformatics — Posted on 2020-11-05
3574 Intranasal fusion inhibitory lipopeptide prevents direct contact SARS-CoV-2 transmission in ferrets
de Vries, R. D.; Schmitz, K. S.; Bovier, F. T.; Noack, D.; Haagmans, B. L.; Biswas, S.; Rockx, B.; Gellman, S. H.; Alabi, C. A.; de Swart, R. L.; MOSCONA, A.; Porotto, M.
10.1101/2020.11.04.361154 — microbiology — Posted on 2020-11-05
3576 The translational landscape of SARS-CoV-2 and infected cells
Puray-Chavez, M.; Tenneti, K.; Vuong, H. R.; Lee, N.; Liu, Y.; Horani, A.; Huang, T.; Case, J. B.; Yang, W.; Diamond, M. S.; Brody, S. L.; Dougherty, J.; Kutluay, S. B.
10.1101/2020.11.03.367516 — microbiology — Posted on 2020-11-05
3577 SARS-CoV-2 Infects Human Engineered Heart Tissues and Models COVID-19 Myocarditis
Bailey, A. L.; Dmytrenko, O.; Greenberg, L.; Bredemeyer, A. L.; Ma, P.; Liu, J.; Penna, V.; Lai, L.; Winkler, E. S.; Sviben, S.; Brooks, E.; Nair, A. P.; Heck, K. A.; Rali, A. S.; Simpson, L.; Saririan, M.; Hobohm, D.; Stump, W. T.; Fitzpatrick, J. A.; Xie, X.; Shi, P.-Y.; Hinson, J. T.; Gi, W.-T.; Schmidt, C.; Leuschner, F.; Lin, C.-Y.; Diamond, M. S.; Greenberg, M. J.; Lavine, K. J.
10.1101/2020.11.04.364315 — immunology — Posted on 2020-11-05
3578 Immunodominant T-cell epitopes from the SARS-CoV-2 spike antigen reveal robust pre-existing T-cell immunity in unexposed individuals
Mahajan, S.; Bhojak, K.; Kode, V.; Magdalene, C. M.; Manoharan, M.; Lee, K.; Ramesh, A.; V, S. H.; Srivastava, A.; Sathian, R.; Kumar, P.; Khan, T.; Chakraborty, P.; Chaudhuri, A.
10.1101/2020.11.03.367375 — immunology — Posted on 2020-11-05
3579 SARS-CoV-2 RBD219-N1C1: A Yeast-Expressed SARS-CoV-2 Recombinant Receptor-Binding Domain Candidate Vaccine Stimulates Virus Neutralizing Antibodies and T-cell Immunity in Mice
Pollet, J.; Chen, W.-H.; Versteeg, L.; Keegan, B.; Zhan, B.; Wei, J.; Liu, Z.; Lee, J.; Kundu, R.; Adhikari, R.; Poveda, C.; Villar Mondragon, M. J.; de Araujo Leao, A. C.; Altieri Rivera, J.; Gillespie, P. M.; Strych, U.; Hotez, P. J.; Bottazzi, M. E.
10.1101/2020.11.04.367359 — immunology — Posted on 2020-11-05
3580 Evolution of Antibody Immunity to SARS-CoV-2
Gaebler, C.; Wang, Z.; Lorenzi, J. C. C.; Muecksch, F.; Finkin, S.; Tokuyama, M.; Ladinsky, M.; Cho, A.; Jankovic, M.; Schaefer-Babajew, D.; Oliveira, T. Y.; Cipolla, M.; Viant, C.; Barnes, C. O.; Hurley, A.; Turroja, M.; Gordon, K.; Millard, K. G.; Ramos, V.; Schmidt, F.; Weisblum, Y.; Jha, D.; Tankelevich, M.; Yee, J.; Shimeliovich, I.; Robbiani, D. F.; Zhao, Z.; Gazumyan, A.; Hatziioannou, T.; Bjorkman, P. J.; Mehandru, S.; Bieniasz, P. D.; Caskey, M.; Nussenzweig, M. C.
10.1101/2020.11.03.367391 — immunology — Posted on 2020-11-05
3581 DksA-dependent regulation of RpoS contributes to Borrelia burgdorferi tick-borne transmission and mammalian infectivity
Boyle, W. K.; Richards, C.; Dulebohn, D. P.; Zalud, A. K.; Shaw, J. A.; Lovas, S.; Gherardini, F. C.; Bourret, T. J.
10.1101/2020.11.04.367946 — microbiology — Posted on 2020-11-04
3584 Feedback inhibition of AMT1 NH4+-transporters mediated by CIPK15 kinase
Chen, H.-Y.; Chen, Y.-N.; Wang, H.-Y.; Liu, Z.-T.; Frommer, W. B.; Ho, C.-H.
10.1101/2020.11.03.367383 — plant biology — Posted on 2020-11-04
3585 Root and canopy traits and adaptability genes explain drought tolerance mechanism in winter wheat.
Nehe, A.; Foulkes, J.; Ozturk, I.; Awais, R.; York, L.; Kefauver, S.; Ozdemir, F.; Morgunov, A.
10.1101/2020.11.04.367904 — plant biology — Posted on 2020-11-04
3588 Human-specific expansion of 22q11.2 low copy repeats
Vervoort, L.; Vermeesch, J. R.; Dierckxsens, N.; Pereboom, Z.; Rocchi, M.; Capozzi, O.; Shaikh, T. H.
10.1101/2020.11.04.367920 — genetics — Posted on 2020-11-04
3595 Modulating glial genes involved in synaptic function mitigates pathogenesis and behavioral deficits in a Drosophila model of Huntington's Disease
Onur, T. S.; Laitman, A.; Zhao, H.; Keyho, R.; Kim, H.; Wang, J.; Mair, M.; Perez, A.; de Haro, M.; Wang, H.; Wan, Y.-W.; Allen, G.; Lu, B.; Al-Ramahi, I.; Liu, Z.; Botas, J.
10.1101/2020.11.03.367326 — systems biology — Posted on 2020-11-04
3598 9p21 Loss Defines the Evolutionary Patterns of Aggressive Renal Cell Carcinomas
Carbone, F.; Huang, J. K.; Perelli, L.; Del Poggetto, E.; Gutschner, T.; Tomihara, H.; Soeung, M.; Lam, T. N. A.; Xia, R.; Zhu, C.; Song, X.; Zhang, J.; Sircar, K.; Malouf, G. G.; Sgambato, A.; Karam, J. A.; Gao, J.; Jonasch, E.; Viale, A.; Draetta, G. F.; Futreal, A.; Bakouny, Z.; Van Allen, E. M.; Choueiri, T.; Msaouel, P.; Litchfield, K.; Turajlic, S.; Heffernan, T. P.; Chen, Y. B.; DiNatale, R. G.; Hakimi, A. A.; Bristow, C. A.; Tannir, N. M.; Carugo, A.; Genovese, G.
10.1101/2020.11.03.367433 — cancer biology — Posted on 2020-11-04
3599 Spatial structure impacts adaptive therapy by shaping intra-tumoral competition
Strobl, M. A. R.; Gallaher, J.; West, J.; Robertson-Tessi, M.; Maini, P. K.; Anderson, A.
10.1101/2020.11.03.365163 — cancer biology — Posted on 2020-11-04
3600 A Versatile Oblique Plane Microscope for Large-Scale and High-Resolution Imaging of Subcellular Dynamics.
Sapoznik, E.; Chang, B.-J.; Huh, J.; Ju, R. J.; Azarova, E.; Pohlkamp, T.; Welf, E. S.; Broadbent, D.; Carisey, A. F.; Stehbens, S. J.; Lee, K.-m.; Marin, A.; Hanker, A. B.; Schmidt, J. C.; Arteaga, C. L.; Yang, B.; Kobayashi, Y.; Tata, P. R.; Kruithoff, R.; Doubrovinski, K.; Shepherd, D. P.; Millett-Sikking, A.; York, A. G.; Dean, K. M.; Fiolka, R. P.
10.1101/2020.04.07.030569 — biophysics — Posted on 2020-11-04
3605 Lymphocyte-Specific Biomarkers Associated with Preterm Birth and Bronchopulmonary Dysplasia
Bhattacharya, S.; Mereness, J.; Baran, A.; Misra, R.; Peterson, D.; Ryan, R.; Reynolds, A. M.; Pryhuber, G.; Mariani, T. J.
10.1101/2020.11.03.367201 — genomics — Posted on 2020-11-04
3606 Analysis Of Polycerate Mutants Reveals The Evolutionary Co-Option Of HOXD1 To Determine The Number And Topology Of Horns In Bovidae
Allais-Bonnet, A.; Hintermann, A.; Deloche, M.-C.; Cornette, R.; Bardou, P.; Naval-Sanchez, M.; Pinton, A.; Haruda, A.; Grohs, C.; Zakany, J.; Bigi, D.; Medugorac, I.; Putelat, O.; Greyvenstein, O.; Hadfield, T.; Ben Jemaa, S.; Bunevski, G.; Menzi, F.; Hirter, N.; Paris, J. M.; Hedges, J.; Palhiere, I.; Rupp, R.; Lenstra, J. A.; Gidney, L.; Lesur, J.; Schafberg, R.; Stache, M.; Wandhammer, M.-D.; Arbogast, R.-M.; Guintard, C.; Blin, A.; Boukadiri, A.; Riviere, J.; Esquerre, D.; Donnadieu, C.; Danchin-Burge, C.; Reich, C. M.; Riley, D.; van Marle-Koster, E.; Cockett, N.; Hayes, B. J. A.; Droege
10.1101/2020.11.04.363069 — genomics — Posted on 2020-11-04
3607 Improved chromosome level genome assembly of the Glanville fritillary butterfly (Melitaea cinxia) based on SMRT Sequencing and linkage map.
Blande, D.; Smolander, O.-P.; Ahola, V.; Rastas, P.; Tanskanen, J.; Kammonen, J. I.; Oostra, V.; Pellegrini, L.; Ikonen, S.; Dallas, T.; DiLeo, M. F.; Duplouy, A.; Duru, I. C.; Halimaa, P.; Kahilainen, A.; Kuwar, S. S.; Karenlampi, S. O.; Lafuente, E.; Luo, S.; Makkonen, J.; Nair, A.; Celorio-Mancera, M. d. l. P.; Pennanen, V.; Ruokolainen, A.; Sundell, T.; Tervahauta, A. I.; Twort, V.; van Bergen, E.; Osterman-Udd, J.; Paulin, L.; Frilander, M. J.; Auvinen, P.; Saastamoinen, M.
10.1101/2020.11.03.364950 — genomics — Posted on 2020-11-04
3611 Developmental regulation of mitotic chromosome formation revealed by condensin reporter mice
Taylor, G. C. A.; Macdonald, L. A.; Bui, M.; Scott, L.; Christodoulou, I.; Wills, J. C.; Papadopoulos, D.; Wood, A. J.
10.1101/2020.11.04.367847 — cell biology — Posted on 2020-11-04
3615 Comparative molecular and immunoregulatory analysis of extracellular vesicles from Candida albicans and Candida auris.
Zamith-Miranda, D.; Heyman, H. M.; Couvillion, S. P.; Cordero, R. J. B.; Rodrigues, M.; Nimrichter, L.; Casadevall, A.; Amatuzzi, R.; Alves, L. R.; Nakayasu, E. S.; Nosanchuk, J. D.
10.1101/2020.11.04.368472 — microbiology — Posted on 2020-11-04
3616 Genomic and morphologic characterization of a planktonic Thiovulum (Campylobacterota) dominating the surface waters of the sulfidic Movile Cave, Romania
Bizic, M.; Brad, T.; Barbu-Tudoran, L.; Aerts, J.; Ionescu, D.; Popa, R.; Ody, J.; Flot, J.-F.; Tighe, S.; Vellone, D.; Sarbu, S. M.
10.1101/2020.11.04.367730 — microbiology — Posted on 2020-11-04
3620 Wing shape evolution in bombycoid moths reveals two distinct strategies for maneuverable flight
Aiello, B. R.; Sikandar, U. B.; Minoguchi, H.; Kimball, K.; Hamilton, C. A.; Kawahara, A. Y.; Sponberg, S.
10.1101/2020.10.27.358176 — physiology — Posted on 2020-11-04
3621 CLEP: A Hybrid Data- and Knowledge- Driven Framework for Generating Patient Representations
Bharadhwaj, V. S.; Ali, M.; Birkenbihl, C.; Mubeen, S.; Lehmann, J.; Hofmann-Apitius, M.; Hoyt, C. T.; Domingo-Fernandez, D.
10.1101/2020.08.20.259226 — bioinformatics — Posted on 2020-11-04
3626 Copy number-aware deconvolution of tumor-normal DNA methylation profiles
Larose Cadieux, E.; Tanic, M.; Wilson, G. A.; Baker, T.; Dietzen, M.; Dhami, P.; Vaikkinen, H.; Watkins, T. B. K.; Kanu, N.; Veeriah, S.; Jamal-Hanjani, M.; McGranahan, N.; Feber, A.; Swanton, C.; TRACERx Consortium, ; Beck, S.; Demeulemeester, J.; Van Loo, P.
10.1101/2020.11.03.366252 — genomics — Posted on 2020-11-04
3627 Epigenomic reprogramming of repetitive noncoding RNAs and IFN-stimulated genes by mutant KRAS
Reggiardo, R. E.; Velandi Maroli, S.; Halasz, H.; Ozen, M.; Carrillo, D.; LaMontagne, E.; Whitehead, L.; Kim, E.; Malik, S.; Fernandes, J.; Marinov, G.; Collisson, E.; Demirci, U.; Kim, D. H.
10.1101/2020.11.04.367771 — genomics — Posted on 2020-11-04
3628 PROXIMATE AND GENETIC ANALYSIS OF BLACKFIN TUNA (T. atlanticus)
Nunez Mata, Y. M.; Rios Rodriguez, J. R.; Perales Torres, A. L.; De la Rosa Reyna, X. F.; Vazquez Rodriguez, J. A.; Fernandez Santos, N. A.; Martinez Montoya, H.
10.1101/2020.11.03.366153 — genetics — Posted on 2020-11-04
3630 Long-range gene regulation network of the MGMT enhancer in modulating glioma cell sensitivity to temozolomide
He, A.; Chen, B.; Bi, J.; Wang, W.; Chen, J.; Qian, Y.; Shi, T.; Zhao, Z.; Shi, J.; Yang, H.; Zhang, L.; Lu, W.
10.1101/2020.11.03.367268 — genetics — Posted on 2020-11-04
3631 Molecular Evolution of Podocyte Slit-diaphragm Proteins
Mulukala, S. N.; Kambhampati, V.; Qadri, A. S.; Pasupulati, A. k.
10.1101/2020.11.03.366161 — evolutionary biology — Posted on 2020-11-04
3633 Environmental factors drive release of Perkinsus marinus from infected oysters
Gignoux-Wolfsohn, S. A.; Newcomb, M. S. R.; Ruiz, G. M.; Pagenkopp Lohan, K. M.
10.1101/2020.11.03.366781 — ecology — Posted on 2020-11-04
3634 Integrated Use of Compost and Nitrogen Fertilizer and their Effects on Yield and Yield Components of Wheat: A Pot Experiment
Gari, B. D.; Berecha, G.; Mamuye, M.; Diriba, O. H.; Nebiyu, A.; Nigussie, A.; Hanc, A.; Svehla, P.
