bioRxiv directory

Mahalingam, G.; Arjunan, P.; Periasami, Y.; Dhyani, A. K.; Devaraju, N.; Rajendiran, V.; Christopher, A. C.; KT, R. D.; Darasingh, I.; Thangavel, S.; Murugesan, M.; Moorthy, M.; Srivastava, A.; Marepally, S.

10.1101/2022.09.30.510287 — pharmacology and toxicology — Posted on 2022-09-30

16 Loss of ZNF251 stimulates NHEJ resulting in PARP inhibitor resistance in BRCA1-mutated cancer cells

Li, H.; Chatla, S.; Liu, X.; Walt, M.; Kim, D.; Lian, Z.; Morton, G.; Feng, Z.; Yang, D.; Liu, H.; Sullivan-Reed, K.; Childers, W.; Yu, X.; Madzo, J.; Chitrala, K. N.; Skorski, T.; Huang, J.

10.1101/2022.09.29.510119 — cancer biology — Posted on 2022-09-30

17 The SARS-CoV-2 mutation landscape is shaped before replication starts

Masone, D.; Alvarez, M. S.; Polo, L. M.

10.1101/2022.09.29.510149 — bioinformatics — Posted on 2022-09-30

18 Novel and simple simulation method to design and development of antisense template

Deo, D.; Shaikh, N.

10.1101/2022.09.30.510283 — bioinformatics — Posted on 2022-09-30

19 Genomic accordions may hold the key to Monkeypox Clade IIb's increased transmissibility

Monzon, S.; Varona, S.; Negredo, A.; Patino-Galindo, J. A.; Vidal-Freire, S.; Zaballos, A.; Orviz, E.; Ayerdi, O.; Munoz-Garcia, A.; Delgado-Iribarren, A.; Estrada, V.; Garcia, C.; Molero, F.; Sanchez, P.; Torres, M.; Vazquez, A.; Galan, J.-C.; Torres, I.; Causse del Rio, M.; Merino, L.; Lopez, M.; Galar, A.; Cardenoso, L.; Gutierrez, A.; Camacho, J.; Herrero, L.; Jimenez-Sancho, P.; Navarro-Rico, M. L.; Jado, I.; Kuhn, J.; Sanchez-Lockhart, M.; Di Paola, N.; Kugelman, J. R.; Giannetti, E.; Guerra, S.; Garcia-Sastre, A.; Palacios, G.; Sanchez-Seco, M.; Cuesta, I.

10.1101/2022.09.30.510261 — genomics — Posted on 2022-09-30

20 Maturation of SARS-CoV-2 Spike-specific memory B cells drives resilience to viral escape

Marzi, R.; Bassi, J.; Silacci-Fregni, C.; Bartha, I.; Muoio, F.; Culap, K.; Sprugasci, N.; Lombardo, G.; Saliba, C.; Cameroni, E.; Cassotta, A.; Low, J. S.; Walls, A. C.; McCallum, M.; Tortorici, M. A.; Bowen, J. E.; Dellota, E. A.; Dillen, J. R.; Czudnochowski, N.; Pertusini, L.; Terrot, T.; Lepori, V.; Tarkowski, M.; Riva, A.; Biggiogero, M.; Franzetti Pellanda, A.; Garzoni, C.; Ferrari, P.; Ceschi, A.; Giannini, O.; Havenar-Daughton, C.; Telenti, A.; Arvin, A.; Virgin, H. W.; Sallusto, F.; Veesler, D.; Lanzavecchia, A.; Corti, D.; Piccoli, L.

10.1101/2022.09.30.509852 — immunology — Posted on 2022-09-30

21 More than half of the variance in in-vivo 1H-MRS metabolite estimates is common to all metabolites

Prisciandaro, J. J.; Zöllner, H. J.; Murali-Manohar, S.; Oeltzschner, G.; Edden, R. A. E.

10.1101/2022.09.29.510115 — neuroscience — Posted on 2022-09-30

22 Technical insights into fluorescence lifetime microscopy of mechanosensitive Flipper probes

Roffay, C.; Garcia Arcos, J. M.; Chapuis, P.; Lopez-Andarias, J.; Colom, A.; Tomba, C.; Di Meglio, I.; Matile, S.; Roux, A.; Mercier, V.

10.1101/2022.09.28.509885 — biophysics — Posted on 2022-09-30

23 ROCA: AN ONTOLOGY FOR CAPTURING AND ANALYZING TOOL USE AND TOOL MAKING

Mercuriali, P. R.; Hernandez Corbato, C.; Langejans, G.

10.1101/2022.09.29.510031 — animal behavior and cognition — Posted on 2022-09-30

24 Brief Report: Prognostic relevance of 3q amplification in squamous cell carcinoma of the lung

Abu Rous, F.; Li, P.; Carskadon, S.; Singh, S. R.; Chacko, R.; Abushukair, H.; Gadgeel, S.; Palanisamy, N.

10.1101/2022.09.28.509728 — genomics — Posted on 2022-09-30

25 Meta-analysis of GWAS for sea lice load in Atlantic salmon

Caceres, P. A.; Lopez, P.; Garcia, B.; Cichero, D.; Odegard, J.; Moen, T.; Yanez, J.

10.1101/2022.09.28.509902 — genomics — Posted on 2022-09-30

26 Distribution of sex ratio distorters in natural populations of the isopod Armadillidium vulgare

Durand, S.; Lheraud, B.; Giraud, I.; Bech, N.; Grandjean, F.; Rigaud, T.; Peccoud, J.; Cordaux, R.

10.1101/2022.09.29.510044 — evolutionary biology — Posted on 2022-09-30

27 Rapid evolutionary diversification of the flamenco locus in the D. simulans clade

Signor, S.; Vedanayagam, J.; Wierzbicki, F.; Kofler, R.; Lai, E. C.

10.1101/2022.09.29.510127 — evolutionary biology — Posted on 2022-09-30

28 Consistent, linear phenological shifts across a century of observations in South Korea

Pearse, W. D.; Lee, B. R.; Stemkovski, M.; Primack, R. B.; Lee, S.

10.1101/2022.09.29.510037 — ecology — Posted on 2022-09-30

29 Plant attributes interact with fungal pathogens and nitrogen addition to drive soil enzymatic activities and their temporal variation

Nwe, T. Z.; Maaroufi, N. I.; Allan, E.; Soliveres, S.; Kempel, A.

10.1101/2022.09.29.510102 — ecology — Posted on 2022-09-30

30 Heritage of ancient cultures supports conservation: a continent-wide perspective from the Eurasian steppes

Deak, B.; Bede, A.; Radai, Z.; Dembicz, I.; Apostolova, I.; Batary, P.; Galle, R.; Toth, C. A.; Dozsai, J.; Moysiyenko, I. I.; Sudnik-Wojcikowska, B.; Nekhrizov, G.; Lisetskii, F. N.; Buryak, Z. A.; Kis, S.; Borza, S.; Godo, L.; Bragina, T. M.; Smelansky, I.; Molnar, A.; Ban, M.; Bathori, F.; Argay, Z.; Dani, J.; Valko, O.

10.1101/2022.09.29.510067 — ecology — Posted on 2022-09-30

31 Drivers and implications of the extreme 2022 wildfire season in Southwest Europe

RODRIGUES, M.; CUNILL CAMPRUBI, A.; BALAGUER-ROMANO, R.; RUFFAULT, J.; FERNANDES, P.; Resco de Dios, V.

10.1101/2022.09.29.510113 — ecology — Posted on 2022-09-30

32 Asymmetric distribution of centromere proteins between germline stem and daughter cells maintains a balanced niche in Drosophila males.

Kochendoerfer, A. M.; Dunleavy, E. M.

10.1101/2022.09.29.510087 — developmental biology — Posted on 2022-09-30

33 Fluctuations in chromatin state at regulatory loci occur spontaneously under relaxed selection and are associated with epigenetically inherited variation in C. elegans gene expression.

Wilson, R.; Le Bourgeois, M.; Perez, M. F.; Sarkies, P.

10.1101/2022.09.29.510125 — molecular biology — Posted on 2022-09-30

34 Diagnosis of type 2 Diabetes Mellitus (T2DM) using Paired microRNAs

Takada, Y.; Ono, Y.; Shibuta, T.; Ishibashi, A.; Takamori, A.; Fujimoto, K.; Hirooka, Y.; Umemura, T.

10.1101/2022.09.29.510072 — molecular biology — Posted on 2022-09-30

35 QUAS-R: Glutamine (Q) Uptake Assay with Single cell Resolution reveals metabolic heterogeneity with immune populations.

Pelgrom, L.; Davis, G.; O Shaughnessy, S.; Van Kasteren, S. I.; Finlay, D. K.; Sinclair, L. V.

10.1101/2022.09.29.510040 — immunology — Posted on 2022-09-30

36 Accurate measurement of inhibition and excitation in human motor pools during sensory stimulation

Soteropoulos, D.; Del Vecchio, A.

10.1101/2022.09.29.509858 — neuroscience — Posted on 2022-09-30

37 Neural correlates of extinction in a rat model of appetitive Pavlovian conditioning

Brown, A.; Villaruel, F. R.; Chaudhri, N.

10.1101/2022.09.28.509892 — neuroscience — Posted on 2022-09-30

38 Voxel-Wise Brain Graphs from Diffusion MRI: Intrinsic Eigenspace Dimensionality and Application to fMRI

Behjat, H.; Tarun, A.; Abramian, D.; Larsson, M.; Van De Ville, D.

10.1101/2022.09.29.510097 — neuroscience — Posted on 2022-09-30

39 Detection of orthologous genes with expression shifts linked to nickel hyperaccumulation across Eudicots

Gallopin, M.; Drevet, C.; Garcia de la Torre, V. S.; Jelassi, S.; Michel, M.; Ducos, C.; Saule, C.; Majorel, C.; Burtet-Sarramegna, V.; Pillon, Y.; Bastide, P.; Lespinet, O.; MERLOT, S.

10.1101/2022.09.28.509953 — plant biology — Posted on 2022-09-30

40 Bioenergetics of the secondary metabolites production in photosynthetic glandular trichomes

Saadat, N. P.; van Aalst, M.; Ebenhoeh, O.; Tissier, A. F.; Matuszynska, A. B.

10.1101/2022.09.29.510054 — plant biology — Posted on 2022-09-30

41 Tetraose glycoalkaloids from potato can provide complete protection against fungi and insects

Wolters, P. J.; Wouters, D.; Tikunov, Y. M.; Ayilalath, S.; Kodde, L. P.; Strijker, M.; Caarls, L.; Visser, R. G. F.; Vleeshouwers, V. G. A. A.

10.1101/2022.09.28.509958 — plant biology — Posted on 2022-09-30

42 Subchronic oral toxicity study of Aldicarb sulfoxide in Sprague-Dawley rats

Yongchao, J.; Yi, L.; Juanjuan, D.; Yiting, W.; Yu, W.; Fan, W.; Chao, C.; Wensheng, Z.

10.1101/2022.09.29.510057 — pharmacology and toxicology — Posted on 2022-09-30

43 Trends in Subcutaneous Tumour Height and Impact on Measurement Accuracy

Brough, D.; Amos, H.; Murkin, J.; Turley, K.

10.1101/2022.09.29.510123 — cancer biology — Posted on 2022-09-30

44 A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma

Noonan, H. R.; Barbano, J.; Xifaras, M.; Baron, C. S.; Yang, S.; Koczirka, K.; McConnell, A. M.; Zon, L. I.

10.1101/2022.09.29.510035 — cancer biology — Posted on 2022-09-30

45 Quantitative proteomics identifies tumour matrisome signatures in patients with non-small cell lung cancer

Titmarsh, H. F.; von Kriegsheim, A.; Wills, J. C.; O'Connor, R. A.; Dhaliwal, K.; Frame, M. C.; Pattle, S. B.; Dorward, D. A.; Byron, A.; Akram, A. R.

10.1101/2022.09.29.510064 — cancer biology — Posted on 2022-09-30

46 Regulation of chromatin microphase separation by adsorbed protein complexes

Adame-Arana, O.; Bajpai, G.; Lorber, D.; Volk, T.; Safran, S. A.

10.1101/2022.09.29.510124 — biophysics — Posted on 2022-09-30

47 Discovery of E6AP AZUL binding to UBQLN1/2 in cells, phase-separated droplets, and an AlphaFold-NMR integrated structure

Buel, G. R.; Chen, X.; Myint, W.; Kayode, O.; Folimonova, V.; Cruz, A.; Skorupka, K.; Matsuo, H.; Walters, K.

10.1101/2022.09.29.510132 — biophysics — Posted on 2022-09-30

48 Image recovery from unknown network mechanisms forDNA sequencing-based microscopy

Fernandez Bonet, D.; Hoffecker, I. T.

10.1101/2022.09.29.510142 — bioinformatics — Posted on 2022-09-30

49 Optimal feature selection and software tool development for bacteriocin prediction

Akhter, S.; Miller, J.

10.1101/2022.09.29.510068 — bioinformatics — Posted on 2022-09-30

50 Identify the origin and end cells and infer the trajectory of cellular fate automatically

Zeng, Z.; Xing, C.; Hu, L.; Shah, R.; Xiong, Y.; Du, H.

10.1101/2022.09.28.510020 — bioinformatics — Posted on 2022-09-30

51 From comparative gene content and gene order to ancestral contigs, chromosomes and karyotypes

Xu, Q.; Jin, L.; Zheng, C.; Zhang, X.; Leebens-Mack, J.; Sankoff, D.

10.1101/2022.09.28.509880 — bioinformatics — Posted on 2022-09-30

52 DeepBIO is an automated and interpretable deep-learning platform for biological sequence prediction, functional annotation, and visualization analysis

Wang, R.; Jiang, Y.; Jin, J.; Yin, C.; Yu, H.; Wang, F.; Feng, J.; Su, R.; Nakai, K.; Zou, Q.; Wei, L.

10.1101/2022.09.29.509859 — bioinformatics — Posted on 2022-09-30

53 Active Fixation as an Efficient Coding Strategy for Neuromorphic Vision

Testa, S.; Sabatini, S. P.; Canessa, A.

10.1101/2022.09.29.510091 — bioengineering — Posted on 2022-09-30

54 Predicting partner fitness based on spatial structuring in a light-driven microbial community

Sakkos, J. K.; Santos-Merino, M.; Kokarakis, E. J.; Li, B.; Fuentes-Cabrera, M.; Zuliani, P.; Ducat, D. C.

10.1101/2022.09.28.510001 — bioengineering — Posted on 2022-09-30

55 Asynchronous haltere input impairs wing and gaze control in Drosophila

Rauscher, M. J.; Fox, J. L.

10.1101/2022.09.29.509061 — animal behavior and cognition — Posted on 2022-09-30

56 Effects of antennal segments defects on blood-sucking behavior in Aedes albopictus

Zhou, Y.; Deng, D.; Chen, R.; Chen, Q.

10.1101/2022.09.29.510077 — animal behavior and cognition — Posted on 2022-09-30

57 A high quality chromosome-level genome assembly for the golden mussel (Limnoperna fortunei)

Rodinho Nunes Ferreira, J. G.; Americo, J. A.; Amaral, D. L. A. S.; Sendim, F.; da Cunha, Y. R.; The Darwin Tree of Life Project Consortium, ; Uliano-Silva, M.; Rebelo, M. d. F.

10.1101/2022.09.29.509984 — genomics — Posted on 2022-09-30

58 King- and queen-specific degradation of uric acid is the key to reproduction in termites

Konishi, T.; Tasaki, E.; Takata, M.; Matsuura, K.

10.1101/2022.09.28.510009 — ecology — Posted on 2022-09-30

59 Large-scale assessment of habitat quality and quantity change on declining European butterflies

Chazot, N.; Faurby, S.; van Swaay, C.; Ekroos, J.; Wahlberg, N.; Bacon, C. D.; Antonelli, A.

10.1101/2022.09.29.510048 — ecology — Posted on 2022-09-30

60 Clarifying space use concepts in ecology: range vs. occurrence distributions

Alston, J. M.; Fleming, C. H.; Noonan, M. J.; Tucker, M. A.; Silva, I.; Folta, C.; Akre, T. S.; Ali, A. H.; Belant, J. L.; Beyer, D.; Blaum, N.; Boehning-Gaese, K.; Cunha de Paula, R.; Dekker, J.; Drescher-Lehman, J.; Farwig, N.; Fichtel, C.; Fischer, C.; Ford, A. T.; Janssen, R.; Jeltsch, F.; Kappeler, P. M.; LaPoint, S. D.; Markham, A. C.; Medici, P.; Morato, R. G.; Nathan, R.; Olson, K.; Patterson, B. D.; Petroelje, T.; Ramalho, E. E.; Roesner, S.; Santos, L. G. R. O.; Schabo, D. G.; Selva, N.; Sergiel, A.; Spiegel, O.; Ullman, W.; Zieba, F.; Zwijacz-Kozica, T.; Wittemyer, G.; Fagan, W. F.;

10.1101/2022.09.29.509951 — ecology — Posted on 2022-09-30

61 Universal Amplicon Sequencing of North Imperial Valley Wetlands Microbiomes

Becker, S. A.; Graham, E.; Sager, L.; Spreafico, R.; McCarren, J.

10.1101/2022.09.29.509762 — ecology — Posted on 2022-09-30

62 Cellular Factors Involved in Transcriptome Dynamics in Early Zebrafish Embryogenesis

Rauwerda, H.; Pagano, J. F. B.; de Leeuw, W. C.; Ensink, W.; van Olst, M.; Nehrdich, U.; Jonker, M. J.; Spaink, H. P.; Breit, T. M.

10.1101/2022.09.29.510050 — developmental biology — Posted on 2022-09-30

63 Lineage segregation in human pre-implantation embryos is specified by YAP1 and TEAD1

Regin, M.; Essahib, W.; Demtschenko, A.; Dewandre, D.; David, L.; Gerri, C.; Niakan, K.; Verheyen, G.; Tournaye, H.; Sterckx, J.; Sermon, K.; Van de Velde, H.

10.1101/2022.09.29.509946 — developmental biology — Posted on 2022-09-30

64 Capsid structure of a metazoan fungal dsRNA megabirnavirus reveals its uniquely acquired structures

Wang, H.; Salaipeth, L.; Miyazaki, N.; Suzuki, N.; Okamoto, K.

10.1101/2022.09.29.510062 — molecular biology — Posted on 2022-09-30

65 Methotrexate inhibition of muropeptide transporter SLC46A2 controls psoriatic skin inflammation

Bharadwaj, R.; Lusi, C. F.; Mashayekh, S.; Nagar, A.; Malireddi, R. K. S.; Kane, G. I.; Wodzanowski, K.; Brown, A.; Okuda, K.; Monahan, A.; Paik, D.; Nandy, A.; Anonick, M.; Goldman, W. E.; Kanneganti, T.-D.; Orzalli, M. H.; Grimes, C. L.; Atukorale, P. U.; Silverman, N.

10.1101/2022.09.29.509906 — immunology — Posted on 2022-09-30

66 Changes in lung sialidases in male and female mice after bleomycin aspiration

Pilling, D.; Sahlberg, K.; Chen, W.; Gomer, R. H.

10.1101/2022.09.29.510121 — immunology — Posted on 2022-09-30

67 Decoding of the speech envelope from EEG using the VLAAI deep neural network.

Accou, B.; Vanthornhout, J.; Van hamme, H.; Francart, T.

10.1101/2022.09.28.509945 — neuroscience — Posted on 2022-09-30

68 MicroRNA-335-5p suppresses voltage-gated sodium channel expression and may be a target for seizure control

Heiland, M.; Connolly, N. M. C.; Nguyen, N. T.; Kesavan, J. C.; Fanning, K.; Sanfeliu, A.; Yan, Y.; Veno, M. T.; Costard, L. S.; Neubert, V.; Hill, T. D. M.; Rosenow, F.; Bauer, S.; Kjems, J.; Morris, G.; Henshall, D.

10.1101/2022.09.29.510105 — neuroscience — Posted on 2022-09-30

69 Dopamine regulates decision thresholds in human reinforcement learning.

Chakroun, K.; Wiehler, A.; Wagner, B.; Mathar, D.; Ganzer, F.; vanEimeren, T.; Sommer, T.; Peters, J.

10.1101/2022.09.29.509499 — neuroscience — Posted on 2022-09-30

70 Phosphatidylserine controls synaptic targeting and membrane stability of ASIC1a

Liu, D.-S.; Song, X.-L.; Liu, M.-G.; Lu, J.; Huang, Y.; Jeon, J.; Ma, G.; Li, Y.; Pozzo-Miller, L.; Zhu, M. X.; Xu, T.-L.

10.1101/2022.09.29.509830 — neuroscience — Posted on 2022-09-30

71 Macaque amygdala, claustrum and pulvinar support the cross-modal association of social audio-visual stimuli based on meaning

Froesel, M.; Gacoin, M.; Clavagnier, S.; Hauser, M.; Goudard, Q.; Ben Hamed, S.

10.1101/2022.09.28.509981 — neuroscience — Posted on 2022-09-30

72 Apolipoprotein E4 modulates astrocyte neuronal support functions in the presence of amyloid-β

Fleeman, R. M.; Kuhn, M. K.; Chan, D. C.; Proctor, E. A.

10.1101/2022.09.29.510145 — neuroscience — Posted on 2022-09-30

73 Synapsing with oligodendrocyte precursor cells stop sensory axons regenerating into the spinal cord

Kim, H.; Skuba, A.; Xia, J.; Han, S. B.; Zhai, J.; Yoo, R.; Hu, H.; Kang, S. H.; Son, Y.-J.

10.1101/2022.09.28.509944 — neuroscience — Posted on 2022-09-30

74 Brain-wide associations between white matter and agehighlight the role of fornix microstructure in brain age

Korbmacher, M.; de Lange, A. M.; van der Meer, D.; Beck, D.; Eikefjord, E. N.; Lundervold, A.; Andreassen, O.; Westlye, L. T.; Maximov, I. I.

10.1101/2022.09.29.510029 — neuroscience — Posted on 2022-09-30

75 Low-dimensional organization of global brain states of reduced consciousness

Perl, Y. S.; Pallavicini, C.; Piccinini, J.; Demertzi, A.; Bonhomme, V.; Martial, C.; Panda, R.; Alnagger, N.; Annen, J.; Gosseries, O.; Ibanez, A.; Laufs, H.; Sitt, J.; Jirsa, V.; Kringelbach, M. L.; Laureys, S.; Deco, G.; Tagliazucchi, E.

10.1101/2022.09.28.509817 — neuroscience — Posted on 2022-09-30

76 The trait coding rule in phenotype space

Wang, J.; He, X.

10.1101/2022.09.29.510032 — systems biology — Posted on 2022-09-30

77 Comprehensive analysis of intercellular communication in thermogenic adipose niche

Shamsi, F.; Zheng, R.; Ho, L.-L.; Chen, K.; Tseng, Y.-H.

10.1101/2022.09.28.509990 — systems biology — Posted on 2022-09-30

78 CLPB3 is required for the removal of chloroplast protein aggregates and for thermotolerance in Chlamydomonas

Kreis, E.; Niemeyer, J.; Merz, M.; Scheuring, D.; Schroda, M.

10.1101/2022.09.28.509957 — plant biology — Posted on 2022-09-30

79 Validity of Optical Heart Rate Measurement in Commercially Available Wearable Fitness Tracking Devices

Thomas, J.; Doyle, P.; Doyle, A.

10.1101/2022.09.29.510075 — physiology — Posted on 2022-09-30

80 Multi-modal digital pathology for colorectal cancer diagnosis by high-plex immunofluorescence imaging and traditional histology of the same tissue section

Lin, J.-R.; Chen, Y.-A.; Campton, D.; Cooper, J.; Coy, S.; Yapp, C.; Tefft, J.; McCarty, E.; Ligon, K.; Rodig, S. J.; Reese, S.; George, T.; Santagata, S.; Sorger, P. K.

10.1101/2022.09.28.509927 — cancer biology — Posted on 2022-09-30

81 Membrane Protein Modification Modulates Big and Small Extracellular Vesicle Biodistribution and Tumorigenic Potential in Breast Cancers In Vivo

Magoling, B. J. A.; Chen, Y.-J.; Wu, A. Y.-T.; Wong, W. W.-T.; Chuo, S. T.-Y.; Huang, H.-C.; Sung, Y.-C.; Hsieh, H.-T.; Huang, P.; Lee, K.-Z.; Huang, K.-W.; Chen, R.-H.; Chen, Y.; Lai, C. P.

10.1101/2022.09.28.510006 — cancer biology — Posted on 2022-09-30

82 Aberrant DNA repair is a vulnerability in histone H3.3-mutant brain tumors

Rondinelli, B.; Giacomini, G.; Piquet, S.; Chevallier, O.; Dabin, J.; Bai, S.-K.; Kim, B.; Siddaway, R.; Raught, B.; Coyaud, E.; Shan, C.-M.; Reid, R. J. D.; Toda, T.; Rothstein, R.; Wilhelm, T.; Barra, V.; Crane, A.; Dubois, F.; Bandopadhayay, P.; Beroukhim, R.; Naim, V.; Jia, S.; Hawkins, C.; Polo, S. E.

10.1101/2022.09.29.510093 — cancer biology — Posted on 2022-09-30

83 A NOVEL UNBIASED SEED-BASED RNAi SCREEN IDENTIFIES SMALL RNAs THAT INHIBIT ANDROGEN SIGNALING AND PROSTATE CANCER CELL GROWTH

Corbin, J. M.; Georgescu, C.; Wang, L.; Wren, J. D.; Bieniasz, M.; Xu, C.; Asch, A. S.; Ruiz Echevarria, M. J.

10.1101/2022.09.29.510140 — cancer biology — Posted on 2022-09-30

84 Location of CD39+ T cell sub-populations within tumours predict differential outcomes in non-small cell lung cancer.

Koppensteiner, L.; Mathieson, L.; Pattle, S.; Dorward, D. A.; O'Connor, R.; Akram, A. R.

10.1101/2022.09.29.509921 — cancer biology — Posted on 2022-09-30

85 LKB1 loss rewires JNK-induced apoptotic protein dynamics through NUAKs and sensitizes KRAS-mutant NSCLC to combined KRASG12C + MCL-1 blockade

Li, C.; Syed, M. U.; Shen, Y.; Fraser, C.; Ouyang, J.; Kreuzer, J.; Clark, S. E.; Oh, A.; Walcott, M.; Morris, R.; Nabel, C.; Caenepeel, S.; Saiki, A. Y.; Rex, K.; Lipford, J. R.; Heist, R. S.; Lin, J. J.; Haas, W.; Sarosiek, K.; Hughes, P. E.; Hata, A. N.

10.1101/2022.09.29.510137 — cancer biology — Posted on 2022-09-30

86 A tradeoff between enterovirus A71 particle stability and cell entry

Catching, A.; Yeh, M. T.; Bianco, S.; Capponi, S.; Andino, R.

10.1101/2022.09.28.506941 — biophysics — Posted on 2022-09-30

87 Emergent chirality in active solid rotation of pancreas spheres

Tan, T. H.; Amiri, A.; Seijo-Barandiaran, I.; Staddon, M. F.; Materne, A.; Tomas, S.; Duclut, C.; Popovic, M.; Grapin-Botton, A.; Jülicher, F.

10.1101/2022.09.29.510101 — biophysics — Posted on 2022-09-30

88 Over Two Million Protein Translocations Reveal Optimal Conditions for High Bandwidth Recordings, Studying Transport Energetics, and Electric-Field Unfolding

Bandara, N.; Freedman, K.

10.1101/2022.09.28.509929 — biophysics — Posted on 2022-09-30

89 Mass spectrometry of RNA-binding proteins during liquid-liquid phase separation reveals distinct assembly mechanisms and droplet architectures

Sahin, C.; Motso, A.; Gu, X.; Feyrer, H.; Lama, D.; Arndt, T.; Rising, A.; Gese, G. V.; Hällberg, B. M.; Marklund, E. G.; Schafer, N. P.; Petzold, K.; Teilum, K.; Wolynes, P. G.; Landreh, M.

10.1101/2022.09.28.509878 — biophysics — Posted on 2022-09-30

90 Kinetic relaxation of giant vesicles validates diffusional softening in a binary lipid mixture

Sapp, K. A.; Aleksanyan, M.; Kerr, K.; Dimova, R.; Sodt, A. J.

10.1101/2022.09.28.509943 — biophysics — Posted on 2022-09-30

91 Single-particle tracking and machine-learning classification reveals heterogeneous Piezo1 diffusion

Tyagi, V.; Ly, A. T.; Bertaccini, G. A.; Evans, E. L.; Freites, J. A.; Tobias, D. J.; Pathak, M. M.

10.1101/2022.09.30.510193 — biophysics — Posted on 2022-09-30

92 Treenome Browser: co-visualization of enormous phylogenies and millions of genomes

Kramer, A. M.; Sanderson, T.; Corbett-Detig, R.

10.1101/2022.09.28.509985 — bioinformatics — Posted on 2022-09-30

93 TIVAN-indel: A computational framework for annotating and predicting noncoding regulatory small insertion and deletion

Chen, L.; Agarwal, A.

10.1101/2022.09.28.509993 — bioinformatics — Posted on 2022-09-30

94 Multiomics reveal that silk fibroin and sericin differentially potentiate the paracrine functions of mesenchymal stem cells and enhance tissue regeneration

Zhang, Y.; Sheng, R.; Chen, J.; Wang, H.; Zhu, Y.; Cao, Z.; Zhao, X.; Wang, Z.; Liu, C.; Chen, Z.; Zhang, P.; Kuang, B.; Zheng, H.; Yao, Q.; Zhang, W.

10.1101/2022.09.29.510013 — bioengineering — Posted on 2022-09-30

95 Genetically Encoded RNA-based Bioluminescence Resonance Energy Transfer (BRET) Sensors

Mi, L.; Yu, Q.; Mudiyanselage, A. P. K. K. K.; Wu, R.; Sun, Z.; Zheng, R.; Ren, K.; You, M.

10.1101/2022.09.28.509942 — bioengineering — Posted on 2022-09-30

96 Assessment of pre-clinical liver models based on their ability to predict the liver-tropism of AAV vectors

Westhaus, A.; Cabanes-Creus, M.; Dilworth, K. L.; Zhu, E.; Salas Gomez, D.; Navarro, R. G.; Amaya, A. K.; Scott, S.; Kwiatek, M.; McCorkindale, A. L.; Hayman, T. E.; Frahm, S.; Perocheau, D. P.; Tran, B. M.; Vincan, E.; Wong, S. L.; Waters, S. A.; Wilson, L. O. W.; Baruteau, J.; Diecke, S.; Gonzalez-Aseguinolaza, G.; Santilli, G.; Thrasher, A. J.; Alexander, I. E.; Lisowski, L.

10.1101/2022.09.28.510021 — bioengineering — Posted on 2022-09-30

97 Enteroviral 2C protein is an RNA-stimulated ATPase and uses a two-step mechanism for binding to RNA and ATP

Yeager, C.; Carter, G.; Gohara, D. W.; Yennawar, N. H.; Enemark, E. J.; Arnold, J. J.; Cameron, C. E.

10.1101/2022.09.28.509975 — biochemistry — Posted on 2022-09-30

98 Nanoscale Friction of Model Hair Surfaces

Weiand, E.; Ewen, J. P.; Roiter, Y.; Koenig, P. H.; Page, S. H.; Rodriquez-Ropero, F.; Angioletti-Uberti, S.; Dini, D.

10.1101/2022.09.29.510078 — biochemistry — Posted on 2022-09-30

99 Poor attentional control as a sex-specific biomarker to assess vulnerability to nicotine addiction in mice

Medrano, M.-C.; Darlot, F.; Cador, M.; Caille, S.

10.1101/2022.09.29.510104 — animal behavior and cognition — Posted on 2022-09-30

100 Parental pericentromeric methylation status drives methylome remodelling and heterosis in epigenetic hybrids

Kakoulidou, I.; Piecyk, R. S.; Meyer, R. C.; Kuhlmann, M.; Altmann, T.; Gutjahr, C.; Johannes, F.

10.1101/2022.09.29.510107 — genomics — Posted on 2022-09-30

101 Chromosome-scale genome assembly of a Japanese chili pepper landrace, Capsicum annuum 'Takanotsume'

Shirasawa, K.; Hosokawa, M.; Yasui, Y.; Toyoda, A.; Isobe, S.

10.1101/2022.09.30.510245 — genomics — Posted on 2022-09-30

102 Transposon wave remodelled the epigenomic landscape in the rapid evolution of a novel X chromosome dosage compensation mechanism

Metzger, D. C.; Porter, I.; Sandkam, B. A.; Fong, L. J.; Mank, J. E.

10.1101/2022.09.29.510218 — genomics — Posted on 2022-09-30

103 Including both sexes in in vivo research does not necessitate an increase in sample size: a key role for factorial analysis methods

Phillips, B.; Haschler, T.; Karp, N.

10.1101/2022.09.29.510061 — genetics — Posted on 2022-09-30

104 RACK1 may participate in placental development via regulating proliferation and migration of trophoblast cell in pigs following intrauterine growth restriction

Wu, Z.; Hu, G.; Gong, T.; Hu, Q.; Hong, L.; Zhang, Y.; Ao, Z.

10.1101/2022.09.29.510071 — genetics — Posted on 2022-09-30

105 Fully efficient, two-stage analysis of multi-environment trials with directional dominance and multi-trait genomic selection

Endelman, J. B.

10.1101/2022.09.28.509884 — genetics — Posted on 2022-09-30

106 evosim: fast and scalable stochastic simulations of evolutionary dynamics

Engelhardt, D.; McDonald, T. O.

10.1101/2022.09.28.509950 — evolutionary biology — Posted on 2022-09-30

107 Coinfection with chytrid genotypes drives divergent infection dynamics reflecting broad epidemiological patterns

Carvalho, T.; Medina, D.; Ribeiro, L. P.; Rodriguez, D.; Jenkinson, T. S.; Becker, G.; Toledo, L. F.; Hite, J.

10.1101/2022.09.28.509987 — ecology — Posted on 2022-09-30

108 Process-guidance improves predictive performance of neural networks for carbon turnover in ecosystems

Wesselkamp, M.; Moser, N. N.; Kalweit, M.; Boedecker, J.; Dormann, C. F.

10.1101/2022.09.28.509877 — ecology — Posted on 2022-09-30

109 Anglers as Potential Vectors of Aquatic Invasive Species: Linking Inland Water Bodies in the Great Lakes Region of the US.

Morreale, S. J.; Lauber, T. B.; Stedman, R. C.

10.1101/2022.09.29.510070 — ecology — Posted on 2022-09-30

110 Determining the Role of Environmental Covariates on Planktivorous Elasmobranch Population Trends within an Isolated Marine Protected Area

Saltzman, J.; White, E. R.

10.1101/2022.09.28.509935 — ecology — Posted on 2022-09-30

111 Beyond the metropolis: Street tree densities and resident perceptions on ecosystem services in small urban centers in India

Anujan, K.; Velho, N.; Kuriakose, G.; P J, E.; Nagendra, H.

10.1101/2022.09.28.509699 — ecology — Posted on 2022-09-30

112 Hypodermal ribosome synthesis inhibition induces a nutrition-uncoupled organism-wide growth quiescence

Zhao, Q.; Rangan, R.; Weng, S.; Ozdemir, C.; Cenik, E. S.

10.1101/2022.09.28.509886 — developmental biology — Posted on 2022-09-30

113 Balancing competing effects of tissue growth and cytoskeletal regulation during Drosophila wing disc development

Kumar, N.; Tsai, K.; Mim, M. S.; Ambriz, J. R.; Chen, W.; Zartman, J. J.; Alber, M.

10.1101/2022.09.28.509971 — developmental biology — Posted on 2022-09-30

114 Hematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic hemogenic endothelium

Ghersi, J. J.; Baldissera, g.; Hintzen, J.; Luff, S. A.; Cheng, S.; Xia, I. F.; Sturgeon, C. M.; Nicoli, S.

10.1101/2022.09.28.509963 — developmental biology — Posted on 2022-09-30

115 Efficient and scalable generation of primordial germ cells in 2D culture using basement membrane extract overlay

Overeem, A. W.; Chang, Y. W.; Moustakas, I.; Roelse, C. M.; Hillenius, S.; van der Helm, T.; van der Schrier, V. F.; Mei, H.; Freund, C.; Chuva de Sousa Lopes, S. M.

10.1101/2022.09.28.509976 — developmental biology — Posted on 2022-09-30

116 Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1

Dwivedi, D.; Harry, D.; Meraldi, P.

10.1101/2022.09.29.510042 — cell biology — Posted on 2022-09-30

117 Detyrosination enrichment on microtubule subsets is established by the interplay between a stochastically-acting enzyme and microtubule stability

Tang, Q.; Sensale, S.; Bond, C.; Qiao, A.; Hugelier, S.; Arab, A.; Arya, G.; Lakadamyali, M.

10.1101/2022.09.29.510213 — cell biology — Posted on 2022-09-30

118 Circadian regulation of protein turnover and proteome renewal

Seinkmane, E.; Peak-Chew, S. Y.; Zeng, A.; Rzechorzek, N. M.; Beale, A. D.; Wong, D. C.; O'Neill, J. S.

10.1101/2022.09.30.509905 — cell biology — Posted on 2022-09-30

119 YAP1 is essential for self-organized differentiation of pluripotent stem cells

Zeevaert, K.; Goetzke, R.; Elsafi Mabrouk, M. H.; Schmidt, M.; Maassen, C.; Henneke, A.-C.; He, C.; Gillner, A.; Zenke, M.; Wagner, W.

10.1101/2022.09.29.510043 — cell biology — Posted on 2022-09-30

120 Concomitant Vascular Calsequestrin 2 overexpression and leukocytes transmigration in a rat model of skeletal muscle traumatic inflammatory injury

Ben Khalaf, N.; Al-Mehatab, D.; M. Fathallah, D.

10.1101/2022.09.29.510069 — molecular biology — Posted on 2022-09-30

121 30-Minute Highly Multiplexed VaxArray Immunoassay for Pneumococcal Vaccine Antigen Characterization

Hu, T.; Miller, D. F.; Taylor, A. W.; McCormick, C.; Thomas, K. N.; Gao, R. Y.; Rowlen, K.; Kim, S. K.; Byrne, E. B.; Kumar, P.; Riley, C.; Dawson, E. D.

10.1101/2022.09.28.509947 — immunology — Posted on 2022-09-30

122 Metabolic plasticity of T-cell therapies: multi-omic profiling of interacting human tumor-infiltrating lymphocytes and autologous tumor adoptive cell therapy

Martinez-Paniagua, M.; Haymaker, C.; Robinson, J.; Harel, M.; Creasy, C.; Adolacion, J. R. T.; An, X.; Fathi, M.; Rezvan, A.; Kumar, M.; Amritkar, A.; Woodman, S. E.; Amaria, R. N.; Geiger, T.; Hwu, P.; Bernatchez, C.; Varadarajan, N.

10.1101/2022.09.28.509590 — immunology — Posted on 2022-09-30

123 Cross-reactive single-domain antibodies to hemagglutinin stem region protect mice from group 1 influenza A virus infection

Voronina, D. V.; Bandelyuk, A. S.; Dzharullaeva, A. S.; Popova, O.; Kan, V. Y.; Esmagambetov, I. B.; Favorskaya, I. A.; Shcheblyakov, D. V.; Naroditskiy, B. S.; Gintsburg, A. L.

10.1101/2022.09.29.510074 — immunology — Posted on 2022-09-30

124 pCREB-Per2 pathway in hippocampal CA1 region mediates the transition of depression and mania-like behaviors in rats

Wang, X.-L.

10.1101/2022.09.28.509998 — neuroscience — Posted on 2022-09-30

125 Subpopulation Codes Permit Information Modulation Across Cortical States

Getz, M. P.; Huang, C.; Doiron, B.

10.1101/2022.09.28.509815 — neuroscience — Posted on 2022-09-30

126 Male and Female Brain Coherence Models of Cognitive Performance and Psychopathology

Dumitru, M. L.; Korbmacher, M.; Bartsch, H.

10.1101/2022.09.28.509939 — neuroscience — Posted on 2022-09-30

127 The BeMoBIL Pipeline for automated analyses of multimodal mobile brain and body imaging data

Klug, M.; Jeung, S.; Wunderlich, A.; Gehrke, L.; Protzak, J.; Djebbara, Z.; Argubi-Wollesen, A.; Wollesen, B.; Gramann, K.

10.1101/2022.09.29.510051 — neuroscience — Posted on 2022-09-30

128 Fluorescence lifetime enables high-resolution analysis of neuromodulator dynamics across time and animals

Ma, P.; Chen, P.; Tilden, E.; Aggarwal, S.; Oldenborg, A.; Chen, Y.

10.1101/2022.09.28.510014 — neuroscience — Posted on 2022-09-30

129 Examination of Onset Trajectories and Persistence of Binge-Like Eating Behavior in Mice after Intermittent Palatable Food Exposure

Hildebrandt, B. A.; Fisher, H.; Ahmari, S. E.

10.1101/2022.09.28.510003 — neuroscience — Posted on 2022-09-30

130 kcna1a mutant zebrafish as a model of episodic ataxia type 1 and epilepsy

Dogra, D.; Meza-Santoscoy, P. L.; Rehak, R.; de la Hoz, C. L. R.; Gavrilovici, C.; Ibhazehiebo, K.; Rho, J. M.; Kurrasch, D. M.

10.1101/2022.09.28.509973 — neuroscience — Posted on 2022-09-30

131 Accurate Bayesian segmentation of thalamic nuclei using diffusion MRI and an improved histological atlas

Tregidgo, H. F. J.; Soskic, S.; Althonayan, J.; Maffei, C.; Van Leemput, K.; Golland, P.; Yendiki, A.; Alexander, D. C.; Bocchetta, M.; Rohrer, J. D.; Iglesias, J. E.

10.1101/2022.09.28.508731 — neuroscience — Posted on 2022-09-30

132 Electrophile scanning by chemical proteomics reveals a potent pan-active DUB probe for investigation of deubiquitinase activity in live cells

Conole, D. P.; Cao, F.; Am Ende, C. W.; Xue, L.; Kantesaria, S.; Kang, D.; Jin, J.; Owen, D. P.; Lohr, L. L.; Schenone, M.; Majmudar, J. D.; Tate, E. W.

10.1101/2022.09.28.509970 — systems biology — Posted on 2022-09-30

133 A novel CLAVATA1 mutation causes multilocularity in Brassica rapa

Chow, H. T.; Kendall, T.; Mosher, R. A.

10.1101/2022.09.28.509982 — plant biology — Posted on 2022-09-30

134 Using Machine Learning Enabled Phenotyping To Characterize Nodulation In Three Early Vegetative Stages In Soybean

Carley, C.; Zubrod, M.; Dutta, S.; Singh, A. K.

10.1101/2022.09.28.509969 — plant biology — Posted on 2022-09-30

135 The N-terminal extension of Arabidopsis ARGONAUTE 1 is essential for microRNA activities

Xu, Y.; Zhang, Y.; Li, Z.; Soloria, A.; Potter, S.; Chen, X.

10.1101/2022.09.29.510030 — plant biology — Posted on 2022-09-30

136 Prediction and Classification of the Uptake and Disposition of Antidepressants and New CNS-Active Drugs in the Human Brain using the ANDROMEDA by Prosilico Software and Brainavailability-Matrix

Fagerholm, U.; Hellberg, S.; Alvarsson, J.; Spjuth, O.

10.1101/2022.09.28.509936 — pharmacology and toxicology — Posted on 2022-09-30

137 ClickArr: a novel, high throughput assay for evaluating β-arrestin isoform recruitment

French, A. R.; Meqbil, Y. J.; van Rijn, R. M.

10.1101/2022.09.28.509965 — pharmacology and toxicology — Posted on 2022-09-30

138 Type 1 interferon remodels normal and neoplastic hematopoiesis in human

Lama, C.; Rosenberg, S.; Kubas-Meyer, A.; Xie, X. A.; Moein, S.; Parghi, N.; Totwani, M.; Saurty-Seerunghen, M. S.; Omar, M.; Dillard, A.; Omans, N. D.; Dusaj, N. N.; Chamely, P.; Mimitou, E.; Smibert, P.; Kosiorek, H. E.; Dueck, A. C.; Weinberg, R.; Chaligne, R.; Marchionni, L.; Patel, S.; Simonson, P. D.; Landau, D. A.; Hoffman, R.; Nam, A. S.

10.1101/2022.09.28.509751 — cancer biology — Posted on 2022-09-30

139 Small Molecule Assembly Modulators with Pan-Cancer Therapeutic Efficacy

Lingappa, A. F.; Akintunde, O.; Ewald, C.; Froehlich, M.; Ziari, N.; Yu, S. F.; Michon, M.; Mallesh, S.; Lin, J.; Kitaygorodskyy, A.; Solas, D.; Reed, J. C.; Lingappa, J. R.; Mueller-Schiffmann, A.; Korth, C.; Prasad, M. D.; Ashton, E.; Fabbri, B.; Nalca, A.; Petrouski, E.; Dey, D.; Andrews, D. W.; Lingappa, V. R.

10.1101/2022.09.28.509937 — cancer biology — Posted on 2022-09-30

140 Biogenic plate-like guanine crystals form via templated nucleation of thin crystal leaflets on amyloid scaffolds

Eyal, Z.; Deis, R.; Varsano, N.; Dezorella, N.; Rechav, K.; Houben, L.; Gur, D.

10.1101/2022.09.29.510168 — biophysics — Posted on 2022-09-30

141 Gentle and fast all-atom model refinement to cryo-EM densities via Bayes' approach

Blau, C.; Yvonnesdotter, L.; Lindahl, E.

10.1101/2022.09.30.510249 — biophysics — Posted on 2022-09-30

142 Automated STED nanoscopy for high-throughput imaging of cellular structures

Mol, F. N.; Vlijm, R.

10.1101/2022.09.29.510126 — biophysics — Posted on 2022-09-30

143 Minimizing the elastic energy of growing leaves by conformal mapping

Dai, A.; Ben Amar, M.

10.1101/2022.09.28.509914 — biophysics — Posted on 2022-09-30

144 Strong positive allometry of bite force in leaf-cutter ants increases the range of cuttable plant tissues

Pueffel, F.; Roces, F.; Labonte, D.

10.1101/2022.09.28.509980 — biophysics — Posted on 2022-09-30

145 Machine learning prediction models for nutrient profiles in food after processing

NARAVANE, T.; Tagkopoulos, I.

10.1101/2022.09.28.509827 — bioinformatics — Posted on 2022-09-30

146 Significantly amplified photoacoustic effect for silica-coated gold nanoparticles by interface heat transfer mechanisms

Youn, J.; Kang, P.; Wilson, B.; Xie, C.; Basavarajappa, L.; Wang, Q.; Kim, M.; Hoyt, K.; Qin, Z.

10.1101/2022.09.28.509922 — bioengineering — Posted on 2022-09-30

147 Temperature-triggered in situ forming lipid mesophase gel for local treatment of ulcerative colitis

Carone, M.; Spalinger, M. R.; Gaultney, R. A.; Mookhoek, A.; Krebs, P.; Rogler, G.; Luciani, P.; Aleandri, S.

10.1101/2022.09.28.509483 — bioengineering — Posted on 2022-09-30

148 Digital Light Processing 3D printing for biological applications of polydimethylsiloxane-based microfluidics

Poskus, M.; Wang, T.; Deng, Y.; Borcherding, S.; Zervantonakis, I.

10.1101/2022.09.28.509779 — bioengineering — Posted on 2022-09-30

149 Horizontal detection of post-translational modifications to an amino acid with a nanopore based on analyte volume and translocation-time

Sampath, G.

10.1101/2022.09.28.507994 — bioengineering — Posted on 2022-09-30

150 A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in the human and mouse brains

Sziraki, A.; Lu, Z.; Lee, J.; Banyai, G.; Anderson, S.; Abdulraouf, A.; Metzner, E.; Liao, A.; Epstein, A.; Xu, Z.; Zhang, Z.; Gan, L.; Nelson, P. T.; Zhou, W.; Cao, J.

10.1101/2022.09.28.509825 — genomics — Posted on 2022-09-30

151 Differentially expressed tRNA-derived fragments in bovine fetuses with assisted reproduction induced congenital overgrowth syndrome

Goldkamp, A. K.; Li, Y.; Rivera, R. M.; Hagen, D. E.

10.1101/2022.09.28.509974 — genomics — Posted on 2022-09-30

152 Selection and adaptive introgression guided the complex evolutionary history of European common bean

Bellucci, E.; Benazzo, A.; Xu, C.; Bitocchi, E.; Rodriguez, M.; Alseekh, S.; Di Vittori, V.; Gioia, T.; Neumann, K.; Cortinovis, G.; Frascarelli, G.; Murube, E.; Trucchi, E.; Nanni, L.; Ariani, A.; Logozzo, G.; Shin, J. H.; Liu, C.; Jiang, L.; Ferreira, J. J.; Campa, A.; Attene, G.; Morrell, P. L.; Bertorelle, G.; Graner, A.; Gepts, P.; Fernie, A. R.; Jackson, S. A.; Papa, R.

10.1101/2022.09.28.509856 — genomics — Posted on 2022-09-30

153 Chromosome-scale reference genome and RAD-based genetic map of yellow starthistle (Centaurea solstitialis) reveal putative structural variation and QTLs associated with invader traits

Reatini, B.; Cang, F. A.; Jiang, Q.; McKibben, M. T. W.; Barker, M. S.; Rieseberg, L. H.; Dlugosch, K. M.

10.1101/2022.09.28.509992 — genomics — Posted on 2022-09-30

154 Simultaneous Inference of Past Demography and Selection from the Ancestral Recombination Graph under the Beta Coalescent

Korfmann, K.; Sellinger, T. P. P.; Freund, F.; Fumagalli, M.; Tellier, A.

10.1101/2022.09.28.508873 — genetics — Posted on 2022-09-30

155 Multifactorial heterogeneity of the human mutation landscape related to DNA replication dynamics

Caballero, M.; Boos, D. L.; Koren, A.

10.1101/2022.09.28.509938 — genetics — Posted on 2022-09-30

156 Detectability of runs of homozygosity is influenced by analysis parameters as well as population-specific demographic history

Harder, A. M.; Kirksey, K. B.; Mathur, S.; Willoughby, J. R.

10.1101/2022.09.29.510155 — evolutionary biology — Posted on 2022-09-30

157 Mutation and the Recombination Hotspot Paradox

Ubeda, F.; Fyon, F.; Buerger, R.

10.1101/2022.09.29.510084 — evolutionary biology — Posted on 2022-09-30

158 The contribution of mutation to variation in temperature-dependent sprint speed in zebrafish, Danio rerio

Miller, C. L.; Sun, D.; Thornton, L. H.; McGuigan, K.

10.1101/2022.09.28.509995 — evolutionary biology — Posted on 2022-09-30

159 The small-bat-in-summer paradigm: energetics and adaptive behavioural routines of bats investigated through a stochastic dynamic model

Fjelldal, M. A.; Muller, A. S.; Ratikainen, I. I.; Stawski, C.; Wright, J.

10.1101/2022.09.28.509895 — ecology — Posted on 2022-09-30

160 Wildflower phenological escape differs by continent and spring temperature

Lee, B. R.; Miller, T.; Rosche, C.; Yang, Y.; Heberling, J. M.; Kuebbing, S. E.; Primack, R. B.

10.1101/2022.09.28.509910 — ecology — Posted on 2022-09-30

161 Accelerated High-throughput Plant Imaging and Phenotyping System

Kose, T.; Lins, T. F.; Wang, J.; O'Brien, A. M.; Sinton, D.; Frederickson, M. E.

10.1101/2022.09.28.509964 — ecology — Posted on 2022-09-30

162 Unraveling the intricate microtubule inner protein networks that reinforce mammalian sperm flagella

Leung, M.; Roelofs, M.; Chiozzi, R. Z.; Hevler, J.; Heck, A.; Zeev-Ben-Mordehai, T.

10.1101/2022.09.29.510157 — cell biology — Posted on 2022-09-30

163 Modeling Microtubule-Cytoplasm Interaction in Plant Cells

Murshed, M.; Wei, D.; Gu, Y.; Wang, J.

10.1101/2022.09.29.510138 — cell biology — Posted on 2022-09-30

164 Role of intraflagellar transport in transcriptional control during flagellar regeneration in Chlamydomonas

Perlaza, K.; Zamora, I.; Marshall, W. F.

10.1101/2022.09.29.510156 — cell biology — Posted on 2022-09-30

165 Stress vesicles are induced by acute mechanical force and precede the commitment of epidermal stem cells to terminal differentiation

Huang, S.; Kuri, P.; Zou, J.; Blanco, A.; Marshall, M.; Rice, G.; Prouty, S.; Dentchev, T.; Doepner, M.; Boerckel, J. D.; Capell, B.; Ridky, T. W.; Rompolas, P.

10.1101/2022.09.29.510204 — cell biology — Posted on 2022-09-30

166 Nazo, the Drosophila homolog of the NBIA-mutated protein - c19orf12, is required for triglyceride homeostasis

Sreejith, P.; Lolo, S.; Patten, K. R.; Gunasinghe, M.; More, N.; Pallanck, L. J.; Bharadwaj, R.

10.1101/2022.09.29.510106 — cell biology — Posted on 2022-09-30

167 mTOR inhibitor-independent Autophagy Activator Ameliorates Cellular Tauopathy and Prionopathy Neurodegeneration Phenotypes

Yoon, L.; Botham, R. C.; Verhelle, A.; Cole, C.; Tan, E. P.; Wu, Y.; Sanz-Martinez, P.; Xu, J.; Cuoco, C. A.; Chou, C. C.; Labra, S.; Elia, L. P.; Massey, L. A.; Lee, K.; Xiao, Q.; Kline, G. M.; Ta, A.; Ardejani, M. S.; Cano-Franco, S.; Lyang, N. J.; Hou, W. C.; Yu, A.; Fox, S.; Ko, Y.; Chen, W.; Wulkop-Gil, C.; Ibrahim, L. H.; Jiang, S.; Meneses, A.; Nelson, L. T.; Peng, H.; Lipton, S. A.; Bollong, M. J.; Hansen, M.; Morimoto, R. I.; Finley, D.; Petrassi, H. M.; Wiseman, R. L.; Powers, E. T.; Finkbeiner, S.; Garza, D.; Prado, M. A.; Dikic, I.; Frydman, J.; Johnson, K. A.; Silva, M. C.; Haggar

10.1101/2022.09.29.509997 — cell biology — Posted on 2022-09-30

168 Single-cell sequencing identifies novel atypical B cell subsets with distinct effector functions

Reyes, R. A.; Batugedara, G.; Dutta, P.; Reers, A.; Garza, R.; Ssewanyana, I.; Feeney, M. E.; Greenhouse, B.; Bol, S.; Bunnik, E. M.

10.1101/2022.09.28.509955 — immunology — Posted on 2022-09-30

169 Value-Based Neural Representations Predict Social Decision Preferences

Guassi Moreira, J. F.; Mendez Leal, A. S.; Waizman, Y. H.; Tashjian, S. M.; Galvan, A.; Silvers, J. A.

10.1101/2022.09.28.509596 — neuroscience — Posted on 2022-09-30

170 A Simple Model of Cortical Intraregional Metastability

Venkadesh, S.; Shaikh, A.; Shakeri, H.; Henry, T. R.; Barreto, E.; Van Horn, J. D.

10.1101/2022.09.28.509893 — neuroscience — Posted on 2022-09-30

171 Subpopulations of cancer-associated fibroblasts expressing fibroblast activation protein and podoplanin in non-small cell lung cancer are a predictor of poor clinical outcome

Mathieson, L.; Koppensteiner, L.; Pattle, S.; Dorward, D. A.; O'Connor, R.; Akram, A. R.

10.1101/2022.09.28.509919 — cancer biology — Posted on 2022-09-30

172 Activity in the human superior colliculus associated with reaching for tactile targets

Prabhu, N. G.; Himmelbach, M.

10.1101/2022.09.06.506707 — neuroscience — Posted on 2022-09-30

173 MINI-EX: Integrative inference of single-cell gene regulatory networks in plants

Ferrari, C.; Manosalva Perez, N.; Vandepoele, K.

10.1101/2022.07.01.498402 — bioinformatics — Posted on 2022-09-30

174 Fluid extraction from the left-right organizer uncovers mechanical properties needed for symmetry breaking

Sampaio, P.; Pestana, S.; Guerrero, A.; Telley, I. A.; Smith, D. J.; Lopes, S. S.

10.1101/2022.04.21.489023 — developmental biology — Posted on 2022-09-30

175 Long non-coding RNA Neat1 and paraspeckle components are translational regulators in hypoxia.

Godet, A.-C.; Roussel, E.; David, F.; Hantelys, F.; Morfoisse, F.; Alves, J.; Pujol, F.; Ader, I.; Bertrand, E.; Burlet-Schiltz, O.; Froment, C.; Henras, A.; Vitali, P.; Lacazette, E.; Tatin, F.; Garmy-Susini, B.; Prats, A.-C.

10.1101/2021.02.10.430272 — molecular biology — Posted on 2022-09-30

176 The effects of combined action observation and motor imagery on corticospinal excitability and movement outcomes: Two meta-analyses

Chye, S.; Chembila Valappil, A.; Wright, D. J.; Frank, C.; Shearer, D. A.; Tyler, C. J.; Diss, C. E.; Mian, O.; Tillin, N.; Bruton, A. M.

10.1101/2022.05.23.493106 — neuroscience — Posted on 2022-09-30

177 Mechanisms of human dynamic object recognition revealed by sequential deep neural networks

Sörensen, L. K. A.; Bohte, S. M.; De Jong, D.; Slagter, H. A.; Scholte, H. S.

10.1101/2022.04.06.487259 — neuroscience — Posted on 2022-09-30

178 Diets affect the age-dependent decline of associative learning in Caenorhabditis elegans

Higurashi, S.; Tsukada, S.; Aleogho, B. M.; Park, J. H.; Tanaka, M.; Nakano, S.; Mori, I.; Noma, K.

10.1101/2020.10.08.331256 — neuroscience — Posted on 2022-09-30

179 A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta

Carter, B.; Huang, P.; Liu, G.; Liang, Y.; Lin, P. J. C.; Peng, B.-H.; McKay, L.; Dimitrakakis, A.; Hsu, J.; Tat, V.; Saenkham-Huntsinger, P.; Chen, J.; Kaseke, C.; Gaiha, G. D.; Xu, Q.; Griffiths, A.; Tam, Y. K.; Tseng, C.-T. K.; Gifford, D. K.

10.1101/2022.09.23.509206 — immunology — Posted on 2022-09-30

180 Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines.

Sunna, S.; Bowen, C.; Zeng, H.; Rayaprolu, S.; Kumar, P.; Bagchi, P.; Guo, Q.; Duong, D. M.; Bitarafan, S.; Natu, A.; Wood, L.; Seyfried, N. T.; Rangaraju, S.

10.1101/2022.09.27.509765 — neuroscience — Posted on 2022-09-30

181 COVIDpro: Database for mining protein dysregulation in patients with COVID-19

Zhang, F.; Luna, A.; Tan, T.; Chen, Y.; Sander, C.; Guo, T.

10.1101/2022.09.27.509819 — systems biology — Posted on 2022-09-30

182 Molecular Dynamics Simulations of Ion Permeation in human NaV Channels

Alberini, G.; Paz, S. A.; Corradi, B.; Abrams, C.; Benfenati, F.; Maragliano, L.

10.1101/2022.09.29.509656 — biophysics — Posted on 2022-09-30

183 Learning with phenotypic similarity improves the prediction of functional effects of missense variants in voltage-gated sodium channels

Bosselmann, C. M.; Hedrich, U. B. S.; Lerche, H.; Pfeifer, N.

10.1101/2022.09.29.510111 — bioinformatics — Posted on 2022-09-30

184 AssemblyTron: Flexible automation of DNA assembly with Opentrons OT-2 lab robots

Bryant, J. A.; Kellinger, M.; Longmire, C.; Miller, R.; Wright, R. C.

10.1101/2022.09.29.510219 — synthetic biology — Posted on 2022-09-30

185 Structural and functional characterization of chloroplast ribulose-5-phosphate-3-epimerase from the model green microalga Chlamydomonas reinhardtii

Meloni, M.; Fanti, S.; Tedesco, D.; Gurrieri, L.; Trost, P.; Fermani, S.; Lemaire, S. D.; Zaffagnini, M.; Henri, J.

10.1101/2022.09.29.510120 — biochemistry — Posted on 2022-09-30

186 The sulfonylpiperazine MMV020291 prevents red blood cell invasion by the malaria parasite Plasmodium falciparum through interference with actin-1/profilin dynamics

Dans, M. G.; Piirainen, H.; Nguyen, W.; Khurana, S.; Mehra, S.; Razook, Z.; Das, S.; Parkyn Schneider, M.; Jonsdottir, T. K.; Gabriela, M.; Gancheva, M. R.; Tonkin, C. J.; Mollard, V.; Goodman, C. D.; McFadden, G. I.; Wilson, D. W.; Barry, A. E.; Crabb, B. S.; de Koning-Ward, T. F.; Sleebs, B. E.; Kursula, I.; Gilson, P. R.

10.1101/2022.09.29.510018 — molecular biology — Posted on 2022-09-30

187 SIRT1 regulates DNA damage signaling through the PP4phosphatase complex

Rasti, G.; Becker, M.; Vazquez, B. N.; Espinosa-Alcantud, M.; Fernandez-Duran, I.; Gamez-Garcia, A.; Gonzalez-Nieto, J.; Bosch-Presegue, L.; Marazuela-Duque, A.; Segura-Bayona, S.; Ianni, A.; Bech-Serra, J.-J.; Scher, M.; Serrano, L.; Shankavaram, U.; Erdjument-Bromage, H.; Tempst, P.; Reinberg, D.; Olivella, M.; Stracker, T.; de la Torre, C.; Vaquero, A.

10.1101/2022.09.29.510108 — molecular biology — Posted on 2022-09-30

188 Towards environmental detection, quantification, and molecular characterization of Anopheles stephensi and Aedes aegypti from larval breeding sites

Kristan, M.; Acford-Palmer, H.; Campos, M. O.; Collins, E.; Phelan, J.; Portwood, N.; Pelloquin, B.; Clarke, S.; Lines, J.; Clark, T. G.; Walker, T.; Campino, S. G.; Messenger, L. A.

10.1101/2022.09.29.510135 — molecular biology — Posted on 2022-09-30

189 Expanded diversity of tfdA harboring bacteria across the natural and built environment

White, A. M.; Gonzalez Vazquez, A.; McDaniel, E. A.; Peterson, B. D.; Koch, P. L.; Remucal, C. K.; McMahon, K. D.

10.1101/2022.09.28.509959 — microbiology — Posted on 2022-09-30

190 Characterisation of an Escherichia coli line that completely lacks ribonucleotide reduction yields insights into the evolution of obligate intracellularity.

Arras, S. D. M.; Sibaeva, N.; Catchpole, R. J.; Horinouchi, N.; Si, D.; Rickerby, A. M.; Deguchi, K.; Hibi, M.; Tanaka, K.; Takeuchi, M.; Ogawa, J.; Poole, A. M.

10.1101/2022.09.28.509999 — microbiology — Posted on 2022-09-30

191 Correlation analysis between drug resistance and virulence genes of carbapenem-resistant Acinetobacter baumannii In Western Guilin

Xiong, L.; Huang, X.; Chen, H.; Liu, Z.; Wang, D.; Zeng, G.; Mo, S.; Wei, C.

10.1101/2022.09.28.510023 — microbiology — Posted on 2022-09-30

192 The molecular mechanism for carbon catabolite repression of the chitin response in Vibrio cholerae

Green, V. E.; Klancher, C. A.; Yamamoto, S.; Dalia, A. B.

10.1101/2022.09.29.510174 — microbiology — Posted on 2022-09-30

193 Metatranscriptomic response of the wheat holobiont to decreasing soil water content

Pande, P. M.; Azarbad, H.; Tremblay, J.; St-Arnaud, M.; Yergeau, E.

10.1101/2022.09.29.510153 — microbiology — Posted on 2022-09-30

194 Induced mineralization in Escherichia coli biofilms: the key role of bacterial alkaline phosphatase

Zorzetto, L.; Scoppola, E.; Raguin, E.; Blank, K. G.; Fratzl, P.; Bidan, C. M.

10.1101/2022.09.29.509673 — microbiology — Posted on 2022-09-30

195 Maternal cortisol and psychological symptoms alter the breast milks microbiome composition

Deflorin, N.; Ehlert, U.; Amiel Castro, R.

10.1101/2022.09.28.509979 — microbiology — Posted on 2022-09-30

196 Pathway elucidation of pharmaceutical cucurbitacin IIa in Hemsleya chinensis and high-level production of precursor cucurbitadienol in engineered Saccharomyces cerevisiae and Nicotiana benthamiana

Hao, B.; Chen, G.; Guo, Z.-k.; Zhao, Y.; Shu, Y.-y.; Qiu, L.; Duan, S.-f.; Lin, Y.; He, S.-m.; Li, X.-b.; Feng, X.-L.; Xiang, G.-s.; Shi, Y.; Yang, S.-C.; Zhang, G.-H.

10.1101/2022.09.28.509966 — synthetic biology — Posted on 2022-09-30

197 In situ targeted mutagenesis of gut bacteria

Brodel, A. K.; Charpenay, L.; Galtier, M.; Fuche, F. J.; Terrasse, R.; Poquet, C.; Arraou, M.; Prevot, G.; Spadoni, D.; Hessel, E. M.; Fernandez-Rodriguez, J.; Duportet, X.; Bikard, D.

10.1101/2022.09.30.509847 — synthetic biology — Posted on 2022-09-30

198 Diversity, Equity, and Inclusion in the Melanoma Research Community

Portuallo, M. E.; Lu, D. Y.; Alicea, G. M.; Bolling, J.; Lee, R.; McQuade, J.; Warner, A. B.; Davies, M.; Weeraratna, A.; Villanueva, J.; Rebecca, V. W.

10.1101/2022.09.24.509278 — scientific communication and education — Posted on 2022-09-30

199 Structural insights into Frizzled assembly by acylated Wnt and Frizzled Connector domain

Chang, T.-H.; Hsieh, F.-L.; Harlos, K.; Jones, E. Y.

10.1101/2022.09.29.510206 — biochemistry — Posted on 2022-09-30

200 in vivo RNA structural probing of guanine and uracil nucleotides in yeast

Xiao, K.; Ghalei, H.; Khoshnevis, S.

10.1101/2022.09.29.510215 — biochemistry — Posted on 2022-09-30

201 Structural basis of Norrin recognition by Lgr4/5/6

Chang, T.-H.; Harlos, K.; Hsieh, F.-L.; Jones, E. Y.

10.1101/2022.09.29.510199 — biochemistry — Posted on 2022-09-30

202 Influence of metal cations on the viscoelastic properties of Escherichia coli biofilms

Sarlet, A.; Ruffine, V.; Blank, K. G.; Bidan, C. M.

10.1101/2022.09.29.510089 — biochemistry — Posted on 2022-09-30

203 Reduced Cdc14 phosphatase activity impairs septation, hyphal differentiation and pathogenesis and causes echinocandin hypersensitivity in Candida albicans

Milholland, K. L.; AbdelKhalek, A.; Baker, K. M.; Hoda, S.; DeMarco, A. G.; Naughton, N. H.; Koeberlein, A. N.; Lorenz, G. R.; Anandasothy, K.; Esperilla-Munoz, A.; Narayanan, S. K.; Correa-Bordes, J.; Briggs, S. D.; Hall, M. C.

10.1101/2022.09.29.510203 — molecular biology — Posted on 2022-09-30

204 Single-nucleus RNA-seq reveals that MBD5, MBD6, and SILENZIO maintain silencing during epigenetic reprogramming in pollen

Ichino, L.; Picard, C. L.; Yun, J.; Chotai, M.; Wang, S.; Lin, E. K.; Papareddy, R. K.; Xue, Y.; Jacobsen, S. E.

10.1101/2022.09.29.510154 — molecular biology — Posted on 2022-09-30

205 Microbiota-dependent histone butyrylation in the mammalian intestine

Gates, L. A.; Reis, B. S.; Lund, P. J.; Paul, M. R.; Leboeuf, M.; Nadeem, Z.; Carroll, T. S.; Garcia, B.; Mucida, D.; Allis, C. D.

10.1101/2022.09.29.510184 — molecular biology — Posted on 2022-09-30

206 Early season soil microbiome best predicts wheat grain quality

Asad, N. I.; Wang, X.; Dozois, J. A.; Azarbad, H.; Constant, P.; Yergeau, E.

10.1101/2022.09.29.510160 — microbiology — Posted on 2022-09-30

207 A coordinated transcriptional switching network mediates antigenic variation of human malaria parasites

Zhang, X.; Florini, F.; Visone, J. E.; Leonardi, I.; Gross, M. R.; Patel, V.; Deitsch, K. W.

10.1101/2022.09.29.510131 — microbiology — Posted on 2022-09-30

208 Predicting enzyme substrate chemical structure with protein language models

Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Rappoport, D.; Rhee, K. Y.

10.1101/2022.09.28.509940 — microbiology — Posted on 2022-09-30

209 Production of selenium nanoparticles occurs through an interconnected pathway of sulfur metabolism and oxidative stress response in Pseudomonas putida KT2440

Avendano, R.; Munoz-Montero, S.; Rojas-Gätjens, D.; Fuentes, P.; Vieto, S.; Montenegro, R.; Salvador, M.; Frew, R.; Kim, J.; Chavarria, M.; Jimenez, J. I.

10.1101/2022.09.29.507446 — microbiology — Posted on 2022-09-30

210 Modulation of the functional interfaces between retroviral intasomes and the human nucleosome

Mauro, E.; Lapaillerie, D.; Tumiotto, C.; Charlier, C.; Martins, F.; Sousa, S.; Metifiot, M.; Weigel, P.; Yamatsugu, K.; Kanai, M.; Lehmann, H.; Richetta, C.; Batisse, J.; Ruff, M.; Delelis, O.; Paul, L.; Parissi, V.

10.1101/2022.09.29.510092 — microbiology — Posted on 2022-09-30

211 The paradoxical relationship between CRISPR-Cas and phage susceptibility in Pseudomonas aeruginosa

Lood, C.; Verkinderen, E.; Petrovic Fabijan, A.; Iredell, J. R.; Ceyssens, P.-J.; van Noort, V.; Lavigne, R.

10.1101/2022.09.29.510058 — microbiology — Posted on 2022-09-30

212 Exploring dose-response relationships in Aedes aegypti survival upon bacteria and arbovirus infection.

Rocha, M. M.; Talyuli, O. A. C.; Costa, C. L. R.; Granella, L. W.; Mansur, D. S.; Oliveira, P. L.; Oliveira, J. H. M.

10.1101/2022.09.29.510144 — microbiology — Posted on 2022-09-30

213 Atmospheric nitrogen fixation by eukaryotes: Should we reconsider the nitrogen cycle in nature?

Arapitsas, N.; Christakis, C. A.; Angelakis, G.; Maragkoudakis, A.; Kotzabasis, K.; Sarris, P. F.

10.1101/2022.09.29.510055 — microbiology — Posted on 2022-09-30

214 Mycelial differentiation linked avermectin production in studied with Raman imaging

Horii, S.; Samuel, A. Z.; Nakashima, T.; Take, A.; Matsumoto, A.; Takahashi, Y.; Ando, M.; Takeyama, H.

10.1101/2022.09.30.508653 — microbiology — Posted on 2022-09-30

215 Not getting in too deep: a practical deep learning approach to routine crystallisation image classification

Wilson, J.; Milne, J.; Qian, C.; Hargreaves, D.; Wang, Y.

10.1101/2022.09.28.509868 — molecular biology — Posted on 2022-09-30

216 Sequence-independent substrate selection by the eukaryotic wobble base deaminase ADAT2/3 involves multiple protein domains and distortion of the tRNA anticodon loop

Dolce, L. G.; Zimmer, A. A.; Tengo, L.; Weis, F.; Rubio, M. A. T.; Alfonzo, J. D.; Kowalinski, E.

10.1101/2022.06.16.496122 — molecular biology — Posted on 2022-09-30

217 Loss of Rab8a in B cells leads to increased antibody responses and class-switch recombination

Hernandez-Perez, S.; Sarapulov, A. V.; Balci, M. O.; Coffey, E.; Harada, A.; Mattila, P.

10.1101/2022.09.19.508414 — immunology — Posted on 2022-09-30

218 The Mechanisms Underlying Colour Afterimages

Witzel, C.

10.1101/2022.09.22.508985 — neuroscience — Posted on 2022-09-30

219 Cortical magnification underlies differences across but not around the visual field

Jigo, M.; Tavdy, D.; Carrasco, M.

10.1101/2022.04.27.489757 — neuroscience — Posted on 2022-09-30

220 Natural statistics support a rational account of confidence biases

Webb, T. W.; Miyoshi, K.; So, T. Y.; Rajananda, S.; Lau, H.

10.1101/2021.09.28.462081 — neuroscience — Posted on 2022-09-30

221 AGO1 and HSP90 buffer different genetic variants in Arabidopsis thaliana

Lemus, T.; Mason, G. A.; Bubb, K. L.; Alexandre, C. M.; Queitsch, C.; Cuperus, J. T.

10.1101/2022.06.27.497824 — plant biology — Posted on 2022-09-30

222 hERG1 channel subunit composition mediates proton inhibition of IKr in hiPSC CMs

Ukachukwu, C. U.; Jimenez-Vazquez, E. N.; Jain, A.; Jones, D. K.

10.1101/2022.08.26.505466 — physiology — Posted on 2022-09-30

223 Loss of FBXO11 function establishes a stem cell program in acute myeloid leukemia through dysregulation of the mitochondrial protease LONP1

Mo, A. Y.-C.; Kincross, H.; Wang, X.; Chang, L. Y.-T.; Duns, G.; Kwan, H.; Lau, T.; Docking, T. R.; Tran, J.; Colborne, S.; Cheng, S.-W. G.; Huang, S.; Gharaee, N.; Willie, E.; Jiang, J.; Parker, J.; Bridgers, J.; Wood, D.; Klein Geltink, R.; Morin, G. B.; Karsan, A.

10.1101/2022.09.10.507366 — cancer biology — Posted on 2022-09-30

224 Clomipramine inhibits dynamin GTPase activity by L-α-phosphatidyl-L-serine stimulation

Miyoshi, H.; Otomo, M.; Takahashi, K.

10.1101/2022.09.09.507370 — biochemistry — Posted on 2022-09-30

225 Frequent spontaneous structural rearrangements promote rapid genome diversification in a Brassica napus F1 generation

Orantes-Bonilla, M.; Makhoul, M.; Lee, H.; Singh Chawla, H.; Vollrath, P.; Langstroff, A.; Sedlazeck, F. J.; Zou, J.; Snowdon, R. J.

10.1101/2022.06.27.497715 — genomics — Posted on 2022-09-30

226 Primate sympatry shapes the evolution of their brain architecture

Robira, B.; Perez-Lamarque, B.

10.1101/2022.05.09.490912 — ecology — Posted on 2022-09-30

227 A novel method for monitoring ground-dwelling arthropods on hard substrates: characterizing arthropod biodiversity among survey methods

McNamara Manning, K.; Perry, K. I.; Bahlai, C.

10.1101/2021.12.06.471448 — ecology — Posted on 2022-09-30

228 Laboratory evolution of flies to morphogen dosage via rapid maternal changes reveals predictable outcomes

Li, X. C.; Gandara, L.; Ekelof, M.; Richter, K.; Alexandrov, T.; Crocker, J.

10.1101/2022.09.28.509860 — developmental biology — Posted on 2022-09-30

229 A human fetal lung cell atlas uncovers proximal-distal gradients of differentiation and key regulators of epithelial fates

He, P.; Lim, K.; Sun, D.; Pett, J. P.; Jeng, Q.; Polanski, K.; Dong, Z.; Bolt, L.; Richardson, L.; Mamanova, L.; Dabrowska, M.; Wilbrey-Clark, A. L.; Madissoon, E.; Tuong, K. Z.; Dann, E.; Suo, C.; Goh, I.; Yoshida, M.; Nikolic, M. Z.; James, S. M.; He, X.; Barker, R. A.; Teichmann, S.; Marioni, J.; Meyer, K. B.; Rawlins, E. L.

10.1101/2022.01.11.474933 — developmental biology — Posted on 2022-09-30

230 MR1 dependent MAIT cell activation is regulated by autophagy associated proteins

Phalora, P.; Ussher, J. E.; Hester, S.; Marchi, E.; Mak, J. Y. W.; Fairlie, D. P.; Klenerman, P.

10.1101/2022.09.20.508788 — cell biology — Posted on 2022-09-30

231 HIV-induced membraneless organelles orchestrate post-nuclear entry steps.

Scoca, V.; Morin, R.; Collard, M.; Tinevez, J.-Y.; Di Nunzio, F.

10.1101/2020.11.17.385567 — microbiology — Posted on 2022-09-30

232 A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

dos Reis, T. F.; de Castro, P. A.; Bastos, R.; Pinzan, C. F.; Souza, P. F.; Ackloo, S.; Hossain, M. A.; Drewry, D.; Alkhazraji, S.; Ibrahim, A.; Jo, H.; deGrado, W. F.; Goldman, G.

10.1101/2022.09.28.509882 — microbiology — Posted on 2022-09-30

233 Host cell amplification of nutritional stress contributes to persistence in Chlamydia trachomatis

Pokorzynski, N. D.; Alla, M. R.; CARABEO, R.

10.1101/2021.08.14.456350 — microbiology — Posted on 2022-09-30

234 AAV-delivered gene editing for latent genital or orofacial herpes simplex virus infection reduces ganglionic viral load and minimizes subsequent viral shedding in mice

Aubert, M.; Haick, A. K.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Huang, M.-l.; Hyrien, O.; Stone, D.; Jerome, K. R.

10.1101/2022.09.23.509057 — neuroscience — Posted on 2022-09-30

235 Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric gait

Lu, Y.; Ahamed, T.; Mulcahy, B.; Witvliet, D.; Guan, S. A.; Holmyard, D.; Hung, W.; Meng, J.; Wen, Q.; Chisholm, A.; Samuel, A.; Zhen, M.

10.1101/2021.09.21.461278 — neuroscience — Posted on 2022-09-30

236 Spontaneously emerging internal models of visual sequences combine abstract and event-specific information in the prefrontal cortex

Bellet, M. E.; Gay, M.; Bellet, J.; Jarraya, B.; Dehaene, S.; van Kerkoerle, T.; Panagiotaropoulos, T. I.

10.1101/2021.10.04.463064 — neuroscience — Posted on 2022-09-30

237 Insightful inference compensates for distorted perception

Mihali, A. L.; Broeker, M. D.; Ragalmuto, F.; Horga, G.

10.1101/2021.11.13.468497 — neuroscience — Posted on 2022-09-30

238 Computation of transcranial magnetic stimulation electric fields using self-supervised deep learning

Li, H.; Deng, Z.-D.; Oathes, D.; Fan, Y.

10.1101/2021.11.09.467946 — neuroscience — Posted on 2022-09-30

239 Antisense oligonucleotides targeting the miR-29b binding site in the GRN mRNA increase progranulin translation

Aggarwal, G.; Banerjee, S.; Jones, S. A.; Benchaar, Y.; Belanger, J.; Sevigny, M.; Smith, D. M.; Niehoff, M. L.; Pavlack, M. D.; de Vera, I. M. S.; Petkau, T. L.; Leavitt, B. R.; Ling, K.; Jafar-Nejad, P.; Rigo, F. D.; Morley, J. E.; Farr, S. A.; Dutchak, P. A.; Sephton, C. F.; Nguyen, A. D.

10.1101/2022.01.12.476053 — neuroscience — Posted on 2022-09-30

240 A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts

Kumbier, K.; Roth, M.; Li, Z.; Lazzari-Dean, J.; Waters, C.; Huang, P.; Korobeynikov, V.; ALS Consortium, N. Y. G. C.; Phatnani, H.; Shneider, N.; Jacobson, M. P.; Wu, L.; Altschuler, S.

10.1101/2022.09.27.509770 — systems biology — Posted on 2022-09-30

241 TMEM100, a Lung-Specific Endothelium Gene

Liu, B.; Yi, D.; Yu, Z.; Pan, J.; Ramirez, K.; Li, S.; Wang, T.; Glembotski, C.; Fallon, M.; Oh, P.; Gu, M.; Kalucka, J.; Dai, Z.

10.1101/2022.08.26.504609 — physiology — Posted on 2022-09-30

242 Dehydration alters transcript levels in the mosquito midgut, likely facilitating rapid rehydration

Holmes, C. J.; Brown, E. S.; Sharma, D.; Warden, M.; Pathak, A.; Payton, B.; Nguyen, Q.; Spangler, A.; Sivakumar, J.; Hendershot, J. M.; Benoit, J. B.

10.1101/2022.09.15.508146 — physiology — Posted on 2022-09-30

243 The long-term effects of repeated heroin vapor inhalation during adolescence on measures of nociception and anxiety-like behavior in adult Wistar rats

Gutierrez, A.; Harvey, E. L.; Creehan, K. M.; Taffe, M. A.

10.1101/2021.10.06.463404 — pharmacology and toxicology — Posted on 2022-09-30

244 The biomechanical context influences the PI3K output sig-naling in breast and pancreatic cancer cells.

Di-Luoffo, M.; Schmitter, C.; Barrere, E.; Therville, N.; Delarue, M.; Guillermet-Guibert, J.

10.1101/2021.10.18.464825 — cancer biology — Posted on 2022-09-30

245 IRF7 impacts on prostate cancer cell survival in response to radiation

Pickard, A.; Amoroso, F.; McCulloch, K.; Erickson, A.; Sachdeva, A.; Steele, R.; Mukherjee, D.; Dellett, M.; McComb, J.; McCaffrey, L.; Hart, C.; Brown, M.; McDade, S. S.; Waugh, D.; Clarke, N.; Butterworth, K.; Illidge, T.; Mirtti, T.; Overton, I. M.; Mills, I.

10.1101/2022.09.23.509205 — cancer biology — Posted on 2022-09-30

246 Phenotyping Polarization Dynamics Of Immune Cells Using A Lipid Droplet - Cell Pairing Microfluidic Platform

Pinon, L.; Ruyssen, N.; Pineau, J.; Mesdjian, O.; Cuvelier, D.; Chipont, A.; Allena, R.; Guerin, C.; Asnacios, S.; Asnacios, A.; Pierobon, P.; Fattaccioli, J.

10.1101/2021.12.22.473360 — biophysics — Posted on 2022-09-30

247 Parchment Glutamine Index (PQI): A novel method to estimate glutamine deamidation levels in parchment collagen obtained from low-quality MALDI-TOF data

Nair, B.; Palomo, I. R.; Markussen, B.; Wiuf, C.; Fiddyment, S.; Collins, M. J.

10.1101/2022.03.13.483627 — bioinformatics — Posted on 2022-09-30

248 Reconstructing the evolutionary history of a B cell lineage with minimum spanning tree and genotype abundances

Abdollahi, N.; Jeusset, L.; de Septenville, A.; Davi, F.; Bernardes, J. S.

10.1101/2022.02.27.481992 — bioinformatics — Posted on 2022-09-30

249 FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells

Warren, I. T.; Guiggey, D.; Chiang, A.; Maloy, M. H.; Ogoke, O.; Groth, T. S.; Mon, T.; Meamardoost, S.; Liu, X.; Thompson, S.; Szeglowski, A.; Thompson, R.; Chen, P.; Paulmurugan, R.; Yarmush, M. L.; Kidambi, S.; Parashurama, N.

10.1101/2020.06.01.128108 — bioengineering — Posted on 2022-09-30

250 Computational investigation of IP3 diffusion

Ornelas Guevara, R.; Gil, D.; Voorsluijs, V.; Dupont, G.

10.1101/2022.08.19.504488 — biochemistry — Posted on 2022-09-30

251 Dosage sensitivity in Pumilio1-related phenotypes reflects distinct disease mechanisms

Botta, S.; de Prisco, N.; Chemiakine, A.; Cabaj, M.; Patel, P.; Doron-Mandel, E.; Treadway, C. J.; Jovanovic, M.; Brown, N. G.; Soni, R. K.; Gennarino, V. A.

10.1101/2021.03.11.435015 — genetics — Posted on 2022-09-30

252 Genetic Regulators of Sputum Mucin Concentration and Their Associations with COPD Phenotypes

Van Buren, E.; Radicioni, G.; Lester, S.; O'Neal, W.; Dang, H.; Kasela, S.; Gardadri, S.; Curtis, J.; Han, M.; Krishnan, J.; Wan, E.; Silverman, E.; Hastie, A.; Ortega, V.; Lappalainen, T.; Christenson, S.; Li, Y.; Cho, M.; Kesimer, M.; Kelada, S.

10.1101/2022.09.28.509838 — genetics — Posted on 2022-09-30

253 Positive selection of senescence through increased evolvability: ageing is not a by-product of evolution.

Roget, T.; Jolivet, P.; Meleard, S.; Rera, M.

10.1101/2022.03.11.483978 — evolutionary biology — Posted on 2022-09-30

254 Restrained activation of CYFIP2-containing WAVE complexes controls membrane protrusions and cell migration

Polesskaya, A.; Boutillon, A.; Yang, S.; Wang, Y.; Romero, S.; Liu, Y.; Lavielle, M.; Molinie, N.; Rocques, N.; Fokin, A.; Guerois, R.; Chen, B.; David, N. B.; Gautreau, A. M.

10.1101/2020.07.02.184655 — cell biology — Posted on 2022-09-30

255 Extracellular caspase-1 regulates hair follicle stem cell migration during wound-healing

Ghosh, S.; Hegde, A.; Ananthan, A. S.; Kataria, S.; Pincha, N.; Dutta, A.; Dutta, A.; Athreya, S.; Khedkar, S. U.; Dey, R.; Bhosale, A.; Jamora, C.

10.1101/548529 — cell biology — Posted on 2022-09-30

256 Posterodorsal medial amygdala urocortin-3, GABA and glutamate mediate suppression of LH pulsatility in female mice

Ivanova, D.; Li, X.; McIntyre, C.; O'Byrne, K.

10.1101/2022.07.07.499104 — neuroscience — Posted on 2022-09-30

257 Midbrain-Hippocampus Structural Connectivity Selectively Predicts Motivated Memory Encoding

Elliott, B. L.; D'Ardenne, K.; Murty, V. P.; Brewer, G. A.; McClure, S. M.

10.1101/2022.05.18.492387 — neuroscience — Posted on 2022-09-30

258 Intelligibility improves perception of timing changes in speech

Zoefel, B.; Gilbert, R. A.; Davis, M. H.

10.1101/2022.05.18.492430 — neuroscience — Posted on 2022-09-30

259 EPAC1 Inhibition Protects the Heart from Doxorubicin-Induced Toxicity

Mazevet, M.; Belhadef, A.; Ribeiro, M.; Dayde, D.; Llach, A.; Laudette, M.; Belleville, T.; Mateo, P.; Gressette, M.; Lefebvre, F.; Chen, J.; Bachelot-Loza, C.; Rucker-Martin, C.; Lezoualch, F.; Crozatier, B.; Benitah, J.-P.; Vozenin, M.-C.; Fischmeister, R.; Gomez, A.-M.; Lemaire, C.; Morel, E.

10.1101/2021.06.16.448655 — pathology — Posted on 2022-09-30

260 Moving beyond MARCO

Rosa, N.; Watkins, C. J.; Newman, J. M.

10.1101/2022.09.28.509867 — biophysics — Posted on 2022-09-30

261 Polygenic scoring accuracy varies across the genetic ancestry continuum in all human populations

Ding, Y.; Hou, K.; Xu, Z.; Pimplaskar, A.; Petter, E.; Boulier, K.; Prive, F.; Vilhjalmsson, B. J.; Loohuis, L. O.; Pasaniuc, B.

10.1101/2022.09.28.509988 — genetics — Posted on 2022-09-29

262 Semantic reconstruction of continuous language from non-invasive brain recordings

Tang, J.; LeBel, A.; Jain, S.; Huth, A. G.

10.1101/2022.09.29.509744 — neuroscience — Posted on 2022-09-29

263 Development shaped by cue reliability in the barn owl's auditory midbrain

Shadron, K. K.; Pena, J. L.

10.1101/2022.09.29.510116 — neuroscience — Posted on 2022-09-29

264 Analysis of proteome adaptation reveals a key role of the bacterial envelope in starvation survival

Schink, S. J.; Ammar, C.; Chang, Y.-F.; Zimmer, R.; Basan, M.

10.1101/2022.05.18.492425 — systems biology — Posted on 2022-09-29

265 Sharing GWAS summary statistics results in more citations: evidence from the GWAS catalog

Reales, G.; Wallace, C.

10.1101/2022.09.27.509657 — genomics — Posted on 2022-09-29

266 Accurate and efficient constrained molecular dynamics of polymers through Newton's method and special purpose code

Lopez-Villellas, L.; Kjelgaard Mikkelsen, C. C.; Galano-Frutos, J. J.; Marco-Sola, S.; Alastruey-Benede, J.; Ibanez, P.; Moreto, M.; Sancho, J.; Garcia-Risueno, P.

10.1101/2022.09.28.509839 — molecular biology — Posted on 2022-09-29

267 ROS are evolutionary conserved cell-to-cell signals

Fichman, Y.; Rowland, L.; Oliver, M.; Mittler, R.

10.1101/2022.08.19.504606 — plant biology — Posted on 2022-09-29

268 Single molecule imaging and modelling of mRNA decay dynamics in the Drosophila embryo

Forbes Beadle, L.; Love, J. C.; Shapovalova, Y.; Artemev, A.; Rattray, M.; Ashe, H. L.

10.1101/2022.03.17.484585 — developmental biology — Posted on 2022-09-29

269 Sensitivity of diffusion-tensor and correlated diffusion imaging to white-matter microstructural abnormalities: application in COVID-19

Teller, N.; Chad, J. A.; Wong, A.; Gunraj, H.; Ji, X.; MacIntosh, B. J.; Roudaia, E.; Gilboa, A.; Lam, B.; Sekuler, A.; Heyn, C.; Graham, S.; Black, S.; Chen, J. J.

10.1101/2022.09.29.510004 — biophysics — Posted on 2022-09-29

270 A linear SARS-CoV-2 DNA vaccine candidate reduces virus shedding in ferrets

Martins, M.; do Nascimento, G. M.; Conforti, A.; Noll, J. C. G.; Impellizeri, J. A.; Sanches, E.; Wagner, B.; Lione, L.; Salvatori, E.; Pinto, E.; Compagnone, M.; Viscount, B.; Hayward, J.; Shorrock, C.; Aurisicchio, L.; Diel, D. G.

10.1101/2022.09.29.510112 — immunology — Posted on 2022-09-29

271 Rich dynamics and functional organization on topographically designed neuronal networks in vitro

Montala-Flaquer, M.; Lopez-Leon, C. F.; Tornero, D.; Houben, A. M.; Fardet, T.; Monceau, P.; Bottani, S.; Soriano, J.

10.1101/2022.09.28.509646 — bioengineering — Posted on 2022-09-29

272 Integrated single-cell chromatin and transcriptomic analyses of human scalp reveal etiological insights into genetic risk for hair and skin disease

Ober-Reynolds, B.; Wang, C.; Ko, J. M.; Rios, E. J.; Aasi, S. Z.; Davis, M. M.; Oro, A. E.; Greenleaf, W. J.

10.1101/2022.09.28.509620 — genomics — Posted on 2022-09-29

273 Incorporating natural language into vision models improves prediction and understanding of higher visual cortex

Wang, A. Y.; Kay, K.; Naselaris, T.; Tarr, M. J.; Wehbe, L.

10.1101/2022.09.27.508760 — neuroscience — Posted on 2022-09-29

274 Cortical somatostatin interneuron subtypes form cell-type specific circuits

Wu, J. S.; Sevier, E.; Saldi, G.-A.; Yu, S.; Abbott, L.; Choi, D. H.; Sherer, M.; Qiu, Y.; Shinde, A.; Rizzo, D.; Xu, Q.; Barrera, I.; Kumar, V.; Marrero, G.; Pörnneke, A.; Huang, S.; Rudy, B.; Stafford, D. A.; Macosko, E.; Chen, F.; Fishell, G.

10.1101/2022.09.29.510081 — neuroscience — Posted on 2022-09-29

275 Stability of a biomembrane tube covered with proteins

Janssen, M.; liese, s.; Carlson, A.

10.1101/2022.09.29.510025 — biophysics — Posted on 2022-09-29

276 Meta-analysis refinement of plasma extracellular vesicle composition identifies proplatelet basic protein as a signaling messenger in type 1 diabetes

Vallejo, M. C.; Sarkar, S.; Elliott, E. C.; Henry, H. R.; Huang, F.; Payne, S. H.; Ramanadham, S.; Sims, E. K.; Metz, T. O.; Mirmira, R.; Nakayasu, E. S.

10.1101/2022.09.28.509996 — cell biology — Posted on 2022-09-29

277 USP22 overexpression fails to augment tumor formation in MMTV-ERBB2 mice but loss of function impacts MMTV promoter activity

Kuang, X.; Salinger, A.; Benavides, F. J.; Muller, W. J.; Dent, S. Y.; Koutelou, E.

10.1101/2022.09.28.510017 — cancer biology — Posted on 2022-09-29

278 A grappling hook interaction balances self-assembly and chaperone activity of Nucleophosmin 1

Saluri, M.; Leppert, A.; Gese, G. V.; Sahin, C.; Lama, D.; Kaldmae, M.; Chen, G.; Elofsson, A.; Allison, T. M.; Arsenian-Henriksson, M.; Lane, D. P.; Johansson, J.; Hallberg, B. M.; Landreh, M.

10.1101/2022.09.29.510028 — biophysics — Posted on 2022-09-29

279 De novo protein identification in mammalian sperm using high-resolution in situ cryo-electron tomography

Chen, Z.; Shiozaki, M.; Haas, K. M.; Zhao, S.; Guo, C.; Polacco, B. J.; Yu, Z.; Krogan, N. J.; Kaake, R. M.; Vale, R. D.; Agard, D. A.

10.1101/2022.09.28.510016 — biophysics — Posted on 2022-09-29

280 Divergent expression of aristaless1 and aristaless2 is associated with embryonic appendage and pupal wing development in butterflies

Bayala, E. X.; Cisneros, I.; Massardo, D.; VanKuren, N. W.; Kronforst, M. R.

10.1101/2022.09.28.509918 — developmental biology — Posted on 2022-09-29

281 The generation of the first chromosome-level de-novo genome assembly and the development and validation of a 50K SNP array for North American Atlantic salmon

Gao, G.; Waldbieser, G. C.; Youngblood, R. C.; Zhao, D.; Pietrak, M.; Allen, M.; Stannard, J.; Buchanan, J.; Long, R.; Milligan, M.; Burr, G.; Mejia-Guerra, K.; Sheehan, M.; Scheffler, B. E.; Rexroad, C.; Peterson, B.; Palti, Y.

10.1101/2022.09.28.509896 — genomics — Posted on 2022-09-29

282 TGFβ-induced long non-coding RNA LINC00313 activates Wnt signaling and promotes cholangiocarcinoma

Papoutsoglou, P.; Louis, C.; Pineau, R.; L'Haridon, A.; Banales, J. M.; Gilot, D.; Aubry, M.; Coulouarn, C.

10.1101/2022.09.28.509889 — cancer biology — Posted on 2022-09-29

283 Exosome-derived lncRNA HOXA-AS3 promotes castration resistance and progression of prostate cancer via the miR-29b-3p/Mcl-1/STAT3 axis

Jie, T.; Cai, Q.; Zhao, Y.; Shang, L.; Li, Y.; Zhang, J.; Zhu, L.; Chen, Y.; Li, G.; Liu, Z.; Jia, M.; Kang, S.; Niu, H.; Niu, Y.

10.1101/2022.09.28.509879 — genomics — Posted on 2022-09-29

284 svep1 and tie1 genetically interact and affect aspects of facial lymphatic development in a Vegfc-independent manner

Hussmann, M.; Weischer, S.; Carlantoni, C.; Stainier, D. Y.; Zobel, T.; Schulte-Merker, S.

10.1101/2022.09.28.509871 — developmental biology — Posted on 2022-09-29

285 Laboratory evolution of flies to morphogen dosage via rapid maternal changes reveals predictable outcomes

Li, X. C.; Gandara, L.; Ekelöf, M.; Richter, K.; Alexandrov, T.; Crocker, J.

10.1101/2022.09.28.509860 — developmental biology — Posted on 2022-09-29

286 Investigation of the genus Flavobacterium as a reservoir for fish-pathogenic bacterial species: the case of Flavobacterium collinsii

Duchaud, E.; Lee, B.-H.; Nicolas, P.; Saticioglu, I. B.; Fradet, B.; Bernardet, J.-F.; Rigaudeau, D.; Rochat, T.

10.1101/2022.09.27.509832 — microbiology — Posted on 2022-09-29

287 The Arabidopsis SHORTROOT network coordinates shoot apical meristem development with auxin dependent lateral organ initiation

Bahafid, E.; Bradtmöller, I.; Thies, A. M.; Nguyen, T. T. O. N.; Gutierrez, C.; Desvoyes, B.; Stahl, Y.; Blilou, I.; Simon, R. G.

10.1101/2022.09.27.509828 — plant biology — Posted on 2022-09-29

288 Abnormal intrinsic neural timescale in Parkinson's disease

Wei, Y.; Zhang, C.; Peng, Y.; Chen, C.; Han, S.; Wang, W.; Zhang, Y.; Lu, H.; Cheng, J.

10.1101/2022.09.17.508074 — neuroscience — Posted on 2022-09-29

289 Further Perceptions of Probability: In Defence of Associative Models -- A Commentary on Gallistel et al. 2014

Forsgren, M.; Juslin, P.; van den Berg, R.

10.1101/2020.01.30.927558 — animal behavior and cognition — Posted on 2022-09-29

290 36-year study reveals the effects of microhabitats on a wild wheat population

Dahan-Meir, T.; Ellis, T. J.; Mafessoni, F.; Sela, H.; Rudich, O.; Manisterski, J.; Avivi-Ragolsky, N.; Raz, A.; Feldman, M.; Anikster, Y.; Nordborg, M.; Levy, A. A.

10.1101/2022.01.10.475641 — evolutionary biology — Posted on 2022-09-29

291 Toward a first principles understanding of the activation and deactivation mechanisms of class A G-protein coupled receptors and voltage-gated cation channels

Wan, H.; Pearlstein, R. A.

10.1101/2022.03.29.486149 — pharmacology and toxicology — Posted on 2022-09-28

292 Where the Minor Things Are: A Survey of Minor Spliceosomal Introns in Thousands of Eukaryotic Genomes

Larue, G. E.; Roy, S. W.

10.1101/2022.09.24.509304 — bioinformatics — Posted on 2022-09-29

293 Tubule jamming in the developing kidney creates cyclical mechanical stresses instructive to nephron formation

Viola, J. M.; Liu, J.; Prahl, L. S.; Huang, A.; Chan, T. J.; Hayward-Lara, G.; Porter, C. M.; Shi, C.; Zhang, J.; Hughes, A. J.

10.1101/2022.06.03.494718 — bioengineering — Posted on 2022-09-29

294 Genomic insights into the recent evolutionary adaptation of snapdragon and the origin of S-locus

Zhu, S.; Zhang, Y.; Copsey, L.; Zheng, D.; Coen, E.; Xue, Y.

10.1101/2022.07.17.500290 — genomics — Posted on 2022-09-28

295 A moonlighting function of Atg11 in spindle positioning

Reza, M. H.; Aggarwal, R.; Verma, J.; Chowdhury, R.; Manjithaya, R.; Sanyal, K.

10.1101/2021.12.15.472744 — genetics — Posted on 2022-09-28

296 Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex-dependent endocytosis

Bigge, B. M.; Rosenthal, N. E.; Avasthi, P.

10.1101/2020.11.24.396002 — cell biology — Posted on 2022-09-29

297 Active Translation Control of CD4 T Cell Activation by Regulatory T Cells

So, L.; Obata-Ninomiya, K.; Hu, A.; Muir, V.; Takamori, A.; Song, J.; Buckner, J. H.; Savan, R.; Ziegler, S.

10.1101/2021.09.23.461566 — immunology — Posted on 2022-09-28

298 Resolving inter-regional communication capacity in the human connectome

Milisav, F.; Bazinet, V.; Iturria-Medina, Y.; Misic, B.

10.1101/2022.09.28.509962 — neuroscience — Posted on 2022-09-28

299 Silicone Oil-Induced Glaucomatous Neurodegeneration in Rhesus Macaques

Moshiri, A.; Fang, F.; Zhuang, P.; Huang, H.; Feng, X.; Li, L.; Dalal, R.; Hu, Y.

10.1101/2022.06.06.494980 — neuroscience — Posted on 2022-09-29

300 Multiplexed 3D atlas of state transitions and immune interactions in colorectal cancer

Lin, J.-R.; Wang, S.; Coy, S.; Chen, Y.-A.; Yapp, C.; Tyler, M. A.; Nariya, M.; Heiser, C. N.; Lau, K.; Santagata, S.; Sorger, P. K.

10.1101/2021.03.31.437984 — cancer biology — Posted on 2022-09-28

301 Combined Scattering, Interferometric and Fluorescence Oblique Illumination for Live Cell Nanoscale Imaging

Zheng, Y.; Lim, Y. J.; Lin, H.; Xu, T.; Longbottom, C.; Delghingaro-Augusto, V.; Thong, Y. L.; Parish, C. R.; Gardiner, E. E.; Lee, W. M.

10.1101/2022.07.22.501104 — biophysics — Posted on 2022-09-28

302 Evaluating a Human/Machine Interface with Redundant Motor Modalities for Trajectory-Tracking

Chou, A. H. Y.; Yamagami, M.; Burden, S. A.

10.1101/2022.06.29.498180 — bioengineering — Posted on 2022-09-28

303 Synthetic regulatory genomics uncovers enhancer context dependence at the Sox2 locus

Brosh, R.; Coelho, C.; Ribeiro-dos-Santos, A. M.; Ellis, G.; Hogan, M. S.; Ashe, H. J.; Somogyi, N.; Ordonez, R.; Luther, R.; Huang, E.; Boeke, J. D.; Maurano, M. T.

10.1101/2022.06.20.495832 — genomics — Posted on 2022-09-28

304 Omnigenic epistasis regulates complex trait heritability

Miller, A. K.; Pan, C.; Lusis, A. J.; Crawford, D. C.; Williams, S. M.; Buchner, D. A.

10.1101/2022.09.28.509932 — genetics — Posted on 2022-09-28

305 Tropical hummingbird pollination networks are resistant to short-term experimental removal of a common flowering plant

Leimberger, K. G.; Hadley, A. S.; Frey, S. J. K.; Betts, M. G.

10.1101/2022.02.24.481682 — ecology — Posted on 2022-09-28

306 CTCF and R-loops are boundaries of cohesin-mediated DNA looping

Zhang, H.; Shi, Z.; Kim, Y.; Yu, H.; Bai, X.-c.; Finkelstein, I. J.

10.1101/2022.09.15.508177 — molecular biology — Posted on 2022-09-28

307 Interleukin-17 drives sex-dependent weight loss and changes in feeding behaviour during Trypanosoma brucei infection

Sinton, M. C.; Girard, A.; Ogunsola, J.; Chandrasegaran, P.; Capewell, P.; Perona-Wright, G.; Ngoyi, D.; Kuispond, N.; BUCHETON, B.; Camara, M.; Kajimura, S.; Benezech, C.; MacLeod, A.; Quintana Alcala, J. F.

10.1101/2022.09.23.509158 — immunology — Posted on 2022-09-28

308 Criticality of neuronal avalanches in human sleep and their relationship with sleep macro- and micro-architecture

Scarpetta, S.; Morrisi, N.; Mutti, C.; Azzi, N.; Trippi, I.; Ciliento, R.; Apicella, I.; Messuti, G.; Angiolelli, M.; Lombardi, F.; Parrino, L.; Vaudano, A. E.

10.1101/2022.07.12.499725 — neuroscience — Posted on 2022-09-28

309 Controlling periodic long-range signalling to drive a morphogenetic transition

Ford, H. Z.; Manhart, A.; Chubb, J. R.

10.1101/2022.01.07.475371 — biophysics — Posted on 2022-09-28

310 Automated image analysis method to detect and quantify fat cell infiltration in hematoxylin and eosin stained human pancreas histology images

Naik, R.; Rajan, A.; Kalita, N.

10.1101/2021.12.13.472341 — bioinformatics — Posted on 2022-09-28

311 LEVELNET to visualise, explore and compare protein-protein interaction networks

MOHSENI BEHBAHANI, Y.; SAIGHI, P.; CORSI, F.; LAINE, E.; CARBONE, A.

10.1101/2021.07.31.453756 — bioinformatics — Posted on 2022-09-28

312 How many sirtuin genes are out there? evolution of sirtuin genes in vertebrates with a description of a new family member

Opazo, J. C.; Vandewege, M.; Hoffmann, F. G.; Zavala, K.; Melendez, C.; Luchsinger, C.; Cavieres, V.; Vargas-Chacoff, L.; Morera, F.; Burgos, P.; Tapia-Rojas, C.; Mardones, G.

10.1101/2020.07.17.209510 — evolutionary biology — Posted on 2022-09-28

313 Trade-offs constrain adaptive pathways to T6 survival

MacGillivray, K. A.; Ng, S. L.; Wiesenfeld, S.; Guest, R. L.; Jubery, T.; Silhavy, T. J.; Ratcliff, W. C.; Hammer, B. K.

10.1101/2022.09.02.506412 — evolutionary biology — Posted on 2022-09-28

314 Machine-learning dissection of Human Accelerated Regions in primate neurodevelopment

Whalen, S.; Inoue, F.; Ryu, H.; Fair, T.; Markenscoff-Papadimitriou, E.; Keough, K.; Kircher, M.; Martin, B.; Alvarado, B.; Elor, O.; Cintron, D. L.; Williams, A.; Samee, M. A. H.; Thomas, S.; Krencik, R.; Ullian, E.; Kriegstein, A.; Shendure, J.; Pollen, A.; Ahituv, N.; Pollard, K. S.

10.1101/256313 — evolutionary biology — Posted on 2022-09-28

315 Correspondence Of Newcomb-Benford Number Law With Ecological Processes

Davic, R. D.

10.1101/2022.06.27.497806 — ecology — Posted on 2022-09-28

316 OnRamp: rapid nanopore plasmid validation

Mumm, C.; Drexel, M. L.; McDonald, T. L.; Diehl, A.; Switzenberg, J. A.; Boyle, A. P.

10.1101/2022.03.15.484480 — molecular biology — Posted on 2022-09-28

317 Automated hippocampal unfolding for morphometry and subfield segmentation with HippUnfold

DeKraker, J.; Haast, R. A.; Yousif, M. D.; Karat, B.; Lau, J. C.; Kohler, S.; Khan, A. R.

10.1101/2021.12.03.471134 — neuroscience — Posted on 2022-09-28

318 Flexible Sensory-Motor Mapping Rules Manifest in Correlated Variability of Stimulus and Action Codes Across the Brain

van den Brink, R. L.; Hagena, K.; Wilming, N.; Murphy, P. R.; Buechel, C.; Donner, T. H.

10.1101/2022.03.10.483758 — neuroscience — Posted on 2022-09-28

319 Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming.

Keine, C.; Al-Yaari, M.; Radulovic, T.; Thomas, C. I.; Valino Ramos, P.; Guerrero-Given, D.; Ranjan, M.; Taschenberger, H.; Kamasawa, N.; Young, S. M.

10.1101/2022.06.29.497712 — neuroscience — Posted on 2022-09-28

320 Efficient coding, channel capacity and the emergence of retinal mosaics

Jun, N. Y.; Field, G. D.; Pearson, J. M.

10.1101/2022.08.29.505726 — neuroscience — Posted on 2022-09-28

321 Intrinsic neural timescales in the temporal lobe support an auditory processing hierarchy

Cusinato, R.; Alnes, S. L.; van Maren, E.; Boccalaro, I.; Ledergerber, D.; Adamantidis, A.; Imbach, L. L.; Schindler, K.; Baud, M. O.; Tzovara, A.

10.1101/2022.09.27.509695 — neuroscience — Posted on 2022-09-28

322 TemplateFlow: FAIR-sharing of multi-scale, multi-species brain models

Ciric, R.; Thompson, W. H.; Lorenz, R.; Goncalves, M.; MacNicol, E.; Markiewicz, C.; Halchenko, Y.; Ghosh, S. S.; Gorgolewski, K. J.; Poldrack, R.; Esteban, O.

10.1101/2021.02.10.430678 — neuroscience — Posted on 2022-09-28

323 Faster detection of "darks" than "brights" by monkey superior colliculus neurons

Malevich, T.; Zhang, T.; Baumann, M. P.; Bogadhi, A. R.; Hafed, Z. M.

10.1101/2022.08.03.502615 — neuroscience — Posted on 2022-09-28

324 Task-uninformative visual stimuli improve auditory spatial discrimination: the ambiguous contribution of relative reliability

Cappelloni, M. S. S.; Shivkumar, S.; Haefner, R. M.; Maddox, R. K.

10.1101/2022.08.24.505112 — neuroscience — Posted on 2022-09-28

325 SpatialDM: Rapid identification of spatially co-expressed ligand-receptor reveals cell-cell communication patterns

LI, Z.; Wang, T.; Liu, P.; Huang, Y.

10.1101/2022.08.19.504616 — bioinformatics — Posted on 2022-09-28

326 Important anatomical, age-related, and species considerations regarding ocular fibulin-3 (EFEMP1) analysis

Daniel, S.; Hulleman, J.

10.1101/2022.09.28.509587 — neuroscience — Posted on 2022-09-28

327 COVIDpro: Database for mining protein dysregulation in patients with COVID-19

Zhang, F.; Luna, A.; Tan, T.; Chen, Y.; Sander, C.; Guo, T.

10.1101/2022.09.27.509819 — systems biology — Posted on 2022-09-28

328 Parallel evolution and cryptic diversification in the common and widespread Amazonian tree, Protium subserratum

Misiewicz, T. M.; Simmons, T.; Carter, B. E.; Fine, P. V.; Moore, A. J.

10.1101/2022.09.28.509925 — evolutionary biology — Posted on 2022-09-28

329 Bacteriophages targeting protective commensals impair resistance against Salmonella Typhimurium infection in gnotobiotic mice

von Strempel, A.; Weiss, A. S.; Wittmann, J.; Salvado Silva, M.; Ring, D.; Wortmann, E.; Clavel, T.; Debarbieux, L.; Kleigrewe, K.; Stecher, B.

10.1101/2022.09.28.509654 — microbiology — Posted on 2022-09-28

330 Nirmatrelvir-resistant SARS-CoV-2 is efficiently transmitted in Syrian hamsters

Abdelnabi, R.; Jochmans, D.; Donckers, K.; Trueeb, B.; Ebert, N.; Weynand, B.; Thiel, V.; Neyts, J.

10.1101/2022.09.28.509903 — microbiology — Posted on 2022-09-28

331 IgG3 subclass antibodies recognize antigenically drifted influenza viruses and SARS-CoV-2 variants through efficient bivalent binding

Bolton, M.; Arevalo, C. P.; Griesman, T.; Li, S. H.; Bates, P.; Wilson, P. C.; Hensley, S. E.

10.1101/2022.09.27.509738 — microbiology — Posted on 2022-09-28

332 Activation of SARS-CoV-2 by trypsin-like proteases in the clinical specimens of patients with COVID-19

Igarashi, E.; Shimada, T.; Yazawa, S.; Saga, Y.; Itamochi, M.; Inasaki, N.; Morinaga, Y.; Oishi, K.; Tani, H.

10.1101/2022.09.27.509803 — microbiology — Posted on 2022-09-28

333 Mutational spectra distinguish SARS-CoV-2 replication niches

Ruis, C.; Peacock, T. P.; Polo, L. M.; Masone, D.; Soledad Alvarez, M.; Hinrichs, A. S.; Turakhia, Y.; Ye, C.; McBroome, J.; Corbett-Detig, R.; Parkhill, J.; Floto, R. A.

10.1101/2022.09.27.509649 — microbiology — Posted on 2022-09-28

334 Synthetic carbon fixation via the autocatalytic serine threonine cycle

Wenk, S.; Rainaldi, V.; He, H.; Schann, K.; Bouzon, M.; Doering, V.; Lindner, S.; Bar-Even, A.

10.1101/2022.09.28.509898 — synthetic biology — Posted on 2022-09-28

335 TRAF6 modulates PD-L1 expression through YAP1-TFCP2 signaling in melanoma

Liu, X.; Wang, L.; Han, Y.; Tsai, H.-i.; Shu, F.; Xu, Z.; He, C.; Zhu, H.; Chen, H.; Cheng, F.

10.1101/2022.09.28.509909 — cancer biology — Posted on 2022-09-28

336 Uncovering the contributions of charge regulation to the stability of single alpha helices

Fossat, M. J.; Posey, A. E.; Pappu, R. V.

10.1101/2022.09.28.509894 — biophysics — Posted on 2022-09-28

337 Global proteome metastability response in isogenic animals to missense mutations and polyglutamine expansions in aging

Sui, X.; Prado, M. A.; Paulo, J. A.; Gygi, S. P.; Finley, D.; Morimoto, R. I.

10.1101/2022.09.28.509812 — biochemistry — Posted on 2022-09-28

338 DASH/Dam1 complex mutants stabilize ploidy by weakening kinetochore-microtubule attachments

Haase, M. A. B.; Olafsson, G.; Flores, R. L.; Boakye-Ansah, E.; Zelter, A.; Dickinson, M. S.; Stefanita, L. L.; Truong, D. M.; Asbury, C. L.; Davis, T. N.; Boeke, J. D.

10.1101/2022.09.28.509901 — genetics — Posted on 2022-09-28

339 Piezo1-mediated spontaneous activity of satellite glia impacts DRG development

Brandt, J. P.; Smith, C. J.

10.1101/2022.09.28.509897 — developmental biology — Posted on 2022-09-28

340 Inhibition of the ATM kinase rescues planarian regeneration after lethal radiation

Shiroor, D. A.; Wang, K.-T.; Sanketi, B. D.; Tapper, J. K.; Adler, C. E.

10.1101/2022.09.28.509579 — cell biology — Posted on 2022-09-28

341 Structural insights into TRAP association with ribosome-Sec61 complex, and translocon inhibition by a CADA derivative

Pauwels, E.; Shewakramani, N. R.; De Wijngaert, B.; Camps, A.; Provinciael, B.; Stroobants, J.; Kalies, K.-U.; Hartmann, E.; Maes, P.; Vermeire, K.; Das, K.

10.1101/2022.09.28.509949 — cell biology — Posted on 2022-09-28

342 HSV-1 infection induces a downstream shift of promoter-proximal pausing linked to H2A.Z-containing +1 nucleosomes

Weiss, E.; Hennig, T.; Grassl, P.; Djakovic, L.; Whisnant, A. W.; Juerges, C. S.; Koller, F.; Kluge, M.; Erhard, F.; Doelken, L.; Friedel, C. C.

10.1101/2022.09.28.509911 — molecular biology — Posted on 2022-09-28

343 A host defense peptide mimetic, brilacidin, potentiates caspofungin antifungal activity against human pathogenic fungi

dos Reis, T. F.; de Castro, P. A.; Bastos, R.; Pinzan, C. F.; Souza, P. F.; Ackloo, S.; Hossain, M. A.; Drewry, D.; Alkhazraji, S.; Ibrahim, A.; Jo, H.; deGrado, W. F.; Goldman, G.

10.1101/2022.09.28.509882 — microbiology — Posted on 2022-09-28

344 Achieving quantitative and accurate measurement of the human gut microbiome

Maghini, D. G.; Dvorak, M.; Dahlen, A.; Roos, M.; Kuersten, S.; Bhatt, A. S.

10.1101/2022.09.28.509972 — microbiology — Posted on 2022-09-28

345 Treatment of Hydrocephalus by Decreasing Inflammatory Cytokine Response Using GIT 27

Zaranek, M. G.; Harris, C.

10.1101/2022.09.28.509923 — neuroscience — Posted on 2022-09-28

346 Red Palm Oil (RPO) May Enhance Chronic Inflammation Through Disturbance in Lipid Metabolism

Binyameen, R. B.; Akinola, F.

10.1101/2022.09.28.509863 — physiology — Posted on 2022-09-28

347 A Purinergic Mechanism Underlying Metformin Regulation of Hyperglycemia

Senfeld, J.; Peng, Q.; Shi, Y.; Qian, S.; Shen, J.

10.1101/2022.09.27.509754 — pharmacology and toxicology — Posted on 2022-09-28

348 Systematic analysis of in-source modifications of primary metabolites during flow-injection time-of-flight mass spectrometry

Farke, N.; Schramm, T.; Verhuelsdonk, A.; Link, H.

10.1101/2022.09.28.509873 — biochemistry — Posted on 2022-09-28

349 Novelty detection and multiple timescale integration drive Drosophila orientation dynamics in temporally diverse olfactory environments

Sehdev, A.; Jayaram, V.; Kadakia, N.; Brown, E.; Emonet, T.

10.1101/2022.09.28.509840 — animal behavior and cognition — Posted on 2022-09-28

350 Cardiac muscle-restricted partial loss of Nos1ap expression has limited impact on electro- and echo-cardiographic features

Smith, A.; Auer, D.; Johnson, M.; Sanchez, E.; Ross, H.; Ward, C.; Chakravarti, A.; Kapoor, A.

10.1101/2022.09.27.509782 — genetics — Posted on 2022-09-28

351 Not getting in too deep: a practical deep learning approach to routine crystallisation image classification

Wilson, J.; Milne, J.; Qian, C.; Hargreaves, D.; Wang, Y.

10.1101/2022.09.28.509868 — molecular biology — Posted on 2022-09-28

352 ePlatypus: an ecosystem for computational analysis of immunogenomics data

Kreiner, V.; Agrafiotis, A.; Cotet, T.-S.; Kuhn, R.; Shlesinger, D.; Manero-Carranza, M.; Khodaverdi, K.; Masserey, S.; Guerci, L.; Hong, K.-L.; Han, J.; Stiklioraitis, K.; Martinolli, V.; Dizerens, R.; Kilchenmann, S.; Stalder, L.; Nissen, L.; Vogelsanger, B.; Anzböck, S.; Laslo, D.; Kondorosy, M.; Venerito, M.; Garcia, A. S.; Feller, I.; Oxenius, A.; Reddy, S. T.; Yermanos, A.

