bioRxiv directory

1 Implantation-Competent Blastocyst-Like Structures from Mouse Pluripotent Stem Cells

Kime, C.; Kiyonari, H.; Ohtsuka, S.; Kohbayashi, E.; Asahi, M.; Yamanaka, S.; Takahashi, M.; Tomoda, K.

10.1101/309542 — developmental biology — Posted on 2018-04-30

2 Drosophila mef2 is essential for normal mushroom body and wing development.

Crittenden, J. R.; Skoulakis, E. M.; Goldstein, E. S.; Davis, R. L.

10.1101/311845 — developmental biology — Posted on 2018-04-30

3 Clear, extended field-of-view single-molecule imaging by highly inclined swept illumination

Tang, J.; Han, K. Y.

10.1101/311753 — biophysics — Posted on 2018-04-30

4 eNetXplorer: an R package for the quantitative exploration of elastic net families for generalized linear models

Candia, J.; Tsang, J. S.

10.1101/305870 — systems biology — Posted on 2018-04-30

5 A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection

Fourati, S.; Talla, A.; Mahmoudian, M.; Burkhart, J. G.; Klen, R.; Henao, R.; Aydin, Z.; Yeung, K. Y.; Ahsen, M. E.; Almugbel, R.; Jahandideh, S.; Liang, X.; Nordling, T. E. M.; Shiga, M.; Stanescu, A.; Vogel, R.; The Respiratory Viral DREAM Challenge Consortium, ; Pandey, G.; Chiu, C.; McClain, M. T.; Woods, C. W.; Ginsburg, G. S.; Elo, L. L.; Tsalik, E. L.; Mangravite, L. M.; Sieberts, S. K.

10.1101/311696 — immunology — Posted on 2018-04-30

6 FORGe: prioritizing variants for graph genomes

Pritt, J.; Langmead, B.

10.1101/311720 — bioinformatics — Posted on 2018-04-30

7 Neonatal gut-microbiome-derived 12,13 DiHOME impedes tolerance and promotes childhood atopy and asthma

Levan, S. R.; Stamnes, K. A.; Lin, D. L.; Fujimura, K. E.; Ownby, D. R.; Zoratti, E. M.; Boushey, H. A.; Johnson, C. C.; Lynch, S. V.

10.1101/311704 — microbiology — Posted on 2018-04-30

8 Changes in the gut microbiota and fermentation products associated with enhanced longevity in acarbose-treated mice

Smith, B. J.; Miller, R. A.; Ericsson, A. C.; Harrison, D. E.; Strong, R.; Schmidt, T. M.

10.1101/311456 — microbiology — Posted on 2018-04-30

9 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

Dekker, J. D.; Rhee, C.; Hu, Z.; Lee, B.-K.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Tucker, H. O.; Ippolito, G. C.

10.1101/310680 — immunology — Posted on 2018-04-30

10 Chromatin features constrain structural variation across evolutionary timescales

Fudenberg, G.; Pollard, K.

10.1101/285205 — genomics — Posted on 2018-04-30

11 Transposable elements generate regulatory novelty in a tissue-specific fashion

Trizzino, M.; Kapusta, A.; Brown, C.

10.1101/268771 — genomics — Posted on 2018-04-30

12 Genome-wide Association Study for Noise-induced Cochlear Synaptopathy.

Lavinsky, J.; Dermanaki, P. S.; Wang, J.; Friedman, R. A.

10.1101/311407 — genetics — Posted on 2018-04-30

13 Genetic Determinants of Telomere Length in African American Youth

Zeiger, A. M.; White, M. J.; Oh, S. S.; Witonsky, J.; Contreras, M. G.; Goddard, P. C.; Lee, E. Y.; Keys, K. L.; Samedy, L.-A.; Liberto, J. R.; Mak, A. C. Y.; Magana, J.; Risse-Adams, O.; Eng, C.; Hu, D.; Huntsman, S.; Salazar, S.; Davis, A.; Meade, K.; Brigino-Buenaventura, E.; LeNoir, M. A.; Farber, H. J.; Bibbins-Domingo, K.; Borrell, L. N.; Burchard, E. G.

10.1101/310417 — genetics — Posted on 2018-04-30

14 Divergent Roles for cAMP-PKA Signaling in the Regulation of Filamentous Growth in Saccharomyces cerevisiae and Saccharomyces bayanus

Kayikci, O.; Magwene, P. M.

10.1101/311415 — evolutionary biology — Posted on 2018-04-30

15 The lost world of Cuatro Cienegas Basin, a relictual bacterial niche in a desert oasis.

Moreno-Letelier, A.; Souza, V.; Travisano, M.; Alcaraz, L. D.; Olmedo, G.; Eguiarte, L. E.

10.1101/311381 — evolutionary biology — Posted on 2018-04-30

16 MicroCOSM: a model of social and structural drivers of HIV and interventions to reduce HIV incidence in high-risk populations in South Africa

Johnson, L. F.; Kubjane, M.; Moolla, H.

10.1101/310763 — epidemiology — Posted on 2018-04-30

17 A cell separation checkpoint that enforces the proper order of late cytokinetic events

Brace, J. L.; Doerfler, M. D.; Weiss, E. L.

10.1101/308411 — cell biology — Posted on 2018-04-30

18 Temporally feathered intensity modulated radiation therapy: a planning technique to reduce normal tissue toxicity

Alfonso, J. C. L.; Parsai, S.; Joshi, N.; Godley, A.; Shah, C.; Koyfman, S. A.; Caudell, J. J.; Fuller, C. D.; Enderling, H.; Scott, J.

10.1101/184044 — biophysics — Posted on 2018-04-30

19 Automated Segmentation of Epithelial Tissue Using Cycle-Consistent Generative Adversarial Networks

Haering, M.; Grosshans, J.; Wolf, F.; Eule, S.

10.1101/311373 — bioinformatics — Posted on 2018-04-30

20 Spatial Attention Enhances the Neural Representation of Invisible Signals Embedded in Noise

Smout, C. A.; Mattingley, J. B.

10.1101/102731 — neuroscience — Posted on 2018-04-30

21 M1A within cytoplasmic mRNAs at single nucleotide resolution: A reconciled transcriptome-wide map

Schwartz, S.

10.1101/308437 — molecular biology — Posted on 2018-04-30

22 Genetic regulatory mechanisms of smooth muscle cells map to coronary artery disease risk loci

Liu, B.; Pjanic, M.; Wang, T.; Nguyen, T.; Gloudemans, M.; Rao, A.; Castano, V. G.; Nurnberg, S. T.; Rader, D. J.; Elwyn, S.; Ingelsson, E.; Montgomery, S. B.; Miller, C. L.; Quertermous, T.

10.1101/309559 — genomics — Posted on 2018-04-30

23 Genome-wide association study results for educational attainment aid in identifying genetic heterogeneity of schizophrenia

Bansal, V.; Mitjans, M.; Burik, C. A. P.; Karlsson Linner, R.; Okbay, A.; Rietveld, C. A.; Begemann, M.; Bonn, S.; Ripke, S.; Vlaming, R. d.; Nivard, M. G.; Ehrenreich, H.; Koellinger, P. D.

10.1101/114405 — genetics — Posted on 2018-04-30

24 Global immune fingerprinting in glioblastoma reveals immune-suppression signatures associated with prognosis

Alban, T. J.; Alvarado, A. G.; Sorensen, M. D.; Bayik, D.; Volovetz, J.; Serbinowski, E.; Mulkearns-Hubert, E.; Sinyuk, M.; Hale, J. S.; Onzi, G. R.; McGraw, M.; Huang, P.; Grabowski, M. M.; Wathen, C. A.; Radivoyevitch, T.; Kornblum, H. I.; Kristensen, B. W.; Vogelbaum, M. A.; Lathia, J. D.

10.1101/309807 — cancer biology — Posted on 2018-04-30

25 Calcium-Calmodulin Gating of Connexin43 Gap Junctions in the Absence of the pH Gating Domain

Veenstra, R. D.

10.1101/311613 — biophysics — Posted on 2018-04-30

26 Gating Mechanisms during Actin Filament Elongation by Formins

Aydin, F.; Courtemanche, N.; Pollard, T. D.; Voth, G. A.

10.1101/311431 — biophysics — Posted on 2018-04-30

27 A feeding aggregation of Omura‘s whale Balaenoptera omurai off Nosy Be, Mozambique Channel

Laboute, P.; Borsa, P.

10.1101/311043 — zoology — Posted on 2018-04-30

28 High impact journals in ecology cover proportionally more statistically significant findings

Ceausu, S.; Borda-de-Agua, L.; Merckx, T.; Sossai, E.; Sapage, M.; Miranda, M.; Pereira, H. M.

10.1101/311068 — scientific communication and education — Posted on 2018-04-30

29 Opposing pupil responses to offered and anticipated reward values

Cash-Padgett, T.; Azab, H.; Yoo, S. B. M.; Hayden, B. Y.

10.1101/298844 — neuroscience — Posted on 2018-04-30

30 ADAM22 and ADAM23 modulate the targeting of the Kv1 channel-associated protein LGI1 to the axon initial segment

Hivert, B.; Marien, L.; Agbam, K. N.; Faivre-Sarrailh, C.

10.1101/311365 — neuroscience — Posted on 2018-04-30

31 Longitudinal tracking of Plasmodium falciparum clones in complex infections by amplicon deep sequencing

Lerch, A.; Koepfli, C.; Hofmann, N. E.; Kattenberg, J. H.; Rosanas-Urgell, A.; Betuela, I.; Mueller, I.; Felger, I.

10.1101/306860 — microbiology — Posted on 2018-04-30

32 The landscape of pervasive horizontal pleiotropy in human genetic variation is driven by extreme polygenicity of human traits and diseases

Jordan, D. M.; Verbanck, M.; Do, R.

10.1101/311332 — genetics — Posted on 2018-04-30

33 Inter-annual variation in seasonal dengue epidemics driven bymultiple interacting factors in Guangzhou, China

Oidtman, R. J.; Lai, S.; Huang, Z.; Siraj, A. S.; Reiner, R. C.; Tatem, A. J.; Perkins, A.; Yu, H.

10.1101/310896 — epidemiology — Posted on 2018-04-30

34 Plantarflexor Moment Arms Estimated From Tendon Excursion In Vivo Are Not Well Correlated With Geometric Measurements

Baxter, J. R.; Piazza, S. J.

10.1101/290916 — bioengineering — Posted on 2018-04-30

35 A Double Error Dynamic Asymptote Model of Associative Learning

Kokkola, N. H. B.; Mondragon, E.; Alonso, E.

10.1101/210674 — animal behavior and cognition — Posted on 2018-04-30

36 Beyond the traditional simulation design for evaluating type 1 error rate: from ‘theoretical’ to ‘empirical’ null

Zhang, T.; Sun, L.

10.1101/311290 — scientific communication and education — Posted on 2018-04-30

37 Interneuronal gap junctions increase synchrony and robustness of hippocampal ripple oscillations

Holzbecher, A.; Kempter, R.

10.1101/311662 — neuroscience — Posted on 2018-04-30

38 Decision-making increases episodic memory via post-encoding consolidation.

Murty, V.; DuBrow, S.; Davachi, L.

10.1101/311571 — neuroscience — Posted on 2018-04-30

39 MIN1PIPE: A Miniscope 1-photon-based Calcium Imaging Signal Extraction Pipeline

Lu, J.; Li, C.; Singh-Alvarado, J.; Zhou, Z.; Fröhlich, F.; Mooney, R.; Wang, F.

10.1101/311548 — neuroscience — Posted on 2018-04-30

40 Small RNAs gained during epididymal transit of sperm are essential for embryonic development in mice

Conine, C.; Sun, F.; Song, L.; Rivera-Perez, J.; Rando, O.

10.1101/311670 — molecular biology — Posted on 2018-04-30

41 A systematic survey of human tissue-specific gene expression and splicing reveals new opportunities for therapeutic target identification and evaluation

Yang, R. Y.; Quan, J.; Sodaie, R.; Aguet, F.; Segre, A. V.; Allen, J. A.; Lanz, T. A.; Reinhart, V.; Crawford, M.; Hasson, S.; GTEx Consortium, ; Ardlie, K. G.; Guigo, R.; Xi, H. S.

10.1101/311563 — genomics — Posted on 2018-04-30

42 Convergent transcriptomic landscapes under polygenic selection accompany inter-continental parallel evolution within a Nearctic Coregonus (Salmonidae) sister-species complex.

Rougeux, C.; Gagnaire, P.-A.; Praebel, K.; Seehausen, O.; Bernatchez, L.

10.1101/311464 — evolutionary biology — Posted on 2018-04-30

43 The impact of a governmental cash transfer programme on tuberculosis cure rate in Brazil: A quasi-experimental approach

Carter, D. J.; Daniel, R.; Torrens, A. W.; Sanchez, M. N.; Maciel, E. L. N.; Bartholomay, P.; Barreira, D. C.; Rasella, D.; Barreto, M. L.; Rodrigues, L. C.; Boccia, D.

10.1101/311589 — epidemiology — Posted on 2018-04-30

44 Changes in the Biodiversity Intactness Index in tropical and subtropical forest biomes, 2001-2012.

De Palma, A.; Hoskins, A.; Gonzalez, R. E.; Newbold, T.; Sanchez-Ortiz, K.; Ferrier, S.; Purvis, A.

10.1101/311688 — ecology — Posted on 2018-04-30

45 Connectomics of the zebrafish’s lateral-line neuromast reveals wiring and miswiring in a simple microcircuit

Dow, E.; Jacobo, A.; Hossain, S.; Siletti, K.; Hudspeth, A. J.

10.1101/311506 — developmental biology — Posted on 2018-04-30

46 Semantic Disease Gene Embeddings (SmuDGE): phenotype-based disease gene prioritization without phenotypes

Alshahrani, M.; Hoehndorf, R.

10.1101/311449 — bioinformatics — Posted on 2018-04-30

47 A Recurrent Neural Network Approach for Automated Neural Tracing in Multispectral 3D Images

Yan, Y.; Sadis, B. V.; Roossien, D. H.; Corso, J. J.; Cai, D.

10.1101/230441 — neuroscience — Posted on 2018-04-30

48 Structurally Constrained Effective Brain Connectivity

Crimi, A.; Dodero, L.; Sambataro, F.; Murino, V.; Sona, D.

10.1101/310938 — neuroscience — Posted on 2018-04-30

49 Mechanistic Origins of Dynamic Instability in Filaments from the Phage Tubulin, PhuZ

Zehr, E. A.; Rohu, A.; Liu, Y.; Verba, K. A.; Pogliano, J.; Grigorieff, N.; Agard, D. A.

10.1101/311498 — cell biology — Posted on 2018-04-30

50 The Atomic Structure of the Microtubule-Nucleating γ-Tubulin Small Complex and its Implications for Regulation

Brilot, A. F.; Agard, D. A.

10.1101/310813 — biophysics — Posted on 2018-04-30

51 Autometa: Automated extraction of microbial genomes from individual shotgun metagenomes

Miller, I. J.; Rees, E. R.; Ross, J.; Miller, I.; Baxa, J.; Lopera, J.; Kerby, R. L.; Rey, F. E.; Kwan, J. C.

10.1101/251462 — bioinformatics — Posted on 2018-04-30

52 Efficient Merging of Genome Profile Alignments

Hennig, A.; Nieselt, K.

10.1101/309047 — bioinformatics — Posted on 2018-04-30

53 The mechanisms of gene regulatory networks constrain evolution: A lesson from synthetic circuits

Schaerli, Y.; Jimenez, A.; Duarte, J. M.; Mihajlovic, L.; Renggli, J.; Isalan, M.; Sharpe, J.; Wagner, A.

10.1101/184325 — systems biology — Posted on 2018-04-30

54 Genome-wide CRISPR-Cas9 screen in E. coli identifies design rules for efficient targeting

Gutierrez Soriano, B.; Wong Ng, J.; Cui, L.; Becavin, C.; Bikard, D.

10.1101/308148 — synthetic biology — Posted on 2018-04-30

55 Unsupervised clustering of temporal patterns in high-dimensional neuronal ensembles using a novel dissimilarity measure

Grossberger, L.; Battaglia, F. P.; Vinck, M.

10.1101/252791 — neuroscience — Posted on 2018-04-30

56 Physical activity predicts population-level age-related differences in frontal white matter

Strommer, J. M.; Davis, S. W.; Henson, R. N.; Tyler, L. K.; Cam-CAN, ; Campbell, K. L.

10.1101/311050 — neuroscience — Posted on 2018-04-30

57 Reconstitution of immune cell interactions in free-standing membranes

Jenkins, E.; Santos, A. M.; Felce, J. H.; Hatherley, D.; Dustin, M. L.; Davis, S. J.; Eggeling, C.; Sezgin, E.

10.1101/311399 — immunology — Posted on 2018-04-30

58 Precision Identification of Diverse Bloodstream Pathogens from the Gut Microbiome

Tamburini, F. B.; Andermann, T. M.; Tkachenko, E.; Senchyna, F.; Banaei, N.; Bhatt, A. S.

10.1101/310441 — genomics — Posted on 2018-04-30

59 Laboratory evolution from social to solitary behavior in the N2 reference strain is unnecessary for its fitness advantages

Zhao, Y.; Long, L.; Xu, W.; Campbell, R. F.; Large, E. L.; Greene, J. S.; McGrath, P. T.

10.1101/309997 — evolutionary biology — Posted on 2018-04-30

60 Single-molecule tracking in live Yersinia enterocolitica reveals distinct cytosolic complexes of injectisome subunits

Rocha, J.; Richardson, C.; Zhang, M.; Darch, C.; Cai, E.; Diepold, A.; Gahlmann, A.

10.1101/211318 — biophysics — Posted on 2018-04-30

61 Efficient computation of co-transcriptional RNA-ligand interaction dynamics

Wolfinger, M. T.; Flamm, C.; Hofacker, I. L.

10.1101/248450 — bioinformatics — Posted on 2018-04-30

62 Evidence of an Unusual Poly(A) RNA Signature Detected by High-throughput Chemical Mapping

Wellington-Oguri, R.; Fisker, E.; Wiley, M.; Zada, M.; Eterna Players,

10.1101/281147 — biochemistry — Posted on 2018-04-30

63 AMP-activated protein kinase is essential for the maintenance of energy levels during synaptic activation

Marinangeli, C.; Didier, S.; Ahmed, T.; Caillerez, R.; Domise, M.; Laloux, C.; Begard, S.; Carrier, S.; Colin, M.; Marchetti, P.; Ghesquiere, B.; Balschun, D.; Buee, L.; Kluza, J.; Vingtdeux, V.

10.1101/303867 — neuroscience — Posted on 2018-04-30

64 Identification of Polynucleotide Phosphorylase (PNPase) in Escherichia coli Involved in Persister Formation

Wu, N.; Zhang, Y.; Zhang, S.; Yuan, Y.; Liu, S.; Cui, P.; Zhang, W.; Zhang, Y.

10.1101/310987 — microbiology — Posted on 2018-04-30

65 Parallel Evolution of Key Genomic Features and Cellular Bioenergetics Across the Marine Radiation of a Bacterial Phylum

Getz, E. W.; Tithi, S. S.; Zhang, L.; Aylward, F. O.

10.1101/307454 — microbiology — Posted on 2018-04-30

66 A functional different immune capacity in cattle is associated with higher mastitis incidence

Lutterberg, K.; Kleinwort, K. J. H.; Hobmaier, B. F.; Hauck, S. M.; Nueske, S.; Scholz, A. M.; Deeg, C. A.

10.1101/311316 — immunology — Posted on 2018-04-30

67 Functional recruitment of dynamin requires multimeric interactions for efficient endocytosis

Rosendale, M.; Van, T. N.; Grillo-Bosch, D.; Gauthereau, I.; Claverol, S.; Choquet, D.; Sainlos, M.; Perrais, D.

10.1101/309245 — cell biology — Posted on 2018-04-30

68 The utility of Saw-scaled viper, Echis pyramidum, and Kenyan sand boa, Eryx colubrinus as bioindicator of heavy metals bioaccumulation in relation to DPTA soil extract and biological consequences.

Sleem, D. M. M.; Kadry, M. A. M.; Mohallal, E. M. E.; Marie, M. A.

10.1101/311357 — pharmacology and toxicology — Posted on 2018-04-30

69 Identification of small regulatory RNAs involved in persister formation

Zhang, S.; Liu, S.; Wu, N.; Zhang, W.; Zhang, Y.

10.1101/310631 — microbiology — Posted on 2018-04-30

70 Identification of novel genes including rpmF and yjjQ critical for Type II persister formation in Escherichia coli

Liu, S.; Wu, N.; Zhang, S.; Zhang, Y.; Zhang, W.; Zhang, Y.

10.1101/310961 — microbiology — Posted on 2018-04-30

71 Diversity of Culturable Endophytic bacteria from Wild and Cultivated Rice showed potential Plant Growth Promoting activities

Borah, M.; Das, S.; Boruah, H.; Boro, R.; Barooah, M.

10.1101/310797 — microbiology — Posted on 2018-04-30

72 Super-enhancers are transcriptionally more active and cell-type-specific than stretch enhancers

Khan, A.; Mathelier, A.; Zhang, X.

10.1101/310839 — genomics — Posted on 2018-04-30

73 Genome-wide Enhancer Maps Differ Significantly in Genomic Distribution, Evolution, and Function

Benton, M. L.; Talipineni, S. C.; Kostka, D.; Capra, J. A.

10.1101/176610 — genetics — Posted on 2018-04-30

74 Spc110 N-Terminal Domains Act Independently to Mediate Stable γ-Tubulin Small Complex Binding and γ-Tubulin Ring Complex Assembly

Lyon, A. S.; Zelter, A.; Viswanath, S.; Maxwell, A.; Johnson, R.; Yabut, K. C. B.; MacCoss, M.; Davis, T. N.; Muller, E.; Sali, A.; Agard, D. A.

10.1101/311027 — biochemistry — Posted on 2018-04-30

75 Genome Wide Identification Of Bacterial Genes Required For Plant Infection By Tn-Seq

Royet, K.; Parisot, N.; Rodrigue, A.; Gueguen, E.; Condemine, G.

10.1101/126896 — microbiology — Posted on 2018-04-30

76 Exact and approximate limit behaviour of the Yule tree’s cophenetic index

Bartoszek, K.

10.1101/120931 — evolutionary biology — Posted on 2018-04-30

77 Adult-born neurons maintain hippocampal cholinergic inputs and support working memory during aging

Kirshenbaum, G.; Robson, V. K.; Shansky, R. M.; Savage, L. M.; Leonardo, E. D.; Dranovsky, A.

10.1101/311423 — neuroscience — Posted on 2018-04-30

78 A natural variant and an engineered mutation in a GPCR promote DEET resistance in C. elegans

Dennis, E. J.; Dobosiewicz, M.; Jin, X.; Duvall, L. B.; Hartman, P. S.; Bargmann, C. I.; Vosshall, L. B.

10.1101/198705 — neuroscience — Posted on 2018-04-30

79 To B or not to B: Arsenophonus as a source of B-vitamins in whiteflies.

Santos-Garcia, D.; Juravel, K.; Freilich, S.; Zchori-Fein, E.; Latorre, A.; Moya, A.; Morin, S.; Silva, F. J.

10.1101/311076 — microbiology — Posted on 2018-04-30

80 Creating Standards for Evaluating Tumour Subclonal Reconstruction

Boutros, P. C.; Salcedo, A.; Tarabichi, M.; Espiritu, S. M. G.; Deshwar, A. G.; David, M.; Wilson, N. M.; Dentro, S.; Wintersinger, J. A.; Liu, L. Y.; Ko, M.; Sivanandan, S.; Zhang, H.; Zhu, K.; Ou Yang, T.-H.; Chilton, J. M.; Buchanan, A.; Lalansingh, C. M.; P'ng, C.; Anghel, C. V.; Umar, I.; Lo, B.; Simpson, J. T.; Stuart, J. M.; Anastassiou, D.; Guan, Y.; Ewing, A.; Ellrott, K.; Wedge, D. C.; Morris, Q. D.; Van Loo, P.; DREAM SMC-Het Participants,

10.1101/310425 — bioinformatics — Posted on 2018-04-30

81 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

Dekker, J. D.; Rhee, C.; Hu, Z.; Lee, B.-K.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Tucker, H. O.; Ippolito, G. C.

10.1101/310680 — immunology — Posted on 2018-04-30

82 Morphological variation and strain identification of insects using wings and I3S.

Vyas-Patel, N.; Mumford, J. D.

10.1101/309468 — ecology — Posted on 2018-04-30

83 Structural insights into the binding mechanism of Plasmodium falciparum exported Hsp40-Hsp70 chaperone pair

Behl, A.; Mishra, P. C.

10.1101/311191 — bioinformatics — Posted on 2018-04-30

84 To B or not to B: Arsenophonus as a source of B-vitamins in whiteflies.

Santos-Garcia, D.; Juravel, K.; Freilich, S.; Zchori-Fein, E.; Latorre, A.; Moya, A.; Morin, S.; Silva, F. J.

10.1101/311076 — microbiology — Posted on 2018-04-30

85 Diagnosis of Human Leptospirosis: High Resolution Melting Analysis for Direct Detection of Leptospira in the Early Stage of the Disease in a Clinical Setting

Esteves, L. M.; Bulhoes, S. M.; Branco, C. C.; Carreira, T.; Vieira, M. L.; Gomes-Solecki, M.; Mota-Vieira, L.

10.1101/311142 — microbiology — Posted on 2018-04-30

86 Quantifying protein oligomerization in living cells: A systematic comparison of fluorescent proteins

Dunsing, V.; Luckner, M.; Zühlke, B.; Petazzi, R.; Herrmann, A.; Chiantia, S.

10.1101/311175 — biophysics — Posted on 2018-04-30

87 NetSurfP-2.0: improved prediction of protein structural features by integrated deep learning

Klausen, M. S.; Jespersen, M. C.; Nielsen, H.; Jensen, K. K.; Jurtz, V. I.; Soenderby, C. K.; Sommer, M. O. A.; Winther, O.; Nielsen, M.; Petersen, B.; Marcatili, P.

10.1101/311209 — bioinformatics — Posted on 2018-04-30

88 Identifying Gene Expression Programs of Cell-type Identity and Cellular Activity with Single-Cell RNA-Seq

Kotliar, D.; Veres, A.; Nagy, M. A.; Tabrizi, S.; Hodis, E.; Melton, D. A.; Sabeti, P. C.

10.1101/310599 — bioinformatics — Posted on 2018-04-30

89 Cholesterol bound Plasmodium falciparum co-chaperone ‘PFA0660w’ complexes with major virulence factor ‘PfEMP1’ via chaperone ‘PfHsp70-x’

Behl, A.; Kumar, V.; Bisht, A.; Panda, J. J.; Hora, R.; Mishra, P. C.

10.1101/311134 — molecular biology — Posted on 2018-04-30

90 Inactivation of the monofunctional peptidoglycan glycosyltransferase SgtB allows Staphylococcus aureus to survive in the absence of lipoteichoic acid

Karinou, E.; Pazos, M.; Vollmer, W.; Grundling, A.

10.1101/311282 — microbiology — Posted on 2018-04-30

91 The choice of the environmental covariate affects the power to detect variation in reaction norm slopes

Gienapp, P.

10.1101/311217 — evolutionary biology — Posted on 2018-04-30

92 Home ground advantage: selection against dispersers promotes cryptic local adaptation in wild salmon

Mobley, K.; Granroth-Wilding, H.; Ellmen, M.; Vaha, J.-P.; Aykanat, T.; Johnston, S. E.; Orell, P.; Erkinaro, J.; Primmer, C. R.

10.1101/311258 — evolutionary biology — Posted on 2018-04-30

93 Silencing of the CSNK2β gene by siRNA inhibits invasiveness and growth of MDA-MB-231 cells

Karna, S. K. L.; Lone, B. A.; Ahmad, F.; Shahi, N.; Pokharel, Y. R.

10.1101/311092 — cancer biology — Posted on 2018-04-30

94 Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results

Liu, Y.; Mi, Y.; Mueller, T.; Kreibich, S.; Williams, E. G.; Van Drogen, A.; Borel, C.; Germain, P.-L.; Frank, M.; Bludau, I.; Mehnert, M.; Seifert, M.; Emmenlauer, M.; Sorg, I.; Bezrukov, F.; Bena, F. S.; Zhou, H.; Dehio, C.; Testa, G.; Saez-Rodriguez, J.; Antonarakis, S. E.; Hardt, W.-D.; Aebersold, R.

10.1101/307421 — systems biology — Posted on 2018-04-30

95 N-1-naphthylphthalamic acid stimulates tomato hypocotyl elongation, elevates ethylene levels and alters metabolic homeostasis

Nongmaithem, S.; Devulapalli, S.; Sreelakshmi, Y.; Sharma, R.

10.1101/311159 — plant biology — Posted on 2018-04-30

96 Biogenesis of a young, 22-nt microRNA in Phaseoleae species by precursor-programmed uridylation

Fei, Q.; Yu, Y.; Liu, L.; Zhang, Y.; Baldrich, P.; Dai, Q.; Chen, X.; Meyers, B.

10.1101/310920 — plant biology — Posted on 2018-04-30

97 An RNAi screen in human cell lines reveals conserved DNA damage repair pathways that mitigate formaldehyde sensitivity

Juarez, E.; Chambwe, N.; Tang, W.; Mitchell, A. D.; Owen, N.; Kumari, A.; Monnat, R. J.; McCullough, A.

10.1101/310730 — cell biology — Posted on 2018-04-30

98 Cerebellar nuclei neurons dictate growth of the cortex through developmental scaling of presynaptic Purkinje cells

Joyner, A. L.; Willett, R. T.; Wojcinski, A.; Bayin, N. S.; Lao, Z.; Stephen, D.; Dauber-Decker, K. L.; Wu, Z.; Tessier-Lavigne, M.; Saito, H.; Suzuki, N.

10.1101/310953 — developmental biology — Posted on 2018-04-30

99 DET1-mediated degradation of a SAGA-like deubiquitination module controls H2Bub homeostasis

Nassrallah, A.; Rougee, M.; Bourbousse, C.; Drevensek, S.; Fonseca, S.; Iniesto, E.; Ait-Mohamed, O.; Deton-Cabanillas, A.-F.; Zabulon, G.; Ahmed, I.; Stroebel, D.; Masson, V.; Lombard, B.; Eeckhout, D.; Gevaert, K.; Loew, D.; Genovesio, A.; Breyton, C.; de Jaeger, G.; Bowler, C.; Rubio, V.; Barneche, F.

10.1101/309732 — plant biology — Posted on 2018-04-30

100 Interdependence of EGFR with PTPs on juxtaposed membranes generates a growth factor sensing and responding network

Stanoev, A.; Mhamane, A.; Schuermann, K. C.; Grecco, H. E.; Stallaert, W.; Baumdick, M.; Brueggemann, Y.; Joshi, M. S.; Roda-Navarro, P.; Fengler, S.; Stockert, R.; Rossmannek, L.; Luig, J.; Koseska, A.; Bastiaens, P. I. H.

10.1101/309781 — systems biology — Posted on 2018-04-29

101 Asymmetric increases in the intensity of the green autofluorescence of ischemic stroke patients’ skin and fingernails: A novel diagnostic biomarker for ischemic stroke

Wu, D.; Zhang, M.; Tao, Y.; Li, Y.; Zhang, S.; Chen, X.; Ying, W.

10.1101/310904 — neuroscience — Posted on 2018-04-29

102 ovoD co-selection: a method for enriching CRISPR/Cas9-edited alleles in Drosophila

Ewen-Campen, B.; Perrimon, N.

10.1101/310854 — genetics — Posted on 2018-04-29

103 A Monte Carlo method for in silico modeling and visualization of Waddington’s epigenetic landscape with intermediate details

Zhang, X.; Chong, K. H.; Zheng, J.

10.1101/310771 — systems biology — Posted on 2018-04-29

104 Human 5′ UTR design and variant effect prediction from a massively parallel translation assay

Sample, P. J.; Wang, B.; Reid, D. W.; Presnyak, V.; McFadyen, I.; Morris, D. R.; Seelig, G.

10.1101/310375 — synthetic biology — Posted on 2018-04-29

105 Sexual maturation and embryonic development in octopus: use of energy and antioxidant defense mechanisms using Octopus mimus as a model.

Olivares, A.; Rodriguez-Fuentes, G.; Mascaro, M.; Sanchez, A.; Ortega, K.; Caamal-Monsreal, C.; Tremblay, N.; Rosas, C.

10.1101/310664 — physiology — Posted on 2018-04-29

106 U1 snRNP regulates chromatin retention of noncoding RNAs

Yin, Y.; Lu, J. Y.; Zhang, X.; Shao, W.; Xu, Y.; Li, P.; Hong, Y.; Zhang, Q. C.; Shen, X.

10.1101/310433 — molecular biology — Posted on 2018-04-29

107 Forces on nascent polypeptides during membrane insertion and translocation via the Sec translocon

Niesen, M.; Muller-Lucks, A.; Hedman, R.; von Heijne, G.; Miller, T. F.

10.1101/310698 — biophysics — Posted on 2018-04-29

108 Identifying high-priority proteins across the human diseasome using semantic similarity

Lau, E.; Venkatraman, V.; Thomas, C. T.; Van Eyk, J. E.; Lam, M. P. Y.

10.1101/309203 — bioinformatics — Posted on 2018-04-29

109 Cargo-Loading of Misfolded Proteins into Extracellular Vesicles: The Role of J Proteins

Pink, D.; Donnelier, J.; Lewis, J.; Braun, J. E. A.

10.1101/310219 — neuroscience — Posted on 2018-04-29

110 Classification of the gifted natural product producer Streptomyces roseofaciens sp. nov. by polyphasic taxonomy

van der Aart, L.; Nouinoui, I.; Kloosterman, A.; Ingual, J. M.; Willemse, J.; Goodfellow, M.; van Wezel, G.

10.1101/310888 — microbiology — Posted on 2018-04-29

111 Detection of succinate by intestinal tuft cells triggers a type 2 innate immune circuit

Nadjsombati, M. S.; McGinty, J. W.; Lyons-Cohen, M. R.; Pollack, J. L.; Nagana Gowda, G. A.; Erle, D. J.; Locksley, R. M.; Raftery, D.; von Moltke, J.

10.1101/310110 — immunology — Posted on 2018-04-29

112 Anthropogenic habitat alteration leads to rapid loss of adaptive variation and restoration potential in wild salmon populations

Thompson, T. Q.; Bellinger, R. M.; O'Rourke, S. M.; Prince, D. J.; Stevenson, A. E.; Rodrigues, A. T.; Sloat, M. R.; Speller, C. F.; Yang, D. Y.; Butler, V. L.; Banks, M. A.; Miller, M. R.

10.1101/310714 — genetics — Posted on 2018-04-29

113 Genome-wide DNA methylation patterns in Autism Spectrum Disorder and mitochondrial function.

Stathopoulos, S.; Gaujoux, R.; O'Ryan, C.

10.1101/310748 — genetics — Posted on 2018-04-29

114 High-throughput inverse toeprinting reveals the complete sequence dependence of ribosome-targeting antibiotics

Seip, B.; Sacheau, G.; Dupuy, D.; Innis, C. A.

10.1101/298794 — molecular biology — Posted on 2018-04-29

115 Sporulation-specific cell division defects in ylmE mutants of Streptomyces coelicolor are rescued by additional deletion of ylmD

Zhang, L.; Willemse, J.; Hoskisson, P. A.; van Wezel, G.

10.1101/214072 — microbiology — Posted on 2018-04-29

116 Transcriptome analysis in whole blood reveals increased microbial diversity in schizophrenia

M Olde Loohuis, L.; Mangul, S.; Ori, A.; Jospin, G.; Koslicki, D.; Yang, H. T.; Wu, T.; Boks, M. P.; Lomen-Hoerth, C.; Wiedau-Pazos, M.; Cantor, R.; M de Vos, W.; S Kahn, R.; Eskin, E.; Ophoff, R. A.

10.1101/057570 — microbiology — Posted on 2018-04-29

117 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

Dekker, J. D.; Rhee, C.; Hu, Z.; Lee, B.-K.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Tucker, H. O.; Ippolito, G. C.

10.1101/310680 — immunology — Posted on 2018-04-29

118 A Universal Temperature-Dependence of Mutational Fitness Effects

Berger, D.; Stangberg, J.; Walters, R. J.

10.1101/268011 — evolutionary biology — Posted on 2018-04-29

119 Seed predation increases from the Arctic to the Equator and from high to low elevations

Hargreaves, A. L.; Suarez, E.; Mehltreter, K.; Myers-Smith, I.; Vanderplank, S. E.; Slinn, H. L.; Vargas-Rodriguez, Y. L.; Haeussler, S.; David, S.; Munoz, J.; Almazan Nunez, R. C.; Loughnan, D.; Benning, J. W.; Moeller, D. A.; Brodie, J. F.; Thomas, H. J.; Morales M, P. A.

10.1101/304634 — ecology — Posted on 2018-04-29

120 Exome sequencing in families with severe mental illness identifies novel and rare variants in genes implicated in Mendelian neuropsychiatric syndromes

Ganesh, S.; Ahmed P, H.; Nadella, R. K.; More, R. P.; Seshadri, M.; Viswanath, B.; Rao, M.; Jain, S.; The ADBS consortium, ; Mukherjee, O.

10.1101/310821 — neuroscience — Posted on 2018-04-29

121 Catecholamine Challenge Uncovers Distinct Mechanisms For Direct Versus Indirect, But Not Social Versus Non-Social, Learning

Cook, J. L.; Swart, J. C.; Frobose, M. I.; Diaconescu, A.; Geurts, D. E. M.; den Ouden, H. E. M.; Cools, R.

10.1101/303982 — neuroscience — Posted on 2018-04-29

122 SMURF-seq for fast, multiplexed copy number profiling with long-read sequencers

Prabakar, R. K.; Xu, L.; Hicks, J.; Smith, A. D.

10.1101/310706 — genomics — Posted on 2018-04-29

123 BGEN: a binary file format for imputed genotype and haplotype data

Band, G.; Marchini, J.

10.1101/308296 — bioinformatics — Posted on 2018-04-29

124 Optimizing the identification of causal variants across varying genetic architectures in crops

Miao, C.; Yang, J.; Schnable, J. C.

10.1101/310391 — genomics — Posted on 2018-04-29

125 Bracketing phenotypic limits of mammalian hybridization

Savriama, Y.; Valtonen, M.; Kammonen, J.; Rastas, P.; Smolander, O.-P.; Lyyski, A.; Hakkinen, T. J.; Corfe, I. J.; Gerber, S.; Salazar-Ciudad, I.; Paulin, L.; Holm, L.; Loytynoja, A.; Auvinen, P.; Jernvall, J.

10.1101/310789 — evolutionary biology — Posted on 2018-04-29

126 Illuminating microbial metabolic activities in the dark deep ocean with metaproteomics

Xie, Z.-X.; Zhang, S.-F.; Zhang, H.; Kong, L.-F.; Lin, L.; Wang, D.

10.1101/310524 — microbiology — Posted on 2018-04-28

127 The MarR Family Regulator BmrR is involved in Bile Tolerance of Bifidobacterium longum BBMN68 via Controlling the Expression of an ABC-Transporter

Xu, Q.; Zhai, Z.; An, H.; Yang, Y.; Yin, J.; Wang, G.; Ren, F. Z.; Hao, Y.

10.1101/310508 — microbiology — Posted on 2018-04-28

128 High-density, long-lasting, and multi-region electrophysiological recordings using polymer electrode arrays

Chung, J. E.; Joo, H. R.; Fan, J. L.; Liu, D. F.; Barnett, A. H.; Chen, S.; Geaghan-Breiner, C.; Karlsson, M. P.; Karlsson, M.; Lee, K. Y.; Liang, H.; Magland, J. F.; Tooker, A. C.; Greengard, L. F.; Tolosa, V. M.; Frank, L. M.

10.1101/242693 — neuroscience — Posted on 2018-04-28

129 Real-time functional connectivity-based neurofeedback of amygdala-frontal pathways reduces anxiety

Zhao, Z.; Yao, S.; Li, K.; Sindermann, C.; Zhou, F.; Zhao, W.; Li, J.; Luehrs, M.; Goebel, R.; Kendrick, K.; Becker, B.

10.1101/308924 — clinical trials — Posted on 2018-04-28

130 Prenatal alcohol exposure and facial morphology in a UK cohort

Howe, L. J.; Sharp, G. C.; Hemani, G.; Zuccolo, L.; Richmond, S.; Lewis, S. J.

10.1101/302364 — epidemiology — Posted on 2018-04-28

131 Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

Dekker, J. D.; Rhee, C.; Hu, Z.; Lee, B.-K.; Lee, J.; Iyer, V. R.; Ehrlich, L. I. R.; Georgiou, G.; Tucker, H. O.; Ippolito, G. C.

10.1101/310680 — immunology — Posted on 2018-04-28

132 GnasR201C Induces Murine Pancreatic Cystic Neoplasms through Suppression of YAP1 Signaling and Transcriptional Reprogramming

Ideno, N.; Yamaguchi, H.; Ghosh, B.; Gupta, S.; Okumura, T.; Fisher, C. G.; Wood, L. D.; Singhi, A. D.; Nakamura, M.; Gutkind, J. S.; Maitra, A.

10.1101/310292 — cancer biology — Posted on 2018-04-28

133 Disturbance macroecology: integrating disturbance ecology and macroecology in different-age post-fire stands of a closed-cone pine forest as a case study

Newman, E. A.; Wilber, M. Q.; Kopper, K. E.; Moritz, M. A.; Falk, D. A.; McKenzie, D.; Harte, J.

10.1101/309419 — ecology — Posted on 2018-04-28

134 Investigating the effect of Target of Rapamycin kinase inhibition on the Chlamydomonas reinhardtii phosphoproteome: from known homologs to new targets

Werth, E. G.; McConnell, E. W.; Couso, I.; Perrine, Z.; Crespo, J. L.; Umen, J. G.; Hicks, L. M.

10.1101/310102 — plant biology — Posted on 2018-04-28

135 PII1: a protein involved in starch initiation that determines granule number and size in Arabidopsis chloroplast.

Vandromme, C.; Spriet, C.; Dauvillee, D.; Courseaux, A.; Putaux, J.-L.; Wychowski, A.; Facon, M.; D Hulst, C.; Wattebled, F.

10.1101/310003 — plant biology — Posted on 2018-04-28

136 Expectation of the intercept from bivariate LD score regression in the presence of population stratification

Yengo, L.; Yang, J.; Visscher, P. M.

10.1101/310565 — genetics — Posted on 2018-04-28

137 Limb bone scaling in hopping macropods and quadrupedal artiodactyls

Doube, M.; Felder, A. A.; Chua, M. Y.; Lodhia, K.; Kłosowski, M. M.; Hutchinson, J. R.; Shefelbine, S. J.

10.1101/256768 — evolutionary biology — Posted on 2018-04-28

138 Discovery of a new path for red blood cell generation in the mouse embryo

Pinheiro, I.; Vargel Bolukbasi, O.; Ganter, K.; Sabou, L. A.; Tew, V. K.; Bolasco, G.; Shvartsman, M.; Pavlovich, P. V.; Buness, A.; Nikolakopoulou, C.; Bergiers, I.; Kouskoff, V.; Lacaud, G.; Lancrin, C.

10.1101/309054 — developmental biology — Posted on 2018-04-28

139 The impact of fibronection stripe patterns on the cellular and nuclear morphology of fibroblasts

Mamaghani, P.; Donald, A.

10.1101/302687 — biophysics — Posted on 2018-04-28

140 EnTAP: Bringing Faster and Smarter Functional Annotation to Non-Model Eukaryotic Transcriptomes

Hart, A. J.; Ginzburg, S.; Xu, M.; Fisher, C. R.; Rahmatpour, N.; Mitton, J. B.; Paul, R.; Wegrzyn, J. L.

10.1101/307868 — bioinformatics — Posted on 2018-04-28

141 Deep learning reveals many more inter-protein residue-residue contacts than direct coupling analysis

Zhou, T.; Wang, S.; Xu, J.

10.1101/240754 — bioinformatics — Posted on 2018-04-28

142 Per-sample immunoglobulin germline inference from B cell receptor deep sequencing data

Ralph, D. K.; Matsen, F. A.

10.1101/220285 — bioinformatics — Posted on 2018-04-28

143 Mapping molecular datasets back to the brain regions they are extracted from: Remembering the native countries of hypothalamic expatriates and refugees

Khan, A. M.; Grant, A. H.; Martinez, A.; Burns, G. A.; Thatcher, B. S.; Anekonda, V. T.; Thompson, B. W.; Roberts, Z. S.; Moralejo, D. H.; Blevins, J. E.

10.1101/307652 — neuroscience — Posted on 2018-04-28

144 Solving for X: evidence for sex-specific autism biomarkers across multiple transcriptomic studies

Lee, S. C.; Quinn, T. P.; Lai, J.; Kong, S. W.; Hertz-Picciotto, I.; Glatt, S. J.; Crowley, T. M.; Venkatesh, S.; Nguyen, T.

10.1101/309518 — neuroscience — Posted on 2018-04-28

145 Studies on squalene biosynthesis and the standardization of its extraction methodology from Saccharomyces cerevisiae

Paramasivan, K.; Mutturi, S.; Rajagopal, K.

10.1101/309609 — microbiology — Posted on 2018-04-28

146 Discovery of a Streptococcus pneumoniae serotype 33F capsular polysaccharide locus that lacks wcjE and contains a wcyO pseudogene

Manna, S.; Dunne, E. M.; Ortika, B. D.; Pell, C.; Kama, M.; Russell, F. M.; Mungun, T.; Mulholland, E. K.; Hinds, J.; Satzke, C.

10.1101/308767 — microbiology — Posted on 2018-04-28

147 Whole-genome sequencing analysis of copy number variation (CNV) using low-coverage and paired-end strategies is efficient and outperforms array-based CNV analysis

Zhou, B.; Ho, S. S.; Zhang, X.; Pattni, R.; Haraksingh, R. R.; Urban, A. E.

10.1101/192310 — genomics — Posted on 2018-04-28

148 Senescence of multicellular individuals: imbalance of epigenetic and non-epigenetic information in histone modifications

Veloso, F. A.

10.1101/310300 — developmental biology — Posted on 2018-04-28

149 Anxiety induced by extra-hypothalamic BDNF deficiency instigates resistance to diet-induced obesity

Xie, X.; Yang, H.; An, J. J.; Liao, G.-Y.; Xu, Z.-X.; Tan, J.; Xu, B.

10.1101/309930 — physiology — Posted on 2018-04-28

150 A CRISPR/Cas9 based strategy to manipulate the Alzheimer’s amyloid pathway

Sun, J.; Carlson-Stevermer, J.; Das, U.; Shen, M.; Delenclos, M.; Snead, A.; Wang, L.; Loi, J.; Petersen, A.; Stockton, M.; Bhattacharyya, A.; Jones, M.; Sproul, A.; McLean, P.; Zhao, X.; Saha, K.; Roy, S.

10.1101/310193 — neuroscience — Posted on 2018-04-28

151 Regulation of evidence accumulation by pupil-linked arousal processes

Keung, W.; Hagen, T. A.; Wilson, R. C.

10.1101/309526 — neuroscience — Posted on 2018-04-28

152 Lactococcin B is inactivated by intrinsic proteinase PrtP digestion in Lactococcus lactis subsp. lactis BGMN1-501

Vukotic, G.; Polovic, N.; Mirkovic, N.; Jovcic, B.; Stanisavljevic, N.; Fira, D.; Kojic, M.

10.1101/309575 — microbiology — Posted on 2018-04-28

153 Molecular dynamics suggests antiviral compounds active against Dengue Virus show similar binding patterns to Zika Virus proteins

de Lima Neto, D. F.; Soares, A. P.; Pour, S. Z.; Ortiz, A. S.; Freire, C. M.; Neuhaus, P.; Bonafe, C. F.; Zanotto, P. M.

10.1101/309351 — microbiology — Posted on 2018-04-28

154 Gain of Function Analysis Reveals Non-Redundant Roles for the Yersinia pestis Type III Secretion System Effectors YopJ, YopT, and YpkA

Palace, S. G.; Proulx, M. K.; Szabady, R. L.; Goguen, J. D.

10.1101/310243 — microbiology — Posted on 2018-04-28

155 Cycles of gene expression and genome response during mammalian tissue regeneration

Rib, L.; Villeneuve, D.; Praz, V.; Hernandez, N.; Guex, N.; Herr, W.; CycliX Consortium,

10.1101/309989 — genomics — Posted on 2018-04-28

156 The Shared Genetic Basis of Educational Attainment and Cerebral Cortical Morphology

Ge, T.; Chen, C.-Y.; Doyle, A. E.; Vettermann, R.; Tuominen, L. J.; Holt, D. J.; Sabuncu, M. R.; Smoller, J. W.

10.1101/242776 — genetics — Posted on 2018-04-28

157 A European whitefish linkage map and its implications for understanding genome-wide synteny between salmonids following whole genome duplication

De-Kayne, R.; Feulner, P. G. D.

10.1101/310136 — evolutionary biology — Posted on 2018-04-28

158 The 2017 plague outbreak in Madagascar: data descriptions and epidemic modelling

Nguyen, V. K.; Parra-Rojas, C.; Hernandez-Vargas, E.

10.1101/247569 — epidemiology — Posted on 2018-04-28

159 Map segmentation, automated model-building and their application to the Cryo-EM Model Challenge

Terwilliger, T.; Adams, P. D.; Afonine, P.; Sobolev, O. V.

10.1101/310268 — biophysics — Posted on 2018-04-28

160 Structural basis for relief of the sarcoplasmic reticulum Ca2+-ATPase inhibition by phospholamban at saturating Ca2+ conditions

Fernandez-de Gortari, E.; Espinoza-Fonseca, L. M.

10.1101/310607 — biophysics — Posted on 2018-04-28

161 Helicase Promotes Replication Re-initiation from an RNA Transcript

Sun, B.; Singh, A.; Sultana, S.; Inman, J.; Patel, S.; Wang, M.

10.1101/310235 — biophysics — Posted on 2018-04-28

162 How epigenome drives chromatin folding and dynamics, insights from efficient coarse-grained models of chromosomes

Ghosh, S. K.; Jost, D.

10.1101/200584 — biophysics — Posted on 2018-04-28

163 CAGEfightR: Cap Analysis of Gene Expression (CAGE) in R/Bioconductor

Thodberg, M.; Thieffry, A.; Vitting-Seerup, K.; Andersson, R.; Sandelin, A.

10.1101/310623 — bioinformatics — Posted on 2018-04-28

164 Identification of midbrain neurons essential for vocal communication

Tschida, K.; Michael, V.; Han, B.-X.; Zhao, S.; Sakurai, K.; Mooney, R.; Wang, F.

10.1101/310250 — neuroscience — Posted on 2018-04-28

165 FMRI processing with AFNI: Some comments and corrections on \"Exploring the Impact of Analysis Software on Task fMRI Results\"

Taylor, P. A.; Chen, G.; Glen, D. R.; Rajendra, J. K.; Reynolds, R. C.; Cox, R. W.

10.1101/308643 — neuroscience — Posted on 2018-04-28

166 Octapeptin C4 Induces Less Resistance and Novel Mutations in an Epidemic Carbapenemase-producing Klebsiella pneumoniae ST258 Clinical Isolate Compared to Polymyxins

Pitt, M.; Cao, M. D.; Butler, M.; Ramu, S.; Ganesamoorthy, D.; Blaskovich, M.; Coin, L.; Cooper, M.

10.1101/309674 — microbiology — Posted on 2018-04-28

167 The conservation landscape of the human ribosomal RNA gene repeats

Agrawal, S.; Ganley, A. R. D.

10.1101/242602 — genomics — Posted on 2018-04-28

168 Rescue of a developmental arrest caused by a C. elegans heat-shock transcription-factor mutation by loss of ribosomal S6-kinase activity

Chisnell, P. J. D.; Parenteau, T. R.; Tank, E. M.; Ashrafi, K.; Kenyon, C.

10.1101/310086 — genetics — Posted on 2018-04-28

169 Corals sustain growth but not skeletal density across the Florida Keys Reef Tract despite ongoing warming

Rippe, J.; Baumann, J.; De Leener, D.; Aichelman, H.; Friedlander, E.; Davies, S.; Castillo, K.

10.1101/310037 — ecology — Posted on 2018-04-28

170 Tricellular junction proteins promote disentanglement of daughter and neighbour cells during epithelial cytokinesis

Wang, Z.; Bosveld, F.; Bellaiche, Y.

10.1101/309922 — developmental biology — Posted on 2018-04-28

171 A network of epigenomic and transcriptional cooperation encompassing an epigenomic master regulator in cancer

Wilson, S.; Filipp, F. V.

10.1101/309484 — systems biology — Posted on 2018-04-28

172 HDAC11 Deficiency Prevents High-Fat Diet-Induced Obesity and Metabolic Syndrome

Sun, L.; Marin De Evsikova, C.; Bian, K.; Achille, A.; Telles, E.; Seto, E.

10.1101/310383 — molecular biology — Posted on 2018-04-28

173 Combination attenuation offers strategy for live-attenuated coronavirus vaccines

Menachery, V. D.; Gralinski, L.; Mitchell, H. D.; Dinnon, K.; Leist, S. R.; Yount, B.; McAnarney, E. T.; Graham, R.; Waters, K. M.; Baric, R. S.

10.1101/309591 — microbiology — Posted on 2018-04-28

174 Introducing ribosomal tandem repeat barcoding for fungi

Wurzbacher, C.; Larsson, E.; Bengtsson-Palme, J.; Van den Wyngaert, S.; Svantesson, S.; Kristiansson, E.; Kagami, M.; Nilsson, R. H.

10.1101/310540 — genetics — Posted on 2018-04-28

175 Morphological variation and strain identification of insects using wings and I3S.

Vyas-Patel, N.; Mumford, J. D.

10.1101/309468 — ecology — Posted on 2018-04-28

176 A consistent picture of TRPV1 activation emerges from molecular simulations and experiments

Kasimova, M.; Yazici, A.; Yudin, Y.; Granata, D.; Klein, M. L.; Rohacs, T.; Carnevale, V.

10.1101/310151 — biophysics — Posted on 2018-04-28

177 DsbA is a switchable mechanical chaperone

Haldar, S.; Eckels, E. C.; Echelman, D. J.; Rivas Pardo, J. A.; Fernandez, J. M.

10.1101/310169 — biophysics — Posted on 2018-04-28

178 Isopeptide-Blocker Impairs the Mechanics of Recently Translated Pilin Proteins

Rivas-Pardo, J. A.; Tapia-Rojo, R.; Badilla, C. L.; Fernandez, J. M.

10.1101/310227 — biophysics — Posted on 2018-04-28

179 Behavioral repeatability and foraging performance in wild free-flying nectarivorous bats (Glossophaga commissarisi)

Nachev, V.; Winter, Y.

10.1101/309971 — animal behavior and cognition — Posted on 2018-04-28

180 Buffering gene expression noise by microRNA based feedforward regulation

Bokes, P.; Hojcka, M.; Singh, A.

10.1101/310656 — systems biology — Posted on 2018-04-28

181 Exploring sex differences in the prevention of ethanol drinking by naltrexone in dependent rats during abstinence

Matzeu, A.; Terenius, L.; Martin-Fardon, R.

10.1101/310334 — neuroscience — Posted on 2018-04-28

182 Bacillus cereus HS24 Suppresses Conidia Germination of Magnaporthe oryzae by Inhibiting the Ca2+ Signaling Pathway

Huang, W.; Liu, X.; Zhou, X.; Chen, Y.; Li, Y.; Liu, H.-x.

10.1101/310516 — microbiology — Posted on 2018-04-28

183 Small-scale soil microbial community heterogeneity linked to landforms on King George Island, maritime Antarctica

Zhang, Y.; Lu, L.; Chang, X.; Jiang, F.; Gao, X.-D.; Peng, F.

10.1101/310490 — microbiology — Posted on 2018-04-28

184 Single cell RNA sequencing reveals a novel, microglia-like cell type in cerebrospinal fluid during virologically suppressed HIV

Farhadian, S.; Mehta, S.; Zografou, C.; Pappalardo, J.; Chiarella, J.; Hafler, D.; Spudich, S.

10.1101/310128 — immunology — Posted on 2018-04-28

185 Hydrogen-deuterium exchange coupled to top- and middle-down mass spectrometry enables high-resolution measurements of histone tail dynamics before and after nucleosome assembly

Karch, K. R.; Coradin, M.; Zandarashvili, L.; Kan, Z.-Y.; Gerace, M.; Englander, S. W.; Black, B. E.; Garcia, B. A.

10.1101/310177 — biochemistry — Posted on 2018-04-28

186 Multi-omics approach identifies novel pathogen-derived prognostic biomarkers in patients with Pseudomonas aeruginosa bloodstream infection

Willmann, M.; Goettig, S.; Bezdan, D.; Macek, B.; Velic, A.; Marschal, M.; Vogel, W.; Flesch, I.; Markert, U.; Schmidt, A.; Kuebler, P.; Haug, M.; Javed, M.; Jentzsch, B.; Oberhettinger, P.; Schuetz, M.; Bohn, E.; Sonnabend, M.; Klein, K.; Autenrieth, I.; Ossowski, S.; Schwarz, S.; Peter, S.

10.1101/309898 — microbiology — Posted on 2018-04-28

187 High-throughput chromatin accessibility profiling at single-cell resolution

Mezger, A.; Klemm, S.; Mann, I.; Brower, K.; Mir, A.; Bostick, M.; Farmer, A.; Fordyce, P.; Linnarsson, S.; Greenleaf, W.

10.1101/310284 — genomics — Posted on 2018-04-28

188 The Genome of the Human Pathogen Candida albicans is Shaped by Mutation and Cryptic Sexual Recombination

Wang, J. M.; Bennett, R. J.; Anderson, M. Z.

10.1101/310201 — genomics — Posted on 2018-04-28

189 Evolutionary adaptability linked to length variation in short genic tandem repeats

Reinar, W. B.; Knutsen, J. B.; Jentoft, S.; Torresen, O. K.; Butenko, M. A.; Jakobsen, K. S.

10.1101/310045 — evolutionary biology — Posted on 2018-04-28

190 The landscape of selection in 551 Esophageal Adenocarcinomas defines genomic biomarkers for the clinic

Frankell, A. M.; Jammula, S.; Contino, G.; Killcoyne, S. S.; Abbas, S.; Perner, J.; Bower, L.; Devonshire, G.; Grehan, N.; Mok, J.; O'Donovan, M.; Macrae, S.; Tavare, S.; Fitzgerald, R. C.; the Oesophageal Cancer Clinical and Molecular Stratification (OCCAMS) Consortium,

10.1101/310029 — cancer biology — Posted on 2018-04-28

191 A Magnetic Head Design for Manipulating Single Proteins with Force

Tapia-Rojo, R.; Eckels, E. C.; Fernandez, J. M.

10.1101/310060 — biophysics — Posted on 2018-04-28

192 Clairvoyante: a multi-task convolutional deep neural network for variant calling in Single Molecule Sequencing

Luo, R.; Sedlazeck, F. J.; Lam, T.-W.; Schatz, M.

10.1101/310458 — bioinformatics — Posted on 2018-04-28

193 Creating Standards for Evaluating Tumour Subclonal Reconstruction

Boutros, P. C.; Salcedo, A.; Tarabichi, M.; Espiritu, S. M. G.; Deshwar, A. G.; David, M.; Wilson, N. M.; Dentro, S.; Wintersinger, J. A.; Liu, L. Y.; Ko, M.; Sivanandan, S.; Zhang, H.; Zhu, K.; Yang, T.-H.; Chilton, J. M.; Buchanan, A.; Lalansingh, C. M.; P'ng, C.; Anghel, C. V.; Umar, I.; Lo, B.; Simpson, J. T.; Stuart, J. M.; Anastassiou, D.; Guan, Y.; Ewing, A.; Ellrott, K.; Wedge, D. C.; Morris, Q. D.; Van Loo, P.; DREAM SMC-Het Participants,

10.1101/310425 — bioinformatics — Posted on 2018-04-28

194 Fast and global detection of periodic sequence repeats in large genomic resources

Mori, H.; Evans-Yamamoto, D.; Ishiguro, S.; Tomita, M.; Yachie, N.

10.1101/309039 — bioinformatics — Posted on 2018-04-28

195 Not so proportional after all?

Hope, T. M. H.; Friston, K.; Price, C. J.; Leff, A. P.; Rotshtein, P.; Bowman, H.

10.1101/306514 — neuroscience — Posted on 2018-04-28

196 AAV-mediated progranulin delivery to a mouse model of progranulin deficiency causes T cell-mediated hippocampal degeneration

Amado, D. A.; Rieders, J. M.; Diatta, F.; Hernandez-Con, P.; Singer, A.; Zhang, J.; Lancaster, E.; Davidson, B. L.; Chen-Plotkin, A. S.

10.1101/308692 — neuroscience — Posted on 2018-04-27

197 Joint single-cell DNA accessibility and protein epitope profiling reveals environmental regulation of epigenomic heterogeneity

Chen, X.; Litzenburger, U.; Wei, Y.; Schep, A. N.; LaGory, E. L.; Choudhry, H.; Giaccia, A. J.; Greenleaf, W. J.; Chang, H.

10.1101/310359 — genomics — Posted on 2018-04-27

198 Site-specific transgenesis of the D. melanogaster Y-chromosome using CRISPR/Cas9

Buchman, A.; Akbari, O.

10.1101/310318 — genetics — Posted on 2018-04-27

199 Pharmacophore-guided discovery of CDC25 inhibitors causing cell cycle arrest and cell death

Kabakci, Z.; Kaeppeli, S.; Cozza, G.; Cantu, C.; Koenig, C.; Toggweiler, J.; Gentili, C.; Ribaudo, G.; Zagotto, G.; Basler, K.; Pinna, L. A.; Ferrari, S.

10.1101/309914 — cancer biology — Posted on 2018-04-27

200 Transcriptome-wide association studies accounting for colocalization using Egger regression

Barfield, R.; Feng, H.; Gusev, A.; Wu, L.; Zheng, W.; Pasaniuc, B.; Kraft, P.

10.1101/223263 — epidemiology — Posted on 2018-04-27

201 Autotransporter secretion exploits the bacterial actin-homologue

Ashawesh, M.; Markus, R.; Penfold, C.; Hardie, K.

10.1101/305441 — microbiology — Posted on 2018-04-27

202 Temperature drives Zika virus transmission: evidence from empirical and mathematical models

Tesla, B.; Demakovsky, L. R.; Mordecai, E. A.; Ryan, S. J.; Bonds, M. H.; Ngonghala, C. N.; Brindley, M. A.; Murdock, C. C.

10.1101/259531 — ecology — Posted on 2018-04-27

203 Extreme Amyloid Polymorphism in Staphylococcus aureus Virulent PSMα Peptides

Salinas, N.; Colletier, J.-P.; Moshe, A.; Landau, M.

10.1101/309062 — biochemistry — Posted on 2018-04-27

204 Deep learning reveals many more inter-protein residue-residue contacts than direct coupling analysis

Zhou, T.; Wang, S.; Xu, J.

10.1101/240754 — bioinformatics — Posted on 2018-04-27

205 Interaction of BIR2/3 of XIAP with E2F1/Sp1 Activates MMP2 and Bladder Cancer Invasion by Inhibiting Src Translation

Huang, C.; Xu, J.; Hua, X.; Yang, R.

10.1101/309765 — cancer biology — Posted on 2018-04-27

206 Circulating microRNA biomarkers for metastatic disease in neuroblastoma patients

Zeka, F.; Van Goethem, A.; Vanderheyden, K.; Demuynck, F.; Lammens, T.; Decock, A.; Helsmoortel, H. H.; Vermeulen, J.; Noguera, R.; Berbegall, A. P.; Combaret, V.; Schleiermacher, G.; Laureys, G.; Schramm, A.; Schulte, J. H.; Rahmann, S.; Bienertova Vasku, J.; Mazanek, P.; Jeison, M.; Ash, S.; Hogarty, M. D.; Moreno-Smith, M.; Barbieri, E.; Shohet, J.; Berthold, F.; Speleman, F.; Fischer, M.; De Preter, K.; Mestdagh, P.; Vandesompele, J.

10.1101/309823 — cancer biology — Posted on 2018-04-27

207 National and Regional Influenza-Like-Illness Forecasts for the USA

Ben-Nun, M.; Riley, P.; Turtle, J.; Bacon, D.; Riley, S.

10.1101/309021 — epidemiology — Posted on 2018-04-27

208 Population-level HIV incidence estimates using a combination of synthetic cohort and recency biomarker approaches in KwaZulu-Natal, South Africa

Grebe, E.; Welte, A.; Johnson, L. F.; van Cutsem, G.; Puren, A.; Ellman, T.; Etard, J.-F.; Consortium for the Evaluation and Performance of HIV Incidence Assays (CEPHIA), ; Huerga, H.

10.1101/306464 — epidemiology — Posted on 2018-04-27

209 YAMDA: thousandfold speedup of EM-based motif discovery using deep learning libraries and GPU

Quang, D.; Guan, Y.; Parker, S.

10.1101/309872 — bioinformatics — Posted on 2018-04-27

210 Differentiation of vegetative cells into spores: a kinetic model applied to Bacillus subtilis

Gauvry, E.; Mathot, A.-G.; Couvert, O.; Leguerinel, I.; Jules, M.; Coroller, L.

10.1101/309617 — microbiology — Posted on 2018-04-27

211 Human stem cell resources are an inroad to Neandertal DNA functions

Dannemann, M.; Vernot, B.; Paabo, S.; Kelso, J.; Camp, J. G.

10.1101/309658 — evolutionary biology — Posted on 2018-04-27

212 Colistin resistance prevalence in Escherichia coli from domestic animals in intensive breeding farms of Jiangsu Province, China

Zhang, X.; Zhang, B.; Yu, Z.; Guo, Y.; Wang, J.; Zhao, P.; Liu, J.; He, K.

10.1101/307983 — epidemiology — Posted on 2018-04-27

213 Challenges in estimating the impact of vaccination with sparse data

Shioda, K.; Schuck-Paim, C.; Taylor, R. J.; Lustig, R.; Simonsen, L.; Warren, J. L.; Weinberger, D. M.

10.1101/302224 — epidemiology — Posted on 2018-04-27

214 Whole genome analysis of local Kenyan and global sequences unravels the epidemiological and molecular evolutionary dynamics of RSV genotype ON1 strains

Otieno, J. R.; Kamau, E. M.; Oketch, J. W.; Ngoi, J. M.; Gichuki, A. M.; Binter, S.; Otieno, G. P.; Ngama, M.; Agoti, C. N.; Cane, P. A.; Kellam, P.; Cotten, M.; Lemey, P.; Nokes, D. J.

10.1101/309187 — epidemiology — Posted on 2018-04-27

215 Association of intrauterine alcohol exposure and offspring depression:A negative control analysis of maternal and partner consumption.

Easey, K. E.; Timpson, N. J.; Munafo, M. R.

10.1101/307462 — epidemiology — Posted on 2018-04-27

216 An examination of multivariable Mendelian randomization in the single sample and two-sample summary data settings.

Sanderson, E.; Davey Smith, G.; Windmeijer, F.; Bowden, J.

10.1101/306209 — epidemiology — Posted on 2018-04-27

217 Microcrystalline hydroxyapatite is not inferior to fluorides in clinical caries prevention: a randomized, double-blind, non-inferiority trial

Schlagenhauf, U.; Kunzelmann, K.-H.; Hannig, C.; May, T. W.; Hoesl, H.; Gratza, M.; Viergutz, G.; Nazet, M.; Schamberger, S.; Proff, P.

10.1101/306423 — clinical trials — Posted on 2018-04-27

218 Temporal Dynamics of the Origin and Domestication of Sweet Potato and Implications for Dispersal to Polynesia

Scotland, R. W.; Munoz, P.; Carruthers, T.

10.1101/309799 — plant biology — Posted on 2018-04-27

219 Broad-spectrum adaptive antibiotic resistance associated with Pseudomonas aeruginosa mucin-dependent surfing motility

Sun, E.; Gill, E. E.; Falsafi, R.; Yeung, A. T. Y.; Liu, S.; Hancock, R. E. W.

10.1101/309625 — microbiology — Posted on 2018-04-27

220 Inter-species conservation of organisation and function between non-homologous regional centromeres

Tong, P.; Pidoux, A. L.; Toda, N. R.; Ard, R.; Berger, H.; Shukla, M.; Torres-Garcia, J.; Mueller, C. A.; Nieduszynski, C. A.; Allshire, R. C.

10.1101/309815 — genomics — Posted on 2018-04-27

221 Novel autotrophic organisms contribute significantly to the internal carbon cycling potential of a boreal lake

Peura, S.; Buck, M.; Aalto, S. L.; Morales, S. E.; Nykänen, H.; Eiler, A.

10.1101/309633 — ecology — Posted on 2018-04-27

222 Seasonal temperature variation influences climate suitability for dengue, chikungunya, and Zika transmission

Huber, J. H.; Childs, M. L.; Caldwell, J. M.; Mordecai, E. A.

10.1101/230383 — ecology — Posted on 2018-04-27

223 A Hierarchical Clustering Algorithm Based on Silhouette Index for Cancer Subtype Discovery from Omics Data

Nidheesh, N.; Nazeer, K. A. A.; Ameer, P. M.

10.1101/309716 — bioinformatics — Posted on 2018-04-27

224 The histone chaperone FACT modulates nucleosome structure by tethering its components

Wang, T.; Liu, Y.; Edwards, G. B.; Krzizike, D. D.; Scherman, H.; Luger, K.

10.1101/309708 — biochemistry — Posted on 2018-04-27

225 Network structure of the human musculoskeletal system shapes neural interactions on multiple timescales

Kerkman, J. N.; Daffertshofer, A.; Gollo, L.; Breakspear, M.; Boonstra, T. W.

10.1101/181818 — neuroscience — Posted on 2018-04-27

226 A speed-fidelity trade-off determines the mutation rate and virulence of an RNA virus

Fitzsimmons, W.; Woods, R. J.; McCrone, J. T.; Woodman, A.; Arnold, J. J.; Yennawar, M.; Evans, R.; Cameron, C. E.; Lauring, A. S.

10.1101/309880 — microbiology — Posted on 2018-04-27

227 Evolution of the latitudinal diversity gradient in the hyperdiverse ant genus Pheidole

Economo, E. P.; Huang, J.-P.; Fischer, G.; Sarnat, E. M.; Narula, N.; Janda, M.; Guenard, B.; Longino, J. T.; Knowles, L. L.

10.1101/295386 — evolutionary biology — Posted on 2018-04-27

228 Global immune fingerprinting in glioblastoma reveals immune-suppression signatures associated with prognosis

Alban, T. J.; Alvarado, A. G.; Sorensen, M. D.; Bayik, D.; Volovetz, J.; Serbinowski, E.; Mulkearn-Hubert, E.; Maksim, S.; Hale, J. S.; Onzi, G. R.; McGraw, M.; Huang, P.; Grabowski, M. M.; Wathen, C. A.; Radivoyevitch, T.; Kornblum, H. I.; Kristensen, B. W.; Vogelbaum, M. A.; Lathia, J. D.

10.1101/309807 — cancer biology — Posted on 2018-04-27

229 Sexual antagonism exerts evolutionarily persistent genomic constraints on sexual differentiation in Drosophila melanogaster

Hill, M. S.; Ruzicka, F.; Fuentes, S.; Collet, J. M.; Morrow, E. H.; Fowler, K.; Reuter, M.

10.1101/117176 — evolutionary biology — Posted on 2018-04-27

230 Temporal development of Drosophila embryos is highly robust across a wide temperature range

Chong, J.; Amourda, C.; Saunders, T. E.

10.1101/309724 — developmental biology — Posted on 2018-04-27

231 Claudin-4 Reconstituted in Unilamellar Vesicles is Sufficient to Form Tight Interfaces that Partition Membrane Proteins

Belardi, B.; Son, S.; Vahey, M. D.; Wang, J.; Hou, J.; Fletcher, D. A.

10.1101/309856 — cell biology — Posted on 2018-04-27

232 Construction of a novel phagemid to produce custom DNA origami scaffolds

Nafisi, P. M.; Aksel, T.; Douglas, S. M.

10.1101/309682 — biophysics — Posted on 2018-04-27

233 Deep learning achieves super-resolution in fluorescence microscopy

Wang, H.; Rivenson, Y.; Jin, Y.; Wei, Z.; Gao, R.; Gunaydin, H.; Bentolila, L.; Ozcan, A.

10.1101/309641 — bioengineering — Posted on 2018-04-27

234 HDGF supports anti-apoptosis and pro-fibrosis in pancreatic stellate cells of pancreatic cancer

Chen, Y.-T.; Li, C.-F.; Wang, T.-W.; Chang, T.-H.; Hsu, T.-P.; Chi, J.-Y.; Hsiao, Y.-W.; Wang, J.-M.

10.1101/272542 — cancer biology — Posted on 2018-04-27

235 Prognostic models for Ebola virus disease derived from data collected at five treatment units in Sierra Leone and Liberia: performance, external validation, and risk visualization

Colubri, A.; Levine, A. C.; Siakor, M.; Wolfman, V.; Hartley, M.-A.; Sesay, T.; Felix, A.; Sabeti, P. C.

10.1101/294587 — bioinformatics — Posted on 2018-04-27

236 Cascaded Processing of Amplitude Modulation for Natural Sound Recognition

Koumura, T.; Terashima, H.; Furukawa, S.

10.1101/308999 — neuroscience — Posted on 2018-04-27

237 Accurate Nonlinear Mapping between MNI Volumetric and FreeSurfer Surface Coordinate Systems

Wu, J.; Ngo, G. H.; Greve, D.; Li, J.; He, T.; Fischl, B.; Eickhoff, S. B.; Yeo, B. T. T.

10.1101/302794 — neuroscience — Posted on 2018-04-27

238 NLMR and landscapetools: An integrated environment for simulating and modifying neutral landscape models in R

Sciaini, M.; Fritsch, M.; Scherer, C.; Simpkins, C. E.

10.1101/307306 — ecology — Posted on 2018-04-27

239 A rapid and robust method for single cell chromatin accessibility profiling

Chen, X.; Natarajan, K. N.; Teichmann, S. A.

10.1101/309831 — genomics — Posted on 2018-04-27

240 The trade-off between neural computation and oscillatory coordination.

Peterson, E. J.; Voytek, B.

10.1101/309427 — neuroscience — Posted on 2018-04-27

241 Inferring the ancestry of parents and grandparents from genetic data

Pei, J.; Nielsen, R.; Wu, Y.

10.1101/308494 — genetics — Posted on 2018-04-27

242 A conservation assessment of the freshwater gastropods of South Dakota based on historical records and recent observations

Stephen, B. J.

10.1101/309385 — ecology — Posted on 2018-04-27

243 Intron retention as a novel source of cancer neoantigens

Smart, A. C.; Margolis, C. A.; Pimentel, H.; He, M. X.; Miao, D.; Adeegbe, D.; Fugmann, T.; Wong, K. K.; Van Allen, E. M.

10.1101/309450 — cancer biology — Posted on 2018-04-27

244 Assignment of the resting state of the secondary active transporter BetP by integrating spectroscopic measurements and molecular simulations

Leone, V.; Waclawska, I.; Koshy, C.; Kossman, K.; Sharma, M.; Prisner, T. F.; Ziegler, C.; Endeward, B.; Forrest, L. R.

10.1101/307710 — biophysics — Posted on 2018-04-27

245 CRISPRCloud2: A cloud-based platform for deconvoluting CRISPR screen data

Jeong, H.-H.; Kim, S. Y.; Rousseaux, M. W. C.; Zoghbi, H. Y.; Liu, Z.

10.1101/309302 — bioinformatics — Posted on 2018-04-27

246 From Synchrony to Asynchrony: Cerebellar-Basal Ganglia Functional Circuits in Young and Older Adults

Hausman, H. K.; Jackson, T. B.; Goen, J. R.; Bernard, J.

10.1101/309344 — neuroscience — Posted on 2018-04-27

247 On the problem of spike-wave discharge detection by humans and machines.

Pfammatter, J. A.; Maganti, R. K.; Jones, M. V.

10.1101/309146 — neuroscience — Posted on 2018-04-27

248 Relative sensitivity of explicit re-aiming and implicit motor adaptation

Hutter, S. A.; Taylor, J. A.

10.1101/308510 — neuroscience — Posted on 2018-04-27

249 Azithromycin resistance through interspecific acquisition of an epistasis dependent efflux pump component and transcriptional regulator in Neisseria gonorrhoeae

Wadsworth, C. B.; Arnold, B. J.; Sater, M. R.; Grad, Y. H.

10.1101/309294 — microbiology — Posted on 2018-04-27

250 A decay effect of bacterial growth rate associated with genome reduction

Tsuchiya, K.; Cao, Y.-Y.; Kurokawa, M.; Ashino, K.; Yomo, T.; Ying, B.-W.

10.1101/308817 — microbiology — Posted on 2018-04-27

251 Evolution of Environmentally-Enforced, Repeat Protein Topology in the Outer Membrane

Franklin, M. W.; Nepomnyaciy, S.; Feehan, R.; Ben-Tal, N.; Kolodny, R.; Slusky, J.

10.1101/309393 — biophysics — Posted on 2018-04-27

252 Construct validity of five sentiment analysis methods in the text of encounter notes of patients with critical illness

Weissman, G. E.; Ungar, L. H.; Harhay, M. O.; Courtright, K. R.; Halpern, S. D.

10.1101/309195 — bioinformatics — Posted on 2018-04-27

253 Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides

Chou, S. Z.; Pollard, T. D.

10.1101/309534 — biochemistry — Posted on 2018-04-27

254 Ataxin-7 and non-stop coordinate SCAR protein levels, subcellular localization, and actin cytoskeleton organization

Cloud, V.; Momtahan, E.; Jack, J. L.; Leiva, E.; Rapp, S. R.; Miller, S. A.; Holsapple, D.; Shelton, L. G.; Pierce, R. A.; Zhang, Y.; Florens, L.; Washburn, M. P.; Mohan, R. D.

10.1101/309476 — cell biology — Posted on 2018-04-27

255 PP2C phosphatases promote autophagy by dephosphorylation of the Atg1 complex

Memisoglu, G.; Eapen, V. V.; Haber, J. E.

10.1101/309500 — cell biology — Posted on 2018-04-27

256 Stalk-mediated communication in the dynein motor domain

Niekamp, S.; Coudray, N.; Zhang, N.; Vale, R. D.; Bhabha, G.

10.1101/309179 — biochemistry — Posted on 2018-04-27

257 Experimental increases in glucocorticoids alter function of the neuroendocrine stress axis in wild red squirrels without negatively impacting survival and reproduction

van Kesteren, F.; Delehanty, B.; Westrick, S. E.; Palme, R.; Boonstra, R.; Lane, J. E.; Boutin, S.; McAdam, A. G.; Dantzer, B.