10.1101/2020.10.07.329524 — ecology — Posted on 2020-11-04
3636 Human Chr18: "Stakhanovite" Genes, Missing and uPE1 Proteins in Liver Tissue and HepG2 Cells
Krasnov, G. S.; Lisitsa, A. V.; Ponomarenko, E. A.; Radko, S. P.; Ptitsyn, K. G.; Shapovalova, V. V.; Timoshenko, O. S.; Khmeleva, S. A.; Kurbatov, L. K.; Kiseleva, Y. Y.; Ilgisonis, E. V.; Pyatnitskiy, M. A.; Poverennaya, E. V.; Kiseleva, O. I.; Vakhrushev, I. V.; Tsvetkova, A. V.; Buromski, I. V.; Markin, S. S.; Zgoda, V. G.; Archakov, A. I.
10.1101/2020.11.04.358739 — molecular biology — Posted on 2020-11-04
3637 Aurora-A phosphorylates splicing factors and regulates alternative splicing
Damodaran, A. P.; Gavard, O.; Gagne, J.-P.; Rogalska, M. E.; Mancini, E.; Courtheoux, T.; Cailloce, J.; Mereau, A.; Poirier, G. G.; Valcarcel, J.; Watrin, E.; Prigent, C.
10.1101/2020.11.04.368498 — molecular biology — Posted on 2020-11-04
3638 The bacterial toxin ExoU requires a host trafficking chaperone for transportation and to induce necrosis
Deruelle, V.; Bouillot, S.; Job, V.; Taillebourg, E.; Fauvarque, M.-O.; Attree, I.; Huber, P.
10.1101/2020.11.04.367706 — microbiology — Posted on 2020-11-04
3640 Muscle Atrophy: Different Strains of Mice Respond Differently to Single Limb Immobilization
Maroni, C.; Friedman, M.; Zhang, Y.; McClure, M.; Fulle, S.; Farber, C.; Donahue, H.
10.1101/2020.11.03.367169 — physiology — Posted on 2020-11-04
3646 Derivation of predator functional responses using a mechanistic approach in a natural system
Beardsell, A.; Gravel, D.; Berteaux, D.; Gauthier, G.; Clermont, J.; Careau, V.; Lecomte, N.; Juhasz, C.-C.; Royer-Boutin, P.; Bety, J.
10.1101/2020.11.04.368670 — ecology — Posted on 2020-11-04
3647 Using Community Science to Reveal the Global Chemogeography of River Metabolomes
Garayburu-Caruso, V. A.; Danczak, R. E.; Stegen, J.; Renteria, L.; MacCall, M.; Goldman, A. E.; Chu, R. K.; Toyoda, J.; Resch, C. T.; Torgeson, J. M.; Wells, J.; Fansler, S.; Kumar, S.; Graham, E. B.
10.1101/2020.11.02.362905 — ecology — Posted on 2020-11-04
3648 Genetically encoded ratiometric biosensor for probing lysosomal pH in mammalian cells and C. elegans
Chin, M. Y.; Patwardhan, A. R.; Ang, K.-H.; Wang, A. L.; Alquezar, C.; Welch, M.; Grabe, M.; Arkin, M. R.; Kao, A. W.
10.1101/2020.11.04.368654 — cell biology — Posted on 2020-11-04
3649 Diversity of ACE2 and its interaction with SARS-CoV-2 receptor binding domain
Gan, J. L.; Huang, R.; Warner, G.; Kelley, A.; McGregor, D.; Smider, V. V.
10.1101/2020.10.25.354548 — molecular biology — Posted on 2020-11-04
3651 Strong coupling and local control of dimensionality across brain areas
Dahmen, D.; Recanatesi, S.; Ocker, G. K.; Jia, X.; Helias, M.; Shea-Brown, E.
10.1101/2020.11.02.365072 — neuroscience — Posted on 2020-11-04
3652 Pruriception and neuronal coding in nociceptor subtypes in human and nonhuman primates
Klein, A.; Solinski, H. J.; Malewicz, N.; Ieong, H. F.-h.; Shimada, S.; Hartke, T. V.; Wooten, M.; Wu, G.; Hoon, M. A.; LaMotte, R. H.; Ringkamp, M.
10.1101/2020.11.04.368597 — neuroscience — Posted on 2020-11-04
3654 Brain volumetric changes in the general population following the COVID-19 outbreak and lockdown
Salomon, T.; Cohen, A.; Barazany, D.; Ben-Zvi, G.; Botvinik-Nezer, R.; Gera, R.; Oren, S.; Roll, D.; Rozic, G.; Saliy, A.; Tik, N.; Tsarfati, G.; Tavor, I.; Schonberg, T.; Assaf, Y.
10.1101/2020.09.08.285007 — neuroscience — Posted on 2020-11-04
3655 Unsupervised machine learning reveals key immune cell subsets in COVID-19, rhinovirus infection, and cancer therapy
Barone, S. M.; Paul, A. G. A.; Muehling, L. M.; Lannigan, J. A.; Kwok, W. W.; Turner, R. B.; Woodfolk, J. A.; Irish, J. M.
10.1101/2020.07.31.190454 — systems biology — Posted on 2020-11-04
3657 Transcriptome atlas of Phalaenopsis equestris
Klepikova, A. V.; Kasianov, A. S.; Ezhova, M. A.; Penin, A. A.; Logacheva, M. D.
10.1101/2020.11.03.366260 — plant biology — Posted on 2020-11-04
3658 Data driven mathematical model of colon cancer progression
Kirshtein, A.; Akbarinejad, S.; Hao, W.; Le, T.; Aronow, R. A.; Shahriyari, L.
10.1101/2020.11.02.365668 — cancer biology — Posted on 2020-11-04
3659 E-cadherin promotes cell hyper-proliferation in breast cancer
Russo, G. C.; Karl, M. N.; Clark, D.; Cui, J.; Carney, R.; Su, B.; Starich, B. A.; Lih, T.-S.; Zhang, Q.; Wu, P.-h.; Lee, M.-H.; Leong, H. S.; Zhang, H.; Wirtz, D.
10.1101/2020.11.04.368746 — cancer biology — Posted on 2020-11-04
3660 Strengthening the BioCompute Standard by Crowdsourcing on PrecisionFDA
Stephens, S. H.; King, C. H.; Watford, S.; Patel, J.; Dean, D. A.; Koc, S.; Xiao, N.; Donaldson, E.; Thompson, E.; Purkayastha, A.; Mazumder, R.; Johanson, E.; Keeney, J.
10.1101/2020.11.02.365528 — bioinformatics — Posted on 2020-11-04
3662 LyGo: A platform for rapid screening of lytic polysaccharide monooxygenase production
Hernandez-Rollan, C.; Falkenberg, K. B.; Rennig, M.; Bertelsen, A. B.; Ipsen, J. O.; Brander, S.; Daley, D. O.; Johansen, K. S.; Norholm, M. H. H.
10.1101/2020.11.04.368555 — bioengineering — Posted on 2020-11-04
3665 Polygenic Scores Predict the Development of Alcohol and Nicotine Use Problems from Adolescence through Young Adulthood
Deak, J. D.; Clark, D. A.; Liu, M.; Durbin, C. E.; Iacono, W. G.; McGue, M.; Vrieze, S. I.; Hicks, B. M.
10.1101/2020.07.29.227439 — genetics — Posted on 2020-11-04
3666 Essential histone chaperones collaborate to regulate transcription and chromatin integrity
Viktorovskaya, O.; Chuang, J.; Jain, D.; Reim, N. I.; Lopez-Rivera, F.; Murawska, M.; Spatt, D.; Churchman, L. S.; Park, P. J.; Winston, F.
10.1101/2020.11.04.368589 — genetics — Posted on 2020-11-04
3669 Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus
Gopal, V.; Nilsson-Payant, B. E.; French, H.; Siegers, J. Y.; tenOever, B.; Yung, W.-s.; Hardwick, M.; te Velthuis, A. J. W.
10.1101/2020.11.02.365833 — microbiology — Posted on 2020-11-04
3670 Synergistic Coding of Human Odorants in the Mosquito Brain
Shankar, S.; Tauxe, G. M.; Spikol, E. D.; Li, M.; Akbari, O. S.; Giraldo, D.; McMeniman, C. J.
10.1101/2020.11.02.365916 — neuroscience — Posted on 2020-11-04
3671 Plasticity in visual cortex is disrupted in a mouse model of tauopathy and neurodegeneration
Papanikolaou, A.; Rodrigues, F. R.; Holeniewska, J.; Phillips, K. G.; Saleem, A. B.; Solomon, S. G.
10.1101/2020.11.02.365767 — neuroscience — Posted on 2020-11-04
3678 Transdiagnostic dimensions of psychopathology explain individuals' unique deviations from normative neurodevelopment in brain structure
Parkes, L.; Moore, T. M.; Calkins, M. E.; Cook, P. A.; Cieslak, M.; Roalf, D. R.; Wolf, D. H.; Gur, R. C.; Gur, R. E.; Satterthwaite, T. D.; Bassett, D. S.
10.1101/2020.06.11.147009 — neuroscience — Posted on 2020-11-04
3679 Neural circuit basis of aversive odour processing in Drosophila from sensory input to descending output.
Huoviala, P.; Dolan, M.-J.; Love, F.; Myers, P.; Frechter, S.; Namiki, S.; Pettersson, L.; Roberts, R. J. V.; Turnbull, R.; Mitrevica, Z.; Breads, P.; Schlegel, P.; Bates, A. S. S.; Rodrigues, T.; Aso, Y.; Bock, D.; Rubin, G. M.; Stensmyr, M.; Card, G.; Costa, M.; Jefferis, G. S. X. E.
10.1101/394403 — neuroscience — Posted on 2020-11-04
3681 Osteocyte Transcriptome Mapping Identifies a Molecular Landscape Controlling Skeletal Homeostasis and Susceptibility to Skeletal Disease
Youlten, S. E.; Kemp, J. P.; Logan, J. G.; Ghirardello, E. J.; Sergio, C. M.; Dack, M. R. G.; Guilfoyle, S. E.; Leitch, V. D.; Butterfield, N. C.; Komla-Ebri, D.; Chai, R. C.; Corr, A. P.; Smith, J. T.; Mohanty, S. T.; Morris, J. A.; McDonald, M. M.; Quinn, J. M. W.; McGlade, A. R.; Bartonicek, N.; Jansson, M.; Hatzikotoulas, K.; Irving, M. D.; Beleza-Meireles, A.; Rivadeneira, F.; Duncan, E. L.; Richards, J. B.; Adams, D. J.; Lelliott, C. J.; Brink, R.; Phan, T. G.; Eisman, J. A.; Evans, D. M.; Zeggini, E.; Baldock, P. A.; Bassett, J. H. D.; Williams, G. R.; Croucher, P. I.
10.1101/2020.04.20.051409 — systems biology — Posted on 2020-11-04
3682 RuBisCO adaptation is more limited by phylogenetic constraint than by catalytic trade-off in plants
Bouvier, J. W.; Emms, D. M.; Rhodes, T.; Nielsen, J. R.; Bolton, J. S.; Eddershaw, A.; Brasnett, A.; Unitt, A.; Whitney, S. M.; Kelly, S.
10.1101/2020.09.15.298075 — plant biology — Posted on 2020-11-04
3685 Connection Stripes in the Primate Insula
Krockenberger, M.; Saleh, T. O.; Logothetis, N. K.; Evrard, H. C.
10.1101/2020.11.03.361055 — neuroscience — Posted on 2020-11-04
3688 Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
Filbin, M. R.; Mehta, A.; Schneider, A. M.; Kays, K. R.; Guess, J. R.; Gentili, M.; Fenyves, B. G.; Charland, N. C.; Gonye, A. L. K.; Gushterova, I.; Khanna, H. K.; LaSalle, T. J.; Lavin-Parsons, K. M.; Lilley, B. M.; Lodenstein, C. L.; Manakongtreecheep, K.; Margolin, J. D.; McKaig, B. N.; Rojas-Lopez, M.; Russo, B. C.; Sharma, N.; Tantivit, J.; Thomas, M. F.; Gerszten, R. E.; Heimberg, G. S.; Hoover, P. J.; Lieb, D. J.; Lin, B.; Ngo, D.; Pelka, K.; Reyes, M.; Smillie, C. S.; Waghray, A.; Wood, T. E.; Zajac, A. S.; Jennings, L. J.; Grundberg, I.; Bhattacharyya, R. P.; Parry, B. A.; Villani, A
10.1101/2020.11.02.365536 — systems biology — Posted on 2020-11-04
3691 Multi-compartment tumor organoids
Lee, M.-H.; Rahmanto, Y. S.; Russo, G. C.; Wu, P.-h.; Gilkes, D.; Kiemen, A.; Miyamoto, T.; Yu, Y.; Habibi, M.; Shih, I.-M.; Wang, T.-L.; Wirtz, D.
10.1101/2020.11.03.367334 — cancer biology — Posted on 2020-11-04
3692 Protein Structural Alignments From Sequence
Morton, J.; Strauss, C.; Blackwell, R.; Berenberg, D.; Gligorijevic, V.; Bonneau, R.
10.1101/2020.11.03.365932 — bioinformatics — Posted on 2020-11-04
3694 Targeted long-read sequencing resolves complex structural variants and identifies missing disease-causing variants
Miller, D. E.; Sulovari, A.; Wang, T.; Loucks, H.; Hoekzema, K.; Munson, K. M.; Lewis, A. P.; Almanza Fuerte, E. P.; Paschal, C. R.; Thies, J.; Bennett, J. T.; Glass, I.; Dipple, K. M.; Patterson, K.; Bonkowski, E. S.; Nelson, Z.; Squire, A.; Sikes, M.; Beckman, E.; Bennett, R. L.; Earl, D.; Lee, W.; Allikmets, R.; Perlman, S. J.; Chow, P.; Hing, A. V.; Adam, M. P.; Sun, A.; Lam, C.; Chang, I.; University of Washington Center for Mendelian Genomics, ; Cherry, T.; Chong, J. X.; Bamshad, M. J.; Nickerson, D. A.; Mefford, H. C.; Doherty, D.; Eichler, E. E.
10.1101/2020.11.03.365395 — genomics — Posted on 2020-11-04
3697 Analysing the Yeast Complexome - The Complex Portal rising to the challenge
Meldal, B. H. M.; Pons, C.; Perfetto, L.; del-Toro, N.; Wong, E.; Aloy, P.; Hermjakob, H.; Orchard, S.; Porras, P.
10.1101/2020.11.03.367086 — systems biology — Posted on 2020-11-04
3701 Disinhibition mediated by reciprocal hypothalamic and raphe GABAergic projections promotes wakefulness
Gazea, M.; Furdan, S.; Sere, P.; Oesch, L.; Molnár, B.; Di Giovanni, G. D.; Adamantidis, A. R.; Lorincz, M. L.
10.1101/2020.11.04.367722 — neuroscience — Posted on 2020-11-04
3703 Titan mice are a unique bred mammalian model to study obesity and aspects of metabolic syndrome
de-Diego, I.; Sanz-Moreno, A.; Müller-Eigner, A.; Venkateswaran Venkatasubramani, A.; Langhammer, M.; Gerlini, R.; Rathkolb, B.; Aguilar-Pimentel, A.; Klein-Rodewald, T.; Calzada-Wack, J.; Becker, L.; Imhof, A.; Meng, C.; Ludwig, C.; Koch, F.; Caton, V.; Brenmoehl, J.; Fuchs, H.; Gailus-Durner, V.; Hoeflich, A.; Hrabe de Angelis, M.; Peleg, S.