10.1101/2022.09.28.509709 — immunology — Posted on 2022-09-28

353 eIF4E phosphorylation recruits β-catenin to mRNA cap and selectively promotes Wnt pathway translation in dentate gyrus LTP maintenance in vivo

Patil, S.; Chalkiadaki, K.; Mergiya, T.-F.; Simbriger, K.; Amorim, I. S.; Akerkar, S.; Gkogkas, C. G.; Bramham, C. R.

10.1101/2022.09.28.509312 — neuroscience — Posted on 2022-09-28

354 Cell type-independent profiling of interactions between intracellular pathogens and the human phosphoproteome

Mohler, K.; Moen, J.; Rogulina, S.; Rinehart, J.

10.1101/2022.09.27.509702 — synthetic biology — Posted on 2022-09-28

355 A mathematical model of potassium homeostasis: Effect of feedforward and feedback controls

Stadt, M.; Leete, J.; Devinyak, S.; Layton, A. T.

10.1101/2022.09.28.509841 — physiology — Posted on 2022-09-28

356 Control of lipolysis by a population of oxytocinergic sympathetic neurons

Li, E.; Wang, L.; Wang, D.; Chi, J.; Smith, G.; Klein, S.; Cohen, P.; Rosen, E.

10.1101/2022.09.27.509745 — physiology — Posted on 2022-09-28

357 The transcriptional landscape of glycosylation-related genes in cancer

Rodriguez, E.; Lindijer, D.; van Vliet, S. J.; Garcia-Vallejo, J. J.; van Kooyk, Y.

10.1101/2022.09.28.509853 — cancer biology — Posted on 2022-09-28

358 Predicting cell stress and strain during extrusion bioprinting

Mueller, S. J.; Fabry, B.; Gekle, S.

10.1101/2022.09.28.509836 — biophysics — Posted on 2022-09-28

359 m6A-ELISA, a simple method for quantifying N6-methyladenosine from mRNA populations

Ensinck, I.; Sideri, T.; Modic, M.; Capitanchik, C.; Toolan-Kerr, P.; van Werven, F.

10.1101/2022.09.27.509679 — biochemistry — Posted on 2022-09-28

360 Genome-wide regulatory effects of STRs stabilized by elevated expression of antioxidant genes in C. elegans

Zhang, G.; Andersen, E.

10.1101/2022.09.27.509703 — genetics — Posted on 2022-09-28

361 Tinamou egg color displacement at eco-geographical and song space overlap

Li, Q.; Chen, D.; Wang, S.

10.1101/2022.09.27.509793 — evolutionary biology — Posted on 2022-09-28

362 Hybridisation has shaped a recent radiation of grass-feeding aphids

Mathers, T. C.; Wouters, R. H. M.; Mugford, S. T.; Biello, R.; Van Oosterhout, C.; Hogenhout, S. A.

10.1101/2022.09.27.509720 — evolutionary biology — Posted on 2022-09-28

363 Decoupled spectral tuning and eye size diversification patterns in an Antarctic adaptive radiation

Yoder, E. B.; Parker, C. E.; Tew, A.; Jones, C. D.; Dornburg, A.

10.1101/2022.09.28.509872 — evolutionary biology — Posted on 2022-09-28

364 Seascape genomics reveals limited dispersal and suggest spatially varying selection among European populations of sea lamprey (Petromyzon marinus)

Baltazar-Soares, M.; Britton, J. R.; Pinder, A.; Harrison, A. J.; Nunn, A. D.; Quintella, B. R.; Mateus, C. S.; Bolland, J. D.; Dodd, J. R.; Almeida, P. R.; Almela, V. D.; Andreou, D.

10.1101/2022.09.28.509639 — evolutionary biology — Posted on 2022-09-28

365 Multi-scale observations of mangrove blue carbon fluxes; the NASA Carbon Monitoring System BlueFlux field campaign

Poulter, B.; Adams, F.; Amaral, C.; Barenblitt, A.; Campbell, A.; Charles, S.; Cuesta, R.; Delaria, E.; Doughty, C.; Fatoyinbo, T.; Gewirtzman, J.; Hanisco, T.; Hull, M.; Kawa, R.; Hannun, R.; Lagomasino, D.; Lait, L.; Malone, S.; Newman, P.; Raymond, P.; Rosentreter, J.; Thomas, N.; Wolfe, G.; Xiong, L.; Ying, Q.; Zhang, Z.

10.1101/2022.09.27.509753 — ecology — Posted on 2022-09-28

366 A genome-wide CRISPR screen implicates plasma membrane asymmetry in exogenous C6-ceramide toxicity

Morris, S. N. S.; Deol, K. K.; Lange, M.; Olzmann, J. A.

10.1101/2022.09.26.509629 — cell biology — Posted on 2022-09-28

367 Simple Neurofeedback via Machine Learning: Challenges in real time multivariate assessment of meditation state

Kuriakose, S. S.; Swamy, A.; Venugopal, R.; Sasidharan, A.

10.1101/2022.09.27.509655 — neuroscience — Posted on 2022-09-28

368 Nature of epigenetic aging from a single-cell perspective

Tarkhov, A. E.; Lindstrom-Vautrin, T.; Zhang, S.; Ying, K.; Moqri, M.; Zhang, B.; Gladyshev, V. N.

10.1101/2022.09.26.509592 — systems biology — Posted on 2022-09-28

369 Spatial control of ARGONAUTE-mediated RNA silencing in anther development

Tamotsu, H.; Koizumi, K.; Briones, A. V.; Komiya, R.

10.1101/2022.09.27.509800 — plant biology — Posted on 2022-09-28

370 Effects of more natural housing conditions on the muscular and skeletal characteristics of female C57BL/6J mice

Mieske, P.; Scheinpflug, J.; Yorgan, T.; Brylka, L.; Palme, R.; Hobbiesiefken, U.; Preikschat, J.; Diederich, K.; Lewejohann, L.

10.1101/2022.09.27.509671 — physiology — Posted on 2022-09-28

371 Lead (Pb) impairs thyroid hormone mediated changes in brain development and body length in Xenopus laevis tadpoles

Dahora, L. I.; Robinson, A. M.; Buenaventura, C.; Bailey, H.; Thompson, C. K.

10.1101/2022.09.27.509775 — pharmacology and toxicology — Posted on 2022-09-28

372 CDK4/6 inhibition and dsRNA sensor agonism co-operate to enhance anti-cancer effects through ER stress and immune modulation of tumour cells

Roulstone, V.; Kyula, J.; Wright, J.; Yu, L.; Barreiro Alonso, A.; Melake, M.; Choudhary, J.; Elliott, R.; Lord, C. J.; Mansfield, D.; Matthews, N.; Chauhan, R.; Jennings, V.; Chan, C.; Baldock, H.; Butera, F. J.; Appleton, E.; Nenclares, P.; Pedersen, M.; Foo, S.; Patin, E. C.; Rullan, A.; Tenev, T.; Meier, P.; van Vloten, J.; Vile, R.; Pandha, H.; Melcher, A.; McLaughlin, M.; Harrington, K. J.

10.1101/2022.09.28.508679 — cancer biology — Posted on 2022-09-28

373 Bridging-mediated compaction of mitotic chromosomes

Forte, G.; Boteva, L.; Gilbert, N.; Cook, P. R.; Marenduzzo, D.

10.1101/2022.09.27.509716 — biophysics — Posted on 2022-09-28

374 Moving beyond MARCO

Newman, J. M.; Rosa, N.; Watkins, C. J.

10.1101/2022.09.28.509867 — biophysics — Posted on 2022-09-28

375 A full computational model of cell motility: Early spreading, cell migration and competing taxis

Betorz, J.; Bokil, G. R.; Deshpande, S. M.; Kulkarni, S.; Rolando, D.; Venturini, C.; Saez, P.

10.1101/2022.09.28.509519 — biophysics — Posted on 2022-09-28

376 Comparative Study of State-Dependent Cholesterol Binding Sites in Adenosine A2A and A1 Receptors Using Coarse-Grained Molecular Dynamics Simulations in Biologically Relevant Membranes

Tzortzini, E.; Corey, R. A.; Kolocouris, A.

10.1101/2022.09.28.509875 — biophysics — Posted on 2022-09-28

377 Quartet DNA reference materials and datasets for comprehensively evaluating germline variants calling performance

Ren, L.; Duan, X.; Dong, L.; Zhang, R.; Yang, J.; Gao, Y.; Peng, R.; Hou, W.; Liu, Y.; Li, J.; Yu, Y.; Zhang, N.; Shang, J.; Liang, F.; Wang, D.; Chen, H.; Sun, L.; Hao, L.; Scherer, A.; Nordlund, J.; Xiao, W.; Xu, J.; Tong, W.; Hu, X.; Jia, P.; Ye, K.; Li, J.; Jin, L.; Shi, L.; Hong, H.; Wang, J.; Fan, S.; Fang, X.; Zheng, Y.

10.1101/2022.09.28.509844 — bioinformatics — Posted on 2022-09-28

378 Transcriptome analysis reveals hepatotoxicity in zebrafish induced by cyhalofop-butyl

Zhou, T.; Yang, Y.; Liu, T.

10.1101/2022.04.30.490149 — bioinformatics — Posted on 2022-09-28

379 Paracrine CSF1 signaling regulates macrophage migration dynamics towards ovarian cancer cells in a 3D microfluidic model that recapitulates in vivo infiltration patterns in patient-derived xenograft models

Scott, A.; Kulawiec, D.; Jazwinska, D.; Zervantonakis, I.

10.1101/2022.09.27.509704 — bioengineering — Posted on 2022-09-28

380 Ester-linked ubiquitin sites formed by HOIL-1 in TLR7 signaling include four novel ubiquitin dimers

McCrory, E. H.; Akimov, V.; Cohen, P.; Blagoev, B.

10.1101/2022.09.28.509890 — biochemistry — Posted on 2022-09-28

381 Highly Sensitive and Specific Amyloid-β Oligomers Detection Using CRISPR-Cas12a Probe System aided by Graphene Oxide for Early Diagnosis of Alzheimer's Diseases

Tang, J.; Zhu, Z.; Yang, C.

10.1101/2022.09.27.509482 — biochemistry — Posted on 2022-09-28

382 Permeability transition pore-related changes in the proteome and channel activity of ATP synthase dimers and monomers

Nikiforova, A.; Baburina, Y.; Borisova, M.; Surin, A.; Kharechkina, E.; Krestinina, O.; Suvorina, M.; Kruglova, S.; Kruglov, A.

10.1101/2022.09.28.508998 — biochemistry — Posted on 2022-09-28

383 Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients

Garcia-Mulero, S.; Fornelino, R.; Punta, M.; Lise, S.; Varela, M.; Moreno, R.; Costa-Garcia, M.; Gros, A.; Alemany, R.; Piulats, J. M.; Sanz-Pamplona, R.

10.1101/2022.09.28.509834 — genomics — Posted on 2022-09-28

384 Sharing GWAS summary statistics results in more citations: evidence from the GWAS catalog

Reales, G.; Wallace, C.

10.1101/2022.09.27.509657 — genomics — Posted on 2022-09-28

385 Genetic Regulators of Sputum Mucin Concentration and Their Associations with COPD Phenotypes

10.1101/2022.09.28.509838 — genetics — Posted on 2022-09-28

386 Enrichment of phenotype among biological forms of Anopheles stephensi Liston through establishment of isofemale lines

Ghosh, C.; Kumar, N.; Kushwah, R. B. S.; M, S.; Joshi, S. G.; R, C. K.; Alalamath, T.; Srinivasan, S.; Subramani, S.; Kumar, S.; Swain, S.

10.1101/2022.09.28.509862 — genetics — Posted on 2022-09-28

387 Global diversification of the common moonwort ferns (Botrychium lunaria group, Ophioglossaceae) was mainly driven by Pleistocene climatic shifts

Mossion, V.; Koenen, E.; Grant, J.; Croll, D.; Farrar, D. R.; Kessler, M.

10.1101/2022.09.28.509846 — evolutionary biology — Posted on 2022-09-28

388 Shifts in mutation bias promote mutators by altering the distribution of fitness effects

Tuffaha, M.; Varakunan, S.; Castellano, D.; Gutenkunst, R. N.; Wahl, L. M.

10.1101/2022.09.27.509708 — evolutionary biology — Posted on 2022-09-28

389 The phylogenetic placement of an enigmatic moth Egybolis vaillantina based on museomics

Zahiri, R.; Holloway, J. D.; Ghanavi, H. R.; Aarvik, L.; Wahlberg, N.

10.1101/2022.09.27.509790 — evolutionary biology — Posted on 2022-09-28

390 Simulated green turtle grazing reduces seagrass productivity and alters benthic community structure while triggering further disturbance by feeding stingrays

Cannon, A.; Hynes, M. G.; Brandt, M.; Wold, C.; O'Dea, A.; Altieri, A.; Smith, J. E.

10.1101/2022.09.27.509764 — ecology — Posted on 2022-09-28

391 Non-destructive collection and metabarcoding of arthropod environmental DNA remained on a terrestrial plant

Yoneya, K.; Ushio, M.; Miki, T.

10.1101/2022.09.27.509650 — ecology — Posted on 2022-09-28

392 Acclimating to degraded environments: The social rationale for swift action on restoration

Karatayev, V. A.; Wilson, R. S.; Webster, D. G.; Axelrod, M.; Bauch, C. T.; Anand, M.

10.1101/2022.09.27.509807 — ecology — Posted on 2022-09-28

393 Long-ranged formation of the Bicoid gradient requires multiple dynamic modes that spatially vary across the embryo

Athilingam, T.; Nelanuthala, A. V. S.; Breen, C.; Wohland, T.; Saunders, T. E.

10.1101/2022.09.28.509874 — developmental biology — Posted on 2022-09-28

394 Loss of the E3 ubiquitin ligases UBR-5 or HECD-1 restores Caenorhabditis elegans development in the absence of SWI/SNF function

Lampersberger, L.; Conte, F.; Ghosh, S.; Xiao, Y.; Price, J.; Jordan, D.; Matus, D. Q.; Sarkies, P.; Beli, P.; Miska, E. A.; Burton, N. O.

10.1101/2022.09.27.509717 — developmental biology — Posted on 2022-09-28

395 A filamentous phage triggers antiviral responses in cystic fibrosis basal airway epithelial cells

Popescu, M. C.; Haddock, N. L.; Burgener, E. B.; Rojas-Hernandez, L. S.; Kaber, G.; Hargil, A.; Bollyky, P.; Milla, C. E.

10.1101/2022.09.27.509771 — cell biology — Posted on 2022-09-28

396 Enhanced Complex Stability and Optimal JAK Geometry are Pivotal for a Potent Type III Interferon Response

Aung, T.; Horvath, C. M.; Mendoza, J. L.

10.1101/2022.09.27.508945 — cell biology — Posted on 2022-09-28

397 Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts

Blokland, K. E. C.; Nizamoglu, M.; Habibie, H.; Borghuis, T.; Schuliga, M.; Melgert, B. N.; Knight, D. A.; Brandsma, C.-A.; Pouwels, S. D.; Burgess, J. K.

10.1101/2022.09.27.509806 — cell biology — Posted on 2022-09-28

398 Structural and Immunological Similarities Between the Metacyclic and Bloodstream Form Variant Surface Glycoproteins of the African Trypanosome

Chandra, M.; Dakovic, S.; Foti, K.; Zeelen, J.; van Straaten, M.; Aresta-Branco, F.; Tihon, E.; Luebbehusen, N.; Ruppert, T.; Glover, L.; Papavasiliou, F. N.; Stebbins, C. E.

10.1101/2022.09.28.508705 — microbiology — Posted on 2022-09-28

399 Diet-induced obesity alters intestinal monocyte-derived and tissue-resident macrophages in female mice independent of TNF

Breznik, J. A.; Jury, J.; Verdu, E. F.; Sloboda, D. M.; Bowdish, D. M.

10.1101/2022.09.27.509732 — immunology — Posted on 2022-09-28

400 Commensal-specific CD4 T cells promote inflammation in the central nervous system via molecular mimicry

White, Z.; Cabrera, I.; Ochoa-Raya, A.; Kapustka, I.; Koster, K. P.; Matsuo, T.; Jayawardena, D.; Kageyama, T.; Dudeja, P. K.; Lutz, S. E.; Yoshii, A.; Sano, T.

10.1101/2022.09.27.509786 — immunology — Posted on 2022-09-28

401 Cellular proteomic profiling using proximity labelling by TurboID-NES in microglial and neuronal cell lines.

Sunna, S.; Bowen, C.; Zeng, H.; Rayaprolu, S.; Kumar, P.; Bagchi, P.; Guo, Q.; Duong, D. M.; Bitarafan, S.; Natu, A.; Wood, L.; Seyfried, N. T.; Rangaraju, S.

10.1101/2022.09.27.509765 — neuroscience — Posted on 2022-09-28

402 Characterising modulatory effects of transcranial random noise stimulation using the perceptual template model.

Gotsis, S.; van Boxtel, J. J. A.; Teufel, C.; Edwards, M.; Christensen, B. K.

10.1101/2022.09.27.509805 — neuroscience — Posted on 2022-09-28

403 Characterising stationary and dynamic effective connectivity changes in the motor network during and after tDCS

Calzolari, S.; Jalali, R.; Fernandez-Espejo, D.

10.1101/2022.09.27.509681 — neuroscience — Posted on 2022-09-28

404 Disruption of Tonic Endocannabinoid Signaling Triggers the Generation of a Stress Response

Petrie, G.; Balsevich, G.; Fuzesi, T.; Aukema, R.; Wouter, D.; Van der Stelt, M.; Bains, J. S.; Hill, M. N.

10.1101/2022.09.27.509585 — neuroscience — Posted on 2022-09-28

405 Travelling waves observed in MEG data can be explained by two discrete sources

Zhigalov, A.; Jensen, O.

10.1101/2022.09.28.509870 — neuroscience — Posted on 2022-09-28

406 Cones and Cone Pathways Remain Functional in Advanced Retinal Degeneration

Ellis, E. M.; Paniagua, A. E.; Scalabrino, M. L.; Thapa, M.; Rathinavelu, J.; Jiao, Y.; Williams, D. S.; Field, G. D.; Fain, G. L.; Sampath, A. P.

10.1101/2022.09.27.509752 — neuroscience — Posted on 2022-09-28

407 Chemotaxonomy of Tapinoma and some Dolichoderinae ants from Europe and North Africa

Lenoir, A.; Perdereau, E.; Berville, L.

10.1101/2022.09.28.509850 — zoology — Posted on 2022-09-28

408 Extremely low sample size allows age and growth estimation in a rare and threatened shark

Kyne, P. M.; Smart, J. J.; Johnson, G.

10.1101/2022.09.26.509619 — zoology — Posted on 2022-09-28

409 A scalable screening platform for phenotypic subtyping of ALS patient-derived fibroblasts

Kumbier, K.; Roth, M.; Li, Z.; Lazzari-Dean, J.; Waters, C.; Huang, P.; Korobeynikov, V.; Consortium, N. Y. G. C.; Phatnani, H.; Schneider, N.; Jacobson, M.; Wu, L.; Altschuler, S.

10.1101/2022.09.27.509770 — systems biology — Posted on 2022-09-28

410 A Genome Scale Transcriptional Regulatory Model of the Human Placenta

Paquette, A. G.; Ahuna, K.; Hwang, Y. M.; Pearl, J.; Liao, H.; Shannon, P.; Kadam, L.; Lapehn, S.; Bucher, M.; Roper, R.; Funk, C. C.; MacDonald, J.; Bammler, T.; Baloni, P.; Brockway, H.; Mason, W. A.; Bush, N.; LeWinn, K. Z.; Carr, C. J.; Stamatoyannopoulos, J.; Muglia, L. J.; Jones, H. M.; Sadovsky, Y.; Myatt, L.; Sathyanarayana, S.; Price, N.; Environmental influences on Child Health Outcomes,

10.1101/2022.09.27.509541 — systems biology — Posted on 2022-09-28

411 The Quartet Data Portal: integration of community-wide resources for multiomics quality control

Yang, J.; Liu, Y.; Shang, J.; Chen, Q.; Chen, Q.; Ren, L.; Zhang, N.; Yu, Y.; Li, Z.; Song, Y.; Yang, S.; Scherer, A.; Tong, W.; Hong, H.; Shi, L.; Xiao, W.; Zheng, Y.

10.1101/2022.09.26.507202 — systems biology — Posted on 2022-09-28

412 Multi-scale spatial modeling of immune cell distributions enables survival prediction in primary central nervous system lymphoma

Roemer, M. G. M.; van de Brug, T.; Bosch, E.; Berry, D.; Hijmering, N.; Stathi, P.; Weijers, K.; Doorduijn, J.; Broemberg, J.; van de Wiel, M.; Ylstra, B.; de Jong, D.; Kim, Y.

10.1101/2022.09.27.509403 — systems biology — Posted on 2022-09-28

413 Identification of Rho-dependent termination site in vivo using synthetic sRNA

Wang, X.; N, M. P. A.; Jeon, H. J.; He, J.; Lim, H. M.

10.1101/2022.09.26.509630 — synthetic biology — Posted on 2022-09-28

414 Testing the evolutionary drivers of nitrogen-fixing symbioses in challenging soil environments

Siniscalchi, C. M.; Kates, H. R.; Soltis, P. R.; Soltis, D. E.; Guralnick, R. P.; Folk, R. A.

10.1101/2022.09.27.509719 — plant biology — Posted on 2022-09-28

415 Comprehensive Analysis of Peptide-Coding Genes Identifies an LRR-only Microprotein That Regulates Reproductive Organs in Marchantia polymorpha

Kobayashi, H.; Sugano, S. S.; Tamura, K.; Oka, Y.; Matsushita, T.; Shimada, T.

10.1101/2022.09.27.509623 — plant biology — Posted on 2022-09-28

416 The p-rpS6-zone delineates wounding response and the healing process

Ring, N. A. R.; Dworak, H.; Bachmann, B.; Schaedl, B.; Valdivieso, K.; Rozmaric, T.; Heimel, P.; Schuetzenberger, K.; Leinfellner, G.; Ferguson, J.; Drechsler, S.; Mildner, M.; Schosserer, M.; Slezak, P.; Meyuhas, O.; Gruber, F.; Grillari, J.; Redl, H.; Ogrodnik, M.

10.1101/2022.09.27.507541 — physiology — Posted on 2022-09-28

417 Mechanisms of Antimicrobial Agent Cetylpyridinium Chloride Mitochondrial Toxicity in Rodent and Primary Human Cells: Super-resolution Microscopy Reveals Nanostructural Disruption

Weller, S. R.; Burnell, J. E.; Aho, B. M.; Obeng, B.; Ledue, E. L.; Shim, J. K.; Hess, S. T.; Gosse, J. A.

10.1101/2022.09.27.509813 — pharmacology and toxicology — Posted on 2022-09-28

418 Impact of vancomycin loading doses and dose escalation on glomerular function and kidney injury biomarkers in a translational rat model

Chang, J.; Pais, G.; Engel, P. L.; Klimek, P.; Marianski, S.; Valdez, K.; Scheetz, M. H.

10.1101/2022.09.26.509628 — pharmacology and toxicology — Posted on 2022-09-28

419 Pharmacological hallmarks of allostery at the M4 muscarinic receptor elucidated through structure and dynamics

Vuckovic, Z.; Wang, J.; Pham, V.; Mobbs, J. I.; Belousoff, M. J.; Bhattarai, A.; Burger, W. A. C.; Thompson, G.; Yeasmin, M.; Leach, K.; van der Westhuizen, E. T.; Khajehali, E.; Liang, Y.-L.; Glukhova, A.; Wootten, D.; Lindsley, C. W.; Tobin, A.; Sexton, P.; Danev, R.; Valant, C.; Miao, Y.; Christopoulos, A.; Thal, D. M.

10.1101/2022.09.27.509640 — pharmacology and toxicology — Posted on 2022-09-28

420 Integrative Single Cell Multiomic Profiling Analysis Reveals HOX-PBX Gene Regulatory Network Contributing to the Survival of mTOR Hyperactive Cells

Olatoke, T. F.; Wagner, A.; Astrinidis, A. A.; Guo, M.; Zhang, E. Y.; Zhang, A. A.; Mattam, U.; Chilton, K.; Kopras, E. J.; Gupta, N.; Smith, E. P.; Karbowniczek, M.; Markiewski, M. M.; Wikenheiser-Brokamp, K.; Whitsett, J. A.; McCormack, F. X.; Xu, Y.; Yu, J. J.

10.1101/2022.09.27.509560 — cancer biology — Posted on 2022-09-28

421 Small-molecule Polθ inhibitors provide safe and effective tumor radiosensitization in preclinical models

Rodriguez-Berriguete, G.; Ranzani, M.; Prevo, R.; Puliyadi, R.; Machado, N.; Bolland, H. R.; Millar, V.; Ebner, D.; Boursier, M.; Cerutti, A.; Cicconi, A.; Galbiati, A.; Grande, D.; Grinkevich, V.; Majithiya, J.; Piscitello, D.; Rajendra, E.; Stockley, M.; Boulton, S. J.; Hammond, E. M.; Heald, R.; Smith, G. C. M.; Robinson, H.; Higgins, G. S.

10.1101/2022.09.27.509658 — cancer biology — Posted on 2022-09-28

422 miR-28 plus ibrutinib as a novel combination therapy for Diffuse Large B Cell Lymphoma

Fuertes, T.; Alvarez-Corrales, E.; Ubieto-Capella, P.; Serrano-Navarro, A.; Gomez-Escolar, C.; de Molina, A.; Mendez, J.; Ramiro, A. R.; de Yebenes, V. G.

10.1101/2022.09.27.509662 — cancer biology — Posted on 2022-09-28

423 CD26-negative and CD26-positive tissue-resident fibroblasts contribute to functionally distinct CAF subpopulations in breast cancer

Houthuijzen, J. M.; de Bruijn, R.; van der Burg, E.; Drenth, A. P.; Wientjens, E.; Filipovic, T.; Bullock, E.; Brambillasca, C. S.; Nieuwland, M.; de Rink, I.; van Diepen, F.; Klarenbeek, S.; Kerkhoven, R.; Brunton, V.; Scheele, C. L. G. J.; Boelens, M. C.; Jonkers, J.

10.1101/2022.09.27.509697 — cancer biology — Posted on 2022-09-28

424 PINK1 supports colorectal cancer growth by regulating the labile iron pool.

Chen, B.; Das, N. K.; Talukdar, I.; Singhal, R.; Castillo, C.; Andren, A.; Mancias, J. D.; Lyssiotis, C. A.; Shah, Y. M.

10.1101/2022.09.27.509713 — cancer biology — Posted on 2022-09-28

425 L1 retrotransposition is regulated post-transcriptionally In High-Grade Serous Ovarian Cancer

Pradhan, B.; Zhang, K.; Li, Y.; Lavikka, K.; Muranen, T.; Huhtinen, K.; Badge, R. M.; Burns, K.; Hynninen, J.; Hietanen, S.; Oikkonen, J.; Hautaniemi, S.; Kauppi, L.

10.1101/2022.09.27.509826 — cancer biology — Posted on 2022-09-28

426 Classification of Dielectric Microparticles by Microwave Impedance Cytometry

Sari, B.; Tefek, U.; Hanay, M. S.

10.1101/2022.09.27.509785 — biophysics — Posted on 2022-09-28

427 Caveolae govern plasma membrane mechanics to protect cells against EDIN B-induced transcellular tunnel formation and lethality from S. aureus septicaemia

Morel, C.; Lemerle, E.; Tsai, F.-C.; Obadia, T.; Srivastava, N.; Marechal, M.; Salles, A.; Albert, M.; Stefani, C.; Lamaze, C.; Vassilopoulos, S.; Piel, M.; Bassereau, P.; Gonzalez-Rodriguez, D.; Leduc, C.; Lemichez, E.

10.1101/2022.09.27.509635 — biophysics — Posted on 2022-09-28

428 Distinct Activation Mechanisms Regulate Subtype Selectivity of Cannabinoid Receptors

Dutta, S.; Shukla, D.

10.1101/2022.09.27.509760 — biophysics — Posted on 2022-09-28

429 Nanoscale infrared spectroscopy identifies parallel to antiparallel beta sheet transformation of Aβ fibrils

Banerjee, S.; Baghel, D.; Hasan ul Iqbal, M.; Ghosh, A.

10.1101/2022.09.27.509729 — biophysics — Posted on 2022-09-28

430 Analysis of noisy transient signals based on Gaussian process regression

Baglaeva, I.; Iaparov, B.; Zahradnik, I.; Zahradnikova, A.

10.1101/2022.09.27.509665 — biophysics — Posted on 2022-09-28

431 Virtual histology of Alzheimer's Disease: why are amyloid-β plaques visible with X-ray phase-contrast imaging?

Chourrout, M.; Sandt, C.; Weitkamp, T.; Ducic, T.; Meyronet, D.; Baron, T.; Klohs, J.; Rama, N.; Boutin, H.; Singh, S.; Olivier, C.; Wiart, M.; Brun, E.; Bohic, S.; Chauveau, F.

10.1101/2022.09.27.509706 — biophysics — Posted on 2022-09-28

432 Exploring protein sequence similarity with Protein Language UMAPs (PLUMAPs)

Jinich, A.; Nazia, S. Z.; Rhee, K. Y.

10.1101/2022.09.27.509824 — bioinformatics — Posted on 2022-09-28

433 DREAMS: Deep Read-level Error Model for Sequencing data applied to low-frequency variant calling and circulating tumor DNA detection

Christensen, M. H.; Drue, S.; Rasmussen, M. H.; Frydendahl, A.; Lyskjaer, I.; Demuth, C.; Nors, J.; Gotschalck, K. A.; Iversen, L. H.; Andersen, C. L.; Pedersen, J. S.

10.1101/2022.09.27.509150 — bioinformatics — Posted on 2022-09-28

434 Benchmarking strategies for cross-species integration of single-cell RNA sequencing data

Song, Y.; Miao, Z.; Brazma, A.; Papatheodorou, I.

10.1101/2022.09.27.509674 — bioinformatics — Posted on 2022-09-28

435 Analysis of the abomasal transcriptome of LDA affected cattle

Gal, Z.; Biro, B.; Nagy, Z.; Kontra, L.; Horvath, A.; Hoffmann, O. I.

10.1101/2022.09.27.509652 — bioinformatics — Posted on 2022-09-28

436 Real-Time Spatial Registration for 3D Human Atlas

Chen, L.; Teng, D.; Zhu, T.; Kong, J.; Herr, B.; Bueckle, A.; Borner, K.; Wang, F.

10.1101/2022.09.27.509335 — bioinformatics — Posted on 2022-09-28

437 Light-induced nanoscale deformation in azobenzene thin film triggers rapid intracellular Ca2+ increase via mechanosensitive cation channels

Peussa, H. M.; Fedele, C.; Tran, H.; Fadjukov, J.; Mäntylä, E.; Priimägi, A.; Nymark, S.; Ihalainen, T. O.

10.1101/2022.09.27.509666 — bioengineering — Posted on 2022-09-28

438 Genome-scale mapping of functional genes and loci in bacteria for industrial phenotypes

Yuan, Y.; Liao, X.; Shuang, L.; Xing, X.-h.; Zhang, C.

10.1101/2022.09.27.509808 — bioengineering — Posted on 2022-09-28

439 Machine learning and hypothesis driven optimization of bull semen cryopreservation media

Tu, F.; Bhat, M.; Blondin, P.; Vincent, P.; Sharafi, M.; Benson, J. D.

10.1101/2022.09.27.509504 — bioengineering — Posted on 2022-09-28

440 Targeting the Hedgehog Signaling Pathway to Improve Tendon-to-Bone Integration

Kamalitdinov, T. B.; Fujino, K.; Lang, S. K.; Jiang, X.; Madi, R.; Evans, M. K.; Zgonis, M. H.; Kuntz, A. F.; Dyment, N. A.

10.1101/2022.09.27.509810 — bioengineering — Posted on 2022-09-28

441 Effect of Nonlinear Hyperelastic Property of Arterial Tissues on the Pulse Wave Velocity based on the Unified-Fiber-Distribution (UFD) Model

Dong, H.; Liu, M.; Woodall, J.; Leshnower, B.; Gleason, R. L.

10.1101/2022.09.27.509711 — bioengineering — Posted on 2022-09-28

442 Yeast mtDNA transcription initiation in single nucleotide addition steps

Goovaerts, Q.; Shen, J.; De Wijngaert, B.; Basu, U.; Patel, S. S.; Das, K.

10.1101/2022.09.27.509796 — biochemistry — Posted on 2022-09-28

443 Metabolic Stability of the Demyelination PET tracer 3F4AP and Identification of its Metabolites

Sun, Y.; Ramos-Torres, K.; Brugarolas, P.

10.1101/2022.09.27.509607 — biochemistry — Posted on 2022-09-28

444 Inter-gastruloid heterogeneity revealed by single cell transcriptomics time course: implications for organoid based perturbation studies

Rosen, L. U.; Stapel, L. C.; Argelaguet, R.; Barker, C. G.; Yang, A.; Reik, W.; Marioni, J. C.

10.1101/2022.09.27.509783 — genomics — Posted on 2022-09-28

445 Single cell transcriptomics delineates the immune-cell landscape in equine lower airways and reveals upregulation of the FKBP5 gene in horses with asthma

Riihimaki, M.; Fegraeus, K.; Nordlund, J.; Waern, I.; Wernersson, S.; Akula, S.; Hellman, L.; Raine, A.

10.1101/2022.09.27.509660 — genomics — Posted on 2022-09-28

446 DNA methylation of the endothelin receptor B makes blue fish yellow

Fang, W.; Blakkan, D.; Bashier, R.; Lee, G. G.; Fernald, R. D.; Alvarado, S. G.

10.1101/2022.09.27.509821 — genetics — Posted on 2022-09-28

447 Correction for participation bias in the UK Biobank reveals non-negligible impact on genetic associations and downstream analyses

Schoeler, T.; Speed, D.; Porcu, E.; Pirastu, N.; Pingault, J.-B.; Kutalik, Z.

10.1101/2022.09.28.509845 — genetics — Posted on 2022-09-28

448 Genetic diversity, paternal origin and pathogen resistance in Cataglyphis desert ants

Eyer, P. A.; Guery, P. A.; Aron, S.

10.1101/2022.09.27.509653 — evolutionary biology — Posted on 2022-09-28

449 Adaptive structural and functional evolution of the placenta protects fetal growth in high elevation deer mice

Wilsterman, K.; Moore, E. C.; Schweizer, R. M.; Cunningham, K.; Good, J. M.; Cheviron, Z. A.

10.1101/2022.09.27.509814 — evolutionary biology — Posted on 2022-09-28

450 Interactions between insect vectors and plant pathogens span the parasitism-mutualism continuum

Santiago, M. F. M.; King, K. C.; Drew, G. C.

10.1101/2022.09.27.509661 — evolutionary biology — Posted on 2022-09-28

451 Cytoophidia safeguard binucleation of Drosophila male accessory gland cells

You, D.-D.; Zhou, X.; Wang, Q.-Q.; Liu, J.-L.

10.1101/2022.09.27.509809 — developmental biology — Posted on 2022-09-28

452 Regulating the timing of enhancer transitions is key to defining sharp boundaries of Fushi tarazu expression in the Drosophila embryo

Birnie, A.; Plat, A.; Bothma, J. P.

10.1101/2022.09.27.509025 — developmental biology — Posted on 2022-09-28

453 A Single-Cell Level Comparison of Human Inner Ear Organoids and the Human Cochlea and Vestibular Organs

van der Valk, W. H.; van Beelen, E. S. A.; Steinhart, M. R.; Nist-Lund, C.; de Groot, J. C. M. J.; van Benthem, P. P. G.; Koehler, K. R.; Locher, H.

10.1101/2022.09.28.509835 — developmental biology — Posted on 2022-09-28

454 The TBX20-TLE Interaction is Essential for the Second Heart Field

Edwards, W.; Bussey, O.; Conlon, F.

10.1101/2022.09.27.509637 — developmental biology — Posted on 2022-09-28

455 The Rho GTPase exchange factor Vav2 promotes extensive age-dependent rewiring of the skin stem cell transcriptome

Lorenzo-Martin, L. F.; Bustelo, X. R.

10.1101/2022.09.27.509634 — cell biology — Posted on 2022-09-28

456 YAP/TAZ inactivation with simvastatin attenuates glucocorticoid-induced human trabecular meshwork cell dysfunction

Yoo, H.; Singh, A.; Li, H.; Strat, A. N.; Bague, T.; Ganapathy, P. S.; Herberg, S.

10.1101/2022.09.27.509788 — cell biology — Posted on 2022-09-28

457 Endosomal Chemokine Receptor Signalosomes Regulate Central Mechanisms Underlying Cell Migration

Hahn, H.; Daly, C.; Little, J.; Perry-Hauser, N. A.; Inoue, A.; Plouffe, B.; Thomsen, A. R. B.

10.1101/2022.09.27.509755 — cell biology — Posted on 2022-09-28

458 Accurate and efficient constrained molecular dynamics of polymers through Newton's method and special purpose code

Lopez-Villellas, L.; Kjelgaard Mikkelsen, C. C.; Galano-Frutos, J. J.; Marco-Sola, S.; Alastruey-Benede, J.; Ibanez, P.; Moreto, M.; Sancho, J.; Garcia-Risueno, P.

10.1101/2022.09.28.509839 — molecular biology — Posted on 2022-09-28

459 Drug interaction mapping with proximity dependent enzyme recruiting chimeras

Venable, J. D.; Vashisht, A. A.; Rayatpisheh, S.; Lajiness, J. P.; Phillips, D. P.; Brock, A.

10.1101/2022.09.26.509259 — molecular biology — Posted on 2022-09-28

460 Initial and ongoing tobacco smoking elicits vascular damage and distinct inflammatory response linked to neurodegeneration

Garza, A. P.; Morton, L.; Pallinger, E.; Buzas, E. I.; Schreiber, S.; Schott, B. H.; Dunay, I. R.

10.1101/2022.09.27.509833 — immunology — Posted on 2022-09-28

461 Major Contribution of Myeloid Cells In TB specific Host Gene Signature: Revelations from Re-Analysis of Publicly Available Datasets

Gautam, A.; Mohapatra, S. K.; Pandit, B.

10.1101/2022.09.27.508979 — immunology — Posted on 2022-09-28

462 Profound immunomodulatory effects of 225Ac-NM600 drive enhanced anti-tumor responsein prostate cancer

de Aguiar Ferreira, C.; Potluri, H. K.; Massey, C.; Grudzinski, J. J.; Carston, A.; Clemons, N.; Thickens, A. S.; Rosenkrans, Z.; Choi, C.; Pinchuk, A.; Kwon, O.; Jeffery, J. J.; Bednarz, B.; Morris, Z.; Weichert, J.; McNeel, D. G.; Hernandez, R.

10.1101/2022.09.26.509374 — immunology — Posted on 2022-09-28

463 High-resolution analysis of individual Drosophila melanogaster larvae within groups uncovers inter- and intra-individual variability in locomotion and its neurogenetic modulation

Thane, M.; Paisios, E.; Stöter, T.; Krüger, A.-R.; Gläss, S.; Dahse, A.-K.; Scholz, N.; Gerber, B.; Lehmann, D. J.; Schleyer, M.

10.1101/2022.09.27.509663 — neuroscience — Posted on 2022-09-28

464 Large scale interrogation of retinal cell functions by 1-photon light-sheet microscopy

Roy, S.; Wang, D.; Rudzite, A. M.; Perry, B.; Scalabrino, M. L.; Thapa, M.; Gong, Y.; Sher, A.; Field, G. D.

10.1101/2022.09.26.508527 — neuroscience — Posted on 2022-09-28

465 Cerebral Small Vessel Disease Burden is Associated with Decreased Abundance of Gut Barnesiella intestinihominis Bacterium in the Framingham Heart Study

Fongang, B.; Satizabal, C. L.; Kautz, T. F.; Ngouongo, Y. W.; SherraeMuhammad, J. A.; Vasquez, E.; Mathews, J.; Goss, M.; Saklad, A. R.; Himali, J.; Beiser, A.; Cavazos, J. E.; Mahaney, M. C.; Maestre, G.; DeCarli, C.; Shipp, E. L.; Vasan, R. S.; Seshadri, S.

10.1101/2022.09.27.509283 — neuroscience — Posted on 2022-09-28

466 Common population codes produce extremely nonlinear neural manifolds

De, A.; Chaudhuri, R.

10.1101/2022.09.27.509823 — neuroscience — Posted on 2022-09-28

467 MHC class I and MHC class II reporter mice enable analysis of immune oligodendroglia in mouse models of multiple sclerosis

Harrington, E. P.; Catenacci, R. B.; Smith, M. D.; Heo, D.; Miller, C. E.; Meyers, K. R.; Glatzer, J.; Bergles, D. E.; Calabresi, P. A.

10.1101/2022.09.27.509669 — neuroscience — Posted on 2022-09-28

468 The Developmental Profile of Visual Cortex Astrocytes

Watanabe, A.; Guo, C.; Sjostrom, P. J.

10.1101/2022.09.27.509759 — neuroscience — Posted on 2022-09-28

469 Decoding Age-specific Changes in Brain Functional Connectivity Using a Sliding-window Based Clustering Method

Zhang, A.; Pagliaccio, D.; Marsh, R.; Lee, S.

10.1101/2022.09.27.509677 — neuroscience — Posted on 2022-09-28

470 Trends in self-citation rates in neuroscience literature

Rosenblatt, M.; Mehta, S.; Peterson, H.; Dadashkarimi, J.; Rodriguez, R. X.; Foster, M. L.; Adkinson, B. D.; Liang, Q.; Kimble, V. M.; Ye, J.; McCusker, M. C.; Farruggia, M. C.; Rolison, M.; Westwater, M. L.; Jiang, R.; Noble, S.; Scheinost, D.

10.1101/2022.09.27.509533 — neuroscience — Posted on 2022-09-28

471 Pericytes control vascular stability and auditory spiral ganglion neuron survival

Zhang, Y.; Neng, L.; Sharma, K.; Hou, Z.; Johnson, A.; Song, J.; Dabdoub, A.; Shi, X.

10.1101/2022.09.27.509698 — neuroscience — Posted on 2022-09-28

472 Classic and dissociative psychedelics induce similar hyper-synchronous states in the cognitive-limbic cortex-basal ganglia system

Brys, I.; Barrientos, S. A.; Ward, J. E.; Wallander, J.; Petersson, P.; Halje, P.

10.1101/2022.09.27.509527 — neuroscience — Posted on 2022-09-28

473 The Neurotoxin DSP-4 Dysregulates the Locus Coeruleus-Norepinephrine System and Recapitulates Molecular and Behavioral Aspects of Prodromal Neurodegenerative Disease

Iannitelli, A. F.; Kelberman, M. A.; Lustberg, D. J.; Korukonda, A.; McCann, K. E.; Mulvey, B.; Segal, A.; Liles, L. C.; Sloan, S. A.; Dougherty, J.; Weinshenker, D.

10.1101/2022.09.27.509797 — neuroscience — Posted on 2022-09-28

474 Specific connectivity optimizes learning in thalamocortical loops

Lakshminarasimhan, K.; Xie, M.; Cohen, J. D.; Sauerbrei, B.; Hantman, A. W.; Litwin-Kumar, A.; Escola, S.

10.1101/2022.09.27.509618 — neuroscience — Posted on 2022-09-28

475 α2-ADRENERGIC MODULATION OF Ih IN ADULT-BORN GRANULE CELLS IN THE OLFACTORY BULB

Hu, R.; Shankar, J.; Dong, G. Z.; Villar, P. S.; Araneda, R. C.

10.1101/2022.09.27.509763 — neuroscience — Posted on 2022-09-28

476 An analysis of laboratory variability and thresholds for human in vitro ADME/PK methods

Fagerholm, U.

10.1101/2022.09.27.509731 — pharmacology and toxicology — Posted on 2022-09-28

477 Spatial tumour gene signature discriminates neoplastic from non-neoplastic compartments in colon cancer: unravelling predictive biomarkers for relapse

Sallinger, K.; Gruber, M.; Mueller, C.-T.; Bonstingl, L.; Pritz, E.; Pankratz, K.; Gerger, A.; Smolle, M. A.; Aigelsreiter, A.; Surova, O.; Svedlund, J.; Nilsson, M.; Kroneis, T.; El-Heliebi, A.

10.1101/2022.09.27.509641 — cancer biology — Posted on 2022-09-28

478 Identification and characterization of four bacteriome- and mycobiome-derived subtypes in tumour and adjacent mucosa tissue of colorectal cancer patients

Salvucci, M.; Poynter, L.; Minerzami, R.; Carberry, S.; O'Byrne, R.; Alexander, J.; Lambrechts, D.; Veselkov, K.; Kinross, J.; Prehn, J. H. M.

10.1101/2022.09.27.509391 — cancer biology — Posted on 2022-09-28

479 Titrating CD47 by mismatch CRISPRi reveals incomplete repression can eliminate IgG-opsonized tumors but CD47 heterogeneity limits induction of anti-tumor IgG

Hayes, B. H.; Zhu, H.; Andrechak, J. C.; Discher, D. E.

10.1101/2022.09.27.509740 — cancer biology — Posted on 2022-09-28

480 Diversity, Equity, and Inclusion in the Melanoma Research Community

Portuallo, M. E.; Lu, D. Y.; Alicea, G. M.; Bolling, J.; Lee, R.; McQuade, J.; Warner, A. B.; Davies, M.; Weeraratna, A.; Villanueva, J.; Rebecca, V. W.

10.1101/2022.09.24.509278 — cancer biology — Posted on 2022-09-28

481 Serum amyloid alpha 1-2 are not required for systemic inflammation in the 4T1 murine breast cancer model

He, C.; Konishi, R.; Harata, A.; Nakamura, Y.; Mizuno, R.; Yoda, M.; Toi, M.; Kawaguchi, K.; Kawaoka, S.

10.1101/2022.09.26.509617 — cancer biology — Posted on 2022-09-28

482 Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

Kauko, O.; Turunen, M.; Pihlajamaa, P.; Hakkinen, A.; Queiroz, R. M.; Paakkonen, M.; Ventela, S.; Gaetani, M.; Lundstrom, S.; Murgia, A.; Sahu, B.; Routila, J.; Irjala, H.; Griffin, J. L.; Lilley, K. S.; Kivioja, T.; Hautaniemi, S.; Taipale, J.

10.1101/2022.09.27.509636 — cancer biology — Posted on 2022-09-28

483 Murine breast cancers disorganize the liver transcriptome in zonated manners

Vandenbon, A.; Mizuno, R.; Konishi, R.; Onishi, M.; Masuda, K.; Kobayashi, Y.; Kawamoto, H.; Suzuki, A.; Shimizu, M.; Tanaka, Y.; Suzuki, Y.; Kawaoka, S.

10.1101/2022.09.27.509354 — cancer biology — Posted on 2022-09-28

484 The human MRS2 magnesium binding domain is a regulatory feedback switch for channel activity.

Uthayabalan, S.; Vishnu, N.; Madesh, M.; Stathopulos, P.

10.1101/2022.09.27.509701 — biophysics — Posted on 2022-09-28

485 Size and position dependent cytoplasm viscoelasticity through hydrodynamic interactions with the cell surface

Najafi, J.; Dmitrieff, S.; Minc, N.

10.1101/2022.09.27.509722 — biophysics — Posted on 2022-09-28

486 Uncovering the Mechanism of the Proton-Coupled Fluoride Transport in the CLCF Antiporter

Mills, K.; Torabifard, H.

10.1101/2022.09.27.509787 — biophysics — Posted on 2022-09-28

487 Vesicles driven by dynein and kinesin exhibit directional reversals without external regulators

D'Souza, A. I.; Grover, R.; Monzon, G. A.; Santen, L.; Diez, S.

10.1101/2022.09.27.509758 — biophysics — Posted on 2022-09-28

488 Phylogenetic inference from single-cell RNA-seq data

Liu, X.; Griffiths, J. I.; Bishara, I.; Liu, J.; Bild, A. H.; Chang, J. T.

10.1101/2022.09.27.509725 — bioinformatics — Posted on 2022-09-28

489 MTG-Link: leveraging barcode information from linked-reads to assemble specific loci

Guichard, A.; Legeai, F.; TAGU, D.; Lemaitre, C.

10.1101/2022.09.27.509642 — bioinformatics — Posted on 2022-09-28

490 Structure-Based Pathogenicity Relationship Identifier (SPRI): A Novel Structure-Guided Method to Evaluate Pathological Effect of Missense Mutations

Wang, B.; Lei, X.; Tian, W.; Perez-Rathke, A.; Tseng, Y.-Y.; Liang, J.

10.1101/2022.09.27.508720 — bioinformatics — Posted on 2022-09-28

491 Batch Normalization Followed by Merging Is Powerful for Phenotype Prediction Integrating Multiple Heterogeneous Studies

Gao, Y.; Sun, F.

10.1101/2022.09.28.509843 — bioinformatics — Posted on 2022-09-28

492 A 1D Model Characterizing the Role of Spatiotemporal Contraction Distributions on Lymph Transport

Sedaghati, F.; Dixon, B.; gleason, R.

10.1101/2022.09.26.508881 — bioengineering — Posted on 2022-09-28

493 Development of Comprehensive Ultraperformance Liquid Chromatography-High Resolution Mass Spectrometry Assays to Quantitate Cisplatin-Induced DNA-DNA Cross-Links

Groehler, A. S.; Maratova, A.; Dao, N. M.; Makhmut, A.; Scharer, O. D.

10.1101/2022.09.28.509855 — biochemistry — Posted on 2022-09-28

494 FAM237A, rather than peptide PEN and proCCK56-63, is a ligand of the orphan receptor GPR83

Li, H.-Z.; Wang, Y.-F.; Shao, X.-X.; Liu, Y.-L.; Xu, Z.-G.; Wang, S.-L.; Guo, Z.-Y.

10.1101/2022.09.27.509696 — biochemistry — Posted on 2022-09-28

495 Competing females strategically combine signals and physical aggression differently from males in a polygynous tropical lizard

Ranade, D.; Karatgi, R.; Mahishi, S.; Isvaran, K.

10.1101/2022.09.27.508996 — animal behavior and cognition — Posted on 2022-09-28

496 Spatially Resolved Single-cell Translatomics at Molecular Resolution

Zeng, H.; Huang, J.; Ren, J.; Wang, C. K.; Tang, Z.; Zhou, Y.; Aditham, A.; Shi, H.; Sui, X.; Wang, X.

10.1101/2022.09.27.509605 — genomics — Posted on 2022-09-28

497 Vasoactive Endothelial Growth Factor and Heat Shock Protein Gene Expression Response in Kawasaki Disease Associated Coronary Arteritis

Rashid, A.; Malik, R.; Malik, Z.; Shaikh, G.; Hussain, Z.; Al-Dubai, A.; Hussain, A.

10.1101/2022.09.26.508411 — genomics — Posted on 2022-09-28

498 Adjusting for genetic confounders in transcriptome-wide association studies leads to reliable detection of causal genes

Zhao, S.; Crouse, W.; Qian, S.; Luo, K.; Stephens, M.; He, X.

10.1101/2022.09.27.509700 — genomics — Posted on 2022-09-28

499 Pollen contamination and mating structure in maritime pine (Pinus pinaster Ait.) clonal seed orchards revealed by SNP markers

Bouffier, L.; Debille, S.; Alazard, P.; Raffin, A.; Pastuszka, P.; Trontin, J.-F.

10.1101/2022.09.27.509769 — genetics — Posted on 2022-09-28

500 Edaphic specialization onto bare, rocky outcrops as a factor in the evolution of desert angiosperms

Lichter-Marck, I. H.; Baldwin, B. G.

10.1101/2022.09.27.509613 — evolutionary biology — Posted on 2022-09-28

501 Down the Penrose stairs: How selection for fewer recombination hotspots maintains their existence

Baker, Z.; Przeworski, M.; Sella, G.

10.1101/2022.09.27.509707 — evolutionary biology — Posted on 2022-09-28

502 Deep Learning from Phylogenies for Diversification Analyses

Lambert, S.; Voznica, J.; Morlon, H.

10.1101/2022.09.27.509667 — evolutionary biology — Posted on 2022-09-28

503 Rising novelty and homogenization of breeding bird communities in the U.S.

Latimer, C. E.; Graves, R.; Pidgeon, A. M.; Gorzo, J. M.; Henschell, M. M.; Schilke, P. R.; Hobi, M. L.; Olah, A.; Kennedy, C. M.; Zuckerberg, B.; Radeloff, V. C.

10.1101/2022.09.27.509749 — ecology — Posted on 2022-09-28

504 The clone wars: the Japanese knotweed (Fallopia japonica) vs the black vine weevil (Otiorhynchus sulcatus), characterization of a potential herbivory

TEULIER, L.; PUIJALON, S.; BOISSELET, C.; PIOLA, F.

10.1101/2022.09.27.509672 — ecology — Posted on 2022-09-28

505 Strong Ethanol- and Frequency-Dependent Ecological Interactions in a Community of Wine-Fermenting Yeasts

Lax, S.; Gore, J.

10.1101/2022.09.27.509741 — ecology — Posted on 2022-09-28

506 Multimodal mass spectrometry imaging reveals single-cell metabolic states in mammalian liver

Tian, H.; Rajbhandari, P. R.; Tarolli, J.; Decker, A. M.; Neelakantan, T. V.; Angerer, T.; Zandkarimi, F.; Daniels, J.; Remotti, H. R.; Frache, G.; Winograd, N.; Stockwell, B. R.

10.1101/2022.09.26.508878 — cell biology — Posted on 2022-09-28

507 Towards optimised extracellular vesicle proteomics from cerebrospinal fluid

Kangas, P.; Nyman, T. A.; Metsähonkala, L.; Burns, C.; Tempest, R.; Williams, T.; Karttunen, J.; Jokinen, T. S.

10.1101/2022.09.27.508990 — cell biology — Posted on 2022-09-28

508 Zinc-based Ultrasensitive Microscopic Barrier Assay (ZnUMBA): a live-imaging method for detecting epithelial barrier breaches with spatiotemporal precision

Higashi, T.; Stephenson, R. E.; Schwayer, C.; Huljev, K.; Heisenberg, C.-P.; Chiba, H.; Miller, A. L.

10.1101/2022.09.27.509705 — cell biology — Posted on 2022-09-28

509 KaryoCreate: a new CRISPR-based technology to generate chromosome-specific aneuploidy by targeting human centromeres

Bosco, N.; Goldberg, A.; Johnson, A. F.; Zhao, X.; Mays, J. C.; Cheng, P.; Bianchi, J. J.; Toscani, C.; Katsnelson, L.; Annuar, D.; Mei, S.; Faitelson, R. E.; Pesselev, I. Y.; Mohamed, K. S.; Mermerian, A.; Camacho-Hernandez, E. M.; Gionco, C. A.; Manikas, J.; Tseng, Y.-S.; Sun, Z.; Fani, S.; Keegan, S.; Lippman, S. M.; Fenyo, D.; Santaguida, S.; Davoli, T.

10.1101/2022.09.27.509580 — cell biology — Posted on 2022-09-28

510 Perplexity about periodicity repeats perpetually: A response to Brookshire

Re, D.; Tosato, T.; Fries, P.; Landau, A. N.

10.1101/2022.09.26.509017 — neuroscience — Posted on 2022-09-28

511 Vascular-water-exchange MRI (VEXI) enables the detection of subtle BBB breakdown in Alzheimer's disease without MRI contrast agent

Zhang, Y.; Wang, Y.; Li, Z.; Wang, Z.; Cheng, J.; Bai, X.; Hsu, Y.-C.; Sun, Y.; Li, S.; Shi, J.; Sui, B.; Bai, R.

10.1101/2022.09.27.509514 — neuroscience — Posted on 2022-09-28

512 Cannabidiol targets a modulatory system for excitatory-inhibitory synaptic coordination, contributing to its anti-seizure action

Rosenberg, E.; Chamberland, S.; Bazelot, M.; Nebet, E.; Wang, X.; McKenzie, S.; Jain, S.; Greenhill, S.; Wilson, M.; Salah, A.; Bailey, S.; Patra, P. H.; Chenouard, N.; Sun, S.; Jones, D.; Buzsaki, G.; Devinsky, O.; Woodhall, G.; Scharfman, H.; Whalley, B.; Tsien, R.

10.1101/2022.09.27.509638 — neuroscience — Posted on 2022-09-28

513 Heterologous boost with mRNA vaccines against SARS-CoV-2 Delta/Omicron variants following an inactivated whole-virus vaccine

Lu, C.; Zhang, Y.; Liu, X.; Hou, F.; Cai, R.; Yu, Z.; Liu, F.; Yang, G.; Ding, J.; Xu, J.; Hua, X.; Pan, X.; Liu, L.; Lin, K.; Wang, Z.; Li, X.; Lu, J.; Zhang, Q.; Li, Y.; Hu, C.; Fan, H.; Liu, X.; Wang, H.; Jia, R.; Xu, F.; Wang, X.; Huang, H.; Zhao, R.; Li, J.; Cheng, H.; Jia, W.; Yang, X.

10.1101/2022.09.06.506714 — molecular biology — Posted on 2022-09-28

514 Model-based whole-brain perturbational landscape of neurodegenerative diseases

Sanz Perl, Y.; Fittipaldi, S.; Gonzalez Campo, C.; Moguilner, S.; Cruzat, J.; Herzog, R.; Kringelbach, M. L.; Deco, G.; Prado, P.; Ibanez, A.; Tagliazucchi, E.

10.1101/2022.09.26.509612 — neuroscience — Posted on 2022-09-28

515 Age-associated sleep-wake patterns are altered with Prdm13 signaling in the dorsomedial hypothalamus and dietary restriction in mice

Tsuji, S.; Brace, C. S.; Yao, R.; Tanie, Y.; Tada, H.; Rensing, N.; Mizuno, S.; Almunia, J.; Kong, Y.; Nakamura, K.; Ogiso, N.; Toyokuni, S.; Takahashi, S.; Wong, M.; Imai, S.-i.; Satoh, A.

10.1101/2022.09.26.509442 — physiology — Posted on 2022-09-28

516 SARS-CoV-2 variants show temperature-dependent enhanced polymerase activity in the upper respiratory tract and high transmissibility

Kim, S.-M.; Kim, E.-H.; Casel, M. A. B.; Kim, Y.-i.; Sun, R.; Kwack, M.-J.; Yoo, J.-S.; Yoo, M.-A.; Yoo, K.-M.; Jang, S.-G.; Rollon, R.; Choi, J. H.; Gil, J.; Eun, K.; Kim, H.; Ensser, A.; Hwang, J.; Song, M.-S.; Kim, M. H.; Jung, J. U.; Choi, Y. K.

10.1101/2022.09.27.509689 — microbiology — Posted on 2022-09-28

517 Learning the action inventory of a complex skill via an intrinsic reward

Toutounji, H.; Zai, A. T.; Tchernichovski, O.; Hahnloser, R. H. R.; Lipkind, D.

10.1101/2022.09.27.509691 — animal behavior and cognition — Posted on 2022-09-28

518 HB-EGF promotes horizontal basal cell proliferation and olfactory sensory neuron regeneration in the zebrafish olfactory epithelium

Sireci, S.; Kocagöz, Y.; Alkiraz, A. S.; Güler, K.; Dokuzluoglu, Z.; Balcioglu, E.; Demirler, M. C.; Fuss, S. H.

10.1101/2022.09.26.509477 — developmental biology — Posted on 2022-09-28

519 Lysosome repair by ER-mediated cholesterol transfer

Radulovic, M.; Wenzel, E. M.; Gilani, S.; Holland, L. K. K.; Lystad, A. H.; Phuyal, S.; Olkkonen, V. M.; Brech, A.; Jäättelä, M.; Maeda, K.; Raiborg, C.; Stenmark, H.

10.1101/2022.09.26.509457 — cell biology — Posted on 2022-09-28

520 The assembly of wild natural isolates define neuronal integrity and life history traits of co-inhabiting C. elegans.

Urquiza-Zurich, S.; Garcia-Angulo, V. A.; Burdisso, P.; Palominos, M. F.; Fernandez-Hubeid, L.; Castillo, J. P.; Calixto, A.

10.1101/2022.09.26.509631 — microbiology — Posted on 2022-09-28

521 Cell circuits between leukemic cells and mesenchymal stem cells block lymphopoiesis by activating lymphotoxin-beta receptor signaling

Feng, X.; Sun, R.; Lee, M.; Chen, X.; Guo, S.; Geng, H.; Müschen, M.; Choi, J.; Pereira, J. P.

10.1101/2022.09.23.509256 — immunology — Posted on 2022-09-28

522 A Multivalent Polyomavirus Vaccine Elicits Durable Neutralizing Antibody Responses in Macaques

Peretti, A.; Scorpio, D. G.; Kong, W.-P.; Pang, Y.-Y. S.; McCarthy, M. P.; Ren, K.; Jackson, M.; Graham, B. S.; Buck, C. B.; McTamney, P. M.; Pastrana, D. V.

10.1101/2022.09.26.509096 — immunology — Posted on 2022-09-28

523 Exploring the role of the outer subventricular zone during cortical folding through a physics-based model

Zarzor, M. S.; Blumcke, I.; Budday, S.

10.1101/2022.09.25.509401 — neuroscience — Posted on 2022-09-28

524 DNA methylation at a single cytosine embedded in the W-box cis-element repels binding of WRKY transcription factors through steric hindrance

Charvin, M.; Halter, T.; Blanc-Mathieu, R.; Barraud, P.; Aumont-Nicaise, M.; Parcy, F.; Navarro, L.

10.1101/2022.09.26.509487 — plant biology — Posted on 2022-09-28

525 GOLVEN peptides regulate lateral root spacing as part of a negative feedback loop on the establishment of auxin maxima

Jourquin, J.; Fernandez, A. I.; Xu, K.; Simura, J.; Ljung, K.; Beeckman, T.

10.1101/2022.09.26.509595 — plant biology — Posted on 2022-09-28

526 The fitness of an introgressing haplotype

Dagilis, A. J.; Matute, D. R.

10.1101/2022.09.27.507129 — evolutionary biology — Posted on 2022-09-28

527 Kazrin is an endosomal adaptor for dynein/dynactin

Hernandez-Perez, I.; Baumann, A.; Rubio, J.; Girao, H.; Rebollo, E.; Aragay, A. M.; Geli, M. I.

10.1101/2021.08.30.458243 — cell biology — Posted on 2022-09-28

528 Alternative mRNA polyadenylation bridges mitochondrion-to-nucleus communication in Arabidopsis

Jia, H.; Zeng, W.; Zhang, X.; Li, J.; Bao, X.; Zhao, Y.; Zhu, L.; Ma, C.; Wang, F.; Guo, X.; Song, C.-P.; Ma, L.; Zhu, X.

10.1101/2022.09.27.509730 — molecular biology — Posted on 2022-09-28

529 Genome-wide co-essentiality analysis in Mycobacterium tuberculosis reveals an itaconate defense enzyme module

Jinich, A.; Nazia, S. Z.; Tellez, A. V.; Wu, A. M.; Smith, C. M.; Rhee, K. Y.

10.1101/2022.09.27.509804 — microbiology — Posted on 2022-09-28

530 In vivo proximity ligation reveals endogenous candidate interactors of Neurexin's intracellular domain

Schaan Profes, M.; Tiroumalechetty, A.; Patel, N.; Lauar, S. S.; Sidoli, S.; Kurshan, P.

10.1101/2022.09.27.509791 — neuroscience — Posted on 2022-09-28

531 FOXP1 orchestrates neurogenesis in human cortical basal radial glial cells

Park, S. H. E.; Kulkarni, A.; Konopka, G.

10.1101/2022.09.28.509837 — neuroscience — Posted on 2022-09-28

532 The maternal brain is more flexible and responsive at rest: effective connectivity of the parental caregiving network in postpartum mothers

Orchard, E. R.; Voigt, K.; Chopra, S.; Thapa Rana, T.; Ward, P. G.; Egan, G. F.; Jamadar, S. D.

10.1101/2022.09.26.509524 — neuroscience — Posted on 2022-09-28

533 Iterative immunostaining combined with expansion microscopy and image processing reveals nanoscopic network organization of nuclear lamina

Mantyla, E.; Montonen, T.; Azzari, L.; Mattola, S.; Hannula, M.; Vihinen-Ranta, M.; Hyttinen, J.; Vippola, M.; Foi, A.; Nymark, S.; Ihalainen, T. O.

10.1101/2022.09.27.509734 — molecular biology — Posted on 2022-09-28

534 The RNA binding proteins ZFP36L1 and ZFP36L2 modulate transcriptional and post-transcriptional genome-wide effects of glucocorticoids

Rynne, J.; Ortiz-Zapater, E.; Khooshemehri, P.; Ponde, N. O.; Bucca, G.; Hesketh, A.; Plate, M.; Chambers, R.; Smith, C. P.; Martinez-Nunez, R. T.

10.1101/2022.09.27.509553 — molecular biology — Posted on 2022-09-28

535 Molecular tools for early detection of invasion of malaria vector Anopheles stephensi

Singh, O. P.; Kaur, T.; Sharma, G.; Prasad, K. M.; Kapoor, N.; Mallick, P. K.

10.1101/2022.09.26.509490 — molecular biology — Posted on 2022-09-28

536 The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress

Meydan, S.; Barros, G.; Simoes, V.; Harley, L.; Cizubu, B. K.; Guydosh, N. R.; Silva, G.

10.1101/2022.09.27.509727 — molecular biology — Posted on 2022-09-28

537 AGAL misprocessing-induced ER stress and the unfolded protein response: lysosomal storage-independent mechanism of Fabry disease pathogenesis?

Zivna, M.; Dostalova, G.; Baresova, V.; Musalkova, D.; Kuchar, L.; Asfaw, B.; Poupetova, H.; Vlaskova, H.; Kmochova, T.; Vyletal, P.; Hartmannova, H.; Hodanova, K.; Stranecky, V.; Steiner-Mrazova, L.; Hnizda, A.; Radina, M.; Votruba, M.; Sovova, J.; Treslova, H.; Stolnaja, L.; Rekova, P.; Roblova, L.; Honsova, E.; Hulkova, H.; Rychlik, I.; Bleyer, A. J.; Linhart, A.; Sikora, J.; Kmoch, S.

10.1101/2022.09.27.509714 — molecular biology — Posted on 2022-09-28

538 The TaxUMAP atlas: efficient display of large clinical microbiome data reveals ecological competition involved in protection against bacteremia

Schluter, J.; Djukovic, A.; Taylor, B. P.; Yan, J.; Duan, C.; Hussey, G. A.; Liao, C.; Sharma, S.; Fontana, E.; Amoretti, L. A.; Wright, R. J.; Dai, A.; Peled, J.; Taur, Y.; Perales, M.-A.; Siranosian, B. A.; Bhatt, A. S.; van den Brink, M. R. M.; Pamer, E. G.; Xavier, J. B.

10.1101/2022.09.27.509746 — microbiology — Posted on 2022-09-28

539 Bordetella spp. block eosinophil recruitment to suppress lung iBALT formation

First, N. J.; Martinez, A.; Gonzalez-Fernandez, A.; Bharrhan, S.; Roan, C.; Cox, E.; Wang, J.; Scott, R.; Woolard, M.; Gestal, M. C.

10.1101/2022.09.27.509784 — microbiology — Posted on 2022-09-28

540 Characterization of membrane vesicles in Alteromonas macleodii indicates potential roles in their copiotrophic lifestyle

Fadeev, E.; Carpaneto Bastos, C.; Hennenfeind, J.; Biller, S. J.; Sher, D. J.; Wietz, M.; Herndl, G. J.

10.1101/2022.09.27.509651 — microbiology — Posted on 2022-09-28

541 Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a point mutation in adenylate cyclase with drastic tradeoffs for pathogenicity

Hilbert, Z.; Chung, K.; Bednarek, J.; Schwiesow, M.; Brown, J. C. S.; Elde, N. C.

10.1101/2022.09.27.509772 — microbiology — Posted on 2022-09-28

542 Single-cell resolution genetic association analysis of heterogeneous bacterial communities by utilizing droplet digital PCR

Dutra, L. A. L.; Jalasvuori, M.; Franz, O.; Nurminen, K.; Salmi, P.; Tiirola, M.; Penttinen, R.

10.1101/2022.09.27.509627 — microbiology — Posted on 2022-09-28

543 Combinatorial control of biofilm development by quorum-sensing and nutrient-sensing regulators.

Chen, G.; Lim, E. D.; Winkelman, B. T.; Winkelman, J. T.; Mukherjee, S.

10.1101/2022.09.27.509822 — microbiology — Posted on 2022-09-28

544 An automated microscopy workflow to study Shigella-neutrophil interactions and antibiotic efficacy in vivo

Lensen, A.; Gomes, M. C.; Lopez-Jimenez, A. T.; Mostowy, S.

10.1101/2022.09.27.509710 — microbiology — Posted on 2022-09-28

545 Cyclitol secondary metabolism is a central feature of Burkholderia leaf symbionts

Danneels, B.; Blignaut, M.; Marti, G.; Sieber, S.; Vandamme, P.; Meyer, M.; Carlier, A.

10.1101/2022.09.27.509721 — microbiology — Posted on 2022-09-28

546 Influenza A virus reassortment is strain dependent

Taylor, K. Y.; Agu, I.; Jose, I. R.; Mantynen, S.; Campbell, A. J.; Mattson, C.; Chou, T.-w.; Zhou, B.; Gresham, D.; Ghedin, E.; Diaz-Munoz, S. L.

10.1101/2022.09.26.509616 — microbiology — Posted on 2022-09-28

547 Can genomics and meteorology predict outbreaks of legionellosis in urban settings?

Timms, V. J.; Sim, E.; Pey, K.; Sintchenko, V.

10.1101/2022.09.26.509626 — microbiology — Posted on 2022-09-28

548 Copper stress perturbs zinc and manganese homeostasis in Streptococcus pyogenes.

Hong, Y. J.; Mackenzie, E. S.; Firth, S. J.; Bolton, J. F.; Stewart, L. J.; Waldron, K. J.; Djoko, K. Y.

10.1101/2022.09.28.509676 — microbiology — Posted on 2022-09-28

549 Biochemical identification of a nuclear coactivator protein required for AtrR-dependent gene regulation in Aspergillus fumigatus

Paul, S.; Ror, S.; McDonald, W. H.; Moye-Rowley, W. S.

10.1101/2022.09.26.509624 — microbiology — Posted on 2022-09-28

550 Excessive fluid shear stress-mediated Klf4 leads to arteriovenous pathogenesis

Banerjee, K.; Gahn, J.; Lin, Y.; Lei, X.; Gupta, P.; Graupera, M.; Schwartz, M. A.; Ola, R.

10.1101/2022.07.04.498236 — molecular biology — Posted on 2022-09-28

551 Towards In-Silico CLIP-seq: Predicting Protein-RNA Interaction via Sequence-to-Signal Learning

Horlacher, M.; Wagner, N.; Moyon, L.; Kuret, K.; Goedert, N.; Salvatore, M.; Ule, J.; Gagneur, J.; Winther, O.; Marsico, A.

10.1101/2022.09.16.508290 — bioinformatics — Posted on 2022-09-28

552 The Divergence of Mean Phenotypes Under Persistent Directional Selection

Devi, A.; Speyer, G.; Lynch, M.

10.1101/2022.09.27.509694 — evolutionary biology — Posted on 2022-09-28

553 DOT1L interaction partner AF10 controls patterning of H3K79 methylation to maintain cell identity

Wille, C. K.; Neumann, E. N.; Deshpande, A. J.; Sridharan, R.

10.1101/2020.12.17.423347 — developmental biology — Posted on 2022-09-28

554 Transcription factors interact with RNA to regulate genes

Oksuz, O.; Henninger, J. E.; Warneford-Thomson, R.; Zheng, M. M.; Erb, H.; Overholt, K. J.; Hawken, S. W.; Banani, S. F.; Lauman, R.; Vancura, A.; Robertson, A. L.; Hannett, N. M.; Lee, T.; Zon, L. I.; Bonasio, R.; Young, R. A.

10.1101/2022.09.27.509776 — molecular biology — Posted on 2022-09-28

555 Goal-directed vocal planning in a songbird

Zai, A. T.; Stepien, A. E.; Cave-Lopez, S.; Giret, N.; Hahnloser, R. H. R.

10.1101/2022.09.27.509747 — neuroscience — Posted on 2022-09-28

556 Maturational networks of fetal brain activity

Karolis, V. R.; Fitzgibbon, S. P.; Cordero-Grande, L.; Farahibozorg, S.-R.; Price, A. N.; Hughes, E. J.; Fetit, A. E.; Kyriakopoulou, V.; Pietsch, M.; Rutherford, M.; Rueckert, D.; Hajnal, J. V.; Edwards, A. D.; O'Muircheartaigh, J.; Duff, E.; Arichi, T.

10.1101/2022.06.14.495883 — neuroscience — Posted on 2022-09-28

557 Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Bridi, M.; Luo, N.; Kim, G.; O'Ferrall, C.; Oatel, R.; Bertrand, S.; Kannan, S.; Kirkwood, A.

10.1101/2021.07.05.451213 — neuroscience — Posted on 2022-09-28

558 Developmental trajectories of the default mode, executive control, and salience networks from the third trimester through the newborn period

Scheinost, D.; Chang, J.; Brennan-Wydra, E.; Lacadie, C.; Constable, R. T.; Chawarska, K.; Ment, L. R.

10.1101/2022.09.27.509687 — neuroscience — Posted on 2022-09-28

559 Rapid profiling of protein complex re-organization in perturbed systems

Bludau, I.; Nicod, C.; Martelli, C.; Xue, P.; Heusel, M.; Fossati, A.; Uliana, F.; Frommelt, F.; Aebersold, R.; Collins, B. C.

10.1101/2021.12.17.473177 — systems biology — Posted on 2022-09-28

560 Ecological interactions in breast cancer: Cell facilitation promotes growth and survival under drug pressure

Emond, R.; Griffiths, J. I.; Grolmusz, V. K.; Nath, A.; Chen, J.; Medina, E. F.; Sousa, R. S.; Adler, F. R.; Bild, A. H.

10.1101/2021.02.01.429214 — systems biology — Posted on 2022-09-28

561 Chloroplasts in plant cells show active glassy behavior under low light conditions

Schramma, N.; Perugachi Israëls, C.; Jalaal, M.

10.1101/2022.04.15.488438 — biophysics — Posted on 2022-09-28

562 Spurious off-target signals from potential lncRNAs by 10X Visium probes

Prakrithi, P.; Sami, J.; Jain, D.; Malik, P. S.; Gupta, I.

10.1101/2022.09.25.509336 — bioinformatics — Posted on 2022-09-28

563 A Multivariate Approach to Understanding the Genetic Overlap between Externalizing Phenotypes and Substance Use Disorders

Poore, H. E.; Hatoum, A.; Mallard, T. T.; Sanchez-Roige, S.; Waldman, I. D.; Palmer, A. A.; Harden, K. P.; Barr, P. B.; Dick, D. M.

10.1101/2022.09.27.509777 — genetics — Posted on 2022-09-28

564 Effects of α-crystallin gene knockout on zebrafish lens development

Posner, M.; Murray, K. L.; Andrew, B.; Brdicka, S.; Butterbaugh-Roberts, A.; Franklin, K.; Hussen, A.; Kaye, T.; Kepp, E.; McDonald, M. S.; Snodgrass, T.; Zientek, K.; David, L. L.

10.1101/2021.12.22.473921 — developmental biology — Posted on 2022-09-28

565 Microtubule-mitochondrial attachmentfacilitates cell division symmetry and propermitochondrial partitioning in fission yeast

Chacko, L. A.; Mikus, F.; Ariotti, N.; Dey, G.; Ananthanarayanan, V.

10.1101/2021.12.19.473396 — cell biology — Posted on 2022-09-28

566 Twist1 and balanced retinoic acid signaling act to suppress cortical folding in mice

Ho-Nguyen, K.-T.; Jain, M.; Matrongolo, M. J.; Ang, P. S.; Schaper, S.; Tischfield, M. A.

10.1101/2022.09.27.509818 — neuroscience — Posted on 2022-09-28

567 The Uniqueness of Human Vulnerability to Brain Aging in Great Ape Evolution

Vickery, S.; Patil, K. R.; Dahnke, R.; Hopkins, W. D.; Sherwood, C. C.; Caspers, S.; Eickhoff, S. B.; Hoffstaedter, F.

10.1101/2022.09.27.509685 — neuroscience — Posted on 2022-09-28

568 Intrinsic neural timescales in the temporal lobe support an auditory processing hierarchy

Cusinato, R.; Alnes, S. L.; van Maren, E.; Boccalaro, I.; Ledergerber, D.; Adamantidis, A.; Imbach, L. L.; Schindler, K.; Baud, M. O.; Tzovara, A.

10.1101/2022.09.27.509695 — neuroscience — Posted on 2022-09-28

569 The development of compulsive coping behaviors depends on the engagement of dorsolateral striatum dopamine-dependent mechanisms

Giuliano, C.; Marti-Prats, L.; Domi, A.; Puaud, M.; Pena-Oliver, Y.; McKenzie, C.; Everitt, B. J.; Belin, D.

10.1101/2022.09.27.509680 — neuroscience — Posted on 2022-09-28

570 Interneuron-targeted disruption of SYNGAP1 alters sensory representations in neocortex and impairs sensory learning

Kwon, S. E.; Zhao, M.

10.1101/2022.09.27.509690 — neuroscience — Posted on 2022-09-28

571 MAVEN: Compound mechanism of action analysis and visualisation using transcriptomics and compound structure data in R/Shiny

Hosseini-Gerami, L.; Hernansaiz Ballesteros, R.; Liu, A.; Broughton, H.; Collier, D. A.; Bender, A.

10.1101/2022.07.20.500792 — systems biology — Posted on 2022-09-28

572 Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation

Cheng, A.; Kawahata, I.; Wang, Y.; Jia, W.; Sekimori, T.; Chen, Y.; Stefanova, N.; Finkelstein, D. I.; Ma, W.; Chen, M.; Sasaki, T.; Fukunaga, K.

10.1101/2022.06.16.496509 — pathology — Posted on 2022-09-28

573 HMMploidy: inference of ploidy levels from short-read sequencing data

Soraggi, S.; Rhodes, J.; Altinkaya, I.; Tarrant, O.; Balloux, F.; Fisher, M. C.; Fumagalli, M.

10.1101/2021.06.29.450340 — bioinformatics — Posted on 2022-09-27

574 Identification of potential human pancreatic α-amylase inhibitors from natural products by molecular docking, MM/GBSA calculations, MD simulations, and ADMET analysis

Basnet, S.; Ghimire, M. P.; Lamichhane, T. R.; Adhikari, R.; Adhikari, A.

10.1101/2022.09.26.509544 — bioinformatics — Posted on 2022-09-28

575 External validation and further exploration of fall prediction models based on questionnaires and daily-life trunk accelerometry

Zhang, Y.; Weijer, R.; Schooten, K. v.; Bruijn, S. M.; Pijnappels, M.

10.1101/2022.09.26.509506 — bioengineering — Posted on 2022-09-27

576 A novel mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteoclastogenic effects of breast cancer cells

Kumar, V.; Naqvi, S. M.; VERBRUGGEN, A.; McEvoy, E.; McNamara, L.

10.1101/2022.09.19.508588 — bioengineering — Posted on 2022-09-27

577 The evolution and biological correlates of hand preferences in anthropoid primates

Caspar, K. R.; Pallasdies, F.; Mader, L.; Sartorelli, H.; Begall, S.

10.1101/2021.12.30.474462 — animal behavior and cognition — Posted on 2022-09-28

578 Tyramine and its AmTYR1 receptor modulate attention in honey bees (Apis mellifera)

Latshaw, J. S.; Mazade, R. E.; Petersen, M.; Mustard, J. A.; Sinakevitch, I.; Wissler, L.; Guo, X.; Cook, C. N.; Lei, H.; Gadau, J.; Smith, B. H.

10.1101/2022.09.02.506392 — animal behavior and cognition — Posted on 2022-09-28

579 Evolutionary responses of energy metabolism, development, and reproduction to artificial selection for increasing heat tolerance in Drosophila subobscura

Mesas, A.; Castaneda, L. E.

10.1101/2022.02.03.479001 — evolutionary biology — Posted on 2022-09-27

580 CorA gene rearrangement triggered the salinity-driven speciation of Poseidoniales

Fan, L.; Xu, B.; Chen, S.; Liu, Y.; Li, F.; Xie, W.; Prabhu, A.; Zou, D.; Wan, R.; Li, H.; Liu, H.; Liu, Y.; Kao, S.-J.; Chen, J.; Zhu, Y.; Rinke, C.; Li, M.; Zhang, C.

10.1101/2022.09.25.509439 — evolutionary biology — Posted on 2022-09-27

581 Inferring sparse structure in genotype-phenotype maps

Petti, S.; Reddy, G.; Desai, M. M.

10.1101/2022.09.27.509675 — evolutionary biology — Posted on 2022-09-27

582 Hummingbird blood traits track oxygen availability across space and time

Williamson, J. L.; Linck, E. B.; Bautista, E.; Smiley, A.; McGuire, J. A.; Dudley, R.; Witt, C. C.

10.1101/2022.01.18.476833 — evolutionary biology — Posted on 2022-09-28

583 A self-blinking DNA probe for live-cell 3D imaging of native chromatin

ZHENG, Y.; Ye, S.; Li, S.; Liu, C.; Luo, S.; Chen, Y.; Li, Y.; Huang, L.; Deng, S.; Chen, P.; Zhang, Y.; Ji, W.; Luo, R.; Li, G.; Yang, D.

10.1101/2022.06.22.497271 — cell biology — Posted on 2022-09-28

584 A novel, ssDNA Bidnavirus in the giant freshwater prawn Macrobrachium rosenbergii

Gangnonngiw, W.; Bunnontae, M.; Kayansamruaj, P.; Senapin, S.; Srisala, J.; Flegel, T. W.; Wongprasert, K.

10.1101/2022.09.25.509311 — microbiology — Posted on 2022-09-27

585 Evolution within a given virulence phenotype (pathotype) is driven by changes in aggressiveness: a case study of French wheat leaf rust populations

FONTYN, C.; MEYER, K. J.; BOIXEL, A.-L.; DELESTRE, G.; PIAGET, E.; PICARD, C.; SUFFERT, F.; MARCEL, T. C.; GOYEAU, H.

10.1101/2022.08.29.505401 — microbiology — Posted on 2022-09-27

586 Speech imagery decoding as a window to speech planning and production

Orpella, J.; Mantegna, F.; Assaneo, F.; Poeppel, D.

10.1101/2022.05.30.494046 — neuroscience — Posted on 2022-09-27

587 Structural and thermodynamic analyses of the β-to-α transformation in RfaH reveal principles of fold-switching proteins

Zuber, P. K.; Daviter, T.; Heissmann, R.; Persau, U.; Schweimer, K.; Knauer, S. H.

10.1101/2022.01.14.476317 — biophysics — Posted on 2022-09-27

588 Rethinking Margin of Stability: Incorporating Step-To-Step Regulation to Resolve the Paradox

Kazanski, M. E.; Cusumano, J. P.; Dingwell, J. B.

10.1101/2021.12.01.470263 — bioengineering — Posted on 2022-09-27

589 A 16p11.2 deletion mouse model displays quantitatively and qualitatively different behaviours in sociability and social novelty over short- and long-term observation.

Rusu, A.; Chevalier, C.; de Chaumont, F.; Nalesso, V.; Brault, V.; Herault, Y.; Ey, E.

10.1101/2022.09.16.508234 — animal behavior and cognition — Posted on 2022-09-27

590 ModelRevelator: Fast phylogenetic model estimation via deep learning

Burgstaller-Muehlbacher, S.; Crotty, S. M.; Schmidt, H. A.; Drucks, T.; von Haeseler, A.

10.1101/2021.12.22.473813 — evolutionary biology — Posted on 2022-09-27

591 Urbanisation impacts plumage colouration in a songbird across Europe: evidence from a correlational, experimental, and meta-analytical approach

Salmon, P.; Lopez-Idiaquez, D.; Capilla-Lasheras, P.; Perez-Tris, J.; Isaksson, C.; Watson, H.

10.1101/2022.09.13.507844 — evolutionary biology — Posted on 2022-09-27

592 SARS-CoV-2 variants show temperature-dependent enhancedpolymerase activity in the upper respiratory tract and high transmissibility

10.1101/2022.09.27.509689 — microbiology — Posted on 2022-09-27

593 Distinct replay signatures for prospective decision-making and memory preservation

Wimmer, G. E.; Liu, Y.; McNamee, D.; Dolan, R.

10.1101/2021.11.08.467745 — neuroscience — Posted on 2022-09-27

594 Spatiotemporally resolved transcriptomics reveals subcellular RNA kinetic landscape

Ren, J.; Zhou, H.; Zeng, H.; Wang, C. K.; Huang, J.; Qiu, X.; Maher, K.; Lin, Z.; He, Y.; Tang, X.; Li, B.; Liu, J.; Wang, X.

10.1101/2022.09.27.509606 — genomics — Posted on 2022-09-27

595 Nuclear translocation of spike mRNA and protein is a novel pathogenic feature of SARS-CoV-2.

Sattar, S.; Kabat, J.; Jerome, K.; Feldmann, F.; Bailey, K.; Mehedi, M.

10.1101/2022.09.27.509633 — microbiology — Posted on 2022-09-27

596 The structure of monkeypox virus 2'-O-ribose methyltransferase VP39 in complex with sinefungin provides the foundation for inhibitor design

Silhan, J.; Klima, M.; Chalupska, D.; Kozic, J.; Boura, E.

10.1101/2022.09.27.509668 — microbiology — Posted on 2022-09-27

597 Wild red deer (Cervus elaphus) do not play a role as vectors or reservoirs of SARS-CoV-2 in north-eastern Poland.

Krupinska, M.; Borkowski, J.; Goll, A.; Nowicka, J.; Baranowicz, K.; Bourret, V.; Strandin, T.; Maki, S.; Kant, R.; Sironen, T.; Grzybek, M.

10.1101/2022.09.27.509682 — microbiology — Posted on 2022-09-27

598 Context-dependent requirement of G protein coupling for Latrophilin-2 in target selection of hippocampal axons

Pederick, D. T.; Perry-Hauser, N. A.; Meng, H.; He, Z.; Javitch, J. A.; Luo, L.

10.1101/2022.09.26.509559 — developmental biology — Posted on 2022-09-27

599 Parafoveal semantic integration in natural reading

Pan, Y.; Frisson, S.; Federmeier, K. D.; Jensen, O.

10.1101/2022.09.26.509511 — neuroscience — Posted on 2022-09-27

600 Concurrent measurement of perfusion parameters related to small blood and lymphatic vessels in the human brain using dynamic dual-spin-echo perfusion (DDSEP) MRI

Cao, D.; Sun, Y.; Su, P.; Pillai, J. J.; Qiao, Y.; Lu, H.; Van Zijl, P. C. M.; Knutsson, L.; Hua, J.

10.1101/2022.09.26.509366 — neuroscience — Posted on 2022-09-27

601 Cross-species predictive modeling reveals conserved drought responses between maize and sorghum

Pardo, J.; Wai, C. M.; Harman, M.; Nguyen, A.; Kremling, K. A.; Romay, C.; Lepak, N.; Bauerle, T. L.; Buckler, E. S.; Thompson, A. M.; VanBuren, R.

10.1101/2022.09.26.509573 — plant biology — Posted on 2022-09-27

602 Genome-scale mRNA transcriptomic insights into the mature growth dynamic of Cigar tobacco leaves

Yang, J.; Wan, D.; Qiao, B.; Yu, J.; Li, Z.; Liu, D.; Lv, P.; Hu, J.; Rao, X.; Xu, F.; wang, s.; Yang, C.

10.1101/2022.09.26.509548 — plant biology — Posted on 2022-09-27

603 In vitro to in vivo pharmacokinetic translation guidance

Fagerholm, U.

10.1101/2022.09.26.509470 — pharmacology and toxicology — Posted on 2022-09-27

604 DepLink: an R Shiny app to systematically link genetic and pharmacologic dependencies of cancer

Nayak, T.; Wang, L.-J.; Ning, M.; Rubannelsonkumar, G.; Jin, E.; Zheng, S.; Houghton, P. J.; Huang, Y.; Chiu, Y.-C.; Chen, Y.

10.1101/2022.09.26.509353 — bioinformatics — Posted on 2022-09-27

605 Impact of phylogeny on structural contact inference from protein sequence data

Dietler, N.; Lupo, U.; Bitbol, A.-F.

10.1101/2022.09.26.509588 — bioinformatics — Posted on 2022-09-27

606 Chronic inflammation partially recapitulates the gene expression signature of aging

Landsberger, T.; Amit, I.; Alon, U.

10.1101/2022.09.26.509471 — bioinformatics — Posted on 2022-09-27

607 Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme

Pitino, M.; Fleites, L. A.; Shrum, L.; Heck, M.; Shatters, R. G.

10.1101/2022.09.03.506425 — bioengineering — Posted on 2022-09-27

608 Continuous transcriptome analysis reveals novel patterns of early gene expression in Drosophila embryos.

Perez-Mojica, J. E.; Enders, L.; Walsh, J.; Lau, K.; Lempradl, A.

10.1101/2022.09.26.509035 — genomics — Posted on 2022-09-27

609 Efficient CRISPR/Cas9 mediated large insertions using long single-stranded oligonucleotide donors in C. elegans

Eroglu, M.; Yu, B.; Derry, W. B.

10.1101/2022.09.26.509570 — genetics — Posted on 2022-09-27

610 Molecular genetics of GLUT1DS Italian pediatric cohort: 10 novel related-disease variants and structural analysis

Mauri, A.; Duse, A.; Palm, G.; Previtali, R.; Bova, S. M.; Olivotto, S.; Benedetti, S.; Coscia, F.; Veggiotti, P.; Cereda, C.

10.1101/2022.09.26.509448 — genetics — Posted on 2022-09-27

611 Complex plumages spur rapid color diversification in island kingfishers (Aves: Alcedinidae)

Eliason, C.; McCullough, J.; Hackett, S. J.; Andersen, M. J.

10.1101/2022.09.26.509475 — evolutionary biology — Posted on 2022-09-27

612 Seasonal models reveal niche changes in Capsella bursa-pastoris

Wilson Brown, M.; Josephs, E.

10.1101/2022.09.26.509568 — ecology — Posted on 2022-09-27

613 Integrated Model of the Vertebrate Augmin Complex

Travis, S. M.; Mahon, B. P.; Huang, W.; Ma, M.; Rale, M. J.; Kraus, J. S.; Taylor, D.; Zhang, R.; Petry, S.

10.1101/2022.09.26.509603 — molecular biology — Posted on 2022-09-27

614 Venom protection by antibody from a snakebite hyperimmune subject

Glanville, J.; Andrade, J. C.; Bellin, M.; Kim, S.; Pletnev, S.; Tsao, D.; Verardi, R.; Bedi, R.; Friede, T.; Liao, S.; Newland, R.; Bayless, N. L.; Youssef, S.; Tully, E.; Zhang, B.; Bylund, T.; Kim, S.; Liu, T.; Kwong, P. D.

10.1101/2022.09.26.507364 — immunology — Posted on 2022-09-27

615 Prototyping of a lateral flow assay based on monoclonal antibodies for detection of Bothrops venoms

Knudsen, C.; Jürgensen, J. A.; Knudsen, P. D.; Oganesyan, I.; Harrison, J. A.; Dam, S. H.; Haack, A. M.; Friis, R. U. W.; Belfakir, S. B.; Ross, G. M. S.; Zenobi, R.; Laustsen, A. H.

10.1101/2022.09.26.509137 — immunology — Posted on 2022-09-27

616 The promiscuous development of an unconventional Qa1b-restricted T cell population

Manoharan Valerio, M. A.; Arana, K.; Guan, J.; Wei Chan, S.; Kurd, N. S.; Lee, A.; Shastri, N.; Robey, E.

10.1101/2022.09.26.509583 — immunology — Posted on 2022-09-27

617 Structural conservation of Lassa virus glycoproteins and recognition by neutralizing antibodies

Perrett, H. R.; Brouwer, P. J. M.; Hurtado, J.; Newby, M. L.; Burger, J. A.; Liu, L.; Bouhuijs, J. H.; Gibson, G.; Messmer, T.; Schieffelin, J. S.; Antanasijevic, A.; Boons, G.-J.; Crispin, M.; Sanders, R. W.; Briney, B.; Ward, A. B.

10.1101/2022.09.26.509601 — immunology — Posted on 2022-09-27

618 Clinical, socio-demographic, and parental correlates of early autism traits

Gale-Grant, O.; Chew, A.; Falconer, S.; Franca, L. G. S.; Fenn-Moltu, S.; Hadaya, L.; Harper, N.; Ciarrusta, J.; Charman, T.; Murphy, D.; Arichi, T.; McAlonan, G.; Nosarti, C.; Edwards, D.; Batalle, D.

10.1101/2022.09.26.508121 — neuroscience — Posted on 2022-09-27

619 A highly expressed odorant receptor from the yellow fever mosquito, AaegOR11, responds to (+)- and (-)-fenchone and a phenolic repellent

Lu, W.; LEAL, W. S.; Brisco, K. K.; An, S.; Cornel, A. J.

10.1101/2022.09.26.509539 — neuroscience — Posted on 2022-09-27

620 Thalamocortical boutons cluster by ON/OFF responses in mouse primary visual cortex

Tring, E.; Ringach, D.

10.1101/2022.09.26.509569 — neuroscience — Posted on 2022-09-27

621 Targeting neuroinflammatory pathways using Nanoligomer is neuroprotective in prion disease

Risen, S. J.; Boland, S.; Sharma, S.; Weismann, G.; Shirley, P.; Hines, A. D.; Hay, A. J. D.; McGrath, S.; Chatterjee, A.; Nagpal, P.; Moreno, J. A.

10.1101/2022.09.26.509513 — neuroscience — Posted on 2022-09-27

622 EEG-neurofeedback for promoting neuromodulation in the elderly: evidence from a double-blind study

Andrade, K.; Guieysse, T.; Razafimahatratra, S.; Houmani, N.; Klarsfeld, A.; Dreyfus, G.; Dubois, B.; Medani, T.; Vialatte, F.

10.1101/2022.09.26.509227 — neuroscience — Posted on 2022-09-27

623 Primate pre-arcuate cortex actively maintains persistent representations of saccades from plans to outcomes

Calangiu, I.; Kollmorgen, S.; Reppas, J.; Mante, V.

10.1101/2022.09.26.509463 — neuroscience — Posted on 2022-09-27

624 Covariance-based Decoding Reveals Content-specific Feature Integration and Top-down Processing for Imagined Faces versus Places

Mantegna, F.; Olivetti, E.; Schwedhelm, P.; Baldauf, D.

10.1101/2022.09.26.509536 — neuroscience — Posted on 2022-09-27

625 Preserved neural population dynamics across animals performing similar behaviour

Safaie, M.; Chang, J. C.; Park, J.; Miller, L. E.; Dudman, J. T.; Perich, M. G.; Gallego, J. A.

10.1101/2022.09.26.509498 — neuroscience — Posted on 2022-09-27

626 Contrary neuronal recalibration in different multisensory cortical areas

Zeng, F.; Zaidel, A.; Chen, A.

10.1101/2022.09.26.509476 — neuroscience — Posted on 2022-09-27

627 Investigating the ability of astrocytes to drive neural network synchrony

Handy, G.; Borisyuk, A.

10.1101/2022.09.26.508928 — neuroscience — Posted on 2022-09-27

628 Evaluating user experience with immersive technology in simulation-based education: a modified Delphi study with qualitative analysis

Jacobs, C.; Foote, G.; Williams, M.

10.1101/2022.09.26.509545 — scientific communication and education — Posted on 2022-09-27

629 A national professional development program fills mentoring gaps for postdoctoral researchers

Sun, T.; Drane, D.; McGee, R.; Campa, H.; Goldberg, B. B.; Hokanson, S. C.

10.1101/2022.09.26.509546 — scientific communication and education — Posted on 2022-09-27

630 Substrate-binding Glycine Residues are Major Determinants for Hydrolase and Ligase Activity of Plant Legumains

Hemu, X.; Chan, N.-Y.; Liew, H. T.; Hu, S.; Zhang, X.; Serra, A.; Lescar, J.; Liu, C.-F.; Tam, J. P.

10.1101/2022.09.26.509423 — plant biology — Posted on 2022-09-27

631 Mapping of the bs5 and bs6 non-race-specific recessive resistances against bacterial spot of pepper

Sharma, A.; Li, J.; Wente, R.; Minsavage, G. V.; Gill, U. S.; Ortega, A.; Vallejos, C. E.; Hart, J. P.; Staskawicz, B. J.; Mazourek, M. R.; Stall, R. E.; Jones, J. B.; Hutton, S. F.

10.1101/2022.09.26.509408 — plant biology — Posted on 2022-09-27

632 Placental nanoparticle gene therapy normalizes gene expression changes in the fetal liver associated with fetal growth restriction in a fetal sex-specific manner

Wilson, R.; Stephens, K.; Jones, H.

10.1101/2022.09.26.509494 — physiology — Posted on 2022-09-27

633 Prorenin from renal tubules is a major driver of diabetic kidney disease

Federlein, A.; Lehrmann, C.; Tauber, P.; Todorov, V. T.; Schweda, F.

10.1101/2022.09.26.509473 — physiology — Posted on 2022-09-27

634 Quantitative proteomic analysis of skeletal muscles from wild type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies

Eckhardt, J.; Ruiz, A.; Koenig, S.; Frieden, M.; Schmidt, A.; Treves, S.; Zorzato, F.

10.1101/2022.09.26.509474 — physiology — Posted on 2022-09-27

635 Placental treatment with insulin-like growth factor 1 via nanoparticle differentially impacts vascular remodeling factors in guinea pig sub-placenta/decidua

Davenport, B.; Jones, H.; Wilson, R.

10.1101/2022.09.26.509492 — physiology — Posted on 2022-09-27

636 ROCKETS - a novel one-for-all toolbox for light sheet microscopy in drug discovery

Mueller, J. P.; Dobosz, M.; O'Brien, N.; Giusti, A. M.; Lechmann, M.; Osl, F.; Wolf, A.-K.; Sauer, M.; Herting, F.; Umana, P.; Poeschinger, T.; Beilhack, A.

10.1101/2022.09.26.509149 — pharmacology and toxicology — Posted on 2022-09-27

637 A natural history of networks: Higher-order network modeling for paleobiology research

Rojas, A.; Eriksson, A.; Neuman, M.; Edler, D.; Blocker, C.; Rosvall, M.

10.1101/2022.09.26.509538 — paleontology — Posted on 2022-09-27

638 Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS/AML

Wheeler, E. C.; Martin, B. J. E.; Doyle, W. C.; Gorelov, R. A.; Donahue, M.; Jann, J. C.; Abdel-Wahab, O.; Taylor, J.; Seiler, M.; Buonamici, S.; Belizaire, R.; Adelman, K.; Tothova, Z.

10.1101/2022.09.26.509430 — cancer biology — Posted on 2022-09-27

639 Updated site concordance factors minimize effects of homoplasy and taxon sampling

Mo, Y. K.; Lanfear, R.; Hahn, M. W.; Minh, B. Q.

10.1101/2022.09.26.509549 — bioinformatics — Posted on 2022-09-27

640 Identification of potential human pancreatic α-amylase inhibitors from natural products by molecular docking, MM/GBSA calculations, MD simulations, and ADMET analysis

Basnet, S.; Ghimire, M. P.; Lamichhane, T. R.; Adhikari, R.; Adhikari, A.

10.1101/2022.09.26.509544 — bioinformatics — Posted on 2022-09-27

641 Optical Biopsy using a neural network to predict functional state from photos of wounds

Teague, J.; Socia, D.; An, G.; Johnson, S.; Badylak, S.; Vodovotz, Y.; Jiang, P.; Cockrell, C.

10.1101/2022.09.26.509543 — bioinformatics — Posted on 2022-09-27

642 Engineering Alignment has Mixed Effects on hiPSC-CM Maturation

Kalkunte, N.; Delambre, T.; Sohn, S.; Pickett, M.; Parekh, S. H.; Zoldan, J.

10.1101/2022.09.26.509194 — bioengineering — Posted on 2022-09-27

643 3D Bioelectronics with a Remodellable Matrix for Long-term Tissue Integration and Recording

Boys, A. J.; Carnicer Lombarte, A.; Guemes Gonzalez, A.; van Niekerk, D. C.; Hilton, S.; Barone, D. G.; Proctor, C. M.; Owens, R. M.; Malliaras, G. G.

10.1101/2022.09.26.509464 — bioengineering — Posted on 2022-09-27

644 Residual Complex I activity supports glutamate catabolism and mtSLP via canonical Krebs cycle activity during acute anoxia without OXPHOS

Ravasz, D.; Bui, D.; Nazarian, S.; Pallag, G.; Karnok, N.; Roberts, J.; Tennant, D. A.; Greenwood, B.; Kitayev, A.; Hill, C.; Komlodi, T.; Doerrier, C.; Gnaiger, E.; Kiebish, M. A.; Raska, A.; Kolev, K.; Czumbel, B.; Narain, N. R.; Seyfried, T. N.; Chinopoulos, C.

10.1101/2022.09.26.509156 — biochemistry — Posted on 2022-09-27

645 Alendronate Conjugate for Targeted Delivery to Bone-Forming Prostate Cancer

Damasco, J.; Yu, G.; Kumar, A.; Lirag, R. C.; Whitley, E.; Lin, S.-H.; Melancon, M. P.

10.1101/2022.09.26.508175 — biochemistry — Posted on 2022-09-27

646 Ten new high-quality genome assemblies for diverse bioenergy sorghum genotypes

Voelker, W. G.; Krishnan, K.; Chougule, K.; Alexander, L. C.; Lu, Z.; Olson, A.; Ware, D.; Songsomboon, K.; Ponce, C. M.; Brenton, Z.; Boatwright, J. L.; Cooper, E. A.

10.1101/2022.09.26.509520 — genomics — Posted on 2022-09-27

647 Resolution of structural variation in diverse mouse genomes reveals chromatin remodeling due to transposable elements

Ferraj, A.; Audano, P. A.; Balachandran, P.; Czechanski, A.; Flores, J. I.; Radecki, A. A.; Mosur, V.; Gordon, D. S.; Walawalkar, I. A.; Eichler, E. E.; Reinholdt, L. G.; Beck, C. R.

10.1101/2022.09.26.509577 — genomics — Posted on 2022-09-27

648 Investigating community formation through dense spatial and temporal sampling of 5-6th century cemeteries in Pannonia

Vyas, D. N.; Koncz, I.; Modi, A.; Mende, B. G.; Tian, Y.; Francalacci, P.; Lari, M.; Vai, S.; Straub, P.; Gallina, Z.; Szeniczey, T.; Hajdu, T.; Radzeviciute, R.; Hofmanova, Z.; Evinger, S.; Bernert, Z.; Pohl, W.; Caramelli, D.; Vida, T.; Geary, P. J.; Veeramah, K. R.

10.1101/2022.09.26.509582 — genetics — Posted on 2022-09-27

649 Genetic Variation in Chromatin State Across Multiple Tissues in Drosophila melanogaster

Huynh, K.; Smith, B.; Macdonald, S.; Long, A.

10.1101/2022.09.26.509449 — genetics — Posted on 2022-09-27

650 Magnesium and the magnesium transporter UEX regulate sleep via Ca2+-dependent CREB signaling and a CNK-ERK pathway

Yuan, X.; Zheng, H.; Xu, X.; Deng, H.; Yang, X.; Xi, Y.

10.1101/2022.09.26.509486 — genetics — Posted on 2022-09-27

651 The enrichment of self-domestication and neural crest function loci in the heritability of neurodevelopmental disorders is not independent of genomic regulatory functions

Koller, D.; Benitez-Burraco, A.; Polimanti, R.

10.1101/2022.09.26.509526 — genetics — Posted on 2022-09-27

652 Population Structure and Migration in the Eastern Highlands of Papua New Guinea; a Region Impacted by the kuru Epidemic

Quinn, L.; Moltke, I.; Whitfield, J.; Alpers, M.; Campbell, T.; Hummerich, H.; Pomat, W.; Siba, P.; Koki, G.; Collinge, J.; Hellenthal, G.; Mead, S.

10.1101/2022.09.26.509478 — genetics — Posted on 2022-09-27

653 Historical Demography and Climate Driven Range Shifts in the Blue-spotted Salamander Under the Climate Change Scenarios

Perktas, U.; Elverici, C.; Yaylali, O.

10.1101/2022.09.26.509446 — evolutionary biology — Posted on 2022-09-27

654 Deleterious effects of thermal and water stresses on life history and physiology: a case study on woodlouse

DEPEUX, C.; BRANGER, A.; MOULIGNIER, T.; MOREAU, J.; Lemaitre, J.-F.; DECHAUME-MONCHARMONT, F.-X.; LAVERRE, T.; PAULHAC, H.; GAILLARD, J.-M.; BELTRAN-BECH, S.

10.1101/2022.09.26.509512 — evolutionary biology — Posted on 2022-09-27

655 Widespread sympatry in a species-rich clade of marine fishes (Carangoidei)

Glass, J. R.; Harrington, R. C.; Cowman, P. F.; Faircloth, B. C.; Near, T. J.

10.1101/2022.09.26.509594 — evolutionary biology — Posted on 2022-09-27

656 Numbers of mutations within multicellular bodies: why it matters

Frank, S. A.

10.1101/2022.09.26.509555 — evolutionary biology — Posted on 2022-09-27

657 Traditional phylogenetic models are insensitive to variations in the effective population size

Borges, R.; Kotari, I.; Bergman, J.; Chase, M.; Mugal, C. F.; Kosiol, C.

10.1101/2022.09.26.509598 — evolutionary biology — Posted on 2022-09-27

658 Evolutionary history of Euteliidae (Lepidoptera, Noctuoidea)

Zahiri, R.; Holloway, J. D.; Rota, J.; Schmidt, C.; Pellinen, M. J.; Kitching, I. J.; Miller, S. E.; Wahlberg, N.

10.1101/2022.09.26.508383 — evolutionary biology — Posted on 2022-09-27

659 Are Maximum Yields sustainable? Effect of intra-annualtime-scales on MSY, stability and resilience.

Ricouard, A.; Lehuta, S.; Mahevas, S.

10.1101/2022.09.26.509503 — ecology — Posted on 2022-09-27

660 Socioeconomics and biogeography jointly drive geographic biases in our knowledge of plant traits: a global assessment of the Raunkiaerian shortfall in plants

Maitner, B. S.; Gallagher, R.; Svenning, J.-C.; Tietje, M.; Wenk, E. H.; Eiserhardt, W. L.

10.1101/2022.09.26.509556 — ecology — Posted on 2022-09-27

661 Fitting individual-based models of species range dynamics to long-term monitoring data

Malchow, A.-K.; Fandos, G.; Kormann, U.; Grüebler, M.; Kery, M.; Hartig, F.; Zurell, D.

10.1101/2022.09.26.509574 — ecology — Posted on 2022-09-27

662 A conserved population of MHC II-restricted, innate-like, commensal-reactive T cells in the gut of humans and mice

Hackstein, C.-P.; Costigan, D.; Drexhage, L.; Pearson, C.; Bullers, S.; Ilott, N.; Akther, H. D.; Gu, Y.; FitzPatrick, M. E. B.; Harrison, O. J.; Garner, L. C.; Mann, E. H.; Pandey, S.; Friedrich, M.; Provine, N. M.; Uhlig, H.; Marchi, E.; Powrie, F.; Klenerman, P.; Thornton, E. E.

10.1101/2022.09.26.509581 — immunology — Posted on 2022-09-27

663 Chitinase-3-like 1 regulates TH2 cells, TFH cells and IgE following helminth infection

Curtiss, M. L.; Rosenberg, A. F.; Scharer, C. D.; Benavides, N. A. B.; Bradley, J. E.; Leon, B.; Steele, C. C.; Randall, T. D.; Lund, F. E.

10.1101/2022.09.26.507843 — immunology — Posted on 2022-09-27

664 Therapeutic potential of rWnt5A in curbing Leishmania donovani infection

Maity, S.; Sen, M.

10.1101/2022.09.26.509479 — immunology — Posted on 2022-09-27

665 Olfactory microvillar tuft cells direct neurogenesis during allergic inflammation

Ualiyeva, S.; Lemire, E. R.; Boyd, A.; Wong, C.; Aviles, E. C.; Maxfield, A.; Roditi, R.; Barett, N.; Barett, N.; Bucheit, K. M.; Laidlaw, T. M.; Boyce, J. A.; Bankova, L. G.; Haber, A. L.

10.1101/2022.09.26.509561 — immunology — Posted on 2022-09-27

666 A conserved role for stomatin domain genes in olfactory behavior

Liang, X.; Taylor, M.; Napier-Jameson, R.; Calovich-Benne, C.; Norris, A. D.

10.1101/2022.09.26.508537 — neuroscience — Posted on 2022-09-27

667 Personalized transcranial alternating current stimulation improves sleep quality: Initial Findings

Gurumoorthy, R.; Ayanampudi, V.; Kumar, V.; Krishnan, A.; Walker, M. P.; Ivry, R.; Knight, R. T.

10.1101/2022.09.26.509537 — neuroscience — Posted on 2022-09-27

668 Somatostatin slows Aβ plaque deposition in aged APPNL-F/NL-F mice by blocking Aβ aggregation in a neprilysin-independent manner

Williams, D.; Yan, B. Q.; Wang, H.; Negm, L.; Sackmann, C.; Verkuyl, C.; Rezai-Stevens, V.; Eid, S.; Sato, C.; Watts, J. C.; Wille, H.; Schmitt-Ulms, G.

10.1101/2022.09.26.509540 — neuroscience — Posted on 2022-09-27

669 Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories

Sias, A. C.; Jafar, Y.; Goodpaster, C. M.; Ramirez-Armenta, K.; Wrenn, T. M.; Griffin, N. K.; Sharpe, M. J.; Wassum, K. M.

10.1101/2022.09.26.509602 — neuroscience — Posted on 2022-09-27

670 A scalable implementation of the recursive least-squares algorithm for training spiking neural networks

Arthur, B. J.; Kim, C.; Chen, S.; Preibisch, S.; Darshan, R.

10.1101/2022.09.26.509578 — neuroscience — Posted on 2022-09-27

671 Conserved YKL-40 changes in mice and humans after postoperative delirium.

David-Bercholz, J.; Acker, L.; Caceres, A. I.; Wu, P. Y.; Goenka, S.; Franklin, N. O.; Rodriguiz, R. M.; Wetsel, W. C.; Devinney, M.; Wright, M. C.; Zetterberg, H.; Yang, T.; Berger, M.; Terrando, N.

10.1101/2022.09.26.509551 — neuroscience — Posted on 2022-09-27

672 A computational understanding of zoomorphic perception in the human brain

Duyck, S.; Bracci, S.; Op de Beeck, H.

10.1101/2022.09.26.509447 — neuroscience — Posted on 2022-09-27

673 Perturbation variance suppresses error sensitivity in the implicit learning system

Albert, S. T.; Shadmehr, R.

10.1101/2022.09.26.509572 — neuroscience — Posted on 2022-09-27

674 3D Printed Skull Cap and Benchtop Fabricated Microwire-based Microelectrode Array for Custom Rat Brain Recordings

Yi, D.; Hartner, J. P.; Ung, B. S.; Zhu, H. L.; Watson, B. O.; Chen, L.

10.1101/2022.09.26.509528 — neuroscience — Posted on 2022-09-27

675 Probing Action Potential Generation and Timing under Multiplexed Basal Dendritic Computations Using Two-photon 3D Holographic Uncaging

Xiao, S.; Yadav, S.; Jayant, K.

10.1101/2022.09.26.509562 — neuroscience — Posted on 2022-09-27

676 The Effect of P2X7 Antagonism on Subcortical Spread of Optogenetically-Triggered Cortical Spreading Depression and Neuroinflammation

Uzay, B.; Demir, B. D.; Ozcan, S. Y.; Kocak, E. E.; Yemisci, M.; Ozdemir, Y. G.; Dalkara, T.; Karatas, H.

10.1101/2022.09.26.509535 — neuroscience — Posted on 2022-09-27

677 Experience-dependent flexibility in a molecularly diverse central-to-peripheral auditory feedback system

Frank, M.; Sitko, A.; Suthakar, K.; Torres Cadenas, L.; Hunt, M.; Yuk, M. C.; Weisz, C.; Goodrich, L.

10.1101/2022.09.26.509230 — neuroscience — Posted on 2022-09-27

678 Biological age and brain age in midlife: relationship to multimorbidity and mental health

Zhang, F.; Chang, H.; Schaefer, S. M.; Gou, J.

10.1101/2022.09.26.509522 — neuroscience — Posted on 2022-09-27

679 Antiretroviral Therapy Does Not Restore Brain Lipids During SIV Infection: Regional Analysis of Metabolic Homeostasis and Depletion

White, C. J.; Gausepohl, A. M.; Seneviratne, H. K.; Bumpus, N. N.; Williams, D. W.

10.1101/2022.09.26.508302 — pathology — Posted on 2022-09-27

680 Inference of differential gene regulatory networks from gene expression data using boosted differential trees

Galindez, G. G.; List, M.; Baumbach, J.; Blumenthal, D. B.; Kacprowski, T.

10.1101/2022.09.26.509450 — bioinformatics — Posted on 2022-09-27

681 IBRAP: Integrated Benchmarking Single-cell RNA-sequencing Analytical Pipeline

Knight, C. H.; Khan, F.; Gill, U.; Wang, J.

10.1101/2022.09.26.509481 — bioinformatics — Posted on 2022-09-27

682 GutMeta: online microbiome analysis and interactive visualization with build-in curated human gut microbiome database

Jiang, Y.; Wang, Y.; Che, L.; Zhou, Q.; Li, S. C.

10.1101/2022.09.26.509484 — bioinformatics — Posted on 2022-09-27

683 DomainRank: Improving Biological Data Sets With Domain Knowledge and Google's PageRank

Schneider, M.; Rappsilber, J.; Brock, O.

10.1101/2022.09.26.509059 — bioinformatics — Posted on 2022-09-27

684 pCMLM: Genome Wide Association Study of Body Size Traits in Multiple Regions of Yak Based on the Provided Compressed Mixed Linear Model

Liu, X.; Chai, Z.; Peng, W.; Kangzhu, Y.; Zhong, J.; Wang, J.

10.1101/2022.09.26.509454 — bioinformatics — Posted on 2022-09-27

685 The Nematode Antimicrobial Peptidome: a novel opportunity for parasite control?

Irvine, A.; Huws, S. A.; Atkinson, L. E.; Mousley, A.

10.1101/2022.09.26.507570 — bioinformatics — Posted on 2022-09-27

686 Tumour growth: Bayesian parameter calibration of a multiphase porous media model based on in vitro observations of Neuroblastoma spheroid growth in a hydrogel microenvironment

Hervas-Raluy, S.; Wirthl, B.; Guerrero, P. E.; Robalo Rei, G.; Nitzler, J.; Coronado, E.; Font de Mora, J.; Schrefler, B. A.; Gomez-Benito, M. J.; Garcia-Aznar, J. M.; Wall, W. A.

10.1101/2022.09.26.509452 — bioengineering — Posted on 2022-09-27

687 The elasto-plastic nano- and microscale compressive behaviour of rehydrated mineralised collagen fibres

Groetsch, A.; Gourrier, A.; Casari, D.; Schwiedrzik, J.; Shephard, J. D.; Michler, J.; Zysset, P. K.; Wolfram, U.

10.1101/2022.09.26.509461 — bioengineering — Posted on 2022-09-27

688 External validation and further exploration of fall prediction models based on questionnaires and daily-life trunk accelerometry

Zhang, Y.; Weijer, R.; Schooten, K. v.; Bruijn, S. M.; Pijnappels, M.

10.1101/2022.09.26.509506 — bioengineering — Posted on 2022-09-27

689 Impact of non-proteinogenic amino acid norvaline and proteinogenic valine misincorporation on a secondary structure of a model peptide

Skibola, Z.; Gruic-Sovulj, I.; Marsavelski, A.

10.1101/2022.09.26.509456 — biochemistry — Posted on 2022-09-27

690 Structural foundations of potassium selectivity in channelrhodopsins

Govorunova, E. G.; Sineshchekov, O. A.; Brown, L.; Bondar, A.-N.; Spudich, J. L.

10.1101/2022.09.26.509509 — biochemistry — Posted on 2022-09-27

691 Programming super DNA-enzyme molecules for on-demand enzyme activity modulation

Zhao, H.; Xiu, X.; Li, M.; Gou, M.; Tao, L.; Zuo, X.; Fan, C.; Tian, Z.; Song, P.

10.1101/2022.09.26.509444 — biochemistry — Posted on 2022-09-27

692 Extracting extended vocal units from two neighborhoods in the embedding plane

Lorenz, C.; Hao, X.; Tomka, T.; Ruettimann, L.; Hahnloser, R.

10.1101/2022.09.26.509501 — animal behavior and cognition — Posted on 2022-09-27

693 Quartet RNA reference materials and ratio-based reference datasets for reliable transcriptomic profiling

Yu, Y.; Hou, W.; Wang, H.; Dong, L.; Liu, Y.; Sun, S.; Yang, J.; Cao, Z.; Zhang, P.; Zi, Y.; Li, Z.; Liu, R.; Gao, J.; Chen, Q.; Zhang, N.; Li, J.; Ren, L.; Jiang, H.; Shang, J.; Zhu, S.; Wang, X.; Qing, T.; Bao, D.; Li, B.; Li, B.; Suo, C.; Pi, Y.; Wang, X.; Dai, F.; Scherer, A.; Mattila, P.; Han, J.; Zhang, L.; Jiang, H.; Thierry-Mieg, D.; Thierry-Mieg, J.; Xiao, W.; Hong, H.; Tong, W.; Wang, J.; Li, J.; Fang, X.; Jin, L.; Shi, L.; Xu, J.; Qian, F.; Zhang, R.; Zheng, Y.

10.1101/2022.09.26.507265 — genetics — Posted on 2022-09-27

694 An ABM of biting midge dynamics to understand Bluetongue outbreaks

Gladson, S. L.; Stepien, T. L.