10.1101/309278 — zoology — Posted on 2018-04-26

258 Fungal Bioaerosols at Five Dairy Farms: A Novel Approach to Describe Workers Exposure

Mbareche, H.; Veillette, M.; Bilodeau, G. J.; Duchaine, C.

10.1101/308825 — molecular biology — Posted on 2018-04-26

259 Interspecies DNA acquisition by a naturally competent Acinetobacter baumannii strain

Traglia, G. M.; Place, K.; Dotto, C.; Fernandez, J. S.; dos Santos Bahiense, C.; Soler-Bistue, A.; Iriarte, A.; Tolmasky, M.; Bonomo, R. A.; Melano, R.; Ramirez, M. S.

10.1101/308833 — microbiology — Posted on 2018-04-26

260 A unified encyclopedia of human functional DNA elements through fully automated annotation of 164 human cell types

Libbrecht, M. W.; Rodriguez, O.; Weng, Z.; Hoffman, M.; Bilmes, J. A.; Noble, W. S.

10.1101/086025 — genomics — Posted on 2018-04-26

261 High Resolution Single Particle Cryo-Electron Microscopy using Beam-Image Shift

Cheng, A.; Eng, E. T.; Alink, L.; Rice, W. J.; Jordan, K. D.; Kim, L. Y.; Potter, C. S.; Carragher, B.

10.1101/306241 — biophysics — Posted on 2018-04-26

262 Visualizing single-cell RNA-seq datasets with Similarity Weighted Nonnegative Embedding

Wu, Y.; Tamayo, P.; Zhang, K.

10.1101/276261 — bioinformatics — Posted on 2018-04-26

263 Role of inhibitory control in modulating spread of focal ictal activity

Liou, J.-y.; Ma, H.; Wenzel, M.; Zhao, M.; Baird-Daniel, E.; Smith, E.; Daniel, A.; Emerson, R. G.; Yuste, R.; Schwartz, T. H.; Schevon, C.

10.1101/146407 — neuroscience — Posted on 2018-04-26

264 TMS orientation and pulse waveform manipulation activates different neural populations: direct evidence from TMS-EEG

Pisoni, A.; Vergallito, A.; Mattavelli, G.; Varoli, E.; Matteo, F.; Rosanova, M.; Casali, A. G.; Romero Lauro, L. J.

10.1101/308981 — neuroscience — Posted on 2018-04-26

265 Transcranial photoacoustic imaging of NMDA-evoked focal circuit dynamics in rat forebrain

Kang, J.; Kadam, S. D.; Elmore, J. S.; Sullivan, B. J.; Valentine, H.; Malla, A. P.; Grace, A. A.; Rahmim, A.; Loew, L. M.; Baumann, M.; Gjedde, A.; Boctor, E. M.; Wong, D. F.

10.1101/308585 — neuroscience — Posted on 2018-04-26

266 Transcriptome Analysis of Four Arabidopsis thaliana Mediator Tail Mutants Reveals Overlapping and Unique Functions in Gene Regulation

Dolan, W. L.; Chapple, C.

10.1101/309153 — genetics — Posted on 2018-04-26

267 Loter: A software package to infer local ancestry for a wide range of species

Dias-Alves, T.; Mairal, J.; Blum, M. G. B.

10.1101/213728 — bioinformatics — Posted on 2018-04-26

268 Probing the chemical-biological relationship space with the Drug Target Explorer

Allaway, R.; La Rosa, S.; Guinney, J.; Gosline, S. J.

10.1101/308700 — pharmacology and toxicology — Posted on 2018-04-26

269 Low-cost HPV testing and the prevalence of cervical infection in asymptomatic populations in Guatemala

Lou, H.; Gharzouzi, E.; Guerra, S. P.; Domgue, J. F.; Torres-Gonzalez, E.; Sawitzke, J.; Villagran, G.; Garland, L.; Boland, J.; Wagner, S.; Martinez, J.; Rosas, H.; Troxler, J.; McMillen, H.; Kessing, B.; Alvirez, E.; Castillo, M.; Morales, H.; Argueta, V.; Rosingh, A.; van Aerde-van Nunen, F. J. H. B.; Pinedo, H. M.; Lopez, G.; Pinedo, H. M.; Schiffman, M.; Dean, M.; Orozco, R.

10.1101/134775 — molecular biology — Posted on 2018-04-26

270 Rationally designed mimotope library for profiling of the human IgM repertoire

Pashov, A. D.; Shivarov, V.; Hadzhieva, M.; Kostov, V.; Ferdinandov, D.; Heinz, K.-M.; Pashova, S.; Todorova, M.; Vassilev, T. L.; Kieber-Emmons, T.; Meza-Zepeda, L. A.; Hovig, E.

10.1101/308973 — immunology — Posted on 2018-04-26

271 Oscillatory cortical forces promote three dimensional cell intercalations that shape the mandibular arch

Tao, H.; Zhu, M.; Lau, K.; Whitley, O.; Samani, M.; Xiao, X.; Chen, X. X.; Hahn, N. A.; Liu, W.; Valencia, M.; Wu, M.; Wang, X.; Fenelon, K. D.; Pasiliao, C. C.; Hu, D.; Wu, J.; Spring, S.; Ferguson, J.; Karuana, E. P.; Henkelman, R. M.; Dunn, A.; Huang, H.; Ho, H.-Y. H.; Atit, R.; Goyal, S.; Sun, Y.; Hopyan, S.

10.1101/309120 — developmental biology — Posted on 2018-04-26

272 Frequency shifts and depth dependence of premotor beta band activity during perceptual decision-making

Chandrasekaran, C.; Bray, I. E.; Shenoy, K. V.

10.1101/306753 — neuroscience — Posted on 2018-04-26

273 Oxytocin enhancement of emotional empathy: generalization across cultures and effects on amygdala activity

Geng, Y.; Zhao, W.; Zhou, F.; Ma, X.; Yao, S.; Hurlemann, R.; Becker, B.; Kendrick, K.

10.1101/307256 — neuroscience — Posted on 2018-04-26

274 Perceptual insensitivity to higher-order statistical moments of coherent random dot motion

Waskom, M. L.; Asfour, J. W.; Kiani, R.

10.1101/261370 — neuroscience — Posted on 2018-04-26

275 Symbiont switching and alternative resource acquisition strategies drive mutualism breakdown

Werner, G. D. A.; Cornelissen, J. H. C.; Cornwell, W. K.; Soudzilovskaia, N. A.; Kattge, J.; West, S. A.; Kiers, T.

10.1101/242834 — evolutionary biology — Posted on 2018-04-26

276 The miR-96 and RAR&gamma signaling axis governs androgen signaling and prostate cancer progression

Long, M. D.; Singh, P. K.; Russell, J. R.; Llimos, G.; Rosario, S.; Rizvi, A.; Withers, H.; van den Berg, P. R.; Kirk, J.; Sucheston-Campbell, L. E.; Smiraglia, D. J.; Campbell, M. J.

10.1101/198465 — cancer biology — Posted on 2018-04-26

277 Elevated alpha 1 antitrypsin is a major component of GlycA-associated risk for future morbidity and mortality

Ritchie, S. C.; Kettunen, J.; Brozynska, M.; Nath, A. P.; Havulinna, A. S.; Männisto, S.; Perola, M.; Salomaa, V.; Ala-Korpela, M.; Abraham, G.; Würtz, P.; Inouye, M.

10.1101/309138 — systems biology — Posted on 2018-04-26

278 2,4-Diaminothienopyrimidines, a new class of anthelmintic with activity against adult and egg stages of whipworm

Partridge, F. A.; Forman, R.; Willis, N. J.; Bataille, C. J.; Murphy, E. A.; Brown, A. E.; Heyer-Chauhan, N.; Marinic, B.; Sowood, D. J.; Wynne, G. M.; Else, K. J.; Russell, A. J.; Sattelle, D. B.

10.1101/254037 — pharmacology and toxicology — Posted on 2018-04-26

279 The identification of cortical pyramidal neurons using a RPP based algorithm

Kolezeva, Y.

10.1101/309088 — neuroscience — Posted on 2018-04-26

280 Interaction pathways promote spliceosome module integration and network-level robustness to cascading effects

Guimaraes, P. R.; Pires, M. M.; Cantor, M.; Coltri, P. P.

10.1101/302570 — molecular biology — Posted on 2018-04-26

281 Environmentally enriched pigs have transcriptional profiles consistent with neuroprotective effects and reduced microglial activity

Brown, S. M.; Bush, S. J.; Summers, K. M.; Hume, D. A.; Lawrence, A. B.

10.1101/262469 — molecular biology — Posted on 2018-04-26

282 Alopecia areata susceptibility variant identified by MHC risk haplotype sequencing reproduces symptomatic patched hair loss in mice

Oka, A.; Takagi, A.; Komiyama, E.; Mano, S.; Hosomichi, K.; Suzuki, S.; Motosugi, N.; Hatanaka, T.; Kimura, M.; Ueda, M. T.; Nakagawa, S.; Miura, H.; Ohtsuka, M.; Haida, Y.; Tanaka, M.; Komiyama, T.; Otomo, A.; Hadano, S.; Mabuchi, T.; Beck, S.; Inoko, H.; Ikeda, S.

10.1101/308197 — genomics — Posted on 2018-04-26

283 Influence of different modes of morphological character correlation on phylogenetic tree inference

Guillerme, T.; Brazeau, M. D.

10.1101/308742 — evolutionary biology — Posted on 2018-04-26

284 Prediction of the closed conformation and insights into the mechanism of the membrane enzyme LpxR

Saunders, G. M.; Bruce Macdonald, H. E.; Essex, J. W.; Khalid, S.

10.1101/309096 — biophysics — Posted on 2018-04-26

285 Extreme Amyloid Polymorphism in Staphylococcus aureus Virulent PSMα Peptides

Salinas, N.; Colletier, J.-P.; Moshe, A.; Landau, M.

10.1101/309062 — biochemistry — Posted on 2018-04-26

286 Cascaded Processing of Amplitude Modulation for Natural Sound Recognition

Koumura, T.; Terashima, H.; Furukawa, S.

10.1101/308999 — neuroscience — Posted on 2018-04-26

287 The universally-conserved transcription factor RfaH is recruited to a hairpin structure of the non-template DNA strand

Zuber, P. K.; Artsimovitch, I.; NandyMazumdar, M.; Liu, Z.; Nedialkov, Y.; Schweimer, K.; Roesch, P.; Knauer, S. H.

10.1101/264887 — biochemistry — Posted on 2018-04-26

288 Emergent sub-population behavior uncovered with a community dynamic metabolic model of Escherichia coli diauxic growth

Succurro, A.; Segre, D.; Ebenhöh, O.

10.1101/291492 — systems biology — Posted on 2018-04-26

289 Single Cell Transcriptomics of Pancreatic Cancer Precursors Demonstrates Epithelial and Microenvironmental Heterogeneity as an Early Event in Neoplastic Progression

Bernard, V.; Semaan, A.; Huang, J.; San Lucas, F. A.; Mulu, F. C.; Stephens, B. M.; Guerrero, P. A.; Huang, Y.; Zhao, J.; Kamyabi, N.; Sen, S.; Scheet, P. A.; Taniguchi, C. M.; Kim, M. P.; Tzeng, C.-W.; Katz, M. H.; Singhi, A. D.; Maitra, A.; Alvarez, H. A.

10.1101/306134 — pathology — Posted on 2018-04-26

290 Characterization of the apicomplexan amino acid transporter (ApiAT) family in Toxoplasma gondii

Parker, K. E. R.; Fairweather, S. J.; Rajendran, E.; Blume, M.; McConville, M. J.; Broer, S.; Kirk, K.; van Dooren, G.

10.1101/306993 — microbiology — Posted on 2018-04-26

291 Shifts in the gut microbiota structure caused by Helicobacter pylori eradication therapy

Olekhnovich, E. I.; Manolov, A. I.; Prianichniikov, N. A.; Samoilov, A. E.; Malakhova, M. V.; Pavlenko, A. V.; Babenko, V. V.; Larin, A. K.; Babin, Y. Y.; Starikova, E. V.; Chuvelev, D. I.; Kovarsky, B. A.; Tregubova, M. A.; Safina, D. D.; Markelova, M. I.; Grigoryeva, T. V.; Malanin, S. Y.; Abdulkhakov, R. A.; Abdulkhakov, S. R.; Kostryukova, E. S.; Ilina, E. N.; Govorun, V. M.

10.1101/296426 — genomics — Posted on 2018-04-26

292 Spontaneous emergence of self-replication in chemical reaction systems

Liu, Y.; Sumpter, D. J. T.

10.1101/278119 — biochemistry — Posted on 2018-04-26

293 Three new genome assemblies support a rapid radiation in Musa acuminata (wild banana)

Rouard, M.; Droc, G.; Martin, G.; Sardos, J.; Hueber, Y.; GUIGNON, V.; Cenci, A.; Geigle, B.; Hibbins, M. S.; Yahiaoui, N.; BAURENS, F.-C.; Berry, V.; Hahn, M. W.; D'Hont, A.; Roux, N.

10.1101/306605 — evolutionary biology — Posted on 2018-04-26

294 A protocol for an intercomparison of biodiversity and ecosystem services models using harmonized land-use and climate scenarios

Kim, H.; Rosa, I. M. D.; Alkemade, R.; Leadley, P.; Hurtt, G.; Popp, A.; van Vuuren, D.; Anthoni, P.; Arneth, A.; Baisero, D.; Caton, E.; Chaplin-Kramer, R.; Chini, L.; De Palma, A.; Di Fulvio, F.; Di Marco, M.; Espinoza, F.; Ferrier, S.; Fujimori, S.; Gonzalez, R. E.; Gueguen, M.; Guerra, C.; Hartfoot, M.; Harwood, T. D.; Hasegawa, T.; Haverd, V.; Havlik, P.; Hellweg, S.; Hill, S. L. L.; Hirata, A.; Hoskins, A. J.; Janse, J. H.; Jetz, W.; Johnson, J. A.; Krause, A.; Leclere, D.; Martins, I. S.; Matsui, T.; Merow, C.; Obersteiner, M.; Ohashi, H.; Poulter, B.; Purvis, A.; Quesada, B.; Rondinini

10.1101/300632 — ecology — Posted on 2018-04-26

295 Improved Analysis of Phage ImmunoPrecipitation Sequencing (PhIP-Seq) Data Using a Z-score Algorithm

Yuan, T.; Mohan, D.; Laserson, U.; Ruczinski, I.; Baer, A.; Larman, H. B.

10.1101/285916 — bioinformatics — Posted on 2018-04-26

296 NLMR and landscapetools: An integrated environment for simulating and modifying neutral landscape models in R

Sciaini, M.; Fritsch, M.; Scherer, C.; Simpkins, C. E.

10.1101/307306 — ecology — Posted on 2018-04-26

297 Shared Data Science Infrastructure for Genomics Data

Bagheri, H.; Muppirala, U.; Severin, A. J.; Rajan, H.

10.1101/307777 — bioinformatics — Posted on 2018-04-26

298 Whole genome amplification and sequencing of low cell numbers directly from a bacteria spiked blood model

Anscombe, C.; Misra, R. V.; Gharbia, S.

10.1101/153965 — microbiology — Posted on 2018-04-26

299 SPORTS1.0: a tool for annotating and profiling non-coding RNAs optimized for rRNA- and tRNA- derived small RNAs

Shi, J.; Ko, E.; Sanders, K. M.; Chen, Q.; Zhou, T.

10.1101/296970 — bioinformatics — Posted on 2018-04-26

300 Cortical control of kinematic primitives in mice performing a hold-still-center-out reach task

Bollu, T.; Whitehead, S. C.; Prasad, N.; Walker, J. R.; Shyamkumar, N.; Subramaniam, R.; Kardon, B. M.; Cohen, I.; Goldberg, J. H.

10.1101/304907 — neuroscience — Posted on 2018-04-26

301 Strength in numbers: collaborative science for new experimental model systems

Waller, R. F.; Cleves, P. A.; Rubio-Brotons, M.; Woods, A.; Bender, S. J.; Edgcomb, V.; Gann, E. R.; Jones, A. C.; Teytelman, L.; von Dassow, P.; Wilhelm, S. W.; Collier, J. L.

10.1101/308304 — microbiology — Posted on 2018-04-26

302 Estimation of genetic correlation using linkage disequilibrium score regression and genomic restricted maximum likelihood

Ni, G.; Moser, G.; Schizophrenia Working Group of the Psychiatric Gen, ; Wray, N. R.; Lee, S. H.

10.1101/194019 — genetics — Posted on 2018-04-26

303 Homeostatic plasticity scales dendritic spine volumes and changes the threshold and specificity of Hebbian plasticity

Hobbiss, A. F.; Ramiro Cortes, Y.; Israely, I.

10.1101/308965 — neuroscience — Posted on 2018-04-26

304 Regulation of transcription factor SP1 by β-catenin destruction complex modulates Wnt response

Mir, R.; Sharma, A.; Pradhan, S. J.; Galande, S.

10.1101/308841 — molecular biology — Posted on 2018-04-26

305 Distinctive types of postzygotic single-nucleotide mosaicisms in healthy individuals revealed by genome-wide profiling of multiple organs

Huang, Y.; Yang, X.; Wang, S.; Zheng, X.; Wu, Q.; Ye, Y.; Wei, L.

10.1101/309005 — genomics — Posted on 2018-04-26

306 The lipid droplet protein Pgc1 controls the subcellular distribution of phosphatidylglycerol

Kubalova, D.; Vesela, P.; Awadova, T.; Daum, G.; Malinsky, J.; Balazova, M.

10.1101/308874 — cell biology — Posted on 2018-04-26

307 A core transcriptional signature of human microglia: derivation and utility in describing region-dependent alterations associated with Alzheimer’s disease

Patir, A.; Shih, B.; McColl, B.; Freeman, T.

10.1101/308908 — neuroscience — Posted on 2018-04-26

308 Radially-patterned cell behaviours during tube budding from an epithelium

Sanchez-Corrales, Y. E.; Blanchard, G. B.; Roeper, K.

10.1101/308957 — developmental biology — Posted on 2018-04-26

309 Mitochondrial ubiquinone-mediated longevity is marked by reduced cytoplasmic protein translation

Molenaars, M.; Janssens, G. E.; Santermans, T.; Lezzerini, M.; Jelier, R.; MacInnes, A. W.; Houtkooper, R. H.

10.1101/308858 — systems biology — Posted on 2018-04-26

310 Interruption of signaling pathways in lung epithelial cell by Mycobacterium tuberculosis

Hadifar, S.; Behrouzi, A.; Fateh, A.; Khatami, S.; Rahimi Jamnani, F.; Siadat, S. D.; Vaziri, F.

10.1101/308882 — microbiology — Posted on 2018-04-26

311 Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors

Rousset, F.; Cui, L.; Siouve, E.; Depardieu, F.; Bikard, D.

10.1101/308916 — microbiology — Posted on 2018-04-26

312 Structural, functional and molecular dynamics analysis of cathepsin B gene SNPs associated with tropical calcific pancreatitis, a rare disease of tropics.

Singh, G.; MSK, J.; Sharma, R.; Bhat, B.; Madhusudhan, C.; Singh, A.

10.1101/308932 — bioinformatics — Posted on 2018-04-26

313 Defining of MAbs-neutralizing sites on the surface glycoproteins Gn and Gc of a hantavirus using vesicular stomatitis virus pseudotypes and site-directed mutagenesis

Levanov, L.; Iheozor-Ejiofor, R. P.; Lundkvist, A.; Vapalahti, O.; Plyusnin, A.

10.1101/307975 — microbiology — Posted on 2018-04-26

314 A mechanistic hydro-epidemiological model of liver fluke risk

Beltrame, L.; Dunne, T.; Rose Vineer, H.; Walker, J.; Morgan, E.; Vickerman, P.; McCann, C.; Williams, D.; Wagener, T.

10.1101/307348 — epidemiology — Posted on 2018-04-26

315 Geographic Latitude, Cholesterol, and Blood Pressure

Liu, Y.; Brook, R. D.; Liu, X.; Byrd, J. B.

10.1101/308726 — epidemiology — Posted on 2018-04-26

316 A synthetic bacterial information transfer system functions in the mammalian gut

Kim, S.; Kerns, S. J.; Ziesack, M.; Bry, L.; Gerber, G. K.; Way, J. C.; Silver, P. A.

10.1101/308734 — synthetic biology — Posted on 2018-04-26

317 Edge orientation perception during active touch

Olczak, D.; Sukumar, V.; Pruszynski, J. A.

10.1101/308759 — neuroscience — Posted on 2018-04-26

318 Evolution of the CLTCL1 Gene Encoding CHC22 Clathrin Reveals Selection Influencing CHC22’s Role in Human Glucose Metabolism

Fumagalli, M.; Diekmann, Y.; Camus, S. M.; Burke, A.; Camus, M. D.; Norman, P. J.; Joseph, A.-P.; Abi-Rached, L.; Benazzo, A.; Rasteiro, R.; Topf, M.; Parham, P.; Thomas, M. G.; Brodsky, F. M.

10.1101/307264 — genetics — Posted on 2018-04-26

319 MLL1 minimal catalytic complex is a dynamic conformational ensemble susceptible to pharmacological allosteric disruption

Kaustov, L.; Lemak, A.; Wu, H.; Faini, M.; Houliston, S.; Fan, L.; Fang, X.; Zeng, H.; Duan, S.; Allali-Hassani, A.; Vedadi, M.; Aebersold, R.; Wang, Y.; Arrowsmith, C. H.

10.1101/308676 — biophysics — Posted on 2018-04-26

320 Force-based three-dimensional model predicts mechanical drivers of cell sorting

Revell, C.; Blumenfeld, R.; Chalut, K.

10.1101/308718 — biophysics — Posted on 2018-04-26

321 KCH kinesin drives nuclear transport and cytoskeletal coalescence for tip cell growth

Yamada, M.; Goshima, G.

10.1101/308775 — cell biology — Posted on 2018-04-26

322 Human Cytomegalovirus Immediate-Early 1 Protein Causes Loss of SOX2 from Neural Progenitor Cells by Trapping Unphosphorylated STAT3 in the Nucleus

Wu, C.-C.; Jiang, X.; Wang, X.-Z.; Liu, X.-J.; Li, X.-J.; Yang, B.; Ye, H.-Q.; Harwardt, T.; Jiang, M.; Xia, H.-M.; Wang, W.; Britt, W. J.; Paulus, C.; Nevels, M.; Luo, M.-H.

10.1101/308171 — microbiology — Posted on 2018-04-25

323 FMRIPrep: a robust preprocessing pipeline for functional MRI

Esteban, O.; Markiewicz, C.; Blair, R. W.; Moodie, C.; Isik, A. I.; Erramuzpe Aliaga, A.; Kent, J.; Goncalves, M.; DuPre, E.; Snyder, M.; Oya, H.; Ghosh, S.; Wright, J.; Durnez, J.; Poldrack, R.; Gorgolewski, K. J.

10.1101/306951 — bioinformatics — Posted on 2018-04-25

324 Comparison of single gene and module-based methods for modeling gene regulatory networks

Hernaez, M.; Gevaert, O.

10.1101/307884 — systems biology — Posted on 2018-04-25

325 Sensorimotor cortical-subthalamic network dynamics during force generation

Alhourani, A.; Korzeniewska, A.; Wozny, T.; Lipski, W.; Kondylis, E.; Ghuman, A.; Crone, N.; Crammond, D.; Turner, R.; Richardson, R. M.

10.1101/306332 — neuroscience — Posted on 2018-04-25

326 Comparison between three concentration techniques for diagnosing intestinal parasites

Trabelsi, S.; Hanachi, M.; Cheikhrouhou, S.; Aloui, D.; Bouchekoua, M.; Khaled, S.

10.1101/308015 — microbiology — Posted on 2018-04-25

327 BgTEP: an antiprotease involved in innate immune sensing in Biomphalaria glabrata

Portet, A.; Galinier, R.; Pinaud, S.; Portela, J.; Nowacki, F.; Gourbal, B.; Duval, D.

10.1101/308130 — immunology — Posted on 2018-04-25

328 Local adaptation and maladaptation during the worldwide range expansion of a self-fertilizing plant

Cornille, A.; Salcedo, A.; Huang, H.; Kryvokhyzha, D.; Holm, K.; Ge, X. J.; Stinchcomb, J. R.; Glemin, S.; Wright, S.; Lascoux, M.

10.1101/308619 — evolutionary biology — Posted on 2018-04-25

329 TP53 Intron Derived Concentrations Implicate p53

Bermeister, K. G.; Dyne, J.; Yu, X.

10.1101/307959 — bioinformatics — Posted on 2018-04-25

330 Screening, Characterization and Optimization of antibacterial peptides, produced by Bacillus safensis strain MK-12 isolated from waste dump soil KP, Pakistan

Iqbal, S.; Qasim, M.; begum, F.; Rahman, H.; Sajid, I.

10.1101/308205 — microbiology — Posted on 2018-04-25

331 Enrichment of rare protein truncating variants in amyotrophic lateral sclerosis patients

Farhan, S. M. K.; Howrigan, D. P.; Abbott, L.; Byrnes, A.; Churchhouse, C.; Phatnani, H.; Smith, B.; Topp, S.; Rampersaud, E.; Wu, G.; Wuu, J.; Gubitz, A.; Kilm, J.; Mordes, D.; Ghosh, S.; CReATe Consortium, ; FALS Consortium, ; ALSGENS Consortium, ; Eggan, K.; Rademakers, R.; McCauley, J.; Schule, R.; Zuchner, S.; Benatar, M.; Taylor, J. P.; Nalls, M.; Traynor, B.; Shaw, C.; Goldstein, D.; Harms, M.; Daly, M.; Neale, B.

10.1101/307835 — genomics — Posted on 2018-04-25

332 Comment on \"Seasonal cycling in the gut microbiome of the Hadza hunter-gatherers of Tanzania\"

Schnorr, S. L.; Candela, M.; Rampelli, S.; Turroni, S.; Henry, A. G.; Crittenden, A. N.

10.1101/284513 — ecology — Posted on 2018-04-25

333 B7-H1(PD-L1) confers chemoresistance through ERK and p38 MAPK pathway in tumor cells

Wu, X.; Li, Y.; Liu, X.; Cao, S.; Harrington, S.; Chen, C.; Mansfield, A.; Dronca, R.; Park, S.; Yan, Y.; Kwon, E.; Wang, L.; Ling, K.; Dong, H.

10.1101/308601 — cancer biology — Posted on 2018-04-25

334 Quantitative photoacoustic imaging study of tumours in vivo

Martinho Costa, M.; Shah, A.; Rivens, I.; Box, C.; O'Shea, T.; Papaevangelou, E.; Bamber, J.; ter Haar, G.

10.1101/307595 — biophysics — Posted on 2018-04-25

335 Database-integrated genome screening (DIGS): exploring genomes heuristically using sequence similarity search tools and a relational database.

Zhu, H.; Dennis, T.; Hughes, J.; Gifford, R. J.

10.1101/246835 — bioinformatics — Posted on 2018-04-25

336 Sucrose or sucrose and caffeine differentially impact memory and anxiety like behaviours, and alter hippocampal parvalbumin and doublecortin

Xu, T. J.; Reichelt, A. C.

10.1101/308684 — neuroscience — Posted on 2018-04-25

337 ADAR2 mediated Q/R editing of GluK2 regulates homeostatic plasticity of kainate receptors

Gurung, S.; Evans, A. J.; Wilkinson, K. A.; Henley, J.

10.1101/308650 — neuroscience — Posted on 2018-04-25

338 Efficient cortical coding of 3D posture in freely behaving rats

Mimica, B.; Dunn, B. A.; Tombaz, T.; Bojja, V. P. T. N. C. S.; Whitlock, J. R.

10.1101/307785 — neuroscience — Posted on 2018-04-25

339 Bisulfite-free, Base-resolution, and Quantitative Sequencing of Cytosine Modifications

Liu, Y.; Siejka, P.; Velikova, G.; Yuan, F.; Tomkova, M.; Bai, C.; Chen, L.; Bi, Y.; Schuster-Boeckler, B.; Song, C.-X.

10.1101/307538 — genomics — Posted on 2018-04-25

340 NLMR and landscapetools: An integrated environment for simulating and modifying neutral landscape models in R

Sciaini, M.; Fritsch, M.; Scherer, C.; Simpkins, C. E.

10.1101/307306 — ecology — Posted on 2018-04-25

341 Meta-analysis of RNA-seq studies reveals genes responsible for life stage-dominant functions in Schistosoma mansoni

Lu, Z.; Berriman, M.

10.1101/308189 — developmental biology — Posted on 2018-04-25

342 Golgi stabilization, not its front-rear bias, is associated with EMT-enhanced fibrillar migration

Natividad, R. J.; Lalli, M. L.; Muthuswamy, S. K.; Asthagiri, A. R.

10.1101/308536 — cell biology — Posted on 2018-04-25

343 Identification of Key Proteins Associated with Myocardial Infarction using Bioinformatics and Systems Biology

Ahammad, I.

10.1101/308544 — bioinformatics — Posted on 2018-04-25

344 SPLASH: fast tandem mass spectra clustering using locality sensitive hashing

Wang, L.; Li, S.; Tang, H.

10.1101/308627 — bioinformatics — Posted on 2018-04-25

345 Shared Data Science Infrastructure for Genomics Data

Bagheri, H.; Muppirala, U.; Severin, A. J.; Rajan, H.

10.1101/307777 — bioinformatics — Posted on 2018-04-25

346 BPscore: an effective metric for meaningful comparisons of structural chromosome segmentations

Zaborowski, R.; Wilczynski, B.

10.1101/307330 — bioinformatics — Posted on 2018-04-25

347 Continuous Dice Coefficient: a Method for Evaluating Probabilistic Segmentations

Shamir, R. R.; Duchin, Y.; Kim, J.; Sapiro, G.; Harel, N.

10.1101/306977 — bioengineering — Posted on 2018-04-25

348 Mob-family kinase co-activators bind cognate Ndr/Lats kinases through conserved and modular interface

Parker, B.; Gogl, G.; Balint, M.; Hetenyi, C.; Remenyi, A.; Weiss, E.

10.1101/242115 — biochemistry — Posted on 2018-04-25

349 Genotyping by sequencing of 393 Sorghum bicolor BTx623 x IS3620C recombinant inbred lines improves sensitivity and resolution of QTL detection

Kong, W.; Kim, C.; Zhang, D.; Guo, H.; Tan, X.; Jin, H.; Zhou, C.; Shuang, L.-s.; Goff, V.; Sezen, U. U.; Pierce, G.; Compton, R.; Lemke, C.; Robertson, J.; Rainville, L.; Auckland, S.; Paterson, A. H.

10.1101/308478 — genetics — Posted on 2018-04-25

350 The three regimes of spatial recovery

Zelnik, Y. R.; Arnoldi, J.-F.; Loreau, M.

10.1101/308635 — ecology — Posted on 2018-04-25

351 Correlations, interactions, and predictability in virus-microbe communities

Coenen, A. R.; Weitz, J. S.

10.1101/176628 — ecology — Posted on 2018-04-25

352 Dissecting the control mechanisms for DNA replication and cell division in E. coli

Micali, G.; Grilli, J.; Marchi, J.; Osella, M.; Cosentino Lagomarsino, M.

10.1101/308155 — cell biology — Posted on 2018-04-25

353 Cell-cell contact dictates life or death decisions following CD95 activation in cancer

Gulculer Balta, G. S.; Monzel, C.; Kleber, S.; Beaudouin, J.; Kaindl, T.; Thiemann, M.; Wirtz, C. R.; Tanaka, M.; Martin-Villalba, A.

10.1101/308346 — cancer biology — Posted on 2018-04-25

354 Differential alteration of IL-8 in liver cancer stem cell enrichment in response to PI3K/Akt/mTOR inhibitors and sorafenib

Kahraman, D. C.; Kahraman, T.; Cetin-Atalay, R.

10.1101/306910 — cancer biology — Posted on 2018-04-25

355 Movement-related activity dominates cortex during sensory-guided decision making

Musall, S.; Kaufman, M. T.; Gluf, S.; Churchland, A.

10.1101/308288 — neuroscience — Posted on 2018-04-25

356 Detection of viral pathogens with multiplex Nanopore MinION sequencing: be careful with cross-talk

Xu, Y.; Lewandowski, K.; Lumley, S.; Pullan, S.; Vipond, R.; Carroll, M.; Foster, D.; Matthews, P.; Peto, T.; Crook, D.

10.1101/308262 — bioinformatics — Posted on 2018-04-25

357 Isonitrile Formation by a Non-heme Iron(II)-dependent Oxidase/Decarboxylase

Harris, N. C.; Born, D. A.; Cai, W.; Huang, Y.; Martin, J.; Khalaf, R.; Drennan, C. L.; Zhang, W.

10.1101/308460 — biochemistry — Posted on 2018-04-25

358 Long-term community change through multiple rapid transitions in a desert rodent community

Christensen, E.; Harris, D.; Ernest, M.

10.1101/163931 — ecology — Posted on 2018-04-25

359 Discovery of Large Disjoint Motif in Biological Network using Dynamic Expansion Tree

Patra, S.; Mohapatra, A.

10.1101/308254 — bioinformatics — Posted on 2018-04-25

360 Reverse Engineered Virtual Patient Populations as Surrogates for Real Patient-Level Data

Alenghat, F. J.

10.1101/308403 — bioinformatics — Posted on 2018-04-25

361 The effect of symbiosis between silkworm (Bombyx mori) and Firmicutes on silk production

Medina, K.

10.1101/308429 — zoology — Posted on 2018-04-25

362 Quantifying multi-layered expression regulation in response to stress of the endoplasmic reticulum

Rendleman, J.; Cheng, Z.; Maity, S.; Kastelic, N.; Munschauer, M.; Allgoewer, K.; Teo, G.; Zhang, Y. B.; Lei, A.; Parker, B.; Landthaler, M.; Freeberg, L.; Kuersten, S.; Choi, H.; Vogel, C.

10.1101/308379 — systems biology — Posted on 2018-04-25

363 iPSC-derived neurons as a tool for probing molecular pharmacology of antipsychotic action.

Kim, E. S.; Leonardo, E. D.; Dranovsky, A.

10.1101/308486 — pharmacology and toxicology — Posted on 2018-04-25

364 Endothelin receptor Aa regulates proliferation and differentiation of Erb-dependant pigment progenitors in zebrafish

Camargo Sosa, K.; Colanesi, S.; Muller, J.; Schulte-Merker, S.; Stemple, D.; Patton, E. E.; Kelsh, R. N.

10.1101/308221 — developmental biology — Posted on 2018-04-25

365 Quantification of biases in predictions of protein stability changes upon mutations

Pucci, F.; Bernaerts, K.; Kwasigroch, J. M.; Rooman, M.

10.1101/308239 — bioinformatics — Posted on 2018-04-25

366 Ablation of proliferating neural stem cells during early life is sufficient to reduce adult hippocampal neurogenesis

Youssef, M.; Krish, V. S.; Kirshenbaum, G. S.; Atsak, P.; Lass, T. J.; Lieberman, S. R.; Leonardo, E. D.; Dranovsky, A.

10.1101/308387 — neuroscience — Posted on 2018-04-25

367 Cycloserine for Treatment of Multidrug-Resistant Tuberculosis in China: A Retrospective Observational Study

Li, Y.; Wang, F.; Wu, L.; ZHU, M.; He, G.; Sun, F.; Liu, Q.; Wang, X.; Zhang, W.

10.1101/307124 — microbiology — Posted on 2018-04-25

368 A web portal for gene expression across all life stages of Schistosoma mansoni

Lu, Z.; Zhang, Y.; Berriman, M.

10.1101/308213 — bioinformatics — Posted on 2018-04-25

369 A retrieved context model of the emotional modulation of memory

Talmi, D.; Lohnas, L.; Daw, N.

10.1101/175653 — neuroscience — Posted on 2018-04-25

370 The HCP 7T Retinotopy Dataset

Benson, N.; Jamison, K. W.; Arcaro, M. J.; Vu, A.; Glasser, M. F.; Coalson, T. S.; Van Essen, D.; Yacoub, E.; Ugurbil, K.; Winawer, J.; Kay, K.

10.1101/308247 — neuroscience — Posted on 2018-04-25

371 Short loop motif profiling of protein interaction networks in acute myeloid leukaemia

Chung, S. S.; Laddach, A.; Thomas, N. S. B.; Fraternali, F.

10.1101/306886 — bioinformatics — Posted on 2018-04-25

372 Optimisation of a novel method for the production of single-span membrane proteins in Escherichia coli

Smith, S. M.; Walker, K. L.; Smith, C. J.; Robinson, C.

10.1101/308445 — biochemistry — Posted on 2018-04-25

373 Standing Sentinel during Human Sleep: Continued Evaluation of Environmental Stimuli in the Absence of Consciousness

Blume, C.; del Giudice, R.; Wislowska, M.; Heib, D. P. J.; Schabus, M.

10.1101/187195 — neuroscience — Posted on 2018-04-25

374 Complete plastome sequence from Bertholletia excelsa and 23 related species yield informative markers for Lecythidaceae

Thomson, A. M.; Vargas, O. M.; Dick, C. W.

10.1101/192112 — evolutionary biology — Posted on 2018-04-25

375 ARKS: chromosome-scale scaffolding of human genomedrafts with linked read kmers

Coombe, L.; Zhang, J.; Vandervalk, B. P.; Chu, J.; Jackman, S. D.; Birol, I.; Warren, R. L.

10.1101/306902 — bioinformatics — Posted on 2018-04-25

376 PiFlow: A Biocompatible Low-Cost Programmable Dynamic Flow Pumping System Utilizing a Raspberry Pi Zero and Commercial Piezoelectric Pumps

Kassis, T.; Perez, P. M.; Yang, C. J. W.; Soenksen, L. R.; Trumper, D. L.; Griffith, L. G.

10.1101/192047 — bioengineering — Posted on 2018-04-25

377 The Italian Autism Network (ITAN): A Resource for Molecular Genetics and Biomarker Investigations

Muglia, P.; Filosi, M.; Da Ros, L.; Kam-Thong, T.; Nardocci, F.; Trabetti, E.; Ratti, E.; Rizzini, P.; Zuddas, A.; Dalla Bernardina, B.; Domenici, E.; The Italian Autism Network (ITAN),

10.1101/306845 — neuroscience — Posted on 2018-04-25

378 Association Between Colonic Level of microRNA 31 and Subtypes of Adult and Pediatric Crohn’s Disease

Keith, B. P.; Barrow, J. B.; Kazgan, N.; Shah, N. D.; Gipson, G. R.; Pitman, W. A.; Saxena, S. J.; Wolber, E. A.; Schaner, M. S.; Hoffner O'Connor, M.; Tradd, O. K.; Kanke, M.; Toyonaga, T.; Chaumont, N.; Sadiq, T. S.; Koruda, M. J.; Cotney, P. A.; Allbritton, N.; Trembath, D. G.; Sylvester, F.; Furey, T. S.; Sethupathy, P.; Sheikh, S. Z.

10.1101/307561 — genomics — Posted on 2018-04-25

379 Seeing spots: Quantifying mother-offspring similarity and assessing fitness consequences of coat pattern traits in a wild population of giraffes (Giraffa camelopardalis)

Lee, D. E.; Cavener, D. R.; Bond, M. L.

10.1101/161281 — evolutionary biology — Posted on 2018-04-25

380 Learning naturalistic temporal structure in the posterior medial network

Aly, M.; Chen, J.; Turk-Browne, N. B.; Hasson, U.

10.1101/196287 — neuroscience — Posted on 2018-04-25

381 In vivo characterization and quantification of neurofibrillary tau PET radioligand 18F-MK-6240 in humans from Alzheimer’s disease dementia to young controls

Betthauser, T. J.; Cody, K. A.; Zammit, M. D.; Murali, D.; Converse, A. K.; Barnhart, T. E.; Stone, C. K.; Rowley, H. A.; Johnson, S. C.; Christian, B. T.

10.1101/290064 — neuroscience — Posted on 2018-04-25

382 Transgenerational sterility of Piwi pathway mutants in response to germ granule dysfunction

Kretovich Billmyre, K.; Heestand, B.; Spichal, M.; Frenk, S.; Ahmed, S.

10.1101/276782 — developmental biology — Posted on 2018-04-25

383 Including phenotypic causal networks in genome-wide association studies using mixed effects structural equation models

Momen, M.; Mehrgardi, A. A.; Roudbar, M. A.; Kranis, A.; Pinto, R. M.; Valente, B. D.; Morota, G.; Rosa, G. J.; Gianola, D.

10.1101/251421 — genetics — Posted on 2018-04-25

384 Visualizing Wnt secretion from endoplasmic reticulum to filopodia

Moti, N.; Yu, J.; Boncompain, G.; Perez, F.; Virshup, D. M.

10.1101/271684 — cell biology — Posted on 2018-04-25

385 Physical and functional cell-matrix uncoupling in a developing tissue under tension

Proag, A.; Monier, B.; Suzanne, M.

10.1101/306696 — cell biology — Posted on 2018-04-25

386 Signal-to-Noise ratio made easy: A tool to assess your confocal performance

Ferrand, A.; Schleicher, K. D.; Ehrenfeuchter, N.; Heusermann, W.; Biehlmaier, O.

10.1101/291500 — biophysics — Posted on 2018-04-25

387 Bidirectional control of orienting behavior by distinct prefrontal circuits

Huda, R.; Sipe, G. O.; Adam, E.; Breton-Provencher, V.; Pho, G.; Gunter, L.; Wickersham, I. R.; Sur, M.

10.1101/307009 — neuroscience — Posted on 2018-04-25

388 Novel features in the structure of P-glycoprotein (ABCB1) in the post-hydrolytic state as determined at 7.9A resolution

Thongin, N.; Collins, R. F.; Barbieri, A.; Shafi, T.; Siebert, A.; Ford, R. C.

10.1101/308114 — biochemistry — Posted on 2018-04-25

389 Identification of a novel subfamily of bacterial AAT-fold basic amino acid decarboxylases and functional characterization of its first representative: Pseudomonas aeruginosa LdcA

Carriel-Lopez, D.; Garcia, P. S.; Castelli, F.; Lamourette, P.; Fenaille, F.; Brochier-Armanet, C.; Elsen, S.; Gutsche, I.

10.1101/308080 — microbiology — Posted on 2018-04-25

390 Imaging beyond the super-resolution limits using ultrastructure expansion microscopy (UltraExM)

Gambarotto, D.; Zwettler, F.; Cernohorska, M.; Fortun, D.; Borgers, S.; Heine, J.; Schloetel, J.-G.; Reuss, M.; Unser, M.; Boyden, E.; Sauer, M.; Hamel, V.; Guichard, P.

10.1101/308270 — cell biology — Posted on 2018-04-25

391 Colistin heteroresistance and the involvement of the PmrAB regulatory system in Acinetobacter baumannii

Charretier, Y.; Diene, S. M.; Baud, D.; Chatellier, S.; Santiago-Allexant, E.; van Belkum, A.; Guigon, G.; Schrenzel, J.

10.1101/307132 — microbiology — Posted on 2018-04-25

392 Host identity and functional traits determine the community composition of the arbuscular mycorrhizal fungi in facultative epiphytic plant species

Alguacil, M. d. M.; Diaz, G.; Torres, M. P.; Rodriguez-Caballero, G.; Roldan, A.

10.1101/307991 — microbiology — Posted on 2018-04-25

393 The Integrative Conjugative Element (ICE) of Mycoplasma agalactiae: key elements involved in horizontal dissemination and influence of co-resident ICEs

Baranowski, E.; Dordet-Frisoni, E.; Sagne, E.; Hygonenq, M.-C.; Pretre, G.; Claverol, S.; Fernandez, L.; Nouvel, L.-X.; Citti, C.

10.1101/308072 — microbiology — Posted on 2018-04-25

394 A generic normalization method for proper quantification in untargeted proteomics screening

Anjo, S. I.; Simoes, I.; Castanheira, P.; Graos, M.; Manadas, B.

10.1101/307504 — biochemistry — Posted on 2018-04-25

395 Multi-target visual search organisation across the lifespan: Cancellation task performance in a large and demographically stratified sample of healthy adults

Benjamins, J. S.; Dalmaijer, E. S.; Ten Brink, A. F.; Nijboer, T. C. W.; Van der Stigchel, S.

10.1101/307520 — neuroscience — Posted on 2018-04-25

396 Machine learning based prediction of functional capabilities in metagenomically assembled microbial genomes

Farrell, F.; Soyer, O. S.; Quince, C.

10.1101/307157 — microbiology — Posted on 2018-04-25

397 Cis- and trans-acting factors influence expression of the norM-encoded efflux pump of Neisseria gonorrhoeae and levels of gonococcal susceptibility to substrate antimicrobials

Rouquette-Loughlin, C.; Dhulipala, V.; Reimche, J. L.; Raterman, E.; Begum, A.; Jerse, A. E.; Shafer, W. M.

10.1101/308031 — microbiology — Posted on 2018-04-25

398 Kinome expansion in the Fusarium oxysporum species complex driven by accessary chromosomes

DeIuilo, G. A.; Guo, L.; Zhang, Y.; Goldberg, J.; Kistler, C.; Ma, L.-J.

10.1101/308064 — genomics — Posted on 2018-04-25

399 Host sexual dimorphism affects the outcome of within-host pathogen competition

Gipson, S. A. Y.; Jimenez, L.; Hall, M.

10.1101/306985 — evolutionary biology — Posted on 2018-04-25

400 SHP2 Inhibition Abrogates MEK inhibitor Resistance in Multiple Cancer Models

Fedele, C.; Ran, H.; Diskin, B.; Wei, W.; Jen, J.; Araki, K.; Simeone, D. M.; Miller, G.; Neel, B. G.; Tang, K. H.

10.1101/307876 — cancer biology — Posted on 2018-04-25

401 Benchmarking tree and ancestral sequence inference for B cell receptor sequences

Davidsen, K.; Matsen, F.

10.1101/307736 — immunology — Posted on 2018-04-25

402 TSA-Seq Mapping of Nuclear Genome Organization

Chen, Y.; Zhang, Y.; Wang, Y.; Zhang, L.; Brinkman, E. K.; Adam, S. A.; Goldman, R.; van Steensel, B.; Ma, J.; Belmont, A. S.

10.1101/307892 — genomics — Posted on 2018-04-25

403 Evidence of a nonadaptive buildup of mutational load in human populations over the past 40,000 years

Aris-Brosou, S.

10.1101/307058 — evolutionary biology — Posted on 2018-04-25

404 When higher carrying capacities lead to faster propagation

Haond, M.; Morel-Journel, T.; Lombaert, E.; Vercken, E.; Mailleret, L.; Roques, L.

10.1101/307322 — ecology — Posted on 2018-04-25

405 BioVR: a platform for virtual reality assisted biological data integration and visualization

Zhang, J. F.; Paciorkowski, A. R.; Craig, P. A.; Cui, F.

10.1101/307769 — bioinformatics — Posted on 2018-04-25

406 Microstructural integrity of white matter moderates an association between childhood adversity and adult trait anger

Kim, M. J.; Elliott, M. L.; d'Arbeloff, T. C.; Knodt, A. R.; Radtke, S. R.; Brigidi, B. D.; Hariri, A. R.

10.1101/307637 — neuroscience — Posted on 2018-04-25

407 Characterization of genomic DNA of lactic acid bacteria for activation of plasmacytoid dendritic cells .

Horie, A.; Tomita, Y.; Oshio, K.; Fujiwara, D.; Fujii, T.

10.1101/307074 — microbiology — Posted on 2018-04-25

408 Antimicrobial susceptibility patterns of anaerobic bacteria in Victoria, Australia.

Teng, J. C.; Dreyer, L.

10.1101/308023 — microbiology — Posted on 2018-04-25

409 The Genome of BAM-degrading Aminobacter sp. MSH1 with Several Low Copy Plasmids

Nielsen, T. K.; Hylling, O.; Ellegaard-Jensen, L.; Aamand, J.; Hansen, L. H.

10.1101/307967 — microbiology — Posted on 2018-04-25

410 Pressure sensitivity of ANME-3 predominant anaerobic methane oxidizing community from coastal marine Lake Grevelingen sediment

Cassarini, C.; Zhang, Y.; Lens, P. N. L.

10.1101/307082 — microbiology — Posted on 2018-04-25

411 Leucocyte integrins but not caspases or NLR inflammasome are associated with lipopolysaccharide recognition and response in barramundi (Lates calcarifer)

Zoccola, E. C.; Kellie, S.; Barnes, A. C.

10.1101/307017 — immunology — Posted on 2018-04-25

412 Permanent neuroglial remodeling of the retina following infiltration of CSF1R-inhibition resistant peripheral monocytes.

Paschalis, E. I.; Lei, F.; Zhou, C.; Kapoulea, V.; Dana, R.; Chodosh, J.; Vavvas, D. G.; Dohlman, C. H.

10.1101/307900 — immunology — Posted on 2018-04-25

413 Genome-wide analysis of cell cycle-regulating genes in the symbiotic dinoflagellate Symbiodinium minutum.

Cato, M. L.; Jester, H. D.; Lavertu, A.; Lyman, A.; Tallent, L. M.; Mitchell, G.

10.1101/307546 — genomics — Posted on 2018-04-25

414 The genome of Ectocarpus subulatus highlights unique mechanisms for stress tolerance in brown algae

Dittami, S. M.; Corre, E.; Brillet-Gueguen, L.; Pontoizeau, N.; Aite, M.; Avia, K.; Caron, C.; Cho, C. H.; Collen, J.; Cormier, A.; Delage, L.; Doubleau, S.; Frioux, C.; Gobet, A.; Gonzalez-Navarrete, I.; Groisillier, A.; Herve, C.; Jollivet, D.; KleinJan, H.; Leblanc, C.; Lipinska, A. P.; Liu, X.; Marie, D.; Markov, G. V.; Minoche, A. E.; Monsoor, M.; Pericard, P.; Perrineau, M.-M.; Peters, A. F.; Siegel, A.; Simeon, A.; Trottier, C.; Yoon, H. S.; Himmelbauer, H.; Boyen, C.; Tonon, T.

10.1101/307165 — genomics — Posted on 2018-04-25

415 EquCab3, an Updated Reference Genome for the Domestic Horse

Kalbfleisch, T. S.; Rice, E.; DePriest, M. S.; Walenz, B. P.; Hestand, M. S.; Vermeesch, J. R.; O'Connell, B. L.; Fiddes, I. T.; Vershinina, A. O.; Petersen, J. L.; Finno, C. J.; Bellone, R. R.; McCue, M. E.; Brooks, S. A.; Bailey, E.; Orlando, L.; Green, R. E.; Miller, D. C.; Antczak, D. F.; MacLeod, J. N.

10.1101/306928 — genomics — Posted on 2018-04-25

416 Mutation-rate plasticity and the germline of unicells

Aanen, D.; Debets, A. J. M.

10.1101/307371 — evolutionary biology — Posted on 2018-04-25

417 Patterning of a telencephalon-like region in the adult brain of amphioxus

Benito Gutierrez, E.; Stemmer, M.; Rohr, S. D.; Schumacher, L. N.; Tang, J.; Marconi, A.; Jekely, G.; Arendt, D.

10.1101/307629 — evolutionary biology — Posted on 2018-04-25

418 Functional Balance between TCF21-Slug defines phenotypic plasticity and sub-classes in high-grade serous ovarian cancer

Varankar, S. S.; Kamble, S. C.; Mali, A. M.; More, M.; Abraham, A.; Kumar, B.; Pansare, K. J.; Narayanan, N. J.; Sen, A.; Dhake, R. D.; Joshi, A. N.; Midha, D.; Jolly, M. K.; Dong, Y.; Clements, J. A.; Bapat, S. A.

10.1101/307934 — cancer biology — Posted on 2018-04-25

419 Novel anionic cecropins from the spruce budworm feature a poly-L-aspartic acid C-terminus

maaroufi, H.; Cusson, M.; Levesque, R. C.

10.1101/307702 — bioinformatics — Posted on 2018-04-25

420 Computational Disease Subtyping based on Joint Analysis of Clinical and Genomic Data

Diaz, D.; Kotov, A.; Bollig-Fischer, A.

10.1101/307751 — bioinformatics — Posted on 2018-04-25

421 Co-evolution networks of HIV/HCV are modular with direct association to structure and function

Quadeer, A. A.; Morales-Jimenez, D.; McKay, M. R.

10.1101/307033 — bioinformatics — Posted on 2018-04-25

422 Ethane-dependent synthesis of polyhydroxyalkanoates by the obligate methanotroph Methylocystis parvus OBBP

Myung, J.; Flanagan, J. C.; Galega, W. M.; Waymouth, R. M.; Criddle, C. S.

10.1101/307108 — microbiology — Posted on 2018-04-25

423 ERM proteins: The missing actin linkers in clathrin-mediated endocytosis

Kvalvaag, A. S.; Schink, K. O.; Brech, A.; Sandvig, K.; Pust, S.

10.1101/307272 — cell biology — Posted on 2018-04-25

424 HaploJuice : Accurate haplotype assembly from a pool of sequences with known relative concentrations

Wong, T. K. F.; Ranjard, L.; Lin, Y.; Rodrigo, A. G.

10.1101/307025 — bioinformatics — Posted on 2018-04-25

425 HIV Peptidome-Wide Association Study Reveals Patient-Specific Epitope Repertoires Associated with HIV Control

Arora, J.; McLaren, P.; Chaturvedi, N.; Carrington, M.; Fellay, J.; Lenz, T. L.

10.1101/307314 — genomics — Posted on 2018-04-24

426 Effective population sizes and adaptive genetic variation in a captive bird population

Athrey, G.; Faust, N.; Hieke, A.-S. C.; Brisbin, I. L.

10.1101/307728 — genetics — Posted on 2018-04-24

427 EnTAP: Bringing Faster and Smarter Functional Annotation to Non-Model Eukaryotic Transcriptomes

Hart, A. J.; Ginzburg, S.; Xu, M.; Fisher, C. R.; Rahmatpour, N.; Mitton, J. B.; Paul, R.; Wegrzyn, J. L.

10.1101/307868 — bioinformatics — Posted on 2018-04-24

428 Longitudinal tracking of Plasmodium falciparum clones in complex infections by amplicon deep sequencing

Lerch, A.; Koepfli, C.; Hofmann, N. E.; Kattenberg, J. H.; Rosanas-Urgell, A.; Betuela, I.; Mueller, M.; Felger, I.

10.1101/306860 — microbiology — Posted on 2018-04-24

429 Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV

Dingens, A. S.; Acharya, P.; Haddox, H. K.; Rawi, R.; Xu, K.; Chuang, G.-Y.; Wei, H.; Mascola, J. R.; Carragher, B.; Potter, C. S.; Overbaugh, J.; Kwong, P. D.; Bloom, J. D.

10.1101/307587 — immunology — Posted on 2018-04-24

430 Gene regulatory mechanisms underlying the evolutionary loss of a polygenic trait

Lammers, M.; Kraaijeveld, K.; Mariën, J.; Ellers, J.

10.1101/307389 — evolutionary biology — Posted on 2018-04-24

431 rawDiag - an R package supporting rational LC-MS method optimization for bottom-up proteomics

Trachsel, C.; Panse, C.; Kockmann, T.; Wolski, W. E.; Grossmann, J.; Schlapbach, R.

10.1101/304485 — bioinformatics — Posted on 2018-04-24

432 Expanding the size limit of RNA viruses: Evidence of a novel divergent nidovirus in California sea hare, with a ~35.9 kb virus genome

Debat, H. J.

10.1101/307678 — microbiology — Posted on 2018-04-24

433 Association Between Colonic Level of microRNA 31 and Subtypes of Adult and Pediatric Crohn’s Disease

Sheikh, S. Z.; Keith, B. P.; Barrow, J. B.; Kazgan, N.; Shah, N. D.; Gipson, G. R.; Pitman, W. A.; Saxena, S. J.; Wolber, E. A.; Schaner, M. S.; Hoffner O'Connor, M.; Tradd, O. K.; Kanke, M.; Toyonaga, T.; Chaumont, N.; Sadiq, T. S.; Koruda, M. J.; Cotney, P. A.; Allbritton, N.; Trembath, D. G.; Sylvester, F.; Furey, T. S.; Sethupathy, P.

10.1101/307561 — genomics — Posted on 2018-04-24

434 GOcats: A tool for categorizing Gene Ontology into subgraphs of user-defined concepts

Hinderer, E. W.; Flight, R. M.; Moseley, H. N. B.

10.1101/306936 — systems biology — Posted on 2018-04-24

435 Elementary sensory-motor transformations underlying olfactory navigation in walking fruit-flies

Alvarez-Salvado, E.; Licata, A.; Connor, E. G.; McHugh, M. K.; King, B. M. N.; Stavropoulos, N.; Crimaldi, J. P.; Nagel, K. I.

10.1101/307660 — neuroscience — Posted on 2018-04-24

436 Pseudomonas aeruginosa Can Inhibit Growth of Streptococcal Species via Iron Sequestration

Scott, J.; Filkins, L.; Schwartzman, J.; O'Toole, G.

10.1101/307488 — microbiology — Posted on 2018-04-24

437 Single-cell chromatin interactions reveal regulatory hubs in dynamic compartmentalized domains

Oudelaar, A. M.; Davies, J. O. J.; Hanssen, L. L. P.; Telenius, J. M.; Schwessinger, R.; Liu, Y.; Brown, J. M.; Downes, D. J.; Chiariello, A. M.; Bianco, S.; Nicodemi, M.; Buckle, V. J.; Dekker, J.; Higgs, D. R.; Hughes, J. R.

10.1101/307405 — genetics — Posted on 2018-04-24

438 Filamin-A susceptibility to calpain-mediated cleavage as a marker of dynamic conformational changes in intact platelets

Buitrago, L.; Coller, B. S.

10.1101/307397 — biochemistry — Posted on 2018-04-24

439 Limb- and tendon-specific Adamtsl2 deletion identifies a soft tissue mechanism modulating bone length

Hubmacher, D.; Thacker, S.; Adams, S. M.; Birk, D.; Schweitzer, R.; Apte, S.

10.1101/307496 — developmental biology — Posted on 2018-04-24

440 Temperature explains broad patterns of Ross River virus transmission

Shocket, M. S.; Ryan, S. J.; Mordecai, E. A.

10.1101/286724 — ecology — Posted on 2018-04-24

441 Trait paranoia shapes inter-subject synchrony in brain activity during an ambiguous social narrative

Finn, E. S.; Corlett, P. R.; Chen, G.; Bandettini, P. A.; Constable, R. T.

10.1101/231738 — neuroscience — Posted on 2018-04-24

442 Efficiently controlling for case-control imbalance and sample relatedness in large-scale genetic association studies

Zhou, W.; Nielsen, J. B.; Fritsche, L. G.; Dey, R.; Elvestad, M. B.; Wolford, B. N.; LeFaive, J.; VandeHaar, P.; Gagliano, S. A.; Gifford, A.; Bastarache, L. A.; Wei, W.-Q.; Denny, J. C.; Lin, M.; Hveem, K.; Kang, H. M.; Abecasis, G. R.; Willer, C. J.; Lee, S.

10.1101/212357 — genomics — Posted on 2018-04-24

443 Stable between-subject statistical inference from unstable within-subject functional connectivity estimates

Vidaurre, D.; Woolrich, M. W.; Winkler, A. M.; Karapanagiotidis, T.; Smallwood, J.; Nichols, T. E.

10.1101/268151 — neuroscience — Posted on 2018-04-24

444 Open source tools for temporally controlled rodent behavior suitable for electrophysiology and optogenetic manipulations

Solari, N.; Sviatko, K.; Laszlovszky, T.; Hegedus, P.; Hangya, B.

10.1101/243469 — neuroscience — Posted on 2018-04-24

445 Ribosome provisioning activates a bistable switch coupled to fast exit from stationary phase

Remigi, P.; Ferguson, G. C.; De Monte, S.; Rainey, P. B.

10.1101/244129 — microbiology — Posted on 2018-04-24

446 Dissociable roles for the rTPJ and dmPFC in self-other processing: a HD-tDCS study

Martin, A. K.; Huang, J.; Meinzer, M.

10.1101/306183 — neuroscience — Posted on 2018-04-24

447 Expanded view of the ecological genomics of ant responses to climate change

Lau, M.; Ellison, A. M.; Nguyen, A. D.; Penick, C.; DeMarco, B.; Gotelli, N. J.; Sanders, N.; Dunn, R.; Helms Cahan, S.

10.1101/302679 — genomics — Posted on 2018-04-24

448 Bacillus safensis FO-36b and Bacillus pumilus SAFR-032: A Whole Genome Comparison of Two Spacecraft Assembly Facility Isolates

Tirumalai, M.; Stepanov, V. G.; Wunsche, A.; Montazari, S.; Gonzalez, R. O.; Venkateswaran, K.; Fox, G. E.

10.1101/283937 — genomics — Posted on 2018-04-24

449 Assessing the performance of real-time epidemic forecasts: A case study of the 2013-16 Ebola epidemic

Funk, S.; Camacho, A.; Kucharski, A. J.; Lowe, R.; Eggo, R. M.; Edmunds, W. J.

10.1101/177451 — epidemiology — Posted on 2018-04-24

450 Detecting and correcting for bias in Mendelian randomization analyses using gene-by-environment interactions

Spiller, W.; Slichter, D.; Bowden, J.; Davey Smith, G.

10.1101/187849 — epidemiology — Posted on 2018-04-24

451 The relative fitness of drug resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru

Knight, G. M.; Zimic, M.; Funk, S.; Gilman, R. H.; Friedland, J. S.; Grandjean, L.

10.1101/195313 — epidemiology — Posted on 2018-04-24

452 FENNEC - Functional Exploration of Natural Networks and Ecological Communities

Ankenbrand, M. J.; Hohlfeld, S. C. Y.; Weber, L.; Foerster, F.; Keller, A.

10.1101/194308 — ecology — Posted on 2018-04-24

453 A statistical framework for the robust detection of hidden variation in single cell transcriptomes

Lee, D.; Cheng, A.; Bolisetty, M.; Ucar, D.

10.1101/151217 — bioinformatics — Posted on 2018-04-24

454 MSPminer: abundance-based reconstitution of microbial pan-genomes from shotgun metagenomic data

Plaza Onate, F.; Le Chatelier, E.; Almeida, M.; Cervino, A. C. L.; Gauthier, F.; Magoules, F.; Ehrlich, S. D.; Pichaud, M.

10.1101/173203 — bioinformatics — Posted on 2018-04-24

455 Regime shifts and hysteresis in the pitcher-plant microecosystem

Lau, M. K.; Baiser, B.; Northrop, A.; Gotelli, N. J.; Ellison, A. M.

10.1101/087296 — ecology — Posted on 2018-04-24

456 Genetic analysis of RNA polymerase I unveils new role of the Rpa12 subunit during transcription

Darriere, T.; Pilsl, M.; Chauvier, A.; Genty, T.; Audibert, S.; Dez, C.; Leger-Silvestre, I.; Normand, C.; Calvo, O.; Fernandez-Tornero, C.; Tschochner, H.; Gadal, O.

10.1101/307199 — molecular biology — Posted on 2018-04-24

457 Aggressive or moderate drug therapy for infectious diseases? Trade-offs between different treatment goals at the individual and population levels

Scire, J.; Hoze, N.; Uecker, H.

10.1101/307223 — epidemiology — Posted on 2018-04-24

458 Measuring the Impact of an Open Online Prescribing Data Analysis Service on Clinical Practice: a Cohort Study in NHS England Data

Walker, A. J.; Curtis, H. J.; Croker, R.; Bacon, S.; Goldacre, B.

10.1101/306415 — epidemiology — Posted on 2018-04-24

459 Ankyrin-G Regulates Forebrain Connectivity and Network Synchronization via Interaction with GABARAP

Nelson, A. D.; Caballero-Floran, R. N.; Rodriguez Diaz, J. C.; Li, J.; Chen, K.; Walder, K. K.; Bennett, V.; Lopez-Santiago, L. F.; McInnis, M. G.; Isom, L. L.; Wang, C.; Zhang, M.; Jones, K. S.; Jenkins, P. M.

10.1101/307512 — neuroscience — Posted on 2018-04-24

460 Vacuolar iron stores gated by NRAMP3 and NRAMP4 are the primary source of iron in germinating seeds

Bastow, E. L.; Garcia de la Torre, V. S.; Maclean, A. E.; Green, R. T.; Merlot, S.; Thomine, S.; Balk, J.

10.1101/306894 — plant biology — Posted on 2018-04-24

461 A High-Throughput Pipeline Identifies Robust Connectomes But Troublesome Variability

Kiar, G.; Bridgeford, E.; Roncal, W. G.; Consortium for Reliability and Reproducibliity (CoRR), ; Chandrashekhar, V.; Mhembere, D.; Ryman, S.; Zuo, X.-N.; Marguiles, D. S.; Craddock, R. C.; Priebe, C. E.; Jung, R.; Calhoun, V.; Caffo, B.; Burns, R.; Milham, M. P.; Vogelstein, J.

10.1101/188706 — neuroscience — Posted on 2018-04-24

462 Multinucleotide mutations cause false inferences of lineage-specific positive selection

Venkat, A.; Hahn, M. W.; Thornton, J. W.

10.1101/165969 — evolutionary biology — Posted on 2018-04-24

463 How the Central American Seaway and an ancient northern passage affected flatfish diversification

Byrne, L.; Chapleau, F.; Aris-Brosou, S.

10.1101/247304 — evolutionary biology — Posted on 2018-04-24

464 An alternative mode of epithelial polarity in the Drosophila midgut

Chen, J.; Sayadian, A.-C.; Lowe, N.; Lovegrove, H.; St Johnston, D.

10.1101/307579 — cell biology — Posted on 2018-04-24

465 Sensations from a single M-cone depend on the activity of surrounding S-cones

Schmidt, B. P.; Sabesan, R.; Tuten, W. S.; Neitz, J.; Roorda, A.

10.1101/260653 — neuroscience — Posted on 2018-04-24

466 Partial ablation of the orexin field induces a sub narcoleptic phenotype in a conditional mouse model of orexin neurodegeneration

Black, S. W.; Sun, J. D.; Santiago, P.; Laihsu, A.; Kimura, N.; Yamanaka, A.; Bersot, R.; Humphries, P. S.

10.1101/234765 — neuroscience — Posted on 2018-04-24

467 Synthetic methanogenic communities reveal differential impact of ecological perturbations on aceto- and hydrogeno-trophic methanogens

Chen, J.; Wade, M.; Dolfing, J.; soyer, o.

10.1101/307041 — synthetic biology — Posted on 2018-04-24

468 Dissociable roles for the rTPJ and dmPFC in self-other processing: a HD-tDCS study

Martin, A. K.; Huang, J.; Meinzer, M.

10.1101/306183 — neuroscience — Posted on 2018-04-24

469 Acute-stress impairs cytoprotective mechanisms through neural inhibition of the insulin pathway

De Rosa, M. J.; Veuthey, T.; Florman, J.; Grant, J.; Blanco, G.; Andersen, N.; Donnelly, J.; Rayes, D.; Alkema, M.

10.1101/294645 — neuroscience — Posted on 2018-04-24

470 Catecholamine Challenge Uncovers Distinct Mechanisms For Direct Versus Indirect, But Not Social Versus Non-Social, Learning

Cook, J. L.; Swart, J. C.; Frobose, M. I.; Diaconescu, A.; Geurts, D. E. M.; den Ouden, H. E. M.; Cools, R.

10.1101/303982 — neuroscience — Posted on 2018-04-24

471 The Reach Cage environment for wireless neural recordings during structured goal-directed behavior of unrestrained monkeys

Berger, M.; Gail, A.

10.1101/305334 — neuroscience — Posted on 2018-04-24

472 TRPML1-mediated Modulation of Dense-core Granules Tunes Functional Potential in NK Cells

Goodridge, J. P.; Jacobs, B.; Satersmoen, M. L.; Clement, D.; Clancy, T.; Skarpen, E.; Brech, A.; Landskron, J.; Grimm, C.; Pfefferle, A.; Meza-Zepeda, L.; Lorenz, S.; Wiiger, M. T.; Louch, W. E.; Ask, E. H.; Liu, L. L.; Oei, V. Y. S.; Kjallquist, U.; Linnarsson, S.; Patel, S.; Tasken, K.; Stenmark, H.; Malmberg, K.-J.

10.1101/305862 — immunology — Posted on 2018-04-24

473 Improved estimation of cancer dependencies from large-scale RNAi screens using model-based normalization and data integration

McFarland, J. M.; Ho, Z. V.; Kugener, G.; Dempster, J. M.; Montgomery, P. G.; Bryan, J. G.; Krill-Burger, J. M.; Green, T. M.; Vazquez, F.; Boehm, J. S.; Golub, T. R.; Hahn, W. C.; Root, D. E.; Tsherniak, A.

10.1101/305656 — genomics — Posted on 2018-04-24

474 HMMRATAC, the Hidden Markov ModeleR for ATAC-seq

Tarbell, E. D.; Liu, T.

10.1101/306621 — bioinformatics — Posted on 2018-04-24

475 Autotransporter secretion exploits the bacterial actin-homologue

Ashawesh, M.; Markus, R.; Penfold, C.; Hardie, K.

10.1101/305441 — microbiology — Posted on 2018-04-24

476 Dynamic linear models guide design and analysis of microbiota studies within artificial human guts

Silverman, J. D.; Durand, H.; Bloom, R. J.; Mukherjee, S.; David, L. A.

10.1101/306597 — genomics — Posted on 2018-04-24

477 Geometric morphometrics of nested symmetries: Hierarchical inter- and intra-individual variation in biological shapes

Savriama, Y.; Gerber, S.

10.1101/306712 — evolutionary biology — Posted on 2018-04-24

478 A common statistical misunderstanding in Psychology and Neuroscience: Do we need normally distributed independent or dependent variables for linear regression to work?

Habeck, C.; Brickman, A.

10.1101/305946 — scientific communication and education — Posted on 2018-04-24

479 A rapid microwave method for isolation of genomic DNA and identification of white rot fungi.

Rao, R. G.; Ravichandran, A.; Dhali, A.; Kolte, A. P.; Kandalam, G.; Sridhar, M.

10.1101/307066 — molecular biology — Posted on 2018-04-24

480 A direct proof that sole actin dynamics drive membrane deformations

Simon, C.; Kusters, R.; Caorsi, V.; Allard, A.; Abou-Ghali, M.; Manzi, J.; Di Cicco, A.; Levy, D.; Lenz, M.; Joanny, J.-F.; Campillo, C.; Plastino, J.; Sens, P.; Sykes, C.

10.1101/307173 — biophysics — Posted on 2018-04-24

481 Single cell RNAseq uncovers a robust transcriptional response to morphine by oligodendrocytes

Avey, D.; Sankararaman, S.; Yim, A. K. Y.; Barve, R.; Mitra, R. D.; Milbrandt, J.

10.1101/306944 — neuroscience — Posted on 2018-04-24

482 Exocyst subcomplex functions in autophagosome biogenesis by regulating Atg9 trafficking

Rajput, S. S.; Chinchwadkar, S.; Aher, A.; Matheshwaran, S.; Manjithaya, R.

10.1101/306969 — cell biology — Posted on 2018-04-24

483 Causal Evidence for the Dependence of the Magnitude Effect on Dorsolateral Prefrontal Cortex

Ballard, I. C.; Aydogan, G.; Kim, B.; McClure, S.

10.1101/306746 — neuroscience — Posted on 2018-04-23

484 Expression of a glucomannan mannosyltransferase gene (GMMT) from Aloe vera is induced by water deficit and abscisic acid.

Salinas, C. P.; Salinas, C. A.; Contreras, R.; Zuniga, G.; Dupree, P.; Cardemil, L. A.

10.1101/306829 — plant biology — Posted on 2018-04-23

485 Single-cell phenotyping and RNA sequencing reveal novel patterns of gene expression heterogeneity and regulation during growth and stress adaptation in a unicellular eukaryote

Saint, M.; Bertaux, F.; Tang, W.; Sun, X.-M.; Game, L.; Köferle, A.; Bähler, J.; Shahrezaei, V.; Marguerat, S.

10.1101/306795 — genomics — Posted on 2018-04-23

486 Extraordinary genome instability and widespread chromosome rearrangements during vegetative growth

Moeller, M.; Habig, M.; Freitag, M.; Holtgrewe Stukenbrock, E.

10.1101/304915 — genomics — Posted on 2018-04-23

487 A study of analytical strategies to include X-chromosome in variance heterogeneity analysis: evidence for trait-specific polygenic variance structure

Deng, W.; Kalnapenkis, A.; Mao, S.; Magi, R.; Esko, T.; Pare, G.; Sun, L.

10.1101/306654 — genetics — Posted on 2018-04-23

488 The SERM/SERD Bazedoxifene Disrupts ESR1 Helix 12 to Overcome Acquired Hormone Resistance in Breast Cancer Cells

Fanning, S. W.; Jeselsohn, R.; Dharmarajan, V.; Mayne, C. G.; Karimi, M.; Buchwalter, G.; Houtman, R.; Toy, W.; Fowler, C. E.; Laine, M.; Carlson, K. E.; Martin, T. A.; Nowak, J.; Nwachukwu, J. C.; Hosfield, D. J.; Chandarlapaty, S.; Tajkhorshid, E.; Nettles, K. W.; Griffin, P. R.; Shen, Y.; Katzenellenbogen, J. A.; Brown, M.; Greene, G. L.

10.1101/306472 — cancer biology — Posted on 2018-04-23

489 A New Approach to Symmetric Registration of Longitudinal Structural MRI of the Human Brain

Ardekani, B. A.

10.1101/306811 — bioinformatics — Posted on 2018-04-23

490 Deciphering the Dynamics of Interlocked Feedback Loops in a Model of the Mammalian Circadian Clock

Battogtokh, D.; Tyson, J. J.

10.1101/306852 — systems biology — Posted on 2018-04-23

491 Intrinsic Excitability Increase in Cerebellar Purkinje Cells Following Delay Eyeblink Conditioning in Mice

Titley, H. K.; Watkins, G. V.; Lin, C.; Weiss, C.; McCarthy, M.; Disterhoft, J. F.; Hansel, C.

10.1101/306639 — neuroscience — Posted on 2018-04-23

492 Joint Modeling of Reaction Times and Choice Improves Parameter Identifiability in Reinforcement Learning Models

Ballard, I. C.; McClure, S. M.

10.1101/306720 — neuroscience — Posted on 2018-04-23

493 Maternal pluripotency factors prime the zygotic genome to respond to intercellular signals

Gentsch, G. E.; Spruce, T.; Owens, N. D. L.; Smith, J. C.

10.1101/306803 — developmental biology — Posted on 2018-04-23

494 Cooperate-and-radiate co-evolution between ants and plants

Kaur, K. M.; Male, P.-J. G.; Spence, E.; Gomez, C.; Frederickson, M. E.

10.1101/306787 — evolutionary biology — Posted on 2018-04-23

495 A major locus for ivermectin resistance in a parasitic nematode

Doyle, S. R.; Illingworth, C. J. R.; Laing, R.; Bartley, D. J.; Redman, E.; Martinelli, A.; Holroyd, N.; Morrison, A. A.; Rezansoff, A.; Tracey, A.; Devaney, E.; Berriman, M.; Sargison, N.; Cotton, J. A.; Gilleard, J. S.

10.1101/298901 — genomics — Posted on 2018-04-23

496 CTC Marker CD117/c-kit Represents a Prostate Cancer Stem-Like Subpopulation Driving Progression, Migration, and TKI Resistance

Harris, K.; Foster, B.; Shi, L.; Mobley, M.; Elliott, P.; Kerr, B.

10.1101/256107 — cancer biology — Posted on 2018-04-23

497 Whole Exome Sequencing in 20,197 Persons for Rare Variants in Alzheimer Disease

Raghavan, N. S.; Brickman, A. M.; Andrews, H.; Manly, J. J.; Schupf, N.; Lantigua, R.; The Alzheimers Disease Sequencing Project, ; Wolock, C. J.; Kamalakaran, S.; Petrovski, S.; Tosto, G.; Vardarajan, B. N.; Goldstein, D. B.; Mayeux, R.

10.1101/305631 — genetics — Posted on 2018-04-23

498 Transcription Factor Regulation of RNA polymerase’s Torsional Capacity

Ma, J.; Tan, C.; Gao, X.; Fulbright, R.; Roberts, J.; Wang, M. D.

10.1101/306258 — biophysics — Posted on 2018-04-23

499 Estrogen receptor regulates hormone-induced growth arrest in a luminal A like breast cancer model

Haddon, L.; Hu, S.; Jabbari, H.; Loney, B.; Lichtensztejn, Z.-S.; Fahlman, R.; Hitt, M.; McManus, K.; Dabbs, K.; Mackey, J.; Hugh, J.

10.1101/306662 — pathology — Posted on 2018-04-23

500 Physical and functional cell-matrix uncoupling in a developing tissue under tension

Suzanne, M.; Proag, A.; Monier, B.

10.1101/306696 — cell biology — Posted on 2018-04-23

501 The dynamics of ERK signaling in melanoma, and the response to BRAF or MEK inhibition, are cell cycle dependent.

Simpson, C. M.; Bakal, C.

10.1101/306571 — cancer biology — Posted on 2018-04-23

502 Simulation of spontaneous G protein activation reveals a new intermediate driving GDP unbinding

Sun, X.; Singh, S.; Blumer, K. J.; Bowman, G. R.

10.1101/306647 — biophysics — Posted on 2018-04-23

503 Unraveling the mechanism of the cadherin-catenin-actin catch bond

Adhikari, S.; Moran, J.; Weddle, C.; Hinczewski, M.

10.1101/306761 — biophysics — Posted on 2018-04-23

504 Discovering novel calcineurin inhibitors through quantitative mapping of protein-peptide affinity landscapes

Nguyen, H. Q.; Roy, J.; Harink, B.; Damle, N.; Baxter, B.; Brower, K.; Kortemme, T.; Thorn, K.; Cyert, M.; Fordyce, P. M.

10.1101/306779 — bioengineering — Posted on 2018-04-23

505 Genetic and Epigenetic Determinants Establish a Continuum of Hsf1 Occupancy and Activity Across the Yeast Genome

Pincus, D.; Anandhakumar, J.; Thiru, P.; Guertin, M. J.; Erkine, A. M.; Gross, D. S.

10.1101/306704 — genomics — Posted on 2018-04-23

506 Identification and Quantification of Paclitaxel and its Metabolites in Human Meconium from Newborns with Gestational Chemotherapeutic Exposure

Cardonick, E.; Broadrup, R.; Xu, P.; Doan, M. T.; Jiang, H.; Snyder, N.

10.1101/306274 — pharmacology and toxicology — Posted on 2018-04-23

507 Evaluation of lung VEGF-A transduction during hyperoxia-induced injury in rats

Raoul, W.; Louzier, V.; Eddahibi, S.; Adnot, S.; Maitre, B.; Delclaux, C.