10.1101/2020.05.11.088625 — biochemistry — Posted on 2020-11-04
3704 A genomic amplification affecting a carboxylesterase gene cluster confers organophosphate resistance in the mosquito Aedes aegypti: from genomic characterization to high-throughput field detection
Cattel, J.; Haberkorn, C.; Laporte, F.; Gaude, T.; Cumer, T.; Renaud, J.; Sutherland, I. W.; Hertz, J. C.; Bonneville, J.-M.; Arnaud, V.; Nous, C.; Fustec, B.; Boyer, S.; Marcombe, S.; David, J.-P.
10.1101/2020.06.08.139741 — evolutionary biology — Posted on 2020-11-04
3705 Human Dicer helicase domain recruits PKR and dsRNA binding proteins during viral infection
Montavon, T. C.; Baldaccini, M.; Lefevre, M.; Girardi, E.; Chane-Woon-Ming, B.; Messmer, M.; Hammann, P.; Chicher, J.; Pfeffer, S.
10.1101/2020.05.14.095356 — microbiology — Posted on 2020-11-04
3706 The composition of the microbiota in the full-term fetal gut and amniotic fluid: a bovine caesarean section study
Husso, A.; Lietaer, L.; Pessa-Morikawa, T.; Grönthal, T.; Govaere, J.; Van Soom, A.; Iivanainen, A.; Opsomer, G.; Niku, M.
10.1101/2020.09.28.309476 — microbiology — Posted on 2020-11-04
3711 Nitrogen Availability Modulates the Host Control of the Barley Rhizosphere Microbiota.
Alegria Terrazas, R.; Robertson-Albertyn, S.; Corral, A. M.; Escudero-Martinez, C.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P. E.; Paterson, E.; Baggs, L. M.; Abbott, J.; Bulgarelli, D.
10.1101/605204 — plant biology — Posted on 2020-11-04
3712 Prediction of vascular ageing based on smartphone acquired PPG signals
Dall'Olio, L.; Curti, N.; Remondini, D.; Harb, Y. S.; Asselbergs, F. W.; Castellani, G.; Uh, H.-W.
10.1101/2020.05.26.116186 — biophysics — Posted on 2020-11-04
3715 Glypicans specifically regulate Hedgehog signaling through their interaction with Ihog in cytonemes
Simon, E.; Jimenez-Jimenez, C.; Seijo-Barandiaran, I.; Aguilar, G.; Sanchez-Hernandez, D.; Aguirre-Tamaral, A.; Gonzalez-Mendez, L.; Ripoll, P.; Guerrero, I.
10.1101/2020.11.04.367797 — developmental biology — Posted on 2020-11-04
3716 ASPP2/PP1 complexes maintain the integrity of pseudostratified epithelia undergoing remodelling during morphogenesis
Royer, C.; Sandham, E.; Slee, E.; Godwin, J.; Veits, N.; Hathrell, H.; Zhou, F.; Leonavicius, K.; Garratt, J.; Narendra, T.; Vincent, A.; Jones, C.; Child, T.; Coward, K.; Graham, C.; Lu, X.; Srinivas, S.
10.1101/2020.11.03.366906 — developmental biology — Posted on 2020-11-04
3717 The spatial self-organization within pluripotent stem cell colonies is continued in detaching aggregates
Elsafi Mabrouk, M. H.; Goetzke, R.; Abagnale, G.; Yesilyurt, B.; Salz, L.; Zeevaert, K.; Ma, Z.; Toledo, M. A. S.; Li, R.; Costa, I. G.; Pachauri, V.; Schnakenberg, U.; Zenke, M.; Wagner, W.
10.1101/2020.11.03.366518 — cell biology — Posted on 2020-11-04
3718 The mitochondrial permeability transition pore activates a maladaptive mitochondrial unfolded protein response
Angeli, S.; Foulger, A.; Peiris, T. H.; Gerencser, A.; Chamoli, M.; Bhaumik, D.; Shahmirzadi, A. A.; Andersen, J.; Lithgow, G.
10.1101/2020.11.03.366815 — cell biology — Posted on 2020-11-04
3719 Role and Dynamics of Vacuolar pH during Cell-in-Cell mediated Death
Su, Y.; Ren, H.; Tang, M.; Zheng, Y.; Zhang, B.; Wang, C.; Hou, X.; Niu, Z.; Gao, L.; Chen, Z.; Luo, T.; Sun, Q.
10.1101/2020.11.03.364877 — cell biology — Posted on 2020-11-04
3720 Role of an atypical cadherin gene, Cdh23 in prepulse inhibition and its implication in schizophrenia
Balan, S.; Ohnishi, T.; Watanabe, A.; Ohba, H.; Iwayama, Y.; Toyoshima, M.; Hara, T.; Hisano, Y.; Miyasaka, Y.; Toyota, T.; Shimamoto-Mitsuyama, C.; Maekawa, M.; Numata, S.; Ohmori, T.; Shimogori, T.; Kikkawa, Y.; Hayashi, T.; Yoshikawa, T.
10.1101/2020.10.29.360180 — genetics — Posted on 2020-11-04
3722 Differential functional neural circuitry behind autism subtypes with marked imbalance between social-communicative and restricted repetitive behavior symptom domains
Bertelsen, N.; Landi, I.; Bethlehem, R. A. I.; Seidlitz, J.; Busuoli, E. M.; Mandelli, V.; Satta, E.; Trakoshis, S.; Auyeung, B.; Kundu, P.; Loth, E.; Dumas, G.; Baumeister, S.; Beckmann, C. F.; Bolte, S.; Bourgeron, T.; Charman, T.; Durston, S.; Ecker, C.; Holt, R.; Johnson, M. H.; Jones, E. J. H.; Mason, L.; Meyer-Lindenberg, A.; Moessnang, C.; Oldehinkel, M.; Persico, A.; Tillmann, J.; Williams, S. C. R.; Spooren, W.; Murphy, D. G. M.; Buitelaar, J. K.; EU-AIMS LEAP group, ; Baron-Cohen, S.; Lai, M.-C.; Lombardo, M. V.
10.1101/2020.05.08.083758 — neuroscience — Posted on 2020-11-04
3723 Transcriptional Network Orchestrating Regional Patterning of Cortical Progenitors
Ypsilanti, A. R.; Pattabiraman, K.; Catta-Preta, R.; Golonzhka, O.; Lindtner, S.; Tang, K.; Jones, I.; Abnousi, A.; Juric, I.; Hu, M.; Shen, Y.; Dickel, D. E.; Visel, A.; Pennachio, L. A.; Hawrylycz, M.; Thompson, C.; Zeng, H.; Barozzi, I.; Nord, A. S.; Rubenstein, J. L. R.
10.1101/2020.11.03.366914 — neuroscience — Posted on 2020-11-04
3724 Heritability of cortical morphology reflects a sensory-fugal plasticity gradient
Vainik, U.; Paquola, C.; Wang, X.; Zheng, Y.-Q.; Bernhardt, B.; Misic, B.; Dagher, A.
10.1101/2020.11.03.366419 — neuroscience — Posted on 2020-11-04
3728 Linkage Disequilibrium and Heterozygosity Modulate the Genetic Architecture of Human Complex Phenotypes
Holland, D.; Frei, O.; Desikan, R.; Fan, C. C.; Shadrin, A.; Smeland, O.; Andreassen, O. A.; Dale, A.
10.1101/705285 — genomics — Posted on 2020-11-03
3729 Morphological stasis masks ecologically divergent coral species on tropical reefs
Bongaerts, P.; Cooke, I. R.; Ying, H.; Wels, D.; den Haan, S.; Hernandez-Agreda, A.; Brunner, C. A.; Dove, S.; Englebert, N.; Eyal, G.; Foret, S.; Grinblat, M.; Hay, K. B.; Harii, S.; Hayward, D. C.; Lin, Y.; Mihaljevic, M.; Moya, A.; Muir, P.; Sinniger, F.; Smallhorn-West, P.; Torda, G.; Ragan, M. A.; van Oppen, M. J.; Hoegh-Guldberg, O.
10.1101/2020.09.04.260208 — evolutionary biology — Posted on 2020-11-03
3730 One Health, One Hive: A scoping review of honey bees, climate change, pollutants, and antimicrobial resistance
de Jongh, E. J.; Harper, S. L.; Yamamoto, S. S.; Wright, C. J.; Wilkinson, C. W.; Ghosh, S.; Otto, S. J. G.
10.1101/2020.11.03.366377 — ecology — Posted on 2020-11-03
3738 Pancreatic cancer stem cells (CSCs) are regulated via a feedback-loop of telomerase activity and stemness factors
Walter, K.; Rodriguez-Aznar, E.; Ventura-Ferreira, M. S.; Frappant, P. O.; Dittrich, T.; Tiwary, K.; Meessen, S.; Lerma, L.; Schulte, L. A.; Arnold, F.; Azoitei, N.; Erkan, M.; Lehel, A.; Bruemmendorf, T.; Seufferlein, T.; Kleger, A.; Tabares, E.; Guenes, C.; Beier, F.; Sainz, B.; Hermann, P. C.
10.1101/2020.11.02.361931 — cancer biology — Posted on 2020-11-03
3741 Overcoming Resistance to BRAFV600E Inhibition in Melanoma by Deciphering and Targeting Personalized Protein Network Alterations
Vasudevan, S.; Flashner-Abramson, E.; Adejumobi, I.; Vilencki, D.; Stefansky, S.; Rubinstein, A. M.; Kravchenko-Balasha, N.
10.1101/2020.11.03.366245 — systems biology — Posted on 2020-11-03
3742 Seeking an optimal dosing regimen for OZ439-DSM265 combination therapy for treating uncomplicated falciparum malaria
Dini, S.; Zaloumis, S. G.; Price, D. J.; Gobeau, N.; Kuemmel, A.; Cherkaoui, M.; Moehrle, J. J.; McCarthy, J. S.; Simpson, J. A.
10.1101/2020.11.02.366112 — pharmacology and toxicology — Posted on 2020-11-03
3743 Intraspecific variation in symbiont density in an insect-microbe symbiosis
Parker, B. J.; Hrcek, J.; McLean, A. H. C.; Brisson, J. A.; Godfray, H. C. J.
10.1101/2020.11.03.365353 — evolutionary biology — Posted on 2020-11-03
3744 Identification of novel disease relevant genetic modifiers affecting the SHH pathway in the developing brain
Mecklenburg, N.; Kowalczyk, I.; Witte, F.; Goerne, J.; Laier, A.; Gonschior, H.; Lehmann, M.; Richter, M.; Sporbert, A.; Purfuerst, B.; Hubner, N.; Hammes, A.
10.1101/2020.11.03.366302 — developmental biology — Posted on 2020-11-03
3748 The Hsc70 Disaggregation Machinery RemovesMonomer Units Directly from α-Synuclein FibrilEnds
Schneider, M. M.; Gautam, S.; Herling, T. W.; Andrzejwska, E.; Krainer, G.; Miller, A. M.; Peter, Q. A. E.; Ruggeri, F. S.; Vendruscolo, M.; Bracher, A.; Dobson, C. M.; Hartl, F.-U.; Knowles, T.
10.1101/2020.11.02.365825 — biophysics — Posted on 2020-11-03
3749 Senotherapeutic peptide reduces skin biological age and improves skin health markers
Zonari, A.; Brace, L. E.; Al-Katib, K. Z.; Porto, W. F.; Foyt, D.; Guiang, M.; Cruz, E. A. O.; Marshall, B.; Salgueiro, W. G.; Inan, M. D.; Rahman, M.; Anupom, T.; Vanapalli, S.; Mori, M. A.; Franco, O. L.; Oliveira, C. R.; Boroni, M.; Carvalho, J. L.
10.1101/2020.10.30.362822 — bioengineering — Posted on 2020-11-03
3750 Properties of genes encoding transfer RNAs as integration sites for genomic islands and prophages in Klebsiella pneumoniae
Berrios-Pasten, C.; Acevedo, R.; Arros, P.; Varas, M. A.; Wyres, K. L.; Lam, M. M.; Holt, K. E.; Lagos, R.; Marcoleta, A. E.
10.1101/2020.11.02.365908 — genomics — Posted on 2020-11-03
3751 Paraspeckles are constructed as block copolymer micelles through microphase separation
Yamazaki, T.; Yamamoto, T.; Yoshino, H.; Souquere, S.; Nakagawa, S.; Pierron, G.; Hirose, T.
10.1101/2020.11.02.366021 — molecular biology — Posted on 2020-11-03
3754 Forkhead box R1-mediated stress response linked to a case of human microcephaly and brain atrophy
Mota, A.; Hong, R.; Niu, S.-Y.; Bertherat, F.; Wolfe, L.; Malicdan, C. M.; Markello, T. C.; Adams, D. R.; Gahl, W. A.; Cheng, C.; Beffert, U.; Ho, A.
10.1101/2020.11.03.366740 — molecular biology — Posted on 2020-11-03
3755 Control of neurogenic competence in mammalian hypothalamic tanycytes.
Yoo, S.; Kim, J.; Lyu, P.; Hoang, T.; Ma, A.; Trinh, V.; Dai, W.; Jiang, L.; Leavey, P.; Won, J.-K.; Park, S.-H.; Qian, J.; Brown, S. P.; Blackshaw, S.
10.1101/2020.11.02.359992 — neuroscience — Posted on 2020-11-03
3761 RAPPID: a platform of ratiometric bioluminescent sensors for homogeneous immunoassays
Ni, Y.; Rosier, B. J. H. M.; van Aalen, E. A.; Hanckmann, E. T. L.; Biewenga, L.; Makri Pistikou, A.-M.; Timmermans, B.; Vu, C.; Roos, S.; Arts, R.; Li, W.; de Greef, T. F. A.; van Kuppeveld, F. J. M.; Bosch, B.-J.; Merkx, M.
10.1101/2020.10.31.363044 — bioengineering — Posted on 2020-11-03
3762 Genome information processing by the INO80 chromatin remodeler positions nucleosomes
Oberbeckmann, E.; Krietenstein, N.; Niebauer, V.; Wang, Y.; Schall, K.; Moldt, M.; Straub, T.; Rohs, R.; Hopfner, K.-P.; Korber, P.; Eustermann, S.
10.1101/2020.11.03.366690 — biochemistry — Posted on 2020-11-03
3767 The meadow jumping mouse genome and transcriptome suggest mechanisms of hibernation
Cong, Q.; Brem, E. A.; Zhang, J.; Alföldi, J.; Johnson, J.; Karlsson, E. K.; Lindblad-Toh, K.; Malaney, J. L.; Israelsen, W. J.
10.1101/2020.11.02.365791 — genomics — Posted on 2020-11-03
3768 Plastid phylogenomics resolves ambiguous relationships within the orchid family and provides a solid timeframe for biogeography and macroevolution
Serna Sanchez, M. A.; Perez-Escobar, O. A.; Bogarin, D.; Torres, M. F.; Alvarez Yela, A. C.; Arcila Galvis, J. E.; Hall, C. F.; de Barros, F.; Pinheiro, F.; Dodsworth, S.; Chase, M. W.; Antonelli, A.; Arias, T.
10.1101/774018 — evolutionary biology — Posted on 2020-11-03
3770 Neighboring colonies influence uptake of thermotolerant endosymbionts in threatened Caribbean coral recruits
Williamson, O. M.; Allen, C. E.; Williams, D. E.; Johnson, M. W.; Miller, M. W.; Baker, A. C.
10.1101/2020.11.02.360941 — ecology — Posted on 2020-11-03
3772 The smORF-containing gene mille-pattes is required for moulting and Trypanosoma cruzi metacyclogenesis in the Chagas disease vector Rhodnius prolixus
Azevedo, C.; Rodrigues, B.; Alves, S.; Ribeiro, L.; Logullo, C.; Nepomuceno, J.; Roberto-Silva, J.; Mury, F.; Nunes-da-Fonseca, R.