10.1101/2022.09.26.509502 — ecology — Posted on 2022-09-27

695 IL-12-expressing highly immunogenic recombinant modified vaccinia virus Ankara reprograms tumor-infiltrating myeloid cells to overcome immune resistance

Liu, S.; Mazo, G.; Yang, N.; Zhang, T.; Wang, Y.; Baseer Tariq, S.; Wang, Y.; Hirschhorn-Cymerman, D.; Ji, L.; Tan, A.; Wang, J.; Yan, W.; Choi, J.; Xiang, J. Z.; Li, M. O.; Merghoub, T.; Wolchok, J. D.; Deng, L.

10.1101/2022.09.25.509429 — immunology — Posted on 2022-09-27

696 Biochemical and metabolic maladaption defines pathological niches in progressive multiple sclerosis

Grant-Peters, M.; Rich-Griffin, C.; Yeung, H.-Y.; Thomas, T.; Davis, S.; Azizian, M.; Fisher, J.; Fischer, R.; Cinque, G. A.; Dendrou, C. A.

10.1101/2022.09.26.509462 — neuroscience — Posted on 2022-09-27

697 Increase the flow rate and improve hydrogen deuterium exchange mass spectrometry

Peterle, D.; DePice, D.; Wales, T. E.; Engen, J. R.

10.1101/2022.09.25.509411 — biophysics — Posted on 2022-09-27

698 Spurious off-target signals from potential lncRNAs by 10X Visium probes

Prakrithi, P.; Sami, J.; Jain, D.; Malik, P. S.; Gupta, I.

10.1101/2022.09.25.509336 — bioinformatics — Posted on 2022-09-27

699 The genetic basis for adaptation in giant sea anemones to their symbiosis with anemonefish and Symbiodiniaceae

Barua, A.; Kashimoto, R.; Khalturin, K.; Satoh, N.; Laudet, V.

10.1101/2022.09.25.509434 — evolutionary biology — Posted on 2022-09-27

700 Coevolutionary maintenance of forked tails and song in hirundines (Aves: Hirundininae)

Hasegawa, M.

10.1101/2022.09.25.509392 — evolutionary biology — Posted on 2022-09-27

701 Associations of maternal prenatal emotional symptoms and cortisol with neonatal meconium microbiota: A cross-sectional study

Deflorin, N.; Ehlert, U.; Amiel Castro, R.

10.1101/2022.09.25.509368 — microbiology — Posted on 2022-09-27

702 Phase of firing does not reflect temporal order in sequence memory of humans and recurrent neural networks

Liebe, S.; Niediek, J.; Pals, M.; Reber, T. P.; Faber, J.; Bostroem, J.; Elger, C. E.; Macke, J. H.; Mormann, F.

10.1101/2022.09.25.509370 — neuroscience — Posted on 2022-09-27

703 Amyloid-beta biomarkers in Braak stages and their predictive relationships with cognitive impairment: Support vector machine and deep learning approaches

Taha, A.; Soni, B.; Thakuri, D. S.; Ritter, E.; Bhattarai, P.; Chand, G.

10.1101/2022.09.25.509432 — neuroscience — Posted on 2022-09-27

704 Brain mechanism of foraging: reward-dependentsynaptic plasticity or neural integration of values?

Pereira-Obilinovic, U.; Hou, H.; Svoboda, K.; Wang, X.-J.

10.1101/2022.09.25.509030 — neuroscience — Posted on 2022-09-27

705 Adaptive mechanisms facilitate robust performance in noise and in reverberation in an auditory categorization model

Parida, S.; Liu, S. T.; Sadagopan, S.

10.1101/2022.09.25.509412 — neuroscience — Posted on 2022-09-27

706 Effects of Simvastatin on RBL-2H3 cell degranulation.

Yoshii, M.; Kitazaki, A.; Ozawa, K.

10.1101/2022.09.25.509437 — pharmacology and toxicology — Posted on 2022-09-27

707 Gene panel design for spatial transcriptomics with prioritized gene sets

Yafi, M. A.; Hisham, M. H. H.; Grisanti, F.; Rahman, A.; Samee, M. A. H.

10.1101/2022.09.25.509418 — bioinformatics — Posted on 2022-09-27

708 de novo diploid genome assembly using long noisy reads via haplotype-aware error correction and inconsistent overlap identification

Nie, F.; Huang, N.; Zhang, J.; Ni, P.; Wang, Z.; Xiao, C.-L.; Luo, F.; Wang, J.

10.1101/2022.09.25.509436 — bioinformatics — Posted on 2022-09-27

709 SmartGate is a spatial metabolomics tool for resolving tissue structures

Xiao, K.; Wang, Y.; Dong, K.; Zhang, S.

10.1101/2022.09.25.509375 — bioinformatics — Posted on 2022-09-27

710 clrDV: A differential variability test for RNA-Seqdata based on the skew-normal distribution

Khang, T. F.; Li, H.

10.1101/2022.09.25.508885 — bioinformatics — Posted on 2022-09-27

711 A Visual, Inexpensive, and Wireless Capillary Rheometer

Du, J.; Sinha, S.; Lee, S.; Skylar-Scott, M.

10.1101/2022.09.25.509390 — bioengineering — Posted on 2022-09-27

712 The Micromechanical Environment of the Impinged Achilles Tendon Insertion

Mora, K. E.; Mlawer, S. J.; Loiselle, A. E.; Buckley, M. R.

10.1101/2022.09.25.509413 — bioengineering — Posted on 2022-09-27

713 A non-ligand surrogate agonist antibody that enhances canonical Wnt signaling and bone regeneration

Lee, N.-K.; Bidlingmaier, S.; Su, Y.; Seo, Y.; Liu, B.

10.1101/2022.09.25.509440 — bioengineering — Posted on 2022-09-27

714 Recombination rate variation shapes genomic variability of phylogeographic structure in a widespread North American songbird (Aves: Certhia americana)

Manthey, J. D.; Spellman, G. M.

10.1101/2022.09.25.509431 — evolutionary biology — Posted on 2022-09-27

715 CorA gene rearrangement triggered the salinity-driven speciation of Poseidoniales

Fan, L.; Xu, B.; Chen, S.; Liu, Y.; Li, F.; Xie, W.; Prabhu, A.; Zou, D.; Wan, R.; Li, H.; Liu, H.; Liu, Y.; Kao, S.-J.; Chen, J.; Zhu, Y.; Rinke, C.; Li, M.; Zhang, C.

10.1101/2022.09.25.509439 — evolutionary biology — Posted on 2022-09-27

716 An Improved Algorithm for Inferring Mutational Parameters from Bar-Seq Evolution Experiments

Li, F.; Mahadevan, A.; Sherlock, G.

10.1101/2022.09.25.509409 — evolutionary biology — Posted on 2022-09-27

717 Gut bacteria-derived serotonin promotes immune tolerance in early life

Sanidad, K. Z.; Rager, S. L.; Ananthanarayanan, A.; Callaghan, R.; Li, T.; Brown, J. A.; Amir, M.; Jin, J. L.; Savage, A. R.; Luo, R.; Mardorsky Rowdo, F.; Martin, M. L.; Silver, R. B.; Artis, D.; Guo, C.-J.; Krumsiek, J.; Inohara, N.; Zeng, M. Y.

10.1101/2022.09.25.509428 — immunology — Posted on 2022-09-27

718 Impact of cellular prion protein expression on disease progression and pathology in two mouse models of Alzheimer's disease

Purro, S. A.; Farmer, M.; Noble, E.; Sarell, C. J.; Powell, M.; Yip, D. C.-M.; Giggins, L.; Zakka, L.; Thomas, D. X.; Farrow, M. A.; Nicoll, A. J.; Walsh, D. M.; Collinge, J.

10.1101/2022.09.25.508690 — neuroscience — Posted on 2022-09-27

719 Inferential Eye Movement Control while Following Dynamic Gaze

Han, N. X.; Eckstein, M. P.

10.1101/2022.09.25.508620 — neuroscience — Posted on 2022-09-27

720 From Correlation to Communication: disentangling hidden factors from functional connectivity changes

Yu, Y.; Gratton, C.; Smith, D. M.

10.1101/2022.09.25.509384 — neuroscience — Posted on 2022-09-27

721 Computing Minimal Boolean Models of Gene Regulatory Networks

Karlebach, G.; Robinson, P. N.

10.1101/2021.05.22.445266 — systems biology — Posted on 2022-09-27

722 Identifying Genes with Location Dependent Noise Variance in Spatial Transcriptomics Data

Abrar, M. A.; Kaykobad, M.; Rahman, M. S.; Samee, M. A. H.

10.1101/2022.09.25.509381 — systems biology — Posted on 2022-09-27

723 Assessing single-component gene drive systems in the mosquito Aedes aegypti via single generation crosses and modeling

Reid, W. R.; Lin, J.; Williams, A. E.; Juncu, R.; Olson, K. E.; Franz, A. W. E.

10.1101/2021.12.08.471839 — synthetic biology — Posted on 2022-09-27

724 A Complete Set of Equations for a Computational Model of Electrolyte and Water Transport along the Nephrons in a Mammalian Kidney

Layton, A.

10.1101/2022.09.23.509286 — physiology — Posted on 2022-09-27

725 Taxon cycles in Neotropical mangroves

Rull, V.

10.1101/2022.09.25.509361 — paleontology — Posted on 2022-09-27

726 IMPatienT: an Integrated web application to digitize, process and explore Multimodal PATIENt daTa.

Meyer, C.; Romero, N.; Evangelista, T.; Cadot, B.; Laporte, J.; Jeannin-Girardon, A.; Collet, P.; Chennen, K.; Poch, O.

10.1101/2022.04.08.487635 — bioinformatics — Posted on 2022-09-27

727 Generating an in vitro gut model with physiologically relevant biophysical mucus properties

McCright, J. C.; Sinha, A.; Maisel, K.

10.1101/2022.02.18.481062 — bioengineering — Posted on 2022-09-27

728 Operational Gene Clusters and intrinsic uncertainty in pangenome analyses

Manzano-Morales, S.; Liu, Y.; Huerta-Cepas, J.; Iranzo, J.

10.1101/2022.09.25.509376 — genomics — Posted on 2022-09-27

729 Rapid reductions in population size drive evolutionary divergence in diatoms

Walworth, N. G.; Espinoza, J. L.; Argyle, P. A.; Hinners, J.; Levine, N. M.; Doblin, M. A.; Dupont, C. L.; Collins, S.

10.1101/2022.09.25.509407 — evolutionary biology — Posted on 2022-09-27

730 Quantifying Spatio-Temporal Overlap of Invasive Wild Pigs and Domestic Pig Farms as a Proxy for Potential Disease Transmission Risk

Brook, R. K.; Aschim, R.

10.1101/2022.09.25.509397 — ecology — Posted on 2022-09-27

731 A silent disco: Persistent entrainment of low-frequency neural oscillations underlies beat-based, but not pattern-based temporal expectations

Bouwer, F. L.; Fahrenfort, J. J.; Millard, S. K.; Kloosterman, N. A.; Slagter, H. A.

10.1101/2020.01.08.899278 — neuroscience — Posted on 2022-09-27

732 Heterogeneity of burst firing in mouse thalamic reticular nucleus neurons

Harding-Jackson, L.; Beatty, J. A.; Cox, C. L.

10.1101/2022.09.25.509400 — neuroscience — Posted on 2022-09-27

733 Feasibility Analyses and Experimental Confirmation of Dove Prism Based Dual-fiberscope Rotary Joint

Liu, Y.; Park, H.-C.; Zhang, H.; Li, X.

10.1101/2022.09.25.509388 — neuroscience — Posted on 2022-09-27

734 Thalamic volume and functional connectivity are associated with nicotine dependence severity and craving

Lor, C. S.; Haugg, A.; Zhang, M.; Schneider, L.; Herdener, M.; Quednow, B. B.; Golestani, N.; Scharnowski, F.

10.1101/2022.09.25.509385 — neuroscience — Posted on 2022-09-27

735 "Primed to Perform:" Dynamic white matter graph communicability may drive metastable network representations of enhanced preparatory cognitive control

Buch, V. P.; Bernabei, J. M.; Ng, G. Y.; Richardson, A. G.; Ramayya, A.; Brandon, C.; Stiso, J.; Bassett, D. S.; Lucas, T. H.

10.1101/2022.09.25.509351 — neuroscience — Posted on 2022-09-27

736 Investigation of Molecular Weights and Pharmacokinetic Characteristics of Older and Modern Small Drugs

Fagerholm, U.

10.1101/2022.09.21.508888 — pharmacology and toxicology — Posted on 2022-09-27

737 Population Genomics of Stone Age Eurasia

Allentoft, M. E.; Sikora, M.; Refoyo-Martinez, A.; Irving-Pease, E. K.; Fischer, A.; Barrie, W.; Ingason, A.; Stenderup, J.; Sjögren, K.-G.; Pearson, A.; Sousa da Mota, B.; Paulsson, B. S.; Halgren, A. S.; Macleod, R.; Schjellerup Jorkov, M. L.; Demeter, F.; Novosolov, M.; Sorensen, L.; Nielsen, P. O.; Henriksen, R. A.; Vimala, T.; McColl, H.; Margaryan, A.; Ilardo, M.; Vaughn, A.; Mortensen, M. F.; Nielsen, A. B.; Hede, M. U.; Rasmussen, P.; Vinner, L.; Renaud, G.; Stern, A. J.; Trolle Jensen, T. Z.; Johannsen, N. N.; Scorrano, G.; Schroeder, H.; Lysdahl, P.; Ramsoe, A.; Skorobogatov, A.; Sc

10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2022-09-27

738 Tensor Decomposition Discriminates Tissues Using scATAC-seq

Taguchi, Y.-h.; Turki, T.

10.1101/2022.08.04.502875 — bioinformatics — Posted on 2022-09-27

739 Evolution of immune genes in island birds: reduction in population sizes can explain island syndrome

Barthe, M.; Doutrelant, C.; Covas, R.; Melo, M.; Illera, J. C.; Tilak, M.-K.; Colombier, C.; Leroy, T.; Loiseau, C.; Nabholz, B.

10.1101/2021.11.21.469450 — evolutionary biology — Posted on 2022-09-27

740 Novel phosphorylation of Rab29 that regulates its localization and lysosomal stress response in concert with LRRK2

Komori, T.; Kuwahara, T.; Fujimoto, T.; Sakurai, M.; Iwatsubo, T.

10.1101/2022.09.26.509472 — molecular biology — Posted on 2022-09-27

741 An analytical model describing the mechanics of erythrocyte membrane wrapping during active invasion of a plasmodium falciparum merozoite

Msosa, C.; Abdalrahman, T.; Franz, T.

10.1101/2022.06.14.496094 — biophysics — Posted on 2022-09-27

742 Nicotinamide-N-methyltransferase is essential for SAM and 1-methylnicotinamide homeostasis in the AML12 hepatocyte cell line

Yoda, M.; Mizuno, R.; Yoshihiro, I.; Takahashi, M.; Bamba, T.; Kawaoka, S.

10.1101/2022.09.25.509348 — biochemistry — Posted on 2022-09-27

743 HSP70-binding motifs function as protein quality control degrons

Abildgaard, A. B.; Voutsinos, V.; Petersen, S. D.; Larsen, F. B.; Kampmeyer, C.; Johansson, K. E.; Stein, A.; Ravid, T.; Andreasson, C.; Jensen, M. K.; Lindorff-Larsen, K.; Hartmann-Petersen, R.

10.1101/2021.12.22.473789 — biochemistry — Posted on 2022-09-27

744 Human cellular homeostasis buffers trans-acting translational effects of heterologous gene expression with very different codon usage bias

JALLET, A. J.; Demange, A.; Leblay, F.; Decourcelle, M.; El Koulali, K.; Picard, M. A.; Bravo, I. G.

10.1101/2021.12.09.471957 — cell biology — Posted on 2022-09-27

745 Gliding towards an understanding of the origin of flight in bats

Burtner, A. E.; Grossnickle, D. M.; Santana, S. E.; Law, C. J.

10.1101/2022.09.26.509622 — evolutionary biology — Posted on 2022-09-27

746 Clonally related, Notch-differentiated spinal neurons integrate into distinct circuits

Bello-Rojas, S.; Bagnall, M. W.

10.1101/2022.09.26.509532 — neuroscience — Posted on 2022-09-27

747 Mitf is a Schwann Cell Sensor of Axonal Integrity that Drives Nerve Repair

Daboussi, L.; Costaguta, G.; Gullo, M.; Pessino, V.; O'Leary, B.; Lettieri, K.; Driscoll, S.; Pfaff, S. L.

10.1101/2022.09.25.509350 — neuroscience — Posted on 2022-09-27

748 Human-like Modulation SensitivityEmerging through Optimization to Natural Sound Recognition

Koumura, T.; Terashima, H.; Furukawa, S.

10.1101/2022.09.25.509427 — neuroscience — Posted on 2022-09-27

749 Hippocampo-cortical circuits for selective memory encoding, routing, and replay

Harvey, R. E.; Robinson, H. L.; Liu, C.; Oliva, A.; Fernandez-Ruiz, A.

10.1101/2022.09.25.509420 — neuroscience — Posted on 2022-09-27

750 Students Attitudes Surrounding STEM: A Social Cognitive Career Theory Instrument for High School

McDonough, E.; Sawyer, K. S.; Wilks, J.; Jacque, B.

10.1101/2021.11.29.470294 — scientific communication and education — Posted on 2022-09-27

751 Positive, negative and engineered durotaxis

Saez, P.; Venturini, C.

10.1101/2022.09.26.508682 — biophysics — Posted on 2022-09-26

752 Hydrostatic pressure and lateral actomyosin tension control stretch and tension of the basement membrane in epithelia

Guerra Santillan, K. Y.; Dahmann, C.; Fischer-Friedrich, E.

10.1101/2022.09.02.506324 — biophysics — Posted on 2022-09-27

753 Seasonality of host-seeking Ixodes ricinus nymph abundance in relation to climate

Hoch, T.; Madouasse, A.; Jacquot, M.; Wongnak, P.; Beugnet, F.; Bournez, L.; Huard, F.; Moutailler, S.; Plantard, O.; Poux, V.; Rene-Martellet, M.; Vayssier-Taussat, M.; Verheyden, H.; Vourc'h, G.; Chalvet-Monfray, K.; Agoulon, A.

10.1101/2022.07.25.501416 — ecology — Posted on 2022-09-27

754 Antagonistic H3K79me-H3K9ac crosstalk determines elongation at housekeeping genes to promote pluripotency

Wille, C. K.; Zhang, X.; Haws, S.; Denu, J.; Sridharan, R.

10.1101/2022.09.26.509534 — developmental biology — Posted on 2022-09-27

755 3D Ground Truth Annotations of Nuclei in 3D Microscopy Volumes

Chen, A.; Wu, L.; Winfree, S.; Dunn, K. W.; Salama, P.; Delp, E. J.

10.1101/2022.09.26.509542 — cell biology — Posted on 2022-09-26

756 ATR protects centromere identity by promoting DAXX association with PML nuclear bodies

Trier, I.; Joo, Y. K.; Black, E.; Kabeche, L.

10.1101/2022.09.26.509554 — cell biology — Posted on 2022-09-26

757 Single-molecule imaging of cytoplasmic dynein in cellulo reveals the mechanism of motor activation and cargo movement

Tirumala, N. A.; Redpath, G. M. I.; Kapoor-Kaushik, N.; Ariotti, N.; Dolai, P.; Kumar, K. V.; Ananthanarayanan, V.

10.1101/2021.04.05.438428 — cell biology — Posted on 2022-09-27

758 Septins regulate border cell shape and surface geometry downstream of Rho

Gabbert, A. M.; Mondo, J.; Campanale, J. P.; Mitchell, N. P.; Myers, A.; Streichan, S. J.; Miolane, N.; Montell, D. J.

10.1101/2021.04.08.439079 — cell biology — Posted on 2022-09-27

759 Modulatory mechanisms of TARP γ8-selective AMPA receptor therapeutics

Zhang, D.; Lape, R.; Shaikh, S. A.; Kohegyi, B. K.; Watson, J. F.; Cais, O.; Nakagawa, T.; Greger, I. H.

10.1101/2022.09.25.509219 — neuroscience — Posted on 2022-09-26

760 Neuronal activity-related transcription is blunted in immature compared to mature dentate granule cells

Parylak, S. L.; Qiu, F.; Linker, S. B.; Gallina, I. S.; Lim, C. K.; Preciado, D.; McDonald, A. H.; Gage, F. H.

10.1101/2022.09.26.508896 — neuroscience — Posted on 2022-09-26

761 Ultrastructure of synaptic connectivity within sub-regions of the SCN revealed by genetically encoded EM tag and SBEM

Calligaro, H.; Shoghi, A.; Chen, X.; Kim, K.-Y.; Liu, Y. H.; Khov, B.; Finander, B.; Le, H.; Ellisman, M. H.; Panda, S.

10.1101/2022.09.26.509467 — neuroscience — Posted on 2022-09-26

762 A positively tuned voltage indicator reveals electrical correlates of calcium activity in the brain

Evans, S. W.; Shi, D.; Chavarha, M.; Plitt, M. H.; Taxidis, J.; Madruga, B.; Fan, J. L.; Hwang, F.-J.; Van Keulen, S. C.; Suomivuori, C.-M.; Pang, M.; Su, S.; Zhang, G.; Lee, S.; Jiang, D.; Pradhan, L.; Liu, Y.; Reese, A.; Negrean, A.; Losonczy, A.; Makinson, C. D.; Wang, S.; Clandinin, T.; Dror, R.; Ding, J. B.; Ji, N.; Golshani, P.; Giocomo, L. M.; Bi, G. G.; Lin, M. Z.

10.1101/2021.10.21.465345 — neuroscience — Posted on 2022-09-27

763 SCF-FBXW7 regulates G2-M progression through control of CCNL1 ubiquitination

O'Brien, S.; Kelso, S.; Steinhart, Z.; Orlicky, S.; Mis, M.; Kim, Y.; Lin, S.; Sicheri, F.; Angers, S.

10.1101/2022.09.26.509608 — cancer biology — Posted on 2022-09-26

764 Circadian rhythm orthologs drive pulses of heterochronic miRNA transcription in C. elegans

Kinney, B.; Sahu, S.; Stec, N.; Hills-Muckey, K.; Adams, D.; Wang, J.; Jaremako, M.; Joshua-Tor, L.; Keil, W.; Hammell, C. M.

10.1101/2022.09.26.509508 — developmental biology — Posted on 2022-09-26

765 A tissue-specific ubiquitin switch coordinates brain, craniofacial, and skin development

Asmar, A. J.; Yazejian, R. M.; Wu, Y.; Collins, J. C.; Hsin, J.; Cho, J.; Doyle, A. D.; Cinthala, S.; Simon, M.; van Jaarsveld, R. H.; Beck, D. B.; Kerosuo, L.; Werner, A.

10.1101/2022.09.26.509591 — developmental biology — Posted on 2022-09-26

766 Transposase N-terminal phosphorylation and asymmetric transposon ends inhibit piggyBac transposition in mammalian cells

Luo, W.; Hickman, A.; Genzor, P.; Ghirlando, R.; Furman, C. M.; Menshikh, A.; Haase, A. D.; Dyda, F.; Wilson, M. H.

10.1101/2022.09.26.509586 — molecular biology — Posted on 2022-09-26

767 Pharmacologic Stabilization of Retromer Rescues Endosomal Pathology Induced by Defects in the Alzheimer's gene SORL1

Mishra, S.; Knupp, A.; Kinoshita, C.; Martinez, R.; Theofilas, P.; Young, J. E.

10.1101/2022.07.31.502217 — neuroscience — Posted on 2022-09-26

768 Moving Beyond Processing and Analysis-Related Variation in Neuroscience

Li, X.; Ai, L.; Giavasis, S.; Jin, H.; Feczko, E.; Xu, T.; Clucas, J.; Franco, A.; Heinsfeld, A. S.; Adebimpe, A.; Vogelstein, J. T.; Yan, C.-G.; Esteban, O.; Poldrack, R. A.; Craddock, C.; Fair, D.; Satterthwaite, T.; Kiar, G.; Milham, M. P.

10.1101/2021.12.01.470790 — neuroscience — Posted on 2022-09-26

769 Kidney collecting duct cells make vasopressin in response to NaCl induced hypertonicity

Arroyo, J. P.; Terker, A. S.; Zuchowski, Y.; Watts, J. A.; Bock, F.; Meyer, C.; Luo, W.; Kapp, M. E.; Gould, E. R.; Jiang, M.; Miranda, A. X.; Jiang, M.; Vanacore, R.; Hammock, E.; Wilson, M.; Zent, R.; Zhang, M.-Z.; Bhave, G.; Harris, R. C.

10.1101/2022.05.13.491898 — physiology — Posted on 2022-09-26

770 Improving peptide-level mass spectrometry analysis via double competition

Lin, A.; Short, T.; Noble, W. S.; Keich, U.

10.1101/2022.05.11.491571 — bioinformatics — Posted on 2022-09-26

771 Reprogramming Adeno-Associated Virus Tropism Via Displayed Peptides Tiling Receptor-Ligands

Portell, A.; Ford, K. M.; Suhardjo, A.; Rainaldi, J.; Bublik, M. N.; Sanghvi, M.; Kumar, A.; Wing, M. K.; Palmer, N. D.; Le, D. A.; Kalahasti, N.; Dailamy, A.; Mali, P.

10.1101/2022.09.26.509383 — bioengineering — Posted on 2022-09-26

772 Biomimetic S-adenosylmethionine regeneration for nucleophilic and radical alkylation reactions and aminopropyltransfer

Gericke, L.; Karst, L. C.; Mhaindarkar, D.; Jahn, S.; Kuge, M.; Mohr, M. K. F.; Gagsteiger, J.; Cornelissen, N. V.; Wen, X.; Mordhorst, S.; Jessen, H.; Rentmeister, A.; Seebeck, F. P.; Layer, G.; Loenarz, C.; Andexer, J. N.

10.1101/2022.09.26.509380 — biochemistry — Posted on 2022-09-26

773 Complex scaffold remodeling in plant triterpene biosynthesis

De La Pena, R.; Hodgson, H.; Liu, J. C. T.; Stephenson, M. J.; Martin, A. C.; Owen, C.; Harkess, A.; Leebens-Mack, J.; Jimenez, L. E.; Osbourn, A.; Sattely, E. S.

10.1101/2022.09.26.509531 — biochemistry — Posted on 2022-09-26

774 An Aurora B-RPA signaling axis secures chromosome segregation fidelity

Roshan, P.; Kuppa, S.; Mattice, J.; Kaushik, V.; Chadda, R.; Pokhrel, N.; Tumala, B.; Bothner, B.; Antony, E.; Origanti, S.

10.1101/2022.09.26.509563 — biochemistry — Posted on 2022-09-26

775 Transcriptome landscape of kleptoplastic sea slug Elysia viridis

Mendoza, M.; Rocha, S.; Troncoso, J.; Posada, D.; Canchaya, C. A.

10.1101/2022.06.28.497858 — evolutionary biology — Posted on 2022-09-26

776 The Role of EBP50 in Regulating Endothelial-To-Mesenchymal Transition in Pulmonary Hypertension

Gorelova, A.; Berman, M.; Sharifi-Sanjani, M.; Pulgarin Rocha, A.; Alsuraimi, A.; Riva, P.; Negi, V.; Bertero, T.; Goncharov, D.; Kudryashova, T.; Dosunmu-Ogunbi, A.; Rajaratnam, A.; Harvey, L.; Nouraie, M.; Baust, J.; Bachman, T.; Sembrat, J.; Vargas, S. O.; Waxman, A. B.; Saggar, R.; Kumar, R.; Graham, B.; Straub, A. C.; Goncharova, E. A.; Mora, A.; Chan, S. Y.; Al Ghouleh, I.

10.1101/2022.05.31.494181 — cell biology — Posted on 2022-09-26

777 Novel phosphorylation of Rab29 that regulates its localization and lysosomal stress response in concert with LRRK2

Komori, T.; Kuwahara, T.; Fujimoto, T.; Sakurai, M.; Iwatsubo, T.

10.1101/2022.09.26.509472 — molecular biology — Posted on 2022-09-26

778 AF2-multimer guided high accuracy prediction of typical and atypical ATG8 binding motifs

Ibrahim, T.; Khandare, V.; Mirkin, F. G.; Tumtas, Y.; Bubeck, D.; Bozkurt, T. O.

10.1101/2022.09.25.509395 — molecular biology — Posted on 2022-09-26

779 CRISPR/Cas9 mediated gene editing in non-model nematode Panagrolaimus sp. PS1159

Hellekes, V.; Claus, D.; Seiler, J.; Illner, F.; Schiffer, P.; Kroiher, M.

10.1101/2022.09.26.509268 — molecular biology — Posted on 2022-09-26

780 In vitro synergistic action of TAT-RasGAP317-326 peptide with antibiotics against Gram-negative pathogens

Vizzarro, G.; Jacquier, N.

10.1101/2022.09.26.509445 — microbiology — Posted on 2022-09-26

781 Sinking diatom aggregates provide carbon to drive microscale denitrification in a bulk oxygenated ocean

Ciccarese, D.; Tantawi, O.; Zhang, I.; Plata, D.; Babbin, A. R.

10.1101/2022.09.26.509232 — microbiology — Posted on 2022-09-26

782 Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

Olaitan, A. O.; Dureja, C.; Youngblom, M.; Topf, M. A.; Shen, W.-J.; Gonzales-Luna, A. J.; Deshpande, A.; Hevener, K. E.; Freeman, J.; Wilcox, M. H.; Palmer, K. L.; Garey, K. W.; Pepperell, C. S.; Hurdle, J. G.

10.1101/2022.09.23.509282 — microbiology — Posted on 2022-09-26

783 Bordetella Spp. Utilize T3SS To Promote Secretion of IL1RA Leading to Long-Term Per-sistent Infections

Williams, T. L.; Roan, C.; First, N. J.; Johnson, S.; Gestal, M. C.

10.1101/2022.09.26.509564 — microbiology — Posted on 2022-09-26

784 Group B Streptococcus Adaptation Promotes Survival in a Hyper-inflammatory Diabetic Wound Environment

Keogh, R. A.; Haeberle, A. L.; Langouët-Astrie, C. J.; Kavanaugh, J. S.; Schmidt, E. P.; Moore, G. D.; Horswill, A. R.; Doran, K. S.

10.1101/2022.06.27.497804 — microbiology — Posted on 2022-09-26

785 The genetic architecture of adaptation to leaf and root bacterial microbiota in Arabidopsis thaliana

Roux, F.; Frachon, L.; Bartoli, C.

10.1101/2022.09.26.509609 — microbiology — Posted on 2022-09-26

786 Queuosine modification of tRNA-Tyrosine elicits translational reprogramming and enhances growth of Vibrio cholerae with aminoglycosides.

Fruchard, L.; Babosan, A.; Carvalho, A.; Lang, M.; Li, B.; Duchateau, M.; Giai Gianetto, Q.; Matondo, M.; Bonhomme, F.; Fabret, C.; NAMY, O.; de Crecy-Lagard, V.; Mazel, D.; Baharoglu, Z.

10.1101/2022.09.26.509455 — microbiology — Posted on 2022-09-26

787 Shared and unique responses in the microbiome of allopatric lizards reared in a standardized environment

Assis, B. A.; Bell, T.; Engler, H. I.; King, W. L.

10.1101/2022.09.26.509558 — microbiology — Posted on 2022-09-26

788 Cluster-driven evolution and modularity uncover paths of cholera emergence

Lopez-Perez, M.; Grant, T.-A.; Haro-Moreno, J. M.; Zaragoza-Solas, A.; Almagro-Moreno, S.

10.1101/2022.09.26.509565 — microbiology — Posted on 2022-09-26

789 Prioritized single-cell proteomics reveals molecular and functional polarization across primary macrophages

Huffman, R. G.; Leduc, A.; Wichmann, C.; di Gioia, M.; Borriello, F.; Specht, H.; Derks, J.; Khan, S.; Khoury, L.; Emmott, E.; Petelski, A. A.; Perlman, D. H.; Cox, J.; Zanoni, I.; Slavov, N.

10.1101/2022.03.16.484655 — immunology — Posted on 2022-09-26

790 A repertoire of foraging decision variables in the mouse brain

Cazettes, F.; Mazzucato, L.; Murakami, M.; Morais, J. P.; Renart, A.; Mainen, Z.

10.1101/2021.04.01.438090 — neuroscience — Posted on 2022-09-26

791 EMC10 reduction in human neurons and adult mouse brain rescues cellular and behavioral deficits linked to 22q11.2 deletion

Thakur, P.; Lackinger, M.; Diamantopoulou, A.; Rao, S.; Chen, Y.; Ferng, A.; Mazur, C.; Kordasiewicz, H.; Shprintzen, R. J.; Markx, S.; Xu, B.; Gogos, J. A.

10.1101/2022.03.01.482495 — neuroscience — Posted on 2022-09-26

792 Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Bridi, M.; Luo, N.; Kim, G.; O'Ferrall, C.; Oatel, R.; Bertrand, S.; Kannan, S.; Kirkwood, A.

10.1101/2021.07.05.451213 — neuroscience — Posted on 2022-09-26

793 A reference induced pluripotent stem cell line for large-scale collaborative studies

Pantazis, C. B.; Yang, A.; Lara, E.; McDonough, J. A.; Blauwendraat, C.; Peng, L.; Oguro, H.; Kanaujiya, J.; Zou, J.; Sebesta, D.; Pratt, G.; Cross, E.; Blockwick, J.; Buxton, P.; Kinner-Bibeau, L.; Medura, C.; Tompkins, C.; Hughes, S.; Santiana, M.; Faghri, F.; Nalls, M. A.; Vitale, D.; Ballard, S.; Qi, Y. A.; Ramos, D. M.; Anderson, K. M.; Stadler, J.; Narayan, P.; Papademetriou, J.; Reilly, L.; Nelson, M. P.; Aggarwal, S.; Rosen, L. U.; Kirwan, P.; Pisupati, V.; Coon, S. L.; Scholz, S. W.; Priebe, T.; Öttl, M.; Dong, J.; Meijer, M.; Janssen, L. J. M.; Lourenco, V. S.; van der Kant, R.; Cru

10.1101/2021.12.15.472643 — neuroscience — Posted on 2022-09-26

794 An integrase toolbox to record gene-expression during plant development.

Guiziou, S.; Maranas, C. J.; Chu, J. C.; Nemhauser, J. L.

10.1101/2022.09.16.508262 — synthetic biology — Posted on 2022-09-26

795 Structure-based identification of novel histone deacetylase 4 (HDAC4) inhibitors

Agarwal, R.; Pattarawat, P.; Duff, M. R.; Wang, H.-C. R.; Baudry, J.; Smith, J.

10.1101/2022.05.31.494169 — cancer biology — Posted on 2022-09-26

796 Active muscular hydraulics

Shankar, S.; Mahadevan, L.

10.1101/2022.02.20.481216 — biophysics — Posted on 2022-09-26

797 Meta-analysis of the public RNA-Seq data of the Western honeybee Apis mellifera to construct reference transcriptome data

Yokoi, K.; Wakamiya, T.; Bono, H.

10.1101/2022.09.07.506879 — bioinformatics — Posted on 2022-09-26

798 Rapid adaptation and range expansion in response to agriculture over the last two centuries

Kreiner, J. M.; Latorre, S. M.; Burbano, H. A.; Stinchcombe, J. R.; Otto, S. P.; Weigel, D.; Wright, S. I.

10.1101/2022.02.25.482047 — evolutionary biology — Posted on 2022-09-26

799 The single Marchantia polymorpha FERONIA homolog reveals an ancestral role in regulating cellular expansion and integrity

Mecchia, M. A.; Rovekamp, M.; Giraldo-Fonseca, A.; Meier, D.; Gadient, P.; Vogler, H.; Limacher, D.; Bowman, J.; Grossniklaus, U.

10.1101/2020.12.23.424085 — evolutionary biology — Posted on 2022-09-26

800 Studies on the Escherichia coli ExbD Transmembrane Domain, Residue L132, and an Inhibitory Cyclic Peptide.

Jana, B.; Kopp, D. R.; Xie, M.; Rao, H. V.; Postle, K.

10.1101/2022.09.26.509584 — molecular biology — Posted on 2022-09-26

801 Human NOP2/NSUN1 Regulates Ribosome Biogenesis Through Non-Catalytic Complex Formation with Box C/D snoRNPs.

Liao, H.; Gaur, A.; McConie, H.; Shekar, A.; Wang, K.; Chang, J.; Breton, G.; Denicourt, C.

10.1101/2021.11.12.468419 — molecular biology — Posted on 2022-09-26

802 A small molecule that inhibits the evolution of antibiotic resistance

Johnson, A. E.; Bracey, H.; Viera, A. J. H.; Carvajal-Garcia, J.; Simsek, E. N.; Kim, K.; Merrikh, H.

10.1101/2022.09.26.509600 — microbiology — Posted on 2022-09-26

803 Quantification of the mobility potential of antibiotic resistance genes through multiplexed ddPCR linkage analysis

de la Cruz Barron, M.; Kneis, D.; Elena, A. X.; Bagra, K.; Berendonk, T. U.; Klümper, U.

10.1101/2022.09.26.509453 — microbiology — Posted on 2022-09-26

804 Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest

Munoz-Gutierrez, V.; Cornejo, F. A.; Schmidt, K.; Frese, C. K.; Halte, M.; Erhardt, M.; Elsholz, A. K. W.; Turgay, K.; Charpentier, E.

10.1101/2022.09.20.508806 — microbiology — Posted on 2022-09-26

805 The population-level impact of Enterococcus faecalis genetics on intestinal colonisation and extraintestinal infection

Chaguza, C.; Pöntinen, A. K.; Top, J.; Arredondo-Alonso, S.; Freitas, A. R.; Novais, C.; Torres, C.; Bentley, S. D.; Peixe, L.; Coque, T. M.; Willems, R. J. L.; Corander, J.

10.1101/2022.09.26.509451 — microbiology — Posted on 2022-09-26

806 PBP1A directly interacts with the divisome complex to promote septal peptidoglycan synthesis in Acinetobacter baumannii

Kang, K. N.; Boll, J. M.

10.1101/2022.09.26.509500 — microbiology — Posted on 2022-09-26

807 A monoclonal antibody targeting the Nipah virus fusion glycoprotein apex imparts protection from disease

Avanzato, V. A.; Bushmaker, T.; Oguntuyo, K. Y.; Yinda, K. C.; Duyvesteyn, H. M. E.; Stass, R.; Meade-White, K.; Rosenke, R.; Thomas, T.; Saturday, G.; Doores, K. J.; Lee, B.; Bowden, T.; Munster, V.

10.1101/2022.09.26.507980 — microbiology — Posted on 2022-09-26

808 Multi-factorial examination of amplicon sequencing workflows from sample preparation to bioinformatic analysis

De Wolfe, T. J.; Wright, E. S.

10.1101/2022.09.26.509576 — microbiology — Posted on 2022-09-26

809 Thymic macrophages consist of two populations with distinct localization and origin

Zhou, T.-A.; Hsu, H.-P.; Tu, Y.-H.; Cheng, H.-K.; Lin, C.-Y.; Chen, N.-J.; Tsai, J.-W.; Robey, E. A.; Huang, H.-C.; Hsu, C.-L.; Dzhagalov, I. L.

10.1101/2021.11.04.467238 — immunology — Posted on 2022-09-26

810 Lymphatic dysfunction in lupus contributes to cutaneous photosensitivity and lymph node B cell responses

Ambler, W. G.; Howlander, M.; Chalasani, M. L. S.; Seltzer, E.; Sim, J.; Shin, J.; Schwartz, N.; Shipman, W. D.; Dasoveanu, D.; Carballo, C.; Sevim, E.; Rodeo, S.; Erkan, D.; Kataru, R. P.; Mehrara, B.; Lu, T. T.

10.1101/2022.06.13.495930 — immunology — Posted on 2022-09-26

811 The correlation between antiviral drug, immune response and HIV viral load

Taye, M.; Zhang, S. Y.

10.1101/2020.11.06.372094 — biophysics — Posted on 2022-09-26

812 Allosteric regulation and crystallographic fragment screening of SARS-CoV-2 NSP15 endoribonuclease

Schutzer Godoy, A.; Minalli Nakamura, A.; Douangamath, A.; Song, Y.; Dias Noske, G.; Oliveira Gawriljuk, V.; Sachetto Fernandes, R.; D. Muniz Pereira, H.; Irene Zagato Oliveira, K.; Fearon, D.; Dias, A.; Krojer, T.; Fairhead, M.; Powell, A.; Dunnet, L.; Brandao-Neto, J.; Skyner, R.; Chalk, R.; von Delft, F.; Bajusz, D.; Bege, M.; Borbas, A.; Miklos Keseru, G.; Oliva, G.

10.1101/2022.09.26.509485 — biochemistry — Posted on 2022-09-26

813 SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3

Schindewolf, C.; Lokugamage, K.; Vu, M.; Johnson, B. A.; Scharton, D.; Plante, J. A.; Kalveram, B. K.; Crocquet-Valdes, P. A.; Sotcheff, S. L.; Jaworski, E.; Alvarado, R. E.; Debbink, K.; Daugherty, M. D.; Weaver, S.; Routh, A. L.; Walker, D. H.; Plante, K. S.; Menachery, V. D.

10.1101/2022.09.26.509529 — microbiology — Posted on 2022-09-26

814 Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against Omicron

Chi, X.; Xia, L.; Zhang, G.; Chi, X.; Huang, B.; Zhang, Y.; Chen, Z.; Han, J.; Wu, L.; Li, Z.; Sun, H.; Huang, P.; Yu, C.; Chen, W.; Zhou, Q.

10.1101/2022.09.25.509344 — microbiology — Posted on 2022-09-26

815 Nanobodies for the treatment of SARS-CoV-2 in animals: a meta-analysis

jiao, j.; lin, s. l.; liang, z. q.; Wu, P.

10.1101/2022.09.26.509459 — immunology — Posted on 2022-09-26

816 Zymosan-induced leukocyte and cytokine changes in pigs: a new model for streamlined drug testing against severe COVID-19

Kokeny, G.; Bakos, T.; Barta, B. A.; Nagy, G. V.; Meszaros, T.; Kozma, G. T.; Szabo, A.; Szebeni, J.; Merkely, B.; Radovits, T.

10.1101/2022.09.23.509252 — immunology — Posted on 2022-09-26

817 Spatial transcriptomic profiling of coronary endothelial cells in SARS-CoV-2 myocarditis

Margaroli, C.; Benson, P.; Gastanadui, M. G.; Song, C.; Viera, L.; Xing, D.; Wells, J. M.; Patel, R.; Gaggar, A.; Payne, G. A.

10.1101/2022.09.25.509426 — pathology — Posted on 2022-09-26

818 High-throughput identification of prefusion-stabilizing mutations in SARS-CoV-2 spike

Tan, T. J. C.; Mou, Z.; Lei, R.; Ouyang, W. O.; Yuan, M.; Song, G.; Andrabi, R.; Wilson, I. A.; Kieffer, C.; Dai, X.; Matreyek, K. A.; Wu, N. C.

10.1101/2022.09.24.509341 — biochemistry — Posted on 2022-09-26

819 Analysis of sex differential genes at whole genome level reveals their organ- and chromosome-dependent expressions, regulations, and interactions

Ma, J.; Wang, L.; Yuan, G.; Fernando, C.; Yao, L.; Dong, W.; Tian, C.; Bukiya, A.; Jablonski, M.; Feng, H.; Li, D.; Lu, L.; Jiao, Y.; Ji, J.; Wang, G.; Gu, W.

10.1101/2022.09.24.509319 — cell biology — Posted on 2022-09-26

820 EGFR-initiated endocytosis of Wnt9a and Fzd9b is required for β-catenin signaling

Nguyen, N.; Carpenter, K. A.; Thurlow, K. E.; Mu, E. M.; Gilliland, C.; Grainger, S.

10.1101/2022.09.25.509379 — cell biology — Posted on 2022-09-26

821 Sequencing of Monkeypox virus from infected patients reveals viral genomes with APOBEC3-like editing, gene inactivation, and bacterial agents of skin superinfection

Colson, P.; Penant, G.; Delerce, J.; Boschi, C.; Wurtz, N.; Branger, S.; Lagier, J.-C.; Cassir, N.; Tissot-Dupont, H.; Million, M.; Aherfi, S.; La Scola, B.

10.1101/2022.09.26.509493 — microbiology — Posted on 2022-09-26

822 A pan-variant mRNA-LNP T cell vaccine protects HLA transgenic mice from mortality after infection with SARS-CoV-2 Beta

10.1101/2022.09.23.509206 — immunology — Posted on 2022-09-26

823 PF-D-Trimer, a broadly protective SARS-CoV-2 subunit vaccine: immunogenicity and application

Zhang, Z.; Zhou, J.; Ni, P.; Hu, B.; Deng, S.; Xiao, Q.; He, Q.; Li, G.; Xia, Y.; Liu, M.; Wang, C.; Fang, Z.; Xia, N.; Zhang, Z.-R.; Zhang, B.; Cai, K.; Jolicoeur, N.; Xu, Y.; Liu, B.

10.1101/2022.09.26.509414 — immunology — Posted on 2022-09-26

824 Synchronization of oscillatory growth prepares fungal hyphae for fusion

Wernet, V.; Kumpost, V.; Mikut, R.; Hilbert, L.; Fischer, R.

10.1101/2022.09.25.509415 — cell biology — Posted on 2022-09-26

825 Biophysical and Structural Characterization of a Viral Genome Packaging Motor

Prokhorov, N. S.; Davis, C. R.; Maruthi, K.; Yang, Q.; Woodson, M.; White, M. A.; Miller, L. M.; Jarrold, M. F.; Catalano, C. E.; Morais, M.

10.1101/2022.09.25.509378 — biophysics — Posted on 2022-09-26

826 High-accuracy protein model quality assessment using attention graph neural networks

Zhang, P.-D.; Xia, C.; Shen, H.-B.

10.1101/2022.09.24.509136 — bioinformatics — Posted on 2022-09-26

827 Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes

Zhu, H.; Wang, G.; Nguyen-Ngoc, K.-V.; Kim, D.; Miller, M.; Goss, G.; Kovsky, J.; Harrington, A. R.; Saunders, D.; Melton, R.; Powers, A. C.; Preissl, S.; Spagnoli, F. M.; Gaulton, K. J.; Sander, M.

10.1101/2022.09.25.509355 — cell biology — Posted on 2022-09-26

828 Retrotransposons hijack alt-EJ DNA repair process for mobilization and eccDNA biogenesis

Zhang, Z.; Yang, F.; Su, W.; Chung, O.; Tracy, L.; Wang, L.; Ramsden, D.

10.1101/2022.09.25.509424 — cell biology — Posted on 2022-09-26

829 NBS1 binds directly to TOPBP1 via disparate interactions between the NBS1 BRCT1 domain and the TOPBP1 BRCT1 and BRCT2 domains

Huynh, O.; Ruis, K.; Montales, K.; Michael, W. M.

10.1101/2022.09.26.509489 — cell biology — Posted on 2022-09-26

830 Activity-based directed evolution of a membrane editor in mammalian cells

Tei, R.; Bagde, S. R.; Fromme, J. C.; Baskin, J. M.

10.1101/2022.09.26.509516 — cell biology — Posted on 2022-09-26

831 Cryopreserved cGMP-compliant human pluripotent stem cells-derived immature hepatic progenitors rescue mice from acute liver failure

Gantier, M.; Rispal, R.; Angelique, F.; Menoret, S.; Delbos, F.; Renault, S.; Gary, A.-S.; Anegon, I.; Nguyen, T. H.

10.1101/2022.09.26.509491 — cell biology — Posted on 2022-09-26

832 Separate roles of LMAN1 and MCFD2 in ER-to-Golgi trafficking of factor V and factor VIII

Zhang, Y.; Liu, Z.; Zhang, B.

10.1101/2022.09.25.509417 — cell biology — Posted on 2022-09-26

833 Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction

Xie, S.; Choudhari, S.; Wu, C.-L.; Abramson, K.; Corcoran, D.; Gregory, S. G.; Thimmapuram, J. M.; Guilak, F.; Little, D.

10.1101/2022.09.26.509507 — cell biology — Posted on 2022-09-26

834 MRCK controls myosin II activation in the polarized cortex of mouse oocytes and promotes spindle rotation and male pronucleus centration

Bourdais, A.; Dehapiot, B.; Halet, G.

10.1101/2022.09.25.509421 — cell biology — Posted on 2022-09-26

835 Intravenous administration of human umbilical cord mesenchymal stromal cells leads to an inflammatory response in the lung

Pichardo, A. H.; Wilm, B.; Liptrott, N.; Murray, P.

10.1101/2022.09.26.509547 — cell biology — Posted on 2022-09-26

836 Dysregulation of Acid Ceramidase-mediated Sphingolipid Metabolism Contributes to Tumor Progression in Tuberous Sclerosis Complex

Astrinidis, A.; Li, C.; Zhang, E. Y.; Zhao, X.; Zhao, S.; Guo, M.; Huang, R.; Zhang, A. A.; Kopras, E. J.; Gupta, N.; Smith, E. P.; Fugate, E.; Lindquist, D.; Wikenheiser-Brokamp, K.; Setchell, K. D.; McCormack, F. X.; Xu, Y.; Yu, J. J.

10.1101/2022.09.25.509382 — cell biology — Posted on 2022-09-26

837 FLAIRR-seq: A novel method for single molecule resolution of near full-length immunoglobulin heavy chain repertoires

Ford, E. E.; Tieri, D.; Rodriguez, O. L.; Francoeur, N. J.; Soto, J.; Kos, J. T.; Gibson, W. S.; Silver, C. A.; Deikus, G.; Hudson, E.; Woolley, C. R.; Beckmann, N.; Charney, A.; Mitchell, T. C.; Sebra, R. P.; Watson, C. T.; Smith, M. L.

10.1101/2022.09.24.509352 — immunology — Posted on 2022-09-26

838 Involvement of superior colliculus in complex figure detection of mice

Cazemier, J. L.; Tran, T. K. L.; Hsu, A. T. Y.; Husic, M.; Kirchberger, L.; Self, M. W.; Roelfsema, P. R.; Heimel, J. A.

10.1101/2022.09.25.509365 — neuroscience — Posted on 2022-09-26

839 Cortical miR-709 links glutamatergic signaling to NREM sleep EEG slow waves in an activity-dependent manner

Kompotis, K.; Mang, G.; Hubbard, J. T.; Jimenez, S.; Emmenegger, Y.; Polysopoulos, C.; Hor, C. N.; Wigger, L.; Hebert, S. S.; Mongrain, V.; Franken, P.

10.1101/2022.09.24.508386 — neuroscience — Posted on 2022-09-26

840 On the Geometry of Elementary Flux Modes

Wieder, F.; Henk, M.; Bockmayr, A.

10.1101/2022.09.24.509324 — systems biology — Posted on 2022-09-26

841 Two cyclic electron flows around photosystem I differentially participate in C4 photosynthesis

Ogawa, T.; Kobayashi, K.; Taniguchi, Y. Y.; Shikanai, T.; Nakamura, N.; Yokota, A.; Munekage, Y. N.

10.1101/2022.09.23.509273 — plant biology — Posted on 2022-09-26

842 Deletion of 12-lipoxygenase normalizes platelet function after storage and transfusion in thrombocytopenic mice

Larsen, H.; Byrne, D. A.; Bailey, S.; Stolla, M. C.; Holinstat, M.; Fu, X.; Stolla, M.

10.1101/2022.09.23.509265 — physiology — Posted on 2022-09-26

843 Preponderant Myosin Super-Relaxed State In Skeletal Muscle From Endurance Athletes

Lewis, C. T. A.; Tabrizian, L.; Nielsen, J.; Laitila, J.; Beck, T. N.; Aagaard, P.; Hokken, R.; Laugesen, S.; Ingersen, A.; Andersen, J. L.; Soendenbroe, C.; Helge, J. W.; Dela, F.; Larsen, S.; Sahl, R. E.; Roemer, T.; Hansen, M. T.; Frandsen, J.; Suetta, C.; Ochala, J.

10.1101/2022.09.23.509202 — physiology — Posted on 2022-09-26

844 Design principles of 3D epigenetic memory systems

Owen, J. A.; Osmanovic, D.; Mirny, L. A.

10.1101/2022.09.24.509332 — biophysics — Posted on 2022-09-26

845 End-to-End Differentiable Blind Tip Reconstruction for Noisy Atomic Force Microscopy Images

Matsunaga, Y.; Fuchigami, S.; Ogane, T.; Takada, S.

10.1101/2022.09.24.509314 — biophysics — Posted on 2022-09-26

846 Where the Minor Things Are: A Survey of Minor Spliceosomal Introns in Thousands of Eukaryotic Genomes

Larue, G. E.; Roy, S. W.

10.1101/2022.09.24.509304 — bioinformatics — Posted on 2022-09-26

847 GPCRome-wide structural analysis of G-protein-coupling selectivity

Matic, M.; Miglionico, P.; Inoue, A.; Raimondi, F.

10.1101/2022.09.24.508774 — bioinformatics — Posted on 2022-09-26

848 Contractile work and biarticular mechanisms of the triceps surae muscles facilitate net ankle mechanical work at high walking speeds

Kharazi, M.; Bohm, S.; Theodorakis, C.; Mersmann, F.; Arampatzis, A.

10.1101/2022.09.24.507845 — bioengineering — Posted on 2022-09-26

849 Inter-organelle crosstalk supports acetyl-coenzyme A homeostasis and lipogenesis under metabolic stress

Metallo, C.; Kumar, A.; Kuna, R. S.; Galvez, H.; Wessendorf-Rodriguez, K. A.; Green, C. R.; McGregor, G. H.; Cordes, T.; Shaw, R. J.; Svensson, R. U.

10.1101/2022.09.24.509326 — bioengineering — Posted on 2022-09-26

850 EVIDENCE FOR EMPATHY IN PAIR BONDING POISON FROGS

Nowicki, J. P.; Rodriguez, C.; Lee, J. C.; Goolsby, B. C.; Yang, C.; Cleland, T. A.; O'Connell, L. A.

10.1101/2022.09.25.509360 — animal behavior and cognition — Posted on 2022-09-26

851 Ecological change and conflict reduction led to the evolution of a transformative social behavior in ants

Meurville, M.-P.; Silvestro, D.; LeBoeuf, A. C.

10.1101/2022.09.25.509371 — evolutionary biology — Posted on 2022-09-26

852 Gills, growth, and activity across fishes

Bigman, J. S.; Wegner, N. C.; Dulvy, N. K.

10.1101/2022.09.24.509310 — ecology — Posted on 2022-09-26

853 Viral proteins and virus-like particles of the LTR5_Hs endogenous retrovirus in human primordial germ cell-like cells

Kobayashi, M.; Kobayashi, M.; Kreuzer, J.; Zaniewski, E.; Kim, J. J.; Shioda, K.; Hagihara, H.; Odajima, J.; Nakashoji, A.; Zheng, Y.; Fu, J.; Ericsson, M.; Kawamura, K.; Stott, S. L.; Irimi, D.; Haas, W.; Wu, C.-L.; Tokuyama, M.; Shioda, T.

10.1101/2022.09.24.509338 — developmental biology — Posted on 2022-09-26

854 The carnitine shuttle links mitochondrial metabolism to histone acetylation and lipogenesis

Izzo, L. T.; Trefely, S.; Demetriadou, C.; Drummond, J.; Mizukami, T.; Kuprasertkul, N.; Farria, A.; Nguyen, P.; Reich, L.; Shaffer, J.; Affronti, H.; Carrer, A.; Andrews, A.; Capell, B. C.; Snyder, N. W.; Wellen, K. E.

10.1101/2022.09.24.509197 — cell biology — Posted on 2022-09-26

855 Engineering non-cytotoxic delivery of proteins by T cells via fusion to NPC2

Saeedi, A.; Bandey, I. N.; Leekha, A.; Fathi, M.; Rezvan, A.; Montalvo, M. J.; Wu, K.-L.; Bohat, R.; Peng, W.; Varadarajan, N.

10.1101/2022.09.24.509028 — immunology — Posted on 2022-09-26

856 Mitochondria dysregulation contributes to secondary neurodegeneration progression post-contusion injury in human 3D in vitro triculture brain tissue model.

Liaudanskaya, V.; Fiore, N. J.; Zhang, Y.; Milton, Y.; Kelly, M. F.; Coe, M.; Barreiro, A.; Rose, V. K.; Shapiro, M. R.; Mullis, A. S.; Shevzov-Zebrun, A.; Blurton-Jones, M.; Whalen, M. J.; Symes, A. J.; Georgakoudi, I.; Nieland, T. J.; Kaplan, D. L.

10.1101/2022.09.23.509276 — neuroscience — Posted on 2022-09-26

857 A texture statistics encoding model reveals hierarchical feature selectivity across human visual cortex

Henderson, M. M.; Tarr, M. J.; Wehbe, L.

10.1101/2022.09.23.509292 — neuroscience — Posted on 2022-09-26

858 Reduced Thalamic Excitation to Motor Cortical Pyramidal Tract Neurons in a Mouse Model of Parkinsonism

Chen, L.; Daniels, S.; Dvorak, R.; Chu, H.-y.

10.1101/2022.09.24.509340 — neuroscience — Posted on 2022-09-26

859 The impact of Mmu17 non-Hsa21 orthologous genes in the Ts65Dn mouse model of Down syndrome: the "gold standard" revisited

Guedj, F.; Kane, E.; Bishop, L.; Pennings, J. L. A.; Herault, Y.; Bianchi, D. W.

10.1101/2022.09.23.509067 — neuroscience — Posted on 2022-09-26

860 Tug-of-peace: Visual Rivalry and Atypical Visual Motion Processing in MECP2 Duplication Syndrome of Autism

Bogatova, D.; Smirnakis, S.; Palagina, G.

10.1101/2022.09.23.509144 — neuroscience — Posted on 2022-09-26

861 Small-molecule ketone esters treat brain network abnormalities in an Alzheimer's disease mouse model

Newman, J. C.; Ma, K.; Kroll, F.; Higgins, E.; Ulrich, S.; Palop, J. J.; Verdin, E.

10.1101/2022.09.24.509337 — neuroscience — Posted on 2022-09-26

862 Cell type specific transcriptomic differences in depression show similar patterns between males and females but implicate distinct cell types and genes

Maitra, M.; Mitsuhashi, H.; Rahimian, R.; Chawla, A.; Yang, J.; Fiori, L.; Davoli, M.-A.; Perlman, K.; Aouabed, Z.; Mash, D. C.; Suderman, M.; Mechawar, N.; Turecki, G.; Nagy, C.

10.1101/2022.09.23.509254 — neuroscience — Posted on 2022-09-26

863 Microglia are involved in regulating histamine dependent and non-dependent itch transmissions with distinguished signal pathways

Yang, Y.; Mou, B.; Zhang, Q.-R.; Zhao, H.-X.; Zhang, J.-Y.; Yun, X.; Xiong, M.-T.; Liu, Y.; Liu, Y. U.; Pan, H.; Ma, C.-L.; Li, B.-M.; Peng, J.

10.1101/2022.09.23.498040 — neuroscience — Posted on 2022-09-26

864 Overlapping Neural Representations for Dynamic Visual Imagery and Stationary Storage in Spatial Working Memory

Günseli, E.; Foster, J.; Sutterer, D.; Todorova, L.; Vogel, E. K.; Awh, E.

10.1101/2022.09.24.509255 — neuroscience — Posted on 2022-09-26

865 Depletion of collagen IX alpha2 interferes osteochondral homeostasis of the knee joint which ultimately causing osteoarthritis-like articular cartilage damage

Dong, R.; Xu, H.; Wang, P.; Fang, L.; Xiao, L.; Lv, S.; Tong, P.; Jin, H.

10.1101/2022.09.24.509343 — physiology — Posted on 2022-09-26

866 Scaffold and structural diversity of the secondary metabolite space of medicinal fungi

Vivek-Ananth, R. P.; Sahoo, A. K.; Baskaran, S. P.; Samal, A.

10.1101/2022.09.25.509364 — pharmacology and toxicology — Posted on 2022-09-26

867 Impact of clonal architecture on clinical course and prognosis in patients with myeloproliferative neoplasms

Luque Paz, D.; Bader, M. S.; Nienhold, R.; Rai, S.; Almeida Fonseca, T.; Stetka, J.; Hao-Shen, H.; Mild-Schneider, G.; Passweg, J. R.; Skoda, R. C.

10.1101/2022.09.24.509318 — cancer biology — Posted on 2022-09-26

868 Disruptions in cell fate decisions and transformed enteroendocrine cells drive intestinal tumorigenesis in Drosophila.

Quintero, M.; Bangi, E.

10.1101/2022.09.25.509404 — cancer biology — Posted on 2022-09-26

869 Structural and Dynamical Properties of Elastin-Like Peptides near their Lower Critical Solution Temperature

Morozova, T. I.; Garcia, N. A.; Matsarskaia, O.; Roosen-Runge, F.; Barrat, J.-L.

10.1101/2022.09.25.509363 — biophysics — Posted on 2022-09-26

870 Reconstructing the transport cycle in the sugar porter superfamily using coevolution-powered machine learning

Mitrovic, D.; McComas, S. E.; Alleva, C.; Bonaccorsi, M.; Drew, D.; Delemotte, L.

10.1101/2022.09.24.509294 — biophysics — Posted on 2022-09-26

871 Amino acid sequence assignment from single molecule peptide sequencing data using a two-stage classifier

Smith, M. B.; Simpson, Z. B.; Marcotte, E. M.

10.1101/2022.09.23.509260 — bioinformatics — Posted on 2022-09-26

872 MSstatsPTM: Statistical relative quantification of post-translational modifications in bottom-up mass spectrometry-based proteomics

Kohler, D.; Tsai, T.-H.; Verschueren, E.; Huang, T.; Hinkle, T.; Phu, L.; Choi, M.; Vitek, O.

10.1101/2022.09.24.509068 — bioinformatics — Posted on 2022-09-26

873 3D-printed capillaric ELISA-on-a-chip with aliquoting

Parandakh, A.; Ymbern, O.; Jogia, W.; Renault, J.; Ng, A.; Juncker, D.

10.1101/2022.09.23.508398 — bioengineering — Posted on 2022-09-26

874 VOCAL SIMILARITY AND DIFFERENCES IN FOUR SPECIES OF THE GENUS ANTHUS: IMPLICATION ON COMMUNICATION AND TAXONOMIC RELATEDNESS

Dragonetti, M.

10.1101/2022.09.25.509367 — animal behavior and cognition — Posted on 2022-09-26

875 FLOCK STASIS DRIVES FLYING SPEED IN PIGEONS, WHILE ARTIFICIAL MASS ADDITIONS DO NOT

Portugal, S.; Sankey, D. W.

10.1101/2022.09.24.509309 — animal behavior and cognition — Posted on 2022-09-26

876 Global observation of plankton communities from space

Kaneko, H.; Endo, H.; Henry, N.; Berney, C.; Mahe, F.; Poulain, J.; Labadie, K.; Beluche, O.; El Hourany, R.; Tara Oceans Coordinators, ; Chaffron, S.; Wincker, P.; Nakamura, R.; Karp-Boss, L.; Boss, E.; Bowler, C.; de Vargas, C.; Tomii, K.; Ogata, H.; Acinas, S. G.; Babin, M.; Bork, P.; Cochrane, G.; Gorsky, G.; Guidi, L.; Grimsley, N.; Hingamp, P.; Iudicone, D.; Jaillon, O.; Kandels, S.; Karsenti, E.; Not, F.; Poulton, N.; Pesant, S.; Sardet, C.; Speich, S.; Stemmann, L.; Sullivan, M. B.; Sunagawa, S.

10.1101/2022.09.23.508961 — ecology — Posted on 2022-09-26

877 Multiplatform Modeling of Atrial Fibrillation Identifies Phospholamban as Central Regulator of Cardiac Rhythm

Colas, A.; Ocorr, K.; Grandi, E.; Andersen, P.; Kannan, S.; Spiering, S.; Yu, M.; Ni, H.; Kezos, J.; Kervadec, A.

10.1101/2022.09.23.509238 — pathology — Posted on 2022-09-26

878 Extending Comparison Methods for Unsigned Networks to Signed Networks

Krinsman, W. E.

10.1101/2022.09.23.509251 — bioinformatics — Posted on 2022-09-26

879 Models of Throughput for Multi-Cell, Multi-Type Droplet Microfluidics

Krinsman, W. E.

10.1101/2022.09.23.509249 — bioinformatics — Posted on 2022-09-26

880 Huntington's disease phenocopy syndromes revisited: a clinical comparison and next-generation sequencing exploration

Koriath, C. A. M.; Guntotoi, F.; Norseworthy, P.; Dolzhenko, E.; Eberle, M. A.; Hensman Moss, D. J.; Flower, M.; Hummerich, H.; Rosser, A. E.; Tabrizi, S. J.; Mead, S. H.; Wild, E.

10.1101/2022.09.23.509161 — genetics — Posted on 2022-09-26

881 Mating strategies in Caenorhabditis elegans populations are determined by male developmental history

Al-Saadi, R. S.; Luo, J.; Nichitean, A. M.; Wagner, N. R.; Portman, D. S.; Hall, S. E.

10.1101/2022.09.23.509199 — genetics — Posted on 2022-09-26

882 Selection leads to remarkable variability in the outcomes of hybridization across replicate hybrid zones

McFarlane, S. E.; Jahner, J. P.; Lindtke, D.; Buerkle, C. A.; Mandeville, E. G.

10.1101/2022.09.23.509250 — evolutionary biology — Posted on 2022-09-26

883 Seasonal stability and species specificity of environmentally acquired chemical mating signals in orchid bees

Darragh, K.; Linden, T. A.; Ramirez, S. R.

10.1101/2022.09.23.509236 — evolutionary biology — Posted on 2022-09-26

884 Changes in capture availability due to infection can lead to correctable biases in population-level infectious disease parameters

Holmes, I. A.; Durso, A. M.; Myers, C. R.; Hendry, T. A.

10.1101/2022.09.23.509235 — ecology — Posted on 2022-09-26

885 High-resolution profiling of neoantigen-specific T cell receptor activation signatures links moderate stimulation patterns to resilience and sustained tumor control

Füchsl, F.; Untch, J.; Kavaka, V.; Jarosch, S.; Vogelsang, C.; de Andrade Krätzig, N.; Gosmann, D.; Rad, R.; Busch, D. H.; Beltran, E.; Bräunlein, E.; Krackhardt, A. M.

10.1101/2022.09.23.508529 — immunology — Posted on 2022-09-26

886 Combination Ad26.RSV.preF/RSV preF protein vaccine induces superior humoral, cellular, and protective immunity compared with individual vaccine components in preclinical models

Saeland, E.; van der Fits, L.; Bolder, R.; Heemskerk-van der Meer, M.; Drijver, J.; van Polanen, Y.; Vaneman, C.; Tettero, L.; Cox, F.; Serroyen, J.; Jorgensen, M. J.; Langedijk, J. P. M.; Schuitemaker, H.; Callendret, B.; Zahn, R. C.

10.1101/2022.09.23.509196 — immunology — Posted on 2022-09-26

887 Neurophysiological basis of hemodynamic responses in the developing human brain before the time of normal birth

Poppe, T.; Willers Moore, J.; Rupawala, M.; Price, A. N.; Godinez, F.; Whitehead, K.; Dall'Orso, S.; Edwards, D.; Fabrizi, L.; Arichi, T.

10.1101/2022.09.23.509234 — neuroscience — Posted on 2022-09-26

888 A linear discriminant analysis model of imbalanced associative learning in the mushroom body compartment

Lipshutz, D.; Kashalikar, A.; Farashahi, S.; Chklovskii, D. B.

10.1101/2022.09.23.508775 — neuroscience — Posted on 2022-09-26

889 Mouse paralaminar amygdala excitatory neurons migrate and mature during adolescence

Alderman, P. J.; Saxon, D.; Torrijos-Saiz, L. I.; Sharief, M.; Biagiotti, S. W.; Page, C. E.; Melamed, A.; Kuo, C. T.; Garcia-Verdugo, J.-M.; Herranz-Perez, V.; Corbin, J. G.; Sorrells, S. F.

10.1101/2022.09.23.509244 — neuroscience — Posted on 2022-09-26

890 Water exchange rates measure active transport and homeostasis in neural tissue

Williamson, N. H.; Ravin, R.; Cai, T.; Falgairolle, M.; O'Donovan, M.; Basser, P.

10.1101/2022.09.23.483116 — neuroscience — Posted on 2022-09-26

891 On biological networks capable of robust adaptation in the presence of uncertainties: A systems-theoretic approach

Bhattacharya, P.; Raman, K.; Tangirala, A. K.

10.1101/2022.09.23.509157 — systems biology — Posted on 2022-09-26

892 Comparative Study between In-silico and Clinical Works on the Control of Blood Glucose Level in People with Type 1 Diabetes using Improved Hovorka Equations

Som, A. M.; Mohd Sohadi, N. A.; Mohd Nor, N. S.; Ali, S. A.; Ahmad, M. A.

10.1101/2022.09.23.509189 — systems biology — Posted on 2022-09-26

893 Diel fluctuations in in-vivo SnRK1 activity in Arabidopsis rosettes during light-dark cycles

Avidan, O.; Alexandre Moraes, T.; Mengin, V.; Feil, R.; Rolland, F. A.; Stitt, M.; Lunn, J. E.

10.1101/2022.09.23.509272 — plant biology — Posted on 2022-09-26

894 Leaf traits predict water-use efficiency in U.S. Pacific Northwest grasslands under rain exclusion treatment

Dawson, H. R.; Maxwell, T. M.; Reed, P. B.; Bridgham, S.; Silva, L. C. R.

10.1101/2022.09.23.509243 — plant biology — Posted on 2022-09-26

895 Cadmium treatment induces endoplasmic reticulum stress and unfolded protein response in Arabidopsis thaliana

De Benedictis, M.; Gallo, A.; Migoni, D.; Papadia, P.; Roversi, P.; Santino, A.

10.1101/2022.09.23.509148 — plant biology — Posted on 2022-09-26

896 Cuticular wax, but not the cutin matrix, is renewed during the lifespan of Clusia rosea leaves13CO2 labelling and gas exchange study

Kubasek, J.; Kalistova, T.; Janova, J.; Askanbayeva, B.; Bednar, J.; Santrucek, J.

10.1101/2022.09.26.509460 — plant biology — Posted on 2022-09-26

897 Foliar application of preparations as a method of protecting plants from the penetration of lead

Wierzbicka, M.; Bodzon, K.; Nazieblo, A.; Tarnawska, Z.; Wrobel, M.

10.1101/2022.09.23.509154 — plant biology — Posted on 2022-09-26

898 Cell cycle dynamics and window of MUTE action during the terminal division of stomata and ramification of its loss-of-function on the cell cycle of an uncommitted precursor

Zuch, D. T.; Herrmann, A.; Kim, E.-D.; Torii, K. U.

10.1101/2022.09.25.509410 — plant biology — Posted on 2022-09-26

899 Genome-wide association study of water use patterns of common bean (Phaseolus vulgaris L.) genotypes in response to drying soil

Cordoba-Novoa, H. A.; Kelly, J. D.; Hoyos-Villegas, V.

10.1101/2022.09.23.509270 — plant biology — Posted on 2022-09-26

900 Genome-wide investigation of Cytochrome P450 superfamily of Aquilaria agallocha: association with terpenoids and phenylpropanoids biosynthesis

Das, A.; Begum, K.; Akhtar, S.; Ahmed, R.; Tamuli, P.; Kulkarni, R.; Banu, S.

10.1101/2022.09.26.509443 — plant biology — Posted on 2022-09-26

901 Supercharged PGR5-dependent cyclic electron transfer compensates for mis-regulated chloroplast ATP synthase

Degen, G. E.; Jackson, P. J.; Proctor, M. S.; Zoulias, N.; Casson, S.; Johnson, M. P.

10.1101/2022.09.25.509416 — plant biology — Posted on 2022-09-26

902 The trans-zeatin-type side-chain modification of cytokinins controls rice growth

Kiba, T.; Mizutani, K.; Nakahara, A.; Takebayashi, Y.; Kojima, M.; Hobo, T.; Osakabe, Y.; Osakabe, K.; Sakakibara, H.

10.1101/2022.09.25.509405 — plant biology — Posted on 2022-09-26

903 The genomes of medicinal skullcaps reveal the polyphyletic origins of clerodane diterpene biosynthesis in the family Lamiaceae.

Li, H.; Wu, S.; Lin, R.; Xiao, Y.; Malaco Morotti, A. L.; Wang, Y.; Huang, T.; Zhao, Y.; Zhou, X.; Yang, J.; Zhao, Q.; Kanellis, A.; Martin, C.; Tatsis, E.

10.1101/2022.09.25.509435 — plant biology — Posted on 2022-09-26

904 Hydraulic tradeoffs underlie enhanced performance of polyploid trees under soil water scarcity

Losada, J. M.; Blanco-Moure, N.; Fonolla, A.; Martinez-Ferri, E.; Hormaza, J. I.

10.1101/2022.09.24.509308 — plant biology — Posted on 2022-09-26

905 Genome-wide association studies of seed metabolites identify loci controlling specialized metabolites in Arabidopsis thaliana

Naake, T.; Scossa, F.; Perez de Souza, L.; Borghi, M.; Brotman, Y.; Mori, T.; Nakabayashi, R.; Tohge, T.; Fernie, A. R.

10.1101/2022.09.23.509130 — plant biology — Posted on 2022-09-26

906 The giant diploid faba genome unlocks variation in a global protein crop

Jayakodi, M.; Golicz, A. A.; Kreplak, J.; Fechete, L. I.; Angra, D.; Bednar, P.; Bornhofen, E.; Zhang, H.; Boussageon, R.; Kaur, S.; Cheung, K.; Cizkova, J.; Gundlach, H.; Hallab, A.; Imbert, B.; Keeble-Gagnere, G.; Koblizkova, A.; Kobrlova, L.; Krejci, P.; Mouritzen, T. W.; Neumann, P.; Nadzieja, M.; Nielsen, L. K.; Novak, P.; Orabi, J.; Padmarasu, S.; Robertson-Shersby-Harvie, T.; Robledillo, L. A.; Schiemann, A.; Tanskanen, J.; Toronen, P.; Warsame, A. O.; Wittenberg, A. H. J.; Himmelbach, A.; Aubert, G.; Courty, P.-E.; Dolezel, J.; Holm, L. U.; Janss, L. L.; Khazaei, H.; Macas, J.; Mascher

10.1101/2022.09.23.509015 — plant biology — Posted on 2022-09-26

907 Mapping of the Classical Mutation rosette Highlights a Role for Calcium in Wound-induced Rooting

Modrego, A.; Pasternak, T.; Omary, M.; Albacete, A.; Cano, A.; Perez-Perez, J. M.; Efroni, I.

10.1101/2022.09.24.509321 — plant biology — Posted on 2022-09-26

908 Genetic Analysis of Activin/Inhibin β Subunits in Zebrafish Development and Reproduction

Zhao, C.; Zhai, Y.; Geng, R.; Wu, K.; Song, W.; Ai, N.; Ge, W.

10.1101/2022.09.23.509125 — physiology — Posted on 2022-09-26

909 Predicting treatment outcome using kinome activity profiling in HER2+ breast cancer biopsies

Debets, D. O.; de Graaf, E. L.; Liefaard, M. C.; Sonke, G. S.; Lips, E.; Ressa, A.; Altelaar, M.

10.1101/2022.09.23.508980 — cancer biology — Posted on 2022-09-26

910 Towards overtreatment-free immunotherapy: Using genomic scars to select treatment beneficiaries in lung cancer

Donker, H. C.; van Es, B.; Tamminga, M.; Lunter, G. A.; van Kempen, L. C. L. T.; Schuuring, E.; Hiltermann, T. J. N.; Groen, H. J. M.

10.1101/2022.09.23.509152 — cancer biology — Posted on 2022-09-26

911 Benchmarking Oxford Nanopore Read Alignment-Based Structural Variant Detection Tools in Crop Plant Genomes

Yildiz, G.; Zanini, S. F.; Afsharyan, N. P.; Obermeier, C.; Snowdon, R. J.; Golicz, A. A.

10.1101/2022.09.23.508909 — bioinformatics — Posted on 2022-09-26

912 HaploCart: Human mtDNA Haplogroup Classification Using a Pangenomic Reference Graph

Rubin, J. D.; Vogel, N. A.; Gopalakrishnan, S.; Sackett, P. W.; Renaud, G.

10.1101/2022.09.23.509203 — bioinformatics — Posted on 2022-09-26

913 Learning Spatially-Aware Representations of Transcriptomic Data via Transfer Learning

Hao, M.; Wei, L.; Zhang, X.

10.1101/2022.09.23.509186 — bioinformatics — Posted on 2022-09-26

914 Comparing Long Read Fusion Callers using Simulated Read Data

Van Twisk, D.; Rubinsteyn, A.; Vincent, B.

10.1101/2022.09.23.509226 — bioinformatics — Posted on 2022-09-26

915 Bioinformatic-based identification of 3 immune-related genes for prognostic in breast invasive carcinoma

Cui, X.; Song, S.; Zhang, W.; Wang, D.; Fang, Z.

10.1101/2022.09.23.509179 — bioinformatics — Posted on 2022-09-26

916 Bio-Aurac an open-source browser plugin to better navigate literature content.

Evans, A. J.; Etherington, N. E. J.; Laing, M. P.; Rollings, B.; Sweeton, M. J.; Whitehorn, A. J.; Southan, C.; Holliday, G. L.; Jimenez, R. C.; Dunlop, I. W.

10.1101/2022.09.23.508995 — biochemistry — Posted on 2022-09-26

917 Odor-gated oviposition behavior in an ecological specialist

Alvarez-Ocana, R.; Shahandeh, M. P.; Ray, V.; Auer, T. O.; Gompel, N.; Benton, R.

10.1101/2022.09.23.509164 — animal behavior and cognition — Posted on 2022-09-26

918 Gaze following in Archosauria: Alligators and palaeognath birds suggest dinosaur origin of visual perspective taking

Zeitraeg, C.; Reber, S. A.; Osvath, M.

10.1101/2022.09.23.509198 — animal behavior and cognition — Posted on 2022-09-26

919 Allele-specific expression reveals genetic drivers of tissue regeneration in mice

Talbott, H. E.; Mack, K. L.; Griffin, M.; Guardino, N. J.; Parker, J. B.; Spielman, A. F.; Davitt, M. F.; Mascharak, S.; Berger, M. J.; Wan, D. C.; Fraser, H. B.; Longaker, M. T.

10.1101/2022.09.23.509223 — genomics — Posted on 2022-09-26

920 Establishment of porcine ovarian follicles treated with t-BHP for an in vitro aging model

Shi, P.; Gao, J.; Zhao, S.; Xia, W.; Li, J.; Tao, C.

10.1101/2022.09.23.509190 — genetics — Posted on 2022-09-26

921 Genes and sites under adaptation at the phylogenetic scale also exhibit adaptation at the population-genetic scale

Latrille, T.; Rodrigue, N.; Lartillot, N.

10.1101/2022.09.23.509132 — evolutionary biology — Posted on 2022-09-26

922 Rapid expansion and visual specialization of learning and memory centers in Heliconiini butterflies

Couto, A.; Young, F. J.; Atzeni, D.; Marty, S.; Melo-Florez, L.; Hebberecht, L.; Monllor, M.; Neal, C.; Cicconardi, F.; McMillan, W. O.; Montgomery, S. H.

10.1101/2022.09.23.509163 — evolutionary biology — Posted on 2022-09-26

923 Genetic risk for Multiple Sclerosis originated in Pastoralist Steppe populations

Barrie, W.; Yang, Y.; Attfield, K. E.; Irving-Pease, E.; Scorrano, G.; Jensen, L. T.; Armen, A. P.; Dimopoulos, E. A.; Stern, A.; Refoyo-Martinez, A.; Ramsoe, A.; Gaunitz, C.; Demeter, F.; Jorkov, M. L. S.; Moller, S. B.; Springborg, B.; Klassen, L.; Hyldgard, I. M.; Wickmann, N.; Vinner, L.; Korneliussen, T. S.; Allentoft, M. E.; Sikora, M.; Kristiansen, K.; Rodriguez, S.; Nielsen, R.; Iversen, A. K. N.; Lawson, D. J.; Fugger, L.; Willerslev, E.

10.1101/2022.09.23.509097 — evolutionary biology — Posted on 2022-09-26

924 Demography-environment relationships improve mechanistic understanding of range dynamics under climate change

Malchow, A.-K.; Hartig, F.; Reeg, J.; Kery, M.; Zurell, D.

10.1101/2022.09.23.509134 — ecology — Posted on 2022-09-26

925 Bill shape imposes biomechanical tradeoffs in cavity-excavating birds

Chhaya, V.; Reddy, S.; Krishnan, A.

10.1101/2022.09.23.509155 — ecology — Posted on 2022-09-26

926 MegaFeed: Global database of megaherbivores' feeding preferences

Berzaghi, F.; Awasthi, B.

10.1101/2022.09.23.509174 — ecology — Posted on 2022-09-26

927 Immune-related molecular changes in the olfactory epithelium, structural alteration in the olfactory bulb, and psychosis

Yang, K.; Hasegawa, Y.; Hua, J.; Dower, M.; Etyemez, S.; Prasad, N.; Duvall, L. G.; Paez, A. K.; Smith, A.; Lane, A. P.; Ishizuka, K.; Kamath, V.; Kamiya, A.; Sawa, A.

10.1101/2022.09.23.509224 — molecular biology — Posted on 2022-09-26

928 Inhibition of Phosphodiesterase 12 results in Antiviral Activity against several RNA Viruses including SARS-CoV-2.

Karayiannis, P.; Thursz, M.; Sadiq, F.; Tree, J.; Beasley, D.; Dejnirattisai, W.; Mongkolsapaya, J.; Screaton, G.; Wand, M.; Elmore, M.; Miles, C.; Matthews, I.; Thomas, H.

10.1101/2022.09.23.509178 — microbiology — Posted on 2022-09-26

929 Marginal Zone B cells are Necessary for the Formation of Anti-Donor IgG After Allogeneic Sensitization

Kallarakal, M. A.; Cohen, G.; Ibukun, F. I.; Krummey, S.

10.1101/2022.09.23.509210 — immunology — Posted on 2022-09-26

930 PKB/AKT attenuates Lewy Body-like pathology in primary neurons via Cathepsins B and D

Konovalova, J.; Er, S.; Barut, J.; Rafa-Zablocka, K.; Luk, K.; Figiel, M.; Airavaara, M.; Domanskyi, A.; Chmielarz, P.

10.1101/2022.09.23.508066 — neuroscience — Posted on 2022-09-26

931 AAV-delivered gene editing for latent genital or orofacial herpes simplex virus infection reduces ganglionic viral load and minimizes subsequent viral shedding in mice

Aubert, M.; Haick, A. K.; Strongin, D. E.; Klouser, L. M.; Loprieno, M. A.; Stensland, L.; Santo, T. K.; Huang, M.-l.; Hyrien, O.; Stone, D.; Jerome, K. R.

10.1101/2022.09.23.509057 — neuroscience — Posted on 2022-09-26

932 Leveraging vision to understand curiosity

Cohanpour, M.; Aly, M.; Gottlieb, J.

10.1101/2022.09.23.509220 — neuroscience — Posted on 2022-09-26

933 RGA1 alleviates low-light-repressed pollen tube growth by improving the metabolism and allocation of sugars and energy

Li, H.; Feng, B.; Li, J.; Fu, W.; Wang, W.; Chen, T.; Liu, L.; Wu, Z.; Peng, S.; Tao, L.; Fu, G.

10.1101/2022.09.25.509406 — plant biology — Posted on 2022-09-26

934 Characterization of sub-tropical maize (Zea Mays L.) inbred lines for the variation in kernel row numbers (KRN)

Mukri, G.; Gadag, R. N.; Bhat, J. S.; Nepolean, T.; Gupta, N. C.; Mittal, S.; ML, N.; Kumar, R.; Pal, D.

10.1101/2022.09.23.509129 — plant biology — Posted on 2022-09-26

935 CURLYLEAF is a key modulator of apoplast water status in Arabidopsis leaf

Xin, X.-F.; Wu, J.; Zhang, J.; Mei, X.; Wang, Y.; Ye, L.; Chen, T.; Liu, M.; Zhang, Y.

10.1101/2022.09.23.509124 — plant biology — Posted on 2022-09-26

936 A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0

Zivanov, J.; Oton, J.; Ke, Z.; von Kügelgen, A.; Pyle, E.; Qu, K.; Morado, D.; Castano-Diez, D.; Zanetti, G.; Bharat, T.; Briggs, J.; Scheres, S.

10.1101/2022.02.28.482229 — biophysics — Posted on 2022-09-26

937 SARS-CoV-2 spike opening dynamics and energetics reveal the individual roles of glycans and their collective impact

Pang, Y. T.; Acharya, A.; Lynch, D.; Pavlova, A.; Gumbart, J.

10.1101/2021.08.12.456168 — biophysics — Posted on 2022-09-26

938 Kokiri: Random-Forest-Based Comparison and Characterization of Cohorts

Eckelt, K.; Adelberger, P.; Bauer, M. J.; Zichner, T.; Streit, M.

10.1101/2022.08.16.503622 — bioinformatics — Posted on 2022-09-26

939 The Effect of Oblique Image Acquisition on the Accuracy of Quantitative Susceptibility Mapping and a Robust Tilt Correction Method

Kiersnowski, O. C.; Karsa, A.; Wastling, S. J.; Thornton, J. S.; Shmueli, K.

10.1101/2021.11.30.470544 — bioengineering — Posted on 2022-09-26

940 Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Nguyen, A.; Lugarini, F.; David, C.; Hosnani, P.; Knotkova, B.; Patel, A.; Parfentev, I.; Friedrich, A.; Urlaub, H.; Meinecke, M.; Stork, B.; Faesen, A.

10.1101/2022.09.21.508836 — biochemistry — Posted on 2022-09-26

941 Disentangling the roles of inter and intraspecific variation on leaf trait distributions across the eastern United States

Marconi, S.; Weinstein, B. G.; Lichstein, J. W.; Bohlman, S. A.; Singh, A.; White, E. P.

10.1101/2021.04.01.438064 — ecology — Posted on 2022-09-26

942 Large-scale analysis and computer modeling reveal hidden regularities behind variability of cell division patterns in Arabidopsis thaliana embryogenesis

Laruelle, E.; Belcram, K.; Trubuil, A.; Palauqui, J.-C.; Andrey, P.

10.1101/2022.03.23.483962 — developmental biology — Posted on 2022-09-26

943 Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

Zhu, Z.; Tovey, C. A.; Yen, E. C.; BERNARD, F.; Guichet, A.; Conduit, P. T.

10.1101/2022.09.23.509043 — cell biology — Posted on 2022-09-26

944 Environmental regulation of gene expression mediated by Long non-coding RNAs

Kang, J.; Chung, A.; Suresh, S.; Bonzi, L. C.; Sourisse, J. M.; Ramirez-Calero, S.; Romeo, D.; Petit-Marty, N.; Pegueroles, C.; Schunter, C.

10.1101/2022.06.17.496488 — molecular biology — Posted on 2022-09-26

945 Pyramidal cell types drive functionally distinct cortical activity patterns during decision-making

Musall, S.; Sun, X. R.; Mohan, H.; An, X.; Gluf, S.; Li, S.; Drewes, R.; Cravo, E.; Lenzi, I.; Yin, C.; Kampa, B. M.; Churchland, A. K.

10.1101/2021.09.27.461599 — neuroscience — Posted on 2022-09-26

946 Scanning Single Molecule Localization Microscopy (scanSMLM) for super-resolution optical volume imaging

Basumatary, J.; Baro, N.; Joshi, P.; Mondal, P. P.

10.1101/2022.04.01.486682 — biophysics — Posted on 2022-09-26

947 LinAliFold and CentroidLinAliFold: Fast RNA consensus secondary structure prediction for aligned sequences using beam search methods

Fukunaga, T.; Hamada, M.

10.1101/2022.06.17.496559 — bioinformatics — Posted on 2022-09-26

948 Copy number variations shape the structural diversity of Arabidopsis metabolic gene clusters and are associated with the climatic gradient

Marszalek-Zenczak, M.; Satyr, A.; Wojciechowski, P.; Zenczak, M.; Sobieszczanska, P.; Brzezinski, K.; Iefimenko, T.; Figlerowicz, M.; Zmienko, A.

10.1101/2022.09.05.506152 — genomics — Posted on 2022-09-26

949 Pleiotropy drives repeatability in the genetic basis of adaptation

Battlay, P.; Yeaman, S.; Hodgins, K.

10.1101/2021.09.13.459985 — genetics — Posted on 2022-09-26

950 Divergent selection predating the Last Glacial Maximum mainly acted on macro-phenotypes in Norway spruce

Tiret, M.; Olsson, L.; Grahn, T.; Karlsson, B.; Milesi, P.; Lascoux, M.; Lundqvist, S.-O.; Garcia-Gil, M. R.

10.1101/2022.01.15.476468 — evolutionary biology — Posted on 2022-09-26

951 Disentangling the roles of inter and intraspecific variation on leaf trait distributions across the eastern United States

Marconi, S.; Weinstein, B. G.; Lichstein, J. W.; Bohlman, S. A.; Singh, A.; White, E. P.

10.1101/2021.04.01.438064 — ecology — Posted on 2022-09-26

952 Bat pluripotent stem cells reveal unique entanglement between host and viruses

Dejosez, M.; Marin, A.; Hughes, G.; Morales, A.; Godoy Parejo, C.; Gray, J.; Qin, Y.; Singh, A.; Xu, H.; Juste, J.; Ibanez, C.; White, K. M.; Rosales, R.; Francoeur, N.; Sebra, R.; Alcock, D.; Pastusiak, A.; Frost, S.; Hiller, M.; Young, R.; Teeling, E.; Garcia-Sastre, A.; Zwaka, T. P.

10.1101/2022.09.23.509261 — developmental biology — Posted on 2022-09-26

953 INSULIN-LIKE GROWTH FACTOR I REDUCES CORONARY ATHEROSCLEROSIS IN PIGS WITH FAMILIAL HYPERCHOLESTEROLEMIA

Sukhanov, S.; Higashi, Y.; Yoshida, T.; Danchuk, S.; Alfortish, M.; Goodchild, T.; Scarborough, A.; Sharp, T.; Jenkins, J. S.; Garcia, D.; Ivey, J.; Tharp, D. L.; Schumacher, J.; Rozenbaum, Z.; Kolls, J. K.; Bowles, D.; Lefer, D.; Delafontaine, P.

10.1101/2022.09.23.509213 — cell biology — Posted on 2022-09-26

954 Initial spindle positioning at the oocyte center protects against incorrect kinetochore-microtubule attachment and aneuploidy in mice

Kincade, J. N.; Hlavacek, A.; Akera, T.; Balboula, A. Z.

10.1101/2020.06.28.176594 — cell biology — Posted on 2022-09-26

955 Investigating microglia-neuron crosstalk by characterizing microglial contamination in human and mouse Patch-seq datasets

Arbabi, K.; Jiang, Y.; Howard, D.; Nigam, A.; Inoue, W.; Gonzalez-Burgos, G.; Felsky, D.; Tripathy, S. J.

10.1101/2022.09.07.507009 — neuroscience — Posted on 2022-09-26

956 Enhanced Mirror Neuron Network Activity and Effective Connectivity during Live Interaction Among Female Subjects

Hsu, C.-T.; Sato, W.; Kochiyama, T.; Nakai, R.; Asano, K.; Abe, N.; Yoshikawa, S.

10.1101/2022.04.22.489113 — neuroscience — Posted on 2022-09-26

957 Alignment-free Comparison of Metagenomics Sequences via Approximate String Matching

Chen, J.; Yang, L.; Li, L.; Goodison, S.; Sun, Y.

10.1101/2020.05.24.113852 — bioinformatics — Posted on 2022-09-26

958 High-dimensional association detection in large scale genomic data

Koch, H.; Keller, C. A.; Xiang, G.; Giardine, B.; Zhang, F.; Wang, Y.; Hardison, R. C.; Li, Q.

10.1101/2020.11.18.388504 — bioinformatics — Posted on 2022-09-26

959 Pleiotropy drives repeatability in the genetic basis of adaptation

Battlay, P.; Yeaman, S.; Hodgins, K.

10.1101/2021.09.13.459985 — genetics — Posted on 2022-09-26

960 Neural population dynamics of human working memory

Li, H.-H.; Curtis, C. E.

10.1101/2022.09.23.509245 — neuroscience — Posted on 2022-09-25

961 Morphological evolution of bird wings follows a mechanical sensitivity gradient determined by the aerodynamics of flapping flight

Rader, J. A.; Hedrick, T. L.

10.1101/2022.09.23.509279 — evolutionary biology — Posted on 2022-09-25

962 HNF1α transcriptional activation and repression maintain human islet α and β cell function

Qian, M. F.; Bevacqua, R. J.; Nguyen, V. M.; Liu, X.; Zhao, W.; Chang, C. A.; Gu, X.; Dai, X.-Q.; Macdonald, P. E.; Kim, S. K.

10.1101/2022.09.25.509394 — genetics — Posted on 2022-09-25

963 Separation of the effects of small intestinal microbiome-diet interactions on human gut hormone secretion

Di Rienzi, S. C.; Danhof, H. A.; Huerta, J.; Britton, R. A.

10.1101/2022.09.25.509333 — microbiology — Posted on 2022-09-25

964 In host evolution of Exophiala dermatitidis in cystic fibrosis lung micro-environment

Kurbessoian, T.; Murante, D.; Crocker, A. W.; Hogan, D. A.; Stajich, J. E.

10.1101/2022.09.23.509114 — microbiology — Posted on 2022-09-25

965 Top-down design of protein nanomaterials with reinforcement learning

Lutz, I. D.; Wang, S.; Norn, C.; Borst, A. J.; Zhao, Y. T.; Dosey, A.; Cao, L.; Li, Z.; Baek, M.; King, N. P.; Ruohola-Baker, H.; Baker, D.

10.1101/2022.09.25.509419 — synthetic biology — Posted on 2022-09-25

966 B lymphocytes in Treatment-Naive Pediatric Lupus Patients are Epigenetically Distinct from Healthy Children

Hui-Yuen, J.; Jiang, K.; Malkiel, S.; Eberhard, B. A.; Walters, H.; Diamond, B.; Jarvis, J. N.

10.1101/2022.09.23.509218 — genomics — Posted on 2022-09-25

967 The Effect of Repeat Length on Marcal1-Dependent Single-Strand Annealing in Drosophila

Dewey, E. B.; Holsclaw, J. K.; Saghaey, K.; Wittmer, M. E.; Sekelsky, J.

10.1101/2022.09.24.509346 — genetics — Posted on 2022-09-25

968 A targeted genetic modifier screen in Drosophila uncovers vulnerabilities in a genetically complex model of colon cancer

Datta, I.; Linkous, B. K.; Odum, T. Z.; Drew, C.; Taylor, A.; Vassel, T.; Bangi, E.

10.1101/2022.09.23.508936 — genetics — Posted on 2022-09-25

969 SAGA histone acetyltransferase module facilitates chromatin accessibility to SMC5/6

Mahrik, L.; Stefanovie, B.; Maresova, A.; Princova, J.; Kolesar, P.; Lelkes, E.; Helmlinger, D.; Prevorovsky, M.; Palecek, J. J.

10.1101/2022.09.24.508842 — genetics — Posted on 2022-09-25

970 RNA cytometry of single-cells using semi-permeable microcapsules

Leonaviciene, G.; Mazutis, L.

10.1101/2022.09.24.509327 — molecular biology — Posted on 2022-09-25

971 Single-nucleoid architecture reveals heterogeneous packaging of mitochondrial DNA

Isaac, R. S.; Tullius, T. W.; Hansen, K. G.; Dubocanin, D.; Couvillion, M.; Stergachis, A.; Churchman, L. S.

10.1101/2022.09.25.509398 — molecular biology — Posted on 2022-09-25

972 A novel, ssDNA Bidnavirus in the giant freshwater prawn Macrobrachium rosenbergii

Gangnonngiw, W.; Bunnontae, M.; Kayansamruaj, P.; Senapin, S.; Srisala, J.; Flegel, T. W.; Wongprasert, K.

10.1101/2022.09.25.509311 — microbiology — Posted on 2022-09-25

973 Digestive exophagy of Bacterial Biofilms by an Amoeba Predator is Mediated by Specific Biofilm Recognition

Zanditenas, E.; Trebicz-Geffen, M.; Dominguez-Garcia, L.; romero, d.; Kolodkin-Gal, I.; Ankri, S.

10.1101/2022.09.24.509356 — microbiology — Posted on 2022-09-25

974 A helminth mimic of TGF-β, TGM, enhances regenerative cutaneous wound healing and modulates immune cell recruitment and activation

Lothstein, K. E.; Chen, F.; Mishra, P.; Smyth, D. J.; Wu, W.; Lemenze, A.; Kumamoto, Y.; Maizels, R. M.; Gause, W. C.

10.1101/2022.09.24.509317 — immunology — Posted on 2022-09-25

975 Acquired secondary HER2 mutations enhance HER2/MAPK signaling and promote resistance to HER2 kinase inhibition in HER2-mutant breast cancer

Marin, A.; Mamun, A. A.; Akamatsu, H.; Ye, D.; Sudhan, d. R.; Brown, B. P.; Eli, L.; Marcelain, K.; Meiler, J.; Arteaga, C. L.; Hanker, A. B.

10.1101/2022.09.23.509246 — cancer biology — Posted on 2022-09-25

976 Regulation of the Phage Lambda Viral Packaging Motor's Grip and DNA End-clamp Mechanism

Rawson, B.; Yang, Q.; Catalano, C. E.; Smith, D. E.

10.1101/2022.09.24.509349 — biophysics — Posted on 2022-09-25

977 Benchmark data and software for assessing genome-wide CRISPR-Cas9 screening pipelines

Iannuzzi, R.; Manipur, I.; Pacini, C.; Behan, F. M.; Guarracino, M. R.; Garnett, M. J.; Savino, A.; Iorio, F.

10.1101/2022.09.23.509258 — bioinformatics — Posted on 2022-09-25

978 Nicotinamide-N-methyltransferase is essential for SAM and 1-methylnicotinamide homeostasis in the AML12 hepatocyte cell line

Yoda, M.; Mizuno, R.; Yoshihiro, I.; Takahashi, M.; Bamba, T.; Kawaoka, S.

10.1101/2022.09.25.509348 — biochemistry — Posted on 2022-09-25

979 The WW domain of IQGAP1 binds directly to the p110α catalytic subunit of PI 3-kinase

Bardwell, A. J.; Andrade-Ludena, M. D.; Yoneda, K. C.; Nguyen, O. T.; Fruman, D. A.; Bardwell, L.

10.1101/2022.09.24.509339 — biochemistry — Posted on 2022-09-25

980 Stitched peptides as potential cell permeable inhibitors of oncogenic DAXX protein

Jelinska, C.; Kannan, S.; Winnerdy, F. R.; Frosi, Y.; Ramlan, S. R.; Lakshminarayanan, R.; Brown, C. J.; Phan, A.-T.; Rhodes, D.; Verma, C. S.

10.1101/2022.09.25.508451 — biochemistry — Posted on 2022-09-25

981 Natural and human-mediated drivers of microevolution in Neotropical palms: a historical genomics approach

Brousseau, L.; Santoni, S.; Weber, A.; Odonne, G.

10.1101/2022.04.08.486529 — evolutionary biology — Posted on 2022-09-25

982 Gene regulatory changes underlie developmental plasticity in respiration and aerobic performance in highland deer mice

Schweizer, R. M.; Ivy, C. M.; Natarajan, C.; Scott, G. R.; Storz, J. F.; Cheviron, Z. A.

10.1101/2022.09.24.509328 — molecular biology — Posted on 2022-09-25

983 RNA recoding in cephalopods tailors microtubule motor protein function

Rangan, K. J.; Reck-Peterson, S. L.

10.1101/2022.09.25.509396 — molecular biology — Posted on 2022-09-25

984 Ceg1 depletion reveals mechanisms governing degradation of non-capped RNAs

Zanin, O.; Hebenstreit, D.; Grzechnik, P.

10.1101/2022.09.24.509330 — molecular biology — Posted on 2022-09-25

985 Mechanical stimuli activate gene expression via a cell envelope stress sensing pathway

Harper, C. E.; Zhang, W.; Shin, J.-H.; van Wijngaarden, E.; Chou, E.; Lee, J.; Wang, Z.; Doerr, T.; Chen, P.; Hernandez, C. J.

10.1101/2022.09.25.509347 — microbiology — Posted on 2022-09-25

986 Cryo-EM structure of the Agrobacterium tumefaciens type IV secretion system-associated T-pilus reveals stoichiometric protein-phospholipid assembly

Kreida, S.; Narita, A.; Johnson, M. D.; Tocheva, E. I.; Das, A.; Ghosal, D.; Jensen, G. J.

10.1101/2022.09.25.509369 — microbiology — Posted on 2022-09-25

987 Predictive neural representations of naturalistic dynamic input

de Vries, I. E. J.; Wurm, M. F.

10.1101/2022.09.02.506366 — neuroscience — Posted on 2022-09-25

988 PICLN modulates alternative splicing and ensures adaptation to light and temperature changes in plants

Mateos, J. L.; Sanchez, S. E.; Legris, M.; Esteve-Bruna, D.; Torchio, J. C.; Petrillo, E.; Goretti, D.; Blanco-Tourinan, N.; Seymour, D. K.; Schmid, M.; Weigel, D.; Alabadi, D.; Yanovsky, M. J.

10.1101/2022.06.14.496170 — plant biology — Posted on 2022-09-25

989 A unified framework of realistic in silico data generation and statistical model inference for single-cell and spatial omics

Song, D.; Wang, Q.; Yan, G.; Liu, T.; Li, J. J.

10.1101/2022.09.20.508796 — bioinformatics — Posted on 2022-09-25

990 Reciprocal Best Structure Hits: Using AlphaFold models to discover distant homologues

Monzon, V. A.; Paysan-Lafosse, T.; Wood, V.; Bateman, A.

10.1101/2022.07.04.498216 — bioinformatics — Posted on 2022-09-25

991 Tandemly repeated genes promote RNAi-mediated heterochromatin formation via an anti-silencing factor Epe1 in fission yeast

Asanuma, T.; Inagaki, S.; Kakutani, T.; Aburatani, H.; Murakami, Y.

10.1101/2022.07.04.498379 — biochemistry — Posted on 2022-09-25

992 FACS-assisted single-cell lipidome analysis of phosphatidylcholines and sphingomyelins

Hancock, S. E.; Ding, E.; Johansson Beves, E.; Mitchell, T. W.; Turner, N.

10.1101/2022.02.15.479799 — biochemistry — Posted on 2022-09-25

993 Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Nguyen, A.; Lugarini, F.; David, C.; Hosani, P.; Knotkova, B.; Patel, A.; Parfentev, I.; Friedrich, A.; Urlaub, H.; Meinecke, M.; Stork, B.; Faesen, A.

10.1101/2022.09.21.508836 — biochemistry — Posted on 2022-09-25

994 Genome-wide binding of Multiple ankyrin repeats single KH domain reveals its role in maintenance of gene activation by trithorax group proteins in Drosophila

Shaukat, A.; Khan, M. H. F.; Akhtar, J.; Bakhtiari, M. H.; Haseeb, M. A.; Mazhar, K.; Umer, Z.; Tariq, M.

10.1101/2022.03.15.484481 — genomics — Posted on 2022-09-25

995 A truncated form of the p27 CDK inhibitor translated from pre-mRNA causes G2-phase arrest

Kaida, D.; Satoh, T.; Ishida, K.; Yoshimoto, R.; Komori, K.

10.1101/2022.01.12.476115 — molecular biology — Posted on 2022-09-25

996 Task-related temporal fluctuations in auditory attention generate neural signatures that change with age

Herrmann, B.; Maess, B.; Henry, M. J.; Obleser, J.; Johnsrude, I. S.

10.1101/2022.04.12.487991 — neuroscience — Posted on 2022-09-25

997 Decision heuristics in contexts exploiting intrinsic skill

Dundon, N. M.; Colas, J. T.; Garrett, N.; Babenko, V.; Rizor, E.; Yang, D.; MacNamara, M.; Petzold, L.; Grafton, S. T.

10.1101/2022.04.01.486746 — neuroscience — Posted on 2022-09-25

998 A Murine Model of Abductor Insufficiency Accelerates the Development of Hip Osteoarthritis

Geary, M. B.; Orner, C. A.; Shammas, H.; Reuter, J. M.; Loiselle, A. E.; Giordano, B. D.; Wu, C.-L.

10.1101/2022.05.22.492940 — pathology — Posted on 2022-09-25

999 ADRA2B and HTR1A: An updated study of the biogenic amine receptors reveals novel conserved motifs which play key role in Mental Disorders.

Papageorgiou, L.; Christou, E.; Louka, E.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Chrousos, G. P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508280 — bioinformatics — Posted on 2022-09-25

1000 Genetic, clinical underpinnings of subtle early brain change along Alzheimer's dimensions

Wen, J.; Yang, Z.; Nasrallah, I.; Cui, Y.; Erus, G.; Srinivasan, D.; Abdulkadir, A.; Mamourian, E.; Hwang, G.; Singh, A.; Bergman, M.; Bao, J.; Varol, E.; Zhou, Z.; Boquet-Pujadas, A.; Chen, J.; Toga, A. W.; Saykin, A. J.; Hohman, T.; Thompson, P.; Villeneuve, S.; Gollub, R.; Sotiras, A.; Wittfeld, K.; Grabe, H.; Tosun, D.; Bilgel, M.; An, Y.; Marcus, D.; LaMontagne, P. J.; Heckbert, S.; Austin, T.; Launer, L.; Espeland, M.; Masters, C.; Maruff, P.; Fripp, J.; Johnson, S. C.; Morris, J.; Albert, M.; Bryan, R. N.; Resnick, S. M.; Ferrucci, L.; Fan, Y.; Mohamad, H.; Wolk, D.; Shen, L.; Shou, H.;

10.1101/2022.09.16.508329 — bioengineering — Posted on 2022-09-25

1001 Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids

Costa, B.; Li Calzi, M.; Castellano, M.; Blanco, V.; Cuevasanta, E.; Litvan, I.; Ivanov, P.; Witwer, K.; Cayota, A.; Tosar, J. P.

10.1101/2022.08.31.506125 — molecular biology — Posted on 2022-09-25

1002 Piperacillin-Tazobactam Resistance Mechanisms in Escherichia coli and Identification of a CTX-M-255 β-Lactamase Selectively Conferring Resistance to Penicillin/β-Lactamase Inhibitor Combinations

Andreasen, M. R.; Hartung Hansen, K.; Pedersen, M. S.; Mollerup, S.; Jelsbak, L.; Schonning, K.

10.1101/2022.09.21.508968 — microbiology — Posted on 2022-09-25

1003 Geobacter sulfurreducens' unique metabolism results in cells with a high iron and lipid content

Howley, E. T.; Ki, D.; Krajmalnik-Brown, R.; Torres, C. I.

10.1101/2022.07.29.502083 — microbiology — Posted on 2022-09-25

1004 Beet curly top Iran virus Rep and V2 gene work as suppressors of post-transcriptional gene silencing through separate mechanisms

Ebrahimi, S.; Eini, O.; Bassler, A.; Yildirim, Z.; Wassenegger, M.; Krczal, G.; Uslu, V. V.

10.1101/2022.08.25.505242 — plant biology — Posted on 2022-09-25

1005 Super-resolution imaging reveals dynamic reticular cytoophidia

Fang, Y.; Li, Y.-L.; Li, X.-M.; Liu, J.-L.

10.1101/2022.08.29.505636 — biophysics — Posted on 2022-09-25

1006 Cross-modal Graph Contrastive Learning with Cellular Images

Zheng, S.; Rao, J.; Zhang, J.; Cohen, E.; Li, C.; Yang, Y.

10.1101/2022.06.05.494905 — bioinformatics — Posted on 2022-09-25

1007 Visual processing and collective motion-related decision-making in desert locusts

Bleichman, I.; Yadav, P.; Ayali, A.

10.1101/2022.09.19.508462 — animal behavior and cognition — Posted on 2022-09-25

1008 YAP/TAZ mediate TGFβ2-induced Schlemm's canal cell dysfunction

Li, H.; Singh, A.; Perkumas, K. M.; Stamer, W. D.; Ganapathy, P. S.; Herberg, S.

10.1101/2022.06.06.494681 — cell biology — Posted on 2022-09-25

1009 ErbB Signalling is a Potential Therapeutic Target for Vascular Lesions with Fibrous Component

Ilmonen, H.; Jauhiainen, S.; Vuola, P.; Rasinkangas, H.; Pulkkinen, H. H.; Keränen, S.; Kiema, M.; Liikkanen, J. J.; Laham-Karam, N.; Laidinen, S.; Aavik, E.; Lappalainen, K.; Lohi, J.; Aronniemi, J.; Örd, T.; Kaikkonen, M. U.; Salminen, P.; Tukiainen, E.; Ylä-Herttuala, S.; Laakkonen, J. P.

10.1101/2022.09.23.509204 — cell biology — Posted on 2022-09-25

1010 Microbiome and resistome dynamics along a sewage-effluent-reservoir continuum underline the role of natural attenuation in effluent receiving reservoirs

Cytryn, E.; Leao, I.; Khalifa, L.; Merlin, C.; Gallois, N.; Vaz-Moreira, I.; Klümper, U.; Youdkes, D.; Palmony, S.; Dagai, L.; Berendonk, T. U.; Manaia, C.

10.1101/2022.09.21.508967 — microbiology — Posted on 2022-09-25

1011 Discovery of homogentisic acid as a precursor in trimethoprim metabolism and natural product biosynthesis

Mcavoy, A. C.; Threatt, P. H.; Kapcia, J.; Garg, N.

10.1101/2022.09.22.509022 — microbiology — Posted on 2022-09-25

1012 Programmed cell death-1 receptor mediated regulation of Tbet+ NK1.1- Innate Lymphoid Cells within the Tumor Microenvironment

Lim, M.; Lai, C.; Mallett, G.; McDonald, D.; Hulme, G.; Laba, S.; Shapanis, A.; Payne, M.; Patterson, W.; Alexander, M.; Coxhead, J.; Filby, A.; Plummer, R.; Lovat, P.; Sciume, G.; Healy, E.; Amarnath, S.

10.1101/2022.09.21.507469 — immunology — Posted on 2022-09-25

1013 Neural correlates of an illusive sense of agency caused by virtual reality

Cai, Y.; Yang, H.; Xiong, Z.; Kühn, S.; Bi, Y.; Wei, K.

10.1101/2022.09.21.508963 — neuroscience — Posted on 2022-09-25

1014 Glucose intolerance in aging is mediated by the Gpcpd1-GPC metabolic axis

Cikes, D.; Leutner, M.; Cronin, S. J. - F.; Novatchkova, M.; Pfleger, L.; Klepochova, R.; Rullman, E.; Gustafsson, T.; Hagelkrueys, A.; Knauf, C.; Moro, C.; Krebs, M.; Kautzky-Willer, A.; Krssak, M.; Orthofer, M.; Penninger, J. M.; Lair, B.; Lac, M.; Bergoglio, C.; Tavernier, G.; Bourlier, V.; Durnberger, G.; Roitinger, E.

10.1101/2021.10.26.465828 — physiology — Posted on 2022-09-25

1015 The joint associations of physical activity, sedentary time, and sleep on V{dot}O2max in trained and untrained children and adolescents: A novel five-part compositional analysis

Runacres, A.; MacKintosh, K. A.; Chastin, S.; McNarry, M. A.

10.1101/2022.09.21.508871 — physiology — Posted on 2022-09-25

1016 Cryo-EM structure of a eukaryotic zinc transporter at a low pH suggests its Zn2+-releasing mechanism

Zhang, S.; Fu, C.; Luo, Y.; Xie, Q.; Xu, T.; Sun, Z.; Su, Z.; Zhou, X.

10.1101/2022.06.29.497979 — biochemistry — Posted on 2022-09-25

1017 Transcriptional response of circadian clock genes to an 'artificial light at night' pulse in the cricket Gryllus bimaculatus

Levy, K.; Fishman, B.; Barnea, A.; Ayali, A.; Tauber, E.

10.1101/2022.08.31.505991 — animal behavior and cognition — Posted on 2022-09-25

1018 Massive Horizontal Gene Transfer in Amphioxus Illuminates the Early Evolution of Deuterostomes

Xiong, Q.; Yang, K. Y.; Zeng, X.; Wang, M.; Ng, P. K.-S.; Zhou, J.-W.; Ng, J. K.-W.; Law, C. T.-Y.; Du, Q.; Xu, K.; Falkenberg, L. J.; Mao, B.; Chen, J.-Y.; Tsui, S. K.-W.

10.1101/2022.05.18.492404 — evolutionary biology — Posted on 2022-09-25

1019 Parallel evolution of amphioxus and vertebrate small-scale gene duplications

Braso-Vives, M.; Marletaz, F.; Echchiki, A.; Mantica, F.; Acemel, R. D.; Gomez-Skarmeta, J. L.; Hartasanchez, D. A.; Targa, L. L.; Pontarotti, P.; Tena, J. J.; Maeso, I.; Escriva, H.; Irimia, M.; Robinson-Rechavi, M.

10.1101/2022.01.18.476203 — evolutionary biology — Posted on 2022-09-25

1020 The non-random structure of multi-trophic ecological interactions maximizes species coexistence

Garcia-Callejas, D.; Godoy, O.; Buche, L.; Hurtado, M.; B. Lanuza, J.; Allen-Perkins, A.; Bartomeus, I.

10.1101/2021.11.29.470335 — ecology — Posted on 2022-09-25

1021 CD90 is not constitutively expressed in functional innate lymphoid cells

Schroeder, J.-H.; Beattie, G.; Lo, J. W.; Zabinski, T.; Jenner, R.; Powell, N.; Neves, J. F.; Lord, G. M.

10.1101/2021.12.11.472210 — immunology — Posted on 2022-09-25

1022 Daily oscillation of the excitation/inhibition ratio is disrupted in two mouse models of autism

Bridi, M.; Luo, N.; Kim, G.; O'Ferrall, C.; Oatel, R.; Bertrand, S.; Kannan, S.; Kirkwood, A.

10.1101/2021.07.05.451213 — neuroscience — Posted on 2022-09-25

1023 Spontaneous neurotransmission at evocable synapses predicts their responsiveness to action potentials

Grasskamp, A. T.; Jusyte, M.; McCarthy, A. W.; Goetz, T. W. B.; Ditlevsen, S.; Walter, A. M.

10.1101/2020.08.28.271742 — neuroscience — Posted on 2022-09-25

1024 Auditory word comprehension is less incremental in isolated words

Gaston, P.; Brodbeck, C.; Phillips, C.; Lau, E.

10.1101/2021.09.09.459631 — neuroscience — Posted on 2022-09-25

1025 Sustained responses and neural synchronization to amplitude and frequency modulation in sound change with age

Herrmann, B.; Maess, B.; Johnsrude, I. S.

10.1101/2022.04.28.489911 — neuroscience — Posted on 2022-09-25

1026 Feature detecting columnar neurons mediate object tracking saccades in Drosophila

Frighetto, G.; Frye, M. A.

10.1101/2022.09.21.508959 — neuroscience — Posted on 2022-09-25

1027 Decoding the IGF1 Signaling Gene Regulatory Network Behind Alveologenesis from A Mouse Model of Bronchopulmonary Dysplasia

Gao, F.; Li, C.; Smith, S.; Peinado, N.; Kohbodi, G.; Tran, E.; Loh, E.; Li, W.; Borok, Z.; Minoo, P.

10.1101/2022.01.24.477613 — developmental biology — Posted on 2022-09-25

1028 CRISPR-Cas Controls Cryptic Prophages

Song, S.; Semenova, E.; Severinov, K.; Garcia, L. F.; Benedik, M. J.; Maeda, T.; Wood, T. K.

10.1101/2021.07.28.454074 — molecular biology — Posted on 2022-09-25

1029 Parametric control of flexible timing through low-dimensional neural manifolds

Beiran, M.; Meirhaeghe, N.; Sohn, H.; Jazayeri, M.; Ostojic, S.

10.1101/2021.11.08.467806 — neuroscience — Posted on 2022-09-25

1030 Allosteric Inhibition of the T Cell Receptor by a Designed Membrane Ligand

Ye, Y.; Morita, S.; Wilhelm, K.; Groves, J. T.; Barrera, F. N.

10.1101/2022.08.19.503518 — biophysics — Posted on 2022-09-25

1031 Ultraliser: a framework for creating multiscale, high-fidelity and geometrically realistic 3D models for in silico neuroscience

Abdellah, M.; Garcia Cantero, J. J.; Roman Guerrero, N.; Foni, A.; Coggan, J. S.; Cali, C.; Agus, M.; Zisis, E.; Keller, D.; Hadwiger, M.; Magistretti, P.; Markram, H.; Schürmann, F.

10.1101/2022.07.27.501675 — bioinformatics — Posted on 2022-09-25

1032 ICAT: A Novel Algorithm to Robustly Identify Cell States Following Perturbations in Single Cell Transcriptomes

Hawkins, D. Y.; Zuch, D. T.; Huth, J.; Rodriguez-Sastre, N. C.; McCutcheon, K. R.; Glick, A.; Lion, A. T.; Thomas, C. F.; Descoteaux, A.; Johnson, W. E.; Bradham, C.

10.1101/2022.05.26.493603 — bioinformatics — Posted on 2022-09-25

1033 HAYSTAC: A Bayesian framework for robust and rapid species identification in high-throughput sequencing data

Dimopoulos, E. A.; Carmagnini, A.; Velsko, I. M.; Warinner, C.; Larson, G.; Frantz, L. A. F.; Irving-Pease, E. K.

10.1101/2020.12.16.419085 — bioinformatics — Posted on 2022-09-25

1034 Deep mutational scanning and massively parallel kinetics of plasminogen activator inhibitor-1 functional stability

Haynes, L. M.; Huttinger, Z. M.; Yee, A.; Kretz, C. A.; Siemieniak, D. R.; Lawrence, D. A.; Ginsburg, D.