10.1101/306381 — pathology — Posted on 2018-04-23

508 Angiodysplasia Detection and Localization Using Deep Convolutional Neural Networks

Shvets, A.; Iglovikov, V.; Rakhlin, A.; Kalinin, A. A.

10.1101/306159 — pathology — Posted on 2018-04-23

509 Humans incorporate trial-to-trial working memory uncertainty into rewarded decisions

Honig, M.; Ma, W. J.; Fougnie, D.

10.1101/306225 — neuroscience — Posted on 2018-04-23

510 Field synopsis and systematic meta-analyses of genetic association studies in isolated dystonia

Ohlei, O.; Dobricic, V.; Lohmann, K.; Klein, C.; Lill, C. M.; Bertram, L.

10.1101/306522 — neuroscience — Posted on 2018-04-23

511 Levodopa and dopamine dynamics in Parkinson’s disease metabolomics

Branco, R. C.; Ellsworth, W.; Niezwiecki, M. M.; Butkovich, L. M.; Walker, D. I.; Huddleston, D. E.; Jones, D. P.; Miller, G. W.

10.1101/306266 — neuroscience — Posted on 2018-04-23

512 A Single Mechanism of Biogenesis, Initiated and Directed by PIWI Proteins, Explains piRNA Production in Most Animals

Zamore, P.; Gainetdinov, I.; Colpan, C.; Cecchini, K.

10.1101/261545 — molecular biology — Posted on 2018-04-23

513 Multi-Hierarchical Dynamics of Antimicrobial Resistance Simulated in a Nested Membrane Computing Model

Campos, M.; Capilla, R.; Llorens, C.; Canton, R.; Moya, A.; Sempere, J.-M.; Coque, T.; Fernandez-Lanza, V.; Naya, F.; Futami, R.; Baquero, F.

10.1101/306100 — microbiology — Posted on 2018-04-23

514 Cognate T and B cell interaction and association of Follicular helper T cells with B cell responses in Vibrio cholerae O1 infected Bangladeshi adults

Rashu, R.; Bhuiyan, T. R.; Hoq, M. R.; Hossain, L.; Paul, A.; Khan, A. I.; Chowdhury, F.; Harris, J. B.; Ryan, E. T.; Calderwood, S. B.; Weil, A. A.; Qadri, F.

10.1101/306365 — immunology — Posted on 2018-04-23

515 Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1

Xu, K.; Acharya, P.; Kong, R.; Cheng, C.; Chuang, G.-Y.; Liu, K.; Louder, M. K.; O Dell, S.; Rawi, R.; Sastry, M.; Shen, C.-H.; Zhang, B.; Zhou, T.; Asokan, M.; Bailer, R. T.; Chambers, M.; Chen, X.; Choi, C. W.; Dandey, V. P.; Doria-Rose, N. A.; Druz, A.; Eng, E. T.; Farney, S. K.; Foulds, K. E.; Geng, H.; Georgiev, I. S.; Gorman, J.; Hill, K. R.; Jafari, A. J.; Kwon, Y. D.; Lai, Y.-T.; Lemmin, T.; McKee, K.; Ohr, T. Y.; Ou, L.; Peng, D.; Rowshan, A. P.; Sheng, Z.; Todd, J.-P.; Tsybovsky, Y.; Viox, E. G.; Wang, Y.; Wei, H.; Yang, Y.; Zhou, A. F.; Chen, R.; Yang, L.; Scorpio, D. G.; McDermott,

10.1101/306282 — immunology — Posted on 2018-04-23

516 Software-assisted manual review of clinical NGS data:an alternative to routine Sanger sequencing confirmationwith equivalent results in >15,000 hereditary cancer screens

Muzzey, D.; Kash, S.; Johnson, J. I.; Melroy, L. M.; Kaleta, P.; Pierce, K. A.; Ready, K.; Kang, H. P.; Haas, K. R.

10.1101/305011 — genomics — Posted on 2018-04-23

517 A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score

Curtis, D.

10.1101/306191 — genetics — Posted on 2018-04-23

518 Cyclic dominance emerges from the evolution of two inter-linked cooperative behaviours in the social amoeba

Shibasaki, S.; Shimada, M.

10.1101/251553 — evolutionary biology — Posted on 2018-04-23

519 Understanding the regulation of STIM1-ORAI1 interaction using a reaction-diffusion model

Schmidt, B.; Bogeski, I.; Niemeyer, B. A.; Rieger, H.

10.1101/306530 — biophysics — Posted on 2018-04-23

520 Dynamics of Allosteric Transitions in Dynein

Goldtzvik, Y.; Mugnai, M. L.; Thirumalai, D.

10.1101/306589 — biophysics — Posted on 2018-04-23

521 CHOP: Haplotype-aware path indexing in population graphs

Mokveld, T. O.; Linthorst, J.; Al-Ars, Z.; Reinders, M.

10.1101/305268 — bioinformatics — Posted on 2018-04-23

522 Prot-SpaM: Fast alignment-free phylogeny reconstruction based on whole-proteome sequences

Leimeister, C.-A.; Schellhorn, J.; Schoebel, S.; Gerth, M.; Bleidorn, C.; Morgenstern, B.

10.1101/306142 — bioinformatics — Posted on 2018-04-23

523 Metabolic Reaction Network-based Recursive Metabolite Identification for Untargeted Metabolomics

Shen, X.; Xiong, X.; Wang, R.; Yin, Y.; Cai, Y.; Ma, Z.; Liu, N.; Zhu, Z.-J.

10.1101/305201 — bioinformatics — Posted on 2018-04-23

524 OSPREY 3.0: Open-Source Protein Redesign for You, with Powerful New Features

Hallen, M. A.; Martin, J. W.; Ojewole, A.; Jou, J. D.; Lowegard, A. U.; Frenkel, M. S.; Gainza, P.; Nisonoff, H. M.; Mukund, A.; Wang, S.; Holt, G. T.; Zhou, D.; Dowd, E.; Donald, B. R.

10.1101/306324 — bioinformatics — Posted on 2018-04-23

525 Revelation of a Novel Protein Translocon in Bacterial Plasma Membrane

Jin, F.; Chang, Z.

10.1101/121335 — biochemistry — Posted on 2018-04-23

526 Exploring the mechanistic link between corticosterone and insulin-like growth factor-1 in a wild passerine bird

Toth, Z.; Ouyang, J. Q.; Lendvai, A. Z.

10.1101/306407 — physiology — Posted on 2018-04-23

527 An individual differences approach to semantic cognition: Divergent effects of age on representation, retrieval and selection

Hoffman, P.

10.1101/182170 — neuroscience — Posted on 2018-04-23

528 First in-human PET study of 3 novel tau radiopharmaceuticals: RO6958948

Wong, D. F.; Comley, R. A.; Kuwabara, H.; Rosenberg, P.; Resnick, S. M.; Ostrowitzki, S.; Vozzi, C.; Boess, F.; Oh, E.; Lyketsos, C. G.; Horner, M.; Gobbi, L.; Klein, G.; George, N.; Gapasin, L.; Kitzmiller, K.; Roberts, J.; Sevigny, J.; Nandi, A.; Brasic, J.; Mishra, C.; Thambisetty, M.; Mogekar, A.; Mathur, A.; Albert, M.; Dannals, R. F.; Borroni, E.

10.1101/296764 — neuroscience — Posted on 2018-04-23

529 Transient Magnetothermal Neuronal Silencing using the Chloride Channel Anoctamin1 (TMEM16A)

Munshi, R.; Qadri, S. M.; Pralle, A.

10.1101/306555 — neuroscience — Posted on 2018-04-23

530 How to control for confounds in decoding analyses of neuroimaging data

Snoek, L.; Miletic, S.; Scholte, H. S.

10.1101/290684 — neuroscience — Posted on 2018-04-23

531 Staphylococcus aureus toxin LukSF dissociates from its membrane receptor target to enable renewed ligand sequestration

Haapasalo, K.; Wollman, A.; de Haas, C.; van Kessel, K.; van Strijp, J.; Leake, M. C.

10.1101/251645 — microbiology — Posted on 2018-04-23

532 High coverage genome sequencing and identification of genomic variants in Bengal tiger (Panthera tigris tigris)

Reddy, A. P.; Kothandaraman, H.; Arun, P. V. P. S.; Challagandla, A.; Baghel, D. S.

10.1101/306399 — genomics — Posted on 2018-04-23

533 Functional architecture of deleterious genetic variants in the Wrangel Island mammoth genome

Fry, E.; Kim, S. K.; Chigurapti, S.; Mika, K. M.; Ratan, A.; Dammermann, A.; Mitchell, B. J.; Miller, W.; Lynch, V. J.

10.1101/137455 — genetics — Posted on 2018-04-23

534 Collapse and rescue of cooperation in evolving dynamic networks

Akcay, E.

10.1101/226563 — evolutionary biology — Posted on 2018-04-23

535 Genomic Data from an Endangered Amphibian Reveal Unforeseen Consequences of Fragmentation by Roads

McCartney-Melstad, E.; Vu, J. K.; Shaffer, H. B.

10.1101/306340 — evolutionary biology — Posted on 2018-04-23

536 Separate the wheat from the chaff: genomic analysis of local adaptation in the red coral Corallium rubrum

Pratlong, M.; Haguenauer, A.; Brener, K.; Mitta, G.; Toulza, E.; Garrabou, J.; Bensoussan, N.; Pontarotti, P.; Aurelle, D.

10.1101/306456 — evolutionary biology — Posted on 2018-04-23

537 Naa15 knockdown enhances c2c12 myoblast fusion and induces defects in zebrafish myotome morphogenesis

Monestier, O.; Landemaine, A.; Bugeon, J.; Rescan, P.-Y.; Gabillard, J.-C.

10.1101/306563 — cell biology — Posted on 2018-04-23

538 Self-organised segregation of bacterial chromosomal origins

Murray, S. M.; Sourjik, V.

10.1101/304600 — biophysics — Posted on 2018-04-23

539 Single-molecule diffusion-based estimation of ligand effects on G protein-coupled receptors

Yanagawa, M.; Hiroshima, M.; Togashi, Y.; Abe, M.; Yamashita, T.; Shichida, Y.; Murata, M.; Ueda, M.; Sako, Y.

10.1101/205161 — biophysics — Posted on 2018-04-23

540 Statistical machine learning of sleep and physical activity phenotypes from sensor data in 96,220 UK Biobank participants

Willetts, M.; Hollowell, S.; Aslett, L.; Holmes, C.; Doherty, A.

10.1101/187625 — bioinformatics — Posted on 2018-04-23

541 Macrophage Il-1beta protects against mycobacterial infection downstream of Hif-1alpha in zebrafish

Ogryzko, N. V.; Lewis, A.; Wilson, H. L.; Meijer, A. H.; Renshaw, S. A.; Elks, P. M.

10.1101/306506 — immunology — Posted on 2018-04-23

542 Myelinated inhibitory axons in human neocortex

Micheva, K. D.; Chang, E. F.; Nana, A. L.; Seeley, W. W.; Ting, J. T.; Cobbs, C.; Lein, E.; Smith, S. J.; Weinberg, R. J.; Madison, D. V.

10.1101/306480 — neuroscience — Posted on 2018-04-23

543 Shifts in the gut microbiota structure caused by Helicobacter pylori eradication therapy

10.1101/296426 — microbiology — Posted on 2018-04-23

544 Cell type identity determines transcriptomic immune responses in Arabidopsis thaliana roots.

Rich, C.; Reitz, M.; Eichmann, R.; Hermann, S.; Jenkins, D. J.; Kogel, K.-H.; Esteban, E.; Ott, S.; Schafer, P.

10.1101/302448 — plant biology — Posted on 2018-04-23

545 Generalised free energy and active inference: can the future cause the past?

Parr, T.; Friston, K. J.

10.1101/304782 — neuroscience — Posted on 2018-04-23

546 Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study

Carter, A. R.; Borges, M.-C.; Benn, M.; Tybjaerg-Hansen, A.; Smith, G. D.; Nordestgaard, B. G.; Lawlor, D. A.

10.1101/303313 — epidemiology — Posted on 2018-04-23

547 De novo protein structure prediction using ultra-fast molecular dynamics simulation

Cheung, N. J.; Yu, W.

10.1101/262188 — bioinformatics — Posted on 2018-04-23

548 Rethomics: an R framework to analyse high-throughput behavioural data

Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; Gilestro, G. F.

10.1101/305664 — bioinformatics — Posted on 2018-04-23

549 q2-sample-classifier: machine-learning tools for microbiome classification and regression

Bokulich, N.; Dillon, M.; Bolyen, E.; Kaehler, B. D.; Huttley, G. A.; Caporaso, J. G.

10.1101/306167 — bioinformatics — Posted on 2018-04-23

550 Glial cells in the heart? Replicating the diversity of the myocardium with low-cost 3D models

Soucy, J. R.; Askaryan, J.; Diaz, D.; Koppes, A. N.; Annabi, N.; Koppes, R.

10.1101/306233 — bioengineering — Posted on 2018-04-23

551 Artefactual formation of pyruvate from in-source conversion of lactate

Snyder, N. W.; Trefely, S.; Mesaros, C.; Xu, P.; Doan, M.; Jiang, H.; Altinok, O.; Orynbayeva, Z.

10.1101/256271 — biochemistry — Posted on 2018-04-23

552 Lost in Space: The Impact of Traditional Neuroimaging Methods on the Spatial Localization of Cortical Areas

Coalson, T. S.; Van Essen, D. C.; Glasser, M. F.

10.1101/255620 — neuroscience — Posted on 2018-04-23

553 Gene Set Enrichment Analysis (GSEA) of Upregulated Genes in Cocaine Addiction Reveals miRNAs as Potential Therapeutic Agents

Ahammad, I.

10.1101/303362 — bioinformatics — Posted on 2018-04-23

554 Diversity of feature selectivity in macaque visual cortex arising from limited number of broadly-tuned input channels

Mohan, Y. S.; Jayakumar, J.; Lloyd, E. K. J.; Levichkina, E.; Vidyasagar, T.

10.1101/291229 — neuroscience — Posted on 2018-04-23

555 Genetic patterning in Central Eurasia: population history and pigmentation

Royrvik, E. C.; Yuldasheva, N.; Tonks, S.; Winney, B.; Ruzibakiev, R.; Wells, R. S.; Bodmer, W. F.

10.1101/255117 — genetics — Posted on 2018-04-23

556 Molecular atlas of postnatal mouse heart development

Talman, V.; Teppo, J.; Poho, P.; Movahedi, P.; Vaikkinen, A.; Karhu, T.; Trost, K.; Suvitaival, T.; Heikkonen, J.; Pahikkala, T.; Kotiaho, T.; Kostiainen, R.; Varjosalo, M.; Ruskoaho, H.

10.1101/302802 — systems biology — Posted on 2018-04-23

557 Aspergillus niger citrate exporter revealed by comparison of two alternative citrate producing conditions

Odoni, D. I.; Laothanachareon, T.; Vazquez-Vilar, M.; van Gaal, M. P.; Schonewille, T.; Bruinsma, L.; Martins dos Santos, V. A.; Tamayo-Ramos, J. A. A.; Suarez-Diez, M.; Schaap, P. J.

10.1101/259051 — molecular biology — Posted on 2018-04-23

558 Complementary chromosome folding by transcription factors and cohesin

Pereira, M. C. F.; Brackley, C. A.; Michieletto, D.; Annunziatella, C.; Bianco, S.; Chiariello, A. M.; Nicodemi, M.; Marenduzzo, D.

10.1101/305359 — biophysics — Posted on 2018-04-23

559 High Resolution Single Particle Cryo-Electron Microscopy using Beam-Image Shift

Cheng, A.; Eng, E. T.; Alink, L.; Rice, W. J.; Jordan, K. D.; Kim, L. Y.; Potter, C. S.; Carraggher, B.

10.1101/306241 — biophysics — Posted on 2018-04-23

560 LONP1 is required for maturation of a subset of mitochondrial proteins and its loss elicits an integrated stress response

Zurita Rendon, O.; Shoubridge, E. A.

10.1101/306316 — biochemistry — Posted on 2018-04-23

561 Patterns of reduced cortical thickness and striatum pathological morphology in cocaine addiction.

Garza-Villarreal, E. A.; Alcala, R.; Balducci, T.; Angeles-Valdez, D.; Chakravarty, M.; Devenyi, G. A.; Gonzalez-Olvera, J. J.

10.1101/306068 — neuroscience — Posted on 2018-04-22

562 Three invariant Hi-C interaction patterns: applications to genome assembly

Oddes, S.; Zelig, A.; Kaplan, N.

10.1101/306076 — genomics — Posted on 2018-04-22

563 Maternal Plag1 deficiency delays zygotic genome activation and two-cell stage embryo development

Madissoon, E.; Damdimopoulos, A.; Katayama, S.; Krjutskov, K.; Einarsdottir, E.; Mamia, K.; De Groef, B.; Hovatta, O.; Kere, J.; Damdimopoulou, P.

10.1101/305375 — developmental biology — Posted on 2018-04-22

564 Inter-institutional variation in predictive value of the ThyroSeq v2 genomic classifier for cytologically indeterminate thyroid nodules

Marcadis, A. R.; Valderrabano, P.; Ho, A. S.; Tepe, J.; Swartzwelder, C. E.; Byrd, S.; Sacks, W. L.; Untch, B. R.; Shaha, A. R.; Xu, B.; Lin, O.; Ghossein, R. A.; Wong, R. J.; Marti, J. L.; Morris, L. G. T.

10.1101/306126 — cancer biology — Posted on 2018-04-22

565 DNA polymerase β fingers movement revealed by single-molecule FRET suggests a partially closed conformation as a fidelity checkpoint

Fijen, C.; Mahmoud, M.; Kaup, R.; Towle-Weicksel, J.; Sweasy, J.; Hohlbein, J.

10.1101/306175 — biophysics — Posted on 2018-04-22

566 Heterogeneous local dynamics revealed by classification analysis of spatially disaggregated time series data

Perkins, A.; Rodriguez-Barraquer, I.; Manore, C.; Siraj, A.; Espana, G.; Barker, C.; Johansson, M.; Reiner, R.

10.1101/276006 — epidemiology — Posted on 2018-04-22

567 Rarity and conservation status do not predict vertebrate population trends

Daskalova, G. N.; Myers-Smith, I. H.; Godlee, J. L.

10.1101/272898 — ecology — Posted on 2018-04-22

568 3D Cell Nuclear Morphology: Microscopy Imaging Dataset and Voxel-Based Morphometry Classification Results

Kalinin, A. A.; Allyn-Feuer, A.; Ade, A.; Fon, G.-V.; Meixner, W.; Dilworth, D.; de Wet, J. R.; Higgins, G. A.; Zheng, G.; Creekmore, A.; Wiley, J. W.; Verdone, J. E.; Veltri, R. W.; Pienta, K. J.; Coffey, D. S.; Athey, B. D.; Dinov, I. D.

10.1101/208207 — bioinformatics — Posted on 2018-04-22

569 Perimenstrual Exacerbation of Symptoms in Borderline Personality Disorder: Evidence from Multilevel Models and the Carolina Premenstrual Assessment Scoring System

Eisenlohr-Moul, T.; Schmalenberger, K. M.; Owens, S. A.; Peters, J. R.; Dawson, D. N.; Girdler, S. S.

10.1101/192658 — neuroscience — Posted on 2018-04-22

570 Fast and Simple Tool for the Quantification of Biofilm-Embedded Cells Sub-Populations From Fluorescent Microscopic Images

Bogachev, M.; Volkov, V.; Markelov, O.; Trizna, E.; Baydamshina, D.; Melnikov, V.; Zelenikhin, P.; Murtazina, R.; Sharafutdinov, I.; Kayumov, A.

10.1101/181495 — microbiology — Posted on 2018-04-22

571 Quantitative imaging of chromatin decompaction in living cells

Dultz, E.; Mancini, R.; Polles, G.; Vallotton, P.; Alber, F.; Weis, K.

10.1101/219253 — cell biology — Posted on 2018-04-22

572 Exploration and generalization in vast spaces

Wu, C. M.; Schulz, E.; Speekenbrink, M.; Nelson, J. D.; Meder, B.

10.1101/171371 — animal behavior and cognition — Posted on 2018-04-22

573 Pattern of severe injuries in Spanish children: boys and falls are alarmingly overrepresented

Benito, S.; Lopez-Parellada, R.; Esteban, E.; Hernandez, L.; Prat, S.; Esparza, M.; Cambra, F. J.; Esteban, M. E.

10.1101/303958 — epidemiology — Posted on 2018-04-22

574 Large-scale organization of the hand action observation network in individuals born without hands

Vannuscorps, G.; Wurm, M.; Striem-Amit, E.; Caramazza, A.

10.1101/305888 — neuroscience — Posted on 2018-04-22

575 Probing developmental patterns of intracortical myelination using gray/white matter contrast and associations with cognitive abilities and psychopathology in youth

Norbom, L. B.; Doan, N. T.; Alnaes, D.; Kaufmann, T.; Moberget, T.; Rokicki, J.; Andreassen, O. A.; Westlye, L. T.; Tamnes, C. K.

10.1101/305995 — neuroscience — Posted on 2018-04-22

576 Molecular genetic analysis of Steroid Resistant Nephrotic Syndrome: Detection of a novel mutation

Serajpour, N.; Karimi, B.; Hooman, N.; Hosseini, R.; Khosravi, P.; Milo Rasouly, H.; Shojaei, A.

10.1101/305987 — genetics — Posted on 2018-04-22

577 Automated delineation of non-small cell lung cancer

Saad, M. B.

10.1101/304949 — bioinformatics — Posted on 2018-04-22

578 The effect of acquisition resolution on orientation decoding from V1: comparison of 3T and 7T

Sengupta, A.; Speck, O.; Yakupov, R.; Kanowski, M.; Tempelmann, C.; Pollmann, S.; Hanke, M.

10.1101/305417 — neuroscience — Posted on 2018-04-22

579 Virtual navigation tested on a mobile app (Sea Hero Quest) is predictive of real-world navigation performance: preliminary data

Coutrot, A.; Schmidt, S.; Pittman, J.; Hong, L.; Wiener, J. M.; Holscher, C.; Dalton, R. C.; Hornberger, M.; Spiers, H. J.

10.1101/305433 — neuroscience — Posted on 2018-04-22

580 How thalamic relays might orchestrate supervised deep training and symbolic computation in the brain

Hayworth, K. J.; Marblestone, A. H.

10.1101/304980 — neuroscience — Posted on 2018-04-22

581 Software-assisted manual review of clinical NGS data:an alternative to routine Sanger sequencing confirmationwith equivalent results in >15,000 hereditary cancer screens

Muzzey, D.; Kash, S.; Johnson, J. I.; Melroy, L. M.; Kaleta, P.; Pierce, K. A.; Ready, K.; Kang, H. P.; Haas, K. R.

10.1101/305011 — genomics — Posted on 2018-04-22

582 gmxapi: a high-level interface for advanced control and extension of molecular dynamics simulations

Irrgang, M. E.; Hays, J. M.; Kasson, P. M.

10.1101/306043 — biophysics — Posted on 2018-04-22

583 Circuit mechanisms for the maintenance and manipulation of information in working memory

Masse, N. Y.; Yang, G. R.; Song, H. F.; Wang, X.-J.; Freedman, D. J.

10.1101/305714 — neuroscience — Posted on 2018-04-22

584 Differential valuation and learning from social and non-social cues in Borderline Personality Disorder

Fineberg, S. K.; Leavitt, J.; Stahl, D. S.; Kronemer, S.; Landry, C.; Alexander-Bloch, A.; Hunt, L.; Corlett, P.

10.1101/305938 — neuroscience — Posted on 2018-04-22

585 Spontaneous behaviors drive multidimensional, brain-wide population activity

Stringer, C.; Pachitariu, M.; Steinmetz, N.; Bai Reddy, C.; Carandini, M.; Harris, K. D.

10.1101/306019 — neuroscience — Posted on 2018-04-22

586 FusoPortal: An interactive repository of hybrid MinION sequenced Fusobacterium genomes improves gene identification and characterization

Sanders, B. E.; Umana, A.; Lemkul, J. A.; Slade, D. J.

10.1101/305607 — microbiology — Posted on 2018-04-22

587 A multidisciplinary approach towards identification of novel antibiotic scaffolds for Acinetobacter baumannii

Bhamidimarri, S. P.; Zahn, M.; Prajapati, J. D.; Schleberger, C.; Soderholm, S.; Hoover, J.; West, J.; Kleinekathoefer, U.; Bumann, D.; Winterhalter, M.; van den Berg, B.

10.1101/306035 — microbiology — Posted on 2018-04-22

588 Discrimination Exposure and DNA Methylation of Stress-Related Genes in Latina Mothers

Santos, H. P.; Nephew, B. C.; Bhattacharya, A.; Tan, X.; Smith, L.; Alyamani, R.; Martin, E. M.; Perreira, K.; Fry, R. C.; Murgatroyd, C.

10.1101/306027 — genomics — Posted on 2018-04-22

589 Multi-model inference of mate choice effects from an information theoretic approach

Carvajal-Rodriguez, A.

10.1101/305730 — evolutionary biology — Posted on 2018-04-22

590 Modelling the emergence of an egalitarian society in the n-player game framework

Tamura, K.; Takikawa, H.

10.1101/305912 — animal behavior and cognition — Posted on 2018-04-22

591 Parkinsons disease and bacteriophages as its overlooked contributors

Tetz, G.; Brown, S.; Hao, Y.; Tetz, V.

10.1101/305896 — microbiology — Posted on 2018-04-22

592 Global Biobank Engine: enabling genotype-phenotype browsing for biobank summary statistics

McInnes, G.; Tanigawa, Y.; DeBoever, C.; Lavertu, A.; Olivieri, J. E.; Aguirre, M.; Rivas, M.

10.1101/304188 — bioinformatics — Posted on 2018-04-22

593 Early candidate biomarkers in urine of Walker-256 lung metastasis rat model.

Wei, J.; Ni, N.; Zhang, L.; Gao, Y.

10.1101/306050 — biochemistry — Posted on 2018-04-22

594 Investigating the relationship between phoneme categorization and reading ability

O'Brien, G. E.; McCloy, D. R.; Kubota, E. C.; Yeatman, J. D.

10.1101/305748 — animal behavior and cognition — Posted on 2018-04-22

595 Aligning interests: Integrating Citizen Science Efforts into Schools Through Service Requirements.

Tsueng, G.; Kumar, A.; Nanis, M.; Su, A. I.

10.1101/304766 — scientific communication and education — Posted on 2018-04-21

596 Sex-specific and conserved gene co-expression networks underlie phenotypes within the paleopolyploid Salvelinus genus (Family Salmonidae)

Sutherland, B. J. G.; Prokkola, J. M.; Audet, C.; Bernatchez, L.

10.1101/305680 — genomics — Posted on 2018-04-21

597 High cholesterol diet modulates macrophage polarization and liver inflammation during early hepatocellular carcinoma progression in zebrafish

De Oliveira, S.; Houseright, R. A.; Graves, A. L.; Golenberg, N.; Korte, B. G.; Miskolci, V.; Huttenlocher, A.

10.1101/299016 — cancer biology — Posted on 2018-04-21

598 IMMUNOMODULATORY ROLE OF KERATIN 76 IN ORAL AND GASTRIC CANCER

Sequeira, I.; Neves, J. F.; Carrero, D.; Peng, Q.; Palasz, N.; Liakath-Ali, K.; Lord, G.; Morgan, P. R.; Lombardi, G.; Watt, F. M.

10.1101/305961 — cancer biology — Posted on 2018-04-21

599 Geminivirus Replication Protein impairs SUMO conjugation of PCNA at two acceptor sites

Arroyo-Mateos, M.; Sabarit, B.; Maio, F.; Sanchez-Duran, M. A.; Rosas-Diaz, T.; Prins, M.; Ruiz-Albert, J.; Luna, A. P.; van der Burg, H. A.; Bejarano, E. R.

10.1101/305789 — plant biology — Posted on 2018-04-21

600 T cell responses to nonstructural protein 3 distinguish infections by Dengue and Zika viruses

Herrera, B. B.; Tsai, W.-Y.; Brites, C.; Luz, E.; Pedroso, C.; Drexler, J. F.; Wang, W.-K.; Kanki, P. J.

10.1101/305839 — microbiology — Posted on 2018-04-21

601 Proteins in the periplasmic space and outer membrane vesicles of Rhizobium etli CE3 grown in minimal medium are largely distinct and change with growth phase

Taboada, H.; Meneses, N.; Dunn, M.; Vargas-Lagunas, C.; Buchs, N.; Castro-Mondragon, J. A.; Heller, M.; Encarnacion, S. M.

10.1101/305797 — microbiology — Posted on 2018-04-21

602 Rbfox1 mediates cell-type-specific splicing in cortical interneurons

Jaglin, X. H.; Wamsley, B.; Favuzzi, E.; Quattracolo, G.; Negro, M.; Yusef, N.; Khodadadi-Jamayran, A.; Rudy, B.; Fishell, G.

10.1101/305904 — neuroscience — Posted on 2018-04-21

603 Sub-2 A Ewald Curvature Corrected Single-Particle Cryo-EM

Tan, Y. Z.; Aiyer, S.; Mietzsch, M.; Hull, J. A.; McKenna, R.; Grieger, J.; Samulski, R. J.; Baker, T. S.; Agbandje-McKenna, M.; Lyumkis, D.

10.1101/305599 — biophysics — Posted on 2018-04-21

604 A double-edged sword: supramolecular complexes of triazavirine display multicenter binding effects which influence aggregate formation

Zabrodskaya, Y. A.; Shvetsov, A. V.; Tsvetkov, V. B.; Egorov, V. V.

10.1101/305615 — biophysics — Posted on 2018-04-21

605 Reproducible genomics analysis pipelines with GNU Guix

Wurmus, R.; Uyar, B.; Osberg, B.; Franke, V.; Gosdschan, A.; Wreczycka, K.; Ronen, J.; Akalin, A.

10.1101/298653 — bioinformatics — Posted on 2018-04-21

606 Integrated systems biology and imaging of the smallest free-living eukaryote Ostreococcus tauri

Smallwood, C. R.; Chen, J.-H.; Kumar, N.; Chrisler, W.; Purvine, S. O.; Kyle, J. E.; Nicora, C. D.; Boudreau, R.; Ekman, A.; Hixson, K. K.; Moore, R. J.; McDermott, G.; Cannon, W. R.; Evans, J. E.

10.1101/293704 — systems biology — Posted on 2018-04-21

607 A protocol for an intercomparison of biodiversity and ecosystem services models using harmonized land-use and climate scenarios

10.1101/300632 — ecology — Posted on 2018-04-21

608 Genomic characterization of six virus-associated cancers identifies changes in the tumor microenvironment and altered genetic programming

Varn, F. S.; Wang, Y.; Cheng, C.

10.1101/289900 — cancer biology — Posted on 2018-04-21

609 Functional analysis of a hypomorphic allele shows that MMP14 catalytic activity is the prime determinant of the Winchester syndrome phenotype

de Vos, I. J. H. M.; Tao, E. Y.; Ong, S. L. M.; Goggi, J. L.; Scerri, T.; Wilson, G. R.; Low, C. G. M.; Wong, A. S. W.; Grussu, D.; Stegmann, A. P. A.; van Geel, M.; Janssen, R.; Amor, D. J.; Bahlo, M.; Dunn, N. R.; Carney, T. J.; Lockhart, P. J.; Coull, B. J.; van Steensel, M. A. M.

10.1101/281485 — genetics — Posted on 2018-04-21

610 Label-free assessment of pre-implantation embryo quality by the Fluorescence Lifetime Imaging Microscopy (FLIM)-phasor approach

Ma, N.; Reyes de Mochel, N.; Pham, P.; Yoo, T.; Cho, K.; Digman, M.

10.1101/286682 — developmental biology — Posted on 2018-04-21

611 Teaching data science fundamentals through realistic synthetic clinical cardiovascular data

Laderas, T.; Vasilevsky, N.; Pederson, B.; Haendel, M.; McWeeney, S.; Dorr, D.

10.1101/232611 — scientific communication and education — Posted on 2018-04-21

612 An important class of intron retention events in human erythroblasts is regulated by cryptic exons proposed to function as splicing decoys

Parra, M.; Booth, B. W.; Weiszmann, R.; Yee, B. A.; Yeo, G. W.; Brown, J. B.; Celniker, S. E.; Conboy, J. G.

10.1101/258897 — molecular biology — Posted on 2018-04-21

613 Recently evolved human-specific methylated regions are enriched in schizophrenia signals

Banerjee, N.; Polushina, T.; Bettella, F.; Giddaluru, S.; Steen, V. M.; Andreassen, O. A.; Hellard, S. L.

10.1101/113175 — genomics — Posted on 2018-04-21

614 The holdase function of Escherichia coli Hsp70 (DnaK) chaperone

Winardhi, R. S.; Tang, Q.; You, H.; Sheetz, M.; Yan, J.

10.1101/305854 — molecular biology — Posted on 2018-04-21

615 CD161 mediates prenatal immune suppression of IFNγ-producing PLZF+ T cells

Halkias, J.; Rackaityte, E.; Aran, D.; Mendoza, V. F.; Eckalbar, W. L.; Burt, T. D.

10.1101/305128 — immunology — Posted on 2018-04-21

616 Interference hypothesis for recombination suppression in chromosomal inversion heterozygotes: A formal genetics analysis in Drosophila melanogaster

Koury, S. A.

10.1101/305490 — genetics — Posted on 2018-04-21

617 Free energy calculations of protein-water complexes with Gromacs

Shahzad, M. A.

10.1101/305037 — biophysics — Posted on 2018-04-21

618 CNV Neurons Are Rare in Aged Human Neocortex

Chronister, W. D.; Wierman, M. B.; Burbulis, I. E.; Wolpert, M. J.; Haakenson, M. F.; Kleinman, J. E.; Hyde, T.; Weinberger, D. R.; Bekiranov, S.; McConnell, M. J.

10.1101/303404 — neuroscience — Posted on 2018-04-21

619 Loop-mediated isothermal amplification assay for Enterococcus sp., E. coli and S. aureus in chicken

Song, H.; Bae, Y.; Kwon, H.; Kwon, Y.; JOH, S.

10.1101/305805 — microbiology — Posted on 2018-04-21

620 Staphylococcal superantigen-like protein 13 activates neutrophils via Formyl Peptide Receptor 2

Zhao, Y.; van Kessel, K. P. M.; de Haas, C. J. C.; Rogers, M. R. C.; van Strijp, J.; Haas, P.-J.

10.1101/305847 — microbiology — Posted on 2018-04-21

621 A Freeloader?: The Highly Eroded Yet Big-Genomed Serratia symbiotica symbiont of Cinara strobi

Manzano-Marin, A.; Coeur d'acier, A.; Clamens, A.-L.; Orvain, C.; Cruaud, C.; Barbe, V.; Jousselin, E.

10.1101/305458 — genomics — Posted on 2018-04-21

622 Comparison of two commercial ELISA kits for detection of rubella specific IgM and IgG antibodies

Viswanathan, R.; George, S.; Murhekar, M. V.; Abraham, A. M.; Singh, M. P.; Jadhav, S.; Nag, V.; Naik, S.; Raut, C. G.; Munivenkatappa, A.; Gupta, M.; Jagtap, V.; Kaduskar, O.; Gupta, N.; Sapkal, G. N.

10.1101/305813 — microbiology — Posted on 2018-04-21

623 Trend and pattern of antimicrobial resistance in molluscan Vibrio species sourced to Canadian estuaries

Banerjee, S. K.; Farber, J.

10.1101/305821 — microbiology — Posted on 2018-04-21

624 Genomic SEM Provides Insights into the Multivariate Genetic Architecture of Complex Traits

Grotzinger, A. D.; Rhemtulla, M.; de Vlaming, R.; Ritchie, S. J.; Mallard, T. T.; Hill, W. D.; Ip, H. F.; McIntosh, A. M.; Deary, I. J.; Koellinger, P. D.; Harden, K. P.; Nivard, M. G.; Tucker-Drob, E. M.

10.1101/305029 — genetics — Posted on 2018-04-21

625 Rethomics: an R framework to analyse high-throughput behavioural data

Geissmann, Q.; Garcia Rodriguez, L.; Beckwith, E. J.; Gilestro, G. F.

10.1101/305664 — bioinformatics — Posted on 2018-04-21

626 Hippocampal synchrony and neocortical desynchrony cooperate to encode and retrieve episodic memories

Griffiths, B. J.; Michelmann, S.; Roux, F.; Chelvarajah, R.; Rollings, D. T.; Sawlani, V.; Hamer, H.; Gollwitzer, S.; Kreiselmeyer, G.; Staresina, B.; Wimber, M.; Hanslmayr, S.

10.1101/305698 — neuroscience — Posted on 2018-04-21

627 Cortical control of kinematic primitives in mice performing a hold-still-center-out reach task

Bollu, T.; Whitehead, S. C.; Prasad, N.; Walker, J. R.; Shyamkumar, N.; Subramaniam, R.; Kardon, B. M.; Cohen, I.; Goldberg, J. H.

10.1101/304907 — neuroscience — Posted on 2018-04-21

628 Instantaneous midbrain control of saccade kinematics

Smalianchuk, I.; Jagadisan, U. K.; Gandhi, N. J.

10.1101/305003 — neuroscience — Posted on 2018-04-21

629 Intrinsic timescales of sensory integration for motion perception

Choi, W.; Paik, S.-B.

10.1101/305409 — neuroscience — Posted on 2018-04-21

630 Determining the Quantitative Principles of T Cell Response to Antigenic Disparity: The Case of Stem Cell Transplant Donor-Recipient Exome Wide Mismatching and HLA Bound Alloreactive Peptides

Salman, A.; Koparde, V.; Hall, C. E.; Jameson-Lee, M.; Roberts, C.; Serrano, M.; AbdulRazzaq, B.; Manjili, M.; Wijesinghe, D.; Hashmi, S.; Buck, G.; Qayyum, R.; Neale, M.; Reed, J.; Toor, A. A.

10.1101/305474 — immunology — Posted on 2018-04-21

631 The closed form of Mad2 is bound to Mad1 and Cdc20 at unattached kinetochores

Zhang, G.; Nilsson, J.

10.1101/305763 — cell biology — Posted on 2018-04-21

632 Precision in a rush: trade-offs between positioning and steepness of the hunchback expression pattern

Tran, H.; Desponds, J.; Perez Romero, C. A.; Coppey, M.; Fradin, C.; Dostatni, N.; Walczak, A. M.

10.1101/305532 — biophysics — Posted on 2018-04-21

633 Disruption of The Psychiatric Risk Gene Ankyrin 3 Enhances Microtubule Dynamics Through GSK3/CRMP2 Signaling

Garza, J. C.; Qi, X.; Gjeluci, K.; Leussis, M. P.; Basu, H.; Reis, S. A.; Zhao, W. N.; Piguel, N. H.; Penzes, P.; Haggarty, S. J.; Martens, G. J.; Poelmans, G.; Petryshen, T. L.

10.1101/303990 — neuroscience — Posted on 2018-04-21

634 SpeciFlex: A Protocol for Mining Binding Site Conformational Selectivity in Structure-Based Inhibitor Discovery

Tonero, M. E.; Kuhn, L. A.

10.1101/304931 — bioinformatics — Posted on 2018-04-21

635 Introduced populations of ragweed show as much evolutionary potential as native populations

McGoey, B. V.; Stinchcombe, J.

10.1101/305540 — evolutionary biology — Posted on 2018-04-21

636 In Silico Analysis Reveals a Shared Immune Signature in CASP8-Mutated Carcinomas with Varying Correlations to Prognosis.

Ghanekar, Y.; Sadasivam, S.

10.1101/305755 — cancer biology — Posted on 2018-04-21

637 DivNet: Estimating diversity in networked communities

Willis, A. D.; Martin, B. D.

10.1101/305045 — bioinformatics — Posted on 2018-04-21

638 Elevated O-GlcNAcylation Enhances Pro-Inflammatory Th17 Function by Altering the Lipid Microenvironment

Machacek, M.; Zhang, Z.; Tan, E. P.; Li, J.; Li, T.; Villar, M. T.; Artigues, A.; Lydic, T.; Slawson, C.; Fields, P.

10.1101/305722 — immunology — Posted on 2018-04-20

639 Dynamics of ion fluxes between neurons, astrocytes and the extracellular space during neurotransmission

Rouach, N.; Dao Duc, K.; Sibille, J.; Holcman, D.

10.1101/305706 — neuroscience — Posted on 2018-04-20

640 Regulatory B cells contribute to the alleviation of colitis induced by Dextran Sulphate Sodium after H.pylori infection

Li, X.; Tan, J.; Zhang, F.; Xue, Q.; Wang, N.; Cong, X.; Wang, J.

10.1101/305094 — immunology — Posted on 2018-04-20

641 Pancreatic islet chromatin accessibility and conformation defines distal enhancer networks of type 2 diabetes risk

Greenwald, W. W.; Chiou, J.; Yan, J.; Qiu, Y.; Dai, N.; Wang, A.; Nariai, N.; Aylward, A.; Han, J. Y.; Kadakia, N.; Barrufet, L.; Okino, M.-L.; Drees, F.; Vinckier, N.; Minichiello, L.; Gorkin, D.; Avruch, J.; Frazer, K.; Sander, M.; Ren, B.; Gaulton, K.

10.1101/299388 — genomics — Posted on 2018-04-20

642 Pan-cancer analysis of transcriptional metabolic dysregulation using The Cancer Genome Atlas

Rosario, S. R.; Long, M. D.; Affronti, H. C.; Rowsam, A. M.; Eng, K. H.; Smiraglia, D. J.

10.1101/295733 — bioinformatics — Posted on 2018-04-20

643 LCA robustly reveals subtle diversity in large-scale single-cell RNA-seq data

Cheng, C.; Easton, J.; Rosencrance, C.; Li, Y.; Ju, B.; Williams, J.; Mulder, H. L.; Chen, W.; Chen, X.

10.1101/305581 — bioinformatics — Posted on 2018-04-20

644 A novel approach to modeling transcriptional heterogeneity identifies the oncogene candidate CBX2 in invasive breast carcinoma

Pique, D.; Montagna, C.; Greally, J.; Mar, J.

10.1101/303396 — systems biology — Posted on 2018-04-20

645 Intratumoral MAPK and PI3K signaling pathway heterogeneity in glioblastoma tissuecorrelates with selective CREB signaling and specific functional gene signatures

Daniel, P.; Filiz, G.; Tymms, M.; Ramsay, R.; Kaye, A. H.; Stylli, S.; Mantamadiotis, T.

10.1101/305052 — pathology — Posted on 2018-04-20

646 Fusobacterium genomics using MinION and Illumina sequencing enables genome completion and correction

Todd, S. M.; Settlage, R. E.; Lahmers, K. K.; Slade, D. J.

10.1101/305573 — microbiology — Posted on 2018-04-20

647 Whole Exome Sequencing in 20,197 Persons for Rare Variants in Alzheimer Disease

10.1101/305631 — genetics — Posted on 2018-04-20

648 Intra-tumor heterogeneity and clonal exclusivity in renal cell carcinoma

Moore, A. L.; Kuipers, J.; Singer, J.; Burcklen, E.; Schraml, P.; Beisel, C.; Moch, H.; Beerenwinkel, N.

10.1101/305623 — cancer biology — Posted on 2018-04-20

649 SoupX removes ambient RNA contamination from droplet based single cell RNA sequencing data

Young, M. D.; Behjati, S.

10.1101/303727 — bioinformatics — Posted on 2018-04-20

650 PRESTO, a new tool for integrating large-scale -omics data and discovering disease-specific signatures

McArdle, S.; Buscher, K.; Ehinger, E.; Pramod, A. B.; Riley, N.; Ley, K.

10.1101/302604 — bioinformatics — Posted on 2018-04-20

651 Self-organised segregation of bacterial chromosomal origins

Murray, S. M.; Sourjik, V.

10.1101/304600 — systems biology — Posted on 2018-04-20

652 Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration

Huck, I.; Gunewardena, S.; Espanol-Suner, R.; Willenbring, H.; Apte, U.

10.1101/304808 — physiology — Posted on 2018-04-20

653 Accurate Nonlinear Mapping between MNI Volumetric and FreeSurfer Surface Coordinate Systems

Wu, J.; Ngo, G. H.; Greve, D.; Li, J.; He, T.; Fischl, B.; Eickhoff, S. B.; Yeo, B. T. T.

10.1101/302794 — neuroscience — Posted on 2018-04-20

654 Persistence of Resident and Transplanted Genotypes of the Undomesticated Yeast, Saccharomyces paradoxus in Forest Soil

Anderson, J. B.; Kasimer, D.; Xia, W.; Shröeder, N. C. H.; Cichowicz, P.; Lioniello, S.; Chakrabarti, R.; Mohan, E.; Kohn, L. M.

10.1101/305060 — ecology — Posted on 2018-04-20

655 Robust predictions of specialized metabolism genes through machine learning

Moore, B. M.; Wang, P.; Fan, P.; Leong, B.; Schenck, C. A.; Lloyd, J. P.; Lehti-Shiu, M.; Last, R.; Pichersky, E.; Shiu, S.-H.

10.1101/304873 — plant biology — Posted on 2018-04-20

656 Nuclear import of Arabidopsis POLY(ADP-RIBOSE) POLYMERASE 2 is mediated by importin-α and a nuclear localization sequence located between the predicted SAP domains

Chen, C.; Lintermann, R.; Wirthmueller, L.

10.1101/304527 — plant biology — Posted on 2018-04-20

657 Generative Adversarial Networks Conditioned on Brain Activity Reconstruct Seen Images

St-Yves, G.; Naselaris, T.

10.1101/304774 — neuroscience — Posted on 2018-04-20

658 Intact memory for local and distal cues in male and female rats that lack adult neurogenesis

Seib, D. R.; Chahley, E.; Princz-Lebel, O.; Snyder, J. S.

10.1101/304733 — neuroscience — Posted on 2018-04-20

659 Reward-related regions form a preferentially coupled system at rest

Huckins, J.; Adeyemo, B.; Miezin, F. M.; Power, J. D.; Gordon, E. M.; Laumann, T. O.; Heatherton, T. F.; Petersen, S. E.; Kelley, W. M.

10.1101/304865 — neuroscience — Posted on 2018-04-20

660 Reverse transcription-PCR using a Primer Set Targeting the 3D Region Detects Foot-and-Mouth Disease Virus with High Sensitivity

Nishi, T.; Kanno, T.; Shimada, N.; Morioka, K.; Yamakawa, M.; Fukai, K.

10.1101/305086 — microbiology — Posted on 2018-04-20

661 Probiotics enhance susceptibility of mice to cryptosporidiosis

Oliveira, B. C. M.; Widmer, G.

10.1101/304956 — microbiology — Posted on 2018-04-20

662 Seed predation increases from the Arctic to the Equator and from high to low elevations

Hargreaves, A.; Suarez, E.; Mehltreter, K.; Myers-Smith, I.; Vanderplank, S. E.; Slinn, H. L.; Vargas-Rodriguez, Y. L.; Haeussler, S.; David, S.; Munoz, J.; Almazan-Nunoz, R. C.; Loughnan, D.; Benning, J. W.; Moeller, D. A.; Brodie, J. F.; Thomas, H. J.; Morales M, P. A.

10.1101/304634 — ecology — Posted on 2018-04-20

663 Early life factors influencing hand preference in the UK biobank cohort

de Kovel, C. G. F.; Carrion-Castillo, A.; Francks, C.

10.1101/305425 — developmental biology — Posted on 2018-04-20

664 PRY-1/Axin signaling regulates lipid metabolism in Caenorhabditis elegans

Ranawade, A.; Mallick, A.; Gupta, B. P.

10.1101/289462 — physiology — Posted on 2018-04-20

665 Overlapping neural processes for stopping and economic choice in orbitofrontal cortex

balasubramani, p. p.; Hayden, B.

10.1101/304709 — neuroscience — Posted on 2018-04-20

666 Changes in neuronal immunofluorescence in the C- versus N-terminal domains of hnRNP H following D1 dopamine receptor activation

Ruan, Q. T.; Yazdani, N.; Beierle, J. A.; Hixson, K. M.; Hokenson, K. E.; Apicco, D. J.; Luttik, K.; Zheng, K.; Ash, P. E.; Szumlinski, K.; Russek, S.; Wolozin, B.; Bryant, C. D.

10.1101/305565 — neuroscience — Posted on 2018-04-20

667 Development of the P300 from childhood to adulthood: a multimodal EEG and MRI study

Overbye, K.; Huster, R. J.; Walhovd, K. B.; Fjell, A. M.; Tamnes, C. K.

10.1101/304832 — neuroscience — Posted on 2018-04-20

668 Prader-Willi locus Snord116 RNA processing requires an active endogenous allele and neuron-specific splicing by Rbfox3/NeuN

Coulson, R. L.; Powell, W. T.; Yasui, D. H.; Dileep, G.; Resnick, J.; LaSalle, J. M.

10.1101/305557 — molecular biology — Posted on 2018-04-20

669 Implicit but not explicit exposure to threat conditioned stimulus prevents spontaneous recovery of threat potentiated startle responses in humans

Oyarzun, J. P.; Camara, E.; Kouider, S.; Fuentemilla, L.; de Diego-Balaguer, R.

10.1101/304592 — animal behavior and cognition — Posted on 2018-04-20

670 Predicting the time needed to conduct an environmental systematic review or systematic map: analysis and decision support tool

Haddaway, N. R.; Westgate, M.

10.1101/303073 — scientific communication and education — Posted on 2018-04-20

671 Animacy and real world size shape object representations in the human medial temporal lobes

Blumenthal, A.; Stojanoski, B.; Martin, C.; Cusack, R.; Kohler, S.

10.1101/304824 — neuroscience — Posted on 2018-04-20

672 3 minutes to precisely measure morphogen concentration

Lucas, T.; Tran, H.; Perez Romero, C. A.; Guillou, A.; Fradin, C.; Coppey, M.; Walczak, A. M.; Dostatni, N.

10.1101/305516 — developmental biology — Posted on 2018-04-20

673 In vivo Chemical Reprogramming of Astrocytes into Functional Neurons

Ma, Y.; Xie, H.; Du, X.; Wang, L.; Jin, X.; Sun, S.; Han, Y.; Han, Y.; Xu, J.; Huang, Z.; Chai, Z.; Deng, H.

10.1101/305185 — cell biology — Posted on 2018-04-20

674 CXXC1 is redundant for normal DNA double-strand break formation and meiotic recombination in mouse

Tian, H.; Billings, T.; Petkov, P. M.

10.1101/305508 — cell biology — Posted on 2018-04-20

675 Dissecting bacterial resistance and resilience in antibiotic responses

Meredith, H. R.; Andreani, V.; Lopatkin, A. J.; Lee, A. J.; Anderson, D. J.; Batt, G.; You, L.

10.1101/305482 — cell biology — Posted on 2018-04-20

676 Benchmarking Statistical Multiple Sequence Alignment

Nute, M. G.; Saleh, E.; Warnow, T.

10.1101/304659 — bioinformatics — Posted on 2018-04-20

677 USP7 couples DNA replication termination to mitotic entry.

Galarreta, A.; Lecona, E.; Valledor, P.; Ubieto, P.; Lafarga, V.; Specks, J.; Fernandez-Capetillo, O.

10.1101/305318 — cell biology — Posted on 2018-04-20

678 Live-cell imaging of marked chromosome regions reveals dynamics of mitotic chromosome resolution and compaction

Eykelenboom, J. K.; Gierlinski, M.; Yue, Z.; Hegarat, N.; Pollard, H.; Fukagawa, T.; Hochegger, H.; Tanaka, T. U.

10.1101/305391 — cell biology — Posted on 2018-04-20

679 Cluster Tendency Assessment in Neuronal Spike Data

Mahallati, S.; Bezdek, J. C.; Popovic, M. R.; Valiante, T. A.

10.1101/285064 — neuroscience — Posted on 2018-04-20

680 Early detection of active Human Cytomegalovirus infection after living-donor liver transplantation

Rizk, M. A.; Agha, S. A. E.; Zaki, M. E. S.; El-Mashad, N. B. E.-D.; El-Saadany, M. M. F.

10.1101/304360 — microbiology — Posted on 2018-04-20

681 Population genetics of Paramecium mitochondrial genomes: recombination, mutation spectrum, and efficacy of selection.

Johri, P.; Marinov, G.; Doak, T. G.; Lynch, M.

10.1101/281865 — evolutionary biology — Posted on 2018-04-20

682 A Single-Cell Atlas of Cell Types, States, and Other Transcriptional Patterns from Nine Regions of the Adult Mouse Brain

Saunders, A.; Macosko, E.; Wysoker, A.; Goldman, M.; Krienen, F.; de Rivera, H.; Bien, E.; Baum, M.; Wang, S.; Goeva, A.; Nemesh, J.; Kamitaki, N.; Brumbaugh, S.; Kulp, D.; McCarroll, S. A.

10.1101/299081 — neuroscience — Posted on 2018-04-20

683 Frequencies of circulating Th1-biased T follicular helper cells in acute HIV-1 infection correlate with the development of HIV-specific antibody responses and lower set point viral load

Baiyegunhi, O.; Ndlovu, B.; Ogunshola, F.; Ismail, N.; Walker, B. D.; Ndung'u, T.; Ndhlovu, Z. M.

10.1101/304329 — immunology — Posted on 2018-04-20

684 Tigmint: Correcting Assembly Errors Using Linked Reads From Large Molecules

Jackman, S. D.; Coombe, L.; Chu, J.; Warren, R. L.; Vandervalk, B. P.; Yeo, S.; Xue, Z.; Mohamadi, H.; Bohlmann, J.; Jones, S. J.; Birol, I.

10.1101/304253 — genomics — Posted on 2018-04-20

685 Unifying mutualism diversity for interpretation and prediction

Wu, F.; Lopatkin, A.; Needs, D.; Lee, C.; Mukherjee, S.; You, L.

10.1101/304295 — systems biology — Posted on 2018-04-20

686 Mitotic chromosomes fold by condensin-dependent helical winding of chromatin loop arrays

Gibcus, J. H.; Samejima, K.; Goloborodko, A.; Samejima, I.; Naumova, N.; Kanemaki, M.; Xie, L.; Paulson, J. R.; Earnshaw, W. C.; Mirny, L. A.; Dekker, J.

10.1101/174649 — genomics — Posted on 2018-04-20

687 Gaining insights from RNA-Seq data using iDEP

Ge, S. X.; Son, E. W.

10.1101/148411 — bioinformatics — Posted on 2018-04-20

688 Behavioral and neural representations of spatial directions across words, schemas, and images

Weisberg, S. M.; Marchette, S. A.; Chatterjee, A.

10.1101/220137 — neuroscience — Posted on 2018-04-20

689 Dynamics of pellet fragmentation and aggregation in liquid-grown cultures of Streptomyces lividans

Zacchetti, B.; Smits, P.; Claessen, D.

10.1101/270595 — microbiology — Posted on 2018-04-20

690 Phylogenetic Comparative Methods on Phylogenetic Networks with Reticulations

Bastide, P.; Solis-Lemus, C.; Kriebel, R.; Sparks, K. W.; Ane, C.

10.1101/194050 — evolutionary biology — Posted on 2018-04-20

691 Persistent coding of outcome-predictive cue features in the rat nucleus accumbens

Gmaz, J. M.; Carmichael, J. E.; van der Meer, M.

10.1101/300251 — neuroscience — Posted on 2018-04-20

692 Direct RNA Sequencing of the Complete Influenza A Virus Genome

Keller, M. W.; Rambo-Martin, B. L.; Wilson, M. M.; Ridenour, C. A.; Shepard, S. S.; Stark, T. J.; Neuhaus, E. B.; Dugan, V. G.; Wentworth, D. E.; Barnes, J. R.

10.1101/300384 — genomics — Posted on 2018-04-20

693 Accurate detection of convergent amino-acid evolution with PCOC

Rey, C.; Gueguen, L.; Semon, M.; Boussau, B.

10.1101/247296 — evolutionary biology — Posted on 2018-04-20

694 A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumours

Redford, L.; Alhilal, G.; Needham, S.; O'Brien, O.; Coaker, J.; Tyson, J.; Amorim, L. M.; Middleton, I.; Sheth, H.; Izuogu, O.; Arends, M.; Oniscu, A.; Alonso, A. M.; Laguna, S. M.; Santibanez-Koref, M.; Jackson, M. S.; Burn, J.

10.1101/305383 — genomics — Posted on 2018-04-20

695 DNA profiling reveals Neobenedenia girellae as the primary culprit in global fisheries and aquaculture

Brazenor, A. K.; Bertozzi, T.; Miller, T. L.; Whittington, I. D.; Hutson, K. S.

10.1101/304261 — genetics — Posted on 2018-04-20

696 Motor nuclei innervating eye muscles spared in mouse model of SOD1-linked ALS

Thomas, E. V.; Nagy, M.; Fenton, W. A.; Horwich, A. L.

10.1101/304857 — neuroscience — Posted on 2018-04-20

697 Impact of DNA sequencing and analysis methods on 16S rRNA gene bacterial community analysis in dairy products

Xue, Z.; Kable, M. E.; Marco, M. L.

10.1101/305078 — microbiology — Posted on 2018-04-20

698 Cis- and Trans-Acting Expression Quantitative Trait Loci Differentially Regulate Gamma-Globin Gene Expression

Shaikho, E. M.; Farrell, J. J.; Sebastiani, P.; Chui, D. H. K.; Steinberg, M. H.

10.1101/304899 — genetics — Posted on 2018-04-20

699 Relative evolutionary rates in proteins are largely insensitive to the substitution model

Spielman, S. J.; Kosakovsky Pond, S. L.

10.1101/304758 — evolutionary biology — Posted on 2018-04-20

700 Investigating the combined association of BMI and alcohol consumption on liver disease and biomarkers: a Mendelian randomization study of over 90 000 adults from the Copenhagen General Population Study

Carter, A. R.; Borges, M.-C.; Benn, M.; Tybjarg-Hansen, A.; Smith, G. D.; Nordestgaard, B. G.; Lawlor, D. A.

10.1101/303313 — epidemiology — Posted on 2018-04-20

701 Testing the causal effects between subjective wellbeing and physical health using Mendelian randomisation

Wootton, R. E.; Lawn, R. B.; Millard, L. A. C.; Davies, N. M.; Taylor, A. E.; Munafo, M. R.; Timpson, N. J.; Davis, O. S. P.; Davey Smith, G.; Haworth, C. M. A.

10.1101/304741 — epidemiology — Posted on 2018-04-20

702 Characterisation and functional predictions of canine long non-coding RNAs

Le Beguec, C.; Wucher, V.; Lagoutte, L.; Cadieu, E.; Botherel, N.; Hedan, B.; De Brito, C.; Guillory, A.-S.; Andre, C.; Derrien, T.; Hitte, C.

10.1101/303966 — genomics — Posted on 2018-04-20

703 Extraordinary genome instability and widespread chromosome rearrangements during vegetative growth

Stukenbrock, E. H.; Möller, M.; Habig, M.; Freitag, M.

10.1101/304915 — genomics — Posted on 2018-04-20

704 Biphasic recruitment of TRF2 to DNA damage sites promotes non-sister chromatid homologous recombination repair

Kong, X.; Cruz, G.; Trinh, S.; Zhu, X.-D.; Berns, M.; Yokomori, K.

10.1101/305169 — cell biology — Posted on 2018-04-20

705 EGF signalling in epithelial carcinoma cells utilizes preformed receptor homoclusters, with larger heteroclusters post activation

Fournier, C.; Wollman, A.; Llorente-Garcia, I.; Harriman, O.; Ouarat, D.; Wilding, J.; Bodmer, W.; Leake, M. C.

10.1101/305292 — biophysics — Posted on 2018-04-20

706 Repurposing covalent EGFR/HER2 inhibitors for on-target degradation of human Tribbles 2 (TRIB2) pseudokinase

Foulkes, D. M.; Byrne, D. P.; Bailey, F. P.; Ferries, S.; Eyers, C.; Keeshan, K.; Shrestha, S.; Yeung, W.; Kannan, N.; Wells, C.; Drewry, D. H.; Zuercher, W. J.; Eyers, P.

10.1101/305243 — biochemistry — Posted on 2018-04-20

707 Destabilization of Ran C-terminus promotes GTP loading and occurs in multiple Ran cancer mutations

Sun, Q.; Zhang, Y.; Zhou, J.; Tan, Y.; Zhou, Q.; Tong, A.-P.; Shen, X.; Jia, D.; Sun, X.

10.1101/305177 — biochemistry — Posted on 2018-04-20

708 Hematopoietic Stem Cell Dynamics are Regulated by Progenitor Demand: Lessons from a Quantitative Modeling Approach

Klose, M.; Florian, M. C.; Geiger, H.; Glauche, I.

10.1101/305367 — systems biology — Posted on 2018-04-20

709 Maturing Mycobacterial Peptidoglycan Requires Non-canonical Crosslinks to Maintain Shape

Baranowski, C.; Sham, L.-T.; Eskandarian, H. A.; Welsh, M. A.; Lim, H. C.; Kieser, K. J.; Wagner, J. C.; Walker, S.; McKinney, J. D.; Fantner, G. E.; Ioerger, T. R.; Bernhardt, T. G.; Rubin, E. J.; Rego, E. H.

10.1101/291823 — microbiology — Posted on 2018-04-20

710 Possibilities for improvement of humoral innate immunity in turkeys and hens in conditions of thermal stress by the immunomodulator Immunobeta

Bozakova, N.; Sotirov, L.; Denev, S.; Koynarski, T.

10.1101/305300 — immunology — Posted on 2018-04-20

711 Preliminary study on the application of PspA as carrier

Wang, L.; Tan, Y.; Wei, C.; Zhang, H.; Luo, P.; Ma, X.; Zhang, S.

10.1101/305102 — immunology — Posted on 2018-04-20

712 On the relationship between high-order linkage disequilibrium and epistasis

Zan, Y.; Forsberg, S.; Carlborg, O.

10.1101/305342 — genetics — Posted on 2018-04-20

713 Inference of significant microbial interactions from longitudinal metagenomics sequencing data

Gao, X.; Huynh, B.-T.; Guillemot, D.; Glaser, P.; Opatowski, L.

10.1101/305326 — ecology — Posted on 2018-04-20

714 CHOP: Haplotype-aware path indexing in population graphs

Mokveld, T. O.; Linthorst, J.; Al-Ars, Z.; Reinders, M.

10.1101/305268 — bioinformatics — Posted on 2018-04-20

715 Single-Dose Monocrotaline Pyrrole Injection as a Model of Pulmonary Endothelial Injury In Mice

Raoul, W.; Hulin, A.; Saber, G.; Boisnier, C.; Eddahibi, S.; Adnot, S.; Maitre, B.

10.1101/305235 — physiology — Posted on 2018-04-20

716 Interferon lambda 4 impacts broadly on hepatitis C virus diversity.

Ansari, M. A.; Aranday-Cortes, E.; Ip, C. L.; da Silva Filipe, A.; Hin, L. S.; Bamford, C. G. G.; Bonsall, D.; Trebes, A.; Piazza, P.; Sreenu, V.; Cowton, V. M.; STOP-HCV Consortium, ; Hudson, E.; Bowden, R.; Patel, A. H.; Foster, G. R.; Irving, W. L.; Agarwal, K.; Thomson, E. C.; Simmonds, P.; Klenerman, P.; Holmes, C.; Barnes, E.; Spencer, C. C.; McLauchlan, J.; Pedergnana, V.

10.1101/305151 — genomics — Posted on 2018-04-20

717 Replicative cellular age distributions in compartmentalised tissues

Boettcher, M. A.; Werner, B.; Dingli, D.; Traulsen, A.

10.1101/305250 — evolutionary biology — Posted on 2018-04-20

718 In silico analysis of piRNAs in retina reveals potential targets in intracellular transport and retinal degeneration

Sivagurunathan, S.; Srikakulam, N.; Arunachalam, J. P.; Pandi, G.; Chidambaram, S.

10.1101/305144 — cell biology — Posted on 2018-04-20

719 Partially methylated domains are hypervariable in breast cancer and fuel widespread CpG island hypermethylation

Brinkman, A. B.; Nik-Zainal, S.; Simmer, F.; Rodriguez-Gonzalez, F. G.; Smid, M.; Alexandrov, L. B.; Butler, A.; Martin, S.; Davies, H.; Dominik, G.; Zou, X.; Ramakrishna, M.; Staaf, J.; Ringner, M.; Sieuwerts, A.; Ferrari, A.; Morganella, S.; Thomas, F.; Kristensen, V.; Gut, M.; van de Vijver, M. J.; Borresen-Dale, A.-L.; Richardson, A. L.; Thomas, G.; Gut, I. G.; Martens, J. W. M.; Foekens, J. A.; Stratton, M.; Stunnenberg, H. G.

10.1101/305193 — cancer biology — Posted on 2018-04-20

720 The Amyloid Precursor-like Protein APL-1 Regulates Axon Regeneration

Zeng, L.; El Bejjani, R.; Hammarlund, M.

10.1101/305284 — neuroscience — Posted on 2018-04-20

721 No evidence of functional co-adaptation between clustered microRNAs

Marco, A.

10.1101/274811 — evolutionary biology — Posted on 2018-04-20

722 The Drosophila TNF Eiger activates caspase-dependent necrosis when apoptosis is blocked

Li, M.; Fan, Y.

10.1101/304964 — developmental biology — Posted on 2018-04-20

723 Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats

Schmid, M.; Frei, D.; Patrignani, A.; Schlapbach, R.; Frey, J. E.; Remus-Emsermann, M. N. P.; Ahrens, C. H.

10.1101/300186 — genomics — Posted on 2018-04-20

724 VULCAN: Network Analysis of ER-α activation reveals reprogramming of GRHL2

Holding, A. N.; Giorgi, F. M.; Donnelly, A.; Cullen, A. E.; Selth, L. A.; Markowetz, F.

10.1101/266908 — cancer biology — Posted on 2018-04-20

725 Container-based bioinformatics with Pachyderm

Novella, J. A.; Emami Khoonsari, P.; Herman, S.; Whitenack, D.; Capuccini, M.; Burman, J.; Kultima, K.; Spjuth, O.

10.1101/299032 — bioinformatics — Posted on 2018-04-20

726 REMAP: An online remote sensing application for land cover classification and monitoring

Murray, N. J.; Keith, D. A.; Simpson, D.; Wilshire, J. H.; Lucas, R. M.

10.1101/212464 — ecology — Posted on 2018-04-20

727 Coupling of autonomic and central events during sleep benefits declarative memory consolidation

Naji, M.; Krishnan, G.; McDevitt, E. A.; Bazhenov, M.; Mednick, S. C.

10.1101/195586 — neuroscience — Posted on 2018-04-20

728 Determining protein structures using genetics

Schmiedel, J.; Lehner, B.

10.1101/303875 — systems biology — Posted on 2018-04-20

729 Yap regulates glucose utilization and sustains nucleotide synthesis to enable organ growth

Cox, A.; Tsomides, A.; Yimlamai, D.; Hwang, K.; Miesfeld, J.; Galli, G.; Fowl, B.; Fort, M.; Ma, K.; Sullivan, M.; Hosios, A.; Snay, E.; Yuan, M.; Brown, K.; Lien, E.; Chhangawala, S.; Steinhauser, M.; Asara, J.; Houvras, Y.; Link, B.; Vander Heiden, M.; Camargo, F.; Goessling, W.

10.1101/300053 — developmental biology — Posted on 2018-04-19

730 Cluster Tendency Assessment in Neuronal Spike Data

Mahallati, S.; Bezdek, J. C.; Popovic, M. R.; Valiante, T.

10.1101/285064 — neuroscience — Posted on 2018-04-19

731 Genetic studies of accelerometer-based sleep measures in 85,670 individuals yield new insights into human sleep behaviour

Jones, S. E.; van Hees, V. T.; Mazzotti, D. R.; Marques-Vidal, P.; Sabia, S.; van der Spek, A.; Dashti, H. S.; Engmann, J.; Kocevska, D.; Tyrrell, J.; Beaumont, R. N.; Hillsdon, M.; Ruth, K. S.; Tuke, M. A.; Yaghootkar, H.; Sharp, S.; Jie, Y.; Harrison, J. W.; Freathy, R. M.; Murray, A.; Luik, A. I.; Amin, N.; Lane, J. M.; Saxena, R.; Rutter, M. K.; Tiemeier, H.; Kutalik, Z.; Kumari, M.; Frayling, T. M.; Weedon, M. N.; Gehrman, P.; Wood, A. R.

10.1101/303925 — genetics — Posted on 2018-04-19

732 RefSeq database growth influences the accuracy of k-mer-based species identification

Nasko, D. J.; Koren, S.; Phillippy, A. M.; Treangen, T. J.

10.1101/304972 — bioinformatics — Posted on 2018-04-19

733 Genome-wide association analyses of chronotype in 697,828 individuals provides new insights into circadian rhythms in humans and links to disease

Jones, S. E.; Lane, J. M.; Wood, A. R.; van Hees, V. T.; Tyrrell, J.; Beaumont, R. N.; Jeffries, A. R.; Dashti, H. S.; Hillsdon, M.; Ruth, K. S.; Tuke, M. A.; Yagohootkar, H.; Sharp, S. A.; Ji, Y.; Harrison, J. W.; Dawes, A.; Byrne, E. M.; Tiemeier, H.; Allebrandt, K. V.; Bowden, J.; Ray, D. W.; Freathy, R. M.; Murray, A.; Mazzotti, D. R.; Gehrman, P. R.; 23andMe Research Team, ; Lawlor, D. A.; Frayling, T. M.; Rutter, M. K.; Hinds, D. A.; Saxena, R.; Weedon, M. N.

10.1101/303941 — genetics — Posted on 2018-04-19

734 GWAS in 446,118 European adults identifies 78 genetic loci for self-reported habitual sleep duration supported by accelerometer-derived estimates

Dashti, H.; Jones, S. E.; Wood, A. R.; Lane, J.; van Hees, V. T.; Wang, H.; Rhodes, J. A.; Song, Y.; Patel, K.; Anderson, S. G.; Beaumont, R. N.; Bechtold, D. A.; Bowden, J.; Cade, B. E.; Garaulet, M.; Kyle, S. D.; Little, M. A.; Loudon, A. S.; Luik, A. I.; Scheer, F. A.; Spiegelhalder, K.; Tyrrell, J.; Gottlieb, D. J.; Tiemeier, H.; Ray, D. W.; Purcell, S. M.; Frayling, T. M.; Redline, S.; Lawlor, D. A.; Rutter, M. K.; Weedon, M. N.; Saxena, R.

10.1101/274977 — genetics — Posted on 2018-04-19

735 Neuromesodermal Progenitors are a Conserved Source of Spinal Cord with Divergent Growth Dynamics

Attardi, A.; Fulton, T.; Florescu, M.; Shah, G.; Muresan, L.; Huisken, J.; van Oudenaarden, A.; Steventon, B.

10.1101/304543 — developmental biology — Posted on 2018-04-19

736 Particle-templated emulsification for microfluidics-free digital biology

Hatori, M. N.; Kim, S. C.; Abate, A. R.

10.1101/304923 — bioengineering — Posted on 2018-04-19

737 Transient kinetic analysis of SWR1C-catalyzed H2A.Z deposition unravels the impact of nucleosome dynamics and the asymmetry of stepwise histone exchange

Singh, R. K.; Watanabe, S.; Bilsel, O.; Peterson, C. L.

10.1101/304998 — biochemistry — Posted on 2018-04-19

738 Glycoprotein 3 of porcine reproductive and respiratory syndrome virus exhibits an unusual hairpin-like membrane topology

Zhang, M.; Krabben, L.; Wang, F.; Veit, M.

10.1101/304337 — biochemistry — Posted on 2018-04-19

739 High-dimensional single-cell cartography reveals novel skeletal muscle resident cell populations

Giordani, L.; He, G. J.; Negroni, E.; Sakai, H.; Law, J. Y.; Siu, M. M.; Wan, R.; Tajbakhsh, S.; Cheung, T. H.; Le Grand, F.

10.1101/304683 — cell biology — Posted on 2018-04-19

740 Tight Turns of Outer Membrane Proteins: An Analysis of Sequence, Structure, and Hydrogen Bonding

Franklin, M.; Slusky, J.

10.1101/304287 — biophysics — Posted on 2018-04-19

741 A kinetic model for fluorescence microscopy experiments in disordered media that contains binding sites and obstacles

Shkilev, V. P.

10.1101/302422 — biophysics — Posted on 2018-04-19

742 Improved single-molecule localization precision in astigmatism-based 3D superresolution imaging using weighted likelihood estimation

Bohrer, C. H.; Yang, X.; Lyu, Z.; Wang, S.-C.; Xiao, J.

10.1101/304816 — biophysics — Posted on 2018-04-19

743 Geometry-dependent instabilities in electrically excitable tissues

McNamara, H. M.; Dodson, S.; Huang, Y.-L.; Miller, E. W.; Sandstede, B.; Cohen, A. E.

10.1101/291617 — biophysics — Posted on 2018-04-19

744 Stepwise C-Terminal Truncation of Cardiac Troponin T Alters Function at Low and Saturating Ca2+

Johnson, D.; Angus, C. W.; Chalovich, J. M.

10.1101/304642 — biochemistry — Posted on 2018-04-19

745 The Hippo pathway effector Taz is required for cell fate specification and fertilization in zebrafish

Dingare, C.; Niedzwetzki, A.; Klemmt, P. A.; Godbersen, S.; Fuentes, R.; Mullins, M. C.; Lecaudey, V.

10.1101/304626 — developmental biology — Posted on 2018-04-19

746 The alkyl side chain of PACA nanoparticles dictates the impact on cellular stress responses and the mode of particle-induced cell death

Szwed, M.; Soenstevold, T.; Oeverbye, A.; Engedal, N.; Grallert, B.; Moerch, Y. A.; Iversen, T.-G.; Skotland, T.; Sandvig, K.; Torgersen, M. L.

10.1101/304618 — cell biology — Posted on 2018-04-19

747 Real Time de novo Deposition of Centromeric Histone-associated Proteins Using the Auxin Inducible Degradation System

Hoffmann, S.; Fachinetti, D.

10.1101/304725 — cell biology — Posted on 2018-04-19

748 High quality whole genome sequence of an abundant Holarctic odontocete, the harbour porpoise (Phocoena phocoena)

Autenrieth, M.; Hartmann, S.; Lah, L.; Roos, A.; Dennis, A.; Tiedemann, R.

10.1101/246173 — genomics — Posted on 2018-04-19

749 Binge-like Acquisition of α-pyrrolidinopentiophenone (α-PVP) Self-Administration in Female Rats

Javadi-Paydar, M.; Harvey, E. L.; Grant, Y.; Vandewater, S. A.; Creehan, K. M.; Nguyen, J. D.; Dickerson, T. J.; Taffe, M. A.

10.1101/191155 — neuroscience — Posted on 2018-04-19

750 Effect of Infection with, and Treatment of, Sensitive and Resistant Strains of Teladorsagia Circumcincta on the Ovine Intestinal Microbiota

Watkins, C. A.; Bartley, D. J.; Ergün, B. G.; Yildizhan, B.; Ross-Watt, T.; Morrison, A. A.; Sanmartin, M. J. R.; Strathdee, F.; Andrews, L.; Free, A.

10.1101/304386 — microbiology — Posted on 2018-04-19

751 Swarmer cell development of the bacterium Proteus mirabilis requires the conserved ECA biosynthesis gene, rffG

Little, K.; Tipping, M. J.; Gibbs, K. A.

10.1101/198622 — microbiology — Posted on 2018-04-19

752 Sorting Nexin 27 (SNX27): A Novel Regulator of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Trafficking

McDermott, M. I.; Thelin, W. R.; Chen, Y.; Lyons, P. T.; Reilly, G.; Gentzsch, M.; Lei, C.; Hong, W.; Stutts, M. J.; Playford, M. P.; Bankaitis, V. A.

10.1101/304717 — cell biology — Posted on 2018-04-19

753 De novo organelle biogenesis in the cyanobacterium TDX16 released from the green alga Haematococcus pluvialis

Dong, Q.-l.; Xing, X.-y.; Han, Y.; Wei, X.-l.; Zhang, S.

10.1101/161463 — cell biology — Posted on 2018-04-19

754 Recentrifuge: robust comparative analysis and contamination removal for metagenomic data

Marti, J. M.

10.1101/190934 — bioinformatics — Posted on 2018-04-19

755 Project Dhaka: Variational Autoencoder for Unmasking Tumor Heterogeneity from Single Cell Genomic Data

Rashid, S.; Shah, S.; Bar-Joseph, Z.; Pandya, R.

10.1101/183863 — genomics — Posted on 2018-04-19

756 GeNets: A unified web platform for network-based analyses of genomic data

Li, T.; Kim, A.; Rosenbluh, J.; Horn, H.; Greenfeld, L.; An, D.; Zimmer, A.; Liberzon, A.; Bistline, J.; Natoli, T.; Li, Y.; Tsherniak, A.; Narayan, R.; Subramanian, A.; Liefeld, T.; Wong, B.; Thompson, D.; Calvo, S.; Carr, S.; Boehm, J.; Jaffe, J.; Mesirov, J.; Hacohen, N.; Regev, A.; Lage, K.

10.1101/196303 — genomics — Posted on 2018-04-19

757 Regulation of cyclic electron flow by chloroplast NADPH-dependent thioredoxin system

Nikkanen, L.; Toivola, J.; Trotta, A.; Guinea Diaz, M.; Tikkanen, M.; Aro, E.-M.; Rintamaki, E.

10.1101/261560 — plant biology — Posted on 2018-04-19

758 Quantifying nucleation in vivo reveals the physical basis of prion-like phase behavior

Khan, T.; Kandola, T.; Wu, J.; Ketter, E.; Venkatesan, S.; Lange, J. J.; Rodriguez Gama, A.; Box, A.; Unruh, J. R.; Cook, M.; Halfmann, R.

10.1101/205690 — biophysics — Posted on 2018-04-19

759 Compendium of Synovial Signatures Identifies Pathologic Characteristics for Predicting Treatment Response in Rheumatoid Arthritis

Kim, K.-J.; Kim, M.; Tagkopoulos, I.

10.1101/279786 — bioinformatics — Posted on 2018-04-19

760 Linking drug target and pathway activation for effective therapy using multi-task learning

Yang, M.; Simm, J.; Lam, C. C.; Zakeri, P.; van Westen, G. J. P.; Moreau, Y.; Saez-Rodriguez, J.

10.1101/225573 — bioinformatics — Posted on 2018-04-19

761 Sex-specific changes in the aphid DNA methylation landscape

Mathers, T. C.; Mugford, S. T.; Percival-Alwyn, L.; Chen, Y.; Kaithakottil, G.; Swarbreck, D.; Hogenhout, S. A.; van Oosterhout, C.