10.1101/2020.10.06.324897 — molecular biology — Posted on 2020-11-03
3773 Characterization of Nonmotor Symptoms in the MitoPark Mouse Model of Parkinson's Disease
Langley, M. R.; Ghaisas, S.; Palanisamy, B.; Ay, M.; Jin, H.; Anantharam, V.; Kanthasamy, A.; Kanthasamy, A.
10.1101/2020.11.02.365874 — neuroscience — Posted on 2020-11-03
3774 ZIKA virus effects on neuroprogenitors are exacerbated by the main pyriproxyfen metabolite via thyroid hormone signaling disruption
Spirhanzlova, P.; Sebillot, A.; Vancamp, P.; Gothie, J.-D.; Le Mevel, S.; Leemans, M.; Wejaphikul, K.; Meima, M.; Mughal, B. B.; Butruille, L.; Roques, P.; Remaud, S.; Fini, J.-B.; Demeneix, B. A.
10.1101/2020.11.03.366468 — neuroscience — Posted on 2020-11-03
3775 MetaGraph: Indexing and Analysing Nucleotide Archives at Petabase-scale
Karasikov, M.; Mustafa, H.; Danciu, D.; Zimmermann, M.; Barber, C.; Ratsch, G.; Kahles, A.
10.1101/2020.10.01.322164 — bioinformatics — Posted on 2020-11-03
3777 Early immune response in mice immunized with a semi-split inactivated vaccine against SARS-CoV-2 containing S protein-free particles and subunit S protein
Petras, M.; Lesny, P.; Musil, J.; Limberkova, R.; Patikova, A.; Jirsa, M.; Krsek, D.; Brezovsky, P.; Koladiya, A.; Vanikova, S.; Mackova, B.; Jirova, D.; Krijt, M.; Lesna, I. K.; Adamkova, V.
10.1101/2020.11.03.366641 — microbiology — Posted on 2020-11-03
3778 The ACE2-binding interface of SARS-CoV-2 Spike inherently deflects immune recognition
Hattori, T.; Koide, A.; Panchenko, T.; Romero, L. A.; Teng, K. W.; Tada, T.; Landau, N. R.; Koide, S.
10.1101/2020.11.03.365270 — biochemistry — Posted on 2020-11-03
3779 Looking for pathways related to COVID-19 phenotypes: Confirmation of pathogenic mechanisms by SARS-CoV-2 - Host interactome.
Messina, F.; Giombini, E.; Montaldo, C.; Sharma, A. A.; Piacentini, M.; Zoccoli, A.; Sekaly, R. P.; Locatelli, F.; Zumla, A.; Maeurer, M.; Capobianchi, M. R.; Lauria, F. N.; Ippolito, G.
10.1101/2020.11.03.366666 — microbiology — Posted on 2020-11-03
3780 Zinc-embedded fabrics inactivate SARS-CoV-2 and influenza A virus
Gopal, V.; Nilsson-Payant, B. E.; French, H.; tenOever, B.; Yung, W.-s.; Hardwick, M.; te Velthuis, A.
10.1101/2020.11.02.365833 — microbiology — Posted on 2020-11-03
3781 Outer membrane lipoprotein DolP interacts with the BAM complex and promotes fitness during envelope stress response
Ranava, D.; Yang, Y.; Orenday-Tapia, L.; Rousset, F.; Turlan, C.; Cui, L.; Morales, V.; Moulin, C.; Munoz, G.; Rech, J.; Caumont-Sarcos, A.; Albenne, C.; Bikard, D.; Ieva, R.
10.1101/2020.09.23.308296 — microbiology — Posted on 2020-11-03
3783 Plasma proteomics reveals tissue-specific cell death and mediators of cell-cell interactions in severe COVID-19 patients
Filbin, M. R.; Mehta, A.; Schneider, A. M.; Kays, K. R.; Guess, J. R.; Gentili, M.; Fenyves, B. G.; Charland, N. C.; Gonye, A. L. K.; Gushterova, I.; Khanna, H. K.; LaSalle, T. J.; Lavin-Parsons, K. M.; Lilley, B. M.; Lodenstein, C. L.; Manakongtreecheep, K.; Margolin, J. D.; McKaig, B. N.; Rojas-Lopez, M.; Russo, B. C.; Sharma, N.; Tantivit, J.; Thomas, M. F.; Gerszten, R. E.; Heimberg, G. S.; Hoover, P. J.; Lieb, D. J.; Lin, B.; Ngo, D.; Pelka, K.; Reyes, M.; Smillie, C. S.; Waghray, A.; Wood, T. E.; Zajac, A. S.; Jennings, L. J.; Grundberg, I.; Bhattacharyya, R. P.; Parry, B. A.; Villani, A
10.1101/2020.11.02.365536 — systems biology — Posted on 2020-11-03
3785 Modelling the active SARS-CoV-2 helicase complex as a basis for structure-based inhibitor design
Berta, D.; Badaoui, M.; Buigues, P. J.; Martino, S. A.; Pisliakov, A.; Elghobashi-Meinhardt, N.; Wells, G.; Harris, S. A.; Frezza, E.; Rosta, E.
10.1101/2020.11.03.366609 — biochemistry — Posted on 2020-11-03
3788 Antiviral activity of plant juices and green tea against SARS-CoV-2 and influenza virus in vitro
Conzelmann, C.; Weil, T.; Gross, R.; Jungke, P.; Frank, B.; Eggers, M.; Mueller, J. A.; Muench, J.
10.1101/2020.10.30.360545 — microbiology — Posted on 2020-11-03
3790 Rapid development of SARS-CoV-2 receptor binding domain-conjugated nanoparticle vaccine candidate
Kang, Y.-F.; Sun, C.; Zhuang, Z.; Yuan, R.-Y.; Zheng, Q.-B.; Zhou, P.-P.; Li, J.-P.; Chen, X.-C.; Zhang, X.; Yu, X.-H.; Kong, X.-W.; Zhu, Q.-Y.; Xu, M.; Zhong, N.-S.; Zeng, Y.-X.; Feng, G.-K.; Ke, C.-W.; Zhao, J.-C.; Zeng, M.-S.
10.1101/2020.11.03.366138 — microbiology — Posted on 2020-11-03
3791 Identification of Cross-Reactive CD8+ T Cell Receptors with High Functional Avidity to a SARS-CoV-2 Immunodominant Epitope and Its Natural Mutant Variants
Hu, C.; Shen, M.; Han, X.; Chen, Q.; Li, L.; Chen, S.; Zhang, J.; Gao, F.; Wang, W.; Wang, Y.; Li, T.; Li, S.; Huang, J.; Wang, J.; Zhu, J.; Chen, D.; Wu, Q.; Tao, K.; Pang, D.; Jin, A.
10.1101/2020.11.02.364729 — immunology — Posted on 2020-11-03
3792 Action enhances predicted touch
Thomas, E. R.; Yon, D.; de Lange, F. P.; Press, C.
10.1101/2020.03.26.007559 — neuroscience — Posted on 2020-11-03
3793 Classical oncogene family Myc defines unappreciated distinct lineage states of small cell lung cancer
Patel, A. S.; Yoo, S.; Kong, R.; Sato, T.; Sinha, A.; Bao, L.; Fridrikh, M.; Emoto, K.; Nudelman, G.; Powell, C. A.; Beasley, M. B.; Zhu, J.; Watanabe, H.
10.1101/852939 — cancer biology — Posted on 2020-11-03
3795 Cross-Platform Validation of Neurotransmitter Release Impairments in Schizophrenia Patient-Derived NRXN1-Mutant Neurons
Pak, C.; Danko, T.; Mirabella, V. R.; Wang, J.; Zhang, X.; Ward, T.; Grieder, S.; Vangipuram, M.; Huang, Y.-W. A.; Liu, Y.; Jin, K.; Dexheimer, P.; Bardes, E.; Mitelpunkt, A.; Ma, J.; McLachlan, M.; Moore, J. C.; Urban, A. E.; Dage, J. L.; Swanson, B. J.; Aronow, B. J.; Pang, Z. P.; Levinson, D. F.; Wernig, M.; Sudhof, T. C.
10.1101/2020.11.03.366617 — neuroscience — Posted on 2020-11-03
3796 Alcohol dependence activates ventral tegmental area projections to central amygdala in male mice and rats
Avegno, E. M.; Kasten, C. R.; Snyder, W. B.; Kelley, L. K.; Lobell, T. D.; Templeton, T. J.; Constans, M.; Wills, T. A.; Middleton, J. W.; Gilpin, N. W.
10.1101/2020.11.02.365445 — neuroscience — Posted on 2020-11-03
3797 Assessing uncertainty in connective field estimations from resting state fMRI activity
Invernizzi, A.; Gravel, N. G.; Haak, K. V.; Renken, R. J.; Cornelissen, F. W.
10.1101/2020.11.02.365452 — neuroscience — Posted on 2020-11-03
3798 eNOS-dependent S-nitrosylation of the NF-κB subunit p65 has neuroprotective effects
Caviedes, A.; Maturana, B.; Corvalan, K.; Engler, A.; Gordillo, F.; Varas-Godoy, M.; Smalla, K.-H.; Batiz, L. F.; Lafourcade, C. A.; Kaehne, T.; Wyneken, U.
10.1101/2020.02.04.932772 — neuroscience — Posted on 2020-11-03
3799 Directed evolution for improved total secretory protein production in Escherichia coli
Gonzalez-Perez, D.; Ratcliffe, J.; Tan, S. K.; Wong, M. C. M.; Yee, Y. P.; Nyabadza, N.; Xu, J.-H.; Wong, T. S.; Tee, K. L.
10.1101/2020.11.03.366773 — synthetic biology — Posted on 2020-11-03
3800 Mechanisms underlying divergent responses of genetically distinct macrophages to IL-4
Hoeksema, M. A.; Shen, Z.; Holtman, I. R.; Zheng, A.; Spann, N.; Cobo, I.; Gymrek, M.; Glass, C. K.
10.1101/2020.11.02.365742 — genomics — Posted on 2020-11-03
3802 A global indicator of utilised wildlife populations: regional trends and the impact of management
McRae, L.; Freeman, R.; Geldmann, J.; Moss, G. B.; Kjaer-Hansen, L.; Burgess, N. D.
10.1101/2020.11.02.365031 — ecology — Posted on 2020-11-03
3807 Computation of the electroencephalogram (EEG) from network models of point neurons
Martinez Canada, P.; Ness, T. V.; Einevoll, G. T.; Fellin, T.; Panzeri, S.
10.1101/2020.11.02.364802 — neuroscience — Posted on 2020-11-03
3810 Signature morpho-electric, transcriptomic, and dendritic properties of extratelencephalic-projecting human layer 5 neocortical pyramidal neurons
Kalmbach, B.; Hodge, R.; Jorstad, N.; Owen, S.; Bakken, T.; de Frates, R.; Yanny, A. M.; Dalley, R.; Graybuck, L.; Daigle, T.; Radaelli, C.; Mallory, M.; McGraw, M.; Dee, N.; Nicovich, P.; Keene, D.; Gwinn, R.; Silbergeld, D.; Cobbs, C.; Ojemann, J.; Ko, A.; Patel, A.; Ellenbogen, R.; Sorensen, S.; Smith, K.; Zeng, H.; Tasic, B.; Koch, C.; Lein, E.; Ting, J.
10.1101/2020.11.02.365080 — neuroscience — Posted on 2020-11-03
3811 Associations between Early Midlife Lifestyle Behaviors, Young Adult Cognitive Reserve and Advanced Predicted Brain Age in Late Midlife
Franz, C. E.; Hatton, S. N.; Elman, J. A.; Warren, T.; Gillespie, N. A.; Whitsel, N. A.; Puckett, O. K.; Dale, A. M.; Eyler, L. T.; Fennema-Notestine, C.; Hagler, D. J.; Hauger, R. L.; McKenzie, R.; Neale, M. C.; Panizzon, M. S.; Pearce, R. C.; Reynolds, C. R.; Sanderson-Cimino, M.; Toomey, R.; Tu, X.; Xian, H.; Lyons, M. J.; Kremen, W.
10.1101/2020.11.02.362780 — neuroscience — Posted on 2020-11-03
3813 Learning to live with Dale's principle: ANNs with separate excitatory and inhibitory units
Cornford, J.; Kalajdzievski, D.; Leite, M.; Lamarquette, A.; Kullmann, D. M.; Richards, B. A.
10.1101/2020.11.02.364968 — neuroscience — Posted on 2020-11-03
3815 Navigating through chemical space and evolutionary time across the Australian continent in plant genus Eremophila
Gericke, O.; Fowler, R. M.; Heskes, A. M.; Bayly, M.; Semple, S. J.; Ndi, C. P.; Staerk, D.; Loland, C. J.; Murphy, D. J.; Buirchell, B. J.; Moller, B. L.
10.1101/2020.11.02.364471 — plant biology — Posted on 2020-11-03
3816 Machine learning enabled phenotyping for GWAS and TWAS of WUE traits in 869 field-grown sorghum accessions
Ferguson, J.; Fernandes, S.; Monier, B.; Miller, N. D.; Allan, D.; Dmitrieva, A.; Schmuker, P.; Lozano, R.; Valluru, R.; Buckler, E. S.; Gore, M. A.; Brown, P.; Spalding, E. P.; Leakey, A.
10.1101/2020.11.02.365213 — plant biology — Posted on 2020-11-03
3817 RESTORING CONNEXIN-36 FUNCTION IN DIABETOGENIC ENVIRONMENTS PRECLUDES MOUSE AND HUMAN ISLET DYSFUNCTION
St Clair, J. R.; Westacott, M. J.; Farnsworth, N. L.; Kravets, V.; Schleicher, W. E.; Miranda, J. G.; Heintz, A.; Ludin, N. W. F.; Benninger, R. K.
10.1101/2020.11.03.366179 — biophysics — Posted on 2020-11-03
3818 Runcer-Necromancer: A Method To Rescue Data From An Interrupted Run On MGISEQ-2000
Pavlova, A.; Belova, V.; Afasizhev, R.; Bulusheva, I.; Rebrikov, D.; Korostin, D.
10.1101/2020.11.02.364588 — bioinformatics — Posted on 2020-11-03
3819 Immunopeptidomics for Dummies: Detailed Experimental Protocols and Rapid, User-Friendly Visualization of MHC I and II Ligand Datasets with MhcVizPipe
Sirois, I.; Caron, E.; Kovalchik, K. A.; Wessling, L.; Saab, F.; Ma, Q.; Despault, J.; Kubiniok, P.; Hamelin, D.; Faridi, P.; Li, C.; Purcell, A. W.; Tognetti, M.; Reiter, L.; Bruderer, R.; Lanoix, J.; Bonneil, E.; Courcelles, M.; Thibault, P.
10.1101/2020.11.02.360958 — bioinformatics — Posted on 2020-11-03
3825 Novel incursion of a highly pathogenic avian influenza subtype H5N8 virus in the Netherlands, October 2020
Beerens, N.; Heutink, R.; Harders, F.; Roose, M.; Pritz-Verschuren, S.; Germeraad, E.; Engelsma, M.
10.1101/2020.11.03.361634 — microbiology — Posted on 2020-11-03
3826 COVID-19 cytokines and the hyperactive immune response: Synergism of TNF-α and IFN-γ in triggering inflammation, tissue damage, and death
Karki, R.; Sharma, B. R.; Tuladhar, S.; Williams, E. P.; Zalduondo, L.; Samir, P.; Zheng, M.; Sundaram, B.; Banoth, B.; Malireddi, R. K. S.; Schreiner, P.; Neale, G.; Vogel, P.; Webby, R.; Jonsson, C. B.; Kanneganti, T.-D.