10.1101/2022.07.19.500671 — biochemistry — Posted on 2022-09-25

1035 Foxes engineer hotspots of wildlife activity on the nutrient-limited Arctic tundra

Zhao, S.-T.; Johnson-Bice, S. M.; Roth, J. D.

10.1101/2021.03.19.436172 — ecology — Posted on 2022-09-25

1036 Feasibility of enhancing carbon sequestration andstock capacity in temperate and boreal European forests via changes to management regimes

Dalmonech, D.; Marano, G.; Amthor, J.; Cescatti, A.; Lindner, M.; Trotta, C.; Collalti, A.

10.1101/2022.02.10.479900 — ecology — Posted on 2022-09-25

1037 Natural and pathological aging distinctively impact the vomeronasal system and social behavior

Portales, A.; Chamero, P.; Jurado, S.

10.1101/2022.08.31.505522 — neuroscience — Posted on 2022-09-25

1038 Longitudinal single-cell chemical imaging of engineered strains reveals heterogeneity in fatty acid production

Tague, N.; Lin, H.; Lugagne, J.-B.; O'Connor, O. M.; Burman, D.; Wong, W.; Cheng, J.-X.; Dunlop, M.

10.1101/2021.07.26.453865 — synthetic biology — Posted on 2022-09-25

1039 KDM4A promotes NEPC progression through regulation of MYC expression

Mak, C. S. L.; Zhu, M.; Liang, X.; Wang, F.; Hoang, A. G.; Song, X.; Shepherd, P.; Liang, D.; Park, J.; Zhang, M.; Metzger, E.; Schule, R.; Jain, A. K.; Foster, B. A.; Lee, M. G.; Corn, P.; Logothetis, C. J.; Aparicio, A.; Navone, N.; Troncoso, P.; Zhang, J.; Lin, S.-H.; Wang, G.

10.1101/2022.05.14.491739 — cancer biology — Posted on 2022-09-25

1040 binny: an automated binning algorithm to recover high-quality genomes from complex metagenomic datasets

Hickl, O.; Queiros, P.; Wilmes, P.; May, P.; Heintz-Buschart, A.

10.1101/2021.12.22.473795 — bioinformatics — Posted on 2022-09-25

1041 Development of Machine Learning Model for Pan-cancer Subgroup Identification using Multi-omics Data

Khadirnaikar, S. R.; Shukla, S.; Prasanna, S. R. M.

10.1101/2022.09.15.507989 — bioinformatics — Posted on 2022-09-25

1042 A self-adjusting, progressive shock strength procedure to investigate resistance to punishment: characterization in male and female rats

Desmercieres, S.; Lardeux, V.; Longueville, J.-E.; Hanna, M.; Panlilio, L. V.; Thiriet, N.; Solinas, M.

10.1101/2022.03.12.481595 — animal behavior and cognition — Posted on 2022-09-25

1043 Fitness costs and benefits in response to artificial artesunate selection in Plasmodium

Villa, M.; Berthomieu, A.; Rivero, A.

10.1101/2022.01.28.478164 — evolutionary biology — Posted on 2022-09-25

1044 The evolution of manipulative cheating

Liu, M.; West, S. A.; Wild, G.

10.1101/2022.05.26.493573 — evolutionary biology — Posted on 2022-09-25

1045 Reprogramming of Iron Metabolism Confers Ferroptosis Resistance in ECM-Detached Cells

He, J.; Abikoye, A. M.; McLaughlin, B. P.; Middleton, R. S.; Sheldon, R.; Jones, R. G.; Schafer, Z. T.

10.1101/2022.09.23.509253 — cell biology — Posted on 2022-09-25

1046 An approach towards identifying the site of interaction between the Streptomyces phage PhiC31 protein Gp3 and the coiled-coil domain of its serine integrase

Halablab, M.-L.-K.

10.1101/2022.09.24.509315 — synthetic biology — Posted on 2022-09-25

1047 Reduced mitochondrial transcription sensitizes acute myeloid leukemia cells to BCL-2 inhibition

Arabanian, L. S.; Adamsson, J.; Unger, A.; Di Lucrezia, R.; Bergbrede, T.; Ashouri, A.; Larsson, E.; Nussbaumer, P.; Klebl, B. M.; Palmqvist, L.; Gustafsson, C. M.

10.1101/2022.09.23.509145 — cancer biology — Posted on 2022-09-25

1048 Moderate activity of RNA chaperone maximizes the yield of self-spliced pre-RNA in vivo

Song, Y.; Thirumalai, D.; Hyeon, C.

10.1101/2022.09.20.508801 — biophysics — Posted on 2022-09-24

1049 Effects of microtubule length and crowding on active microtubule network organization

chew, w. x.; Henkin, G.; Nedelec, F.; Surrey, T.

10.1101/2022.09.23.509184 — biophysics — Posted on 2022-09-25

1050 Enhancing Sox/Oct cooperativity induces higher-grade developmental reset

MacCarthy, C. M.; Malik, V.; Wu, G.; Velychko, T.; Keshet, G.; Jauch, R.; Cojocaru, V.; Scholer, H.; Velychko, S.

10.1101/2022.09.23.509242 — developmental biology — Posted on 2022-09-25

1051 Ribosomal RNA 2'-O-methylation dynamics impact cell fate decisions

Hafner, S. J.; Jansson, M. D.; Altinel, K.; Kraushar, M.; Andersen, K. L.; Caldwell Abay-Norgaard, Z.; Fontenas, M.; Sorensen, D.; Gay, D. M.; Arendrup, F. S.; Tehler, D.; Krogh, N.; Nielsen, H.; Kirkeby, A.; Lund, A. H.

10.1101/2022.09.24.509301 — developmental biology — Posted on 2022-09-25

1052 Reevaluation of Piezo1 as a gut RNA sensor

Nickolls, A. R.; O'Brien, G. S.; Shnayder, S.; Zhang, Y.; Nagel, M.; Patapoutian, A.; Chesler, A. T.

10.1101/2022.09.23.509216 — cell biology — Posted on 2022-09-24

1053 A spatial atlas of Wnt and Frizzled receptor expression in adult mouse liver

Gayden, J.; Hu, S.; Joseph, P. N.; Delgado, E.; Liu, S.; Bell, A.; Puig, S.; Monga, S. P.; Freyberg, Z.

10.1101/2022.09.23.509269 — cell biology — Posted on 2022-09-24

1054 The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia

Shinde, S. R.; Mick, D. U.; Aoki, E.; Nachury, M. V.

10.1101/2022.09.23.509287 — cell biology — Posted on 2022-09-25

1055 Transcriptomics data integration for context-specific modeling of Atlantic salmon metabolism: functional evaluation of methods based on metabolic tasks

Molversmyr, H.; Oyas, O.; Rotnes, F.; Vik, J. O.

10.1101/2022.09.23.509266 — systems biology — Posted on 2022-09-24

1056 Continuous directed evolution of a feedback-resistant Arabidopsis arogenate dehydratase in plantized E. coli

Leong, B. J.; Hanson, A. D.

10.1101/2022.09.24.509247 — synthetic biology — Posted on 2022-09-24

1057 Chemical bonds in collagen rupture selectivelyunder tensile stress

Rowe, J.; Roeder, K.

10.1101/2022.09.23.509192 — molecular biology — Posted on 2022-09-24

1058 Olfactory neuronal cells: biopsied surrogates for neurons in the brain

Yang, K.; Ishizuka, K.; Narita, Z.; Lema, Y. Y.; Zhang, S.; Duan, J.; Younes, L.; Geman, D.; Lane, A. P.; Sawa, A.

10.1101/2022.09.23.509290 — molecular biology — Posted on 2022-09-24

1059 Decoding a cryptic mechanism of metronidazole resistance among globally disseminated fluoroquinolone-resistant Clostridioides difficile

10.1101/2022.09.23.509282 — microbiology — Posted on 2022-09-24

1060 Identification of 2-amino benzothiazoles with bactericidal activity against Mycobacterium tuberculosis

Bonnett, S. A.; Jee, J.-A.; Chettiar, S.; Ovechkina, Y.; Korkegian, A.; Greve, E.; Odingo, J.; Parish, T.

10.1101/2022.09.23.509298 — microbiology — Posted on 2022-09-24

1061 Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes

Jamwal, A.; Constantin, C.; Henrich, S.; Bildl, W.; Fakler, B.; Draper, S.; Schulte, U.; Higgins, M. K.

10.1101/2022.09.23.509221 — microbiology — Posted on 2022-09-24

1062 Tunable dynamics in a multi-straintranscriptional pulse generator

Zong, D. M.; Sadeghpour, M.; Molinari, S.; Alnahhas, R. N.; Hirning, A. J.; Giannitsis, C.; Ott, W.; Josic, K.; Bennett, M. R.

10.1101/2022.09.23.509237 — synthetic biology — Posted on 2022-09-24

1063 R2Dtool: Positional interpretation of RNA-centric information in the context of transcriptomic and genomic features

Sethi, A. J.; Acera Mateos, P.; Shirokikh, N. E.; Eyras, E.

10.1101/2022.09.23.509222 — bioinformatics — Posted on 2022-09-24

1064 Metallothionein-3 attenuates the effect of Cu2+ ions on actin filaments

Lakha, R.; Hachicho, C.; Mehlenbacher, M. R.; Wilcox, D. E.; Austin, R. N.; Vizcarra, C. L.

10.1101/2022.09.23.509211 — biochemistry — Posted on 2022-09-24

1065 The role of the γ subunit in the photosystem of the lowest-energy phototrophs

Namoon, D.; Rudling, N. M.; Canniffe, D. P.

10.1101/2022.09.24.509313 — biochemistry — Posted on 2022-09-24

1066 Genome-scale mapping of DNA damage suppressors identifies GNB1L as essential for ATM and ATR biogenesis

Zhao, Y.; Tabet, D.; Rubio Contreras, D.; Kousholt, A. N.; Weile, J.; Melo, H.; Hoeg, L.; Cote, A. G.; Lin, Z.-Y.; Setiaputra, D.; Jonkers, J.; Gingras, A.-C.; Gomez Herreros, F.; Roth, F. P.; Durocher, D.

10.1101/2022.09.23.508845 — molecular biology — Posted on 2022-09-24

1067 Novel Biosensor Identifies Ruxolitinib as a Potent and Cardioprotective CaMKII Inhibitor

Reyes Gaido, O. E.; Granger, J. M.; Nkashama, L. J.; Lin, B. L.; Long, A.; Mesubi, O. O.; Schole, K. L.; Terrillion, C. E.; Liu, J. O.; Luczak, E. D.; Anderson, M. E.

10.1101/2022.09.24.509320 — molecular biology — Posted on 2022-09-24

1068 Molecular characters and phylogenetic analysis of Clostridium perfringens from different regions in China, from 2013 to 2021

Zhong, J.; Zheng, H.; Wang, Y.; Bai, L.; Du, X.; Wu, Y.; Lu, J.

10.1101/2022.09.23.509295 — molecular biology — Posted on 2022-09-24

1069 Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability

Xie, C. T. Y.; Pastore, S.; Vincent, J. B.; Frankland, P.; Hamel, P.

10.1101/2022.09.23.509248 — molecular biology — Posted on 2022-09-24

1070 Assembly and architecture of the type III secretion sorting platform

Soto, J. E.; Galan, J. E.; Lara-Tejero, M.

10.1101/2022.09.23.509200 — microbiology — Posted on 2022-09-24

1071 Reduced ribosome activity influences the non-uniform evolution of 16S rRNA hypervariable regions

Moore, S. D.; Bose, N.

10.1101/2022.09.23.509299 — microbiology — Posted on 2022-09-24

1072 Astrocytic synapse elimination controls ocular dominance plasticity

Lee, J.-H.; Kim, J.; Kim, M.; Shin, C.-H.; Chung, W.-S.

10.1101/2022.09.23.509193 — neuroscience — Posted on 2022-09-24

1073 Microprobe-XRF assessment of nutrient distribution in soybean, cowpea, and kidney bean seeds: a Fabaceae family case study

Montanha, G. S.; Zachi Romeu, S. L.; Marques, J. P. R.; Rohr, L. A.; de Almeida, E.; dos Reis, A. R.; Linhares, F. S.; Sabatini, S.; Pereira de Carvalho, H. W.

10.1101/2022.09.23.509231 — biochemistry — Posted on 2022-09-24

1074 GTP as an enzymatic synchronizer

Guo, C.-J.; Zhou, X.; Liu, J.-L.

10.1101/2022.09.24.509316 — biochemistry — Posted on 2022-09-24

1075 Compensatory Relationship between Low Complexity Regions and Gene Paralogy in the Evolution of Prokaryotes

Persi, E.; Wolf, Y. I.; karamycheva, S.; Makarova, K.; Koonin, E. V.

10.1101/2022.09.23.509281 — evolutionary biology — Posted on 2022-09-24

1076 Estradiol (E2) concentration shapes the chromatin binding landscape of the estrogen receptor

Han, A. L.; Vinod Paul, K.; Rao, S.; Brechbuhl, H. M.; Sartorius, C. A.; Ramachandran, S.; Kabos, P.

10.1101/2022.09.23.509212 — molecular biology — Posted on 2022-09-24

1077 A genetically-encoded three-colour stress biosensor reveals multimodal response at single cell level and spatiotemporal dynamics of biofilms

Zoheir, A. E.; Sobol, M. S.; Ordonez-Rueda, D.; Kaster, A.-K.; Niemeyer, C. M.; Rabe, K. S.

10.1101/2022.09.23.509207 — microbiology — Posted on 2022-09-24

1078 Global mosquito virome profiling and mosquito spatial diffusion pathways revealed by marker-viruses

Zhao, L.; Yu, P.; Shi, C.; Jia, L.; Evans, A.; Wang, X.; Wu, Q.; Xiong, G.; Ming, Z.; Salazar, F.; Agwanda, B.; Bente, D.; Wang, F.; Liu, D.; Yuan, Z.; Xia, H.

10.1101/2022.09.24.509300 — microbiology — Posted on 2022-09-24

1079 Compounds derived from N,N-dimethyldithiocarbamate are effective copper-dependent antimicrobials against Streptococcus pneumoniae

Johnson, M. D. L.; Menghani, S. V.; Sanchez-Rosario, Y.; Pok, C.; Liu, R.; Gao, F.; O'Brien, H. L.; Neubert, M.; Ochoa, K.; Hellinger, R. D.; Wang, W.

10.1101/2022.09.23.509297 — microbiology — Posted on 2022-09-24

1080 Multisensory inputs control the regulation of time investment for mating by sexual experience in male Drosophila melanogaster

Kim, W. J.; Lee, S. G.; Kang, C.; Saad, B.; Nguyen, K.-N. H.; Guerra-Phalen, A.; Bui, D.; Abbas, A.-H.; Trinh, B.; Malik, A.; Zeghal, M.; Auge, A.-C.; Islam, M. E.; Wong, K.; Stern, T.; Lebedev, E.; Sun, D.; Miao, H.; Wu, Z.; Sherratt, T. N.

10.1101/2022.09.23.509131 — neuroscience — Posted on 2022-09-24

1081 Cell-type specific deletions of Neuroligin 2 reveal a vital role of synaptic excitation-inhibition balance

Longley, C. M.; Xu, X.; Messier, J. E.; Cai, Z.-L.; Park, J. W.; Chen, H.; Reznik, D. L.; Jadi, M. P.; Xue, M.

10.1101/2022.09.23.509267 — neuroscience — Posted on 2022-09-24

1082 Release of the pre-assembled naRNA-LL37 composite DAMP re-defines neutrophil extracellular traps (NETs) as intentional DAMP webs

Bork, F.; Greve, C. L.; Youn, C.; Chen, S.; Wang, Y.; Nasri, M.; Focken, J.; Scheurer, J.; Engels, P.; Dubbelaar, M.; Hipp, K.; Schittek, B.; Bugl, S.; Loeffler, M. W.; Skokowa, J.; Archer, N. K.; Weber, A. N.

10.1101/2022.07.26.499571 — immunology — Posted on 2022-09-24

1083 Differential effects of ankle constraints on foot placement control between normal and split belt treadmills

Hos, M.; van Iersel, L.; van Leeuwen, A. M.; Bruijn, S. M.

10.1101/2022.07.18.500502 — biophysics — Posted on 2022-09-24

1084 A novel P{lacW} insertion in the CG18135 gene of Drosophila melanogaster is linked to pupal lethality and gene overexpression in adult males

Ionascu, A.; Ratiu, A. C.

10.1101/2022.09.13.507739 — genetics — Posted on 2022-09-24

1085 Do closely related species interact with similar partners? Testing for phylogenetic signal in bipartite interaction networks

Perez-Lamarque, B.; Maliet, O.; Pichon, B.; Selosse, M.-A.; Martos, F.; Morlon, H.

10.1101/2021.08.30.458192 — ecology — Posted on 2022-09-24

1086 Informing plasmid compatibility with bacterial hosts using protein-protein interaction data

Downing, T.; Lee, M. J.; Archbold, C.; McDonnell, A.; Rahm, A. D.

10.1101/2022.07.12.499728 — genomics — Posted on 2022-09-24

1087 Finding the right balance of conservation effort in cultivated grasslands: A modelling study on protecting dispersers in a climatically changing and anthropogenically disturbed environment

Leins, J. A.

10.1101/2022.09.20.508676 — ecology — Posted on 2022-09-24

1088 When mechanical engineering inspired from physiology improves postural-related somatosensory processes

Sutter, C.; Fabre, M.; Massi, F.; Blouin, J.; Mouchnino, L.

10.1101/2022.07.20.500443 — neuroscience — Posted on 2022-09-24

1089 scPerturb: Information Resource for Harmonized Single-Cell Perturbation Data

Peidli, S.; Green, T. D.; Shen, C.; Gross, T.; Min, J.; Garda, S.; Taylor-King, J.; Marks, D.; Luna, A.; Bluthgen, N.; Sander, C.

10.1101/2022.08.20.504663 — systems biology — Posted on 2022-09-24

1090 The establishment of Populus x Laccaria bicolor ectomycorrhiza requires the inactivation of MYC2 coordinated defense response with a key role for root terpene synthases

Marques-Galvez, J. E.; Basso, V.; Kohler, A.; Barry, K.; Keymanesh, K.; Johnson, J.; Singan, V.; Grigoriev, I. V.; Vilgalys, R.; Martin, F.; Veneault-Fourrey, C.

10.1101/2022.09.06.505662 — plant biology — Posted on 2022-09-24

1091 Intermittent Fasting Activates AMP-Kinase to Restructure Right Ventricular Lipid Metabolism and Microtubules in Two Rodent Models of Pulmonary Arterial Hypertension

Kazmirczak, F.; Hartweck, L.; Vogel, N. T.; Mendelson, J. B.; Park, J.; Raveendran, R. M.; O-Uchi, J.; Jhun, B. S.; Prisco, S.; Prins, K.

10.1101/2022.03.07.483333 — biochemistry — Posted on 2022-09-24

1092 Paths to adaptation under fluctuating nitrogen starvation: The spectrum of adaptive mutations in Saccharomyces cerevisiae is shaped by transposons and microhomology-mediated recombination

Hays, M.; Schwartz, K.; Schmidtke, D. T.; Aggeli, D.; Sherlock, G.

10.1101/2022.05.11.491585 — evolutionary biology — Posted on 2022-09-24

1093 Astrocytes amplify neurovascular coupling to sustained activation of neocortex in awake mice

Institoris, A.; Vandal, M.; Peringod, G.; Catalano, C.; Tran, C. H.; Yu, X.; Visser, F.; Breiteneder, C.; Molina, L.; Khakh, B. S.; Nguyen, M. D.; Thompson, R. J.; Gordon, G. R.

10.1101/2020.12.16.422785 — neuroscience — Posted on 2022-09-24

1094 Local field potentials and single unit dynamics in motor cortex of unconstrained macaques during different behavioral states

Yun, R.; Rembado, I.; Rao, R. P. N.; Perlmutter, S. I.; Fetz, E. E.

10.1101/2022.04.28.489967 — neuroscience — Posted on 2022-09-24

1095 RICTOR Drives ZFX-mediated Ganglioside Biosynthesis to Promote Breast Cancer Progression.

Rajput, K.; Ansari, M. N.; Jha, S. K.; Medatwal, N.; Sharma, P.; Datta, S.; Kar, A.; Pani, T.; Cholke, K.; Rana, K.; Khan, A.; Mukherjee, G.; Deo, S.; Prabhu, J. S.; Mukhopadhyay, A.; Bajaj, A.; Dasgupta, U.

10.1101/2022.01.10.475595 — cancer biology — Posted on 2022-09-24

1096 Alternative proteoforms and proteoform-dependent assemblies in humans and plants

McWhite, C. D.; Sae-Lee, W.; Yuan, Y.; Mallam, A. L.; Gort-Freitas, N. A.; Ramundo, S.; Onishi, M.; Marcotte, E. M.

10.1101/2022.09.21.508930 — systems biology — Posted on 2022-09-24

1097 Multimodal system for recording individual-level behaviors in songbird groups

Rüttimann, L.; Rychen, J.; Tomka, T.; Hörster, H.; Rocha, M. D.; Hahnloser, R. H.

10.1101/2022.09.23.509166 — animal behavior and cognition — Posted on 2022-09-23

1098 Higher levels of narrativity lead to similar patterns of EEG activity across individuals

Dini, H.; Simonetti, A.; Binge, E.; Bruni, L. E.

10.1101/2022.09.23.509168 — neuroscience — Posted on 2022-09-23

1099 Optimization of arsB (Acr3) as a positive selection marker in the cyanobacterium Synechocystis sp. PCC 6803

Tejada, I.; Florencio, F. J.; Lopez-Maury, L.

10.1101/2022.09.23.509062 — biochemistry — Posted on 2022-09-23

1100 Conformational dynamics and target-dependent myristoyl switch of calcineurin B homologous protein 3

Becker, F.; Fuchs, S.; Refisch, L.; Drepper, F.; Bildl, W.; Schulte, U.; Liang, S.; Heinicke, J. I.; Hansen, S. C.; Kreutz, C.; Warscheid, B.; Fakler, B.; Mymrikov, E. V.; Hunte, C.

10.1101/2022.09.23.509142 — biochemistry — Posted on 2022-09-23

1101 Candidatus Megaira are diverse symbionts of algae and ciliates with the potential for defensive symbiosis

Davison, H. R.; Hurst, G. D.; Siozios, S.

10.1101/2022.09.23.509160 — microbiology — Posted on 2022-09-23

1102 Antibiotic persistence does not cause phenotypic heterogeneity in tolerance of Escherichia coli to formaldehyde stress but can preserve it through time

Marx, C. J.; Jordan, I. D.; Ticak, T.; Lee, J. A.

10.1101/2022.09.23.509177 — microbiology — Posted on 2022-09-23

1103 A rapid protocol for ribosome profiling of low input samples

Meindl, A.; Romberger, M.; Lehmann, G.; Eichner, N.; Kleemann, L.; Wu, J.; Danner, J.; Boesl, M.; Mesitov, M.; Meister, G.; Koenig, J.; Leidel, S.; Medenbach, J.

10.1101/2022.09.23.509038 — systems biology — Posted on 2022-09-23

1104 The NanoLuc Assay System for Accurate Real-Time Monitoring of Mitochondrial Protein Import within Intact Mammalian Cells

Needs, H. I.; Pereira, G. C.; Henley, J.; Collinson, I.

10.1101/2022.09.23.509159 — biochemistry — Posted on 2022-09-23

1105 N-linked glycosylation increases horse radish peroxidase rigidity leading to enhanced activity and stability.

Ramakrishnan, K.; Johnson, R.; Winter, S.; Worthy, H.; Thomas, C.; Humer, D.; Spadiut, O.; Hindson, S.; Wells, S. A.; Barratt, A.; Menzies, G.; Pudney, C. R.; Jones, D.

10.1101/2022.09.23.509167 — biochemistry — Posted on 2022-09-23

1106 Post-Cyclase Skeletal Rearrangements in Plant Triterpenoid Biosynthesis by a Pair of Branchpoint Isomerases

Chuang, L.; Liu, S.; Franke, J.

10.1101/2022.09.23.508984 — biochemistry — Posted on 2022-09-23

1107 Saccharomyces cerevisiae DJ-1 paralogs maintain genome integrity through glycation repair of nucleic acids and proteins

Susarla, G.; Kataria, P.; Kundu, A.; D'Silva, P.

10.1101/2022.09.23.509147 — biochemistry — Posted on 2022-09-23

1108 Resolving chaperone-assisted protein folding on the ribosome at the peptide level

Wales, T. E.; Pajak, A.; Roeselova, A.; Shivakumaraswamy, S.; Howell, S.; Hartl, F.-U.; Engen, J. R.; Balchin, D.

10.1101/2022.09.23.509153 — biochemistry — Posted on 2022-09-23

1109 Cd-induced cytosolic proteome changes in the cyanobacterium Anabaena sp. PCC7120 are mediated by LexA as one of the regulatory proteins

Srivastava, A.; Kumar, A.; Biswas, S.; Srivastava, V.; Rajaram, H.; Mishra, Y.

10.1101/2022.09.23.509143 — molecular biology — Posted on 2022-09-23

1110 Flexible and open-source programs for quantitative image analysis in microbial ecology

Pasulka, A. L.; Hood, J. F.; Michels, D. E.; Wright, M. D.

10.1101/2022.09.23.509172 — microbiology — Posted on 2022-09-23

1111 Taurine as a key intermediate for host-symbiont interaction in the tropical sponge Ianthella basta

Moeller, F. U.; Herbold, C. W.; Schintlmeister, A.; Mooshammer, M.; Motti, C.; Behnam, F.; Watzka, M.; Schweder, T.; Albertsen, M.; Richter, A.; Webster, N. S.; Wagner, M.

10.1101/2022.09.23.509140 — microbiology — Posted on 2022-09-23

1112 A glimpse of the paleome in endolithic microbial communities

Wegner, C.-E.; Stahl, R.; Velsko, I. M.; Huebner, A.; Fagernaes, Z.; Warinner, C.; Lehmann, R.; Ritschel, T.; Totsche, K. U.; Kuesel, K.

10.1101/2022.09.23.509128 — microbiology — Posted on 2022-09-23

1113 Interleukin-17 drives sex-dependent weight loss and changes in feeding behaviour during Trypanosoma brucei infection

10.1101/2022.09.23.509158 — immunology — Posted on 2022-09-23

1114 Differential representation of natural and manmade images in the human ventral visual stream

Gopnarayan, M. N.; Rathore, D.; Bauer, F.; Hilliard, J.; Chawla, P.

10.1101/2022.09.22.509086 — neuroscience — Posted on 2022-09-23

1115 DHHC3 mediated Cadm4 palmitoylation regulates myelination in CNS

Chang, Y.; Zhu, J.; Nie, C.; Lu, Y.; Ren, F.; Cao, X.; Li, J.; Wang, C.; Yang, C.; Li, T.; Liang, Y.; Qi, S.; Kang, X.; Kong, E.

10.1101/2022.09.23.509146 — neuroscience — Posted on 2022-09-23

1116 Nhlh1 and Nhlh2, a global transcriptional mechanism regulating commissural axon projection via activating Robo3

Masuda, A.; Ajima, R.; Saga, Y.; Hirata, T.; Zhu, Y.

10.1101/2022.09.23.509112 — neuroscience — Posted on 2022-09-23

1117 Proteome dynamics during transition from exponential to stationary phase under aerobic and anaerobic conditions in yeast

den Ridder, M.; Daran-Lapujade, P.; Pabst, M.

10.1101/2022.09.23.509138 — systems biology — Posted on 2022-09-23

1118 A Haptoglobin (HP) Structural Variant Alters the Effect of APOE Alleles on Alzheimer's Disease

Bai, H.; Naj, A. C.; Benchek, P.; Dumitrescu, L.; Hohman, T.; Hamilton-Nelson, K.; Kallianpur, A. R.; Griswold, A. J.; Vardarajan, B.; Martin, E. R.; Beecham, G.; Below, J. E.; Schellenberg, G. D.; Mayeux, R.; Farrer, L.; Pericak-Vance, M. A.; Haines, J. L.; Bush, W. S.

10.1101/2022.09.22.508749 — genetics — Posted on 2022-09-23

1119 No evidence of sexual conflict for a novel sperm-derived seminal fluid protein in Caenorhabditis nematodes

Kasimatis, K. R.; Rehaluk, C.; Rowe, L.; Cutter, A. D.

10.1101/2022.09.22.509081 — evolutionary biology — Posted on 2022-09-23

1120 Quantum analysis of P3a and P3b from auditory single trial ERPs differentiates borderline personality disorder from schizophrenia

Melkonian, D.; Korner, A.; Harris, A.; Meares, R.

10.1101/2022.09.23.509191 — neuroscience — Posted on 2022-09-23

1121 Differential Inhibitory Responses to Temporal Features Enhance Cortical Coding of Dynamic Stimuli: A Network Model

Nocon, J. C.; Gritton, H.; Han, X.; Sen, K.

10.1101/2022.09.22.509092 — neuroscience — Posted on 2022-09-23

1122 Study on the mechanism of HE4 in hyperoxia-induced alveolar damage in rats

Yan, X.; Feng, X.; Gao, Y.; Liu, D.; Bai, L.; Xu, L.

10.1101/2022.09.22.509120 — zoology — Posted on 2022-09-23

1123 Emergence of Supercoiling-Mediated Regulatory Networks through Bacterial Chromosome Rearrangements

Grohens, T.; Beslon, G.; Meyer, S.

10.1101/2022.09.23.509185 — systems biology — Posted on 2022-09-23

1124 Conformational changes linked to ADP release from human cardiac myosin bound to actin-tropomyosin

Doran, M. H.; Rynkiewicz, M. J.; Rasicci, D.; Bodt, S. M. L.; Barry, M. E.; Bullitt, E.; Yengo, C. M.; Moore, J. R.; Lehman, W.

10.1101/2022.09.23.509077 — biophysics — Posted on 2022-09-23

1125 DPAM: A Domain Parser for AlphaFold Models

Zhang, J.; Schaeffer, R. D.; Durham, J.; Cong, Q.; Grishin, N. V.

10.1101/2022.09.22.509116 — bioinformatics — Posted on 2022-09-23

1126 NetAllergen, a random forest model integrating MHC-II presentation propensity for improved allergenicity prediction

Li, Y.; Nielsen, M.; Barra, C.

10.1101/2022.09.22.509069 — bioinformatics — Posted on 2022-09-23

1127 SIMBSIG: Similarity search and clustering for biobank-scale data

Adamer, M. F.; Roellin, E.; Bourguignon, L.; Borgwardt, K.

10.1101/2022.09.22.509063 — bioinformatics — Posted on 2022-09-23

1128 Functional interplay between Mediator and RSC chromatin remodeling complex controls nucleosome-depleted region maintenance at promoters

Andre, K. M.; Aiach, N. G.; Martinez-Fernandez, V.; Zeitler, L.; Goldar, A.; Werner, M.; Wilkes, C. D.; Soutourina, J.

10.1101/2022.09.22.509083 — genomics — Posted on 2022-09-23

1129 Subtle cultural boundaries reinforce genetic structure in England

Pichkar, Y.; Creanza, N.

10.1101/2022.09.23.509228 — evolutionary biology — Posted on 2022-09-23

1130 Land use influences human mental and respiratory health in a conservation priority area in southeastern Brazil

Ferreira, M. C.; Massara, R. L.; Chaves, M. A.; Mota, B. E. F.; Rodrigues, F. H. G.

10.1101/2022.09.22.508330 — ecology — Posted on 2022-09-23

1131 Grazers affect the composition of dissolved storage glycans and thereby bacterioplankton composition during a biphasic North Sea spring algae bloom

Sidhu, C.; Kirstein, I. V.; Meunier, C. L.; Rick, J.; Wiltshire, K. H.; Steinke, N.; Vidal-Melgosa, S.; Hehemann, J.-H.; Huettel, B.; Schweder, T.; Fuchs, B. M.; Amann, R. I.; Teeling, H.

10.1101/2022.09.22.509014 — ecology — Posted on 2022-09-23

1132 Neotropical birds and mammals show divergent behaviour responses to human pressure

Negret, P. J.; Luskin, M. S.; Diaz, A.; Romero, L. H.; Gomez-Valencia, B.; Restrepo, A.; Zahringer, J.; Ochoa-Quintero, J. M.; Mendes, C.

10.1101/2022.09.22.509119 — ecology — Posted on 2022-09-23

1133 Deficiency in the cell-adhesion molecule dscaml1 impairs hypothalamic CRH neuron development and neuroendocrine stress axis function

Ma, M.; Brunal, A.; Clark, K. C.; Studtmann, C.; Stebbins, K.; Higashijima, S.-i.; Pan, Y. A.

10.1101/2022.09.22.509087 — developmental biology — Posted on 2022-09-23

1134 Intestinal helminth infection impairs oral and parenteral vaccine efficacy

Hardy, L. C.; Kapita, C. M.; Campbell, E.; Hall, J. A.; Urban, J. F.; Belkaid, Y.; Nagler, C. R.; Iweala, O. I.

10.1101/2022.09.22.508369 — immunology — Posted on 2022-09-23

1135 Cytosolic condensates enriched in polyserine repeats are preferred sites of tau fiber propagation

Lester, E.; VanAlstyne, M.; McCann, K. L.; Reddy, S.; Cheng, L.; Kuo, J.; Pratt, J.; Parker, R.

10.1101/2022.09.22.509111 — neuroscience — Posted on 2022-09-23

1136 A natural language fMRI dataset for voxelwise encoding models

LeBel, A.; Wagner, L.; Jain, S.; Adhikari-Desai, A.; Gupta, B.; Morgenthal, A.; Tang, J.; Xu, L.; Huth, A. G.

10.1101/2022.09.22.509104 — neuroscience — Posted on 2022-09-23

1137 A role for myeloid miR-155 in regulating hypoxia induced seizures in neonatal C57BL/J6 mice

Dahiya, D.; Smith, J.; Strickland, T.; Morris, D.; Reschke, C.; Engel, T.; Henshell, D.; McCoy, C. E.; Dowling, J. K.

10.1101/2022.09.22.508924 — neuroscience — Posted on 2022-09-23

1138 Comprehensive evaluation of harmonization on functional brain imaging for multisite data-fusion

Wang, Y.-w.; Chen, X.; Yan, C.-G.

10.1101/2022.09.22.508637 — neuroscience — Posted on 2022-09-23

1139 Loss of hepatic phosphoenolpyruvate carboxykinase 1 dysregulates metabolic responses to acute exercise but enhances adaptations to exercise training in mice

Rome, F. I.; Shobert, G. L.; Voigt, W. C.; Stagg, D. B.; Puchalska, P.; Burgess, S. C.; Crawford, P. A.; Hughey, C. C.

10.1101/2022.09.22.509117 — physiology — Posted on 2022-09-23

1140 Luminal epithelial cells integrate variable responses to aging into stereotypical changes that underlie breast cancer susceptibility

Sayaman, R. W.; Miyano, M.; Senapati, P.; Zirbes, A.; Shalabi, S.; Todhunter, M. E.; Seewaldt, V.; Neuhausen, S. L.; Stampfer, M. R.; Schones, D. E.; LaBarge, M. A.

10.1101/2022.09.22.509091 — cancer biology — Posted on 2022-09-23

1141 High dimensional co-expression networks enable discovery of transcriptomic drivers in complex biological systems

Morabito, S.; Reese, F.; Rahimzadeh, N.; Miyoshi, E.; Swarup, V.

10.1101/2022.09.22.509094 — bioinformatics — Posted on 2022-09-23

1142 Polylactide Degradation Activates Immune Cells by Metabolic Reprogramming

Maduka, C. V.; Alhaj, M.; Ural, E.; Habeeb, M. O.; Kuhnert, M. M.; Smith, K.; Makela, A. V.; Pope, H.; Chen, S.; Hix, J. M.; Mallet, C. L.; Chung, S.-J.; Hakun, M.; Tundo, A.; Zinn, K. R.; Hankenson, K. D.; Goodman, S. B.; Narayan, R.; Contag, C. H.

10.1101/2022.09.22.509105 — bioengineering — Posted on 2022-09-23

1143 Characterising the munchies; effects of delta-9-tetrahydrocannabinol (THC) vapour inhalation on feeding patterns, satiety, and macronutrient-specific food preference in male and female rats

Hume, C.; Baglot, S. L.; Javorcikova, L.; Melts, V.; Bieber, J. B.; Hill, M. N.

10.1101/2022.09.22.509090 — animal behavior and cognition — Posted on 2022-09-23

1144 Gene expression and protein synthesis remodeling in response to iron deficiency in yeast

Barlit, H.; Romero, A. M.; Gulhan, A.; Patnaik, P. K.; Tyshkovskiy, A.; Martinez-Pastor, M. T.; Gladyshev, V. N.; Puig, S.; Labunskyy, V.

10.1101/2022.09.22.509115 — genetics — Posted on 2022-09-23

1145 Validity of fecal sampling for characterizing temporal variation in threespine stickleback's gut microbiota

Härer, A.; Rennison, D. J.

10.1101/2022.09.22.509070 — evolutionary biology — Posted on 2022-09-23

1146 Diversification is correlated with temperature in white and sulfur butterflies

Carvalho, A. P. S.; Owens, H. L.; St Laurent, R. A.; Earl, C.; Dexter, K. M.; Messcher, R. L.; Willmott, K. R.; Aduse-Poku, K.; Collins, S. C.; Homziak, N. T.; Hoshizaki, S.; Hsu, Y.-F.; Kizhakke, A. G.; Kunte, K.; Martins, D. J.; Mega, N. O.; Morinaka, S.; Peggie, D.; Romanowski, H. P.; Safian, S.; Vila, R.; Wang, H.; Braby, M. F.; Espeland, M.; Breinholt, J. W.; Pierce, N. E.; Kawahara, A. Y.; Lohman, D. J.

10.1101/2022.09.22.509088 — evolutionary biology — Posted on 2022-09-23

1147 Somatic chromosomal integration of polydnavirus during parasitism triggered their germline infiltration in multiple lepidopteran families

Gilbert, C.; Heisserer, C.; Muller, H.; Jouan, V.; Musset, K.; Volkoff, A.-N.; Drezen, J.-M.; Periquet, G.

10.1101/2022.09.22.509082 — evolutionary biology — Posted on 2022-09-23

1148 Quantifying (non)parallelism of gut microbial community change using multivariate vector analysis

Härer, A.; Rennison, D. J.

10.1101/2022.09.23.509066 — evolutionary biology — Posted on 2022-09-23

1149 Natural variation in host defense strategies impacts both host and pathogen fitness

Pfenning-Butterworth, A. C.; Vetter, R. E.; Hite, J. L.

10.1101/2022.09.22.509093 — ecology — Posted on 2022-09-23

1150 Germ-stem cells and oocyte production in the Honeybee Queen Ovary

Cullen, G.; Gilligan, J. B.; Guhlin, J. G.; Dearden, P. K.

10.1101/2022.09.22.509099 — developmental biology — Posted on 2022-09-23

1151 Patch repair protects cells from the small pore-forming toxin aerolysin

Thapa, R.; Keyel, P. A.

10.1101/2022.09.22.509098 — cell biology — Posted on 2022-09-23

1152 Drug repurposing for Cystic Fibrosis: identification of drugs that induce CFTR-independent fluid secretion in nasal organoids

Rodenburg, L. W.; Delpiano, L.; Railean, V.; Centeio, R.; Pinto, M. C.; Smits, S. M. A.; van der Windt, I. S.; van Hugten, C. F. J.; van Beuningen, S. F. B.; Rodenburg, R. N. P.; van der Ent, C. K.; Amaral, M. D.; Kunzelmann, K.; Gray, M. A.; Beekman, J. M.; Amatngalim, G. D.

10.1101/2022.09.23.509034 — cell biology — Posted on 2022-09-23

1153 An optimized workflow to generate and characterize iPSC-derived motor neuron (MN) spheroids

Castellanos-Montiel, M. J.; Chaineau, M.; Franco-Flores, A. K.; Haghi, G.; Carrillo-Valenzuela, D.; Reintsch, W. E.; Chen, C. X.-Q.; Durcan, T. M.

10.1101/2022.09.22.509079 — neuroscience — Posted on 2022-09-23

1154 Neuronal pentraxin Nptx2 regulates complement activity in the brain

Zhou, J.; Wade, S. D.; Graykowski, D.; Xiao, M.-F.; Zhao, B.; Giannini, L. A.; Hanson, J. E.; van Swieten, J. C.; Sheng, M.; Worley, P. F.; Dejanovic, B.

10.1101/2022.09.22.509106 — neuroscience — Posted on 2022-09-23

1155 IRF7 impacts on prostate cancer cell survival in response to radiation

10.1101/2022.09.23.509205 — cancer biology — Posted on 2022-09-23

1156 Statistical learning quantifies transposable element-mediated cis-regulation

Pulver, C.; Grun, D.; Duc, J.; Sheppard, S.; Planet, E.; De Fondeville, R.; Pontis, J.; Trono, D.

10.1101/2022.09.23.509180 — genomics — Posted on 2022-09-23

1157 Systematic analysis of transcriptional and epigenetic effects of genetic variation in Kupffer cells enables discrimination of cell intrinsic and environment-dependent mechanisms

Bennett, H.; Troutman, T. D.; Zhou, E.; Spann, N. J.; Link, V. M.; Seidman, J. S.; Nickl, C. K.; Abe, Y.; Sakai, M.; Pasillas, M. P.; Marlman, J. M.; Guzman, C.; Hosseini, M.; Schnabl, B.; Glass, C. K.

10.1101/2022.09.22.509046 — genomics — Posted on 2022-09-23

1158 Zooanthroponotic transmission of SARS-CoV-2 and host-specific viral mutations revealed by genome-wide phylogenetic analysis

Naderi, S.; Chen, P. E.; Murall, C. L.; Poujol, R.; Kraemer, S. A.; Pickering, B. S.; Sagan, S. M.; Shapiro, B. J.

10.1101/2022.06.02.494559 — genomics — Posted on 2022-09-23

1159 Requirement for STAT3 and its target, TFCP2L1 in self-renewal of naïve pluripotent stem cells in vivo and in vitro

Kraunsoe, S. L.; Azami, T.; Pei, Y.; Martello, G.; Jones, K. A.; Boroviak, T. E.; Nichols, J.

10.1101/2022.09.23.509173 — developmental biology — Posted on 2022-09-23

1160 Plzf mediates a switch between Fgf signalling regimes in the developing hindbrain

Leino, S.; Constable, S. C. J.; Streit, A.; Wilkinson, D. G.

10.1101/2022.09.23.509139 — developmental biology — Posted on 2022-09-23

1161 Investigation of reversible histone acetylation and dynamics in gene expression regulation using 3D liver spheroid model

Stransky, S.; Cutler, R.; Aguilan, J.; Nieves, E.; Sidoli, S.

10.1101/2022.09.22.509080 — cell biology — Posted on 2022-09-23

1162 Actomyosin cables position cell cohorts during Drosophila germband retraction by entraining their morphodynamic and mechanical properties

Nandi, S.; Balse, A.; Inamdar, M. M.; Krishnamurthy, V.; Narasimha, M.

10.1101/2022.09.23.509113 — cell biology — Posted on 2022-09-23

1163 Growth cone advance requires EB1 as revealed by genomic replacement with a light-sensitive variant

Dema, A.; Charafeddine, R. A.; Rahgozar, S.; van Haren, J.; Wittmann, T.

10.1101/2022.09.22.509085 — cell biology — Posted on 2022-09-23

1164 Imbalanced Unfolded Protein Response Signaling Contributes to 1-Deoxysphingolipid Retinal Toxicity

Rosarda, J. D.; Giles, S.; Harkins-Perry, S.; Mills, E. A.; Friedlander, M.; Wiseman, L.; Eade, K. T.

10.1101/2022.09.22.509071 — cell biology — Posted on 2022-09-23

1165 Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms

Nagasaka, K.; Davidson, I. F.; Stocsits, R.; Tang, W.; Wutz, G.; Batty, P.; Panarotto, M.; Litos, G.; Schleiffer, A.; Gerlich, D. W.; Peters, J. M.

10.1101/2022.09.23.509019 — cell biology — Posted on 2022-09-23

1166 CLASP2 facilitates dynamic actin filament organization along the microtubule lattice

Rodgers, N. C.; Lawrence, E. J.; Sawant, A. V.; Efimova, N.; Gonzalez-Vasquez, G.; Hickman, T. T.; Kaverina, I.; Zanic, M.

10.1101/2022.09.22.509100 — cell biology — Posted on 2022-09-23

1167 The Transcriptome of Acute Dehydration in Myeloid Leukemia Cells

Welch, D. B. M.; Gould, T. J.; Olins, A. L.; Olins, D. E.

10.1101/2022.09.23.509183 — cell biology — Posted on 2022-09-23

1168 Multifaceted modes of γ-tubulin complex recruitment and microtubule nucleation at mitotic centrosomes

Zhu, Z.; Tovey, C. A.; Yen, E. C.; BERNARD, F.; Guichet, A.; Conduit, P. T.

10.1101/2022.09.23.509043 — cell biology — Posted on 2022-09-23

1169 Pharmacological inhibition of bromodomain and extra-terminal proteins induces NRF-2-mediated inhibition of SARS-CoV-2 replication and is subject to viral antagonism

Mhlekude, B.; Postmus, D.; Weiner, J.; Stenzel, S.; Zapatero-Belinchon, F. J.; Olmer, R.; Jansen, J.; Richter, A.; Heinze, J.; Heinemann, N.; Muhlemann, B.; Schroeder, S.; Jones, T. C.; Muller, M. A.; Drosten, C.; Pich, A.; Thiel, V.; Martin, U.; Niemeyer, D.; Gerold, G.; Beule, D.; Goffinet, C.

10.1101/2022.09.22.508962 — microbiology — Posted on 2022-09-23

1170 Generation and functional analysis of defective viral genomes during SARS-CoV-2 infection

Zhou, T.; Gilliam, N. J.; Li, S.; Spaudau, S.; Osborn, R.; Anderson, C. S.; Mariani, T. J.; Thakar, J.; Dewhurst, S.; Mathews, D. H.; Huang, L.; Sun, Y.

10.1101/2022.09.22.509123 — microbiology — Posted on 2022-09-23

1171 A data-driven investigation of human action representations

Dima, D. C.; Hebart, M. N.; Isik, L.

10.1101/2022.09.22.509054 — neuroscience — Posted on 2022-09-23

1172 Prediction of Biopharmaceutical Characteristics of PROTACs using the ANDROMEDA by Prosilico Software

Fagerholm, U.; Hellberg, S.; Alvarsson, J.; Spjuth, O.

10.1101/2022.09.22.509053 — pharmacology and toxicology — Posted on 2022-09-23

1173 HeberFERON distinctively targets Cell Cycle in the glioblastoma-derived cell line U-87MG.

Miranda, J.; Vazquez-Blomquist, D.; Bringas, R.; Fernandez-de-Cossio, J.; Palenzuela, D.; Novoa, L. I.; Iraldo, B.-R. J.

10.1101/2022.09.22.508971 — cancer biology — Posted on 2022-09-23

1174 USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

Novellasdemunt, L.; Kucharska, A.; Baulies, A.; Vlachogiannis, G.; Repana, D.; Rowan, A.; Suarez-Bonnet, A.; Ciccarelli, F.; Valeri, N.; Li, V. S. W.

10.1101/2022.09.22.508986 — cancer biology — Posted on 2022-09-23

1175 Transcriptionally defined morphological subtypes of pancreatic ductal adenocarcinoma

Krieger, T. G.; Sudy, A.; Schicktanz, F.; Tosti, L.; Liebig, J.; Konukiewitz, B.; Rouault, M.; Niesnerova, A.; Qian, X.; Weichert, W.; Eils, R.; Steiger, K.; Conrad, C.

10.1101/2022.09.23.509133 — cancer biology — Posted on 2022-09-23

1176 Motif2Site: a Bioconductor package to detect accurate transcription factor binding sites from ChIP-seq

Zarrineh, P.; Darieva, Z.; Bobola, N.

10.1101/2022.09.22.509048 — bioinformatics — Posted on 2022-09-23

1177 Deep transfer learning provides a Pareto improvement for multiethnic genomic prediction of diseases

Gao, Y.; Cui, Y.

10.1101/2022.09.22.509055 — bioinformatics — Posted on 2022-09-23

1178 Environmental, social, and morphological drivers of fission-fusion dynamics in a social ungulate

Le Goff, M.; Hendrix, J. G.; Webber, Q. M.; Robitaille, A. L.; Vander Wal, E.

10.1101/2022.09.22.508899 — animal behavior and cognition — Posted on 2022-09-23

1179 Single molecule long-read real-time amplicon-based sequencing of CYP2D6: a proof-of-concept with hybrid haplotypes

Dong, R.; Thamilselvan, M.; Hu, X.; Carvalho Henriques, B.; Wang, Y.; Wallace, K.; Sivapalan, S.; Buchner, A.; Yavorskyy, V.; Martens, K.; Maier, W.; Henigsberg, N.; Hauser, J.; Cattaneo, A.; Mors, O.; Rietschel, M.; Pfeffer, G.; Aitchison, K. J.

10.1101/2022.08.17.503990 — genomics — Posted on 2022-09-23

1180 Selective enrichment of plasma cell-free messenger RNA in cancer-associated extracellular vesicles

Kim, H. J.; Rames, M. J.; Roskams-Hieter, B.; Briand, J.; Doe, A.; Estabrook, J.; Wagner, J. T.; Demir, E.; Mills, G.; Ngo, T. M.

10.1101/2022.09.22.509102 — genomics — Posted on 2022-09-23

1181 The Selection Landscape and Genetic Legacy of Ancient Eurasians

Irving-Pease, E. K.; Refoyo-Martinez, A.; Ingason, A.; Pearson, A.; Fischer, A.; Barrie, W.; Sjögren, K.-G.; Halgren, A. S.; Macleod, R.; Demeter, F.; Henriksen, R. A.; Vimala, T.; McColl, H.; Vaughn, A.; Speidel, L.; Stern, A. J.; Scorrano, G.; Ramsoe, A.; Schork, A. J.; Rosengren, A.; Zhao, L.; Kristiansen, K.; Sudmant, P. H.; Lawson, D. J.; Durbin, R.; Korneliussen, T.; Werge, T.; Allentoft, M. E.; Sikora, M.; Nielsen, R.; Racimo, F.; Willerslev, E.

10.1101/2022.09.22.509027 — evolutionary biology — Posted on 2022-09-23

1182 Multi-site phosphorylation of the TOPBP1 ATR Activation Domain propels ATR signaling during the response to DNA breaks

Senebandith, H.; Ruis, K.; Montales, K.; Huynh, O.; Jami-Alahmadi, Y.; Wohlschlegel, J.; Michael, W. M.

10.1101/2022.09.19.508511 — cell biology — Posted on 2022-09-23

1183 A dramatic impairment of the antitumor activity of human Vgamma9Vdelta2 T cells is induced by TGF-beta through significant phenotype, transcriptomic and metabolic changes

RAFIA, C.; LOIZEAU, C.; RENOULT, O.; HARLY, C.; PECQUEUR, C.; JOALLAND, N.; SCOTET, E.

10.1101/2022.09.22.509026 — immunology — Posted on 2022-09-23

1184 A Drosophila model of diabetic neuropathy reveals a crucial role of proteasome activity in the glia

Suzuki, M.; Kuromi, H.; Shindo, M.; Sakata, N.; Niimi, N.; Fukui, K.; Saitoe, M.; Sango, K.

10.1101/2022.09.22.509008 — neuroscience — Posted on 2022-09-23

1185 Yeast NDI1 expression prevents the unfolded protein response and reconfigures metabolism to restore neuronal function in mitochondrial complex I deficiency

Granat, L.; Ranson, D.; Hamer, E.; Chakrabarty, R. P.; Mattedi, F.; Fort-Aznar, L.; Hirth, F.; Sweeney, S.; Vagnoni, A.; Chandel, N. S.; Bateman, J. M.

10.1101/2022.09.22.509020 — neuroscience — Posted on 2022-09-23

1186 Integrated cardio-behavioural defensive states

Signoret-Genest, J.; Schukraft, N.; Reis, S. L.; Segebarth, D.; Tovote, P.

10.1101/2022.09.22.509009 — neuroscience — Posted on 2022-09-23

1187 Pattern of Self-Administered Vapor Fentanyl Exposure Determines Long-term Behavior Consequences, in Mice with or without Neuropathic Pain

Cermak, S. E.; Centeno, M. V.; Jabakhanji, R.; Vigotsky, A. D.; Cox, J. M.; Brink, A. J.; Apkarian, A. V. M.

10.1101/2022.09.22.508919 — neuroscience — Posted on 2022-09-23

1188 Expression of thioredoxin-1 in the ASJ neuron corresponds with and enhances intrinsic regenerative capacity under lesion conditioning in C. elegans

Grooms, N. W. F.; Fitzgerald, M. Q.; Schulting, L. G.; Urena, S. E.; Chung, S. H.

10.1101/2022.09.19.508543 — neuroscience — Posted on 2022-09-23

1189 A SHR-IDD-PIN regulatory network mediates minor vein differentiation in rice

Liu, Q.; Teng, S.; Deng, C.; Wu, S.; Li, H.; Wang, Y.; Wu, J.; Cui, X.; Zhang, Z.; Quick, W. P.; Brutnell, T. P.; Sun, X.; Lu, T.

10.1101/2022.09.22.509058 — plant biology — Posted on 2022-09-23

1190 Population Dynamics of Immunological Synapse Formation Induced by Bispecific T-cell Engagers Predict Clinical Pharmacodynamics and Treatment Resistance

Liu, C.; Zhou, J.; Kudlacek, S.; Qi, T.; Dunlap, T.; Cao, Y.

10.1101/2022.04.18.488626 — pharmacology and toxicology — Posted on 2022-09-23

1191 A high-resolution, nanopore-based artificial intelligence assay for DNA replication stress in human cancer cells

Jones, M. J. K.; Rai, S. K.; Pfuderer, P. L.; Bonfim-Melo, A.; Pagan, J. K.; Clarke, P. R.; McClelland, S. E.; Boemo, M. A.

10.1101/2022.09.22.509021 — cancer biology — Posted on 2022-09-23

1192 Data driven model discovery and interpretation for CAR T-cell killing using sparse identification and latent variables

Brummer, A. B.; Xella, A.; Woodall, R.; Adhikarla, V.; Cho, H.; Gutova, M. B.; Brown, C. E.; Rockne, R. C.

10.1101/2022.09.22.508748 — cancer biology — Posted on 2022-09-23

1193 Developmental reprogramming mediates aberrant cell state plasticity in colorectal cancer initiation

Bala, P.; Rennhack, J. P.; Morris, C. X.; Aitymbayev, D.; Moyer, S. M.; Duronio, G. N.; Doan, P.; Liang, X.; Hornick, J. L.; Yurgelun, M. B.; Hahn, W.; Sethi, N. S.

10.1101/2022.09.22.509032 — cancer biology — Posted on 2022-09-23

1194 DivBrowse - interactive visualization and exploratory data analysis of variant call matrices

König, P.; Beier, S.; Mascher, M.; Stein, N.; Lange, M.; Scholz, U.

10.1101/2022.09.22.509016 — bioinformatics — Posted on 2022-09-23

1195 Accurate genotype-based demultiplexing of single cell RNA sequencing samples from non-human animals

Cardiello, J. F.; Joven Araus, A.; Giatrellis, S.; Simon, A.; Leigh, N. D.

10.1101/2022.09.22.508993 — bioinformatics — Posted on 2022-09-23

1196 Accurate and robust inference of genetic ancestry from cancer-derived molecular data across genomic platforms

Belleau, P.; Deschenes, A.; Tuveson, D. A.; Krasnitz, A.

10.1101/2022.02.01.478737 — bioinformatics — Posted on 2022-09-23

1197 A formula for calculating 30-item Geriatric Depression Scale (GDS-30) scores from the 15-item version (GDS-15)

Zhang, Y.; Hoozemans, M.; Pijnappels, M.; Bruijn, S. M.

10.1101/2022.09.22.509012 — bioengineering — Posted on 2022-09-23

1198 When Mechanical Stress Matters: Generation of Polyploid Giant Cancer Cells in Tumor-like Microcapsules

Buehler, A.; Krueger, R.; Monavari, M.; Fuentes-Chandia, M.; Palmisano, R.; Schoedel, J.; Boccaccini, A. R.; Bosserhoff, A. K.; Kappelmann-Fenzl, M.; Letort, G.; Leal-Egana, A.

10.1101/2022.09.22.508846 — bioengineering — Posted on 2022-09-23

1199 Finding priority ribosomes for future structural and pathogen research based upon global RNA and protein sequence analysis

Cooper, H. B.; Krause, K. L.; Gardner, P. P.

10.1101/2021.06.14.448437 — biochemistry — Posted on 2022-09-23

1200 Synthesis of natural history collections data reveals patterns of US freshwater mussel diversity and decline

Pfeiffer, J. M.; Dubose, T. P.; Keogh, S. M.

10.1101/2022.09.22.509037 — ecology — Posted on 2022-09-23

1201 Deletion of Tac1 gene impact kinase phosphorylation involved in signaling pathways associated with pain

Ben Salem, J.; Zhang, J.; Beaudry, F.

10.1101/2022.09.22.509023 — neuroscience — Posted on 2022-09-23

1202 PFTK1 kinase regulates axogenesis during development via RhoA activation.

Rodriguez Gonzalez, Y.; Kamkar, F.; Jafar-nejad, P.; Wang, S.; Qu, D.; Sanchez Alvarez, L.; Hawari, D.; Sonnenfeld, M.; Slack, R. S.; Albert, P.; Park, D. S.; Joselin, A.

10.1101/2022.01.11.475789 — neuroscience — Posted on 2022-09-23

1203 Imprinted SARS-CoV-2 humoral immunity induces converging Omicron RBD evolution

Cao, Y.; Jian, F.; Wang, J.; Yu, Y.; Song, W.; Yisimayi, A.; Wang, J.; An, R.; Zhang, N.; Wang, Y.; Wang, P.; Zhao, L.; Sun, H.; Yu, L.; Yang, S.; Niu, X.; Xiao, T.; Gu, Q.; Shao, F.; Hao, X.; Xu, Y.; Jin, R.; Wang, Y.; Xie, X. S.

10.1101/2022.09.15.507787 — immunology — Posted on 2022-09-23

1204 Normative models for neuroimaging markers: Impact of model selection, sample size and evaluation criteria

Bozek, J.; Griffanti, L.; Lau, S.; Jenkinson, M.

10.1101/2022.09.22.509002 — neuroscience — Posted on 2022-09-23

1205 Tumoroscope: a probabilistic model for mapping cancer clones in tumor tissues

Darvish Shafighi, S.; Geras, A.; Jurzysta, B.; Sahaf Naeini, A.; Filipiuk, I.; Raczkowski, L.; Toosi, H.; Koperski, L.; Thrane, K.; Engblom, C.; Mold, J.; Chen, X.; Hartman, J.; Nowis, D.; Carbone, A.; Lagergren, J.; Szczurek, E.

10.1101/2022.09.22.508914 — cancer biology — Posted on 2022-09-23

1206 Proteomics Characteristics Reveal the Risk of T1 Colorectal Cancer Metastasis to Lymph Nodes

Zhuang, A.; Zhuang, A.; Qin, Z.; Zhu, D.; Ren, L.; Wei, Y.; Zhou, P.; Yue, X.; He, F.; Xu, J.; Ding, C.

10.1101/2022.09.22.508997 — cancer biology — Posted on 2022-09-23

1207 eccDB: a comprehensive repository for eccDNA-mediated chromatin contacts in multi-species

Yang, M.; Qiu, B.; He, G.-Y.; Zhou, J.-Y.; Yu, H.-J.; Zhang, Y.-Y.; Li, Y.-S.; Li, T.-S.; Guo, J.-C.; Li, X.-C.; Xie, J.-J.

10.1101/2022.09.22.509011 — bioinformatics — Posted on 2022-09-23

1208 Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability

Sonrel, A.; Luetge, A.; Soneson, C.; Mallona Gonzalez, I.; Germain, P.-L.; Knyazev, S.; Gilis, J.; Gerber, R.; Seurinck, R.; Paul, D.; Sonder, E.; Crowell, H. L.; Fanaswala, I.; Al Ajami, A.; Heidari, E.; Schmeing, S.; Milosavljevic, S.; Saeys, Y.; Mangul, S.; Robinson, M. D.

10.1101/2022.09.22.508982 — bioinformatics — Posted on 2022-09-23

1209 Optical modulation of excitation-contraction coupling in human induced pluripotent stem cell-derived cardiomyocytes

Vurro, V.; Federici, B.; Ronchi, C.; Sesti, V.; Crasto, S.; Maniezzi, C.; Antognazza, M. R.; Bertarelli, C.; Di Pasquale, E.; Lanzani, G.; Lodola, F.

10.1101/2022.09.22.508828 — bioengineering — Posted on 2022-09-23

1210 Conformable neural interface based on off-stoichiometry thiol-ene-epoxy thermosets

Borda, E.; Airaghi Leccardi, M. J.; Medagoda, D. I.; Zollinger, E. G.; Ghezzi, D.

10.1101/2022.09.22.508978 — bioengineering — Posted on 2022-09-23

1211 The Effect of Bottleneck Size on Evolution in Nested Darwinian Populations

Nitschke, M. C.; Black, A.; Bourrat, P.; Rainey, P. B.

10.1101/2022.09.22.508977 — evolutionary biology — Posted on 2022-09-23

1212 Maternal control over caste allocation in the ant Cardiocondyla obscurior

Schultner, E.; Wallner, T.; Dofka, B.; Bruelhart, J.; Heinze, J.; Freitak, D.; Pokorny, T.; Oettler, J.

10.1101/2021.08.13.456267 — evolutionary biology — Posted on 2022-09-23

1213 ADAR2 deaminase activity promotes Th17 effector function and protects against intestine inflammation

Ma, S.; Hao, Y.; Cho, B. S.; Chen, N.; Zheng, A.; Zhang, S.; Sun, G.; Patel, P. R.; Li, Y.; Yee, B. A.; Yeo, G. W.; Zhou, B.; Fu, X.-D.; Huang, W. J. M.

10.1101/2020.09.22.308221 — immunology — Posted on 2022-09-23

1214 UBA52 attunes VDAC1-mediated mitochondrial dysfunction and dopaminergic neuronal death

Tiwari, S.; Singh, A.; Gupta, P.; K, A.; SINGH, S.

10.1101/2022.09.22.508987 — neuroscience — Posted on 2022-09-23

1215 The Mechanisms Underlying Colour Afterimages

Witzel, C.

10.1101/2022.09.22.508985 — neuroscience — Posted on 2022-09-23

1216 Biomechanics and neural circuits for vestibular-induced fine postural control in larval zebrafish

Sugioka, T.; Tanimoto, M.; Higashijima, S.-i.

10.1101/2022.09.22.508983 — neuroscience — Posted on 2022-09-23

1217 One Health Approach for the sampling of different bat species living in a sympatric colony

Perera, T.; Siriwardana, S.; Muzeniek, T.; Becker-Ziaja, B.; Bas, D.; Bayram, F.; Oeruc, M.; Perera, I.; Weerasena, J.; Handunnetti, S.; Schwarz, F.; Premawansa, G.; Premawansa, S.; Yapa, W.; Nitsche, A.; Kohl, C.

10.1101/2022.09.22.508887 — zoology — Posted on 2022-09-23

1218 A CDKB/KRP/FB3 cell cycle core complex functions in rice gametes and zygotes

Xu, H.; Bartley, L.; Libault, M.; Sundaresan, V.; Fu, H.; Russell, S. D.

10.1101/2022.07.12.499798 — cell biology — Posted on 2022-09-23

1219 Temporal dynamics of the multi-omic response to endurance exercise training across tissues

MoTrPAC Study Group, ; Amar, D.; Gay, N. R.; Jean Beltran, P. M.; Adkins, J. N.; Almagro Armenteros, J. J.; Ashley, E.; Avila-Pacheco, J.; Bae, D.; Bararpour, N.; Burant, C.; Clish, C.; Cutter, G.; Dasari, S.; Dennis, C.; Evans, C. R.; Fernandez, F. M.; Gaul, D.; Ge, Y.; Gerszten, R.; Goodyear, L. J.; Hou, Z.; Ilkayeva, O.; Ivanova, A. A.; Jimenez-Morales, D.; Kachman, M. T.; Keshishian, H.; Kraus, W. E.; Lanza, I. R.; Li, J.; Lindholm, M. E.; Lira, A. C.; Many, G. M.; Marwaha, S.; Miller, M. E.; Muehlbauer, M. J.; Nair, K. S.; Nair, V. D.; Natarajan Raja, A.; Newgard, C.; Ortlund, E. A.; Pie

10.1101/2022.09.21.508770 — molecular biology — Posted on 2022-09-23

1220 Aperiodic brain activity and response to anesthesia vary in disorders of consciousness

Maschke, C.; Duclos, C.; Owen, A. M.; Jerbi, K.; Blain-Moraes, S.

10.1101/2022.04.22.489199 — neuroscience — Posted on 2022-09-23

1221 Frontal cortical regulation of neurogenesis and cellular proliferation in the ventral subventricular zone

Naffaa, M.; Khan, R.; Kuo, C. T.; Yin, H. H.

10.1101/2021.12.27.474262 — neuroscience — Posted on 2022-09-23

1222 The parthenogenesis mechanism and venom complement of the parasitoid wasp Microctonus hyperodae, a declining biocontrol agent.

Inwood, S. N.; Harrop, T. W. R.; Dearden, P. K.

10.1101/2022.09.11.507509 — zoology — Posted on 2022-09-23

1223 Exact global alignment using A* with seed heuristic and match pruning

Groot Koerkamp, R.; Ivanov, P.

10.1101/2022.09.19.508631 — bioinformatics — Posted on 2022-09-23

1224 In vitro characterization of the full-length human dynein-1 cargo adaptor BicD2

Fagiewicz, R.; Crucifix, C.; Deville, C.; Kieffer, B.; Nomine, Y.; Busselez, J.; Rossolillo, P.; Schmidt, H.; Klos, T.

10.1101/2022.01.05.474964 — biochemistry — Posted on 2022-09-23

1225 Streamlined, cell-specific single-molecule RNA-FISH of core clock mRNAs in clock neurons in whole mount Drosophila brains

Yuan, Y.; Padilla, M. A.; Clark, D.; Yadlapalli, S.

10.1101/2022.09.05.506677 — cell biology — Posted on 2022-09-23

1226 Dopaminergic innervation at the central nucleus of the amygdala reveals distinct topographically and functionally segregated regions

Casey, E.; Avale, M. E.; Kravitz, A. V.; Rubinstein, M.

10.1101/2022.09.22.508929 — neuroscience — Posted on 2022-09-23

1227 Glutamatergic Supramammillary Nucleus Neurons Promote Active Coping to Stress

Holloway, S.-A.; Votoupal, M.; Escobedo, A.; Legaria, A.; Ndiokho, I.; Floyd, T.; Kravitz, A. V.; Bruchas, M. R.; Norris, A. J.

10.1101/2022.09.22.507167 — neuroscience — Posted on 2022-09-23

1228 Comparison Between Gradients and Parcellations for Functional Connectivity Prediction of Behavior

Kong, R.; Tan, Y. R.; Wulan, N.; Ooi, L. Q. R.; Farahibozorg, S.-R.; Harrison, S.; Bijsterbosch, J. D.; Bernhardt, B. C.; Eickhoff, S.; Yeo, B. T. T.

10.1101/2022.09.22.509045 — neuroscience — Posted on 2022-09-23

1229 Pathogenic mis-splicing of CPEB4 in schizophrenia

Olla, I.; Pardinas, A. F.; Parras, A.; Hernandez, I. H.; Santos-Galindo, M.; Pico, S.; Callado, L. F.; Elorza, A.; Fernandez-Miranda, G.; Belloc, E.; Walters, J. T. R.; O'Donovan, M.; Toma, C.; Mendez, R.; Meana, J. J.; Owen, M. J.; Lucas, J. J.

10.1101/2022.09.22.508890 — neuroscience — Posted on 2022-09-23

1230 Disentangling object category representations driven by dynamic and static visual input

Robert, S.; Ungerleider, L. G.; Vaziri-Pashkam, M.

10.1101/2022.05.03.490462 — neuroscience — Posted on 2022-09-23

1231 Systematic evaluation of genome sequencing for the assessment of fetal structural anomalies

Lowther, C.; Valkanas, E.; Giordano, J. L.; Wang, H. Z.; Currall, B. B.; O'Keefe, K.; Pierce-Hoffman, E.; Kurtas, N. E.; Whelan, C. W.; Hao, S. P.; Weisburd, B. W.; Jalili, V.; Fu, J.; Wong, I.; Collins, R. L.; Zhao, X.; Austin-Tse, C. A.; Evangelista, E.; Lemire, G.; Aggarwal, V.; Lucente, D.; Gauthier, L. D.; Tolonen, C.; Sahakian, N.; Stevens, C.; An, J.-Y.; Dong, S.; Norton, M. E.; MacKenzie, T.; Devlin, B.; Gilmore, K.; Powell, B.; Brandt, A.; Vetrini, F.; DiVito, M.; Sanders, S. J.; MacArthur, D. G.; Hodge, J. C.; O'Donnell-Luria, A.; Rehm, H.; Vora, N.; Levy, B.; Brand, H.; Wapner, R.;

10.1101/2020.08.12.248526 — genomics — Posted on 2022-09-23

1232 A gradient in glucose metabolism regulates hair cell morphology along the tonotopic axis of the developing cochlea

O'Sullivan, J. D.; Blacker, T. S.; Scott, C. A.; Chang, W.; Ahmed, M.; Yianni, V.; Mann, Z. F.

10.1101/2022.04.11.487851 — developmental biology — Posted on 2022-09-23

1233 Robust Estimation of 1/f Activity Improves Oscillatory Burst Detection

Seymour, R. A.; Alexander, N.; Maguire, E. A.

10.1101/2022.03.24.485674 — neuroscience — Posted on 2022-09-23

1234 Defining composition and function of the rhizosphere microbiota of barley genotypes exposed to growth-limiting nitrogen supplies

Alegria Terrazas, R.; Robertson-Albertyn, S.; Corral, A. M.; Escudero-Martinez, C.; Kapadia, R.; Balbirnie-Cumming, K.; Morris, J.; Hedley, P. E.; Barret, M.; Torres, G.; Paterson, E.; Baggs, L. M.; Abbott, J.; Bulgarelli, D.

10.1101/605204 — plant biology — Posted on 2022-09-23

1235 Integrating comparative modeling and accelerated simulations reveals conformational and energetic basis of actomyosin force generation

Ma, W.; You, S.; Regnier, M.; McCammon, J. A.

10.1101/2022.09.22.508219 — biophysics — Posted on 2022-09-23

1236 Deciphering bacteriophage T5 host recognition mechanism and infection trigger

Degroux, S.; Effantin, G.; Linares, R.; Schoehn, G.; Breyton, C.

10.1101/2022.09.22.509047 — biophysics — Posted on 2022-09-23

1237 In-silico and in-vitro evaluation of anti-oxidant and anti-hypertensive activities of Chenopodium ambrosoides LINN. ethanol leaf extract

Olaniyi, A. c.; Oluwatobi, O. A.; Oluwabunmi, A. T.

10.1101/2022.09.22.509042 — biochemistry — Posted on 2022-09-23

1238 Molecular Mechanisms of Holliday Junction Branch Migration Catalyzed by an Asymmetric RuvB Hexamer

Rish, A. D.; Shen, Z.; Chen, Z.; Fu, T.-M.

10.1101/2022.09.22.509074 — biochemistry — Posted on 2022-09-23

1239 In-silico analysis of cyanobacteriochrome architectures and spectral diversity

Mihnev, A.; Amtmann, A.

10.1101/2022.09.22.509050 — biochemistry — Posted on 2022-09-23

1240 Attentional enhancement of tracked stimuli in early visual cortex has limited capacity

Adamian, N.; Andersen, S. K.

10.1101/2022.09.08.507113 — animal behavior and cognition — Posted on 2022-09-23

1241 Coevolution of reproducers and replicators at the origin of life and the conditions for the origin of genomes

Babajanyan, S.; Wolf, Y. I.; Khachatryan, A.; Allahverdyan, A.; Koonin, E. V.

10.1101/2022.09.22.509036 — evolutionary biology — Posted on 2022-09-23

1242 Population Genomics of Stone Age Eurasia

10.1101/2022.05.04.490594 — evolutionary biology — Posted on 2022-09-23

1243 Identification and structural modeling of the chlamydial RNA polymerase omega subunit

Cheng, A.; Wu, D.; Ghatak, A.; Wang, C.; Feng, D.; Fondell, J. D.; Ebright, R. H.; Fan, H.

10.1101/2022.09.22.509108 — molecular biology — Posted on 2022-09-23

1244 PbAP2-FG2 and AP2R-2 function together as a transcriptional repressor complex essential for Plasmodium female development

Nishi, T.; Kaneko, I.; Iwanaga, S.; Yuda, M.

10.1101/2022.09.22.508975 — microbiology — Posted on 2022-09-23

1245 Toroidal displacement of Klebsiella pneumoniae by Pseudomonas aeruginosa is a unique mechanism to avoid competition for iron

Pradhan, D.; Tanwar, A.; Parthasarathy, S.; Singh, V.

10.1101/2022.09.21.508880 — microbiology — Posted on 2022-09-23

1246 Cardiovirus leader proteins retarget RSK kinases toward alternative substrates to perturb nucleocytoplasmic traffic

Lizcano-Perret, B.; Lardinois, C.; Wavreil, F.; Hauchamps, P.; Herinckx, G.; Sorgeloos, F.; Vertommen, D.; Gatto, L.; Michiels, T.

10.1101/2022.06.16.496404 — microbiology — Posted on 2022-09-23

1247 Susceptibility of Pseudomonas aeruginosa and Acinetobacter baumannii biofilms grown on denture acrylic to denture-cleaning agents and sonication

Behbehani, M.; McDonald, A.; Nair, S. P.; Green, I. M.

10.1101/2022.09.21.508680 — microbiology — Posted on 2022-09-23

1248 Histone lactylation: A new epigenetic axis for host-parasite signalling in malaria?

Merrick, C. J.

10.1101/2022.09.22.509018 — microbiology — Posted on 2022-09-22

1249 Cas9-mediated endogenous plasmid loss in Borrelia burgdorferi

Takacs, C. N.; Nakajima, Y.; Haber, J. E.; Jacobs-Wagner, C.

10.1101/2022.09.22.509095 — microbiology — Posted on 2022-09-22

1250 ESCRT-dependent STING degradation curtails steady-state and cGAMP-induced signaling

Gentili, M.; Liu, B.; Papanastasiou, M.; Dele-Oni, D.; Schwartz, M. A.; Carlson, R. J.; Al'Khafaji, A.; Krug, K.; Brown, A.; Doench, J. G.; Carr, S. A.; Hacohen, N.

10.1101/2022.09.22.509044 — immunology — Posted on 2022-09-22

1251 The immune response to lumpy skin disease virus in cattle is influenced by inoculation route

Fay, P. C.; Wijesiriwardana, N.; Munyanduki, H.; Sanz-Bernardo, B.; Lewis, I.; Haga, I. R.; Moffat, K.; van Vliet, A. H. M.; Hope, J.; Graham, S.; Beard, P.

10.1101/2022.09.22.509006 — immunology — Posted on 2022-09-22

1252 Designing a Minimal Artificial Glycolytic Pathway

yang, y.; Liu, Y.; zhang, j.; Yang, Q.; Cheng, J.; Chu, H.; Zhao, H.; Luo, M.; Lu, X.; Liu, D.; Sheng, X.; Zhang, Y.-H. P. J.; jiang, h.; Ma, Y.

10.1101/2022.09.22.508994 — synthetic biology — Posted on 2022-09-22

1253 Epigenetic mechanisms controlling human leukemia stem cells and therapy resistance

Takao, S.; Morell, V.; Brown, F. C.; Koche, R.; Kentsis, A.

10.1101/2022.09.22.509005 — cancer biology — Posted on 2022-09-22

1254 Anticodon-like loop-mediated dimerization in the crystal structures of HdV- like CPEB3 ribozymes

Przytula-Mally, I.; Engilberge, S.; Johannsen, S.; Olieric, V.; Masquida, B.; Sigel, R. K. O.

10.1101/2022.09.22.508989 — biophysics — Posted on 2022-09-22

1255 Phytohormones enhance heavy metal responses in Euglena gracilis: evidence from uptake of Ni, Pb and Cd and linkages to hormonomic and metabolomic dynamics

Nguyen, H. N.; Nguyen Quoc, T.; Dang, D. H.; Robert Joseph Neil, E.

10.1101/2022.09.22.508751 — biochemistry — Posted on 2022-09-22

1256 Altered MAM function shifts mitochondrial metabolism in SOD1-mutant models of ALS

Larrea, D.; Tamucci, K. A.; Kabra, K.; Velasco, K.; Yun, T. D.; Pera, M.; Montesinos, J.; Agrawal, R. R.; Smerdon, J. W.; Lowry, E. R.; Stepanova, A.; Yoval-Sanchez, B.; Galkin, A.; Wichterle, H.; Area-Gomez, E.

10.1101/2022.09.22.508778 — molecular biology — Posted on 2022-09-22

1257 The cell envelope of Thermotogae suggests a mechanism for outer membrane biogenesis

Sexton, D. L.; Hashimi, A.; Sibanda, L.; Beskrovnaya, P.; Huan, T.; Tocheva, E. I.

10.1101/2022.09.22.508938 — microbiology — Posted on 2022-09-22

1258 Genome evolution and transcriptome plasticity associated with adaptation to monocot and eudicot plants in Colletotrichum fungi

Baroncelli, R.; Cobo-Diaz, J. F.; Benocci, T.; Peng, M.; Battaglia, E.; Haridas, S.; Andreopoulos, W.; LaButti, K.; Pangilinan, J.; Lipzen, A.; Koriabine, M.; Bauer, D.; Le Floch, G.; Makela, M. R.; Drula, E.; Henrissat, B.; Grigoriev, I. V.; Crouch, J. A.; de Vries, R. P.; Sukno, S. A.; Thon, M. R.

10.1101/2022.09.22.508453 — microbiology — Posted on 2022-09-22

1259 Deep phylotaxonogenomic revision of the genus Xanthomonas within family Xanthomonadaceae and proposal of novel family Frateuriaceae within order Xanthomonadales

Bansal, K.; Kumar, S.; Singh, A.; Chaudhary, A.; Patil, P. B.

10.1101/2022.09.22.508540 — microbiology — Posted on 2022-09-22

1260 Exploitation of ATP-sensitive potassium ion (KATP) channels by HPV promotes cervical cancer cell proliferation by contributing to MAPK/AP-1 signalling

Scarth, J. A.; Wasson, C. W.; Patterson, M. R.; Evans, D.; Barba-Moreno, D.; Carden, H.; Whitehouse, A.; Mankouri, J.; Samson, A.; Morgan, E. L.; Macdonald, A.

10.1101/2022.09.22.508991 — microbiology — Posted on 2022-09-22

1261 Commercial influenza vaccines vary in both the structural arrangements of HA complexes and in induction of antibodies to cross-reactive HA epitopes

Myers, M. L.; Gallagher, J. R.; Kim, A. J.; Payne, W. H.; Bock, K. W.; Torian, U.; Moore, I. N.; Harris, A. K.

10.1101/2022.09.22.509041 — microbiology — Posted on 2022-09-22

1262 Strand-biased circularizing integrative elements spread tmexCD-toprJ gene clusters encoding RND-type multidrug efflux pumps by repeated transpositions

Dao, T. D.; Yano, H.; Takemura, T.; Hirabayashi, A.; Trang, L. T.; Tran, H. H.; Shibayama, K.; Hasebe, F.; Kasuga, I.; Suzuki, M.

10.1101/2022.09.22.508988 — microbiology — Posted on 2022-09-22

1263 Collaborative partnership model to transform bioinformatics core into a highly effective research partner and multiply the impact

Karuturi, R. K. M.; Ramamoorthy, G. K.; TeHennepe, G.; George, J.; Philip, V.

10.1101/2022.09.21.508957 — scientific communication and education — Posted on 2022-09-22

1264 The Phosphate Deprivation Response is Mediated by an Interaction between Brassinosteroid Signaling and Zinc in Tomato

Demirer, G. S.; Gibson, D. J.; Yue, X.; Pan, K.; Elishav, E.; Khandal, H.; Horev, G.; Tarkowska, D.; Canto-Pastor, A.; Kong, S.; Maloof, J.; Savaldi-Goldstein, S.; Brady, S.

10.1101/2022.09.21.508943 — plant biology — Posted on 2022-09-22

1265 Proton exchange in the nitrate vacuolar transporter AtCLCa is required for growth and nitrogen use efficiency

Hodin, J.; Lind, C.; Marmagne, A.; Espagne, C.; Bianchi, M. W.; De Angeli, A.; Abou Choucha, F.; Bourge, M.; Chardon, F.; Thomine, S.; Filleur, S.

10.1101/2022.09.21.508937 — plant biology — Posted on 2022-09-22

1266 Palbociclib interferes with replication origin firing in a pRb independent manner

Kim, S.-J.; Maric, C.; Briu, l.-m.; Fauchereau, F.; Baldacci, G.; Debatisse, M.; KOUNDRIOUKOFF, S.; cadoret, J. C.

10.1101/2022.09.21.508850 — cancer biology — Posted on 2022-09-22

1267 Super resolution ultrasound imaging using deep learning based micro-bubbles localization

Long, F.; Zhang, W.

10.1101/2022.09.21.508222 — biophysics — Posted on 2022-09-22

1268 Screening and Development of Constitutively Synergistic Combination Drug Formulations for T Cell Acute Lymphoblastic Leukemia

Kelvin, J. M.; Zhang, D. Y.; Williams, E. K.; Moore, S. G.; Birnbaum, L. A.; Zecca, H.; Wang, X.; Jain, J.; Qui, M.; Jui, N. T.; Fu, H.; Du, Y.; Kemp, M. L.; Lam, W. A.; DeRyckere, D.; Graham, D. K.; Dreaden, E. C.

10.1101/2022.09.21.508196 — bioengineering — Posted on 2022-09-22

1269 The origin of a new chromosome in gerbils

Brekke, T. D.; Papadopulos, A. S.; Julia, E.; Fornas, O.; Fu, B.; Yang, F.; de la Fuente, R.; Page, J.; Baril, T.; Hayward, A.; Mulley, J.

10.1101/2022.09.21.508825 — genomics — Posted on 2022-09-22

1270 Feature detecting columnar neurons mediate object tracking saccades in Drosophila

Frighetto, G.; Frye, M. A.

10.1101/2022.09.21.508959 — neuroscience — Posted on 2022-09-22

1271 Multi-modal brain magnetic resonance imaging database covering marmosets with a wide age range

Hata, J.; Nakae, K.; Tsukada, H.; Woodward, A.; Haga, Y.; Iida, M.; Uematsu, A.; Seki, F.; Ichinohe, N.; Gong, R.; Kaneko, T.; Yoshimaru, D.; Watakabe, A.; Abe, H.; Tani, T.; skibbe, h.; Maeda, M.; Papazian, F.; Hagiya, K.; Kishi, N.; Shimogori, T.; Yamamori, T.; Okano, H. j.; Okano, H.

10.1101/2022.09.21.508952 — neuroscience — Posted on 2022-09-22

1272 Brain mapping and spatial protein profiling reveal functional connectivity deficits and molecular changes following repetitive mild traumatic brain injury in wild-type mice.

Ravi, S.; Criado-Marrero, M.; Barroso, D.; Braga, I. M.; Bolen, M.; Rubinovich, U.; Hery, G. P.; Grudny, M. M.; Koren, J.; Prokop, S.; Febo, M.; Abisambra, J. F.

10.1101/2022.09.21.508917 — neuroscience — Posted on 2022-09-22

1273 Development of muti-agent-simulation models for intercellular communication via cytokines and extracellular matrices

Inoue, K.-i.; Kishimoto, S.; Mogami, T.; Toyoda, S.; Hariyama, M.

10.1101/2022.09.21.508950 — systems biology — Posted on 2022-09-22

1274 Bitter taste receptor-stimulated nitric oxide innate immune responses are reduced by loss of CFTR function in nasal epithelial cells and macrophages

Carey, R. M.; Palmer, J. N.; Adappa, N. D.; Lee, R. J.

10.1101/2022.09.21.508717 — physiology — Posted on 2022-09-22

1275 Carcinoma associated mesenchymal stem cells promote ovarian cancer metastasis by increasing tumor heterogeneity through direct mitochondrial transfer

Pressimone, C.; Frisbie, L. G.; Dyer, E.; Baruwal, R.; Gorecki, G.; Javed, Z.; St. Croix, C.; Watkins, S. C.; Calderon, M.; Atiua, H. I.; Hempel, N.; Pearson, A. T.; Coffman, L.

10.1101/2022.09.21.506345 — cancer biology — Posted on 2022-09-22

1276 Assembly mechanism of the AIM2 inflammasome sensorrevealed by single-molecule analysis

Sharma, M.; de Alba, E.

10.1101/2022.09.21.508942 — biophysics — Posted on 2022-09-22

1277 Topological Gelation of Reconnecting Polymers

Bonato, A.; Marenduzzo, D.; Michieletto, D.; Orlandini, E.

10.1101/2022.09.21.508941 — biophysics — Posted on 2022-09-22

1278 Effective drug combinations targeting driver KRAS mutations in non-small cell lung cancer

BRUGGEMANN, L.; Falls, Z.; Mangione, W.; Schwartz, S. A.; Battaglia, S.; Aalinkeel, R.; Mahajan, S. D.; Samudrala, R.

10.1101/2022.09.21.508953 — bioinformatics — Posted on 2022-09-22

1279 Syndecan-4 Proteoliposomes Enhance Revascularization in a Rabbit Hind Limb Ischemia Model of Peripheral Ischemia

Sligar, A.; Howe, G.; Goldman, J.; Felli, P.; Gomez-Hernandez, A.; Takematsu, E.; Veith, A.; Desai, S.; Riley, W.; Singeetham, R.; Mei, L.; Callahan, G.; Ashirov, D.; Smalling, R.; Baker, A.

10.1101/2022.09.21.508898 — bioengineering — Posted on 2022-09-22

1280 New estimates of genome size in Orthoptera and their evolutionary implications

Hawlitschek, O.; Sadilek, D.; Lara-Sophie, D.; Buchholz, K.; Noori, S.; Baez, I. L.; Wehrt, T.; Brozio, J.; Travnicek, P.; Seidel, M.; Husemann, M.

10.1101/2022.09.21.508865 — genomics — Posted on 2022-09-22

1281 Fibroblast activation during decidualization: Embryo-derived TNFα induction of PGI2-PPARδ-ACTIVIN A pathway through luminal epithelium

Chen, S.-T.; Shi, W.-W.; Lin, Y.-Q.; Yang, Z.-S.; Wang, Y.; Li, M.-Y.; Li, Y.; Liu, A.-X.; Hu, Y.; Yang, Z.-M.

10.1101/2022.09.22.509003 — developmental biology — Posted on 2022-09-22

1282 Massively-parallel Microbial mRNA Sequencing (M3-Seq) reveals heterogenous behaviors in bacteria at single-cell resolution

Gitai, Z.; Wingreen, N. S.; Adamson, B.; Lin, A. E.; Koch, M. D.; Yuan, J.; Wang, B.

10.1101/2022.09.21.508688 — microbiology — Posted on 2022-09-22

1283 Heme-induced genes facilitate endosymbiont (Sodalis glossinidius) colonization of the tsetse fly (Glossina morsitans) midgut

Weiss, B. L.; Runyen-Janecky, L. J.; Scheutzow, J.; Farsin, R.; Cabo, L. F.; Kuhn, K. M.; Amador, R.; D'Souza, S. J.; Vigneron, A.; Wall, K. E.

10.1101/2022.09.22.508973 — microbiology — Posted on 2022-09-22

1284 Glucose PTS Modulates Pyruvate Metabolism, Bacterial Fitness, and Microbial Ecology in Oral Streptococci

Zeng, L.; Walker, A. R.; Burne, R. A.; Taylor, Z. A.

10.1101/2022.09.21.508965 — microbiology — Posted on 2022-09-22

1285 A special satellite-like dsRNA of a novel hypovirus from Pestalotiopsis fici broadens the definition of satellite

Han, Z.; Liu, J.; Kong, L.; He, Y.; Wu, H.; Xu, W.

10.1101/2022.09.22.508974 — microbiology — Posted on 2022-09-22

1286 Mouse lung Tissue Resident Memory (TRM) CD8 T cell subsets have distinct metabolic profiles from each other and from non-TRM

Sportiello, M.; Poindexter, A.; Reilly, E. C.; Geber, A.; Lambert Emo, K.; Jones, T. N.; Topham, D. J.

10.1101/2022.09.21.508875 — immunology — Posted on 2022-09-22

1287 Transcription factor TFII-I fine tunes innate properties of B lymphocytes

Singh, A.; Kaileh, M.; De, S.; Mazan-Mamczarz, K.; Bayarsaihan, D.; Sen, R.; Roy, A.

10.1101/2022.09.21.508949 — immunology — Posted on 2022-09-22

1288 Magnitude and kinetics of the human immune cell response associated with severe dengue progression by single-cell proteomics

Robinson, M. L.; Glass, D. R.; Duran, V.; Rojas, O.; Sanz, A. M.; Consuegra, M.; Sahoo, M. K.; Hartmann, F.; Bosse, M.; Ramirez, R. M. G.; Bueno, N.; Pinsky, B. A.; Montoya, J. G.; Maecker, H.; Cardenas, M.; Villar, L.; Garrido, E. R.; Rosso, F.; Bendall, S. C.; Einav, S.

10.1101/2022.09.21.508901 — immunology — Posted on 2022-09-22

1289 Deep proteomics identifies shared molecular pathway alterations in synapses of schizophrenia and bipolar disorder patients and mouse model

Aryal, S.; Bonanno, K.; Song, B.; Mani, D. R.; Keshishian, H.; Carr, S. A.; Sheng, M.; Dejanovic, B.

10.1101/2022.09.21.508852 — neuroscience — Posted on 2022-09-22

1290 SRF transcriptionally regulates the oligodendrocyte cytoskeleton during CNS myelination

Iram, T.; Garcia, M. A.; Amand, J.; Kaur, A.; Iyer, M.; Lam, M.; Ambiel, N.; Keller, A.; Wyss-Coray, T.; Kern, F.; Zuchero, J. B.

10.1101/2022.09.21.508765 — neuroscience — Posted on 2022-09-22

1291 Irregular optogenetic stimulation waveforms can induce naturalistic patterns of hippocampal spectral activity

Cole, E. R.; Eggers, T. E.; Weiss, D.; Connolly, M. J.; Gombolay, M. C.; Laxpati, N. G.; Gross, R. E.

10.1101/2022.09.21.508935 — neuroscience — Posted on 2022-09-22

1292 Thalamic regulation of a visual critical period and motor behavior

Hageter, J.; Starkey, J.; Horstick, E. J.

10.1101/2022.09.21.508908 — neuroscience — Posted on 2022-09-22

1293 Wound healing and anti-inflammatory potential of Ajuga bracteosa-conjugated silver nanoparticles in Balb/c mice

Andleeb, S.; Nazer, S.; Alomar, S. Y.; Ahmad, N.; Khan, I.; Raza, A.; Awan, U. A.; Raja, S. A.

10.1101/2022.09.21.508872 — zoology — Posted on 2022-09-22

1294 Contribution of private game ranching and captive bred operations in South Africa to white rhino Ceratotherium simum species survival conservation

Furstenburg, D.; Otto, M.; Van Niekerk, P.; Lewitton, D.

10.1101/2022.09.21.508862 — zoology — Posted on 2022-09-22

1295 Alternative proteoforms and proteoform-dependent assemblies in humans and plants

McWhite, C. D.; Sae-Lee, W.; Yuan, Y.; Mallam, A.; Gort-Frietas, N. A.; Ramundo, S.; Onishi, M.; Marcotte, E. M.

10.1101/2022.09.21.508930 — systems biology — Posted on 2022-09-22

1296 In situ single-cell analysis of canonical breast cancer biomarkers: phenotypic heterogeneity and implications on response to HER2 targeting agents.

Serna, G.; Garcia, E.; Fasani, R.; Guardia, X.; Pascual, T.; Pare, L.; Ruiz-Pace, F.; Llombart-Cussac, A.; Cortes, J.; Prat, A.; Nuciforo, P. G.

10.1101/2022.09.21.508826 — pathology — Posted on 2022-09-22

1297 Mesenchymal stem cell suppresses the efficacy of CAR-T toward killing lymphoma cells by modulating the microenvironment through stanniocalcin-1

Zhang, R.; Liu, Q.; Zhou, S.; He, H.; Zhao, M.; Ma, W.

10.1101/2022.09.21.508926 — cancer biology — Posted on 2022-09-22

1298 Spatially Resolved Transcriptomics Deconvolutes Histological Prognostic Subgroups in Patients with Colorectal Cancer and Synchronous Liver Metastases

Wood, C. S.; Pennel, K.; Leslie, H.; Legrini, A.; Cameron, A.; Melissourgou-Syka, L.; Quinn, J.; Van Wyk, H.; Hay, J.; Roseweir, A.; Nixon, C.; Roxburgh, C.; McMillan, D.; Biankin, A.; Sansom, O. J.; Horgan, P.; Edwards, J.; Steele, C.; Jamieson, N.

10.1101/2022.09.21.508569 — cancer biology — Posted on 2022-09-22

1299 FishSCT: a zebrafish-centric database for exploration and visualization of fish single-cell transcriptome

Xia, X.-Q.; Guo, C.; Ye, W.; You, D.; Zhang, W.; Cheng, Y.; Shi, M.

10.1101/2022.09.21.508858 — bioinformatics — Posted on 2022-09-22

1300 GRETA: an R package for mapping in silico genetic interaction and essentiality networks

Takemon, Y.; Marra, M. A.

10.1101/2022.09.21.508787 — bioinformatics — Posted on 2022-09-22

1301 MalariaSED: a deep learning framework to decipher the regulatory contributions of noncoding variants in malaria parasites

Wang, C.; Dong, Y.; Oberstaller, J.; Li, C.; Zhang, M.; Gibbons, J.; Pires, C. V.; Zhu, L.; Jiang, R.; Kim, K.; Miao, J.; Otto, T. D.; Cui, L.; Adams, J. H.; Liu, X.

10.1101/2022.09.21.508539 — bioinformatics — Posted on 2022-09-22

1302 Predicting Phenotypes From Novel Genomic Markers Using Deep Learning

Sehrawat, S.; Najafian, K.; Jin, L.

10.1101/2022.09.21.508954 — bioinformatics — Posted on 2022-09-22

1303 Experimental Parameters-Based Monte-Carlo Simulation of Single-Molecule Localization Microscopy of Nuclear Pore Complex to Evaluate Clustering Algorithms

Yeo, W.-H.; Zhang, Y.; Neely, A. E.; Bao, X.; Sun, C.; Zhang, H. F.

10.1101/2022.09.21.508613 — bioinformatics — Posted on 2022-09-22

1304 Efficient estimation of time-dependent functional connectivity using Structural Connectivity constraints

Hernandez, H.; Araya, D.; Gonzalez, L. L.; Roman, C.; Trujillo-Barreto, N.; Guevara, P.; El-Deredy, W.

10.1101/2022.09.21.508847 — bioinformatics — Posted on 2022-09-22

1305 Profiling emergent behaviors from single-cell motility

Maity, D.; Kamat, P.; Zamponi, N.; Jayatilaka, H.; Giri, A.; Du, W.; Johnston, A.; Starich, B.; Karl, M.; Agrawal, A.; Riley, D.; Venturitti, L.; Melnick, A.; Cerchietti, L.; Walston, J.; Phillip, J. M.

10.1101/2022.09.21.508955 — bioengineering — Posted on 2022-09-22

1306 Shape-shifting microgel automata controlled by DNA sequence instructions

Shi, R.; Chen, K.-L.; Fern, J.; Deng, S.; Liu, Y.; Scalise, D.; Huang, Q.; Cowan, N.; Gracias, D.; Schulman, R.

10.1101/2022.09.21.508918 — bioengineering — Posted on 2022-09-22

1307 Targeted Protein Degradation via Nanoparticles

Liu, Y.; Liu, R.; Dong, J.; Xia, X.; Yang, H.; Wei, S.; Fan, L.; Fang, M.; Zou, Y.; Zheng, M.; Leong, K. W.; Shi, B.

10.1101/2022.09.21.508905 — bioengineering — Posted on 2022-09-22

1308 Ribosomal protein with conserved function has entirely different structures in different organisms

Schierholz, L.; Brown, C. R.; Helena-Bueno, K.; Uversky, V. N.; Barandun, J.; Melnikov, S. V.

10.1101/2022.09.21.508910 — evolutionary biology — Posted on 2022-09-22

1309 Predicting phenotype transition probabilities via conditional algorithmic probability approximations

Dingle, K.; Novev, J. K.; Ahnert, S. E.; Louis, A. A.

10.1101/2022.09.21.508902 — evolutionary biology — Posted on 2022-09-22

1310 From southern Africa and beyond: historical biogeography of the Ledebouriinae (Scilloideae, Asparagaceae)

Howard, C. C.; Nanyeni, L.; Mollel, N.; Chuba, D.; Zuntini, A. R.; Malakasi, P.; Harvey, T. S.; Cellinese, N.

10.1101/2022.09.21.508857 — evolutionary biology — Posted on 2022-09-22

1311 Comparing multiscale, presence-only habitat suitability models created with structured survey data and community science data for a rare warbler species at the southern range margin

Whitenack, L. E.; Taylor, S. S.; Tomcho, A.; Hurlbert, A. H.

10.1101/2022.09.21.508867 — ecology — Posted on 2022-09-22

1312 Rethinking the functions of peacocks display and lek organisation in native populations of Indian Peafowl

Paranjpe, D. A.; Mahimkar, V. R.

10.1101/2022.09.21.508866 — ecology — Posted on 2022-09-22

1313 Parasite gene flow in riverine habitats: ascertaining the roles of stream drift, river bifurcations and host dispersal.

Janecka, M. J.

10.1101/2022.09.21.508869 — ecology — Posted on 2022-09-22

1314 Using occipital α-bursts to modulate behaviour in real-time

Vigue-Guix, I.; Soto-Faraco, S.

10.1101/2022.09.21.508882 — neuroscience — Posted on 2022-09-22

1315 The effect of grey wolf (Canis lupus) and human disturbance on the activity of big game species in the Bükk Hills, Hungary

Szabo, Z.; Gombköto, P.; Aranyi, S. C.; Patko, L.; Gigler, D.; Barta, Z.

10.1101/2022.09.21.508874 — zoology — Posted on 2022-09-22

1316 Crossing-over decision landscape in maize

Zelkowski, M.; Wang, M.; Sun, Q.; Pillardy, J.; Kianian, P. M.; Kianian, S.; Chen, C.; Pawlowski, W. P.

10.1101/2022.09.21.508771 — plant biology — Posted on 2022-09-22

1317 Transpiration and water use efficiency of sorghum canopies have a large genetic variability and are positively related under naturally high evaporative demand.

Pilloni, R.; Kakkera, A.; El Ghazzal, Z.; Kar, S.; Kumar, A. A.; Hajjarpoor, A.; Affortit, P.; Ribiere, W.; Kholova, J.; Tardieu, F.; Vadez, V.

10.1101/2022.09.21.508841 — physiology — Posted on 2022-09-22

1318 Mortality without springing a leak: Locust gut epithelia do not become more permeable to fluorescent dextran and bacteria in the cold

El-Saadi, M. I.; Brzezinski, K.; Hinz, A.; Phillips, L.; Wong, A.; Gerber, L.; Overgaard, J.; MacMillan, H. A.

10.1101/2022.09.21.508851 — physiology — Posted on 2022-09-22

1319 Bioefficacy of hydroxytyrosol-rich food supplements on preventing lipid peroxidation in healthy men

Bender, C.; Candi, I.; Rogel, E.

10.1101/2022.09.21.508834 — pharmacology and toxicology — Posted on 2022-09-22

1320 Rapid and sensitive single cell RNA sequencing with SHERRY2

Di, L.; Liu, B.; Lyu, Y.; Zhao, S.; Pang, Y.; Zhang, C.; Wang, J.; Qi, H.; Shen, J.; Huang, Y.

10.1101/2021.12.25.474161 — genomics — Posted on 2022-09-22

1321 Climate biogeography of Arabidopsis thaliana: linking distribution models and individual variation

Yim, C.; Bellis, E.; DeLeo, V. L.; Gamba, D.; Muscarella, R.; Lasky, J. R.

10.1101/2022.03.06.483202 — ecology — Posted on 2022-09-22

1322 Lifetime development changes in rats tracked by urinary proteome

Pan, X.; Gao, Y.

10.1101/2022.09.21.508856 — developmental biology — Posted on 2022-09-22

1323 DNA damage response signaling to mitochondria drives senescence

Yamauchi, S.; Sugiura, Y.; Yamaguchi, J.; Zhou, X.; Odawara, T.; Fukaya, S.; Naguro, I.; Uchiyama, Y.; Ichijo, H.

10.1101/2022.09.22.509001 — cell biology — Posted on 2022-09-22

1324 Development of a Novel Air-Liquid Interface Airway Tissue Equivalent Model for In Vitro Respiratory Modeling Studies

Leach, T.; Gandhi, U.; Reeves, K.; Stumpf, K.; Okuda, K.; Marini, F.; Walker, S.; Chan, J.; Cox, L. A.; Atala, A.; Murphy, S. V.

10.1101/2022.09.21.508886 — cell biology — Posted on 2022-09-22

1325 Comparative virome analysis of individual shedding routes of Miniopterus fuliginosus bats inhabiting the Wavul Galge Cave, Sri Lanka

Muzeniek, T.; Perera, T.; Siriwardana, S.; Bas, D.; Bayram, F.; Oeruc, M.; Becker-Ziaja, B.; Perera, I.; Weerasena, J.; Handunnetti, S.; Schwarz, F.; Premawansa, G.; Premawansa, S.; Yapa, W.; Nitsche, A.; Kohl, C.

10.1101/2022.09.21.508883 — molecular biology — Posted on 2022-09-22

1326 Triple COVID-19 vaccination induces humoral and cellular immunity to SARS-CoV-2 with cross-recognition of the Omicron variant and IgA secretion

Ruhl, L.; Kuehne, J. F.; Beushausen, K.; Keil, J.; Christoph, S.; Sauer, J.; Falk, C. S.

10.1101/2022.09.22.508999 — immunology — Posted on 2022-09-22

1327 SARS-CoV-2 Omicron boosting induces de novo B cell response in humans

Alsoussi, W. B.; Malladi, S. K.; Zhou, J. Q.; Liu, Z.; Ying, B.; Kim, W.; Schmitz, A. J.; Lei, T.; Horvath, S. C.; Sturtz, A. J.; McIntire, K. M.; Evavold, B.; Han, F.; Scheaffer, S. M.; Fox, I. F.; Parra-Rodriguez, L.; Nachbagauer, R.; Nestorova, B.; Chalkias, S.; Farnsworth, C. W.; Klebert, M. K.; Pusic, I.; Strnad, B. S.; Middleton, W. D.; Teefey, S. A.; Whelan, S. P. J.; Diamond, M. S.; Paris, R.; O'Halloran, J. A.; Presti, R. M.; Turner, J. S.; Ellebedy, A. H.

10.1101/2022.09.22.509040 — immunology — Posted on 2022-09-22

1328 Noncanonical inflammasome assembly requires caspase-11 catalytic activity and intra-molecular autoprocessing

Akuma, D. C.; Grubaugh, D.; Odunze, C. E.; Shin, S.; Taabazuing, C. Y.; Brodsky, I. E.

10.1101/2022.09.21.508824 — immunology — Posted on 2022-09-22

1329 Host specific sensing of coronaviruses and picornaviruses by the CARD8 inflammasome

Tsu, B. V.; Agarwal, R.; Gokhale, N. S.; Kulsuptrakul, J.; Ryan, A. P.; Castro, L. K.; Beierschmitt, C. M.; Turcotte, E. A.; Fay, E. J.; Vance, R. E.; Hyde, J. L.; Savan, R.; Mitchell, P. S.; Daugherty, M. D.

10.1101/2022.09.21.508960 — immunology — Posted on 2022-09-22

1330 Dynamic refinement of behavioral structure mediates dopamine-dependent credit assignment

Tang, J. C. Y.; Paixao, V.; Carvalho, F.; Silva, A.; Klaus, A.; Alves da Silva, J.; Costa, R. M.

10.1101/2022.09.22.507905 — neuroscience — Posted on 2022-09-22

1331 Calibration of crop phenology models: Going beyond recommendations

Wallach, D.; Palosuo, T.; Thorburn, P.; Mielenz, H.; Buis, S.; Hochman, Z.; Gourdain, E.; Garcia, C.; Andrianasolo, F.; Dumont, B.; Ferrise, R.; Gaiser, T.; Gayler, S.; Hiremath, S.; Horan, H.; Hoogenboom, G.; Jansson, P.-E.; Jing, Q.; Qian, B.; Harrison, M.; Justes, E.; Kersebaum, K.-C.; Launay, M.; Lewan, E.; Mequanint, F.; Liu, K.; Moriondo, M.; Nendel, C.; Padovan, G.; Schuetze, N.; Seserman, D.-M.; Souissi, A.; Shelia, V.; Specka, X.; Srivastava, A. K.; Trombi, G.; Weber, T.; Weihermueller, L.; Woehling, T.; Seidel, S.

10.1101/2022.06.08.495355 — plant biology — Posted on 2022-09-22

1332 Analysis of pluripotency transcription factor interactions reveals preferential binding of NANOG to SOX2 rather than NANOG or OCT4

Mistri, T. K.; Kelly, D.; Mak, J.; Colby, D.; Mullin, N.; Chambers, I.

10.1101/2020.06.24.169185 — biochemistry — Posted on 2022-09-22

1333 Evolution of new variants of SARS-COV-2 during the pandemic: mutation limited or selection limited?

Bajpai, S.; Watve, M.

10.1101/2022.09.22.509013 — evolutionary biology — Posted on 2022-09-22

1334 MATEdb, a data repository of high-quality metazoan transcriptome assemblies to accelerate phylogenomic studies

Fernandez, R.; Tonzo, V.; Simon Guerrero, C.; Lozano-Fernandez, J.; Martinez-Redondo, G. I.; Balart-Garcia, P.; Aristide, L.; Eleftheriadi, K.; Vargas-Chavez, C.

10.1101/2022.07.18.500182 — evolutionary biology — Posted on 2022-09-22

1335 Population size fluctuations can drive multitrait diversification in marine diatoms

Hinners, J.; Argyle, P. A.; Walworth, N. G.; Doblin, M. A.; Levine, N. M.; Collins, S.

10.1101/2022.04.08.487611 — evolutionary biology — Posted on 2022-09-22

1336 Patterning and growth are coordinated early in the cell cycle

Winter, C. M.; Szekely, P.; Belcher, H.; Carter, R.; Jones, M.; Fraser, S. E.; Truong, T. V.; Benfey, P. N.

10.1101/2022.09.22.508753 — developmental biology — Posted on 2022-09-22

1337 The relationship between PD-L1 and quiescence in melanocyte stem cell aging.

Palmer, J. W.; Villavicencio, K. M.; Idris, M.; Weddle, D.; Filipp, F. V.; NISC Comparative Sequencing Program - NHGRI, ; Pavan, W. J.; Harris, M. L.

10.1101/2022.09.22.508528 — cell biology — Posted on 2022-09-22

1338 Plant Polymerase IV sensitizes chromatin through histone modifications to preclude spread of silencing into protein-coding domains

Sundar, V. H.; Swetha, C.; Basu, D.; Pachamuthu, K.; Chakraborty, T.; Mosher, R.; Shivaprasad, P. V.

10.1101/2021.08.25.457601 — molecular biology — Posted on 2022-09-22

1339 Unraveling the kinetochore nanostructure in Schizosaccharomyces pombe using multi-color single-molecule localization microscopy

Virant, D.; Vojnovic, I.; Winkelmeier, J.; Endesfelder, M.; Turkowyd, B.; Lando, D.; Endesfelder, U.

10.1101/2021.12.01.469981 — microbiology — Posted on 2022-09-22

1340 In vitro evidence against productive SARS-CoV-2 infection of human testicular cells: Bystander effects of infection mediate testicular injury.

Giannakopoulos, S.; Strange, D. P.; Jiyarom, B.; Abdelaal, O.; Bradshaw, A. W.; Nerurkar, V. R.; Ward, M. A.; Bakse, J.; Yap, J.; Vanapruks, S.; Boisvert, W.; Tallquist, M.; Shikuma, C.; Sadri-Ardekani, H.; Clapp, P.; Murphy, S.; Verma, S.

10.1101/2022.09.21.508904 — microbiology — Posted on 2022-09-22

1341 Preclinical Study on SARS-CoV-2 Sublingual Vaccine with RBD Antigen and Poly(I:C) Adjuvant in Cynomolgus Macaques

Yamamoto, T.; Tanji, M.; Mitsunaga, F.; Nakamura, S.

10.1101/2022.09.21.508816 — immunology — Posted on 2022-09-22

1342 Evolution of antibody immunity following Omicron BA.1 breakthrough infection

Kaku, C. I.; Starr, T. N.; Zhou, P.; Dugan, H. L.; Khalife, P.; Song, G.; Champney, E. R.; Mielcarz, D. W.; Geoghegan, J. C.; Burton, D. R.; Andrabi, R.; Bloom, J. D.; Walker, L. M.

10.1101/2022.09.21.508922 — immunology — Posted on 2022-09-22

1343 Self-produced hydrogen sulfide improves ethanol fermentation by Saccharomyces cerevisiae and other yeast species

Espinoza-Simon, E.; Moreno-Alvarez, P.; Nieto-Zaragoza, E.; Ricardez-Garcia, C.; Rios-Castro, E.; Uribe-Carvajal, S.; Torres-Quiroz, F.

10.1101/2022.08.09.503431 — biochemistry — Posted on 2022-09-22

1344 The rapid evolution of flagellar ion-selectivity in experimental populations of E. coli

Ridone, P.; Ishida, T.; Lin, A.; Humphreys, D. T.; Giannoulatou, E.; Sowa, Y.; Baker, M. A.

10.1101/2021.01.26.427765 — microbiology — Posted on 2022-09-22

1345 Empowering rare variant burden-based gene-trait association studies via optimized computational predictor choice

Kuang, D.; Li, R.; Wu, Y.; Weile, J.; Hegele, R. A.; Roth, F. P.

10.1101/2021.09.20.459182 — systems biology — Posted on 2022-09-22

1346 origamiFISH allows universal, label-free, single molecule visualization of DNA origami nanodevices across biological samples

Wang, W. X.; Douglas, T. R.; Zhang, H.; Bhattacharya, A.; Rothenbroker, M.; Jia, Z.; Muffat, J.; Li, Y.; Chou, L. Y. T.

10.1101/2022.09.19.508533 — synthetic biology — Posted on 2022-09-22

1347 Lost In The Forest

Smith, H. L.; Biggs, P. J.; French, N. P.; Smith, A. N.; Marshall, J. C.

10.1101/2022.09.12.507676 — bioinformatics — Posted on 2022-09-22

1348 Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

Davis, K. P.; Morales, Y.; McCabe, A. L.; Aldridge, B. B.; Mecsas, J. B.

10.1101/2022.09.20.508761 — microbiology — Posted on 2022-09-22

1349 3D bioengineered neural tissue generated from patient-derived iPSCs develops time-dependent phenotypes and transcriptional features of Alzheimer's disease

Lomoio, S.; Pandey, R.; Rouleau, N.; Menicacci, B.; Kim, W.; Cantley, W.; Haydon, P.; Bennett, D.; Young-Pearse, T.; Carter, G.; Kaplan, D.; Tesco, G.

10.1101/2022.07.21.501004 — neuroscience — Posted on 2022-09-22

1350 Selective Activation of the Thyroid Hormone Receptor Beta (TRβ) Induces Tumor Suppression and Increases Efficacy of Therapeutic Agents

Gillis, N. E.; Cozzens, L. M.; Wilson, E. R.; Tomczak, J. A.; Bolf, E. L.; Carr, F. E.

10.1101/2021.06.09.447689 — cancer biology — Posted on 2022-09-22

1351 Biologically informed variational autoencoders allow predictive modeling of genetic and drug induced perturbations

Doncevic, D.; Herrmann, C.

10.1101/2022.09.20.508703 — bioinformatics — Posted on 2022-09-22

1352 A unified framework of realistic in silico data generation and statistical model inference for single-cell and spatial omics

Song, D.; Wang, Q.; Yan, G.; Liu, T.; Li, J. J.

10.1101/2022.09.20.508796 — bioinformatics — Posted on 2022-09-22

1353 Best practices for single-cell histone modification analysis

Raimundo, F.; PROMPSY, P.; Vert, J.-P.; Vallot, C.

10.1101/2022.09.21.508811 — bioinformatics — Posted on 2022-09-22

1354 Predicting Peptide HLA-II Presentation Using Immunopeptidomics, Transcriptomics and Deep Multimodal Learning

ElAbd, H.; Wendorff, M.; Koudelka, T.; Hentschker, C.; Kamps, A.-K.; Priess, C.; Wienbrandt, L.; Degenhardt, F.; Steiert, T. A.; Bacher, P.; Mathur, P.; Ellinghaus, D.; Völker, U.; Tholey, A.; Lenz, T. L.; Franke, A.

10.1101/2022.09.20.508681 — bioinformatics — Posted on 2022-09-22

1355 bayroot: Bayesian sampling of HIV-1 integration dates by root-to-tip regression

Ferreira, R.-C.; Wong, E.; Poon, A. F. Y.

10.1101/2022.09.20.508733 — bioinformatics — Posted on 2022-09-22

1356 DNAPerceiver and ProteinPerceiver: deep learning models for gene and protein expression prediction from DNA and amino-acid sequences

Stefanini, M.; Lovino, M.; Cucchiara, R.; Ficarra, E.

10.1101/2022.09.21.508821 — bioinformatics — Posted on 2022-09-22

1357 Theoretical design of a space bioprocessing system to produce recombinant proteins

Soundararajan, M.; Paddock, M. B.; Dougherty, M.; Jones, H. W.; Hogan, J. A.; Donovan, F. M.; Galazka, J. M.; Settles, A. M.

10.1101/2022.09.20.508767 — bioengineering — Posted on 2022-09-22

1358 Canary in the cardiac-valve coal mine: Flow velocity and inferred shear during prosthetic valve closure -predictors of blood damage and clotting

Scotten, L. N.; Siegel, R.; Blundon, D. J.; Deutsch, M.-A.; Martin, T. R. P.; Dutton, J. W.; Kolahdouz, E. M.; Griffith, B. E.

10.1101/2022.06.23.497372 — bioengineering — Posted on 2022-09-22

1359 A Feed-forward Pathway Drives LRRK2 kinase Membrane Recruitment and Activation

Vides, E. G.; Adhikari, A.; Chiang, C. Y.; Lis, P.; Purlyte, E.; Limouse, C.; Shumate, J. L.; Lasso, E. S.; Dhekne, H. S.; Alessi, D. R.; Pfeffer, S. R.

10.1101/2022.04.25.489459 — biochemistry — Posted on 2022-09-22

1360 Evolutionary trajectory of receptor binding specificity and promiscuity of the spike protein of SARS-CoV-2

Planchais, C.; Reyes-Ruiz, A.; Lacombe, R.; Zarantonello, A.; Lecerf, M.; Revel, M.; Roumenina, L. T.; Atanasov, B. P.; Mouquet, H.; Dimitrov, J. D.

10.1101/2022.06.11.495733 — biochemistry — Posted on 2022-09-22

1361 Audiovisual cues must be predictable and win-paired to drive risky choice

Hathaway, B. A.; Kim, D. R.; Malhas, S. B. A.; Hrelja, K. M.; Kerker, L.; Hynes, T. J.; Harris, C. B. W.; Langdon, A. J.; Winstanley, C. A.

10.1101/2022.09.20.507379 — animal behavior and cognition — Posted on 2022-09-22

1362 Accelerating Minimap2 for accurate long read alignment on GPUs

Sadasivan, H.; Maric, M.; Dawson, E.; Iyer, V.; Israeli, J.; Narayanasamy, S.

10.1101/2022.03.09.483575 — genomics — Posted on 2022-09-22

1363 Distribution of potential Neanderthal signatures in modern human mitochondrial genomes

Ferreira, R. C.; Rodrigues, C. R.; Broach, J. R.; Briones, M. R.

10.1101/190363 — genomics — Posted on 2022-09-22

1364 Climate influences bill shape diversification in cavity-excavating birds

Chhaya, V.; Reddy, S.; Krishnan, A.

10.1101/2022.09.20.508664 — evolutionary biology — Posted on 2022-09-22

1365 Genetic drift promotes and recombination hinders speciation on a holey fitness landscape

Kalirad, A.; Burch, C. L.; Azevedo, R. B. R.

10.1101/2022.09.20.508707 — evolutionary biology — Posted on 2022-09-22

1366 Reading the canid skeletal story: Coxofemoral joint pathology, and suggested implications for the phylogenetic and natural history of taxa

Lawler, D. F.; Tangredi, B. P.; Widga, C. C.; Etnier, M.; Martin, T.; Kohn, L. A.

10.1101/2022.09.20.508586 — evolutionary biology — Posted on 2022-09-22

1367 Joint likelihood-free inference of the number of selected SNPs and the selection coefficient in an evolving population

Xu, Y.; Futschik, A.; Dutta, R.

10.1101/2022.09.20.508756 — evolutionary biology — Posted on 2022-09-22

1368 Anthropogenic supply of nutrients in a wildlife reserve may compromise conservation success

Abraham, A. J.; Duvall, E.; le Roux, E.; Ganswindt, A.; Clauss, M.; Doughty, C.; Webster, A.

10.1101/2022.09.20.508584 — ecology — Posted on 2022-09-22

1369 Finding the right balance of conservation effort in cultivated grasslands: A modelling study on protecting dispersers in a climatically changing and anthropogenically disturbed environment

Leins, J. A.

10.1101/2022.09.20.508676 — ecology — Posted on 2022-09-22

1370 Modelling of tuna around fish aggregating devices: the importance of ocean flow and prey

Nooteboom, P.; Scutt Phillips, J.; Kehl, C.; Nicol, S.; van Sebille, E.