10.1101/286302 — genomics — Posted on 2018-04-19

762 The Healthy Pregnancy Research Program: Transforming Pregnancy Research Through a ResearchKit App

Radin, J. M.; Steinhubl, S. R.; Su, A. I.; Bhargava, H.; Greenberg, B.; Bot, B. M.; Doerr, M.; Topol, E. J.

10.1101/289371 — epidemiology — Posted on 2018-04-19

763 Dynamic and causal contribution of parietal cortex to perceptual decisions during category learning

Zhong, L.; Zhang, Y.; Duan, C. A.; Pan, J.; Xu, N.

10.1101/304071 — neuroscience — Posted on 2018-04-19

764 Adaptation to local climate in a multi-trait space: evidence from silver fir (Abies alba Mill.) populations across a heterogeneous environment

Csillery, K.; Ovaskainen, O.; Sperisen, C.; Widmer, A.; Gugerli, F.

10.1101/292540 — evolutionary biology — Posted on 2018-04-19

765 The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology

Meehan, C. J.; Moris, P.; Kohl, T. A.; Pecerska, J.; Akter, S.; Merker, M.; Utpatel, C.; Beckert, P.; Gehre, F.; Lempens, P.; Stadler, T.; Kaswa, M. K.; Kuhnert, D.; Niemann, S.; de Jong, B. C.

10.1101/302232 — epidemiology — Posted on 2018-04-19

766 The latency of a visual evoked potential tracks the onset of decision making

Nunez, M. D.; Gosai, A.; Vandekerckhove, J.; Srinivasan, R.

10.1101/275727 — neuroscience — Posted on 2018-04-19

767 Human cytomegalovirus tropism modulator UL148 interacts with SEL1L, a cellular factor that governs ER-associated degradation of the viral envelope glycoprotein, gO

Nguyen, C.; Siddiquey, M. N. A.; Zhang, H.; Kamil, J. P.

10.1101/304394 — microbiology — Posted on 2018-04-19

768 Foliar pathogens are unlikely to stabilize coexistence of competing species in a California grassland

Spear, E. R.; Mordecai, E. A.

10.1101/226928 — ecology — Posted on 2018-04-19

769 Co-existing feedback loops generate tissue-specific circadian rhythms

Pett, J. P.; Kondoff, M.; Bordyugov, G.; Kramer, A.; Herzel, H.

10.1101/304451 — systems biology — Posted on 2018-04-19

770 Functional connectivity alterations in Parkinson’s disease during the stop-signal task

Vriend, C.; Leffa, D.; Trujillo, J.; Gerrits, N.; de Boer, F.; Berendse, H.; van der Werf, Y. D.; van den Heuvel, O. A.

10.1101/304584 — neuroscience — Posted on 2018-04-19

771 Analysing disturbance response of cell-to-cell communication systems: a case study for activator-repressor-diffuser motif

Kotsuka, T.; Hori, Y.

10.1101/304436 — synthetic biology — Posted on 2018-04-19

772 Unilateral movement preparation causes task-specific modulation of TMS responses in the passive, opposite limb.

Chye, L.; Riek, S.; de Rugy, A.; Carson, R. G.; Carroll, T. J.

10.1101/304410 — neuroscience — Posted on 2018-04-19

773 Tinnitus development is associated with synaptopathy of inner hair cells in Mongolian gerbils

Forster, J.; Wendler, O.; Buchheidt-Doerfler, I.; Krauss, P.; Schilling, A.; Sterna, E.; Schulze, H.; Tziridis, K.

10.1101/304576 — neuroscience — Posted on 2018-04-19

774 Reappraising the human mitochondrial DNA recombination dogma

Perera, S.; Ramos, A.; Alvarez, L.; Jurado, D.; Guardiola, M.; Lima, M.; Aluja, M. P.; Santos, C.

10.1101/304535 — molecular biology — Posted on 2018-04-19

775 Circularization of genes and chromosome by CRISPR in human cells

Moller, H. D.; Lin, L.; Xiang, X.; Petersen, T. S.; Huang, J.; Yang, L.; Kjeldsen, E.; Jensen, U. B.; Zhang, X.; Liu, X.; Xu, X.; Wang, J.; Yang, H.; Church, G. M.; Bolund, L.; Regenberg, B.; Luo, Y.

10.1101/304493 — genomics — Posted on 2018-04-19

776 ACDtool: a web-server extending the original Audic-Claverie statistical test to the comparison of large data sets of counts.

Claverie, J.-M.; Ta, T. N.

10.1101/304568 — bioinformatics — Posted on 2018-04-19

777 Using a robotic fish to investigate individual differences in social responsiveness in the guppy

Bierbach, D.; Landgraf, T.; Romanczuk, P.; Lukas, J.; Nguyen, H.; Wolf, M.; Krause, J.

10.1101/304501 — animal behavior and cognition — Posted on 2018-04-19

778 Endosymbiotic adaptations in three new bacterial species associated with Dictyostelium discoideum: Burkholderia agricolaris sp. nov., Burkholderia hayleyella sp. nov., and Burkholderia bonniea sp. nov.

Brock, D. A.; Hubert, A. M.; Noh, S.; DiSalvo, S.; Geist, K. S.; Haselkorn, T. S.; Queller, D.; Strassmann, J. E.

10.1101/304352 — microbiology — Posted on 2018-04-19

779 Widespread cis-regulation of RNA-editing in a large mammal

Lopdell, T. J.; Couldrey, C.; Tiplady, K.; Davis, S. R.; Snell, R. G.; Harris, B. L.; Littlejohn, M. D.

10.1101/304220 — genomics — Posted on 2018-04-19

780 Inhibition of EV71 replication by L3HYPDH, a newly identified interferon-stimulated gene product

Liu, J.; Liu, L.; Shinun Zeng, S.; Meng, X.; Lei, N.; Yang, H.; Li, R.; Guo, X.

10.1101/304345 — microbiology — Posted on 2018-04-19

781 Human cytomegalovirus tropism modulator UL148 interacts with SEL1L, a cellular factor that governs ER-associated degradation of the viral envelope glycoprotein, gO

Nguyen, C. C.; Siddiquey, M. N. A.; Zhang, H.; Kamil, J. P.

10.1101/304394 — microbiology — Posted on 2018-04-19

782 Skeletal Muscle Metrics on Clinical 18F- FDG PET/CT Predict Health Outcomes in Patients with Sarcoma

Foster, B. H.; Boutin, R. D.; Lenchik, L.; Gedeon, D.; Liu, Y.; Nittur, V.; Badawi, R. D.; Li, C.-S.; Canter, R. J.; Chaudhari, A. J.

10.1101/304279 — bioengineering — Posted on 2018-04-19

783 Non-intravenous, carbapenem-sparing antibiotics for the treatment of bacteremia due to ESBL or AMP-C β-lactamase: A propensity score study

Meije, Y.; Pigrau, C.; Fernandez-Hidalgo, N.; Clemente, M.; Ortega, L.; Sanz, X.; Loureiro-Amigo, J.; Sierra, M.; Morales-Cartagena, A.; Ribera, A.; Ayestaran, A.; Rodriguez-Bano, J.; Martinez-Montauti, J.

10.1101/304246 — pathology — Posted on 2018-04-18

784 Locoregional Radiogenomic Models Capture Gene Expression Heterogeneity in Glioblastoma

Depeursinge, A.; Szilagyi, T.; Liu, Y.; Kovacs, K.; Thomas, R.; Yeom, K.; Fischbein, N.; Rubin, D.; Iv, M.; Gevaert, O.

10.1101/304105 — bioinformatics — Posted on 2018-04-18

785 Stimulus vignetting and orientation selectivity in human visual cortex

Roth, Z. N.; Heeger, D.; Merriam, E.

10.1101/303719 — neuroscience — Posted on 2018-04-18

786 Highly dynamic chromatin interactions drive neurogenesis through gene regulatory networks

Malysheva, V.; Mendoza-Parra, M. A.; Blum, M.; Gronemeyer, H.

10.1101/303842 — molecular biology — Posted on 2018-04-18

787 Differential requirements of tubulin genes in mammalian forebrain development.

Bittermann, E.; Liegel, R. P.; Menke, C.; Timms, A.; Beier, D. R.; Kline-Fath, B.; Saal, H. M.; Stottmann, R.

10.1101/304196 — developmental biology — Posted on 2018-04-18

788 Spatio-temporally specific transcranial magnetic stimulation to test the locus of perceptual decision making in the human brain

Luber, B.; Jangraw, D. C.; Appelbaum, L. G.; Harrison, A.; Hilbig, S.; Beynel, L.; Jones, T.; Sajda, P.; Lisanby, S. H.

10.1101/304063 — neuroscience — Posted on 2018-04-18

789 A member of the ferlin calcium sensor family is essential for Toxoplasma gondii rhoptry secretion

Coleman, B. I.; Saha, S.; Sato, S.; Engelberg, K.; Ferguson, D. J. P.; Coppens, I.; Lodoen, M. B.; Gubbels, M.-J.

10.1101/304048 — microbiology — Posted on 2018-04-18

790 Using genetic drug-target networks to develop new drug hypotheses for major depressive disorder

Gaspar, H. A.; Gerring, Z.; Hübel, C.; Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, ; Middeldorp, C. M.; Derks, E. M.; Breen, G.

10.1101/304113 — genomics — Posted on 2018-04-18

791 Thrombocytopenia Microcephaly Syndrome - a novel phenotype associated with ACTB mutations

Latham, S. L.; Ehmke, N.; Reinke, P. Y. A.; Taft, M. H.; Lyons, M. J.; Friez, M. J.; Lee, J. A.; Hecker, R.; Fruehwald, M. C.; Becker, K.; Neuhann, T. M.; Horn, D.; Schrock, E.; Sarnow, K.; Gruetzmann, K.; Gawehn, L.; Klink, B.; Rump, A.; Chaponnier, C.; Knoefler, R.; Manstein, D. J.; Di Donato, N.

10.1101/303909 — genetics — Posted on 2018-04-18

792 MYBPC3 Mutations cause Hypertrophic Cardiomyopathy by Dysregulating Myosin: Implications for Therapy

Toepfer, C. N.; Wakimoto, H.; Garfinkel, A. C.; McDonough, B.; Liao, D.; Jiang, J.; Tai, A.; Joshua, G.; Lunde, I.; Lun, M.; Lynch, T.; Sadayappan, S.; Redwood, C.; Watkins, H.; Seidman, J.; Seidman, C.

10.1101/304204 — genetics — Posted on 2018-04-18

793 Kif18A promotes Hec1 dephosphorylation to coordinate chromosome alignment with kinetochore microtubule attachment

Kim, H.; Stumpff, J. K.

10.1101/304147 — cell biology — Posted on 2018-04-18

794 Automated analysis of small RNA datasets with RAPID

Karunanithi, S.; Simon, M.; Schulz, M. H.

10.1101/303750 — bioinformatics — Posted on 2018-04-18

795 Identification of co-evolving temporal networks

Elhesha, R.; Sarkar, A.; Boucher, C.; Kahveci, T.

10.1101/303974 — bioinformatics — Posted on 2018-04-18

796 Structural analysis of the active site and DNA binding of human cytidine deaminase APOBEC3B

Hou, S.; Silvas, T. V.; Leidner, F.; Nalivaika, E. A.; Matsuo, H.; Kurt Yilmaz, N.; Schiffer, C. A.

10.1101/304170 — biochemistry — Posted on 2018-04-18

797 Sapropterin Treatment Prevents Congenital Heart Defects Induced by Pregestational Diabetes in Mice

Engineer, A.; Saiyin, T.; Lu, X.; Kucey, A. S.; Urquhart, B. L.; Drysdale, T. A.; Norozi, K.; Feng, Q.

10.1101/304006 — pharmacology and toxicology — Posted on 2018-04-18

798 Dynamic and causal contribution of parietal cortex to perceptual decisions during category learning

Zhong, L.; Zhang, Y.; Duan, C. A.; Pan, J.; Xu, N.

10.1101/304071 — neuroscience — Posted on 2018-04-18

799 Theta-gamma coupling: a nonlinear dynamical model

Sheremet, A.; Zhou, Y.; Kennedy, J. P.; Qin, Y.; Burke, S. N.; Maurer, A. P.

10.1101/304238 — neuroscience — Posted on 2018-04-18

800 An optimal kernel-based method for gene set association analysis

Cui, Y.; He, T.; Li, S.; Zhong, P.-S.

10.1101/304055 — genetics — Posted on 2018-04-18

801 Beaked and killer whales show how collective prey behaviour foils acoustic predators

Aguilar de Soto, N.; Visser, F.; Madsen, P. T.; Tyack, P.; Ruxton, G.; Alcazar, J.; Arranz, P.; Johnson, M.

10.1101/303743 — ecology — Posted on 2018-04-18

802 Structural mechanism for Bruton’s tyrosine kinase activation at the cell membrane

Wang, Q.; Pechersky, Y.; Sagawa, S.; Pan, A. C.; Shaw, D. E.

10.1101/304097 — biophysics — Posted on 2018-04-18

803 Container-based bioinformatics with Pachyderm

Novella, J. A.; Emami Khoonsari, P.; Herman, S.; Whitenack, D.; Capuccini, M.; Burman, J.; Kultima, K.; Spjuth, O.

10.1101/299032 — bioinformatics — Posted on 2018-04-18

804 DCARS: Differential correlation across ranked samples

Ghazanfar, S.; Strbenac, D.; Ormerod, J. T.; Yang, J. Y. H.; Patrick, E.

10.1101/303735 — bioinformatics — Posted on 2018-04-18

805 S-Nitrosylation of STIM1 by neuronal nitric oxide synthase inhibits store-operated Ca2+ entry

Gui, L.; Zhu, J.; Lu, X.; Sims, S. M.; Lu, W.-Y.; Stathopulos, P. B.; Feng, Q.

10.1101/304022 — physiology — Posted on 2018-04-18

806 Cortical Reliability Amid Noise and Chaos

Nolte, M.; Reimann, M. W.; King, J. G.; Markram, H.; Muller, E. B.

10.1101/304121 — neuroscience — Posted on 2018-04-18

807 Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

Pulit, S. L.; Stoneman, C.; Morris, A. P.; Wood, A. R.; Glastonbury, C. A.; Tyrrell, J.; Yengo, L.; Ferreira, T.; Marouli, E.; Ji, Y.; Yang, J.; Jones, S.; Beaumont, R.; Croteau-Chonka, D. C.; Winkler, T. W.; GIANT Consortium, ; Hattersley, A. T.; Loos, R. J. F.; Hirschhorn, J. N.; Visscher, P. M.; Frayling, T. M.; Yaghootkar, H.; Lindgren, C. M.

10.1101/304030 — genetics — Posted on 2018-04-18

808 A Nasal Brush-based Classifier of Asthma Identified by Machine Learning Analysis of Nasal RNA Sequence Data

Pandey, G.; Pandey, O. P.; Rogers, A. J.; Ahsen, M. E.; Hoffman, G. E.; Raby, B. A.; Weiss, S. T.; Schadt, E. E.; Bunyavanich, S.

10.1101/145771 — systems biology — Posted on 2018-04-18

809 Correct CYFIP1 dosage is essential for synaptic inhibition and the excitatory/inhibitory balance.

Davenport, E. C.; Szulc, B.; Drew, J.; Taylor, J.; Morgan, T.; Higgs, N. F.; Lopez-Domenech, G.; Kittler, J. T.

10.1101/303446 — neuroscience — Posted on 2018-04-18

810 Resistome SNP Calling via Read Colored de Bruijn Graphs

Alipanahi, B.; Muggli, M. D.; Jundi, M.; Noyes, N.; Boucher, C.

10.1101/156174 — bioinformatics — Posted on 2018-04-18

811 Reproducible functional connectivity alterations are associated with autism spectrum disorder

Holiga, S.; Hipp, J. F.; Chatham, C. H.; Garces, P.; Spooren, W.; Logier D'Ardhuy, X.; Bertolino, A.; Bouquet, C.; Buitelaar, J. K.; Bours, C.; Rausch, A.; Oldehinkel, M.; Bouvard, M.; Amestoy, A.; Caralp, M.; Gueguen, S.; Ly-Le Moal, M.; Houenou, J.; Beckmann, C. F.; Loth, E.; Murphy, D.; Charman, T.; Tillmann, J.; Laidi, C.; Delorme, R.; Beggiato, A.; Gaman, A.; Scheid, I.; Leboyer, M.; d'Albis, M.-A.; Sevigny, J.; Czech, C.; Bolognani, F.; Honey, G. D.; Dukart, J.

10.1101/303115 — neuroscience — Posted on 2018-04-18

812 High quality whole genome sequence of an abundant Holarctic odontocete, the harbour porpoise (Phocoena phocoena)

Autenrieth, M.; Hartmann, S.; Lah, L.; Roos, A.; Dennis, A.; Tiedemann, R.

10.1101/246173 — genomics — Posted on 2018-04-18

813 Epigenetic changes induced by Bacteroides fragilis toxin

Allen, J.; Hao, S.; Sears, C. L.; Timp, W.

10.1101/301374 — genomics — Posted on 2018-04-18

814 A novel framework for inferring parameters of transmission from viral sequence data

Lumby, C. K.; Nene, N. R.; Illingworth, C. J. R.

10.1101/302331 — evolutionary biology — Posted on 2018-04-18

815 Targeting glutamine metabolism and redox state for leukemia therapy

Gregory, M. A.; Nemkov, T.; Zaberezhnyy, V.; Park, H. J.; Gehrke, S.; Hansen, K. C.; D Alessandro, A.; DeGregori, J.

10.1101/303529 — cancer biology — Posted on 2018-04-18

816 Non-cell autonomous Otx2 homeoprotein regulates visual cortex plasticity through Gadd45b/g

Apulei, J.; Kim, N.; Testa, D.; Ribot, J.; Morizet, D.; Bernard, C.; Jourdren, L.; Blugeon, C.; Di Nardo, A. A.; Prochiantz, A.

10.1101/163071 — neuroscience — Posted on 2018-04-18

817 Emergence of an adaptive command for orienting behavior in premotor brainstem neurons of barn owls

Cazettes, F.; Fischer, B. J.; Beckert, M. V.; Pena, J. L.

10.1101/119180 — neuroscience — Posted on 2018-04-18

818 Classes and continua of hippocampal CA1 inhibitory neurons revealed by single-cell transcriptomics

Harris, K. D.; Hochgerner, H.; Skene, N. G.; Magno, L.; Katona, L.; Bengtsson Gonzales, C.; Somogyi, P.; Kessaris, N.; Linnarsson, S.; Hjerling-Leffler, J.

10.1101/143354 — neuroscience — Posted on 2018-04-18

819 Deciphering hybrid larch reaction norms using random regression

Marchal, A.; Schlichting, C.; Gobin, R.; Balandier, P.; Millier, F.; Munoz, F.; Paques, L.; Sanchez, L.

10.1101/301119 — genetics — Posted on 2018-04-18

820 Intra-tumor heterogeneity defines treatment-resistant HER2+ breast tumors

Rye, I. H.; Trinh, A.; Saetersdal, A.; Nebdal, D.; Lingjaerde, O. C.; Almendro, V.; Polyak, K.; Borresen-Dale, A.-L.; Helland, A.; Markowetz, F.; Russnes, H. G.

10.1101/297549 — cancer biology — Posted on 2018-04-18

821 TFEA.ChIP: A tool kit for transcription factor binding site enrichment analysis capitalizing on ChIP-seq datasets

Puente-Santamaria, L.; del Peso, L.

10.1101/303651 — bioinformatics — Posted on 2018-04-18

822 Cellular resolution imaging of vestibular processing across the larval zebrafish brain

Favre-Bulle, I. A.; Vanwalleghem, G.; Taylor, M. A.; Rubinsztein-Dunlop, H.; Scott, E. K.

10.1101/302752 — neuroscience — Posted on 2018-04-18

823 Formation of functional, non-amyloidogenic fibres by recombinant Bacillus subtilis TasA

Erskine, E.; Morris, R.; Schor, M.; Earl, C.; Gillespie, R. M. C.; Bromley, K.; Sukhodub, T.; Clark, L.; Fyfe, P.; Serpell, L.; Stanley-Wall, N.; MacPhee, C. E.

10.1101/188995 — microbiology — Posted on 2018-04-18

824 Probing compression versus stretch activated recruitment of cortical actin and apical junction proteins using mechanical stimulations of suspended doublets.

Gao, X.; Acharya, B. R.; Engl, W. O.; de Mets, R.; Thiery, J.-P.; Yap, A.; Viasnoff, V.

10.1101/303644 — biophysics — Posted on 2018-04-18

825 Radial glial lineage progression and differential intermediate progenitor amplification underlie striatal compartments and circuit organization

Kelly, S. M.; He, M.; Lee, J.; Kim, Y.; Gibb, L. G.; Wu, P.; Matho, K.; Osten, P.; Graybiel, A. M.; Huang, Z. J.

10.1101/244327 — neuroscience — Posted on 2018-04-18

826 Cross-species systems analysis of evolutionary toolkits of neurogenomic response to social challenge

Saul, M. C.; Blatti, C.; Yang, W.; Bukhari, S. A.; Shpigler, H. Y.; Troy, J. M.; Seward, C. H.; Sloofman, L. G.; Chandrasekaran, S.; Bell, A. M.; Stubbs, L. J.; Robinson, G. E.; Zhao, S. D.; Sinha, S.

10.1101/219444 — genomics — Posted on 2018-04-18

827 The Structural Basis of IKs Ion-Channel Activation: Mechanistic Insights from Molecular Simulations

Ramasubramanian, S.; Rudy, Y.

10.1101/275180 — biophysics — Posted on 2018-04-18

828 EEG-based personal identification: comparison of different functional connectivity metrics

Fraschini, M.; Marcialis, G. L.; Didaci, L.

10.1101/254557 — bioengineering — Posted on 2018-04-18

829 The organization of intracortical connections by layer and cell class in the mouse brain

Harris, J. A.; Mihalas, S.; Hirokawa, K. E.; Whitesell, J. D.; Knox, J.; Bernard, A.; Bohn, P.; Caldejon, S.; Casal, L.; Cho, A.; Feng, D.; Gaudreault, N.; Gerfen, C.; Graddis, N.; Groblewski, P. A.; Henry, A.; Ho, A.; Howard, R.; Kuan, L.; Lecoq, J.; Luviano, J.; McConoghy, S.; Mortrud, M.; Naeemi, M.; Ng, L.; Oh, S. W.; Ouellette, B.; Sorensen, S.; Wakeman, W.; Wang, Q.; Williford, A.; Phillips, J.; Jones, A.; Koch, C.; Zeng, H.

10.1101/292961 — neuroscience — Posted on 2018-04-18

830 Nisin penetrates Staphylococcus aureus biofilms but shows differences in killing effects against sessile and planktonic cells.

Santos, F. G.; Pitts, B.; Stewart, P. S.; Mantovani, H. C.

10.1101/303636 — microbiology — Posted on 2018-04-18

831 Comparative analysis of IgG Responses to recombinant Qβ phage displayed MSP3 and UB05 in Dual HIV-malaria infected adults living in areas differing in Malaria transmission intensities

Lissom, A.; Ouambo, H. F.; Megnekou, R.; Okeke, M. I.; Ngu, L. L.; Netongo, P. M.; Ngoh, A. A.; Sanders, C. A.; Bawage, S.; Tchouangueu, T. F.; Tchadji, C. J.; Okoli, A. S.; Njambe Priso, G. D.; Garcia, R.; Gutierrez, A.; Chukwuma, G. O.; Esimone, C. O.; Achidi, E. A.; Mbacham, W. F.; Kaptue, L.; Leke, R. F.; Park, C. G.; Bopda Waffo, A.; Nchinda, G.

10.1101/303628 — immunology — Posted on 2018-04-18

832 Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

Strebinger, D.; Friman, E. T.; Deluz, C.; Govindan, S.; Alber, A. B.; Suter, D. M.

10.1101/299073 — developmental biology — Posted on 2018-04-18

833 Mass spectra alignment using virtual lock-masses

Brochu, F.; Plante, P.-L.; Drouin, A.; Laviolette, F.; Marchand, M.; Corbeil, J.

10.1101/292425 — bioinformatics — Posted on 2018-04-18

834 Polygenic adaptation and convergent evolution across both growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers

Bergey, C. M.; Lopez, M.; Harrison, G. F.; Patin, E.; Cohen, J.; Quintana-Murci, L.; Barreiro, L. B.; Perry, G. H.

10.1101/300574 — genomics — Posted on 2018-04-18

835 Pathway-based dissection of the genomic heterogeneity of cancer hallmarks’ acquisition with SLAPenrich

Iorio, F.; Garcia-Alonso, L.; Brammeld, J. S.; Martincorena, I.; Wille, D. R.; McDermott, U.; Saez-Rodriguez, J.

10.1101/077701 — bioinformatics — Posted on 2018-04-18

836 Modulation of mitochondrial Hsp90 (TRAP1) ATPase activity by calcium and magnesium

Agard, D. A.; Elnatan, D.

10.1101/300038 — biochemistry — Posted on 2018-04-18

837 MaSS-Simulator: A highly configurable MS/MS simulator for generating test datasets for big data algorithms

Awan, M. G.; Saeed, F.

10.1101/302489 — systems biology — Posted on 2018-04-18

838 Azithromycin reduces systemic inflammation and provides survival benefit in murine model of polymicrobial sepsis

Patel, A.; Joseph, J.; Periasamy, H.; Mokale, S.

10.1101/303610 — pharmacology and toxicology — Posted on 2018-04-18

839 Efficient sorting of single-unit activity from midbrain cells using KiloSort is as accurate as manual sorting.

Allen, M.; Chowdhury, T.; Wegener, M.; Moghaddam, B.

10.1101/303479 — neuroscience — Posted on 2018-04-18

840 Identification and biochemical characterization of a novel PP2C-like Ser/Thr phosphatase in E. coli

Rajagopalan, K.; Dworkin, J.

10.1101/303594 — microbiology — Posted on 2018-04-18

841 Phylogenetically novel uncultured microbial cells dominate Earth microbiomes

Lloyd, K. G.; Ladau, J.; Steen, A. D.; Yin, J.; Crosby, L.

10.1101/303602 — microbiology — Posted on 2018-04-18

842 Sub-voxel light-sheet microscopy for high-resolution, high-throughput volumetric imaging of large biomedical specimens

Fei, P.; Nie, J.; Lee, J.; Ding, Y.; Li, S.; Zhang, H.; Hagiwara, M.; Yu, T.; Segura, T.; Ho, C.-M.; Zhu, D.; Hsiai, T. K.

10.1101/255695 — bioengineering — Posted on 2018-04-18

843 Genetic structure of a patchily distributed philopatric migrant: implications for management and conservation

Bounas, A.; Tsaparis, D.; Efrat, R.; Gradev, G.; Gustin, M.; Mikulic, K.; Rodriguez, A.; Sara, M.; Kotoulas, G.; Sotiropoulos, K.

10.1101/216069 — genetics — Posted on 2018-04-18

844 Cortical recruitment determines learning dynamics and strategy

Ceballo, S.; Bourg, J.; Kempf, A.; Piwkowska, Z.; Daret, A.; Deneux, T.; Rumpel, S.; Bathellier, B.

10.1101/274936 — neuroscience — Posted on 2018-04-18

845 STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of omics data

Chen, H.; Albergante, L.; Hsu, J. Y.; Lareau, C. A.; Lo Bosco, G.; Guan, J.; Zhou, S.; Gorban, A. N.; Bauer, D. E.; Aryee, M. J.; Langenau, D. M.; Zinovyev, A.; Buenrostro, J. D.; Yuan, G.-C.; Pinello, L.

10.1101/302554 — genomics — Posted on 2018-04-18

846 DeepNeuron: An Open Deep Learning Toolbox for Neuron Tracing

Zhou, Z.; Kuo, H.-C.; Peng, H.; Long, F.

10.1101/254318 — bioinformatics — Posted on 2018-04-18

847 Expanded view of the ecological genomics of ant responses to climate change

Lau, M.; Ellison, A. M.; Nguyen, A. D.; Penick, C.; DeMarco, B.; Gotelli, N. J.; Sanders, N.; Dunn, R.; Helms Cahan, S.

10.1101/302679 — genomics — Posted on 2018-04-18

848 Rare variants in the genetic background modulate the expressivity of neurodevelopmental disorders

Pizzo, L.; Jensen, M.; Polyak, A.; Rosenfeld, J. A.; Mannik, K.; Krishnan, A.; McCready, E.; Pichon, O.; Le Caignec, C.; Van Dijck, A.; Pope, K.; Voorhoeve, E.; Yoon, J.; Stankiewicz, P.; Cheung, S. W.; Pazuchanics, D.; Huber, E.; Kumar, V.; Kember, R.; Mari, F.; Curro, A.; Castiglia, L.; Galesi, O.; Avola, E.; Mattina, T.; Fichera, M.; Mandara, L.; Vincent, M.; Nizon, M.; Mercier, S.; Beneteau, C.; Blesson, S.; Martin-Coignard, D.; Mosca-Boidron, A.-L.; Caberg, J. H.; Bucan, M.; Zeesman, S.; Nowaczyk, M. J. M.; Lefebvre, M.; Faivre, L.; Callier, P.; Skinner, C.; Keren, B.; Perrine, C.; Pronte

10.1101/257758 — genomics — Posted on 2018-04-18

849 Developmentally regulated transcription and silencing cycle of nuclear RNAi-targeted LTR retrotransposons in Caenorhabditis elegans

Ni, J. Z.; Kalinava, N.; Mendoza, S. G.; Gu, S. G.

10.1101/303230 — developmental biology — Posted on 2018-04-18

850 FAVITES: simultaneous simulation of transmission networks, phylogenetic trees, and sequences

Moshiri, N.; Ragonnet-Cronin, M.; Wertheim, J. O.; Mirarab, S.

10.1101/297267 — bioinformatics — Posted on 2018-04-18

851 Dynamic causal modelling of fluctuating connectivity in resting-state EEG

Van de Steen, F.; Almgren, H. B. J.; Razi, A.; Friston, K. J.; Marinazzo, D.

10.1101/303933 — neuroscience — Posted on 2018-04-18

852 The rodent lateral orbitofrontal cortex represents expected Pavlovian outcome value but not identity

Panayi, M. C.; Killcross, S.

10.1101/303800 — neuroscience — Posted on 2018-04-18

853 A transdiagnostic study of children with problems of attention, learning and memory (CALM)

Holmes, J.; Bryant, A.; The CALM Team, ; Gathercole, S. E.

10.1101/303826 — neuroscience — Posted on 2018-04-18

854 Age-related impairment of semantic integration into long-term memory is related to theta-alpha and low beta oscillations

Packard, P. A.; Steiger, T.; Fuentemilla, L.; Bunzeck, N.

10.1101/303859 — neuroscience — Posted on 2018-04-18

855 Large time step discrete-time modeling of sharp wave activity in hippocampal area CA3.

Malerba, P.; Rulkov, N. F.; Bazhenov, M.

10.1101/303917 — neuroscience — Posted on 2018-04-18

856 TGF-β induced CXCL13 in CD8+ T cells is associated with tertiary lymphoid structures in cancer

Workel, H. H.; Lubbers, J. M.; Arnold, R.; Prins, T. M.; van der Vlies, P.; de Lange, K.; Bosse, T.; van Gool, I. C.; Eggink, F. A.; Wouters, M. C.; Komdeur, F. L.; Creutzberg, C. L.; Kol, A.; Plat, A.; Glaire, M.; Church, D. N.; Nijman, H. W.; de Bruyn, M.

10.1101/303834 — immunology — Posted on 2018-04-18

857 Effects of protein size, thermodynamic stability, and net charge on cotranslational folding on the ribosome

Farias-Rico, J. A.; Ruud Selin, F.; Myronidi, I.; Von Heijne, G.

10.1101/303784 — biochemistry — Posted on 2018-04-18

858 High-resolution experimental and computational electrophysiology reveals weak β-lactam binding events in the porin PorB

Bartsch, A.; Llabres, S.; Pein, F.; Kattner, C.; Schön, M.; Diehn, M.; Tanabe, M.; Munk, A.; Zachariae, U.; Steinem, C.

10.1101/303891 — biophysics — Posted on 2018-04-18

859 Polychrome: Creating and Assessing Qualitative Palettes With Many Colors

Coombes, K.; Brock, G.; Abrams, Z. B.; Abruzzo, L. V.

10.1101/303883 — bioinformatics — Posted on 2018-04-18

860 Endothelial cells secreted ET-1 augments DN via inducing EM accumulation of MCs in ETBR-/- mice

Zou, H.-h.; Wang, L.; Shen, Y.; Zheng, X.; Xu, G.

10.1101/303768 — biochemistry — Posted on 2018-04-18

861 Isolation, Detection and Characterization of Aerobic Bacteria from Honey Samples of Bangladesh

Saha, S.; Ahammad, I.; Barmon, S.

10.1101/298695 — microbiology — Posted on 2018-04-18

862 Induction of muscle stem cell quiescence by the secreted niche factor Oncostatin M

Sampath, S. C.; Sampath, S. C.; Ho, A. T.; Corbel, S. Y.; Millstone, J. D.; Lamb, J.; Walker, J.; Kinzel, B.; Schmedt, C.; Blau, H. M.

10.1101/303586 — cell biology — Posted on 2018-04-18

863 Counting with DNA in metabarcoding studies: how should we convert sequence reads to dietary data?

Deagle, B.; Thomas, A. C.; McInnes, J. C.; Clarke, L. J.; Vesterinen, E. J.; Clare, E. L.; Kartzinel, T. R.; Eveson, J. P.

10.1101/303461 — ecology — Posted on 2018-04-18

864 A Coupled Network of Growth Transform Neurons for Spike-Encoded Auditory Feature Extraction

Gangopadhyay, A.; Aono, K.; Mehta, D.; Chakrabartty, S.

10.1101/303453 — neuroscience — Posted on 2018-04-18

865 Deep learning of quality control for stereotaxic registration of human brain MRI

Fonov, V.; Dadar, M.; The PREVENT-AD Research Group, ; Collins, D. L.

10.1101/303487 — neuroscience — Posted on 2018-04-18

866 STREAM: Single-cell Trajectories Reconstruction, Exploration And Mapping of omics data

10.1101/302554 — genomics — Posted on 2018-04-18

867 AchE-OGT dual inhibitors: Potential Partners in Handling Alzheimer’s Disease

Sharma, M.; Jainarayanan, A. K.

10.1101/303040 — bioinformatics — Posted on 2018-04-18

868 Targeting Human Retinoblastoma Binding Protein 4 (RBBP4) and 7 (RBBP7)

Abbey, M.; Trush, V.; Gibson, E.; Vedadi, M.

10.1101/303537 — biochemistry — Posted on 2018-04-18

869 Network analysis reveals differential metabolic functionality in antibiotic-resistant Pseudomonas aeruginosa

Dunphy, L. J.; Yen, P.; Papin, J. A.

10.1101/303289 — systems biology — Posted on 2018-04-18

870 Design and analysis of a Proportional-Integral-Derivative controller with biological molecules

Chevalier, M.; Gomez-Schiavon, M.; Ng, A.; El-Samad, H.

10.1101/303545 — synthetic biology — Posted on 2018-04-18

871 Integrated deep visual and semantic attractor neural networks predict fMRI pattern-information along the ventral object processing pathway

DEVEREUX, B. J.; Clarke, A. D.; Tyler, L. K.

10.1101/302406 — neuroscience — Posted on 2018-04-18

872 Burst firing and spatial coding in subicular principal cells

Simonnet, J.; Brecht, M.

10.1101/303354 — neuroscience — Posted on 2018-04-18

873 Anticipated ITD statistics built-in human sound localization

Pavao, R.; Sussman, E.; Fischer, B.; Pena, J.

10.1101/303347 — neuroscience — Posted on 2018-04-18

874 3D Functional Ultrasound Imaging of Pigeons

Rau, R.; Kruizinga, P.; Mastik, F.; Belau, M.; de Jong, N.; Bosch, J. G.; Scheffer, W.; Maret, G.

10.1101/302323 — neuroscience — Posted on 2018-04-18

875 Hair regeneration by small molecules that activate autophagy

Chai, M.; Jiang, M.; Vergnes, L.; Fu, X.; de Barros, S. C.; Jiao, J.; Herschman, H. R.; Crooks, G. M.; Reue, K.; Huang, J.

10.1101/303495 — developmental biology — Posted on 2018-04-18

876 Infectivity of dengue virus serotypes 1 and 2 is correlated to E protein intrinsic dynamics but not to envelope conformations

SHARMA, K. K.; LIM, X.-X.; TANTIRIMUDALIGE, S. N.; Gupta, A.; MARZINEK, J. K.; HOLDBROOK, D.; LIM, X. Y. E.; BOND, P. J.; ANAND, G. S.; WOHLAND, T.

10.1101/303560 — biophysics — Posted on 2018-04-18

877 Interact: Automated analysis of protein-ligand interactions by 1D and 2D NMR

Millard, P.; Lippens, G.

10.1101/215194 — bioinformatics — Posted on 2018-04-18

878 MaSS-Simulator: A highly configurable MS/MS simulator for generating test datasets for big data algorithms.

Awan, M. G.; Saeed, F.

10.1101/302489 — systems biology — Posted on 2018-04-18

879 The functional reach of the hippocampal memory system to the oculomotor system.

Ryan, J. D.; Shen, K.; Kacollja, A.; Tian, H.; Griffiths, J.; McIntosh, R.

10.1101/303511 — neuroscience — Posted on 2018-04-18

880 Enhanced Neurite Outgrowth and Regeneration in ALS Resistant Motor Neurons from SOD1 Mutant Mouse Models

Osking, Z. B.; Ayers, J. I.; Hildebrandt, R.; Skruber, K.; Eukovich, A. R.; Brown, H.; Ryu, D.; Golde, T. E.; Borchelt, D. R.; Read, T.-A.; Vitriol, E.

10.1101/303271 — neuroscience — Posted on 2018-04-18

881 A multicellular rosette-mediated collective dendrite extension

Fan, L.; Kovacevic, I.; Heiman, M.; Bao, Z.

10.1101/303503 — developmental biology — Posted on 2018-04-18

882 Transcribed enhancers in the macrophage immune response to Mycobacterium tuberculosis infection

Denisenko, E.; Guler, R.; Mhlanga, M. M.; Suzuki, H.; Brombacher, F.; Schmeier, S.

10.1101/303552 — bioinformatics — Posted on 2018-04-18

883 Gene Set Enrichment Analysis (GSEA) of Upregulated Genes in Cocaine Addiction Reveals miRNAs as Potential Therapeutic Agents

Ahammad, I.; Saha, S.

10.1101/303362 — bioinformatics — Posted on 2018-04-18

884 Developmentally regulated transcription and silencing cycle of nuclear RNAi-targeted LTR retrotransposons in Caenorhabditis elegans

Gu, S. G.; Ni, J. Z.; Kalinava, N.; Mendoza, S. G.

10.1101/303230 — developmental biology — Posted on 2018-04-17

885 B cells transiently exposed to antigen that return to quiescence respond to protein immunization similarly to naive B cells

Turner, J. S.; Ke, F.; Grigorova, I. L.

10.1101/303420 — immunology — Posted on 2018-04-17

886 Analysis of copy number variation from germline DNA can predict individual cancer risk

Toh, C.; Brody, J. P.

10.1101/303339 — genomics — Posted on 2018-04-17

887 Checkpoint signaling abrogation after cell cycle reentry reveals that differentiated neurons are mitotic cells

Walton, C. C.; Zhang, W.; Patino-Parrado, I.; Barrio-Alonso, E.; Garrido, J.-J.; Frade, J. M.

10.1101/288589 — cell biology — Posted on 2018-04-17

888 αB-crystallin inhibits amyloidogenesis by disassembling aggregation nuclei

Tkachenko, O.; Benesch, J. L. P.; Baldwin, A. J.

10.1101/300541 — biophysics — Posted on 2018-04-17

889 Population coding of pattern separation in the monkey hippocampus

Sakon, J. J.; Suzuki, W. A.

10.1101/302505 — neuroscience — Posted on 2018-04-17

890 Changes in patterns of neural activity underlie a time-dependent transformation of memory in rats and humans

Sekeres, M. J.; Winocur, G.; Moscovitch, M.; Anderson, J. A. E.; Pishdadian, S.; Wojtowicz, J. M.; St-Laurent, M.; McAndrews, M.-P.; Grady, C. L.

10.1101/303248 — neuroscience — Posted on 2018-04-17

891 Systematic evaluation of isoform function in literature reports of alternative splicing

Bhuiyan, S.; Ly, S.; Phan, M.; Huntington, B.; Hogan, E.; Liu, C. C.; Liu, J.; Pavlidis, P.

10.1101/303412 — molecular biology — Posted on 2018-04-17

892 Single cell analysis of quiescent HIV infection reveals host transcriptional profiles that regulate proviral latency

Bradley, T.; Ferrari, G.; Haynes, B. F.; Margolis, D. M.; Browne, E. P.

10.1101/303198 — microbiology — Posted on 2018-04-17

893 Sequencing and de novo assembly reveals genomic variations associated with differential responses of Candida albicans ATCC 10231 towards fluconazole, pH and non-invasive growth

Zore, G.; Thakre, A.; Patil, R.; Pradip, C.; Balan, B.

10.1101/302943 — genomics — Posted on 2018-04-17

894 Histone deposition plays an active role in recombination-dependent replication to balance genome2 stability upon replication stress

Hardy, J.; Day, D.; Ait Saada, A.; Teixeira-Silva, A.; Dupoiron, L.; Mojallali, F.; Freon, k.; Ochsenbein, F.; Hartmann, B.; lambert, s.

10.1101/303305 — genetics — Posted on 2018-04-17

895 Direct inference of base-pairing probabilities with neural networks improves RNA secondary structure prediction with pseudoknots

Akiyama, M.; Sakakibara, Y.; Sato, K.

10.1101/303172 — bioinformatics — Posted on 2018-04-17

896 IRES-mediated ribosome repositioning directs translation of a +1 overlapping ORF that enhances viral pathogenicity

Kerr, C. H.; Wang, Q. S.; Moon, K.-M.; Keatings, K.; Allan, D. W.; Foster, L. J.; Jan, E.

10.1101/303388 — biochemistry — Posted on 2018-04-17

897 Discovery of a two protease DNA damage checkpoint recovery mechanism

Burby, P. E.; Simmons, Z. W.; Schroeder, J. W.; Simmons, L. A.

10.1101/303297 — molecular biology — Posted on 2018-04-17

898 In situ structures of periplasmic flagella reveal a distinct cytoplasmic ATPase complex in Borrelia burgdorferi

Liu, J.; Qin, Z.; Manne, A.; Yu, Z.; Yerke, A.; Lees, K.; Motaleb, M. A.; Tu, J.; Norris, S. J.; Lin, T.; Li, C.

10.1101/303222 — microbiology — Posted on 2018-04-17

899 Holstein Friesian mid-lactation Milk Polar Metabolite Composition in relation to Dietary Fat Composition and Diacylglycerol O-acyltransferase 1 Genotype

te Pas, M.; Vervoort, J.; Kruijt, L.; Calus, M. P. L.; Smits, M. A.

10.1101/303099 — genomics — Posted on 2018-04-17

900 Magnesium suppresses defects in the formation of 70S ribosomes as well as in sporulation caused by lack of several individual ribosomal proteins.

Akanuma, G.; Yamazaki, K.; Yagishi, Y.; Iizuka, Y.; Ishizuka, M.; Kawamura, F.; Kato-Yamada, Y.

10.1101/300103 — genetics — Posted on 2018-04-17

901 Cdc23/Mcm10 Primase Generates the Lagging Strand-Specific Ribonucleotide Imprint in Fission Yeast

Singh, J.; Singh, B.; Bisht, K. K.; Upadhyay, U.; Kushwaha, A. C.; Nanda, J. S.; Srivastava, S.; Klar, A. J.

10.1101/303180 — genetics — Posted on 2018-04-17

902 Genetic divergence and phenotypic plasticity contribute to variation in cuticular hydrocarbons in the seaweed fly C. frigida

Berdan, E. L.; Enge, S.; Nylund, G.; Wellenreuther, M.; Martens, G. A.; Pavia, H.

10.1101/303206 — evolutionary biology — Posted on 2018-04-17

903 Heavy-tailed prior distributions for sequence count data: removing the noise and preserving large differences

Zhu, A.; Ibrahim, J. G.; Love, M. I.

10.1101/303255 — bioinformatics — Posted on 2018-04-17

904 The largest SWI/SNF polyglutamine domain is a pH sensor

Gutierrez, J. I.; Brittingham, G.; Wang, X.; Fenyo, D.; Holt, L. J.

10.1101/165043 — genetics — Posted on 2018-04-17

905 Correlation among antibiotic resistance and virulence traits in human gut microbiomes

Escudeiro, P.; Pothier, J.; Dionisio, F.; Nogueira, T.

10.1101/298190 — genomics — Posted on 2018-04-17

906 Identification of a secretion-enhancing cis regulatory targeting element (SECReTE) involved in mRNA localization and protein synthesis

Cohen-Zontag, O.; Lim, L. Q. J.; Dahary, D.; Olender, T.; Pilpel, Y.; Gerst, J.

10.1101/303156 — cell biology — Posted on 2018-04-17

907 Multimodal evidence on shape and surface information in individual face processing

Nemrodov, D.; Behrmann, M.; Niemeier, M.; Drobotenko, N.; Nestor, A.

10.1101/299933 — neuroscience — Posted on 2018-04-17

908 Atomic-level characterization of protein-protein association

Pan, A. C.; Jacobson, D.; Yatsenko, K.; Sritharan, D.; Weinreich, T. M.; Shaw, D. E.

10.1101/303370 — biophysics — Posted on 2018-04-17

909 Single-Cell RNA-seq Reveals a Subpopulation of Cells Underlying β Cell Expansion in the Postnatal Islets

Zhang, J. A.; Gu, C.; Smith, D. K.; Kong-Beltran, M.; Kljavin, N.; Hai, N.; Suriben, R.; Jeremy, S.; Modrusan, Z.; Peterson, A. S.

10.1101/303263 — developmental biology — Posted on 2018-04-17

910 Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach

Ahammad, I.

10.1101/302471 — systems biology — Posted on 2018-04-17

911 Limited Introgression Supports Division of Giraffe into Four Species

Winter, S.; Fennessy, J.; Janke, A.

10.1101/303057 — ecology — Posted on 2018-04-17

912 Generally applicable transcriptome-wide analysis of translational efficiency using anota2seq

Oertlin, C.; Lorent, J.; Gandin, V.; Murie, C.; Masvidal, L.; Cargnello, M.; Furic, L.; Topisirovic, I.; Larsson, O.

10.1101/106922 — bioinformatics — Posted on 2018-04-17

913 Genetics of brain age suggest an overlap with common brain disorders

Kaufmann, T.; van der Meer, D.; Doan, N. T.; Schwarz, E.; Lund, M. J.; Agartz, I.; Alnaes, D.; Barch, D. M.; Baur-Streubel, R.; Bertolino, A.; Bettella, F.; Beyer, M. K.; Boen, E.; Borgwardt, S.; Brandt, C. L.; Buitelaar, J.; Celius, E. G.; Cervenka, S.; Conzelmann, A.; Cordova-Palomera, A.; Dale, A. M.; de Quervain, D. J.- F.; Di Carlo, P.; Djurovic, S.; Dorum, E. S.; Eisenacher, S.; Elvsashagen, T.; Espeseth, T.; Fatouros-Bergman, H.; Flyckt, L.; Franke, B.; Frei, O.; Haatveit, B.; Haberg, A. K.; Harbo, H. F.; Hartman, C. A.; Heslenfeld, D.; Hoekstra, P. J.; Hogestol, E. A.; Jernigan, T.; Jo

10.1101/303164 — neuroscience — Posted on 2018-04-17

914 Expanded view of the ecological genomics of ant responses to climate change

Lau, M.; Ellison, A. M.; Nguyen, A. D.; Penick, C.; DeMarco, B.; Gotelli, N. J.; Sanders, N.; Dunn, R.; Helms Cahan, S.

10.1101/302679 — genomics — Posted on 2018-04-17

915 Spontaneous Pre-encoding Activation of Neural Patterns Predicts Memory

Sadeh, T.; Chen, J.; Goshen-Gottstein, Y.; Moscovitch, M.

10.1101/229401 — neuroscience — Posted on 2018-04-17

916 A scalable method to improve gray matter segmentation at ultra high field MRI

Gulban, O. F.; Schneider, M.; Marquardt, I.; Haast, R. A. M.; De Martino, F.

10.1101/245738 — neuroscience — Posted on 2018-04-17

917 Microbial community structure and microbial networks correspond to nutrient gradients within coastal wetlands of the Great Lakes

Horton, D. J.; Theis, K. R.; Uzarski, D. G.; Learman, D. R.

10.1101/217919 — microbiology — Posted on 2018-04-17

918 Membrane Diffusion Occurs by a Continuous-Time Random Walk Sustained by Vesicular Trafficking

Goiko, M.; de Bruyn, J. R.; Heit, B.

10.1101/208967 — biophysics — Posted on 2018-04-17

919 BLAST-based validation of metagenomic sequence assignments

Bazinet, A. L.; Ondov, B. D.; Sommer, D. D.; Ratnayake, S.

10.1101/181636 — bioinformatics — Posted on 2018-04-17

920 Computational Geometry for Modeling Neural Populations: from Visualization to Simulation

de Kamps, M.; Elle Lepperod, M.; Lai, Y. M.

10.1101/275412 — neuroscience — Posted on 2018-04-17

921 Mineral facilitated horizontal gene transfer: A new principle for evolution of life?

Sand, K. K.; Jelavic, S.

10.1101/235531 — evolutionary biology — Posted on 2018-04-17

922 Estimating the distance to an epidemic threshold

O'Dea, E. B.; Park, A. W.; Drake, J. M.

10.1101/247734 — epidemiology — Posted on 2018-04-17

923 Target variant detection in leukemia using unaligned RNA-Seq reads

Audemard, E.; Gendron, P.; Lavallee, V.-P.; Hebert, J.; Sauvageau, G.; Lemieux, S.

10.1101/295808 — bioinformatics — Posted on 2018-04-17

924 IMMAN: an R/Bioconductor package for Interolog protein network reconstruction, Mapping and Mining ANalysis

Ashtiani, M.; Nickchi, P.; Jahangiri-Tazehkand, S.; Safari, A.; Mirzaie, M.; Jafari, M.

10.1101/069104 — systems biology — Posted on 2018-04-17

925 egtplot: A Python Package for 3-Strategy Evolutionary Games

Mirzaev, I.; Williamson, D.; Scott, J. G.

10.1101/300004 — evolutionary biology — Posted on 2018-04-17

926 Germline genetics encode the resistance, risk, and lymphatic metastasis of triple-negative breast cancer in the southern Chinese population

Yang, M.; Fan, Y.; Zhang, Q.; Han, S.; Li, X.; Zhu, T.; Cheng, M.; Xu, J.; Yang, C.; Gao, H.; Zhang, C.; Zhang, M. Q.; Song, Y.-Q.; Niu, G.; Wang, K.

10.1101/302398 — cancer biology — Posted on 2018-04-17

927 Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach

Ahammad, I.

10.1101/302471 — systems biology — Posted on 2018-04-17

928 Cell type identity determines transcriptomic immune responses in Arabidopsis thaliana roots.

Rich, C.; Reitz, M.; Eichmann, R.; Jacobs, S.; Jenkins, D. J.; Esteban, E.; Ott, S.; Schafer, P.

10.1101/302448 — plant biology — Posted on 2018-04-17

929 Low-frequency direct cortical stimulation of left superior frontal gyrus enhances working memory performance

Alagapan, S.; Lustenberger, C.; Hadar, E.; Shin, H. W.; Frohlich, F.

10.1101/302588 — neuroscience — Posted on 2018-04-17

930 Defining a canonical ligand-binding pocket in the orphan nuclear receptor Nurr1

de Vera, I. M. S.; Munoz-Tello, P.; Dharmarajan, V.; Marciano, D. P.; Matta-Camacho, E.; Giri, P. K.; Shang, J.; Hughes, T. S.; Rance, M.; Griffin, P. R.; Kojetin, D. J.

10.1101/278440 — biophysics — Posted on 2018-04-17

931 Phase Separations Driven by RNA Scaffolds and Protein Sequestration in FXTAS

Botta-Orfila, T.; Cid-Samper, F.; Gelabert-Baldrich, I.; Lang, B.; Lorenzo-Gotor, N.; Delli Ponti, R.; WFM Severijnen, L.-A.; Bolognesi, B.; Gelpi, E.; Hukema-Felten, R. K.; Tartaglia, G. G.

10.1101/298943 — molecular biology — Posted on 2018-04-17

932 Distinguishing genetic correlation from causation across 52 diseases and complex traits

O'Connor, L. J.; Price, A. L.

10.1101/205435 — genetics — Posted on 2018-04-17

933 Large scale and significant expression from pseudogenes in Sodalis glossinidius - a facultative bacterial endosymbiont

Goodhead, I.; Blow, F.; Brownridge, P.; Hughes, M.; Kenny, J.; Krishna, R.; McLean, L.; Pongchaikul, P.; Beynon, R.; Darby, A. C.

10.1101/124388 — genomics — Posted on 2018-04-17

934 A cytoplasmic Argonaute protein promotes the inheritance of RNAi

Xu, F.; Feng, X.; Chen, X.; Weng, C.; Yan, Q.; Xu, T.; Hong, M.; Guang, S.

10.1101/235713 — genetics — Posted on 2018-04-17

935 EPA-ng: Massively Parallel Evolutionary Placement of Genetic Sequences

Barbera, P.; Kozlov, A. M.; Czech, L.; Morel, B.; Darriba, D.; Flouri, T.; Stamatakis, A.

10.1101/291658 — bioinformatics — Posted on 2018-04-17

936 The histone chaperone FACT coordinates H2A.X-dependent signaling and repair of DNA damage

Piquet, S.; Le Parc, F.; Bai, S.-K.; Chevallier, O.; Adam, S.; Polo, S. E.

10.1101/264952 — molecular biology — Posted on 2018-04-17

937 Identification of Significant Computational Building Blocks through Comprehensive Deep Dive of NGS Secondary Analysis Methods

Vasimuddin, M.; Misra, S.; Aluru, S.

10.1101/301903 — genomics — Posted on 2018-04-17

938 Machine learning reveals missing edges and putative interaction mechanisms in microbial ecosystem networks

DiMucci, D.; Kon, M.; Segre, D.

10.1101/286641 — bioinformatics — Posted on 2018-04-17

939 A k-mer-based method for the identification of phenotype-associated genomic biomarkers and predicting phenotypes of sequenced bacteria.

Aun, E.; Brauer, A.; Kisand, V.; Tenson, T.; Remm, M.

10.1101/302026 — bioinformatics — Posted on 2018-04-17

940 A discontinuous Galerkin model for fluorescence loss in photobleaching of intracellular polyglutamine protein aggregates

Hansen, C. V.; Schroll, H. J.; Wüstner, D.

10.1101/303107 — biophysics — Posted on 2018-04-17

941 BioLogic, a parallel approach to cell-based logic gates

Millacura, F. A.; Largey, B.; French, C. E.

10.1101/303032 — synthetic biology — Posted on 2018-04-17

942 Machine learning based classification of cells into chronological stages using single-cell transcriptomics.

Singh, S. P.; Janjuha, S.; Chaudhuri, S.; Reinhardt, S.; Dietz, S.; Eugster, A.; Bilgin, H.; Korkmaz, S.; Reid, J. E.; Zararsiz, G.; Ninov, N.

10.1101/303214 — bioinformatics — Posted on 2018-04-17

943 An optimized toolkit for precision base editing

Zafra, M. P.; Schatoff, E. M.; Katti, A.; Foronda, M.; Breinig, M.; Schweitzer, A. Y.; Simon, A.; Han, T.; Goswami, S.; Montgomery, E.; Thibado, J.; Sanchez-Rivera, F. J.; Shi, J.; Vakoc, C. R.; Lowe, S. W.; Tschaharganeh, D. F.; Dow, L. E.

10.1101/303131 — bioengineering — Posted on 2018-04-17

944 The lipid environment determines the activity of the E. coli ammonium transporter, AmtB

Dias Mirandela, G.; Tamburrino, G.; Hoskisson, P. A.; Zachariae, U.; Javelle, A.

10.1101/303065 — biochemistry — Posted on 2018-04-17

945 Reading Profiles in Multi-site Data with Missingness

Eckert, M.; Vaden, K.; Gebregziabher, M.; Dyslexia Data Consortium,

10.1101/269555 — neuroscience — Posted on 2018-04-17

946 TNER: A Novel Background Error Suppression Method for Mutation Detection in Circulating Tumor DNA

Deng, S.; Lira, M.; Huang, D.; Wang, K.; Valdez, C.; Kinong, J.; Rejto, P. A.; Bienkowska, J. R.; Hardwick, J.; Xie, T.

10.1101/214379 — bioinformatics — Posted on 2018-04-17

947 Systematic Discovery of Conservation States for Single-Nucleotide Annotation of the Human Genome

Sperlea, A. C.; Ernst, J.

10.1101/262097 — genomics — Posted on 2018-04-17

948 Prognostic models for Ebola virus disease derived from data collected at five treatment units in Sierra Leone and Liberia: performance, external validation, and risk visualization

Colubri, A.; Levine, A. C.; Siakor, M.; Wolfman, V.; Hartley, M.-A.; Sesay, T.; Felix, A.; Sabeti, P. C.

10.1101/294587 — bioinformatics — Posted on 2018-04-17

949 Population level rhythms in human skin: implications for circadian medicine

Wu, G.; Ruben, M. D.; Schmidt, R. E.; Francey, L. J.; Smith, D. F.; Anafi, R. C.; Hughey, J. J.; Tasseff, R.; Sherrill, J. D.; Oblong, J. E.; Mills, K. J.; Hogenesch, J. B.

10.1101/301820 — systems biology — Posted on 2018-04-17

950 Analysis of the genetic basis of height in large Jewish nuclear families

Zeevi, D.; Bloom, J. S.; Sadhu, M. J.; Ben Yehuda, A.; Zangen, D.; Levy-Lahad, E.; Kruglyak, L.

10.1101/303008 — genetics — Posted on 2018-04-17

951 Inferring Population Structure and Admixture Proportions in Low Depth Next-Generation Sequencing Data

Meisner, J.; Albrechtsen, A.

10.1101/302463 — genetics — Posted on 2018-04-17

952 Modeling site-specific amino-acid preferences deepens phylogenetic estimates of viral divergence

Hilton, S. K.; Bloom, J. D.

10.1101/302703 — evolutionary biology — Posted on 2018-04-17

953 A geometric approach to scaling individual distributions to macroecological patterns

Takashina, N.; Kusumoto, B.; Kubota, Y.; Economo, E. P.

10.1101/302810 — ecology — Posted on 2018-04-17

954 A Whole-Plant Monocot from the Early Cretaceous

Liu, Z.-J.; Chen, L.-J.; Wang, X.

10.1101/302075 — paleontology — Posted on 2018-04-17

955 Discordant expression profile between RNA and protein for the genes involved in immune response network in adenovirus type 2 infected cells

Zhao, H.; Chen, M.; Vald'es, A.; Lind, S.; Pettersson, U.

10.1101/302851 — microbiology — Posted on 2018-04-17

956 Structure-guided disruption of pseudopilus tip inhibits Type II secretion in Pseudomonas aeruginosa

Jia, Z.; Zhang, Y.; Faucher, F.; Zhang, W.; Wang, S.; Neville, N.; Poole, K.; Zheng, J.

10.1101/303123 — microbiology — Posted on 2018-04-17

957 Cultivation of 146 Clinical Strains of Nocardia species

Han, X. Y.; Holmes, A. J.; Golshan, M. A.

10.1101/302901 — microbiology — Posted on 2018-04-17

958 Dogs as reservoirs of Escherichia coli strains causing urinary tract infection in their owners

Damborg, P.; Gumpert, H.; Johansson, L.; Jana, B.; Frimodt-Moller, N.; Guardabassi, L.

10.1101/302885 — microbiology — Posted on 2018-04-17

959 A novel sialylation site on Neisseria gonorrhoeae lipooligosaccharide links heptose II lactose expression with pathogenicity

Ram, S.; Gulati, S.; Lewis, L. A.; Chakraborti, S.; Zheng, B.; DeOliveira, R. B.; Reed, G. W.; Cox, A. D.; Li, J.; St. Michael, F.; Stupak, J.; Su, X.-H.; Saha, S.; Landig, C. S.; Varki, A.; RICE, P. A.

10.1101/302968 — microbiology — Posted on 2018-04-17

960 Identification of a Novel Neutralizing and Two Non-Neutralizing Epitopes on Epstein-Barr Virus gp350 Protein

Mutsvunguma, L. Z.; Barasa, A.; Warden, C.; Foley, J.; Muniraju, M.; Mulama, D. H.; Ye, P.; Qin, H.; Wang, J.; Wu, X.; Mwangi, W.; Ogembo, J. G.

10.1101/302844 — immunology — Posted on 2018-04-17

961 bmotif: a package for counting motifs in bipartite networks

Simmons, B. I.; Sweering, M. J. M.; Dicks, L. V.; Sutherland, W. J.; Di Clemente, R.

10.1101/302356 — ecology — Posted on 2018-04-17

962 HMP16SData: Efficient Access to the Human Microbiome Project through Bioconductor

Schiffer, L.; Azhar, R.; Shepherd, L.; Ramos, M.; Geistlinger, L.; Huttenhower, C.; Dowd, J. B.; Segata, N.; Waldron, L.

10.1101/299115 — bioinformatics — Posted on 2018-04-17

963 Reproducing bench-scale cell growth and productivity

Hecht, A.; Filliben, J.; Munro, S. A.; Salit, M.

10.1101/302786 — synthetic biology — Posted on 2018-04-17

964 Representation of auditory motion directions and sound source locations in the human planum temporale

Battal, C.; Rezk, M. T.; Mattioni, S.; Collignon, O.

10.1101/302497 — neuroscience — Posted on 2018-04-17

965 Beyond Core Object Recognition: Recurrent processes account for object recognition under occlusion

Rajaei, K.; Mohsenzadeh, Y.; Ebrahimpour, R.; Khaligh-Razavi, S.-M.

10.1101/302034 — neuroscience — Posted on 2018-04-17

966 Hemispheric Asymmetry of Globus Pallidus Explains Reward-related Posterior Alpha Modulation in Humans

Mazzetti, C.; Staudigl, T.; Marshall, T. R.; Fallon, S. J.; Zumer, J. M.; Jensen, O.

10.1101/303016 — neuroscience — Posted on 2018-04-17

967 Low-frequency direct cortical stimulation of left superior frontal gyrus enhances working memory performance

Alagapan, S.; Lustenberger, C.; Hadar, E.; Shin, H. W.; Frohlich, F.

10.1101/302588 — neuroscience — Posted on 2018-04-17

968 Rules Governing Perception of Multiple Phosphenes by Human Observers

Bosking, W. H.; Foster, B.; Sun, P.; Beauchamp, M. S.; Yoshor, D.

10.1101/302547 — neuroscience — Posted on 2018-04-17

969 Fusion expression and anti-Aspergillus flavus activity of a novel inhibitory protein DN-AflR

Liang, Y.; kong, Q.; Yao, Y.; Xu, S.; Xie, X.

10.1101/302869 — microbiology — Posted on 2018-04-17

970 Development and validation of a phenotypic high-content imaging assay for assessing the antiviral activity of small-molecule inhibitors targeting the Zika virus

Bernatchez, J. A.; Yang, Z.; Coste, M.; Li, J.; Beck, S.; Liu, Y.; Clark, A. E.; Zhu, Z.; Luna, L. A.; Sohl, C.; Purse, B. W.; Li, R.; Siqueira-Neto, J. L.

10.1101/302927 — microbiology — Posted on 2018-04-17

971 Development and validation of a triplex qPCR assay to detect efflux pump-mediated antibiotic resistance in Burkholderia pseudomallei

Webb, J. R.; Price, E. P.; Somprasong, N.; Schweizer, H. P.; Baird, R. W.; Currie, B. J.; Sarovich, D. S.

10.1101/301960 — microbiology — Posted on 2018-04-17

972 integRATE: a desirability-based data integration framework for the prioritization of candidate genes across heterogeneous omics and its application to preterm birth

Eidem, H. R.; Steenwyk, J. L.; Wisecaver, J. H.; Capra, J. A.; Abbot, P.; Rokas, A.

10.1101/302612 — genomics — Posted on 2018-04-17

973 A new targeted capture method using bacterial artificial chromosome (BAC) libraries as baits for sequencing relatively large genes

Koganebuchi, K.; Gakuhari, T.; Takeshima, H.; Sato, K.; Fujii, K.; Kumabe, T.; Kasagi, S.; Sato, T.; Tajima, A.; Shibata, H.; Ogawa, M.; Oota, H.

10.1101/302760 — genomics — Posted on 2018-04-17

974 Hidden state models improve the adequacy of state-dependent diversification approaches using empirical trees, including biogeographical models

Caetano, D.; O'Meara, B.; Beaulieu, J.

10.1101/302729 — evolutionary biology — Posted on 2018-04-17

975 Novel organelle anion channels formed by chromogranin B drive normal granule maturation in endocrine cells

Yadav, G.; Zheng, H.; Yang, Q.; Douma, L.; Annamalai, M.; Bloom, L.; Mathews, C.; Jiang, Q.-X.

10.1101/302828 — cell biology — Posted on 2018-04-17

976 Avidity-driven polarity establishment via multivalent lipid-GTPase module interactions

Meca, J.; Massoni-Laporte, A.; Sartorel, E.; Martinez, D.; Loquet, A.; Habestein, B.; McCusker, D.

10.1101/303024 — cell biology — Posted on 2018-04-17

977 Six species of non-tuberculosis mycobacteria carry non-identical 16S rRNA gene copies

Takeda, K.; Chikamatsu, K.; Igarashi, Y.; Morishige, Y.; Murase, Y.; Aono, A.; Yamada, H.; Takaki, A.; Mitarai, S.

10.1101/302836 — bioinformatics — Posted on 2018-04-17

978 PRESTO, a new tool for integrating large-scale -omics data and discovering disease-specific signatures

McArdle, S.; Buscher, K.; Ehinger, E.; Pramod, A. B.; Riley, N.; Ley, K.

10.1101/302604 — bioinformatics — Posted on 2018-04-17

979 Discovering epistatic feature interactions from neural network models of regulatory DNA sequences

Greenside, P. G.; Shimko, T.; Fordyce, P.; Kundaje, A.

10.1101/302711 — bioinformatics — Posted on 2018-04-17

980 Development of an on-chip detection of Zika virus and antibodies simultaneously using array of nanowells

Semenova, T.; Voigt, A.; Donelan, W.; Aranyos, A. M.; Yamamoto, J. K.; Rathore, M.; Nguyen, C.

10.1101/302893 — bioengineering — Posted on 2018-04-17

981 A computational framework identifying concordant gene expression-neuropathology associations reveals Complex I as a potential Alzheimer’s disease therapeutic target

Celik, S.; Russell, J. C.; Mukherjee, S.; Crane, P. K.; Keene, D.; Bobb, J.; Kaeberlein, M.; Lee, S.-I.

10.1101/302737 — systems biology — Posted on 2018-04-17

982 Antimicrobial Efficacy and Safety of a Novel Gas Plasma-Activated Catheter Lock Solution

Bhatt, S.; Mehta, P.; Chen, C.; Daines, D. A.; Mermel, L.; Chen, H.; Kong, M.

10.1101/302919 — microbiology — Posted on 2018-04-17

983 Microscale tracking of coral disease reveals timeline of infection and heterogeneity of polyp fate.

Gavish, A. R.; Shapiro, O. H.; Kramarsky-Winter, E.; Vardi, A.

10.1101/302778 — microbiology — Posted on 2018-04-17

984 Genomic consequences of a recent three-way admixture in supplemented wild brown trout populations revealed by ancestry tracts

Leitwein, M.; Gagnaire, P.-A.; Desmarais, E.; Berrebi, P.; GUINAND, B.

10.1101/302380 — genomics — Posted on 2018-04-17

985 Intellectual phenotypes in autism strongly correlate with gene dosage changes and exon locations of truncating mutations

Chiang, A. H.; Chang, J.; Vitkup, D.

10.1101/270850 — genetics — Posted on 2018-04-17

986 Genome-wide association study of social genetic effects on 170 phenotypes in laboratory mice

Baud, A.; Casale, F. P.; Nicod, J.; Stegle, O.

10.1101/302349 — genetics — Posted on 2018-04-17

987 A prior-based approach for hypothesis comparison and its utility to discern among temporal scenarios of divergence

Zarza, E.; O'Hara, R. B.; Kolb, A.; Pfenninger, M.

10.1101/302539 — evolutionary biology — Posted on 2018-04-17

988 FESTA: Flexible Exon-based Splicing and Transcription Annotation

Rago, A.; Colbourne, J. K.

10.1101/300947 — bioinformatics — Posted on 2018-04-17

989 Mode of Growth and Temperature Dependence on Expression of Atrazine-degrading Genes in Pseudomonas sp. strain ADP Biofilms

Delcau, M. A.; Henry, V.; Pattee, E.; Peeples, T. L.

10.1101/302877 — bioengineering — Posted on 2018-04-17

990 Direct Small Molecule Activation of Mitofusins

Zacharioudakis, E.; Biris, N.; Garner, T.; Chen, Y.; Pekson, R.; Dhingra, R.; Santulli, G.; Kirshenbaum, L.; Kitsis, R.; Gavathiotis, E.

10.1101/301713 — biochemistry — Posted on 2018-04-17

991 Dissociating time and number in reinforcement rate learning

Austen, J.; Pickering, C.; Sprengel, R.; Sanderson, D.

10.1101/302372 — animal behavior and cognition — Posted on 2018-04-17

992 Whole-brain calcium imaging during physiological vestibular stimulation in larval zebrafish

Migault, G.; Panier, T.; Candelier, R.; Debregeas, G.; Bormuth, V.

10.1101/300350 — neuroscience — Posted on 2018-04-17

993 Retracing the Hawaiian silversword radiation despite phylogenetic, biogeographic, and paleogeographic uncertainty

Landis, M. J.; Freyman, W. A.; Baldwin, B. G.

10.1101/301887 — evolutionary biology — Posted on 2018-04-17

994 The mechanical impact of col11a2 loss on joints; col11a2 mutant zebrafish show changes to joint development and function which lead to early onset osteoarthritis

Lawrence, E.; Kague, E.; Aggleton, J. A.; Harniman, R. L.; Roddy, K. A.; Hammond, C. L.

10.1101/302307 — developmental biology — Posted on 2018-04-17

995 Poly-Target Selection Identifies RNA Broad-Spectrum Inhibitors of HIV Reverse Transcriptases

Alam, K. K.; Chang, J. L.; Lange, M. J.; Nguyen, P. D. M.; Sawyer, A. W.; Burke, D. H.

10.1101/302745 — molecular biology — Posted on 2018-04-17

996 Genetic contributions to ectopic sperm cell migration in Caenorhabditis nematodes

Ting, J. J.; Tsai, C. N.; Cutter, A. D.

10.1101/302562 — genetics — Posted on 2018-04-17

997 Repulsive Guidance Molecule Acts in Axon Branching in Caenorhabditis elegans

Tsutsui, K.; Kim, H.-S.; Kubota, Y.; Shibata, Y.; Tian, C.; Liu, J.; Nishiwaki, K.

10.1101/301275 — developmental biology — Posted on 2018-04-16

998 HIR-1 Mediates Response to Hypoxia-Induced Extracellular Matrix Remodeling

Vozdek, R.; Long, Y.; Ma, D. K.

10.1101/302638 — cell biology — Posted on 2018-04-16

999 Evidence for a Solenoid Phase of Supercoiled DNA

Dittmore, A.; Neuman, K. C.

10.1101/302661 — biophysics — Posted on 2018-04-16

1000 Germline genetics encode the resistance, risk, and lymphatic metastasis of triple-negative breast cancer in the southern Chinese population

Yang, M.; Fan, Y.; Zhang, Q.; Han, S.; Li, X.; Zhu, T.; Cheng, M.; Xu, J.; Yang, C.; Gao, H.; Zhang, C.; Zhang, M. Q.; Song, Y.-Q.; Niu, G.; Wang, K.

10.1101/302398 — cancer biology — Posted on 2018-04-16

1001 The impact of fibronection stripe patterns on the cellular and nuclear morphology of fibroblasts

Mamaghani, P.; Donald, A.

10.1101/302687 — biophysics — Posted on 2018-04-16

1002 Prediction of response to anti-cancer drugs becomes robust via network integration of molecular data

Franco, M.; Jeggari, A.; Peuget, S.; Böttger, F.; Selivanova, G.; Alexeyenko, A.

10.1101/301838 — cancer biology — Posted on 2018-04-16

1003 Muscleblind regulates Drosophila Dscam2 cell-type-specific alternative splicing

Li, J. S. S.; Millard, S. S.

10.1101/297101 — neuroscience — Posted on 2018-04-16

1004 SLC6A4 binding site and acute prosocial effects of (+/-)-3,4-methylendioxymethamphetamine (MDMA) are evolutionarily conserved in Octopus bimaculoides.

Edsinger, E.; Dolen, G.

10.1101/301192 — evolutionary biology — Posted on 2018-04-16

1005 Reduced top-down connectivity as an underlying mechanism for psychotic experiences in healthy people

Dzafic, I.; Randeniya, R.; Garrido, M. I.

10.1101/296988 — neuroscience — Posted on 2018-04-16

1006 Probing the origin of matching functional jaws: roles of Dlx5/6 in cranial neural crest cells.

Shimizu, M.; Narboux-Neme, N.; Gitton, Y.; de Lombares, C.; Fontaine, A.; Alfama, G.; Kitazawa, T.; Kawamura, Y.; Heude, E.; Marshall, L.; Higashiyama, H.; Wada, Y.; Kurihara, Y.; Kurihara, H.; Levi, G.

10.1101/296665 — developmental biology — Posted on 2018-04-16

1007 Working memory availability affects neural indices of distractor processing during visual search

Henare, D. T.; Buckley, J.; Corballis, P. M.

10.1101/295378 — neuroscience — Posted on 2018-04-16

1008 Modelling phage-bacteria interactions driving predation and horizontal gene transfer

Sousa, J. M. d.; Alsaadi, A.; Haaber, J.; Ingmer, H.; Rocha, E. P. C.

10.1101/291328 — microbiology — Posted on 2018-04-16

1009 Biology and taxonomy of crAss-like bacteriophages, the most abundant virus in the human gut

Guerin, E.; Shkoporov, A.; Stockdale, S.; Clooney, A. G.; Ryan, F. J.; Sutton, T. D. S.; Draper, L. A.; Gonzalez-Tortuero, E.; Ross, R. P.; Hill, C.

10.1101/295642 — microbiology — Posted on 2018-04-16

1010 Pisces: An Accurate and Versatile Variant Caller for Somatic and Germline Next-Generation Sequencing Data

Dunn, T.; Berry, G.; Emig-Agius, D.; Jiang, Y.; Lei, S.; Iyer, A.; Udar, N.; Chuang, H.-Y.; Hegarty, J.; Dickover, M.; Klotzle, B.; Robbins, J.; Bibikova, M.; Peeters, M.; Stromberg, M.

10.1101/291641 — bioinformatics — Posted on 2018-04-16

1011 Toward Precision Molecular Surgery: Robust, Selective Induction of Microhomology-mediated End Joining in vivo

Ata, H.; Ekstrom, T. L.; Martinez-Galvez, G.; Mann, C. M.; Dvornikov, A. V.; Schaefbauer, K. J.; Ma, A. C.; Dobbs, D.; Clark, K. J.; Ekker, S. C.

10.1101/291187 — molecular biology — Posted on 2018-04-16

1012 CELLector: Genomics Guided Selection of Cancer in vitro Models

Najgebauer, H.; Yang, M.; Francies, H.; Stronach, E. A.; Garnett, M. J.; Saez-Rodriguez, J.; Iorio, F.

10.1101/275032 — bioinformatics — Posted on 2018-04-16

1013 Nanoscale colocalization of NK cell activating and inhibitory receptors controls signal integration

Tomaz, D.; Pereira, P. M.; Guerra, N.; Dyson, J.; Henriques, R.; Gould, K.

10.1101/266429 — immunology — Posted on 2018-04-16

1014 Rarity and conservation status do not predict vertebrate population trends

Daskalova, G. N.; Myers-Smith, I. H.; Godlee, J. L.

10.1101/272898 — ecology — Posted on 2018-04-16

1015 Measurement of myofilament calcium in living cardiomyocytes using a targeted genetically encoded indicator

Robinson, P.; Sparrow, A. J.; Broyles, C. N.; Sievert, K.; Chang, Y.-F.; Brook, F. A.; Zhang, X.; Watkins, H.; Abassi, Y. A.; Geeves, M. A.; Redwood, C.; Daniels, M. J.

10.1101/268003 — cell biology — Posted on 2018-04-16

1016 Cross-species systems analyses reveal a shared brain transcriptional response to social challenge

10.1101/219444 — genomics — Posted on 2018-04-16

1017 Is the sky the limit? On the expansion threshold of a species’ range

Polechova, J.

10.1101/234377 — evolutionary biology — Posted on 2018-04-16

1018 An Investigation of Detection Biases in the Unattended Periphery During Simulated Driving

Li, M. K.; Lau, H.; Odegaard, B.

10.1101/257741 — animal behavior and cognition — Posted on 2018-04-16

1019 Recurrent Auto-Encoding Drift Diffusion Model

Moens, V.; Zenon, A.

10.1101/220517 — neuroscience — Posted on 2018-04-16

1020 Rapid Identification of Stable Clusters in Bacterial Populations Using the Adjusted Wallace Coefficient

Barker, D. O.; Carrico, J. A.; Kruczkiewicz, P.; Palma, F.; Rossi, M.; Taboada, E. N.

10.1101/299347 — genomics — Posted on 2018-04-16

1021 Near-atomic cryo-EM structure of yeast kinesin 5-microtubule complex reveals a distinct binding footprint

von Loeffelholz, O.; Pena, A.; Drummond, D. R.; Cross, R.; Moores, C.

10.1101/302455 — biophysics — Posted on 2018-04-16

1022 RNA binding and HEPN nuclease activation are decoupled in CRISPR-Cas13a

Tambe, A.; East-Seletsky, A.; Knott, G. J.; Doudna, J. A.; O'Connell, M. R.

10.1101/190603 — biochemistry — Posted on 2018-04-16

1023 Identification of Key Proteins Involved in Axon Guidance Related Disorders: A Systems Biology Approach

Ahammad, I.

10.1101/302471 — systems biology — Posted on 2018-04-16

1024 A control theoretic model of adaptive behavior in dynamic environments

Ritz, H.; Nassar, M. R.; Frank, M. J.; Shenhav, A.