10.1101/2020.10.29.361048 — immunology — Posted on 2020-11-03
3829 The vesicular release probability sets the strength of individual Schaffer collateral synapses
Duerst, C. D.; Wiegert, J. S.; Schulze, C.; Helassa, N.; Torok, K.; Oertner, T. G.
10.1101/2020.08.02.232850 — neuroscience — Posted on 2020-11-03
3830 Kinetic model of small RNA-mediated regulation suggests that a small RNA can regulate co-transcriptionally
Reyer, M. A.; Chennakesavalu, S.; Heideman, E. M.; Ma, X.; Bujnowska, M.; Hong, L.; Dinner, A. R.; Vanderpool, C. K.; Fei, J.
10.1101/2020.11.03.365106 — biophysics — Posted on 2020-11-03
3831 Microfluidic Antibody Affinity Profiling for In-Solution Characterisation of Alloantibody - HLA Interactions in Human Serum
Schneider, M. M.; Scheidt, T.; Priddey, A. J.; Xu, C. K.; Hu, M.; Devenish, S. R. A.; Meisl, G.; Dobson, C. M.; Kosmoliaptsis, V.; Knowles, T. P. J.
10.1101/2020.09.14.296442 — biophysics — Posted on 2020-11-03
3832 Structure of the endocytic adaptor complex reveals the basis for efficient membrane anchoring during clathrin-mediated endocytosis
Lizarrondo, J.; Klebl, D. P.; Niebling, S.; Abella, M.; Schroer, M. A.; Mertens, H. D. T.; Veith, K.; Svergun, D. I.; Skruzny, M.; Sobott, F.; Muench, S.; Garcia-Alai, M. M.
10.1101/2020.11.03.364851 — biophysics — Posted on 2020-11-03
3834 Selection on ancient variations drives the adaptive radiation of Metrosideros across the Hawaiian archipelago
Choi, J. Y.; Dai, X.; Peng, J. Z.; Rughani, P.; Hickey, S.; Harrington, E.; Juul, S.; Ayroles, J.; Purugganan, M.; Stacy, E.
10.1101/2020.11.03.354068 — evolutionary biology — Posted on 2020-11-03
3837 Dichloroacetate reverses sepsis-induced hepatic metabolic dysfunction
Mainali, R.; Zabalwi, M.; Long, D.; Buechler, N.; Quillen, E.; Key, C.-C.; Zhu, X.; Parks, J.; Furdui, C.; Stacpoole, P.; Martinez, J.; McCall, C. E.; Quinn, M. A.
10.1101/2020.06.09.142430 — immunology — Posted on 2020-11-03
3838 Citric Acid Water as an Alternative to Water Restriction for High-Yield Mouse Behavior
Urai, A. E.; Aguillon-Rodriguez, V.; Laranjeira, I.; Cazettes, F.; The International Brain Laboratory, ; Mainen, Z. F.; Churchland, A. K.
10.1101/2020.03.02.973016 — neuroscience — Posted on 2020-11-03
3839 A fine-tuned interplay of three A. thaliana UDP glucosyltransferases orchestrates salicylic acid homeostasis
Bauer, S.; Georgii, E.; Lange, B.; Maksym, R. P.; Janowski, R.; Geist, B.; Schaeffner, A. R.
10.1101/2020.11.02.365221 — plant biology — Posted on 2020-11-03
3841 Oxylipin metabolism is controlled by mitochondrial b-oxidation during bacterial inflammation.
Misheva, M.; Kotzamanis, K.; Davies, L.; Tyrrell, V.; Rodrigues, P.; Benavides, G.; Christine, H.; Murphy, R.; Kennedy, P.; Taylor, P.; Rosas, M.; Jones, S.; Deshpande, S.; Andrews, R.; Czubala, M.; Gurney, M.; Aldrovandi, M.; Meckelmann, S.; Ghazal, P.; Darley-Usmar, V.; White, D.; O'Donnell, V.
10.1101/2020.08.17.252007 — biochemistry — Posted on 2020-11-03
3845 Simvastatin Therapy Attenuates Memory Deficits that Associate to Brain Monocyte Infiltration in Chronic Hypercholesterolemic ApoE-/- Mice
Don-Doncow, N.; Matthes, F.; Matuskova, H.; Rattik, S.; Vanherle, L.; Kragh Petersen, S.; Hartlova, A.; Meissner, A.
10.1101/2020.05.15.098236 — physiology — Posted on 2020-11-03
3846 Loss of the RNA helicase Dhx15 impairs endothelial energy metabolism, lymphatic drainage and tumor metastasis in mice
Ribera, J.; Portoles, I.; Cordoba-Jover, B.; Rodriguez-Vita, J.; Casals, G.; Gonzalez-de la Presa, B.; Graupera, M.; Soria, G.; Tudela, R.; Esteve-Codina, A.; Espadas, G.; Sabido, E.; Jimenez, W.; Sessa, W. C.; Morales-Ruiz, M.
10.1101/2020.11.03.366286 — cell biology — Posted on 2020-11-03
3847 GATA3 and MDM2 are synthetic lethal in estrogen receptor-positive breast cancers
Bianco, G.; Coto Llerena, M.; Gallon, J.; Taha-Mehlitz, S.; Kancherla, V.; Konantz, M.; Srivatsa, S.; Montazeri, H.; Panebianco, F.; De Menna, M.; Paradiso, V.; Ercan, C.; Dahmani, A.; Montaudon, E.; Beerenwinkel, N.; Kruithof-de Julio, M.; Terracciano, L.; Lengerke, C.; Bidard, F.-C.; Jeselsohn, R.; Marangoni, E.; Ng, C. K.; Piscuoglio, S.
10.1101/2020.05.18.101998 — cancer biology — Posted on 2020-11-03
3851 Fast-Bonito: A Faster Basecaller for Nanopore Sequencing
Xu, Z.; Mai, Y.; Liu, D.; He, W.; Lin, X.; Xu, C.; Zhang, L.; Meng, X.; Mafofo, J.; Zaher, W. A.; Li, Y.; Qiao, N.
10.1101/2020.10.08.318535 — bioinformatics — Posted on 2020-11-03
3853 Direct Quantification of in vivo Mutagenesis and Carcinogenesis Using Duplex Sequencing
Valentine, C. C.; Young, R. R.; Fielden, M. R.; Kulkarni, R.; Williams, L. N.; Li, T.; Minocherhomji, S.; Salk, J. J.
10.1101/2020.06.28.176685 — genomics — Posted on 2020-11-03
3854 The Pleistocene species pump past its prime: evidence from European butterfly sister species
Ebdon, S.; Laetsch, D. R.; Dapporto, L.; Hayward, A.; Ritchie, M. G.; Dinca, V.; Vila, R.; Lohse, K.
10.1101/2020.09.04.282962 — evolutionary biology — Posted on 2020-11-03
3855 Differential effects of prediction and adaptation along the cortical hierarchy during deviance processing
Schlossmacher, I.; Dilly, J.; Protmann, I.; Hofmann, D.; Dellert, T.; Roth-Paysen, M.-L.; Moeck, R.; Bruchmann, M.; Straube, T.
10.1101/2020.10.19.339234 — neuroscience — Posted on 2020-11-03
3856 LincRNA sequences are biased to counteract translation
Brümmer, A.; Dreos, R.; Marques, A. C.; Bergmann, S.
10.1101/737890 — genomics — Posted on 2020-11-03
3857 More rule than exception: Parallel evidence of ancient migrations in grammars and genomes of Finno-Ugric speakers
Santos, P.; Gonzalez-Fortes, G.; Trucchi, E.; Ceolin, A.; Cordoni, G.; Guardiano, C.; Longobardi, G.; Barbujani, G.
10.1101/2020.11.02.364521 — genomics — Posted on 2020-11-03
3858 Experimental evolution of adaptive divergence under varying degrees of gene flow
Tusso, S.; Nieuwenhuis, B. P. S.; Weissensteiner, B.; Immler, S.; Wolf, J. B. W.
10.1101/2020.11.02.364695 — evolutionary biology — Posted on 2020-11-03
3859 Extensive MET alterations confer clinical response to MET inhibitors in gliomas
Zhao, Z.; Chen, J.; Bao, Z.; Chai, R.; Zhang, K.-n.; Wu, L.; Liu, H.; Mu, Q.; Hu, H.; Zeng, F.; Wang, Z.; Li, G.; Chang, Y.; Wang, Q.; Wu, F.; Zhang, Y.; Liu, Y.; Zhang, W.; Kang, C.; Wang, J.; Tao, R.; Wang, Q.; Jiang, T.
10.1101/2020.11.02.364711 — neuroscience — Posted on 2020-11-03
3860 crispr2vec: Machine Learning Model Predicts Off-Target Cuts of CRISPR systems
Basu Trivedi, T.; Boger, R.; Kamath, G.; Evangelopoulos, G.; Cate, J.; Doudna, J.; Hidary, J.
10.1101/2020.10.28.359885 — synthetic biology — Posted on 2020-11-03
3862 A Two-Step Bioreactor for Lung Recellularization
Young, B. M.; Antczak, L.-A. M.; Shankar, K.; Heise, R. L.
10.1101/2020.11.02.360792 — bioengineering — Posted on 2020-11-02
3865 Liquid chalk is an antiseptic against SARS-CoV-2 and influenza A respiratory viruses
McAuley, J. L.; Deerain, J. M.; Hammersla, W.; Aktepe, T. E.; Purcell, D. J. F.; Mackenzie, J.
10.1101/2020.11.02.364661 — microbiology — Posted on 2020-11-02
3867 Extensive MET alterations confer clinical response to MET inhibitors in gliomas
Zhao, Z.; Chen, J.; Bao, Z.; Chai, R.; Zhang, K.-n.; Wu, L.; Liu, H.; Mu, Q.; Hu, H.; Zeng, F.; Wang, Z.; Li, G.; Chang, Y.; Wang, Q.; Wu, F.; Zhang, Y.; Liu, Y.; Zhang, W.; Kang, C.; Wang, J.; Tao, R.; Wang, Q.; Jiang, T.
10.1101/2020.11.02.364711 — neuroscience — Posted on 2020-11-02
3871 Engineered Red Blood Cells Carrying PCSK9 Inhibitors Persistently Lower LDL and Prevent Obesity
Deshycka, R.; Sudaryo, V.; Huang, N.-J.; Xie, Y.; Smeding, L. Y.; Choi, M. K.; Ploegh, H.; Lodish, H.; Pishesha, N.
10.1101/2020.11.02.364620 — bioengineering — Posted on 2020-11-02
3874 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-02
3875 Focus-tunable microscope for imaging small neuronal processes in freely moving animals
Bagramyan, A.; Tabourin, L.; Rastqar, A.; Karimi, N.; Bretzner, F.; Galstian, T.
10.1101/2020.10.31.363507 — neuroscience — Posted on 2020-11-02
3876 YB-1 IS REQUIRED FOR THE GENESIS AND METASTATIC CAPACITY OF HUMAN BREAST CANCER
Lefort, S.; El-Naggar, A.; Tan, S.; Colborne, S.; Negri, G. L.; Pellacani, D.; Hirst, M.; Gusterson, B.; Morin, G. B.; Sorensen, P. H.; Eaves, C. J.
10.1101/372524 — cancer biology — Posted on 2020-11-02
3877 Lipogenesis and innate immunity in hepatocellular carcinoma cells reprogrammed by an isoenzyme switch of hexokinases
Perrin-Cocon, L.; Vidalain, P.-O.; Jacquemin, C.; Aublin-Gex, A.; Olmstead, K.; Panthu, B.; Rautureau, G. J. P.; Andre, P.; Nyczka, P.; Hutt, M.-T.; Amoedo, N.; Rossignol, R.; Filipp, F. V.; Lotteau, V.; Diaz, O.
10.1101/2020.03.13.973321 — cancer biology — Posted on 2020-11-02
3880 Trade-offs between risks of predation and starvation in larvae make the shelf break an optimal spawning location for Atlantic Bluefin tuna
Shropshire, T. A.; Morey, S. L.; Chassignet, E. P.; Karnauskas, M.; Coles, V. J.; Malca, E.; Laiz-Carrion, R.; Fiksen, O.; Reglero, P.; Shiroza, A.; Maria Quintanilla Hervas, J.; Gerard, T.; Lamkin, J.; Stukel, M. R.
10.1101/2020.11.01.363465 — ecology — Posted on 2020-11-02
3882 DNAJB12 and Hsp70 Facilitate the Conformation Specific Degradation of Arrested N1303K-CFTR Intermediates by ERQC-Autophagy
He, L.; Kennedy, A. S.; Houck, S.; Aleksandrov, A. A.; Quinney, N. L.; Gentzsch, M.; Cholon, D.; Randell, S. H.; Ren, H. Y.; Cyr, D. M.
10.1101/2020.10.28.358580 — cell biology — Posted on 2020-11-02
3883 Breastmilk-promoted bifidobacteria produce aromatic lactic acids in the infant gut
Laursen, M. F.; Sakanaka, M.; von Burg, N.; Mörbe, U.; Andersen, D.; Moll, J. M.; Pekmez, C. T.; Rivollier, A.; Michaelsen, K. F.; Molgaard, C.; Lind, M. V.; Dragsted, L. O.; Katayama, T.; Frandsen, H. L.; Vinggaard, A. M.; Bahl, M. I.; Brix, S.; Agace, W.; Licht, T. R.; Roager, H. M.
10.1101/2020.01.22.914994 — microbiology — Posted on 2020-11-02
3884 Microbiota functional activity biosensors for characterizing nutrient utilization in vivo
Wesener, D. A.; Beller, Z. W.; Peters, S. L.; Rajabi, A.; Dimartino, G.; Giannone, R. J.; Hettich, R. L.; Gordon, J. I.
10.1101/2020.11.02.362798 — microbiology — Posted on 2020-11-02
3885 Neutrophils encompass a regulatory subset suppressing T cells in apparently healthy cattle and mice
Rambault, M.; Doz-Deblauwe, E.; Le Vern, Y.; Carreras, F.; Cunha, P.; Germon, P.; Rainard, P.; Winter, N.; Remot, A.
10.1101/2020.11.02.364885 — immunology — Posted on 2020-11-02
3888 Timing of readiness potentials reflect a decision-making process in the human brain
Lui, K. K.; Nunez, M. D.; Cassidy, J. M.; Vandekerckhove, J.; Cramer, S. C.; Srinivasan, R.
10.1101/338806 — neuroscience — Posted on 2020-11-02
3889 Single-molecule studies of conformational states and dynamics in the ABC importer OpuA
Tassis, K.; Vietrov, R.; Koning, M. d.; de Boer, M.; Gouridis, G.; Cordes, T.
10.1101/2020.08.07.241463 — biophysics — Posted on 2020-11-02
3893 Mitochondrial copper and phosphate transporter specificity was defined early in the evolution of eukaryotes
Zhu, X.; Boulet, A.; Buckley, K. M.; Phillips, C. B.; Gammon, M. G.; Oldfather, L. E.; Moore, S. A.; Leary, S. C.; Cobine, P. A.
10.1101/2020.11.02.365692 — evolutionary biology — Posted on 2020-11-02
3894 Single cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination
Mayere, C.; Neirijnck, Y.; Sararols, P.; Rands, C.; Stevant, I.; Kühne, F.; Chassot, A.-A.; Chaboissier, M.-C.; Dermitzakis, E.; Nef, S.