10.1101/2022.09.20.508652 — ecology — Posted on 2022-09-22

1371 Does a history of co-occurrence predict plant performance, community productivity, or invasion resistance?

Agneray, A. C.; Forister, M. L.; Parchman, T. L.; Leger, E. A.

10.1101/2022.09.20.508783 — ecology — Posted on 2022-09-22

1372 Co-stimulatory molecules decide T cell fate through regulations of their invigoration and impairment

Ichikawa, K.; Ichikawa, K.

10.1101/2022.09.21.508809 — molecular biology — Posted on 2022-09-22

1373 Nipah virus Bangladesh infection elicits organ-specific innate and inflammatory responses in the marmoset model

Stevens, C. S.; Lowry, J.; Juelich, T.; Atkins, C.; Johnson, K.; Smith, J. K.; Panis, M.; Ikegame, T.; tenOever, B.; Freiberg, A. N.; Lee, B.

10.1101/2021.10.11.463955 — microbiology — Posted on 2022-09-22

1374 Implications of the 375W mutation for HIV-1 tropism and vaccine development.

Verdejo-Torres, O.; Vargas-Pavia, T.; Fatima, S.; Clapham, P. R.; Duenas-Decamp, M. J.

10.1101/2022.08.29.505747 — microbiology — Posted on 2022-09-22

1375 Genome characterization of monkeypox cases detected in India: Identification of three sub clusters among A.2 lineage

Shete, A. M.; Yadav, P. D.; Kumar, A.; Patil, S.; Patil, D. Y.; Joshi, Y.; Majumdar, T.; Relhan, V.; Sahay, R. R.; Vasu, M.; Gawande, P.; Verma, A.; Kumar, A.; Dhakad, S.; Krishnan, A. B.; Chenayil, S.; Kumar, S.; Abraham, P.

10.1101/2022.09.16.507742 — microbiology — Posted on 2022-09-22

1376 Neural activity is spatially clustered in motor and dorsal premotor cortex

Chehade, N. G.; Gharbawie, O.

10.1101/2022.09.20.508805 — neuroscience — Posted on 2022-09-22

1377 Computer Study of Metric Perturbations Impinging onCoupled Axon Tracts

Chawla, A.; Morgera, S. D.

10.1101/2022.09.20.508763 — neuroscience — Posted on 2022-09-22

1378 The logic of recurrent circuits in the primary visual cortex

Oldenburg, I. A.; Hendricks, W. D.; Handy, G.; Shamardani, K.; Bounds, H. A.; Doiron, B.; Adesnik, H.

10.1101/2022.09.20.508739 — neuroscience — Posted on 2022-09-22

1379 Generalization of contextual fear is sex-specifically affected by high salt intake

Beaver, J. N.; Weber, B. L.; Ford, M. T.; Anello, A. E.; Ruffin, K. M.; Kassis, S. K.; Gilman, L.

10.1101/2022.09.20.508397 — neuroscience — Posted on 2022-09-22

1380 Gradual relation between perceptual awareness, recognition and pupillary responses to social threat

Poyo Solanas, M.; Zhan, M.; de Gelder, B.

10.1101/2022.09.20.508721 — neuroscience — Posted on 2022-09-22

1381 To start or to discontinue the pill - changes in progestogens reflected by resting-state connectivity and positive mood

Kimmig, A.-C. S.; Friedrich, P.; Drotleff, B.; Laemmerhofer, M.; Sundstrom-Poromaa, I.; Weis, S.; Derntl, B.

10.1101/2022.09.21.508780 — neuroscience — Posted on 2022-09-22

1382 The spatio-temporal architecture of everyday manual behavior

Sili, D.; De Giorgi, C.; Pizzuti, A.; Spezialetti, M.; de Pasquale, F.; Betti, V.

10.1101/2022.09.21.508833 — neuroscience — Posted on 2022-09-22

1383 The Interaction of Context Constraints and Predictive Validity during Sentence Reading

Terporten, R.; Huizeling, E.; Heidlmayr, K.; Hagoort, P.; Kosem, A.

10.1101/2022.09.21.508808 — neuroscience — Posted on 2022-09-22

1384 Multi-omics biomarkers aid prostate cancer prognostication

Xu, Z.; Omar, M.; Benedetti, E.; Rosenthal, J.; Umeton, R.; Krumsiek, J.; Pomerantz, M.; Imada, E.; Loda, M.; Marchionni, L.

10.1101/2022.09.20.508244 — systems biology — Posted on 2022-09-22

1385 Comprehensive characterization of multi-omic landscapes between gut-microbiota metabolites and the G-protein-coupled receptors in Alzheimer's disease

Qiu, Y.; Hou, Y.; Zhou, Y.; Xu, J.; Bykova, M.; Leverenz, J. B.; Pieper, A. P.; Nussinov, R.; Caldwell, J. Z. K.; Brown, M.; Cheng, F.

10.1101/2022.09.20.508759 — systems biology — Posted on 2022-09-22

1386 Modeling Breast Cancer Proliferation, Drug Synergies, and Alternating Therapies

He, W.; Demas, D. M.; Shajahan-Haq, A. N.; Baumann, W. T.

10.1101/2022.09.20.508795 — systems biology — Posted on 2022-09-22

1387 RNA degradation heavily impacts mRNA co-expression

Garcia Blay, O.; Verhagen, P.; Martin, B.; Hansen, M. M. K.

10.1101/2022.09.21.508820 — systems biology — Posted on 2022-09-22

1388 Complete loss of RelA and SpoT homologs in Arabidopsis reveals the importance of the plastidial stringent response in the interplay between chloroplast metabolism and plant defense response

Inazu, M.; Nemoto, T.; Suzuki, S.; Ono, S.; Kanno, Y.; Seo, M.; Oikawa, A.; Masuda, S.

10.1101/2022.09.20.508797 — plant biology — Posted on 2022-09-22

1389 NF-κB-Inducing Kinase Maintains Mitochondrial Efficiency and Systemic Metabolic Homeostasis

Pflug, K. M.; Lee, D. W.; Keeney, J.; Sitcheran, R.

10.1101/2021.08.26.457753 — physiology — Posted on 2022-09-22

1390 Molecular fingerprints are not useful in large-scale search for similarly active compounds

Venkatraman, V.; Roy, A.; Gaiser, J.; Wheeler, T.

10.1101/2022.09.20.508800 — pharmacology and toxicology — Posted on 2022-09-22

1391 FDA-approved drug screening identified micafungin as an antiviral agent against bat-borne emerging zoonotic Pteropine orthoreovirus

Katta, T.; Sato, A.; Kadofusa, N.; Ishibashi, T.; Shimoda, H.; Iida, A.; Hondo, E.

10.1101/2022.09.21.508823 — pharmacology and toxicology — Posted on 2022-09-22

1392 Single cell genotypic and phenotypic analysis of measurable residual disease in acute myeloid leukemia

Robinson, T. T.; Bowman, R. L.; Persaud, S.; Liu, Y.; Gao, Q.; Zhang, J.; Sun, X.; Miles, L. A.; Cai, S. F.; Sciambi, A.; Llanso, A.; Christopher, F. A.; Goldberg, A. D.; Dogan, A.; Roshal, M.; Levine, R.; Xiao, W.

10.1101/2022.09.20.508786 — pathology — Posted on 2022-09-22

1393 Host abundance and heterogeneity in infectiousness determine extent of the environmental reservoir

Laggan, N. A.; Parise, K. L.; White, J. P.; Kaarakka, H. M.; Redell, J. A.; DePue, J. E.; Scullon, W. H.; Kath, J.; Foster, J. T.; Kilpatrick, A. M.; Langwig, K. E.; Hoyt, J. R.

10.1101/2022.09.20.508714 — ecology — Posted on 2022-09-22

1394 PLANAtools - an interactive gene expression repository for the planarian Schmidtea mediterranea

Hoffman, M.; Wurtzel, O.

10.1101/2022.09.21.508730 — developmental biology — Posted on 2022-09-22

1395 T cell-instructed inflammation drives immune checkpoint inhibitor therapy resistance

Cho, N. W.; Guldberg, S. M.; Kim, E. J.; Hiam-Galvez, K. J.; Wai, K.; Levine, L. S.; Nabet, B. Y.; DeBarge, R.; Yee, J. L.; Ashitey, N. A.; Tenvooren, I.; Spitzer, M. H.

10.1101/2022.09.20.508732 — immunology — Posted on 2022-09-22

1396 Adolescent ethanol exposure promotes mechanical allodynia and alters dopamine transmission in the nucleus accumbens shell.

Kelley, A. M.; Del Valle, E. J.; Zaman, S.; Karkhanis, A. N.

10.1101/2022.09.20.508728 — neuroscience — Posted on 2022-09-22

1397 Choice seeking is motivated by the intrinsic need for personal control

Munuera, J.; Ribes Agost, M.; Bendetowicz, D.; Kerebel, A.; Chambon, V.; Lau, B.

10.1101/2022.09.20.508669 — neuroscience — Posted on 2022-09-22

1398 Hyperthermia elevates brain temperature and improves behavioural signs in animal models of Autism spectrum disorder.

Lopez-Rodriguez, A. B.; Murray, C.; Kealy, J.; Towns, C.; Nazmi, A.; Arnold, L.; Doran, M.; Lowry, J.; Cunningham, C.

10.1101/2022.09.20.508692 — neuroscience — Posted on 2022-09-22

1399 Combined DiI and antibody labeling reveals complex dysgenesis of hippocampal spine synapses in a mouse model of Fragile X Syndrome.

Speranza, L.; Filiz, K. D.; Goebel, S.; Perrone-Capano, C.; Pulcrano, S.; Volpicelli, F.; Francesconi, A.

10.1101/2022.09.20.508741 — neuroscience — Posted on 2022-09-22

1400 VASH1/2 inhibition accelerates functional recovery of injured nerves

Gobrecht, P.; Gebel, J.; Hilla, A.; Gisselmann, G.; Fischer, D.

10.1101/2022.09.20.507919 — neuroscience — Posted on 2022-09-22

1401 Ventral striatal dopamine encodes unique properties of visual stimuli in mice

Gonzalez, L. S.; Fisher, A. A.; Cotella, E. M.; Robinson, J. E.

10.1101/2022.09.20.508670 — neuroscience — Posted on 2022-09-22

1402 Pre- and post-task resting-state differs in clinical populations

Lor, C. S.; Zhang, M.; Karner, A.; Steyrl, D.; Sladky, R.; Scharnowski, F.; Haugg, A.

10.1101/2022.09.20.508750 — neuroscience — Posted on 2022-09-22

1403 Electroencephalogram Data Collection for Student Engagement Analysis with Audio-Visual Content

Upadhyay, R.; Singh, M.; Mishra, S.; Mehta, J.; Bansal, A.; Baranwal, M.; Kumar, V.

10.1101/2022.09.20.508656 — neuroscience — Posted on 2022-09-22

1404 Odorant Mixture Separation in Drosophila Early Olfactory System

Lazar, A. A.; Liu, T.; Yeh, C.-H.; Zhou, Y.

10.1101/2022.09.20.508558 — neuroscience — Posted on 2022-09-22

1405 Kynurenine aminotransferase II inhibition promotes sleep and rescues impairments induced by neurodevelopmental insult

Milosavljevic, S.; Smith, A. K.; Wright, C. J.; Valafar, H.; Pocivavsek, A.

10.1101/2022.09.20.508758 — neuroscience — Posted on 2022-09-22

1406 Is phase-dependent stability related to phase-dependent gait robustness?

Jin, J.; Kistemaker, D.; van Dieen, J. H.; Daffertshofer, A.; Bruijn, S. M.

10.1101/2022.09.20.508663 — physiology — Posted on 2022-09-22

1407 Microstructural and mechanical insight into atherosclerotic plaques - an ex vivo DTI study to better assess plaque vulnerability

Tornifoglio, B.; Johnston, R. D.; Stone, A. J.; Kerskens, C.; Lally, C.

10.1101/2022.09.20.508689 — bioengineering — Posted on 2022-09-22

1408 Fast and Accurate Bayesian Polygenic Risk Modeling with Variational Inference

Zabad, S.; Gravel, S.; Li, Y.

10.1101/2022.05.10.491396 — genetics — Posted on 2022-09-22

1409 Ecological landscapes guide the assembly of optimal microbial communities

B. George, A.; Korolev, K. S.

10.1101/2021.12.14.472701 — ecology — Posted on 2022-09-22

1410 Dynamic Kinetic Models Capture Cell-Free Metabolism for Improved Butanol Production

Martin, J. P.; Rasor, B. J.; DeBonis, J.; Karim, A. S.; Jewett, M. C.; Tyo, K. E. J.; Broadbelt, L. J.

10.1101/2022.09.20.508127 — synthetic biology — Posted on 2022-09-22

1411 Phosphorylation sites are evolutionary checkpoints against liquid-solid transition in protein condensates

Ranganathan, S.; Dasmeh, P.; Furniss, S.; Shakhnovich, E.

10.1101/2022.09.15.508150 — biophysics — Posted on 2022-09-22

1412 Molecular determinants of dynamic protein-protein interactions in the functional cycle of the membrane protein DsbD

Stelzl, L. S.; Kritsiligkou, P.; Mehdipour, A. R.; Baldwin, A. J.; Ferguson, S. J.; Mavridou, D. A. I.; Sansom, M. S. P.; Redfield, C.

10.1101/2022.09.07.506916 — biophysics — Posted on 2022-09-22

1413 The recovery of plant community composition following passive restoration across spatial scales

Ladouceur, E.; Isbell, F.; Clark, A. T.; Harpole, W. S.; Reich, P. B.; Tilman, G. D.; Chase, J. M.

10.1101/2022.04.14.488351 — ecology — Posted on 2022-09-22

1414 Diverse strategies for tracking seasonal environmental niches at hemispheric scale

Cohen, J.; Jetz, W.

10.1101/2022.07.15.500241 — ecology — Posted on 2022-09-22

1415 Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation

Linares, R.; Arnaud, C.-A.; Effantin, G.; Darnault, C.; Epalle, N. H.; Boeri Erba, E.; Schoehn, G.; Breyton, C.

10.1101/2022.09.20.507954 — microbiology — Posted on 2022-09-22

1416 Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans

Locher, V.; Park, S.; Bunis, D.; Makredes, S.; Burt, T. D.; Fragiadakis, G. K.; Halkias, J.

10.1101/2022.09.19.508328 — immunology — Posted on 2022-09-22

1417 A whole blood approach improves speed and accuracy when measuring mitochondrial respiration in avian hematocytes

Nord, A.; Chamkha, I.; Elmer, E.

10.1101/2022.05.25.493398 — physiology — Posted on 2022-09-22

1418 Universal dynamics of biological pattern formation in spatio-temporal morphogen variations

Dalwadi, M. P.; Pearce, P.

10.1101/2022.03.18.484904 — biophysics — Posted on 2022-09-22

1419 Visual processing and collective motion-related decision-making in desert locusts

Bleichman, I.; Yadav, P.; Ayali, A.

10.1101/2022.09.19.508462 — animal behavior and cognition — Posted on 2022-09-22

1420 Multi-lingual multi-platform investigations of online trade in jaguar parts

Polisar, J.; Davies, C.; Morcatty, T.; da Silva, M.; Zhang, S.; Duchez, K.; Madrid, J.; Lambert, A. E.; Gallegos, A.; Delgado, M.; Nguyen, H.; Wallace, R.; Arias, M.; Nijman, V.; Ramnarace, J.; Pennell, R.; Novelo, Y.; Rumiz, D.; Rivero, K.; Murillo, Y.; Salas, M. N.; Kretser, H.; Reuter, A.

10.1101/2022.09.19.508455 — ecology — Posted on 2022-09-22

1421 A gradient in glucose metabolism regulates hair cell morphology along the tonotopic axis of the developing cochlea

O'Sullivan, J. D.; Blacker, T. S.; Scott, C. A.; Chang, W.; Ahmed, M.; Mann, Z. F.

10.1101/2022.04.11.487851 — developmental biology — Posted on 2022-09-22

1422 Incoherent collective cell chemotaxis in a zebrafish model of branchio-oto-renal syndrome

Lopez-Schier, H.; Hammerschmidt, M.; Kawakami, K.; Pinto Teixeira, F.; Miranda Rodriguez, J. R.; Borges, A.; Wibowo, I.

10.1101/2021.01.27.428404 — developmental biology — Posted on 2022-09-22

1423 Nanoscale structural organization and stoichiometry of the budding yeast kinetochore

Cieslinski, K.; Wu, Y.-L.; Nechyporenko, L.; Hoerner, S. J.; Conti, D.; Skruzny, M.; Ries, J.

10.1101/2021.12.01.469648 — cell biology — Posted on 2022-09-22

1424 Activating words without language: Beta and theta oscillations reflect lexical access and control processes during verbal and non-verbal object recognition tasks

Branzi, F.; Martin, C.; Biau, E.

10.1101/2022.09.21.508907 — neuroscience — Posted on 2022-09-22

1425 Fear memory in humans is consolidated over time independent of sleep

Pavlov, Y. G.; Pavlova, N. V.; Diekelmann, S.; Kotchoubey, B.

10.1101/2022.03.30.486375 — neuroscience — Posted on 2022-09-22

1426 Inhibiting presynaptic calcium channel mobility in the auditory cortex suppresses synchronized input processing

Deane, K. E.; Klymentiev, R.; Heck, J.; Mark, M. D.; Ohl, F. W.; Heine, M.; Happel, M. F. K.

10.1101/2022.03.30.486338 — neuroscience — Posted on 2022-09-22

1427 Genome-wide characterization of the common bean kinome: catalog and insights into expression patterns and genetic organization

Aono, A. H.; Pimenta, R. J. G.; Dambroz, C. M. d. S.; Costa, F. C. L.; Kuroshu, R. M.; de Souza, A. P.; Pereira, W. A.

10.1101/2022.08.05.503001 — plant biology — Posted on 2022-09-22

1428 Identification of hub genes and key pathways in pediatric Crohn's disease using next generation sequencing and bioinformatics analysis

Vastrad, B. M.; Vastrad, C. M.

10.1101/2022.07.27.501664 — bioinformatics — Posted on 2022-09-22

1429 DeepIFC: virtual fluorescent labeling of blood cells in imaging flow cytometry data with deep learning

Timonen, V. A.; Kerkela, E.; Impola, U.; Penna, L.; Partanen, J.; Kilpivaara, O.; Arvas, M.; Pitkanen, E.

10.1101/2022.08.10.503433 — bioinformatics — Posted on 2022-09-22

1430 Allelic Transcription Factor binding shape transcriptional kinetics in human cell lines

Jin, B.; Feng, H.; Bush, W.

10.1101/2022.09.21.508743 — genetics — Posted on 2022-09-22

1431 Copepod functional traits and groups show divergent biogeographies in the global ocean

Benedetti, F.; Wydler, J.; Vogt, M.

10.1101/2022.02.24.481747 — ecology — Posted on 2022-09-22

1432 The Venturia inaequalis effector repertoire is expressed in waves and is dominated by expanded families with predicted structural similarity to avirulence proteins from other plant-pathogenic fungi

Rocafort, M.; Bowen, J. K.; Hassing, B.; Cox, M. P.; McGreal, B.; de la Rosa, S.; Plummer, K. M.; Bradshaw, R. E.; Mesarich, C. H.

10.1101/2022.03.22.482717 — microbiology — Posted on 2022-09-22

1433 Identification of Ensifer meliloti genes required for survival during peat-based bioinoculant maturation by STM-seq

Lozano, M. J.; Mogro, E. G.; Salas, M. E.; Erdozain, S.; Zuber, N. E.; Becker, A.; Lagares, A.

10.1101/2022.09.19.508585 — microbiology — Posted on 2022-09-22

1434 "Um... it's really difficult to... um.. speak fluently": Neural tracking of spontaneous speech

Agmon, G.; Jaeger, M.; Tsarfaty, R.; Bleichner, M. G.; Zion Golumbic, E.

10.1101/2022.09.20.508802 — neuroscience — Posted on 2022-09-22

1435 Corticothalamic Neurons in Motor Cortex Have a Permissive Role in Motor Execution

Carmona, L. M.; Tun, L. T.; Kim, A.; Shiao, R.; Kissner, M. D.; Menon, V.; Costa, R. M.

10.1101/2022.09.20.508799 — neuroscience — Posted on 2022-09-22

1436 Thalamocortical interactions shape hierarchical neural variability during stimulus perception

Tauste Campo, A.; Zainos, A.; Alvarez, M.; Deco, G.; Romo, R.; Rossi Pool, R.

10.1101/2022.09.20.508691 — neuroscience — Posted on 2022-09-22

1437 Conserved coexpression at single cell resolution across primate brains

Suresh, H.; Crow, M.; Jorstad, N.; Hodge, R.; Lein, E.; Dobin, A.; Bakken, T.; Gillis, J.

10.1101/2022.09.20.508736 — systems biology — Posted on 2022-09-22

1438 Biosynthesis of Silver nanoparticles using Drimia indica and exploring its antibacterial profiling

Kamble, P. S.; Nimbalkar, M. S.; Patil, S. A.

10.1101/2022.07.25.501375 — plant biology — Posted on 2022-09-22

1439 Cytotoxic effect of Rotheca serrata on cancer cell lines MCF-7 and Neuroblastoma SH-SY5Y

Gadade, J. P.; Patil, S. A.

10.1101/2022.07.01.498410 — cancer biology — Posted on 2022-09-22

1440 Conserved allosteric inhibition mechanism in SLC1 transporters

Dong, Y.; Wang, J.; Garibsingh, R.-A.; Hutchinson, K.; Shi, Y.; Eisenberg, G.; Yu, X.; Schlessinger, A.; Grewer, C.

10.1101/2022.09.21.508810 — biophysics — Posted on 2022-09-22

1441 Protein language models trained on multiple sequence alignments learn phylogenetic relationships

Lupo, U.; Sgarbossa, D.; Bitbol, A.-F.

10.1101/2022.03.29.486219 — bioinformatics — Posted on 2022-09-22

1442 Integration of Gene Expression and DNA Methylation Data Across Different Experiments

Itai, Y.; Rappoport, N.; Shamir, R.

10.1101/2022.09.21.508920 — bioinformatics — Posted on 2022-09-22

1443 QTL mapping of the narrow-branch "Pendula" phenotype in Norway spruce (Picea abies L. Karst.)

Gil Munoz, F.; Bernhardsson, C.; Ranade, S. S.; Scofield, D. G.; Pulkkinen, P. O.; Ingvarsson, P. K.; Garcia-Gil, M. R.

10.1101/2022.09.19.508593 — genomics — Posted on 2022-09-22

1444 The effect of metal remediation on the virulence and antimicrobial resistance of the opportunistic pathogen Pseudomonas aeruginosa

Lear, L.; Hesse, E.; Newsome, L.; Gaze, W.; Buckling, A.; Vos, M.

10.1101/2022.09.20.508257 — ecology — Posted on 2022-09-22

1445 A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion

Mann, J. P.; Duan, X.; Alvarez-Guaita, A.; Haider, A.; Luijten, I.; Page, M.; Patel, S.; Scurria, F.; Protasoni, M.; Tabara, L. C.; Virtue, S.; O'Rahilly, S. I.; Armstrong, M.; Prudent, J.; Semple, R. K.; Savage, D. B.

10.1101/2022.09.20.508662 — cell biology — Posted on 2022-09-22

1446 Myosin II regulatory light chain phosphorylation and formin availability modulate cytokinesis upon changes in carbohydrate metabolism.

Prieto-Ruiz, F.; Gomez-Gil, E.; Martin-Garcia, R.; Perez-Diaz, A. J.; Vicente-Soler, J.; Franco, A.; Soto, T.; Perez, P.; Madrid, M.; Cansado, J.

10.1101/2022.09.20.508671 — cell biology — Posted on 2022-09-22

1447 Phase separation of +TIP-networks regulates microtubule dynamics

Miesch, J.; Wimbish, R. T.; Velluz, M.-C.; Aumeier, C.

10.1101/2021.09.13.459419 — cell biology — Posted on 2022-09-22

1448 Bacillus subtilis remains translationally active after CRISPRi-mediated replication initiation arrest

Munoz-Gutierrez, V.; Cornejo, F. A.; Schmidt, K.; Frese, C. K.; Halte, M.; Erhardt, M.; Elsholz, A. K. W.; Turgay, K.; Charpentier, E.

10.1101/2022.09.20.508806 — microbiology — Posted on 2022-09-22

1449 Antimicrobial Susceptibility Profiles of Bacteria Isolated from The Ozama River in Santo Domingo, Dominican Republic

Bonnellly, R.; Cavalcante, A. L. Q.; del Rosario Zorrilla, C.; Calderon, V. V.; Duarte, A.; Barauna, R. A.; Juca Ramos, R. T.; Rodriguez, Y.; Rodriguez de Francisco, L. E.; Maroto, L. O.; Perdomo, O. P.; Franco, E. F.

10.1101/2022.09.19.508624 — microbiology — Posted on 2022-09-22

1450 Asymmetric inheritance of centrosomes maintains stem cell properties in human neural progenitor cells

Royall, L.; Denoth-Lippuner, A.; Jessberger, S.

10.1101/2022.09.20.508710 — neuroscience — Posted on 2022-09-22

1451 FGF21 protects against hepatic lipotoxicity and macrophage activation to attenuate fibrogenesis in nonalcoholic steatohepatitis

Liu, C.; Schönke, M.; Spoorenberg, B.; Lambooij, J.; van der Zande, H.; Zhou, E.; Tushuizen, M. E.; Andreasson, A.-C.; Park, A.; Oldham, S.; Uhrbom, M.; Ahlstedt, I.; Ikeda, Y.; Wallenius, K.; Peng, X.-R.; Guigas, B.; Boon, M. R.; Wang, Y.; Rensen, P. C.

10.1101/2022.09.20.508654 — pathology — Posted on 2022-09-22

1452 Computer generation of fruit shapes from DNA sequence

Perez-Enciso, M.; Pons, C.; Granell, A.; Soler, S.; Pico, B.; Monforte, A.; Zingaretti, L. M.

10.1101/2022.09.19.508595 — bioinformatics — Posted on 2022-09-22

1453 Microtubule-mediated GLUT4 trafficking is disrupted in insulin resistant skeletal muscle

Knudsen, J. R.; Persson, K. W.; Henriquez-Olguin, C.; Li, Z.; Di Leo, N.; Raun, S. H.; Hingst, J. R.; Trouillon, R.; Wohlwend, M.; Wojtaszewski, J. F. P.; Gijs, M. A. M.; Jensen, T.

10.1101/2022.09.19.508621 — cell biology — Posted on 2022-09-22

1454 Mechanistic insights into zearalenone-accelerated colorectal cancer in mice using integrative multi-omics approaches

Lo, E. K. K.; Wang, x.; Lee, P.-K.; Wong, H.-C.; Lee, J. C.-Y.; Gallego, C. G.; Zhao, D.; El-Nezami, H.; Li, J.

10.1101/2022.09.21.508814 — cancer biology — Posted on 2022-09-21

1455 RNASeq as a tool to understand dysregulation of potential biomarkers in HNSC

Ezhuthachan, M. M.; Joshi, M.; Raval, I.; Joshi, C.; Dasgupta, A.; Majumdar, S.; A Shah, S.

10.1101/2022.09.20.508683 — cancer biology — Posted on 2022-09-21

1456 Onecut1 partially contributes to liver progenitor cell transition and acquisition of metastatic potential in hepatocellular carcinoma.

Liu, Y.; Higashitsuji, H.; Itoh, K.; Yamaguchi, K.; Umemura, A.; Itoh, Y.; Fujita, J.

10.1101/2022.09.20.508738 — cancer biology — Posted on 2022-09-21

1457 LINC02428, a liver-specific long noncoding RNA suppresses hepatocellular carcinoma progression

Zhang, Q.; Yan, L.; Chen, J.; Liu, L.

10.1101/2022.09.21.508837 — cancer biology — Posted on 2022-09-21

1458 Nanoparticle-mediated Targeting of the Fusion Gene RUNX1/ETO in t(8;21)-positive Acute Myeloid Leukaemia

Issa, H.; Swart, L.; Rasouli, M.; Ashtiani, M.; Nakjang, S.; jyotsana, n.; Schuschel, K.; Heuser, M.; Blair, H.; Heidenreich, O.

10.1101/2022.09.21.508893 — cancer biology — Posted on 2022-09-21

1459 Transcriptional immunogenomic analysis reveals distinct immunological clusters in pediatric nervous system tumours

Nabbi, A.; Beck, P.; Delaidelli, A.; Oldridge, D. A.; Sudhaman, S.; Zhu, K.; Yang, S. Y. C.; Mulder, D. T.; Bruce, J. P.; Paulson, J. N.; Raman, P.; Zhu, Y.; Resnick, A. C.; Sorensen, P. H.; Sill, M.; Brabetz, S.; Lambo, S.; Malkin, D.; Johann, P. D.; Kool, M.; Jones, D. T. W.; Pfister, S. M.; Jäger, N.; Pugh, T. J.

10.1101/2022.09.20.508719 — genomics — Posted on 2022-09-21

1460 in vivo expression vector derived from anhydrobiotic tardigrade genome enables live imaging in Eutardigrada

Tanaka, S.; Aoki, K.; Arakawa, K.

10.1101/2022.09.21.508853 — molecular biology — Posted on 2022-09-21

1461 Parallel use of pluripotent human stem cell lung and heart models provide new insights for treatment of SARS-CoV-2

Rudraraju, R.; Gartner, M. J.; Neil, J. A.; Stout, E. S.; Chen, J.; Needham, E. J.; See, M.; Mackenzie-Kludas, C.; Yang, L. Y.; Wang, M.; Pointer, H.; Karavendzas, K.; Abu-Bonsrah, D.; Drew, D.; Sun, Y. B. Y.; Tan, J. P.; Sun, G.; Salavaty, A.; Charitakis, N.; Nim, H. T.; Currie, P. D.; Tham, W.-H.; Porrello, E.; Polo, J.; Humphrey, S. J.; Ramialison, M.; Elliott, D. A.; Subbarao, K.

10.1101/2022.09.20.508614 — microbiology — Posted on 2022-09-21

1462 Cell wall carbohydrate dynamics during the differentiation of infection structures by the apple scab fungus, Venturia inaequalis

Rocafort, M.; Srivastava, V.; Bowen, J. K.; Diaz-Moreno, S. M.; Bulone, V.; Plummer, K. M.; Sutherland, P. W.; Anderson, M. A.; Bradshaw, R. E.; Mesarich, C. H.

10.1101/2022.09.21.508768 — microbiology — Posted on 2022-09-21

1463 Exposure to BA.4/BA.5 Spike glycoprotein drives pan-Omicron neutralization in vaccine-experienced humans and mice

Muik, A.; Lui, B. G.; Bacher, M.; Wallisch, A.-K.; Toker, A.; Couto, C. I. C.; Gueler, A.; Mampilli, V.; Schmitt, G. J.; Mottl, J.; Ziegenhals, T.; Fesser, S.; Reinholz, J.; Wernig, F.; Schraut, K.-G.; Hefesha, H.; Cai, H.; Yang, Q.; Walzer, K. C.; Grosser, J.; Strauss, S.; Finlayson, A.; Krueger, K.; Ozhelvaci, O.; Grikscheit, K.; Kohmer, N.; Ciesek, S.; Swanson, K. A.; Vogel, A. B.; Tuereci, O.; Sahin, U.

10.1101/2022.09.21.508818 — immunology — Posted on 2022-09-21

1464 Specific Codons Control Cellular Resources and Fitness

Love, A. M.; Nair, N. U.

10.1101/2022.09.21.508913 — synthetic biology — Posted on 2022-09-21

1465 ETV6 Deficiency and Microsatellite Enhancers Drive Transcriptional Dysregulation in B-Lymphoblastic Leukemia

Kodgule, R.; Goldman, J. W.; Monovich, A. C.; Saari, T.; Hall, C. N.; Rajesh, N.; Gupta, J.; Aguilar, A. R.; Brown, N. A.; Chiang, M. Y.; Cieslik, M. P.; Ryan, R. J. H.

10.1101/2022.09.20.508499 — cancer biology — Posted on 2022-09-21

1466 Whole-genome sequencing and single acute toxicity of heavy metal to Photobacterium kishitanii FJ21

Yin, S.; Yi, Z.; Liu, J.; Liu, G.; Fang, J.

10.1101/2022.09.20.508755 — genomics — Posted on 2022-09-21

1467 Long-read direct RNA sequencing reveals epigenetic regulation of chimeric gene-transposon transcripts in Arabidopsis thaliana

Berthelier, J.; Furci, L.; Asai, S.; Sadykova, M.; Shimazaki, T.; Shirasu, K.; Saze, H.

10.1101/2022.09.21.507229 — genetics — Posted on 2022-09-21

1468 Association of polymorphisms of IL-6 pathway genes (IL6, IL6R and IL6ST) with COVID-19 severity in an Amazonian population.

Rodrigues, F. B. B.; Sahoo, M.

10.1101/2022.09.21.508870 — genetics — Posted on 2022-09-21

1469 Cis-regulatory variation in relation to sex and sexual dimorphism in Drosophila melanogaster

Mishra, P.; Barrera, T. S.; Grieshop, K. H.; Agrawal, A. F.

10.1101/2022.09.20.508724 — evolutionary biology — Posted on 2022-09-21

1470 Hierarchical sequence-affinity landscapes shape the evolution of breadth in an anti-influenza receptor binding site antibody

Phillips, A. M.; Maurer, D. P.; Brooks, C.; Dupic, T.; Schmidt, A. G.; Desai, M. M.

10.1101/2022.09.21.508900 — evolutionary biology — Posted on 2022-09-21

1471 SRSF2 is required for mRNA splicing and spermatogenesis

Sun, Q.; Lei, W.-L.; Du, Z.; Meng, T.-G.; SU, R.; Li, Y.-Y.; Liu, W.; Sun, S.; Liu, M.-Y.; Hou, Y.; Zhang, C.-H.; yaoting, G.; Schatten, H.; Han, Z.; Liu, C.; Wang, Z.-B.; Qian, W.-P.

10.1101/2022.09.20.508723 — developmental biology — Posted on 2022-09-21

1472 Bub1 kinase acts as a signalling hub for the entire Cryptococcus neoformans spindle assembly checkpoint pathway

Leontiou, I.; Davies, T.; Clark, I.; Aktar, K.; Suresh, A. P.; Abad, M. A.; Spanos, C.; Lee, K.-T.; Bahn, Y.-S.; Jeyaprakash, A. A.; Hardwick, K. G.

10.1101/2022.09.21.508923 — cell biology — Posted on 2022-09-21

1473 Determining distinct roles of IL-1α through generation of an IL-1α knockout mouse with no defect in IL-1β expression

Malireddi, R. K. S.; Bynigeri, R.; Kancharana, B.; Sharma, B. R.; Burton, A. R.; Pelletier, S.; Kanneganti, T.-D.

10.1101/2022.09.21.508892 — cell biology — Posted on 2022-09-21

1474 Comparative virome analysis of individual shedding routes of Miniopterus fuliginosus bats inhabiting the Wavul Galge Cave, Sri Lanka

10.1101/2022.09.21.508883 — molecular biology — Posted on 2022-09-21

1475 Periplasmic coiled coil formed by assembly platform proteins PulL and PulM is critical for function of the Klebsiella type II secretion system

Li, Y.; Santos Moreno, J.; Francetic, O.

10.1101/2022.09.21.508927 — molecular biology — Posted on 2022-09-21

1476 Toroidal displacement of Klebsiella pneumoniae by Pseudomonas aeruginosa is a unique mechanism to avoid competition for iron

Pradhan, D.; Tanwar, A.; Parthasarathy, S.; Singh, V.

10.1101/2022.09.21.508880 — microbiology — Posted on 2022-09-21

1477 The chromodomain proteins, Cbx1 and Cbx2 have distinct roles in the regulation of heterochromatin and virulence in the fungal wheat pathogen, Zymoseptoria tritici.

Fraser, C. J.; Rutherford, J. C.; Rudd, J. J.; Whitehall, S. K.

10.1101/2022.09.21.508279 — microbiology — Posted on 2022-09-21

1478 From motor protein to toxin: Mutations in the zonula occludens toxin (Zot) of Vibrio cholerae phage CTXΦ suggest a loss of phage assembly function

Ma, L.; Roux, S.; Hua, X.; Wang, Y.; Loh, B.; Leptihn, S.

10.1101/2022.09.21.508815 — microbiology — Posted on 2022-09-21

1479 Characterization of Plasmodium falciparum RAP domain proteins-RAP291 and RAP070, and their association with ribosomal RNAs

Akhtar, A.; Deshmukh, A.; Panda, A.; Saini, E.; Pandey, R.; Junaid, I. T.; Onchieku, N.; Parveen, S.; Singh, S. S.; Gupta, D.; Theisen, M.; Mohmmed, A.; Malhotra, P.

10.1101/2022.09.21.508831 — microbiology — Posted on 2022-09-21

1480 Post-vaccine epidemiology of serotype 3 pneumococci identifies transformation inhibition through prophage-driven alteration of a non-coding RNA

Kwun, M. J.; Ion, A. V.; Cheng, H.-C.; D'Aeth, J. C.; Dougan, S.; Oggioni, M. R.; Goulding, D. A.; Bentley, S. D.; Croucher, N. J.

10.1101/2022.09.21.508813 — microbiology — Posted on 2022-09-21

1481 Susceptibility of Pseudomonas aeruginosa and Acinetobacter baumannii biofilms grown on denture acrylic to denture-cleaning agents and sonication

Behbehani, M.; McDonald, A.; Nair, S. P.; Green, I. M.

10.1101/2022.09.21.508680 — microbiology — Posted on 2022-09-21

1482 Cellular and molecular dynamics in the lungs of neonatal and juvenile mice in response to E. coli

McGrath-Morrow, S. A.; Venezia, J.; Ndeh, R.; Singer, B. D.; Cimbro, R.; Soloski, M.; Scott, A. L.

10.1101/2022.09.21.508849 — immunology — Posted on 2022-09-21

1483 Transcription coactivator OCA-B/Pou2af1 is necessary and sufficient to promote T cell-intrinsic CD4 memory

Sun, W.; Kim, H.; Perovanovic, J.; Hughes, E.; Du, J.; Ibarra, A.; Hale, J. S.; Williams, M. A.; Tantin, D.

10.1101/2022.09.21.508912 — immunology — Posted on 2022-09-21

1484 A hierarchy of cell death pathways confers layered resistance to shigellosis in mice

Roncaioli, J. L.; Babirye, J. P.; Chavez, R. A.; Liu, F. L.; Turcotte, E. A.; Lee, A. Y.; Lesser, C. F.; Vance, R. E.

10.1101/2022.09.21.508939 — immunology — Posted on 2022-09-21

1485 Noncanonical inflammasome assembly requires caspase-11 catalytic activity and intra-molecular autoprocessing

Akuma, D. C.; Grubaugh, D.; Odunze, C. E.; Shin, S.; Taabazuing, C. Y.; Brodsky, I. E.

10.1101/2022.09.21.508824 — immunology — Posted on 2022-09-21

1486 PepGM: A probabilistic graphical model for taxonomic inference of viral proteome samples with associated confidence scores

Holstein, T.; Kistner, F.; Martens, L.; Muth, T.

10.1101/2022.09.21.508832 — bioinformatics — Posted on 2022-09-21

1487 Prediction of RNA secondary structures in SARS-CoV-2 and comparison with contemporary predictions

Ziesel, A.; Jabbari, H.

10.1101/2022.09.20.508790 — molecular biology — Posted on 2022-09-21

1488 TaxiBGC: a Taxonomy-guided Approach for Profiling Experimentally Characterized Microbial Biosynthetic Gene Clusters and Secondary Metabolite Production Potential in Metagenomes

Gupta, V. K.; Bakshi, U.; Chang, D.; Lee, A. R.; Davis, J. M.; Chandrasekaran, S.; Jin, Y.-S.; Freeman, M. F.; Sung, J.

10.1101/2021.07.30.454505 — bioinformatics — Posted on 2022-09-21

1489 Metabolic acids impact bone mineral maturation

Li, Y.; Li, R.; Reid, D. G.; Lunn, J. T.; Muller, K. H.; Laurencin, D.; Bonhomme, C.; Ossa, E. A.; Sommerdijk, N. A. J. M.; Duer, M.

10.1101/2022.09.21.508894 — biophysics — Posted on 2022-09-21

1490 A Practical Approach for Optimizing Off-axis Telecentric Digital Holographic Microscope Design

Jin, L.; Yu, Z.; Au, A.; Yip, C. M.

10.1101/2022.07.19.500723 — biophysics — Posted on 2022-09-21

1491 Comparisons between the Hydro Distillation and the Steam Distillation in the Extraction of Volatile Compounds from and the Anti-oxidative Activity of Prunella Vulgaris

MAK, W. C. K.

10.1101/2022.07.07.499219 — biochemistry — Posted on 2022-09-21

1492 Global phylogenomic assessment of Leptoseris and Agaricia reveals substantial undescribed diversity at mesophotic depths

Gijsbers, J. C.; Englebert, N.; Prata, K. E.; Pichon, M.; Dinesen, Z.; Brunner, R.; Eyal, G.; Gonzalez-Zapata, F. L.; Kahng, S. E.; Latijnhouwers, K. R.; Muir, P.; Radice, V. Z.; Sanchez, J. A.; Vermeij, M. J.; Hoegh-Guldberg, O.; Jacobs, S. J.; Bongaerts, P.

10.1101/2022.09.12.504660 — evolutionary biology — Posted on 2022-09-21

1493 Three-dimensional chromatin re-organization during muscle stem cell aging

Yang, B. A.; Larouche, J. A.; Sabin, K. M.; Fraczek, P. M.; Parker, S. C. J.; Aguilar, C. A.

10.1101/2022.09.21.508601 — cell biology — Posted on 2022-09-21

1494 Cryo-plasma FIB/SEM volume imaging of biological specimens

Dumoux, M.; Glen, T.; Ho, E. M. L.; Perdigao, L. M. A.; Klumpe, S.; Yee, N. B. Y.; Farmer, D.; Smith, J. L. R.; Lai, P. Y. A.; Bowles, W.; Kelley, R.; Plitzko, J. M.; Wu, L.; Basham, M.; Clare, D. K.; Siebert, C. A.; Darrow, M. C.; Naismith, J. H.; Grange, M.

10.1101/2022.09.21.508877 — cell biology — Posted on 2022-09-21

1495 Structural basis of SNAPc-dependent snRNA transcription initiation by RNA polymerase II

Rengachari, S.; Schilbach, S.; Kaliyappan, T.; Gouge, J.; Zumer, K.; Schwarz, J.; Urlaub, H.; Dienemann, C.; Vannini, A.; Cramer, P.

10.1101/2022.09.21.508861 — molecular biology — Posted on 2022-09-21

1496 Emergence of plasmid-mediated RND-type efflux pump gene cluster tmexCD-toprJ in Shewanella xiamenensis in a water environment

Dao, T. D.; Takemura, T.; Kasuga, I.; Hirabayashi, A.; Nga, N. T.; Anh, P. H. Q.; Tu, N. D.; Trang, L. T.; Tran, H. H.; Shibayama, K.; Hasebe, F.; Suzuki, M.

10.1101/2022.09.15.508154 — microbiology — Posted on 2022-09-21

1497 Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection

Martin, G.; Torres, J. L.; Pholcharee, T.; Oyen, D.; Flores-Garcia, Y.; Gibson, G.; Moskovitz, R.; Beutler, N.; Jung, D. D.; Copps, J.; Lee, W.-H.; Gonzalez-Paez, G.; Emerling, D.; MacGill, R. S.; Locke, E.; King, C. R.; Zavala, F.; Wilson, I. A.; Ward, A.

10.1101/2022.09.20.508747 — immunology — Posted on 2022-09-21

1498 Nav1.1 is essential for proprioceptive signaling and motor behaviors

Espino, C. M.; Lewis, C. M.; Ortiz, S.; Dalal, M. S.; Garlapalli, S.; Wells, K. M.; O'Neil, D. A.; Wilkinson, K. A.; Griffith, T. N.

10.1101/2022.05.05.490851 — neuroscience — Posted on 2022-09-21

1499 Signatures for Viral Infection and Inflammation in the Proximal Olfactory System in Familial Alzheimer's Disease

Bubak, A. N.; Merle, L.; Niemeyer, C. S.; Baxter, D. B.; Polese, A. G.; Ramakrishnan, V.; Gomez, J.; Madrigal, L.; Villegas-Lanau, A.; Lopera, F.; Macklin, W.; Frietze, S.; Nagel, M. A.; Restrepo, D.

10.1101/2022.07.19.500641 — neuroscience — Posted on 2022-09-21

1500 The Role of Students' Situational Interest in Classroom Learning: An Empirical Study based on both Laboratory and Naturalistic Paradigms

Ye, J.; Liu, X.; Wei, J.; Zhang, Y.

10.1101/2022.09.17.508364 — neuroscience — Posted on 2022-09-21

1501 Structural characterization of human tryptophanhydroxylase 2 reveals L-Phe as the superior regulatorydomain ligand relevant for serotonin biosynthesis

Vedel, I. M.; Prestel, A.; Zhang, Z.; Skawinska, N. T.; Stark, H.; Harris, P.; Kragelund, B. B.; Peters, G. H. J.

10.1101/2022.09.20.508773 — biophysics — Posted on 2022-09-21

1502 Membrane contact site detection (MCS-DETECT) reveals dual control of rough mitochondria-ER contacts

Cardoen, B.; Vandevoorde, K. R.; GAO, G.; Alan, P.; Liu, W.; Tiliakou, E.; Vogl, A. W.; Hamarneh, G.; Nabi, I. R.

10.1101/2022.06.23.497346 — cell biology — Posted on 2022-09-21

1503 The Entorhinal-DG/CA3 Pathway in the Medial Temporal Lobe Retains Visual Working Memory of a Simple Surface Feature

Xie, W.; Cappiello, M.; Yassa, M. A.; Ester, E.; Zaghloul, K.; Zhang, W.

10.1101/2022.08.31.506098 — neuroscience — Posted on 2022-09-21

1504 Targeting a broad spectrum of KRAS-mutant cancers by hyperactivation-induced cell death

Lilja, J.; Kaivola, J.; Conway, J. R. W.; Vuorio, J.; Parkkola, H.; Roivas, P.; Varila, T.; Jacquemet, G.; Peuhu, E.; Wang, E.; Pentikäinen, U.; Posada, I. M. D.; Hamidi, H.; Najumudeen, A. K.; Sansom, O. J.; Barsukov, I. L.; Abankwa, D.; Vattulainen, I.; Salmi, M.; Ivaska, J.

10.1101/2022.09.21.508660 — cancer biology — Posted on 2022-09-21

1505 Loss of the first β-strand of human prion protein generates an aggregation-competent partially "open" form

Hosszu, L. L. P.; Sangar, D.; Batchelor, M.; Risse, E.; Hounslow, A. M.; Waltho, J. P.; Collinge, J.; Bieschke, J.

10.1101/2022.09.20.508729 — biophysics — Posted on 2022-09-21

1506 Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography

Mehrabi, P.; Sung, S.; von Stetten, D.; Prester, A.; Hatton, C. E.; Kleine-Doepke, S.; Berkes, A.; Gore, G.; Leimkohl, J.-P.; Schikora, H.; Kollewe, M.; Rohde, H.; Wilmanns, M.; Tellkamp, F.; Schulz, E. C.

10.1101/2022.09.20.508674 — biophysics — Posted on 2022-09-21

1507 Sequential Activation and Local Unfolding Control Poly(A)-Binding Protein Condensation

Chen, R.; Kahan, D.; Shangguan, J.; Sachleben, J. R.; Riback, J. A.; Drummond, D. A.; Sosnick, T.

10.1101/2022.09.21.508844 — biophysics — Posted on 2022-09-21

1508 LEAP2 is a more conserved ligand than ghrelin for fish GHSRs

Li, H.-Z.; Shao, X.-X.; Wang, Y.-F.; Liu, Y.-L.; Xu, Z.-G.; Guo, Z.-Y.

10.1101/2022.09.21.508860 — biochemistry — Posted on 2022-09-21

1509 Structural studies of cilia and flagella associated protein 410 (CFAP410) reveal its bimodular organization with an N-terminal LRR motif and a C-terminal tetrameric helical bundle

Stadler, A.; Gabriel, H. B.; Alonso-Gil, S.; Deng, X.; Crickley, R.; Korbula, K.; Huang, K.; Zagrovic, B.; Vaughan, S.; Sunter, J.; Dong, G.

10.1101/2022.09.21.508879 — biochemistry — Posted on 2022-09-21

1510 Mitochondrial protein import stress potentiates neurodegeneration in a mouse model of Parkinson disease

Coyne, L. P.; Umino, Y.; Wang, X.; Eduado, S.; Middleton, F. A.; Chen, X. J.

10.1101/2022.09.20.508793 — biochemistry — Posted on 2022-09-21

1511 Mitochondrial protein import clogging as a mechanism of disease

Coyne, L. P.; Wang, X.; Song, J.; de Jong, E.; Schneider, K.; Massa, P. T.; Middleton, F. A.; Becker, T.; Chen, X. J.

10.1101/2022.09.20.508789 — biochemistry — Posted on 2022-09-21

1512 Metamorphic proteins at the basis of human autophagy initiation and lipid transfer

Nguyen, A.; Lugarini, F.; David, C.; Hosani, P.; Knotkova, B.; Patel, A.; Parfentev, I.; Friedrich, A.; Urlaub, H.; Meinecke, M.; Stork, B.; Faesen, A.

10.1101/2022.09.21.508836 — biochemistry — Posted on 2022-09-21

1513 Autoinsertion (LAiR): rapid functional reconstitution of integral membrane proteins into lipid bilayers

Godoy-Hernandez, A.; Asseri, A. H.; Purugganan, A. J.; Jiko, C.; de Ram, C.; Lill, H.; Pabst, M.; Mitsuoka, K.; Gerle, C.; Bald, D.; McMillan, D. G. G.

10.1101/2022.09.21.508839 — biochemistry — Posted on 2022-09-21

1514 Armor reduction and pelvic girdle loss in a population of threespine stickleback (Gasterosteus aculeatus) from western Newfoundland, Canada.

Scott, R. J.; Haines, G. E.; Trask, C. A.

10.1101/2022.09.20.508658 — evolutionary biology — Posted on 2022-09-21

1515 Down-regulated GAS6 impairs synovial macrophage efferocytosis and promotes obesity-associated osteoarthritis

Yao, Z.; Qi, W.; Liu, L.; Shao, Y.; Zhang, H.; Yin, J.; Pan, H.; Guo, X.; Liu, A.; Cai, D.; Bai, X.; Zhang, H.

10.1101/2022.09.20.508661 — immunology — Posted on 2022-09-21

1516 Chemokines form complex signals during inflammation and disease that can be decoded by extracellular matrix proteoglycans

Ridley, A. J.; Ou, Y.; Karlsson, R.; Pun, N.; Birchenough, H. L.; Jowitt, T. A.; Lawless, C.; Miller, R. L.; Dyer, D. P.

10.1101/2022.09.20.508420 — immunology — Posted on 2022-09-21

1517 Synaptic scale dopamine disruption in Huntington's Disease model mice imaged with near infrared catecholamine nanosensors

Yang, S. J.; Del Bonis-O'Donnell, J. T.; Giordani, F. A.; Wang, J. W.-T.; Lui, A.; Piekarski, D.; Irrinki, A.; Schaffer, D.; Landry, M. P.

10.1101/2022.09.19.508617 — neuroscience — Posted on 2022-09-21

1518 From toxic waste to beneficial nutrient: acetate boosts Escherichia coli growth at low glycolytic flux

Millard, P.; Uttenweiler-Joseph, S.; Enjalbert, B.

10.1101/2022.09.20.506926 — systems biology — Posted on 2022-09-21

1519 Femora from an exceptionally large population of coeval ornithomimosaurs yield evidence of sexual dimorphism in extinct theropod dinosaurs

Pintore, R.; Cornette, R.; Houssaye, A.; Allain, R.

10.1101/2022.09.20.508522 — paleontology — Posted on 2022-09-21

1520 Using Packing Defects in Heterogeneous Biological Membrane as a Lens to Explore Protein Localization Propensity and Small Molecule Permeability

Tripathy, M.; Srivastava, A.

10.1101/2022.09.20.508633 — biophysics — Posted on 2022-09-21

1521 Single-cell analysis of megakaryopoiesis in peripheral CD34+ cells: insights into ETV6-related thrombocytopenia

Bigot, T. J.-R.; Gabinaud, E.; Hannouche, L.; Sbarra, V.; Andersen, E.; Bastelica, D.; Falaise, C.; Ibrahim-Kosta, M.; Loosveld, M.; Saultier, P.; Payet-Bornet, D.; Alessi, M.-C.; Potier, D.; Poggi, M.

10.1101/2022.09.20.508634 — bioinformatics — Posted on 2022-09-21

1522 Exact global alignment using A* with seed heuristic and match pruning

Groot Koerkamp, R.; Ivanov, P.

10.1101/2022.09.19.508631 — bioinformatics — Posted on 2022-09-21

1523 DNA-encoded immunoassay in picoliter drops: a minimal cell-free approach

Jackova, B.; Mottet, G.; Rudiuk, S.; Morel, M.; Baigl, D.

10.1101/2022.09.20.508493 — bioengineering — Posted on 2022-09-21

1524 Regionally enriched rare deleterious exonic variants in the UK and Ireland

Halachev, M.; Gountouna, E.; Meynert, A.; Regeneron Genetics Center, ; Tzoneva, G.; Shuldiner, A. R.; Semple, C. A.; Wilson, J. F.

10.1101/2022.09.19.508526 — genetics — Posted on 2022-09-21

1525 The genetic architecture of Arabidopsis thaliana in response to native non-pathogenic leaf bacterial species revealed by GWA mapping in field conditions

Ramirez-Sanchez, D.; Duflos, R.; Gibelin-Viala, C.; Zamar, R.; Vailleau, F.; Roux, F.

10.1101/2022.09.19.508615 — genetics — Posted on 2022-09-21

1526 DEED: A Dataset for Dream-related Emotion Research

Liu, W.; Zhang, Y.; Ma, P.; Zheng, L.; Zhou, D.; Chen, Z.; Shen, M.; Cai, Y.; Lu, Z.; Liu, Q.; Luo, J.; Wang, X.

10.1101/2022.09.19.508475 — neuroscience — Posted on 2022-09-21

1527 Posterior white matter hyperintensities are associated with reduced medial temporal lobe subregional integrity and long-term memory in older adults

Rizvi, B.; Sathishkumar, M.; Kim, S.; Marquez, F.; Granger, S. J.; Larson, M. S.; Miranda, B. A.; Hollearn, M. K.; McMillan, L.; Nan, B.; Tustison, N. J.; Lao, P. J.; Brickman, A. M.; Greenia, D.; Corrada, M. M.; Kawas, C. H.; Yassa, M. A.

10.1101/2022.09.19.508591 — neuroscience — Posted on 2022-09-21

1528 Closed-loop spinal cord stimulation is superior in restoring locomotion in rodent models of Parkinson's Disease

Rees, B.; Borda, E.; Nicolelis, M. A.; Yadav, A. P.

10.1101/2022.09.19.508432 — neuroscience — Posted on 2022-09-21

1529 Systematic analysis uncovers SYK dependency in NF1LoF melanoma cells

Abecunas, C.; Whitehead, C.; Ziemke, E.; Baumann, D. G.; Frankowski-McGregor, C.; Sebolt-Leopold, J.; Fallahi-Sichani, M.

10.1101/2022.03.06.483170 — cancer biology — Posted on 2022-09-21

1530 Liquid-liquid phase separation of intrinsically disordered FG-Nups is driven by highly-dynamic hydrophobic FG-motifs

Dekker, M.; van der Giessen, E.; Onck, P.

10.1101/2022.09.20.508740 — biophysics — Posted on 2022-09-21

1531 Under the shadow: Old-biased genes are subject to weak purifying selection at both the tissue and cell type-specific levels

Yıldız, M.; Izgi, H.; Rahimova, F.; Altıntas, U. B.; Turan, Z. G.; Somel, M.

10.1101/2022.09.21.508695 — evolutionary biology — Posted on 2022-09-21

1532 Antibiotic perseverance increases the risk of resistance development

Brandis, G.; Larsson, J.; Elf, J.

10.1101/2022.09.20.508757 — microbiology — Posted on 2022-09-21

1533 Towards the creation of Acholeplasma laidlawii driven by synthetic genomes

Nucifora, D. P.; Mehta, N. D.; Giguere, D. J.; Karas, B. J.

10.1101/2022.09.21.508766 — synthetic biology — Posted on 2022-09-21

1534 The Arabidopsis MCTP member QUIRKY regulates the formation of the STRUBBELIG receptor kinase complex

Chen, X.; Lesniewska, B.; Vaddepalli, P.; Schneitz, K.

10.1101/2022.09.20.508642 — plant biology — Posted on 2022-09-21

1535 Differential elasticity in lineage segregation of embryonic stem cells

Ritter, C.; Lejnse, N.; Farhangi Barooji, Y.; Brickman, J. M.; Doostmohammadi, A.; Oddershede, L. B.

10.1101/2022.09.21.508812 — biophysics — Posted on 2022-09-21

1536 An endosymbiont harvest: Phylogenomic analysis of Wolbachia genomes from the Darwin Tree of Life biodiversity genomics project

Vancaester, E.; Blaxter, M.

10.1101/2022.09.20.508647 — genomics — Posted on 2022-09-21

1537 Amphibian larvae benefit from a warm environment under simultaneous threat from chytridiomycosis and ranavirosis

Herczeg, D.; Holly, D.; Kasler, A.; Bokony, V.; Papp, T.; Takacs-Vago, H.; Ujszegi, J.; Hettyey, A.

10.1101/2022.09.20.508725 — evolutionary biology — Posted on 2022-09-21

1538 Asymmetrical gene flow between coastal and inland dunes in a threatened digger wasp

Batsleer, F.; Gallin, M.; Delafonteyne, M.; Dekeukeleire, D.; T'Jollyn, F.; Vantieghem, P.; Vanden Broeck, A.; Mergeay, J.; Maes, D.; Bonte, D.

10.1101/2022.09.20.508247 — ecology — Posted on 2022-09-21

1539 Genome characterization of monkeypox cases detected in India: Identification of three sub clusters among A.2 lineage

10.1101/2022.09.16.507742 — microbiology — Posted on 2022-09-21

1540 Allosteric regulation of switch-II controls K-Ras oncogenicity

Yang, M. H.; Tran, T. H.; Hunt, B.; Agnor, R.; Johnson, C. W.; Waybright, T. J.; Nowak, J. A.; Stephen, A. G.; Simanshu, D. K.; Haigis, K. M.

10.1101/2022.09.20.508702 — cancer biology — Posted on 2022-09-21

1541 Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure

Faysal, K. M. R.; Renner, N.; Marquez, C. L.; Shah, V.; Tuckwell, A. J.; Christie, M. P.; Parker, M. W.; Turville, S. G.; James, L.; Towers, G. J.; Jacques, D. A.; Boecking, T.

10.1101/2022.09.21.508807 — biophysics — Posted on 2022-09-21

1542 Staining of human skin with RGB trichrome unveils a proteoglycan-enriched zone in the hair dermal sheath

Serrano-Garrido, C.; Gaytan, F.

10.1101/2022.09.20.508648 — cell biology — Posted on 2022-09-21

1543 Functionally conserved Pkd2, mutated in autosomal dominant polycystic kidney disease, localizes to the endoplasmic reticulum and regulates cytoplasmic calcium homeostasis in fission yeast

Koyano, T.; Kume, K.; Onishi, K.; Matsuyama, M.; Fukushima, M.; Toda, T.

10.1101/2022.09.20.508804 — cell biology — Posted on 2022-09-21

1544 Multi-Dimensional Structure and Dynamics Landscape of Proteins in Mammalian Cells Revealed by In-cell NMR

Kadavath, H.; Prymaczok, N.; Eichmann, C.; Riek, R.; Gerez, J.

10.1101/2022.09.20.508803 — cell biology — Posted on 2022-09-21

1545 MR1 dependent MAIT cell activation is regulated by autophagy associated proteins

Phalora, P.; Ussher, J. E.; Hester, S.; Marchi, E.; Mak, J. Y. W.; Fairlie, D. P.; Klenerman, P.

10.1101/2022.09.20.508788 — cell biology — Posted on 2022-09-21

1546 Comprehensive identification, isolation, and culture of human breast cell types

Thi, K.; Del Toro, K.; Licon-Munoz, Y.; Sayaman, R. W.; Hines, W. C.

10.1101/2022.09.20.508726 — cell biology — Posted on 2022-09-21

1547 Exercise induces myonuclear remodelling in humans independently of age

Battey, E.; Ross, J. A.; Hoang, A.; Wilson, D. G. S.; Levy, Y.; Pollock, R. D.; Kalakoutis, M.; Pugh, J. N.; Close, G. L.; Ellison-Hughes, G. M.; Lazarus, N.; Harridge, S. D. R.; Iskratsch, T.; Ochala, J.; Stroud, M.

10.1101/2022.09.20.506578 — cell biology — Posted on 2022-09-21

1548 Peroxisome biogenesis initiated by protein phase separation

Ravindran, R.; Bacellar, I. O. L.; Castellanos-Girouard, X.; Zhang, Z.; Kisley, L.; Michnick, S. W.

10.1101/2022.09.20.508718 — cell biology — Posted on 2022-09-21

1549 Direct control of translational elongation by TAOK2β highlights altered protein synthesis as a fundamental underlying component of autism

Henis, M.; Rucker, T.; Scharrenberg, R.; Richter, M.; Baltussen, L.; Meka, D. P.; Schwanke, B.; Neelagandan, N.; Daaboul, D.; Murtaza, N.; Krisp, C.; Harder, S.; Schluter, H.; Kneussel, M.; Hermans-Borgmeyer, I.; de Wit, J.; Singh, K. K.; Duncan, K. E.; de Anda, F. C.

10.1101/2022.08.22.504812 — neuroscience — Posted on 2022-09-21

1550 On predicting heterogeneity in nanoparticle dosage

Dowling, C. V.; Cevaal, P. M.; Faria, M.; Johnston, S. T.

10.1101/2022.05.26.493665 — biophysics — Posted on 2022-09-21

1551 Single-molecule and super-resolved imaging deciphers membrane behaviour of onco-immunogenic CCR5.

Hunter, P.; Payne-Dwyer, A. L.; Shaw, M. J.; Signoret, N.; Leake, M. C.

10.1101/2022.05.19.492692 — biophysics — Posted on 2022-09-21

1552 Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior

Keys, J. T.; Cheung, B. C. H.; Wu, M.; Lammerding, J.

10.1101/2022.09.10.507419 — cell biology — Posted on 2022-09-21

1553 An Open Microfluidic Coculture Model of Fibroblasts and Eosinophils to Investigate Mechanisms of Airway Inflammation

Zeng, Y.; Su, X.; Takezawa, M. G.; Fichtinger, P. S.; Lee, U. N.; Pippin, J. W.; Shankland, S. J.; Lim, F. Y.; Denlinger, L. C.; Jarjour, N. N.; Mathur, S. K.; Sandbo, N.; Berthier, E.; Esnault, S.; Bernau, K.; Theberge, A. B.

10.1101/2022.07.11.499658 — cell biology — Posted on 2022-09-21

1554 DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production

Hartenian, E.; Mendez, A.; Didychuk, A.; Khosla, S.; Glaunsinger, B. A.

10.1101/2022.09.19.508573 — microbiology — Posted on 2022-09-21

1555 Extraordinary selection on the human X chromosome associated with archaic admixture

Skov, L.; Coll Macia, M.; Lucotte, E.; Cavassim, M. I. A.; Castellano, D.; Schierup, M.; Munch, K.

10.1101/2022.09.19.508556 — evolutionary biology — Posted on 2022-09-20

1556 A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation

Knudsen, T. E.; Hamilton, W.; Proks, M.; Lykkegaard, M.; Nielsen, A. V.; Trusina, A.; Brickman, J. M.

10.1101/2022.09.20.508291 — cell biology — Posted on 2022-09-21

1557 A neural mechanism of cognitive reserve: The case of bilingualism

Stevens, W. D.; Khan, N.; Anderson, J. A. E.; Grady, C. L.; Bialystok, E.

10.1101/2022.09.20.508678 — neuroscience — Posted on 2022-09-20

1558 Striatal dopamine integrates cost, benefit and motivation

Eshel, N.; Touponse, G. C.; Wang, A. R.; Osterman, A. K.; Shank, A. N.; Groome, A. M.; Taniguchi, L.; Pinto, D. F. C.; Tucciarone, J.; Bentzley, B. S.; Malenka, R. C.

10.1101/2022.09.20.508777 — neuroscience — Posted on 2022-09-20

1559 N6-Adenosine methylation regulates the translation of insulin mRNA

Wilinski, D.; Dus, M.

10.1101/2022.09.20.508712 — molecular biology — Posted on 2022-09-20

1560 DAXX adds a de novo H3.3K9me3 deposition pathway to the histone chaperone network

Carraro, M.; Hendriks, I. A.; Hammond, C. M.; Solis, V.; Volker-Albert, M.; Elsborg, J. D.; Weisser, M. B.; Spanos, C.; Montoya, G.; Rappsilber, J.; Imhof, A.; Nielsen, M. L.; Groth, A.

10.1101/2022.09.20.508668 — molecular biology — Posted on 2022-09-20

1561 The DNA-relaxation-dependent Off-to-On biasing of the type 1 fimbrial genetic switch requires the Fis nucleoid-associated protein.

Conway, C.; Beckett, M. C.; Dorman, C. J.

10.1101/2022.09.20.508701 — microbiology — Posted on 2022-09-20

1562 Critical role of growth medium for detecting drug interactions in Gram-negative bacteria that model in vivo responses

Davis, K. P.; Morales, Y.; Aldridge, B. B.; Mecsas, J. B.

10.1101/2022.09.20.508761 — microbiology — Posted on 2022-09-20

1563 A small molecule RIG-I agonist serves to adjuvant broad multifaceted influenza virus vaccine immunity

Hemann, E. A.; Knoll, M. L.; Wilkins, C. R.; Subra, C.; Green, R.; Garcia-Sastre, A.; Thomas, P.; Trautmann, L.; Ireton, R.; Loo, Y.-M.; Gale, M.

10.1101/2022.09.20.508779 — immunology — Posted on 2022-09-20

1564 Plasmodium infection disrupts the T follicular helper cell response to heterologous immunization

Fontana, M.; Ollmann Saphire, E.; Pepper, M.

10.1101/2022.09.20.508672 — immunology — Posted on 2022-09-20

1565 VLA-4 suppression by senescence signals regulates meningeal immunity and leptomeningeal metastasis

Li, J.; Huang, D.; Lei, B.; Huang, J.; Zhao, Q.; Su, S.; Wang, Y.

10.1101/2022.09.20.508709 — immunology — Posted on 2022-09-20

1566 Dynamic Kinetic Models Capture Cell-Free Metabolism for Improved Butanol Production

Martin, J. P.; Rasor, B. J.; DeBonis, J.; Karim, A. S.; Jewett, M. C.; Tyo, K. E. J.; Broadbelt, L. J.

10.1101/2022.09.20.508127 — synthetic biology — Posted on 2022-09-20

1567 A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells

Heacock, M. L.; Abdulaziz, E. N.; Pan, X.; Zuckerman, A. L.; Violante, S.; Yao, C.; Cross, J. R.; Cracan, V.

10.1101/2022.09.20.508785 — bioengineering — Posted on 2022-09-20

1568 SLX4 assembles nuclear condensates that compartmentalize the SUMO-RNF4 pathway and drive DNA repair.

Alghoul, E.; Paloni, M.; Takedachi, A.; Urbach, S.; Barducci, A.; Gaillard, P.-H. L.; Basbous, J.; Constantinou, A.

10.1101/2022.09.20.508711 — biochemistry — Posted on 2022-09-20

1569 Proteome-Wide Photo-Crosslinking Enables Residue-Level Visualization of Protein Interaction Networks in vivo

Faustino, A. M.; Sharma, P.; Yadav, D.; Fried, S. D.

10.1101/2022.09.20.508727 — biochemistry — Posted on 2022-09-20

1570 Population level genetic memory of prior metabolic adaptation in E. coli

Katz, S.; Grajeda-Iglesias, C.; Agranovic, B.; Ghrayeb, A.; Abramovich, I.; Hilau, S.; Gottlieb, E.; Hershberg, R.

10.1101/2022.09.20.508651 — evolutionary biology — Posted on 2022-09-20

1571 Conserved signaling pathways antagonize and synergize with co-opted doublesex to control development of novel mimetic butterfly wing patterns

VanKuren, N.; Doellman, M. M.; Sheikh, S. I.; Droguett, D. H. P.; Massardo, D.; Kronforst, M.

10.1101/2022.09.20.508752 — evolutionary biology — Posted on 2022-09-20

1572 Bacteria evolve macroscopic multicellularity via the canalization of phenotypically plastic cell clustering

Chavhan, Y.; Dey, S.; Lind, P. A.

10.1101/2022.09.20.508687 — evolutionary biology — Posted on 2022-09-20

1573 The effect of metal remediation on the virulence and antimicrobial resistance of the opportunistic pathogen Pseudomonas aeruginosa

Lear, L.; Hesse, E.; Newsome, L.; Gaze, W.; Buckling, A.; Vos, M.

10.1101/2022.09.20.508257 — ecology — Posted on 2022-09-20

1574 Small molecule inhibition of multiple RNA binding proteins underlies Musashi-2 independent phenotypes

Walters, K.; Sajek, M. P.; Issaian, A.; Baldwin, A.; Harrison, E.; Murphy, E.; Daniels, M.; Haines, J.; Hansen, K.; D'Alessandro, A.; Mukherjee, N.

10.1101/2022.09.20.508735 — molecular biology — Posted on 2022-09-20

1575 Regulation of cellular LDL uptake by PROX1 and CHD7

Serrano Zayas, C.; Holding, M. L.; Khan, T. G.; Tang, V. T.; Skidmore, J. M.; Martin, D. M.; Ginsburg, D.; Emmer, B. T.

10.1101/2022.09.20.507601 — molecular biology — Posted on 2022-09-20

1576 CDKL5 regulates p62-mediated selective autophagy and host antiviral defense

Thinwa, J. W.; Zou, Z.; Parks, E.; Sebti, S.; Hui, K.; Singh, V.; Wei, Y.; Urquhart, G.; Jewell, J. L.; Pfeiffer, J. K.; Levine, B.; Reese, T. A.; Shiloh, M. U.

10.1101/2022.09.20.508746 — microbiology — Posted on 2022-09-20

1577 Zika virus spreads through infection of lymph node-resident macrophages

Hickman, H.; Reynoso, G. V.; Gordon, D. N.; Kalia, A.; Aguilar, C. C.; Malo, C.; Aleshnick, M.; Dowd, K.; Cherry, C.; Shannon, J.; Vrba, S.; Maciejewski, S.; Asano, K.; Pierson, T.

10.1101/2022.09.20.508424 — microbiology — Posted on 2022-09-20

1578 Pseudomonas aeruginosa FpvB is a high-affinity transporter for xenosiderophores ferrichrome and ferrioxamine B

Chan, D. C. K.; Burrows, L. L.

10.1101/2022.09.20.508722 — microbiology — Posted on 2022-09-20

1579 Structural basis of bacteriophage T5 infection trigger and E. coli cell wall perforation

Linares, R.; Arnaud, C.-A.; Effantin, G.; Darnault, C.; Epalle, N. H.; Boeri Erba, E.; Schoehn, G.; Breyton, C.

10.1101/2022.09.20.507954 — microbiology — Posted on 2022-09-20

1580 Fake it to break it: mimicking superinfection exclusion disrupts alphavirus infection and transmission in the yellow fever mosquito Aedes aegypti

Reitmayer, C. M.; Levitt, E.; Basu, S.; Atkinson, B.; Fragkoudis, R.; Merits, A.; Lumley, S.; Larner, W.; Diaz, A. V.; Rooney, S.; Thomas, C. J. E.; von Wyschetzki, K.; Rausalu, K.; Alphey, L.

10.1101/2022.09.20.508686 — microbiology — Posted on 2022-09-20

1581 Evaluating proteome allocation of Saccharomyces cerevisiae phenotypes with resource balance analysis

Dinh, H. V.; Maranas, C. D.

10.1101/2022.09.20.508694 — systems biology — Posted on 2022-09-20

1582 origamiFISH allows universal, label-free, single molecule visualization of DNA origami nanodevices across biological samples

Wang, W. X.; Douglas, T. R.; Zhang, H.; Bhattacharya, A.; Rothenbroker, M.; Jia, Z.; Muffat, J.; Li, Y.; Chou, L. Y. T.

10.1101/2022.09.19.508533 — synthetic biology — Posted on 2022-09-20

1583 Golden Standard: A complete standard, portable, and interoperative MoClo tool for model and non-model bacterial hosts.

Blazquez, B.; Torres-Bacete, J.; San Leon, D.; Kniewel, R.; Martinez, I.; Sordon, S.; Wilczak, A.; Salgado, S.; Huszcza, E.; Popłonski, J.; Prieto, M. A.; Nogales, J.

10.1101/2022.09.20.508659 — synthetic biology — Posted on 2022-09-20

1584 A Theoretical Model reveals RNA sequestration in Alpha Synuclein Aggregates

Rupert, J.; Monti, M.; Zacco, E.; Tartaglia, G. G.

10.1101/2022.09.20.508776 — biochemistry — Posted on 2022-09-20

1585 The dimerized pentraxin-like domain of the adhesion G protein-coupled receptor 112 (ADGRG4) suggests function in sensing mechanical forces

Kieslich, B.; Brendler, J.; Ricken, A.; Schoneberg, T.; Strater, N.

10.1101/2022.09.20.508530 — biochemistry — Posted on 2022-09-20

1586 Neuraminidase activity modulates cellular co-infection during influenza A virus multicycle growth

Guo, Z.; He, Y.; Benegal, A. N.; Vahey, M. D.

10.1101/2022.09.20.508375 — microbiology — Posted on 2022-09-20

1587 PrimedSherlock: A tool for rapid design of highly specific CRISPR-Cas12 crRNAs

Pitts, R. J.; Mann, J. G.

10.1101/2022.09.19.508610 — molecular biology — Posted on 2022-09-20

1588 Deep mutational scans for ACE2 binding, RBD expression, and antibody escape in the SARS-CoV-2 Omicron BA.1 and BA.2 receptor-binding domains

Starr, T. N.; Greaney, A. J.; Stewart, C. M.; Walls, A. C.; Hannon, W. W.; Veesler, D.; Bloom, J. D.

10.1101/2022.09.20.508745 — microbiology — Posted on 2022-09-20

1589 The effect of sociality on competitive interactions among birds

Berberi, I.; Miller, E. T.; Dakin, R.

10.1101/2022.05.09.491173 — animal behavior and cognition — Posted on 2022-09-20

1590 Directional proton conductance in bacteriorhodopsin is driven by concentration gradient, not affinity gradient

Ren, Z.

10.1101/2021.10.04.463074 — biochemistry — Posted on 2022-09-20

1591 Decoding the Neural Signatures of Valence and Arousal From Portable EEG Headset

Garg, N.; Garg, R.; Anand, A.; Baths, V.

10.1101/2021.07.23.453533 — animal behavior and cognition — Posted on 2022-09-20

1592 A benchmarking of human Y-chromosomal haplogroup classifiers from whole-genome and whole-exome sequence data

Garcia-Olivares, V.; Munoz-Barrera, A.; Rubio Rodriguez, L. A.; Jaspez, D.; Diaz de-Usera, A.; Inigo Campos, A.; Veeramah, K. R.; Alonso, S.; Thomas, M. G.; Gonzalez-Montelongo, R.; Lorenzo-Salazar, J. M.; Flores, C.

10.1101/2022.09.19.508481 — genomics — Posted on 2022-09-20

1593 TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair

Ghosh, I.; Kwon, Y.; Badamchi Shabestari, A.; Chikhale, R.; Chen, J.; Wiese, C.; Sung, P.; DeBenedetti, A.

10.1101/2022.09.19.508551 — molecular biology — Posted on 2022-09-20

1594 Molecular features underlying Pseudomonas aeruginosa persistence in human plasma

Janet-Maitre, M.; Pont, S.; Masson, F.; Sleiman, S.; Trouillon, J.; Robert-Genthon, M.; Gallet, B.; Dumestre-Perard, C.; Elsen, S.; Moriscot, C.; Bardoel, B.; Rooijakkers, S.; Cretin, F.; Attree, I.

10.1101/2021.12.21.473675 — microbiology — Posted on 2022-09-20

1595 Host genetic background is a barrier to vaccine-induced protection against infection

Lai, R.; Gong, D.; Williams, T.; Ogunsola, A. F.; Cavallo, K.; Arlehamn, C. L.; Beamer, G.; Ferris, M.; Sassetti, C. M.; Lauffenburger, D.; Behar, S.

10.1101/2022.09.19.508548 — immunology — Posted on 2022-09-20

1596 Beyond linear dynamic functional connectivity: a vine copula change point model

Xiong, X.; Cribben, I.

10.1101/2021.04.25.441254 — neuroscience — Posted on 2022-09-20

1597 Development of a new cold hardiness prediction model for grapevine using phased integration of acclimation and deacclimation responses

Kovaleski, A. P.; North, M.; Martinson, T. E.; Londo, J. P.

10.1101/2022.09.09.507298 — plant biology — Posted on 2022-09-20

1598 Sketching and sampling approaches for fast and accurate long read classification

Das, A.; Schatz, M. C.

10.1101/2021.11.04.467374 — bioinformatics — Posted on 2022-09-20

1599 Bias correction for inverse variance weighting Mendelian randomization

Mounier, N.; Kutalik, Z.

10.1101/2021.03.26.437168 — genetics — Posted on 2022-09-20

1600 Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals

Kliesmete, Z.; Wange, L. E.; Vieth, B.; Esgleas, M.; Radmer, J.; Huelsmann, M.; Geuder, J.; Richter, D.; Ohnuki, M.; Goetz, M.; Hellmann, I.; Enard, W.

10.1101/2021.02.05.429919 — evolutionary biology — Posted on 2022-09-20

1601 Development of a versatile high-throughput mutagenesis assay with multiplexed short read NGS using DNA-barcoded supF shuttle vector library amplified in non-SOS E. coli

Kawai, H.; Iwata, R.; Ebi, S.; Sugihara, R.; Masuda, S.; Fujiwara, C.; Kimura, S.; Kamiya, H.

10.1101/2022.07.19.500539 — molecular biology — Posted on 2022-09-20

1602 How to deal with toxic amino acids: the bipartite AzlCD complex exports histidine in Bacillus subtilis

Meissner, J.; Schramm, T.; Hossbach, B.; Stark, K.; Link, H.; Stulke, J.

10.1101/2022.07.07.499250 — microbiology — Posted on 2022-09-20

1603 Ralstonia solanacearum core effector RipE1 interacts and cleaves the Arabidopsis exocyst component Exo70B1

Tsakiri, D.; Kotsaridis, K.; Michalopoulou, V. A.; Kokkinidis, M.; Sarris, P. F.

10.1101/2022.08.31.506019 — microbiology — Posted on 2022-09-20

1604 A triple distinction of cerebellar function for oculomotor learning and fatigue compensation

Masselink, J.; Cheviet, A.; Pelisson, D.; Lappe, M.

10.1101/2022.06.15.496290 — neuroscience — Posted on 2022-09-20

1605 Monkey dorsolateral prefrontal cortex represents abstract visual sequences during a no-report task

Yusif Rodriguez, N. D. R.; McKim, T. H.; Basu, D.; Ahuja, A.; Desrochers, T. M.

10.1101/2022.09.19.508576 — neuroscience — Posted on 2022-09-20

1606 ShIVA, a user-friendly and interactive interface giving biologists control over their single-cell RNA-seq data.

Aussel, R.; Asif, M.; Chenag, S.; Jaeger, S.; Milpied, P.; Spinelli, L.

10.1101/2022.09.20.508636 — bioinformatics — Posted on 2022-09-20

1607 Foldseek: fast and accurate protein structure search

van Kempen, M.; Kim, S.; Tumescheit, C.; Mirdita, M.; Gilchrist, C. L. M.; Soeding, J.; Steinegger, M.

10.1101/2022.02.07.479398 — bioinformatics — Posted on 2022-09-20

1608 Emergence of persistent and sequential representations in the hippocampal-prefrontal circuitry during associative learning

Souza, B. C.; Klee, J. L.; Mazzucato, L.; Battaglia, F. P.

10.1101/2022.06.28.497926 — neuroscience — Posted on 2022-09-20

1609 Heat Hardening of a Larval Amphibian is Dependent on Acclimation Period and Temperature

Dallas, J. W.; Warne, R.

10.1101/2022.09.19.508599 — physiology — Posted on 2022-09-20

1610 Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function

Carter, E. P.; Yoneten, K. K.; Gavara, N.; Tyler, E. J.; Gauthier, V.; Murray, E.; Cameron, A.; Pearce, O. M. T.; Grose, R. P.

10.1101/2022.09.20.508645 — cancer biology — Posted on 2022-09-20

1611 Integrated microRNA and proteome analysis of cancer datasets with MoPC

Lovino, M.; Ficarra, E.; Martignetti, L.

10.1101/2022.09.20.508638 — bioinformatics — Posted on 2022-09-20

1612 High transposase abundance in the deep ocean is linked to a particle-associated lifestyle

Zhong, J.; Kyrysyuk, O.; del Rosario Herhandez, T.; Tully, B. J.; Anderson, R. E.

10.1101/2022.04.27.489810 — bioinformatics — Posted on 2022-09-20

1613 A novel mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteoclastogenic effects of breast cancer cells

Kumar, V.; Naqvi, S. M.; VERBRUGGEN, A.; McEvoy, E.; McNamara, L.

10.1101/2022.09.19.508588 — bioengineering — Posted on 2022-09-20

1614 In-depth characterization of apoptosis N-terminome reveals a link between caspase-3 cleavage and post-translational N-terminal acetylation

Hanna, R.; Rozenberg, A.; Ben-Yosef, D.; Lavy, T.; Kleifeld, O.

10.1101/2022.09.19.508487 — biochemistry — Posted on 2022-09-20

1615 Genomic variation across a clinical Cryptococcus population linked to disease outcome

Sephton-Clark, P. C. S.; Tenor, J.; Toffaletti, D.; Meyers, N.; Giamberardino, C.; Molloy, S.; Palmucci, J. R.; Chan, A.; Chikaonda, T.; Heyderman, R.; Hosseinipour, M.; Kalata, N.; Kanyama, C.; Kukacha, C.; Lupiya, D.; Mwandumba, H.; Harrison, T.; Bicanic, T.; Perfect, J. R.; Cuomo, C. A.

10.1101/2021.11.22.469645 — genomics — Posted on 2022-09-20

1616 Modeling the metabolic evolution of mixotrophic phytoplankton in response to rising ocean surface temperatures

Gonzalez, L. M.; Proulx, S. R.; Moeller, H. V.

10.1101/2022.07.21.501028 — evolutionary biology — Posted on 2022-09-20

1617 Caste- and sex-specific DNA methylation in a bumblebee is associated with codon degeneracy.

Marshall, H.; Nicholas, M. T.; van Zweden, J. S.; Wäckers, F.; Ross, L.; Wenseleers, T.; Mallon, E. B.

10.1101/2021.12.17.473163 — evolutionary biology — Posted on 2022-09-20

1618 Prosperity of the commons: Generalist mycorrhizal species dominate a mixed forest and may promote forest diversity by mediating resource sharing among trees

Rog, I.; Lewin-Epstein, O.; Livne-Luzon, S.; Hadany, L.; Klein, T.

10.1101/2022.08.01.502298 — ecology — Posted on 2022-09-20

1619 Structural equation models suggest that on-farm non-crop vegetation removal is not associated with improved food safety outcomes but is linked to impaired water quality

Weller, D. L.; Love, T.; Weller, D. E.; Murphy, C. M.; Rahm, B. G.; Wiedmann, M.

10.1101/2022.09.19.508625 — ecology — Posted on 2022-09-20

1620 Barcode-free prediction of cell lineages from scRNA-seq datasets

Eisele, A. S.; Tarbier, M.; Dormann, A. A.; Pelechano, V.; Suter, D. M.

10.1101/2022.09.20.508646 — developmental biology — Posted on 2022-09-20

1621 mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells

Kubiura-Ichimaru, M.; Penfold, C.; Kojima, K.; Dollet, C.; Yabukami, H.; Semi, K.; Takashima, Y.; Boroviak, T.; Kawaji, H.; Woltjen, K.; Minoda, A.; Sasaki, E.; Watanabe, T.

10.1101/2022.09.20.508677 — developmental biology — Posted on 2022-09-20

1622 Rad51 inhibition sensitizes non-replicating quiescent cells to UVB radiation and transcription stress

Khan, S.; Carpenter, M. A.; Kemp, M. G.

10.1101/2022.09.20.508657 — cell biology — Posted on 2022-09-20

1623 Bacterial Argonaute proteins aid cell division in the presence of topoisomerase inhibitors in Escherichia coli

Olina, A.; Agapov, A.; Yudin, D.; Kuzmenko, A.; Aravin, A. A.; Kulbachiskiy, A.

10.1101/2022.09.13.507849 — molecular biology — Posted on 2022-09-20

1624 Application of RGB trichrome staining to the study of human parasites

Gonzalez-Luna, J. D.; Gaytan, F.

10.1101/2022.09.20.508650 — microbiology — Posted on 2022-09-20

1625 A STIM dependent dopamine-insulin axis maintains the larval drive to feed and grow in Drosophila

Kasturacharya, N.; Dhall, J. K.; Hasan, G.

10.1101/2022.09.20.508641 — neuroscience — Posted on 2022-09-20

1626 Loss of estrogen unleashing neuro-inflammation increases the risk of Alzheimer's disease in women

Li, F.; Oh, I.; Kumar, S.; Eteleeb, A.; Gupta, A.; Buchser, W.; Xiong, C.; Cole, S. F.; McDade, E.; Karch, C.; Harari, O.; Payne, P. R.; Cruchaga, C.

10.1101/2022.09.19.508592 — neuroscience — Posted on 2022-09-20

1627 A multiplex platform to identify mechanisms and modulators of proteotoxicity in neurodegeneration

Resnick, S. J.; Qamar, S. S.; Sheng, J.; Huang, L. H.; Nixon-Abell, J.; Melore, S.; Chung, C. W.; Li, X.; Wang, J.; Zhang, N.; Shneider, N. A.; Kaminski, C. F.; Ruggeri, F. S.; Schierle, G. S. K.; St George-Hyslop, P.; Chavez, A.

10.1101/2022.09.19.508444 — neuroscience — Posted on 2022-09-20

1628 Stroke disconnectome decodes reading networks

Forkel, S. J.; Labache, L.; Nachev, P.; Thiebaut de Schotten, M.; Hesling, I.

10.1101/2022.03.20.485029 — neuroscience — Posted on 2022-09-20

1629 Flexing the principal gradient of the cerebral cortex to suit changing semantic task demands

Gao, Z.; Zheng, L.; Krieger-Redwood, K.; Halai, A.; Margulies, D. S.; Smallwood, J.; Jefferies, E.

10.1101/2022.05.14.491226 — neuroscience — Posted on 2022-09-20

1630 Sensory convergence and inhibitory divergence: deep dorsal horn inhibitory interneurons modulate the timing and magnitude of limb coordination during locomotion.

Ozeri-Engelhard, N.; Gradwell, M. A.; Laflamme, O. D.; Upadhyay, A.; Aoki, A.; Shrier, T.; Gandhi, M.; Gonzalez, M.; Eisdorfer, J. T.; Abbas- Zadeh, G.; Yusuf, N.; Imtiaz, Z.; Alomary, S. A.; Katz, J.; Haas, M.; Hernandez, Y.; Akay, T.; Abraira, V. E.

10.1101/2022.05.21.492933 — neuroscience — Posted on 2022-09-20

1631 Temporally resolved kinase regulatory networks control endothelial barrier integrity

Wei, L.; Dankwa, S.; Vijayan, K.; Smith, J. D.; Kaushansky, A.

10.1101/2022.09.19.508598 — systems biology — Posted on 2022-09-20

1632 Molecular and morphological analyses of the genus Episoriculus with the description of a new subgenus

Liu, Y.; Wang, X.; He, K.; Wan, T.; Liao, R.; Chen, S.; Liu, S.; Yue, B.

10.1101/2022.09.19.508619 — synthetic biology — Posted on 2022-09-20

1633 Multidimensional single-cell benchmarking of inducible promoters for precise dynamic control in budding yeast

Gligorovski, V.; Sadeghi, A.; Rahi, S. J.

10.1101/2020.08.16.253310 — synthetic biology — Posted on 2022-09-20

1634 A PDLP-NHL3 complex integrates plasmodesmal immune signaling cascades

Tee, E. E.; Johnston, M. G.; Papp, D.; Faulkner, C.

10.1101/2022.09.20.508228 — plant biology — Posted on 2022-09-20

1635 Network feature-based phenotyping of leaf venation robustly reconstructs the latent space

Iwamasa, K.; Noshita, K.

10.1101/2022.09.20.508639 — plant biology — Posted on 2022-09-20

1636 Development of an Agrobacterium-delivered codon-optimized CRISPR/Cas9 system for chickpea genome editing

GUPTA, S. K.; Vishwakarma, N. K.; Malakar, P.; Vanspati, P.; Sharma, N. K.; Chattopadhyay, D.

10.1101/2022.09.20.508560 — plant biology — Posted on 2022-09-20

1637 The incidence of candidate binding sites for β-arrestin in Drosophila neuropeptide GPCRs

Taghert, P. H.

10.1101/2022.09.19.508524 — physiology — Posted on 2022-09-20

1638 Microneurography as a Minimally Invasive Method to Assess Target Engagement During Neuromodulation

Verma, N.; Knudsen, B.; Gholston, A.; Skubal, A.; Blanz, S.; Settell, M.; Frank, J.; Trevathan, J.; Ludwig, K.

10.1101/2022.08.19.504592 — bioengineering — Posted on 2022-09-20

1639 Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination

Ebberink, E.; Fernandes, S.; Hatzopoulos, G.; Agashe, N.; Guidotti, N.; Reichart, T. M.; Reymond, L.; Velluz, M. C.; Pourroy, C.; Janke, C.; Gonczy, P.; Fierz, B.; Aumeier, C.

10.1101/2022.09.20.508649 — biochemistry — Posted on 2022-09-20

1640 Eliminating Genes for a Two Component System Increases PHB Productivity in Cupriavidus basilensis 4G11 Under PHB Suppressing, Non-Stress Conditions

Sander, K. B.; Abel, A. J.; Friedline, S.; Sharpless, W.; Skerker, J. M. B.; Deutschbauer, A.; Clark, D. S.; Arkin, A. P.

10.1101/2022.09.19.508597 — genomics — Posted on 2022-09-20

1641 Survey of activation-induced genome architecture reveals a novel enhancer of Myc

Chan, W. F.; Coughlan, H. D.; Ruhle, M.; Iannarella, N.; Alvarado, C.; Groom, J. R.; Keenan, C. R.; Kueh, A. J.; Wheatley, A. K.; Smyth, G.; Allan, R. S.; Johanson, T. M.

10.1101/2022.09.14.508046 — genetics — Posted on 2022-09-20

1642 Comparison of Mitogenomic and Mitochondrial Markers for the Phylogenetic and Evolutionary Study of Marmosets, with special focus on captive Callithrix jacchus

Fonseca, J. L.; del Rosario, R. C. H.; de Oliveira, M. A. B.; Feng, G.; Igayara, C. S.; McCarroll, S. A.; Nicola, P. A.; Pereira, L. C. M.; Rogers, J.; Roos, C.; Malukiewicz, J.

10.1101/2022.09.19.508604 — genetics — Posted on 2022-09-20

1643 Novel mitochondrial genome rearrangements including duplications and extensive heteroplasmy in Antarctic Notothenioid Fishes

Minhas, B. F.; Beck, E. A.; Cheng, C.- H. C.; Catchen, J. M.

10.1101/2022.09.19.508608 — evolutionary biology — Posted on 2022-09-20

1644 Dispersal provides trophic-level dependent insurance against a heatwave in freshwater ecosystems

Vad, C. F.; Hanny-Endredi, A.; Kratina, P.; Abonyi, A.; Mironova, E.; Murray, D. S.; Samchyshyna, L.; Tsakalakis, I.; Smeti, E.; Spatharis, S.; Tan, H.; Preiler, C.; Petrusek, A.; Bengtsson, M. M.; Ptacnik, R.

10.1101/2022.09.20.508571 — ecology — Posted on 2022-09-20

1645 Mitochondrial metabolism and body condition of naturally infected sunfish (Lepomis gibbosus)

Melancon, V.; Breton, S.; Bettinazzi, S.; Levet, M.; Binning, S. A.

10.1101/2022.09.19.508536 — ecology — Posted on 2022-09-20

1646 The Long Noncoding RNA Playrr Regulates Pitx2 Dosage and Protects Against Cardiac Arrhythmias

Chen, F. L.; Oxford, E. M.; Chou, S.-P.; Li, N.; Leach, J. P.; Perry, S. K.; Sanketi, B. D.; Cong, C.; Kupiec-Weglinski, S. A.; Dubowitz, R.; Daugherity, E.; Martin, J. F.; Danko, C. G.; Kurpios, N. A.

10.1101/2022.09.20.508562 — developmental biology — Posted on 2022-09-20

1647 TLK1-mediated RAD54 phosphorylation spatio-temporally regulates Homologous Recombination Repair

Ghosh, I.; Kwon, Y.; Badamchi Shabestari, A.; Chikhale, R.; Chen, J.; Sung, P.; DeBenedetti, A.

10.1101/2022.09.19.508551 — molecular biology — Posted on 2022-09-20

1648 Functional conservation of Anopheline linalool receptors through 100 million years of evolution

Pitts, R. J.; Huff, R. M.

10.1101/2022.09.19.508609 — molecular biology — Posted on 2022-09-20

1649 Detection of rifampicin resistance in sputum samples by PCR-ELISA

Caceres-Rey, O.; Bellido-Pantoja, R.; Pacheco-Ascencio, E.; Valencia-Torres, E.

10.1101/2022.09.19.508626 — molecular biology — Posted on 2022-09-20

1650 The Clostridioides difficile S-Layer Protein A (SlpA) serves as a general phage receptor

Royer, A. L. M.; Umansky, A. A.; Allen, M.-M.; Garneau, J. R.; Bedoya, M. O.; Kirk, J. A.; Govoni, G.; Fagan, R. P.; Soutourina, O.; Fortier, L.-C.

10.1101/2022.09.19.508581 — microbiology — Posted on 2022-09-20

1651 RNA processing/modifying enzymes play key roles in the response to thermospermine in Arabidopsis thaliana

Takahashi, T.; Tanaka, T.; Koyama, D.; Saraumi, M.; Motose, H.

10.1101/2022.09.19.508594 — plant biology — Posted on 2022-09-20

1652 Getting Smaller by Denaturation: Acid-Induced Compaction of Antibodies

Imamura, H.; Ooishi, A.; Honda, S.

10.1101/2022.09.19.508607 — biophysics — Posted on 2022-09-20

1653 Early Computational Detection of Potential High Risk SARS-CoV-2 Variants

Beguir, K.; Skwark, M. J.; Fu, Y.; Pierrot, T.; Lopez Carranza, S. N.; Laterre, A.; Kadri, I.; Korched, A.; Lowegard, A. U.; Lui, B. G.; Sanger, B.; Liu, Y.; Poran, A.; Muik, A.; Sahin, U.

10.1101/2021.12.24.474095 — bioinformatics — Posted on 2022-09-20

1654 PERSPECTIVES FOR POPULATION MANAGEMENT OF FELIDS IN INDIAN ZOOS

R, L.; Mallapur, G.; Ghosh, S.; Yadav, S. P.

10.1101/2022.09.18.508402 — zoology — Posted on 2022-09-20

1655 Meta-analysis of the public RNA-Seq data of the Western honeybee Apis mellifera to construct reference transcriptome data

Yokoi, K.; Wakamiya, T.; Bono, H.

10.1101/2022.09.07.506879 — bioinformatics — Posted on 2022-09-20

1656 Allosteric Regulation of Aptamer Affinity through Mechano-Chemical Coupling

Qu, H.; Zheng, M.; Ma, Q.; Wang, L.; Mao, Y.; Eisenstein, M.; Soh, H. T.; Zheng, L.

10.1101/2022.07.28.501929 — biochemistry — Posted on 2022-09-20

1657 Continuous Hypoxia Reduces Retinal Ganglion Cell Degeneration in a Mouse Model of Mitochondrial Optic Neuropathy

Warwick, A. M.; Bomze, H. M.; Wang, L.; Klingeborn, M.; Hao, Y.; Stinnett, S.; Gospe, S.

10.1101/2022.09.15.508111 — pathology — Posted on 2022-09-20

1658 APOE ε4 gene dose effect on imaging and blood biomarkers of glial reactivity and β-amyloid pathology

Snellman, A.; Ekblad, L. L.; Tuisku, J.; Koivumäki, M.; Ashton, N. J.; Lantero-Rodriguez, J.; Karikari, T. K.; Helin, S.; Bucci, M.; Löyttyniemi, E.; Parkkola, R.; Karrash, M.; Schöll, M.; Zetterberg, H.; Blennow, K.; Rinne, J.

10.1101/2022.09.19.508484 — neuroscience — Posted on 2022-09-20

1659 Dysregulation of mTOR Signaling Mediates Common Neurite and Migration Defects in Both Idiopathic and 16p11.2 Deletion Autism Neural Precursor Cells

Prem, S.; Dev, B.; Peng, C.; Mehta, M.; Alibutud, R.; Connacher, R. J.; St. Thomas, M.; Zhou, X.; Matteson, P.; Xing, J.; Millonig, J.; DiCicco-Bloom, E.

10.1101/2022.09.17.508382 — neuroscience — Posted on 2022-09-20

1660 Defining the chromatin and transcriptional landscape of stem cell-derived islets

Augsornworawat, P.; Hogrebe, N. J.; Ishahak, M.; Marquez, E.; Maestas, M. M.; Schmidt, M. D.; Veronese-Paniagua, D. A.; Gale, S. E.; Miller, J. R.; Velazco-Cruz, L.; Millman, J. R.

10.1101/2022.02.26.482126 — cell biology — Posted on 2022-09-20

1661 Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropism

Marcinkiewicz, A. L.; Brangulis, K.; Dupuis, A. P.; Hart, T. M.; Zamba_Campero, M.; Nowak, T. A.; Stout, J. L.; Akopjana, I.; Kazaks, A.; Bogans, J.; Ciota, A. T.; Kraiczy, P.; Kolokotronis, S.-O.; Lin, Y.-P.

10.1101/2022.09.13.507797 — microbiology — Posted on 2022-09-20

1662 New Perspective on GWAS: East Asian Populations from the Viewpoint of Selection Pressure and Linear Algebra with AI

Kanazawa, M.

10.1101/2022.05.27.493710 — bioinformatics — Posted on 2022-09-20

1663 Evaluation of mouse behavioral responses to nutritive versus nonnutritive sugar using a deep learning-based 3D real-time pose estimation system

Kim, J.; Kim, D.; Jung, W.; Suh, G. S. B.

10.1101/2022.09.19.508605 — animal behavior and cognition — Posted on 2022-09-19

1664 A novel mechanobiological model of bone metastasis reveals that mechanical stimulation inhibits the pro-osteoclastogenic effects of breast cancer cells

Kumar, V.; Naqvi, S. M.; VERBRUGGEN, A.; McEvoy, E.; McNamara, L.

10.1101/2022.09.19.508588 — bioengineering — Posted on 2022-09-19

1665 Accurate Detection of Proteins in Cryo-Electron Tomograms from Sparse Labels

Huang, Q.; Zhou, Y.; Liu, H.-F.; Bartesaghi, A.

10.1101/2022.09.19.508602 — biochemistry — Posted on 2022-09-19

1666 Inferring causal genes at type 2 diabetes GWAS loci through chromosome interactions in islet cells

Torres, J. M.; Sun, H.; Nylander, V.; Downes, D. J.; van de Bunt, M.; McCarthy, M. I.; Hughes, J. R.; Gloyn, A. L.

10.1101/2022.09.19.508549 — genetics — Posted on 2022-09-19

1667 Genetic incompatibilities in reciprocal hybrids between populations of Tigriopus californicus with low to moderate mitochondrial sequence divergence

Healy, T. M.; Burton, R. S.

10.1101/2022.09.19.508600 — evolutionary biology — Posted on 2022-09-19

1668 Multi-lingual multi-platform investigations of online trade in jaguar parts

10.1101/2022.09.19.508455 — ecology — Posted on 2022-09-19

1669 T cell-specific P2RX7 favors lung parenchymal CD4+ T cell accumulation in response to severe lung infections

Santiago-Carvalho, I.; Almeida-Santos, G.; Macedo, B. G.; Bomfim, C. C. B.; Almeida, F. M.; Cione, M. V. P.; Vardam-Kaur, T.; Masuda, M.; van Dijk, S.; Melo, B. M.; Nascimento, R. S. d.; Souza, R. d. C.; Peixoto-Rangel, A. L.; Coutinho-Silva, R.; Hirata, M. H.; Alves-Filho, J. C.; Alvarez, J. M.; Lassounskaia, E.; da Silva, H. B.; Lima, M. R. D.

10.1101/2022.09.19.508603 — immunology — Posted on 2022-09-19

1670 Host genetic background is a barrier to vaccine-induced protection against infection

Lai, R.; Gong, D.; Williams, T.; Ogunsola, A. F.; Cavallo, K.; Arlehamn, C. L.; Beamer, G.; Ferris, M.; Sassetti, C. M.; Lauffenburger, D.; Behar, S.

10.1101/2022.09.19.508548 — immunology — Posted on 2022-09-19

1671 Genomic effects of the glucocorticoid receptor guide the acute stress-induced delayed anxiety and basolateral amygdala spine plasticity in rats

Novaes, L. S.; Bueno-de-Camargo, L. M.; Shigeo-de-Almeida, A.; Juliano, V. A. L.; Dos Santos, N. B.; Goosens, K.; Munhoz, C. D.

10.1101/2022.09.19.508565 — neuroscience — Posted on 2022-09-19

1672 A multiplex platform to identify mechanisms and modulators of proteotoxicity in neurodegeneration

10.1101/2022.09.19.508444 — neuroscience — Posted on 2022-09-19

1673 Integrating artificial and biological neural networks to improve animal task performance using deep reinforcement learning

Li, C.; Kreiman, G.; Ramanathan, S.

10.1101/2022.09.19.508590 — neuroscience — Posted on 2022-09-19

1674 Efficacy of a Growth Hormone-Releasing Hormone Agonist in a Murine Model of Cardiometabolic Heart Failure with Preserved Ejection Fraction

Takeuchi, R. M. K.; Takeuchi, L. M.; Dulce, R. A.; Kazmierczak, K.; Balkan, W.; Cai, R.; Sha, W.; Schally, A. V.; Hare, J. M.

10.1101/2022.09.18.508429 — physiology — Posted on 2022-09-19

1675 Cryo-EM of prion strains from the same genotype of host identifies conformational determinants

Hoyt, F.; Alam, P.; Artikis, E.; Schwartz, C. L.; Hughson, A. G.; Race, B.; Baune, C.; Raymond, G. J.; Baron, G. S.; Kraus, A.; Caughey, B.

10.1101/2022.09.19.508587 — biophysics — Posted on 2022-09-19

1676 Volumetric imaging of human mesenchymal stem cells (hMSCs) for non-destructive quantification of 3D cell culture growth

Benavides, O. R.; Gibbs, H.; White, B. P.; Kaunas, R.; Gregory, C.; Maitland, K. C.

10.1101/2022.09.19.508168 — biophysics — Posted on 2022-09-19

1677 Ciliary propulsion and metachronal coordination in reef coral larvae

Poon, R. N.; Westwood, T. A.; Laeverenz-Schlogelhofer, H.; Broderick, E.; Craggs, J.; Keaveny, E. E.; Jekely, G.; Wan, K. Y.

10.1101/2022.09.19.508546 — biophysics — Posted on 2022-09-19

1678 Totem: a user-friendly tool for clustering-based inference of tree-shaped trajectories from single-cell data

Smolander, J.; Junttila, S.; Elo, L. L.

10.1101/2022.09.19.508535 — bioinformatics — Posted on 2022-09-19

1679 ELISL: Early-Late Integrated Synthetic Lethality Prediction in Cancer

Tepeli, Y.; Seale, C.; Goncalves, J. P.

10.1101/2022.09.19.508413 — bioinformatics — Posted on 2022-09-19

1680 Synthetic maize centromeres transmit chromosomes across generations

Dawe, R. K.; Gent, J. I.; Zeng, Y.; Zhang, H.; Fu, F.-F.; Wang, N.; Kim, D. W.; Swentowsky, K. W.; Liu, J.; Piri, R. D.

10.1101/2022.09.19.508542 — genetics — Posted on 2022-09-19

1681 Minimal cell JCVI-syn3B as a chassis to reveal the mechanisms behind Mycoplasma host-pathogen interactions

Bittencourt, D. M. d. C.; Brown, D. M.; Assad-Garcia, N.; Lynott, M. R.; Sun, L.; Melo, L. A. M. P. d.; Freire, M.; Glass, J. I.

10.1101/2022.09.19.508583 — microbiology — Posted on 2022-09-19

1682 Identification of Ensifer meliloti genes required for survival during peat-based bioinoculant maturation by STM-seq

Lozano, M. J.; Mogro, E. G.; Salas, M. E.; Erdozain, S.; Zuber, N. E.; Becker, A.; Lagares, A.

10.1101/2022.09.19.508585 — microbiology — Posted on 2022-09-19

1683 Mycobacterial exposure remodels alveolar macrophages and the early innate response to Mycobacterium tuberculosis infection

Mai, D.; Jahn, A.; Murray, T.; Morikubo, M.; Nemeth, J. C.; Urdahl, K. B.; Diercks, A. H.; Aderem, A.; Rothchild, A. C.

10.1101/2022.09.19.507309 — immunology — Posted on 2022-09-19

1684 Inducible CRISPR epigenome systems mimic cocaine induced bidirectional regulation of Nab2 and Egr3

Choi, E. Y.; Franco, D.; Stapf, C. A.; Gordin, M.; Chow, A.; Cover, K. K.; Chandra, R.; Lobo, M. K.

10.1101/2022.09.19.508525 — neuroscience — Posted on 2022-09-19

1685 The Vap33/Eph/Vav/Cdc42 complex confers temporal specification to the outgrowth of primary dendrites in Drosophila neurons

Kamiyama, D.; Nishida, Y.; Kamiyama, R.; Fitch, M. A.; Chihara, T.

10.1101/2022.09.19.508514 — neuroscience — Posted on 2022-09-19

1686 Widespread, perception-related information in the human brain scales with levels of consciousness

Vigotsky, A. D.; Jabakhanji, R.; Branco, P.; Iannetti, G. D.; Baliki, M. N.; Apkarian, A. V.

10.1101/2022.09.19.508437 — neuroscience — Posted on 2022-09-19

1687 Disentangling temporal and rate codes in primate somatosensory cortex

Callier, T.; Gitchell, T.; Harvey, M. A.; Bensmaia, S. J.

10.1101/2022.09.19.508566 — neuroscience — Posted on 2022-09-19

1688 A p21-GFP zebrafish model of senescence for rapid testing of senolytics in vivo.

Morsli, S.; Henriques, C.; Ellis, P. s.; Mortiboys, H. J.; Baxendale, S.; Loynes, C. A.; Renshaw, S.; Bellantuono, I.

10.1101/2022.09.19.506911 — pharmacology and toxicology — Posted on 2022-09-19

1689 Nuclear morphology and functional characteristics that enable survival of cells in the polyaneuploid cancer cell state following cytotoxic chemotherapy

Kim, C.-J.; Gonye, A. L.; Truskowski, K.; Lee, C.-F.; Pienta, K. J.; Amend, S. R.

10.1101/2022.09.19.508515 — cancer biology — Posted on 2022-09-19

1690 Importance of Molecular Dynamics Equilibrium Protocol on Protein-lipid Interactions near Channel Pore

Jiang, W.; Lacroix, J. J.; Luo, Y.

10.1101/2021.11.28.470286 — biophysics — Posted on 2022-09-19

1691 Target-template relationships in protein structure prediction and their effect on the accuracy of thermostability calculations

Oehme, D.; Lihan, M.; Lupyan, D.

10.1101/2022.09.19.508270 — biophysics — Posted on 2022-09-19

1692 CysPresso: Prediction of cysteine-dense peptide expression in mammalian cells using deep learning protein representations

Ouellet, S.; Lau, A. Z.; Ferguson, L.; Lim, T. K. Y.

10.1101/2022.09.17.508377 — bioinformatics — Posted on 2022-09-19

1693 Interpretable machine learning with tree-based Shapley additive explanations: application to metabolomics datasets for binary classification

Bifarin, O. O.

10.1101/2022.09.19.508550 — bioinformatics — Posted on 2022-09-19

1694 Aortic Shape Space Topology

Khabaz, K.; Sankary, S.; Yuan, K.; Pugar, J.; Kim, J.; Kang, J.; Nguyen, N.; Cao, K.; Pierce, N.; Lee, C. J.; Milner, R.; Kindlmann, G.; Pocivavsek, L.

10.1101/2022.09.19.508582 — bioengineering — Posted on 2022-09-19

1695 In-depth characterization of apoptosis N-terminome reveals a link between caspase-3 cleavage and post-translational N-terminal acetylation

Hanna, R.; Rozenberg, A.; Ben-Yosef, D.; Lavy, T.; Kleifeld, O.

10.1101/2022.09.19.508487 — biochemistry — Posted on 2022-09-19

1696 Genetic factors influence behavioural repeatability in juvenile poison frogs

Sonnleitner, R.; Alanen, E.; Fouilloux, C. A.; Valkonen, J.; Rojas, B.

10.1101/2022.09.19.508512 — animal behavior and cognition — Posted on 2022-09-19

1697 Analysis of polygenic selection in purebred and crossbred pig genomes using Generation Proxy Selection Mapping

Grohmann, C. J.; Shull, C. M.; Crum, T. E.; Schwab, C.; Safranski, T. J.; Decker, J. E.

10.1101/2022.09.19.508567 — genomics — Posted on 2022-09-19

1698 Annelid functional genomics reveal the origins of bilaterian life cycles

Martin-Zamora, F. M.; Liang, Y.; Guynes, K.; Carrillo-Baltodano, A.; Davies, B. E.; Donnellan, R. D.; Mortimer, K.; Tan, Y.; Moggioli, G.; Seudre, O.; Tran, M.; Luscombe, N.; Hejnol, A.; Marletaz, F.; Martin-Duran, J. M.

10.1101/2022.02.05.479245 — genomics — Posted on 2022-09-19

1699 Deciphering the genetic structure of the Quebec founder population using genealogies

Gagnon, L.; Moreau, C.; Laprise, C.; Vezina, H.; Girard, S. L.

10.1101/2022.09.19.508491 — genetics — Posted on 2022-09-19

1700 Evolutionary insights reveal a new role of PADI2 in transcriptional elongation

Villanueva-Canas, J. L.; Fernandez-Fuentes, N.; Teyssier, C.; Rogalska, M. E.; Perez, F. P.; Oliva, B.; Notredame, C.; Beato, M.; Sharma, P.

10.1101/2022.09.19.508513 — evolutionary biology — Posted on 2022-09-19

1701 Expansion and collapse of VEGF diversity in major clades of the animal kingdom

Rauniyar, K.; Bokharaie, H.; Jeltsch, M.

10.1101/2022.09.19.507521 — evolutionary biology — Posted on 2022-09-19

1702 The genomic basis of hybrid male sterility in Ficedula flycatchers

Segami Marzal, J. C.; Mugal, C. F.; Cunha, C.; Bergin, C.; Schmitz, M.; Semon, M.; Qvarnstrom, A.

10.1101/2022.09.19.508503 — evolutionary biology — Posted on 2022-09-19

1703 Influence of temperature on growth and development of dictyostelid slime moulds and its implication on the evolution of cold-tolerance

Hashimura, H.; Inouye, K.

10.1101/2022.09.19.508496 — evolutionary biology — Posted on 2022-09-19

1704 The homeobox transcription factor DUXBL controls exit from totipotency

Vega-Sendino, M.; Olbrich, T.; Stein, P.; Tillo, D.; Carey, G. I.; Savy, V.; Saykali, B.; Domingo, C. N.; Maity, T. K.; Jenkins, L. M.; Williams, C. J.; Ruiz, S.

10.1101/2022.09.19.508541 — developmental biology — Posted on 2022-09-19

1705 Notch directs telencephalic development and neuron fate determination by regulating miRNA levels

Han, J. S.; Fishman-Williams, E. K.; Decker, S. C.; Hino, K. K.; Reyes, R. V.; Brown, N. L.; Simo, S.; La Torre, A.

10.1101/2022.09.16.508220 — developmental biology — Posted on 2022-09-19

1706 Revealing the structure of somatic cell membranes by in situ cryo-electron tomography

Liu, C.; Zhou, Y.; Zou, T.; Zhao, G.; Zhang, J.; Wang, H.; Wang, H.

10.1101/2022.09.19.508494 — cell biology — Posted on 2022-09-19

1707 Multi-site phosphorylation of the TOPBP1 ATR Activation Domain propels ATR signaling during the response to DNA breaks

Senebandith, H.; Ruis, K.; Montales, K.; Jami-Alahmadi, Y.; Wohlschlegel, J.; Michael, W. M.

10.1101/2022.09.19.508511 — cell biology — Posted on 2022-09-19

1708 A PI(3,5)P2 probe reveals PIKfyve is required for Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes

Buckley, C. M.; Maib, H.; Vines, J. H.; Gueho, A.; Soldati, T.; Murray, D. H.; King, J. S.

10.1101/2022.09.19.508510 — cell biology — Posted on 2022-09-19

1709 DNA processing by the Kaposi's sarcoma-associated herpesvirus alkaline exonuclease SOX contributes to viral gene expression and infectious virion production

Hartenian, E.; Mendez, A.; Didychuk, A.; Khosla, S.; Glaunsinger, B. A.

10.1101/2022.09.19.508573 — microbiology — Posted on 2022-09-19

1710 Systems biology illuminates alternative metabolic niches in the human gut microbiome

Noecker, C.; Sanchez, J.; Bisanz, J. E.; Escalante, V.; Alexander, M.; Trepka, K.; Heinken, A.; Liu, Y.; Dodd, D.; Thiele, I.; DeFelice, B.; Turnbaugh, P. J.

10.1101/2022.09.19.508335 — microbiology — Posted on 2022-09-19

1711 Long-read powered viral metagenomics in the oligotrophic Sargasso Sea

Warwick-Dugdale, J. L.; Tian, F.; Michelsen, M. L.; Cronin, D. R.; Moore, K.; Farbos, A.; Chittick, L.; Bell, A.; Buchholz, H. H.; Parsons, R. J.; Zayed, A. A.; Allen, M. J.; Sullivan, M. B.; Temperton, B.

10.1101/2022.09.19.508504 — microbiology — Posted on 2022-09-19

1712 Homeostatic cytokines reciprocally modulate the emergence of prenatal effector PLZF+CD4+ T cells in humans

Locher, V.; Park, S.; Bunis, D.; Makredes, S.; Burt, T. D.; Fragiadakis, G. K.; Halkias, J.

10.1101/2022.09.19.508328 — immunology — Posted on 2022-09-19

1713 Influenza infection recruits distinct waves of regulatory T cells to the lung that limit lung resident IgA+ B cells

Sjaastad, L. E.; Owen, D. L.; Joo, S.; Knutson, T. P.; O'Connor, C. H.; McClusky, B.; LaRue, R. S.; Langlois, R. A.; Farrar, M. A.

10.1101/2022.09.19.508325 — immunology — Posted on 2022-09-19

1714 Sensory Tetanization to Induce LTP-Like Plasticity: A Review and Reassessment of the Approach

Dias, J. W.; McClaskey, C. M.; Rumschlag, J. A.; Harris, K. C.

10.1101/2022.03.06.483175 — neuroscience — Posted on 2022-09-19

1715 Monkey dorsolateral prefrontal cortex represents abstract visual sequences during a no-report task

Yusif Rodriguez, N. D. R.; McKim, T. H.; Basu, D.; Ahuja, A.; Desrochers, T. M.

10.1101/2022.09.19.508576 — neuroscience — Posted on 2022-09-19

1716 Expression of thioredoxin-1 in the ASJ neuron corresponds with and enhances intrinsic regenerative capacity under lesion conditioning in C. elegans

Grooms, N. W. F. W. F.; Fitzgerald, M. Q.; Schulting, L. G.; Urena, S. E.; Chung, S. H.

10.1101/2022.09.19.508543 — neuroscience — Posted on 2022-09-19

1717 Secreted long non-coding RNAs Gadlor1 and Gadlor2 affect multiple cardiac cell types and aggravate cardiac remodeling during pressure overload

Keles, M.; Grein, S.; Froese, N.; Wirth, D.; Trogisch, F. A.; Wardman, R.; Hemanna, S.; Weinzierl, N.; Uhlig, S.; Lomada, S.; Dittrich, G. M.; Szaroszyk, M.; Haustein, R.; Hegermann, J.; Martin Garrido, A.; Bauersachs, J.; Frank, D.; Frey, N.; Bieback, K.; Cordero, J.; Dobreva, G.; Wieland, T.; Heineke, J.

10.1101/2022.09.19.508486 — systems biology — Posted on 2022-09-19

1718 A lineage tree-based hidden Markov model to quantify cellular heterogeneity and plasticity

Mohammadi, F.; Visagan, S.; Gross, S. M.; Karginov, L.; Lagarde, J.; Heiser, L. M.; Meyer, A. S.

10.1101/2021.06.25.449922 — systems biology — Posted on 2022-09-19

1719 The chromosome-level genome of Water-Wisteria establishes an ecological plant model and provides insight into the molecular mechanisms underlying heterophylly in amphibious plants

Li, G.; Zhao, X.; Yang, J.; Chen, Y.; Chen, Y.; Li, Y.; Sun, Z.; Xia, M.; Wang, X.; Li, X.; Luo, K.; Hu, S.; Ponnu, J.; Kimura, S.; Hwang, I.; Torii, K. U.; Hou, H.