10.1101/204271 — neuroscience — Posted on 2018-04-16

1025 Dual spindle formation in zygotes keeps parental genomes apart in early mammalian embryos

Reichmann, J.; Nijmeijer, B.; Hossain, M. J.; Eguren, M.; Schneider, I.; Politi, A. Z.; Roberti, M. J.; Hufnagel, L.; Hiiragi, T.; Ellenberg, J.

10.1101/198275 — cell biology — Posted on 2018-04-16

1026 SNP Calling via Read Colored de Bruijn Graphs

Alipanahi, B.; Muggli, M. D.; Jundi, M.; Noyes, N.; Boucher, C.

10.1101/156174 — bioinformatics — Posted on 2018-04-16

1027 Underwater hyperspectral classification of deep sea corals exposed to 2-methylnaphthalene

Letnes, P. A.; Hansen, I. M.; Aas, L. M.; Eide, I.; Pettersen, R.; Tassara, L.; Receveur, J.; le Floch, S.; Guyomarch, J.; Camus, L.; Bytingsvik, J.

10.1101/150060 — biochemistry — Posted on 2018-04-16

1028 A two-enzyme adaptive unit in bacterial folate metabolism

Schober, A. F.; Ingle, C.; Park, J. O.; Chen, L.; Rabinowitz, J. D.; Junier, I.; Rivoire, O.; Reynolds, K. A.

10.1101/120006 — systems biology — Posted on 2018-04-16

1029 Waves of chromatin modifications in mouse dendritic cells in response to LPS stimulation

Vandenbon, A.; Kumagai, Y.; Suzuki, Y.; Nakai, K.

10.1101/066472 — genomics — Posted on 2018-04-16

1030 Cell type identity determines transcriptomic immune responses in Arabidopsis thaliana roots.

Rich, C.; Reitz, M.; Eichmann, R.; Jacobs, S.; Jenkins, D. J.; Eddi, E.; Ott, S.; Schafer, P.

10.1101/302448 — plant biology — Posted on 2018-04-16

1031 H3.3K4M destabilizes enhancer epigenomic writers MLL3/4 and impairs adipose tissue development

Jang, Y.; Wang, C.; Broun, A.; Park, Y.-K.; Zhuang, L.; Lee, J.-E.; Froimchuk, E.; Liu, C.; Ge, K.

10.1101/301986 — molecular biology — Posted on 2018-04-16

1032 Insufficient fumarase contributes to generating reactive oxygen species in Dahl salt sensitive rats

Hou, E.; Zheng, X.; Yang, Z.; Li, X.; Liu, Z.; Chen, M.; Li, X.; Liang, M.; Tian, Z.

10.1101/302182 — molecular biology — Posted on 2018-04-16

1033 Identification of 12 genetic loci associated with human healthspan

Zenin, A.; Tsepilov, Y.; Sharapov, S.; Getmantsev, E.; Menshikov, L.; Fedichev, P.; Aulchenko, Y.

10.1101/300889 — epidemiology — Posted on 2018-04-16

1034 The effect of education and general cognitive ability on smoking: A Mendelian randomisation study

Sanderson, E.; Davey Smith, G.; Munafo, M.

10.1101/299826 — epidemiology — Posted on 2018-04-16

1035 The relationship between transmission time and clustering methods in Mycobacterium tuberculosis epidemiology

Meehan, C. J.; Moris, P.; Kohl, T. A.; Pecerska, J.; Akter, S.; Merker, M.; Utpatel, C.; Beckert, P.; Gehre, F.; Lempens, P.; Stadler, T.; Kaswa, M. K.; Kuhnert, D.; Niemann, S.; de Jong, B. C.

10.1101/302232 — epidemiology — Posted on 2018-04-16

1036 Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium

Koivula, R. W.; Forgie, I. M.; Kurbasic, A.; Vinuela, A.; Heggie, A.; Giordano, G. N.; Hansen, T. H.; Hudson, M.; Koopman, A.; Rutters, F.; Siloaho, M.; Allin, K. H.; Brage, S.; Brorsson, C. A.; Dawed, A. Y.; De Masi, F.; Groves, C. J.; Kokkola, T.; Mahajan, A.; Perry, M. H.; Rauh, S. P.; Ridderstrale, M.; Teare, H. J.; Thomas, E. L.; Tura, A.; Vestergaard, H.; White, T.; Adamski, J.; Bell, J. D.; Brunak, S.; Dekker, J.; Dermitzakis, E. T.; Froguel, P.; Frost, G.; Gupta, R.; Torben, H.; Hattersley, A.; Jablonka, B.; Laakso, M.; McDonald, T. J.; Pedersen, O.; Schwenk, J. M.; Pavo, I.; Mari, A.;

10.1101/300244 — epidemiology — Posted on 2018-04-16

1037 The effect of body mass index on smoking behaviour and nicotine metabolism: a Mendelian randomization study

Taylor, A.; Richmond, R.; Palviainen, T.; Loukula, A.; Kaprio, J.; Relton, C.; Davey Smith, G.; Munafo, M.

10.1101/299834 — epidemiology — Posted on 2018-04-16

1038 Genomic and epidemiological monitoring of yellow fever virus transmission potential

Faria, N. R.; Kraemer, M. U. G.; Hill, S.; de Jesus, J. G.; Aguiar, R. S. d.; Iani, F. C. M.; Xavier, J.; Quick, J.; Plessis, L. d.; Dellicour, S.; Theze, J.; Carvalho, R. D. O.; Baele, G.; Wu, C.-H.; Silveira, P. P.; Arruda, M. B.; Pereira, M. A.; Pereira, G. d. C.; Lourenco, J.; Obolski, U.; Abade, L.; Vasylyeva, T.; Giovanetti, M.; Li, D.; Weiss, D. J.; Wint, W. G. R.; Shearer, F. M.; Funk, S.; Nikolay, B.; Adelino, T. E. R.; Oliveira, M. A. A.; Silva, M. V. F.; Sacchetto, L.; Figueiredo, P. d. O.; Rezende, I. M. d.; de Mello, E. M.; Said, R. F. d. C.; Santos, D. A. d.; Ferraz, M. L.; de Br

10.1101/299842 — epidemiology — Posted on 2018-04-16

1039 Placental-expanded, mesenchymal cells improve muscle function following hip arthroplasty

Winkler, T.; Perka, C.; von Roth, P.; Agres, A. N.; Plage, H.; Preininger, B.; Pumberger, M.; Geissler, S.; Lukasiewicz Hagai, E.; Ofir, R.; Pinzur, L.; Eyal, E.; Stoltenburg-Didinger, G.; Meisel, C.; Consentius, C.; Streitz, M.; Reinke, P.; Duda, G. N.; Volk, H.-D.

10.1101/297739 — clinical trials — Posted on 2018-04-16

1040 Integrative analysis of DNA methylation suggests down-regulation of oncogenic pathways and reduced de-novo mutation in survival outliers of glioblastoma

Hwang, T.; Mathios, D.; McDonald, K. L.; Daris, I.; Park, S.-H.; Burger, P. C.; Kim, S.; Dho, Y.-S.; Carolyn, H.; Bettegowda, C.; Shin, J. H.; Lim, M.; Park, C.-K.

10.1101/302042 — cancer biology — Posted on 2018-04-16

1041 Tuning site-specific dynamics to drive allosteric activation in a pneumococcal zinc uptake regulator

Capdevila, D.; Huerta, F.; Edmonds, K. A.; Le, M. T.; Wu, H.; Giedroc, D. P.

10.1101/301853 — biochemistry — Posted on 2018-04-16

1042 Inferior parietal lobule and early visual areas support elicitation of individualized meanings during narrative listening

Saalasti, S.; Alho, J.; Bar, M.; Glerean, E.; Honkela, T.; Kauppila, M.; Sams, M.; Jaaskelainen, I.

10.1101/301812 — neuroscience — Posted on 2018-04-16

1043 Improving early epidemiological assessment of emerging Aedes-transmitted epidemics using historical data

Riou, J.; Poletto, C.; Boëlle, P.-Y.

10.1101/300954 — epidemiology — Posted on 2018-04-16

1044 Community origins and regional differences in plasmid-mediated fluoroquinolone resistant Enterobacteriaceae infections in children

Logan, L. K.; Medernach, R. L.; Rispens, J. R.; Marshall, S. H.; Hujer, A. M.; Domitrovic, T. N.; Rudin, S. D.; Zheng, X.; Qureshi, N. K.; Konda, S.; Hayden, M.; Weinstein, R. A.; Bonomo, R. A.

10.1101/301457 — epidemiology — Posted on 2018-04-16

1045 A k-mer-based method for the identification of phenotype-associated genomic biomarkers and predicting phenotypes of sequenced bacteria.

Aun, E.; Brauer, A.; Kisand, V.; Tenson, T.; Remm, M.

10.1101/302026 — bioinformatics — Posted on 2018-04-16

1046 Selection of time points for costly experiments: a comparison between human intuition and computer-aided experimental design

Ezer, D.; Keir, J. C.

10.1101/301796 — bioinformatics — Posted on 2018-04-16

1047 Assessing key decisions for transcriptomic data integration in biochemical networks

Richelle, A.; Joshi, C.; Lewis, N. E.

10.1101/301945 — systems biology — Posted on 2018-04-16

1048 Cross-sectional white matter microstructure differences in aging and mindfulness

Boekel, W.; Hsieh, S.

10.1101/301739 — neuroscience — Posted on 2018-04-16

1049 Spontaneous resistance to phage NPV1 confers increased daptomycin susceptibility in Enterococcus faecalis OG1RF

Ho, K.; Huo, W.; Pas, S.; Palmer, K.

10.1101/301929 — microbiology — Posted on 2018-04-16

1050 Structural variants and selective sweep foci contribute to insecticide resistance in the Drosophila melanogaster genetic reference panel

Battlay, ; Green, L.; Leblanc, P.; Schmidt, J. M.; FOURNIER-LEVEL, A.; Robin, C.

10.1101/301937 — genetics — Posted on 2018-04-16

1051 DNA local structure decreases mutation rates

Duan, C.; Huan, Q.; Chen, X.; Wu, S.; Carey, L. B.; He, X.; Qian, W.

10.1101/302133 — genetics — Posted on 2018-04-16

1052 A protocol for an intercomparison of biodiversity and ecosystem services models using harmonized land-use and climate scenarios

Kim, H.; Rosa, I. M. D.; Alkemade, R.; Leadley, P.; Hurtt, G.; Popp, A.; van Vuuren, D.; Anthoni, P.; Arneth, A.; Baisero, D.; Caton, E.; Chaplin-Kramer, R.; Chini, L.; De Palma, A.; Di Fulvio, F.; Di Marco, M.; Espinoza, F.; Ferrier, S.; Fujimori, S.; Gonzalez, R. E.; Guerra, C.; Hartfoot, M.; Harwood, T. D.; Hasegawa, T.; Haverd, V.; Havlik, P.; Hellweg, S.; Hill, S. L. L.; Hirata, A.; Hoskins, A. J.; Janse, J. H.; Jetz, W.; Johnson, J. A.; Krause, A.; Leclere, D.; Martins, I. S.; Matsui, T.; Merow, C.; Obersteiner, M.; Ohashi, H.; Poulter, B.; Purvis, A.; Quesada, B.; Rondinini, C.; Schippe

10.1101/300632 — ecology — Posted on 2018-04-16

1053 Revolutionising the design and analysis of protein engineering experiments using fractional factorial design

Harborne, S. P.; Wotherspoon, D.; Michie, J.; McComb, A.; Kotila, T.; Gilmour, S.; Goldman, A.

10.1101/298273 — bioengineering — Posted on 2018-04-16

1054 Population level rhythms in human skin: implications for circadian medicine

Wu, G.; Ruben, M.; Schmidt, R.; Francey, L.; Smith, D.; Anafi, R.; Hughey, J.; Tasseff, R.; Sherrill, J.; Oblong, J.; Mills, K.; Hogenesch, J.

10.1101/301820 — systems biology — Posted on 2018-04-16

1055 Exogenous putrescine alleviates photoinhibition caused by salt stress through increasing cyclic electron flow in cucumber

Wu, X.; Shu, S.; Wang, Y.; Yuan, R.; Guo, S.

10.1101/301762 — plant biology — Posted on 2018-04-16

1056 Evidence for a reversal of the neural information flow between object perception and object reconstruction from memory

Linde-Domingo, J.; Treder, M. S.; Kerren, C.; Wimber, M.

10.1101/300913 — neuroscience — Posted on 2018-04-16

1057 Electrophysiological characterization and MCH/orexin neuronal distribution in the lateral hypothalamus of naked mole-rats (Heterocephalus glaber)

Husson, Z.; Apergis-Schoute, J.; Smith, E.

10.1101/299818 — neuroscience — Posted on 2018-04-16

1058 Identification of Significant Computational Building Blocks through Comprehensive Deep Dive of NGS Secondary Analysis Methods

Vasimuddin, M.; Misra, S.; Aluru, S.

10.1101/301903 — genomics — Posted on 2018-04-16

1059 NAD(P)HX repair deficiency causes central metabolic perturbations in yeast and human cells

Becker-Kettern, J.; Paczia, N.; Conrotte, J.-F.; Zhu, C.; Fiehn, O.; Jung, P. P.; Steinmetz, L. M.; Linster, C. L.

10.1101/302257 — biochemistry — Posted on 2018-04-16

1060 Multimerization of HIV-1 integrase hinges on conserved SH3-docking platforms

Galilee, M.; Alian, A.

10.1101/301721 — biochemistry — Posted on 2018-04-16

1061 Early Exposure to Polycyclic Aromatic Hydrocarbons (PAHs) and Cardiac Toxicity in a Species (Xenopus laevis) with Low Aryl Hydrocarbon Receptor (AHR) Responsiveness

Sestak, M. C.; Pinette, J. A.; Lamoureux, C. M.; Whittemore, S. L.

10.1101/301846 — pharmacology and toxicology — Posted on 2018-04-16

1062 Phylogenomics reveals dynamic evolution of fungal nitric oxide reductases and their relationship to secondary metabolism

Higgins, S. A.; Schadt, C. W.; Matheny, P. B.; Löffler, F. E.

10.1101/301895 — microbiology — Posted on 2018-04-16

1063 Phenomic selection: a low-cost and high-throughput alternative to genomic selection

Rincent, R.; Charpentier, J.-P.; Faivre-Rampant, P.; Paux, E.; Le Gouis, J.; Bastien, C.; Segura, V.

10.1101/302117 — genetics — Posted on 2018-04-16

1064 Antagonistic pleiotropy is unexpectedly rare in new mutations

Sane, M.; Miranda, J. J.; Agashe, D.

10.1101/301754 — evolutionary biology — Posted on 2018-04-16

1065 Sparse reduced-rank regression for exploratory visualization of single cell patch-seq recordings

Kobak, D.; Weis, M. A.; Berens, P.

10.1101/302208 — bioinformatics — Posted on 2018-04-16

1066 UROPA GUI: A web platform for genomic region annotation

Schultheis, H.; Preussner, J.; Fust, A.; Bentsen, M.; Kuenne, C.; Looso, M.

10.1101/302091 — bioinformatics — Posted on 2018-04-16

1067 Structural insights into DNA sequence recognition by Arabidopsis ETHYLENE RESPONSE FACTOR 96

Chen, C.-Y.; Lin, P.-H.; Chen, K.-H.; Cheng, Y.-S.

10.1101/302299 — plant biology — Posted on 2018-04-16

1068 Pupil responses as indicators of value-based decision-making

Van Slooten, J. C.; Jahfari, S.; Knapen, T.; Theeuwes, J.

10.1101/302166 — neuroscience — Posted on 2018-04-16

1069 Computational-Observer Analysis of Illumination Discrimination

Ding, X.; Radonjic, A.; Cottaris, N. P.; Jiang, H.; Wandell, B. A.; Brainard, D.

10.1101/302315 — neuroscience — Posted on 2018-04-16

1070 Cycle-by-cycle analysis of neural oscillations

Cole, S. R.; Voytek, B.

10.1101/302000 — neuroscience — Posted on 2018-04-16

1071 Timing Determines Tuning: a Rapid Spatiotemporal Transformation in Superior Colliculus Neurons During Reactive Gaze Shifts.

Sadeh, M.; Sajad, A.; Wang, H.; Yan, X.; Crawford, J. D.

10.1101/302125 — neuroscience — Posted on 2018-04-16

1072 The evolutionary traceability of proteins

Jain, A.; von Haeseler, A.; Ebersberger, I.

10.1101/302109 — evolutionary biology — Posted on 2018-04-16

1073 A method for RNA structure prediction shows evidence for structure in lncRNAs

Delli Ponti, R.; Armaos, A.; Marti, S.; Tartaglia, G. G.

10.1101/284869 — bioinformatics — Posted on 2018-04-16

1074 Evolutionary dynamics of multiple games

Revathi Venkateswaran, V.; S. Gokhale, C.

10.1101/302265 — evolutionary biology — Posted on 2018-04-16

1075 Cre/lox-controlled spatio-temporal perturbation of FGF signaling in zebrafish

Kirchgeorg, L.; Felker, A.; Chiavacci, E.; Mosimann, C.

10.1101/302174 — developmental biology — Posted on 2018-04-16

1076 NDUFAB1 Protects Heart by Coordinating Mitochondrial Respiratory Complex and Supercomplex Assembly

Hou, T.; Zhang, R.; Jian, C.; Ding, W.; Wang, Y.; Ma, Q.; Hu, X.; Cheng, H.; Wang, X.

10.1101/302281 — cell biology — Posted on 2018-04-16

1077 Actin filaments regulate microtubule growth at the centrosome.

Thery, M.; Inoue, D.; Obino, D.; Farina, F.; Gaillard, J.; Guerin, C.; Blanchoin, L.; Lennon-Dumenil, A.-M.

10.1101/302190 — cell biology — Posted on 2018-04-16

1078 Structures of filaments from Pick’s disease reveal a novel tau protein fold

Falcon, B.; Zhang, W.; Murzin, A. G.; Murshudov, G.; Garringer, H. J.; Vidal, R.; Crowther, R. A.; Ghetti, B.; Scheres, S.; Goedert, M.

10.1101/302216 — biophysics — Posted on 2018-04-16

1079 Concurrent processes set E. coli cell division

Micali, G.; Grilli, J.; Osella, M.; Cosentino Lagomarsino, M.

10.1101/301671 — cell biology — Posted on 2018-04-16

1080 Charge fluctuation effects on the shape of flexible polyampholytes with applications to Intrinsically disordered proteins

Thirumalai, D.; Samanta, H.

10.1101/301911 — biophysics — Posted on 2018-04-16

1081 Routine Determination of Ice Thickness for Cryo-EM Grids

Rice, W. J.; Cheng, A.; Noble, A. J.; Eng, E. T.; Kim, L. Y.; Carragher, B.; Potter, C. S.

10.1101/302018 — biophysics — Posted on 2018-04-16

1082 Stress relaxation in epithelial monolayers is controlled by actomyosin

Khalilgharibi, N.; Fouchard, J.; Asadipour, N.; Yonis, A.; Harris, A.; Mosaffa, P.; Fujita, Y.; Kabla, A.; Baum, B.; Munoz, J. J.; Miodownik, M.; Charras, G.

10.1101/302158 — biophysics — Posted on 2018-04-16

1083 Long non-coding RNAs in wild wheat progenitors

Pieri, A.; Pe, M. E.; Bertolini, E.

10.1101/301804 — plant biology — Posted on 2018-04-15

1084 SLC6A4 binding site and acute prosocial effects of (+/-)-3,4-methylendioxymethamphetamine (MDMA) are evolutionarily conserved in Octopus bimaculoides.

Dolen, G.; Edsinger, E.

10.1101/301192 — evolutionary biology — Posted on 2018-04-15

1085 Spotting the path that leads nowhere: Modulation of human theta and alpha oscillations induced by trajectory changes during navigation

Javadi, A.-H.; Patai, E. Z.; Margois, A.; Tan, H.-R.; Kumaran, D.; Nardini, M.; Penny, W.; Duzel, E.; Dayan, P.; Spiers, H.

10.1101/301697 — neuroscience — Posted on 2018-04-15

1086 Metagenomic next-generation sequencing reveals Miamiensis avidus (Ciliophora: Scuticociliatida) in the 2017 epizootic of leopard sharks (Triakis semifasciata) in San Francisco Bay, California

Retallack, H.; Okihiro, M. S.; Britton, E.; Van Sommeran, S.; DeRisi, J. L.

10.1101/301556 — microbiology — Posted on 2018-04-15

1087 Epigenetic changes induced by Bacteroides fragilis toxin

Allen, J.; Hao, S.; Sears, C. L.; Timp, W.

10.1101/301374 — genomics — Posted on 2018-04-15

1088 Coordinating the in vivo processes for minicircle production - a novel approach to large scale manufacturing

Mayrhofer, P.; Jug, H.; Strancar, A.; Di Paolo, A.; Jost, L.; Zimmermann, A.; Redl, H.

10.1101/300236 — bioengineering — Posted on 2018-04-15

1089 Measuring single neuron visual receptive field sizes by fMRI

Keliris, G. A.; Li, Q.; Papanikolaou, A.; Logothetis, N. K.; Smirnakis, S. M.

10.1101/301648 — neuroscience — Posted on 2018-04-15

1090 Wanting to like: Motivation influences behavioral and neural responses to social feedback

Hughes, B. L.; Leong, J. K.; Shiv, B.; Zaki, J.

10.1101/300657 — neuroscience — Posted on 2018-04-15

1091 Functional characterization of sensory neuron membrane proteins (SNMPs)

Zhang, H.-J.; Xu, W.; Sun, L.-N.; Chen, Q.; Anderson, A.; Xia, Q.; Papanicolaou, A.

10.1101/262154 — molecular biology — Posted on 2018-04-15

1092 Consensus assessment of the contamination level of publicly available cyanobacterial genomes

Cornet, L.; Meunier, L.; Van Vlierberghe, M.; R. Leonard, R.; Durieu, B.; Lara, Y.; Misztak, A.; Sirjacobs, D.; J. Javaux, E.; Philippe, H.; Wilmotte, A.; Baurain, D.

10.1101/301788 — genomics — Posted on 2018-04-15

1093 Pattern-Driven Navigation in 2D Multiscale Visual Spaces with Scalable Insets

Lekschas, F.; Behrisch, M.; Bach, B.; Kerpedjiev, P.; Gehlenborg, N.; Pfister, H.

10.1101/301036 — bioinformatics — Posted on 2018-04-15

1094 Naked mole-rat cortical neurons are resistant to acid-induced cell death

Husson, Z.; Smith, E. S. J.

10.1101/260901 — neuroscience — Posted on 2018-04-15

1095 Science podcasts: analysis of global production and output from 2004 to 2018

MacKenzie, L. E.

10.1101/298356 — scientific communication and education — Posted on 2018-04-15

1096 A revised understanding of Tribolium morphogenesis further reconciles short and long germ development

Benton, M. A.

10.1101/232751 — developmental biology — Posted on 2018-04-15

1097 Quantifying configuration-sampling error in Langevin simulations of complex molecular systems

Fass, J.; Sivak, D.; Crooks, G. E.; Beauchamp, K. A.; Leimkuhler, B.; Chodera, J.

10.1101/266619 — biophysics — Posted on 2018-04-15

1098 Integrin α6 and EGFR Signaling Converge at Mechanosensitive Calpain 2

Schwartz, A. D.; Hall, C. L.; Barney, L. E.; Babbitt, C. C.; Peyton, S. R.

10.1101/164525 — bioengineering — Posted on 2018-04-15

1099 IMMAN: an R/Bioconductor package for Inter-olog protein network reconstruction, Mapping and Mining ANalysis

Nickchi, P.; Jahangiri-Tazehkand, S.; Ashtinai, M.; Safari, A.; Mirzaie, M.; Jafari, M.

10.1101/069104 — systems biology — Posted on 2018-04-15

1100 Phylogenetic profiling identifies glucosyl-phosphoryl dolichol scramblase candidates

Skrabanek, L.; Menon, A. K.

10.1101/209106 — cell biology — Posted on 2018-04-15

1101 mHi-C: robust leveraging of multi-mapping reads in Hi-C analysis

Zheng, Y.; Ay, F.; Keles, S.

10.1101/301705 — genomics — Posted on 2018-04-15

1102 emeraLD: Rapid Linkage Disequilibrium Estimation with Massive Data Sets

Quick, C.; Fuchsberger, C.; Taliun, D.; Abecasis, G.; Boehnke, M.; Kang, H. M.

10.1101/301366 — bioinformatics — Posted on 2018-04-15

1103 Rational design of a compact CRISPR-Cas9 activator for AAV- mediated delivery

Vora, S.; Cheng, J.; Xiao, R.; VanDusen, N. J.; Quintino, L.; Pu, W. T.; Vandenberghe, L. H.; Chavez, A.; Church, G.

10.1101/298620 — synthetic biology — Posted on 2018-04-15

1104 A zero percent plastic ingestion rate by silver hake (Merluccius bilinearis) from the south coast of Newfoundland, Canada

Liboiron, F.; Ammendolia, J.; Saturno, J.; Melvine, J.; Zahara, A.; Richard, N.; Liboiron, M.

10.1101/301630 — ecology — Posted on 2018-04-14

1105 Sensory domain of the cell cycle kinase CckA in Caulobacter crescentus regulates the differential DNA binding activity of the master regulator CtrA

Narayanan, S.; Kumar, L.; Radhakrishnan, S. K.

10.1101/300178 — microbiology — Posted on 2018-04-14

1106 Uncovering the drivers of host-associated microbiota with joint species distribution modeling

Björk, J. R.; Hui, F. K. C.; O'Hara, R. B.; Montoya, J. M.

10.1101/137943 — microbiology — Posted on 2018-04-14

1107 Integrated proteogenomic analysis of metastatic thoracic tumors identifies APOBEC mutagenesis and copy number alterations as drivers of proteogenomic tumor evolution and heterogeneity

Roper, N.; Gao, S.; Maity, T. K.; Banday, A. R.; Zhang, X.; Venugopalan, A.; Cultraro, C. M.; Patidar, R.; Sindiri, S.; Goncearenco, A.; Panchenko, A. R.; Biswas, R.; Thomas, A.; Rajan, A.; Carter, C. A.; Kleiner, D.; Hewitt, S.; Khan, J.; Prokunina-Olsson, L.; Guha, U.

10.1101/301390 — cancer biology — Posted on 2018-04-14

1108 Schizophrenia-related cognitive dysfunction in the Cyclin-D2 knockout mouse model of ventral hippocampal hyperactivity

Grimm, C. M.; Aksamaz, S.; Schulz, S.; Teutsch, J.; Sicinski, P.; Liss, B.; Kaetzel, D.

10.1101/301226 — animal behavior and cognition — Posted on 2018-04-14

1109 The genetic architecture of shoot and root trait divergence between upland and lowland ecotypes of a perennial grass.

Khasanova, A.; Lovell, J. T.; Bonnette, J. E.; Jenkins, J.; Yoshinaga, Y.; Schmutz, J.; Juenger, T. E.

10.1101/301531 — plant biology — Posted on 2018-04-14

1110 Investigating the neuroprotective effect of AAV-mediated β-synuclein overexpression in a transgenic model of synucleinopathy

Sargent, D.; Betemps, D.; Drouyer, M.; Verchere, J.; Gaillard, D.; Arsac, J.-N.; Lakhdar, L.; Salvetti, A.; Baron, T.

10.1101/300822 — neuroscience — Posted on 2018-04-14

1111 The polar localization hub protein PopZ restrains adaptor dependent ClpXP proteolysis in Caulobacter crescentus

Joshi, K. K.; Chien, P.

10.1101/301606 — microbiology — Posted on 2018-04-14

1112 Correlation among antibiotic resistance and virulence traits in human gut microbiomes

Escudeiro, P.; Pothier, J.; Dionisio, F.; Nogueira, T.

10.1101/298190 — genomics — Posted on 2018-04-14

1113 MicroRNA-205 affects mouse granulosa cell apoptosis and estradiol synthesis by targeting CREB1

Pengju, Z.; Jun, W.; Hongyan, L.; Weixia, W.; Xiaohui, L.; Haiyan, L.; Chengcheng, T.; Xintao, L.; Yumin, Z.; Xinghong, W.

10.1101/301523 — evolutionary biology — Posted on 2018-04-14

1114 Evaluation and optimization of the protocols for measuring cytochrome P450 activity in aphids

Cao, H.-H.; Liu, T.-X.

10.1101/299545 — biochemistry — Posted on 2018-04-14

1115 Lon recognition of the replication initiator DnaA is not confined to a single degron

Liu, J.; Francis, L.; Chien, P.

10.1101/301655 — biochemistry — Posted on 2018-04-14

1116 Computational assessment of arrhythmia potential in the heterogeneously perfused ventricle

Kharche, S. R.; McIntyre, C. W.

10.1101/301614 — biophysics — Posted on 2018-04-14

1117 Evolved sequence features within the intrinsically disordered tail influence FtsZ assembly and bacterial cell division

Cohan, M. C.; Posey, A. E.; Grigsby, S. J.; Mittal, A.; Holehouse, A. S.; Buske, P. J.; Levin, P. A.; Pappu, R. V.

10.1101/301622 — biophysics — Posted on 2018-04-14

1118 Computational assessment of blood flow heterogeneity in dialysis patients’ cardiac ventricles

Kharche, S. R.; So, A.; Salerno, F.; Lee, T.-Y.; Ellis, C.; Goldman, D.; McIntyre, C. W.

10.1101/301572 — biophysics — Posted on 2018-04-14

1119 A population-based human enCYCLOPedia for circadian medicine

Ruben, M. D.; Wu, G.; Smith, D. F.; Schmidt, R. E.; Francey, L. J.; Anafi, R. C.; Hogenesch, J. B.

10.1101/301580 — bioinformatics — Posted on 2018-04-14

1120 Optimum Search Schemes for Approximate String Matching Using Bidirectional FM-Index

Kianfar, K.; Pockrandt, C.; Torkamandi, B.; Luo, H.; Reinert, K.

10.1101/301085 — bioinformatics — Posted on 2018-04-14

1121 The roles of vision and antennal mechanoreception in hawkmoth flight control.

Dahake, A.; Stoeckl, A.; Foster, J.; Sane, S. P.; Kelber, A.

10.1101/222448 — neuroscience — Posted on 2018-04-14

1122 Uncovering the drivers of host-associated microbiota with joint species distribution modeling

Björk, J. R.; Hui, F. K. C.; O'Hara, R. B.; Montoya, J. M.

10.1101/137943 — microbiology — Posted on 2018-04-14

1123 Bayesian model comparison for rare variant association studies of multiple phenotypes

DeBoever, C.; Aguirre, M.; Tanigawa, Y.; Spencer, C. C. A.; Poterba, T.; Bustamante, C. D.; Daly, M. J.; Pirinen, M.; Rivas, M. A.

10.1101/257162 — genetics — Posted on 2018-04-14

1124 Parental neural responsivity to infants visual attention: how mature brains scaffold immature brains during social interaction.

Wass, S. V.; Noreika, V.; Georgieva, S.; Clackson, K.; Brightman, L.; Nutbrown, R.; Santamaria, L.; Leong, V.

10.1101/295790 — neuroscience — Posted on 2018-04-14

1125 Pervasive hybridizations in the history of wheat relatives

Glemin, S.; Scornavacca, C.; Dainat, J.; Burgarella, C.; Viader, V.; Ardisson, M.; Sarah, G.; Santoni, S.; David, J.; Ranwez, V.

10.1101/300848 — evolutionary biology — Posted on 2018-04-14

1126 Within-subject combination of diffusion tensor MRI and CLARITY reveals alterations in the social brain network resulting from α-neurexin II deletion

Pervolaraki, E.; Tyson, A. L.; Pibiri, F.; Poulter, S. L.; Reichelt, A. C.; Rodgers, R. J.; Clapcote, S. J.; Lever, C.; Andreae, L. C.; Dachtler, J.

10.1101/300806 — neuroscience — Posted on 2018-04-14

1127 Complementary information on single nucleotide variants, INDELs and functional translocations can be obtained with RNAseq using different library preparations

Panero, R.; Arigoni, M.; Olivero, M.; Cordero, F.; Weisz, A.; Beccuti, M.; Direnzo, M. F.; Calogero, R. A.

10.1101/301010 — genomics — Posted on 2018-04-14

1128 Loss of charge at solvent exposed Lys residues does not induce the aggregation of superoxide dismutase 1

Crosby, K.; Crown, A. M.; Roberts, B. L.; Brown, H.; Ayers, J. I.; Borchelt, D.

10.1101/301309 — biochemistry — Posted on 2018-04-14

1129 TP53I11 Suppresses Extracellular Matrix-independent Survival and Mesenchymal Transition in Mammary Epithelial Cells

Xiao, T.; Zhang, H.; zhou, Y.; Geng, J.; Xu, Z.; Liang, Y.; Qiao, H.; Suo, G.

10.1101/301499 — molecular biology — Posted on 2018-04-14

1130 Directed evolution of Escherichia coli with lower-than-natural plasmid mutation rates

Deatherage, D. E.; Leon, D.; Rodriguez, A. E.; Omar, S. K.; Barrick, J. E.

10.1101/301382 — evolutionary biology — Posted on 2018-04-14

1131 Comment on ‘Multiple Origin but Single Domestication Led to Oryza sativa’

Civan, P.; Brown, T. A.

10.1101/299669 — evolutionary biology — Posted on 2018-04-14

1132 Intrinsic cooperativity potentiates parallel cis-regulatory evolution

Sorrells, T. R.; Johnson, A. N.; Howard, C. J.; Britton, C. S.; Fowler, K. R.; Feigerle, J. T.; Weil, P. A.; Johnson, A. D.

10.1101/301234 — evolutionary biology — Posted on 2018-04-14

1133 E proteins differentially co-operate with proneural bHLH transcription factors to sharpen neurogenesis

Le Dreau, G.; Escalona, R.; Fueyo, R.; Herrera, A.; Martinez, J. D.; Usieto, S.; Menendez, A.; Pons, S.; Martinez-Balbas, M. A.; Marti, E.

10.1101/301093 — developmental biology — Posted on 2018-04-14

1134 Contribution of the endosomal-lysosomal and proteasomal systems in Amyloid-β Precursor Protein derived fragments processing

Evrard, C.; Kienlen-Campard, P.; Opsomer, R.; Tasiaux, B.; Octave, J.-N.; Buee, L.; Sergeant, N.; Vingtdeux, V.

10.1101/300921 — neuroscience — Posted on 2018-04-14

1135 The Use of Visual Cues in Gravity Judgements on Parabolic Motion.

Joerges, B.; Slupinski, L.; Lopez-Moliner, J.

10.1101/301077 — neuroscience — Posted on 2018-04-14

1136 B cell receptor crosslinking can augment T cell help-mediated germinal center B cell selection.

Turner, J. S.; Ke, F.; Grigorova, I. L.

10.1101/300939 — immunology — Posted on 2018-04-14

1137 npphen: an R-package for non-parametric reconstruction of vegetation phenology and anomaly detection using remote sensing

Estay, S. A.; Chavez, R.

10.1101/301143 — ecology — Posted on 2018-04-14

1138 The E3 ubiquitin ligase MIB-1 is necessary to form the nuclear halo in C. elegans sperm

Herrera, L. A.; Starr, D. A.

10.1101/301291 — developmental biology — Posted on 2018-04-14

1139 Learning and Imputation for Mass-spec Bias Reduction (LIMBR)

Crowell, A. M.; Greene, C. S.; Loros, J. J.; Dunlap, J. C.

10.1101/301242 — bioinformatics — Posted on 2018-04-14

1140 Searching Algorithm for Type IV Effector proteins (S4TE) 2.0: improved tools for type IV effector prediction, analysis and comparison

Noroy, C.; Lefrancois, T.; Meyer, D. F.

10.1101/301150 — bioinformatics — Posted on 2018-04-14

1141 Dynamic modeling of Streptococcus pneumoniae competence provides regulatory mechanistic insights

Weyder, M.; Prudhomme, M.; Berge, M.; Polard, P.; Fichant, G.

10.1101/300814 — systems biology — Posted on 2018-04-14

1142 Representation of natural image contents by sparsely active neurons in visual cortex

Yoshida, T.; Ohki, K.

10.1101/300863 — neuroscience — Posted on 2018-04-14

1143 Autoregulation of the S. mutans SloR metalloregulator is constitutive and driven by an independent promoter

Monette, P.; Brach, R.; Cowan, A.; Winters, R.; Weisman, J.; Seybert, F.; Goguen, K.; Chen, J.; Glasfeld, A.; Spatafora, G. A.

10.1101/301416 — microbiology — Posted on 2018-04-14

1144 Feammox Acidimicrobiaceae bacterium A6, a lithoautotrophic electrode-colonizing bacterium

Ruiz-Urigüen, M.; Shuai, W.; Jaffe, P. R.

10.1101/300731 — microbiology — Posted on 2018-04-14

1145 Vitexin alters Staphylococcus aureus surface hydrophobicity to interfere with biofilm formation.

Das, M. C.; Das, A.; Samaddar, S.; Daware, A.; Ghosh, C.; Acharjee, S.; Sandhu, P.; Jawed, J. J.; De, U. C.; Majumdar, S.; Das Gupta, S. K.; Akhter, Y.; Bhattacharjee, S.

10.1101/301473 — microbiology — Posted on 2018-04-14

1146 Brucella Peptide Cross-Reactive MHC I Presentation Activates SIINFEKL-Specific TCR Expressing T Cells

Harms, J. S.; Khan, M.; Hall, C.; Splitter, G. A.; Homan, E. J.; Bremel, R. D.; Smith, J.

10.1101/301465 — immunology — Posted on 2018-04-14

1147 Visualizing Wnt secretion from endoplasmic reticulum to filopodia

Moti, N.; Yu, J.; Boncompain, G.; Perez, F.; Virshup, D. M.

10.1101/271684 — cell biology — Posted on 2018-04-14

1148 Microevolution of aquatic Streptococcus agalactiae ST-261 from Australia indicates dissemination via imported tilapia and ongoing adaptation to marine hosts or environment

Kawasaki, M.; Delamare-Deboutteville, J.; Bowater, R.; Walker, M. J.; Beatson, S. A.; Ben Zakour, N.; Barnes, A. C.

10.1101/301424 — bioinformatics — Posted on 2018-04-14

1149 The influence of the supramolecular complex PRE -1 on permeability of membranes of mitochondria.

Mardieva, K.; Burkhanova, M.

10.1101/300855 — biochemistry — Posted on 2018-04-14

1150 Whole genome sequence analysis of 91 Salmonella Enteritidis isolates from mice caught on poultry farms in the mid 1990s

Guard, J.; Cao, G.; Luo, Y.; Baugher, J. D.; Davison, S.; Yao, K.; Hoffmann, M.; Zhang, G.; Bell, R. L.; Zheng, J.; Brown, E.; Allard, M. W.

10.1101/301432 — genomics — Posted on 2018-04-14

1151 MGDb: An analyzed database and a genomic resource of mango (Mangifera Indica L.) cultivars for mango research

Islam, T. Q.-u.; Khan, A. M.; Faizan, R.; Mahmood, U.

10.1101/301358 — bioinformatics — Posted on 2018-04-14

1152 Vms1p is a release factor for the Ribosome-associated Quality control Complex

Rendon, O. Z.; Fredrickson, E. K.; Howard, C. J.; Vranken, J. V.; Fogarty, S.; Tolley, N. D.; Kalia, R.; Osuna, B. A.; Shen, P. S.; Hill, C. P.; Frost, A.; Rutter, J.

10.1101/301341 — biochemistry — Posted on 2018-04-14

1153 Fermentation characteristics of mead and wine generated by yeasts isolated from beehives of two Austrian regions

Gangl, H.; Lopandic, K.; Tscheik, G.; Mandl, S.; Leitner, G.; Wechselberger, K.; Batusic, M.; Tiefenbrunner, W.

10.1101/300780 — microbiology — Posted on 2018-04-13

1154 Effects of duplicated mapped read PCR artifacts on RNA-seq differential expression analysis based on qRNA-seq

Salzberg, A. C.; Hu, J.; Conroy, E. J.; Cladel, N. M.; Brucklacher, R. B.; Bixler, G. B.; Imamura Kawasawa, Y.

10.1101/301259 — genomics — Posted on 2018-04-13

1155 Single cell RNA-seq denoising using a deep count autoencoder

Eraslan, G.; Simon, L. M.; Mircea, M.; Mueller, N. S.; Theis, F. J.

10.1101/300681 — bioinformatics — Posted on 2018-04-13

1156 Identification of protein abundance changes in biopsy-level hepatocellular carcinoma tissues using PCT-SWATH

Zhu, Y.; Zhu, J.; Lu, C.; Sun, P.; Xie, W.; Zhang, Q.; Liang, Y.; zhu, t.; Ruan, G.; Aebersold, R.; Hunag, S.; Guo, T.

10.1101/300673 — systems biology — Posted on 2018-04-13

1157 Epigenetic regulation of the circadian gene Per1 in the hippocampus mediates age-related changes in memory and synaptic plasticity

Kwapis, J. L.; Alaghband, Y.; Kramar, E. A.; Lopez, A. J.; Vogel Ciernia, A.; White, A. O.; Shu, G.; Rhee, D.; Michael, C. M.; Montellier, E.; Liu, Y.; Magnan, C. N.; Sassone-Corsi, P.; Baldi, P.; Matheos, D. P.; Wood, M. A.

10.1101/301135 — neuroscience — Posted on 2018-04-13

1158 Co-regulation of alternative splicing by hnRNPM and ESRP1 during EMT

Harvey, S.; Xu, Y.; Lin, X.; Gao, X. D.; Qiu, Y.; Ahn, J.; Xiao, X.; Cheng, C.

10.1101/301267 — molecular biology — Posted on 2018-04-13

1159 Taxa-driven functional shifts associated with stormflow in an urban stream microbial community

Chaudhary, A.; Kauser, I.; Ray, A.; Poretsky, R.

10.1101/300699 — microbiology — Posted on 2018-04-13

1160 RAB-35 aids apoptotic cell clearance by regulating cell corpse recognition and phagosome maturation

Haley, R.; Wang, Y.; Zhou, Z.

10.1101/298380 — genetics — Posted on 2018-04-13

1161 Required marker properties for unbiased estimates of the genetic correlation between populations

Wientjes, Y.; Calus, M. P. L.; Duenk, P.; Bijma, P.

10.1101/301333 — genetics — Posted on 2018-04-13

1162 Influence of hyaluronic acid transitions in tumor microenvironment on glioblastoma malignancy and invasive behavior

Chen, J.-W. E.; Pedron, S.; Shyu, P.; Hu, Y.; Sarkaria, J. N.; Harley, B.

10.1101/291898 — bioengineering — Posted on 2018-04-13

1163 Centenarian Controls Increase Variant Effect-sizes by an average two-fold in an Extreme Case-Extreme Control Analysis of Alzheimer’s Disease

Tesi, N.; van der Lee, S. J.; Hulsman, M.; Jansen, I. E.; Stringa, N.; van Schoor, N.; Meijers-Heijboer, H.; Huisman, M.; Scheltens, P.; Reinders, M. J. T.; van der Flier, W. M.; Holstege, H.

10.1101/298018 — genetics — Posted on 2018-04-13

1164 Controlled cycling and quiescence enables homology directed repair in engraftment-enriched adult hematopoietic stem and progenitor cells

Shin, J.; Wyman, S. K.; DeWitt, M. A.; Bray, N. L.; Vu, J.; Corn, J.

10.1101/301176 — cell biology — Posted on 2018-04-13

1165 One prophage WO gene rescues cytoplasmic incompatibility in Drosophila melanogaster

Shropshire, D.; On, J.; Layton, E. M.; Zhou, H.; Bordenstein, S. R.

10.1101/300269 — genetics — Posted on 2018-04-13

1166 What does not kill a tumour may make it stronger: in silico Insights into Chemotherapeutic Drug Resistance

Hamis, S.; Nithiarasu, P.; Powathil, G.

10.1101/230318 — cancer biology — Posted on 2018-04-13

1167 Pervasive chromatin remodeling at X-inactivation escape genes in schizophrenic males

Hegyi, H.; Hassan, H.

10.1101/300624 — neuroscience — Posted on 2018-04-13

1168 Mono-homologous linear DNA recombination by the non-homologous end-joining pathway as a novel and simple gene inactivation method: a proof of concept study in Dietzia sp. DQ12-45-1b

Lu, S.; Nie, Y.; Wang, M.; Xu, H.; Ma, D.; Liang, J.-L.; Wu, X.-L.

10.1101/300723 — microbiology — Posted on 2018-04-13

1169 Precise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins

Pogorelyy, M. V.; Minervina, A. A.; Puelma Touzel, M.; Sycheva, A. L.; Komech, E. A.; Kovalenko, E. I.; Karganova, G. G.; Egorov, E. S.; Komkov, A. Y.; Chudakov, D. M.; Mamedov, I. Z.; Mora, T.; Walczak, A.; Lebedev, Y. B.

10.1101/300343 — immunology — Posted on 2018-04-13

1170 A Single-Cell Atlas of Cell Types, States, and Other Transcriptional Patterns from Nine Regions of the Adult Mouse Brain

Saunders, A.; Macosko, E.; Wysoker, A.; Goldman, M.; Krienen, F.; de Rivera, H.; Bien, E.; Baum, M.; Wang, S.; Goeva, A.; Nemesh, J.; Kamitaki, N.; Brumbaugh, S.; Kulp, D.; McCarroll, S. A.

10.1101/299081 — neuroscience — Posted on 2018-04-13

1171 Phase Separations Driven by RNA Scaffolds and Protein Sequestration in FXTAS

Botta-Orfila, T.; Cid-Samper, F.; Gelabert-Baldrich, I.; Lang, B.; Lorenzo-Gotor, N.; Delli Ponti, R.; WFM Severijnen, L.-A.; Bolognesi, B.; Gelpi, E.; Hukema-Felten, R. K.; Tartaglia, G. G.

10.1101/298943 — molecular biology — Posted on 2018-04-13

1172 Fresh Snowfall Microbiology and Chemistry are Driven by Geography in Storm-Tracked Events

Spear, J. R.; Honeyman, A. S.; Day, M. L.

10.1101/300772 — microbiology — Posted on 2018-04-13

1173 Connectivity Problems on Heterogeneous Graphs

Wu, J.; Khodaverdian, A.; Weitz, B.; Yosef, N.

10.1101/300012 — bioinformatics — Posted on 2018-04-13

1174 Nicotinic modulation of hierarchal inhibitory control over prefrontal cortex resting state dynamics: modeling of genetic modification and schizophrenia-related pathology

Rooy, M.; Koukouli, F.; Maskos, U.; Gutkin, B.

10.1101/301051 — systems biology — Posted on 2018-04-13

1175 YggG is a Novel SPI-1 Effector Essential for Salmonella Virulence

Li, M.; Gu, B.; Bomjan, R.; Chitale, M.; Kihar, D.; Zhou, D.

10.1101/300152 — microbiology — Posted on 2018-04-13

1176 Imprint of Assortative Mating on the Human Genome

Yengo, L.; Robinson, M. R.; Keller, M. C.; Kemper, K. E.; Yang, Y.; Trzaskowski, M.; Gratten, J.; Turley, P.; Cesarini, D.; Benjamin, D. J.; Wray, N. R.; Yang, J.; Goddard, M. E.; Visscher, P. M.

10.1101/300020 — genetics — Posted on 2018-04-13

1177 Mathematical and ecological traits of above and below ground biomass production of beech (Fagus silvatica L.) trees growing in pure even-aged stands in north-east France

Le Goff, N.; Ottorini, J.-M.

10.1101/300210 — ecology — Posted on 2018-04-13

1178 Trypanosomes have divergent kinesin-2 proteins that function differentially in IFT, cell division, and motility

Douglas, R. L.; Haltiwanger, B. M.; Wu, H.; Jeng, R. L.; Mancuso, J.; Cande, W. Z.; Welch, M. D.

10.1101/301127 — cell biology — Posted on 2018-04-13

1179 CAMISIM: Simulating metagenomes and microbial communities

Fritz, A.; Hofmann, P.; Majda, S.; Dahms, E.; Droege, J.; Fiedler, J.; Lesker, T. R.; Belmann, P.; DeMaere, M. Z.; Darling, A. E.; Sczyrba, A.; Bremges, A.; McHardy, A. C.

10.1101/300970 — bioinformatics — Posted on 2018-04-13

1180 Integrated fusible alloy microelectrodes based microfluidic impedance cytometry for cell-in-droplet quantification

Panwar, J.; Roy, R.

10.1101/278069 — bioengineering — Posted on 2018-04-13

1181 GNE: A deep learning framework for gene network inference by aggregating biological information

KC, K.; Li, R.; Cui, F.; Haake, A.

10.1101/300996 — systems biology — Posted on 2018-04-13

1182 Persistent coding of outcome-predictive cue features in the rat nucleus accumbens

Gmaz, J. M.; Carmichael, J. E.; van der Meer, M.

10.1101/300251 — neuroscience — Posted on 2018-04-13

1183 An important role for periplasmic storage in Pseudomonas aeruginosa copper homeostasis revealed by a combined experimental and computational modeling study

Parmar, J. H.; Quintana, J.; Laubenbacher, R.; Argüello, J. M.; Mendes, P.

10.1101/301002 — microbiology — Posted on 2018-04-13

1184 Spatial Mark-Resight for Categorically MarkedPopulations with an Application to GeneticCapture-Recapture

Augustine, B.; Stewart, F.; Royle, J. A.; Fisher, J.; Kelly, M.

10.1101/299982 — ecology — Posted on 2018-04-13

1185 Phyla-specific Correlated Dynamics in Tropomyosin

James, J. K.; Nanda, V.

10.1101/301028 — biophysics — Posted on 2018-04-13

1186 The molecular structure of Schistosoma mansoni PNP isoform 2 provides insights into the nucleotide selectivity of PNPs

Torini, J.; Romanello, L.; Batista, F.; Serrao, V. H.; Faheem, M.; Zeraik, A. E.; Bird, L.; Nettleship, J.; Reddivari, Y.; Owens, R.; DeMarco, R.; Borges, J. C.; Brandao-Neto, J.; Pereira, H.

10.1101/300533 — biochemistry — Posted on 2018-04-13

1187 Costless metabolic secretions as drivers of interspecies interactions in microbial ecosystems

Pacheco, A. R.; Moel, M.; Segre, D.

10.1101/300046 — systems biology — Posted on 2018-04-13

1188 Delta activity encodes taste information in the human brain

Wallroth, R.; Ohla, K.

10.1101/300194 — neuroscience — Posted on 2018-04-13

1189 Preferred hexoses influence long-term memory and induction of lactose catabolism by Streptococcus mutans

Zeng, L.; Burne, R. A.

10.1101/300749 — microbiology — Posted on 2018-04-13

1190 In Vitro and In Vivo activity of a novel catheter lock solution against bacterial and fungal biofilms

Chandra, J.; Long, L.; Isham, N.; Mukherjee, P. K.; DiSciullo, G.; Appelt, K.; Ghannoum, M. A.

10.1101/300145 — microbiology — Posted on 2018-04-13

1191 Monitoring Anti-Pythium insidiosum IgG Antibodies and (1->3)-β-D-Glucan in Vascular Pythiosis

Worasilchai, N.; Permpalung, N.; Chongsathidkiet, P.; Leelahavanichkul, A.; Mendoza, L. A.; Palaga, T.; Reantragoon, R.; Finkelman, M. A.; Sutcharitchan, P.; Chindamporn, A.

10.1101/300764 — microbiology — Posted on 2018-04-13

1192 Exosomes exploit the virus entry machinery and pathway to transmit IFN-α-induced antiviral activity.

Yao, Z.; Li, X.; Chen, J.; Qiao, Y.; Shen, F.; Shi, B.; Liu, J.; Ding, J.; Peng, L.; Li, J.; Yuan, Z.

10.1101/300715 — microbiology — Posted on 2018-04-13

1193 Performance of an IAVI-African Network of Clinical Research Laboratories in Standardized ELISpot and Peripheral Blood Mononuclear Cell Processing in Support of HIV Vaccine Clinical Trials

Langat, R.; Farah, B.; Indangasi, J.; Ogola, S.; Omosa-Manyonyi, G.; Anzala, O.; Bizimana, J.; Tekirya, E.; Ngetsa, C.; Silwamba, M.; Muyanja, E.; Chetty, P.; Jangano, M.; Hills, N.; Gilmour, J.; Dally, L.; Cox, J.; Hayes, P.

10.1101/300087 — immunology — Posted on 2018-04-13

1194 Polygenic adaptation and convergent evolution across both growth and cardiac genetic pathways in African and Asian rainforest hunter-gatherers

Bergey, C. M.; Lopez, M.; Harrison, G. F.; Patin, E.; Cohen, J.; Quintana-Murci, L.; Barreiro, L. B.; Perry, G. H.

10.1101/300574 — genomics — Posted on 2018-04-13

1195 Mapping Social Ecological Systems Archetypes

Rocha, J. C.; Malmborg, K.; Gordon, L.; Brauman, K.; DeClerk, F.

10.1101/299693 — ecology — Posted on 2018-04-13

1196 Tensorial Blind Source Separation for Improved Analysis of Multi-Omic Data

Teschendorff, A.; Han, J.; Paul, D.; Virta, J.; Nordhausen, K.

10.1101/300277 — bioinformatics — Posted on 2018-04-13

1197 Optimum Search Schemes for Approximate String Matching Using Bidirectional FM-Index

Kianfar, K.; Pockrandt, C.; Torkamandi, B.; Luo, H.; Reinert, K.

10.1101/301085 — bioinformatics — Posted on 2018-04-13

1198 A single prophage WO gene rescues cytoplasmic incompatibility in Drosophila melanogaster

Shropshire, J. D.; On, J.; Layton, E. M.; Zhou, H.; Bordenstein, S. R.

10.1101/300269 — genetics — Posted on 2018-04-13

1199 Biotic interactions limit the geographic range of an annual plant: herbivory and phenology mediate fitness beyond a range margin

Benning, J.; Eckhart, V. M.; Geber, M. A.; Moeller, D. A.

10.1101/300590 — ecology — Posted on 2018-04-13

1200 Design of Transcranial Magnetic Stimulation Coils with Optimal Trade-off between Depth, Focality, and Energy

Gomez, L.; Goetz, S.; Peterchev, A. V.

10.1101/300616 — bioengineering — Posted on 2018-04-13

1201 Enhanced bacterial immunity and mammalian genome editing via RNA polymerase-mediated dislodging of Cas9 from double strand DNA breaks.

Clarke, R.; Heler, R.; MacDougall, M. S.; Yeo, N. C.; Chavez, A.; Regan, M.; Hanakahi, L.; Church, G. M.; Marraffini, L. A.; Merrill, B.

10.1101/300962 — molecular biology — Posted on 2018-04-13

1202 ComM is a hexameric helicase that promotes branch migration during natural transformation in diverse Gram-negative species

Nero, T. M.; Dalia, T. N.; Wang, J. C.-Y.; Kysela, D. T.; Bochman, M. L.; Dalia, A. B.

10.1101/147660 — microbiology — Posted on 2018-04-13

1203 Transcranial in vivo recording of neural activity in the rodent brain with near-infrared photoacoustic voltage-sensitive dye imaging

Kang, J.; Zhang, H. K.; Kadam, S. D.; Fedorko, J.; Valentine, H.; Malla, A. P.; Yan, P.; Kang, J. U.; Rahmim, A.; Gjedde, A.; Loew, L. M.; Wong, D. F.; Boctor, E. M.

10.1101/202408 — neuroscience — Posted on 2018-04-13

1204 Collective cell behaviour in mechanosensing of substrate thickness

Tusan, C. G.; Man, Y. H.; Zarkoob, H.; Johnson, D. A.; Andriotis, O. G.; Thurner, P. J.; Yang, S.; Sander, E. A.; Gentleman, E.; Sengers, B.; Evans, N.

10.1101/228478 — biophysics — Posted on 2018-04-13

1205 Targeting redox regulatory site of protein kinase B impedes neutrophilic inflammation

Hwang, T.-L.; Chen, P.-J.; Ko, I.-L.; Lee, C.-L.; Hu, H.-C.; Chang, F.-R.; Wu, Y.-C.; Leu, Y.-L.; Wu, C.-C.; Tsai, Y.-F.; Lin, C.-Y.; Pan, C.-Y.

10.1101/264184 — pharmacology and toxicology — Posted on 2018-04-13

1206 Prefrontal cortex as a meta-reinforcement learning system

Wang, J. X.; Kurth-Nelson, Z.; Kumaran, D.; Tirumala, D.; Soyer, H.; Leibo, J. Z.; Hassabis, D.; Botvinick, M.

10.1101/295964 — neuroscience — Posted on 2018-04-13

1207 A systematic review of social contact surveys to inform transmission models of close contact infections

Hoang, T. V.; Coletti, P.; Melegaro, A.; Wallinga, J.; Grijalva, C.; Edmunds, J.; Beutels, P.; Hens, N.

10.1101/292235 — epidemiology — Posted on 2018-04-13

1208 Mass Spectra alignment using virtual lock-masses

Brochu, F.; Plante, P.-L.; Drouin, A.; Laviolette, F.; Marchand, M.; Corbeil, J.

10.1101/292425 — bioinformatics — Posted on 2018-04-13

1209 Neuropathology and cognitive performance in centenarians

Ganz, A. B.; Beker, N.; Hulsman, M.; Sikkes, S.; Netherlands Brain Bank (NBB), ; Scheltens, P.; Smit, A. B.; Rozemuller, A. J. M.; Hoozemans, J. J. M.; Holstege, H.

10.1101/298935 — neuroscience — Posted on 2018-04-13

1210 Many rice genes are differentially spliced between roots and shoots but cytokinin hormone application has minimal effect on splicing

Freese, N.; Estrada, A. D.; Blakley, I. C.; Duan, J.; Loraine, A. E.

10.1101/293217 — molecular biology — Posted on 2018-04-13

1211 Inferring identical by descent sharing of sample ancestors promotes high resolution relative detection

Ramstetter, M. D.; Shenoy, S. A.; Dyer, T. D.; Lehman, D. M.; Curran, J. E.; Duggirala, R.; Blangero, J.; Mezey, J. G.; Williams, A. L.

10.1101/243048 — genetics — Posted on 2018-04-13

1212 A potent neutralizing epitope of limited variability in the head domain of haemagglutinin as a novel influenza vaccine target

Thompson, C. P.; Lourenco, J.; Walters, A. A.; Obolski, U.; Edmans, M.; Palmer, D. S.; Kooblall, K.; Carnell, G. W.; O Connor, D.; Bowden, T. A.; Pybus, O. G.; Pollard, A. J.; Temperton, N. J.; Lambe, T.; Gilbert, S. C.; Gupta, S.

10.1101/212845 — epidemiology — Posted on 2018-04-13

1213 Complementary studies of lipid membrane dynamics using iSCAT and super-resolved Fluorescence Correlation Spectroscopy

Reina, F.; Galiani, S.; Shrestha, D.; Sezgin, E.; de Wit, G.; Cole, D.; Lagerholm, B. C.; Kukura, P.; Eggeling, C.

10.1101/235564 — biophysics — Posted on 2018-04-13

1214 An in vivo binding assay for RNA-binding proteins based on repression of a reporter gene

Katz, N.; Cohen, R.; Solomon, O.; Kaufmann, B.; Eden, N.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R.

10.1101/168625 — synthetic biology — Posted on 2018-04-13

1215 RBP-RNA interactions in the 5 UTR lead to structural changes that alter translation

Katz, N.; Cohen, R.; Solomon, O.; Kaufmann, B.; Atar, O.; Yakhini, Z.; Goldberg, S.; Amit, R.

10.1101/174888 — synthetic biology — Posted on 2018-04-13

1216 Inferring Cancer Progression from Single-cell Sequencing while Allowing Mutation Losses

Ciccolella, S.; Soto Gomez, M.; Patterson, M.; Della Vedova, G.; Hajirasouliha, I.; Bonizzoni, P.

10.1101/268243 — bioinformatics — Posted on 2018-04-13

1217 Convergent evidence for predispositonal effects of brain volume on alcohol consumption

Baranger, D. A.; Demers, C. H.; Elsayed, N. M.; Knodt, A. R.; Radtke, S. R.; Desmarais, A.; Few, L. R.; Agrawal, A.; Heath, A. C.; Barch, D. M.; Squeglia, L. M.; Williamson, D. E.; Hariri, A. R.; Bogdan, R.

10.1101/299149 — neuroscience — Posted on 2018-04-13

1218 Deleterious genetic variants in NOTCH1 are a major contributor to the incidence of non-syndromic Tetralogy of Fallot

Page, D. J.; Miossec, M. J.; Williams, S. G.; Fotiou, E.; Monaghan, R. M.; Cordell, H. J.; Sutcliffe, L.; Topf, A.; Bourgey, M.; Bourque, G.; Eveleigh, R.; Dunwoodie, S. L.; Winlaw, D. S.; Bhattacharya, S.; Breckpot, J.; Devriendt, K.; Gewillig, M.; Brook, D.; Setchfield, K.; Bu'Lock, F. A.; O'Sullivan, J.; Stuart, G.; Bezzina, C.; Mulder, B. J. M.; Postma, A. V.; Bentham, J. R.; Baron, M.; Bhaskar, S. S.; Black, G. C.; Newman, W. G.; Hentges, K. G.; Lathrop, M.; Santibanez-Koref, M.; Keavney, B. D.

10.1101/300905 — genetics — Posted on 2018-04-13

1219 Modulation of ACD6 dependent hyperimmunity by natural alleles of an Arabidopsis thaliana NLR resistance gene

Zhu, W.; Zaidem, M.; Van de Weyer, A.-L.; Gutaker, R. M.; Chae, E.; Kim, S.-T.; Bemm, F.; Li, L.; Schwab, R.; Unger, F.; Beha, M. J.; Demar, M.; Weigel, D.

10.1101/300798 — plant biology — Posted on 2018-04-13

1220 WDFY2 restrains matrix metalloprotease secretion and cell invasion by retention of VAMP3 in endosomal tubules

Sneeggen, M.; Pedersen, N. M.; Campsteijn, C.; Haugsten, E. M.; Stenmark, H.; Schink, K. O.

10.1101/299610 — cell biology — Posted on 2018-04-13

1221 Mice harboring a SCA28 patient mutation in AFG3L2 develop late-onset ataxia associated with enhanced mitochondrial proteotoxicity.

Mancini, C.; Hoxha, E.; Iommarini, L.; Brussino, A.; Richter, U.; Montarolo, F.; Cagnoli, C.; Parolisi, R.; Gondor Morosini, D. I.; Nicolo, V.; Maltecca, F.; Muratori, L.; Ronchi, G.; Geuna, S.; Arnaboldi, F.; Donetti, E.; Giorgio, E.; Cavalieri, S.; Di Gregorio, E.; Pozzi, E.; Ferrero, M.; Riberi, E.; Casari, G.; Altruda, F.; Turco, E.; Gasparre, G.; Battersby, B. J.; Porcelli, A. M.; Ferrero, E.; Brusco, A.; Tempia, F.

10.1101/300202 — genetics — Posted on 2018-04-13

1222 Circular RNA expression in human hematopoietic cells is widespread and cell-type specific

Nicolet, B. P.; Engels, S.; Aglialoro, F.; van den Akker, E.; von Lindern, M. M.; Wolkers, M. C.

10.1101/300293 — immunology — Posted on 2018-04-12

1223 Ezrin enrichment on curved membranes requires a specific conformation or interaction with a curvature-sensitive partner

Tsai, F.-C.; Bertin, A.; Bousquet, H.; Manzi, J.; Senju, Y.; Tsai, M.-C.; Picas, L.; Miserey-Lenkei, S.; Lappalainen, P.; Lemichez, E.; Coudrier, E.; Bassereau, P.

10.1101/297895 — biophysics — Posted on 2018-04-12

1224 Dilution and titration of cell-cycle regulators may control cell size in budding yeast

Heldt, F. S.; Lunstone, R.; Tyson, J. J.; Novak, B.

10.1101/300160 — systems biology — Posted on 2018-04-12

1225 Voltage gated N-type Ca-channels in Neurogliaform interneurons in the rat Prefrontal Cortex

Dalby, N. O.; Grunnet, M.

10.1101/299503 — neuroscience — Posted on 2018-04-12

1226 Modified Pearson Correlation Coefficient for Two-color Imaging in Spherocylindrical Cells

Mohapatra, S.; Weisshaar, J. C.

10.1101/300517 — biophysics — Posted on 2018-04-12

1227 Improvements to the rice genome annotation through large-scale analysis of RNA-Seq and proteomics datasets

Ren, Z.; Qi, D.; Pugh, N.; Li, K.; Wen, B.; Zhou, R.; Xu, S.; Liu, S.; Jones, A. R.

10.1101/300426 — plant biology — Posted on 2018-04-12

1228 Predicting influenza H3N2 vaccine efficacy from evolution of the dominant epitope

Bonomo, M. E.; Deem, M. W.

10.1101/300665 — immunology — Posted on 2018-04-12

1229 Catalysis of cataract-associated human γD crystallin aggregation via dynamic disulfide exchange

Serebryany, E.; Yu, S.; Trauger, S. A.; Budnik, B.; Shakhnovich, E. I.

10.1101/300608 — biochemistry — Posted on 2018-04-12

1230 Normalization models of contextualized touch

Rahman, M. S.; Yau, J. M.

10.1101/283218 — neuroscience — Posted on 2018-04-12

1231 RosettaAntibodyDesign (RAbD): A General Framework for Computational Antibody Design

Adolf-Bryfogle, J.; Kalyuzhniy, O.; Kubitz, M.; Weitzner, B. D.; Hu, X.; Adachi, Y.; Schief, W. R.; Dunbrack, R. L.

10.1101/183350 — bioengineering — Posted on 2018-04-12

1232 Genome-based transmission modeling separates imported tuberculosis from recent transmission within an immigrant population

Ayabina, D.; Ronning, J. O.; Alfsnes, K.; Debech, N.; Brynildsrud, O. B.; Arnesen, T.; Norheim, G.; Mengshoel, A.-T.; Rykkvin, R.; Dahle, U. R.; Colijn, C.; Eldholm, V.

10.1101/226662 — epidemiology — Posted on 2018-04-12

1233 In silico mouse study identifies tumor growth kinetics as biomarkers for the outcome of anti-angiogenic treatment

Wu, Q.; Arnheim, A. D.; Finley, S. D.

10.1101/300566 — systems biology — Posted on 2018-04-12

1234 Hyper-excitability and hyper-plasticity disrupt cerebellar signal transfer in the IB2 KO mouse model of autism

D'Angelo, E. U.; Soda, T.; Mapelli, L.; Locatelli, F.; Botta, L.; Goldfarb, M.; Prestori, F.

10.1101/300228 — neuroscience — Posted on 2018-04-12

1235 Translation elongation and mRNA stability are coupled through the ribosomal A-site

Hanson, G.; Alhusaini, N.; Morris, N.; Sweet, T.; Coller, J.

10.1101/300467 — molecular biology — Posted on 2018-04-12

1236 Pushing the limits of de novo genome assembly for complex prokaryotic genomes harboring very long, near identical repeats

Schmid, M.; Frei, D.; Patrignani, A.; Schlapbach, R.; Frey, J. E.; Remus-Emsermann, M. N. P.; Ahrens, C. H.

10.1101/300186 — genomics — Posted on 2018-04-12

1237 Visual reconstruction from 2-photon calcium imaging suggests linear readout properties of neurons in mouse primary visual cortex

Garasto, S.; Bharath, A. A.; Schultz, S. R.

10.1101/300392 — neuroscience — Posted on 2018-04-12

1238 CHOP and IRE1α-XBP1/JNK signaling promote Newcastle Disease Virus induced apoptosis and benefit virus proliferation

Li, Y.; Liao, Y.; Niu, Q.; Gu, F.; Sun, Y.; Meng, C.; Tan, L.; Song, C.; Qiu, X.; Ding, C.

10.1101/300129 — microbiology — Posted on 2018-04-12

1239 Complete genome direct RNA sequencing of influenza A virus

Keller, M. W.; Rambo-Martin, B. L.; Wilson, M. M.; Ridenour, C. A.; Shepard, S. S.; Stark, T. J.; Neuhaus, E. B.; Dugan, V. G.; Wentworth, D. E.; Barnes, J. R.

10.1101/300384 — genomics — Posted on 2018-04-12

1240 Revisiting the social brain hypothesis: contest duration depends on loser’s brain size

van der Bijl, W.; Buechel, S. D.; Kotrschal, A.; Kolm, N.

10.1101/300335 — animal behavior and cognition — Posted on 2018-04-12

1241 Varieties of the plant Ctenante oppenheimiana: A colorful enigma of evolution.

Antunes de Almeida Filho, H.; Martinez Bruno, O.

10.1101/300376 — plant biology — Posted on 2018-04-12

1242 Evidence for multifactorial processes underlying phenotypic variation in bat visual opsins

Sadier, A.; Davies, K.; Yohe, L.; Yun, K.; Donat, P.; Hedrick, B. P.; Dumont, E.; Davalos, L.; Rossiter, S.; Sears, K. E.

10.1101/300301 — genomics — Posted on 2018-04-12

1243 Genomic resources for Goniozus legneri, Aleochara bilineata and Paykullia maculata, representing three independent origins of the parasitoid lifestyle in insects

Kraaijeveld, K.; Neleman, P.; Mariën, J.; de Meijer, E.; Ellers, J.

10.1101/300418 — genomics — Posted on 2018-04-12

1244 Insights into centriole biogenesis and evolution revealed by cryoTomography of doublet and triplet centrioles.

Greenan, G. A.; Keszthelyi, B.; Vale, R. D.; Agard, D. A.

10.1101/300525 — cell biology — Posted on 2018-04-12

1245 Precise detection of S phase onset reveals decoupled G1/S transition events

Grant, G. D.; Kedziora, K. M.; Limas, J. C.; Purvis, J. E.; Cook, J. G.

10.1101/300442 — cell biology — Posted on 2018-04-12

1246 Nonlinear dynamics of chemotherapeutic resistance

Newton, P.; Ma, Y.

10.1101/300582 — cancer biology — Posted on 2018-04-12

1247 Mass Action Kinetic Model of Apoptosis by TRAIL-Functionalized Leukocytes

Lederman, E.; King, M.

10.1101/300400 — bioengineering — Posted on 2018-04-12

1248 Molecular mechanisms controlling the multistage post-translational processing of endogenous Nrf1α/TCF11 proteins to yield distinct proteoforms within the coupled positive and negative feedback circuits

Xiang, Y.; Wang, M.; Hu, S.; Qiu, L.; Yang, F.; Zhang, Z.; Yu, S.; Pi, J.; Zhang, Y.

10.1101/300327 — biochemistry — Posted on 2018-04-12

1249 GARFIELD-NGS: Genomic vARiants FIltering by dEep Learning moDels in NGS

Ravasio, V.; Ritelli, M.; Legati, A.; Giacopuzzi, E.

10.1101/149146 — bioinformatics — Posted on 2018-04-12

1250 The Role Of Circle Of Willis Anatomy Variations In Cardio-embolic Stroke - A Patient-specific Simulation Based Study.

Mukherjee, D.; Jani, N. D.; Narvid, J.; Shadden, S. C.

10.1101/190579 — bioengineering — Posted on 2018-04-12

1251 Higher physical fitness levels are associated with less language decline in healthy ageing

Segaert, K.; Lucas, S. J. E.; Burley, C. V.; Segaert, P.; Milner, A. E.; Ryan, M.; Wheeldon, L.

10.1101/197095 — neuroscience — Posted on 2018-04-12

1252 Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling

Marin Bosch, B.; Bringard, A.; Logrieco, M. G.; Lauer, E.; Imobersteg, N. M.; Ferretti, G.; Thomas, A.; Schwartz, S.; Igloi, K.

10.1101/211227 — neuroscience — Posted on 2018-04-12

1253 Coordinated cerebellar climbing fiber activity signals learned sensorimotor predictions

Heffley, W.; Song, E. Y.; Xu, Z.; Taylor, B.; Hughes, M. A.; McKinney, A.; Joshua, M.; Hull, C.

10.1101/281055 — neuroscience — Posted on 2018-04-12

1254 Morphofunctional deficits in the cerebral cortex of NeuroD2 mutant mice are associated with autism/schizophrenia-like behaviors

Bugeon, S.; Lafi, S.; Beurrier, C.; Sahu, S.; Runge, K.; Schaller, F.; Loubat, A.; Mathieu, R.; Herault, L.; Gaillard, S.; Cahuc, M.; Pallesi-Pocachard, E.; Montheil, A.; Bosio, A.; Represa, A.; Cardoso, C.; Cremer, H.; de Chevigny, A.

10.1101/296889 — neuroscience — Posted on 2018-04-12

1255 Tracking temporal hazard in the human electroencephalogram using a forward encoding model

Herbst, S. K.; Fiedler, L.; Obleser, J.

10.1101/233551 — neuroscience — Posted on 2018-04-12

1256 Sharpening of hierarchical visual feature representations of blurred images

Abdelhack, M.; Kamitani, Y.

10.1101/230078 — neuroscience — Posted on 2018-04-12

1257 Fine-grained habitat-associated genetic connectivity in an admixed population of mussels in the small isolated Kerguelen island

Fraisse, C.; Haguenauer, A.; Gerard, K.; Weber, A. A.-T.; Bierne, N.; Chenuil, A.

10.1101/239244 — evolutionary biology — Posted on 2018-04-12

1258 Ectopic expression of Hoxb1 induces cardiac and craniofacial malformations

Zaffran, S.; Odelin, G.; Stefanovic, S.; Lescroart, F.; Etchevers, H. C.

10.1101/300368 — developmental biology — Posted on 2018-04-12

1259 DREAM-Yara: An exact read mapper for very large databaseswith short update time

Dadi, T. H.; Siragusa, E.; Piro, V.; Andrusch, A.; Seiler, E.; Renard, B.; Reinert, K.

10.1101/256354 — bioinformatics — Posted on 2018-04-12

1260 RNAs as proximity labeling media for identifying nuclear speckle positions relative to the genome

Chen, W.; Yan, Z.; Li, S.; Huang, N.; Huang, X.; Zhang, J.; Zhong, S.

10.1101/300483 — bioinformatics — Posted on 2018-04-12

1261 Genomic basis of multidrug-resistance, mating, and virulence in Candida auris and related emerging species

Munoz, J. F.; Gade, L.; Chow, N. A.; Loparev, V. N.; Juieng, P.; Farrer, R. A.; Litvintseva, A. P.; Cuomo, C. A.

10.1101/299917 — genomics — Posted on 2018-04-12

1262 A potent neutralizing epitope of limited variability in the head domain of haemagglutinin as a novel influenza vaccine target

10.1101/212845 — epidemiology — Posted on 2018-04-12

1263 Ethical Shades of Gray: Questionable Research Practices in Health Professions Education

Artino, A. R.; Driessen, E. W.; Maggio, L. A.

10.1101/256982 — scientific communication and education — Posted on 2018-04-12

1264 Onset of differentiation is posttranscriptionally controlled in adult neural stem cells

Baser, A.; Dang, Y.; Skabkin, M.; Guelcueler Balta, G.; Kalamakis, G.; Kleber, S.; Goepferich, M.; Schefzik, R.; Santos Lopez, A.; Llorens Bobadilla, E.; Schultz, C.; Fischer, B.; Martin-Villalba, A.

10.1101/289868 — neuroscience — Posted on 2018-04-12

1265 Compartmentalized lymph node drainage dictates intestinal adaptive immune responses

Esterhazy, D.; Canesso, M. C.; Muller, P. A.; Lockhart, A.; Mesin, L.; Faria, A. M.; Mucida, D.

10.1101/299628 — immunology — Posted on 2018-04-12

1266 Large-scale gene losses underlie the genome evolution of parasitic plant Cuscuta australis

Sun, G.; Xu, Y.; Liu, H.; Sun, T.; Zhang, J.; Hettenhausen, C.; Shen, G.; Qi, J.; Qin, Y.; Li, J.; Wang, L.; Chang, W.; Guo, Z.; Baldwin, I. T.; Wu, J.

10.1101/285593 — genomics — Posted on 2018-04-12

1267 TAF-ChIP: An ultra-low input approach for genome wide chromatin immunoprecipitation assay

Akhtar, J.; More, P.; Kulkarni, A.; Marini, F.; Kaiser, W.; Berger, C.

10.1101/299727 — genomics — Posted on 2018-04-12

1268 JACKS: joint analysis of CRISPR/Cas9 knock-out screens

Allen, F.; Behan, F.; Iorio, F.; Yusa, K.; Garnett, M.; Parts, L.

10.1101/285114 — genomics — Posted on 2018-04-12

1269 Recent demographic histories and genetic diversity across pinnipeds are shaped by anthropogenic interactions and mediated by ecology and life-history

Stoffel, M. A.; Humble, E.; Acevedo-Whitehouse, K.; Chilvers, B. L.; Dickerson, B.; Galimberti, F.; Gemmell, N.; Goldsworthy, S. D.; Nichols, H. J.; Krueger, O.; Negro, S.; Osborne, A.; Paijmans, A. J.; Pastor, T.; Robertson, B. C.; Sanvito, S.; Schultz, J.; Shafer, A. B. A.; Wolf, J. B. W.; Hoffman, J. I.

10.1101/293894 — evolutionary biology — Posted on 2018-04-12

1270 Allele Phasing Greatly Improves the Phylogenetic Utility of Ultraconserved Elements

Andermann, T.; Fernandes, A. M.; Olsson, U.; Topel, M.; Pfeil, B.; Oxelman, B.; Aleixo, A.; Faircloth, B. C.; Antonelli, A.

10.1101/255752 — evolutionary biology — Posted on 2018-04-12

1271 A Patient-Derived Cellular Model for Huntington Disease Reveals Phenotypes at Clinically Relevant CAG Lengths

Hung, C. L. K.; Maiuri, T.; Bowie, L. E.; Gotesman, R.; Son, S.; Falcone, M.; Giordano, J. V.; Mattis, V.; Lau, T.; Kwan, V.; Wheeler, V.; Schertzer, J.; Singh, K.; Truant, R.

10.1101/291575 — cell biology — Posted on 2018-04-12

1272 A novel xenograft model reveals invasive mesenchymal transition and ineffective angiogenic response during anti-angiogenic therapy resistance

Jahangiri, A.; Chen, W.; Chandra, A.; Nguyen, A.; Yagnik, G.; Weiss, J.; Wolf, K.; Lin, G.; Mueller, S.; Rick, J.; Sidorov, M.; Flanigan, P.; Carbonell, W. S.; Diaz, A.; Gilbert, L.; Kumar, S.; Aghi, M. K.

10.1101/272328 — cancer biology — Posted on 2018-04-12

1273 Multilayer view of pathogenic SNVs in human interactome through in-silico edgetic profiling

Cui, H.; Zhao, N.; Korkin, D.

10.1101/299891 — bioinformatics — Posted on 2018-04-12

1274 Haplotype-aware genotyping from noisy long reads

Ebler, J.; Haukness, M.; Pesout, T.; Marschall, T.; Paten, B.