10.1101/747279 — developmental biology — Posted on 2020-11-02
3896 Reduced ech-6 Expression Attenuates Fat-induced Premature Aging in C. elegans
Liu, Y. J.; Gao, A. W.; Smith, R. L.; Janssens, G. E.; Panneman, D. M.; Jongejan, A.; van Weeghel, M.; Vaz, F. M.; Silvestrini, M. J.; Lapierre, L. R.; MacInnes, A. W.; Houtkooper, R. H.
10.1101/2020.11.02.364760 — cell biology — Posted on 2020-11-02
3897 Creld2 function during unfolded protein response is essential for liver metabolism homeostasis
Kern, P.; Balzer, N. R.; Bender, F.; Frolov, A.; Wunderling, K.; Sowa, J.-P.; Bonaguro, L.; Ulas, T.; Thiele, C.; Schultze, J. L.; Canbay, A.; Bauer, R.; Mass, E.
10.1101/2020.01.28.923136 — molecular biology — Posted on 2020-11-02
3898 Production of nonulosonic acids in the extracellular polymeric substances of Candidatus Accumulibacter phosphatis
Tomas-Martinez, S.; Kleikamp, H. B. C.; Neu, T. R.; Pabst, M.; Weissbrodt, D. G.; van Loosdrecht, M. C. M.; Lin, Y.
10.1101/2020.11.02.365007 — microbiology — Posted on 2020-11-02
3902 Developmental effects of oxytocin neurons on social affiliation and processing of social information
Nunes, A. R.; Gliksberg, M.; Varela, S. A. M.; Teles, M.; Wircer, E.; Blechman, J.; Petri, G.; Levkowitz, G.; Oliveira, R. F.
10.1101/2020.10.08.330993 — neuroscience — Posted on 2020-11-02
3903 Imaging stable isotope labelling kinetics (iSILK) for following spatial Aβ plaque aggregation dynamics in evolving Alzheimers disease pathology
Michno, W.; Stringer, K. M.; Enzlein, T.; Passarelli, M.; Escrig, S.; Blennow, K.; Zetterberg, H.; Meibom, A.; Hopf, C.; Edwards, F. A.; Hanrieder, J.
10.1101/2020.10.12.335828 — neuroscience — Posted on 2020-11-02
3904 RTP801 REGULATES MOTOR CORTEX SYNAPTIC TRANSMISSION AND LEARNING
Perez-Sisques, L.; Martin-Flores, N.; Masana, M.; Solana, J.; Llobet, A.; Romani-Aumedes, J.; Canal, M.; Campoy, G.; Garcia, E.; Sanchez, N.; Fernandez, S.; Gilbert, J. P.; Rodriguez, M. J.; Man, H.; Feinstein, E.; Williamson, D.; Soto, D.; Gasull, X.; Alberch, J.; Malagelada, C.
10.1101/2020.10.15.340851 — neuroscience — Posted on 2020-11-02
3905 Transient Maternal IL-6 boosts glutamatergic synapses and disrupts hippocampal connectivity in the offspring
Mirabella, F.; Desiato, G.; Mancinelli, S.; Fossati, G.; Rasile, M.; Morini, R.; Markicevic, M.; Grimm, C.; amegandjin, C.; Termanini, A.; Peano, C.; Kunderfranco, P.; DiCristo, G.; Zerbi, V.; Lodato, S.; Menna, E.; Matteoli, M.; Pozzi, D.
10.1101/2020.11.02.364356 — neuroscience — Posted on 2020-11-02
3907 ATF-4 and hydrogen sulfide signalling mediate longevity from inhibition of translation or mTORC1
Statzer, C.; Venz, R.; Bland, M.; Robida-Stubbs, S.; Meng, J.; Patel, K.; Emsley, R.; Petrovic, D.; Liu, P.; Morantte, I.; Haynes, C.; Filipovic, M.; Mair, W. B.; Longchamp, A.; Blackwell, T. K.; Ewald, C. Y.
10.1101/2020.11.02.364703 — physiology — Posted on 2020-11-02
3908 NOVEL NUCLEAR ROLE OF HDAC6 IN PROGNOSIS AND THERAPEUTIC TARGET FOR COLORECTAL CANCER
Garcia-Dominguez, D. J.; Hontecillas-Prieto, L.; Kaliszczak, M.; He, M.; Burguillos, M.; El Bekay, R.; Abdul-Salam, V. B.; Combiz, K.; Shah, K.; O'Neill, k.; de Alava, E.; Silver, A.; Syed, N.; Aboagye, E. O.; Hajji, N.
10.1101/2020.11.02.356121 — cancer biology — Posted on 2020-11-02
3909 Multi-modal Nonlinear Optical and Thermal Imaging Platform for Label-Free Characterization of Biological Tissue
Adams, W. R.; Mehl, B.; Lieser, E.; Wang, M.; Patton, S.; Throckmorton, G. A.; Jenkins, J. L.; Ford, J. B.; Gautam, R.; Brooker, J.; Jansen, E. D.; Mahadevan-Jansen, A.
10.1101/2020.04.06.023820 — biophysics — Posted on 2020-11-02
3910 Hindbrain neuropore tissue geometry determines asymmetric cell-mediated closure dynamics
Maniou, E.; Staddon, M.; Marshall, A.; Greene, N.; Copp, A.; Banerjee, S.; Galea, G.
10.1101/2020.11.02.364513 — biophysics — Posted on 2020-11-02
3914 Yeast Ssd1 is a non-enzymatic member of the RNase II family with an alternative RNA recognition interface
Bayne, R. A.; Jayachandran, U.; Kasprowicz, A.; Bresson, S.; Tollervey, D.; Wallace, E. W. J.; Cook, A. G.
10.1101/2020.10.22.350314 — biochemistry — Posted on 2020-11-02
3918 Relative time constraints improve molecular dating
Szollosi, G. J.; Hoehna, S.; Williams, T. A.; Schrempf, D.; Daubin, V.; Boussau, B.
10.1101/2020.10.17.343889 — evolutionary biology — Posted on 2020-11-02
3919 Correction of a Factor VIII genomic inversion with designer-recombinases
Lansing, F.; Mukhametzyanova, L.; Rojo-Romanos, T.; Iwasawa, K.; Kimura, M.; Paszkowski-Rogacz, M.; Karpinski, J.; Grass, T.; Sonntag, J.; Schneider, P. M.; Günes, C.; Hoersten, J.; Schmitt, L. T.; Rodriguez-Muela, N.; Knöfler, R.; Takebe, T.; Buchholz, F.
10.1101/2020.11.02.328013 — molecular biology — Posted on 2020-11-02
3920 Common transcriptional programme of liver fibrosis in mouse genetic models and humans
Blagotinsek Cokan, K.; Urlep, Z.; Moskon, M.; Mraz, M.; Kong, X. Y.; Eskild, W.; Rozman, D.; Juvan, P.; Rezen, T.
10.1101/2020.11.02.364901 — molecular biology — Posted on 2020-11-02
3921 Homeodomain protein 1 is an essential regulator of gene expression during sexual differentiation of malaria parasites
Campelo Morillo, R.; Tong, X.; Xie, W.; Lenz, T.; Batugedara, G.; Tabassum, N.; Orchard, L. M.; Daher, W.; Patel, D.; Noble, W. S.; Llinas, M.; Le Roch, K. G.; Kafsack, B. F. C.
10.1101/2020.10.26.352583 — microbiology — Posted on 2020-11-02
3922 IL-12 signaling promotes TET2-mediated DNA demethylation during CD8 T cell effector differentiation
Zebley, C.; Abdelsamed, H.; Ghoneim, H.; Alli, S.; Haydar, D.; Harris, T.; Mcgargill, M.; Krenciute, G.; Youngblood, B.
10.1101/2020.11.02.365148 — immunology — Posted on 2020-11-02
3923 An epithelial Nfkb2 pathway exacerbates intestinal inflammation by supplementing latent RelA dimers to the canonical NF-κB module
Chawla, M.; Mukherjee, T.; Deka, A.; Chatterjee, B.; Sarkar, U. A.; Singh, A. K.; Kedia, S.; Banoth, B.; Biswas, S. K.; Ahuja, V.; Basak, S.
10.1101/2020.11.02.365890 — immunology — Posted on 2020-11-02
3924 NLRC5 regulates expression of MHC-I and provides a target for anti-tumor immunity in transmissible cancers
Ong, C. E. B.; Patchett, A. L.; Darby, J. M.; Chen, J.; Liu, G.-S.; Lyons, A. B.; Woods, G. M.; Flies, A. S.
10.1101/2020.09.06.274720 — immunology — Posted on 2020-11-02
3925 The G protein-Coupled Metabotropic Glutamate Receptor 1 controls neuronal macroautophagy
Donoso, M.; Speranza, L.; Kalinowska, M.; Castillo, C.; De Sanctis, C.; Francesconi, A.
10.1101/2020.11.02.365783 — neuroscience — Posted on 2020-11-02
3926 Control of neurogenic competence in mammalian hypothalamic tanycytes.
Yoo, S.; Kim, J.; Lyu, P.; Hoang, T.; Ma, A.; Trinh, V.; Dai, W.; Jiang, L.; Leavey, P.; Won, J.-K.; Park, S.-H.; Qian, J.; Brown, S. P.; Blackshaw, S.
10.1101/2020.11.02.359992 — neuroscience — Posted on 2020-11-02
3929 The timing and impact of psychiatric, cognitive and motor manifestations of Huntington's disease
McAllister, B.; Gusella, J. F.; Landwehrmeyer, G. B.; Lee, J.-M.; MacDonald, M. E.; Orth, M.; Rosser, A. E.; Williams, N. M.; REGISTRY Investigators of the European Huntington's disease network, ; Holmans, P.; Jones, L.; Massey, T. H.
10.1101/2020.05.26.116798 — neuroscience — Posted on 2020-11-02
3930 Loss of a plant receptor kinase recruits beneficial rhizosphere-associated Pseudomonas
Song, Y.; Wilson, A. J.; Zhang, X.-C.; Thoms, D.; Sohrabi, R.; Song, S.; Geissmann, Q.; Liu, Y.; Walgren, L.; He, S. Y.; Haney, C. H.
10.1101/2020.11.02.364109 — plant biology — Posted on 2020-11-02
3931 Ivermectin reduces coronavirus infection in vivo: a mouse experimental model
Arevalo, A. P.; Pagotto, R.; Porfido, J.; Daghero, H.; Segovia, M.; Yamasaki, K.; Varela, B.; Hill, M.; Verdes, J. M.; Duhalde Vega, M.; Bollati-Fogolin, M.; Crispo, M.
10.1101/2020.11.02.363242 — pathology — Posted on 2020-11-02
3932 The epithelial splicing regulator ESRP2 is epigenetically repressed by DNA hypermethylation in Wilms tumour and acts as a tumour suppressor
Legge, D.; Ling, L.; Moriarty, W.; Lee, D.; Szemes, M.; Zahed, A.; Panousopoulus, L.; Chung, W. Y.; Aghabi, Y.; Barrett, J.; Williams, R.; Pritchard-Jones, K.; Malik, K.; Oltean, S.; Brown, K. W.
10.1101/2020.11.02.364570 — cancer biology — Posted on 2020-11-02
3933 Adipose Triglyceride Lipase is needed for homeostatic control of Sterol Element-Binding Protein-1c driven hepatic lipogenesis
Wieser, B. I.; Pena de la Sancha, P.; Schauer, S.; Reicher, H.; Sattler, W.; Breinbauer, R.; Schweiger, M.; Espenshade, P. J.; Zechner, R.; Hoefler, G.; Vesely, P. W.
10.1101/2020.11.02.363440 — biochemistry — Posted on 2020-11-02
3940 Non-invasive, label-free optical analysis to detect aneuploidy within the inner cell mass of the preimplantation embryo
Tan, C. Y.; Mahbub, S. B.; Campugan, C. A.; Campbell, J. M.; Habibalahi, A.; Chow, D. J. X.; Mustafa, S.; Goldys, E. M.; Dunning, K. R.
10.1101/2020.11.01.364133 — cell biology — Posted on 2020-11-02
3943 Small-scale commercial chicken production: A risky business for farmers in the Mekong Delta of Vietnam
Truong, B. D.; Van Cuong, N.; Phu, D. H.; Dung, N. T. T.; Kiet, B. T.; Rushton, J.; Carrique-Mas, J.
10.1101/2020.11.02.364281 — microbiology — Posted on 2020-11-02
3944 Robust SARS-CoV-2-specific T-cell immunity is maintained at 6 months following primary infection
Zuo, J.; Dowell, A.; Pearce, H.; Verma, K.; Long, H.; Begum, J.; Aiano, F.; Amin-Chowdhury, Z.; Hallis, B.; Stapley, L.; Borrow, R.; Linley, E.; Ahmad, S.; Parker, B.; Horsley, A.; Amirthalingam, G.; Brown, K.; Ramsay, M. E.; Ladhani, S.; Moss, P.
10.1101/2020.11.01.362319 — immunology — Posted on 2020-11-02
3946 Beyond linearity in neuroimaging: Capturing nonlinear relationships with application to longitudinal studies
Chen, G.; Nash, T. A.; Reding, K. M.; Kohn, P. D.; Wei, S.-M.; Gregory, M. D.; Eisenberg, D. P.; Cox, R. W.; Berman, K. F.; Kippenhan, J. S.
10.1101/2020.11.01.363838 — neuroscience — Posted on 2020-11-02
3947 A molecular calcium integrator reveals a striatal cell-type driving aversion
Kim, C. K.; Sanchez, M. I.; Hoerbelt, P.; Fenno, L. E.; Malenka, R. C.; Deisseroth, K.; Ting, A. Y.
10.1101/2020.11.01.364174 — neuroscience — Posted on 2020-11-02
3949 Functional brain network topology across the menstrual cycle is sex hormone dependent and correlates with the individual well-being
Liparoti, M.; Troisi Lopez, E.; Sarno, L.; Rucco, R.; Minino, R.; Pesoli, M.; Perruolo, G.; Formisano, P.; Lucidi, F.; Sorrentino, G.; Sorrentino, P.
10.1101/2020.11.01.363937 — neuroscience — Posted on 2020-11-02
3950 Synaptotagmin-7 places dense-core vesicles at the cell membrane to promote Munc13-2- and Ca2+-dependent priming
Tawfik, B.; Martins, J. S.; Houy, S.; Imig, C.; Pinheiro, P. S.; Wojcik, S. M.; Brose, N.; Cooper, B. H.; Sorensen, J. B.
10.1101/2020.11.02.365478 — neuroscience — Posted on 2020-11-02
3953 Bacterially produced small molecules stimulate diatom growth
Sittmann, J.; Bae, M.; Mevers, E.; Li, M.; Quinn, A.; Sriram, G.; Clardy, J.; Liu, Z.
10.1101/2020.11.02.365239 — plant biology — Posted on 2020-11-02
3954 Canopy micrometeorology monitoring in diverse climates innovatively improves the evaluation heat-induced sterility of rice under climate change
Yoshimoto, M.; Fukuoka, M.; Tsujimoto, Y.; Matsui, T.; Kobayasi, K.; Saito, K.; van Oort, P. A. J.; Inusah, B. I. Y.; Vijayalakshmi, C.; Vijayalakshmi, D.; Weerakoon, W. M. W.; Chandradasa, S.; Myint Daw, T. T.; Phyo Daw, Z. C.; Tian, X.; Lur, H.-S.; Yang, C.-M.; Tarpley, L.; Manigbas, N. L.; Hasegawa, T.