10.1101/2022.09.19.508473 — plant biology — Posted on 2022-09-19

1720 Plant and prokaryotic TIR domains generate distinct cyclic ADPR NADase products

Bayless, A. M.; Chen, S.; Ogden, S. C.; Xu, X.; Sidda, J. D.; Manik, M. K.; Li, S.; Kobe, B.; Ve, T.; Song, L.; Grant, M.; Wan, L.; Nishimura, M. T.

10.1101/2022.09.19.508568 — plant biology — Posted on 2022-09-19

1721 Angiogenesis precedes myogenesis during regenerationfollowing biopsy injury in skeletal muscle

Jacobsen, N. L.; Morton, A. B.; Segal, S. S.

10.1101/2022.07.23.501245 — physiology — Posted on 2022-09-19

1722 The assessment of cortical hemodynamical responses induced by tubuloglomerular feedback using in vivo imaging

Lee, B. S.; Postnov, D. D.; Sorensen, C. M.; Sosnovtseva, O.

10.1101/2022.09.19.508507 — physiology — Posted on 2022-09-19

1723 Body condition score and triglyceride concentrations and their associations with other markers of energy homeostasis in healthy, non-obese dogs

Gomez-Fernandez-Blanco, C.; Peeters, D.; Farnir, F.; Höglund, K.; Vassiliki, G.; Maria, W.; Lundgren Willesen, J.; Hanas, S.; McEntee, K.; Tiret, L.; Häggström, J.; Hannes, L.; Chetboul, V.; Fredholm, M.; Seppälä, E.; Lequarre, A.-S.; German, A. J.; Merveille, A.-C.

10.1101/2022.09.19.508523 — physiology — Posted on 2022-09-19

1724 The relaxin receptor RXFP1 signals through a mechanism of autoinhibition

Erlandson, S. C.; Rawson, S.; Osei-Owusu, J.; Brock, K. P.; Liu, X.; Paulo, J. A.; Mintseris, J.; Gygi, S. P.; Marks, D. S.; Cong, X.; Kruse, A. C.

10.1101/2022.01.22.477343 — pharmacology and toxicology — Posted on 2022-09-19

1725 In-vivo antidiarrheal activity: From the crude extract and solvent fractions of Rhamnus prinoides (Rhamnaceae) leaves

Mengie, T.; Abebe, E. C.; Muche, Z. T.; Agidew, M. M.; Yimer, Y. S.; Addis, G. T.; Baye, N. D.; Kassie, A. B.; Alemu, M. A.; Yiblet, T. G.; Tiruneh, G. A.; Dagnew, S. B.; Moges, T. A.; Tadesse, T. Y.; Zelalem, A. E.

10.1101/2022.09.19.508518 — pharmacology and toxicology — Posted on 2022-09-19

1726 Rapid-acting antidepressants ketamine and nitrous oxide converge on MAPK-DUSP signaling in the medial prefrontal cortex

Rozov, S.; Saarreharju, R. M.; Khirug, S.; Storvik, M.; Rivera, C. B.; Rantamäki, T.

10.1101/2022.09.19.508563 — pharmacology and toxicology — Posted on 2022-09-19

1727 Selective Activation of the Thyroid Hormone Receptor Beta (TRβ) Induces Tumor Suppression and Increases Efficacy of Therapeutic Agents

Gillis, N. E.; Cozzens, L. M.; Wilson, E. R.; Davidson, C. D.; Tomczak, J. A.; Bolf, E. L.; Carr, F. E.

10.1101/2021.06.09.447689 — cancer biology — Posted on 2022-09-19

1728 Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells

Liu, H.; Xu, C.; Diplas, B. H.; Brown, A.; Strickland, L. M.; Ling, J.; McLendon, R. E.; Keir, S. T.; Ashley, D. M.; He, Y.; Waitkus, M. S.

10.1101/2022.09.19.507319 — cancer biology — Posted on 2022-09-19

1729 A Bayesian Analysis of Steady-State Enzyme Data leads to Estimates of Rate Constants and Uncertainties in a Multi-Step Reaction

Barr, I.

10.1101/2021.08.04.454956 — biophysics — Posted on 2022-09-19

1730 Deciphering the alphabet of disorder -- Glu and Asp act differently on local but not global properties

Roesgaard, M. A.; Lundsgaard, J. E.; Newcombe, E. A.; Jacobsen, N. L.; Pesce, F.; Tranchant, E. E.; Lindemose, S.; Prestel, A.; Hartmann-Petersen, R.; Lindorff-Larsen, K.; Kragelund, B. B.

10.1101/2022.08.25.505250 — biophysics — Posted on 2022-09-19

1731 Organization and regulation of nuclear condensates by gene activity

Schede, H. H.; Natarajan, P.; Chakraborty, A. K.; Shrinivas, K.

10.1101/2022.09.19.508534 — biophysics — Posted on 2022-09-19

1732 A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Sub-nuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids

Keles, H.; Schofield, C. A.; Rannikmae, H.; Edwards, E. E.; Mohamet, L.

10.1101/2022.09.15.508096 — bioinformatics — Posted on 2022-09-19

1733 Graph-based algorithms for phase-type distributions

Roikjer, T.; Hobolth, A.; Munch, K.

10.1101/2022.03.12.484077 — bioinformatics — Posted on 2022-09-19

1734 saks-nf: A json solution for Nextflow pipeline construction

Zhuo, X.; Renzette, N.; Omerza, G.

10.1101/2022.09.19.508305 — bioinformatics — Posted on 2022-09-19

1735 Probabilistic 3D-modelling of genomes and genomic domains by integrating high-throughput imaging and Hi-C using machine learning

Castillo Andreo, D.; Mendieta-Esteban, J.; Marti-Renom, M. A.

10.1101/2022.09.19.508575 — bioinformatics — Posted on 2022-09-19

1736 HCR Lateral Flow Assays for Amplified Instrument-Free At-Home SARS-CoV-2 Testing

Schulte, S. J.; Huang, J.; Pierce, N. A.

10.1101/2022.09.18.508442 — bioengineering — Posted on 2022-09-19

1737 Single and Multi-trait Genomic Prediction for agronomic traits in Euterpe edulis

Canal, G. B.; Barreto, C. A. V.; de Almeida, F. A. N.; Zaidan, I. R.; do Couto, D. P.; Azevedo, C. F.; Nascimento, M.; Ferreira, M. F. d. S.; Ferreira, A.

10.1101/2022.09.19.508517 — genetics — Posted on 2022-09-19

1738 Genome-wide fixation under viability selection

Eldon, B.

10.1101/2022.09.19.508488 — evolutionary biology — Posted on 2022-09-19

1739 Artisanal and farmers bread making practices differently shape fungal species community composition in French sourdoughs

Michel, E.; Masson, E.; Bubbendorf, S.; Lapicque, L.; Nidelet, T.; Segond, D.; Guezenec, S.; Marlin, T.; Devillers, H.; Rue, O.; Onno, B.; Legrand, J.; Sicard, D.

10.1101/679472 — ecology — Posted on 2022-09-19

1740 Empirical single-cell tracking and cell-fate simulation reveal dual roles of p53 in tumor suppression

Rancourt, A.; Sato, S.; Satoh, M. S.

10.1101/319525 — cell biology — Posted on 2022-09-19

1741 The molecular mechanism of chloramphenicol and thiamphenicol resistance mediated by a novel oxidase CmO in Sphingomonadaceae

Ma, X.; Zhang, L.; Ren, Y.; Yun, H.; Cui, H.; Li, Q.; Guo, Y.; Gao, S.; Zhang, F.; Wang, A.; Liang, B.

10.1101/2022.09.18.508450 — microbiology — Posted on 2022-09-19

1742 Unlocking the hidden genetic diversity of varicosaviruses, the neglected plant rhabdoviruses

bejerman, n.; Dietzgen, R.; Debat, H. J.

10.1101/2022.09.19.508500 — microbiology — Posted on 2022-09-19

1743 Guild-level microbiome signature associated with COVID-19 severity and prognosis

Guo, M.; Wu, G.; Tan, Y.; Li, Y.; Jin, X.; Qi, W.; Guo, X.; Zhang, C.; Zhu, Z.; Zhao, L.

10.1101/2022.09.18.508418 — microbiology — Posted on 2022-09-19

1744 A Toll pathway effector protects Drosophila specifically from distinct toxins secreted by a fungus or a bacterium

Hunag, J.; Lou, Y.; Liu, J.; Bulet, P.; Jiao, R.; Hoffmann, J. A.; Liegeois, S.; Li, Z.; FERRANDON, D.

10.1101/2020.11.23.394809 — immunology — Posted on 2022-09-19

1745 A model-free approach to link neural activity to behavioral tasks

Costabile, J. D.; Balakrishnan, K. A.; Schwinn, S.; Haesemeyer, M.

10.1101/2022.08.31.506108 — neuroscience — Posted on 2022-09-19

1746 Spikebench: an open benchmark for spike train time-series classification

Lazarevich, I.; Prokin, I.; Gutkin, B.; Kazantsev, V.

10.1101/2021.03.24.436765 — neuroscience — Posted on 2022-09-19

1747 Insights from CRISPR/Cas9-mediated gene editing of centromeric histone H3 (CENH3) in carrot (Daucus carota subsp. sativus)

Dunemann, F.; Krueger, A.; Maier, K.; Struckmeyer, S.

10.1101/2022.09.19.508489 — plant biology — Posted on 2022-09-19

1748 Functional analysis of V2 protein of Beet curly top Iran virus

Bahari, A.; Castillo Garriga, A.; Safaie, N.; Bejarano, E. R.; Luna, A. P.; Shams-Bakhsh, M.

10.1101/2022.09.19.508497 — plant biology — Posted on 2022-09-19

1749 Optimal transport analysis of single-cell transcriptomics directs hypotheses prioritization and validation

Singh, R.; Li, J. S. S.; Tattikota, S. G.; Liu, Y.; Xu, J.; Hu, Y.; Perrimon, N.; Berger, B.

10.1101/2022.06.27.497786 — bioinformatics — Posted on 2022-09-19

1750 Deep Learning Architectures For the Prediction of YY1-Mediated Chromatin Loops

Abbasi, A. F.

10.1101/2022.09.19.508478 — bioinformatics — Posted on 2022-09-19

1751 Poly-omic risk scores predict inflammatory bowel disease diagnosis

Arehart, C. H.; Sterrett, J. D.; Garris, R. L.; Quispe-Pilco, R. E.; Gignoux, C. R.; Evans, L. M.; Stanislawski, M. A.

10.1101/2022.09.14.508056 — bioinformatics — Posted on 2022-09-19

1752 Coupling cellular drug-target engagement to downstream pharmacology with CeTEAM

Valerie, N. C. K.; Sanjiv, K.; Mortusewicz, O.; Zhang, S. M.; Rasti, A.; Langelier, M.-F.; Rehling, D.; Throup, A.; Desroses, M.; Wakchaure, P.; Almlof, I.; Alam, S.; Bostrom, J.; Bevc, L.; Stenmark, P.; Pascal, J. M.; Helleday, T.; Page, B. D. G.; Altun, M.

10.1101/2022.09.19.505646 — biochemistry — Posted on 2022-09-19

1753 Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 using Proximity Labeling and Affinity Purification

Aprosoff, C. M.; Dyakov, B. J. A.; Cheung, V. H. W.; Wong, C. J.; Palandra, M.; Gingras, A.-C.; Wyatt, H. D. M.

10.1101/2022.09.19.508447 — biochemistry — Posted on 2022-09-19

1754 Human immunodeficiency virus integration complexes are active following ordered addition of wild type integrase, viral DNA, and LEDGF/p75

Rabe, A. J.; Russo, J. A.; Larue, R. C.; Yoder, K. E.

10.1101/2022.09.19.508505 — biochemistry — Posted on 2022-09-19

1755 Genomics of PDGFR-rearranged hypereosinophilic syndrome

Rheinbay, E.; Qi, M.; Bouyssou, J.; Oler, A. J.; Thumm, L.; Makiya, M.; Maric, I.; Klion, A.; Lane, A.

10.1101/2022.09.19.508443 — genomics — Posted on 2022-09-19

1756 Gobies inhabiting natural CO2 seeps reveal acclimation strategies to long-term acidification

Suresh, S.; Mirasole, A.; Ravasi, T.; Vizzini, S.; Schunter, C.

10.1101/2022.09.18.508416 — evolutionary biology — Posted on 2022-09-19

1757 Golden section hypothesis of macroevolution: unification of metabolic scaling and Fibonacci sequence

Yang, X. G.; Wang, L.

10.1101/2022.09.19.508476 — evolutionary biology — Posted on 2022-09-19

1758 A Novel Gene REPTOR2 Activates the Autophagic Degradation of Wing Disc in pea aphid

Yuan, E.; Guo, H.; Chen, W.; Du, B.; Mi, Y.; Qi, Z.; Yuan, Y.; Zhu-Salzman, K.; Ge, F.; Sun, Y.

10.1101/2022.09.19.508482 — developmental biology — Posted on 2022-09-19

1759 Comparative transcriptomics reveals human-specific cortical features

Jorstad, N. L.; Song, J. H. T.; Exposito-Alonso, D.; Suresh, H.; Castro, N.; Krienen, F. M.; Yanny, A. M.; Close, J.; Gelfand, E.; Travaglini, K. J.; Basu, S.; Beaudin, M.; Bertagnolli, D.; Crow, M.; Ding, S.-L.; Eggermont, J.; Glandon, A.; Goldy, J.; Kroes, T.; Long, B.; McMillen, D.; Pham, T.; Rimorin, C.; Siletti, K.; Somasundaram, S.; Tieu, M.; Torkelson, A.; Ward, K.; Feng, G.; Hopkins, W. D.; Hollt, T.; Keene, C. D.; Linnarsson, S.; McCarroll, S. A.; Lelieveldt, B. P.; Sherwood, C. C.; Smith, K.; Walsh, C. A.; Dobin, A.; Gillis, J.; Lein, E. S.; Hodge, R. D.; Bakken, T. E.

10.1101/2022.09.19.508480 — neuroscience — Posted on 2022-09-19

1760 Temporal asymmetries and interactions between dorsal and ventral visual pathways during object recognition

Ayzenberg, V.; Simmons, C.; Behrmann, M.

10.1101/2022.09.17.508376 — neuroscience — Posted on 2022-09-19

1761 The vestibular calyceal junction is dismantled in response to diverse injuring stimuli in rats and humans

Maroto, A. F.; Borrajo, M.; Prades, S.; Callejo, A.; Amilibia, E.; Perez-Grau, M.; Roca-Ribas, F.; Castellanos, E.; Barrallo-Gimeno, A.; Llorens, J.

10.1101/2022.05.17.492294 — neuroscience — Posted on 2022-09-19

1762 Representing cells as sentences enables natural-language processing for single-cell transcriptomics

Dhodapkar, R. M.

10.1101/2022.09.18.508438 — bioinformatics — Posted on 2022-09-19

1763 Coupling machine learning and epidemiological modelling to characterise optimal fungicide doses when fungicide resistance is partial or quantitative

Taylor, N. P.; Cunniffe, N. J.

10.1101/2022.09.17.508365 — evolutionary biology — Posted on 2022-09-19

1764 Large variations in afforestation-related climate cooling and warming effects across short distances

Rohatyn, S.; Rotenberg, E.; Tatarinov, F.; Carmel, Y.; Yakir, D.

10.1101/2022.09.18.508428 — ecology — Posted on 2022-09-19

1765 Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in enteric nervous system

Ito, M.; Fujii, N.; Kohara, S.; Hori, S.; Tanaka, M.; Wittwer, C.; Kikuchi, K.; Iijima, T.; Kakimoto, Y.; Hirabayashi, K.; Kurotaki, D.; Jessen, H. J.; Saiardi, A.; Nagata, E.

10.1101/2022.09.19.508459 — molecular biology — Posted on 2022-09-19

1766 Chaperones Hsc70 and Hsp70 Play Distinct Roles in Bocaparvovirus Minute Virus of Canines Infection

Guo, J.; Sun, J.; Yan, Y.; Ji, K.; Hei, Z.; Zeng, L.; Xu, H.; Ren, X.; Sun, Y.

10.1101/2022.09.19.508470 — molecular biology — Posted on 2022-09-19

1767 Loss of Rab8a in B cells leads to increased antibody responses and class-switch recombination

Hernandez-Perez, S.; Sarapulov, A. V.; Balci, M. O.; Coffey, E.; Harada, A.; Mattila, P.

10.1101/2022.09.19.508414 — immunology — Posted on 2022-09-19

1768 HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era

Buhler, S.; Calderin Sollet, Z.; Bettens, F.; Schaefer, A.; Ansari, M.; Ferrari-Lacraz, S.; Villard, J.

10.1101/2022.09.14.507948 — immunology — Posted on 2022-09-19

1769 Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies

Sheward, D. J.; Kim, C.; Fischbach, J.; Muschiol, S.; Ehling, R. A.; Björkström, N. K.; Karlsson Hedestam, G. B.; Reddy, S. T.; Albert, J.; Peacock, T. P.; Murrell, B.

10.1101/2022.09.16.508299 — immunology — Posted on 2022-09-19

1770 Diverse long-range projections convey position information to the retrosplenial cortex.

Gianatti, M.; Garvert, A. C.; Vervaeke, K.

10.1101/2022.09.18.508427 — neuroscience — Posted on 2022-09-19

1771 Physiological constraints on the rapid dopaminergic modulation of striatal reward activity

Long, C.; Lee, K.; Yang, L.; Dafalias, T.; Wu, A. K.; Masmanidis, S. C.

10.1101/2022.09.16.508310 — neuroscience — Posted on 2022-09-19

1772 Reduced insulin signalling in neurons induces sex-specific health benefits

Baghdadi, M.; Nespital, T.; Mesaros, A.; Buschbaum, S.; Withers, D. J.; Grönke, S.; Partridge, L.

10.1101/2022.09.19.508502 — neuroscience — Posted on 2022-09-19

1773 A neuron that regulates locomotion makes a potential sensory cilium lying over the C. elegans egg-laying apparatus

Koelle, M. R.; Christie, N. T. M.

10.1101/2022.09.19.508547 — neuroscience — Posted on 2022-09-19

1774 Can neural correlates of encoding explain the context dependence of reward-enhanced memory?

Hellerstedt, R.; Bekinschtein, T. A.; Talmi, D.

10.1101/2022.09.19.508490 — neuroscience — Posted on 2022-09-19

1775 Seeing speech: The cerebral substrate of tickertape synesthesia.

Hauw, F.; El Soudany, M.; Rosso, C.; Daunizeau, J.; Cohen, L.

10.1101/2022.09.19.508477 — neuroscience — Posted on 2022-09-19

1776 Antidiabetic, antioxidant and in silico molecular docking of Xeroderris stuhlmannii (Taub.) Mendonca & E.P. Sousa phytochemical compounds on human pancreatic α-amylase and human lysosomal acid-α-glucosidase

Nyathi, B.; Bvunzawabaya, J. T.; Manzombe, E.; Selemani, M. A.; Tsotsoro, K.; Munyuki, G.; Rwere, F.

10.1101/2022.09.16.508336 — plant biology — Posted on 2022-09-19

1777 OPA1 Downregulation in Skeletal Muscle Induces MERC formation in an ATF4-Dependent Manner

Hinton, A.; Katti, P.; Mungai, M.; Hall, D.; Koval, O.; Shao, J.; Vue, Z.; Christensen, T. A.; Lopez, E. G.; Rostami, R.; Neikirk, K.; Lam, J.; Alghanem, A.; Ponce, J.; Hicsasmaz, I.; Streeter, J.; Schickling, B.; Bacevac, S.; Grueter, C.; Marshall, A.; Beasley, H. K.; DoKoo, Y.; Bodine, S.; Nava, N. G. R.; Quintana, A.; Trushina, E.; Weatherford, E.; Murray, S. A.; Salisbury, J.; Song, L.-S.; Grumbach, I.; Exil, V.; Pereira, R. O.; Glancy, B.; Abel, E. D.

10.1101/2022.09.12.507669 — biophysics — Posted on 2022-09-19

1778 Thermoplasmonic induced vesicle fusion for investigating membrane protein phase affinity

Pescador, G. M.; Arastoo, M. R.; Chiantia, S.; Daniels, R.; Bendix, P. M.

10.1101/2022.09.19.508467 — biophysics — Posted on 2022-09-19

1779 Accurate prediction of RNA secondary structure including pseudoknots through solving minimum-cost flow with learned potentials

Bu, D.; Gong, T.; Ju, F.

10.1101/2022.09.19.508461 — bioinformatics — Posted on 2022-09-19

1780 Kidney-specific methylation patterns correlate with kidney function and are lost upon kidney disease progression

Sagy, N.; Meyrom, N.; Beckerman, P.; Pleniceanu, O.; Bar, D. Z.

10.1101/2022.09.19.508466 — bioinformatics — Posted on 2022-09-19

1781 Using pressure-driven flow systems to evaluate laser speckle contrast imaging

Sullender, C. T.; Santorelli, A.; Richards, L. M.; Mannava, P. K.; Smith, C.; Dunn, A. K.

10.1101/2022.09.16.508276 — bioengineering — Posted on 2022-09-19

1782 The time to initiate retrieval of a memory depends on recency

Bright, I. M.; Singh, I.; Didomenica, R.; Oliva, A.; Howard, M. W.

10.1101/2022.09.16.508287 — animal behavior and cognition — Posted on 2022-09-19

1783 Visual processing and collective motion-related decision-making in desert locusts

Bleichman, I.; Yadav, P.; Ayali, A.

10.1101/2022.09.19.508462 — animal behavior and cognition — Posted on 2022-09-19

1784 Boreal Forest Height Mapping using Sentinel-1 Time Series and improved LSTM model

Ge, S.; Gu, H.; Su, W.; Rauste, Y.; Praks, J.; Antropov, O.

10.1101/2022.09.18.508417 — ecology — Posted on 2022-09-19

1785 Quantifying climate change impacts on plant functional composition and soil nitrogen fixation in Mediterranean grasslands

Bomfim, B.; Dawson, H. R.; Reed, P. B.; Bridgham, S.; Bohannan, B.; Shek, K.; Silva, L. C. R.

10.1101/2022.09.16.508323 — ecology — Posted on 2022-09-19

1786 Effect and mechanism of black soybean peptides alleviating oxidative damage in the celiac disease cell model

Cui, C.; Wang, N.; Gao, E.; Yu, Q.; Sun, X.; Hu, M.; Xu, Q.; Cui, N.; Zheng, Y.; Wang, F.; Wang, C.

10.1101/2022.09.19.508472 — cell biology — Posted on 2022-09-19

1787 Pathogens in exacerbations of chronic rhinosinusitis differ in sensitivity to silver nanoparticles

Szaleniec, J.; Gibala, A.; Stalinska, J.; Ocwieja, M.; Zeliszewska, P.; Drukala, J.; Szaleniec, M.; Gosiewski, T.

10.1101/2022.01.03.474872 — microbiology — Posted on 2022-09-19

1788 Staphylococcus aureus virulence factor expression matters: input from targeted proteomics shows Panton-Valentine leucocidin impact on mortality

Pivard, M.; Bastien, S.; Macavei, I.; Mouton, N.; Rasigade, J.-P.; Couzon, F.; Carriere, R.; Moreau, K.; Lemoine, J.; Vandenesch, F.

10.1101/2022.09.18.508069 — microbiology — Posted on 2022-09-19

1789 HDAC7 controls anti-viral and anti-tumor immunity by CD8+ T cells

Yerinde, C.; Keye, J.; Durlanik, S.; Freise, I.; Nowak, F.; Hsiao, H.-J.; Letizia, M.; Schlickeiser, S.; Obermayer, B.; Huck, A.; Friedrich, M.; Wu, H.; Kunkel, D.; Kuehl, A. A.; Bauer, S.; Thiel, A.; Siegmund, B.; Glauben, R.; Weidinger, C.

10.1101/2022.09.18.508452 — immunology — Posted on 2022-09-19

1790 Distributed coding of evidence accumulation across the mouse brain using microcircuits with a diversity of timescales

Imani, E.; Radkani, S.; Hashemi, A.; Harati, A.; Pourreza, H.; Goudarzi, M. M.

10.1101/2022.09.17.506014 — neuroscience — Posted on 2022-09-19

1791 Abnormal intrinsic neural timescale in Parkinson's disease

Wei, Y.; Zhang, C.; Peng, Y.; Chen, C.; Han, S.; Wang, W.; Lu, H.; Cheng, J.

10.1101/2022.09.17.508074 — neuroscience — Posted on 2022-09-19

1792 To be and not to be: Wide-field Ca2+ imaging reveals neocortical functional segmentation combines stability and flexibility

Nietz, A. K.; Streng, M. L.; Popa, L. S.; Carter, R. E.; Flaherty, E.; Aronson, J. D.; Ebner, T.

10.1101/2022.09.16.508301 — neuroscience — Posted on 2022-09-19

1793 Relative Brain Age Is Associated with Socioeconomic Status and Anxiety/Depression Problems in Youth

Cohen, J. W.; Ramphal, B.; Deserisy, M.; Zhao, Y.; Pagliaccio, D.; Colcombe, S.; Milham, M. P.; Margolis, A. E.

10.1101/2022.09.15.505331 — neuroscience — Posted on 2022-09-19

1794 Disturbing standing balance evokes an error-related negativity

Payne, A. M.; Ting, L. H.; Hajcak, G.

10.1101/2022.09.16.508295 — neuroscience — Posted on 2022-09-19

1795 The Role of Frontal Eye Field in Saccadic Mixed-strategy Decision-making

Xie, S.; Abunafessa, A.; Gu, Y.; Yang, M.; Wang, X.; Tu, J.; Thevarajah, D.; Dorris, M. C.

10.1101/2022.09.18.508403 — neuroscience — Posted on 2022-09-19

1796 From the ear flap to the nerve: A complete computer model of the peripheral auditory system

Tichacek, O.; Mistrik, P.; Jungwirth, P.

10.1101/2022.04.23.489223 — neuroscience — Posted on 2022-09-19

1797 Quercetin reduces APP expression, oxidative stress and mitochondrial dysfunction in the N2a/APPswe cells via ERK1/2 and AKT pathways

Tang, Z.; Guo, M.; Peng, Y.; Xiao, Y.; Zhang, T.; Ni, R.; Qi, X.

10.1101/2022.09.18.508406 — neuroscience — Posted on 2022-09-19

1798 PrePCI: A structure- and chemical similarity-informed database of predicted protein compound interactions

Trudeau, S. J.; Hwang, H.; Mathur, D.; Begum, K.; Petrey, D.; Murray, D.; Honig, B.

10.1101/2022.09.17.508184 — systems biology — Posted on 2022-09-19

1799 Towards genome-engineering in complex cyanobacterial communities: RNA-guided transposition in Anabaena

Arevalo, S.; Rico, D. P.; Abarca, M. D.; Dijkhuizen, L. W.; Lindblad, P.; Flores, E.; Nierzwicki-Bauer, S.; Schluepmann, H.

10.1101/2022.09.18.508393 — synthetic biology — Posted on 2022-09-19

1800 Genome-wide Analysis of Bromodomain Gene Family in Arabidopsis and Rice

V., A. T.; Sanyal, R. P.; Misra, H. S.; Saini, A.

10.1101/2022.02.08.479518 — plant biology — Posted on 2022-09-19

1801 Influence of Sodium Salicylate on Adventitious Organogenesis of a Commercial Cucumber Cultivar

Miguel, J. F.

10.1101/2022.09.16.508332 — plant biology — Posted on 2022-09-19

1802 A deep learning workflow for quantification of Micronuclei in DNA damage studies in cultured cancer cell lines: a proof of principle investigation

Surendranath, K.; Panchbhai, A.; Ishanzadeh, M. C.; Pankanti, S.; Sidali, A.; Solaiman, N.; Radhakrishnan, K.; Murphy, J. J.

10.1101/2022.09.18.508405 — cancer biology — Posted on 2022-09-19

1803 Phase separation in amino acid mixtures is governed by composition

De Sancho, D.

10.1101/2022.03.02.482633 — biophysics — Posted on 2022-09-19

1804 SPRUCE: Single-cell Pairwise Relationships Untangled by Composite Embedding model

Subedi, S.; Park, Y.

10.1101/2022.09.16.508327 — bioinformatics — Posted on 2022-09-19

1805 FrameRate: learning the coding potential of unassembled metagenomic reads

Liu-Wei, W.; Aubrey, W.; Clare, A.; Hoehndorf, R.; Creevey, C. J.; Dimonaco, N. J.

10.1101/2022.09.16.508314 — bioinformatics — Posted on 2022-09-19

1806 ADRA2B and HTR1A: An updated study of the biogenic amine receptors reveals novel conserved motifs which play key role in Mental Disorders.

Papageorgiou, L.; Christou, E.; Louka, E.; Andreou, A.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Chrousos, G. P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508280 — bioinformatics — Posted on 2022-09-19

1807 SHEPHARD: a modular and extensible software architecture for analyzing and annotating large protein datasets

Ginell, G. M.; Flynn, A. J.; Holehouse, A. S.

10.1101/2022.09.18.508433 — bioinformatics — Posted on 2022-09-19

1808 Predicting A/B compartments from histone modifications using deep learning

Zheng, S.; Thakkar, N.; Harris, H. L.; Zhang, M.; Liu, S.; Gerstein, M.; Aiden, E. L.; Rowley, J.; Noble, W. S.; Gursoy, G.; Singh, R.

10.1101/2022.04.19.488754 — bioinformatics — Posted on 2022-09-19

1809 Towards In-Silico CLIP-seq: Predicting Protein-RNA Interaction via Sequence-to-Signal Learning

Horlacher, M.; Wagner, N.; Moyon, L.; Kuret, K.; Goedert, N.; Salvatore, M.; Ule, J.; Gagneur, J.; Winther, O.; Marsico, A.

10.1101/2022.09.16.508290 — bioinformatics — Posted on 2022-09-19

1810 Genetic, clinical underpinnings of subtle early brain change along Alzheimer's dimensions

WEN, J.; Yang, Z.; Nasrallah, I.; Cui, Y.; Erus, G.; Srinivasan, D.; Abdulkadir, A.; Mamourian, E.; Hwang, G.; Singh, A.; Bergman, M.; Bao, J.; Varol, E.; Zhou, Z.; Boquet-Pujadas, A.; Chen, J.; Toga, A. W.; Saykin, A. J.; Hohman, T.; Thompson, P.; Villeneuve, S.; Gollub, R.; Sotiras, A.; Wittfeld, K.; Grabe, H.; Tosun, D.; Bilgel, M.; An, Y.; Marcus, D.; LaMontagne, P. J.; Heckbert, S.; Austin, T.; Launer, L.; Espeland, M.; Masters, C.; Maruff, P.; Fripp, J.; Johnson, S. C.; Morris, j.; Albert, M.; Nick, R.; Resnick, S. M.; Ferrucci, L.; Fan, Y.; Mohamad, H.; Wolk, D.; Shen, L.; Shou, H.; Dav

10.1101/2022.09.16.508329 — bioengineering — Posted on 2022-09-19

1811 Comparing acute IOP-induced lamina cribrosa deformations pre-mortem and post-mortem

Wei, J.; Hua, Y.; Yang, B.; Wang, B.; Schmitt, S. E.; Wang, B.; Lucy, K. A.; Ishikawa, H.; Schuman, J. S.; Smith, M. A.; Wollstein, G.; Sigal, I. A.

10.1101/2022.09.18.508448 — bioengineering — Posted on 2022-09-19

1812 The Mouse N-Glycome Atlas - High-resolution N-glycan analysis of 23 mouse tissues.

Helm, J.; Mereiter, S.; Oliveira, T.; Penninger, J. M.; Altmann, F.; Stadlmann, J.

10.1101/2022.09.19.508483 — biochemistry — Posted on 2022-09-19

1813 A benchmarking of human Y-chromosomal haplogroup classifiers from whole-genome and whole-exome sequence data

10.1101/2022.09.19.508481 — genomics — Posted on 2022-09-19

1814 TransCistor reveals the landscape of cis-regulatory long noncoding RNAs

Chouvardas, P.; Zimmerli, M.; Hanhart, D.; Moser, M.; Guillen-Ramirez, H. A.; Mishra, S.; Esposito, R.; Polidori, T.; Widmer, M.; Garcia-Perez, R.; Kruithof-de Julio, M.; Pervouchine, D. D.; Mele, M.; Johnson, R.

10.1101/2022.09.18.508380 — genomics — Posted on 2022-09-19

1815 Development of the First High-Density Linkage Map in the Maize Weevil, Sitophilus zeamais

Baltzegar, J. F.; Gould, F.

10.1101/2022.09.16.508320 — genetics — Posted on 2022-09-19

1816 Drought adaptability of different subspecies of tetraploid wheat (Triticum turgidum) under contrasting moisture conditions: association with solvent retention capacity and quality-related traits

Saeidnia, F.; Shoormij, F.; Mirlohi, A.; Soleimani Kartalaei, E.; Mohammadi, M.; Sabzalian, M. R.

10.1101/2022.09.19.508520 — genetics — Posted on 2022-09-19

1817 Environment-dependent epistasis increases phenotypic diversity in gene regulatory networks

Baier, F.; Gauye, F.; Perez-Carrasco, R.; Payne, J. L.; Schaerli, Y.

10.1101/2022.09.18.508240 — evolutionary biology — Posted on 2022-09-19

1818 Ancient multiplicity in cyclic nucleotide-gated (CNG) cation channel repertoire was reduced in the ancestor of Olfactores before re-expansion by whole genome duplications in vertebrates

Lagman, D.; Haines, H. J.; Abalo, X. M.; Larhammar, D.

10.1101/2022.09.16.508201 — evolutionary biology — Posted on 2022-09-19

1819 Vestigial-dependent recruitment contributes to robust patterning but is not required for wing-fate induction in Drosophila

Flores-Flores, M.; Munoz-Nava, L. M.; Zartman, J. J.; Nahmad, M.

10.1101/2022.09.18.508456 — developmental biology — Posted on 2022-09-19

1820 Transient Polycomb activity represses developmental genes in growing oocytes.

Jarred, E. G.; Qu, Z.; Tsai, T.; Oberin, R.; Petautschnig, S.; Bildsoe, H.; Pederson, S. M.; Zhang, Q.-H.; Stringer, J. M.; Carroll, J.; Gardner, D. K.; van den Buuse, M.; Sims, N.; Gibson, W.; Adelson, D. L.; Western, P. S.

10.1101/2022.09.18.508436 — developmental biology — Posted on 2022-09-19

1821 Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion

Hepowit, N. L.; Moon, B. J.; Dickson, R. C.; MacGurn, J. A.

10.1101/2022.05.20.492841 — cell biology — Posted on 2022-09-19

1822 Chance and contingency in B cell evolution limit the similarity of antibody responses to infection across individuals

Vieira, M. C.; Palm, A.-K. E.; Stamper, C. T.; Tepora, M. E.; Nguyen, K. D.; Pham, T. D.; Boyd, S. D.; Wilson, P. C.; Cobey, S.

10.1101/2022.09.16.508315 — immunology — Posted on 2022-09-19

1823 Multi-modal Efficacy of a Chimeric Vesiculovirus Expressing the Morreton Glycoprotein in Sarcoma

Dumbauld, C.; Barro, O.; Elliott, N. M.; Zhou, Y.; Gabere, M.; Raupach, E.; Baker, A. T.; Barrett, M. T.; Buetow, K.; Jacobs, B.; Seetharam, M.; Borad, M.; Nagalo, B. M.

10.1101/2022.09.18.508434 — immunology — Posted on 2022-09-19

1824 Microbiota-stimulated Interleukin-22 regulates brain neurons and protects against stress-induced anxiety

Ilanges, A.; Xia, M.; Lu, J.; Chen, L.; Shiao, R.; Wang, C.; Feng, R.; Jin, Z.; Yi, H.; Qi, Q.; Li, J.; Schneeberger, M.; Lu, B.; Friedman, J. M.; Yu, X.

10.1101/2022.09.16.508224 — immunology — Posted on 2022-09-19

1825 A T1R-independent mechanism for responses to hyperosmotic sugars involves a carbonic anhydrase-sensitive mechanism in Type III receptor cells

Kalyanasundar, B.; Blonde, G.; Spector, A. C.; Travers, S. P.

10.1101/2022.09.16.508275 — neuroscience — Posted on 2022-09-19

1826 Gateway Identity and Spatial Remapping in a Combined Grid and Place Cell Attractor.

Baumann, T.; Mallot, H. A.

10.1101/2022.05.11.491479 — neuroscience — Posted on 2022-09-19

1827 Cascades of neuronal plasticity in the macaque visual cortex

Koyano, K. W.; Esch, E. M.; Hong, J. J.; Waidmann, E. N.; Leopold, D. A.

10.1101/2022.09.17.508292 — neuroscience — Posted on 2022-09-19

1828 Prefrontal neuronal dynamics in the absence of task execution

Pu, S.; Dang, W.; Qi, X.; Constantinidis, C.

10.1101/2022.09.16.508324 — neuroscience — Posted on 2022-09-19

1829 Acute stress impairs target enhancement but not disrtractor suppression in attention selection: Evidence from the N2pc and Pd

Luo, Y.; Nian, J.; Yang, R.; Xie, J.; Zhang, Y.

10.1101/2022.09.16.508346 — neuroscience — Posted on 2022-09-19

1830 A Computational Model of Learning Flexible Navigation in a Maze by Layout-Conforming Replay of Place Cells

Gao, Y.

10.1101/2022.09.16.508350 — neuroscience — Posted on 2022-09-19

1831 Predictive processing of scene layout depends on naturalistic depth of field

Gandolfo, M.; Naegele, H.; Peelen, M. V.

10.1101/2021.11.08.467670 — neuroscience — Posted on 2022-09-19

1832 Loss of LRP1 from GABAergic neurons impairs short-term memory function

Uner, A. A.; Hou, Z.-S.; Aydogan, A.; Rodrigues, K. C. d. C.; Young, J.; Choi, A.; Yang, W.-M.; Kang, J.; Kim, W.; PREVOT, V.; Caldarone, B. J.; Lee, H.; Kim, Y.-B.

10.1101/2022.09.17.508390 — neuroscience — Posted on 2022-09-19

1833 Structural determinants of relaxation dynamics in chemical reaction networks

Himeoka, Y.; Kirkegaard, J.; Mitarai, N.; Krishna, S.

10.1101/2022.05.25.493374 — systems biology — Posted on 2022-09-19

1834 Mental fatigue impairs physical performance but not the neural drive to the muscle

Alix-Fages, C.; Jimenez-Martinez, P.; Souza de Oliveira, D.; Mock, S.; Balsalobre-Fernandez, C.; Del Vecchio, A.

10.1101/2022.09.16.508212 — physiology — Posted on 2022-09-19

1835 The energetic effect of hip flexion and retraction in walking at different speeds: a modeling study

Jin, J.; Kistemaker, D.; van Dieen, J. H.; Daffertshofer, A.; Bruijn, S. M.

10.1101/2022.09.17.508363 — physiology — Posted on 2022-09-19

1836 Diverse transcriptomic response of cellular system following low-dose exposure of mesoporous nanoparticles

Mittal, D.; Ali, S. A.

10.1101/2022.09.16.508239 — pharmacology and toxicology — Posted on 2022-09-19

1837 A novel transcriptional signature identifies T-cell infiltration in high-risk paediatric cancer

Mayoh, C.; Gifford, A.; Terry, R.; Lau, L. M.; Wong, M.; Rao, P.; Shai-Hee, T.; Saletta, F.; Khuong-Quang, D.-A.; Qin, V.; Mateos, M.; Meyran, D.; Miller, K. E.; Yuksel, A.; Mould, E. V.; Bowen-James, R.; Govender, D.; Senapati, A.; Zhukova, N.; Omer, N.; Dholaria, H.; Alvaro, F.; Tapp, H.; Diamond, Y.; Dalla Pozza, L.; Moore, A. S.; Nicholls, W.; Gottardo, N. G.; McCowage, G.; Hansford, J. R.; Khaw, S.-L.; Wood, P. J.; Catchpoole, D.; Cottrell, C. E.; Mardis, E. R.; Marshall, G. M.; Tyrrell, V.; Haber, M.; Ziegler, D. S.; Vittorio, O.; Trapani, J. A.; Cowley, M. J.; Neeson, P. J.; Ekert, P. G

10.1101/2022.09.16.508179 — cancer biology — Posted on 2022-09-19

1838 Cells in the Polyaneuploid Cancer Cell (PACC) state have increased metastatic potential

Mallin, M. M.; Kim, N.; Choudhury, M. I.; Lee, S. J.; An, S. S.; Sun, S. X.; Konstantopoulos, K.; Pienta, K. J.; Amend, S. R.

10.1101/2022.09.16.508155 — cancer biology — Posted on 2022-09-19

1839 Functional precision profiling reveals non-mutational rewiring of kinase signaling networks in colorectal cancer

Plattner, C.; Lamberti, G.; Blattmann, P.; Kirchmair, A.; Rieder, D.; Loncova, Z.; Sturm, G.; Scheidl, S.; Ijsselsteijn, M. E.; Fotakis, G.; Noureen, A.; Lisandrelli, R.; Boeck, N.; Nemati, N.; Krogsdam, A.; Daum, S.; Finotello, F. E.; Somarakis, A.; Schaefer, A.; Wilflingseder, D.; Gonzalez Acera, M.; Oefner, D.; Huber, L. A.; Clevers, H.; Becker, C.; Farin, H. F.; Greten, F. R.; Aebersold, R.; da Cunha Carvalho de Miranda, N. F.; Trajanoski, Z.

10.1101/2022.09.16.508204 — cancer biology — Posted on 2022-09-19

1840 DRDs and Brain Derived Neurotrophic Factor share a common therapeutic ground: A novel bioinformatic approach sheds new light towards pharmacological treatment of Cognitive and Behavioral Disorders.

Papageorgiou, L.; Kalospyrou, E.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Chrousos, G. P.; Exarchos, T. P.; Vlamos, P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508267 — bioinformatics — Posted on 2022-09-19

1841 Reconstructor: A COBRApy compatible tool for automated genome-scale metabolic network reconstruction with parsimonious flux-based gap-filling

Jenior, M. L.; Glass, E. M.; Papin, J. A.

10.1101/2022.09.17.508371 — bioinformatics — Posted on 2022-09-19

1842 Compressed Data Structures for Population-Scale Positional Burrows-Wheeler Transforms

Bonizzoni, P.; Boucher, C.; Cozzi, D.; Gagie, T.; Kashgouli, S.; Köppl, D.; Rossi, M.

10.1101/2022.09.16.508250 — bioinformatics — Posted on 2022-09-19

1843 IRescue: single cell uncertainty-aware quantification of transposable elements expression

Polimeni, B.; Marasca, F.; Ranzani, V.; Bodega, B.

10.1101/2022.09.16.508229 — bioinformatics — Posted on 2022-09-19

1844 Comparison of calling pipelines for whole genome sequencing: an empirical study demonstrating the importance of mapping and alignment

Betschart, R.; Thiery, A.; Aguilera-Garcia, D.; Zoche, M.; Moch, H.; Twerenbold, R.; Zeller, T.; Blankenberg, S.; Ziegler, A.

10.1101/2022.09.18.508404 — bioinformatics — Posted on 2022-09-19

1845 Re-exploiting multiple RNA-seq data to identify transcript variations in Podospora anserina

Lelandais, G.; Remy, D.; Malagnac, F.; Grognet, P.

10.1101/2022.09.16.508226 — genomics — Posted on 2022-09-19

1846 Analysis of somatic mutations in senescent cells using single-cell whole-genome sequencing

Zhang, L.; De Cecco, M.; Lee, M.; Hao, X.; Maslov, A. Y.; Montagna, C.; Campisi, J.; Dong, X.; Sedivy, J. M.; Vijg, J.

10.1101/2022.09.16.508266 — genomics — Posted on 2022-09-19

1847 Incorporating selection pressures into risk predictions of pesticide resistance evolution in arthropod pests

Thia, J. A.; Maino, J.; Kelly, A.; Hoffmann, A. A.; Umina, P. A.

10.1101/2022.04.18.488707 — evolutionary biology — Posted on 2022-09-19

1848 Differential transcriptomic responses to heat stress in surface and subterranean diving beetles

Beasley-Hall, P. G.; Bertozzi, T.; Bradford, T. M.; Foster, C. S. P.; Jones, K.; Tierney, S. M.; Humphreys, W. F.; Austin, A. D.; Cooper, S. J. B.

10.1101/2021.12.12.470823 — evolutionary biology — Posted on 2022-09-19

1849 The limits of evolutionary convergence in sympatry: reproductive interference and historical constraints leading to local diversity in warning traits

Maisonneuve, L.; Elias, M.; Smadi, C.; Llaurens, V.

10.1101/2021.01.22.427743 — evolutionary biology — Posted on 2022-09-19

1850 How do age, available support, gender and attitudes affect the quality of data collected by young citizen scientists in an ecological research project?

Aivelo, T.

10.1101/2022.09.16.508269 — ecology — Posted on 2022-09-19

1851 Nutrient addition increases grassland resistance during dry and wet climate extremes despite functional diversity loss

Chen, Q.; Wang, S.-P.; Seabloom, E. W.; Isbell, F.; Borer, E. T.; Bakker, J. D.; Bharath, s.; Roscher, C.; Peri, P. L.; Power, S. A.; Donohue, I.; Stevens, C.; Ebeling, A.; Nogueira, C.; Caldeira, M. C.; MacDougall, A.; Moore, J.; Bagchi, S.; Jentsch, A.; Tedder, M.; Kirkman, K.; Alberti, J.; Hautier, Y.

10.1101/2022.09.16.508233 — ecology — Posted on 2022-09-19

1852 A new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress

Reinhard, J.; Starke, L.; Klose, C.; Haberkant, P.; Hammaren, H.; Stein, F.; Klein, O.; Berhorst, C.; Stumpf, H.; Saenz, J. P.; Hub, J.; Schuldiner, M.; Ernst, R.

10.1101/2022.09.15.508072 — cell biology — Posted on 2022-09-19

1853 The diazepam binding inhibitors modulation of the GABA-A receptor is subunit-dependent

Borchardt, J. S.; Blecker, L. M.; Tung, A.; Satyshur, K. A.; Czajkowski, C.

10.1101/2021.08.13.456294 — neuroscience — Posted on 2022-09-19

1854 Historical biogeography of Cannabis in the Iberian Peninsula: palynological evidence

Rull, V.; Burjachs, F.; Carrion, J.; Ejarque, A.; Fernandez, S.; Lopez-Saez, J. A.; Luelmo-Lautenschlaeger, R.; Ochando, J.; Perez-Diaz, S.; Revelles, J.; Riera, S.; Rodriguez, S.

10.1101/2022.09.16.508344 — paleontology — Posted on 2022-09-19

1855 Mechanochemical rules for shape-shifting filaments that remodel membranes

Meadowcroft, B.; Palaia, I.; Pfitzner, A.-K.; Roux, A.; Baum, B.; Saric, A.

10.1101/2022.05.10.490642 — biophysics — Posted on 2022-09-19

1856 UNIQmin, an alignment-free tool to study viral sequence diversity across taxonomic lineages: a case study of monkeypox virus

Chong, L. C.; Khan, A. M.

10.1101/2022.08.09.503271 — bioinformatics — Posted on 2022-09-19

1857 A non-coding A-to-T Kozak site change related to the transmissibility of Alpha, Delta and Omicron VOCs

Yang, J.; Zhang, G.; Yu, D.; Cao, R.; Wu, X.; Ling, Y.; Pan, Y.-H.; Yi, C.; Sun, X.; Sun, B.; Zhang, Y.; Zhao, G.-P.; Li, Y.; Li, H.

10.1101/2021.04.30.442029 — evolutionary biology — Posted on 2022-09-19

1858 Hunting Drosophila viruses from wild populations: a novel isolation approach and characterisation of viruses

Bruner-Montero, G.; Luque, C.; Ding, S. D.; Day, J. P.; Jiggins, F. M.

10.1101/2022.09.16.508214 — evolutionary biology — Posted on 2022-09-19

1859 Hamilton's rule, the evolution of behavior rules and the wizardry of control theory

Lehmann, L.

10.1101/2022.06.14.496167 — evolutionary biology — Posted on 2022-09-19

1860 Number and proportion of P. falciparum gametocytes vary from acute infection to chronic parasite carriage despite unaltered sexual commitment rate

van Dijk, H.; Ferreira Lima, N.; Kampmann, M.; Gabel, M.; Dabbas, U.; Doumbo, S.; Cisse, H.; Li, S.; Jeninga, M.; Thomson Luque, R.; Doumtabe, D.; Petter, M.; Kayentao, K.; Ongoiba, A.; Bousema, T.; Crompton, P. D.; Traore, B.; Graw, F.; Portugal, S.

10.1101/2021.11.05.467456 — microbiology — Posted on 2022-09-19

1861 Proinflammatory innate cytokines and metabolomic signatures shape the T cell response in active COVID-19

Binayke, A.; Zaheer, A.; Dandotiya, J.; Gupta, S. K.; Mani, S.; Tripathy, M. R.; Madan, U.; Shrivastava, T.; Kumar, Y.; Pandey, A. K.; Rathore, D. K.; Awasthi, A.

10.1101/2022.03.11.483930 — immunology — Posted on 2022-09-19

1862 Language and the cerebellum: structural connectivity to the eloquent brain

Jobson, K. R.; Hoffman, L. J.; Metoki, A.; Popal, H.; Dick, A. S.; Reilly, J.; Olson, I. R.

10.1101/2022.04.19.488812 — neuroscience — Posted on 2022-09-19

1863 Metabolic Signatures of Performance in Elite World Tour Professional Cyclists

Nemkov, T.; Cendali, F.; Stefanoni, D.; Martinez, J.; Hansen, K. C.; San-Millan, I.; D'Alessandro, A.

10.1101/2022.09.13.507793 — biochemistry — Posted on 2022-09-19

1864 Electrochemical disruption of extracellular electron transfer inhibits Pseudomonas aeruginosa cell survival within biofilms and is synergistic with antibiotic treatment

Jimenez Otero, F.; Newman, D. K.; Tender, L. M.

10.1101/2022.09.15.508205 — microbiology — Posted on 2022-09-19

1865 Age and micronutrient effects on the microbiome in a mouse model of zinc depletion and supplementation

Davis, E. W.; Wong, C. P.; Arnold, H. K.; Kasschau, K.; Gaulke, C. A.; Sharpton, T. J.; Ho, E.

10.1101/2022.09.16.508248 — microbiology — Posted on 2022-09-19

1866 The differential regulation of placenta trophoblast bisphosphoglycerate mutase in fetal growth restriction: preclinical study in mice and observational histological study of human placenta.

Stroganov, S.; Harris, T.; Fellus-Alyagor, L.; Ben Moyal, L.; Plitman Mayo, R.; Golani, O.; Brandis, A.; Mehlman, T.; Kovo, M.; Biron-Shental, T.; Dekel, N.; Neeman, M.

10.1101/2022.09.14.507932 — physiology — Posted on 2022-09-19

1867 RNAlight: a machine learning model to identify nucleotide features determining RNA subcellular localization

Yuan, G.-H.; Wang, Y.; Wang, G.-Z.; Yang, L.

10.1101/2022.09.16.508211 — bioinformatics — Posted on 2022-09-19

1868 Lost In The Forest

Smith, H. L.; Biggs, P. J.; French, N. P.; Smith, A. N.; Marshall, J. C.

10.1101/2022.09.12.507676 — bioinformatics — Posted on 2022-09-19

1869 Common and distinct genetic architecture of age at diagnosis of diabetes in South Indian and European populations

Srinivasan, S.; Liju, S.; Sathish, N.; Siddiqui, M. K.; Ranjit, A. M.; Pearson, E. R.; Doney, A. S. F.; Viswanathan, M.; Venkatesan, R.; Palmer, C. N.

10.1101/2022.09.14.508063 — genetics — Posted on 2022-09-19

1870 The mobilizable plasmid P3 of Salmonella enterica serovar Typhimurium SL1344 depends on the P2 plasmid for conjugative transfer into a broad range of bacteria in vitro and in vivo

Gaissmaier, M. S.; Laganenka, L.; Herzog, M. K.-M.; Bakkeren, E.; Hardt, W.-D.

10.1101/2022.09.15.508199 — microbiology — Posted on 2022-09-19

1871 Neurofibromin 1 mediates sleep depth in Drosophila

Brown, E. B.; Zhang, J.; Lloyd, E.; Lanzon, E.; Botero, V.; Tomchik, S.; Keene, A. C.

10.1101/2022.09.15.508161 — neuroscience — Posted on 2022-09-19

1872 Distinct brain networks for remote episodic memory depending on content and emotional value

Auguste, A. L.; Fourcaud-Trocme, N.; Meunier, D.; Gros, A.; Garcia, S.; Messaoudi, B.; Thevenet, M.; Ravel, N.; Veyrac, A.

10.1101/2022.09.16.508241 — neuroscience — Posted on 2022-09-19

1873 Cholinergic boutons are distributed along the dendrites and somata of VIP neurons in the inferior colliculus

Kwapiszewski, J. T.; Rivera-Perez, L. M.; Roberts, M. T.

10.1101/2022.09.18.508423 — neuroscience — Posted on 2022-09-19

1874 Post-mating parental behavior trajectories differ across four species of deer mice

Khadraoui, M.; Merritt, J. R.; Hoekstra, H. E.; Bendesky, A.

10.1101/2022.09.18.508265 — animal behavior and cognition — Posted on 2022-09-19

1875 Higher-order dialectic variation and syntactic convergence in the complex warble song of budgerigars

Madabhushi, A. J.; Wewhare, N.; Binwal, P.; Krishnan, A.

10.1101/2022.09.18.508412 — animal behavior and cognition — Posted on 2022-09-19

1876 A spatiotemporal map of the aging mouse brain reveals white matter tracts as vulnerable foci

Hahn, O.; Foltz, A. G.; Atkins, M.; Kedir, B.; Moran-Losada, P.; Guldner, I. H.; Munson, C.; Kern, F.; Palovics, R.; Lu, N.; Kaur, A.; Hull, J.; Huguenard, J.; Keller, A.; Lehallier, B.; Wyss-Coray, T.

10.1101/2022.09.18.508419 — neuroscience — Posted on 2022-09-18

1877 Conserved whole-brain spatiomolecular gradients shape adult brain functional organization

Vogel, J. W.; Alexander-Bloch, A.; Wagstyl, K.; Bertolero, M.; Markello, R.; Pines, A.; Sydnor, V. J.; Diaz-Papkovich, A.; Hansen, J.; Evans, A. C.; Bernhardt, B.; Misic, B.; Satterthwaite, T.; Seidlitz, J.

10.1101/2022.09.18.508425 — neuroscience — Posted on 2022-09-18

1878 Quotidian Profile of Vergence Angle in Ambulatory Subjects Monitored with Wearable Eye Tracking Glasses

Dilbeck, M. D.; Gentry, T. N.; Economides, J. R.; Horton, J. C.

10.1101/2022.09.14.506830 — neuroscience — Posted on 2022-09-18

1879 Divisive Normalization Circuits Faithfully Represent Auditory and Visual Stimuli

Lazar, A. A.; Liu, T.; Zhou, Y.

10.1101/2022.09.17.506431 — neuroscience — Posted on 2022-09-18

1880 Medial accumbens shell spiny projection neurons encode relative reward preference

Pedersen, C. E.; Castro, D. C.; Hjort, M. M.; Zhou, Z. C.; Piantadosi, S. C.; Gowrishankar, R.; Kan, S. A.; Murphy, P. J.; O'Neill, P. R.; Bruchas, M.

10.1101/2022.09.18.508426 — neuroscience — Posted on 2022-09-18

1881 Sympetrum sanguineum Newman, 1833 (Odonata, Anisoptera) - only one species with dimorphic females or two sibling species with identical males?

Anda Felicia, B.

10.1101/2022.09.17.508356 — zoology — Posted on 2022-09-18

1882 Improved models for the relationship between age and the probability of trypanosome infection in female tsetse, Glossina pallidipes Austen

Hargrove, J. W.; Van Sickle, J.

10.1101/2022.09.17.508379 — zoology — Posted on 2022-09-18

1883 Historical biogeography of Cannabis in the Iberian Peninsula: palynological evidence

Rull, V.

10.1101/2022.09.16.508344 — paleontology — Posted on 2022-09-18

1884 Graph construction method impacts variation representation and analyses in a bovine super-pangenome

Leonard, A. S.; Crysnanto, D.; Mapel, X. M.; Bhati, M.; Pausch, H.

10.1101/2022.09.17.508368 — genomics — Posted on 2022-09-18

1885 The Groucho co-repressor inhibits progression through the early transcription elongation checkpoint to repress gene expression

Martinez Quiles, M. L.; Jennings, B. H.

10.1101/2022.09.17.508372 — developmental biology — Posted on 2022-09-18

1886 The histone chaperone NASP maintains H3-H4 reservoirs in the early Drosophila embryo

Tirgar, R.; Davies, J.; Plate, L.; Nordman, J. T.

10.1101/2022.09.16.508322 — developmental biology — Posted on 2022-09-18

1887 Protein Kinase A Activity In The Leading Edge Of Migrating Cells Is Dependent On The Activity Of Focal Adhesion Kinase

Svec, K. V.; Kang, M.; Howe, A. K.

10.1101/2022.09.17.508387 — cell biology — Posted on 2022-09-18

1888 B cell receptor induced IL-10 production from neonatal CD19+CD43- cells depends on STAT5 mediated IL-6 secretion

Sakai, J.; Yang, J.; Chou, C.-K.; Wu, W.; Akkoyunlu, M.

10.1101/2022.09.18.508441 — immunology — Posted on 2022-09-18

1889 Rapid protection of nonhuman primates against Marburg virus disease using a single low-dose VSV-based vaccine

O'Donnell, K. L.; Feldmann, F.; Kaza, B.; Clancy, C. S.; Hanley, P. W.; Fletcher, P.; Marzi, A.

10.1101/2022.09.17.508396 — immunology — Posted on 2022-09-18

1890 Cold-induced Suspension and Resetting of Ca2+ and Transcriptional Rhythms in the Suprachiasmatic Nucleus Neurons

Enoki, R.; Kon, N.; Shimizu, K.; Kobayashi, K.; Yamaguchi, Y.; Nemoto, T.

10.1101/2022.09.18.508357 — neuroscience — Posted on 2022-09-18

1891 Microbial interactions impact the growth response of Clostridioides difficile to antibiotics

Hromada, S.; Venturelli, O. S.

10.1101/2022.09.16.508345 — systems biology — Posted on 2022-09-18

1892 Robust eIF4B levels undermine invasive growth and immune evasion mechanisms in murine triple negative breast cancer models.

Smith, R.; Diba, L. Z. D. Z. D.; Srinivasan, A.; Zollo, R. A.; Ossevoort, T.; He, Q.; Colligan, S. H.; Dolan, M.; Vedire, Y.; Sultana, T.; Venkatesh, M.; Arora, A. P.; Gawlak, S.; Washington, D.; Brackett, C.; Yao, S.; Ebos, J. M. L.; Abrams, S. I.; Barbi, J.; Walker, S. E.

10.1101/2022.09.16.508318 — cancer biology — Posted on 2022-09-18

1893 Development of a 5-FU Modified miR-129 Mimic as a Therapeutic for Non-Small Cell Lung Cancer

Hwang, G.-R.; Yuen, J. G.; Fesler, A.; Farley, H.; Haley, J. D.; Ju, J.

10.1101/2022.09.16.508317 — cancer biology — Posted on 2022-09-18

1894 Mediator Kinase Inhibition Impedes Transcriptional Plasticity and Prevents Resistance to ERK/MAPK-Targeted Therapy in KRAS-Mutant Cancers

Nussbaum, D. P.; Martz, C. A.; Waters, A. M.; Barrera, A.; Rutter, J. C.; Cerda-Smith, C. G.; Stewart, A. E.; Wu, C.; Cakir, M.; Levandowski, C. B.; Kantrowitz, D. E.; McCall, S. J.; Pierobon, M.; Petricoin, E.; Smith, J. J.; Reddy, T. E.; Der, C. J.; Taatjes, D. J.; Wood, K. C.

10.1101/2022.09.17.508384 — cancer biology — Posted on 2022-09-18

1895 Proteogenomic analysis reveals RNA as an important source for tumor-agnostic neoantigen identification correlating with T-cell infiltration

Tretter, C.; de Andrade Kraetzig, N.; Pecoraro, M.; Lange, S.; Seifert, P.; von Frankenberg, C.; Untch, J.; Dreyer, F. S.; Braeunlein, E.; Wilhelm, M.; Zolg, D. P.; Engleitner, T.; Uhrig, S.; Boxberg, M.; Steiger, K.; Slotta-Huspenina, J.; Ochsenreither, S.; von Bubnoff, N.; Bauer, S.; Boerries, M.; Jost, P. J.; Schenck, K.; Dresing, I.; Bassermann, F.; Friess, H.; Reim, D.; Gruetzmann, K.; Pfuetze, K.; Klink, B.; Schrock, E.; Haller, B.; Kuster, B.; Mann, M.; Weichert, W.; Froehling, S.; Rad, R.; Hiltensperger, M.; Krackhardt, A. M.

10.1101/2022.09.17.508207 — cancer biology — Posted on 2022-09-18

1896 PICKLES v3: the updated database of pooled in vitro CRISPR knockout library essentiality screens

Novak, L. C.; Chou, J.; Colic, M.; Bristow, C. A.; Hart, T.

10.1101/2022.09.16.508307 — bioinformatics — Posted on 2022-09-18

1897 Modularly designed protein fragments combine into thousands of active and structurally diverse enzymes

Lipsh-Sokolik, R.; Khersonsky, O.; Schroder, S. P.; de Boer, C.; Hoch, S. Y.; Davies, G. J.; Overkleeft, H. S.; Fleishman, S. J.

10.1101/2022.09.17.508230 — bioengineering — Posted on 2022-09-18

1898 Rigidified Scaffolds for 3-Angstrom Resolution Cryo-EM of Small Therapeutic Protein Targets

Castells-Graells, R.; Meador, K.; Arbing, M. A.; Sawaya, M. R.; Gee, M.; Cascio, D.; Gleave, E. S.; Debreczeni, J. E.; Breed, J.; Phillips, C.; Yeates, T. O.

10.1101/2022.09.18.508009 — biochemistry — Posted on 2022-09-18

1899 Synthesis of Long RNA with a Site-Specific Modification by Enzymatic Splint Ligation

Gamper, H.; McCormick, C.; Tavakoli, S.; Wanunu, M.; Rouhanifard, S. H.; Hou, Y.-M.

10.1101/2022.09.17.508400 — biochemistry — Posted on 2022-09-18

1900 The ClpX protease is essential for removing the CI master repressor and completing prophage induction in Staphylococcus aureus

Thabet, M. A.; Penades, J. R.; Haag, A. F.

10.1101/2022.09.18.507959 — molecular biology — Posted on 2022-09-18

1901 Photocycle characterization of a blue-orange cyanobacteriochrome from Synechococcus sp. PCC 7002

Mihnev, A.; Amtmann, A.; Cogdell, R.; McKenzie, D.

10.1101/2022.09.18.508392 — molecular biology — Posted on 2022-09-18

1902 Parallel multicopy-suppressor screens reveal convergent evolution of phage-encoded single gene lysis proteins

Adler, B. A.; Chamakura, K.; Carion, H.; Krog, J.; Deutschbauer, A. M.; Young, R. F.; Mutalik, V. K.; Arkin, A. P.

10.1101/2022.01.20.477139 — microbiology — Posted on 2022-09-18

1903 Phospholipase B is critical for Cryptococcus neoformans survival in the central nervous system

Hamed, M. F.; Araujo, G.; Munzen, M. E.; Reguera Gomez, M.; Epstein, C.; Lee, H. H.; frases, s.; Martinez, L. R.

10.1101/2022.09.18.508401 — microbiology — Posted on 2022-09-18

1904 A family of novel immune systems targets early infection of nucleus-forming jumbo phages

Li, Y.; Guan, J.; Hareendranath, S.; Crawford, E.; Agard, D. A.; Makarova, K. S.; Koonin, E. V.; Bondy-Denomy, J.

10.1101/2022.09.17.508391 — microbiology — Posted on 2022-09-18

1905 Using Biological Constraints to Improve Prediction in Precision Oncology

Omar, M.; Dinalankara, W.; Mulder, L.; Coady, T.; Zanettini, C.; Imada, E. L.; Younes, L.; Geman, D.; Marchionni, L.

10.1101/2021.05.25.445604 — bioinformatics — Posted on 2022-09-18

1906 Impairment of sugar transport in the vascular system acts on nitrogen remobilisation and nitrogen use efficiency in Arabidopsis.

Hoffmann, B.; Aubry, E.; Marmagne, A.; Dinant, S.; Chardon, F.; Le Hir, R.

10.1101/2022.09.14.507887 — plant biology — Posted on 2022-09-18

1907 Antigen-Specific Antibody Design and Optimization with Diffusion-Based Generative Models for Protein Structures

Luo, S.; Su, Y.; Peng, X.; Wang, S.; Peng, J.; Ma, J.

10.1101/2022.07.10.499510 — bioinformatics — Posted on 2022-09-18

1908 Phylogenomic patterns of divergence and gene flow detail the evolution of reinforcement and hybrid speciation in Phlox wildflowers

Garner, A. G.; Goulet-Scott, B. E.; Hopkins, R.

10.1101/2022.04.15.488502 — evolutionary biology — Posted on 2022-09-18

1909 Plant growers' environmental consciousness may not be enough to mitigate pollinator declines: a questionnaire-based case study in Hungary

Varga-Szilay, Z.; Pozsgai, G.

10.1101/2022.04.07.487523 — ecology — Posted on 2022-09-18

1910 Haloperidol-induced immediate early genes in striatopallidal neurons requires the converging action of cAMP/PKA/DARPP-32 and mTOR pathways

Onimus, O.; Valjent, E.; Fisone, G.; Gangarossa, G.

10.1101/2022.09.10.507436 — neuroscience — Posted on 2022-09-18

1911 X-linked adrenoleukodystrophy patient fibroblast-iPSC-derived astrocytes reveal phenotype-specific metabolic, inflammatory, and microRNA alterations

Parasar, P.; Kaur, N.; Poisson, L.; Singh, J.

10.1101/2022.09.09.507263 — neuroscience — Posted on 2022-09-18

1912 Recording large-scale, cellular-resolution neuronal activity from freely-moving mice

Das, A.; Holden, S.; Borovicka, J.; Icardi, J.; Patel, D.; Patel, R.; Raber, J.; Dana, H.

10.1101/2022.06.01.494442 — neuroscience — Posted on 2022-09-18

1913 Calibration of a Voronoi cell-based model for tumour growth using approximate Bayesian computation

Wang, X.; Jenner, A. L.; Salomone, R.; Drovandi, C.

10.1101/2022.09.13.507714 — systems biology — Posted on 2022-09-18

1914 Leukemia-intrinsic determinants of CAR-T response revealed by iterative in vivo genome-wide CRISPR screening.

Ramos, A.; Koch, C. E.; Liu, Y.; Hellinger, R. D.; Kyung, T.; Abbott, K. L.; Froese, J.; Goulet, D.; Gordon, K. S.; Larson, R. C.; Doench, J. G.; Regev, A.; Vander Heiden, M. G.; Maus, M. V.; Birnbaum, M. E.; Hemann, M.

10.1101/2022.02.15.480217 — cancer biology — Posted on 2022-09-18

1915 Protein structural transitions critically transform the network connectivity and viscoelasticity of RNA-binding protein condensates but RNA can prevent it

Tejedor, A. R.; Sanchez-Burgos, I.; Estevez-Espinosa, M.; Garaizar, A.; Collepardo-Guevara, R.; Ramirez, J.; Espinosa, J. R.

10.1101/2022.03.30.486367 — biophysics — Posted on 2022-09-18

1916 Differential coexistence of multiple genotypes of Ophiocordyceps sinensis in the stromata, ascocarps and ascospores of natural Cordyceps sinensis

Li, Y.-L.; Li, X.-Z.; Yao, Y.-S.; Wu, Z.-M.; Gao, L.; Tan, N.-Z.; Luo, Z.-Q.; Xie, W.-D.; Wu, J.-Y.; Zhu, J.-S.

10.1101/2022.06.20.496766 — molecular biology — Posted on 2022-09-18

1917 Sex-Specific Effects of Psychedelic Drug Exposure on Central Amygdala Reactivity and Behavioral Responding

Effinger, D. P.; Quadir, S. G.; Ramage, M. C.; Cone, M. G.; Herman, M. A.

10.1101/2022.04.28.489882 — neuroscience — Posted on 2022-09-18

1918 A deep learning and digital archaeology approach for mosquito repellent discovery

Wei, J. N.; Vlot, M.; Sanchez-Lengeling, B.; Lee, B. K.; Berning, L.; Vos, M. W.; Henderson, R. W.; Qian, W. W.; Ando, D. M.; Groetsch, K. M.; Gerkin, R. C.; Wiltschko, A. B.; Dechering, K. J.

10.1101/2022.09.01.504601 — bioengineering — Posted on 2022-09-18

1919 Experimental and theoretical aspects of Golden Gate Assembly assays

Strzelecki, P.; Shpiruk, A.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Hebraud, P.; Beyer, N.; Busi, F.; Grange, W.

10.1101/2022.09.09.507109 — molecular biology — Posted on 2022-09-18

1920 The Vibrio Type III Secretion System 2 is not restricted to the Vibrionaceae and encodes differentially distributed repertoires of effector proteins

Jerez, S. A.; Plaza, N.; Bravo, V.; Urrutia, I.; Blondel, C. J.

10.1101/2022.08.23.504659 — microbiology — Posted on 2022-09-18

1921 Bayesian Encoding and Decoding as Distinct Perspectives on Neural Coding

Lange, R. D.; Shivkumar, S.; Chattoraj, A.; Haefner, R. M.

10.1101/2020.10.14.339770 — neuroscience — Posted on 2022-09-18

1922 Selective observation of semi-rigid non-core residues in dynamically complex mutant huntingtin protein fibrils

Matlahov, I.; Boatz, J. C.; van der Wel, P. C. A.

10.1101/2022.05.13.489937 — biophysics — Posted on 2022-09-18

1923 scHiMe: Predicting single-cell DNA methylation levels based on single-cell Hi-C data

Zhu, H.; Liu, T.; Wang, Z.

10.1101/2022.09.13.507815 — bioinformatics — Posted on 2022-09-18

1924 Quantifying the Morphology and Mechanisms of Cancer Progression in 3D in-vitro environments: Integrating Experiments and Multiscale Models

Dimitriou, N. M.; Flores-Torres, S.; Kinsella, J. M.; Mitsis, G. D.

10.1101/2021.11.16.468856 — bioengineering — Posted on 2022-09-18

1925 Insights into the role of lipoteichoic acids and MprF function in Bacillus subtilis

Guyet, A.; Alofi, A.; Daniel, R. A.

10.1101/2021.12.12.472321 — microbiology — Posted on 2022-09-18

1926 Temporal asymmetries and interactions between dorsal and ventral visual pathways during object recognition

Ayzenberg, V.; Simmons, C.; Behrmann, M.

10.1101/2022.09.17.508376 — neuroscience — Posted on 2022-09-18

1927 STAT1 is required to establish but not maintain IFNγ-induced transcriptional memory

Tehrani, S. S.; Mikulski, P.; Abdul-Zani, I.; Mata, J. F.; Siwek, W.; Jansen, L. E. T.

10.1101/2022.09.17.508285 — molecular biology — Posted on 2022-09-17

1928 The cingulo-opercular network is composed of two distinct sub-systems

Gratton, C.; Dworetsky, A.; Adeyemo, B.; Seitzman, B. A.; Smith, D. M.; Petersen, S. E.; Neta, M.

10.1101/2022.09.16.508254 — neuroscience — Posted on 2022-09-18

1929 Adaptive compensation of arcuate fasciculus lateralization in developmental dyslexia

Zhao, J.; Zhao, Y.; Song, Z.; Thiebaut de Schotten, M.; Altarelli, I.; Ramus, F.

10.1101/2022.09.16.508343 — neuroscience — Posted on 2022-09-18

1930 Children's syntax is supported by the maturation of BA44 at 4 years, but of the posterior STS at 3 years of age

Klein, C. C.; Berger, P.; Goucha, T.; Friederici, A. D.; Grosse Wiesmann, C.

10.1101/2022.09.17.508373 — neuroscience — Posted on 2022-09-18

1931 Antigenic characterisation of human monoclonal antibodies for therapeutic use against H7N9 avian influenza virus

Chang, P.; Lukosaityte, D.; Sealy, J. E.; Rijal, P.; Sadeyen, J.-R.; Bhat, S.; Crossley, S.; Daines, R.; Huang, K.-Y. A.; Townsend, A.; Iqbal, M.

10.1101/2022.09.16.508351 — microbiology — Posted on 2022-09-17

1932 Schistosoma mansoni cercarial invadolysin cleaves complement C3 and suppresses proinflammatory cytokine production

Hambrook, J.; Hanington, P. C.

10.1101/2022.09.16.508213 — immunology — Posted on 2022-09-17

1933 ZnO nanoparticles and SWCNT induced general stress response pathway in HepG2 cells at non-cytotoxic doses revealed by RNA sequencing

Mittal, D.; Ali, S. A.; Kaul, G.

10.1101/2022.09.16.508235 — pharmacology and toxicology — Posted on 2022-09-17

1934 Pan-genomic analysis shows hemizygous PTEN loss tumors are associated with immune evasion and poor outcome

Vidotto, T.; M Melo, C.; Lautert-Dutra, W.; Chaves, L. P.; Borges dos Reis, R.; Squire, J.

10.1101/2022.09.16.508308 — cancer biology — Posted on 2022-09-17

1935 Influenza virus membrane fusion is promoted by the endosome-resident phospholipid bis(monoacylglycero)phosphate

Mannsverk, S.; Villamil Giraldo, A. M.; Kasson, P. M.

10.1101/2022.09.16.508338 — biophysics — Posted on 2022-09-17

1936 Computational remodeling of an enzyme conformational landscape for altered substrate selectivity

St-Jacques, A. D.; Rodriguez, J. M.; Eason, M. G.; Foster, S. M.; Khan, S. T.; Damry, A. M.; Goto, N. K.; Thompson, M. C.; Chica, R. A.

10.1101/2022.09.16.508321 — biophysics — Posted on 2022-09-17

1937 On the origin of R2 orientation dependence angle offsets in white matter

Pang, Y.

10.1101/2022.09.16.508261 — biophysics — Posted on 2022-09-17

1938 Splicing-dependent transcriptional activation

Uriostegui-Arcos, M.; Mick, S. T.; Shi, Z.; Rahman, R.; Fiszbein, A.

10.1101/2022.09.16.508316 — molecular biology — Posted on 2022-09-17

1939 Chaperonin activity of Plasmodium prefoldin complex is essential to guard proteotoxic stress response and presents a new target for drug discovery

Shoaib, R.; Kumar, V.; Garg, S.; Saini, M.; Kumari, J.; Maurya, P.; Gupta, A.; Gupta, N.; Singh, H.; Verma, P.; Jain, R.; Biswas, S.; Behl, A.; Abid, M.; Singh, S.

10.1101/2022.09.17.508354 — molecular biology — Posted on 2022-09-17

1940 Global genomic analysis reveals the genetic origin and secondary invasion of fall armyworm in the Eastern hemisphere

Zhang, L.; Li, Z.; Peng, Y.; Liang, X.; Wilson, K.; Chipabika, G.; Schranz, M. E.; Ros, V. I. D.; van Velzen, R.; Xiao, Y.

10.1101/2022.09.16.508260 — molecular biology — Posted on 2022-09-17

1941 In-vitro activity of Cefiderocol against clinical isolates of meropenem-resistant Klebsiella pneumoniae from India.

Borde, K.; Mohammed, K. A.; Sharma, R.; Dass, M. S.; Vedantham, R.; Mathai, D.

10.1101/2022.09.16.508352 — microbiology — Posted on 2022-09-17

1942 Thermophilic carboxylesterases from hydrothermal vents of the volcanic island of Ischia active on synthetic and biobased polymers and mycotoxins

Distaso, M. A.; Chernikova, T. N.; Bargiela, R.; Coscoln, C.; Stogios, P. J.; Gonzalez, J. L.; Lemak, S.; Khusnutdinova, A. N.; Plou, F. J.; Evdokimova, E.; Savchenko, A.; Lunev, E. A.; Yakimov, M. M.; Golyshina, O. V.; Ferrer, M.; Yakunin, A. F.; Golyshin, P. N.

10.1101/2022.09.17.508236 — microbiology — Posted on 2022-09-17

1943 Supervised Machine Learning Enables Geospatial Microbial Provenance

Bhattacharya, C.; Tierney, B. T.; Ryon, K. A.; Bhattacharyya, M.; Hastings, J. J. A.; Basu, S.; Bhattacharya, B.; Bagchi, D.; Mukherjee, S.; Wang, L.; Henaff, E. M.; Mason, C.

10.1101/2022.09.16.508347 — microbiology — Posted on 2022-09-17

1944 Metagenomic analysis of concrete bridge reveals a microbial community dominated by halophilic Bacteria and Archaea

Kiledal, E. A.; Shaw, M.; Polson, S. W.; Maresca, J. A.

10.1101/2022.09.16.508313 — microbiology — Posted on 2022-09-17

1945 CD73 generated extracellular adenosine promotes resolution of neutrophil-mediated tissue injury and restrains metaplasia in pancreatitis

O'Brien, B. J.; Faraoni, E. Y.; Strickland, L. N.; Ma, Z.; Mota, V. Y.; Mota, S. Y.; Chen, X.; Mills, T.; Eltzschig, H. K.; DelGiorno, K. E.; Bailey-Lundberg, J. M.

10.1101/2022.09.17.508367 — immunology — Posted on 2022-09-17

1946 Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates

Rai, S. K.; Khanna, R.; Avni, A.; Mukhopadhyay, S.

10.1101/2022.09.17.508370 — biophysics — Posted on 2022-09-17

1947 scRNA-Seq-based drug repurposing targeting idiopathic pulmonary fibrosis (IPF)

Liu, A.; Lee, J.-H.; Han, N.; Bender, A.

10.1101/2022.09.17.508360 — bioinformatics — Posted on 2022-09-17

1948 A second generation capture panel for cost-effective sequencing of genome regulatory regions in wheat and relatives

Zhang, J.; Debernardi, J. M.; Burguener, G.; Choulet, F.; Paux, E.; O'Connor, L.; Enk, J.; Dubcovsky, J.

10.1101/2022.09.16.508311 — genomics — Posted on 2022-09-17

1949 Genomic deletions and rearrangements in monkeypox virus from the 2022 outbreak, USA

Gigante, C. M.; Plumb, M.; Ruprecht, A.; Zhao, H.; Wicker, V.; Wilkins, K.; Matheny, A.; Khan, T.; Davidson, W.; Sheth, M.; Burgin, A.; Burroughs, M.; Padilla, J.; Lee, J. S.; Dhwani, B.; Hetrick, E. E.; Howard, D. T.; Garfin, J.; Tate, L.; Hubsmith, S. J.; Mendoza, R. M.; Stanek, D.; Gillani, S.; Lee, M.; Mangla, A.; Blythe, D.; Sierra-Patev, S.; Carpenter-Azevedo, K.; Huard, R. C.; Gallagher, G.; Hall, J.; Ash, S.; Kovar, L.; Seabolt, M. H.; Weigand, M. R.; Damon, I.; Satheshkumar, P. S.; McCollum, A. M.; Hutson, C. L.; Wang, X.; Li, Y.

10.1101/2022.09.16.508251 — genomics — Posted on 2022-09-17

1950 Interactions between time on diet, antibiotic treatment, and liver abscess development on the fecal microbiome of beef cattle

Plata, G.; Baxter, N. T.; Hawkins, T. B.; Huntimer, L.; Nagireddy, A.; Susanti, D.; Reinbold, J. B.

10.1101/2022.09.16.508319 — microbiology — Posted on 2022-09-17

1951 Pupillary Dynamics of Mice Performing a Pavlovian Delay Conditioning Task Reflect Reward Predictive Signals.

Yamada, K.; Toda, K.

10.1101/2022.09.15.508189 — animal behavior and cognition — Posted on 2022-09-17

1952 The order Axinellida (Porifera: Demospongiae) in California

Turner, T. L.; Pankey, M. S.

10.1101/2022.03.02.482672 — zoology — Posted on 2022-09-17

1953 Signatures of visuospatial information foraging during learning of complex environments

Barack, D. L.; Bakkour, A.; Shohamy, D.; Salzman, C. D.

10.1101/2021.09.22.461356 — animal behavior and cognition — Posted on 2022-09-17

1954 Shared and distinct genetic etiologies for different types of clonal hematopoiesis

Brown, D. W.; Cato, L. D.; Zhao, Y.; Nandakumar, S. K.; Bao, E. L.; Gardner, E.; DePaulis, A.; Rehling, T.; Song, L.; Yu, K.; Chanock, S. J.; Perry, J. R. B.; Sankaran, V. G.; Machiela, M. J.

10.1101/2022.03.14.483644 — genetics — Posted on 2022-09-17

1955 Adaptive Multi-Objective Control Explains How Humans Make Lateral Maneuvers While Walking

Desmet, D. M.; Cusumano, J. P.; Dingwell, J. B.

10.1101/2022.03.21.485079 — neuroscience — Posted on 2022-09-17

1956 Turnover and replication analysis by isotope labeling (TRAIL) reveals the influence of tissue context on protein and organelle lifetimes

Hasper, J.; Welle, K. A.; Hryhorenko, J.; Ghaemmaghami, S.; Buchwalter, A.

10.1101/2022.04.24.488979 — systems biology — Posted on 2022-09-17

1957 An open-source computational tool for measuring bacterial biofilm morphology and growth kinetics upon one-sided exposure to an antimicrobial source.

Gingichashvili, S.; Steinberg, D.; Sionov, R. V.; Feuerstein, O.; Cohen, N. E.

10.1101/2022.04.20.488818 — bioinformatics — Posted on 2022-09-17

1958 SLC25A46 localizes to sites of mitochondrial fission and fusion and loss of function variants alter the oligomerization states of MFN2 and OPA1

Schuettpelz, J.; Janer, A.; Antonicka, H.; Shoubridge, E.

10.1101/2022.09.16.508286 — cell biology — Posted on 2022-09-17

1959 Identification of a self-renewing muscle satellite cell state by single-cell chromatin accessibility profiling

Okafor, A. E.; Lin, X.; Situ, C.; Wei, X.; Wei, X.; Wu, Z.; Diao, Y.

10.1101/2022.09.16.508339 — cell biology — Posted on 2022-09-17

1960 Small protein modules dictate prophage fates during polylysogeny

Silpe, J. E.; Duddy, O. P.; Hussain, F. A.; Forsberg, K. J.; Bassler, B. L.

10.1101/2022.09.16.508337 — microbiology — Posted on 2022-09-17

1961 In vitro evaluation of immune responses to bacterial hydrogels for the development of living therapeutic materials

Yanamandra, A.; Bhusari, S.; del Campo, A.; Sankaran, S.; Qu, B.

10.1101/2022.09.16.508081 — immunology — Posted on 2022-09-17

1962 Common insecticide affects spatial navigation in bats at environmentally-realistic doses

Herrera, N. I. S.; Jacobo, L. L.; Soto, J. S. V.; Simmons, D.; Faure, P. A.; Welch, K. C.

10.1101/2022.09.14.508021 — pharmacology and toxicology — Posted on 2022-09-17

1963 Cancer cells communicate with macrophages to prevent T cell activation during development of cell cycle therapy resistance

Griffiths, J. I.; Cosgrove, P. A.; Medina Castaneda, E.; Nath, A.; Chen, J.; Adler, F. R.; Chang, J. T.; Khan, Q. J.; Bild, A. H.

10.1101/2022.09.14.507931 — cancer biology — Posted on 2022-09-17

1964 Poly-omic risk scores predict inflammatory bowel disease diagnosis

Arehart, C. H.; Sterrett, J. D.; Garris, R. L.; Quispe-Pilco, R. E.; Gignoux, C. R.; Evans, L. M.; Stanislawski, M. A.

10.1101/2022.09.14.508056 — bioinformatics — Posted on 2022-09-17

1965 Rapid and fully automated blood vasculature analysis in 3D light-sheet image volumes of different organs

Spangenberg, P.; Hagemann, N.; Squire, A.; Foerster, N.; Krauss, S. D.; Qi, Y.; yusuf, A. M.; Wang, J.; Grueneboom, A.; Kowitz, L.; Korste, S.; Totzeck, M.; Cibir, Z.; Tuz, A. A.; Singh, V.; Siemes, D.; Struensee, L.; Engel, D. R.; Ludewig, P.; Melo, L. M. N.; Helfrich, I.; Chen, J.; Gunzer, M.; Hermann, D. M.; Mosig, A.

10.1101/2022.09.14.507895 — bioinformatics — Posted on 2022-09-17

1966 Improve the Protein Complex Prediction with Protein Language Models

Chen, B.; Xie, Z.; Xu, J.; Qiu, J.; Ye, Z.; Tang, J.

10.1101/2022.09.15.508065 — bioinformatics — Posted on 2022-09-17

1967 Signatures 1 and 17 show increased propensity to create mutational hotspots in the human genome

Arnedo, C.; Muinos, F.; Gonzalez-Perez, A.; Lopez-Bigas, N.

10.1101/2022.09.14.507952 — genomics — Posted on 2022-09-17

1968 An island "endemic" born out of hybridization between introduced lineages

Salter, J. F.; Brumfield, R. T.; Faircloth, B. C.

10.1101/2022.09.14.507826 — evolutionary biology — Posted on 2022-09-17

1969 Ancient DNA Reveals China as a Historical Genetic Melting Pot in Tiger Evolution

Sun, X.; Liu, Y.-C.; Tiunov, M. P.; Gimranov, D. O.; Zhuang, Y.; Han, Y.; Driscoll, C. A.; Pang, Y.-H.; Li, C.; Pan, Y.; Velasco, M. S.; Gopalakrishnan, S.; Yang, R.-Z.; Li, B.-G.; Jin, K.; Xu, X.; Uphyrkina, O.; Huang, Y.-Y.; Wu, X.-H.; Gilbert, M. T. P.; O'Brien, S. J.; Yamaguchi, N.; Luo, S.-J.

10.1101/2022.09.14.507899 — evolutionary biology — Posted on 2022-09-17

1970 Parthenogenetic Panagrolaimus species evolve at lower mutation rates, but show increased nucleotide diversity

Villegas, L. I.; Ferretti, L.; Wiehe, T.; Waldvogel, A.-M.; Schiffer, P. H.

10.1101/2022.09.15.508068 — evolutionary biology — Posted on 2022-09-17

1971 Sustainable reference points for multispecies coral reef fisheries

Mason, J. Z.; Cinner, J. E.; MacNeil, M. A.; Graham, N. A.; Hoey, A.; Beger, M.; Brooks, A.; Booth, D.; Edgar, G.; Feary, D.; Ferse, S.; Friedlander, A.; Gough, C.; Green, A.; Mouillot, D.; Polunin, N.; Stuart-Smith, R.; Wantiez, L.; Williams, I.; Wilson, S.; Connolly, S. R.

10.1101/2022.09.14.508013 — ecology — Posted on 2022-09-17

1972 Topographically driven microclimatic gradients shape patterns of forest structure, diversity, and composition at a forest-grassland transition zone

McNichol, B. H.; Wang, R.; Hefner, A.; Helzer, C.; McMahon, S. M.; Russo, S. E.

10.1101/2022.09.15.508106 — ecology — Posted on 2022-09-17

1973 intSDM: A reproducible framework for integrated species distribution models

Mostert, P. S.; Bjorkas, R.; Bruls, A. J. H. M.; Koch, W.; Martin, E. C.

10.1101/2022.09.15.507996 — ecology — Posted on 2022-09-17

1974 Epidermal maintenance of Langerhans cells relies on autophagy-regulated lipid metabolism

Arbogast, F.; Sal-Carro, R.; Boufenghour, W.; Frenger, Q.; Bouis, D.; Filippi de la Palavesa, L.; Fauny, J.-D.; Griso, O.; Puccio, H.; Fima, R.; Huby, T.; Gautier, E. L.; Molitor, A.; Carapito, R.; Bahram, S.; Romani, N.; Clausen, B. E.; Voisin, B.; Mueller, C. G.; Gros, F.; Flacher, V.

10.1101/2022.09.16.507799 — immunology — Posted on 2022-09-17

1975 Cortico-cortical and hippocampo-cortical co-rippling are facilitated by thalamo-cortical spindles and upstates, but not by thalamic ripples

Dickey, C. W.; Verzhbinsky, I. A.; Kajfez, S.; Rosen, B. Q.; Pati, S.; Halgren, E.

10.1101/2022.09.15.507471 — neuroscience — Posted on 2022-09-17

1976 Hippocampal damage causes retrograde amnesia for objects' visual, but not odour, properties

Lacoursiere, S. G.; McAllister, B. B.; Hadikin, C.; Tschetter, W. W.; Lehmann, H.; Sutherland, R. J.

10.1101/2022.09.14.508050 — neuroscience — Posted on 2022-09-17

1977 Detection of neuronal OFF periods as low amplitude neural activity segments

Harding, C. D.; Guillaumin, M. C. C.; Krone, L. B.; Kahn, M. C.; Blanco-Duque, C.; Mikutta, C.; Vyazovskiy, V. V.

10.1101/2022.09.16.508135 — neuroscience — Posted on 2022-09-17

1978 Which visual working memory model accounts best for target representation in the attentional blink?

Wang, S.; Karabay, A.; Akyürek, E.

10.1101/2022.09.15.508098 — neuroscience — Posted on 2022-09-17

1979 Contextual influences of visual perceptual inferences

A-Izzeddin, E. J.; Mattingley, J. B.; Harrison, W. J.

10.1101/2022.09.15.507892 — neuroscience — Posted on 2022-09-17

1980 Unique potential of immature adult-born neurons for the remodeling of CA3 spatial maps

Mugnaini, M.; Trinchero, M. F.; Schinder, A. F.; Piatti, V. C.; Kropff, E.

10.1101/2022.09.14.507576 — neuroscience — Posted on 2022-09-17

1981 Parvalbumin protein controls inhibitory tone in the spinal cord

Qiu, H.; Miraucourt, L.; Petitjean, H.; Davidova, A.; Levesque-Damphousse, P.; Estall, J. L.; Sharif-Naeini, R.

10.1101/2022.09.15.508019 — neuroscience — Posted on 2022-09-17

1982 Fragile X Mental Retardation Protein (FMRP) expression in human nociceptor axons of the spinal dorsal horn-- Implications for RNA targeting and localized translation

Mitchell, M.; Cook, L. F.; Shiers, S.; Tavares-Ferreira, D.; Akopian, A. N.; Dussor, G.; Price, T. J.

10.1101/2022.09.15.508178 — neuroscience — Posted on 2022-09-17

1983 The Role of Students' Situational Interest in Classroom Learning: An Empirical Study based on both Laboratory and Naturalistic Paradigms

Ye, J.; Liu, X.; Wei, J.; Zhang, Y.

10.1101/2022.09.17.508364 — neuroscience — Posted on 2022-09-17

1984 Brain glucose metabolism and ageing: A 5-year longitudinal study in a large PET cohort

Pak, K.; Malen, T.; Santavirta, S.; Shin, S.; Nam, H. Y.; De Maeyer, S.; Nummenmaa, L.

10.1101/2022.09.15.508088 — neuroscience — Posted on 2022-09-17

1985 Observing the self and other in motion modulates the excitability of vestibulocollic reflexes

Nakul, E.; Deroualle, D.; Montava, M.; Lavieille, J.-P.; Lopez, C.

10.1101/2022.09.16.503320 — neuroscience — Posted on 2022-09-17

1986 Dual-Coil Transcranial Magnetic Stimulation Reveals Temporal Dynamics of Bilateral Corticomotor Excitability During Response Inhibition

Ratcliffe, C. E.; McAllister, C. J.; MacDonald, H. J.

10.1101/2022.09.14.507942 — neuroscience — Posted on 2022-09-17

1987 The magnitude of sex differences in host-microbe interactions are time-of-day dependent

Munyoki, S. K.; Goff, J. P.; Mullett, S. J.; Burns, J. K.; Jenkins, A. K.; DePoy, L. M.; Wendell, S. G.; McClung, C. A.; Morrison, K. E.; Jasarevic, E.

10.1101/2022.09.15.508006 — systems biology — Posted on 2022-09-17

1988 Optimal energy and redox metabolism in the cyanobacterium Synechocystis sp. PCC 6803

Kugler, A.; Stensjö, K.

10.1101/2022.09.14.507938 — systems biology — Posted on 2022-09-17

1989 Evaluating the Robustness of Connectivity Methods to Noise for In Silico Drug Repurposing Studies

Tham, N.; Langley, S. R.

10.1101/2022.09.14.508054 — systems biology — Posted on 2022-09-17

1990 Dehydration alters transcript levels in the midgut, likely facilitating rapid rehydration

Holmes, C. J.; Brown, E. S.; Sharma, D.; Warden, M.; Pathak, A.; Payton, B.; Nguyen, Q.; Spangler, A.; Sivakumar, J.; Hendershot, J. M.; Benoit, J. B.

10.1101/2022.09.15.508146 — physiology — Posted on 2022-09-17

1991 DNA methylation supports accelerated biological age in Type 2 Diabetes which can be reversed with pharmacological treatments: Retrospective Cohort Study

Cortez, B. N.; Pan, H.; Aguayo-Mazzucato, C.

10.1101/2022.09.14.507908 — physiology — Posted on 2022-09-17

1992 Tactile stimulation restores inhibited stretch reflex attributable to attenuation of Ia afferents during surprise landing

Konishi, Y.; Yoshii, R.; Takeshita, D.

10.1101/2022.09.14.507870 — physiology — Posted on 2022-09-17

1993 Inflammation-mediated Upregulation of VCAM-1 but not KIM-1 during Acute Kidney Injury to Chronic Kidney Disease Transition

Melchinger, I.; Guo, K.; Guo, J.; Xu, L.

10.1101/2022.09.15.508151 — pathology — Posted on 2022-09-17

1994 Dimethyl fumarate modulates the Duchenne muscular dystrophy disease program following short-term treatment in mdx mice

Timpani, C. A.; Kourakis, S.; Debruin, D. A.; Campelj, D. G.; Pompeani, N.; Dargahi, N.; Bautista, A. P.; Bagaric, R. M.; Ritenis, E. J.; Sahakian, L.; Hafner, P.; Arthur, P. G.; Terrill, J. R.; Apostolopoulos, V.; de Haan, J. B.; Guven, N.; Fischer, D.; Rybalka, E.

10.1101/2022.09.15.508124 — pathology — Posted on 2022-09-17

1995 A new species of Nanhsiungchelys (Testudines: Cryptodira: Nanhsiungchelyidae) from the Upper Cretaceous of Nanxiong Basin, China, and the role of anterolateral processes on the carapace in drag reduction

Ke, Y.; Rahman, I. A.; Song, H.; Hu, J.; Niu, K.; Han, F.

10.1101/2022.09.16.506868 — paleontology — Posted on 2022-09-17

1996 Melanoma-intrinsic NR2F6 activity regulates anti-tumor immunity

Kim, H.; Feng, Y.; Murad, R.; Klepsch, V.; Baier, G.; Ronai, Z. A.

10.1101/2022.09.14.508028 — cancer biology — Posted on 2022-09-17

1997 Illuminating histidine phosphorylation in the pancreatic tumor microenvironment

Hunter, T.; Wahl, G.; Lytle, N.; DelGiorno, K. E.; Shi, Y.; Kaech, S.; Naeem, R.; Luhtala, N.; Hollingsworth, M.

10.1101/2022.09.15.508158 — cancer biology — Posted on 2022-09-17

1998 Oncogenic Kras induces spatiotemporally specific tissue deformation through converting pulsatile into sustained ERK activation

Xin, T.; Gallini, S.; Gonzalez, D.; Gonzalez, L. E.; Regot, S.; Greco, V.

10.1101/2022.09.14.507992 — cancer biology — Posted on 2022-09-17

1999 Optogenetic Instruction of Cell Fate by Temporal Patterning of Mechanobiological Signals

Sampayo, R. G.; Sakamoto, M.; Kumar, S.; Schaffer, D. V.

10.1101/2022.09.14.508003 — cancer biology — Posted on 2022-09-17

2000 Genetically encoded non-canonical amino acids reveal asynchronous dark reversion of chromophore, backbone and side-chains in EL222

Chaudhari, A. S.; Chatterjee, A.; Domingos, C. A. O.; Andrikopoulos, P. C.; Liu, Y.; Andersson, I.; Schneider, B.; Lorenz-Fonfria, V. A.; Fuertes, G.

10.1101/2022.09.16.506679 — biophysics — Posted on 2022-09-17

2001 ReproTox-KG: Toxicology Knowledge Graph for Structural Birth Defects

Evangelista, J. E.; Clarke, D. J.; Xie, Z.; Marino, G. B.; Utti, V.; Ahooyi, T. M.; Jenkins, S. L.; Taylor, D.; Bologa, C. G.; Yang, J. J.; Binder, J. L.; Kumar, P.; Lambert, C. G.; Grethe, J. S.; Wenger, E.; Oprea, T. I.; de Bono, B.; Ma'ayan, A.

10.1101/2022.09.15.508198 — bioinformatics — Posted on 2022-09-17

2002 A Scalable 3D High-Content Imaging Protocol for Measuring a Drug Induced DNA Damage Response Using Immunofluorescent Sub-nuclear γH2AX Spots in Patient Derived Ovarian Cancer Organoids

Keles, H.; Schofield, C. A.; Rannikmae, H.; Edwards, E. E.; Mohamet, L.

10.1101/2022.09.15.508096 — bioinformatics — Posted on 2022-09-17

2003 Development of Machine Learning Model for Pan-cancer Subgroup Identification using Multi-omics Data

Khadirnaikar, S. R.; Shukla, S.; Prasanna, S. R. M.

10.1101/2022.09.15.507989 — bioinformatics — Posted on 2022-09-17

2004 WikiGOA: Gene set enrichment analysis based on Wikipedia and the Gene Ontology

Lubiana, T.; Dias, T. L.; Peixe, D. G.; Nakaya, H. T. I.

10.1101/2022.09.15.508149 — bioinformatics — Posted on 2022-09-17

2005 Dictys: dynamic gene regulatory network dissects developmental continuum with single-cell multi-omics

Wang, L.; Trasanidis, N.; Wu, T.; Dong, G.; Hu, M.; Bauer, D. E.; Pinello, L.

10.1101/2022.09.14.508036 — bioinformatics — Posted on 2022-09-17

2006 Machine learning reveals limited contribution of trans-only encoded variants to the HLA-DQ immunopeptidome by accurate and comprehensive HLA-DQ antigen presentation prediction

Nilsson, J. B.; Kaabinejadian, S.; Yari, H.; Peters, B.; Barra, C.; Gragert, L.; Hildebrand, W.; Nielsen, M.

10.1101/2022.09.14.507934 — bioinformatics — Posted on 2022-09-17

2007 Major cell-types in multiomic single-nucleus datasets impact statistical modeling of links between regulatory sequences and target genes

Leblanc, F. J.; Lettre, G.

10.1101/2022.09.15.507748 — bioinformatics — Posted on 2022-09-17

2008 All-Aqueous Printing of Viscoelastic Droplets in Yield-Stress Fluids

Zhu, J.; Cai, L.

10.1101/2022.09.14.507847 — bioengineering — Posted on 2022-09-17

2009 Machine-Learning Based Optimisation of a Biomimiced Herringbone Microstructure for Superior Aerodynamic Performance.

Patel, R. S.; Akolekar, H. D.

10.1101/2022.09.17.508361 — bioengineering — Posted on 2022-09-17

2010 Adaptive Optical Coherent Raman Imaging of Axons through Mouse Cranial Bone

Lim, J. M.; Yoon, S.; Kim, S.; Choi, Y.; Hong, J. H.; Choi, W.; Cho, M.

10.1101/2022.09.14.507912 — bioengineering — Posted on 2022-09-17

2011 The maize pathogen Ustilago maydis secretes glycoside hydrolases and carbohydrate oxidases directed towards components of the fungal cell wall

Bissaro, B.; Berrin, J.-G.; Grisel, S.; Reyre, J.-L.; Haon, M.; Navarro, D.; Ropartz, D.; Le Gall, S.; Record, E.; Sciara, G.; Tranquet, O.

10.1101/2022.09.16.508353 — biochemistry — Posted on 2022-09-17

2012 Chronic Gq activation of ventral hippocampal neurons and astrocytes differentially affects memory and behavior

Suthard, R. L.; Jellinger, A. L.; Shpokayte, M.; Surets, M.; Pyo, A. Y.; Buzharsky, M. D.; Senne, R. A.; LeBlanc, H.; Ramirez, S.

10.1101/2022.09.15.508157 — animal behavior and cognition — Posted on 2022-09-17

2013 Transcriptome-wide analysis of pseudouridylation in Drosophila melanogaster

Song, W.; Podicheti, R.; Rusch, D. B.; Tracey, D.

10.1101/2022.09.16.507327 — genomics — Posted on 2022-09-17

2014 RECOMBINATION HOTSPOTS IN SOYBEAN

McConaughy, S.; Amundsen, K.; Song, Q.; Pantalone, V.; Hyten, D.

10.1101/2022.09.15.508170 — genetics — Posted on 2022-09-17

2015 Visual-motor integration deficits in 3q29 deletion syndrome

Pollak, R. M.; Burrell, T. L.; Cubells, J. F.; Klaiman, C.; Murphy, M. M.; Saulnier, C. A.; Walker, E. F.; White, S. P.; Mulle, J. G.

10.1101/2022.09.15.508134 — genetics — Posted on 2022-09-17

2016 A large nuclear and mitochondrial sequence dataset for phylogenetic analysis of the hyperdiverse Asterophryinae frogs of the New Guinea region with data on lifestyle, GPS coordinates, elevation, and multispecies communities with accompanying code

Hill, E. C.; Jarman, M.; Fraser, C. J.; Gao, D. F.; Henry, E. R.; Fisher, A. R.; Iova, B.; Allison, A.; Butler, M. A.

10.1101/2022.09.15.508180 — evolutionary biology — Posted on 2022-09-17

2017 The influence of explicit local dynamics on range expansions driven by long-range dispersal

Villiger, N.; Paulose, J.

10.1101/2022.09.15.508171 — evolutionary biology — Posted on 2022-09-17

2018 Geological drivers of diversification in Papuan microhylid frogs

Hill, E. C.; Gao, D. F.; Polhemus, D. A.; Fraser, C. J.; Iova, B.; Allison, A.; Butler, M. A.

10.1101/2022.09.15.508064 — evolutionary biology — Posted on 2022-09-17

2019 The triplet codons across the watershed between the non-living and living matters

Li, D. J.

10.1101/2022.09.14.508044 — evolutionary biology — Posted on 2022-09-17

2020 Demographic History Inference and the Polyploid Continuum

Blischak, P. D.; Sajan, M.; Barker, M. S.; Gutenkunst, R. N.

10.1101/2022.09.15.508148 — evolutionary biology — Posted on 2022-09-17

2021 A biophysical model of viral escape from polyclonal antibodies

Yu, T. C.; Thornton, Z. T.; Hannon, W. H.; DeWitt, W. S.; Radford, C. E.; Matsen, F. A.; Bloom, J. D.

10.1101/2022.09.17.508366 — evolutionary biology — Posted on 2022-09-17

2022 This population doesn't exist: learning the distribution of evolutionary histories with generative adversarial networks

Booker, W. W.; Ray, D. D.; Schrider, D. R.

10.1101/2022.09.17.508145 — evolutionary biology — Posted on 2022-09-17

2023 Whole-genome resequencing data support a single introduction of the invasive white pine sawfly, Diprion similis

Davis, J. S.; Sim, S. B.; Geib, S. M.; Linnen, C. R.

10.1101/2022.09.14.507957 — evolutionary biology — Posted on 2022-09-17

2024 When complex movement yields simple dispersal: behavioural heterogeneity, spatial spread and parasitism in groups of micro-wasps

Burte, V.; Cointe Da Silva, M.; Perez, G.; Mailleret, L.; Calcagno, V.

10.1101/2022.09.14.507936 — ecology — Posted on 2022-09-17

2025 The environmental roots of the relationship between glucocorticoids and body mass in the wild

Lalande, L. D.; Gilot-Fromont, E.; Carbillet, J.; Debias, F.; Duhayer, J.; Gaillard, J.-M.; Lemaitre, J.-F.; Palme, R.; Pardonnet, S.; Pellerin, M.; Rey, B.; Vuarin, P.

10.1101/2022.09.15.508076 — ecology — Posted on 2022-09-17

2026 Somatic nuclear blebbing may indicate proliferating germ cells but does not indicate organismal aging in Caenorhabditis elegans

Fan, Q.; Dong, M.-Q.

10.1101/2022.09.17.508355 — cell biology — Posted on 2022-09-17

2027 Combined multidimensional single-cell protein and RNA profiling dissects the cellular and functional heterogeneity of thymic epithelial cells

Klein, F.; Veiga-Villauriz, C.; Boersch, A.; Maio, S.; Palmer, S.; Zuklys, S.; Calvo-Asensio, I.; Musette, L.; Deadman, M. E.; Dhalla, F.; White, A.; Lucas, B.; Anderson, G.; Hollaender, G. A.

10.1101/2022.09.14.507949 — immunology — Posted on 2022-09-17

2028 MEF2A suppresses replicative stress responses that trigger DDX41-dependent IFN production

Smith, J. R.; Dowling, J. W.; Karp, A.; Schwerk, J.; Savan, R.; Forero, A.

10.1101/2022.09.15.508100 — immunology — Posted on 2022-09-17

2029 Parafoveal and foveal N400 effects in natural sentence reading: Evidence from overlap-corrected fixation-related potentials

Li, N.; Wang, S.; Kornrumpf, F.; Sommer, W.; Dimigen, O.

10.1101/2022.09.14.507765 — neuroscience — Posted on 2022-09-17

2030 Myalgic Encephalomyelitis/Chronic Fatigue Syndrome and fibromyalgia are indistinguishable by their cerebrospinal fluid proteomes

Schutzer, S. E.; Liu, T.; Tsai, C.-F.; Petyuk, V. A.; Schepmoes, A.; Wang, Y.-T.; Weitz, K.; Bergquist, J.; Smith, R.; Natelson, B.

10.1101/2022.09.14.506792 — neuroscience — Posted on 2022-09-17

2031 Perception and Memory Retrieval States are Reflected in Distributed Patterns of Background Functional Connectivity

Li, Y. P.; Wang, Y.; Turk-Browne, N. B.; Kuhl, B. A.; Hutchinson, J. B.

10.1101/2022.09.14.507854 — neuroscience — Posted on 2022-09-17

2032 Improving 3D Edge Detection for Visual Inspection of MRI Coregistration and Alignment

Rorden, C.; Newman-Norlund, R.; Drake, C.; Glen, D. R.; Fridriksson, J.; Hanayik, T.; Taylor, P. A.

10.1101/2022.09.14.507937 — neuroscience — Posted on 2022-09-17

2033 Rapid learning of neural circuitry from holographic ensemble stimulation enabled by model-based compressed sensing

Triplett, M. A.; Gajowa, M.; Antin, B.; Sadahiro, M.; Adesnik, H.; Paninski, L.

10.1101/2022.09.14.507926 — neuroscience — Posted on 2022-09-17

2034 Functional connectivity across the human subcortical auditory system using a Gaussian copula graphical model approach with partial correlations

Sitek, K. R.; Chandra, N.; Sarkar, A.; Chandresekaran, B.

10.1101/2022.09.15.508099 — neuroscience — Posted on 2022-09-17

2035 Acute hyper- and hypoglycemia uncouples the metabolic cooperation between glucose and lactate to disrupt sleep

Carroll, C. M.; Stanley, M.; Raut, R. V.; Constantino, N. J.; Irmen, R. E.; Mitra, A.; Snipes, J. A.; Raichle, M. E.; Holtzman, D. M.; Gould, R. W.; Kishida, K. T.; Macauley, S. L.

10.1101/2022.09.15.507967 — neuroscience — Posted on 2022-09-17

2036 Effects of social presence on behavioural, neural and physiological aspects of empathy for pain

Petereit, P.; Weiblen, R.; Perry, A.; Kraemer, U. M.

10.1101/2022.09.14.507943 — neuroscience — Posted on 2022-09-17

2037 Metabotropic glutamate group II receptor activation in the dorsal striatum suppresses the motivation for cocaine in rats

Khoo, S. Y.-S.; Samaha, A.-N.

10.1101/2022.09.16.507381 — neuroscience — Posted on 2022-09-17

2038 Cell-type-specific roles of inhibitory interneurons in the rehabilitation of auditory cortex after peripheral damage

Kumar, M.; Handy, G.; Kouvaros, S.; Ljungqvist Brinson, L.; Bizup, B.; Doiron, B.; Tzounopoulos, T.

10.1101/2022.09.15.508128 — neuroscience — Posted on 2022-09-17

2039 The Tre1/S1pr1 phospholipid-binding G protein-coupled receptor signaling pathway is required for astrocyte morphogenesis

Chen, J.; Stork, T.; Kang, Y.; Sheehan, A.; Paton, C.; Monk, K.; Freeman, M.

10.1101/2022.09.15.508188 — neuroscience — Posted on 2022-09-17

2040 Genetic Disruption of System xc- Mediated Glutamate Release from Astrocytes Increases Negative-Outcome Behaviors While Preserving Basic Brain Function in Rat

Hess, E. M.; Kassel, S. N.; Simandl, G.; Raddatz, N. J.; Hurley, M. M.; Grzybowski, M.; Klotz, J.; Geurts, A.; Liu, Q.-s.; Choi, S.; Twining, R. C.; Baker, D.

10.1101/2022.09.14.504799 — neuroscience — Posted on 2022-09-17

2041 Age-related complexity of the resting state MEG signals: a multiscale entropy analysis

Makani, A.; Akhavan, A.; Shahbazi, F.; Noruzi, M.; Zare, M.

10.1101/2022.09.14.507986 — neuroscience — Posted on 2022-09-17

2042 Deficiency of Heterogeneous Nuclear Ribonucleoprotein U leads to delayed neurogenesis

Mastropasqua, F.; Oksanen, M.; Soldini, C.; Alatar, S.; Arora, A.; Ballarino, R.; Molinari, M.; Agostini, F.; Poulet, A.; Watts, M. E.; Rabkina, I.; Becker, M.; Li, D.; Anderlid, B.-M.; Isaksson, J.; Remnelius, K. L.; Moslem, M.; Jacob, Y.; Falk, A.; Crosetto, N.; Bienko, M.; Santini, E.; Borgkvist, A.; Bölte, S.; Tammimies, K.

10.1101/2022.09.14.507275 — neuroscience — Posted on 2022-09-17

2043 Efficient coding of natural images in the mouse visual cortex

Bolanos, F.; Orlandi, J. G.; Aoki, R.; Jagadeesh, A.; Gardner, J.; Benucci, A.

10.1101/2022.09.14.507893 — neuroscience — Posted on 2022-09-17

2044 The functional organization of retinal ganglion cell receptive fields across light levels

Ruda, K.; Rudzite, A. M.; Field, G. D.

10.1101/2022.09.15.508164 — neuroscience — Posted on 2022-09-17

2045 Genetic loss of norepinephrine does not alter adult hippocampal neurogenesis in dopamine β-hydroxylase deficient mice

Kapri, D.; Vadodaria, K. C.; Rommelfanger, K. S.; Ogbonmwan, Y. E.; Liles, L. C.; Fernandes-Thomas, K. A.; Salvi, S. S.; Husain, B. F. A.; Weinshenker, D.; Vaidya, V. A.

10.1101/2022.09.14.508040 — neuroscience — Posted on 2022-09-17

2046 Translating DNA origami Nanotechnology to Middle School, High School, and Undergraduate Laboratories

Beshay, P. E.; Kucinic, A.; Wile, N.; Halley, P.; Des Rosiers, L.; Chowdhury, A.; Hall, J. L.; Castro, C. E.; Hudoba, M. W.

10.1101/2022.09.15.508130 — scientific communication and education — Posted on 2022-09-17

2047 The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice

Roussel, J.; LARCHER, R.; SICARD, P.; Bideaux, P.; RICHARD, S.; Thireau, J.; MARMIGERE, F.

10.1101/2022.09.14.507907 — physiology — Posted on 2022-09-17

2048 Quantitative bioactivity signatures of dietary supplements and natural products

Yasgar, A.; Bougie, D.; McKnight, C.; Miller, M.; Peryea, T.; Xia, M.; Shah, P.; Xu, X.; Shinn, P.; Itkin, M.; Lynch, C.; Zakharov, A. V.; Eastman, R.; Kouznetsova, J.; Ngan, D.; Huang, R.; Simeonov, A.

10.1101/2022.09.14.507630 — pharmacology and toxicology — Posted on 2022-09-17

2049 Control of alveolar macrophage differentiation by Siah1a/2 ubiquitin ligases limits carcinogen-induced lung adenocarcinoma

Scortegagna, M.; Du, Y.; Bradley, L. M.; Wang, K.; Ruppin, E.; Murad, R.; Ronai, Z. A.

10.1101/2022.09.14.508032 — cancer biology — Posted on 2022-09-17

2050 Revisiting the bad luck hypothesis: Cancer risk and aging are linked to replication-driven changes to the epigenome

Minteer, C. J.; Thrush, K.; Niimi, P.; Rozowsky, J.; Liu, J.; Frank, M.; McCabe, T.; Hofstatter, E.; Rozenblit, M.; Pusztai, L.; Beckman, K.; Gerstein, M.; Levine, M. E.

10.1101/2022.09.14.507975 — cancer biology — Posted on 2022-09-17

2051 ortho_seqs: A Python tool for sequence analysis and higher order sequence-phenotype mapping

Nafees, S.; Vemuri, V. N.; Woollacott, M.; Solak, A. C.; Logan, P.; McGeever, A.; Yoo, O.; Rice, S. H.

10.1101/2022.09.14.506443 — bioinformatics — Posted on 2022-09-17

2052 Current sequence-based models capture gene expression determinants in promoters but mostly ignore distal enhancers

Karollus, A.; Mauermeier, T.; Gagneur, J.

10.1101/2022.09.15.508087 — bioinformatics — Posted on 2022-09-17

2053 Dynamic Transcriptomic Network Responses to Divergent Acute Exercise Challenges in Young Adults

Lavin, K. M.; Graham, Z. A.; McAdam, J. S.; O'Bryan, S. M.; Drummer, D. J.; Bell, M. B.; Kelley, C. J.; Lixandrao, M. E.; Peoples, B.; Tuggle, S. C.; Seay, R.; Van Keuren-Jensen, K.; Huentelman, M. J.; Pirrotte, P.; Reiman, R.; Alsop, E.; Hutchins, E.; Antone, J.; Bonfitto, A.; Meechoovet, B.; Palade, J.; Talboom, J. S.; Sullivan, A.; Aban, I.; Peri, K.; Broderick, T. J.; Bamman, M. M.

10.1101/2022.09.14.507939 — bioinformatics — Posted on 2022-09-17

2054 TandemAligner: a new parameter-free framework for fast sequence alignment

Bzikadze, A. V.; Pevzner, P. A.

10.1101/2022.09.15.507041 — bioinformatics — Posted on 2022-09-17

2055 A dialysis medium refreshment cell culture set-up for an osteoblast-osteoclast coculture

Vis, M. A. M.; de Wildt, B. W. M.; Hofmann, S.; Ito, K.

10.1101/2022.09.15.508113 — bioengineering — Posted on 2022-09-17

2056 An experimental and theoretical approach to understand the interaction between particles and mucosal tissues

Sverdlov, R.; Davidovich-Pinhas, M.; Cohen, N.; SOSNIK, A.

10.1101/2022.09.15.508137 — bioengineering — Posted on 2022-09-17

2057 Structural and functional changes of pyramidal neurons at the site of an implanted microelectrode array in rat primary motor cortex

Gregory, B. A.; Thompson, C. H.; Salatino, J. W.; Railing, M. J.; Zimmerman, A. F.; Gupta, B.; Williams, K.; Beatty, J. A.; Cox, C. L.; Purcell, E. K.

10.1101/2022.09.15.507997 — bioengineering — Posted on 2022-09-17

2058 A new high-resolution three-dimensional retinal implant: System design and preliminary human results

Yanovitch, L.; Raz-Prag, D.; Hanein, Y.

10.1101/2022.09.14.507901 — bioengineering — Posted on 2022-09-17

2059 Incorporation of bioactive peptides into peptide nanofibrillar hydrogels affects their nanostructure, mechanical properties and biocompatibility

Chong, C. J. H.; Charnley, M.; Ratcliffe, J.; Caballero-Aguilar, L. M.; Moulton, S. E.; Binger, K. J.; Reynolds, N. P.

10.1101/2022.09.15.508197 — bioengineering — Posted on 2022-09-17

2060 Pupillary Dynamics of Mice Performing a Pavlovian Delay Conditioning Task Reflect Reward Predictive Signals.

Yamada, K.; Toda, K.

10.1101/2022.09.15.508189 — animal behavior and cognition — Posted on 2022-09-17

2061 Comparison of Transcriptomic Changes in Younger and Older Multiple Myeloma Patients from the MMRF-CoMMpass Study RNA-Seq Data

Keskin, M.

10.1101/2022.09.14.507921 — genomics — Posted on 2022-09-17

2062 First mitogenome phylogeny of the sun bear Helarctos malayanus reveals a deep split between Indochinese and Sundaic lineages

Kunde, M. N.; Barlow, A.; Klittich, A.; Yakupova, A.; Patel, R. P.; Fickel, J.; Foerster, D. W.

10.1101/2022.09.14.507900 — genomics — Posted on 2022-09-17

2063 Genomic architecture of migration timing in a long-distance migratory songbird

de Greef, E.; Suh, A.; Thorstensen, M. J.; Delmore, K.; Fraser, K. C.

10.1101/2022.09.14.508039 — genomics — Posted on 2022-09-17

2064 Transcriptional patterns of sexual dimorphism and host developmental programs in the model parasitic nematode Heligmosomoides polygyrus

Pollo, S. M. J.; Coria, A. L.; Finney, C. A. M.; Wasmuth, J. D.