10.1101/293944 — bioinformatics — Posted on 2018-04-12

1275 Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

Liesecke, F.; Daudu, D.; Duge de Bernonville, R.; Besseau, S.; Clastre, M.; Courdavault, V.; De Craene, J.-O.; Creche, J.; Giglioli-Guivarc'h, N.; Glevarec, G.; Pichon, O.; Duge de Bernonville, T.

10.1101/299909 — bioinformatics — Posted on 2018-04-12

1276 Analytical Validation of Multiplex Biomarker Assay to Stratify Colorectal Cancer Samples into Molecular Subtypes

Ragulan, C.; Eason, K.; Nyamundanda, G.; Patil, Y.; Poudel, P.; Fontana, E.; Del Rio, M.; Koo, S.-L.; Tan, W. S.; Martineau, P.; Cunningham, D.; Tan, I.; Sadanandam, A.

10.1101/174847 — cancer biology — Posted on 2018-04-12

1277 Neuronal morphology and projection analysis by multispectral tracing in densely labeled mouse brain

Roossien, D. H.; Webb, J. M.; Sadis, B. V.; Yan, Y.; Min, L. Y.; Dizaji, A. S.; Bogart, L. J.; Mazuski, C.; Huth, R. S.; Stecher, J. S.; Akula, S.; Lichtman, J. W.; Hensch, T. K.; Herzog, E. D.; Cai, D.

10.1101/230458 — neuroscience — Posted on 2018-04-12

1278 Soil microbial habitats in an extreme desert Mars-analogue environment

Warren-Rhodes, K.; Lee, K.; Archer, S.; Lacap, D.; Ng-Boyle, L.; Wettergreen, D.; Zacny, K.; Demergasso, C.; Moersch, J.; Chong, G.; Vijayarangan, S.; Thebes, C.; Wagner, M.; Tanaka, K.; Hare, T.; Tate, C.; Wang, A.; Wei, J.; Foil, G.; Cabrol, N.; Pointing, S.

10.1101/269605 — microbiology — Posted on 2018-04-12

1279 Spotlight on islands: on the origin and diversification of a new lineage of the Italian wall lizard Podarcis siculus in the western Pontine Islands

Senczuk, G.; Havenstein, K.; Milana, V.; Ripa, C.; De Simone, E.; Tiedemann, R.; Castiglia, R.

10.1101/293985 — evolutionary biology — Posted on 2018-04-12

1280 Controlling fluid flow to improve cell seeding uniformity

Reynolds, P. M.; Holzmann Rasmussen, C.; Hansson, M.; Dufva, M.; Riehle, M. O.; Gadegaard, N.

10.1101/299966 — cell biology — Posted on 2018-04-12

1281 Real-time visualization and quantification of human Cytomegalovirus replication in living cells using the ANCHOR DNA labeling technology.

Mariame, B.; Kappler-Gratias, S.; Kappler, M.; Balor, S.; Gallardo, F.; Bystricky, K.

10.1101/300111 — microbiology — Posted on 2018-04-12

1282 Predicting the Impact of cis-Regulatory Variation on Alternative Polyadenylation

Bogard, N.; Linder, J.; Rosenberg, A. B.; Seelig, G.

10.1101/300061 — genomics — Posted on 2018-04-12

1283 A transmissible RNA pathway in honey bees

Maori, E.; Garbian, Y.; Kunik, V.; Mozes-Koch, R.; Malka, O.; Kalev, H.; Sabath, N.; Sela, I.; Shafir, S.

10.1101/299800 — molecular biology — Posted on 2018-04-12

1284 Pneumococcal metabolic adaptation and colonization is regulated by the two-component regulatory system 08

Gomez-Mejia, A.; Gamez, G.; Hirschmann, S.; Kluger, V.; Rath, H.; Böhm, S.; Voss, F.; Kakar, N.; Petruschka, L.; Völker, U.; Brückner, R.; Mäder, U.; Hammerschmidt, S.

10.1101/300095 — microbiology — Posted on 2018-04-12

1285 The ERBB-STAT3 Axis Drives Tasmanian Devil Facial Tumor Disease

Kosack, L.; Wingelhofer, B.; Popa, A.; Vilagos, B.; Orlova, A.; Majek, P.; Parapatics, K.; Lercher, A.; Agerer, B.; Ringler, A.; Klughammer, J.; Smyth, M.; Khamina, K.; Baazim, H.; Rosa, D. A.; Park, J.; Gunning, P. T.; Bock, C.; Siddle, H. V.; Kubicek, S.; Murchison, E. P.; Bennett, K. L.; Moriggl, R.; Bergthaler, A.

10.1101/283309 — cancer biology — Posted on 2018-04-12

1286 egtplot: A Python Package for 3-Strategy Evolutionary Games

Mirzaev, I.; Williamson, D.; Scott, J. G.

10.1101/300004 — evolutionary biology — Posted on 2018-04-12

1287 Modulation of mitochondrial Hsp90 (TRAP1) ATPase activity by calcium and magnesium

Agard, D. A.; Elnatan, D.

10.1101/300038 — biochemistry — Posted on 2018-04-11

1288 Controlling fluid flow to improve cell seeding uniformity

Reynolds, P. M.; Holzmann Rasmussen, C.; Hansson, M.; Dufva, M.; Riehle, M. O.; Gadegaard, N.

10.1101/299966 — cell biology — Posted on 2018-04-11

1289 Multilayer view of pathogenic SNVs in human interactome through in-silico edgetic profiling

Cui, H.; Zhao, N.; Korkin, D.

10.1101/299891 — systems biology — Posted on 2018-04-11

1290 Mercury methylating microbial communities of boreal forest soils

Xu, J.; Buck, M.; Eklof, K.; Osman, O. A.; Schaefer, J. K.; Bishop, K.; Björn, E.; Skyllberg, U.; Bertilsson, S.; Bravo, A. G.

10.1101/299248 — microbiology — Posted on 2018-04-11

1291 Taking sharper pictures of malaria with CAMERAs: Combined Antibodies to Measure Exposure Recency Assays

Greenhouse, B.; Smith, D. L.; Rodriguez-Barraquer, I.; Mueller, I.; Drakeley, C.

10.1101/299446 — epidemiology — Posted on 2018-04-11

1292 Careful deployment of oilseed rape crops with Rlm6 resistance gene against L. maculans is recommended to prevent the loss of efficacy of this resistance gene in French condiment mustard.

Bousset, L.; Ermel, M.; Delourme, R.

10.1101/297937 — epidemiology — Posted on 2018-04-11

1293 Quantifying the risk of local Zika virus transmission in the continental US during the 2015-2016 ZIKV epidemic

Sun, K.; Zhang, Q.; Pastore y Piontti, A.; Chinazzi, M.; Mistry, D.; Dean, N. E.; Rojas, D. P.; Merler, S.; Poletti, P.; Rossi, L.; Halloran, M. E.; Longini, I. M.; Vespignani, A.

10.1101/298315 — epidemiology — Posted on 2018-04-11

1294 A randomised exploratory investigation of the effects of Attention vs Working Memory Training on cognitive performance and everyday functioning following stroke.

Peers, P. V.; Astle, D. E.; Duncan, J.; Murphy, F.; Hampshire, A.; Das, T.; Manly, T.

10.1101/296723 — clinical trials — Posted on 2018-04-11

1295 The chromone scaffold mediated reprogramming of the epithelial mesenchymal transition prevents fibrosis

Kim, H.-S.; Kim, J.-H.; Yoon, Y.-M.; Meang, M. K.; Lee, J. Y.; Lee, T. H.; Kim, I.-H.; Youn, B.-S.

10.1101/106591 — cell biology — Posted on 2018-04-11

1296 BED-domain containing immune receptors confer diverse resistance spectra to yellow rust

Marchal, C.; Zhang, J.; Zhang, P.; Fenwick, P.; Steuernagel, B.; Adamski, N. M.; Boyd, L.; McIntosh, R.; Wulff, B. B. H.; Berry, S.; Lagudah, E.; Uauy, C.

10.1101/299651 — plant biology — Posted on 2018-04-11

1297 Enhancement of Macrophage Function by the Antimicrobial Peptide Sublancin Protects Mice from Methicillin-Resistant Staphylococcus aureus

Wang, S.; Ye, Q.; Wang, K.; Zeng, X.; Huang, S.; Yu, H.; Ge, Q.; Qi, D.; Qiao, S.

10.1101/299305 — immunology — Posted on 2018-04-11

1298 Genetic sequences are two-dimensional

Erives, A. J.

10.1101/299867 — genetics — Posted on 2018-04-11

1299 Heterogeneous exposure and hotspots for malaria vectors at three study sites in Uganda

Kang, S. Y.; Battle, K. E.; Gibson, H. S.; Cooper, L. V.; Maxwell, K.; Kamya, M.; Lindsay, S.; Dorsey, G.; Greenhouse, B.; Rodriguez-Barraquer, I.; Reiner, R. C.; Smith, D. L.; Bisanzio, D.

10.1101/299529 — ecology — Posted on 2018-04-11

1300 Ranking genome-wide correlation measurements improves microarray and RNA-seq based global and targeted co-expression networks

Liesecke, F.; Daudu, D.; Duge de Bernonville, R.; Besseau, S.; Clastre, M.; Courdavault, V.; De Craene, J.-O.; Creche, J.; Giglioli-Guivarc'h, N.; Glevarec, G.; Pichon, O.; Duge de Bernonville, T.

10.1101/299909 — bioinformatics — Posted on 2018-04-11

1301 Multinomial-Poisson mixture models reveal unexpected higher density estimates of an Andean threatened bird

Gomez-Hoyos, D. A.; Marin-Gomez, O. H.; Caicedo-Ortiz, Y.

10.1101/298091 — zoology — Posted on 2018-04-11

1302 Parameterizing neural power spectra

Haller, M.; Donoghue, T.; Peterson, E.; Varma, P.; Sebastian, P.; Gao, R.; Noto, T.; Knight, R. T.; Shestyuk, A.; Voytek, B.

10.1101/299859 — neuroscience — Posted on 2018-04-11

1303 Somatosensory imagery induces topographically specific activation patterns instrumental to fMRI-based Brain Computer Interfacing

Kaas, A. L.; Valente, G.; Goebel, R.; Sorger, B.

10.1101/296640 — neuroscience — Posted on 2018-04-11

1304 Neuropathology and cognitive performance in centenarians

Ganz, A. B.; Beker, N.; Hulsman, M.; Sikkes, S.; Netherlands Brain Bank (NBB), ; Scheltens, P.; Smit, A. B.; Rozemuller, A. J. M.; Hoozemans, J. J. M.; Holstege, H.

10.1101/298935 — neuroscience — Posted on 2018-04-11

1305 Distinct cortical-amygdala projections drive reward value encoding and retrieval

Malvaez, M.; Shieh, C.; Murphy, M. D.; Greenfield, V. Y.; Wassum, K. M.

10.1101/299958 — neuroscience — Posted on 2018-04-11

1306 Visual salience of the stop-signal affects neural dynamics of controlled inhibition

Pani, P.; Giarrocco, F.; Giamundo, M.; Montanari, R.; Brunamonti, E.; Ferraina, S.

10.1101/299560 — neuroscience — Posted on 2018-04-11

1307 Evidence against preserved syntactic comprehension in healthy aging

Poulisse, C.; Wheeldon, L.; Segaert, K.

10.1101/299883 — neuroscience — Posted on 2018-04-11

1308 Test-retest reliability and convergent validity of (R)-PK11195 outcome measures without arterial input function

Plaven-Sigray, P.; Matheson, G. J.; Cselenyi, Z.; Jucaite, A.; Farde, L.; Cervenka, S.

10.1101/298992 — neuroscience — Posted on 2018-04-11

1309 A pool of postnatally-generated interneurons persists in an immature stage in the olfactory bulb

Benito, N.; Gaborieau, E.; Sanz Diez, A.; Kosar, S.; Foucault, L.; Raineteau, O.; De Saint Jan, D.

10.1101/299511 — neuroscience — Posted on 2018-04-11

1310 An Automated Bayesian Pipeline for Rapid Analysis of Single-Molecule Binding Data

Smith, C. S.; Jouravleva, K.; Huisman, M.; Jolly, S. M.; Zamore, P. D.; Grunwald, D.

10.1101/261917 — molecular biology — Posted on 2018-04-11

1311 A planarian nidovirus expands the limits of RNA genome size

Saberi, A.; Gulyaeva, A. A.; Brubacher, J.; Newmark, P. A.; Gorbalenya, A.

10.1101/299776 — microbiology — Posted on 2018-04-11

1312 Expression levels of glycoprotein O (gO) vary between strains of human cytomegalovirus, influencing the assembly of gH/gL complexes and virion infectivity.

Zhang, L.; Zhou, M.; Stanton, R.; Kamil, J. P.; Ryckman, B. J.

10.1101/299222 — microbiology — Posted on 2018-04-11

1313 Biofilm formation on agricultural waste pretreated with cold low-pressure nitrogen plasma and corona plasma discharges

Rivka, C.; Farber, R.; Dabush-Busheri, I.; Chaniel, G.; Rozenfeld, S.; Bormashenko, E.; Multanen, V.

10.1101/299172 — microbiology — Posted on 2018-04-11

1314 Molecular determinants of enterotoxigenic Escherichia coli heat-stable toxin secretion and delivery

Zhu, Y.; Luo, Q.; Davis, S.; Westra, C.; Vickers, T. J.; Fleckenstein, J. M.

10.1101/299313 — microbiology — Posted on 2018-04-11

1315 Combinatorial Approaches to Viral Attenuation

Paff, M. L.; Jack, B. R.; Smith, B. L.; Bull, J.; Wilke, C. O.

10.1101/299180 — microbiology — Posted on 2018-04-11

1316 Repurposing cytarabine for treating primary effusion lymphoma by targeting KSHV latent and lytic replications

Gruffaz, M.; Zhou, S.; Vasan, K.; Rushing, T.; Michael, Q. L.; Lu, C.; Jung, J. U.; Gao, S.-J.

10.1101/299339 — microbiology — Posted on 2018-04-11

1317 Oligotyping Bacterial Symbionts of Hindgut Protists Reveals Complex Population Structures and Transmission Trends in the Termite Reticulitermes flavipes

Stephens, M. E.; Gage, D. J.

10.1101/299255 — microbiology — Posted on 2018-04-11

1318 Metagenomic sequencing provides insights into the location of microbial detoxification in the gut of a small mammalian herbivore

Kohl, K. D.; Oakeson, K. F.; Orr, T. J.; Miller, A. W.; Forbey, J. S.; Phillips, C. D.; Dale, C.; Weiss, R. B.; Dearing, M. D.

10.1101/299198 — microbiology — Posted on 2018-04-11

1319 A single-domain response regulator functions as integrating hub to coordinate general stress response and development in alpha-proteobacteria

Lori, C.; Kaczmarczyk, A.; de Jong, I.; Jenal, U.

10.1101/299479 — microbiology — Posted on 2018-04-11

1320 Detection of Leishmania DNA in saliva among patients with HIV/AIDS in Trang Province, southern Thailand

Pandey, N.; Siripattanapipong, S.; Leelayoova, S.; Manomat, J.; Mungthin, M.; Bualert, L.; Naaglor, T.; Siriyasatien, P.; Phumee, A.; Piyaraj, P.

10.1101/299297 — microbiology — Posted on 2018-04-11

1321 Marginal Effects of Systemic CCR5 Blockade with Maraviroc on Oral Simian Immunodeficiency Virus Transmission to Infant Macaques

Brocca-Cofano, E.; Xu, C.; Wetzel, K.; Cottrell, M.; Policicchio, B.; Raehtz, K.; Ma, D.; Dunsmore, T.; Haret-Richter, G.; Musaitif, K.; Keele, B. F.; Kashuba, A. D.; Collman, R.; Pandrea, I.; Apetrei, C.

10.1101/299206 — immunology — Posted on 2018-04-11

1322 Immunization by replication-competent controlled herpesvirus vectors

Bloom, D. C.; Tran, R. K.; Feller, J.; Voellmy, R. W.

10.1101/299230 — immunology — Posted on 2018-04-11

1323 Compartmentalized lymph node drainage dictates intestinal adaptive immune responses

Esterhazy, D.; Canesso, M. C.; Muller, P. A.; Lockhart, A.; Mesin, L.; Faria, A. M.; Mucida, D.

10.1101/299628 — immunology — Posted on 2018-04-11

1324 Characterisation of the UK honey bee (Apis mellifera) metagenome.

Regan, T.; Barnett, M. W.; Laetsch, D. R.; Bush, S. J.; Wragg, D.; Budge, G. E.; Highet, F.; Dainat, B.; de Miranda, J. R.; The Bee Microbiome Consortium, ; Blaxter, M.; Freeman, T. C.

10.1101/293647 — genomics — Posted on 2018-04-11

1325 Genomic basis of multidrug-resistance, mating, and virulence in Candida auris and related emerging species

Munoz, J. F.; Gade, L.; Chow, N. A.; Loparev, V. N.; Juieng, P.; Farrer, R. A.; Litvintseva, A. P.; Cuomo, C. A.

10.1101/299917 — genomics — Posted on 2018-04-11

1326 Common genetic variants and health outcomes appear geographically structured in the UK Biobank sample: Old concerns returning and their implications.

Haworth, S.; Mitchell, R.; Corbin, L.; Wade, K. H.; Dudding, T.; Budu-Aggrey, A.; Carslake, D.; Hemani, G.; Paternoster, L.; Davey Smith, G.; Davies, N.; Lawson, D.; Timpson, N.

10.1101/294876 — genetics — Posted on 2018-04-11

1327 Brain scans from 21297 individuals reveal the genetic architecture of hippocampal subfield volumes

van der Meer, D.; Rokicki, J.; Kaufmann, T.; Cordova Palomera, A.; Moberget, T.; Alnaes, D.; Bettella, F.; Frei, O.; Doan, N. T.; Agartz, I.; Bertolino, A.; Bralten, J.; Brandt, C.; Buitelaar, J.; Djurovic, S.; van Donkelaar, M.; Dorum, E.; Espeseth, T.; Faraone, S.; Fernandez, G.; Fisher, S.; Franke, B.; Haatveit, B.; Hartman, C.; Hoekstra, P.; Haberg, A.; Jonsson, E.; Kolskaar, K.; Le Hellard, S.; Lund, M.; Lundervold, A.; Lundervold, A.; Melle, I.; Monereo Sanchez, J.; Norbom, L.; Nordvik, J.; Nyberg, L.; Oosterlaan, J.; Papalino, M.; Papassotiropoulos, A.; Pergola, G.; de Quervain, D.; Ric

10.1101/299578 — genetics — Posted on 2018-04-11

1328 Spatial soft sweeps: patterns of adaptation in populations with long-range dispersal

Paulose, J.; Hermisson, J.; Hallatschek, O.

10.1101/299453 — evolutionary biology — Posted on 2018-04-11

1329 Giant Viruses and their mobile genetic elements: the molecular symbiotic hypothesis

Jonathan, F.

10.1101/299784 — evolutionary biology — Posted on 2018-04-11

1330 Intra-host symbiont diversity and extended symbiont maintenance in photosymbiotic Acantharea (clade F)

Mars Brisbin, M.; Mesrop, L. Y.; Grossmann, M. M.; Mitarai, S.

10.1101/299495 — ecology — Posted on 2018-04-11

1331 Which food patches are worth exploring? Foraging desert birds do not follow environmental indicators of seed abundance at small scales: a field experiment

Milesi, F. A.; Lopez de Casenave, J.; Cueto, V. R.

10.1101/295923 — ecology — Posted on 2018-04-11

1332 Endogenous fluctuations of OCT4 and SOX2 bias pluripotent cell fate decisions

Strebinger, D.; Friman, E. T.; Deluz, C.; Govindan, S.; Alber, A. B.; Suter, D. M.

10.1101/299073 — developmental biology — Posted on 2018-04-11

1333 SORLA-driven endosomal trafficking regulates the oncogenic fitness of HER2

Pietila, M.; Sahgal, P.; Peuhu, E.; Jantti, N.; Paatero, I.; Andersen, O. M.; Padzik, A.; Blomqvist, M.; Saarinen, I.; Bostrom, P.; Taimen, P.; Ivaska, J.

10.1101/299586 — cell biology — Posted on 2018-04-11

1334 Human Papillomavirus Type 16 L1/L2 VLP Experimental Internalisation by Human Peripheral Blood Leukocytes

Cianciarullo, A. M.; Szulczewski, V.; Kavati, E. A.; Hosoda, T. M.; Leao, E.; Borelli, P.; Boccardo, E.; Mueller, M.; Karanam, B.; Becak, W.

10.1101/299214 — cancer biology — Posted on 2018-04-11

1335 Confidence Analysis of DEER Data and its Structural Interpretation with Ensemble-Biased Metadynamics

Hustedt, E. J.; Martinelli, F.; Stein, R. A.; Faraldo-Gomez, J.; Mchaourab, H.

10.1101/299941 — biophysics — Posted on 2018-04-11

1336 Positive Cardiac Inotrope, Omecamtiv Mecarbil, Activates Muscle Despite Suppressing the Myosin Working Stroke

Woody, M. S.; Greenberg, M. J.; Barua, B.; Winkelmann, D. A.; Goldman, Y. E.; Ostap, E. M.

10.1101/298141 — biophysics — Posted on 2018-04-11

1337 ampvis2: an R package to analyse and visualise 16S rRNA amplicon data

Skytte Andersen, K. S.; Kirkegaard, R. H.; Karst, S. M.; Albertsen, M.

10.1101/299537 — bioinformatics — Posted on 2018-04-11

1338 Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a synthetic gut community

D'hoe, K.; Vet, S.; Faust, K.; Moens, F.; Falony, G.; Gonze, D.; Llorens-Rico, V.; Gelens, L.; Danckaert, J.; De Vuyst, L.; Raes, J.

10.1101/299644 — bioinformatics — Posted on 2018-04-11

1339 TraceSpecks: a software for automated idealization of noisy patch-clamp and imaging data

Shah, S. I.; Demuro, A.; Mak, D.-O. D.; Parker, I.; Pearson, J. E.; Ullah, G.

10.1101/299875 — bioinformatics — Posted on 2018-04-11

1340 Two biological constants for accurate classification and evolution pattern analysis of Subgen.strobus and subgen. Pinus

Zou, H.

10.1101/297606 — bioinformatics — Posted on 2018-04-11

1341 Methods for Automatic Reference Trees and Multilevel Phylogenetic Placement

Czech, L.; Stamatakis, A.

10.1101/299792 — bioinformatics — Posted on 2018-04-11

1342 Imagery of movements immediately following performance allows learning of motor skills that interfere

Sheahan, H. R.; Ingram, J. N.; Zalalyte, G. M.; Wolpert, D. M.

10.1101/299594 — animal behavior and cognition — Posted on 2018-04-11

1343 A Con Artist: Phenylphenoxybenzamide is not a Glycosyltransferase Inhibitor

Wybenga, G. G.; Wu, W.-S.

10.1101/292912 — biochemistry — Posted on 2018-04-11

1344 A multi-scale model of the yeast chromosome-segregation system

Ng, C. T.; Deng, L.; Chen, C.; Lim, H. H.; Shi, J.; Surana, U.; Gan, L.

10.1101/299487 — cell biology — Posted on 2018-04-11

1345 Myricetin Attenuates LPS-induced Inflammation in RAW 264.7 Macrophages and Mouse Models

Hou, W.; Hu, S.; Su, Z.; Wang, Q.; Meng, G.; Guo, T.; Zhang, J.; Gao, P.

10.1101/299420 — cell biology — Posted on 2018-04-11

1346 Ras Suppresses TXNIP Expression by Restricting Ribosome Translocation

Ayer, D. E.; Ye, Z.

10.1101/299354 — cancer biology — Posted on 2018-04-11

1347 Many rice genes are differentially spliced between roots and shoots but cytokinin hormone application has minimal effect on splicing

Freese, N.; Estrada, A. D.; Blakley, I. C.; Duan, J.; Loraine, A. E.

10.1101/293217 — molecular biology — Posted on 2018-04-11

1348 Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism

Dautel, S.; Khan, N.; Brandvold, K. R.; Brislawn, C. J.; Hutchison, J.; Weitz, K. W.; Heyman, H. M.; Song, H.-S.; Ilhan, Z. E.; Hill, E. A.; Hansen, J. R.; Zheng, X.; Baker, E. S.; Cort, J. R.; Kim, Y.-M.; Isern, N. G.; DiBaise, J. K.; Krajmalnik-Brown, R.; Jansson, J. K.; Wright, A. T.; Metz, T. O.; Bernstein, H. C.

10.1101/296020 — microbiology — Posted on 2018-04-11

1349 Forfeiting the founder effect: turnover defines biofilm community succession

Brislawn, C. J.; Graham, E. B.; Dana, K.; Ihardt, P.; Fansler, S. J.; Chrisler, W. B.; Cliff, J. B.; Stegen, J. C.; Moran, J. J.; Bernstein, H. C.

10.1101/282574 — ecology — Posted on 2018-04-11

1350 TAF-ChIP: An ultra-low input approach for genome wide chromatin immunoprecipitation assay

Akhtar, J.; More, P.; Kulkarni, A.; Marini, F.; Kaiser, W.; Berger, C.

10.1101/299727 — genomics — Posted on 2018-04-11

1351 Acute effects of drugs on C. elegans movement reveal complex responses and plasticity

Spensley, M. A.; Del Borrello, S.; Pajkic, D.; Fraser, A. G.

10.1101/299719 — genetics — Posted on 2018-04-11

1352 Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts.

Garieri, M.; Stamoulis, G.; Falconnet, E.; Ribaux, P.; Borel, C.; Santoni, F. A.; Antonarakis, S. E.

10.1101/298984 — genetics — Posted on 2018-04-11

1353 Eco-evolutionary dynamics under limited dispersal: ecological inheritance, helping within- and harming between-species

Mullon, C.; Lehmann, L.

10.1101/217570 — ecology — Posted on 2018-04-11

1354 Spatial Topography of Individual-Specific Cortical Networks Predicts Human Cognition, Personality and Emotion

Kong, R.; Li, J.; Orban, C.; Sabuncu, M. R.; Liu, H.; Schaefer, A.; Sun, N.; Zuo, X.-N.; Holmes, A.; Eickhoff, S. B.; Yeo, B. T. T.

10.1101/213041 — neuroscience — Posted on 2018-04-11

1355 Using Arterial Spin Labelling to Investigate Spontaneous and Evoked Ongoing Musculoskeletal Pain

Wartolowska, K. A.; Bulte, D. P.; Chappell, M. A.; Jenkinson, M.; Okell, T. W.; Webster, M.; Carr, A. J.

10.1101/163196 — neuroscience — Posted on 2018-04-11

1356 IFITM proteins inhibit HIV-1 protein synthesis

Lee, W. Y.; Liang, C.; Sloan, R.

10.1101/201525 — microbiology — Posted on 2018-04-11

1357 Paradigm Shift in Sensorimotor Control Research and Brain Machine Interface Control: The Influence of Context on Sensorimotor representations

Zhao, Y.; Hessburg, J. P.; Asok Kumar, J. N.; Francis, J. T. T.

10.1101/239814 — neuroscience — Posted on 2018-04-11

1358 Transgenerational cues about local mate competition affect offspring sex ratios in the spider mite Tetranychus urticae

Duncan, A.; Marinosci, C.; Devaux, C.; Lefevre, S.; Magalhaes, S.; Griffin, J.; Valente, A.; Ronce, O.; Olivieri, I.

10.1101/240127 — evolutionary biology — Posted on 2018-04-11

1359 Aberrant splicing in B-cell acute lymphoblastic leukemia

Black, K. L.; Naqvi, A. S.; Hayer, K. E.; Yang, S. Y.; Gillespie, E.; Bagashev, A.; Pillai, V.; Tasian, S.; Gazzara, M. R.; Carroll, M.; Taylor, D.; Lynch, K. W.; Barash, Y.; Thomas-Tikhonenko, A.

10.1101/225136 — cancer biology — Posted on 2018-04-11

1360 Multi-Omics factor analysis - a framework for unsupervised integration of multi-omic data sets

Argelaguet, R.; Velten, B.; Arnol, D.; Dietrich, S.; Zenz, T.; Marioni, J. C.; Huber, W.; Buettner, F.; Stegle, O.

10.1101/217554 — bioinformatics — Posted on 2018-04-11

1361 The fractured landscape of RNA-seq alignment: The default in our STARs

Ballouz, S.; Dobin, A.; Gingeras, T. R.; Gillis, J.

10.1101/220681 — bioinformatics — Posted on 2018-04-11

1362 The rhesus monkey hippocampus critically contributes to scene memory retrieval, but not new learning

Froudist-Walsh, S.; Browning, P. G. F.; Croxson, P. L.; Murphy, K. L.; Shamy, J. L.; Veuthey, T. L.; Wilson, C. R. E.; Baxter, M. G.

10.1101/288407 — neuroscience — Posted on 2018-04-11

1363 Methyl-CpG binding domain 2 (Mbd2) deficiency causes cognitive, social and emotional deficits and down-regulation of ortholog Autism risk genes

Lax, E.; Do-Carmo, S.; Enuka, Y.; Sapozhnikov, D. M.; Mahmood, N.; Rabbani, S.; Wang, L.; Hancock, W. W.; Yarden, Y.; Szyf, M.

10.1101/247197 — neuroscience — Posted on 2018-04-11

1364 Sequence Alignment Through the Looking Glass

Appuswamy, R.; Fellay, J.; Chaturvedi, N.

10.1101/256859 — bioinformatics — Posted on 2018-04-11

1365 AnoniMME: Bringing Anonymity to the Matchmaker Exchange Platform for Rare Disease Gene Discovery

Oprisanu, B.; De Cristofaro, E.

10.1101/262295 — genomics — Posted on 2018-04-11

1366 Flat-field illumination for quantitative fluorescence imaging

Khaw, I.; Croop, B.; Tang, J.; Moehl, A.; Fuchs, U.; Han, K. Y.

10.1101/297242 — biophysics — Posted on 2018-04-11

1367 Science podcasts: analysis of global production and output from 2004 to 2018

MacKenzie, L. E.

10.1101/298356 — scientific communication and education — Posted on 2018-04-11

1368 Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism

10.1101/296020 — microbiology — Posted on 2018-04-11

1369 Robustness of bristle number to temperature and genetic background varies with bristle type and is regulated by miR-9a.

Matamoro-Vidal, A.; Tully, T.; Courtier-Orgogozo, V.

10.1101/295485 — genetics — Posted on 2018-04-11

1370 MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2

Shivram, H.; Le, S. V.; Iyer, V. R.

10.1101/298919 — genomics — Posted on 2018-04-11

1371 Emergent sub-population behavior uncovered with a community dynamic metabolic model of Escherichia coli diauxic growth

Succurro, A.; Segre, D.; Ebenhöh, O.

10.1101/291492 — systems biology — Posted on 2018-04-11

1372 Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA

Brandani, G. B.; Takada, S.

10.1101/297762 — biophysics — Posted on 2018-04-11

1373 Modeling Spatio-temporal Dynamics of Chromatin Marks

Fiziev, P.; Ernst, J.

10.1101/239442 — bioinformatics — Posted on 2018-04-11

1374 Evolution transforms pushed waves into pulled waves

Erm, P.; Phillips, B. L.

10.1101/266007 — ecology — Posted on 2018-04-11

1375 Sox4 drives Atoh1-independent intestinal secretory differentiation toward tuft and enteroendocrine fates

Gracz, A.; Samsa, L. A.; Fordham, M. J.; Trotier, D. C.; Zwarycz, B.; Lo, Y.-H.; Bao, K.; Starmer, J.; Shroyer, N. F.; Reinhardt, R. L.; Magness, S. T.

10.1101/183400 — cell biology — Posted on 2018-04-11

1376 Correlated selection on amino acid deletion and replacement in mammalian protein sequences

Zheng, Y.; Graur, D.; Azevedo, R. B. R.

10.1101/215277 — evolutionary biology — Posted on 2018-04-11

1377 Ecological patterns are robust to use of exact sequence variants versus operational taxonomic units

Glassman, S. I.; Martiny, J. B.

10.1101/283283 — microbiology — Posted on 2018-04-11

1378 FBXL19 recruits CDK-Mediator to CpG islands of developmental genes to prime them for activation during lineage commitment

Dimitrova, E. A.; Kondo, T.; Feldmann, A.; Nakayama, M.; Koseki, Y.; Konietzny, R.; Kessler, B. M.; Koseki, H.; Klose, R. J.

10.1101/299552 — developmental biology — Posted on 2018-04-11

1379 Estimation of the cancer risk induced by rejuvenation therapy with young blood and treatment recommendations

Meyer-Hermann, M.

10.1101/298836 — systems biology — Posted on 2018-04-11

1380 Hippocampal knockdown of Piwil1 and Piwil2 enhances contextual fear memory in mice

Leighton, L. J.; Wei, W.; Ratnu, V. S.; Li, X.; Zajaczkowski, E. L.; Spadaro, P. A.; Khandelwal, N.; Kumar, A.; Bredy, T. W.

10.1101/298570 — neuroscience — Posted on 2018-04-11

1381 The Relation Between White Matter Microstructure and Network Complexity: Implications for Processing Efficiency

McDonough, I.; Siegel, J. T.

10.1101/299065 — neuroscience — Posted on 2018-04-11

1382 Approaches to maximize sgRNA-barcode coupling in Perturb-seq screens

Adamson, B.; Norman, T. M.; Jost, M.; Weissman, J. S.

10.1101/298349 — genomics — Posted on 2018-04-11

1383 CUDA RNAfold

Langdon, W. B.; Lorenz, R.

10.1101/298885 — bioinformatics — Posted on 2018-04-11

1384 Robust Perfect Adaptation in Biomolecular Reaction Networks

Xiao, F.; Doyle, J. C.

10.1101/299057 — synthetic biology — Posted on 2018-04-11

1385 Cortical activation associated with motor preparation can be used to predict the freely chosen effector of an upcoming movement and reflects response time: An fMRI decoding study

Hirose, S.; Nambu, I.; Naito, E.

10.1101/295345 — neuroscience — Posted on 2018-04-11

1386 Levetiracetam and Rufinamide are effective at supressing spike and wave seizure activity in an in vitro model of absence epilepsy.

Todorova, V.; Ford, G.; Traub, R.; Whittington, M.; Hall, S. P.

10.1101/298711 — neuroscience — Posted on 2018-04-11

1387 Multiple brain networks mediating stimulus-pain relationships in humans

Geuter, S.; Losin, E. A. R.; Roy, M.; Atlas, L. Y.; Schmidt, L.; Krishnan, A.; Koban, L.; Wager, T. D.; Lindquist, M. A.

10.1101/298927 — neuroscience — Posted on 2018-04-11

1388 Developmentally arrested precursors of pontine neurons establish an embryonic blueprint of the Drosophila central complex

Andrade, I. V.; Riebli, N.; Nguyen, B.-C. M.; Omoto, J. J.; Fetter, R. D.; Cardona, A.; Hartenstein, V.

10.1101/291831 — neuroscience — Posted on 2018-04-11

1389 JACKS: joint analysis of CRISPR/Cas9 knock-out screens

Allen, F.; Behan, F.; Iorio, F.; Yusa, K.; Garnett, M.; Parts, L.

10.1101/285114 — genomics — Posted on 2018-04-11

1390 A single loss of photosynthesis in diatoms

Onyshchenko, A.; Ruck, E. C.; Nakov, T.; Alverson, A. J.

10.1101/298810 — evolutionary biology — Posted on 2018-04-11

1391 Reproducible genomics analysis pipelines with GNU Guix

Wurmus, R.; Uyar, B.; Osberg, B.; Franke, V.; Gosdschan, A.; Wreczycka, K.; Ronen, J.; Akalin, A.

10.1101/298653 — bioinformatics — Posted on 2018-04-11

1392 Science podcasts: analysis of global production and output from 2004 to 2018

MacKenzie, L. E. E.

10.1101/298356 — scientific communication and education — Posted on 2018-04-11

1393 Analysis of an open source, closed-loop, realtime system for hippocampal sharp-wave ripple disruption

Dutta, S.; Ackermann, E.; Kemere, C.

10.1101/298661 — neuroscience — Posted on 2018-04-11

1394 word2brain

Nunes, A.

10.1101/299024 — neuroscience — Posted on 2018-04-11

1395 First in-human PET study of 3 novel tau radiopharmaceuticals: RO6958948

10.1101/296764 — neuroscience — Posted on 2018-04-11

1396 Model testing for distinctive functional connectivity gradients with resting-state fMRI data

O'Rawe, J. F.; Ide, J. S.; Leung, H.-C.

10.1101/298752 — neuroscience — Posted on 2018-04-11

1397 Opposing pupil responses to offered and anticipated reward values

Cash-Padgett, T.; Azab, H.; Yoo, S. B. M.; Hayden, B. Y.

10.1101/298844 — neuroscience — Posted on 2018-04-11

1398 Inverse toeprinting: a new tool to decipher the translational arrest code

Seip, B.; Sacheau, G.; Dupuy, D.; Innis, A.

10.1101/298794 — molecular biology — Posted on 2018-04-11

1399 MicroRNAs reinforce repression of PRC2 transcriptional targets independently and through a feed-forward regulatory network with PRC2

Shivram, H.; Le, S. V.; Iyer, V. R.

10.1101/298919 — genomics — Posted on 2018-04-11

1400 Prioritizing putative influential genes in early life cardiovascular disease susceptibility by applying tissue-specific Mendelian randomization

Taylor, K.; Davey Smith, G.; Relton, C. L.; Gaunt, T. R.; Richardson, T. G.

10.1101/298687 — genetics — Posted on 2018-04-11

1401 Balancing selection drives maintenance of geneticvariation in Drosophila antimicrobial peptides

Chapman, J. R.; Hill, T.; Unckless, R. L.

10.1101/298893 — evolutionary biology — Posted on 2018-04-11

1402 Avoiding misinterpretation of regression lines in allometry: is sexual dimorphism in digit ratio spurious?

Forstmeier, W.

10.1101/298786 — zoology — Posted on 2018-04-11

1403 Cross-fostering in rodents causes region-specific alterations in entorhinal cortical gamma rhythms associated with NMDA receptor dysfunction

Hall, S. P.; Hawkins, K.; Laws, G.; Akitt, T.; Simon, A.; Davies, C.; Whittington, M. A.; Cunningham, M. O.

10.1101/298612 — neuroscience — Posted on 2018-04-11

1404 Word selectivity in high-level visual cortex and reading skill

Kubota, E. C.; Joo, S. J.; Huber, E.; Yeatman, J. D.

10.1101/296061 — neuroscience — Posted on 2018-04-11

1405 Agmatine accumulation by Pseudomonas aeruginosa clinical isolates confers antibiotic tolerance and dampens host inflammation.

McCurtain, J. L.; Gilbertsen, A. J.; Evert, C.; Williams, B. J.; Hunter, R. C.

10.1101/299099 — microbiology — Posted on 2018-04-11

1406 Lactobacillus acidophilus disrupts collaborative multispecies bile acid metabolism

Bernstein, H. C.; Dautel, S.; Khan, N.; Brandvold, K. R.; Brislawn, C. J.; Hutchison, J.; Weitz, K. W.; Heyman, H. M.; Song, H.-S.; Ilhan, Z. E.; Hill, E. A.; Hansen, J. R.; Zheng, X.; Baker, E. S.; Cort, J. R.; Kim, Y.-M.; Isern, N. G.; DiBaise, J. K.; Krajmalnik-Brown, R.; Jansson, J. K.; Wright, A. T.; Metz, T. O.

10.1101/296020 — microbiology — Posted on 2018-04-11

1407 Genetic differences between humans and other hominins contribute to the \"human condition\"

Kuhlwilm, M.; Boeckx, C.

10.1101/298950 — evolutionary biology — Posted on 2018-04-11

1408 A Notch-regulated proliferative stem cell zone in the developing spinal cord is an ancestral vertebrate trait

Lara-Ramirez, R.; Perez-Gonzalez, C.; Anselmi, C.; Patthey, C.; Shimeld, S. M.

10.1101/298877 — evolutionary biology — Posted on 2018-04-11

1409 Ecological genetic conflict between specialism and plasticity through genomic islands of divergence

Leimar, O.; Dall, S. R. X.; McNamara, J. M.; Kuijper, B.; Hammerstein, P.

10.1101/298554 — evolutionary biology — Posted on 2018-04-11

1410 A comprehensive, mechanistically detailed, and executable model of the Cell Division Cycle in Saccharomyces cerevisiae

Muenzner, U.; Klipp, E.; Krantz, M.

10.1101/298745 — systems biology — Posted on 2018-04-10

1411 A Cut/cohesin axis alters the chromatin landscape to facilitate neuroblast death

Arya, R.; Gyonjyan, S.; Harding, K.; Sarkissian, T.; Li, Y.; Zhou, L.; White, K.

10.1101/299164 — developmental biology — Posted on 2018-04-10

1412 Enchained growth and cluster dislocation: a possible mechanism for microbiota homeostasis

Bansept, F.; Moor-Schumann, K.; Diard, M.; Hardt, W.-D.; Wetter Slack, E.; Loverdo, C.

10.1101/298059 — biophysics — Posted on 2018-04-10

1413 Multiplex Enrichment and Detection of Rare KRAS Mutations in Liquid Biopsy Samples using Digital Droplet Pre-Amplification

Pratt, E.; Zhen, D. B.; Cowan, R. W.; Manning, S. L.; Qiao, E.; Cameron, H.; Schradle, K.; Simeone, D.; Rhim, A. D.

10.1101/298299 — bioengineering — Posted on 2018-04-10

1414 Who is this gene and what does it do? A toolkit for munging transcriptomics data in python

Fisher, C. K.; Smith, A. M.; Walsh, J. R.

10.1101/299107 — bioinformatics — Posted on 2018-04-10

1415 Comparison of Prognostic Accuracy of the quick Sepsis-Related Organ Failure Assessment between Short- & Long-term Mortality in Patients Presenting Outside of The Intensive Care Unit - A Systematic Review & Meta-analysis

TAN, T. L.; Tang, Y. J.; Ching, L. J.; Abdullah, N.; Neoh, H.-m.

10.1101/296459 — epidemiology — Posted on 2018-04-10

1416 A Single-Cell Atlas of Cell Types, States, and Other Transcriptional Patterns from Nine Regions of the Adult Mouse Brain

Saunders, A.; Macosko, E.; Wysoker, A.; Goldman, M.; Krienen, F.; Bien, E.; Baum, M.; Wang, S.; Goeva, A.; Nemesh, J.; Kamitaki, N.; Brumbaugh, S.; Kulp, D.; McCarroll, S. A.

10.1101/299081 — neuroscience — Posted on 2018-04-10

1417 Pisces: An Accurate and Versatile Variant Caller for Somatic and Germline Next-Generation Sequencing Data

Dunn, T.; Berry, G.; Emig-Agius, D.; Jiang, Y.; Lei, S.; Iyer, A.; Udar, N.; Chuang, H.-Y.; Hegarty, J.; Dickover, M.; Klotzle, B.; Robbins, J.; Bibikova, M.; Peeters, M.; Stromberg, M.

10.1101/291641 — bioinformatics — Posted on 2018-04-10

1418 Label-free visualization of type IV pili dynamics by interferometric scattering microscopy

Tala, L.; Fineberg, A.; Kukura, P.; Persat, A.

10.1101/298562 — microbiology — Posted on 2018-04-10

1419 Validation of a library of cGMP-compliant human pluripotent stem cell lines for use in liver therapy

Blackford, S. J. I.; Ng, S. S.; Segal, J. M.; King, A. J. F.; Moore, J.; Sheldon, M.; Ilic, D.; Dhawan, A.; Mitry, R.; Rashid, S. T.

10.1101/298760 — cell biology — Posted on 2018-04-10

1420 A parsimonious software sensor for estimating the individual dynamic pattern of methane emissions from cattle

Munoz-Tamayo, R.; Ramirez Agudelo, J. F.; Dewhurst, R. J.; Miller, G.; Vernon, T.; Kettle, H.

10.1101/298679 — bioengineering — Posted on 2018-04-10

1421 Neurobehavioural Correlates of Obesity are Largely Heritable

Vainik, U.; Baker, T. B.; Dadar, M.; Zeighami, Y.; Michaud, A.; Zhang, Y.; Alanis, J. C. G.; Misic, B.; Collins, D. L.; Dagher, A.

10.1101/204917 — neuroscience — Posted on 2018-04-10

1422 Protein interaction energy landscapes are shaped by functional and also non-functional partners

Schweke, H.; Mucchielli, M.-H.; Sacquin-Mora, S.; Bei, W.; Lopes, A.

10.1101/298174 — bioinformatics — Posted on 2018-04-10

1423 The Neural Circuitry Of Emotion-Induced Distortions Of Trust

Engelmann, J. B.; Meyer, F.; Ruff, C. C.; Fehr, E.

10.1101/129130 — neuroscience — Posted on 2018-04-10

1424 Cost-effectiveness of telephone-based weight loss support for patients with knee osteoarthritis: a pragmatic randomised controlled trial

O'Brien, K. M.; van Dongen, J. M.; Williams, A.; Kamper, S. J.; Wiggers, J.; Hodder, R. K.; Campbell, E.; Robson, E. K.; Haskins, R.; Rissel, C.; Williams, C. M.

10.1101/284588 — clinical trials — Posted on 2018-04-10

1425 Origins of fractional control in regulated cell death

Santos, L. C.; Vogel, R.; Chipuk, J. E.; Birtwistle, M. R.; Stolovitzky, G.; Meyer, P.

10.1101/201160 — systems biology — Posted on 2018-04-10

1426 Abstract concept learning in a simple neural network inspired by the insect brain

Cope, A. J.; Vasilaki, E.; Minors, D.; Sabo, C.; Marshall, J. A. R.; Barron, A. B.

10.1101/268375 — neuroscience — Posted on 2018-04-10

1427 A Multifactorial Model of T Cell Expansion and Durable Clinical Benefit in Response to a PD-L1 Inhibitor

Leiserson, M. D.; Syrgkanis, V.; Gilson, A.; Dudik, M.; Gillett, S.; Chayes, J.; Borgs, C.; Bajorin, D. F.; Rosenberg, J.; Funt, S.; Snyder, A.; Mackey, L.

10.1101/231316 — cancer biology — Posted on 2018-04-10

1428 Bayesian phylodynamic inference with complex models

Volz, E.; Siveroni, I.

10.1101/268052 — bioinformatics — Posted on 2018-04-10

1429 Marionette: E. coli containing 12 highly-optimized small molecule sensors

Meyer, A. J.; Segall-Shapiro, T. H.; Voigt, C. A.

10.1101/285866 — synthetic biology — Posted on 2018-04-10

1430 PEER PRESENCE AND FAMILIARITY AS KEY FACTORS TO REDUCE COCAINE INTAKE: EVIDENCE FROM TRANSLATIONAL RESEARCH

Giorla, E.; Nordmann, S.; Pelloux, Y.; Roux, P.; Rosellini, S.; Davranche, K.; Montanari, C.; Vilotitch, A.; Huguet, P.; Carrieri, P.; Baunez, C.

10.1101/286518 — neuroscience — Posted on 2018-04-10

1431 Functional equivalence of genome sequencing analysis pipelines enables harmonized variant calling across human genetics projects

Regier, A. A.; Farjoun, Y.; Larson, D.; Krasheninina, O.; Kang, H. M.; Howrigan, D. P.; Chen, B.-J.; Kher, M.; Banks, E.; Ames, D. C.; English, A. C.; Li, H.; Xing, J.; Zhang, Y.; Matise, T.; The NHLBI Trans-Omics for Precision Medicine (TOPMed) Program, ; Abecasis, G. R.; Salerno, W.; Zody, M. C.; Neale, B. M.; Hall, I. M.

10.1101/269316 — bioinformatics — Posted on 2018-04-10

1432 Prospective Motion correction improves the sensitivity of fMRI pattern decoding

Huang, P.; Carlin, J. D.; Alink, A. N.; Kriegeskorte, N. M.; Henson, R. N.; Correia, M. M.

10.1101/296442 — neuroscience — Posted on 2018-04-10

1433 Functional repair after ischemic injury through high efficiency in situ astrocyte-to-neuron conversion

Chen, Y.; Ma, N.; Pei, Z.; Wu, Z.; Do-Monte, F. H.; Huang, P.; Yellin, E.; Chen, M.; Yin, J.; Lee, G.; Minier, A.; Hu, Y.; Bai, Y.; Lee, K.; Quirk, G.; Chen, G.

10.1101/294967 — neuroscience — Posted on 2018-04-10

1434 Genetic variation/evolution and differential host responses resulting from in-patient adaptation of Mycobacterium avium

Kannan, N.; Lai, Y.-P.; Haug, M.; Lilleness, K.; Bakke, S. S.; Marstad, A.; Hov, H.; Naustdal, T.; Afset, J. E.; Ioerger, T. R.; Flo, T. H.; Steigedal, M.

10.1101/295121 — immunology — Posted on 2018-04-10

1435 mCSEA: Detecting subtle differentially methylated regions

Martorell-Marugan, J.; Gonzalez-Rumayor, V.; Carmona-Saez, P.

10.1101/293381 — bioinformatics — Posted on 2018-04-10

1436 Marine proteorhodopsins rival photosynthesis in solar energy capture

Gomez-Consarnau, L.; Levine, N. M.; Cutter, L. S.; Wang, D.; Seegers, B.; Aristegui, J.; Fuhrman, J. A.; Gasol, J. M.; Sanudo-Wilhelmy, S. A.

10.1101/231167 — ecology — Posted on 2018-04-10

1437 Early-life social environment alters juvenile behavior and neuroendocrine function in a highly social cichlid fish

Solomon-Lane, T. K.; Hofmann, H. A.

10.1101/281097 — neuroscience — Posted on 2018-04-10

1438 Aging alters envelope representations of speech-like sounds in the inferior colliculus

Parthasarathy, A.; Herrmann, B.; Bartlett, E. L.

10.1101/266650 — neuroscience — Posted on 2018-04-10

1439 Effects of autozygosity and schizophrenia polygenic risk on cognitive and brain developmental trajectories

Cordova-Palomera, A.; Kaufmann, T.; Bettella, F.; Wang, Y.; Doan, N. T.; van der Meer, D.; Alnaes, D.; Rokicki, J.; Moberget, T.; Sonderby, I. E.; Andreassen, O. A.; Westlye, L. T.

10.1101/159939 — neuroscience — Posted on 2018-04-10

1440 Identification of PTBP1 responsible for caspase dependent YRNA cleavage

Ogata, J.; Sugiura, Y.; Kanai, A.; Tanaka, M.; Matsui, H.; Ohtsuka, M.; Inaba, T.; Otsuka, M.; Kotani, A.

10.1101/298851 — molecular biology — Posted on 2018-04-10

1441 Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts.

stamoulis, g.; Garieri, M.; Falconnet, E.; Ribaux, P.; borel, c.; Santoni, F. A.; Antonarakis, S.

10.1101/298984 — genetics — Posted on 2018-04-10

1442 The geometry of partial fitness orders and an efficient method for detecting genetic interactions

Lienkaemper, C.; Lamberti, L.; Drain, J.; Beerenwinkel, N.; Gavryushkin, A.

10.1101/180976 — evolutionary biology — Posted on 2018-04-10

1443 Networks of genetic similarity reveal non-neutral processes shape strain structure in Plasmodium falciparum

He, Q.; Pilosof, S.; Tiedje, K. E.; Ruybal-Pesantez, S.; Artzy-Randrup, Y.; Baskerville, E. B.; Day, K.; Pascual, M.

10.1101/197954 — ecology — Posted on 2018-04-10

1444 MECHANOSENSATION DYNAMICALLY COORDINATES POLAR GROWTH AND CELL WALL ASSEMBLY TO PROMOTE CELL SURVIVAL

Davi, V.; Tanimoto, H.; Ershov, D.; Haupt, A.; De Belly, H.; Le Borgne, R.; Couturier, E.; Boudaoud, A.; Minc, N.

10.1101/299008 — cell biology — Posted on 2018-04-10

1445 How to overcome the ATRA resistance with the 9aaTAD activation domains in retinoic acid receptors

Piskacek, M.; Havelka, M.; Knight, A.

10.1101/298646 — cancer biology — Posted on 2018-04-10

1446 An open library of human kinase domain constructs for automated bacterial expression

Albanese, S. K.; Parton, D. L.; Isık, M.; Rodriguez-Laureano, L.; Hanson, S. M.; Behr, J. M.; Gradia, S.; Jeans, C.; Levinson, N. M.; Seeliger, M. A.; Chodera, J. D.

10.1101/038711 — biochemistry — Posted on 2018-04-10

1447 Active Learning of Cortical Connectivity from Two-Photon Imaging Data

Bertran, M.; Martinez, N.; Wang, Y.; Dunson, D.; Sapiro, G.; Ringach, D.

10.1101/268599 — neuroscience — Posted on 2018-04-10

1448 Structure-based drug design and characterization of sulfonyl-piperazine benzothiazinone inhibitors of DprE1 from Mycobacterium tuberculosis

Piton, J.; Vocat, A.; Lupien, A.; Foo, C. S.-Y.; Riabova, O.; Makarov, V.; Cole, S. T.

10.1101/298539 — pharmacology and toxicology — Posted on 2018-04-10

1449 TNF-α induces reactivation of human cytomegalovirus independently of myeloid cell differentiation following post-transcriptional establishment of latency

Hummel, M.; Forte, E.; Swaminathan, S.; Kim, J. Y.; Schroeder, M. W.; Terhune, S. S.

10.1101/298547 — microbiology — Posted on 2018-04-10

1450 Over 2000-fold increased production of the leaderless bacteriocin garvicin KS by genetic engineering and optimization of culture conditions

Diep, D. B.; Telke, A. A.; Ovchinnikov, K. V.; Vuoristo, K.; Mathiesen, G.; Thorstensen, T.

10.1101/298489 — microbiology — Posted on 2018-04-10

1451 Diverse Mechanisms of Resistance in Carbapenem-Resistant Enterobacteriaceae at a Health Care System in Silicon Valley, California

Senchyna, F.; Gaur, R.; Sandlund, J.; Truong, C.; Tremintin, G.; Küeltz, D.; Gomez, C.; Tamburini, F. B.; Andermann, T. M.; Bhatt, A. S.; Tickler, I. A.; Watz, N.; Budvytiene, I.; Shi, G.; Tenover, F. C.; Banaei, N.

10.1101/298513 — microbiology — Posted on 2018-04-10

1452 Improved CD4 T-cell profile and inflammatory levels in HIV-infected subjects on maraviroc-containing therapy is associated with better responsiveness to HBV vaccination.

Herrero-Fernandez, I.; Rosado-Sanchez, I.; Genebat, M.; Tarancon-Diez, L.; Rodriguez-Mendez, M. d. M.; Pozo-Balado, M. d. M.; Lozano, M. d. C.; Ruiz-Mateos, E.; Leal, M.; Pacheco, Y. M.

10.1101/298521 — immunology — Posted on 2018-04-10

1453 STF-62247 blocks late stages of autophagy by disrupting lysosomal physiology

Bouhamdani, N.; Comeau, D.; Cormier, K.; Turcotte, S.

10.1101/298729 — cancer biology — Posted on 2018-04-10

1454 The Translation Machinery Is Immune from miRNA Perturbations: A Cell-Based Probabilistic Approach

Mahlab-Aviv, S.; Linial, N.; Linial, M.

10.1101/298596 — systems biology — Posted on 2018-04-10

1455 A SoxB gene acts as an anterior gap gene and regulates posterior segment addition in the spider Parasteatoda tepidariorum

Paese, C. L. B.; Schoenauer, A.; Leite, D. J.; Russell, S.; McGregor, A. P.

10.1101/298448 — developmental biology — Posted on 2018-04-10

1456 EZH2 co-opts gain-of-function p53 mutants to promote cancer growth and metastasis

Zhao, Y.; Ding, L.; Wang, D.; Ye, Z.; Pan, Y.; Ma, L.; Coleman, R.; Coleman, I.; Karnes, R. J.; Zhang, J.; Nelson, P. S.; Wang, L.; Zhu, R.; Huang, H.

10.1101/298737 — cancer biology — Posted on 2018-04-10

1457 Hard decisions shape the neural coding of preferences

Voigt, K.; Murawski, C.; Speer, S.; Bode, S.

10.1101/298406 — neuroscience — Posted on 2018-04-10

1458 Epilepsy gene therapy using non-integrating lentiviral delivery of an engineered potassium channel gene

Snowball, A.; Chabrol, E.; Wykes, R. C.; Lieb, A.; Hashemi, K. S.; Kullmann, D. M.; Walker, M.; Schorge, S.

10.1101/298588 — neuroscience — Posted on 2018-04-10

1459 Low nutrient levels reduce the fitness cost of MexCD-OprJ efflux pump overexpression in ciprofloxacin-resistant Pseudomonas aeruginosa

Lin, W.; Wan, K.; Zeng, J.; Li, J.; Li, X.; Yu, X.

10.1101/298471 — microbiology — Posted on 2018-04-10

1460 Identifying the core bacterial and fungal communities within four agricultural biobeds used for the treatment of pesticide rinsates.

Bergsveinson, J.; Perry, B. J.; Sheedy, C.; Braul, L.; Reedy, S.; Gossen, B. D.; Yost, C. K.

10.1101/298331 — microbiology — Posted on 2018-04-10

1461 Cascading Effects of Shrimp Trawling: Increased Benthic Biomass and Increase in Net Primary Production

Luczkovich, J. J.; Deehr, R. A.; Hart, K. J.; Clough, L. A.; Johnson, J. C.

10.1101/298323 — ecology — Posted on 2018-04-10

1462 Peptides derived from plant virus VPg protein inhibit eIF4E oncogene

Chroboczek, J.; Wojtal, I.; Podsiadla-Bialoskorska, M.; Grzela, R.; Bujak, M.; Szolajska, E.

10.1101/298455 — cell biology — Posted on 2018-04-10

1463 Evaluation of UMAP as an alternative to t-SNE for single-cell data

Becht, E.; Dutertre, C.-A.; Kwok, I. W. H.; Ng, L. G.; Ginhoux, F.; Newell, E. W.

10.1101/298430 — bioinformatics — Posted on 2018-04-10

1464 Sex-dependent Relationship Between Wrist Deviation and Scaphoid Kinematics

Borgese, M.; Foster, B.; Boutin, R. D.; Bayne, C. O.; Szabo, R. M.; Chaudhari, A. J.

10.1101/298398 — physiology — Posted on 2018-04-10

1465 Screening of FDA-approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors

Wang, P.; Liu, Y.; Zhang, G.; Wang, S.; Guo, J.; Cao, J.; Jia, X.; Zhang, L.; Xiao, G.; Wang, W.

10.1101/298463 — microbiology — Posted on 2018-04-10

1466 Deciphering human ribonucleoprotein regulatory networks

Mukherjee, N.; Wessels, H.-H.; Lebedeva, S.; Sajek, M.; Farazi, T.; Ghanbari, M.; Garzia, A.; Munteanu, A.; Hoell, J.; Akat, K.; Tuschl, T.; Ohler, U.

10.1101/295097 — genomics — Posted on 2018-04-10

1467 Telomere length set point regulation in human pluripotent stem cells critically depends on the shelterin protein TPP1

Boyle, J. M.; Hennick, K. M.; Regalado, S. G.; Vogan, J.; Zhang, X.; Collins, K.; Hockemeyer, D.

10.1101/298778 — genetics — Posted on 2018-04-10

1468 Rapid adjustment of pecking trajectory to prism-induced visual shifts in crows.

Matsui, H.; Izawa, E.-I.

10.1101/298414 — animal behavior and cognition — Posted on 2018-04-10

1469 Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA

Brandani, G. B.; Takada, S.

10.1101/297762 — biophysics — Posted on 2018-04-10

1470 Non-Parametric Mixture Modelling and its Application to Disease Progression Modelling

Firth, N. C.; Oxtoby, N. P.; Primativo, S.; Brotherhood, E.; Young, A. L.; Yong, K. X. X.; Crutch, S. J.; Alexander, D. C.

10.1101/297978 — neuroscience — Posted on 2018-04-10

1471 Deep mutational scanning of hemagglutinin helps predict evolutionary fates of human H3N2 influenza variants

Lee, J. M.; Huddleston, J.; Doud, M. B.; Hooper, K. A.; Wu, N. C.; Bedford, T.; Bloom, J. D.

10.1101/298364 — evolutionary biology — Posted on 2018-04-10

1472 A generalized theory of somatic evolution

Rozhok, A.; DeGregori, J.

10.1101/298422 — cancer biology — Posted on 2018-04-09

1473 Long-read sequence capture elucidates the evolution of the hemoglobin gene clusters in codfishes

Hoff, S. N. K.; Baalsrud, H. T.; Tooming-Klunderud, A.; Skage, M.; Richmond, T.; Obernosterer, G.; Shirzadi, R.; Torresen, O. K.; Jakobsen, K. S.; Jentoft, S.

10.1101/297796 — genomics — Posted on 2018-04-09

1474 Protein interaction energy landscapes are shaped by functional and also non-functional partners

Schweke, H.; Mucchielli, M.-H.; Sacquin-Mora, S.; Bei, W.; Lopes, A.

10.1101/298174 — bioinformatics — Posted on 2018-04-09

1475 Systematically investigating the key features of the nuclease deactivated Cpf1 for tunable multiplex genetic regulation

Miao, C.; Zhao, H.; Qian, L.; Lou, C.

10.1101/297903 — synthetic biology — Posted on 2018-04-09

1476 Deep Learning meets Topology-preserving Active Contours: towards scalable quantitative histology of cortical cytoarchitecture.

Thierbach, K.; Bazin, P.-L.; Gavriilidis, F.; Kirilina, E.; Jaeger, C.; Morawski, M.; Geyer, S.; Weiskopf, N.; Scherf, N.

10.1101/297689 — bioinformatics — Posted on 2018-04-09

1477 Mkk4 and Mkk7 are important for retinal development and axonal injury-induced retinal ganglion cell death

Rausch, R. L.; Syc, S. B.; Fernandes, K. A.; Wilson, M. P.; Libby, R. T.

10.1101/292482 — neuroscience — Posted on 2018-04-09

1478 CD4+ T cell fate decisions are stochastic, precede cell division, depend on GITR co-stimulation, and are associated with uropodium development

Cobbold, S. P.; Adams, E.; Howie, D.; Waldmann, H.

10.1101/298026 — immunology — Posted on 2018-04-09

1479 Increased green autofluorescence is a marker for non-invasive prediction of H2O2-induced cell death and decreases in the intracellular ATP of HaCaT cells

Xu, J.; Ying, W.

10.1101/298075 — cell biology — Posted on 2018-04-09

1480 MDM4 is an essential disease driver targeted by 1q gain in Burkitt lymphoma

Huellein, J.; Slabicki, M.; Rosolowski, M.; Jethwa, A.; Habringer, S.; Tomska, K.; Kurilov, R.; Lu, J.; Scheinost, S.; Wagener, R.; Huang, Z.; Lukas, M.; Yavorska, O.; Helferich, H.; Scholtysik, R.; Bonneau, K.; Tedesco, D.; Kueppers, R.; Klapper, W.; Pott, C.; Stilgenbauer, S.; Burkhardt, B.; Loeffler, M.; Truemper, L.; Hummel, M.; Brors, B.; Zapatka, M.; Siebert, R.; Keller, U.; Huber, W.; Kreuz, M.; Zenz, T.; MMML consortium,

10.1101/289363 — cancer biology — Posted on 2018-04-09

1481 A fast and agnostic method for bacterial genome-wide association studies: bridging the gap between kmers and genetic events

Jaillard, M.; Lima, L.; Tournoud, M.; Mahe, P.; van Belkum, A.; Lacroix, V.; Jacob, L.

10.1101/297754 — bioinformatics — Posted on 2018-04-09

1482 Applying generalised allometric regressions to predict live body mass of tropical and temperate arthropods

Sohlstroem, E. H.; Marian, L.; Barnes, A. D.; Haneda, N. F.; Scheu, S.; Rall, B. C.; Brose, U.; Jochum, M.

10.1101/297697 — zoology — Posted on 2018-04-09

1483 Data-driven approaches for improving the interpretability of patch-seq data

Tripathy, S.; Toker, L.; Bomkamp, C.; Mancarci, O.; Belmadani, M.; Pavlidis, P.

10.1101/298133 — neuroscience — Posted on 2018-04-09

1484 A high-throughput technique to quantify pathogens’ virulence on the insect model Galleria mellonella

Parthuisot, N.; Rouquette, J.; Ferdy, J.-B.

10.1101/297929 — microbiology — Posted on 2018-04-09

1485 Recent demographic histories and genetic diversity across pinnipeds are shaped by anthropogenic interactions and mediated by ecology and life-history

Stoffel, M. A.; Humble, E.; Acevedo-Whitehouse, K.; Chilvers, B. L.; Dickerson, B.; Galimberti, F.; Gemmell, N.; Goldsworthy, S.; Nichols, H. J.; Krueger, O.; Negro, S.; Osborne, A.; Paijmans, A. J.; Pastor, T.; Robertson, B.; Sanvito, S.; Schultz, J.; Shafer, A.; Wolf, J.; Hoffman, J. I.

10.1101/293894 — evolutionary biology — Posted on 2018-04-09

1486 Mendelian randomization does not support serum calcium in prostate cancer risk

Yarmolinsky, J.; Berryman, K.; Langdon, R.; Bonilla, C.; the PRACTICAL consortium; Davey Smith, G.; Martin, R. M.; Lewis, S. J.

10.1101/297721 — epidemiology — Posted on 2018-04-09

1487 Addressing Confounding Factors in Algal Phosphorus Limitation Experiments

Beck, W. S.; Hall, E. K.

10.1101/298281 — ecology — Posted on 2018-04-09

1488 Homology Modeling And Docking Study Of Shewanella Like Protein Phosphatase Involved In Development Of Ookinetes In Plasmodium

Singh, S.; Yadav, R.

10.1101/297770 — bioinformatics — Posted on 2018-04-09

1489 Analyzing the symmetrical arrangement of structural repeats in proteins with CE-Symm

Bliven, S. E.; Lafita, A.; Rose, P. W.; Capitani, G.; Prlic, A.; Bourne, P.

10.1101/297960 — bioinformatics — Posted on 2018-04-09

1490 Oxidative Stress Mediates UVC-Induced Increases in Epidermal Autofluorescence of C57 Mouse Ears

Zhang, M.; Maharjan, D. T.; Li, Y.; Ying, W.

10.1101/298000 — biochemistry — Posted on 2018-04-09

1491 Creation and multi-omics characterization of a genomically hybrid strain in the nitrogen-fixing symbiotic bacterium Sinorhizobium meliloti

Checcucci, A.; diCenzo, G. C.; Ghini, V.; Bazzicalupo, M.; Beker, A.; Decorosi, F.; Dohlemann, J.; Fagorzi, C.; Finan, T. M.; Fondi, M.; Luchinat, C.; Turano, P.; Vignolini, T.; Viti, C.; Mengoni, A.

10.1101/296483 — synthetic biology — Posted on 2018-04-09

1492 Whole-brain white matter organization, intelligence, and educational attainment

Bathelt, J.; Scerif, G.; Nobre, K.; Astle, D.

10.1101/297713 — neuroscience — Posted on 2018-04-09

1493 Unique mapping of structural and functional connectivity on cognition

Zimmermann, J.; Griffiths, J.; McIntosh, A. R.

10.1101/296913 — neuroscience — Posted on 2018-04-09

1494 Dynamic Extreme Aneuploidy (DEA) in the vegetable pathogen Phytophthora capsici sheds light on instant evolution and intractability.

Lamour, K.; Shresthra, S.; Zhou, Y.; Liu, X.; Hu, J.

10.1101/297788 — genomics — Posted on 2018-04-09

1495 The histone demethylase KDM5 is essential for larval growth in Drosophila

Secombe, J.; Drelon, C.; Belalcazar, H. M.

10.1101/297804 — genetics — Posted on 2018-04-09

1496 Multidimensional Scaling and Relatedness Research

Graffelman, J.; Galvan Femenia, I.; de Cid, R.; Barcelo-i-Vidal, C.

10.1101/297879 — genetics — Posted on 2018-04-09

1497 Profound perturbation of the human metabolome by obesity

Cirulli, E. T.; Guo, L.; Leon Swisher, C.; Shah, N.; Huang, L.; Napier, L. A.; Kirkness, E. F.; Spector, T. D.; Caskey, C. T.; Thorens, B.; Venter, J. C.; Telenti, A.

10.1101/298224 — genetics — Posted on 2018-04-09

1498 Functional Quantitative Trait Loci (QTL) analysis for adaptive traits in a three-generation Scots pine pedigree

Calleja-Rodriguez, A.; Li, Z.; Hallingbäck, H. R.; Sillanpää, M. J.; Abrahamsson, S.; Wu, H. X.; Garcia-Gil, M. R.

10.1101/297986 — genetics — Posted on 2018-04-09

1499 The Drosophila mitochondrial citrate carrier regulates L-2-hydroxyglutarate accumulation by coupling the tricarboxylic acid cycle with glycolysis

Tennessen, J. M.; Li, H.; Hurlburt, A. J.

10.1101/297705 — genetics — Posted on 2018-04-09

1500 Heritability and genome-wide association study of diffusing capacity of the lung

Terzikhan, N.; Sun, F.; Verhamme, F.; Adams, H. H. H.; Loth, D.; Bracke, K.; Stricker, B.; Lahousse, L.; Josee, D.; Brusselle, G.; O'Conner, G. T.

10.1101/277343 — genetics — Posted on 2018-04-09

1501 Snapshot: clustering and visualizing epigenetic history during cell differentiation

Xiang, G.; Giardine, B.; An, L.; Sun, C.; Keller, C.; Heuston, E.; Bodine, D.; Hardison, R.; Zhang, Y.

10.1101/291880 — bioinformatics — Posted on 2018-04-09

1502 A novel emotional and cognitive approach to welfare phenotyping in rainbow trout exposed to poor water quality

Colson, V.; Mure, A.; Valotaire, C.; Le Calvez, J.-M.; Goardon, L.; Labbe, L.; Leguen, I.; Prunet, P.

10.1101/297747 — animal behavior and cognition — Posted on 2018-04-09

1503 Genetic control of transition from juvenile to mature wood with respect to microfibril angle (MFA) in Norway spruce (Picea abies) and lodgepole pine (Pinus contorta)

Hayatgheibi, H.; Forsberg, N.; Lundqvist, S.-O.; Morling, T.; Mellerowicz, E.; Karlsson, B.; Wu, H.; Garcia Gil, M. R.

10.1101/298117 — genomics — Posted on 2018-04-09

1504 Heteromeric RNP assembly at LINEs controls lineage-specific RNA processing

Attig, J.; Agostini, F.; Gooding, C.; Singh, A.; Chakrabarti, A. M.; Haberman, N.; Emmett, W.; Smith, C. W.; Luscombe, N. M.; Ule, J.

10.1101/297853 — genomics — Posted on 2018-04-09

1505 Effect of selection on bias and accuracy in genomic prediction of breeding values

Gowane, G. R.; Lee, S. H.; Clark, S.; Moghaddar, N.; Al-Mamun, H. A.; van der Werf, J. H. J.

10.1101/298042 — genomics — Posted on 2018-04-09

1506 Whence Lotka-Volterra? Conservation Laws and Integrable Systems in Ecology.

O'Dwyer, J.

10.1101/298166 — ecology — Posted on 2018-04-09

1507 Nearshore corals on the Mesoamerican Barrier Reef System on pace to cease growing as soon as year 2110

Baumann, J.; Ries, J.; Rippe, J.; Courtney, T.; Aichelman, H.; Westfield, I.; Castillo, K.

10.1101/298158 — ecology — Posted on 2018-04-09

1508 Conditional control of fluorescent protein degradation by an auxin-dependent nanobody

Daniel, K.; Icha, J.; Horenburg, C.; Muller, D.; Norden, C.; Mansfeld, J.

10.1101/298257 — cell biology — Posted on 2018-04-09

1509 Real-time observation of DNA target interrogation and product release by the RNA-guided endonuclease CRISPR Cpf1

Singh, D.; Mallon, J.; Poddar, A.; Wang, Y.; Tipanna, R.; Yang, O.; Bailey, S.; Ha, T.

10.1101/205575 — biophysics — Posted on 2018-04-09

1510 Locomotor response to acute stressors requires hypothalamic-pituitary-interrenal axis activation and glucocorticoid receptor

Lee, H. B.; Schwab, T. L.; Sigafoos, A. N.; Gauerke, J. L.; Krug, R. G.; Serres, M. R.; Jacobs, D. C.; Cotter, R. P.; Das, B.; Petersen, M. O.; Daby, C. L.; Urban, R. M.; Berry, B. C.; Clark, K. J.

10.1101/291914 — neuroscience — Posted on 2018-04-09

1511 Mapping the Peaks: Fitness Landscapes of the Fittest and the Flattest

Franklin, J.; LaBar, T.; Adami, C.

10.1101/298125 — evolutionary biology — Posted on 2018-04-09

1512 A 3D Topographical Model of Parenchymal Infiltration and Perivascular Invasion in Glioblastoma

Wolf, K. J.; Lee, S.; Kumar, S.

10.1101/298240 — bioengineering — Posted on 2018-04-09

1513 PCPE2 and SR-BI Partner to Impact Accumulation of Fat in Mice

Xu, H.; Kaul, S.; Kallinger, R.; Thomas, M. J.; Schill, R. L.; Sahoo, D.; Sorci-Thomas, M. G.

10.1101/298208 — biochemistry — Posted on 2018-04-09

1514 Nitro-Oleic Acid Induced Reactive Oxygen Species Formation and Plant Defense Signaling in Tomato Cell Suspensions

Arruebarrena Di Palma, A.; Di Fino, L. M.; Salvatore, S. R.; D`Ambrosio, J. M.; Gergoff Grozeff, G. E. E.; Garcia-Mata, C.; Schopfer, F. J.; Laxalt, A. M.

10.1101/297994 — plant biology — Posted on 2018-04-09

1515 A circadian output circuit controls sleep-wake arousal threshold in Drosophila

Guo, F.; Holla, M.; Diaz, M. M.; Rosbash, M.

10.1101/298067 — neuroscience — Posted on 2018-04-09

1516 Increased Adhesion Of CML Cells By ABL1 Tyrosine Kinase Inhibitors Induce Tunneling Nanotubes

Omsland, M.; Andresen, V.; del Pilar Ayuda Duran, M.; Gullaksen, S. E.; Hovland, R.; Enserink, J. M.; Gjertsen, B. T.

10.1101/297838 — cell biology — Posted on 2018-04-09

1517 Locomotor response to acute stressors requires hypothalamic-pituitary-interrenal axis activation and glucocorticoid receptors in zebrafish

Lee, H. B.; Schwab, T. L.; Sigafoos, A. N.; Gauerke, J. L.; Krug, R. G.; Serres, M. R.; Jacobs, D. C.; Cotter, R. P.; Das, B.; Petersen, M. O.; Daby, C. L.; Urban, R. M.; Berry, B. C.; Clark, K. J.

10.1101/291914 — neuroscience — Posted on 2018-04-09

1518 The temporal evolution of conceptual object representations revealed through models of behavior, semantics and deep neural networks

Bankson, B. B.; Hebart, M. N.; Groen, I. I. A.; Baker, C. I.

10.1101/223990 — neuroscience — Posted on 2018-04-09

1519 K-nearest neighbor smoothing for high-throughput single-cell RNA-Seq data

Wagner, F.; Yan, Y.; Yanai, I.

10.1101/217737 — bioinformatics — Posted on 2018-04-09

1520 Dynamic gain adjustments in descending corticofugal outputs from auditory cortex compensate for cochlear nerve synaptic damage

Asokan, M. M.; Williamson, R. S.; Hancock, K. E.; Polley, D. B.

10.1101/162909 — neuroscience — Posted on 2018-04-09

1521 Modularity of genes involved in local adaptation to climate despite physical linkage

Lotterhos, K.; Yeaman, S.; Degner, J.; Aitken, S.; Hodgins, K.

10.1101/202481 — evolutionary biology — Posted on 2018-04-09

1522 Enhanced Astrocyte Responses are Driven by a Genetic Risk Allele Associated with Multiple Sclerosis

Ponath, G.; Lincoln, M. R.; Dahlawi, S.; Mubarak, M.; Sumida, T.; Airas, L.; Zhang, S.; Isitan, C.; Nguyen, T. D.; Raine, C. S.; Hafler, D. A.; Pitt, D.

10.1101/206110 — neuroscience — Posted on 2018-04-09

1523 Deciphering human ribonucleoprotein regulatory networks

Mukherjee, N.; Wessels, H.-H.; Lebedeva, S.; Sajek, M.; Farazi, T.; Ghanbari, M.; Garzia, A.; Munteanu, A.; Hoell, J.; Akat, K.; Tuschl, T.; Ohler, U.

10.1101/295097 — genomics — Posted on 2018-04-09

1524 Genome-wide phenotypic analysis of growth, cell morphogenesis and cell cycle events in Escherichia coli.

Campos, M.; Govers, S. K.; Irnov, I.; Dobihal, G. S.; Cornet, F.; Jacobs-Wagner, C.

10.1101/101832 — microbiology — Posted on 2018-04-09

1525 Key role of piRNAs in telomeric chromatin maintenance and telomere nuclear positioning in Drosophila germline

Radion, E.; Morgunova, V.; Ryazansky, S.; Akulenko, N.; Lavrov, S.; Abramov, Y.; Komarov, P.; Glukhov, S.; Olovnikov, I.; Kalmykova, A.

10.1101/163030 — genomics — Posted on 2018-04-09

1526 Combining global tree cover loss data with historical national forest-cover maps to look at six decades of deforestation and forest fragmentation in Madagascar

Vieilledent, G.; Grinand, C.; Rakotomalala, F. A.; Ranaivosoa, R.; Rakotoarijaona, J.-R.; Allnutt, T. F.; Achard, F.

10.1101/147827 — ecology — Posted on 2018-04-09

1527 Interphase Human Chromosome Exhibits Out of Equilibrium Glassy Dynamics

Shi, G.; Liu, L.; Hyeon, C.; Thirumalai, D.

10.1101/193375 — biophysics — Posted on 2018-04-09

1528 Integrative analysis of transcription factor occupancy at enhancers and disease risk loci in noncoding genomic regions

Oki, S.; Ohta, T.; Shioi, G.; Hatanaka, H.; Ogasawara, O.; Okuda, Y.; Kawaji, H.; Nakaki, R.; Sese, J.; Meno, C.

10.1101/262899 — genomics — Posted on 2018-04-09

1529 Auxin is not asymmetrically distributed in initiating Arabidopsis leaves

Bhatia, N.; Heisler, M. G.