10.1101/2020.11.01.363143 — plant biology — Posted on 2020-11-02
3955 Rare instances of haploid inducer DNA in potato dihaploids and ploidy-dependent genome instability
Amundson, K. R.; Ordonez, B.; Santayana, M.; Nganga, M. L.; Henry, I. M.; Bonierbale, M.; Khan, A.; Tan, E. H.; Comai, L.
10.1101/2020.11.02.365601 — plant biology — Posted on 2020-11-02
3960 SATB2 induction of a neural crest mesenchyme-like program drives invasion and drug resistance in melanoma
Fazio, M.; van Rooijen, E.; Dang, M.; van de Hoek, G.; Ablain, J.; Mito, J. K.; Yang, S.; Thomas, A.; Michael, J.; Fabo, T.; Modhurima, R.; Pessina, P.; Kaufman, C. K.; Zhou, Y.; White, R. M.; Zon, L. I.
10.1101/2020.11.01.364406 — cancer biology — Posted on 2020-11-02
3964 OmicPioneer-sc: an integrated, interactive visualization environment for single-cell sequencing data
Weinstein, J. N.; Rohrdanz, M. N.; Stucky, M. T.; Melott, J. M.; Jun, M.; Mohanty, V.; Manyam, G. C.; Wakefield, C.; Chen, K.; Navin, N.; Ryan, M. C.; Akbani, R.; Broom, B. M.
10.1101/2020.10.31.363580 — bioinformatics — Posted on 2020-11-02
3966 Genetic diversity analysis of the D614G mutation in SARS-CoV-2
Felix, P. T.; Silva, E. D. A. B.; Venancio, D. B. R.; Ramos, R. d. S.
10.1101/2020.10.30.362954 — bioinformatics — Posted on 2020-11-02
3968 Temporal patterns in the evolutionary genetic distance of SARS-CoV-2 during the COVID-19 pandemic
Lou, J.; Zhao, S.; Cao, L.; Chen, Z.; Chan, R. W.; Chong, M. K.; Zee, B. C.; Chan, P. K.; Wang, M. H.
10.1101/2020.11.01.363739 — bioinformatics — Posted on 2020-11-02
3970 MetaPop: A pipeline for macro- and micro-diversity analyses and visualization of microbial and viral metagenome-derived populations
Gregory, A. C.; Gerhardt, K.; Zhong, Z.-P.; Bolduc, B.; Temperton, B.; Konstantinidis, K. T. C.; Sullivan, M. B.
10.1101/2020.11.01.363960 — bioinformatics — Posted on 2020-11-02
3974 In vivo optical metabolic imaging of long-chain fatty acid uptake in orthotopic models of triple negative breast cancer
Madonna, M. C.; Duer, J. E.; Lee, J. V.; Williams, J.; Avsaroglu, B.; Zhu, C.; Deutsch, R.; Wang, R.; Crouch, B.; Hirschey, M.; Goga, A.; Ramanujam, N.
10.1101/2020.11.02.365288 — bioengineering — Posted on 2020-11-02
3975 Bioassemblying Macro-Scale, Lumnized Airway Tubes of Defined Shape via Multi-Organoid Patterning and Fusion
Liu, Y.; Dabrowska, C.; Mavousian, A.; Strauss, B.; Meng, F.; Mazzaglia, C.; Ouaras, K.; Macintosh, C.; Terentjev, E. M.; Lee, J.-H.; Huang, Y. Y. S.
10.1101/2020.11.01.363705 — bioengineering — Posted on 2020-11-02
3976 Senotherapeutic peptide reduces skin biological age and improves skin health
Zonari, A.; Brace, L. E.; Alkatib, K.; Porto, W. F.; Foyt, D.; Guiang, M.; Cruz, E. A. O.; Marshall, B.; Salgueiro, W. G.; Inan, M. D.; Rahman, M.; Anupom, T.; Vanapalli, S.; Mori, M. A.; Franco, O. L.; Oliveira, C. R.; Boroni, M.; Carvalho, J. L.
10.1101/2020.10.30.362822 — bioengineering — Posted on 2020-11-02
3978 Climate warming weakens local adaptation
Bontrager, M.; Muir, C. D.; Mahony, C. R.; Gamble, D. E.; Germain, R. M.; Hargreaves, A. L.; Kleynhans, E. J.; Thompson, K. A.; Angert, A. L.
10.1101/2020.11.01.364349 — evolutionary biology — Posted on 2020-11-02
3980 Mosquitoes of the Maculipennis complex in Northern Italy
Calzolari, M.; Desiato, R.; Albieri, A.; Bellavia, V.; Bertola, M.; Bonilauri, P.; Callegari, E.; Canziani, S.; Lelli, D.; Mosca, A.; Mulatti, P.; Peletto, S.; Ravagnan, S.; Roberto, P.; Torri, D.; Pombi, M.; Di Luca, M.; Montarsi, F.
10.1101/2020.11.02.365262 — ecology — Posted on 2020-11-02
3982 Photocatalyst under visible light irradiation inactivates SARS-CoV-2 on an abiotic surface
Uema, M.; Yonemitsu, K.; Momose, Y.; Ishii, Y.; Tateda, K.; Inoue, T.; Asakura, H.
10.1101/2020.11.01.364364 — microbiology — Posted on 2020-11-02
3983 Rapid inactivation of SARS-CoV-2 with ozone water
Inagaki, H.; Saito, A.; Sudaryatma, P. E.; Sugiyama, H.; Okabayashi, T.; Fujimoto, S.
10.1101/2020.11.01.361766 — microbiology — Posted on 2020-11-02
3984 The effect of heat on SARS-CoV-2 viability and RNA integrity as determined by plaque assay, virus culture and real-time RT-PCR
Burton, J. E.; Love, H.; Richards, K.; Burton, C.; Summers, S.; Pitman, J.; Easterbrook, L.; Davies, K.; Spencer, P.; Killip, M. J.; Cane, P. A.; Bruce, C. B.; Roberts, A. D. G.
10.1101/2020.11.02.365015 — microbiology — Posted on 2020-11-02
3985 The SARS-CoV-2 RNA interactome
Lee, S.; Lee, Y.-s.; Choi, Y.; Son, A.; Park, Y.; Lee, K.-M.; Kim, J.; Kim, J.-S.; Kim, V. N.
10.1101/2020.11.02.364497 — microbiology — Posted on 2020-11-02
3986 Chemical signatures of human odour generate a unique neural code in the brain of Aedes aegypti mosquitoes
Zhao, Z.; Zung, J. L.; Kriete, A. L.; Iqbal, A.; Younger, M. A.; Matthews, B. J.; Merhof, D.; Thiberge, S.; Strauch, M.; McBride, C. S.
10.1101/2020.11.01.363861 — neuroscience — Posted on 2020-11-02
3987 Intact sensory processing but hampered conflict detection when stimulus input is task-irrelevant
Nuiten, S. A.; Canales-Johnson, A.; Beerendonk, L.; Nanuashvili, N.; Fahrenfort, J. J.; Bekinschtein, T.; van Gaal, S.
10.1101/2020.10.31.363192 — neuroscience — Posted on 2020-11-02
3988 Effects of external stimulation on psychedelic state neurodynamics
Mediano, P. A. M.; Rosas, F. E.; Timmermann, C.; Roseman, L.; Nutt, D. J.; Feilding, A.; Kaelen, M.; Kringelbach, M. L.; Barrett, A. B.; Seth, A. K.; Muthukumaraswamy, S.; Bor, D.; Carhart-Harris, R. L.
10.1101/2020.11.01.356071 — neuroscience — Posted on 2020-11-02
3990 Structural basis for repurpose and design of nucleoside drugs for treating COVID-19
Yin, W.; Luan, X.; Li, Z.; Xie, Y.; Zhou, Z.; Liu, J.; Gao, M.; Wang, X.; Zhou, F.; Wang, Q.; Wang, Q.; Shen, D.; Zhang, Y.; Tian, G.; Aisa, H. A.; Hu, T.; Wei, D.; Jiang, Y.; Xiao, G.; Jiang, H.; Zhang, L.; Yu, X.; Shen, J.; Zhang, S.; Xu, H. E.
10.1101/2020.11.01.363812 — biophysics — Posted on 2020-11-02
3997 SARS-CoV-2 induces double-stranded RNA-mediated innate immune responses in respiratory epithelial derived cells and cardiomyocytes
Li, Y.; Renner, D.; Comar, C. E.; Whelan, J.; Reyes, H.; Cardenas-Diaz, F. L.; Truitt, R.; Tan, L. H.; Dong, B.; Alysandratose, K. D.; Huang, J.; Palmer, J. N.; Adappa, N. D.; Kohanski, M. A.; Kotton, D. N.; Silverman, R. H.; Yang, W.; Morrisey, E.; Cohen, N.; Weiss, S. R.
10.1101/2020.09.24.312553 — microbiology — Posted on 2020-11-02
3999 Ethacridine inhibits SARS-CoV-2 by inactivating viral particles in cellular models
Li, X.; Lidsky, P.; Xiao, Y.; Wu, C.-T.; Garcia-Knight, M.; Yang, J.; Nakayama, T.; Nayak, J. V.; Jackson, P. K.; Andino, R.; Shu, X.
10.1101/2020.10.28.359042 — microbiology — Posted on 2020-11-02
4001 The COVID-19 immune landscape is dynamically and reversibly correlated with disease severity
Bolouri, H.; Speake, C.; Skibinski, D.; Long, S. A.; Hocking, A. M.; Campbell, D. J.; Hamerman, J. A.; Malhotra, U.; Buckner, J. H.; BRI COVID-19 Research Team,
10.1101/2020.09.18.303420 — immunology — Posted on 2020-11-02
4002 Focus-tunable microscope for imaging small neuronal processes in freely moving animals
Bagramyan, A.; Tabourin, L.; Rastqar, A.; Karimi, N.; Bretzner, F.; Galstian, T.
10.1101/2020.10.31.363507 — neuroscience — Posted on 2020-11-02
4003 Differential alteration of plant functions by homologous fungal candidate effectors
Goncalves dos Santos, K. C.; Pelletier, G.; Seguin, A.; Guillemette, F.; Hawkes, J.; Desgagne-Penix, I.; Germain, H.
10.1101/2020.10.30.363010 — plant biology — Posted on 2020-11-02
4004 Mutagenesis and homology modeling reveal a predicted pocket of lysophosphatidylcholine acyltransferase 2 to catch Acyl-CoA.
Hamano, F.; Matoba, K.; Hashidate, T.; Suzuki, T.; Miura, K.; Hishikawa, D.; Harayama, T.; Yuki, K.; Kita, Y.; Noda, N. N.; Shimizu, T.; Shindou, H.
10.1101/2020.10.31.363515 — biochemistry — Posted on 2020-11-02
4006 Molecular basis of F-actin regulation and sarcomere assembly via myotilin
Kostan, J.; Pavsic, M.; Puz, V.; Schwarz, T. C.; Drepper, F.; Molt, S.; Graewert, M. A.; Schreiner, C.; Sajko, S.; van der Ven, P. F. M.; Svergun, D.; Warscheid, B.; Konrat, R.; Fuerst, D. O.; Lenarcic, B.; Djinovic-Carugo, K.
10.1101/2020.09.25.310029 — biochemistry — Posted on 2020-11-02
4008 CoDNaS-RNA: a database of Conformational Diversity in the Native State of RNA
Gonzalez Buitron, M.; Tunque Cahui, R. R.; Garcia Rios, E.; Hirsh, L.; Fornasari, M. S.; Parisi, G.; Palopoli, N.
10.1101/2020.10.30.362590 — bioinformatics — Posted on 2020-11-02
4013 Single-dimensional human brain signals for two-dimensional economic choice options
Chi U Seak, L.; Volkmann, K.; Pastor-Bernier, A.; Grabenhorst, F.; Schultz, W.
10.1101/2020.04.06.028001 — neuroscience — Posted on 2020-11-02
4017 Induced pulmonary comorbidities render CD-1 mice sensitive to SARS-CoV-2
Falach, R.; Bar-On, L.; Lazar, S.; Kadar, T.; Mazor, O.; Aftalion, M.; Gur, D.; Shifman, O.; Israeli, O.; Cohen-Gihon, I.; Zaide, G.; Gutman, H.; Evgy, Y.; Vagima, Y.; Makdasi, E.; Stein, D.; Rosenfeld, R.; Alcalay, R.; Zahavy, E.; Levy, H.; Glinert, I.; Ben-Shmuel, A.; Israely, T.; Melamed, S.; Politi, B.; Achdout, H.; Yitzhaky, S.; Kronman, C.; Sabo, T.
10.1101/2020.10.28.358614 — pathology — Posted on 2020-11-02
4018 Priority effects alter interaction outcomes in a legume-rhizobium mutualism
Boyle, J. A.; Simonsen, A. K.; Frederickson, M. E.; Stinchcombe, J. R.
10.1101/2020.10.31.363267 — ecology — Posted on 2020-11-02
4019 A sparse observation model to quantify species interactions in time and space
Ait Kaci Azzou, S.; Singer, L.; Aebischer, T.; Caduff, M.; Wolf, B.; Wegmann, D.
10.1101/815027 — ecology — Posted on 2020-11-02
4020 Tracking H3K27me3 and H4K20me1 during XCI reveals similarities in enrichment dynamics
Tjalsma, S. J. D.; Hori, M.; Sato, Y.; Bousard, A.; Ohi, A.; Raposo, A. C.; Roensch, J.; Le Saux, A.; Nogami, J.; Maehara, K.; Kujirai, T.; Handa, T.; Bages-Arnal, S.; Ohkawa, Y.; Kurumizaka, H.; da Rocha, S. T.; Zylicz, J. J.; Kimura, H.; Heard, E.
10.1101/2020.08.06.228346 — developmental biology — Posted on 2020-11-02
4021 Transfer of Antibiotic Resistance Genes from Gram-positive Bacterium to Gram-negative Bacterium
Manohar, P.; Shanthini, T.; Bozdogan, B.; Lundborg, C. S.; Tamhankar, A. J.; Palaniyar, N.; Ramesh, N.
10.1101/2020.11.01.364331 — microbiology — Posted on 2020-11-02
4025 Orai1- and Orai2-, but not Orai3-mediated ICRAC is regulated by intracellular pH
Rychkov, G.; Zhou, F. H.; Adams, M. K.; Brierley, S. M.; Ma, L.; Barritt, G. J.
10.1101/2020.11.01.364299 — physiology — Posted on 2020-11-02
4027 Development of a Novel Index to Characterise Arterial Dynamics Using Ultrasound Imaging
Ward, J.; Cheng, X.; Xiao, Y.; Lapolla, P.; Chandrashekar, A.; Handa, A.; Cleveland, R.; Lee, R.
10.1101/2020.10.31.363291 — bioengineering — Posted on 2020-11-02
4028 TAD cliques predict key features of chromatin organization
Liyakat Ali, T. M.; Brunet, A.; Collas, P.; Paulsen, J.
10.1101/2020.11.01.363903 — genomics — Posted on 2020-11-02
4031 Microvilli-derived Extracellular Vesicles Govern Morphogenesis in Drosophila wing epithelium
Hurbain, I.; Mace, A.-S.; Romao, M.; Sengmanivong, L.; Ruel, L.; Basto, R.; Therond, P. P.; Raposo, G.; D'Angelo, G.
10.1101/2020.11.01.363697 — cell biology — Posted on 2020-11-02
4032 Sclerostin depletion induces inflammation in the bone marrow of mice
Donham, C.; Chicana, B.; Robling, A. G.; Mohamed, A.; Elizaldi, S.; Chi, M.; Freeman, B.; Millan, A.; Murguesh, D.; Loots, G. G.; Manilay, J. O.