10.1101/2022.09.14.508015 — genomics — Posted on 2022-09-17

2065 Widespread convergent evolution of alpha-neurotoxin resistance in African mammals

Drabeck, D.; Holt, J.; McGaugh, S. E.

10.1101/2022.09.14.508034 — evolutionary biology — Posted on 2022-09-17

2066 Differential modularity of the mammalian Engrailed 1 enhancer network directs eccrine sweat gland development

Aldea, D.; Kokalari, B.; Atsuta, Y.; Dingwall, H. L.; Zheng, Y.; Nace, A.; Cotsarelis, G.; Kamberov, Y. G.

10.1101/2022.09.14.508033 — evolutionary biology — Posted on 2022-09-17

2067 The rapid radiation of Bomarea (Alstroemeriaceae: Liliales), driven by the rise of the Andes

Tribble, C. M.; Alzate-Guarin, F.; Gandara, E.; Vartoumian, A.; Burleigh, J. G.; Zenil-Ferguson, R.; Specht, C. D.; Rothfels, C. J.

10.1101/2022.09.15.507859 — evolutionary biology — Posted on 2022-09-17

2068 A continental scale analysis reveals widespread root bimodality

Lu, M.; Wang, S.; Malhotra, A.; Tumber-Davila, S. J.; Weintraub-Leff, S.; McCormack, L.; Wang, X. T.; Jackson, R. B.

10.1101/2022.09.14.507823 — ecology — Posted on 2022-09-17

2069 Determinants of survival and dispersal along the range expansion of a biological invasion

Edeline, E.; Starck, A.; Bennevault, Y.; Paillisson, J.-M.; Petit, E. J.

10.1101/2022.09.14.507789 — ecology — Posted on 2022-09-17

2070 Collection of triatomines from sylvatic habitats by a Chagas-positive, trained scent-detection canine in Texas, USA

Christopher, D.; Curtis-Robles, R.; Hamer, G. L.; Bejcek, J.; Saunders, A.; Roachell, W.; Cropper, T. L.; Hamer, S. A.

10.1101/2022.09.14.508062 — ecology — Posted on 2022-09-17

2071 P3HT-GRAPHENE DEVICE FOR THE RESTORATION OF VISUAL PROPERTIES IN A RAT MODEL OF RETINITIS PIGMENTOSA

Francia, S.; DiMarco, S.; DiFrancesco, M. L.; Ferrari, D. V.; Shmal, D.; Cavalli, A.; Pertile, G.; Attanasio, M.; Maya-Vetencourt, J. F.; Manfredi, G.; Lanzani, G.; Benfenati, F.; Colombo, E.

10.1101/2022.09.14.507903 — neuroscience — Posted on 2022-09-17

2072 The effects of oral supplementation of Japanese sake yeast on anxiety, depressive-like symptoms, oxidative stress, and BDNF changes in chronically stressed adolescent rats

Haghipanah, M.; Saadat, M.; Safarbalou, A.; Budde, T.; Mohamed, W.; Sadat Afraz, E.; Moradikor, N.

10.1101/2022.09.14.507940 — neuroscience — Posted on 2022-09-17

2073 Non-invasive temporal interference electrical stimulation of the human hippocampus

Violante, I. R.; Alania, K.; Cassara, A. M.; Neufeld, E.; Acerbo, E.; Carron, R.; Williamson, A.; Kurtin, D. L.; Rhodes, E.; Hampshire, A.; Kuster, N.; Boyden, E. S.; Pascual-Leone, A.; Grossman, N.

10.1101/2022.09.14.507625 — neuroscience — Posted on 2022-09-17

2074 Modulation of neural variability: Age-related reduction, GABAergic basis, and behavioral implications

Lalwani, P. S.; Polk, T. A.; Garrett, D. D.

10.1101/2022.09.14.507785 — neuroscience — Posted on 2022-09-17

2075 A genomic study of the Japanese population focusing on the glucocorticoid receptor interactome highlights distinct genetic characteristics associated with stress response

Mitsis, T.; Papageorgiou, L.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Kino, T.; Chrousos, G. P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508283 — bioinformatics — Posted on 2022-09-17

2076 Catch me if you can: Capturing extracellular DNA transformation in mixed cultures via Hi-C sequencing

Calderon-Franco, D.; van Loosdrecht, M. C. M.; Abeel, T.; Weissbrodt, D. G.

10.1101/2022.09.16.508255 — bioengineering — Posted on 2022-09-17

2077 Structural variation and eQTL analysis in two experimental populations of chickens divergently selected for feather pecking behavior

Falker-Gieske, C.; Bennewitz, J.; Tetens, J.

10.1101/2022.09.16.508210 — animal behavior and cognition — Posted on 2022-09-17

2078 Screening under infection-relevant conditions reveals chemical sensitivity in multidrug-resistant invasive non-typhoidal Salmonella (iNTS)

Tsai, C. N.; Massicotte, M.-A.; MacNair, C.; Perry, J. N.; Brown, E. D.; Coombes, B. K.

10.1101/2022.09.16.508293 — microbiology — Posted on 2022-09-17

2079 Improved estimates of abortion rates in tsetse (Glossina spp)

Hargrove, J. W.

10.1101/2022.09.15.508167 — zoology — Posted on 2022-09-17

2080 Evolutionary conservation of sequence motifs at sites of protein modification

Dohlman, H.; Li, S.

10.1101/2022.09.15.508132 — systems biology — Posted on 2022-09-17

2081 Monitoring lineages of growing and dividing bacteria reveals an inducible memory of mar operon expression

Guet, C. C.; Bruneaux, L.; oikonomou, P.; Aldana, M.; Cluzel, P.

10.1101/2022.09.16.508303 — systems biology — Posted on 2022-09-17

2082 Leishmania major centrin knock-out parasites alter the Kynurenine- aryl hydrocarbon receptor signaling to produce a pro-inflammatory response

Oljuskin, T.; Azodi, N.; Volpedo, G.; Bhattacharya, P.; Ismail, N.; Hamano, S.; Matlashewski, G.; Satoskar, A.; Gannavaram, S.; Nakhasi, H.

10.1101/2022.09.15.508117 — systems biology — Posted on 2022-09-17

2083 Multi-omics data integration via novel interpretable k-hop graph attention network for signaling network inference

Yuan, R.; Feng, J.; Zhang, H.; Chen, Y.; Payne, P. R.; Li, F.

10.1101/2022.09.16.508281 — systems biology — Posted on 2022-09-17

2084 Can root systems redistribute soil water to mitigate the effects of drought?

Mair, A.; Dupuy, L. X.; Ptashnyk, M.

10.1101/2022.09.15.508112 — systems biology — Posted on 2022-09-17

2085 An integrase toolbox to record gene-expression during plant development.

Guiziou, S.; Maranas, C. J.; Chu, J. C.; Nemhauser, J. L.

10.1101/2022.09.16.508262 — synthetic biology — Posted on 2022-09-17

2086 Differences in self-reported benefits for student-artist versus faculty experiences in a virtual artist-in-residence program.

Cuevas, S.; Liu, Q.; Qian, H.; Joffe, M. E.; Calvitti, K.; Schladt, M.; Skaar, E. P.; Oliver, K. H.

10.1101/2022.09.14.507965 — scientific communication and education — Posted on 2022-09-17

2087 Factors associated with misdiagnosis of hospitalized patients in general hospitals of Central Uganda

Katongole, S. P.; Akweongo, P.; Anguyo Onzima DDM, R.; Kasozi, D. E.; Adomah-Afari, A.

10.1101/2022.09.16.508252 — scientific communication and education — Posted on 2022-09-17

2088 Utilizing Evolutionary Conservation to Detect Deleterious Mutations and Improve Genomic Prediction in Cassava

Long, E. M.; Romay, M. C.; Buckler, E. S.; Robbins, K.

10.1101/2022.09.16.508169 — plant biology — Posted on 2022-09-17

2089 An R-R-type MYB transcription factor promotes nonclimacteric pepper fruit ripening pigmentation

Ning, Z.; Song, J.; Chen, C.; Sun, B.; Zhang, S.; Cai, Y.; Zheng, X.; Cao, B.; Chen, G.; Jin, D.; Li, B.; Bian, J.; Lei, J.; He, H.; Zhu, Z.

10.1101/2022.09.15.507774 — plant biology — Posted on 2022-09-17

2090 Brassinosteroid gene regulatory networks at cellular resolution

Nolan, T. M.; Vukasinovic, N.; Hsu, C.-W.; Zhang, J.; Vanhoutte, I.; Shahan, R.; Taylor, I. W.; Greenstreet, L.; Heitz, M.; Wang, P.; Szekely, P.; Brosnan, A.; Yin, Y.; Schiebinger, G.; Ohler, U.; Russinova, E.; Benfey, P. N.

10.1101/2022.09.16.508001 — plant biology — Posted on 2022-09-17

2091 Combining historical agricultural and climate datasets sheds new light on early 20th century barley performance

Raymond, J.; Mackay, I.; Penfield, S.; Lovett, A.; Philpott, H.; Dorling, S.

10.1101/2022.09.14.507767 — plant biology — Posted on 2022-09-17

2092 An updated evolutionary and structural study of TBK1 reveals highly conserved motifs as potential pharmacological targets in neurodegenerative diseases.

Papageorgiou, L.; Mangana, E.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Chrousos, G. P.; Exarchos, T. P.; Vlamos, P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508274 — bioinformatics — Posted on 2022-09-17

2093 Female chacma baboons modulate their sexual receptivity in response to male coercion

Darmis, F.; Huchard, E.; Cowlishaw, G.; Carter, A. J.

10.1101/2022.09.16.508123 — animal behavior and cognition — Posted on 2022-09-17

2094 Effects of Oxytocin Receptor Blockade on Dyadic Social Behavior in Monogamous and Non-Monogamous Eulemur

Grebe, N.; Sheikh, A.; Ohannessian, L.; Drea, C. M.

10.1101/2022.09.14.507945 — animal behavior and cognition — Posted on 2022-09-17

2095 Bet hedging is not sufficient to explain intraspecific variation in germination patterns of a winter annual plant

Siegmund, G.-F.; Moeller, D. A.; Eckhart, V. M.; Geber, M. A.

10.1101/2022.09.15.508102 — ecology — Posted on 2022-09-17

2096 Rnf20 shapes the endothelial control of heart morphogenesis and function

Kessler, L.; Gao, R.; Tetik-Elsherbiny, N.; Lityagina, O.; Zhailauova, A.; Ren, Y.; Trogisch, F. A.; Cordero, J.; Dou, Y.; Wang, Y.; Chichelnitskiy, E.; Kraske, J.; Schaefer, P.; Wu, C.-C.; Barreto, G.; Potente, M.; Wieland, T.; Ola, R.; Heineke, J.; Dobreva, G.

10.1101/2022.09.16.508288 — developmental biology — Posted on 2022-09-17

2097 Genotypic variation in tolerance to salinity in Pakistani okra (Abelmoschus esculentus L.) varieties as assessed at seed germination, seedling growth and biochemical characters

Ullah, H.; Jan, T.; Wahid, F.; Zahoor, M.; Uddin, S.; Bibi, S.

10.1101/2022.09.14.508060 — developmental biology — Posted on 2022-09-17

2098 The Slingshot phosphatase 2 is required for acrosome biogenesis during spermatogenesis in mice

Xu, K.; Su, X.; Fang, K.; Lv, Y.; Lu, G.; Chan, W.; Chen, Z.-J.; Ma, J.; Liu, H.

10.1101/2022.09.15.508144 — developmental biology — Posted on 2022-09-17

2099 Hybridization led to a rewired pluripotency network in the allotetraploid Xenopus laevis

Phelps, W. A.; Hurton, M. D.; Ayers, T. N.; Carlson, A. E.; Rosenbaum, J. C.; Lee, M. T.

10.1101/2022.09.14.507817 — developmental biology — Posted on 2022-09-17

2100 An intragenic FAT1 regulatory element deleted in muscular dystrophy patients drives muscle and mesenchyme expression during development

Caruso, N.; Zimmermann, A. K.; Nigam, T.; Becker, C.; Lipson, K.; Helmbacher, F.

10.1101/2022.09.14.507898 — developmental biology — Posted on 2022-09-17

2101 Large scale production of human blastoids amenable to modeling blastocyst development and maternal-fetal crosstalk

Yu, L.; Ezashi, T.; Wei, Y.; Duan, J.; Logsdon, D.; Zhan, L.; Nahar, A.; Arteaga, C. P.; Liu, L.; Stobbe, C.; Katz-Jaffe, M.; Schoolcraft, W. B.; Wang, L.; Tan, T.; Hon, G. C.; Yuan, Y.; Wu, J.

10.1101/2022.09.14.507946 — developmental biology — Posted on 2022-09-17

2102 Neuromodulatory silencing of nerve terminals

Cook, D. C.; Ryan, T. A.

10.1101/2022.09.16.508300 — neuroscience — Posted on 2022-09-17

2103 GPCR Signaling Promotes a Stress-induced Genetic Program for Phenoptosis in C. elegans

Wang, C.; Long, Y.; Wang, B.; Zhang, C.; Ma, D. K.

10.1101/2022.09.16.508223 — developmental biology — Posted on 2022-09-17

2104 Cardiomyocyte ploidy is dynamic during postnatal development and varies across genetic backgrounds

Swift, S. K.; Purdy, A. L.; Kolell, M. E.; Flinn, M. A.; Lahue, C.; Buddell, T.; Akins, K. A.; Foster, P.; O'Meara, C. C.; Rau, C.; Patterson, M.

10.1101/2022.09.15.508152 — developmental biology — Posted on 2022-09-17

2105 Morphological and temporal variation in early embryogenesis contributes to species divergence in Malawi cichlid fishes

Marconi, A.; Yang, C.; McKay, S.; Santos, M. E.

10.1101/2022.09.16.508246 — developmental biology — Posted on 2022-09-17

2106 Toward Improving Immunotolerance for Stem Cell-Derived Islets

Zhou, Q.; Li, H.; Gerace, D.; Nikolskly, I.; Wang, X.; Kenty-Ryu, J.; Zhang, J.; Hinderhofer, M.; Robinson, E.; Melton, D. A.

10.1101/2022.09.15.508091 — developmental biology — Posted on 2022-09-17

2107 Neuroprotective tissue adaptation induced by IL-12 attenuates CNS inflammation

Andreadou, M.; Ingelfinger, F.; De Feo, D.; Friebel, E.; Tuzlak, S.; Cramer, T. M. L.; Schreiner, B.; Eede, P.; Schneeberger, S.; Geesdorf, M.; Ridder, F.; Welsh, C. A.; Kirschenbaum, D.; Tyagarajan, S. K.; Greter, M.; Heppner, F. L.; Mundt, S.; Becher, B.

10.1101/2022.09.14.506749 — immunology — Posted on 2022-09-16

2108 Direct inference and control of genetic population structure from RNA sequencing data

Fachrul, M.; Karkey, A.; Shakya, M.; Judd, L.; Harshegyi, T.; Sim, K. S.; Tonks, S.; Dongol, S.; Shrestha, R.; Salim, A.; STRATAA study group, ; Baker, S.; Pollard, A. J.; Khor, C. C.; Dolecek, C.; Basnyat, B.; Dunstan, S. J.; Holt, K. E.; Inouye, M.

10.1101/2022.09.16.508259 — bioinformatics — Posted on 2022-09-16

2109 Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance

Cabral-Costa, J. V.; Vicente-Gutierrez, C.; Agulla, J.; Lapresa, R.; Elrod, J. W.; Almeida, A.; Bolanos, J. P.; Kowaltowski, A. J.

10.1101/2022.09.16.507284 — biochemistry — Posted on 2022-09-16

2110 A Coarse-Grained Molecular Dynamics Investigation on Spontaneous Binding of Aβ9-40 Fibril with Cholesterol-mixed DPPC Bilayer

Agrawal, N.; Skelton, A. A.; Parisini, E.

10.1101/2022.09.16.508209 — biochemistry — Posted on 2022-09-16

2111 Notch directs telencephalic development and neuron fate determination by regulating miRNA levels

Han, J. S.; Fishman-Williams, E. K.; Decker, S. C.; Hino, K. K.; Reyes, R. V.; Brown, N. L.; Simo, S.; La Torre, A.

10.1101/2022.09.16.508220 — developmental biology — Posted on 2022-09-16

2112 Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation

Theobald, H.; Bejarano, D.; Katzmarski, N.; Haub, J.; Schulte-Schrepping, J.; Yu, J.; Bassler, K.; Osei-Sarpong, C.; Piattini, F.; Vornholz, L.; Xu, X.; Sheoran, S.; Al Jawazneh, A.; Chakarov, S.; Haendler, K.; Brown, G. D.; Williams, D.; Bosurgi, L.; Ginhoux, F.; Ruland, J.; Beyer, M. D.; Greter, M.; Kopf, M.; Schultze, J. L.; Schlitzer, A.

10.1101/2022.09.15.505390 — immunology — Posted on 2022-09-16

2113 Feature similarity gradients detect alterations in the neonatal cortex associated with preterm birth

Galdi, P.; Blesa Cabez, M.; Farrugia, C.; Vaher, K.; Williams, L. Z. J.; Sullivan, G.; Stoye, D. Q.; Quigley, A. J.; Makropoulos, A.; Thrippleton, M. J.; Bastin, M. E.; Richardson, H.; Whalley, H. C.; Edwards, D.; Bajada, C. J.; Robinson, E. C.; Boardman, J. P.

10.1101/2022.09.15.508133 — neuroscience — Posted on 2022-09-16

2114 Advanced Feedback Enhances Sensorimotor Adaptation

Wang, T.; Avraham, G.; Tsay, J.; Thummala, T.; Ivry, R. B.

10.1101/2022.09.14.508027 — neuroscience — Posted on 2022-09-16

2115 Antiviral effect of thiazolides relies on mitochondrial mild uncoupling

Hammad, N.; Ransy, C.; Pinson, B.; Talmasson, J.; Brechot, C.; Bouillaud, F.; Rossignol, J.-F.

10.1101/2022.09.16.508272 — biochemistry — Posted on 2022-09-16

2116 Formation of the active Hermes transpososome is driven by asymmetric DNA binding of BED domains

Lannes, L.; Furman, C. M.; Hickman, A. B.; Dyda, F.

10.1101/2022.09.16.508221 — biochemistry — Posted on 2022-09-16

2117 Characterizing the Resolution and Throughput of the Apollo Direct Electron Detector

Peng, R.; Fu, X.; Mendez, J. H.; Randolph, P. S.; Bammes, B. E.; Stagg, S. M.

10.1101/2022.09.16.508245 — biochemistry — Posted on 2022-09-16

2118 A 16p11.2 deletion mouse model displays quantitatively and qualitatively different behaviours in sociability and social novelty over short- and long-term observation.

Rusu, A.; Chevalier, C.; de Chaumont, F.; Nalesso, V.; Brault, V.; Herault, Y.; Ey, E.

10.1101/2022.09.16.508234 — animal behavior and cognition — Posted on 2022-09-16

2119 Insights into the molecular mechanism of translation inhibition by the ribosome-targeting antibiotic thermorubin.

Paranjpe, M. N.; Marina, V. I.; Grachev, A. A.; Maviza, T. P.; Tolicheva, O. A.; Paleskava, A.; Osterman, I. A.; Sergiev, P. V.; Konevega, A. L.; Polikanov, Y. S.; Gagnon, M. G.

10.1101/2022.09.15.508020 — molecular biology — Posted on 2022-09-16

2120 CTCF and R-loops are boundaries of cohesin-mediated DNA looping

Zhang, H.; Shi, Z.; Kim, Y.; Yu, H.; Bai, X.-c.; Finkelstein, I. J.

10.1101/2022.09.15.508177 — molecular biology — Posted on 2022-09-16

2121 Intermittent fasting has a diet-specific impact on the gut microbiota and colonic mucin O-glycosylation of mice

Gamage, H. K. A. H.; Sathili, A. M. M.; Nishtala, K.; Chong, R. W. W.; Packer, N. H.; Paulsen, I. T.

10.1101/2022.09.15.508181 — microbiology — Posted on 2022-09-16

2122 Molecular Acclimation of Halobacterium salinarum to Halite Brine Inclusions

Favreau, C.; Tribondeau, A.; Marugan, M.; Guyot, F.; Alpha-Bazin, B.; Marie, A.; Puppo, R.; Dufour, T.; Huguet, A.; Zirah, S.; Kish, A.

10.1101/2022.09.16.508090 — microbiology — Posted on 2022-09-16

2123 Production and characterisation of stabilised PV-3 virus-like particles using Pichia pastoris

Sherry, L.; Grehan, K.; Swanson, J. J.; Bahar, M. W.; Porta, C.; Fry, E. E.; Stuart, D. I.; Rowlands, D.; Stonehouse, N. J.

10.1101/2022.09.16.508282 — microbiology — Posted on 2022-09-16

2124 Enrichment and application of bacterial sialic acids containing polymers from the extracellular polymeric substances of Candidatus Accumulibacter

Tomas-Martinez, S.; Chen, L. M.; Pabst, M.; Weissbrodt, D. G.; van Loosdrecht, M. C. M.; Lin, Y.

10.1101/2022.09.16.508216 — microbiology — Posted on 2022-09-16

2125 Pathway elucidation and microbial synthesis of proaporphine and bis-benzylisoquinoline alkaloids from sacred lotus (Nelumbo nucifera)

Pyne, M.; Martin, V.

10.1101/2022.09.16.508242 — synthetic biology — Posted on 2022-09-16

2126 Semantic and population analysis of the genetic targets related to COVID-19 and its association with genes and diseases

Papageorgiou, L.; Papakonstantinou, E.; Diakou, I.; Pierouli, K.; Dragoumani, K.; Bacopoulou, F.; Chrousos, G. P.; Eliopoulos, E.; Vlachakis, D.

10.1101/2022.09.16.508278 — bioinformatics — Posted on 2022-09-16

2127 Purification and biochemical analysis of native AMPA receptors from three different mammalian species

Rao, P.; Gouaux, E.

10.1101/2022.09.16.508249 — biochemistry — Posted on 2022-09-16

2128 Enterovirus-cardiomyocyte interactions: impact of terminally deleted genomic RNAs on viral and host functions

Bouin, A.; Vu, M. N.; Al-Hakeem, A.; Tran, G. P.; Nguyen, J. H. C.; Semler, B. L.

10.1101/2022.09.15.508200 — microbiology — Posted on 2022-09-16

2129 Evaluation of different strategies for efficient sporulation and germination of the MICP bacterium Lysinibacillus sphaericus strain MB284 (ATCC 13805)

Rahmaninezhad, S. A.; Farnam, A. Y.; Schauer, C. L.; Raeisi Najafi, A.; Sales, C. M.

10.1101/2022.09.15.508202 — microbiology — Posted on 2022-09-16

2130 Leishmania mexicana Centrin Knock out Parasites Promote M1-polarizing Metabolic Changes

Volpedo, G.; Oljuskin, T.; Azodi, N.; Hamano, S.; Matlashewski, G.; Gannavaram, S.; Nakhasi, H.; Satoskar, A. R.

10.1101/2022.09.16.508215 — microbiology — Posted on 2022-09-16

2131 Protease-independent production of poliovirus virus-like particles in Pichia pastoris: Implications for efficient vaccine development and insights into capsid assembly.

Sherry, L.; Swanson, J. J.; Grehan, K.; Xu, H.; Uchida, M.; Jones, I. M.; Stonehouse, N. J.; Rowlands, D. J.

10.1101/2022.09.16.508263 — microbiology — Posted on 2022-09-16

2132 Transcriptional units form the elementary constraining building blocks of the bacterial chromosome

Bignaud, A.; Cockram, C.; Allemand, E.; Mozziconacci, J.; Espeli, O.; Koszul, R.

10.1101/2022.09.16.507559 — microbiology — Posted on 2022-09-16

2133 Omicron sublineage BA.2.75.2 exhibits extensive escape from neutralising antibodies

Sheward, D. J.; Kim, C.; Fischbach, J.; Muschiol, S.; Ehling, R. A.; Björkström, N. K.; Karlsson Hedestam, G. B.; Reddy, S. T.; Albert, J.; Peacock, T. P.; Murrell, B.

10.1101/2022.09.16.508299 — immunology — Posted on 2022-09-16

2134 Functional unit and regulatory mechanisms of supergene in female-limited Batesian mimicry of Papilio polytes

Komata, S.; Yoda, S.; KonDo, Y.; Shinozaki, S.; Tamai, K.; Fujiwara, H.

10.1101/2022.02.21.480812 — genetics — Posted on 2022-09-16

2135 Sumoylation is largely dispensable for normal growth but facilitates heat tolerance in yeast

Moallem, M.; Akhter, A.; Burke, G. L.; Babu, J.; Bergey, B. G.; McNeil, J. B.; Baig, M. S.; Rosonina, E.

10.1101/761759 — molecular biology — Posted on 2022-09-16

2136 Genome characterization of monkeypox cases detected in India: Identification of three sub clusters among A.2 lineage

10.1101/2022.09.16.507742 — microbiology — Posted on 2022-09-16

2137 SARS-CoV-2 and HSV-1 Induce Amyloid Aggregation in Human CSF

Christ, W.; Kapell, S.; Mermelekas, G.; Evertsson, B.; Sork, H.; Bazaz, S.; Gustafsson, O.; Sobkowiak, M. J.; Cardenas, E. I.; Villa, V.; Ricciarelli, R.; Sandberg, J. K.; Bergquist, J.; Sturchio, A.; Svenningsson, P.; Malm, T.; Espay, A. J.; Pernemalm, M.; Linden, A.; Klingstrom, J.; EL Andaloussi, S.; Ezzat, K.

10.1101/2022.09.15.508120 — microbiology — Posted on 2022-09-16

2138 Imprinted SARS-CoV-2 humoral immunity induces converging Omicron RBD evolution

10.1101/2022.09.15.507787 — immunology — Posted on 2022-09-16

2139 Deep6: Classification of Metatranscriptomic Sequences into Cellular Empires and Viral Realms Using Deep Learning Models

Finke, J. F.; Kellogg, C.; Suttle, C. A.

10.1101/2022.09.13.507819 — bioinformatics — Posted on 2022-09-16

2140 Genotypic sex shapes maternal care in the African Pygmy mouse, Mus minutoides

Heitzmann, L. D.; Challe, M.; Perez, J.; Castell, L.; Galibert, E.; Martin, A.; Valjent, E.; Veyrunes, F.

10.1101/2022.04.05.487174 — evolutionary biology — Posted on 2022-09-16

2141 Body mass change over winter is consistently sex-specific across roe deer populations

Hewison, A. J. M.; Bonnot, N.; Gaillard, J.-M.; Kjellander, P.; Lemaitre, J.-F.; Morellet, N.; Pellerin, M.

10.1101/2022.09.09.507329 — ecology — Posted on 2022-09-16

2142 Revising the global biogeography of plant life cycles

Poppenwimer, T.; Mayrose, I.; DeMalach, N.

10.1101/2022.09.13.507878 — ecology — Posted on 2022-09-16

2143 Origins of monkeypox viruses and their strains circulating in 2022

Chen, J.-M.; Gong, H.; Chen, R.-X.; Sun, M.-H.; Yufei, J.; Li, G.-H.; Tan, S.-M.; Sun, Y.-X.

10.1101/2022.09.07.506685 — microbiology — Posted on 2022-09-16

2144 The contrasting roles of nitric oxide drive microbial community organization as a function of oxygen presence

Wilbert, S. A.; Newman, D. K.

10.1101/2021.12.09.472001 — microbiology — Posted on 2022-09-16

2145 Immune, endothelial and neuronal network map in human lymph node and spleen

Currlin, S.; Nick, H.; Jorgensen, M.; Nick, J.; Brusko, M.; Hakimian, H.; Penaloza-Aponte, J.; Rodriguez, N.; Medina-Serpas, M.; Yang, M.; Seifert, R.; Kusmartseva, I.; Brusko, T.; Otto, K.; Posgai, A.; Wasserfall, C.; Atkinson, M. A.

10.1101/2021.10.20.465151 — immunology — Posted on 2022-09-16

2146 Residual dynamics resolves recurrent contributions to neural computation

Galgali, A. R.; Sahani, M.; Mante, V.

10.1101/2021.07.19.452951 — neuroscience — Posted on 2022-09-16

2147 Planar aggregation of the influenza viral fusion peptide alters membrane structure and hydration, promoting poration.

Rice, A.; Haldar, S.; Wang, E.; Blank, P. S.; Akimov, S. A.; Galimzyanov, T. R.; Pastor, R. W.; Zimmerberg, J.

10.1101/2021.08.09.455689 — biophysics — Posted on 2022-09-16

2148 scHiMe: Predicting single-cell DNA methylation levels based on single-cell Hi-C data

Zhu, H.; Liu, T.; Wang, Z.

10.1101/2022.09.13.507815 — bioinformatics — Posted on 2022-09-16

2149 OpenPBTA: An Open Pediatric Brain Tumor Atlas

Shapiro, J. A.; Gaonkar, K. S.; Savonen, C. L.; Spielman, S. J.; Bethell, C. J.; Jin, R.; Rathi, K. S.; Zhu, Y.; Egolf, L. E.; Farrow, B. K.; Miller, D. P.; Yang, Y.; Koganti, T.; Noureen, N.; Koptyra, M. P.; Duong, N.; Kraya, A. A.; Kline, C. N.; Guo, Y.; Storm, P. B.; Nazarian, J.; Mack, S. C.; Raman, P.; Zheng, S.; Madsen, P. J.; Van Kuren, N.; Robins, S.; Huang, X.; Waanders, A. J.; Kim, J.; Hanson, D.; Koschmann, C. J.; Diskin, S. J.; Lulla, R. R.; Brown, M. A.; Wong, J.; Mason, J. L.; Scolaro, L.; Kim, M. C.; Xie, H. M.; Rood, B. R.; Cole, K. A.; Margol, A. S.; Vaksman, Z.; Kaufman, R. S

10.1101/2022.09.13.507832 — genomics — Posted on 2022-09-16

2150 Regenerative hallmarks of aging: Insights through the lens of Pleurodeles waltl

Tsissios, G.; Theodoroudis-Rapp, G.; Chen, W.; Sallese, A.; Smucker, B.; Ernst, L.; Chen, J.; Xu, Y.; Ratvasky, S.; Wang, H.; Del Rio-Tsonis, K.

10.1101/2022.09.13.507508 — developmental biology — Posted on 2022-09-16

2151 The human placenta shapes the phenotype of decidual macrophages.

Vondra, S.; Hoebler, A.-L.; Lackner, A. I.; Raffetseder, J.; Mihalic, Z. N.; Vogel, A.; Saleh, L.; Kunihs, V.; Haslinger, P.; Wahrmann, M.; Husslein, H.; Oberle, R.; Kargl, J.; Haider, S.; Latos, P.; Schabbauer, G.; Knoefler, M.; Ernerudh, J.; Pollheimer, J.

10.1101/2022.03.29.486171 — immunology — Posted on 2022-09-16

2152 Chronic stress exposure alters the gut barrier: sex-specific effects on microbiota and jejunum tight junctions

Doney, E.; Dion-Albert, L.; Coulombe-Rozon, F.; Osbourne, N.; Bernatchez, R.; Paton, S. E. J.; Kaufmann, F. N.; Agomma, R. O.; Solano, J. L.; Gaumond, R.; Dudek, K. A.; Szyszkowicz, J. K.; Signature Consortium, ; Lebel, M.; Doyen, A.; Durand, A.; Lavoie-Cardinal, F.; Audet, M.-C.; Menard, C.

10.1101/2022.09.13.507821 — neuroscience — Posted on 2022-09-16

2153 Characterization of a novel gene-environment-based animal model to study resilience and susceptibility to PTSD and co-morbid depression

Iglesias, L. P.; Coelho, A. A.; da Silva, N. R.; Muller, H. K.; Moreira, F. A.; Wegener, G.; Joca, S.

10.1101/2022.09.14.507883 — neuroscience — Posted on 2022-09-16

2154 Coherently Remapping Toroidal Cells But Not Grid Cells are Responsible for Path Integration in Virtual Agents

Schoyen, V. S.; Pettersen, M. B.; Holzhausen, K.; Fyhn, M.; Malthe-Sorenssen, A.; Lepperod, M. E.

10.1101/2022.08.18.504379 — neuroscience — Posted on 2022-09-16

2155 Unbalanced response to growth variations reshapes the cell fate decision landscape

Zhu, J.; Chu, P.; Fu, X.

10.1101/2022.09.13.507864 — systems biology — Posted on 2022-09-16

2156 Mobility of the human foot's medial arch enables upright bipedal locomotion

Welte, L.; Holowka, N. B.; Arndt, T.; Kelly, L. A.; Rainbow, M. J.

10.1101/2022.09.13.507861 — physiology — Posted on 2022-09-16

2157 Reconstituted depolarization-induced Ca2+ release platform for skeletal muscle disease mutation validation and drug discovery

Murayama, T.; Kurebayashi, N.; Numaga-Tomita, T.; Kobayashi, T.; Okazaki, S.; Yamashiro, K.; Nakada, T.; Mori, S.; Ishida, R.; Kagechika, H.; Yamada, M.; Sakurai, T.

10.1101/2022.06.29.498090 — physiology — Posted on 2022-09-16

2158 Pathology of African Swine Fever in wild boar naturally infected with German virus variants

Sehl-Ewert, J.; Deutschmann, P.; Breithaupt, A.; Blome, S.

10.1101/2022.09.14.507889 — pathology — Posted on 2022-09-16

2159 Topological Links in Predicted Protein Complex Structures Reveal Limitations of AlphaFold

Hou, Y.; Xie, T.; He, L.; Tao, L.; Huang, J.

10.1101/2022.09.14.507881 — bioinformatics — Posted on 2022-09-16

2160 Seq2Neo: a comprehensive pipeline for cancer neoantigen im-munogenicity prediction

Diao, K.; Chen, J.; Wu, T.; Wang, X.; Wang, G.; Sun, X.; Zhao, X.; Wu, C.; Wang, J.; Yao, H.; Gerarduzzi, C.; Liu, X.-S.

10.1101/2022.09.14.507872 — bioinformatics — Posted on 2022-09-16

2161 Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles

Jan, N.-J.; Lee, P.-Y.; Wallace, J.; Iasella, M.; Gogola, A.; Sigal, I. A.

10.1101/2022.09.13.507860 — bioengineering — Posted on 2022-09-16

2162 Regenerative MRL/MpJ Tendon Cells Exhibit Sex Differences in Morphology, Proliferation, Mechanosensitivity, and Cell-Matrix Remodeling

Marvin, J. C.; Brakewood, M. E.; Poon, M. L. S.; Andarawis-Puri, N.

10.1101/2022.09.13.507820 — bioengineering — Posted on 2022-09-16

2163 Sounding the alarm: sex differences in rat ultrasonic vocalizations during Pavlovian fear conditioning and extinction

Laine, M. A.; Mitchell, J. R.; Rhyner, J.; Clark, R.; Kannan, A.; Keith, J.; Pikus, M.; Bergeron, E.; Ravaglia, I.; Ulgenturk, E.; Shinde, A.; Shansky, R. M.

10.1101/2022.09.13.507801 — animal behavior and cognition — Posted on 2022-09-16

2164 A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

Chinnaiya, K.; Burbridge, S.; Jones, A.; Kim, D. W.; Place, E.; Manning, E.; Groves, I.; Sun, C.; Towers, M.; Blackshaw, S.; Placzek, M.

10.1101/2022.08.31.506043 — developmental biology — Posted on 2022-09-16

2165 Histopathological characteristics of different parts of surgical specimens of UPJ stenosis

Tuerdi, N.; Bai, J.; Liu, K.; Liu, S.; Xiong, H.; Gao, Y.; Li, J.

10.1101/2022.09.13.507884 — developmental biology — Posted on 2022-09-16

2166 Experimental and theoretical aspects of Golden Gate Assembly assays

Strzelecki, P.; Shpiruk, A.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Hebraud, P.; Beyer, N.; Busi, F.; Grange, W.

10.1101/2022.09.09.507109 — molecular biology — Posted on 2022-09-16

2167 Redox-based sensing controls bacterial chemotaxis to copper

Louis, G.; Cherry, P.; Michaux, C.; Rahuel-Clermont, S.; Dieu, M.; Tilquin, F.; Maertens, L.; Van Houdt, R.; Renard, P.; Perpete, E.; Matroule, J.-Y.

10.1101/2022.06.29.497744 — microbiology — Posted on 2022-09-16

2168 A Practical Alzheimer Disease Classifier via Brain Imaging-Based Deep Learning on 85,721 Samples

Lu, B.; Li, H.-X.; Chang, Z.-K.; Li, L.; Chen, N.-X.; Zhu, Z.-C.; Zhou, H.-X.; Li, X.-Y.; Wang, Y.-W.; Cui, S.-X.; Deng, Z.-Y.; Fan, Z.; Yang, H.; Chen, X.; Thompson, P. M.; Castellanos, F. X.; Yan, C.-G.

10.1101/2020.08.18.256594 — neuroscience — Posted on 2022-09-16

2169 Calibration of a Voronoi cell-based model for tumour growth using approximate Bayesian computation

Wang, X.; Jenner, A. L.; Salomone, R.; Drovandi, C.

10.1101/2022.09.13.507714 — systems biology — Posted on 2022-09-16

2170 The transcriptional and epigenetic reprogramming mediated by chronic IL1β exposure drives self-renewal ability and myeloid priming in TET2 deficient stem and progenitor cells.

McClatchy, J.; Strogantsev, R.; Wolfe, E.; Estabrook, J.; Lin, H.-Y.; Mohammadhosseini, M.; Davis, B.; Eden, C.; Goldman, D.; Fleming, W.; Cimmino, L.; Mohammed, H.; Agarwal, A.

10.1101/2022.09.15.507688 — cancer biology — Posted on 2022-09-16

2171 Elasticity generates indissoluble biomolecular condensates

Meng, L.; Lin, J.

10.1101/2022.02.09.479808 — biophysics — Posted on 2022-09-16

2172 FISHFactor: A Probabilistic Factor Model for Spatial Transcriptomics Data with Subcellular Resolution

Walter, F. C.; Stegle, O.; Velten, B.

10.1101/2021.11.04.467354 — bioinformatics — Posted on 2022-09-16

2173 Developmental changes of opsin gene expression in ray-finned fishes (Actinopterygii)

Lupse, N.; Kłodawska, M.; Truhlárova, V.; Kosatko, P.; Kaspar, V.; Bitja Nyom, A. R.; Musilova, Z.

10.1101/2022.04.28.489877 — evolutionary biology — Posted on 2022-09-16

2174 O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Contribute to the Mutational Trajectory in Variants of Concern

Gonzalez-Rodriguez, E.; Zol-Hanlon, M.; Bineva-Todd, G.; Marchesi, A.; Skehel, M.; Mahoney, K.; Roustan, C.; Borg, A.; Di Vagno, L.; Kjaer, S.; Wrobel, A. G.; Benton, D. J.; Nawrath, P.; Flitsch, S. L.; Joshi, D.; Gonzalez-Ramirez, A. M.; Wilkinson, K. A.; Wilkinson, R. J.; Hurtado-Guerrero, R.; Malaker, S. A.; Schumann, B.

10.1101/2022.09.15.508093 — cell biology — Posted on 2022-09-16

2175 Acute resistance to BET inhibitors remodels compensatory transcriptional programs via p300 co-activation

Shah, V.; Giotopoulos, G.; Osaki, H.; Meyerhoefer, M.; Meduri, E.; Schubert, B.; Yun, H.; Horton, S. J.; Agrawal-Singh, S.; Haehnel, P. S.; Basheer, F.; Lugo, D.; Kuehn, M. W.; Guezguez, B.; Theobald, M.; Kindler, T.; Gallipoli, P.; Prinjha, R. K.; Huntly, B. J.; Sasca, D.

10.1101/2022.09.14.507850 — cancer biology — Posted on 2022-09-16

2176 Single cell spatial analysis identifies regulators of brain tumor initiating cells

Mirzaei, R.; D'Mello, C.; Liu, M.; Nikolic, A.; Kumar, M.; Visser, F.; Bose, P.; Gallo, M.; Yong, V. W.

10.1101/2022.09.13.507846 — cancer biology — Posted on 2022-09-16

2177 A network of Notch-dependent and -independent her genes controls neural stem and progenitor cells in the zebrafish thalamic proliferation zone

Sigloch, C. E.; Spitz, D.; Driever, W.

10.1101/2022.09.15.508073 — developmental biology — Posted on 2022-09-16

2178 Exocytotic dynamics of glucagon-like peptide-1 from enteroendocrine L cell line is regulated by actin polymerization

Harada, K.; Takashima, M.; Kitaguchi, T.; TSUBOI, T.

10.1101/2022.09.14.508035 — cell biology — Posted on 2022-09-16

2179 The patterned assembly and stepwise Vps4-mediated disassembly of composite ESCRT-III polymers drives archaeal cell division

Hurtig, F.; Burgers, T. C. Q.; Cezanne, A.; Jiang, X.; Mol, F. N.; Traparic, J.; Tarrason Risa, G.; Arashiro Pulschen, A.; Harker-Kirschneck, L.; Saric, A.; Vlijm, R.; Baum, B.

10.1101/2022.09.16.508273 — cell biology — Posted on 2022-09-16

2180 Transcription factor FOXM1 specifies the loading of chromatin DNA to extracellular vesicles

Zhang, Y.; Ding, N.; Li, Y.; Zhao, X.; Yang, S.; Fu, P.; Peng, Y.; Cheng, H.; Ouyang, M.; Wang, R.; Wang, Y.; Liu, H.; Chen, Y.; Huang, X.; Yu, L.; Tan, Y.

10.1101/2022.01.27.477315 — cell biology — Posted on 2022-09-16

2181 Differences in sustained attention but not distraction in preschoolers from lower socioeconomic status backgrounds.

Hoyer, R. S.; Pakulak, E.; Bidet-Caulet, A.; Karns, C. M.

10.1101/2021.04.06.438161 — neuroscience — Posted on 2022-09-16

2182 Removal of extracellular human amyloid beta aggregates by extracellular proteases in C. elegans

Jongsma, E.; Mateos, J. M.; Ewald, C. Y.

10.1101/2022.09.14.507993 — cell biology — Posted on 2022-09-16

2183 Dynamics of annatto pigment synthesis and accumulation revealed by integrated chemical, anatomical, and RNA-Seq analyses

Moreira, V. S.; de Souza, V. C.; Soares, V. L. F.; Sousa, A. O.; de Nascimento, K. T. d. S.; de Santana, M. R.; Reboucas, T. N. H.; Leitao, C. A. E.; Goliatt, P. V. Z. C.; Faria, D. V.; Otoni, W. C.; Costa, M. G. C.

10.1101/2022.09.14.507995 — plant biology — Posted on 2022-09-16

2184 Self-supervised deep learning for pan-cancer mutation prediction from histopathology

Saldanha, O. L.; Loeffler, C. M. L.; Niehues, J. M.; van Treeck, M.; Seraphin, T. P.; Hewitt, K. J.; Cifci, D.; Veldhuizen, G. P.; Ramesh, S.; Pearson, A. T.; Kather, J. N.

10.1101/2022.09.15.507455 — cancer biology — Posted on 2022-09-16

2185 Phosphorylation sites are evolutionary checkpoints against liquid-solid transition in protein condensates

Ranganathan, S.; Dasmeh, P.; Furniss, S.; Shakhnovich, E.

10.1101/2022.09.15.508150 — biophysics — Posted on 2022-09-16

2186 Sister chromatid cohesion establishment during DNA replication termination

Cameron, G.; Gruszka, D.; Xie, S.; Nasmyth, K. A.; Srinivasan, M.; Yardimci, H.

10.1101/2022.09.15.508094 — biophysics — Posted on 2022-09-16

2187 Cell strain energy costs of active control of contractility

Solowiej-Wedderburn, J.; Dunlop, C.

10.1101/2022.09.16.508225 — biophysics — Posted on 2022-09-16

2188 HOPE-SIM, a cryo-structured illumination fluorescence microscopy system for accurately targeted cryo-electron tomography

Li, S.; Jia, X.; Niu, T.; Zhang, X.; Qi, C.; Xu, W.; Deng, H.; Sun, F.; Ji, G.

10.1101/2022.09.16.508243 — biophysics — Posted on 2022-09-16

2189 Oct4 interacts with subnucleosomal particles generated by Brg1 at enhancers

Nocente, M. C.; Mesihovic, A.; Drouineau, E.; Albawardi, W.; Dulary, C.; Ribierre, F.; Picaud, H.; Alibert, O.; Aude, J.-C.; Gilbert, N.; Ochsenbein, F.; Chantalat, S.; Gerard, M.

10.1101/2022.09.15.507958 — genomics — Posted on 2022-09-16

2190 Accumulation of mitochondrial ROS drives reductive glutamine metabolism

Sheng, X.

10.1101/2022.09.15.508079 — cell biology — Posted on 2022-09-16

2191 Cryogenic electron tomography reveals novel structures in the apical complex of Plasmodium falciparum

Sun, S. Y.; Zarko, L.-a. S.; Pintilie, G. D.; Kim, C. Y.; Staggers, S. R.; Schmid, M. F.; Egan, E. S.; Chiu, W.; Boothroyd, J. C.

10.1101/2022.09.14.508031 — cell biology — Posted on 2022-09-16

2192 MTCH2 is a mitochondrial outer membrane protein insertase

Guna, A.; Stevens, T. A.; Inglis, A. J.; Replogle, J. M.; Esantsi, T. K.; Muthukumar, G.; Shaffer, K. C. L.; Wang, M. L.; Pogson, A. N.; Jones, J. J.; Lomenick, B.; Chou, T.-F.; Weissman, J. S.; Voorhees, R. M.

10.1101/2022.09.15.508165 — cell biology — Posted on 2022-09-16

2193 Ablation of ZC3H11A causes early embryonic lethality and dysregulation of metabolic processes

Younis, S.; Jouneau, A.; Larsson, M.; Oudin, J.-F.; Brochard, V.; Andersson, L.

10.1101/2022.09.14.508037 — cell biology — Posted on 2022-09-16

2194 Accessory-cell-free differentiation of hematopoietic stem and progenitor cells into mature red blood cells

Boccacci, Y.; Dumont, N.; Doyon, Y.; Laganiere, J.

10.1101/2022.09.14.507311 — cell biology — Posted on 2022-09-16

2195 The filipodia-like protrusions of adjacent somatic cells shape the developmental potential of mouse oocytes

Crozet, F.; Letort, G.; Da Silva, C.; Eichmuller, A.; Tortorelli, A. F.; Belle, M.; Dumont, J.; Piolot, T.; Dauphin, A.; Coulpier, F.; Chedotal, A.; Maitre, J.-L.; Verlhac, M.-H.; Clarke, H.; Terret, M.-E.

10.1101/2022.09.15.508092 — cell biology — Posted on 2022-09-16

2196 Cellular Heterogeneity of Pluripotent Stem Cell Derived Cardiomyocyte Grafts is Mechanistically Linked to Treatable Arrhythmias

Selvakumar, D.; Clayton, Z. E.; Prowse, A.; Dingwall, S.; George, J.; Shah, H.; Chen, S.; Hume, R. D.; Tjahjadi, L.; Igoor, S.; Skelton, R. J. P.; Hing, A.; Paterson, H.; Foster, S. L.; Pearson, L.; Wilkie, E.; Jeyaprakash, P.; Wu, Z.; McArthur, J. R.; Barry, T.; Lu, J.; Tran, V.; Bennett, R.; Kotake, Y.; Campbell, T.; Turnbull, S.; Nguyen, Q.; Ni, G.; Grieve, S. M.; Palpant, N. J.; Pathan, F.; Kizana, E.; Kumar, S.; Gray, P. P.; Chong, J. J. H.

10.1101/2022.09.15.500719 — cell biology — Posted on 2022-09-16

2197 Alpha-T-catenin is expressed in peripheral nerves as a constituent of Schwann cell adherens junctions

Weng, A.; Rabin, E. E.; Flozak, A. S.; Aillon, R. P.; Chiarella, S. E.; Gottardi, C. J.

10.1101/2022.09.15.508190 — cell biology — Posted on 2022-09-16

2198 Formation of pericentromeric heterochromatin via ZNF518 that links satellite DNA to heterochromatin

Ohta, S.; Ohzeki, J.-I.; Sato, N.; Noma, K.-I.; Masumoto, H.

10.1101/2022.09.15.508097 — cell biology — Posted on 2022-09-16

2199 PCNA recruits cohesin loader Scc2/NIPBL to ensure sister chromatid cohesion

Psakhye, I.; Kawasumi, R.; Abe, T.; Hirota, K.; Branzei, D.

10.1101/2022.09.16.508217 — cell biology — Posted on 2022-09-16

2200 Multicentre comparison of biological and functional properties of mesenchymal stromal cells from different sources cultivated using a harmonised manufacturing workflow

Calcat-i-Cervera, S.; Rendra, E.; Scaccia, E.; Amadeo, F.; Hanson, V.; Wilm, B.; Murray, P.; O'Brien, T.; Taylor, A.; Bieback, K.

10.1101/2022.09.14.507944 — cell biology — Posted on 2022-09-16

2201 Inverse correlation between stress response and virulence factor expression in FASII antibiotic-adapted Staphylococcus aureus and consequences for infection

Wongdontree, P.; Millan-Oropeza, A.; Upfold, J.; Lavergne, J.-P.; Halpern, D.; Gloux, K.; Page, A.; Kenanian, G.; Grangeasse, C.; Henry, C.; Anba-Mondoloni, J.; Gruss, A.

10.1101/2022.09.09.506511 — microbiology — Posted on 2022-09-16

2202 Perception as a hierarchical competition: a model that differentiates imagined, veridical, and hallucinated percepts

Sulfaro, A. A.; Robinson, A. K.; Carlson, T. A.

10.1101/2022.09.02.506121 — neuroscience — Posted on 2022-09-16

2203 Polymer physics of structural evolution in synthetic yeast chromosomes

Stracquadanio, G.; Yang, K.; Boeke, J. D.; Koszul, R.; Bader, J. S.

10.1101/2022.09.14.507906 — synthetic biology — Posted on 2022-09-16

2204 Diverse branching forms regulated by a core auxin transport mechanism in plants

Spencer, V.; Bentall, L.; Harrison, C. J.

10.1101/2022.09.15.508075 — plant biology — Posted on 2022-09-16

2205 Ultraviolet radiation and dehydration stress induce overlapping transcriptional and metabolic responses in Syntrichia mosses

Ekwealor, J. T. B.; Kosina, S. M.; Bowen, B.; Silva, A. T.; Northen, T.; Oliver, M.; Mishler, B. D.

10.1101/2022.09.14.508022 — plant biology — Posted on 2022-09-16

2206 Chromoplast plastoglobules recruit the carotenoid biosynthetic pathway and contribute to carotenoid accumulation during tomato fruit maturation

Zita, W.; Bressoud, S.; Glauser, G.; Kessler, F.; Shanmugabalaji, V.

10.1101/2022.09.14.507955 — plant biology — Posted on 2022-09-16

2207 Time to budbreak is not enough: cold hardiness evaluation is necessary in dormancy and spring phenology studies

North, M.; Kovaleski, A. P.

10.1101/2022.09.15.508138 — plant biology — Posted on 2022-09-16

2208 A highly contiguous genome assembly of red perilla (Perilla frutescens) domesticated in Japan

Tamura, K.; Sakamoto, M.; Tanizawa, Y.; Mochizuki, T.; Matsushita, S.; Kato, Y.; Ishikawa, T.; Okuhara, K.; Nakamura, Y.; Bono, H.

10.1101/2022.09.16.508052 — plant biology — Posted on 2022-09-16

2209 Misexpression of the Homologues of Bryophyte Gametophyte-to-Sporophyte Control Genes in Arabidopsis Results in Germline Reprogramming and Phenotypes that Mirror Apomictic Development

Bezodis, W.; Prescott, H.; Dickinson, H. G.

10.1101/2022.09.15.508103 — plant biology — Posted on 2022-09-16

2210 Impairment of sugar transport in the vascular system acts on nitrogen remobilisation and nitrogen use efficiency in Arabidopsis.

Hoffmann, B.; Aubry, E.; Marmagne, A.; Dinant, S.; Chardon, F.; Le Hir, R.

10.1101/2022.09.14.507887 — plant biology — Posted on 2022-09-16

2211 Bridging the gap between in vitro and in silico single-molecule force spectroscopy

Gomes, D. E. B.; Melo, M. C. R.; Gomes, P. S. F. C.; Bernardi, R. C.

10.1101/2022.07.14.500151 — biophysics — Posted on 2022-09-16

2212 Investigating manta ray collective movements via drone surveys

Perryman, R. J. Y.; Brown, C.; Pasian, N.; Ward, A. J. W.; Kent, M. I. A.

10.1101/2022.07.29.501955 — animal behavior and cognition — Posted on 2022-09-16

2213 A self-adjusting, progressive shock strength procedure to investigate resistance to punishment: characterization in male and female rats

Desmercieres, S.; Lardeux, V.; Longueville, J.-E.; Hanna, M.; Panlilio, L. V.; Thiriet, N.; Solinas, M.

10.1101/2022.03.12.481595 — animal behavior and cognition — Posted on 2022-09-16

2214 The genome sequence of the Lumpy Skin Disease virus from the outbreak in India suggests a distinct lineage of the virus

Bhatt, L.; Bhoyar, R. C.; Jolly, B.; Israni, R.; Vignesh, H.; Scaria, V.; Sivasubbu, S.

10.1101/2022.09.15.508131 — genomics — Posted on 2022-09-16

2215 Comprehensive re-analysis of hairpin RNAs in fungi reveals ancestral links

Johnson, N. R.; Larrondo, L. F.; Alvarez, J. M.; Vidal, E. A.

10.1101/2022.09.15.508153 — genomics — Posted on 2022-09-16

2216 Universal abundance fluctuations across microbial communities, tropical forests, and urban populations

George, A. B.; O'Dwyer, J. P.

10.1101/2022.09.14.508016 — ecology — Posted on 2022-09-16

2217 Droplet microfluidics forward for tracing target cells at single-cell transcriptome resolution

Liu, Y.; Wang, S.; Lyu, M.; Xie, R.; Guo, W.; He, Y.; Shi, X.; Wang, Y.; Qi, J.; Zhu, Q.; Zhang, H.; Luo, T.; Chen, H.; Zhu, Y.; Dong, X.; Li, Z.; Gu, Y.; Mu, F.; Liu, L.; Xu, X.; Liu, Y.

10.1101/2022.09.13.507865 — cell biology — Posted on 2022-09-16

2218 Nuclear GAPDH in cortical microglia mediates stress-induced cognitive inflexibility

Ramos, A.; Ishizuka, K.; Namkung, H.; Hayes, L. N.; Saito, A.; Hayashida, A.; Srivastava, R.; Elkins, N.; Palen, T.; Carloni, E.; Tsujimura, T.; Calva, C.; Ikemoto, S.; Rais, R.; Slusher, B. S.; Niwa, M.; Saitoh, T.; Takimoto, E.; Sawa, A.

10.1101/2022.06.21.497065 — molecular biology — Posted on 2022-09-16

2219 SARS-CoV-2 infection of human neurons requires endosomal cell entry and can be blocked by inhibitors of host phosphoinositol-5 kinase

Kettunen, P. P.; Lesnikova, A.; Räsänen, N.; Ojha, R.; Palmunen, L.; Laakso, M.; Lehtonen, S.; Kuusisto, J.; Pietiläinen, O.; Vapalahti, O.; Koistinaho, J.; Rolova, T.; Balistreri, G.

10.1101/2022.09.14.508057 — neuroscience — Posted on 2022-09-16

2220 Systemic and intrinsic functions of ATRX in glial cell fate and CNS myelination

Rowland, M. E.; Jiang, Y.; Shafiq, S.; Ghahramani, A.; Pena-Ortiz, M. A.; Dumeaux, V.; Berube, N. G.

10.1101/2022.09.15.508143 — neuroscience — Posted on 2022-09-16

2221 HERBS: Histological E-data Registration in rodent Brain Spaces

Fuglstad, J. G.; Saldanha, P.; Paglia, J.; Whitlock, J. R.

10.1101/2021.10.01.462770 — neuroscience — Posted on 2022-09-16

2222 Meteorin alleviates Paclitaxel-induced peripheral neuropathy in mice

Sankaranarayanan, I.; Tavares-Ferreira, D.; He, L.; Kume, M.; Mwirigi, J. M.; Madsen, T. M.; Petersen, K. A.; Munro, G.; Price, T. J.

10.1101/2022.09.13.507857 — neuroscience — Posted on 2022-09-16

2223 3D electron diffraction reveals the chiral nature of the malaria pigment crystal hemozoin

Klar, P. B.; Waterman, D.; Gruene, T.; Mullick, D.; Song, Y.; Gilchrist, J. B.; Wen, W.; Biran, I.; Houben, L.; Regev-Rudzki, N.; Dzikowski, R.; Palatinus, L.; Zhang, P.; Leiserowitz, L.; Elbaum, M.

10.1101/2022.09.15.507960 — microbiology — Posted on 2022-09-16

2224 BRAin-wide Neuron quantification Tool reveals strong sexual dimorphism in the evolution of fear memory

Franceschini, A.; Mazzamuto, G.; Checcucci, C.; Chicci, L.; Fanelli, D.; Pavone, F. S.; Silvestri, L.

10.1101/2022.09.12.507637 — neuroscience — Posted on 2022-09-16

2225 APP family member dimeric complexes are formed predominantly in synaptic compartments

Schilling, S.; August, A.; Meleux, M.; Conradt, C.; Tremmel, L.; Teigler, S.; Koo, E. H.; Kins, S.; Eggert, S.

10.1101/2022.09.13.507759 — neuroscience — Posted on 2022-09-16

2226 Involvement of an IgE/Mast cell/B cell amplification loop in abdominal aortic aneurysm progression

Loste, A.; Clement, M.; Delbosc, S.; Guedj, K.; Senemaud, J.; Gaston, A.-T.; Morvan, M.; Even, G.; Gautier, G.; Eggel, A.; Arock, M.; Procopio, E.; Deschildre, C.; Louedec, L.; Michel, J.-B.; Deschamps, L.; Castier, Y.; Coscas, R.; Alsac, J.-M.; Launay, P.; Caligiuri, G.; Nicoletti, A.; Le Borgne, M.

10.1101/2022.09.13.507783 — pathology — Posted on 2022-09-16

2227 A new technology for isolating organellar membranes provides fingerprints of lipid bilayer stress

Reinhard, J.; Starke, L.; Klose, C.; Haberkant, P.; Hammaren, H.; Stein, F.; Klein, O.; Berhorst, C.; Stumpf, H.; Saenz, J. P.; Hub, J.; Schuldiner, M.; Ernst, R.

10.1101/2022.09.15.508072 — cell biology — Posted on 2022-09-16

2228 A novel gyrovirus associated with a fatal respiratory disease in yellow-eyed penguin (Megadyptes antipodes) chicks

Wierenga, J. R.; Morgan, K. J.; Hunter, S.; Taylor, H. S.; Argilla, L. S.; Webster, T.; Dubrulle, J.; Jorge, F.; Bostina, M.; Burga, L.; Holmes, E. C.; McInnes, K.; Geoghegan, J. L.

10.1101/2022.09.15.508173 — microbiology — Posted on 2022-09-16

2229 In vivo chromatic and spatial tuning of foveolar retinal ganglion cells in Macaca fascicularis

Godat, T.; Cottaris, N. P.; Patterson, S.; Kohout, K.; Parkins, K.; Yang, Q.; Strazzeri, J. M.; McGregor, J. E.; Brainard, D. H.; Merigan, W. H.; Williams, D. R.

10.1101/2022.02.28.482294 — neuroscience — Posted on 2022-09-16

2230 Transcription-induced active forces suppress chromatin motion by inducing a transient disorder-to-order transition

Shin, S.; Cho, H. W.; Shi, G.; Thirumalai, D.

10.1101/2022.04.30.490180 — biophysics — Posted on 2022-09-16

2231 Rookognise: Acoustic detection and identification of individual rooks in field recordings using multi-task neural networks

Martin, K.; Adam, O.; Obin, N.; Dufour, V.

10.1101/2022.02.19.481011 — bioinformatics — Posted on 2022-09-16

2232 HiC4D: Forecasting spatiotemporal Hi-C data with residual ConvLSTM

Liu, T.; Wang, Z.

10.1101/2022.09.10.507434 — bioinformatics — Posted on 2022-09-16

2233 A high-throughput strategy for enhancing aptamer performance across different environmental conditions

Wan, L. T.; Yoshikawa, A. M.; Eisenstein, M.; Soh, H. T.

10.1101/2022.09.13.507853 — bioengineering — Posted on 2022-09-16

2234 Association of Whole-Person Eigen-Polygenic Risk Scores with Alzheimer's Disease

Kharaghani, A.; Tio, E.; Milic, M.; Bennett, D. A.; De Jager, P. L.; Schneider, J. A.; Sun, L.; Felsky, D.

10.1101/2022.09.13.507735 — genetics — Posted on 2022-09-16

2235 European scenarios for future biological invasions

Perez-Granados, C.; Lenzner, B.; Golivets, M.; Saul, W.-C.; Jeschke, J. M.; Essl, F.; Peterson, G. D.; Rutting, L.; Latombe, G.; Adriaens, T.; Aldridge, D. C.; Bacher, S.; Bernardo-Madrid, R.; Brotons, L.; Diaz, F.; Gallardo, B.; Genovesi, P.; Gonzalez-Moreno, P.; Kuhn, I.; Kutlesa, P.; Leung, B.; Liu, C.; Pagitz, K.; Pastor, T.; Pauchard, A.; Rabitsch, W.; Roy, H. E.; Robertson, P.; Seebens, H.; Solarz, W.; Starfinger, U.; Tanner, R.; Vila, M.; Roura-Pascual, N.

10.1101/2022.09.13.507777 — ecology — Posted on 2022-09-16

2236 The trophic pyramid revisited: most animal classes have more predator than herbivore species

Klein, T.; Livne-Luzon, S.; Moran, U.

10.1101/2022.09.14.507913 — ecology — Posted on 2022-09-16

2237 Biphasic release propensity of mucin granules is supervised by TSPAN8

Wojnacki, J.; Lujan, A.; Foresti, O.; Aranda, C.; Bigliani, G.; Pena Rodriguez, M.; Brouwers, N.; Malhotra, V.

10.1101/2022.09.14.507971 — cell biology — Posted on 2022-09-16

2238 Intrinsic and extrinsic inhibition of cortical flow underlies symmetry breaking during unilateral cytokinesis

Hsu, C. R.; Sangha, G.; Fan, W.; Zheng, J.; Sugioka, K.

10.1101/2022.09.09.506560 — cell biology — Posted on 2022-09-16

2239 The mushroom body output encodes behavioral decision during sensory-motor transformation

Arican, C.; Schmitt, F. J.; Roessler, W.; Strube-Bloss, M. F.; Nawrot, M. P.

10.1101/2022.09.14.507924 — neuroscience — Posted on 2022-09-16

2240 Feature-space selection with banded ridge regression

Dupre la Tour, T.; Eickenberg, M.; Nunez-Elizalde, A. O.; Gallant, J. L.

10.1101/2022.05.05.490831 — neuroscience — Posted on 2022-09-16

2241 Intrinsically disordered proteins SAID1/2 condensate on SERRATE/ARS2 for dual inhibition of miRNA biogenesis in Arabidopsis

Shang, B.; Wang, L.; Yan, X.; Li, Y.; Li, C.; Wu, C.; Wang, T.; Guo, X.; Choi, S.; Zhang, T.; Wang, Z.; Tong, C.-Y.; Oh, T.; Zhang, X.; Wang, Z.; Peng, X.; Zhang, X.

10.1101/2022.09.13.507836 — plant biology — Posted on 2022-09-16

2242 Three-dimensional motions of GroEL during substrate protein recognition

Stapleton, K.; Mizobata, T.; Miyazaki, N.; Takatsuji, T.; Kato, T.; Iwasaki, K.; Standley, D. M.; Kawamura, T.; Nakane, T.; Takagi, J.; Mizohata, E.

10.1101/2022.09.15.508192 — biophysics — Posted on 2022-09-16

2243 Social dominance status and social stability in spiny mice (Acomys cahirinus) and its relation to ear-hole regeneration and glucocorticoids

Varholick, J. A.; Godinez, G.; Mobin, S.; Jenkins, A.; Romeo, R. D.; Barbazuk, W. B.; Maden, M.

10.1101/2022.09.13.507818 — animal behavior and cognition — Posted on 2022-09-16

2244 Single-cell brain organoid screening identifies developmental defects in autism

Li, C.; Fleck, J. S.; Martins-Costa, C.; Burkard, T. R.; Stuempflen, M.; Vertesy, A.; Peer, A. M.; Esk, C.; Elling, U.; Kasprian, G.; Corsini, N. S.; Treutlein, B.; Knoblich, J. A.

10.1101/2022.09.15.508118 — developmental biology — Posted on 2022-09-15

2245 A network of Notch-dependent and -independent her genes controls neural stem and progenitor cells in the zebrafish thalamic proliferation zone

Sigloch, C. E.; Spitz, D.; Driever, W.

10.1101/2022.09.15.508073 — developmental biology — Posted on 2022-09-15

2246 Complete blood count and selected serum parameters of Venus transgenic rabbits

Biro, B.; Skoda, G.; Hoffmann, O. I.; Hiripi, L.; Gocza, E.; Liptak, N.

10.1101/2022.09.14.507894 — molecular biology — Posted on 2022-09-15

2247 A toxin-antitoxin system ensures plasmid stability in Coxiella burnetii

Wachter, S.; Cockrell, D. C.; Miller, H. E.; Virtaneva, K.; Kanakabandik, K.; Darwitz, B.; Heinzen, R. A.; Beare, P. A.

10.1101/2022.09.15.508156 — microbiology — Posted on 2022-09-15

2248 Genomic variation during culture-adaptation of genetically complex Plasmodium falciparum clinical isolates

Claessens, A.; Stewart, L. B.; Drury, E.; Ahouidi, A. D.; Amambua-Ngwa, A.; Diakite, M.; Kwiatkowski, D. P.; Awandare, G. A.; Conway, D. J.

10.1101/2022.09.14.507918 — microbiology — Posted on 2022-09-15

2249 Mevalonate metabolites contribute to granulocyte chemotaxis and mortality in murine endotoxemia

Hussain, J.; Ousley, C. G.; Krauklis, S. A.; Dray, E. L.; Drnevich, J.; Justyna, K.; Distefano, M. D.; McKim, D. B.

10.1101/2022.09.13.507840 — immunology — Posted on 2022-09-15

2250 Structural basis for breadth development in a HIV-1 neutralizing antibody

Henderson, R.; Zhou, Y.; Stalls, V.; Wiehe, K.; Saunders, K. O.; Wagh, K.; Anasti, K.; Barr, M.; Parks, R.; Alam, S. M.; Korber, B.; Haynes, B. F.; Bartesaghi, A.; Acharya, P.

10.1101/2022.09.14.507935 — immunology — Posted on 2022-09-15

2251 Restoring functional D2- to D1-neuron correspondence enables goal-directed action control in long-lived striatal circuits

Bertran-Gonzalez, J.; Dinale, C.; Matamales, M.

10.1101/2022.09.14.508004 — neuroscience — Posted on 2022-09-15

2252 Microglial colonisation of the developing brain is facilitated by clonal expansion of highly proliferative progenitors and follows an allometric scaling

Barry-Carroll, L.; Greulich, P.; Marshall, A. R.; Riecken, K.; Fehse, B.; Askew, K. E.; Li, K.; Garaschuk, O.; Menassa, D. A.; Gomez-Nicola, D.

10.1101/2022.09.15.507569 — neuroscience — Posted on 2022-09-15

2253 Single cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation.

Nishimura, K.; Yang, S.; Lee, K.; Asgrimsdottir, E. S.; Nikouei, K.; Paslawski, W.; Gnodde, S.; Lyu, G.; Hu, L.; Salto, C.; Svenningsson, P.; Hjerling-Leffler, J.; Linnarsson, S.; Arenas, E.

10.1101/2022.09.15.507987 — neuroscience — Posted on 2022-09-15

2254 Recombinant protein condensation inside E. coli enables the development of building blocks for bioinspired materials engineering - biomimetic spider silk protein as a case study

Gabryelczyk, B.; Sammalisto, F.-E.; Gandier, J.-A.; Feng, J.; Beaune, G.; Timonen, J. V. I.; Linder, M. B.

10.1101/2022.09.14.507915 — synthetic biology — Posted on 2022-09-15

2255 Mapping and modeling human colorectal carcinoma interactions with the tumor microenvironment

Li, N.; Zhu, Q.; Tian, Y.; Ahn, K. J.; Wang, X.; Cramer, Z.; Folkert, I. W.; Yu, P.; Jou, J.; Adams-Tzivelekidis, S.; Sehgal, P.; Mahmoud, N. N.; Aarons, C. B.; Roses, R. E.; Thomas-Tikhonenko, A.; Furth, E. E.; Stanger, B. Z.; Rustgi, A. K.; Haldar, M.; Katona, B. W.; Tan, K.; Lengner, C. J.

10.1101/2022.09.13.506996 — cancer biology — Posted on 2022-09-15

2256 Oct4 interacts with subnucleosomal particles generated by Brg1 at enhancers

Gerard, M.; Nocente, M. C.; Mesihovic, A.; Drouineau, E.; Picaud, H.; Aude, J.-C.; Ochsenbein, F.; Albawardi, W.; Gilbert, N.; Dulary, C.; Ribierre, F.; Alibert, O.; Chantalat, S.

10.1101/2022.09.15.507958 — genomics — Posted on 2022-09-15

2257 Survey of activation-induced genome architecture reveals a novel enhancer of Myc

Chan, W. F.; Coughlan, H. D.; Ruhle, M.; Iannarella, N.; Alvarado, C.; Groom, J. R.; Keenan, C. R.; Kueh, A. J.; Wheatley, A. K.; Smyth, G.; Allan, R. S.; Johanson, T. M.

10.1101/2022.09.14.508046 — genetics — Posted on 2022-09-15

2258 Evolutionary crowdsourcing: alignment of fitness landscapes allows cross-species adaptation of a horizontally transferred gene

Kosterlitz, O.; Grassi, N.; Werner, B.; McGee, R. S.; Top, E. M.; Kerr, B.

10.1101/2022.09.13.507827 — evolutionary biology — Posted on 2022-09-15

2259 Siderophore-mediated iron partition promotes dynamical coexistence between cooperators and cheaters

Shao, J.; Rong, N.; Wu, Z.; Liu, B.; Shen, N.; Li, Z.

10.1101/2022.09.13.507871 — ecology — Posted on 2022-09-15

2260 TDP-43 safeguards the embryo genome from L1 retrotransposition

Li, T. D.; Murano, K.; Kitano, T.; Guo, Y.; Negishi, L.; Siomi, H.

10.1101/2022.09.13.507696 — developmental biology — Posted on 2022-09-15

2261 Heat induces multi-omic and phenotypic stress propagation in zebrafish embryos

Feugere, L.; Bates, A.; Emagbetere, T.; Chapman, E.; Malcolm, L.; Bulmer, K.; Hardege, J.; Beltran-Alvarez, P.; Valero, K. C. W.

10.1101/2022.09.15.508176 — molecular biology — Posted on 2022-09-15

2262 Assessment of Variability in the Plasma 7k SomaScan Proteomics Assay

Candia, J.; Daya, G. N.; Tanaka, T.; Ferrucci, L.; Walker, K. A.

10.1101/2022.09.14.507978 — molecular biology — Posted on 2022-09-15

2263 Arabidopsis DXO1 affects the processing of precursors of cytoplasmic and chloroplast ribosomal RNA.

Zakrzewska-Placzek, M.; Kwasnik, A.; Krzyszton, M.; Golisz-Mocydlarz, A.; Kufel, J.

10.1101/2022.09.14.507922 — molecular biology — Posted on 2022-09-15

2264 Emergence of plasmid-mediated RND-type efflux pump gene cluster tmexCD-toprJ in Shewanella xiamenensis in a water environment

Dao, T. D.; Takemura, T.; Kasuga, I.; Hirabayashi, A.; Nga, N. T.; Anh, P. H. Q.; Tu, N. D.; Trang, L. T.; Tran, H. H.; Shibayama, K.; Hasebe, F.; Suzuki, M.

10.1101/2022.09.15.508154 — microbiology — Posted on 2022-09-15

2265 Platelet phosphatidylserine is the critical mediator of thrombosis in heparin-induced thrombocytopenia

Zlamal, J.; Singh, A.; Weich, K.; Jaffal, H.; Uzun, G.; Althaus, K.; Bakchoul, T.

10.1101/2022.09.13.507721 — immunology — Posted on 2022-09-15

2266 Infant antibody repertoires during the first two years of influenza vaccination

Kuraoka, M.; Curtis, N. C.; Watanabe, A.; Tanno, H.; Shin, S.; Ye, K.; Macdonald, E.; Lavidor, O.; Kong, S.; Von Holle, T.; Windsor, I. W.; Ippolito, G. C.; Georgiou, G.; Walter, E. B.; Kelsoe, G. H.; Harrison, S. C.; Moody, M. A.; Bajic, G.; Lee, J.

10.1101/2022.09.13.507806 — immunology — Posted on 2022-09-15

2267 Single-nuclei transcriptomics of mammalian prion diseases identifies dynamic gene signatures shared between species

Dimitriadis, A.; Zhang, F.; Murphy, T.; Trainer, T.; Jaunmuktane, Z.; Schmidt, C.; Nazari, T.; Linehan, J.; Brandner, S.; Collinge, J.; Mead, S.; Vire, E.

10.1101/2022.09.13.507650 — neuroscience — Posted on 2022-09-15

2268 The structure, catalytic mechanism, and inhibitor identification of phosphatidylinositol remodeling MBOAT7

Wang, K.; Lee, C.-W.; Sui, X.; Kim, S.; Wang, S.; Higgs, A. B.; Baublis, A. J.; Voth, G. A.; Liao, M.; Walther, T. C.; Farese, R. V.

10.1101/2022.09.15.508141 — biochemistry — Posted on 2022-09-15

2269 Widely Distributed Biosynthetic Cassette Is Responsible for Diverse Plant Side-Chain-Cross-Linked Cyclopeptides

Lima, S. T.; Ampolini, B. G.; Underwood, E. B.; Graf, T. N.; Earp, C. E.; Khedi, I. C.; Chekan, J. R.

10.1101/2022.09.15.507631 — biochemistry — Posted on 2022-09-15

2270 Diversification of the Ruminant Skull Along an Evolutionary Line of Least Resistance

Rhoda, D.; Haber, A.; Angielczyk, K. D.

10.1101/2022.09.13.507810 — evolutionary biology — Posted on 2022-09-15

2271 Developmental rate displays effects of inheritance but not of sex in inter-population hybrids of Tigriopus californicus

Healy, T. M.; Hargadon, A. C.; Burton, R. S.

10.1101/2022.09.13.507602 — evolutionary biology — Posted on 2022-09-15

2272 Urbanisation impacts plumage colouration in a songbird across Europe: evidence from a correlational, experimental, and meta-analytical approach

Salmon, P.; Lopez-Idiaquez, D.; Capilla-Lasheras, P.; Perez-Tris, J.; Isaksson, C.; Watson, H.

10.1101/2022.09.13.507844 — evolutionary biology — Posted on 2022-09-15

2273 Colistin resistance mutations in phoQ sensitize Klebsiella pneumoniae to IgM-mediated complement killing

van der Lans, S. P. A.; Janet-Maitre, M.; Masson, F. M.; Walker, K. A.; Doorduijn, D. J.; Janssen, A. B.; van Schaik, W.; Attree, I.; Rooijakkers, S. H. M.; Bardoel, B. W.

10.1101/2022.09.15.508115 — microbiology — Posted on 2022-09-15

2274 DEGoldS: a workflow to assess the accuracy of differential expression analysis pipelines through gold-standard construction

Hurtado, M.; Mora-Marquez, F.; Soto, A.; Marino, D.; Goicoechea, P. G.; Lopez de Heredia, U.

10.1101/2022.09.13.507753 — bioinformatics — Posted on 2022-09-15

2275 SynBOLD-DisCo: Synthetic BOLD images for distortion correction of fMRI without additional calibration scans

Yu, T.; Cai, L. Y.; Morgan, V. L.; Goodale, S. E.; Englot, D. J.; Chang, C. E.; Landman, B. A.; Schilling, K. G.

10.1101/2022.09.13.507794 — bioengineering — Posted on 2022-09-15

2276 Allelic and Gene Dosage Effects Involving Uromodulin Aggregates Drive Autosomal Dominant Tubulointerstitial Kidney Disease

Schiano, G.; Lake, J.; Mariniello, M.; Schaeffer, C.; Harvent, M.; Rampoldi, L.; Olinger, E. G.; Devuyst, O.

10.1101/2022.09.13.507770 — genetics — Posted on 2022-09-15

2277 A high throughput method for egg size measurement in Drosophila

barghi, n.; Ramirez-Lanzas, C.

10.1101/2022.09.13.507758 — evolutionary biology — Posted on 2022-09-15

2278 Behind the scene of body mass allometries

Witting, L.

10.1101/2022.09.13.507740 — evolutionary biology — Posted on 2022-09-15

2279 Phenotypic switch and reduced the growth of melanoma spheroids in the presence of mast cell-conditioned medium: potential impact of nutrient starvation effects

Grujic, M.; Nguyen, T.; Hechard, T.; Wang, H.; Lampinen, M.; Paivandy, A.; Pejler, G.

10.1101/2022.09.13.507791 — immunology — Posted on 2022-09-15

2280 Major Histocompatibility Complex class I heavy chains localize in both cytoplasmic and nuclear compartment

Gomez-Herranz, M.; Dziadosz, A.; Mikac, S.; Rychlowski, M.; Fahraeus, R.; Marek-Trzonkowska, N.; Chrusciel, E.; Urban-Wojciuk, Z.; Papak, I.; Arcimowicz, L.; Marjanski, T.; Rzyman, W.; Sznarkowska, A.

10.1101/2022.09.13.507738 — immunology — Posted on 2022-09-15

2281 CXCR4 controls movement and degranulation of CD8+ T cells in the influenza-infected lung via differential effects on interaction and tissue scanning

Mrass, P.; Kinjo, I.; Byrum, J. R.; Torres, D. J.; Baker, S. F.; Cannon, J. L.

10.1101/2022.09.13.507813 — immunology — Posted on 2022-09-15

2282 Simulating Short-Term Synaptic Plasticity on SpiNNaker Neuromorphic Hardware

Lankarany, M.; Azzalini, L. J.

10.1101/2022.09.13.507796 — neuroscience — Posted on 2022-09-15

2283 Viridiplantae-specific GLXI and GLXII isoforms co-evolved and detoxify glucosone in planta

Balparda, M.; Schmitz, J.; Duemmel, M.; Wuthenow, I. C.; Schmidt, M.; Alseekh, S.; Fernie, A. R.; Lercher, M. J.; Maurino, V. G.

10.1101/2022.09.13.507747 — plant biology — Posted on 2022-09-15

2284 Molecular landscape and functional characterization of centrosome amplification in ovarian cancer

Sauer, C. M.; Hall, J. A.; Couturier, D.-L.; Bradley, T.; Piskorz, A. M.; Griffiths, J.; Sawle, A.; Eldridge, M. D.; Smith, P.; Hosking, K.; Reinius, M. A.; Morrill Gavarro, L.; Mes-Masson, A.-M.; Ennis, D.; Millan, D.; Hoyle, A.; McNeish, I. A.; Jimenez-Linan, M.; Correia Martins, F.; Tischer, J.; Vias, M.; Brenton, J. D.

10.1101/2022.09.13.507750 — cancer biology — Posted on 2022-09-15

2285 A bioinformatics pipeline for the assessment of the evolutionary relationship of some Drosophila species based on class II transposons mapping

Constantin, N. D.; Bologa, A. M.; Ratiu, A. C.; Ecovoiu, A. A.

10.1101/2022.09.13.507812 — bioinformatics — Posted on 2022-09-15

2286 The Aphelenchoides genomes reveal major events of horizontal gene transfers in clade IV nematodes

Lai, C.-K.; Lee, Y.; Ke, H.-M.; Lu, M. R.; Liu, W.-A.; Lee, H.-H.; Liu, Y.-C.; Yoshiga, T.; Kikuchi, T.; Chen, P. J.; Tsai, I. J.

10.1101/2022.09.13.507733 — genomics — Posted on 2022-09-15

2287 Genomic erosion in the assessment of species extinction risk and recovery potential

van Oosterhout, C. v.; Speak, S. A.; Birley, T.; Bortoluzzi, C.; Percival-Alwyn, L.; Urban, L. H.; Groombridge, J. J.; Segelbacher, G.; Morales, H. E.

10.1101/2022.09.13.507768 — genomics — Posted on 2022-09-15

2288 Loss of H3.1K27me1 in Arabidopsis confers resistance to Geminivirus by sequestering DNA repair proteins onto rDNA and defense-related genes

Wang, Z.; Gonzalez, C. M. C.; Zhao, C.; Tong, C.-Y.; Li, C.; Liu, Z.; Xie, K.; Zhu, J.; Wu, Z.; Peng, X.; Jacob, Y.; Michaels, S. D.; Jacobsen, S. E.; Zhang, X.

10.1101/2022.09.13.507805 — genetics — Posted on 2022-09-15

2289 The evolution of dynamic and flexible courtship displays that reveal individual quality

Hollon, S. H.; Garcia Ruiz, I.; Veen, T.; Fawcett, T. W.

10.1101/2022.09.13.507802 — evolutionary biology — Posted on 2022-09-15

2290 Chilean bee diversity: Contrasting patterns of species and phylogenetic turnover along a large-scale ecological gradient

Marshall, L.; Ascher, J. S.; Villagra, C.; Beaugendre, A.; Herrera, V.; Henriquez-Piskulich, P.; Vera, A.; Vereecken, N. J.

10.1101/2022.09.13.506767 — ecology — Posted on 2022-09-15

2291 Single-cell transcriptomics reveal distinct subsets of activated dendritic cells in the tumor microenvironment

To, T. K. J.; Devalaraja, S.; Folkert, I. W.; Zhai, L.; Lobel, G. P.; Haldar, M.

10.1101/2022.09.13.507746 — immunology — Posted on 2022-09-15

2292 No need for extensive artifact rejection for ICA - A multi-study evaluation on stationary and mobile EEG datasets

Klug, M.; Berg, T.; Gramann, K.

10.1101/2022.09.13.507772 — neuroscience — Posted on 2022-09-15

2293 Multiomic Approach Characterises the Neuroprotective Role of Retromer in Regulating Lysosomal Health

Daly, J. L.; Danson, C. M.; Lewis, P. A.; Riccardo, S.; Di Filippo, L.; Cacchiarelli, D.; Cross, S. J.; Heesom, K. J.; Ballabio, A.; Edgar, J. R.; Cullen, P. J.

10.1101/2022.09.13.507260 — neuroscience — Posted on 2022-09-15

2294 A climate-driven compartmental model for fungal diseases in fruit orchards: The impacts of climate change on a brown rot-peach system

Bevacqua, D.; Vanalli, C.; Casagrandi, R.; Gatto, M.

10.1101/2022.09.13.507724 — plant biology — Posted on 2022-09-15

2295 Suggesting disease associations for overlooked metabolites using literature from metabolic neighbours

Delmas, M.; Filangi, O.; Duperier, C.; Paulhe, N.; Vinson, F.; Rodriguez-Mier, P.; Giacomoni, F.; Jourdan, F.; Frainay, C.

10.1101/2022.09.13.507596 — bioinformatics — Posted on 2022-09-15

2296 Socially transmitted innovations in dynamic predator-prey systems

Kikuchi, D. W.; Simon, M. W.

10.1101/2022.09.13.507786 — animal behavior and cognition — Posted on 2022-09-15

2297 Impact of female mate copying on male morph dynamics

Patil, S.; Noebel, S.; Gokhale, C. S.

10.1101/2022.09.13.507757 — animal behavior and cognition — Posted on 2022-09-15

2298 Association of Whole-Person Eigen-Polygenic Risk Scores with Alzheimer's Disease

Kharaghani, A.; Tio, E.; Milic, M.; Bennett, D. A.; De Jager, P. L.; Schneider, J. A.; Sun, L.; Felsky, D.

10.1101/2022.09.13.507735 — genetics — Posted on 2022-09-15

2299 The clustering of spatially associated species unravels patterns in Bornean tree species distributions

Pang, S. E. H.; Slik, F. J. W.; Zurell, D.; Webb, E. L.

10.1101/2022.09.13.507725 — ecology — Posted on 2022-09-15

2300 Convergent community assembly among globally separated acidic cave biofilms

Jones, D. S.; Schaperdoth, I.; Northup, D. E.; Gomez-Cruz, R.; Macalady, J. L.

10.1101/2022.09.13.507874 — microbiology — Posted on 2022-09-15

2301 Preparatory neural activity differs between Selective Attention and Perceptual Expectations

G. Penalver, J. M.; Lopez-Garcia, D.; Gonzalez-Garcia, C.; Aguado-Lopez, B.; Gorriz, J. M.; Ruz, M.

10.1101/2022.09.13.507583 — neuroscience — Posted on 2022-09-15

2302 Fast Adaptation to Rule Switching using Neuronal Surprise

Barry, m. L. L. R.; Gerstner, W.

10.1101/2022.09.13.507727 — neuroscience — Posted on 2022-09-15

2303 Calibration of a Voronoi cell-based model for tumour growth using approximate Bayesian computation

Wang, X.; Drovandi, C.; Jenner, A. L.; Salomone, R.

10.1101/2022.09.13.507714 — systems biology — Posted on 2022-09-15

2304 Reduced coenzyme Q synthesis confers non-target site resistance to the herbicide thaxtomin A

Casey, C.; Köcher, T.; Champion, C.; Jandrasits, K.; Mosiolek, M.; Bonnot, C.; Dolan, L.

10.1101/2022.09.13.507736 — plant biology — Posted on 2022-09-15

2305 Phenotypic profiling of macrocyclic lactones on parasitic Schistosoma flatworms

Ryan, K. T.; Wheeler, N. J.; Kamara, I. K.; Johnson, H.; Humphries, J. E.; Zamanian, M.; Chan, J. D.

10.1101/2022.09.12.507717 — pharmacology and toxicology — Posted on 2022-09-15

2306 Crowding induced morphological changes in synthetic lipid vesicles determined using smFRET

Quinn, S. D.; Dresser, L.; Graham, S.; Conteduca, D.; Shepherd, J.; Leake, M. C.

10.1101/2022.05.31.494132 — biophysics — Posted on 2022-09-15

2307 Genomic health is dependent on long-term population demographic history

Wootton, E.; Robert, C.; Taillon, J.; Shafer, A.; Cote, S.

10.1101/2022.08.16.503900 — genomics — Posted on 2022-09-15

2308 Spatially resolved transcriptomic profiling of degraded and challenging fresh frozen samples

Mirzazadeh, R.; Andrusivova, Z.; Larsson, L.; Newton, P.; Alonso Galicia, L.; Abalo, X. M.; Avijgan, M.; Kvastad, L.; Denadai-Souza, A.; Stakenborg, N.; Firsova, A. B.; Shamikh, A.; Jurek, A.; Schultz, N.; Nister, M.; Samakovlis, C.; Boeckxstaens, G.; Lundeberg, J.

10.1101/2022.09.13.507728 — genomics — Posted on 2022-09-15

2309 Immune Isoform Atlas: Landscape of alternative splicing in human immune cells

Inamo, J.; Suzuki, A.; Ueda, M.; Yamaguchi, K.; Nishida, H.; Suzuki, K.; Kaneko, Y.; Takeuchi, T.; Ishihama, Y.; Yamamoto, K.; Kochi, Y.

10.1101/2022.09.13.507708 — genetics — Posted on 2022-09-15

2310 O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Contribute to the Mutational Trajectory in Variants of Concern

10.1101/2022.09.15.508093 — cell biology — Posted on 2022-09-15

2311 Global characterization of gene expression in the brain of starved immature R. prolixus

Nevoa, J. C.; Estivalis, J. M. L.; Pais, F. S.-M.; Pinto Marliere, N.; Fernandes, G. R.; Lorenzo, M. G.; Guarneri, A. A.

10.1101/2022.09.01.506236 — molecular biology — Posted on 2022-09-15

2312 Bacterial Microbiome of Foreskin Tissue: Impact of Short-course PrEP and Host Inflammation

Maust, B. S.; Petkov, S.; Herrera, C.; Feng, C.; Brown, B. P.; Lebina, L.; Opoka, D.; Ssemata, A.; Pillay, N.; Serwanga, J.; Seatlholo, P.; Namubiru, P.; Odoch, G.; Mugaba, S.; Seiphetlo, T.; Gray, C. M.; Kaleebu, P.; Webb, E. L.; Martinson, N.; Chiodi, F.; Fox, J.; Jaspan, H. B.; the CHAPS team,

10.1101/2022.08.29.505718 — microbiology — Posted on 2022-09-15

2313 Novel Multi-Epitope Vaccine candidate derived from critically important proteins of Monkeypox isolates

Srivastava, S.; Kolbe, M.

10.1101/2022.09.15.507808 — immunology — Posted on 2022-09-15

2314 Dormancy of disseminated prostate cancer cells in the bone cortex is induced by osteoblasts

Liu, R.; Su, S.; Liu, K.; Xing, J.; Stangis, M.; Jacho, D. P.; Yildirim-Ayan, E. D.; Yu, H.; Chen, B.; Li, X.

10.1101/2022.09.02.506436 — cancer biology — Posted on 2022-09-15

2315 A hybrid structure determination approach to investigate the druggability of the nucleocapsid protein of SARS-CoV-2

Padroni, G.; Bikaki, M.; Novakovic, M.; Wolter, A. C.; Ruedisser, S. H.; Gossert, A. D.; Leitner, A.; Allain, F. H.- T.

10.1101/2022.09.15.507991 — biophysics — Posted on 2022-09-15

2316 Fast bioluminescent nucleic acid detection using one-pot isothermal amplification and dCas9-based split luciferase complementation

van der Veer, H. J.; van Aalen, E. A.; Michielsen, C. M. S.; Hanckmann, E. T. L.; Deckers, J.; van Borren, M. M. G. J.; Flipse, J.; Loonen, A. J. M.; Schoeber, J. P. H.; Merkx, M.

10.1101/2022.09.12.507659 — bioengineering — Posted on 2022-09-15

2317 MicroFPGA: an affordable FPGA platform for microscope control

Deschamps, J.; Kieser, C.; Hoess, P.; Deguchi, T.; Ries, J.

10.1101/2022.06.07.495178 — biophysics — Posted on 2022-09-15

2318 A photopolymerizable hydrogel enhances intramyocardial vascular cell delivery and promotes post-myocardial infarction healing by polarizing pro-regenerative neutrophils

Hong, X.; Luo, A. C.; Doulamis, I.; Oh, N.; Im, G.-B.; del Nido, P. J.; Martin, J. M. M.; Lin, R.-Z.

10.1101/2022.06.30.497378 — bioengineering — Posted on 2022-09-15

2319 Metabolic Signatures of Performance in Elite World Tour Professional Cyclists

Nemkov, T.; Cendali, F.; Stefanoni, D.; Martinez, J.; Hansen, K. C.; San-Millan, I.; D'Alessandro, A.

10.1101/2022.09.13.507793 — biochemistry — Posted on 2022-09-15

2320 Mutagenesis Induced by Protonation of Single-Stranded DNA is Linked to Glycolytic Sugar Metabolism

Gelova, S. P.; Chan, K.

10.1101/2022.07.14.500049 — genetics — Posted on 2022-09-15

2321 4EBP1/2 support tumorigenicity and cell survival during energetic stress by translationally regulating fatty acid synthesis

Levy, T.; Voeltzke, K.; Hauffe, L.; Alasad, K.; Snaebjornsson, M.; Marciano, R.; Scharov, K.; Planque, M.; Vriens, K.; Christen, S.; Funk, C. M.; Hassiepen, C.; Kahler, A.; Heider, B.; Picard, D.; Lim, J. K.; Bas, Z.; Bendrin, K.; Vargas-Toscano, A.; Kahlert, U.; Remke, M.; Elkabets, M.; Grunewald, T. G.; Reichert, A. S.; Fendt, S.-M.; Schulze, A.; Reifenberger, G.; Rotblat, B.; Leprivier, G.

10.1101/2022.09.09.507243 — cell biology — Posted on 2022-09-15

2322 Identification of genes required for long term survival of L. pneumophila in water.

Aurass, P.; Kim, S.; Pinedo, V.; Cava, F.; Isberg, R. R.

10.1101/2022.09.14.508055 — microbiology — Posted on 2022-09-15

2323 Mycobacterium tuberculosis DprE1 inhibitor OPC-167832 is active against Mycobacterium abscessus in vitro

Sarathy, J. P.; Zimmerman, M.; Gengenbacher, M.; Dartois, V. A.; Dick, T.

10.1101/2022.09.14.508059 — microbiology — Posted on 2022-09-15

2324 Protein arginine phosphorylation and de-phosphorylation facilitate protein homeostasis by an AAA+ chaperone protease system

Alver, R.; Hantke, I.; Cornejo, F. A.; Gunka, K.; Rämisch, S.; Moliere, N.; Charpentier, E.; Turgay, K.

10.1101/2022.09.15.508104 — microbiology — Posted on 2022-09-15

2325 Drug resistance-associated mutations in Plasmodium UBP-1 disrupt ubiquitin hydrolysis

Smith, C.; Henrici, R.; Karpiyevich, M.; Ansbro, M. R.; Hoshizaki, J.; van der Heden van Noort, G. J.; Ascher, D. B.; Sutherland, C. J.; Lee, M. C. S.; Artavanis-Tsakonas, K.

10.1101/2022.09.15.508122 — microbiology — Posted on 2022-09-15

2326 IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

Nelson, C. E.; Foreman, T. W.; Kauffman, K. D.; Sakai, S.; Gould, S. T.; Fleegle, J. D.; Gomez, F.; NIAID/DIR Tuberculosis Imaging Program, ; Le Nouen, C.; Liu, X.; Burdette, T. L.; Garza, N. L.; Lafont, B. A. P.; Brooks, K.; Arlehamn, C. S. L.; Weiskopf, D.; Sette, A.; Hickman, H. D.; Buchholz, U. J.; Johnson, R. F.; Brenchley, J. M.; Via, L. E.; Barber, D. L.

10.1101/2022.09.13.507852 — immunology — Posted on 2022-09-15

2327 Style Transfer Generative Adversarial Networks to Harmonize Multi-Site MRI to a Single Reference Image to Avoid Over-Correction

Liu, M.; Zhu, A.; Maiti, P.; Thomopoulos, S. I.; Gadewar, S.; Chai, Y.; Kim, H.; Jahanshad, N.; Alzheimer's Disease Neuroimaging Initiative,

10.1101/2022.09.12.506445 — neuroscience — Posted on 2022-09-15

2328 Conduction Velocities of Excitatory Axons Innervating Parvalbumin Interneurons in Primary Somatosensory Cortex

Scheuer, K. S.; Zhao, X.; Jackson, M. B.

10.1101/2022.07.27.501767 — neuroscience — Posted on 2022-09-15

2329 PhysiPKPD: A pharmacokinetics and pharmacodynamics module for PhysiCell

Bergman, D. R.; Marazzi, L.; Chowkwale, M.; Maheshvare M, D.; Bidanta, S.; Mapder, T.; Li, J.

10.1101/2022.09.12.507681 — systems biology — Posted on 2022-09-15

2330 OPA1 Downregulation in Skeletal Muscle Induces MERC formation in an ATF4-Dependent Manner

10.1101/2022.09.12.507669 — biophysics — Posted on 2022-09-15

2331 Derepression masquerades as activation in a pentameric ligand-gated ion channel

Tessier, C. J. G.; Emlaw, J. R.; Sturgeon, R. M.; daCosta, C. J. B.

10.1101/2022.09.13.507804 — biophysics — Posted on 2022-09-15

2332 Benchmarking thiolate driven photoswitching of cyanine dyes

Herdly, L.; Tinning, P. W.; Geiser, A.; Taylor, H.; Gould, G. W.; van de Linde, S.

10.1101/2022.09.15.507984 — biophysics — Posted on 2022-09-15

2333 Probing mechanical interaction of immune receptors and cytoskeleton by membrane nanotube extraction

Manca, F.; Eich, G.; N'Dao, O.; Normand, L.; Sengupta, K.; Limozin, L.; Puech, P.-H.

10.1101/2022.09.15.508080 — biophysics — Posted on 2022-09-15

2334 Submicron-sized in-situ osmotic pressure sensors for in-vitro applications in biology

Zhang, W.; Bertinetti, L.; Yavuzsoy, E. C.; Gao, C.; Schneck, E.; Fratzl, P.

10.1101/2022.09.13.507780 — biophysics — Posted on 2022-09-15

2335 Effect of Methamphetamine on Ultraweak Photon Emission and Level of Reactive Oxygen Species in Male Rat Brain

Lotfealian, A.; Esmaeilpour, T.; Anvari, M.; Namavar, M.; Karbalaei, N.; Shahedi, A.; Bokkon, I.; Zadeh-Haghigh, H.; Simon, C.; Salari, V.; Oblak, D.

10.1101/2022.09.14.508017 — biophysics — Posted on 2022-09-15

2336 Metabolons, quinary structure, and domain motion: enzyme choreography in the cytoplasm

Samuel, P. P.; Rickard, M. M.; Pogorelov, T. V. V.; Gruebele, M.

10.1101/2022.09.13.507800 — biophysics — Posted on 2022-09-15

2337 Sorting of droplets at kHz rates using absorbance activated acoustic sorting

Richter, E. S.; Link, A.; McGrath, J. S.; Sparrow, R. W.; Gantz, M.; Medcalf, E. J.; Hollfelder, F.; Franke, T.

10.1101/2022.09.13.507732 — biophysics — Posted on 2022-09-15

2338 On the Aging and Reproductive Consequences of Biological Complexity

Sarkar, T. J.

10.1101/2022.09.14.505979 — biophysics — Posted on 2022-09-15

2339 Direct digital sensing of protein biomarkers in solution

Krainer, G.; Saar, K. L.; Arter, W. E.; Welsh, T. J.; Czekalska, M. A.; Jacquat, R. P. B.; Peter, Q.; Traberg-Christensen, W.; Pujari, A.; Jayaram, A. K.; Challa, P.; Taylor, C. G.; van der Linden, L.-M.; Franzmann, T.; Owens, R. M.; Alberti, S.; Klenerman, D.; Knowles, T. P. J.

10.1101/2020.05.24.113498 — biophysics — Posted on 2022-09-15

2340 The performance of deep generative models for learning joint embeddings of single-cell multi-omics data

Brombacher, E.; Hackenberg, M.; Kreutz, C.; Binder, H.; Treppner, M.

10.1101/2022.06.06.494951 — bioinformatics — Posted on 2022-09-15

2341 The GR2D2 Estimator for the Precision Matrices

Gan, D.; Yin, G.; Zhang, Y.

10.1101/2022.03.22.485374 — bioinformatics — Posted on 2022-09-15

2342 Imbalanced classification for protein subcellularlocalisation with multilabel oversampling

Rana, P.; Sowmya, A.; Meijering, E.; Song, Y.

10.1101/2022.09.12.507675 — bioinformatics — Posted on 2022-09-15

2343 Decision Tree Ensembles Utilizing Multivariate Splits Are Effective at Investigating Beta-Diversity in Medically Relevant 16S Amplicon Sequencing Data

Rudar, J.; Golding, G. B.; Kremer, S. C.; Hajibabaei, M.

10.1101/2022.03.31.486647 — bioinformatics — Posted on 2022-09-15

2344 Toxicity of microplastics and plastic additive co-exposure in liver Disse organoids from healthy donors and patient-derived induced pluripotent stem cells

Liang, S.; Luo, Y.; Su, Y.; Feng, L.; Xu, M.; Yao, R.

10.1101/2022.09.12.506301 — bioengineering — Posted on 2022-09-15

2345 Phage-Assisted, Active Site-Directed Ligand Evolution of a Potent and Selective Histone Deacetylase 8 Inhibitor

Morse, J. S.; Sheng, Y. J.; Hampton, J. T.; Sylvain, L. D.; Das, S.; Alugubelli, Y. R.; Chen, P.-H. C.; Yang, K. S.; Xu, S.; Fierke, C. A.; Liu, W. R.

10.1101/2022.09.14.508049 — biochemistry — Posted on 2022-09-15

2346 AlphaFold2-based fusion design deciphers crucial role of the E3 UFL1 N-terminal helix in E2 UFC1 binding and ufmylation

Banerjee, S.; Varga, J. K.; Kumar, M.; Schueler-Furman, O.; Wiener, R.

10.1101/2022.09.15.508077 — biochemistry — Posted on 2022-09-15

2347 Simple, rapid, and sensitive quantification of dolichyl phosphates using phosphate methylation and reverse-phase liquid chromatography-high resolution mass spectrometry

Kale, D.; Kikul, F.; Phapale, P.; Beedgen, L.; Thiel, C.; Bruegger, B.

10.1101/2022.09.14.504994 — biochemistry — Posted on 2022-09-15

2348 Structural insights into the elevator-type transport mechanism of a bacterial ZIP metal transporter

Zhang, Y.; Jiang, Y.; Gao, K.; Sui, D.; Yu, P.; Su, M.; Wei, G.; Hu, J.

10.1101/2022.09.14.508043 — biochemistry — Posted on 2022-09-15

2349 The relationship between the interdisciplinary activation of children's scientific concepts and their mastery of basic knowledges: A pre-study based on reaction times

Wang, Z.

10.1101/2022.09.12.506518 — animal behavior and cognition — Posted on 2022-09-15

2350 Environment-wide and epigenome-wide association study of adiposity in "Children of 1997" birth cohort

Zhao, J.; Fan, B.; Huang, J.; Cowling, B. J.; Au Yeung, S. L. R.; Baccarelli, A.; M. Leung, G.; Schooling, C. M.

10.1101/2022.09.12.507623 — genetics — Posted on 2022-09-15

2351 Cysteine post-translational modifications regulate protein interactions of caveolin-3

Ashford, F.; Brown, E.; Calaghan, S.; Jayasinghe, I.; Henderson, C.; Fuller, W.; Wypijewski, K.

10.1101/2022.09.15.508083 — cell biology — Posted on 2022-09-15

2352 COP I and II dependent trafficking controls ER-associated degradation in mammalian cells

Ogen-Shtern, N.; Chang, C.; Saad, H.; Mazkereth, N.; Patel, C.; Shenkman, M.; Lederkremer, G. Z.

10.1101/2022.04.07.487480 — cell biology — Posted on 2022-09-15

2353 Gene amplifications cause high-level resistance against albicidin in Gram-negative bacteria

Saathoff, M.; Kosol, S.; Semmler, T.; Wolf, S. A.; Dimos, N.; Kupke, J.; Seidel, M.; Ghaziasaeedi, F.; Tedin, K.; Kuropka, B.; Czyszczon, W.; Ghilarov, D.; Graetz, S.; Heddle, J. G.; Loll, B.; Suessmuth, R. D.; Fulde, M.

10.1101/2022.09.15.507240 — microbiology — Posted on 2022-09-15

2354 Interdigitated immunoglobulin arrays form the hyperstable surface layer of the extremophilic bacterium Deinococcus radiodurans

von Kuegelgen, A.; van Dorst, S.; Yamashita, K.; Sexton, D. L.; Tocheva, E. I.; Murshudov, G. N.; Alva, V.; Bharat, T.

10.1101/2022.09.15.508085 — microbiology — Posted on 2022-09-15

2355 Recent O-antigen diversification masks highly pathogenic STEC O104:H4

Lang, C.; Fruth, A.; Campell, I. W.; Jenkins, C.; Smith, P.; Strockbine, N.; Weill, F.-X.; Nübel, U.; Grad, Y. H.; Waldor, M. K.; Flieger, A.

10.1101/2022.09.15.508078 — microbiology — Posted on 2022-09-15

2356 B/T cell crosstalk and aberrant inflammatory IgG exacerbate autoimmune intestinal inflammation

Gadjalova, I.; Heinze, J. M.; Goess, M. C.; Hofmann, J.; Albers, J. J.; Spallek, R.; Blissenbach, B.; Buck, A.; Weber, M.-C.; Scherer, E.; Kampick, M.; Oellinger, R.; Krut, O.; Rad, R.; Steiger, K.; Winter, C.; Janssen, K.-P.; Neumann, P.-A.; Geha, R. S.; Ruland, J.; Keppler, S. J.

10.1101/2022.09.12.507066 — immunology — Posted on 2022-09-15

2357 Negative regulation of C. elegans innate immunity by orphan nuclear receptor NHR-42

Goswamy, D.; Labed, S. A.; Gonzalez, X.; Irazoqui, J. E.

10.1101/2022.09.12.507697 — immunology — Posted on 2022-09-15

2358 Anchors for Time, Distance, and Magnitude in Virtual Movements

Gladhill, K. A.; Robinson, E. M.; Stanfield-Wiswell, C.; Bader, F.; Wiener, M.

10.1101/2022.09.12.507649 — neuroscience — Posted on 2022-09-15

2359 Altered plasma membrane abundance of the sulfatide-binding protein NF155 links glycosphingolipid imbalances to demyelination

McKie, S. J.; Nicholson, A. S.; Smith, E.; Fawke, S.; Caroe, E.; Williamson, J. C.; Butt, B. G.; Kolarov, D.; Peterka, O.; Holcapek, M.; Lehner, P. J.; Graham, S. C.; Deane, J. E.

10.1101/2022.09.15.508082 — neuroscience — Posted on 2022-09-15

2360 Modulation effect of non-invasive transcranial ultrasound stimulation in an ADHD rat model

Wang, M.; Wang, T.; Ji, H.; Yan, J.; Wang, X.; Zhang, X.; Li, X.; Yuan, Y.

10.1101/2022.09.12.507687 — neuroscience — Posted on 2022-09-15

2361 The effects of explicit and implicit information on modulation of corticospinal excitability during hand-object interactions.

Rens, G.; Davare, M.; van Polanen, V.

10.1101/2022.03.20.485033 — neuroscience — Posted on 2022-09-15

2362 Cortical glutamatergic projection neuron types contribute to distinct functional subnetworks

Mohan, H.; An, X.; Xu, X. H.; Kondo, H.; Zhao, S.; Matho, K. S.; Musall, S.; Mitra, P. P.; Huang, Z. J.

10.1101/2021.12.30.474537 — neuroscience — Posted on 2022-09-15

2363 TACI: an ImageJ plugin for 3D calcium imaging analysis

Omelchenko, A. A.; Bai, H.; Hussain, S.; Tyrrell, J. J.; Ni, L.

10.1101/2021.09.28.462182 — neuroscience — Posted on 2022-09-15

2364 A Systems Biology Approach to Pathogenesis of Gastric Cancer: Gene Network Modeling and Pathway Analysis

Mottaghi-Dastjerdi, N.; Ghorbani, A.; Montazeri, H.

10.1101/2022.09.12.507635 — systems biology — Posted on 2022-09-15

2365 Novel Small Molecular Compound AE-848 Showed Potent Inhibitory Activity Against Human Hepatoblastoma Cells

Wang, J.; Zhou, Q.; Sun, L.; Xu, Y.; Jiang, Y.; Liu, X.; Li, S.; Li, H.; Zheng, C.; Jie, G.

10.1101/2022.09.12.507704 — cancer biology — Posted on 2022-09-15

2366 grandR: a comprehensive package for nucleotide conversion sequencing data analysis

Rummel, T.; Sakellaridi, L.; Erhard, F.

10.1101/2022.09.12.507665 — bioinformatics — Posted on 2022-09-15

2367 Mathematical reconstruction of the metabolic network in an in-vitro multiple myeloma model.

Vera-Siguenza, E.; Escribano-Gonzalez, C.; Serrano-Gonzalo, I.; Eskla, K.-L.; Spill, F.; Tennant, D. A.

10.1101/2022.09.12.507672 — bioengineering — Posted on 2022-09-15

2368 Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy

Kadam, A. H.; Kandasamy, K.; Buss, T.; Cederstrom, B.; Yang, C.; Narayanapillai, S.; Rodriguez, J.; Levin, M. D.; Koziol, J.; Olenyuk, B.; Borok, Z.; Chrastina, A.; Schnitzer, J. E.

10.1101/2022.09.12.507679 — bioengineering — Posted on 2022-09-15

2369 Dispensing with unnecessary assumptions in population genetics analysis

Labayle, O.; Tetley-Campbell, K. J.; van der Laan, M. J.; Ponting, C. P.; Beentjes, S. V.; Khamseh, A.

10.1101/2022.09.12.507656 — genetics — Posted on 2022-09-15

2370 Dentate gyrus morphogenesis is regulated by β-CATENIN function in hem-derived fimbrial glia.

Parichha, A.; Datta, D.; Suresh, V.; Chatterjee, M.; Holtzman, M. J.; Tole, S.

10.1101/2022.09.15.508086 — neuroscience — Posted on 2022-09-15

2371 Synaptic Competition Enhances the Discrimination of Interfering Memories

Fung, C. C. A.; Fukai, T.

10.1101/2022.09.15.508061 — neuroscience — Posted on 2022-09-15

2372 Inconsistencies between human and macaque lesion data can be resolved with a stimulus-computable model of the ventral visual stream

Bonnen, T.; Eldridge, M. A. G.

10.1101/2022.09.12.507636 — neuroscience — Posted on 2022-09-15

2373 Modelling homeostatic plasticity in the auditory cortex results in neural signatures of tinnitus

Schultheiss, H.; Zulfiqar, I.; Moerel, M.

10.1101/2022.09.12.507667 — neuroscience — Posted on 2022-09-15

2374 A critical period for neurogenesis loss and cognitive decline in patients with mesial temporal lobe epilepsy patients

Ammothumkandy, A.; Corona, L.; Ravina, K.; Wolseley, V.; Jimenez, N.; Armacost, M.; D'Orazio, L. M.; Nelson, J.; Zuverza-Chavarria, V.; McCleary, C.; Nune, G.; Kalayjian, L.; Lee, D.; Lee, B.; Heck, C.; Chow, R. H.; Russin, J. J.; Liu, C. Y.; Smith, J. A.; Bonaguidi, M. A.

10.1101/2022.09.12.507339 — neuroscience — Posted on 2022-09-15

2375 The coarse mental map of the breast is anchored on the nipple

Long, K.; Fitzgerald, E.; Berger-Wolf, E.; Fawaz, A.; Greenspon, C.; Lindau, S.; Bensmaia, S. J.

10.1101/2022.09.14.507974 — neuroscience — Posted on 2022-09-15

2376 Haplotype resolved DNA methylome of African cassava genome

Zhong, Z.; Feng, S.; Mansfeld, B. N.; Ke, Y.; Qi, W.; Lim, Y.-W.; Gruissem, W.; Bart, R. S.; Jacobsen, S. E.

10.1101/2022.09.12.507674 — plant biology — Posted on 2022-09-15

2377 Practical guide to calculating impact of avidity in models of bispecific antibodies with two membrane-bound targets

Kareva, I.; Kabilan, S.; Zutshi, A.; Rhoden, J.

10.1101/2022.09.12.507653 — pharmacology and toxicology — Posted on 2022-09-15

2378 Molecular determinants of Karyopherin-β2 chaperone and disaggregation activity

Fare, C.; Rhine, K.; Lam, A.; Myong, S.; Shorter, J.

10.1101/2022.09.14.508025 — biochemistry — Posted on 2022-09-15

2379 A novel P{lacW} insertion in the CG18135 gene of Drosophila melanogaster is linked to pupal lethality and gene overexpression in adult males

Ionascu, A.; Ratiu, A. C.

10.1101/2022.09.13.507739 — genetics — Posted on 2022-09-15

2380 Decapentaplegic ligand ensures niche space restriction inside and outside of Drosophila testicular niche

Ridwan, S. M.; Twille, A.; Matsuda, S.; Antel, M.; Inaba, M.

10.1101/2022.09.13.507868 — developmental biology — Posted on 2022-09-15

2381 Nucleus of the lateral olfactory tract (NLOT): a hub linking water homeostasis-associated SON-AVP circuit and neocortical regions to promote social behavior under osmotic challenge

Hernandez-Perez, O. R.; Hernandez, V. S.; Zetter, M. A.; Eiden, L. E.; Zhang, L.

10.1101/2022.07.01.498472 — neuroscience — Posted on 2022-09-15

2382 Brain Structure and Episodic Learning Rate in Cognitively Healthy Ageing

Frank, D.; Garo-Pascual, M.; Reyes Velasquez, P. A.; Frades, B.; Peled, N.; Zhang, L.; Strange, B.

10.1101/2022.05.03.490431 — neuroscience — Posted on 2022-09-15

2383 Mapping the cellular and molecular organization of mouse cerebral aging by single-cell transcriptome imaging

Allen, W. E.; Blosser, T. R.; Sullivan, Z. A.; Dulac, C.; Zhuang, X.

10.1101/2022.09.14.508048 — neuroscience — Posted on 2022-09-15

2384 Single-cell characterisation of the hematopoietic bone marrow interactome in health and disease

Ennis, S.; Conforte, A.; O'Reilly, E.; Cichocka, T.; Pal Dhami, S.; Nicholson, P.; Krebs, P.; O Broin, P.; Szegezdi, E.

10.1101/2022.05.13.491790 — cancer biology — Posted on 2022-09-15

2385 An Inhibitory Function of TRPA1 Channels in TGF-β1-driven Fibroblast to Myofibroblast Differentiation

Geiger, F.; Zeitlmayr, S.; Staab-Weijnitz, C. A.; Rajan, S.; Breit, A.; Gudermann, T.; Dietrich, A.

10.1101/2022.04.12.488008 — cell biology — Posted on 2022-09-15

2386 Does ivermectin treatment for endemic hookworm infection alter the gut microbiota of endangered Australian sea lion pups?

Fulham, M.; Power, M. L.; Gray, R.

10.1101/2022.09.14.508058 — microbiology — Posted on 2022-09-15

2387 Collective protection against the type VI secretion system in bacteria

Granato, E. T.; Smith, W. P. J.; Foster, K. R.

10.1101/2022.09.12.507624 — microbiology — Posted on 2022-09-15

2388 Pharmacological manipulations of physiological arousal and sleep-like slow waves modulate sustained attention

Pinggal, E.; Dockree, P. M.; O'Connell, R. G.; Bellgrove, M. A.; Andrillon, T.

10.1101/2022.03.25.485866 — neuroscience — Posted on 2022-09-15

2389 Exogenous Cues Aid Salient Distractor Suppression and Enhance Attentional Prioritization during Visual Working Memory Encoding in Schizophrenia

Barnes-Scheufler, C. V.; Roesler, L.; Schaum, M.; Schiweck, C.; Peters, B.; Reif, A.; Wibral, M.; Bittner, R. A.

10.1101/2021.05.19.442954 — neuroscience — Posted on 2022-09-15

2390 Co-Delivery of Synergistic Antimicrobials with Polyelectrolyte Nanocomplexes to Treat Bacterial Biofilms and Lung Infections

Finbloom, J. A.; Raghavan, P.; Kwon, M.; Kharbikar, B. N.; Yu, M. A.; Desai, T. A.

10.1101/2021.11.22.469570 — bioengineering — Posted on 2022-09-15

2391 Study on the interactions between cisplatin and cadherin

Wang, X.; Sun, J.; Shao, K.-; Zhi, H.; Lin, Y.; Fu, Y.; Liu, Z.

10.1101/2022.09.11.507507 — biochemistry — Posted on 2022-09-15

2392 Different structural variant prediction tools yield considerably different results in Caenorhabditis elegans

Lesack, K.; Mariene, G. M.; Andersen, E. C.; Wasmuth, J. D.

10.1101/2022.03.11.483485 — genomics — Posted on 2022-09-15

2393 Using eDNA metabarcoding to establish targets for freshwater fish composition following river restoration

Ito, G.; Yamauchi, H.; Shigeyoshi, M.; Ashino, K.; Yonashiro, C.; Asami, M.; Goto, Y.; Duda, J. J.; Yamanaka, H.

10.1101/2022.05.26.493668 — ecology — Posted on 2022-09-15

2394 Experimental and theoretical aspects of Golden Gate Assembly assays

Strzelecki, P.; Shpiruk, A.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Hebraud, P.; Beyer, N.; Busi, F.; Grange, W.

10.1101/2022.09.09.507109 — molecular biology — Posted on 2022-09-15

2395 Modeling communication and switching nonlinear dynamics in multi-region neural activity

Karniol-Tambour, O.; Zoltowski, D. M.; Diamanti, E. M.; Pinto, L.; Tank, D. W.; Brody, C. W.; Pillow, J. W.

10.1101/2022.09.13.507841 — neuroscience — Posted on 2022-09-15

2396 Presynaptic Rac1 controls synaptic strength through the regulation of synaptic vesicle priming.

Keine, C.; Al-Yaari, M.; Radulovic, T.; Thomas, C. I.; Valino Ramos, P.; Guerrero-Given, D.; Ranjan, M.; Taschenberger, H.; Kamasawa, N.; Young, S. M.

10.1101/2022.06.29.497712 — neuroscience — Posted on 2022-09-15

2397 Sex-specific association between emotion negativity and neural processing of reward feedback in young children

Chung, Y. S.; Bagdasarov, A.; Gaffrey, M. S.

10.1101/2022.06.20.496831 — neuroscience — Posted on 2022-09-15

2398 Motor and cognitive deficits limit the ability to flexibly modulate spatiotemporal gait features in older adults with mild cognitive impairment

Rosenberg, M. C.; Slusarenko, A.; Cao, K.; McKay, J. L.; Emmery, L.; Kesar, T. M.; Hackney, M. E.

10.1101/2022.09.09.507368 — synthetic biology — Posted on 2022-09-15

2399 Molecular portraits of cell cycle checkpoint kinases in cancer evolution, progression, and treatment responsiveness

Oropeza, E.; Punturi, S.; Carrel, S. J.; Mazumder, A.; Jimenez, A.; VandenHeuvel, S. N.; Noltensmeyer, D. A.; Punturi, N.; Lei, J. T.; Lim, B.; Raghavan, S.; Bainbridge, M.; Haricharan, S.

10.1101/2020.10.29.361352 — cancer biology — Posted on 2022-09-15

2400 Unbiased pangenome graphs

Garrison, E.; Guarracino, A.