10.1101/284554 — developmental biology — Posted on 2018-04-09

1530 Robust single-cell DNA methylome profiling with snmC-seq2

Luo, C.; Rivkin, A.; Zhou, J.; Sandoval, J. P.; Kurihara, L.; Lucero, J.; Castanon, R.; Nery, J. R.; Pinto-Duarte, A.; Bui, B.; Fitzpatrick, C.; O'Connor, C.; Ruga, S.; Van Eden, M. E.; Davis, D. A.; Mash, D. C.; Behrens, M. M.; Ecker, J. R.

10.1101/294355 — genomics — Posted on 2018-04-09

1531 Riboglow: a multicolor riboswitch-based platform for live cell imaging of mRNA and small non-coding RNA in mammalian cells

Braselmann, E.; Wierzba, A. J.; Polaski, J. T.; Chrominski, M.; Holmes, Z.; Hung, S.-T.; Batan, D.; Wheeler, J.; Parker, R.; Jimenez, R.; Gryko, D.; Batey, R. T. T.; Palmer, A. E.

10.1101/199240 — biochemistry — Posted on 2018-04-09

1532 fastp: an ultra-fast all-in-one FASTQ preprocessor

Chen, S.; Zhou, Y.; Chen, Y.; Gu, J.

10.1101/274100 — bioinformatics — Posted on 2018-04-09

1533 Taxonomy annotation and guide tree errors in 16S rRNA databases

Edgar, R. C.

10.1101/288654 — microbiology — Posted on 2018-04-09

1534 C. elegans RAP-1 reinforces LET-60/Ras induction of cell fate

Rasmussen, N. R.; Dickinson, D. J.; Reiner, D. J.

10.1101/297812 — genetics — Posted on 2018-04-09

1535 Time-Periodically Driven Brownian Motion of Rigid Rod in one dimensional space

Shahzad, M. A.

10.1101/297861 — biophysics — Posted on 2018-04-09

1536 Mitochondria promote neuropeptide secretion in Caenorhabditis elegans by preventing activation of hypoxia inducible factor

Zhao, T.; Kaplan, J. M.

10.1101/298034 — neuroscience — Posted on 2018-04-09

1537 Octopaminergic neurons have multiple targets in Drosophila larval mushroom body calyx and regulate behavioral odor discrimination

McLachlan, A. D.; Wong, J. Y. H.; Wan, B. A.; O'Kane, C. J.; Montagnese, M.; Zhang, S. W.; Masuda-Nakagawa, L. M.

10.1101/295659 — neuroscience — Posted on 2018-04-09

1538 Androgen Promotes Differentiation of PLZF+ Spermatogonia pool via Indirect Regulatory Pattern

Wang, J.; Li, J.; Gu, Y.; Xia, Q.; Song, W.; Zhang, X.; Yang, Y.; Wang, W.; Li, H.; Zou, K.

10.1101/297846 — developmental biology — Posted on 2018-04-09

1539 Specific miRNA-GPCR networks regulate Sox9a/Sox9b activities to promote gonadal renewal in zebrafish

Yan, J.; Du, X.; Guo, H.; Zhang, Y.; Wu, J.; Li, M.; Hua, X.

10.1101/297820 — developmental biology — Posted on 2018-04-09

1540 Travelling waves in somitogenesis: collective cellular properties emerge from time-delayed juxtacrine oscillation coupling

Tomka, T.; Iber, D.; Boareto, M.

10.1101/297671 — developmental biology — Posted on 2018-04-09

1541 The ERBB network facilitates KRAS-driven lung tumorigenesis

Kruspig, B.; Monteverde, T.; Neidler, S.; Hock, A.; Kerr, E.; Nixon, C.; Clark, W.; Hedley, A.; Dick, C.; Vousden, K.; Martins, C.; Murphy, D.

10.1101/290700 — cancer biology — Posted on 2018-04-09

1542 Myosin filaments reversibly generate large forces in cells

Lohner, J.; Rupprecht, J.-F.; Hu, J.; Mandriota, N.; Saxena, M.; Hone, J.; Pitta de Araujo, D.; Sahin, O.; Prost, J.; Sheetz, M.

10.1101/296400 — biophysics — Posted on 2018-04-09

1543 Chromatin remodelers couple inchworm motion with twist-defect formation to slide nucleosomal DNA

Brandani, G. B.; Takada, S.

10.1101/297762 — biophysics — Posted on 2018-04-09

1544 Cancer modeling by Transgene Electroporation in Adult Zebrafish (TEAZ)

Callahan, S. J.; Tepan, S.; Zhang, Y. M.; Lindsay, H.; Burger, A.; Campbell, N. R.; Kim, I. S.; Hollmann, T. J.; Studer, L.; Mosimann, C.; White, R. M.

10.1101/297234 — cancer biology — Posted on 2018-04-09

1545 Strategies for quantitative RNA-seq analyses among closely related species

Parekh, S.; Vieth, B.; Ziegenhain, C.; Enard, W.; Hellmann, I.

10.1101/297408 — genomics — Posted on 2018-04-09

1546 The RZZ complex integrates spindle checkpoint maintenance with dynamic expansion of unattached kinetochores

Rodriguez-Rodriguez, J.-A.; McKinley, K. L.; Sikirzhytski, V.; Corona, J.; Maciejowski, J.; Khodjakov, A.; Cheeseman, I. M.; Jallepalli, P.

10.1101/297580 — cell biology — Posted on 2018-04-09

1547 Learning recurrent dynamics in spiking networks

Kim, C. M.; Chow, C. C.

10.1101/297424 — bioinformatics — Posted on 2018-04-09

1548 Rhizosphere microbes and host plant genotype influence the plant metabolome and reduce insect herbivory

Hubbard, C. J.; Li, B.; McMinn, R.; Brock, M. T.; Maignien, L.; Ewers, B.; Kliebenstein, D.; Weinig, C.

10.1101/297556 — plant biology — Posted on 2018-04-09

1549 Prospective Motion correction improves the sensitivity of fMRI pattern decoding

Huang, P.; Carlin, J. D.; Alink, A. N.; Kriegeskorte, N. M.; Henson, R. N.; Correia, M. M.

10.1101/296442 — neuroscience — Posted on 2018-04-09

1550 Analgesia linked to Nav1.7 loss of function requires mu and delta opioid receptors

Pereira, V.; Millet, Q.; Tramburu, J.; Lopez-Rodriguez, C.; Gavariaux-Ruff, C.; Wood, J. N.

10.1101/297184 — neuroscience — Posted on 2018-04-09

1551 Chromosomally Encoded mcr-5 in Colistin Non-susceptible Pseudomonas aeruginosa

Snesrud, E.; Maybank, R. A.; Kwak, Y. I.; Jones, A. R.; Hinkle, M. K.; McGann, P.

10.1101/297028 — microbiology — Posted on 2018-04-09

1552 Low-frequency variant functional architectures reveal strength of negative selection across coding and non-coding annotations

Gazal, S.; Loh, P.-R.; Finucane, H.; Ganna, A.; Schoech, A.; Sunyaev, S.; Price, A.

10.1101/297572 — genetics — Posted on 2018-04-09

1553 Congenital glaucoma with anterior segment dysgenesis in individuals with biallelic CPAMD8 variants

Siggs, O.; Souzeau, E.; Taranath, D.; Zhou, T.; Dubowsky, A.; Javadiyan, S.; Chappell, A.; Narita, A.; Elder, J.; Pater, J.; Ruddle, J.; Smith, J.; Kearns, L.; Staffieri, S.; Hewitt, A.; Mackey, D.; Burdon, K.; Craig, J.

10.1101/297077 — genetics — Posted on 2018-04-09

1554 Ecological assessment of the River Nile around Gizert El-Warrak by Phytoplankton and macroinvertebrates assemblages

Mahmoud, K. M. A.; Sayed, S. S. M.; Habib, M. R.

10.1101/297432 — ecology — Posted on 2018-04-09

1555 sFlt-1 commutes unfolded protein response into endoplasmic reticulum stress in trophoblast cells in preeclamptic pregnancies

Mochan, S.; Dhingra, M. K.; Kumar, A.; Gupta, S. K.; Saxena, S.; Arora, P.; Rani, N.; Sharma, A.; Luthra, K.; Dwivedi, S. N.; Bhatla, N.; Kumar, R.; Dhingra, R.

10.1101/297374 — developmental biology — Posted on 2018-04-09

1556 Predictive remapping of visual features beyond saccadic targets

He, T.; Fritsche, M.; de Lange, F. P.

10.1101/297481 — neuroscience — Posted on 2018-04-08

1557 Typical visual-field locations facilitate access to awareness for everyday objects

Kaiser, D.; Cichy, R. M.

10.1101/297523 — neuroscience — Posted on 2018-04-08

1558 WhiB6 is required for the secretion-dependent regulation of ESX-1 substrates in pathogenic mycobacteria.

Abdallah, A. M.; Weerdenburg, E.; Guan, Q.; Ummels, R.; Borggreve, S.; Adroub, S.; Malas, T.; Naeem, R.; Zhang, H.; Otto, T.; Bitter, W.; Pain, A.

10.1101/297440 — microbiology — Posted on 2018-04-08

1559 Recombination rate variation shapes barriers to introgression across butterfly genomes

Martin, S. H.; Davey, J.; Salazar, C.; Jiggins, C.

10.1101/297531 — evolutionary biology — Posted on 2018-04-08

1560 RGS14 restricts plasticity in hippocampal CA2 by limiting postsynaptic calcium signaling

Evans, P. R.; Parra-Bueno, P.; Smirnov, M. S.; Lustberg, D. J.; Dudek, S. M.; Hepler, J. R.; Yasuda, R.

10.1101/297499 — neuroscience — Posted on 2018-04-08

1561 Uncoupling DNA- and RNA-directed DNA methylation at Rasgrf1

Chu, E. T.; Taylor, D. H.; Hofstedt, M.; Soloway, P. D.

10.1101/297465 — molecular biology — Posted on 2018-04-08

1562 Polypyrimidine Tract Binding Protein blocks microRNA-124 biogenesis to enforce its neuronal specific expression.

Yeom, K.-H.; Mitchell, S.; Linares, A. J.; Zheng, S.; Lin, C.-H.; Wang, X.-J.; Hoffmann, A.; Black, D. L.

10.1101/297515 — molecular biology — Posted on 2018-04-08

1563 The Queen Gut Refines with Age: Longevity Phenotypes in a Social Insect Model

Anderson, K. E.; Ricigliano, V. A.; Mott, B. M.; Copeland, D. C.; Floyd, A. S.; Maes, P.

10.1101/297507 — microbiology — Posted on 2018-04-08

1564 Eco-evolutionary dynamics under limited dispersal: ecological inheritance, helping within- and harming between-species

Mullon, C.; Lehmann, L.

10.1101/217570 — ecology — Posted on 2018-04-08

1565 Typical retinotopic locations impact the time course of object coding

Kaiser, D.; Moeskops, M. M.; Cichy, R. M.

10.1101/177493 — neuroscience — Posted on 2018-04-08

1566 Sidewall cell envelope synthesis and remodeling in pole-growing mycobacteria

Garcia-Heredia, A.; Pohane, A. A.; Melzer, E. S.; Fiolek, T. J.; Rundell, S. R.; Lim, H. C.; Wagner, J.; Morita, Y. S.; Swarts, B. M.; Siegrist, M. S.

10.1101/292607 — microbiology — Posted on 2018-04-08

1567 A Defect in Influenza A Virus Particle Assembly Specific to Primary Human Macrophages

Bedi, S.; Noda, T.; Kawaoka, Y.; Ono, A.

10.1101/213447 — microbiology — Posted on 2018-04-08

1568 zUMIs: A fast and flexible pipeline to process RNA sequencing data with UMIs

Parekh, S.; Ziegenhain, C.; Vieth, B.; Enard, W.; Hellmann, I.

10.1101/153940 — bioinformatics — Posted on 2018-04-08

1569 Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi

Batty, E. M.; Chaemchuen, S.; Blacksell, S. D.; Paris, D. H.; Bowden, R.; Chan, C.; Lachumanan, R.; Day, N.; Donnelly, P.; Chen, S. L.; Salje, J.

10.1101/280958 — genomics — Posted on 2018-04-08

1570 FAVITES: simultaneous simulation of transmission networks, phylogenetic trees, and sequences

Moshiri, N.; Ragonnet-Cronin, M.; Wertheim, J. O.; Mirarab, S.

10.1101/297267 — bioinformatics — Posted on 2018-04-08

1571 The roles of vision and antennal mechanoreception in hawkmoth flight control.

Dahake, A.; Stoeckl, A.; Foster, J.; Sane, S. P.; Kelber, A.

10.1101/222448 — neuroscience — Posted on 2018-04-08

1572 Fast calcium transients in neuronal spines driven by extreme statistics

Basnayake, K.; Korkotian, E.; Holcman, D.

10.1101/290734 — cell biology — Posted on 2018-04-08

1573 Genome-wide prediction of synthetic rescue mediators of resistance to targeted and immunotherapy

Sahu, A.; Sang Lee, J.; Zhang, G.; Wang, Z.; Tian, T.; Moll, T.; Kasumova, G.; Miao, B.; Wei, Z.; Nair, N. U.; Ponomarova, O.; Friedman, A.; Amzallag, A.; Greninger, P.; Egan, R.; Damon, L.; Frederick, D.; Jerby-Arnon, L.; Wagner, A.; Cheng, K.; Robinson, W.; Park, S. G.; Gardner, K.; Hannenhalli, S.; Gutkind, S.; Boland, G.; Flaherty, K.; Benes, C.; Herlyn, M.; Bartolome, R.; Ruppin, E.

10.1101/284240 — cancer biology — Posted on 2018-04-08

1574 Study mortality with hazard rates, not probabilities

Ergon, T.; Borgan, O.; Nater, C. R.; Vindenes, Y.

10.1101/216739 — ecology — Posted on 2018-04-08

1575 Power laws and critical fragmentation in global forests

Saravia, L. A.; Doyle, S. R.; Bond-Lamberty, B.

10.1101/091751 — ecology — Posted on 2018-04-08

1576 Combining Digital Imaging and Genome Wide Association Mapping to Dissect Uncharacterized Traits in Plant/Pathogen Interactions

Fordyce, R. F.; Soltis, N. E.; Caseys, C.; Gwinner, R.; Corwin, J. A.; Atwell, S.; Copeland, d.; Feusier, J.; Subedy, A.; Eshbaugh, R.; Kliebenstein, D.

10.1101/296939 — plant biology — Posted on 2018-04-08

1577 Higher order spherical harmonics reconstruction of fetal diffusion MRI with intensity correction

Deprez, M.; Price, A. N.; Christiaens, D.; Lockwood Estrin, G.; Cordero Grande, L.; Daducci, A.; Tournier, J.-D.; Rutherford, M. A.; Counsell, S.; Bach Cuadra, M.; Hajnal, J. V.

10.1101/297341 — neuroscience — Posted on 2018-04-08

1578 Historic collections as a tool for assessing the global pollinator crisis

Bartomeus, I.; Stavert, J.; Ward, D.; Aguado, O.

10.1101/296921 — ecology — Posted on 2018-04-08

1579 Detecting Differential Variable microRNAs via Model-Based Clustering

Li, X.; Fu, Y.; Wang, X.; DeMeo, D. L.; Tantisira, K.; Weiss, S. T.; Qiu, W.

10.1101/296947 — bioinformatics — Posted on 2018-04-08

1580 A shared cis-regulatory module activates transcription in the suspensor of plant embryos

Henry, K. F.; Bui, A. Q.; Kawashima, T.; Goldberg, R. B.

10.1101/297309 — plant biology — Posted on 2018-04-08

1581 Propagation of information along the cortical hierarchy as a function of attention while reading and listening to stories

Regev, M.; Simony, E.; Lee, K.; Tan, K. M.; Chen, J.; Hasson, U.

10.1101/291526 — neuroscience — Posted on 2018-04-08

1582 Oxidative stress resistance and fitness-compensatory response in vancomycin-intermediate Staphylococcus aureus (VISA)

Tan, X.-E.; Neoh, H.-m.; Cui, L.; HIRAMATSU, K.; Jamal, R.

10.1101/297036 — microbiology — Posted on 2018-04-08

1583 Spatiotemporal discrimination in attractor networks with short-term synaptic plasticity

Shlaer, B.; Ballintyn, B.; Miller, P.

10.1101/296905 — neuroscience — Posted on 2018-04-07

1584 TOXOPLASMA ACTIVATES HOST HYPOXIA INDUCIBLE FACTOR-1 BY CYTOPLASMIC TRAPPING AND LAMP1-DEPENDENT LYSOSOMAL DEGRADATION OF PROLYL-HYDROXYLASE 2

Florimond, C.; Liu, T.; Mennendez, M.; Leppl, K.; Schofield, C. J.; Blader, I. J.

10.1101/297333 — cell biology — Posted on 2018-04-07

1585 Mechanisms of selection for the control of action in Drosophila melanogaster

Frighetto, G.; Zordan, M. A.; Castiello, U.; Megighian, A.

10.1101/296962 — animal behavior and cognition — Posted on 2018-04-07

1586 Isolation of Genomic Deoxyxylulose Phosphate Reductoisomerase (DXR) Mutations Conferring Resistance to Fosmidomycin

Pines, G.; Bassalo, M. C.; Oh, E. J.; Choudhury, A.; Garst, A. D.; Gill, R. T.

10.1101/296954 — microbiology — Posted on 2018-04-07

1587 The transcriptional and translational landscape of equine torovirus

Stewart, H.; Brown, K.; Dinan, A. M.; Irigoyen, N.; Snijder, E. J.; Firth, A.

10.1101/296996 — microbiology — Posted on 2018-04-07

1588 powerTCR: a model-based approach to comparative analysis of the clone size distribution of the T cell receptor repertoire

Koch, H.; Starenki, D.; Cooper, S. J.; Myers, R. M.; Li, Q.

10.1101/297119 — immunology — Posted on 2018-04-07

1589 Leveraging DNA methylation quantitative trait loci to characterize the relationship between methylomic variation, gene expression and complex traits.

Hannon, E.; Gorrie-Stone, T. J.; Smart, M. C.; Burrage, J.; Hughes, A.; Bao, Y.; Kumari, M.; Schalkwyk, L. C.; Mill, J.

10.1101/297176 — genetics — Posted on 2018-04-07

1590 Identifying progressive gene network perturbation from single-cell RNA-seq data

Mukherjee, S.; Carignano, A.; Seelig, G.; Lee, S.-I.

10.1101/297275 — bioinformatics — Posted on 2018-04-07

1591 Combination of tenofovir and emtricitabine with efavirenz does not moderate inhibitory effect of efavirenz on mitochondrial function and cholesterol biosynthesis in human T lymphoblastoid cell line

Li, M.; Sopeyin, A.; Paintsil, E.

10.1101/297044 — pharmacology and toxicology — Posted on 2018-04-07

1592 Effect of stimulus polarity on detection thresholds in cochlear implant users: relationships with average threshold, gap detection, and rate discrimination.

Carlyon, R. P.; Cosentino, S.; Deeks, J. M.; Parkinson, W.; Arenberg, J.

10.1101/297085 — neuroscience — Posted on 2018-04-07

1593 Autism sensory dysfunction in an evolutionarily conserved system

Vilidaite, G.; Norcia, A. M.; West, R. J. H.; Elliott, C. J. H.; Pei, F.; Wade, A. R.; Baker, D. H.

10.1101/297051 — neuroscience — Posted on 2018-04-07

1594 Reduced top-down connectivity as an underlying mechanism for psychotic experiences in healthy people

Dzafic, I.; Randeniya, R.; Garrido, M. I.

10.1101/296988 — neuroscience — Posted on 2018-04-07

1595 Born to run? Quantifying the balance of prior bias and new information in prey escape decisions

Sutton, N. M.; O'Dwyer, J.

10.1101/297218 — ecology — Posted on 2018-04-07

1596 Flat-field illumination for quantitative fluorescence imaging

Khaw, I.; Croop, B.; Tang, J.; Moehl, A.; Fuchs, U.; Han, K. Y.

10.1101/297242 — biophysics — Posted on 2018-04-07

1597 Hierarchical Cognition causes Task Related Deactivations but not just in Default Mode Regions

Farooqui, A. A.; Duncan, J.; Manly, T.

10.1101/297259 — neuroscience — Posted on 2018-04-07

1598 Core Genome Multi Locus Sequence Typing and Single Nucleotide Polymorphism Analysis in the Epidemiology of Brucella melitensis Infections

Janowicz, A.; De Massis, F.; Ancora, M.; Camma, C.; Patavino, C.; Battisti, A.; Harmsen, D.; Prior, K.; Scholz, H. C.; Zilli, K.; Sacchini, L.; Di Giannatale, E.; Garofolo, G.

10.1101/297010 — microbiology — Posted on 2018-04-07

1599 Heterogeneous Viral Strategies Promote Coexistence in Virus-Microbe Systems

Gulbudak, H.; Weitz, J.

10.1101/297127 — ecology — Posted on 2018-04-07

1600 SPORTS1.0: a tool for annotating and profiling non-coding RNAs optimized for rRNA- and tRNA- derived small RNAs

Shi, J.; Ko, E.; Sanders, K. M.; Chen, Q.; Zhou, T.

10.1101/296970 — bioinformatics — Posted on 2018-04-07

1601 FAVITES: simultaneous simulation of transmission networks, phylogenetic trees, and sequences

Moshiri, N.; Ragonnet-Cronin, M.; Wertheim, J. O.; Mirarab, S.

10.1101/297267 — bioinformatics — Posted on 2018-04-07

1602 Changes in Acceptance of Evolution and Associated Factors during a Year of Introductory Biology: The Shifting Impacts of Biology Knowledge, Politics, Religion, Demographics, and Understandings of the Nature of Science

Dunk, R. D. P.; Wiles, J. R.

10.1101/280479 — scientific communication and education — Posted on 2018-04-07

1603 Active gelation breaks time-reversal-symmetry of mitotic chromosome mechanics

Mittasch, M.; Fritsch, A. W.; Nestler, M.; Iglesias-Artola, J. M.; Subramanian, K.; Petzold, H.; Kar, M.; Voigt, A.; Kreysing, M.

10.1101/296566 — biophysics — Posted on 2018-04-07

1604 Pharmacological modulation of AMPA receptor surface diffusion restores hippocampal synaptic plasticity and memory in Huntington’s disease

Zhang, H.; Zhang, C.; Vincent, J.; Zala, D.; Benstaali, C.; Sainlos, M.; Grillo-Bosch, D.; Daburon, S.; Coussen, F.; Cho, Y.; David, D. J.; Saudou, F.; Humeau, Y.; Choquet, D.

10.1101/297069 — neuroscience — Posted on 2018-04-07

1605 The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

Begolo, D.; Vincent, I. M.; Giordani, F.; Witty, M. J.; Rowan, T. G.; Bengaly, Z.; Gillingwater, K.; Freund, Y.; Barrett, M. P.; Clayton, C. E.

10.1101/295550 — microbiology — Posted on 2018-04-07

1606 Nucleolar stress triggers the irreversible cell cycle slow down leading to cell death during replicative aging in Saccharomyces cerevisiae

Morlot, S.; Song, J.; Leger-Silvestre, I.; Matifas, A.; Gadal, O.; Charvin, G.

10.1101/297093 — cell biology — Posted on 2018-04-07

1607 Muscleblind regulates Drosophila Dscam2 cell-type-specific alternative splicing

Li, J. S. S.; Mutemi, K. N.; Millard, S. S.

10.1101/297101 — neuroscience — Posted on 2018-04-07

1608 Deletion of YAP/TAZ in mouse neocortex impaired the proliferation and differentiation ability of neural progenitor cells

Kong, S.

10.1101/296053 — neuroscience — Posted on 2018-04-07

1609 Encoding of odor fear memories in the mouse olfactory cortex

Meissner-Bernard, C.; Dembitskaya, Y.; Venance, L.; Fleischmann, A.

10.1101/297226 — neuroscience — Posted on 2018-04-07

1610 Targeted Reactivation of FMR1 Transcription in Fragile X Syndrome Embryonic Stem Cells

Haenfler, J.; Skariah, G.; Rodriguez, C. M.; Monteiro Da Rocha, A.; Parent, J.; Smith, G. D.; Todd, P. K.

10.1101/286732 — neuroscience — Posted on 2018-04-07

1611 An inter-chromosomal transcription hub activates the unfolded protein response in plasma cells

Bortnick, A.; He, Z.; Aubrey, M.; Chandra, V.; Denholtz, M.; Chen, K.; Lin, Y. C.; Murre, C.

10.1101/295915 — immunology — Posted on 2018-04-07

1612 Distinct RanBP1 nuclear export and cargo dissociation mechanisms between fungi and animals

Li, Y.; Zhou, J.; Zhang, Y.; Zhou, Q.; Shen, X.; Jia, D.; Han, J.; Sun, Q.

10.1101/294686 — biochemistry — Posted on 2018-04-07

1613 Mice follow odor trails using stereo olfactory cues and rapid sniff to sniff comparisons

Jones, P. W.; Urban, N. N.

10.1101/293746 — animal behavior and cognition — Posted on 2018-04-07

1614 Sparse recurrent excitatory connectivity in the microcircuit of the adult mouse and human cortex

Seeman, S. C.; Campagnola, L.; Davoudian, P. A.; Hoggarth, A.; Hage, T. A.; Bosma-Moody, A.; Baker, C. A.; Lee, J. H.; Mihalas, S.; Teeter, C.; Ko, A. L.; Ojemann, J. G.; Gwinn, R. P.; Silbergeld, D. L.; Cobbs, C.; Phillips, J.; Lein, E.; Murphy, G.; Koch, C.; Zeng, H.; Jarsky, T.

10.1101/292706 — neuroscience — Posted on 2018-04-07

1615 The neurobiology of BRD1 implicates sex-biased dysregulation of nuclear receptor signaling in mental disorders

Rajkumar, A. P.; Qvist, P.; Larsen, S. H.; Lazarus, R.; Pallesen, J.; Nava, N.; Winther, G.; Liebenberg, N.; Paternoster, V.; Fryland, T.; Palmfeldt, J.; Fejgin, K.; Mork, A.; Nyegaard, M.; Pakkenberg, B.; Didriksen, M.; Nyengaard, J. R.; Wegener, G.; Mors, O.; Christensen, J. H.; Borglum, A. D.

10.1101/257170 — neuroscience — Posted on 2018-04-07

1616 A Quantitative Tractography Study into the Connectivity, Segmentation and Laterality of the Human Inferior Longitudinal Fasciculus

Panesar, S.; Yeh, F.-C.; Jacquesson, T.; Hula, W.; Fernandez-Miranda, J.

10.1101/291625 — neuroscience — Posted on 2018-04-07

1617 The Evolution of Small-RNA-Mediated Silencing of an Invading Transposable Element

Kelleher, E. S.; Azevedo, R. B. R.; Zheng, Y.

10.1101/136580 — evolutionary biology — Posted on 2018-04-07

1618 Differences in Pneumococcal Serotype Replacement in Individuals with and without Underlying Medical Conditions

Weinberger, D.; Warren, J. L.; Dalby, T.; Shapiro, E. D.; Valentiner-Branth, P.; Slotved, H.-C.; Harboe, Z. B.

10.1101/296772 — epidemiology — Posted on 2018-04-07

1619 Network-based assessment of the vulnerability of Italian regions to bovine brucellosis

Darbon, A.; Valdano, E.; Poletto, C.; Giovannini, A.; Savini, L.; Candeloro, L.; Colizza, V.

10.1101/296434 — epidemiology — Posted on 2018-04-07

1620 A Novel Household Water Insecurity Scale: Procedures and Psychometric Analysis among Postpartum Women in Western Kenya

Boateng, G. O.; Collins, S. M.; Mbullo, P.; Wekesa, P.; Onono, M.; Neilands, T. B.; Young, S. L.

10.1101/294298 — epidemiology — Posted on 2018-04-07

1621 Modeling Vaccine Trials in Epidemics with Mild and Asymptomatic Infection

Kahn, R.; Hitchings, M.; Wang, R.; Bellan, S.; Lipsitch, M.

10.1101/295337 — epidemiology — Posted on 2018-04-06

1622 Economic evaluation of a healthy lifestyle intervention for chronic low back pain: a randomised controlled trial

Williams, A.; van Dongen, J. M.; Kamper, S. J.; O'Brien, K. M.; Wolfenden, L.; Yoong, S. L.; Hodder, R. K.; Lee, H.; Robson, E. K.; Haskins, R.; Rissel, C.; Wiggers, J.; Williams, C. M.

10.1101/296285 — clinical trials — Posted on 2018-04-06

1623 Learning and Forgetting Using Reinforced Bayesian Change Detection

Moens, V.; Zenon, A.

10.1101/294959 — neuroscience — Posted on 2018-04-06

1624 Biology and taxonomy of crAss-like bacteriophages, the most abundant virus in the human gut

Guerin, E.; Shkoporov, A.; Stockdale, S.; Clooney, A. G.; Ryan, F. J.; Draper, L. A.; Gonzalez-Tortuero, E.; Ross, R. P.; Hill, C.

10.1101/295642 — microbiology — Posted on 2018-04-06

1625 Long-read whole genome sequencing and comparative analysis of six strains of the human pathogen Orientia tsutsugamushi

Batty, E. M.; Chaemchuen, S.; Blacksell, S. D.; Paris, D. H.; Bowden, R.; Chan, C.; Lachumanan, R.; Day, N.; Donnelly, P.; Chen, S. L.; Salje, J.

10.1101/280958 — genomics — Posted on 2018-04-06

1626 Improving Accuracy of Nuclei Segmentation by Reducing Histological Image Variability

Roohani, Y.; Kiss, E.

10.1101/296806 — pathology — Posted on 2018-04-06

1627 Differential DNA modification of an enhancer at the IGF2 locus affects dopamine synthesis in patients with major psychosis

Pai, S.; Li, P.; Killinger, B.; Marshall, L.; Jia, P.; Liao, J.; Petronis, A.; Szabo, P.; Labrie, V.

10.1101/296756 — neuroscience — Posted on 2018-04-06

1628 Effect Size and Power in fMRI Group Analysis

Geuter, S.; Qi, G.; Welsh, R. C.; Wager, T. D.; Lindquist, M. A.

10.1101/295048 — neuroscience — Posted on 2018-04-06

1629 Using the residual bootstrap to quantify uncertainty in mean apparent propagator MRI

Gu, X.; Eklund, A.; Ozarslan, E.; Knutsson, H.

10.1101/295667 — neuroscience — Posted on 2018-04-06

1630 Flexible coding of memory and space in the primate hippocampus during virtual navigation

Gulli, R. A.; Duong, L.; Corrigan, B. W.; Doucet, G.; Williams, S.; Fusi, S.; Martinez-Trujillo, J. C.

10.1101/295774 — neuroscience — Posted on 2018-04-06

1631 Working memory availability affects neural indices of distractor processing during visual search

Henare, D. T.; Buckley, J.; Corballis, P. M.

10.1101/295378 — neuroscience — Posted on 2018-04-06

1632 Transient μm scale protein accumulation at the center of the T cell antigen presenting cell interface drives efficient IL-2 secretion

Clark, D. J.; McMillan, L. E.; Massoue, C.; Mykhaylechko, L.; Ruan, X.; Singleton, K. L.; Du, M.; Hedges, A. J.; Schwartzberg, P. L.; Murphy, R. F.; Wülfing, C.

10.1101/296616 — immunology — Posted on 2018-04-06

1633 VenomKB v2.0: A knowledge repository for computational toxinology

Romano, J.; Nwankwo, V.; Tatonetti, N.

10.1101/295204 — bioinformatics — Posted on 2018-04-06

1634 Reference-point centering and range-adaptation enhance human reinforcement learning at the cost of irrational preferences

Bavard, S.; Lebreton, M.; Khamassi, M.; Coricelli, G.; Palminteri, S.

10.1101/295022 — animal behavior and cognition — Posted on 2018-04-06

1635 Single-Cell Transcriptomic Analysis of Human Lung Reveals Complex Multicellular Changes During Pulmonary Fibrosis

Reyfman, P. A.; Walter, J. M.; Joshi, N.; Anekalla, K. R.; McQuattie-Pimentel, A. C.; Chiu, S.; Fernandez, R.; Akbarpour, M.; Chen, C.-I.; Ren, Z.; Verma, R.; Abdala-Valencia, H.; Nam, K.; Chi, M.; Han, S.; Gonzalez-Gonzalez, F. J.; Soberanes, S.; Watanabe, S.; Williams, K. J. N.; Flozak, A. S.; Nicholson, T. T.; Morgan, V. K.; Hrusch, C. L.; Guzy, R. D.; Bonham, C. A.; Sperling, A. I.; Bag, R.; Hamanaka, R. B.; Mutlu, G. M.; Yeldandi, A. V.; Marshall, S. A.; Shilatifard, A.; Amaral, L. A. N.; Perlman, H.; Sznajder, J. I.; Winter, D. R.; Hinchcliff, M.; Argento, A. C.; Gillespie, C. T.; Dematt

10.1101/296608 — systems biology — Posted on 2018-04-06

1636 Observing fear enables plasticity of the dmPFC-BLA pathway during subsequent learning of inhibitory avoidance

Ito, W.; Morozov, A.

10.1101/296681 — neuroscience — Posted on 2018-04-06

1637 Response of the multiple-demand network during simple stimulus discriminations

Wen, T.; Mitchell, D. J.; Duncan, J.

10.1101/296509 — neuroscience — Posted on 2018-04-06

1638 Development of inhibitory synaptic delay drives maturation of thalamocortical network dynamics

Romagnoni, A.; Colonnese, M.; Touboul, J.; Gutkin, B.

10.1101/296673 — neuroscience — Posted on 2018-04-06

1639 A stimulus artefact undermines the evidence for independent ON and OFF channels in stereopsis

Read, J. C. A.; Cumming, B. G.

10.1101/295618 — neuroscience — Posted on 2018-04-06

1640 Transcranial direct current stimulation alters functional network structure in humans

Ruttorf, M.; Kristensen, S.; Schad, L. R.; Almeida, J.

10.1101/296657 — neuroscience — Posted on 2018-04-06

1641 Inferring health conditions from fMRI-graph data

Porta Mana, P.; Bachmann, C.; Morrison, A.

10.1101/295113 — neuroscience — Posted on 2018-04-06

1642 Connectivity Patterns in Cognitive Control Networks Predict Naturalistic Multitasking Ability

Wen, T.; Liu, D.-C.; Hsieh, S.

10.1101/296475 — neuroscience — Posted on 2018-04-06

1643 Serotonergic regulation of corticoamygdalar neurons in the mouse prelimbic cortex

Avesar, D.; Stephens, E.; Gulledge, A. T.

10.1101/293688 — neuroscience — Posted on 2018-04-06

1644 Isolation and sequencing of AGO-bound RNAs reveals characteristics of mammalian stem-loop processing in vivo

Silverman, I. M.; Gosai, S. J.; Vrettos, N.; Foley, S. W.; Berkowitz, N. D.; Mourelatos, Z.; Gregory, B. D.

10.1101/294488 — molecular biology — Posted on 2018-04-06

1645 Shifts in the gut microbiota structure caused by Helicobacter pylori eradication therapy

10.1101/296426 — microbiology — Posted on 2018-04-06

1646 Maternal tamoxifen treatment expands the macrophage population of early mouse embryos.

Rojo, R.; Sauter, K. A.; Lefevre, L.; Hume, D. A.; Pridans, C.

10.1101/296749 — immunology — Posted on 2018-04-06

1647 Epigenetic Age-Predictor for Mice based on Three CpG Sites

Han, Y.; Eipel, M.; Sakk, V.; Dethmers-Ausema, B.; de Haan, G.; Geiger, H.; Wagner, W.

10.1101/296525 — genomics — Posted on 2018-04-06

1648 Viral Fitness Across a Continuum from Lysis to Latency

Weitz, J. S.; Li, G.; Gulbudak, H.; Cortez, M. H.; Whitaker, R. J.

10.1101/296897 — ecology — Posted on 2018-04-06

1649 Using eOceans dive-logs for science and conservation: a case of sharks in Thailand

Ward-Paige, C. A.; Westell, A.; Sing, B.

10.1101/296160 — ecology — Posted on 2018-04-06

1650 Axin proteolysis by Iduna is required for the regulation of stem cell proliferation and intestinal homeostasis in Drosophila

Gultekin, Y.; Steller, H.

10.1101/296830 — developmental biology — Posted on 2018-04-06

1651 Nucleosome conformational variability in solution and in interphase nuclei evidenced by cryo-electron miocroscopy of vitreous sections

Eltsov, M.; Grewe, D.; Lemercier, N.; Frangakis, A.; Livolant, F.; Leforestier, A.

10.1101/295691 — biophysics — Posted on 2018-04-06

1652 Comprehensive quantification of the modified proteome reveals oxidative heart damage in mitochondrial heteroplasmy

Bagwan, N.; Bonzon-Kulichenko, E.; Calvo, E.; Lechuga-Vieco, A. V.; Michalakopoulos, S.; Trevisan-Herraz, M.; Ezkurdia, I.; Rodriguez, J. M.; Magni, R.; Latorre-Pellicer, A.; Enriquez, J. A.; Vazquez, J.

10.1101/296392 — bioinformatics — Posted on 2018-04-06

1653 mCSEA: Detecting subtle differentially methylated regions

Martorell-Marugan, J.; Gonzalez-Rumayor, V.; Carmona-Saez, P.

10.1101/293381 — bioinformatics — Posted on 2018-04-06

1654 Social Motility: Interaction between two sessile soil bacteria leads to emergence of surface motility

McCully, L. M.; Bitzer, A. S.; Seaton, S. C.; Smith, L. M.; Silby, M. W.

10.1101/296814 — microbiology — Posted on 2018-04-06

1655 Organizing neuronal ER-PM junctions is a conserved nonconducting function of Kv2 plasma membrane ion channels

Kirmiz, M.; Palacio, S.; Thapa, P.; King, A. N.; Sack, J. T.; Trimmer, J.

10.1101/296731 — cell biology — Posted on 2018-04-06

1656 Motor resonance in primary motor cortex reflects the integration of kinematic and contextual information in accordance to a Bayesian predictive coding framework

Cretu, A.; Germann, M.; Ruddy, K.; Wenderoth, N.

10.1101/293977 — neuroscience — Posted on 2018-04-06

1657 Humans strategically shift decision bias by flexibly adjusting sensory evidence accumulation in visual cortex

Kloosterman, N. A.; de Gee, J. W.; Werkle-Bergner, M.; Lindenberger, U.; Garrett, D. D.; Fahrenfort, J. J.

10.1101/229989 — neuroscience — Posted on 2018-04-06

1658 An inter-chromosomal transcription hub activates the unfolded protein response in plasma cells

Bortnick, A.; He, Z.; Aubrey, M.; Chandra, V.; Denholtz, M.; Chen, K.; Lin, Y. C.; Murre, C.

10.1101/295915 — immunology — Posted on 2018-04-06

1659 Integrating Predicted Transcriptome From Multiple Tissues Improves Association Detection

Barbeira, A. N.; Pividori, M. D.; Zheng, J.; Wheeler, H. E.; Nicolae, D. L.; Im, H. K.

10.1101/292649 — genomics — Posted on 2018-04-06

1660 Craniofacial traits determined by neural crest cells-restricted expression of Dlx5/6: probing the origin of matching functional jaws

10.1101/296665 — developmental biology — Posted on 2018-04-06

1661 Translocation of structured biomolecule through a vibrating nanopore

Shahzad, M. A.

10.1101/296780 — biophysics — Posted on 2018-04-06

1662 Prognostic models for Ebola virus disease derived from data collected at five treatment units in Sierra Leone and Liberia: performance, external validation, and risk visualization

Colubri, A.; Levine, A. C.; Siakor, M.; Wolfman, V.; Hartley, M.-A.; Sesay, T.; Felix, A.; Sabeti, P. C.

10.1101/294587 — bioinformatics — Posted on 2018-04-06

1663 Accurate informatic modeling of tooth enamel pellicle interactions by training substitution matrices with Mat4Pep

Horst, J. A.; Seto, J.; Oren, E. E.; Horst, O. V.; Hung, L.-H. H.; Samudrala, R.

10.1101/295857 — bioinformatics — Posted on 2018-04-06

1664 Cluster Failure Revisited: Impact of First Level Design and Data Quality on Cluster False Positive Rates

Eklund, A.; Knutsson, H.; Nichols, T. E.

10.1101/296798 — neuroscience — Posted on 2018-04-06

1665 Role of the default mode network in cognitive transitions

Smith, V.; Mitchell, D. J.; Duncan, J.

10.1101/295683 — neuroscience — Posted on 2018-04-06

1666 Reproducible evaluation of classification methods in Alzheimer’s disease: framework and application to MRI and PET data

Samper-Gonzalez, J.; Burgos, N.; Bottani, S.; Fontanella, S.; Lu, P.; Marcoux, A.; Routier, A.; Guillon, J.; Bacci, M.; Wen, J.; Bertrand, A.; Bertin, H.; Habert, M.-O.; Durrleman, S.; Evgeniou, T.; Colliot, O.; the Alzheimer's Disease Neuroimaging Initiative, ; the Australian Imaging Biomarkers and Lifestyle flagship study of ageing,

10.1101/274324 — neuroscience — Posted on 2018-04-06

1667 Hybridization, sex specific genomic architecture and local adaptation

Runemark, A.; Eroukhmanoff, F.; Bolanos, A. N.; Hermansen, J. S.; Meier, J.

10.1101/296632 — evolutionary biology — Posted on 2018-04-06

1668 BayesENproteomics: Bayesian elastic nets for quantification of proteoforms in complex samples

Mallikarjun, V.; Richardson, S. M.; Swift, J.

10.1101/295527 — bioinformatics — Posted on 2018-04-06

1669 Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with Adverse Drug Reactions

Ramsbottom, K. A.; Carr, D.; Jones, A. R.; Rigden, D. J.

10.1101/296574 — bioinformatics — Posted on 2018-04-06

1670 New tools for carbohydrate sulphation analysis: Heparan Sulphate 2-O-sulphotranserase (HS2ST) is a target for small molecule protein kinase inhibitors

Byrne, D. P.; Li, Y.; Ramakrishnan, K.; Barsukov, I.; Yates, E.; Eyers, C.; Papy-Garcia, D.; Chantepie, S.; Pagadala, V.; Liu, J.; Wells, C.; Drewry, D.; Zuercher, W.; Berry, N.; Fernig, D.; Eyers, P. A.

10.1101/296533 — biochemistry — Posted on 2018-04-06

1671 Terrestriality and bacterial transfer: A comparative study of gut microbiomes in sympatric Malagasy mammals

Perofsky, A. C.; Lewis, R. J.; Meyers, L. A.

10.1101/293282 — microbiology — Posted on 2018-04-06

1672 Quantitative proteomics identification of seminal fluid proteins in male Drosophila melanogaster

Sepil, I.; Hopkins, B. R.; Dean, R.; Thezenas, M.-L.; Charles, P. D.; Konietzny, R.; Fischer, R.; Kessler, B. M.; Wigby, S.

10.1101/296491 — genomics — Posted on 2018-04-06

1673 Variation in physiological function across source populations of a New Zealand freshwater snail

Greimann, E. S.; Fahrner, S.; Woodell, J. D.; Hennessey, S. K.; Kline, M. R.; Moreno, J. A.; Peters, M. R.; Cruise, J. L.; Neiman, M.; Sharbrough, J.

10.1101/230979 — evolutionary biology — Posted on 2018-04-06

1674 Novel functions for integrin-associated proteins revealed by myofibril attachment in Drosophila

Green, H. J.; Griffiths, A.; Brown, N.

10.1101/296699 — developmental biology — Posted on 2018-04-06

1675 Tissue flow induces cell shape changes during organogenesis

Erdemci-Tandogan, G.; Clark, M. J.; Amack, J. D.; Manning, M. L.

10.1101/295840 — biophysics — Posted on 2018-04-06

1676 New tools for evaluating protein tyrosine sulphation: Tyrosyl Protein Sulphotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors

Eyers, P.; Byrne, D.; Ngamlert, P.; Li, Y.; Ramakrishnan, K.; Eyers, C.; Wells, C.; Drewry, D.; Zuercher, W.; Berry, N.; Fernig, D.

10.1101/296707 — biochemistry — Posted on 2018-04-06

1677 The structural basis for cancer drug interactions with the catalytic and allosteric sites of SAMHD1

Knecht, K. M.; Buzovetsky, O.; Schneider, C.; Thomas, D.; Srikanth, V.; Tofoleanu, F.; Reiss, K.; Ferreiros, N.; Geisslinger, G.; Batista, V. S.; Ji, X.; Cinatl, J.; Keppler, O. T.; Xiong, Y.

10.1101/296624 — biochemistry — Posted on 2018-04-06

1678 Deep Learning Global Glomerulosclerosis in Transplant Kidney Frozen Sections

Marsh, J. N.; Matlock, M. K.; Kudose, S.; Liu, T.-C.; Stappenbeck, T. S.; Gaut, J. P.; Swamidass, S. J.

10.1101/292789 — bioinformatics — Posted on 2018-04-06

1679 Spontaneous mutations conferring antibiotic resistance to antitubercular drugs at a range of concentrations in Mycobacterium smegmatis

Nyinoh, I. W.; McFadden, J.

10.1101/296137 — microbiology — Posted on 2018-04-06

1680 Adenylosuccinate Lyase activity in the Purine recycling pathway is essential for developmental timing, germline maintenance and muscle integrity in C. elegans.

Marsac, R.; Pinson, B.; Saint-Marc, C.; Olmedo, M.; Artal-Sanz, M.; Daignan-Fornier, B.; Gomes, J.-E.

10.1101/277640 — genetics — Posted on 2018-04-06

1681 Quantifying cell densities and biovolumes of phytoplankton communities and functional groups using scanning flow cytometry, machine learning and unsupervised clustering

Thomas, M. K.; Fontana, S.; Reyes, M.; Pomati, F.

10.1101/274357 — ecology — Posted on 2018-04-06

1682 Identification of Miro as a mitochondrial receptor for myosin XIX

Bähler, M.; Oeding, S. J.; Majstrowicz, K.; Hu, X.-P.; Schwarz, V.; Freitag, A.; Honnert, U.; Nikolaus, P.

10.1101/296376 — cell biology — Posted on 2018-04-06

1683 Personal genomics: new concepts for future community data banks

Dodin, G.

10.1101/230516 — bioinformatics — Posted on 2018-04-06

1684 Acute fluoxetine differently affects aggressive display in zebrafish phenotypes

Barbosa, H. P.; Lima, M. G.; Maximino, C.

10.1101/217810 — neuroscience — Posted on 2018-04-06

1685 Integrative visual omics of the white-rot fungus Polyporus brumalis exposes the biotechnological potential of its oxidative enzymes for delignifying raw plant biomass.

Miyauchi, S.; Rancon, A.; Drula, E.; Chaduli, D.; Favel, A.; Grisel, S.; Henrissat, B.; Herpoël-Gimbert, I.; Ruiz-Duenas, F. J.; Chevret, D.; Hainaut, M.; Lin, J.; Wang, M.; Pangilinan, J.; Lipzen, A.; Lesage-Meessen, L.; Navarro, D.; Riley, R.; Grigoriev, I.; Zhou, S.; Raouche, S.; Rosso, M.-N.

10.1101/296152 — bioengineering — Posted on 2018-04-06

1686 Ref-1/APE1 inhibition with novel small molecules blocks ocular neovascularization

Sheik Pran Babu, S. P.; Sishtla, K.; Sulaiman, R. S.; Park, B.; Fishel, M. L.; Wikel, J. H.; Kelley, M. R.; Corson, T. W.

10.1101/296590 — pharmacology and toxicology — Posted on 2018-04-06

1687 A cellular basis of human intelligence

Goriounova, N. A.; Heyer, D. B.; Wilbers, R.; Verhoog, M. B.; Giugliano, M.; Verbist, C.; Obermayer, J.; Kerkhofs, A.; Smeding, H.; Verberne, M.; Idema, S.; Baayen, J. C.; Pieneman, A. W.; de Kock, C. P. J.; Klein, M.; Mansvelder, H. D.

10.1101/296343 — neuroscience — Posted on 2018-04-06

1688 The 100-plus Study of Dutch cognitively healthy centenarians: rationale, design and cohort description

Holstege, H.; Beker, N.; Dijkstra, T.; Pieterse, K.; Wemmenhove, E.; Schouten, K.; Thiessens, L.; Horsten, D.; Rechtuijt, S.; Sikkes, S.; van Poppel, F.; Meijers-Heijboer, H.; Hulsman, M.; Scheltens, P.

10.1101/295287 — neuroscience — Posted on 2018-04-06

1689 Targeted Gene Bisulfite Sequencing Identifies Differential Methylation in p21

Kolli, R. T.; Glenn, T. C.; Brown, B. T.; Barnett, L. M.; Lash, L. H.; Cummings, B.

10.1101/291732 — molecular biology — Posted on 2018-04-06

1690 Intracellular signaling through the comRS system in Streptococcus mutans genetic competence

Underhill, S. A. M.; Shields, R. C.; Kaspar, J. R.; Haider, M.; Burne, R. A.; Hagen, S. J.

10.1101/291088 — microbiology — Posted on 2018-04-06

1691 The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing

Begolo, D.; Vincent, I. M.; Giordani, F.; Witty, M. J.; Rowan, T. G.; Bengaly, Z.; Gillingwater, K.; Freund, Y.; Barrett, M. P.; Clayton, C. E.

10.1101/295550 — microbiology — Posted on 2018-04-06

1692 Detection and removal of barcode swapping in single-cell RNA-seq data

Griffiths, J. A.; Richard, A. C.; Bach, K.; Lun, A. T. L.; Marioni, J. C.

10.1101/177048 — genomics — Posted on 2018-04-06

1693 Experimental assay of a fitness landscape on a macroevolutionary scale

Pokusaeva, V.; Usmanova, D.; Putintseva, E.; Espinar, L.; Sarkisyan, K.; Mishin, A.; Bogatyreva, N.; Ivankov, D.; Filion, G.; Carey, L.; Kondrashov, F. A.

10.1101/222778 — evolutionary biology — Posted on 2018-04-06

1694 Graph Peak Caller: calling ChIP-Seq Peaks on Graph-based Reference Genomes

Grytten, I.; Rand, K. D.; Nederbragt, A. J.; Storvik, G. O.; Glad, I. K.; Sandve, G. K.

10.1101/286823 — bioinformatics — Posted on 2018-04-06

1695 Molecular architecture of the mouse nervous system

Zeisel, A.; Hochgerner, H.; Lonnerberg, P.; Johnsson, A.; Memic, F.; van der Zwan, J.; Haring, M.; Braun, E.; Borm, L.; La Manno, G.; Codeluppi, S.; Furlan, A.; Skene, N.; Harris, K. D.; Hjerling Leffler, J.; Arenas, E.; Ernfors, P.; Marklund, U.; Linnarsson, S.

10.1101/294918 — neuroscience — Posted on 2018-04-06

1696 Better than maximum likelihood estimation of model-based and model-free learning style

Yazdani, S.; Vahabie, A.-H.; Nadjar Araabi, B.; Nili Ahmadabadi, M.

10.1101/296335 — neuroscience — Posted on 2018-04-06

1697 Population structure of Borrelia garinii from Ixodes uriae collected in seabird colonies of the northwestern Atlantic Ocean

Munro, H. J.; Ogden, N. H.; Mechai, S.; Lindsay, L. R.; Robertson, G. J.; Whitney, H.; Lang, A. S.

10.1101/296319 — microbiology — Posted on 2018-04-06

1698 The impact of endogenous retroviruses on nuclear organization and gene expression

Raviram, R.; Rocha, P.; Luo, V.; Swanzey, E.; Miraldi, E.; Chuong, E.; Feschotte, C.; Bonneau, R.; Skok, J.

10.1101/295329 — genomics — Posted on 2018-04-06

1699 Small RNA-mediated genomic silencing promotes telomere stability in the absence of telomerase

Longtine, C.; Frenk, S.; Ahmed, S.

10.1101/292722 — genetics — Posted on 2018-04-06

1700 Modeling cell-substrate de-adhesion dynamics under fluid shear

Maan, R.; Rani, G.; Menon, G. I.; Pullarkat, P. A.

10.1101/166371 — biophysics — Posted on 2018-04-06

1701 Cold acclimation of Trogoderma granarium Everts is tightly linked to regulation of enzyme activity, energy content and ion concentration

Mohammadzadeh, M.; Izadi, H.

10.1101/296467 — molecular biology — Posted on 2018-04-06

1702 EWI-2 Inhibits Cell-Cell Fusion at the Virological Synapse

Whitaker, E. E.; Symeonides, M.; Munson, P. B.; Thali, M.

10.1101/296251 — microbiology — Posted on 2018-04-06

1703 Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility

Johansen, M. D.; Hortle, E.; Kasparian, J.; Romero, A.; Novoa, B.; Figueras, A.; Britton, W. J.; de Silva, K.; Purdie, A. C.; Oehlers, S. H.

10.1101/250548 — immunology — Posted on 2018-04-06

1704 Bivariate genome-wide association analysis strengthens the role of bitter receptor clusters on chromosomes 7 and 12 in human bitter taste

Hwang, L.-D.; Gharahkhani, P.; Breslin, P. A. S.; Gordon, S. D.; Zhu, G.; Martin, N. G.; Reed, D. R.; Wright, M. J.

10.1101/296269 — genetics — Posted on 2018-04-06

1705 Environmental sources of bacteria and genetic variation in behavior influence host-associated microbiota

Mushegian, A. A.; Arbore, R.; Walser, J.-C.; Ebert, D.

10.1101/296228 — evolutionary biology — Posted on 2018-04-06

1706 Convergence of socio-ecological dynamics in disparate ecological systems under strong coupling to human social systems

Sigdel, R.; Anand, M.; Bauch, C.

10.1101/296202 — ecology — Posted on 2018-04-06

1707 Rearing temperature and fatty acid supplementation jointly affect membrane fluidity and heat tolerance in Daphnia

Martin-Creuzburg, D.; Coggins, B. L.; Ebert, D.; Yampolsky, L. Y.

10.1101/295998 — ecology — Posted on 2018-04-06

1708 An intrinsic cell cycle timer terminates limb bud outgrowth

Pickering, J.; Chinnaiya, K.; Rich, C. A.; Saiz-Lopez, P.; Ros, M. A.; Towers, M.

10.1101/296350 — developmental biology — Posted on 2018-04-06

1709 Synaptobrevin-2 C-terminal Flexible Region Regulates the Discharge of Catecholamine.

Weiss, A. N.

10.1101/296582 — biophysics — Posted on 2018-04-06

1710 Reliable individual differences in fine-grained cortical functional architecture

Feilong, M.; Nastase, S. A.; Guntupalli, J. S.; Haxby, J. V.

10.1101/296012 — neuroscience — Posted on 2018-04-06

1711 Prefrontal cortex as a meta-reinforcement learning system

Wang, J. X.; Kurth-Nelson, Z.; Kumaran, D.; Tirumala, D.; Soyer, H.; Leibo, J. Z.; Hassabis, D.; Botvinick, M.

10.1101/295964 — neuroscience — Posted on 2018-04-06

1712 Convolutional neural network models of V1 responses to complex patterns

Zhang, Y.; Lee, T. S.; Li, M.; Liu, F.; Tang, S.

10.1101/296301 — neuroscience — Posted on 2018-04-06

1713 Global changes in mRNA abundance drive differential shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription

Gilbertson, S.; Federspiel, J. D.; Hartenian, E.; Cristea, I. M.; Glaunsinger, B.

10.1101/295972 — molecular biology — Posted on 2018-04-06

1714 Golgi Renaissance: the pivotal role of the largest Golgi protein giantin

Petrosyan, A.; Manca, S.; Casey, C.; Thomes, P.; Riethoven, J.-J.; Clarke, J.

10.1101/296517 — cell biology — Posted on 2018-04-06

1715 Accurate differential analysis of transcription factor activity from gene expression

Amin, V.; Cobanoglu, M. C.

10.1101/296210 — bioinformatics — Posted on 2018-04-06

1716 GlucoPush: A Do-It-Yourself Add-On for Online Tracking of Personal Glucometer Use

Soenksen, L. R.; Mamat, Z.

10.1101/296293 — bioengineering — Posted on 2018-04-06

1717 Conversion of iPS derived hepatic progenitors into scalable, functional and developmentally relevant human organoids using an inverted colloidal crystal poly (ethylene glycol) scaffold engineered from collagen-coated pores of defined size

Ng, S. S.; Saeb-Parsy, K.; Segal, J. M.; Serra, M. P.; Blackford, S. J. I.; Horcas Lopez, M.; No, D. Y.; Frank, C. W.; Cho, N. J.; Nakauchi, H.; Glenn, J. S.; Rashid, S. T.

10.1101/296327 — bioengineering — Posted on 2018-04-06

1718 Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis

Kim, S.-H.; Redvers, R. P.; Chi, L. H.; Ling, X.; Lucke, A. J.; Reid, R. C.; Fairlie, D.; Baptista Moreno Martin, A. C.; Anderson, R. L.; Denoyer, D.; Pouliot, N.

10.1101/296384 — cancer biology — Posted on 2018-04-06

1719 Development of a GFP Fluorescent Bacterial Biosensor for the Detection and Quantification of Silver and Copper Ions

Martinez, A. R.; Heil, J. R.; Charles, T. C.

10.1101/296079 — synthetic biology — Posted on 2018-04-06

1720 Mechanisms for action prediction operate differently in observers with motor experience

Colling, L. J.; Thompson, W. F.; Sutton, J.

10.1101/044438 — neuroscience — Posted on 2018-04-06

1721 Pathological Oxidation of PTPN12 Underlies ABL1 Phosphorylation in HLRCC

Xu, Y.; Taylor, P.; Andrade, J.; Ueberheide, B.; Shuch, B.; Glazer, P. M.; Bindra, R. S.; Moran, M. F.; Linehan, M.; Neel, B. G.

10.1101/296194 — cancer biology — Posted on 2018-04-06

1722 Evolutionary dynamics of sex chromosomes of palaeognathous birds

Xu, L.; Sin, S. Y. W.; Grayson, P.; Janes, D. E.; Edwards, S. V.; Sackton, T. B.

10.1101/295089 — evolutionary biology — Posted on 2018-04-05

1723 Decline in pneumococcal disease in unimmunized adults is associated with vaccine-associated protection against colonization in toddlers and preschool-aged children

Weinberger, D. M.; Pitzer, V. E.; Regev-Yochay, G.; Givon-Lavi, N.; Dagan, R.

10.1101/293266 — epidemiology — Posted on 2018-04-05

1724 Off-target inhibition by active site-targeting SHP2 inhibitors

Tsutsumi, R.; Ran, H.; Neel, B. G.

10.1101/295170 — cell biology — Posted on 2018-04-05

1725 Digitally-Supported Continuous Care Intervention Including Individualized Nutritional Ketosis Significantly Improves Surrogate Markers of Non-Alcoholic Fatty Liver Disease (NAFLD) and Liver Fibrosis in Patients with Type 2 Diabetes: An Open Label, Non-Randomized, Controlled Study

Vilar-Gomez, E.; Athinarayanan, S. J.; Hallberg, S. J.; Bhanpuri, N. H.; McKenzie, A. L.; Campbell, W. W.; McCarter, J. P.; Phinney, S. D.; Volek, J. S.; Chalasani, N.

10.1101/293548 — clinical trials — Posted on 2018-04-05

1726 Polygonal motion and adaptable phototaxis via flagellar beat switching in Euglena gracilis

Tsang, A. C. H.; Lam, A. T.; Riedel-Kruse, I. H.

10.1101/292896 — biophysics — Posted on 2018-04-05

1727 Emergence and global spread of a multidrug-resistant, community-associated MRSA lineage from the Indian subcontinent

Steinig, E. J.; Duchene, S.; Robinson, D. A.; Monecke, S.; Yokoyama, M.; Laabei, M.; Slickers, P.; Andersson, P.; Williamson, D.; Kearns, A.; Goering, R.; Dickson, E.; Ehricht, R.; Ip, M.; O'Sullivan, M. V.; Coombs, G. W.; Petersen, A.; Brennan, G.; Shore, A. C.; Coleman, D. C.; Pantosti, A.; de Lencastre, H.; Westh, H.; Kobayashi, N.; Heffernan, H.; Strommenger, B.; Layer, F.; Weber, S.; Aamot, H.; Skakni, L.; Peacock, S. J.; Sarovich, D.; Giffard, P.; Harris, S.; Parkhill, J.; Massey, R. C.; Holden, M. T.; Bentley, S. D.; Tong, S. Y.

10.1101/233395 — microbiology — Posted on 2018-04-05

1728 Controlling load-dependent contractility of the heart at the single molecule level

Liu, C.; Kawana, M.; Song, D.; Ruppel, K. M.; Spudich, J.

10.1101/258020 — biophysics — Posted on 2018-04-05

1729 Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines

McCauley, S. M.; Kim, K.; Nowosielska, A.; Dauphin, A.; Diehl, W. E.; Luban, J.

10.1101/128447 — microbiology — Posted on 2018-04-05

1730 No evidence that more physically attractive young adult women have higher estradiol or progesterone

Jones, B. C.; Hahn, A. C.; Fisher, C. I.; Wang, H.; Kandrik, M.; Lao, J.; Han, C.; Lee, A. J.; Holzleitner, I. J.; DeBruine, L. M.

10.1101/136515 — animal behavior and cognition — Posted on 2018-04-05

1731 Size-reduced embryos reveal a gradient scaling based mechanism for zebrafish somite formation

Ishimatsu, K.; Hiscock, T. W.; Collins, Z. M.; Sari, D. W. K.; Lischer, K.; Richmond, D. L.; Bessho, Y.; Matsui, T.; Megason, S. G.

10.1101/211615 — developmental biology — Posted on 2018-04-05

1732 Community-driven data analysis training for biology

Batut, B.; Hiltemann, S.; Bagnacani, A.; Baker, D.; Bhardwaj, V.; Blank, C.; Bretaudeau, A.; Gueguen, L.; Cech, M.; Chilton, J.; Clements, D.; Doppelt-Azeroual, O.; Erxleben, A.; Freeberg, M.; Gladman, S.; Hoogstrate, Y.; Hotz, H.-R.; Houwaart, T.; Jagtap, P.; Lariviere, D.; Le Corguille, G.; Manke, T.; Mareuil, F.; Ramirez, F.; Ryan, D.; Sigloch, F.; Soranzo, N.; Wolff, J.; Videm, P.; Wolfien, M.; Wubuli, A.; Yusuf, D.; Backofen, R.; Taylor, J.; Nekrutenko, A.; Grüning, B.

10.1101/225680 — bioinformatics — Posted on 2018-04-05

1733 How familiarity warps representation in the face space

Chauhan, V.; Gobbini, M. I.

10.1101/293225 — neuroscience — Posted on 2018-04-05

1734 Phospholipid membranes promote the early stage assembly of α-synuclein aggregates

Lv, Z.; Hashemi, M.; Banerjee, S.; Zagorski, K.; Rochet, C.; Lyubchenko, Y. L.

10.1101/295782 — neuroscience — Posted on 2018-04-05

1735 Comparative Genome Analysis Reveals Important Genetic Factors Associated with Probiotic Property in Enterococcus faecium strains

Ghattargi, V. C.; Gaikwad, M. A.; Meti, B. S.; Nimonkar, Y. S.; Dixit, K.; Prakash, O.; Shouche, Y. S.; Dhotre, D.; Pawar, S. S.

10.1101/295881 — bioinformatics — Posted on 2018-04-05

1736 Remapping the cognitive and neural profiles of children who struggle at school

Astle, D. E.; Bathelt, J.; the CALM team, ; Holmes, J.

10.1101/295725 — neuroscience — Posted on 2018-04-05

1737 Training listeners to detect auditory-visual temporal coherence enhances their ability to exploit visual information for auditory scene analysis

Atilgan, H.; Bizley, J. K.

10.1101/295766 — neuroscience — Posted on 2018-04-05

1738 Development of the MAM model of schizophrenia in mice: Sex similarities and differences of prefrontal cortical and hippocampal function

CHALKIADAKI, K.; Velli, A.; Kyriazidis, E.; Stavroulaki, V.; Vouvoutsis, V.; Chatzaki, E.; Aivaliotis, M.; Sidiropoulou, K.

10.1101/295741 — neuroscience — Posted on 2018-04-05

1739 Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease

Stimmell, A. C.; Baglietto-Vargas, D.; Moseley, S. C.; Lapointe, V.; Thompson, L. M.; LaFerla, F. M.; McNaughton, B. L.; Wilber, A. A.

10.1101/258616 — neuroscience — Posted on 2018-04-05

1740 CCL3 promotes germinal center B cells sampling by follicular regulatory T cells and ensures optimal humoral response

Grigorova, I. L.; Benet, Z. L.; Ke, F.; Marthi, M.; Wu, R.; Turner, J. S.; Gabayre, J. B.; Ivanitskiy, M. I.; Sethi, S. S.

10.1101/295980 — immunology — Posted on 2018-04-05

1741 MEST induces epithelial-mesenchymal transition through IL-6/JAK/STAT3 signaling in breast cancers

Kim, M.; Lee, H. S.; Kim, Y. J.; Kang, S. G.; Lee, D. Y.; Jin, W.

10.1101/295832 — cancer biology — Posted on 2018-04-05

1742 When more is less: Dual phosphorylation protects signaling off-state against overexpression

Witzel, F.; Bluthgen, N.

10.1101/295899 — biophysics — Posted on 2018-04-05

1743 Equitable Thresholding and Clustering

Cox, R. W.

10.1101/295931 — bioinformatics — Posted on 2018-04-05

1744 Modeling the temporal dynamics of the gut microbial community in adults and infants

Shenhav, L.; Furman, O.; Briscoe, L.; Thompson, M.; Mizrahi, I.; Halperin, E.

10.1101/212993 — microbiology — Posted on 2018-04-05

1745 Variation in competitive ability with mating system, ploidy and range expansion in four Capsella species

Yang, X.; Lascoux, M.; Glemin, S.

10.1101/214866 — evolutionary biology — Posted on 2018-04-05

1746 Identifying controllable and uncontrollable dynamical behavior in complex networks

Rozum, J. C.; Albert, R.

10.1101/236323 — systems biology — Posted on 2018-04-05

1747 Differentiation of Alzheimer’s disease based on local and global parameters in personalized Virtual Brain models

Zimmermann, J.; Perry, A.; Breakspear, M.; Schirner, M.; Sachdev, P.; Wen, W.; Kochan, N. A.; Mapstone, M.; Ritter, P.; McIntosh, A. R.; Solodkin, A.

10.1101/277624 — neuroscience — Posted on 2018-04-05

1748 Towards automation of germline variant curation inclinical cancer genetics

Ravichandran, V.; Shameer, Z.; Kemel, Y.; Walsh, M.; Cadoo, K.; Lipkin, S.; Mandelker, D.; Zhang, L.; Stadler, Z.; Robson, M.; Offit, K.; Joseph, V.

10.1101/295865 — genetics — Posted on 2018-04-05

1749 An analytical framework for understanding regulatory novelty accompanying allopolyploidization

Hu, G.; Wendel, J. F.

10.1101/212092 — evolutionary biology — Posted on 2018-04-05

1750 Sensory neuropathy-causing mutations in ATL3 cause aberrant ER membrane tethering

Krols, M.; Detry, S.; Asselbergh, B.; Almeida-Souza, L.; Kremer, A.; Lippens, S.; de Rycke, R.; De Winter, V.; Müller, F.-J.; Kurth, I.; McMahon, H. T.; Savvides, S. N.; Timmerman, V.; Janssens, S.

10.1101/192484 — cell biology — Posted on 2018-04-05

1751 Target variant detection in leukemia using unaligned RNA-Seq reads

Audemard, E.; Gendron, P.; Lavallee, V.-P.; Hebert, J.; Sauvageau, G.; Lemieux, S.

10.1101/295808 — bioinformatics — Posted on 2018-04-05

1752 bioLQM: a java library for the manipulation and conversion of Logical Qualitative Models of biological networks

Naldi, A.

10.1101/287011 — systems biology — Posted on 2018-04-05

1753 MYC Dysregulates Mitotic Spindle Function Creating a Dependency on TPX2

Rohrberg, J.; Corella, A.; Taileb, M.; Kilinc, S.; Jokisch, M.-L.; Camarda, R.; Zhou, A.; Balakrishnan, S.; Chang, A. N.; Goga, A.

10.1101/272336 — cell biology — Posted on 2018-04-05

1754 PDX Finder: A Portal for Patient-Derived tumor Xenograft Model Discovery

Conte, N.; Mason, J.; Halmagyi, C.; Neuhauser, S. B.; Mosaku, A.; Begley, D. A.; Krupke, D. M.; Parkinson, H.; Meehan, T.; Bult, C. J.

10.1101/291443 — cancer biology — Posted on 2018-04-05

1755 Data-driven brain-types and their cognitive consequences

Bathelt, J.; Johnson, A.; Zhang, M.; the CALM team, ; Astle, D. E.

10.1101/237859 — neuroscience — Posted on 2018-04-05

1756 LET-99-dependent spatial restriction of active force generators makes spindle’s position robust

Bouvrais, H.; Chesneau, L.; Pastezeur, S.; Delattre, M.; Pecreaux, J.

10.1101/103937 — biophysics — Posted on 2018-04-05

1757 Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells

Miraldi, E. R.; Pokrovskii, M.; Watters, A.; Castro, D. M.; De Veaux, N.; Hall, J. A.; Lee, J.-Y.; Ciofani, M.; Madar, A.; Carriero, N.; Littman, D. R.; Bonneau, R.

10.1101/292987 — systems biology — Posted on 2018-04-05

1758 Anatomical predictors of successful prism adaptation in chronic visual neglect

Lunven, M.; Rode, G.; Bourlon, C.; Duret, C.; Migliaccio, R.; Chevrillon, E.; Thiebaut de Schotten, M.; Bartolomeo, P.

10.1101/144956 — neuroscience — Posted on 2018-04-05

1759 Polygenic risk scores for major depressive disorder and neuroticism as predictors of antidepressant response: meta-analysis of three treatment cohorts.

Ward, J.; Graham, N.; Strawbridge, R.; Ferguson, A.; Jenkins, G.; Chen, W.; Frye, M.; Weinshilboum, R.; Uher, R.; Lewis, C. M.; Biernacka, J.; Smith, D. J.

10.1101/295717 — genetics — Posted on 2018-04-05

1760 theseus - An R package for the analysis and visualization of microbial community data

Price, J. R.; Woloszynek, S.; Rosen, G. L.; Sales, C. M.

10.1101/295675 — ecology — Posted on 2018-04-05

1761 Evaluating metabarcoding to analyse diet composition of species foraging in anthropogenic landscapes using Ion Torrent and Illumina sequencing

FORIN-WIART, M.-A.; Galan, M.; Piry, S.; Cosson, J.-F.; Larose, C.; Poulle, M.-L.

10.1101/295758 — molecular biology — Posted on 2018-04-05

1762 Clustering de Novo by Gene of Long Reads from Transcriptomics Data

Marchet, C.; Lecompte, L.; Da Silva, C.; Cruaud, C.; Aury, J. M.; Nicolas, J.; Peterlongo, P.

10.1101/170035 — bioinformatics — Posted on 2018-04-05

1763 Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

Kunkle, B. W.; Grenier-Boley, B.; Sims, R.; Bis, J. C.; Naj, A. C.; Boland, A.; Vronskaya, M.; van der Lee, S. J.; Amlie-Wolf, A.; Bellenguez, C.; Frizatti, A.; Chouraki, V.; Alzheimer's Disease Genetics Consortium (ADGC), ; European Alzheimer's Disease Initiative (EADI), ; Cohorts for Heart and Aging Research in Genomic Epidemiology Consortium (CHARGE), ; Genetic and Environmental Risk in Alzheimer's Disease Consortium (GERAD/PERADES), ; Schmidt, H.; Hakonarson, H.; Munger, R.; Schmidt, R.; Farrer, L. A.; Van Broeckhoven, C.; O'Donovan, M. C.; Destefano, A. L.; Jones, L.; Haines, J. L

10.1101/294629 — genetics — Posted on 2018-04-05

1764 Minimizing Structural Bias in Single-Molecule Super-Resolution Microscopy

Mazidi, H.; Lu, J.; Nehorai, A.; Lew, M. D.

10.1101/293670 — bioinformatics — Posted on 2018-04-05

1765 Cross-type Biomedical Named Entity Recognition with Deep Multi-Task Learning

Wang, X.; Zhang, Y.; Ren, X.; Zhang, Y.; Zitnik, M.; Shang, J.; Langlotz, C.; Han, J.

10.1101/256453 — bioinformatics — Posted on 2018-04-05

1766 Genome variants associated with RNA splicing variation in bovine are extensively shared between tissues

Xiang, R.; Hayes, B. J.; Vander Jagt, C. J.; MacLeod, I. M.; Khansefid, M.; Bowman, P. J.; Yuan, Z.; Prowse-Wilkins, C. P.; Reich, C. M.; Mason, B. A.; Garner, J. B.; Marett, L. C.; Chen, Y.; Bolormaa, S.; Daetwyler, H. D.; Chamberlain, A. J.; Goddard, M. E.

10.1101/220251 — genomics — Posted on 2018-04-05

1767 Persistent increases of PKMζ in sensorimotor cortex maintain procedural long-term memory storage

Gao, P. P.; Goodman, J. H.; Sacktor, T. C.; Francis, J. T.

10.1101/193508 — neuroscience — Posted on 2018-04-05

1768 Earthworms and Cadmium - heavy metal resistant gut bacteria as indicators for heavy metal pollution in soils?

Srut, M.; Menke, S.; Höckner, M.; Sommer, S.

10.1101/295444 — microbiology — Posted on 2018-04-05

1769 Evolution of the latitudinal diversity gradient in the hyperdiverse ant genus Pheidole

Economo, E. P.; Huang, J.-P.; Fischer, G.; Sarnat, E. M.; Narula, N.; Janda, M.; Guenard, B.; Longino, J. T.; Knowles, L. L.

10.1101/295386 — evolutionary biology — Posted on 2018-04-05

1770 Molecular basis for voltage sensitivity in membrane proteins

Kasimova, M. A.; Lindahl, E.; Delemotte, L.

10.1101/295816 — biophysics — Posted on 2018-04-05

1771 Expressed vomeronasal type-1 receptors (V1rs) in bats uncover conserved mechanisms of social chemical signaling

Yohe, L. R.; Davies, K. T.; Rossiter, S. J.; Davalos, L.

10.1101/293472 — evolutionary biology — Posted on 2018-04-05

1772 Design Principles for Autonomous Illumination Control in Localization Microscopy

Stefko, M.; Ottino, B.; Douglass, K. M.; Manley, S.

10.1101/295519 — biophysics — Posted on 2018-04-05

1773 A multiplexed homology-directed DNA repair assay reveals the impact of ~1,700 BRCA1 variants on protein function

Starita, L. M.; Islam, M. M.; Banerjee, T.; Adamovich, A. I.; Gullingsrud, J.; Fields, S.; Shendure, J.; Parvin, J. D.

10.1101/295279 — genomics — Posted on 2018-04-05

1774 Spontaneous activity emerging from an inferred network model captures complex temporal dynamics of spiking data

Capone, C.; Gigante, G.; Del Giudice, P.

10.1101/292862 — neuroscience — Posted on 2018-04-05

1775 Epigenomic and functional dynamics of human bone marrow myeloid differentiation to mature blood neutrophils

Grassi, L.; Pourfarzad, F.; Ullrich, S.; Merkel, A.; Were, F.; Carrillo de Santa Pau, E.; Yi, G.; Hiemstra, I. H.; Tool, A. T. J.; Mul, E.; Perner, J.; Janssen-Megens, E.; Berentsen, K.; Kerstens, H.; Habibi, E.; Gut, M.; Yaspo, M. L.; Linser, M.; Lowy, E.; Datta, A.; Clarke, L.; Flicek, P.; Vingron, M.; Roos, D.; van den Berg, T. K.; Heath, S.; Rico, D.; Frontini, M.; Kostadima, M.; Gut, I.; Valencia, A.; Ouwehand, W. H.; Stunnenberg, H. G.; Martens, J. H. A.; Kuijpers, T. W.

10.1101/295014 — immunology — Posted on 2018-04-05

1776 The Effect of Productive HPV16 Infection on Global Gene Expression of Cervical Epithelium

Kang, S. D.; Chatterjee, S.; Alam, S.; Salzberg, A. C.; Milici, J.; van der Burg, S. H.; Meyers, C.

10.1101/295402 — genomics — Posted on 2018-04-05

1777 TAC-seq: targeted DNA and RNA sequencing for precise biomarker molecule counting

Teder, H.; Koel, M.; Paluoja, P.; Jatsenko, T.; Rekker, K.; Laisk-Podar, T.; Kukuskina, V.; Velthut-Meikas, A.; Zilina, O.; Peters, M.; Kere, J.; Salumets, A.; Palta, P.; Krjutskov, K.

10.1101/295253 — genomics — Posted on 2018-04-05

1778 Robustness of bristle number to temperature and genetic background varies with bristle type and is regulated by miR-9a.

Matamoro-Vidal, A.; Tully, T.; Courtier-Orgogozo, V.

10.1101/295485 — genetics — Posted on 2018-04-05

1779 Off-target inhibition by active site-targeting SHP2 inhibitors

Tsutsumi, R.; Ran, H.; Neel, B. G.

10.1101/295170 — cell biology — Posted on 2018-04-05

1780 Influence of pathway topology and functional class on the molecular evolution of human metabolic genes

Montanucci, L.; Laayouni, H.; Dobon, B.; Keys, K. L.; Bertranpetit, J.; Pereto, J.

10.1101/292714 — systems biology — Posted on 2018-04-05

1781 Benchmarking optimization methods for parameter estimation in large kinetic models

Villaverde, A. F.; Froehlich, F.; Weindl, D.; Hasenauer, J.; Banga, J. R.

10.1101/295006 — systems biology — Posted on 2018-04-05

1782 Bibliometric analysis of the trends of Zika related research from 2015 to 2017

Gwon, Y.-D.; Evander, M.

10.1101/287169 — scientific communication and education — Posted on 2018-04-05

1783 The cholinergic pesticide imidacloprid impairs contrast and direction sensitivity in motion detecting neurons of an insect pollinator

Rigosi, E.; O'Carroll, D. C.

10.1101/295576 — neuroscience — Posted on 2018-04-05

1784 Molecular architecture of the mouse nervous system

10.1101/294918 — neuroscience — Posted on 2018-04-05

1785 Cdt1 variants reveal unanticipated aspects of interactions with Cyclin/CDK and MCM important for normal genome replication.

Pozo, P. N.; Matson, J. P.; Cole, Y.; Kedziora, K.; Grant, G.; Temple, B.; Cook, J. G.

10.1101/295212 — molecular biology — Posted on 2018-04-05

1786 Adaptive periodicity in the infectivity of malaria gametocytes to mosquitoes

Schneider, P.; Rund, S. S. C.; Smith, N. L.; Prior, K. F.; O'Donnell, A. J.; Reece, S. E.