10.1101/2020.11.01.364158 — immunology — Posted on 2020-11-02
4035 Measuring kinetics and metastatic propensity of CTCs by blood exchange between mice
Hamza, B.; Miller, A. B.; Meier, L.; Stockslager, M.; King, E. M.; Ng, S. R.; DeGouveia, K. L.; Mulugeta, N.; Calistri, N. L.; Strouf, H.; Lin, L.; Chin, C. R.; Weinberg, R.; Shalek, A. K.; Jacks, T.; Manalis, S.
10.1101/2020.11.01.350918 — cancer biology — Posted on 2020-11-01
4036 Investigating the causal effect of maternal vitamin B12 and folate levels on offspring birthweight
Moen, G.-H.; Beaumont, R. N.; Sommer, C.; Shields, B. M.; Lawlor, D. A.; Freathy, R. M.; Evans, D. M.; Warrington, N. M.
10.1101/2020.01.21.914655 — genetics — Posted on 2020-11-01
4037 Remote control of neural function by X-ray-induced scintillation
Matsubara, T.; Yanagida, T.; Kawaguchi, N.; Nakano, T.; Yoshimoto, J.; Sezaki, M.; Takizawa, H.; Tsunoda, S. P.; Horigane, S.-i.; Ueda, S.; Takemoto-Kimura, S.; Kandori, H.; Yamanaka, A.; Yamashita, T.
10.1101/798702 — neuroscience — Posted on 2020-11-01
4039 Uncovering the mesendoderm gene regulatory network through multi-omic data integration
Jansen, C.; Paraiso, K.; Zhou, J.; Blitz, I. L.; Fish, M.; Charney, R.; Cho, J. S.; Yasuoka, Y.; Sudou, N.; Bright, A. R.; Wlizla, M.; Veenstra, G. J. C.; Taira, M.; Zorn, A.; Mortazavi, A.; Cho, K. W. Y.
10.1101/2020.11.01.362053 — genomics — Posted on 2020-11-01
4042 An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients
The NeuroLINCS Consortium, ; Ornelas, L.; Gomez, E.; Panther, L.; Frank, A.; Lei, S.; Mandefro, B.; Banuelos, M. G.; Shelley, B.; Kaye, J. A.; Lima, L.; Wyman, S.; Lim, R. G.; Wu, J.; Stocksdale, J.; Casale, M.; Dardov, V.; Matlock, A.; Venkatraman, V.; Holewenski, R.; Milani, P.; Adam, M.; Wassie, B. T.; Cheng, A.; Coyne, A. N.; Daigle, J. G.; Li, J.; Yang, S.; Cox, V.; Wilhelm, M.; Lloyd, T. E.; Hayes, L.; Pham, J.; Escalante-Chong, R.; Lenail, A.; Sachs, K.; Patel-Murray, N. L.; Ramamoorthy, D.; Thompson, T. G.; NYGC ALS Consortium, ; Finkbeiner, S.; Fraenkel, E.; Rothstein, J. D.; Sareen
10.1101/2020.11.01.362269 — neuroscience — Posted on 2020-11-01
4043 Intestinal ferritinophagy is regulated by HIF-2 and is essential for systemic iron homeostasis
Das, N. K.; Sankar, A.; Schwartz, A. J.; Solanki, S.; Ma, X.; Parimi, S.; Santana-Codina, N.; Mancias, J. D.; Shah, Y. M.
10.1101/2020.11.01.364059 — physiology — Posted on 2020-11-01
4050 MondoA Drives Malignancy in cALL through Enhanced Adaptation to Metabolic Stress
Sipol, A.; Hameister, E.; Xue, B.; Petry, A.; Prexler, C.; Barenboim, M.; Rubio, R. A.; Baldauf, M. C.; Franchina, D. G.; Schmaeh, J.; Richter, G.; Cario, G.; Gruenewald, T. G. P.; Goerlach, A.; Brenner, D.; Ruland, J.; Sorensen, P. H.; Burdach, S. E. G.
10.1101/2020.11.01.363986 — cancer biology — Posted on 2020-11-01
4051 Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway
Cason, S. E.; Carman, P. J.; Van Duyne, C.; Goldsmith, J.; Dominguez, R.; Holzbaur, E. L. F.
10.1101/2020.11.01.363333 — cell biology — Posted on 2020-11-01
4052 CRISPR-Cas13 mediated Knock Down in Drosophila cultured cells.
Viswanatha, R.; Zaffagni, M.; Zirin, J.; Perrimon, N.; Kadener, S.
10.1101/2020.11.01.364166 — molecular biology — Posted on 2020-11-01
4055 Differential response of macrophages and neutrophils to trypanosome infections in zebrafish: occurrence of foamy macrophages
Jacobs, S. H.; Doro, E.; Hammond, F. R.; Nguyen-Chi, M. E.; Lutfalla, G.; Wiegertjes, G. F.; Forlenza, M.
10.1101/2020.11.01.363721 — microbiology — Posted on 2020-11-01
4056 Genetic diversity of blaKPC-gene-containing IncF plasmids from epidemiologically related and unrelated Enterobacteriaceae
Stohr, J. J. J. M.; Kluytmans-van den Bergh, M. F. Q.; Weterings, V. A. T. C.; Rossen, J. W. A.; Kluytmans, J. A. J. W.
10.1101/2020.11.01.362400 — microbiology — Posted on 2020-11-01
4063 The mammalian CLU homolog FMT controls development and behavior in Arabidopsis
Horvath, T.; Ralevski, A.; Apelt, F.; Olas, J.; Mueller-Roeber, B.; Rugarli, E.; Kragler, F.
10.1101/2020.08.01.231183 — plant biology — Posted on 2020-11-01
4065 A biophysical and structural analysis of DNA binding by oligomeric hSSB1 (NABP2/OBFC2B)
El-Kamand, S.; Jergic, S.; Lawson, T.; Kariawasam, R.; Richard, D. J.; Cubeddu, L.; Gamsjaeger, R.
10.1101/2020.08.26.269084 — biochemistry — Posted on 2020-11-01
4066 Evaluation of the antiviral effect of chlorine dioxide (ClO2) using a vertebrate model inoculated with avian coronavirus
Zambrano-Estrada, X.; Dominguez-Sanchez, C. A.; Banuet-Martinez, M.; Guerrero-de la Rosa, F.; Garcia-Gasca, T.; Prieto-Valiente, L.; Acevedo-Whitehouse, K.
10.1101/2020.10.13.336768 — microbiology — Posted on 2020-11-01
4070 Tetravalent SARS-CoV-2 Neutralizing Antibodies Show Enhanced Potency and Resistance to Escape Mutations
Miersch, S.; Li, Z.; Saberianfar, R.; Ustav, M.; Blazer, L.; Chen, C.; Ye, W.; Pavlenco, A.; Subramnia, S.; Singh, S.; Ploder, L.; Ganaie, S.; Leung, D.; Case, J. B.; Novelli, G.; Matusali, G.; Chen, R.; Colavita, F.; Copabianchi, M. R.; Jain, S.; Gupta, J. B.; Amarasinghe, G.; Diamond, M. S.; Rini, J.; Sidhu, S.
10.1101/2020.10.31.362848 — synthetic biology — Posted on 2020-11-01
4075 A Connectome-Based Approach to Assess Motor Outcome after Neonatal Arterial Ischemic Stroke
Al Harrach, M.; Pretzel, P.; Groeschel, S.; Dhollander, T.; Hertz-Pannier, L.; Lefevre, J.; Chabrier, S.; Dinomais, M.
10.1101/2020.08.24.265173 — bioengineering — Posted on 2020-11-01
4080 Highly-parallel microfluidics-based force spectroscopy on single cytoskeletal motors
Urbanska, M.; Lüdecke, A.; Walter, W. J.; van Oijen, A. M.; Duderstadt, K. E.; Diez, S.
10.1101/2020.08.11.245910 — biophysics — Posted on 2020-11-01
4081 Advanced Whole Genome Sequencing Using an Entirely PCR-free Massively Parallel Sequencing Workflow
Xia, Z.; Jiang, Y.; Drmanac, R.; Shen, H.; Liu, P.; Li, Z.; Chen, F.; Jiang, H.; Shi, S.; Xi, Y.; Li, Q.; Wang, X.; Zhao, J.; Liang, X.; Xie, Y.; Wang, L.; Tian, W.; Berntsen, T.; Luo, Y.; Gong, M.; Li, J.; Xu, C.; Dai, S.; Mi, Z.; Ren, H.; Lin, Z.; Chen, A.; Zhang, W.; Mu, F.; Xu, X.
10.1101/2019.12.20.885517 — genomics — Posted on 2020-11-01
4084 Comparative transcriptomic analysis reveals conserved transcriptional programs underpinning organogenesis and reproduction in land plants
Julca, I.; Flores, M.; Proost, S.; Lindner, A.-C.; Hackenberg, D.; Steinbachova, L.; Michaelidis, C.; Gomes Pereira, S.; Misra, C. S.; Kawashima, T.; Borg, M.; Berger, F.; Goldberg, J.; Johnson, M.; Honys, D.; Twell, D.; Sprunck, S.; Dresselhaus, T.; Becker, J.; Mutwil, M.
10.1101/2020.10.29.361501 — evolutionary biology — Posted on 2020-11-01
4087 Beauty and the brain: Investigating the neural and musical attributes of beauty during a naturalistic music listening experience
Brattico, E.; Brusa, A.; Dietz, M. J.; Jacobsen, T.; Fernandes, H.; Gaggero, G.; Toiviainen, P.; Vuust, P.; Proverbio, A. M.
10.1101/2020.10.31.363283 — neuroscience — Posted on 2020-11-01
4089 Genome ARTIST_v2 software - a support for annotation of class II natural transposons in new sequenced genomes
Ecovoiu, A. A.; Ghita, I. C.; Chifiriuc, D. I. M.; Ghionoiu, I. C.; Ciuca, A. M.; Bologa, A. M.; Ratiu, A. C.
10.1101/2020.10.30.360610 — bioinformatics — Posted on 2020-11-01
4091 An efficient and accurate frailty model approach for genome-wide survival association analysis controlling for population structure and relatedness in large-scale biobanks
Dey, R.; Zhou, W.; Kiiskinen, T.; Havulinna, A.; Elliott, A.; Karjalainen, J.; Kurki, M.; Qin, A.; FinnGen, ; Lee, S.; Palotie, A.; Neale, B. M.; Daly, M. J.; Lin, X.
10.1101/2020.10.31.358234 — genomics — Posted on 2020-11-01
4092 Infant Inhibited Temperament in Primates Predicts Adult Behavior, is Heritable, and is Associated with Anxiety Relevant Genetic Variation
Fox, A. S.; Harris, R. A.; Del Rosso, L.; Raveendran, M.; Kamboj, S.; Kinnally, E. L.; Capitanio, J. P.; Rogers, J.
10.1101/2020.10.30.361477 — genetics — Posted on 2020-11-01
4093 MINSTED fluorescence localization and nanoscopy
Weber, M.; Leutenegger, M.; Stoldt, S.; Jakobs, S.; Mihaila, T. S.; Butkevich, A. N.; Hell, S. W.
10.1101/2020.10.31.363424 — biophysics — Posted on 2020-11-01
4095 Climate influences the response of community functional traits to local conditions
Guzman, L. M.; Trzcinski, M. K.; Barberis, I. M.; Cereghino, R.; Srivastava, D. S.; Gilbert, B.; Pillar, V.; De Omena, P.; MacDonald, A. A. M.; Corbara, B.; Leroy, C.; Ospina Bautista, F.; Romero, G. Q.; Katrina, P.; Debastiani, V. J.; Goncalves, A. Z.; Marino, N. A. C.; Farjalla, V.; Richardson, B.; Richardson, M. J.; Dezerald, O.; Piccoli, G. C. O.; Jocque, M.; Montero, G.
10.1101/2020.10.30.362525 — ecology — Posted on 2020-11-01
4100 Photosynthetic activity triggers pH and NAD redox signatures across different plant cell compartments
Elsässer, M.; Feitosa-Araujo, E.; Lichtenauer, S.; Wagner, S.; Fuchs, P.; Giese, J.; Kotnik, F.; Hippler, M.; Meyer, A.; Maurino, V. G.; Finkemeier, I.; Schallenberg-Rüdinger, M.; Schwarzländer, M.
10.1101/2020.10.31.363051 — plant biology — Posted on 2020-11-01
4107 Paper-based Sensing of Fucosylated Biological Compounds
Enam, F.; Mansell, T. J.; Kramer, E.; Robinson, F.; Alvarez-Acosta, A.; Cademartiri, R.
10.1101/2020.10.30.362889 — biochemistry — Posted on 2020-11-01
4112 Occurrence but not intensity of mortality rises towards the climatic trailing edge of tree species ranges in European forests.
Changenet, A.; Ruiz-Benito, P.; Ratcliffe, S.; Frejaville, T.; Archambeau, J.; Porte, A. J.; Zavala, M. A.; Dahlgren, J.; Lehtonen, A.; Benito Garzon, M.
10.1101/2020.10.30.362087 — ecology — Posted on 2020-11-01
4114 Hippocampus shape across the healthy lifespan and its relationship with cognition
Bussy, A.; Patel, R.; Plitman, E.; Tullo, S.; Salaciak, A.; Bedford, S.; Farzin, S.; Beland, M.-L.; Valiquette, V.; Kazazian, C.; Tardif, C.; Devenyi, G.; Chakravarty, M.
10.1101/2020.10.30.362921 — neuroscience — Posted on 2020-11-01
4118 Evaluation of azithromycin or hydroxychloroquine plus azithromycin combination therapy on cardiac conduction and function in guinea pigs
Li, X.; Tan, W.; Zheng, S.; Sun, H.; Zhang, X.; Li, X.; Chen, H.; Ren, X.; He, T.; Zhu, C.; Zhang, Y.; Yang, F. H.
10.1101/2020.10.31.362566 — physiology — Posted on 2020-11-01
4120 Ethnicity-specific transcriptomic variation in immune cells and correlation with disease activity in systemic lupus erythematosus
Andreoletti, G.; Lanata, C. M.; Paranjpe, I.; Jain, T. S.; Nititham, J.; Taylor, K. E.; Combes, A. J.; Maliskova, L.; Jimmie Ye, C.; Katz, P.; Dall Era, M.; Yazdany, J.; Criswell, L. A.; Sirota, M.
10.1101/2020.10.30.362715 — bioinformatics — Posted on 2020-11-01
4122 Redefining the specificity of phosphoinositide-binding by human PH domain-containing proteins
Singh, N.; Reyes-Ordonez, A.; Compagnone, M. A.; Moreno Castillo, J. F.; Leslie, B. J.; Ha, T.; Chen, J.
10.1101/2020.06.20.163253 — biochemistry — Posted on 2020-11-01
4123 Structural Basis of Stu2 Recruitment to Yeast Kinetochores
Zahm, J. A.; Stewart, M. G.; Carrier, J. S.; Harrison, S. C.; Miller, M. P.
10.1101/2020.10.31.362574 — biochemistry — Posted on 2020-11-01
4127 CryoET structures of immature HIV Gag reveal a complete six-helix bundle and stabilizing small molecules distinct from IP6
Mendonca, L.; Sun, D.; Ning, J.; Liu, J.; Kotecha, A.; Olek, M.; Frosio, T.; Fu, X.; Himes, B. A.; Kleinpeter, A. B.; Freed, E. O.; Zhou, J.; Aiken, C.; Zhang, P.
10.1101/2020.10.31.363382 — microbiology — Posted on 2020-11-01