10.1101/294942 — microbiology — Posted on 2018-04-05

1787 Population dynamics of Escherichia coli in the gastrointestinal tracts of Tanzanian children

Richter, T. K. S.; Hazen, T. H.; Lam, D.; Coles, C. L.; Seidman, J. C.; You, Y.; Silbergeld, E. K.; Fraser, C. M.; Rasko, D. A.

10.1101/294934 — microbiology — Posted on 2018-04-05

1788 Peptide-binding groove contraction linked to the lack of T-cell response: Using complex structure and energy to identify neoantigens

Pang, Y.-P.; Elsbernd, L. R.; Block, M. S.; Markovic, S. N.

10.1101/295360 — immunology — Posted on 2018-04-05

1789 Genetic variation/evolution and differential host responses resulting from in-patient adaptation of Mycobacterium avium

Kannan, N.; Lai, Y.-P.; Haug, M.; Lilleness, K.; Bakke, S.; Marstad, A.; Hov, H.; Naustdal, T.; Afset, J. E.; Ioerger, T.; Flo, T. H.; Steigedal, M.

10.1101/295121 — immunology — Posted on 2018-04-05

1790 Accurate functional classification of thousands of BRCA1 variants with saturation genome editing

Findlay, G. M.; Daza, R. M.; Martin, B.; Zhang, M. D.; Leith, A. P.; Gasperini, M.; Janizek, J. D.; Huang, X.; Starita, L. M.; Shendure, J.

10.1101/294520 — genomics — Posted on 2018-04-05

1791 Deciphering human ribonucleoprotein regulatory networks

Mukherjee, N.; Wessels, H.-H.; Lebedeva, S.; Sajek, M.; Farazi, T.; Ghanbari, M.; Garzia, A.; Munteanu, A.; Mihailovic, A.; Spitzer, J.; Akat, K.; Tuschl, T.; Ohler, U.

10.1101/295097 — genomics — Posted on 2018-04-05

1792 Combination of novel and public RNA-seq datasets to generate an mRNA expression atlas for the domestic chicken

Bush, S. J.; Freem, L.; MacCallum, A. J.; O'Dell, J.; Wu, C.; Afrasiabi, C.; Psifidi, A.; Stevens, M. P.; Smith, J.; Summers, K. M.; Hume, D. A.

10.1101/295535 — genomics — Posted on 2018-04-05

1793 Lipoprotein Signatures of Cholesteryl Ester Transfer Protein and HMG-CoA Reductase Inhibition

Kettunen, J.; Holmes, M. V.; Allara, E.; Anufrieva, O.; Ohukainen, P.; Oliver-Williams, C.; Tillin, T.; Hughes, A.; Kahonen, M.; Lehtimaki, T.; Viikari, J.; Raitakari, O.; Salomaa, V.; Jarvinen, M.-R.; Perola, M.; Davey Smith, G.; Chaturvedi, N.; Danesh, J.; Di Angelantonio, E.; Butterworth, A.; Ala-Korpela, M.

10.1101/295394 — genetics — Posted on 2018-04-05

1794 Inversion frequencies and phenotypic effects are modulated by the environment

Berdan, E.; Rosenquist, H.; Larson, K.; Wellenreuther, M.

10.1101/295568 — evolutionary biology — Posted on 2018-04-05

1795 The Fair Proportion is a Shapley Value on phylogenetic networks too

Coronado, T. M.; Riera, G.; Rossello, F.

10.1101/295592 — evolutionary biology — Posted on 2018-04-05

1796 Evolutionary dynamics of sex chromosomes of palaeognathous birds

Xu, L.; Sin, S. Y. W. Y. W.; Grayson, P.; Janes, D. E.; Edwards, S. V.; Sackton, T. B.

10.1101/295089 — evolutionary biology — Posted on 2018-04-05

1797 Evolution of Portulacineae marked by gene tree conflict and gene family expansion associated with adaptation to harsh environments

Wang, N.; Yang, Y.; Moore, M. J.; Brockington, S. F.; Walker, J. F.; Brown, J. W.; Liang, B.; Feng, T.; Edwards, C.; Mikenas, J.; Olivieri, J.; Hutchison, V.; Timoneda, A.; Stoughton, T.; Puente, R.; Majure, L.; Eggli, U.; Smith, S. A.

10.1101/294546 — evolutionary biology — Posted on 2018-04-05

1798 Discrimination of Gram-Positive versus Gram-Negative Bacteria by the Social Amoeba Dictyostelium discoideum

Rashidi, G.; Ostrowski, E.

10.1101/199471 — evolutionary biology — Posted on 2018-04-05

1799 Proteomic and Evolutionary Analyses of Sperm Activation Identify Uncharacterized Genes in Caenorhabditis Nematodes

Kasimatis, K. R.; Moerdyk-Schauwecker, M. J.; Timmermeyer, N.; Phillips, P. C.

10.1101/290221 — evolutionary biology — Posted on 2018-04-05

1800 Diverse progenitor cells preserve salivary gland ductal architecture after radiation induced damage

May, A.; Cruz Pacheco, N.; Emmerson, E.; Siedel, K.; Nathan, S.; Muench, M. O.; Klein, O. D.; Knox, S. M.

10.1101/295501 — developmental biology — Posted on 2018-04-05

1801 Lysosome enlargement during inhibition of the lipid kinase PIKfyve proceeds through lysosome coalescence

Choy, C. H.; Saffi, G.; Gray, M. A.; Wallace, C.; Dayam, R. M.; Ou, Z.-Y. A.; Lenk, G.; Puertollano, R.; Watkins, S. C.; Botelho, R. J.

10.1101/295246 — cell biology — Posted on 2018-04-05

1802 Personalized Regression Enables Sample-Specific Pan-Cancer Analysis

Lengerich, B.; Aragam, B.; Xing, E. P.

10.1101/294496 — bioinformatics — Posted on 2018-04-05

1803 xAtlas: Scalable small variant calling across heterogeneous next-generation sequencing experiments

Farek, J.; Hughes, D.; Mansfield, A.; Krasheninina, O.; Nasser, W.; Sedlazeck, F. J.; Khan, Z.; Venner, E.; Metcalf, G.; Boerwinkle, E.; Muzny, D. M.; Gibbs, R. A.; Salerno, W.

10.1101/295071 — bioinformatics — Posted on 2018-04-05

1804 Stratification of amyotrophic lateral sclerosis patients: a crowdsourcing approach

Kueffner, R.; Zach, N.; Bronfeld, M.; Norel, R.; Atassi, N.; Balagurusamy, V.; di Camillo, B.; Chio, A.; Cudkowicz, M.; Dillenberger, D.; Garcia-Garcia, J.; Hardiman, O.; Hoff, B.; Knight, J.; Leitner, M. L.; Li, G.; Mangravite, L.; Norman, T.; Wang, L.; The ALS Stratification Consortium, ; Xiao, J.; Fang, W.-C.; Peng, J.; Stolovitzky, G.

10.1101/294231 — bioinformatics — Posted on 2018-04-05

1805 Functional Analysis of Metagenomes by Likelihood Inference (FAMLI) Successfully Compensates for Multi-Mapping Short Reads from Metagenomic Samples

Golob, J. L.; Minot, S. S.

10.1101/295352 — bioinformatics — Posted on 2018-04-05

1806 Temporal Evolution of Cortical Ensembles Promoting Remote Memory Retrieval

DeNardo, L. A.; Liu, C. D.; Allen, W. E.; Adams, E. L.; Friedmann, D.; Dadgar-Kiani, E.; Fu, L.; Guenthner, C. J.; Lee, J. H.; Tessier-Lavigne, M.; Luo, L.

10.1101/295238 — neuroscience — Posted on 2018-04-05

1807 Secondary neurulation-fated cells in the tail bud undergo self-renewal and tubulogenesis regulated by a Sox2 gradient

Kawachi, T.; Shimokita, E.; Tadokoro, R.; Takahashi, Y.

10.1101/295709 — developmental biology — Posted on 2018-04-05

1808 Active presynaptic ribosomes in mammalian brain nerve terminals, and increased transmitter release after protein synthesis inhibition

Scarnati, M. S.; Kataria, R.; Biswas, M.; Paradiso, K. G.

10.1101/295543 — cell biology — Posted on 2018-04-05

1809 Timely double-strand break repair and pathway choice in pericentromeric heterochromatin depend on the histone demethylase dKDM4A

Janssen, A.; Colmenares, S. U.; Lee, T.; Karpen, G. H.

10.1101/295220 — cell biology — Posted on 2018-04-05

1810 Enhanced super-resolution microscopy by extreme value based emitter recovery

Ma, H.; Jiang, W.; Xu, J.; Liu, Y.

10.1101/295261 — cell biology — Posted on 2018-04-05

1811 Auxiliary subunits keep AMPA receptors compact during activation and desensitization

Baranovic, J.; Plested, A. J. R.

10.1101/295105 — biophysics — Posted on 2018-04-05

1812 Spatial Self-Organization Resolves Conflicts Between Individuality and Collective Migration

Fu, X.; Kato, S.; Long, J.; Mattingly, H. H.; He, C.; Vural, D. C.; Zucker, S. W.; Emonet, T.

10.1101/295196 — biophysics — Posted on 2018-04-05

1813 Population-level distribution and putative immunogenicity of cancer neoepitopes

Wood, M. A.; Paralkar, M.; Paralkar, M. P.; Nguyen, A.; Struck, A. J.; Ellrott, K.; Margolin, A.; Nellore, A.; Thompson, R. F.

10.1101/192716 — cancer biology — Posted on 2018-04-04

1814 Uniform distribution of 35S promoter-driven mDII auxin control sensor in leaf primordia

Guan, C.; Du, F.; Jiao, Y.

10.1101/293753 — plant biology — Posted on 2018-04-04

1815 Functional repair after ischemic injury through high efficiency in situ astrocyte-to-neuron conversion

Chen, Y.; Chen, G.; Ma, N.; Pei, Z.; Wu, Z.; Do-Monte, F. H.; Huang, P.; Yellin, E.; Chen, M.; Yin, J.; Lee, G.; Minier, A.; Hu, Y.; Bai, Y.; Lee, K.; Quirk, G.

10.1101/294967 — neuroscience — Posted on 2018-04-04

1816 From head to tail: A neuromechanical model of forward locomotion in C. elegans

Izquierdo, E. J.; Beer, R. D.

10.1101/295154 — neuroscience — Posted on 2018-04-04

1817 All-in-One Adeno-associated Virus Delivery and Genome Editing by Neisseria meningitidis Cas9 in vivo

Ibraheim, R.; Song, C.-Q.; Mir, A.; Amrani, N.; Xue, W.; Sontheimer, E. J.

10.1101/295055 — molecular biology — Posted on 2018-04-04

1818 Prion protein quantification in cerebrospinal fluid as a tool for prion disease drug development

Vallabh, S. M.; Nobuhara, C. K.; Llorens, F.; Zerr, I.; Parchi, P.; Capellari, S.; Kuhn, E.; Klickstein, J.; Safar, J.; Nery, F.; Swoboda, K.; Schreiber, S. L.; Geschwind, M. D.; Zetterberg, H.; Arnold, S. E.; Minikel, E. V.

10.1101/295063 — molecular biology — Posted on 2018-04-04

1819 Manganese oxide biomineralization is a social trait protecting against nitrite toxicity

Zerfass, C.; Christie-Oleza, J. A.; soyer, o.

10.1101/294975 — microbiology — Posted on 2018-04-04

1820 High prevalence of S. pyogenes Cas9-specific T cell sensitization within the adult human population - A balanced effector/regulatory T cell response

Wagner, D. L.; Amani, L.; Wendering, D. J.; Reinke, P.; Volk, H.-D.; Schmueck-Henneresse, M.

10.1101/295139 — immunology — Posted on 2018-04-04

1821 Circadian protein regulation in the green lineage I. A phospho-dawn anticipates light onset before proteins peak in daytime.

Noordally, Z. B.; Hindle, M. M.; Martin, S. F.; Seaton, D. D.; Simpson, I.; Le Bihan, T.; Millar, A. J.

10.1101/287862 — plant biology — Posted on 2018-04-04

1822 Contribution of non-coding mutations to RPGRIP1-mediated inherited retinal degeneration.

Jamshidi, F.; Place, E. M.; Mehrotra, S.; Navarro-Gomez, D.; Maher, M.; Valkanas, E.; Cherry, T. J.; Lek, M.; MacArthur, D.; Pierce, E. A.; Bujakowska, K. M.

10.1101/211292 — genomics — Posted on 2018-04-04

1823 Effects of exclusive breastfeeding on infant gut microbiota: a meta-analysis across studies and populations

Ho, N. T.; Li, F.; Lee-Sarwar, K. A.; Tun, H. M.; Brown, B.; Pannaraj, P. S.; Bender, J. M.; Azad, M. B.; Thompson, A. L.; Weiss, S. T.; Azcarate-Peril, M. A.; Litonjua, A. A.; Kozyrskyj, A. L.; Jaspan, H. B.; Aldrovandi, G. M.; Kuhn, L.

10.1101/292755 — microbiology — Posted on 2018-04-04

1824 Inferring Disease Risk Genes from Sequencing Data in Multiplex Pedigrees Through Sharing of Rare Variants

Bureau, A.; Begum, F.; Taub, M. A.; Hetmanski, J.; Parker, M. M.; Albacha-Hejazi, H.; Scott, A. F.; Murray, J. C.; Marazita, M. L.; Bailey-Wilson, J. E.; Beaty, T. H.; Ruczinski, I.

10.1101/285874 — genetics — Posted on 2018-04-04

1825 Comparative demography elucidates the longevity of parasitic and symbiotic relationships.

Hecht, L. B. B.; Thompson, P. C.; Rosenthal, B. M.

10.1101/271965 — evolutionary biology — Posted on 2018-04-04

1826 Recurrent cortical circuits implement concentration-invariant odor coding

Bolding, K. A.; Franks, K. M.

10.1101/294132 — neuroscience — Posted on 2018-04-04

1827 Differential carbohydrate utilization and organic acid production by honey bee symbionts

Lee, F. J.; Miller, K. I.; McKinlay, J. B.; Newton, I. L. G.

10.1101/294249 — microbiology — Posted on 2018-04-04

1828 Visualizing multiple inter-organelle contact sites using the organelle-targeted split-GFP system

Kakimoto, Y.; Tashiro, S.; Kojima, R.; Morozumi, Y.; Endo, T.; Tamura, Y.

10.1101/290114 — cell biology — Posted on 2018-04-04

1829 Graph theory approaches to functional network organization in brain disorders: A critique for a brave new small-world

Hallquist, M. N.; Hillary, F. G.

10.1101/243741 — neuroscience — Posted on 2018-04-04

1830 Functional selectivity and specific connectivity of inhibitory neurons in primary visual cortex

Znamenskiy, P.; Kim, M.-H.; Muir, D. R.; Iacaruso, M. F.; Hofer, S. B.; Mrsic-Flogel, T. D.

10.1101/294835 — neuroscience — Posted on 2018-04-04

1831 Cytokinin perception in potato: New features of canonic players

Lomin, S. N.; Myakushina, Y. A.; Kolachevskaya, O. O.; Getman, I. A.; Arkhipov, D. V.; Savelieva, E. M.; Osolodkin, D. I.; Romanov, G. A.

10.1101/269266 — plant biology — Posted on 2018-04-04

1832 A T7 phage factor required for managing RpoS in Escherichia coli

Tabib-Salazar, A.; Liu, B.; Barker, D.; Burchell, L.; Qimron, U.; Matthews, S.; Wigneshweraraj, R.

10.1101/262279 — microbiology — Posted on 2018-04-04

1833 Evidence for a potential role of miR-1908-5p and miR-3614-5p in autoimmune disease risk using genome-wide analyses

Wohlers, I.; Bertram, L.; Lill, C.

10.1101/286260 — bioinformatics — Posted on 2018-04-04

1834 Mosaic Turner syndrome shows reduced phenotypic penetrance in an adult population study compared to clinically ascertained cases

Tuke, M. A.; Ruth, K. S.; Wood, A. R.; Beaumont, R. N.; Tyrrell, J.; Jones, S. E.; Yaghootkar, H.; Turner, C. L. S.; Donohoe, M. E.; Brooke, A. M.; Collinson, M. N.; Freathy, R. M.; Weedon, M. N.; Frayling, T. M.; Murray, A.

10.1101/177659 — genetics — Posted on 2018-04-04

1835 Regulator of calcineurin-2 is a centriolar protein with a role in cilia length control

Stevenson, N.; Bergen, D.; Xu, A.; Wyatt, E.; Henry, F.; McCaughey, J.; Vuolo, L.; Hammond, C.; Stephens, D.

10.1101/188946 — cell biology — Posted on 2018-04-04

1836 Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility

Johansen, M. D.; Hortle, E.; Kasparian, J.; Romero, A.; Novoa, B.; Figueras, A.; Britton, W.; de Silva, K.; Purdie, A. C.; Oehlers, S. H.

10.1101/250548 — immunology — Posted on 2018-04-04

1837 Systematic conservation planning for intraspecific genetic diversity.

Paz-Vinas, I.; Loot, G.; Hermoso, V.; Veyssiere, C.; Poulet, N.; Grenouillet, G.; Blanchet, S.

10.1101/105544 — ecology — Posted on 2018-04-04

1838 The synthetic histone-binding regulator protein PcTF activates interferon genes in breast cancer cells

Olney, K. C.; Nyer, D. B.; Vargas, D. A.; Wilson Sayres, M. A.; Haynes, K.

10.1101/186056 — synthetic biology — Posted on 2018-04-04

1839 WASABI: a dynamic iterative framework for gene regulatory network inference

Bonnaffoux, A.; Herbach, U.; Richard, A.; Guillemin, A.; Giraud, S.; Gros, P.-A.; Gandrillon, O.

10.1101/292128 — systems biology — Posted on 2018-04-04

1840 Native DNA electronics: the Nuclear Aggregates of Polyamines possible role

D'Agostino, L.

10.1101/294199 — cell biology — Posted on 2018-04-04

1841 Distinguishing cells from empty droplets in droplet-based single-cell RNA sequencing data

Lun, A.; Riesenfeld, S.; Andrews, T.; Dao, T. P.; Gomes, T.; participants in the 1st Human Cell Atlas Jamboree, ; Marioni, J.

10.1101/234872 — bioinformatics — Posted on 2018-04-04

1842 A unifying framework for joint trait analysis under a non-infinitesimal model

Johnson, R. D.; Shi, H.; Pasaniuc, B.; Sankararaman, S.

10.1101/293803 — bioinformatics — Posted on 2018-04-04

1843 Fusarium graminearum-Induced Shoot Elongation and Root Reduction in Maize Seedlings Correlate with Later Seedling Blight Severity

Zhou, S.; Bae, J. S.; Bergstrom, G. C.; Jander, G.

10.1101/287714 — plant biology — Posted on 2018-04-04

1844 CagY-dependent regulation of type IV secretion in Helicobacter pylori is associated with alterations in integrin binding

Skoog, E.; Morikis, V. A.; Martin, M. E.; Foster, G. A.; Cai, L. P.; Hansen, L. M.; Li, B.; Gaddy, J. A.; Simon, S.; Solnick, J. V.

10.1101/294769 — microbiology — Posted on 2018-04-04

1845 Emergence of mosaic plasmids harboring Tn1546-ermB element in Staphylococcus aureus isolates

Wan, T.-W.; Lin, Y.-T.; Hung, W.-C.; Tsai, J.-C.; Liu, Y.-J.; Hsueh, P.-R.; Teng, L.-J.

10.1101/294348 — microbiology — Posted on 2018-04-04

1846 RNA sequencing (RNA-seq) reveals extremely low levels of reticulocyte-derived globin gene transcripts in peripheral blood from horses (Equus caballus) and cattle (Bos taurus)

Correia, C. N.; McLoughlin, K. E.; Nalpas, N. C.; Magee, D. A.; Browne, J. A.; Rue-Albrecht, K.; Gordon, S. V.; MacHugh, D. E.

10.1101/294330 — genomics — Posted on 2018-04-04

1847 Robust single-cell DNA methylome profiling with snmC-seq2

10.1101/294355 — genomics — Posted on 2018-04-04

1848 (In)exhaustible suppliers for evolution? Epistatic selection tunes the adaptive potential of non-genetic inheritance

Rajon, E.; Charlat, S.

10.1101/294868 — evolutionary biology — Posted on 2018-04-04

1849 The Influence Of Social Behavior On Selection and Spread of Virulent Pathogen Strains

Pharaon, J.; Bauch, C.

10.1101/293936 — evolutionary biology — Posted on 2018-04-04

1850 Mettl14 is required for mouse post-implantation development by facilitating epiblast maturation

Sun, Q.-Y.; Meng, T. G.; Lu, X.; Guo, L.; Hou, G. M.; Li, Q. N.; Ma, X. S.; Huang, L.; Fan, L. H.; Zhao, Z. H.; Ou, X. H.; Ouyang, Y. C.; Schatten, H.; Li, L.; Wang, Z. B.

10.1101/294926 — developmental biology — Posted on 2018-04-04

1851 Mechanical unfold and transport of Green Florescent Protein through a nanopore

Shahzad, M. A.

10.1101/294819 — biophysics — Posted on 2018-04-04

1852 Universal kinetics for engagement of mechanosensing pathways in cell adhesion

Terentjev, E.; Bell, S.; Redmann, A.-L.

10.1101/292367 — biophysics — Posted on 2018-04-04

1853 The solvent-excluded surfaces of water-soluble proteins

Wang, L.

10.1101/294082 — bioinformatics — Posted on 2018-04-04

1854 The practical value of an explicit response model in quantitative uses of Biacore™ biosensors

Whyte, J. M.

10.1101/294843 — biochemistry — Posted on 2018-04-04

1855 Uncertainty quantification, propagation and characterization by Bayesian analysis combined with global sensitivity analysis applied to dynamical intracellular pathway models

Eriksson, O.; Jauhiainen, A.; Sasane, S. M.; Kramer, A.; Nair, A. G.; Sartorius, C.; Kotaleski, J. H.

10.1101/294884 — systems biology — Posted on 2018-04-04

1856 Plants with purple abaxial leaves: A repository of metrics from stomata distribution.

Almeida Filho, H. A.; Martinez Bruno, O.

10.1101/294553 — plant biology — Posted on 2018-04-04

1857 The biosynthetic origin of psychoactive kavalactones in kava

Pluskal, T.; Torrens-Spence, M. P.; Fallon, T. R.; De Abreu, A.; Shi, C. H.; Weng, J.-K.

10.1101/294439 — plant biology — Posted on 2018-04-04

1858 Pre-saccadic remapping relies on dynamics of spatial attention

Szinte, M.; Jonikaitis, D.; Rangelov, D.; Deubel, H.

10.1101/293886 — neuroscience — Posted on 2018-04-04

1859 Recurrent cortical circuits implement concentration-invariant odor coding

Bolding, K. A.; Franks, K. M.

10.1101/294132 — neuroscience — Posted on 2018-04-04

1860 Functional selectivity and specific connectivity of inhibitory neurons in primary visual cortex

Znamenskiy, P.; Kim, M.-H.; Muir, D. R.; Iacaruso, M. F.; Hofer, S. B.; Mrsic-Flogel, T. D.

10.1101/294835 — neuroscience — Posted on 2018-04-04

1861 Circadian clock neurons mediate time-of-day dependent responses to light

Jones, J. R.; Simon, T.; Lones, L.; Herzog, E. D.

10.1101/291955 — neuroscience — Posted on 2018-04-04

1862 Analysis of the Resuscitation-Availability of Viable-But-Nonculturable Cells of Vibrio parahaemolyticus upon Exposure to the Refrigerator Temperature

Yoon, J.-H.; Bae, Y.-M.; Rye, B.-Y.; Choi, C.; Moon, S.-G.; Lee, S.-Y.

10.1101/294751 — microbiology — Posted on 2018-04-04

1863 Bacillus licheniformis global nitrogen homeostatic regulator TnrA is a direct repressor of pgsBCAA transcription in Poly-γ-glutamic acid synthesis

Cai, D.; Chen, Y.; Wang, S.; Mo, F.; Ma, X.; Chen, S.

10.1101/294728 — microbiology — Posted on 2018-04-04

1864 Physiological Characteristics of Viable-but-nonculturable Vibrio parahaemolyticus upon Prolonged Exposure to the Refrigerator Temperature

Yoon, J.-H.; Lee, S.-Y.

10.1101/294744 — microbiology — Posted on 2018-04-04

1865 Toward a model-free feedback control synthesis for treating acute inflammation -- A mathematical perspective

Bara, O.; Fliess, M.; Join, C.; Day, J.; Djouadi, S. M.

10.1101/294389 — immunology — Posted on 2018-04-04

1866 Predicting humoral alloimmunity from differences in donor-recipient HLA surface electrostatic potential

Mallon, D. H.; Kling, C.; Robb, M.; Ellinghaus, E.; Bradley, J. A.; Taylor, C. J.; Kabelitz, D.; Kosmoliaptsis, V.

10.1101/294066 — immunology — Posted on 2018-04-04

1867 Fine-scale characterization of genomic structural variation in the human genome reveals adaptive and biomedically relevant hotspots

Lin, Y.-L.; Gokcumen, O.

10.1101/294322 — genomics — Posted on 2018-04-04

1868 Interdependence of linkage disequilibrium, chromatin architecture and compositional genome organization of mammals

Jabbari, K.; Wirtz, J.; Rauscher, M.; Wiehe, T.

10.1101/293837 — genomics — Posted on 2018-04-04

1869 Dissection of yeast pleiotropic drug resistance regulation reveals links between cell cycle regulation and control of drug pump expression

Li, J.; Kolberg, K.; Schlecht, U.; St. Onge, R. P.; Aparicio, A. M.; Horecka, J.; Davis, R. W.; Hillenmeyer, M. E.; Harvey, C.

10.1101/294579 — genetics — Posted on 2018-04-04

1870 Meta-analysis of genetic association with diagnosed Alzheimer’s disease identifies novel risk loci and implicates Abeta, Tau, immunity and lipid processing

10.1101/294629 — genetics — Posted on 2018-04-04

1871 foxr1 is a novel maternal-effect gene in fish that regulates embryonic cell growth via p21 and rictor

Cheung, C.; Patinote, A.; Guiguen, Y.; Bobe, J.

10.1101/294785 — developmental biology — Posted on 2018-04-04

1872 Single-cell analysis identifies EpCAM+/CDH6+/TROP-2- cells as human liver progenitors.

Segal, J. M.; Wesche, D. J.; Serra, M. P.; Oules, B.; Kent, D.; Ng, S. S.; Kar, G.; Emerton, G.; Blackford, S.; Darmanis, S.; Miquel, R.; Vinh, T.; Yamamoto, R.; Bonham, A.; Vigilante, A.; Teichmann, S.; Quake, S. R.; Nakauchi, H.; Rashid, S. T.

10.1101/294272 — cell biology — Posted on 2018-04-04

1873 Physics of lumen growth

Dasgupta, S.; Gupta, K.; Zhang, Y.; Viasnoff, V.; Prost, J.

10.1101/294264 — biophysics — Posted on 2018-04-04

1874 A scalable estimator of SNP heritability for Biobank-scale data

Wu, Y.; Sankararaman, S.

10.1101/294470 — bioinformatics — Posted on 2018-04-04

1875 Accurate prediction of orthologs in the presence of divergence after duplication

Lafond, M.; Meghdari Miardan, M.; Sankoff, D.

10.1101/294405 — bioinformatics — Posted on 2018-04-04

1876 Colonization of phosphate-solubilizing Pseudomonas sp. strain P34-L in the wheat rhizosphere and its effects on wheat growth and the expression of phosphate transporter gene TaPT4 in wheat

Liu, X.; Jiang, X.; Zhao, W.; Cao, Y.; Guo, T.; He, X.; Ni, H.; Tang, X.

10.1101/294736 — microbiology — Posted on 2018-04-04

1877 Maintenance of Cell Fates by Regulation of the Histone Variant H3.3 in Caenorhabditis elegans

Shibata, Y.; Nishiwaki, K.

10.1101/294827 — developmental biology — Posted on 2018-04-04

1878 GET_PHYLOMARKERS, a software package to select optimal orthologous clusters for phylogenomics and inferring pan-genome phylogenies, used for a critical geno-taxonomic revision of the genus Stenotrophomonas

Vinuesa, P.; Ochoa-Sanchez, L. E.; Contreras-Moreira, B.

10.1101/294660 — genomics — Posted on 2018-04-04

1879 Adult Plant Resistance in Maize to Northern Leaf Spot Is a Feature of Partial Loss-of-function Alleles of Hm1

Marla, S. R.; Chu, K.; Chintamanani, S.; Multani, D. S.; Klempien, A.; DeLeon, A.; Bong-suk, K.; Dunkle, L. D.; Dilkes, B. P.; Johal, G. S.

10.1101/244491 — pathology — Posted on 2018-04-04

1880 Robo1 and 2 repellent receptors cooperate to guide facial neuron cell migration and axon projections in the embryonic mouse hindbrain

Gruner, H. N.; Kim, M.; Mastick, G. S.

10.1101/294702 — neuroscience — Posted on 2018-04-04

1881 metamicrobiomeR: an R package for analysis of microbiome relative abundance data using zero-inflated beta GAMLSS and meta-analysis across studies using random effect models

Ho, N. T.; Li, F.

10.1101/294678 — bioinformatics — Posted on 2018-04-04

1882 UNC-6/Netrin and its Receptors UNC-5 and UNC-40/DCC Control Growth Cone Polarity, Microtubule Accumulation, and Protrusion

Gujar, M. R.; Sundararajan, L.; Stricker, A. M.; Lundquist, E. A.

10.1101/294215 — neuroscience — Posted on 2018-04-03

1883 The expression of class II major histocompatibility molecules on breast tumors delays T cell exhaustion, expands the T cell repertoire and slows tumor growth

McCaw, T.; Li, M.; Starenki, D.; Cooper, S.; Meza-Perez, S.; Arend, R.; LoBuglio, A.; Buchsbaum, D.; Forero, A.; Randall, T.

10.1101/294124 — immunology — Posted on 2018-04-03

1884 Characterisation of subpopulations of chicken mononuclear phagocytes that express TIM4 and the macrophage colony-stimulating factor receptor (CSF1R)

Hu, T.-j.; wu, Z.; Bush, S. J.; Freem, L.; Vervelde, L.; Summers, K. M.; Balic, A.; Hume, D. A.; Kaiser, P.

10.1101/294504 — immunology — Posted on 2018-04-03

1885 Visualizing conformational dynamics of proteins in solution and at the cell membrane

Gordon, S. E.; Munari, M.; Zagotta, W. N.

10.1101/294538 — biochemistry — Posted on 2018-04-03

1886 An evolutionary transcriptomics approach links CD36 to membrane remodeling in replicative senescence

Saitou, M.; Lizardo, D.; Taskent, R.; Millner, A.; Atilla-Gokcumen, G. E.; Gokcumen, O.

10.1101/294512 — cell biology — Posted on 2018-04-03

1887 The AP-1 complex is essential for fungal growth via its role in secretory vesicle polar sorting, endosomal recycling and cytoskeleton organization

Martzoukou, O.; Diallinas, G.; Amillis, S.

10.1101/294223 — cell biology — Posted on 2018-04-03

1888 Spatial organization of projection neurons in the mouse auditory cortex identified by in situ barcode sequencing

Chen, X.; Kebschull, J. M.; Zhan, H.; Sun, Y.-C.; Zador, A. M.

10.1101/294637 — neuroscience — Posted on 2018-04-03

1889 Microbial diversity and metabolic potential in cyanotoxin producing cyanobacterial mats throughout a river network

Bouma-Gregson, K.; Olm, M. R.; Probst, A. J.; Anantharaman, K.; Power, M. E.; Banfield, J. F.

10.1101/294421 — microbiology — Posted on 2018-04-03

1890 Electrophysiological evidence for cerebellar involvement in higher-order cognitive processing

Sendhilnathan, N.; Semework, M.; Goldberg, M. E.; Ipata, A. E.

10.1101/294454 — neuroscience — Posted on 2018-04-03

1891 An ultralight head-mounted camera system integrates detailed behavioral monitoring with multichannel electrophysiology in freely moving mice

Meyer, A. F.; Poort, J.; O'Keefe, J.; Sahani, M.; Linden, J. F.

10.1101/294397 — neuroscience — Posted on 2018-04-03

1892 Fitness effects of altering gene expression noise in Saccharomyces cerevisiae

Duveau, F.; Hodgins-Davis, A.; Metzger, B. P. H.; Yang, B.; Tryban, S.; Walker, E. A.; Lybrook, P.; Wittkopp, P. J.

10.1101/294603 — evolutionary biology — Posted on 2018-04-03

1893 Piezo1 calcium flickers localize to hotspots of cellular traction forces

Ellefsen, K.; Chang, A.; Nourse, J. L.; Holt, J. R.; Arulmoli, J.; Mekhdjian, A.; Flanagan, L. A.; Dunn, A. R.; Parker, I.; Pathak, M. M.

10.1101/294611 — biophysics — Posted on 2018-04-03

1894 PinMol: Python application for designing molecular beacons for live cell imaging of endogenous mRNAs

Bayer, L. V.; Omar, O. S.; Bratu, D. P.; Catrina, I. E.

10.1101/294447 — molecular biology — Posted on 2018-04-03

1895 Dynamics of Plasma Lipidome in Progression to Islet Autoimmunity and Type 1 Diabetes: Type 1 Diabetes Prediction and Prevention Study (DIPP)

Lamichhane, S.; Ahonen, L.; Dyrlund, T. S.; Kemppainen, E.; Siljander, H.; Hyoty, H.; Ilonen, J.; Toppari, J.; Veijola, R.; Hyotylainen, T.; Knip, M.; Oresic, M.

10.1101/294033 — biochemistry — Posted on 2018-04-03

1896 Primate immunodeficiency virus Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex

Yurkovetskiy, L.; Guney, M. H.; Kim, K.; Goh, S. L.; McCauley, S. M.; Dauphin, A.; Diehl, W. E.; Luban, J.

10.1101/293001 — molecular biology — Posted on 2018-04-03

1897 Enabling Precision Medicine via standard communication of NGS provenance, analysis, and results

Alterovitz, G.; Dean, D. A.; Goble, C.; Crusoe, M. R.; Soiland-Reyes, S.; Bell, A.; Hayes, A.; Suresh, A.; King, C. H. S.; Taylor, D.; Addepalli, K.; Johanson, E.; Thompson, E. E.; Donaldson, E.; Morizono, H.; Tsang, H.; Vora, J. K.; Goecks, J.; Yao, J.; Almeida, J. S.; Krampis, K.; Smith, K.; Guo, L.; Walderhaug, M.; Schito, M.; Ezewudo, M.; Guimera, N.; Walsh, P.; Kahsay, R.; Gottipati, S.; Rodwell, T. C.; Bloom, T.; Lai, Y.; Simonyan, V.; Mazumder, R.

10.1101/191783 — scientific communication and education — Posted on 2018-04-03

1898 A decisional space account of saccadic reaction times towards personally familiar faces

Ramon, M.; Sokhn, N.; Caldara, R.

10.1101/292656 — animal behavior and cognition — Posted on 2018-04-03

1899 A distributed neural code in ensembles of dentate gyrus granule cells

Stefanini, F.; Kheirbek, M.; Kushnir, L.; Jennings, J. H.; Stuber, G.; Hen, R.; Fusi, S.

10.1101/292953 — neuroscience — Posted on 2018-04-03

1900 Differential carbohydrate utilization and organic acid production by honey bee symbionts

Lee, F. J.; Miller, K. I.; McKinlay, J. B.; Newton, I. L. G.

10.1101/294249 — microbiology — Posted on 2018-04-03

1901 Modulation of antibiotic sensitivity and biofilm formation in Pseudomonas aeruginosa by interspecies diffusible signal factor analogues

An, S.-q.; Murtagh, J.; Twomey, K. B.; Gupta, M. K.; O'Sullivan, T. P.; Ingram, R.; Valvano, M. A.; Tang, J.-l.

10.1101/291260 — microbiology — Posted on 2018-04-03

1902 The quantification of protein-protein interaction interfaces using solvent-excluded surface-defined properties

Wang, L.

10.1101/294074 — bioinformatics — Posted on 2018-04-03

1903 Candidate Gene Networks for Acylsugar Metabolism and Plant Defense in Wild Tomato Solanum pennellii

Mandal, S.; Ji, W.; McKnight, T.

10.1101/294306 — plant biology — Posted on 2018-04-03

1904 Inheritance of neural substrates for motivation and pleasure experience

Li, Z.; Wang, Y.; Yan, C.; Li, K.; Zeng, Y.-w.; Cheung, E. F. C.; Docherty, A. R.; Sham, P. C.; Gur, R. E.; Gur, R. C.; Chan, R. C. K.

10.1101/294090 — neuroscience — Posted on 2018-04-03

1905 Increased speech representation in older adults originates from early response in higher order auditory cortex

Brodbeck, C.; Presacco, A.; Anderson, S.; Simon, J. Z.

10.1101/294017 — neuroscience — Posted on 2018-04-03

1906 HIV-1 specifically traps and depletes CD9 and CD81 tetraspanins during egress

Dahmane, S.; Doucet, C.; Le Gall, A.; Chamontin, C.; Dosset, P.; Murcy, F.; Fernandez, L.; Salas Pastene, D.; Rubinstein, E.; Mougel, M.; Nollmann, M.; Milhiet, P.-E.

10.1101/293860 — microbiology — Posted on 2018-04-03

1907 BROCKMAN: Deciphering variance in epigenomic regulators by k-mer factorization

de Boer, C.; Regev, A.

10.1101/129247 — genomics — Posted on 2018-04-03

1908 Loss of E2F7 confers resistance to poly-ADP-ribose polymerase (PARP) inhibitors in BRCA2-deficient cells

Clements, K. E.; Thakar, T.; Nicolae, C. M.; Liang, X.; Wang, H.-G.; Moldovan, G.-L.

10.1101/294371 — cancer biology — Posted on 2018-04-03

1909 A Stochastic Model for Cancer Metastasis: Branching Stochastic Process with Settlement

Frei, C.; Hillen, T.; Rhodes, A.

10.1101/294157 — cancer biology — Posted on 2018-04-03

1910 PDX Finder: A Portal for Patient-Derived tumor Xenograft Model Discovery

Conte, N.; Mason, J.; Halmagyi, C.; Neuhauser, S.; Mosaku, A.; Begley, D. A.; Kupkre, D. M.; Parkinson, H.; Meehan, T.; Bult, C. J.

10.1101/291443 — cancer biology — Posted on 2018-04-03

1911 Liquid-Liquid Phase Separation of Patchy Particles Illuminates Diverse Effects of Regulatory Components on Protein Droplet Formation

Nguemaha, V.; Zhou, H.-X.

10.1101/294058 — biophysics — Posted on 2018-04-03

1912 Stability of local secondary structure determines selectivity of viral RNA chaperones

Bravo, J. P. K.; Borodavka, A.; Barth, A.; Calabrese, A. N.; Mojzes, P.; Cockburn, J. J. B.; Lamb, D. C.; Tuma, R.

10.1101/293191 — biophysics — Posted on 2018-04-03

1913 Single-particle tracking of Nucleotide Excision Repair proteins inside living bacteria

Piotrowska, A.; Stracy, M.; Zawadzki, P.

10.1101/293910 — biophysics — Posted on 2018-04-03

1914 iTOP: Inferring the Topology of Omics Data

Aben, N.; Westerhuis, J. A.; Song, Y.; Kiers, H. A. L.; Michaut, M.; Smilde, A. K.; Wessels, L. F. A.

10.1101/293993 — bioinformatics — Posted on 2018-04-03

1915 Epigenetic prediction of complex traits and death

McCartney, D. L.; Stevenson, A. J.; Ritchie, S. J.; Walker, R. M.; Zhang, Q.; Morris, S. W.; Campbell, A.; Murray, A. D.; Whalley, H. C.; Gale, C. R.; Porteous, D. J.; Haley, C. S.; McRae, A. F.; Wray, N. R.; Visscher, P. M.; McIntosh, A. M.; Evans, K. L.; Deary, I. J.; Marioni, R. E.

10.1101/294116 — genomics — Posted on 2018-04-03

1916 Coarse-Grained Model of the SNARE Complex Shows that Quick Zippering Requires Partial Assembly

Fortoul, N.; Bykhovskaia, M.; Jagota, A.

10.1101/294181 — biophysics — Posted on 2018-04-03

1917 Cancer subtype identification using somatic mutation data

Kuijjer, M. L.; Paulson, J. N.; Salzman, P.; Ding, W.; Quackenbush, J.

10.1101/228031 — genomics — Posted on 2018-04-03

1918 Movement imitation depends on an abstract trajectory representation in dorsal premotor cortex

Wong, A. L.; Jax, S. A.; Smith, L. L.; Buxbaum, L. J.; Krakauer, J. W.

10.1101/294207 — neuroscience — Posted on 2018-04-03

1919 The drivers and consequences of unstable Plasmodium dynamics: A long-term study of three malaria parasite species infecting a tropical lizard

Otero, L.; Schall, J. J.; Cruz, V.; Aaltonen, K.; Acevedo, M.

10.1101/189696 — ecology — Posted on 2018-04-03

1920 Subject-specificity of the correlation between large-scale structural and functional connectivity

Zimmermann, J.; Griffiths, J.; Schirner, M.; Ritter, P.; McIntosh, A. R.

10.1101/277590 — neuroscience — Posted on 2018-04-03

1921 Cochaperones enable Hsp70 to fold proteins like a Maxwell’s demon

Xu, H.

10.1101/283143 — biophysics — Posted on 2018-04-03

1922 Example of Methylome Analysis with MethylIT using Cancer Datasets

Sanchez, R.; Mackenzie, S.

10.1101/261982 — bioinformatics — Posted on 2018-04-03

1923 Synonymous lysine codon usage modification in a mobile antibiotic resistance gene similarly alters protein production in bacterial species with divergent lysine codon usage biases because it removes a duplicate AAA lysine codon.

Alorabi, M.; AlAmri, A. M.; Takbayashi, Y.; Heesom, K. J.; Avison, M.

10.1101/294173 — microbiology — Posted on 2018-04-03

1924 Detection of GBA missense mutations and other variants using the Oxford Nanopore MinION

Leija-Salazar, M.; Sedlazeck, F. J.; Mokretar, K.; Mullin, S.; Toffoli, M.; Athanasopoulou, M.; Donald, A.; Sharma, R.; Hughes, D.; Schapira, A. H.; Proukakis, C.

10.1101/288068 — genetics — Posted on 2018-04-03

1925 Probabilistic Count Matrix Factorization for Single Cell Expression Data Analysis

Durif, G.; Modolo, L.; Mold, J. E.; Lambert-Lacroix, S.; Picard, F.

10.1101/211938 — bioinformatics — Posted on 2018-04-03

1926 Dental restoration longevity among geriatric and adult special needs patients

Caplan, D. J.; Li, Y.; Wang, W.; Kang, S.; Marchini, L.; Cowen, H.; Yan, J.

10.1101/202069 — bioengineering — Posted on 2018-04-03

1927 Genetic analysis using parent-progeny relationship for wood quality traits in Norway spruce (Picea abies (L.) Karst.)

Zhou, L.; Chen, Z.; Lundqvist, S.-O.; Olsson, L.; Grahn, T.; Karlsson, B.; Wu, H. X.; Garcia Gil, M. R.

10.1101/293969 — plant biology — Posted on 2018-04-03

1928 Movement imitation depends on an abstract trajectory representation in dorsal premotor cortex

Wong, A. L.; Jax, S. A.; Smith, L. A.; Buxbaum, L. J.; Krakauer, J. W.

10.1101/294207 — neuroscience — Posted on 2018-04-03

1929 Neuronal population mechanisms of lightness perception

Ruff, D.; Brainard, D. H.; Cohen, M. R.

10.1101/294280 — neuroscience — Posted on 2018-04-03

1930 Spotlight on islands: on the origin and diversification of a new lineage of the Italian wall lizard Podarcis siculus in the western Pontine Islands

Senczuk, G.; Havenstein, K.; Milana, V.; Ripa, C.; De Simone, E.; Tiedemann, R.; Castiglia, R.

10.1101/293985 — evolutionary biology — Posted on 2018-04-03

1931 The dynamics of preferential host switching: host phylogeny as a key predictor of parasite prevalence and distribution

Engelstaedter, J.; Fortuna, N. Z.

10.1101/209254 — evolutionary biology — Posted on 2018-04-03

1932 A non-cell autonomous actin redistribution enables isotropic retinal growth

Matejcic, M.; Salbreux, G.; Norden, C.

10.1101/293951 — developmental biology — Posted on 2018-04-03

1933 Dimer arrangement and monomer flattening determine actin filament formation

Hoyer, M.; Cabral Correia, J. R.; Lamb, D. C.; Crevenna, A. H.

10.1101/294256 — biophysics — Posted on 2018-04-03

1934 Haplotype-aware genotyping from noisy long reads

Ebler, J.; Haukness, M.; Pesout, T.; Marschall, T.; Paten, B.

10.1101/293944 — bioinformatics — Posted on 2018-04-03

1935 An accurate and robust algorithm for solvent-excluded surface computation

Wang, L.

10.1101/294025 — bioinformatics — Posted on 2018-04-03

1936 LIkelihood-based Fits of Folding Transitions (LIFFT) for Biomolecule Mapping Data

Das, R.

10.1101/294041 — biochemistry — Posted on 2018-04-03

1937 Estimating correlated rates of trait evolution with uncertainty

Caetano, D. S.; Harmon, L. J.

10.1101/102939 — evolutionary biology — Posted on 2018-04-03

1938 KrakenHLL: Confident and fast metagenomics classification using unique k-mer counts

Breitwieser, F. P.; Salzberg, S. L.

10.1101/262956 — bioinformatics — Posted on 2018-04-03

1939 Elucidating synergistic dependencies in lung adenocarcinoma by proteome-wide signaling-network analysis

Bansal, M.; He, J.; Peyton, M.; Kaustagi, M.; Iyer, A.; Comb, M.; White, M.; Minna, J.; Califano, A.

10.1101/289603 — systems biology — Posted on 2018-04-03

1940 Influence of learning strategy on response time during complex value-based learning and choice

Farashahi, S.; Rowe, K.; Aslami, Z.; Gobbini, M. I.; Soltani, A.

10.1101/248336 — neuroscience — Posted on 2018-04-03

1941 Estimating the proportion of bystander selection for antibiotic resistance in the US

Tedijanto, C.; Olesen, S.; Grad, Y.; Lipsitch, M.

10.1101/288704 — epidemiology — Posted on 2018-04-03

1942 Gene inversion increases evolvability in bacteria

Merrikh, C. N.; Merrikh, H.

10.1101/293571 — evolutionary biology — Posted on 2018-04-03

1943 T-cell receptor αβ chain pairing is associated with CD4+ and CD8+ lineage specification

Carter, J. A.; Preall, J. B.; Grigaityte, K.; Goldfless, S. J.; Briggs, A. W.; Vigneault, F.; Atwal, G. S.

10.1101/293852 — immunology — Posted on 2018-04-03

1944 Thought Control Failure: Sensory Determinants and Functional Effects

Kwok, E. L.; Leys, G.; Koenig-Robert, R.; Pearson, J.

10.1101/293761 — neuroscience — Posted on 2018-04-03

1945 Hypoxia increases the tempo of evolution in the peri-necrotic niche in glioblastoma

Grimes, D. R.; Macauley, R. J.; Currell, F.; Scott, J.; Basanta, D.

10.1101/293712 — cancer biology — Posted on 2018-04-03

1946 Mice follow odor trials using stereo olfactory cues and rapid sniff to sniff comparisons

Jones, P. W.; Urban, N. N.

10.1101/293746 — animal behavior and cognition — Posted on 2018-04-03

1947 Integrated systems biology and imaging of the smallest free-living eukaryote Ostreococcus tauri

Smallwood, C. R.; Chen, J.-H.; Kumar, N.; Chrisler, W.; Purvine, S. O.; Kyle, J. E.; Nicora, C. D.; Boudreau, R.; Ekman, A.; Hixson, K. K.; Moore, R. J.; McDermott, G.; Cannon, W. R.; Evans, J. E.

10.1101/293704 — systems biology — Posted on 2018-04-03

1948 Reactivation of latent HIV-1 in vitro using an alcoholic extract from Euphorbia umbellata (Euphorbiaceae) latex.

Valadao, A. L.; Pezzuto, P.; Silva, V. A. O.; Goncalves, B. S.; Rossi, A. D.; Delvecchio, R.; Siani, A. C.; Tostes, J. B. d. F.; Trovo, M.; Damasco, P.; Goncalves, G.; Reis, R. M.; Santana, R.; Bento, C. A. d. M.; Tanuri, A.

10.1101/293662 — microbiology — Posted on 2018-04-03

1949 Accuracy of genomic selection for growth and wood quality traits in two control-pollinated progeny trials using exome capture as genotyping platform in Norway spruce

Chen, Z.-q.; Baison, J.; Pan, J.; Karlsson, B.; Andersson, B. G.; Westin, J.; Garcia Gil, M. R.; Wu, H. X.

10.1101/293696 — genetics — Posted on 2018-04-03

1950 Structural basis for substrate binding and specificity of a sodium/alanine symporter AgcS

Ma, j.; Lei, H.-T.; Reyes, F. E.; Sanchez-Martinez, S.; Sarhan, M.; Gonen, T.

10.1101/293811 — biochemistry — Posted on 2018-04-03

1951 Cell cycle-controlled clearance of the CcrM DNA methyltransferase by Lon is dependent on DNA-facilitated proteolysis and substrate polar sequestration

Zhou, X.; Shapiro, L.

10.1101/293738 — molecular biology — Posted on 2018-04-03

1952 Minimizing Structural Bias in Single-Molecule Super-Resolution Microscopy

Mazidi, H.; Lu, J.; Nehorai, A.; Lew, M. D.

10.1101/293670 — bioinformatics — Posted on 2018-04-03

1953 Deep Convolutional Neural Networks for Breast Cancer Histology Image Analysis

Rakhlin, A.; Shvets, A.; Iglovikov, V.; Kalinin, A.

10.1101/259911 — pathology — Posted on 2018-04-02

1954 Estimating the proportion of bystander selection for antibiotic resistance in the US

Tedijanto, C.; Olesen, S.; Grad, Y.; Lipsitch, M.

10.1101/288704 — epidemiology — Posted on 2018-04-02

1955 Stability Criteria for Complex Microbial Communities

Butler, S.; O'Dwyer, J.

10.1101/293605 — ecology — Posted on 2018-04-02

1956 Structures of DPAGT1 explain glycosylation disease mechanisms and advance TB antibiotic design

Dong, Y. Y.; Wang, H.; Pike, A. C.; Cochrane, S. J.; Hamedzade, S.; Wyszynsk, F. J.; Bushell, S. R.; Royer, S. F.; Widdick, D. A.; Sajid, A.; Boshoff, H. I.; Lucas, R.; Liu, W.-M.; Lee, S. S.; Machida, T.; Mehmood, S.; Liu, W.-W.; Belaya, K.; Chu, A.; Shrestha, L.; Mukhopadhyay, S.; Burgess-Brown, N. A.; Bibb, M. J.; Barry, C. E.; Robinson, C. V.; Beeson, D.; Davis, B. G.; Carpenter, E. P.

10.1101/291278 — biochemistry — Posted on 2018-04-02

1957 Distinct sequence patterns in the active postmortem transcriptome

Noble, P. A.; Pozhitkov, A. E.

10.1101/293589 — systems biology — Posted on 2018-04-02

1958 Identifying neural predictors of response to cortical or striatal deep brain stimulation in a rodent model of alcohol drinking: Towards developing individualized therapies for alcohol use disorders

Henricks, A. M.; Dwiel, L. L.; Deveau, N. H.; Simon, A. A.; Green, A. I.; Doucette, W. T.

10.1101/293597 — neuroscience — Posted on 2018-04-02

1959 Estimating the frequency of multiplets in single-cell RNA sequencing from cell-mixing experiments

Bloom, J. D.

10.1101/293639 — genomics — Posted on 2018-04-02

1960 Assembly-free and alignment-free sample identification using genome skims

Sarmashghi, S.; Bohmann, K.; Gilbert, M. T. P.; Bafna, V.; Mirarab, S.

10.1101/230409 — ecology — Posted on 2018-04-02

1961 CD95 receptor activation by ligand-induced trimerization is independent of its partial pre-ligand assembly

Liesche, C.; Berndt, J.; Fricke, F.; Aschenbrenner, S.; Heilemann, M.; Eils, R.; Beaudouin, J.

10.1101/293530 — cell biology — Posted on 2018-04-02

1962 A Nested 2-Level Cross-validation Ensemble Learning Pipeline Suggests a Negative Pressure Against Crosstalk snoRNA-mRNA Interactions in Saccharomyces cerevisae

Soule, A.; Steyaert, J.-M.; Waldispuhl, J.

10.1101/293555 — bioinformatics — Posted on 2018-04-02

1963 On the deformability of an empirical fitness landscape by microbial evolution

Bajic, D.; Vila, J. C. C.; Blount, Z. D.; Sanchez, A.

10.1101/293407 — evolutionary biology — Posted on 2018-04-02

1964 Gene inversion increases evolvability in bacteria

Merrikh, H.; Merrikh, C. N.

10.1101/293571 — evolutionary biology — Posted on 2018-04-02

1965 Forecasting Future Humphrey Visual Fields Using Deep Learning

Wen, J. C.; Lee, C. S.; Keane, P. A.; Xiao, S.; Wu, Y.; Rokem, A.; Chen, P. P.; Lee, A. Y.

10.1101/293621 — bioinformatics — Posted on 2018-04-02

1966 Deep sequencing analysis of CRISPR-escaping plasmid transconjugants in Enterococcus faecalis

Huo, W.; Price, V. J.; Sharifi, A.; Zhang, M. Q.; Palmer, K. L.

10.1101/220467 — microbiology — Posted on 2018-04-02

1967 Enter the matrix: factorization uncovers knowledge from omics

Stein-O'Brien, G. L.; Arora, R.; Culhane, A. C.; Favorov, A.; Garmire, L. X.; Greene, C.; Goff, L. A.; Li, Y.; Ngom, A.; Ochs, M. F.; Xu, Y.; Fertig, E. J.

10.1101/196915 — systems biology — Posted on 2018-04-02

1968 Single-cell Map of Diverse Immune Phenotypes Driven by the Tumor Microenvironment

Azizi, E.; Carr, A. J.; Plitas, G.; Cornish, A. E.; Konopacki, C.; Prabhakaran, S.; Nainys, J.; Wu, K.; Kiseliovas, V.; Setty, M.; Choi, K.; Fromme, R. M.; Dao, P.; McKenney, P. T.; Wasti, R. C.; Kadaveru, K.; Mazutis, L.; Rudensky, A. Y.; Pe'er, D.

10.1101/221994 — immunology — Posted on 2018-04-02

1969 Deletion of the Creatine Transporter in dopaminergic neurons leads to hyperactivity in mice.

Abdulla, Z. I.; Pahlevani, B.; Pennington, J. L.; Latushka, N.; Skelton, M.

10.1101/293563 — neuroscience — Posted on 2018-04-02

1970 Astroplastic: A start-to-finish process for polyhydroxybutyrate production from solid human waste using genetically engineered bacteria to address the challenges for future manned Mars missions

Chen, X.; Ibrahim, S.; Kunitskaya, A.; Schaaf, K.; Wang, Z. F.; Gopalakrishan, P.; Noor, M.; Wilton-Clark, H.; Grainger, J.; Ivanova, A.; Lim, P.; Olsakova, M.; Bharadwaj, L.; Sher, B.; Feehan, D.; Varga, R.; Arcellana-Panlilio, M.

10.1101/288746 — synthetic biology — Posted on 2018-04-02

1971 Animal models of chemotherapy-induced peripheral neuropathy: a machine-assisted systematic review and meta-analysis A comprehensive summary of the field to inform robust experimental design

Currie, G. L.; Angel-Scott, H.; Colvin, L.; Cramond, F.; Hair, K.; Khandoker, L.; Liao, J.; Macleod, M. R.; McCann, S. K.; Morland, R.; Sherratt, N.; Stewart, R.; Tanriver-Ayder, E.; Thomas, J.; Wang, Q.; Wodarski, R.; Xiong, R.; Rice, A. S. C.; Sena, E. S.

10.1101/293480 — neuroscience — Posted on 2018-04-02

1972 Hippocampal Pattern Separation Supports Reinforcement Learning

Ballard, I. C.; Wagner, A. D.; McClure, S. M.

10.1101/293332 — neuroscience — Posted on 2018-04-02

1973 A continental system for forecasting bird migration

Van Doren, B. M.; Horton, K. G.

10.1101/293092 — ecology — Posted on 2018-04-02

1974 Efficient inverse graphics in biological face processing

Yildirim, I.; Freiwald, W.; Tenenbaum, J.

10.1101/282798 — neuroscience — Posted on 2018-04-02

1975 Gamma synchronization between V1 and V4 improves behavioral performance

Rohenkohl, G.; Bosman, C. A.; Fries, P.

10.1101/290817 — neuroscience — Posted on 2018-04-02

1976 Sparse recurrent excitatory connectivity in the cortical microcircuit of the adult mouse and human

10.1101/292706 — neuroscience — Posted on 2018-04-02

1977 Phrank measures phenotype sets similarity to greatly improve Mendelian diagnostic disease prioritization

Jagadeesh, K.; Birgmeier, J.; Guturu, H.; Deisseroth, C. A.; Wenger, A. M.; Bernstein, J. A.; Bejerano, G.

10.1101/225854 — genomics — Posted on 2018-04-02

1978 Plant odour and sex pheromone are integral elements of specific mate recognition in an insect herbivore

Borrero-Echeverry, F.; Bengtsson, M.; Witzgall, P.

10.1101/293100 — evolutionary biology — Posted on 2018-04-02

1979 Deletion of genes encoding PU.1 and Spi-B leads to B cell acute lymphoblastic leukemia associated with driver mutations in Janus Kinases

Batista, C. R.; Lim, M.; Laramee, A.-S.; Abu-Sardanah, F.; Xu, L. S.; Hossain, R.; DeKoter, R. P.

10.1101/291054 — cancer biology — Posted on 2018-04-02

1980 Geometry-dependent instabilities in electrically excitable tissues

McNamara, H. M.; Dodson, S.; Huang, Y.-L.; Miller, E. W.; Sandstede, B.; Cohen, A. E.

10.1101/291617 — biophysics — Posted on 2018-04-02

1981 The CoLoMoTo Interactive Notebook: Accessible and Reproducible Computational Analyses for Qualitative Biological Networks

Naldi, A.; Hernandez, C.; Levy, N.; Stoll, G.; Monteiro, P. T.; Chaouiya, C.; Helikar, T.; Zinovyev, A.; Calzone, L.; Cohen-Boulakia, S.; Thieffry, D.; Pauleve, L.

10.1101/290411 — bioinformatics — Posted on 2018-04-02

1982 P. falciparum PfATP4 Multi-Drug Resistance to KAE609 (Cipargamin) is Present in Africa

McCulloch, J.

10.1101/293035 — bioinformatics — Posted on 2018-04-02

1983 Integrative analysis of pharmacogenomics in major cancer cell line databases using CellMinerCDB

Rajapakse, V. N.; Luna, A.; Yamade, M.; Loman, L.; Varma, S.; Sunshine, M.; Iorio, F.; Sousa, F. G.; Elloumi, F.; Aladjem, M. I.; Thomas, A.; Sander, C.; Kohn, K.; Benes, C. H.; Garnett, M.; Reinhold, W. C.; Pommier, Y.

10.1101/292904 — bioinformatics — Posted on 2018-04-02

1984 Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in amphibians and mammals

Opazo, J. C.; Zavala, K.

10.1101/293522 — evolutionary biology — Posted on 2018-04-02

1985 A conserved Lkb1 signaling axis modulates TORC2 signaling in budding yeast

Alcaide Gavilan, M.; Lucena, R.; Schubert, K.; Artiles, K.; Zapata, J.; Kellogg, D.

10.1101/293209 — cell biology — Posted on 2018-04-02

1986 Orthogonal fingerprinting for accurate and fast single-molecule mechanical profiling of proteins

Pimenta-Lopes, C.; Suay-Corredera, C.; Velazquez-Carreras, D.; Sanchez-Ortiz, D.; Alegre-Cebollada, J.

10.1101/293506 — biophysics — Posted on 2018-04-02

1987 Deep Learning Global Glomerulosclerosis in Transplant Kidney Frozen Sections

Marsh, J. N.; Matlock, M. K.; Kudose, S.; Liu, T.-C.; Stappenbeck, T. S.; Gaut, J. P.; Swamidass, S. J.

10.1101/292789 — bioinformatics — Posted on 2018-04-02

1988 Systemically administered MSCs given 24hrs after osteotomy do not affect bone formation in rat distraction osteogenesis

Guevara, J.; Toth, Z.; Kim, D.; Peters, J.; Marley-Weaver, A.; Watson, T.; McBride-Gagyi, S.

10.1101/293514 — bioengineering — Posted on 2018-04-02

1989 Multimodal Hippocampal Subfield Grading For Alzheimer’s Disease Classification

Hett, K.; Ta, V. T.; Catheline, G.; Tourdias, T.; Manjon, J.; Coupe, P.

10.1101/293126 — neuroscience — Posted on 2018-04-02

1990 Tissue dependent expression of bitter receptor TAS2R38 mRNA

Douglas, J. E.; Lin, C.; Mansfield, C. J.; Arayata, C. J.; Cowart, B. J.; Spielman, A. I.; Adappa, N. D.; Palmer, J. N.; Reed, D. R.; Cohen, N. A.

10.1101/293399 — molecular biology — Posted on 2018-04-02

1991 Consumption of carotenoids not increased by bacterial infection in brown trout embryos (Salmo trutta)

Marques da Cunha, L.; Wilkins, L. G. E.; Menin, L.; Ortiz, D.; Vocat-Mottier, V.; Wedekind, C.

10.1101/293142 — ecology — Posted on 2018-04-02

1992 Weakly supervised learning of single-cell feature embeddings

Caicedo, J. C.; McQuin, C.; Goodman, A.; Singh, S.; Carpenter, A. E.

10.1101/293431 — bioinformatics — Posted on 2018-04-02

1993 Using citizen science data in integrated population models to inform conservation decision-making

Robinson, O. J.; Ruiz-Gutierrez, V.; Fink, D.; Meese, R. J.; Holyoak, M.; Cooch, E. G.

10.1101/293464 — ecology — Posted on 2018-04-02

1994 Predicting resistance of clinical Abl mutations to targeted kinase inhibitors using alchemical free-energy calculations

Hauser, K.; Negron, C.; Albanese, S. K.; Ray, S.; Steinbrecher, T.; Abel, R.; Chodera, J. D.; Wang, L.

10.1101/239012 — cancer biology — Posted on 2018-04-02

1995 ELMER v.2: An R/Bioconductor package to reconstruct gene regulatory networks from DNA methylation and transcriptome profiles

Chedraoui Silva, T.; Coetzee, S. G.; Yao, L.; Gull, N.; Hazelett, D. J.; Noushmehr, H.; Lin, D.-C.; Berman, B. P.

10.1101/148726 — bioinformatics — Posted on 2018-04-02

1996 Electrical stimulation in hippocampus and entorhinal cortex impairs spatial and temporal memory

Goyal, A.; Miller, J.; Watrous, A. J.; Lee, S. A.; Coffey, T.; Sperling, M.; Sharan, A.; Worrell, G.; Brent, B.; Lega, B.; Jobst, B. C.; Davis, K.; Inman, C.; Sheth, S.; Wanda, P. A.; Ezzyat, Y.; Das, S.; Stein, J.; Gorniak, R.; Jacobs, J.

10.1101/215806 — neuroscience — Posted on 2018-04-02

1997 Global connectivity of the frontoparietal cognitive control network is related to depression symptoms in the general population

Schultz, D. H.; Ito, T.; Solomyak, L. I.; Chen, R. H.; Mill, R. D.; Anticevic, A.; Cole, M. W.

10.1101/185306 — neuroscience — Posted on 2018-04-02

1998 Antibody-based vaccine for tuberculosis: validation in horse foals challenged with the TB-related pathogen Rhodococcus equi

Cywes-Bentley, C.; Rocha, J. N.; Bordin, A. I.; Vinacur, M.; Rehman, S.; Zaidi, T. S.; Meyer, M.; Anthony, S.; Lambert, M.; Vlock, D. R.; Giguere, S.; Cohen, N. D.; Pier, G. B.

10.1101/292946 — immunology — Posted on 2018-04-02

1999 Constant conflict between Gypsy LTR retrotransposons and CHH methylation within a stress-adapted mangrove genome

Wang, Y.; Liang, W.; Tang, T.

10.1101/263830 — evolutionary biology — Posted on 2018-04-02

2000 Sequential regulation of maternal mRNAs through a conserved cis-acting element in their 3’UTRs

Flora, P.; Wong-Deyrup, S. W.; Martin, E.; Palumbo, R.; Nasrallah, M.; Oligney, A.; Blatt, P.; Patel, D.; Fuchs, G.; Rangan, P.

10.1101/285569 — developmental biology — Posted on 2018-04-02

2001 Rainbow-seq: combining cell lineage tracking with single-cell RNA sequencing in preimplantation embryos

Biase, F.; Wu, Q.; Calandrelli, R.; Rivas-Astroza, M.; Zhou, S.; Zhong, S.

10.1101/293134 — developmental biology — Posted on 2018-04-02

2002 Development of a joint evolutionary model for the genome and the epigenome

Lu, J.; Cao, X.; Zhong, S.

10.1101/293076 — bioinformatics — Posted on 2018-04-02

2003 Accounting for programmed ribosomal frameshifting in the computation of codon usage bias indices

Garcia, V.; Anisimova, M.

10.1101/293340 — genetics — Posted on 2018-04-02

2004 Wnt/β-catenin regulates an ancient signaling network during zebrafish scale development

Aman, A. J.; Fulbright, A. N.; Parichy, D. M.

10.1101/293233 — developmental biology — Posted on 2018-04-02

2005 Velocity and Diameter Measurements of Penetrating Arteries by Model Based Analysis of Complex Difference Images in Phase Contrast MRI

Zong, X.; Lin, W.

10.1101/293308 — biophysics — Posted on 2018-04-02

2006 Fast and simple comparison of semi-structured data, with emphasis on electronic health records

Robinson, M.; Hadlock, J.; Yu, J.; Khatamian, A.; Aravkin, A. Y.; Deutsch, E. W.; Price, N. D.; Huang, S.; Glusman, G.

10.1101/293183 — bioinformatics — Posted on 2018-04-02

2007 TranCEP: Predicting transmembrane transport proteins using composition, evolutionary, and positional information

Alballa, M.; Aplop, F.; Butler, G.

10.1101/293159 — bioinformatics — Posted on 2018-04-02

2008 RobusTAD: A Tool for Robust Annotation ofTopologically Associating Domain Boundaries

Dali, R.; Bourque, G.; Blanchette, M.

10.1101/293175 — bioinformatics — Posted on 2018-04-02

2009 Collective feature selection to identify crucial epistatic variants

Verma, S. S.; Lucas, A. M.; Xhang, X.; Veturi, Y.; Dudek, S.; Li, B.; Li, R.; Urbanowicz, R.; Moore, J. H.; Kim, D.; Ritchie, M. D.

10.1101/293365 — bioinformatics — Posted on 2018-04-02

2010 Knockdown of GAS5 restores ox-LDL-induced impaired autophagy flux via upregulating miR-26a in human endothelial cells

Liang, W.; Fan, T.; Liu, L.; Zhang, L.

10.1101/293324 — biochemistry — Posted on 2018-04-02

2011 Scene complexity modulates degree of feedback activity during object recognition in natural scenes

Groen, I. I. A.; Jahfari, S.; Seijdel, N.; Ghebreab, S.; Lamme, V.; Scholte, H. S.

10.1101/293290 — neuroscience — Posted on 2018-04-02

2012 Differential regulation of the ZsGreen1 reporter gene by the human cytomegalovirus promoter in 35 tissues of neonatal transgenic swine.

Desaulniers, A. T.; Cederberg, R. A.; Carreiro, E. P.; Gurumurthy, C. B.; White, B. R.

10.1101/293258 — genomics — Posted on 2018-04-02

2013 Antibody-based vaccine for tuberculosis: validation in horse foals challenged with the TB-related pathogen Rhodococcus equi

Cywes-Bentley, C.; Rocha, J. N.; Bordin, A. I.; Vinacur, M.; Rehman, S.; Zaidi, T. S.; Meyer, M.; Anthony, S.; Lambert, M.; Vlock, D. R.; Giguere, S.; Cohen, N. D.; Pier, G. B.

10.1101/292946 — immunology — Posted on 2018-04-02

2014 Distributed Bayesian Networks Reconstruction on the Whole Genome Scale

Frolova, A.; Wilczynski, B.

10.1101/016683 — bioinformatics — Posted on 2018-04-02

2015 An ultra-dense haploid genetic map for evaluating the highly fragmented genome assembly of Norway spruce (Picea abies)

Bernhardsson, C.; Vidalis, A.; Wang, X.; Scofield, D. G.; Shiffthaler, B.; Baison, J.; Street, N. R.; Garcia Gil, M. R.; Ingvarsson, P. K.

10.1101/292151 — genetics — Posted on 2018-04-02

2016 Comparable affinity of RabGDIα for GTP- and GDP-bound forms of Rab7 supports a four-state transition model for Rab7 subcellular localization

Kanemitsu, A. F.; Morishita, S.; Kjaer, S.; Fukuda, M.; Schiavo, G.; Nakamura, T.

10.1101/287516 — cell biology — Posted on 2018-04-02

2017 Distinct Epigenomic Patterns Are Associated with Haploinsufficiency and Predict Risk Genes of Developmental Disorders

Han, X.; Chen, S.; Flynn, E. D.; Wu, S.; Wintner, D.; Shen, Y.

10.1101/205849 — genomics — Posted on 2018-04-02

2018 National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB): Outline and Patient-Matching Technique

Kubo, S.; Noda, T.; Myojin, T.; Nishioka, Y.; Higashino, T.; Matsui, H.; Kato, G.; Imamura, T.

10.1101/280008 — epidemiology — Posted on 2018-04-02

2019 MVP: predicting pathogenicity of missense variants by deep learning

Qi, H.; Chen, C.; Zhang, H.; Long, J. J.; Chung, W. K.; Guan, Y.; Shen, Y.

10.1101/259390 — bioinformatics — Posted on 2018-04-02

2020 On mechanisms of Transcranial Magnetic Stimulation (TMS): How brain state and baseline performance level determine behavioral effects of TMS

Silvanto, J.; Bona, S.; Marelli, M.; Cattaneo, Z.

10.1101/189969 — neuroscience — Posted on 2018-04-02

2021 Chronic exposure to a neonicotinoid pesticide and a synthetic pyrethroid in full-sized honey bee colonies

Odemer, R.; Rosenkranz, P.

10.1101/293167 — zoology — Posted on 2018-04-01

2022 Association mapping identified novel candidate loci affecting wood formation in Norway spruce

Baison, J.; Vidalis, A.; Zhou, L.; Chen, Z.-Q.; Li, Z.; Sillanpää, M. J.; Bernahrdsson, C.; Scofield, D. G.; Forsberg, N.; Olsson, L.; Karlsson, B.; Wu, H.; Ingvarsson, P. K.; Lundqvist, S.-O.; Niittylä, T.; Garcia Gil, R. M.

10.1101/292847 — genetics — Posted on 2018-04-01

2023 Cytokinin treatment of rice induces minimal effect on differential splicing compared to splicing between tissues

Freese, N.; Estrada, A. D.; Blakley, I. C.; Duan, J.; Loraine, A.

10.1101/293217 — molecular biology — Posted on 2018-04-01

2024 A conserved Lkb1 signaling axis modulates TORC2 signaling in budding yeast

Kellogg, D.; Lucena, R.; Alcaide-Gavilan, M.; Schubert, K.; Artiles, K.; Zapata, J.

10.1101/293209 — cell biology — Posted on 2018-04-01

2025 Co-expression of MDM2 and CDK4 in transformed human mesenchymal stem cells induces dedifferentiated liposarcoma potency

Kim, Y. J.; Sung, M.; Yu, D. B.; Kim, M.; Song, J.-Y.; Song, K.; Jung, K.; Choi, Y.

10.1101/293068 — cancer biology — Posted on 2018-04-01

2026 The cellular NMD pathway restricts Zika virus infection and is targeted by the viral capsid protein

Fontaine, K. A.; Leon, K. E.; Khalid, M. M.; Jimenez-Morales, D.; Dunlap, M.; Kaye, J. A.; Shah, P. S.; Finkbeiner, S.; Krogan, N. J.; Ott, M.

10.1101/290296 — microbiology — Posted on 2018-04-01

2027 Locality Sensitive Imputation for Single-Cell RNA-Seq Data

Moussa, M.; Mandoiu, I.

10.1101/291807 — bioinformatics — Posted on 2018-04-01

2028 A High-Throughput Pipeline Identifies Robust Connectomes But Troublesome Variability

10.1101/188706 — neuroscience — Posted on 2018-04-01

2029 Polygonal motion and adaptable phototaxis via flagellar beat switching in Euglena gracilis

Tsang, A. C. H.; Lam, A. T.; Riedel-Kruse, I. H.

10.1101/292896 — biophysics — Posted on 2018-04-01

2030 Widespread noncoded amino acids in human proteome

Yang, J.-H.; Chen, X.; Gong, J.; Zhao, H.; Li, C.; Bi, B.; Wang, F.; Sun, S.; Wang, X.; Lv, X.; Zhang, B.; Huang, T.; Azadzoi, K.; Shi, F.; Kong, X.; Shu, M.; Wang, Y.; Chin, Y. E.; Huang, W.; Chen, Z.; Chen, Z.-J.

10.1101/292474 — molecular biology — Posted on 2018-04-01

2031 Insect wings and body wall evolved from ancient leg segments

Bruce, H. S.; Patel, N. H.

10.1101/244541 — developmental biology — Posted on 2018-04-01

2032 Volvox barberi flocks, forming near-optimal, two-dimensional, polydisperse lattice packings

Balasubramanian, R.

10.1101/279059 — biophysics — Posted on 2018-04-01

2033 CODEX2: full-spectrum copy number variation detection by high-throughput DNA sequencing

Jiang, Y.; Wang, R.; Urrutia, E.; Anastopoulos, I. N.; Nathanson, K. L.; Zhang, N. R.

10.1101/211698 — bioinformatics — Posted on 2018-04-01

2034 Effects of anthropogenic wildfire activity in low elevation Pacific island vegetation communities in French Polynesia

Newman, E. A.; Winkler, C. A.; Hembry, D. H.

10.1101/196352 — ecology — Posted on 2018-04-01

2035 The scent of the fly

Becher, P. G.; Lebreton, S.; Wallin, E. A.; Hedenstrom, E.; Borrero-Echeverry, F.; Bengtsson, M.; Jorger, V.; Witzgall, P.

10.1101/206375 — animal behavior and cognition — Posted on 2018-04-01

2036 Pseudomonas aeruginosa type IV minor pilins and PilY1 regulate virulence by modulating FimS-AlgR activity

Marko, V. A.; Kilmury, S. L. N.; MacNeil, L. T.; Burrows, L. L.

10.1101/192062 — microbiology — Posted on 2018-04-01

2037 Multi-Link Analysis: Brain Network Comparison via Sparse Connectivity Analysis

Crimi, A.; Giancardo, L.; Sambataro, F.; Gozzi, A.; Murino, V.; Sona, D.

10.1101/277046 — neuroscience — Posted on 2018-04-01

2038 Leveraging chromatin accessibility for transcriptional regulatory network inference in T Helper 17 Cells

Miraldi, E. R.; Pokrovskii, M.; Watters, A.; Castro, D. M.; De Veaux, N.; Hall, J.; Lee, J.-Y.; Ciofani, M.; Madar, A.; Carriero, N.; Littman, D. R.; Bonneau, R.

10.1101/292987 — systems biology — Posted on 2018-04-01

2039 High resolution data-driven model of the mouse connectome

Knox, J. E.; Harris, K. D.; Graddis, N.; Whitesell, J. D.; Zeng, H.; Harris, J. A.; Shea-Brown, E.; Mihalas, S.

10.1101/293019 — neuroscience — Posted on 2018-04-01

2040 The organization of intracortical connections by layer and cell class in the mouse brain

Harris, J. A.; Mihalas, S.; Hirokawa, K. E.; Whitesell, J. D.; Knox, J.; Bernard, A.; Bohn, P.; Caldejon, S.; Casal, L.; Cho, A.; Feng, D.; Gaudreault, N.; Graddis, N.; Groblewski, P. A.; Henry, A.; Ho, A.; Howard, R.; Kuan, L.; Lecoq, J.; Luviano, J.; McConoghy, S.; Mortrud, M.; Naeemi, M.; Ng, L.; Oh, S. W.; Ouellette, B.; Sorensen, S.; Wakeman, W.; Wang, Q.; Williford, A.; Phillips, J.; Koch, C.; Zeng, H.

10.1101/292961 — neuroscience — Posted on 2018-04-01

2041 Population Genomics of Rapidly Invading Lionfish in the Caribbean Reveals Signals of Range Expansion in the Absence of Spatial Population Structure

Bors, E. K.; Herrera, S.; Morris, J. A.; Shank, T. M.

10.1101/291666 — evolutionary biology — Posted on 2018-04-01

2042 NRG1-mediated recognition of HopQ1 reveals a link between PAMP and Effector-triggered Immunity.

Brendolise, C.; Martinez-Sanchez, M.; Morel, A.; Chen, R.; Dinis, R.; Deroles, S.; Peeters, N.; Rikkerink, E. H. A.; Montefiori, M.

10.1101/293050 — plant biology — Posted on 2018-04-01

2043 CD56 expression of intravascular trophoblasts defines a class of vasculopathy in preeclampsia and other pregnancy complications

Zhang, P.

10.1101/293027 — pathology — Posted on 2018-04-01

2044 Adaptive coding for dynamic sensory inference

Mlynarski, W.; Hermundstad, A. M.

10.1101/189506 — neuroscience — Posted on 2018-04-01

2045 Neural dynamics at successive stages of the ventral visual stream are consistent with hierarchical error signals

Issa, E. B.; Cadieu, C. F.; DiCarlo, J. J.

10.1101/092551 — neuroscience — Posted on 2018-04-01

2046 A computational model of shared fine-scale structure in the human connectome

Guntupalli, J. S.; Feilong, M.; Haxby, J. V.

10.1101/108738 — neuroscience — Posted on 2018-04-01

2047 Intratumor Heterogeneity and Circulating Tumor Cell Clusters

Ahmed, Z.; Gravel, S.

10.1101/113480 — cancer biology — Posted on 2018-04-01

Archive, 2018-04