10.1101/2022.02.14.480413 — bioinformatics — Posted on 2022-09-15

2401 Optimal trade-off control in machine learning-based library design, with application to adeno-associated virus (AAV) for gene therapy

ZHU, D.; Brookes, D. H.; Busia, A.; Carneiro, A.; Fannjiang, C.; Popova, G.; Shin, D.; Chang, E. F.; Nowakowski, T. J.; Listgarten, J.; Schaffer, D. V.

10.1101/2021.11.02.467003 — bioengineering — Posted on 2022-09-15

2402 28 Minutes Later: A behavioral and transcriptomic investigation into the potential role of aflatrem-like compounds in establishing Ophiocordyceps extended phenotypes in zombie ants

Beckerson, W. C.; Krider, C.; Mohammad, U. A.; de Bekker, C.

10.1101/2022.09.08.507134 — animal behavior and cognition — Posted on 2022-09-15

2403 Human commensal Candida albicans strains demonstrate substantial within-host diversity and retained pathogenic potential

Anderson, F. M.; Visser, N.; Amses, K.; Hodgins-Davis, A.; Weber, A. M.; Metzner, K. M.; McFadden, M. J.; Mills, R. E.; O'Meara, M. J.; James, T. Y.; OMeara, T. R.

10.1101/2022.09.09.507247 — microbiology — Posted on 2022-09-15

2404 Learning vs. minding: How subjective costs can mask motor learning

Healy, C. M.; Berniker, M.; Ahmed, A. A.

10.1101/2022.02.11.479978 — neuroscience — Posted on 2022-09-15

2405 Polarly localized WPR proteins interact with PAN receptors and the actin cytoskeleton during maize stomatal development

Nan, Q.; Char, S. N.; Yang, B.; Bennett, E. J.; Yang, B.; Facette, M. R.

10.1101/2022.04.22.489215 — plant biology — Posted on 2022-09-15

2406 Physics-based generative model of curvature sensing peptides; distinguishing sensors from binders

van Hilten, N.; Methorst, J.; Verwei, N.; Risselada, H. J.

10.1101/2022.09.01.506157 — biophysics — Posted on 2022-09-15

2407 Chimera States among Synchronous Fireflies

Sarfati, R.; Peleg, O.

10.1101/2022.05.12.491720 — biophysics — Posted on 2022-09-15

2408 Open modification searching of SARS-CoV-2-human protein interaction data reveals novel viral modification sites

Adams, C.; Boonen, K.; Laukens, K.; Bittremieux, W.

10.1101/2022.03.10.483652 — bioinformatics — Posted on 2022-09-15

2409 Selection for translational efficiency in genes associated with alphaproteobacterial gene transfer agents

Kogay, R.; Zhaxybayeva, O.

10.1101/2022.06.17.496587 — evolutionary biology — Posted on 2022-09-15

2410 ATP hydrolysis tunes specificity of a AAA+ protease

Mahmoud, S. A.; Aldikacti, B.; Chien, P.

10.1101/2021.08.18.456811 — molecular biology — Posted on 2022-09-15

2411 Genomic analysis of extended-spectrum beta-lactamase (ESBL) producing Escherichia coli colonising adults in Blantyre, Malawi reveals previously undescribed diversity.

Lewis, J. M.; Mphasa, M.; Banda, R.; Beale, M. A.; Mallewa, J.; Anscombe, C.; Zuza, A.; Roberts, A. P.; Heinz, E.; Thomson, N. R.; Feasey, N. A.

10.1101/2021.10.07.463523 — microbiology — Posted on 2022-09-15

2412 Drosophila Cocaine Avoidance is Mediated by Peripheral Bitter Gustatory Neurons

Philyaw, T. J.; Titos, I.; Cummins, P. N.; Rodan, A. R.; Rothenfluh, A.

10.1101/2022.06.22.497211 — neuroscience — Posted on 2022-09-15

2413 Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O'Brien, D. P.; Jones, H. B.; Guenther, F.; Murphy, E. J.; England, K. S.; Anderson, M.; Brennan, P.; Davis, J. B.; Pinto-Fernandez, A.; Turnbull, A. P.; Kessler, B. M.

10.1101/2022.09.13.507798 — biochemistry — Posted on 2022-09-15

2414 Defining Cardiac Recovery at Single Cell Resolution

Amrute, J. M.; Lai, L.; Ma, P.; Koenig, A. L.; Kamimoto, K.; Bredemeyer, A.; Shankar, T. S.; Kuppe, C.; Kadyrov, F. F.; Schulte, L. J.; Stoutenburg, D.; Kopecky, B. J.; Navankasattusas, S.; Visker, J.; Morris, S. A.; Kramann, R.; Leuschner, F.; Mann, D. L.; Drakos, S. G.; Lavine, K. J.

10.1101/2022.09.11.507463 — genomics — Posted on 2022-09-15

2415 GIFT: New method for the genetic analysis of small gene effects involving small sample sizes.

Rauch, C.; Kyratzi, P.; Blott, S.; Bray, S.; Wattis, J.

10.1101/2022.02.25.479563 — genetics — Posted on 2022-09-15

2416 How development affects evolution

Gonzalez-Forero, M.

10.1101/2021.10.20.464947 — evolutionary biology — Posted on 2022-09-15

2417 Convergent community assembly among globally separated acidic cave biofilms

Jones, D. S.; Schaperdoth, I.; Northup, D. E.; Gomez-Cruz, R.; Macalady, J.

10.1101/2022.09.13.507874 — microbiology — Posted on 2022-09-15

2418 Central metabolism is a key player in E. coli biofilm stimulation by sub-MIC antibiotics

Yaeger, L. N.; French, S.; Brown, E. D.; Cote, J.-P.; Burrows, L. L.

10.1101/2022.09.14.507886 — microbiology — Posted on 2022-09-15

2419 Metadata preservation and stewardship for genomic data is possible, but must happen now

Crandall, E. D.; Toczydlowski, R. H.; Liggins, L.; Holmes, A. E.; Ghoojaei, M.; Gaither, M. R.; Wham, B. E.; Pritt, A. L.; Noble, C.; Anderson, T. J.; Barton, R. L.; Berg, J. T.; Beskid, S. G.; Delgado, A.; Farrell, E.; Himmelsbach, N.; Queeno, S. R.; Trinh, T.; Weyand, C. A.; Bentley, A.; Deck, J.; Riginos, C.; Bradburd, G. S.; Toonen, R. J.

10.1101/2022.09.12.507034 — bioinformatics — Posted on 2022-09-15

2420 Perilipin 3 promotes the formation of membrane domains enriched in diacylglycerol and lipid droplet biogenesis proteins

Khaddaj, R.; Schneiter, R.

10.1101/2022.09.14.507979 — cell biology — Posted on 2022-09-15

2421 Pseudocontact shift NMR data obtained from a non-canonical amino acid-linked lanthanide tag improves integral membrane protein structure prediction

Ledwitch, K. V.; Kuenze, G.; Larochelle, K.; Okwei, E. N. N.; Pankewitz, L.; Ganguly, S.; Darling, H. L.; Coin, I.; Meiler, J.

10.1101/2022.09.14.507970 — biophysics — Posted on 2022-09-15

2422 Molecular elucidation of drug-induced abnormal assemblies of the Hepatitis B Virus capsid protein by solid-state NMR

Lecoq, L.; Brigandat, L.; Huber, R.; Fogeron, M.-L.; Callon, M.; Malaer, A.; Wang, S.; Dujardin, M.; Briday, M.; Wiegand, T.; Durantel, D.; Burdette, D.; Berke, J.-M.; Meier, B. H.; Nassal, M.; Bockmann, A.

10.1101/2022.09.14.507909 — biophysics — Posted on 2022-09-15

2423 Comprehensive analysis of long non-coding RNAs in breast cancer using topic modeling.

Malagoli, G.; Valle, F.; Barillot, E.; Caselle, M.; Martignetti, L.

10.1101/2022.09.13.507779 — bioinformatics — Posted on 2022-09-15

2424 The persistent homology of mitochondrial ATP synthases

Sinha, S. D.; Wideman, J. G.

10.1101/2022.09.13.506888 — evolutionary biology — Posted on 2022-09-15

2425 Histone chaperone ASF1 mediates H3.3-H4 deposition in Arabidopsis

Zhong, Z.; Wang, Y.; Wang, M.; Yang, F.; Thomas, Q. A.; Xue, Y.; Zhang, Y.; Liu, W.; Jami-Alahmadi, Y.; Xu, L.; Feng, S.; Marquardt, S.; Wohlschlege, J. A.; Ausin, I.; Jacobsen, S. E.

10.1101/2022.09.12.507673 — plant biology — Posted on 2022-09-15

2426 The intrinsically disordered protein glue of myelin: Linking AlphaFold2 predictions to experimental data

Krokengen, O. C.; Raasakka, A.; Kursula, P.

10.1101/2022.09.13.507838 — biophysics — Posted on 2022-09-15

2427 Cryo-EM-based structural insights into supramolecular assemblies of γ-Hemolysin from Staphylococcus aureus reveal the pore formation mechanism.

Mishra, S.; Roy, A. K.; Dutta, S.

10.1101/2022.09.14.507916 — biophysics — Posted on 2022-09-15

2428 Binding of ATP to GroEL: a Case for Variable-Temperature Native Mass Spectrometry Thermodynamic Studies

Walker, T.; Sun, H. M.; Gunnels, T.; Wysocki, V.; Laganowsky, A.; Rye, H.; Russell, D. H.

10.1101/2022.09.13.507831 — biophysics — Posted on 2022-09-15

2429 Multiscale compression-induced restructuring of stacked lipid bilayers: from buckling delamination to molecular packing

Porras-Gomez, M.; Kim, H.; Dronadula, M. T.; Kambar, N.; Metellus, C. J. P.; Aluru, N. R.; van der Zande, A.; Leal, C.

10.1101/2022.09.12.507641 — biophysics — Posted on 2022-09-15

2430 Cryo-EM reveals the membrane binding phenomenon of EspB, a virulence factor of the Mycobacterial Type VII secretion system

Sengupta, N.; Padmanaban, S.; Dutta, S.

10.1101/2022.09.14.507925 — biophysics — Posted on 2022-09-15

2431 Expanding the repertoire of human tandem repeat RNA-binding proteins

Ormazabal, A.; Carletti, M. S.; Saldano, T. E.; Gonzalez-Buitron, M.; Marchetti, J.; Palopoli, N.; Bateman, A.

10.1101/2022.09.12.507642 — bioinformatics — Posted on 2022-09-15

2432 ACCELERATING ANTIBODY DESIGN WITH ACTIVE LEARNING

Seo, S.-w.; Kwak, M. W.; Kang, E.; Kim, C.; Park, E.; Kang, T. H.; Kim, J.

10.1101/2022.09.12.507690 — bioengineering — Posted on 2022-09-15

2433 Ants dynamically adjust liquid foraging strategies in response to biophysical constraints

Fujioka, H.; Marchand, M.; LeBoeuf, A. C.

10.1101/2022.09.13.507744 — animal behavior and cognition — Posted on 2022-09-15

2434 Quantification of spatial and phenotypic heterogeneity in an agent-based model of tumour-macrophage interactions

Bull, J. A.; Byrne, H. M.

10.1101/2022.05.26.493564 — systems biology — Posted on 2022-09-15

2435 Deficits in cerebellum-dependent learning and cerebellar morphology in male and female BTBR autism model mice

Kiffmeyer, E. A.; Cosgrove, J. A.; Siganos, J. K.; Bien, H. E.; Vipond, J. E.; Vogt, K. R.; Kloth, A. D.

10.1101/2022.09.14.507695 — neuroscience — Posted on 2022-09-15

2436 Elucidating polymorphs of crystal structures with intensity-based hierarchical clustering analysis on multiple diffraction datasets

Matsuura, H.; Sakai, N.; Toma-Fukai, S.; Muraki, N.; Hayama, K.; Kamikubo, H.; Aono, S.; Kawano, Y.; Yamamoto, M.; Hirata, K.

10.1101/2022.09.13.507775 — molecular biology — Posted on 2022-09-14

2437 Systematic mutagenesis reveals critical effector functions in the assembly and dueling of the H1-T6SS in Pseudomonas aeruginosa

Wu, L.-L.; Pei, T.-T.; Yan, S.; Tang, M.-X.; Wu, L.-W.; Li, H.; Liang, X.; Sun, S.; Dong, T.

10.1101/2022.09.14.507963 — microbiology — Posted on 2022-09-14

2438 In vitro Isolation of Treponema pallidum subsp. pallidum from Fresh and Frozen Needle Aspirates of Primary Experimental Syphilis Lesions

Tantalo, L. C.; Molini, B. J.; Bose, M.; Klausner, J. D.; Giacani, L.

10.1101/2022.09.13.507848 — microbiology — Posted on 2022-09-14

2439 Viroscope: plant viral diagnosis from NGS data using biologically-informed genome assembly coverage

Valenzuela, S. L.; Norambuena, T.; Morgante, V.; Garcia, F.; Jimenez, J. C.; Nunez, C.; Fuentes, I.; Pollak, B.

10.1101/2022.09.14.507814 — microbiology — Posted on 2022-09-14

2440 IL-1β turnover by TRIP12 and AREL1 ubiquitin ligases and UBE2L3 limits inflammation

Mishra, V.; Crespo-Puig, A.; McCarthy, C.; Masonou, T.; Glegola-Madejska, I.; Dejoux, A.; Dow, G.; Eldridge, M. J. G.; Marinelli, L. H.; Meng, M.; Wang, S.; Bennison, D. J.; Shenoy, A. R.

10.1101/2022.09.14.507790 — immunology — Posted on 2022-09-14

2441 Polymer physics of structural evolution in synthetic yeast chromosomes

Stracquadanio, G.; Yang, K.; Boeke, J. D.; Koszul, R.; Bader, J. S.

10.1101/2022.09.14.507906 — synthetic biology — Posted on 2022-09-14

2442 RUNX1-deficient human megakaryocytes demonstrate thrombopoietic and platelet half-life and functional defects in an in vivo murine model: Therapeutic implications

Lee, K.; Ahn, H. S.; Estevez, B.; Poncz, M.

10.1101/2022.09.12.507354 — cancer biology — Posted on 2022-09-14

2443 Identification of tubulin polymerization inhibitors with a CRISPR-edited cell line with endogenous fluorescent tagging of β-tubulin and Histone 1

Khachatryan, H.; Barrero, C. A.; Gordon, J.; Olszowy, B.; Perez-Leal, O.

10.1101/2022.09.14.507662 — cancer biology — Posted on 2022-09-14

2444 Pyro-Velocity: Probabilistic RNA Velocity inference from single-cell data

Qin, Q.; Bingham, E.; La Manno, G.; Langenau, D. M.; Pinello, L.

10.1101/2022.09.12.507691 — bioinformatics — Posted on 2022-09-14

2445 Functional comparison of full-length palladin to isolated actin binding domain

Albraiki, S. E.; Klausmeyer, R.; Ajiboye, O.; Beck, M. R.

10.1101/2022.09.14.507982 — biochemistry — Posted on 2022-09-14

2446 Capillary electrophoresis mass spectrometry identifies new isomers of inositol pyrophosphates in mammalian tissues

Qiu, D.; Gu, C.; Liu, G.; Ritter, K.; Eisenbeis, V. B.; Bittner, T.; Gruzdev, A.; Seidel, L.; Bengsch, B.; Shears, S. B.; Jessen, H.

10.1101/2022.09.14.507917 — biochemistry — Posted on 2022-09-14

2447 INTERACTION OF THE PERIPLASMIC CHAPERONE SURA WITH THE INNER MEMBRANE PROTEIN SECRETION (SEC) MACHINERY

Troman, L.; Alvira, S.; Daum, B.; Gold, V.; Collinson, I.

10.1101/2022.09.14.507990 — biochemistry — Posted on 2022-09-14

2448 Microsecond melting and revitrification of cryo samples with a correlative light-electron microscopy approach

Bongiovanni, G.; Harder, O. F.; Drabbels, M.; Lorenz, U. J.

10.1101/2022.09.14.507962 — biochemistry — Posted on 2022-09-14

2449 PLAE web app enables powerful searching and multiple visualizations across one million unified single-cell ocular transcriptomes

Swamy, V. S.; Batz, Z.; McGaughey, D. M.

10.1101/2022.09.12.507632 — genomics — Posted on 2022-09-14

2450 Functional interpretation, cataloging, and analysis of 1,341 known and new glucose-6-phosphate dehydrogenase variants

Geck, R. C.; Powell, N. R.; Dunham, M. J.

10.1101/2022.09.14.508023 — genetics — Posted on 2022-09-14

2451 Simple and rapid site-specific integration of multiple heterologous DNAs into the Escherichia coli chromosome

Riley, L. A.; Payne, I. C.; Tumen-Velasquez, M.; Guss, A. M.

10.1101/2022.09.13.507873 — genetics — Posted on 2022-09-14

2452 A Subtle Balance between Host Selection and Microbial Size Effect Mediates Plant Microbiome Assembly in Mulberry

He, J.; Shen, X.; Zhang, N.; Muhammad, A.; Shao, Y.

10.1101/2022.09.14.507911 — microbiology — Posted on 2022-09-14

2453 Novel lipid biomarkers for algal resistance to viral infection in the ocean

Schleyer, G.; Kuhlisch, C.; Ziv, C.; Ben-Dor, S.; Malitsky, S.; Schatz, D.; Vardi, A.

10.1101/2022.09.14.507897 — microbiology — Posted on 2022-09-14

2454 A Second Role for the Second Messenger Cyclic-di-GMP in E. coli: Arresting Cell Growth by Altering Metabolic Flow

Hwang, Y.; Harshey, R. M.

10.1101/2022.09.14.507988 — microbiology — Posted on 2022-09-14

2455 Biological and synthetic surfactant exposure increase anti-microbial gene occurrence in a freshwater mixed microbial biofilm environment

Gill, S. P.; Snelling, W. J.; Dooley, J. S.; Ternan, N. G.; Banat, I. M.; Arnscheidt, J.; Hunter, W. R.

10.1101/2022.09.14.507961 — microbiology — Posted on 2022-09-14

2456 Identification and characterization of thousands of bacteriophage satellites across bacteria

de Sousa, J. M.; Fillol-Salom, A.; Penades, J. R.; Rocha, E. P. C.

10.1101/2022.09.14.508007 — microbiology — Posted on 2022-09-14

2457 Structure-Function analysis of Lactiplantibacillus plantarum DltE reveals D-alanylated lipoteichoic acids as direct symbiotic cues supporting Drosophila juvenile growth

Nikolopoulos, N.; Matos, R. C.; Ravaud, S.; Courtin, P.; Akherraz, H.; Palussiere, S.; Gueguen-Chaignon, V.; Salomon-Mallet, M.; Guillot, A.; Guerardel, Y.; Chapot-Chartier, M.-P.; Grangeasse, C.; Leulier, F.

10.1101/2022.09.14.507969 — microbiology — Posted on 2022-09-14

2458 Interactions between metabolism and growth can determine the co-existence of Staphylococcus aureus and Pseudomonas aeruginosa

Pajon, C.; Fortoul, M. C.; Diaz-Tang, G.; Meneses, E. M.; Mariah, T.; Toscan, B.; Marcelin, M.; Lopatkin, A. J.; Eldakar, O. T.; Smith, R. P.

10.1101/2022.09.14.507888 — microbiology — Posted on 2022-09-14

2459 pWCP is a widely distributed and highly conserved Wolbachia plasmid in Culex mosquitoes worldwide

Ghousein, A.; Tutagata, J.; Etienne, M.; Chaumeau, V.; Boyer, S.; Pages, N.; Roiz, D.; Eren, A. M.; Cambray, G.; Reveillaud, J.

10.1101/2022.09.14.507914 — microbiology — Posted on 2022-09-14

2460 Visual evidence for the recruitment of four enzymes with RNase activity to the Bacillus subtilis replication forks

Hinrichs, R.; Graumann, P.

10.1101/2022.09.13.507877 — microbiology — Posted on 2022-09-14

2461 Leishmania amazonensis controls macrophage-regulated cell death to establish chronic infection in vitro and in vivo

Lecoeur, H.; Zhang, S.; Varet, H.; Legendre, R.; Proux, C.; Granjean, C.; Bousso, P.; Prina, E.; Spaeth, G. F.

10.1101/2022.09.14.507851 — microbiology — Posted on 2022-09-14

2462 The Diversity and Ubiquity of Antibiotic Resistant Genes in Finfish Culture Ponds in Bangladesh

Bell, A. G.; Thornber, K.; Chaput, D. L.; Hasan, N. A.; Alam, M. M.; Haque, M. M.; Cable, J.; Temperton, B.; Tyler, C. R.

10.1101/2022.09.14.507951 — microbiology — Posted on 2022-09-14

2463 Structural evolution of an immune evasion determinant shapes Lyme borreliae host tropism

10.1101/2022.09.13.507797 — microbiology — Posted on 2022-09-14

2464 Systematically attenuating DNA targeting enables CRISPR-driven editing in bacteria

Collias, D.; Vialetto, E.; Yu, J.; Co, K.; Almasi, E.; Ruettiger, A.-S.; Achmedov, T.; Strowig, T.; Beisel, C. L.

10.1101/2022.09.14.507927 — synthetic biology — Posted on 2022-09-14

2465 Analysis and comprehensive lineage identification for SARS-CoV-2 genomes through scalable learning methods

Cahuantzi, R.; Lythgoe, K.; Hall, I.; House, T. A.; Pellis, L.

10.1101/2022.09.14.507985 — bioinformatics — Posted on 2022-09-14

2466 Molecular engineering of a cryptic epitope in Spike RBD improves manufacturability and neutralizing breadth against SARS-CoV-2 variants

Rodriguez-Aponte, S. A.; Dalvie, N. C.; Wong, T. Y.; Johnston, R. S.; Naranjo, C. A.; Bajoria, S.; Kumru, O. S.; Kaur, K.; Russ, B. P.; Lee, K. S.; Cyphert, H. A.; Barbier, M.; Rao, H. D.; Rajurkar, M. P.; Lothe, R. R.; Shaligram, U.; Batwal, S.; Chandrasekaran, R.; Nagar, G.; Kleanthous, H.; Biswas, S.; Bevere, J. R.; Joshi, S. B.; Volkin, D. B.; Damron, F. H.; Love, J. C.

10.1101/2022.09.14.507842 — bioengineering — Posted on 2022-09-14

2467 EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes

Richter, D. J.; Berney, C.; Strassert, J. F. H.; Poh, Y.-P.; Herman, E. K.; Munoz-Gomez, S. A.; Wideman, J. A.; Burki, F.; de Vargas, C.

10.1101/2020.06.30.180687 — evolutionary biology — Posted on 2022-09-14

2468 Variation in mutation, recombination, and transposition rates in Drosophila melanogaster and Drosophila simulans

Wang, Y.; McNeil, P.; Abdulazeez, R.; Pascual, M.; Johnston, S. E.; Keightley, P. D.; Obbard, D. J.

10.1101/2022.09.12.507595 — evolutionary biology — Posted on 2022-09-14

2469 PARNAS: Objectively Selecting the Most Representative Taxa on a Phylogeny

Markin, A.; Wagle, S.; Grover, S.; Vincent Baker, A. L.; Eulenstein, O.; Anderson, T. K.

10.1101/2022.09.12.507613 — evolutionary biology — Posted on 2022-09-14

2470 MATEdb, a data repository of high-quality metazoan transcriptome assemblies to accelerate phylogenomic studies

Fernandez, R.; Tonzo, V.; Simon Guerrero, C.; Lozano-Fernandez, J.; Martinez-Redondo, G. I.; Balart-Garcia, P.; Aristide, L.; Eleftheriadi, K.; Vargas-Chavez, C.

10.1101/2022.07.18.500182 — evolutionary biology — Posted on 2022-09-14

2471 Adversarial interspecies relationships facilitate population suppression by gene drive in spatially explicit models

Liu, Y.; Teo, W.; Yang, H.; Champer, J.

10.1101/2022.05.08.491087 — ecology — Posted on 2022-09-14

2472 The SARS-CoV-2 spike N-terminal domain engages 9-O-acetylated α2-8-linked sialic acids

Tomris, I.; Unione, L.; Nguyen, L.; Zaree, P.; Bouwman, K. M.; Liu, L.; Li, Z.; Fok, J. A.; Rios Carrasco, M.; van der Woude, R.; Kimpel, A. L. M.; Linthorst, M. W.; Verpalen, E. C. J. M.; Caniels, T. G.; Sanders, R. W.; Heesters, B. A.; Pieters, R. J.; Jimenez-Barbero, J.; Klassen, J. S.; Boons, G.-J.; de Vries, R. P.

10.1101/2022.09.14.507904 — molecular biology — Posted on 2022-09-14

2473 A novel fluorobenzothiazole RBx 10080758 as a dual inhibitor against bacterial GyraseB (GyrB) and Topoisomerase IV (parE) of Gram-positive pathogens causing skin and respiratory infections

Barman, T.; Kumar, M.; Chaira, T.; Singhal, S.; Mathur, T.; Kalia, V.; Gangadharan, R.; Rao, M.; Pandya, M.; Bhateja, P.; Sood, R.; Upadhyay, D.; Varughese, S.; Yadav, A.; Sharma, L.; Kumar, N.; Sattigeri, J.; Bhatnagar, P. K.; Raj, V. S.

10.1101/2022.09.08.507076 — microbiology — Posted on 2022-09-14

2474 HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era

Buhler, S.; Calderin, Z.; Bettens, F.; Schaefer, A.; Dantin, C.; Ansari, M.; Mamez, A.-C.; Masouridi-Levrat, S.; Chalandon, Y.; Ferrari-Lacraz, S.; Villard, J.

10.1101/2022.09.14.507948 — immunology — Posted on 2022-09-14

2475 Structure and Epitope of a Neutralizing Monoclonal Antibody that Targets the Stem Helix of β Coronaviruses

Deshpande, A.; Schormann, N.; Piepenbrink, M. S.; Martinez-Sobrido, L.; Kobie, J.; Walter, M. R.

10.1101/2022.09.14.507947 — immunology — Posted on 2022-09-14

2476 Monocyte-derived peritoneal macrophages protect C57BL/6 mice against surgery-induced adhesions

Sahputra, R.; Dejyong, K.; Woolf, A.; Mack, M.; Allen, J. E.; Ruckerl, D.; Herrick, S.

10.1101/2022.07.12.499772 — immunology — Posted on 2022-09-14

2477 A method to estimate the cellular composition of the mouse brain from heterogeneous datasets

Rodarie, D.; Veraszto, C.; Roussel, Y.; Reimann, M.; Keller, D.; Ramaswamy, S.; Markram, H.; Gewaltig, M.-O.

10.1101/2021.11.20.469384 — neuroscience — Posted on 2022-09-14

2478 Validation and Establishment of a SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a pre-screening tool for the Plaque Reduction Neutralization Test

Merluza, J.; Ung, J.; Makowski, K.; Robinson, A.; Manguiat, K. J.; Mueller, N.; Audet, J.; Chen, J. C.-y.; Strong, J. E.; Wood, H.; Bello, A.

10.1101/2022.09.13.507876 — scientific communication and education — Posted on 2022-09-14

2479 Jovian enables direct inference of germline haplotypes from short reads via sequence-to-sequence modeling

O'Fallon, B. D.; Bolia, A.; Durtschi, J.; Yang, L.; Noble, K.; Frederickson, E.; Best, H.; Coleman, J.

10.1101/2022.09.12.506413 — bioinformatics — Posted on 2022-09-14

2480 The performance of deep generative models for learning joint embeddings of single-cell multi-omics data

Brombacher, E.; Hackenberg, M.; Kreutz, C.; Binder, H.; Treppner, M.

10.1101/2022.06.06.494951 — bioinformatics — Posted on 2022-09-14

2481 Intranasal oxytocin enhances social preference for parents over peers in male but not female peri- adolescent California mice (Peromyscus californicus)

Guoynes, C. D.; Marler, C. A.

10.1101/2022.09.12.507587 — animal behavior and cognition — Posted on 2022-09-14

2482 The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

Moulana, A.; Dupic, T.; Phillips, A. M.; Chang, J.; Roffler, A. A.; Greaney, A. J.; Starr, T. N.; Bloom, J. D.; Desai, M. M.

10.1101/2022.09.13.507781 — evolutionary biology — Posted on 2022-09-14

2483 Transplantable human thyroid organoids generated from embryonic stem cells to rescue hypothyroidism

Romitti, M.; Tourneur, A.; de Faria da Fonseca, B.; Doumont, G.; Gillotay, P.; Liao, x.-h.; Eski, S. E.; Van Simaeys, G.; Chomette, L.; Lasolle, h.; Monestier, O.; Figini Kasprzyk, D.; Detours, V.; Singh, S. P.; Goldman, S.; Refetoff, S.; Costagliola, S.

10.1101/2021.12.01.470729 — developmental biology — Posted on 2022-09-14

2484 An Arp2/3-cPLA2-NFkB axis acts as a Cell Shape Sensor to drive Homeostatic Migration of Dendritic Cells

Alraies, Z.; Rivera, C. A.; Delgado, M.-G.; Sanseau, D.; Maurin, M.; Yatim, A.; Saez, P.; Williart, A.; Gratia, M.; DeSilva, N.; Moreau, A.; Albaud, B.; Legoix, P.; Nakano, H.; Cook, D. N.; Lawrence, T.; Manel, N.; D. Moreau, H.; Nader, G. P. F.; Piel, M.; Lennon-Dumenil, A.-M.

10.1101/2022.08.09.503223 — cell biology — Posted on 2022-09-14

2485 Nanobody engineering for SARS-CoV-2 neutralization and detection

Hannula, L.; Kuivanen, S.; Lasham, J.; Kant, R.; Kareinen, L.; Bogacheva, M.; Strandin, T.; Sironen, T.; Sharma, V.; Saviranta, P.; Kipar, A.; Vapalahti, O.; Huiskonen, J. T.; Rissanen, I.

10.1101/2022.09.14.507920 — microbiology — Posted on 2022-09-14

2486 Trans-synaptic dwelling of SARS-CoV-2 particles perturbs neural synapse organization and function

Partiot, E.; Hirschler, A.; Colomb, S.; Lutz, W.; Claeys, T.; Delalande, F.; Deffieu, M. S.; Roels, J.; Bons, J.; Callon, D.; Andreoletti, L.; Labrousse, M.; Jacobs, F. M.; Rigau, V.; Charlot, B.; Martens, L.; Carapito, C.; Ganesh, G.; Gaudin, R.

10.1101/2022.09.13.507484 — microbiology — Posted on 2022-09-14

2487 Characterization of the cytopathic effect of monkeypox virus isolated from clinical specimens and differentiation from common viral exanthems

Ma, A.; Hanson, K. E.; Langer, J.; Bradley, B. T.

10.1101/2022.09.13.507875 — microbiology — Posted on 2022-09-14

2488 Kinase-independent activity of DYRK1A promotes viral entry of highly pathogenic human coronaviruses

Strine, M. S.; Cai, W. L.; Wei, J.; Alfajaro, M. M.; Filler, R. B.; Biering, S. B.; Sarnik, S.; Patil, A.; Cervantes, K. S.; Collings, C. K.; DeWeirdt, P. C.; Hanna, R. E.; Schofield, K.; Hulme, C.; Konermann, S.; Doench, J. G.; Hsu, P. D.; Kadoch, C.; Yan, Q.; Wilen, C. B.

10.1101/2022.09.13.507833 — microbiology — Posted on 2022-09-14

2489 Reactivation-induced memory integration prevents proactive interference in perceptual learning

Huang, Z.; Niu, Z.; Li, S.

10.1101/2022.09.01.506161 — neuroscience — Posted on 2022-09-14

2490 Meggie - easy-to-use graphical user interface for M/EEG analysis based on MNE-python

Heinila, E.; Parviainen, T.

10.1101/2022.09.12.507592 — neuroscience — Posted on 2022-09-14

2491 Neural Representations of Post-Decision Choice Confidence and Reward Expectation in the Caudate Nucleus and Frontal Eye Field

Fan, Y.; Doi, T.; Gold, J. I.; Ding, L.

10.1101/2022.09.12.507621 — neuroscience — Posted on 2022-09-14

2492 A machine learning approach to identify the engagement of a brain network targeted by non-invasive brain-stimulation

Shinde, A.; Mohapatra, S.; Schlaug, G.

10.1101/2022.09.12.507591 — neuroscience — Posted on 2022-09-14

2493 Effect of Nitrogen Fertilizer Rate on Yield and Quality Parameters of Malt Barley Varieties for Beer Production in South Gonder, Ethiopia

Abebe, A. A.; Hagos, F.

10.1101/2022.09.12.507533 — plant biology — Posted on 2022-09-14

2494 A protocol for rapid generation cycling (speed breeding) of hemp (Cannabis sativa) for research and agriculture

Schilling, S.; Melzer, R.; Dowling, C. A.; Shi, J.; Muldoon, S.; McCabe, P. F.

10.1101/2022.09.12.507554 — plant biology — Posted on 2022-09-14

2495 Maize integrates light and volatile cues from neighboring plants into unique defense responses

Escobar-Bravo, R.; Schimmel, B. C.; Zhang, Y.; Robert, C. A.; Glauser, G.; Ballare, C. L.; Erb, M.

10.1101/2022.09.12.507519 — plant biology — Posted on 2022-09-14

2496 Evolutionary metabolomics of specialized metabolism diversification in the genus Nicotiana highlights allopolyploidy-mediated innovations in N-acylnornicotine metabolism

Elser, D.; Pflieger, D.; Villette, C.; Moegle, B.; Miesch, L.; Gaquerel, E.

10.1101/2022.09.12.507566 — plant biology — Posted on 2022-09-14

2497 Comparing the efficiency of six clearing methods in developing seeds of Arabidopsis thaliana

Attuluri, V. P. S.; Sanchez Lopez, J. F.; Maier, L.; Paruch, K.; Robert, H. S.

10.1101/2022.09.12.507557 — plant biology — Posted on 2022-09-14

2498 SARS-CoV-2 Protein Nsp2 Stimulates Translation Under Normal and Hypoxic Conditions

Korneeva, N.; Khalil, M. I.; Ghosh, i.; Fan, R.; Arnold, T.; De Benedetti, A.

10.1101/2022.09.13.507829 — physiology — Posted on 2022-09-14

2499 Co-targeting BCL-XL and MCL-1 with DT2216 and AZD8055 synergistically inhibits small-cell lung cancer growth without causing on-target toxicities in mice

KHAN, S.; Kellish, P.; Connis, N.; Thummuri, D.; Wiegand, J.; Zhang, P.; Zhang, X.; Budamagunta, V.; Hua, N.; Yang, Y.; De, U.; Jin, L.; Zhang, W.; Zheng, G.; Hromas, R.; Hann, C.; Zajac-Kaye, M.; Kaye, F. J.; Zhou, D.

10.1101/2022.09.12.507616 — cancer biology — Posted on 2022-09-14

2500 Predicting 3D genome architecture directly from the nucleotide sequence with DNA-DDA

Lainscsek, X.; Taher, L.

10.1101/2022.09.12.507578 — bioinformatics — Posted on 2022-09-14

2501 CimpleG: Finding simple CpG methylation signatures

Maie, T.; Schmidt, M.; Erz, M.; Wagner, W.; Gesteira Costa Filho, I.

10.1101/2022.09.12.507513 — bioinformatics — Posted on 2022-09-14

2502 Genozip 14 - advances in compression of BAM and CRAM files

Lan, D. M.; Llamas, B.

10.1101/2022.09.12.507582 — bioinformatics — Posted on 2022-09-14

2503 Modelling group heteroscedasticity in single-cellRNA-seq pseudo-bulk data

You, Y.; Dong, X.; Wee, Y. K.; Maxwell, M. J.; Alhamdoosh, M.; Smyth, G.; Hickey, P. F.; Ritchie, M. E.; Law, C. W.

10.1101/2022.09.12.507511 — bioinformatics — Posted on 2022-09-14

2504 Measuring Capillary Flow Dynamics using Interlaced Two-Photon Volumetric Scanning

Giblin, J.; Park, S.-W.; Jiang, J.; Kilic, K.; Kura, S.; Boas, D. A.; Chen, I. A.

10.1101/2022.09.12.507580 — bioengineering — Posted on 2022-09-14

2505 Photoselective sequencing: microscopically-guided genomic measurements with subcellular resolution

Mangiameli, S. M.; Chen, H.; Earl, A. S.; Dobkin, J.; Lesman, D.; Buenrostro, J. D.; Chen, F.

10.1101/2022.09.12.507600 — genomics — Posted on 2022-09-14

2506 Function of cell adhesion molecules in differentiation of ray sensory neurons in C. elegans.

Sakai, N.; Sun, P.; Kim, B.; Emmons, S. W.

10.1101/2022.09.12.507584 — genetics — Posted on 2022-09-14

2507 A possible genomic footprint of polygenic adaptation on population divergence in seed beetles?

Arnqvist, G.; Sayadi, A.

10.1101/2022.09.12.507575 — evolutionary biology — Posted on 2022-09-14

2508 Pea-adapted biotype of the aphid Acyrthosiphon pisum induces susceptibility of pea to non-adapted biotype enabling improved feeding and performance

Shih, P.-Y.; Ollivier, R.; Cherqui, A.; Ameline, A.; Morliere, S.; Outreman, Y.; Simon, J.-C.; Sugio, A.

10.1101/2022.09.12.507464 — ecology — Posted on 2022-09-14

2509 Predicting host associations of the invasive spotted lanternfly on trees across the USA

Huron, N. A.; Helmus, M. R.

10.1101/2022.09.12.507604 — ecology — Posted on 2022-09-14

2510 The Ecosystem Pressure-Volume Curve

Binks, O.; Meir, P.; Mencuccini, M.

10.1101/2022.09.12.507627 — ecology — Posted on 2022-09-14

2511 Mangroves deviate from other angiosperms in their genome size, leaf cell size, and cell packing density relationships

Jiang, G.-F.; Li, S.-Y.; Dinnage, R.; Cao, K.-F.; Simonin, K.; Roddy, A.

10.1101/2022.09.12.507581 — ecology — Posted on 2022-09-14

2512 An Arrayed Transposon Library of Ruegeria pomeroyi DSS-3

Mejia, C.; Trujillo Rodriguez, L.; Poudel, R.; Ellington, A.; Rivers, A. R.; Reisch, C.

10.1101/2022.09.11.507510 — microbiology — Posted on 2022-09-14

2513 Developmental instability of CA1 pyramidal cells in Dravet Syndrome

P. Jones, S.; O'Neill, N.; Muggeo, S.; Colasante, G.; Kullmann, D. M.; Lignani, G.

10.1101/2022.09.12.507264 — neuroscience — Posted on 2022-09-14

2514 Action prediction error: a value-free dopaminergic teaching signal that drives stable learning

Greenstreet, F.; Vergara, H. M.; Pati, S.; Schwarz, L.; Wisdom, M.; Marbach, F.; Johansson, Y.; Rollik, L.; Moskovitz, T.; Clopath, C. M.; Stephenson-Jones, M.

10.1101/2022.09.12.507572 — neuroscience — Posted on 2022-09-14

2515 Joint cmICA: auto-linking of structural and functional connectivity

Wu, L.; Calhoun, V.

10.1101/2022.09.12.507415 — neuroscience — Posted on 2022-09-14

2516 Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex

Zou, X.; Shanmugam, S. K.; Kanner, S. A.; Sampson, K. J.; Kass, R. S.; Colecraft, H. M.

10.1101/2022.09.12.507626 — physiology — Posted on 2022-09-14

2517 Cuproptosis is correlated with clinical status, tumor immune microenvironment and immunotherapy in colorectal cancer: a multi-omic analysis

Shao, Y.; Fan, X.; Yang, X.; Li, S.; Huang, L.; Zhou, X.; Zhang, S.; Zheng, M.; Sun, J.

10.1101/2022.09.12.507555 — cancer biology — Posted on 2022-09-14

2518 Quantification of membrane binding and diffusion using Fluorescence Correlation Spectroscopy diffusion laws

Mouttou, A.; Bremaud, E.; Noero, J.; Dibsy, R.; Arone, C.; Mak, J.; MURIAUX, D.; Berry, H.; Favard, C.

10.1101/2022.09.12.507540 — biophysics — Posted on 2022-09-14

2519 Optimization and redevelopment of single-cell data analysis workflow based on deep generative models

Liu, Y.; Fu, Q.; Dong, C.; Xia, X.; Liu, G.; Liu, L.

10.1101/2022.09.12.507562 — bioinformatics — Posted on 2022-09-14

2520 Functional impairment of the Lateral Geniculate Nucleus in Multiple Sclerosis

Sardaripour, N.; Asadi, M.; Moghaddam, H. A.; Khadem, A.; Rajimehr, R.

10.1101/2022.09.12.506825 — bioengineering — Posted on 2022-09-14

2521 Development of human lateral prefrontal sulcal morphology and its relation to reasoning performance

Willbrand, E. H.; Ferrer, E.; Bunge, S. A.; Weiner, K. S.

10.1101/2022.09.14.507822 — neuroscience — Posted on 2022-09-14

2522 ARTseq-FISH reveals position-dependent fate decisions driven by cell cycle changes

Hu, X.; van Sluijs, B.; Garcia Blay, O.; Stepanov, Y.; Rietrae, K.; Huck, W.; Hansen, M. M. K.

10.1101/2022.09.14.507902 — systems biology — Posted on 2022-09-14

2523 Measuring the similarity of SMLM-derived point-clouds

Baragilly, M.; Nieves, D.; Williamson, D.; Peters, R.; Owen, D.

10.1101/2022.09.12.507560 — biophysics — Posted on 2022-09-14

2524 Real-time TIRF imaging of exocytosis in 3T3-L1 adipocytes stably expressing mCherry fused to human adiponectin.

Shrestha, M. M.; Barg, S.; Olofsson, C. S.

10.1101/2022.09.13.507762 — cell biology — Posted on 2022-09-14

2525 Creating an atlas of the bone microenvironment during oral inflammatory-related bone disease using single-cell profiling

Fan, Y.; Lyu, P.; Bi, R.; Cui, C.; Xu, R.; Rosen, C. J.; Yuan, Q.; Zhou, C.

10.1101/2022.09.13.507807 — cell biology — Posted on 2022-09-14

2526 Pbp1 stabilizes and promotes the translation of Puf3-target mRNAs involved in mitochondrial biogenesis

van de Poll, F.; Sutter, B. M.; Lee, C.-D.; Yang, Y.-S.; Tu, B. P.

10.1101/2022.09.14.507933 — cell biology — Posted on 2022-09-14

2527 Steric-free bioorthogonal profiling of cellular acetylation and glycosylation via a fluorine-selenol displacement reaction (FSeDR)

Zhao, Y.; Zhao, M.; Lyu, Z.; Gorman, N.; Lewis, T.; Goldman, A. R.; Tang, H.-Y.; Wang, R. E.

10.1101/2022.09.13.507737 — cell biology — Posted on 2022-09-14

2528 Organization of Upstream ESCRT Machinery at the HIV-1 Budding Site

Hudait, A.; Hurley, J. H.; Voth, G. A.

10.1101/2022.09.13.507863 — biophysics — Posted on 2022-09-14

2529 Working strokes produced by curling protofilaments at disassembling microtubule tips can be biochemically tuned and vary with species

Murray, L. E.; Kim, H.; Rice, L. M.; Asbury, C. L.

10.1101/2022.09.13.507824 — biophysics — Posted on 2022-09-14

2530 Evolutionary trajectories are contingent on mitonuclear interactions

Biot-Pelletier, D.; Bettinazzi, S.; Gagnon-Arsenault, I.; Dube, A. K.; Bedard, C.; Nguyen, T. H. M.; Fiumera, H.; Breton, S.; Landry, C.

10.1101/2022.09.11.507487 — evolutionary biology — Posted on 2022-09-14

2531 Neutrophils regulate ITPR2 levels in epithelia by direct injection of elastase

Ogino, N.; Leite, M. F.; Kruglov, E.; Asashima, H.; Hafler, D. A.; Ehrlich, B. E.; Nathanson, M.

10.1101/2022.09.13.506588 — cell biology — Posted on 2022-09-14

2532 Teneurin-2 at the Synapse Construction Site is a Signpost for Cargo Unloading from Motor Proteins

Ichinose, S.; Susuki, Y.; Kaneko, R.; Iwasaki, H.

10.1101/2022.09.13.507723 — cell biology — Posted on 2022-09-14

2533 SiGra: Single-cell spatial elucidation through image-augmented graph transformer

Tang, Z.; Zhang, T.; Yang, B.; Su, J.; Song, Q.

10.1101/2022.08.18.504464 — bioinformatics — Posted on 2022-09-14

2534 Phenotypic variation, additive genetic variation, and trait divergence in two sister species of cheilostome bryozoans

Leventhal, S. E.; Jamison-Todd, S.; Simpson, C.

10.1101/2021.12.09.471970 — evolutionary biology — Posted on 2022-09-14

2535 Immediate early proteins of herpes simplex virus transiently repress viral transcription before subsequent activation

Dunn, L. E. M.; Birkenheuer, C. H.; Dufour, R.; Baines, J. D.

10.1101/2022.06.13.495981 — microbiology — Posted on 2022-09-14

2536 RatInABox: A toolkit for modelling locomotion and neuronal activity in continuous environments

George, T. M.; de Cothi, W.; Clopath, C.; Stachenfeld, K.; Barry, C.

10.1101/2022.08.10.503541 — neuroscience — Posted on 2022-09-14

2537 Basolateral amygdala astrocytes are engaged by the acquisition and expression of a contextual fear memory

Suthard, R. L.; Senne, R. A.; Buzharsky, M. D.; Cole, R. H.; Ramirez, S.

10.1101/2022.09.11.507456 — neuroscience — Posted on 2022-09-14

2538 Comparing the representation of a simple visual stimulus across the cerebellar network

Prat, O.; Petrucco, L.; Stih, V.; Portugues, R.

10.1101/2022.09.12.507660 — neuroscience — Posted on 2022-09-14

2539 FX-Cell: Quantitative cell release from fixed plant tissues for single-cell genomics

Marchant, D. B.; Nelms, B.; Walbot, V.

10.1101/2021.10.11.463960 — plant biology — Posted on 2022-09-14

2540 How important are functional and developmental constraints on phenotypic evolution? An empirical test with the stomatal anatomy of flowering plants

Muir, C. D.; Conesa, M. A.; Galmes, J.; Pathare, V. S.; Rivera, P.; Rodriguez, R. L.; Terrazas, T.; Xiong, D.

10.1101/2021.09.02.457988 — plant biology — Posted on 2022-09-14

2541 The sequence compositional complexity of the coronavirus decays over pandemic time

Oliver, J. L.; Bernaola-Galvan, P.; Perfectti, F.; Gomez-Martin, C.; Castiglione, S.; Raia, P.; Verdu, M.; Moya, A.

10.1101/2021.11.06.467547 — genomics — Posted on 2022-09-14

2542 Bimodal breeding phenology in the parsley frog Pelodytes punctatus as a bet-hedging strategy in an unpredictable environment despite strong priority effects

Jourdan-Pineau, H.; Crochet, P.-A.; David, P.

10.1101/2022.02.24.481784 — evolutionary biology — Posted on 2022-09-14

2543 SARS-CoV-2 hijacks p38β/MAPK11 to promote viral protein translation

Higgins, C. A.; Nilsson-Payant, B. E.; Kurland, A.; Ye, C.; Yaron, T. M.; Johnson, J. L.; Bonaventure, B.; Adhikary, P.; Golynker, I.; Rosenberg, B. R.; Danziger, O.; Panis, M.; Cantley, L. C.; Martinez-Sobrido, L.; tenOever, B. R.; Johnson, J. R.

10.1101/2021.08.20.457146 — microbiology — Posted on 2022-09-14

2544 Synaptotagmin 9 modulates spontaneous neurotransmitter release in striatal neurons by regulating substance P secretion

Seibert, M. J.; Evans, C. S.; Stanley, K. S.; Wu, Z.; Chapman, E. R.

10.1101/2022.04.18.488681 — neuroscience — Posted on 2022-09-14

2545 Follicle cell contact maintains main body axis polarity in the Drosophila melanogaster oocyte

Milas, A.; de-Carvalho, J.; Telley, I. A.

10.1101/2022.03.03.482911 — developmental biology — Posted on 2022-09-14

2546 Paecilomycone inhibits quorum sensing in Gram-negative bacteria

Beenker, W. A.; Hoeksma, J.; Marie Bannier-Helaouët, M.; Clevers, H.; den Hertog, J.

10.1101/2022.09.12.507720 — microbiology — Posted on 2022-09-14

2547 Hydrogen Peroxide Production by Epidermal Dual Oxidase 1 Regulates Nociceptive Sensory Signals

Pato, A.; Bölcskei, K.; Donko, A.; Kaszas, D.; Boros, M.; Bodrogi, L.; Varady, G.; Pape, V. F.; Roux, B.; Enyedi, B.; Helyes, Z.; Watt, F. M.; Sirokmany, G.; Geiszt, M.

10.1101/2022.09.11.507480 — physiology — Posted on 2022-09-14

2548 Quantum Biology in Cellular Migration

Vecheck, A.; McNamee, C.; Reijo Pera, R. A.; Usselman, R.

10.1101/2022.09.09.507322 — biophysics — Posted on 2022-09-14

2549 A generalizable framework to comprehensively predict epigenome, chromatin organization, and transcriptome

Zhang, Z.; Feng, F.; Qiu, Y.; Liu, J.

10.1101/2022.05.23.493129 — bioinformatics — Posted on 2022-09-14

2550 Experimental evaluation of environmental DNA methods for detection of a rare fish in turbid water

Holmes, A. E.; Baerwald, M. R.; Rodzen, J. A.; Schreier, B. M.; Mahardja, B.; Finger, A. J.

10.1101/2022.08.24.502857 — molecular biology — Posted on 2022-09-14

2551 Evidence for a Single Rather than a Triple Dissociation in the Medial Temporal Lobe: an fMRI Recognition Memory Replication Study

Van, J.; Nielsen, S. E.; Kirwan, B.

10.1101/2022.04.14.488400 — neuroscience — Posted on 2022-09-14

2552 Anatomical and neurophysiological data on primary visual cortex suffice for reproducing brain-like robust multiplexing of visual function

Chen, G.; Scherr, F.; Maass, W.

10.1101/2021.12.07.471653 — neuroscience — Posted on 2022-09-14

2553 Hourglass, a tool to mine bioimaging data, uncovers sex-disparities in the IL-6-associated T cell response in pancreatic tumors

Aliar, K.; Waterhouse, H. R.; Vyas, F.; Krebs, N.; Poulton, E.; Zhang, B.; Chan, N.; Bronsert, P.; Fischer, S. E.; Gallinger, S.; Grünwald, B. T.; Khokha, R.

10.1101/2022.09.12.507618 — cancer biology — Posted on 2022-09-14

2554 Fluorescence Lifetime: Beating the IRF and interpulse window

Fazel, M.; Vallmitjana, A.; Scipioni, L.; Gratton, E.; Digman, M. A.; Presse, S.

10.1101/2022.09.08.507224 — biophysics — Posted on 2022-09-14

2555 The Statistical Trends of Protein Evolution: A Lesson from AlphaFold Database

Tang, Q.-Y.; Ren, W.; Wang, J.; Kaneko, K.

10.1101/2022.04.07.487447 — biophysics — Posted on 2022-09-14

2556 Bacterial lipoxygenases are associated with host-microbe interactions and may provide cross-kingdom host jumps

Kurakin, G.

10.1101/2022.06.21.497025 — bioinformatics — Posted on 2022-09-14

2557 Sequence-based Optimized Chaos Game Representation and Deep Learning for Peptide/Protein Classification

Huang, B.; Zhang, E.; Chaudhari, R.; Gimperlein, H.

10.1101/2022.09.10.507145 — bioinformatics — Posted on 2022-09-14

2558 Cryo-electron tomography reveals the multiplex anatomy of condensed native chromatin and its unfolding by histone citrullination

Jentink, N.; Purnell, C.; Kable, B.; Swulius, M. T.; Grigoryev, S. A.

10.1101/2022.07.11.499179 — molecular biology — Posted on 2022-09-14

2559 Understanding changes in genetic literacy over time and in genetic research participants

Little, I. D.; Koehly, L. M.; Gunter, C.

10.1101/2022.09.12.507568 — genetics — Posted on 2022-09-14

2560 Genomic evidence of natural selection for ash dieback resistance

Metheringham, C. L.; Plumb, W.; Stocks, J.; Kelly, L.; Nemesio Gorriz, M.; Moat, J.; Buggs, R.; Nichols, R. A.

10.1101/2022.08.01.502033 — evolutionary biology — Posted on 2022-09-14

2561 Evaluating drivers of spatiotemporal individual condition of a bottom-associated marine fish

Lindmark, M.; Anderson, S. C.; Gogina, M.; Casini, M.

10.1101/2022.04.19.488709 — ecology — Posted on 2022-09-14

2562 Homeostatic Synaptic Plasticity Rescues Neural Coding Reliability

Rozenfeld, E.; Ehmann, N.; Manoim, J. E.; Kittel, R.; Parnas, M.

10.1101/2021.12.06.471391 — neuroscience — Posted on 2022-09-14

2563 CTNND2 moderates neuronal excitation and links human evolution to prolonged synaptic development in the neocortex

Assendorp, N. M.; Depp, M.; Fossati, M.; Dingli, F.; Loew, D.; Charrier, C.

10.1101/2022.09.13.507776 — neuroscience — Posted on 2022-09-14

2564 Vowel and formant representation in human auditory speech cortex

Oganian, Y.; Bhaya-Grossman, I.; Johnson, K.; Chang, E. F.

10.1101/2022.09.13.507547 — neuroscience — Posted on 2022-09-14

2565 Long-distance linguistic dependencies in Chinese and English brains

Dunagan, D.; Stanojevic, M.; Coavoux, M.; Zhang, S.; Bhattasali, S.; Li, J.; Brennan, J.; Hale, J. T.

10.1101/2022.09.12.507571 — neuroscience — Posted on 2022-09-14

2566 Phase alignment of low-frequency neural activity to the amplitude envelope of speech reflects evoked responses to acoustic edges, not oscillatory entrainment

Oganian, Y.; Kojima, K.; Breska, A.; Cai, C.; Findlay, A.; Chang, E. F.; Nagarajan, S.

10.1101/2020.04.02.022616 — neuroscience — Posted on 2022-09-14

2567 A comparison of marker gene selection methods for single-cell RNA sequencing data

Pullin, J. M.; McCarthy, D. J.

10.1101/2022.05.09.490241 — bioinformatics — Posted on 2022-09-14

2568 Mapping the Constrained Coding Regions in the human genome to their corresponding proteins

Hasenahuer, M. A.; Sanchis-Juan, A.; Laskowski, R. A.; Baker, J. A.; Stephenson, J. D.; Orengo, C. A.; Raymond, F. L.; Thornton, J. M.

10.1101/2022.09.12.507545 — bioinformatics — Posted on 2022-09-14

2569 MoDLE: High-performance stochastic modeling of DNA loop extrusion interactions

Rossini, R.; Kumar, V.; Mathelier, A.; Rognes, T.; Paulsen, J.

10.1101/2022.04.13.488157 — bioinformatics — Posted on 2022-09-14

2570 slendr: a framework for spatio-temporal population genomic simulations on geographic landscapes

Petr, M.; Haller, B. C.; Ralph, P. L.; Racimo, F.

10.1101/2022.03.20.485041 — genomics — Posted on 2022-09-14

2571 The catheterized bladder environment promotes Efg1- and Als1-dependent Candida albicans infection

La Bella, A. A.; Andersen, M. J.; Gervais, N.; Molina, J. J.; Molesan, A.; Stuckey, P. V.; Wensing, L.; Nobile, C. J.; Shapiro, R. S.; Santiago-Tirado, F. H.; Flores-Mireles, A. L.

10.1101/2021.06.01.446547 — microbiology — Posted on 2022-09-14

2572 Development and applications of a CRISPR activation system for facile genetic overexpression in Candida albicans

Gervais, N. C.; La Bella, A. A.; Wensing, L. F.; Sharma, J.; Acquaviva, V.; Best, M.; Cadena Lopez, R. O.; Fogal, M.; Uthayakumar, D.; Chavez, A.; Santiago-Tirado, F.; Flores-Mireles, A. L.; Shapiro, R. S.

10.1101/2022.08.15.501889 — microbiology — Posted on 2022-09-14

2573 Cell-free Protein Crystallization for Nanocrystal Structure Determination

Abe, S.; Tanaka, J.; Kojima, M.; Kanamaru, S.; Hirata, K.; Yamashita, K.; Kobayashi, A.; Ueno, T.

10.1101/2022.04.15.488232 — biophysics — Posted on 2022-09-14

2574 Learning Continuous Potentials from smFRET

Bryan, J. S.; Presse, S.

10.1101/2022.09.12.507719 — biophysics — Posted on 2022-09-13

2575 Continuous millisecond conformational cycle of a DEAH box helicase reveals control of domain motions by atomic-scale transitions

Becker, R. A.; Hub, J. S.

10.1101/2022.09.13.507788 — biophysics — Posted on 2022-09-13

2576 Role of UCP2 in the energy metabolism of the cancer cell line A549

Segales, J.; Sanchez-Martin, C.; Pujol, A.; Martin-Ruiz, M.; Rial, E.

10.1101/2022.09.13.507778 — biochemistry — Posted on 2022-09-13

2577 Robust residue-level error detection in cryo-electron microscopy models

Reggiano, G.; Farrell, D.; DiMaio, F.

10.1101/2022.09.12.507680 — biochemistry — Posted on 2022-09-13

2578 Biosynthesis of iridoid sex pheromones in aphids

Koellner, T. G.; David, A.; Luck, K.; Beran, F.; Kunert, G.; Zhou, J.-J.; Caputi, L.; O'Connor, S. E.

10.1101/2022.09.13.507830 — biochemistry — Posted on 2022-09-13

2579 MATR3-antisense LINE1 RNA meshwork scaffolds higher-order chromatin organization

Zhang, Y.; Cao, X.; Gao, Z.; Ma, X.; Wang, Q.; Cai, X.; Zhang, Y.; Zhang, Z.; Wei, G.; Wen, B.

10.1101/2022.09.13.506124 — cell biology — Posted on 2022-09-13

2580 ArfGAP1 regulates the endosomal sorting of guidance receptors to promote directed collective cell migration in vivo

Boutet, A.; Zeledon, C.; Emery, G.

10.1101/2022.09.13.507825 — cell biology — Posted on 2022-09-13

2581 Antisense transcription of the Neurospora frequency gene is rhythmically regulated by CSP-1 repressor but dispensable for clock function

Cemel, I. A.; Diernfellner, A. C. R.; Brunner, M.

10.1101/2022.09.13.507755 — molecular biology — Posted on 2022-09-13

2582 Chemokine Signaling Caused by Mycobacterium avium Biofilms in the Lung Airway Increases Bacterial Loads by Spatially Diverting Macrophages

Weathered, C.; Pennington, K.; Escalante, P.; Pienaar, E.

10.1101/2022.09.13.507811 — systems biology — Posted on 2022-09-13

2583 The role of evolutionarily metastable oligomeric states in the optimization of catalytic activity

East, N. J.; Clifton, B. E.; Jackson, C. J.; Kaczmarski, J. A.

10.1101/2022.09.13.507756 — biochemistry — Posted on 2022-09-13

2584 Reaction pathways for the enzymatic degradation of poly(ethylene terephthalate): What characterizes an efficient PET-hydrolase?

Schubert, S.; Schaller, K.; Baath, J. A.; Hunt, C.; Borch, K.; Jensen, K.; Brask, J.; Westh, P.

10.1101/2022.09.13.507771 — biochemistry — Posted on 2022-09-13

2585 Recycling upstream redox enzymes expands the regioselectivity of cycloaddition in pseudo-aspidosperma alkaloid biosynthesis

Kamileen, M. O.; DeMars, M.; Hong, B.; Nakamura, Y.; Paetz, C.; Lichman, B. R.; Sonawane, P. D.; Caputi, L.; O'Connor, S. E.

10.1101/2022.09.13.507834 — biochemistry — Posted on 2022-09-13

2586 Computationally Guided Design of Two Novel Soluble Epoxide Hydrolase Inhibitors

Dere, E. C.; Chu, S. S.; Ortega, T.; Huang, P.; Siegel, J. B.

10.1101/2022.09.13.507703 — biochemistry — Posted on 2022-09-13

2587 Ultrahigh-throughput Absorbance Activated Droplet Sorting (UHT-AADS) for enzyme screening at kilohertz frequencies

Medcalf, E. J.; Gantz, M.; Kaminski, T. S.; Hollfelder, F.

10.1101/2022.09.13.507731 — biochemistry — Posted on 2022-09-13

2588 Metabolic Signatures of Performance in Elite World Tour Professional Cyclists

Nemkov, T.; Cendali, F.; Stefanoni, D.; Martinez, J.; Hansen, K. C.; San-Millan, I.; D'Alessandro, A.

10.1101/2022.09.13.507793 — biochemistry — Posted on 2022-09-13

2589 Single-cell transcriptomic profiling of kidney fibrosis identifies a novel specific fibroblast marker and putative disease target

Rudman-Melnick, V.; Adam, M.; Stowers, K.; Potter, A.; Ma, Q.; Chokshi, S. M.; Vanhoutte, D.; Valiente-Alandi, I.; Lindquist, D. M.; Nieman, M. L.; Kofron, J. M.; Potter, S. S.; Devarajan, P.

10.1101/2022.09.13.507855 — molecular biology — Posted on 2022-09-13

2590 Bacterial Argonaute proteins aid cell division in the presence of topoisomerase inhibitors in Escherichia coli

Olina, A.; Agapov, A.; Yudin, D.; Kuzmenko, A.; Aravin, A. A.; Kulbachiskiy, A.

10.1101/2022.09.13.507849 — molecular biology — Posted on 2022-09-13

2591 A gene expression analysis and immune infiltration between lesioned and preserved subchondral bone in osteoarthritis

Qin, Y.; Zhang, G.; Yin, C.; Wu, R.; Wang, R.; Lyu, S.

10.1101/2022.09.12.507705 — molecular biology — Posted on 2022-09-13

2592 Formation of amyloid loops in brain tissues is controlled by the flexibility of protofibril chains

Miller, A. M.; Meehan, S.; Dobson, C. M.; Welland, M. E.; Klenerman, D.; Vendruscolo, M.; Ruggeri, F. S.; Knowles, T. P. J.

10.1101/2022.09.13.507729 — molecular biology — Posted on 2022-09-13

2593 ZMYM2 is essential for methylation of germline genes and active transposons in embryogenesis

Graham-Paquin, A.-L.; Saini, D.; Sirois, J.; Hossain, I.; Katz, M. S.; Zhuang, Q. K.-W.; Kwon, S. Y.; Yamanaka, Y. A.; Bourque, G.; Bouchard, M.; Pastor, W. A.

10.1101/2022.09.13.507699 — molecular biology — Posted on 2022-09-13

2594 Imbalance of peptidoglycan biosynthesis alters the cell surface charge of Listeria monocytogenes

Schulz, L. M.; Rothe, P.; Halbedel, S.; Gründling, A.; Rismondo, J.

10.1101/2022.09.13.507711 — microbiology — Posted on 2022-09-13

2595 Isolation, culture and characterization of Arsenophonus symbionts from two insect species reveal loss of infectious transmission and extended host range in the apicola-nasoniae group.

Nadal-Jimenez, P.; Parratt, S. R.; Siozios, S.; Hurst, G. D. D.

10.1101/2022.09.13.507752 — microbiology — Posted on 2022-09-13

2596 Microcosm cultures of a complex synthetic community reveal ecology and genetics of gut microbial organization

Jin, X.; Yu, F. B.; Yan, J.; Weakley, A.; Pollard, K. S.

10.1101/2022.09.13.507837 — microbiology — Posted on 2022-09-13

2597 The Respiratory Syncytial Virus G Protein Enhances the Immune Responses to the RSV F Protein in an Enveloped Virus-like Particle Vaccine Candidate

McGinnes-Cullen, L. W.; Luo, B.; Wen, Z.; Zang, L.; Durr, E.; Morrison, T. G.

10.1101/2022.09.12.507712 — microbiology — Posted on 2022-09-13

2598 Extensions of mean-field approximations for environmentally-transmitted pathogen networks

Davies, K.; Lenhart, S.; Day, J.; Lloyd, A. L.; Lanzas, C.

10.1101/2022.09.13.507803 — microbiology — Posted on 2022-09-13

2599 SPRAY-INDUCED GENE SILENCING IDENTIFIES PATHOGEN PROCESSES CONTRIBUTING TO POWDERY MILDEW PROLIFERATION

McRae, A. G.; Taneja, J.; Yee, K.; Shi, X.; Haridas, S.; LaButti, K.; Singan, V.; Grigoriev, I. V.; Wildermuth, M. C.

10.1101/2022.09.13.507682 — microbiology — Posted on 2022-09-13

2600 A flexible and efficient microfluidics platform for the characterization and isolation of novel bacteriophages

Sidi Mabrouk, A.; Ongenae, V.; Claessen, D.; Brenzinger, S.; Briegel, A.

10.1101/2022.09.13.507764 — microbiology — Posted on 2022-09-13

2601 Integrons, plasmids, and resistance genes in equine faecal bacteria

Mitchell, S.; Moran, R. A.; Elbourne, L.; Chapman, B.; Bull, M.; Muscatello, G.; Coleman, N. V.

10.1101/2022.09.12.507718 — microbiology — Posted on 2022-09-13

2602 High throughput Bioluminescent assay to characterize and monitor the activity of SARS-CoV-2 Methyltransferases

Hsiao, K.; Zegzouti, H.; Goueli, S. A.

10.1101/2022.09.12.505486 — biochemistry — Posted on 2022-09-13

2603 Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

O'Brien, D. P.; Jones, H. B.; Guenther, F.; Murphy, E. J.; England, K. S.; Pinto-Fernandez, A.; Anderson, M.; Brennan, P.; Davis, J. B.; Turnbull, A. P.; Kessler, B. M.

10.1101/2022.09.13.507798 — biochemistry — Posted on 2022-09-13

2604 IL-10 suppresses T cell expansion while promoting tissue-resident memory cell formation during SARS-CoV-2 infection in rhesus macaques

Nelson, C. E.; Foreman, T. W.; Kauffman, K. D.; Sakai, S.; Fleegle, J. D.; Gomez, F.; NIAID/DIR Tuberculosis Imaging Program, ; Le Nouen, C.; Liu, X.; Burdette, T. L.; Garza, N. L.; Lafont, B. A. P.; Brooks, K.; Arlehamn, C. S. L.; Weiskopf, D.; Sette, A.; Hickman, H. D.; Buchhholz, U. J.; Johnson, R. F.; Brenchley, J. M.; Via, L. E.; Barber, D. L.

10.1101/2022.09.13.507852 — immunology — Posted on 2022-09-13

2605 Dark accumulation of downstream glycolytic intermediates confers robust initiation of photosynthesis in cyanobacteria

Tanaka, K.; Shirai, T.; Vavricka, C. J.; Matsuda, M.; Kondo, A.; Hasunuma, T.

10.1101/2022.04.04.486922 — plant biology — Posted on 2022-09-13

2606 Nitrogen availability and plant functional composition modify biodiversity-multifunctionality relationships

Pichon, N. A.; Cappelli, S. L.; Soliveres, S.; Mannall, T.; Nwe, T. Z.; Hölzel, N.; Klaus, V. H.; Kleinebecker, T.; Vincent, H.; Allan, E.

10.1101/2020.08.17.254086 — ecology — Posted on 2022-09-13

2607 Does Vaping Increase the Likelihood of SARS-CoV-2 Infection? Paradoxically Yes and No

Phandthong, R.; Wong, M.; Song, A.; Martinez, T.; Talbot, P.

10.1101/2022.09.09.507373 — cell biology — Posted on 2022-09-13

2608 Bivalent SARS-CoV-2 mRNA vaccines increase breadth of neutralization and protect against the BA.5 Omicron variant

Scheaffer, S. M.; Lee, D.; Whitener, B.; Ying, B.; Wu, K.; Jani, H.; Martin, P.; Amato, N. J.; Avena, L. E.; Berrueta, D. M.; Schmidt, S. D.; O'Dell, S.; Nasir, A.; Chuang, G.-Y.; Stewart-Jones, G.; Koup, R. A.; Doria-Rose, N. A.; Carfi, A.; Elbashir, S. M.; Thackray, L. B.; Edwards, D. K.; Diamond, M. S.

10.1101/2022.09.12.507614 — microbiology — Posted on 2022-09-13

2609 Monitoring correlates of SARS-CoV-2 infection in cell culture using two-photon microscopy and a novel fluorescent calcium-sensitive dye

Domokos, M.; Szalay, G.; Cseri, L.; Kis, Z.; Palyi, B.; Foldes, G.; Kovacs, N.; Fulop, A.; Szepesi, A.; Hajdrik, P.; Csomos, A.; Zsembery, A.; Kadar, K.; Katona, G.; Mucsi, Z.; Rozsa, B. J.; Kovacs, E.

10.1101/2022.09.12.506773 — microbiology — Posted on 2022-09-13

2610 Comparative multi-OMICS single-cell atlas of five COVID-19 (rAdVV and mRNA) vaccines describe unique and distinct mechanisms of action

Singh, Y.; Schulze-Selting, A.; Gabernet, G.; Ray, U.; Bajaj, R.; Ali, M.; Loitz, M.; Hammer, V.; Buena-Atienza, E.; Ruschil, C.; Huebner, J.; Kowarik, M.; salker, M.; Casadei, N.; Nahnsen, S.; Kremsner, P.; Ossowski, S.; Altmann, D. M.; Deutsche COVID-19 OMICS Initiative (DeCOI), ; Riess, O.

10.1101/2022.09.12.507666 — immunology — Posted on 2022-09-13

2611 Humoral immunogenicity of a Coronavirus Disease 2019 (COVID-19) DNA Vaccine in Rhesus Macaques (Macaca mulatta) Delivered using Needle-free Jet Injection

Jay, A.; Kwilas, S. A.; Josleyn, M.; Ricks, K.; Hooper, J. W.

10.1101/2022.09.12.507647 — immunology — Posted on 2022-09-13

2612 Evaluation of endogenous and therapeutic 25-hydroxycholesterols in murine models of pulmonary SARS-CoV-2 infection

Fessler, M. B.; Madenspacher, J.; Baker, P. J.; Hilligan, K. L.; Castro, E.; Meacham, J.; Chen, S.-H.; Johnson, R. F.; Martin, N. P.; Tucker, C. J.; Mahapatra, D.; Cesta, M.; Mayer-Barber, K. D.

10.1101/2022.09.12.507671 — immunology — Posted on 2022-09-13

2613 Assembling highly repetitive Xanthomonas TALomes using Oxford Nanopore sequencing

Erkes, A.; Grove, R.; Zarkovic, M.; Krautwurst, S.; Koebnik, R.; Morgan, R. D.; Wilson, G. G.; Hölzer, M.; Marz, M.; Boch, J.; Grau, J.

10.1101/2022.08.17.504259 — bioinformatics — Posted on 2022-09-13

2614 Chemical effects on ecological interactions within a model-experiment loop

Lamonica, D.; CHARLES, S.; Clement, B.; Lopes, C.

10.1101/2022.05.24.493191 — ecology — Posted on 2022-09-13

2615 A cortico-collicular circuit for accurate orientation to shelter during escape

Campagner, D.; Vale, R.; Tan, Y. L.; Iordanidou, P.; Arocas, O. P.; Claudi, F.; Stempel, A. V.; Keshavarzi, S.; Petersen, R.; Margrie, T.; Branco, T.

10.1101/2020.05.26.117598 — neuroscience — Posted on 2022-09-13

2616 DENVIS: scalable and high-throughput virtual screening using graph neural networks with atomic and surface protein pocket features

Krasoulis, A.; Antonopoulos, N.; Pitsikalis, V.; Theodorakis, S.

10.1101/2022.03.17.484710 — bioinformatics — Posted on 2022-09-13

2617 Network-based multi-omics integration reveals metabolic at-risk profile within treated HIV-infection

Mikaeloff, F.; Gelpi, M.; Benfeitas, R.; Knudsen, A. D.; Vestad, B.; Hogh, J.; Hov, J.; Benfield, T.; Murray, D.; Giske, C. G.; Mardinoglu, A.; Troseid, M.; Poulsen, S. D.; Neogi, U.

10.1101/2022.06.08.495246 — bioinformatics — Posted on 2022-09-13

2618 Biomolecular Condensate Regulates Enzymatic Activity under Crowded Milieu: Synchronization of Liquid-Liquid Phase separation and Enzymatic Transformation

Saini, B.; Mukherjee, T. K.

10.1101/2022.06.16.496378 — biochemistry — Posted on 2022-09-13

2619 Differential contributions of nuclear lamina association and genome compartmentalization to gene regulation

Das, P.; San Martin, R.; McCord, R. P.

10.1101/2022.09.12.507606 — genomics — Posted on 2022-09-13

2620 The relationship between spectral and plant diversity: disentangling the influence of metrics and habitat types

Perrone, M.; Di Febbraro, M.; Conti, L.; Divisek, J.; Chytry, M.; Keil, P.; Carranza, M. L.; Rocchini, D.; Torresani, M.; Moudry, V.; Simova, P.; Prajzlerova, D.; Müllerova, J.; Wild, J.; Malavasi, M.

10.1101/2022.09.05.506583 — ecology — Posted on 2022-09-13

2621 Mitochondrial Derived Vesicles retain membrane potential and contain a functional ATP synthase

Hazan (Ben-Menachem), R.; Lintzer, D.; Ziv, T.; Das, K.; Rosenhek-Goldian, I.; Porat, Z.; Ben Ami Pilo, H.; Karniely, S.; Saada, A.; Regev-Rudzki, N.; Pines, O.

10.1101/2022.07.10.499450 — cell biology — Posted on 2022-09-13

2622 Sensory convergence and inhibitory divergence: deep dorsal horn inhibitory interneurons modulate the timing and magnitude of limb coordination during locomotion.

Ozeri-Engelhard, N.; Gradwell, M. A.; Laflamme, O. D.; Upadhyay, A.; Aoki, A.; Shrier, T.; Gandhi, M.; Gonzalez, M.; Eisdorfer, J. T.; Abbas- Zadeh, G.; Yusuf, N.; Imtiaz, Z.; Alomary, S.; Katz, J.; Haas, M.; Hernandez, Y.; Akay, T.; Abraira, V. E.

10.1101/2022.05.21.492933 — neuroscience — Posted on 2022-09-13

2623 Beyond winglets: evolution of flight-related morphology in stick insects (Phasmatodea)

Zeng, Y.; Park, S.; Gonzales, C.; Yom, S.; Rahim, F.; Dudley, R.

10.1101/2022.06.09.495408 — evolutionary biology — Posted on 2022-09-13

2624 CCDC66 regulates primary cilium length and signaling competence via multi-site interactions with transition zone and axonemal proteins

Conkar, D.; Odabasi, E.; Deretic, J.; Batman, U.; Frikstad, K.-A. M.; Patzke, S.; Firat-Karalar, E. N.

10.1101/2022.04.10.487777 — cell biology — Posted on 2022-09-13

2625 Method Comparison for Japanese Encephalitis Virus Detection in Samples Collected from the Indo-Pacific Region

Crispell, G. P.; Williams, K. P.; Zielinski, E.; Iwami, A.; Homas, Z.; Thomas, K. E.

10.1101/2022.06.07.495224 — molecular biology — Posted on 2022-09-13

2626 The hidden diversity of ancient bornaviral sequences from X and P genes in vertebrate genomes

Garcia, B. C. B.; Mukai, Y.; Tomonaga, K.; Horie, M.

10.1101/2022.05.06.490909 — microbiology — Posted on 2022-09-13

2627 Development of a new 3D tracking system for multiple marmosets under free-moving conditions

Yurimoto, T.; Kumita, W.; Sato, K.; Kikuchi, R.; Shibuki, Y.; Hashimoto, R.; Kamioka, M.; Hayasegawa, Y.; Yamazaki, E.; Kurotaki, Y.; Goda, N.; Kitakami, J.; Fujita, T.; Inoue, T.; Sasaki, E.

10.1101/2022.03.29.486138 — animal behavior and cognition — Posted on 2022-09-13

2628 Deep selection shapes the intragenomic diversity of rRNA genes

Sultanov, D.; Hochwagen, A.

10.1101/2022.03.28.486124 — genomics — Posted on 2022-09-13

2629 Probabilistic Matrix Factorization for Gene Regulatory Network Inference

Mahmood, O.; Skok Gibbs, C.; Bonneau, R.; Cho, K.

10.1101/2022.09.09.507305 — genomics — Posted on 2022-09-13

2630 Non-trivial dynamics in a model of glial membrane voltage driven by open potassium pores

Janjic, P.; Solev, D.; Kocarev, L.

10.1101/2022.07.22.501179 — biophysics — Posted on 2022-09-13

2631 Clustering and finite size effects in a two-species exclusion process

Chacko, J.; Muhuri, S.; Tripathy, G.

10.1101/2022.09.10.507392 — biophysics — Posted on 2022-09-13

2632 Ehrlichia ruminantium uses its transmembrane protein Ape to adhere to host bovine aortic endothelial cells

Pinarello, V.; Bencurova, E.; Marcelino, I.; Gros, O.; Puech, C.; Bhide, M.; Vachiery, N.; MEYER, D. F.

10.1101/2021.06.15.447525 — microbiology — Posted on 2022-09-13

2633 Genetic deletion and pharmacologic inhibition of FcER1 reduces renal injury in mouse models of diabetic nephropathy.

Rashmi, P.; Silva, A. A.; Sigdel, T.; Damm, I.; Gouvea, A. L. F.; Koliwad, S.; Walavalkar, V.; Hakroush, S.; Sarwal, M. M.

10.1101/2022.09.10.507433 — immunology — Posted on 2022-09-13

2634 Tumor microenvironments impair T cell receptor affinity and function

Yuan, Z.; O'Melia, M. J.; Li, K.; Lyu, J.; Zhou, F.; Jothikumar, P.; Rohner, N. A.; Manspeaker, M. P.; Francis, D. M.; Bai, K.; Ge, C.; Rushdi, M. N.; Chingozha, L.; Ruiperez-Campillo, S.; Lu, H.; Thomas, S. N.; Zhu, C.

10.1101/2022.09.11.507496 — immunology — Posted on 2022-09-13

2635 Time-resolved dynamic computational modeling of human EEG recordings reveals gradients of generative mechanisms for the MMN response

Poublan-Couzardot, A.; Lecaignard, F.; Fucci, E.; Davidson, R. J.; Mattout, J.; Lutz, A.; Abdoun, O.

10.1101/2022.09.12.507526 — neuroscience — Posted on 2022-09-13

2636 Differential role of dopamine D3 receptor through balanced modulation of Akt/mTOR and ERK1/2 activity in the reactivation of cocaine rewarding memories evoked by psychological versus physiological stress

Franco-Garcia, A.; Guerrero-Bautista, R.; Hidalgo, J.; Milanes, M. V.; Gomez-Murcia, V.; Nunez, C.

10.1101/2022.09.12.507553 — neuroscience — Posted on 2022-09-13

2637 Octopamine and tyramine signaling in Aedes aegypti: characterization, distribution and potential role in the Dengue vector development and physiology

Finetti, L.; Paluzzi, J.-P.; Orchard, I.; Lange, A. B.

10.1101/2022.09.10.507408 — zoology — Posted on 2022-09-13

2638 The parthenogenesis mechanism and venom complement of the parasitoid wasp Microctonus hyperodae, a declining biocontrol agent.

Inwood, S. N.; Harrop, T. W. R.; Dearden, P. K.

10.1101/2022.09.11.507509 — zoology — Posted on 2022-09-13

2639 Time-scaled phylogenetic analysis of the Lamiini, its close relatives and some other widely distributed tribes of Lamiinae (Coleoptera, Cerambycidae)

Soydabas-Ayoub, H. K.; Uckan, F.

10.1101/2022.09.10.507409 — zoology — Posted on 2022-09-13

2640 Transcriptome analysis of the necrotrophic pathogen Alternaria brassicae reveals a biphasic mode of pathogenesis in Brassica juncea

Rajarammohan, S.

10.1101/2022.09.12.507536 — plant biology — Posted on 2022-09-13

2641 Subjective assessment and taste strips testing of gustatory function, at home, and in the lab

Green, T.; Wolf, A.; Oleszkiewicz, A.; Aronis, A.; Hummel, T.; Pepino, M. Y.; Niv, M. Y.

10.1101/2022.09.11.507407 — physiology — Posted on 2022-09-13

2642 The different effect of pharmacological or low-doses of IFN-γ in endothelial cells are mediated by different intracellular signaling pathways

Cazzaniga, A.; Miranda, V.; Castiglioni, S.; Maier, J. A. M.

10.1101/2022.09.13.507745 — pharmacology and toxicology — Posted on 2022-09-13

2643 Genetic perturbation of MAPK11 (p38β) promotes radiosensitivity by enhancing IR-associated senescence.

Fernandez-Aroca, D. M.; Garcia-Flores, N.; Frost, S.; Jimenez-Suarez, J.; Rodriguez-Gonzalez, A.; Fernandez-Aroca, P.; Sabater, S.; Andres, I.; Garnes-Garcia, C.; Belandia, B.; Cimas, F. J.; Villar, D.; Ruiz-Hidalgo, M. J.; Sanchez-Prieto, R.

10.1101/2022.09.12.506954 — cancer biology — Posted on 2022-09-13

2644 Quantifying coexistence concentrations in multi-component phase-separating systems using analytical HPLC

Bremer, A.; Posey, A. E.; Borgia, M. B.; Borcherds, W. M.; Farag, M.; Pappu, R. V.; Mittag, T.

10.1101/2022.09.11.507495 — biophysics — Posted on 2022-09-13

2645 Thermodynamic analysis of the GASright transmembrane motif supports energetic model of dimerization

Vazquez, G. D.; Cui, Q.; Senes, A.

10.1101/2022.07.11.499632 — biophysics — Posted on 2022-09-13

2646 Designing DNA-based predictors of drug response using the signal joint with gene expression

Mourragui, S.; Loog, M.; van Nee, M.; van de Wiel, M. A.; Reinders, M.; Wessels, L.

10.1101/2022.09.11.507473 — bioinformatics — Posted on 2022-09-13

2647 CLT-seq as a universal homopolymer-sequencing concept reveals poly(A)-tail-tuned ncRNA regulation

Su, Q.; Long, Y.; Wang, J.; Gou, D.

10.1101/2022.09.11.507502 — bioinformatics — Posted on 2022-09-13

2648 An impedance-based chemiresistor for the real-time detection of gut microbiota-generated short-chain fatty acids

Yavarinasab, A.; Flibotte, S.; Liu, S.; Tropini, C.

10.1101/2022.09.11.507374 — bioengineering — Posted on 2022-09-13

2649 3D in vitro blood-brain-barrier model for investigating barrier insults

Wei, W.; Cardes, F.; Hierlemann, A.; Modena, M. M.

10.1101/2022.09.12.507522 — bioengineering — Posted on 2022-09-13

2650 High Resolution Imaging of the Osteogenic and Angiogenic Interface at the Site of Cranial Bone Defect Repair via Multiphoton Microscopy

Schilling, K.; Zhai, Y.; Zhou, Z.; Zhou, B.; Brown, E.; Zhang, X.

10.1101/2022.09.11.507477 — bioengineering — Posted on 2022-09-13

2651 Modeling bee movement shows how a perceptual masking effect can influence flower discovery, foraging efficiency and pollination

Moran, A.; Lihoreau, M.; Perez-Escudero, A.; Gautrais, J.

10.1101/2022.09.12.507525 — animal behavior and cognition — Posted on 2022-09-13

2652 Max is likely not at the Drosophila histone locus

Xie, M.; Comstra, H. S.; Schmidt, C.; Hodkinson, L.; Rieder, L. E.

10.1101/2022.09.11.507040 — genetics — Posted on 2022-09-13

2653 Evolutionary trajectories are contingent on mitonuclear interactions

Biot-Pelletier, D.; Bettinazzi, S.; Gagnon-Arsenault, I.; Dube, A. K.; Bedard, C.; Nguyen, T. H. M.; Fiumera, H.; Breton, S.; Landry, C.

10.1101/2022.09.11.507487 — evolutionary biology — Posted on 2022-09-13

2654 The Chalcidoidea bush of life - a massive radiation blurred by mutational saturation

Cruaud, A.; Rasplus, J.-Y.; Zhang, J.; Burks, R.; Delvare, G.; Fusu, L.; Gumovsky, A.; Huber, J. T.; Jansta, P.; Mitroiu, M.-D.; Noyes, J. S.; van Noort, S.; Baker, A.; Böhmova, J.; Baur, H.; Blaimer, B. B.; Brady, S. G.; Bubenikova, K.; Chartois, M.; Copeland, R. S.; Dale-Skey Papilloud, N.; Dal Molin, A.; Dominguez, C.; Gebiola, M.; Guerrieri, E.; Kresslein, R. L.; Krogmann, L.; Moriarty Lemmon, E.; Murray, E. A.; Nidelet, S.; Nieves-Aldrey, J. L.; Perry, R. K.; Peters, R. S.; Polaszek, A.; Saune, L.; Torrens, J.; Triapitsyn, S.; Tselikh, E. V.; Yoder, M.; Lemmon, A. R.; Woolley, J. B.; Her

10.1101/2022.09.11.507458 — evolutionary biology — Posted on 2022-09-13

2655 Core species and interactions prominent in fish-associated microbiome dynamics

Yajima, D.; Fujita, H.; Hayashi, I.; Shima, G.; Toju, H.

10.1101/2022.09.11.507499 — ecology — Posted on 2022-09-13

2656 Detecting stabilizing, directional, and disruptive patterns of anthropogenic species loss with general models of nonrandom extinction

Huron, N. A.; Hedges, S. B.; Helmus, M. R.

10.1101/2022.09.11.507476 — ecology — Posted on 2022-09-13

2657 Bull Trout passage at beaver dams in two Montana streams

Wolf, J. M.; Clancy, N. G.; Rosenthal, L. R.

10.1101/2022.09.10.507435 — ecology — Posted on 2022-09-13

2658 Tumor suppressor p53 deficiency increases tumor immunogenicity through promoting IL33-mediated anti-tumor immune responses

Li, Y.; Gao, D. S.; Yi, L.; Gao, F.; Sun, R.; Lu, K. K.; Xu, J.; Shoush, J.; Kykrou, Z.; Liang, M.; Lu, B.

10.1101/2022.09.11.507505 — immunology — Posted on 2022-09-13

2659 The perception of auditory motion in sighted and early blind individuals

Park, W. J.; Fine, I.

10.1101/2022.09.11.507447 — neuroscience — Posted on 2022-09-13

2660 Practical scan-length considerations for mapping upper limb movements to the somatosensory/motor cortex at 7T

Rangaprakash, D.; Rowe, O. E.; Song, H.; Gutierrez-Arango, S.; Fernandez, M. F.; Israel, E. A.; Herr, H. M.; Barry, R. L.

10.1101/2022.09.11.507497 — neuroscience — Posted on 2022-09-13

2661 Subtype-specific roles of ellipsoid body ring neurons in sleep regulation in Drosophila

Yan, W.; Lin, H.; Yu, J.; Wiggin, T. D.; Wu, L.; Meng, Z.; Liu, C.; Griffith, L.

10.1101/2022.09.11.507483 — neuroscience — Posted on 2022-09-13

2662 Two gustatory receptors involved in host plant recognition of silkworm larvae

Endo, H.; Tsuneto, K.; Yamagishi, T.; Dingze, M.; Ito, K.; Nagata, S.; Sato, R.

10.1101/2022.09.12.507514 — neuroscience — Posted on 2022-09-13

2663 Roles of the 5-HT2C receptor on zebrafish sociality

Moura, L. A.; Pyterson, M. P.; Pimentel, A. F. N.; Araujo, F.; de Sousa, L. V. X. B.; Mendes, C. H. M.; Costa, B. P. D.; de Siqueira-Silva, D. H.; Lima-Maximino, M.; Maximino, C.

10.1101/2022.09.12.507567 — neuroscience — Posted on 2022-09-13

2664 Methamphetamine Self-Administration Differential Effects on Mesolimbic Glutathione Levels, Mitochondrial Respiration, and Dopamine Neuron Firing Activity

Dominguez-Lopez, S.; Ahn, B.; Sataranatarajan, K.; Ranjit, R.; Beckstead, M. J.; Van Remmen, H.

10.1101/2022.09.12.507550 — neuroscience — Posted on 2022-09-13

2665 The individual vulnerability to develop compulsive adjunctive behavior is associated with the recruitment of activity-regulated cytoskeleton-associated protein (Arc) within the Locus Coeruleus

Velazquez Sanchez, C.; Muresan, L.; Belin, D.

10.1101/2022.09.13.507749 — neuroscience — Posted on 2022-09-13

2666 Leadership in PhD (LeaP): a longitudinal leadership skill building program for underrepresented biomedical research trainees

Doles, M. D.; Kang, J. Y.; Scholl, L. M.; Doles, J. D.

10.1101/2022.09.11.507461 — scientific communication and education — Posted on 2022-09-13

2667 Loss of FBXO11 function establishes a stem cell program in acute myeloid leukemia through dysregulation of the mitochondrial protease LONP1

10.1101/2022.09.10.507366 — cancer biology — Posted on 2022-09-13

2668 Treatment with anti-HER2 chimeric antigen receptor tumor-infiltrating lymphocytes (CAR-TILs) is safe and associated with antitumor efficacy in mice and companion dogs

Forsberg, E. M.; Riise, R.; Saellstrom, S.; Karlsson, J. W.; Alsen, S.; Bucher, V.; Hemminki, A. E.; Olofsson Bagge, R.; Ny, L.; Nilsson, L. M.; Ronnberg, H.; Nilsson, J. A.

10.1101/2022.09.11.507449 — cancer biology — Posted on 2022-09-13

2669 Fanconi anemia-isogenic head and neck cancer cell line pairs - a basic and translational science resource

Nguyen, H. T.; Tang, W.; Webster, A. L. H.; Whiteaker, J. R.; Chandler, C. M.; Errazquin, R.; Sullivan, L. B.; Jonlin, E.; Hoskins, E. E.; Chen, E. Y.; Fritzke, M.; Paulovich, A. G.; Wells, S. I.; Roohollahi, K.; Dorsman, J.; Brakenhoff, R.; Garcia-Escudero, R.; Smogorzewska, A.; Wakefield, L.; Grompe, M.; Monnat, R. J.

10.1101/2022.09.11.507488 — cancer biology — Posted on 2022-09-13

2670 Phase Transitions in Lipid Bilayers by Biomimetic Photoswitches Based on Cyclocurcumin

Delova, A.; Losantos, R.; Pecourneau, J.; Bernhard, Y.; Mourer, M.; Pasc, A.; Monari, A.

10.1101/2022.09.11.507454 — biophysics — Posted on 2022-09-13

2671 Two-color live-cell STED nanoscopy by click labeling with cell-permeable fluorophores

Gregor, C.; Grimm, F.; Rehman, J.; Wurm, C. A.; Egner, A.

10.1101/2022.09.11.507450 — biophysics — Posted on 2022-09-13

2672 Sequence-based Optimized Chaos Game Representation and Deep Learning for Peptide/Protein Classification

Huang, B.; Zhang, E.; Chaudhari, R.; Gimperlein, H.

10.1101/2022.09.10.507145 — bioinformatics — Posted on 2022-09-13

2673 Ensemble Machine Learning to Boost Ubiquitination-sites Prediction

Mo, X.; Jiang, X.

10.1101/2022.09.11.507485 — bioinformatics — Posted on 2022-09-13

2674 Mining for ions: diagnostic feature detection in MS/MS spectra of post-translationally modified peptides

Geiszler, D. J.; Polasky, D. A.; Yu, F.; Nesvizhskii, A. I.

10.1101/2022.09.12.507594 — bioinformatics — Posted on 2022-09-13

2675 Development of a High-Performance Open-Source 3D Bioprinter

Shiwarksi, D. J.; Tashman, J. W.; Feinberg, A. W.

10.1101/2022.09.11.507416 — bioengineering — Posted on 2022-09-13

2676 Defining Cardiac Recovery at Single Cell Resolution

Amrute, J. M.; Lai, L.; Ma, P.; Koenig, A. L.; Kamimoto, K.; Bredemeyer, A.; Shankar, T. S.; Kuppe, C.; Kadyrov, F. F.; Schulte, L. J.; Stoutenburg, D.; Kopecky, B.; Navankasattusas, S.; Visker, J.; Morris, S. A.; Kramann, R.; Leuschner, F.; Mann, D. L.; Drakos, S. G.; Lavine, K. J.

10.1101/2022.09.11.507463 — genomics — Posted on 2022-09-13

2677 Tropical high-altitude insects show limited capacity to handle high temperatures

Rajpurohit, S.; Solanki, P. S.; Mayekar, H. V.; Arya, H.; Aradhya, R.; Suravajhala, P.; Loeschcke, V.

10.1101/2022.09.10.507406 — evolutionary biology — Posted on 2022-09-13

2678 Drivers of interlineage variability in mitogenomic evolutionary rates in flatworms (Platyhelminthes) are multifactorial

Jakovlic, I.; Zou, H.; Ye, T.; Wang, G.; Li, W.; Zhang, D.

10.1101/2022.09.11.507443 — evolutionary biology — Posted on 2022-09-13

2679 Low precipitation due to climate change consistently reduces multifunctionality of urban grasslands in mesocosms

Rojas-Botero, S.; Teixeira, L. H.; Kollmann, J.

10.1101/2022.09.10.507400 — ecology — Posted on 2022-09-13

2680 Ecological succession revisited from a temporal beta-diversity perspective

Nakadai, R.; Suzuki, S. N.

10.1101/2022.09.11.507494 — ecology — Posted on 2022-09-13

2681 Determination of oligomeric states of proteins via dual-color colocalization with single molecule localization microscopy

Tan, H. L.; Bungert-Plümke, S.; Kortzak, D.; Fahlke, C.; Stölting, G.

10.1101/2021.10.05.463155 — cell biology — Posted on 2022-09-13

2682 Assessing the zoonotic potential of a novel bat morbillivirus

Ikegame, S.; Carmichael, J. C.; Wells, H.; Furler O'Brien, R. L.; Acklin, J. A.; Chiu, H.-P.; Oguntuyo, K. Y.; Cox, R. M.; Patel, A. R.; Kowdle, S.; Stevens, C. S.; Eckley, M.; Zhan, S.; Lim, J. K.; Veit, E. C.; Evans, M.; Hashiguchi, T.; Durigon, E. L.; Schountz, T.; Epstein, J. E.; Plemper, R. K.; Daszak, P.; Anthony, S. J.; Lee, B.

10.1101/2021.09.17.460143 — microbiology — Posted on 2022-09-13

2683 A cryptic transcription factor regulates Caulobacter adhesin development

McLaughlin, M.; Hershey, D. M.; Reyes Ruiz, L. M.; Fiebig, A.; Crosson, S.

10.1101/2022.05.23.493133 — microbiology — Posted on 2022-09-13

2684 Enhancing adoptive T cell therapy with synergistic host immune engagement promotes long-term protection against solid tumors

Adu-Berchie, K.; Brockman, J. M.; Liu, Y.; Zhang, D. K. Y.; Najibi, A. J.; Stafford, A.; Sobral, M. C.; Binenbaum, Y.; Dellacherie, M. O.; Mooney, D. J.

10.1101/2022.09.10.507437 — immunology — Posted on 2022-09-13

2685 Subthreshold serotonin signals combined by the G proteins Gαq and Gαs activate the C. elegans egg-laying muscles

Olson, A. C.; Butt, A. M.; Christie, N. T. M.; Shelar, A.; Koelle, M. R.

10.1101/2022.09.12.507489 — neuroscience — Posted on 2022-09-13

2686 Activity-dependent post-translational regulation of palmitoylating and de-palmitoylating enzymes in the hippocampus

Abazari, D.; Wild, A. R.; Qiu, T.; Dickinson, B. C.; Bamji, S. X.

10.1101/2022.09.12.507668 — neuroscience — Posted on 2022-09-13

2687 Correlated somatosensory input in parvalbumin/pyramidal cells in mouse motor cortex

Goz, R. U.; Hooks, B. M.

10.1101/2022.09.12.507457 — neuroscience — Posted on 2022-09-13

2688 Network controllability measures of subnetworks: implications for neurosciences

Stocker, J. E.; Nozari, E.; van Vugt, M. K.; Jansen, A.; Jamalabadi, H.

10.1101/2022.09.11.507468 — neuroscience — Posted on 2022-09-13

2689 A Programmable Model for Exploring the Functional Logic of the Drosophila Antennal Lobe

Lazar, A. A.; Turkcan, M. K.; Zhou, Y.

10.1101/2022.09.10.506216 — neuroscience — Posted on 2022-09-13

2690 Basolateral amygdala astrocytes are engaged by the acquisition and expression of a contextual fear memory

Ramirez, S.; Suthard, R. L.; Senne, R. A.; Buzharsky, M. D.; Cole, R. H.

10.1101/2022.09.11.507456 — neuroscience — Posted on 2022-09-13

2691 Uncertainty revealed by delayed responses during olfactory matching

Bhowmik, R.; Pardasani, M.; Mahajan, S.; Bhattacharjee, A. S.; Konakamchi, S.; Phadnis, S.; Musthafa, T.; McGowan, E.; Srikanth, P.; Marathe, S. D.; Abraham, N. M.

10.1101/2022.09.11.507462 — neuroscience — Posted on 2022-09-13

2692 Modeling cell size regulation under complex and dynamic environments

Nieto Acuna, C. A.; Vargas-Garcia, C. A.; Singh, A.; Pedraza, J. M.

10.1101/2022.09.09.507356 — systems biology — Posted on 2022-09-13

2693 Root System Architecture and Environmental Flux Analysis in Mature Crops using 3D Root Mesocosms

Dowd, T. G.; Li, M.; Bagnall, G. C.; Johnston, A.; Topp, C. N.

10.1101/2022.09.10.507424 — plant biology — Posted on 2022-09-13

2694 Huntingtin Over-Expression Does Not Alter Overall Survival in Murine Cancer Models

Chan, L.; Hill, A.; Lu, G.; Van Raamsdonk, J.; Gascoyne, R. D.; Hayden, M. R.; Leavitt, B. R.

10.1101/2022.09.11.507440 — cancer biology — Posted on 2022-09-13

2695 Design, synthesis and biological evaluation of novel quercetin derivatives as PPAR-γ partialagonists by modulating Epithelial-mesenchymal transition in lung cancer metastasis

Ballav, S.; Bhosale, M.; Lokhande, K. B.; Paul, M. K.; Padhye, S.; Swami, K. V.; Ranjan, A.; Basu, S.

10.1101/2022.09.11.507444 — cancer biology — Posted on 2022-09-13

2696 The glutathione S-transferase Gstt1 is a robust driver of survival and dissemination in metastases

Ferrer, C. M.; Boon, R.; Cho, H.; Bernasocchi, T.; Wong, L. P.; Cetinbas, M.; Haggerty, E. R.; Mitsiades, I.; Wojtkiewicz, G. R.; McLoughlin, D. E.; Rheinbay, E.; Sadreyev, R.; Juric, D.; Mostoslavsky, R.

10.1101/2022.09.10.507413 — cancer biology — Posted on 2022-09-13

2697 Comprehensive Analysis of Regenerative and Transformed Liver Reveals Distinct, Early Metabolic Alterations in Cancer

McLaughlin, D.; Mir, H.; Nam, M.; Possemato, R.

10.1101/2022.09.10.507425 — cancer biology — Posted on 2022-09-13

2698 E-cigarette aerosol exposure of pulmonary surfactant impairs its surface tension reducing function

Graham, E.; McCaig, L.; Shui-Kei Lau, G.; Tejura, A.; Cao, A.; Zuo, Y. Y.; Veldhuizen, R.

10.1101/2022.08.16.501319 — biophysics — Posted on 2022-09-13

2699 HiC4D: Forecasting spatiotemporal Hi-C data with residual ConvLSTM

Liu, T.; Wang, Z.

10.1101/2022.09.10.507434 — bioinformatics — Posted on 2022-09-13

2700 Bioprinting in granular support hydrogels - characterizing the role of particle morphology and packing density

Britchfield, G.; Daly, A.

10.1101/2022.09.10.507420 — bioengineering — Posted on 2022-09-13

2701 Mitochondrial effects on fertility and longevity in Tigriopus californicus contradict predictions of the mother's curse hypothesis

Watson, E. T.; Flanagan, B. A.; Pascar, J. A.; Edmands, S.

10.1101/2022.04.20.488069 — evolutionary biology — Posted on 2022-09-13

2702 The influence of the social environment on larval development and resulting caste in Bombus impatiens

Barie, K.; Amsalem, E.

10.1101/2022.09.09.507355 — ecology — Posted on 2022-09-13

2703 Transcriptional profiles of functionally distinct HLADR+CD38+ CD8 T cells subsets from acute febrile dengue patients

Singh, P.; Bajpai, P.; Maheshwari, D.; Chawla, Y. M.; Gottimukkala, K.; Reddy, E. S.; Saini, K.; Nayak, K.; Gunisetty, S.; Aggarwal, C.; Jain, S.; Verma, C.; Jain, P.; Soneja, M.; Wig, N.; Murali-Krishna, K.; Chandele, A.

10.1101/2022.09.09.507387 — immunology — Posted on 2022-09-13

2704 In vivo Safety and Immunoactivity of Oncolytic Jurona Virus in Hepatocellular Carcinoma: A Comprehensive Proteogenomic Analysis

Zhang, Y.; Tesfay, M.; Ferdous, K. U.; Taylor, M.; Gabere, M. N.; Simoes, C. C.; Dumbauld, C.; Barro, O.; Graham, A.; Washam, C. L.; Alkam, D.; Gies, A.; Chamcheu, J. C.; Byrum, S. D.; Post, S. R.; Kelly, T.; Borad, M.; Cannon, M. J.; Basnakian, A.; Nagalo, B. M.

10.1101/2022.09.09.507330 — immunology — Posted on 2022-09-13

2705 Effects of vestibular stimulation on gait stability when walking at different step widths

Magnani, R. M.; van Dieen, J. H.; Bruijn, S. M.

10.1101/2021.09.09.459650 — neuroscience — Posted on 2022-09-13

2706 Increased conductance associated with higher photosynthesis in leaves and green stems of avocado exposed to diffuse light

Berry, Z. C.; Avila-Lovera, E.; Ellertson, K.; Goldsmith, G. R.

10.1101/2022.09.09.507344 — physiology — Posted on 2022-09-13

2707 DLL3 REGULATES NOTCH SIGNALING IN SCLC

Kim, J. W.; Ko, J. H.; Sage, J.

10.1101/2022.07.08.499386 — cancer biology — Posted on 2022-09-13

2708 Meiotic drive does not impede success in sperm competition in the stalk-eyed fly, Teleopsis dalmanni

Bates, S.; Meade, L. C.; Pomiankowski, A.

10.1101/2022.09.09.507334 — evolutionary biology — Posted on 2022-09-13

2709 Dating the origin and spread of specialization on human hosts in Aedes aegypti mosquitoes

Rose, N. H.; Badolo, A.; Sylla, M.; Akorli, J.; Otoo, S.; Gloria-Soria, A.; Powell, J. R.; White, B. J.; Crawford, J. E.; McBride, C. S.

10.1101/2022.09.09.507331 — evolutionary biology — Posted on 2022-09-13

2710 Differential gene expression and mitonuclear incompatibilities in fast- and slow-developing inter-population Tigriopus californicus hybrids

Healy, T. M.; Burton, R. S.

10.1101/2022.09.09.507197 — evolutionary biology — Posted on 2022-09-13

2711 Fruit phosphorus concentration does not affect oviposition preference in the invasive pest Drosophila suzukii

Olazcuaga, L.; Guilhot, R.; Claret, J.-L.; Rode, N. O.

10.1101/2022.09.09.507340 — ecology — Posted on 2022-09-13

2712 Body mass change over winter is consistently sex-specific across roe deer populations

Hewison, A. J. M.; Bonnot, N.; Gaillard, J.-M.; Kjellander, P.; Lemaitre, J.-F.; Morellet, N.; Pellerin, M.

10.1101/2022.09.09.507329 — ecology — Posted on 2022-09-13

2713 Effects of ancient anthropogenic clam gardens on the growth, survival, and transcriptome of Pacific littleneck clams (Leukoma staminea)

Raap, M. R.; Gurney-Smith, H. J.; Dudas, S. E.; Pearce, C. M.; Leong, J. S.; Sutherland, B. J. G.; Koop, B. F.

10.1101/2022.09.09.507365 — ecology — Posted on 2022-09-13

2714 Membrane potential dynamics of excitatory and inhibitory neurons in mouse barrel cortex during active whisker sensing

Kiritani, T.; Pala, A.; Gasselin, C.; Crochet, S.; Petersen, C. C.

10.1101/2022.09.12.507622 — neuroscience — Posted on 2022-09-13

2715 Geometry of spiking patterns in early visual cortex: a Topological Data Analytic approach

Guidolin, A.; Desroches, M.; Victor, J. D.; Purpura, K. P.; Rodrigues, S.

10.1101/2022.03.16.484568 — neuroscience — Posted on 2022-09-13

2716 Cholecystokinin-expressing (CCK+) basket cells are key controllers of theta-gamma coupled rhythms in the hippocampus

Chatzikalymniou, A.; Sengupta, S.; Lefebvre, J.; Skinner, F.

10.1101/2022.06.01.494440 — neuroscience — Posted on 2022-09-13

2717 Denoising physiological data collected during multi-band, multi-echo EPI sequences

Bottenhorn, K. L.; Salo, T.; Riedel, M. C.; Sutherland, M. T.; Robinson, J. L.; Musser, E. D.; Laird, A. R.

10.1101/2021.04.01.437293 — physiology — Posted on 2022-09-13

2718 A community-science approach identifies genetic variants associated with three color morphs in ball pythons (Python regius)

Brown, A. R.; Comai, K.; Mannino, D.; McCullough, H.; Meyers, H. C.; Donekal, Y.; The BIO306 Consortium, ; Graves, C. W.; Seidel, H. S.

10.1101/2021.05.19.444867 — genetics — Posted on 2022-09-13

2719 Redefining hypo- and hyper-responding phenotypes of CFTR mutants for understanding and therapy.

Hillenaar, T.; Beekman, J.; van der Sluijs, P.; Braakman, I.

10.1101/2022.09.12.507537 — biochemistry — Posted on 2022-09-13

2720 Positive effects of tree diversity on tropical forest restoration in a field-scale experiment

Veryard, R.; Wu, J.; O'Brien, M. J.; Anthony, R.; Both, S.; Burslem, D. F. R. P.; Chen, B.; Fernandez-Miranda Cagigal, E.; Godfray, H. C. J.; Godoong, E.; Liang, S.; Saner, P.; Schmid, B.; Sau Wai, Y.; Xie, J.; Reynolds, G.; Hector, A.

10.1101/2022.09.09.507141 — ecology — Posted on 2022-09-13

2721 Redox regulation of Kv7 channels through EF3 hand of calmodulin

Nunez, E.; Jones, F.; Muguruza-Montero, A.; Urrutia, J.; Aguado, A.; Malo, C.; Domene, C.; Bernardo-Seisdedos, G.; Millet, O.; Gamper, N.; Villarroel, A.

10.1101/2022.09.11.507486 — cell biology — Posted on 2022-09-13

2722 Comparing the representation of a simple visual stimulus across the cerebellar network

Petrucco, L.; Prat, O.; Portugues, R.; Stih, V.

10.1101/2022.09.12.507660 — neuroscience — Posted on 2022-09-13

2723 GPU-Accelerated All-atom Particle-Mesh Ewald Continuous Constant pH Molecular Dynamics in Amber

Harris, J. A.; Liu, R.; Martins de Oliveira, V.; Vazquez Montelongo, E.; Henderson, J. A.; Shen, J.

10.1101/2022.06.04.494833 — biophysics — Posted on 2022-09-13

2724 Modeling effects of inter-group contact on links between population size and cultural complexity

Ben-Oren, Y.; Strassberg, S. S.; Hovers, E.; Kolodny, O.; Creanza, N.

10.1101/2022.09.11.507470 — evolutionary biology — Posted on 2022-09-13

2725 A Corollary Discharge Circuit in Human Speech

Khalilian-Gourtani, A.; Wang, R.; Chen, X.; Yu, L.; Dugan, P.; Friedman, D.; Doyle, W.; Devinsky, O.; Wang, Y.; Flinker, A.

10.1101/2022.09.12.507590 — neuroscience — Posted on 2022-09-13

2726 Selective attention reduces responses to relevant sounds in human auditory cortex

Castellanos, A. L.; De Martino, F.; Ghose, G. M.; Gulban, O. F.; Moerel, M.

10.1101/2022.09.12.507664 — neuroscience — Posted on 2022-09-13

2727 Rhythmic Modulation of Visual Discrimination is Dependent on Individuals' Spontaneous Motor Tempo

Snapiri, L.; Kaplan, Y.; Shalev, N.; Landau, A. N.

10.1101/2022.09.10.506584 — neuroscience — Posted on 2022-09-13

2728 Haloperidol-induced immediate early genes in striatopallidal neurons requires the converging activation of cAMP/PKA/DARPP-32 and mTOR pathways

Onimus, O.; Valjent, E.; Fisone, G.; Gangarossa, G.

10.1101/2022.09.10.507436 — neuroscience — Posted on 2022-09-13

2729 Emergence of syntax and word prediction in an artificial neural circuit of the cerebellum

Ohmae, K.; Ohmae, S.

10.1101/2022.09.11.507501 — neuroscience — Posted on 2022-09-13

2730 Blockade of ghrelin receptor signaling enhances conditioned passive avoidance and context-associated neural circuit activation in fasted male rats

Edwards, C. M.; Guerrero, I. E.; Dolezel, T.; Zheng, H.; Rinaman, L.

10.1101/2022.02.11.480168 — neuroscience — Posted on 2022-09-13

2731 Non-necessary neural activity in the primate cortex

Tremblay, S.; Testard, C.; Inchauspe, J.; Petrides, M.

10.1101/2022.09.12.506984 — neuroscience — Posted on 2022-09-13

2732 Cross-Modal Representation of Identity in Primate Hippocampus

Tyree, T.; Metke, M.; Miller, C.

10.1101/2022.09.12.507611 — neuroscience — Posted on 2022-09-13

2733 Hourglass, a tool to mine bioimaging data, uncovers sex-disparities in the IL-6-associated T cell response in pancreatic tumors

Aliar, K.; Waterhouse, H. R.; Vyas, F.; Krebs, N.; Poulton, E.; Zhang, B.; Chan, N.; Bronsert, P.; Fischer, S. E.; Gallinger, S.; Grünwald, B. T.; Khokha, R.

10.1101/2022.09.12.507618 — cancer biology — Posted on 2022-09-13

2734 Genome-wide association studies of polygenic risk score-derived phenotypes may lead to inflated false positive rates

Uffelmann, E.; Posthuma, D.; Peyrot, W. J.

10.1101/2022.09.10.507410 — bioinformatics — Posted on 2022-09-13

2735 Impact of storage on starch digestibility and texture of a high-amylose wheat bread

Corrado, M.; Zafeiriou, P.; Ahn-Jarvis, J. H.; Savva, G. M.; Edwards, C. H.; Hazard, B. A.

10.1101/2022.07.04.498686 — biochemistry — Posted on 2022-09-13

2736 The mediodorsal thalamus supports adaptive responding based on stimulus-outcome associations

Morceau, S.; Faugere, A.; Coutureau, E.; Wolff, M.

10.1101/2022.09.12.507585 — animal behavior and cognition — Posted on 2022-09-13

2737 Phenotypic plasticity and the anthropause: an urban bird becomes less aggressive

Walters, M.; Diamant, E. S.; Wong, F.; Cen, C.; Yeh, P.

10.1101/2022.09.12.507677 — animal behavior and cognition — Posted on 2022-09-13

2738 Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation

Landshammer, A.; Bolondi, A.; Kretzmer, H.; Much, C.; Buschow, R.; Rose, A.; Wu, H.-J.; Mackowiak, S.; Braendl, B.; Giesselmann, P.; Tornisiello, R.; Parsi, K. M.; Huey, J.; Mielke, T.; Meierhofer, D.; Maehr, R.; Hnisz, D.; Michor, F.; Rinn, J. L.; Meissner, A.

10.1101/2022.09.12.507139 — genomics — Posted on 2022-09-13

2739 Unified establishment and epigenetic inheritance of DNA methylation through cooperative MET1 activity

Briffa, A.; Hollwey, E.; Shahzad, Z.; Moore, J. D.; Lyons, D. B.; Howard, M.; Zilberman, D.

10.1101/2022.09.12.507517 — genetics — Posted on 2022-09-13

2740 Global phylogenomic assessment of Leptoseris and Agaricia reveals substantial undescribed diversity at mesophotic depths

10.1101/2022.09.12.504660 — evolutionary biology — Posted on 2022-09-13

2741 An ultra high-throughput, massively multiplexable, single-cell RNA-seq platform in yeasts

Brettner, L. M.; Eder, R.; Schmidlin, K.; Geiler-Samerotte, K.

10.1101/2022.09.12.507686 — molecular biology — Posted on 2022-09-13

2742 Virucidal Activity of Potassium Hydroxide Modeling on Tospovirus

Zumrutdal, E.; Kamberoglu, M. A.; Saglam, H. N.

10.1101/2022.09.12.507442 — microbiology — Posted on 2022-09-13

2743 Multi-omics analysis of mouse fecal microbiome reveals supplier-dependent functional differences and novel metagenome-assembled genomes

McAdams, Z. L.; Busi, S. B.; Gustafson, K. L.; Bivens, N.; Franklin, C. L.; Wilmes, P.; Ericsson, A. C.

10.1101/2022.09.12.507288 — microbiology — Posted on 2022-09-13

2744 Using Watershed Characteristics for Improving Fecal Source Identification

Hart, J. J.; Jamison, M. N.; McNair, J. N.; Woznicki, S. A.; Jordan, B.; Rediske, R. R.

10.1101/2022.06.16.496426 — microbiology — Posted on 2022-09-13

2745 Collective protection against the type VI secretion system in bacteria

Granato, E. T.; Smith, W. P. J.; Foster, K. R.

10.1101/2022.09.12.507624 — microbiology — Posted on 2022-09-13

2746 Immunological landscape of human lymph nodes during ex vivo measles virus infection

Acklin, J. A.; Patel, A. R.; Horiuchi, S.; Moss, A. S.; Kurland, A. P.; Thibault, P.; Degrace, E. J.; Ikegame, S.; Carmichael, J.; Imai, N.; Ueno, H.; Tweel, B.; Johnson, J. R.; Rosenberg, B. R.; Lee, B.; Lim, J. K.

10.1101/2022.09.12.507535 — immunology — Posted on 2022-09-13

2747 Nonlinear EEG signatures of mind wandering during breath focus meditation

Lu, Y.; Rodriguez-Larios, J.

10.1101/2022.03.27.485924 — neuroscience — Posted on 2022-09-13

2748 Microbial glutamate metabolism predicts intravenous cocaine self-administration in Diversity Outbred mice

Tran, T. D. B.; Nguyen, H.; Sodergren, E.; Center for Systems Neurogenetics of Addiction, ; Dickson, P. E.; Wright, S.; Philip, V. M.; Weinstock, G. M.; Chesler, E. A.; Zhou, Y.; Bubier, J. A.

10.1101/2022.09.11.507297 — neuroscience — Posted on 2022-09-13

2749 Weight Perturbation Learning Performs Similarly or Better than Node Perturbation on Broad Classes of Temporally Extended Tasks

Züge, P.; Klos, C.; Memmesheimer, R.-M.

10.1101/2021.10.04.463055 — neuroscience — Posted on 2022-09-13

2750 Decoding of the ubiquitin code for clearance of colliding ribosomes by the RQT complex

Matsuo, Y.; Inada, T.

10.1101/2022.09.12.507701 — biochemistry — Posted on 2022-09-13

2751 Exploration of O-GlcNAc-transferase (OGT) glycosylation sites reveals a target sequence compositional bias

Chong, P. A.; Nosella, M. L.; Vanama, M.; Ruiz-Arduengo, R.; Forman-Kay, J. D.

10.1101/2022.09.12.507593 — biochemistry — Posted on 2022-09-13

2752 Kinetic and Structural Analysis of Ribonucleotide Extension by DNA Polymerase η

Chang, C.; Lee Luo, C.; Eleraky, S.; Lin, A.; Zhou, G.; Gao, Y.

10.1101/2022.09.12.507597 — biochemistry — Posted on 2022-09-13

2753 Optimizing data points per protein increases protein identifications while maintaining quantitative precision in short gradient data-independent acquisition proteomics

Doellinger, J.; Blumenscheit, C.; Schneider, A.; Lasch, P.

10.1101/2022.09.12.507556 — biochemistry — Posted on 2022-09-13

2754 A high-throughput exonuclease assay based on the fluorescent base analog 2-aminopurine

Botto, M.; Murthy, S.; Lamers, M.

10.1101/2022.09.12.507544 — biochemistry — Posted on 2022-09-13

2755 A new route for integron cassette dissemination among bacterial genomes

Loot, C.; Millot, G.; Richard, E.; Darracq, B.; Vit, C.; Parissi, V.; Lemoine, F.; Niault, T.; Cury, J.; Rocha, E. P.; Mazel, D.

10.1101/2022.09.11.507474 — genetics — Posted on 2022-09-13

2756 In silico labeling enables kinetic myelination assay in brightfield

Fang, J.; Bergsdorf, E. Y.; Unterreiner, V.; La Greca, A.; Dergai, O.; Claerr, I.; Luong-Nguyen, N.-H.; Galuba, I.; Moutsatsos, I.; Hatakeyama, S.; Groot-Kormelink, P.; Zeng, F.; Zhang, X.

10.1101/2022.09.11.507500 — cell biology — Posted on 2022-09-13

2757 Miniaturised structured illumination microscopy using two 3-axis MEMS micromirrors

Tinning, P. W.; Donnachie, M.; Christopher, J.; Uttamchandani, D.; Bauer, R.

10.1101/2022.09.12.507543 — cell biology — Posted on 2022-09-13

2758 Using machine learning to predict protein-protein interactions between a zombie ant fungus and its carpenter ant host

Will, I.; Beckerson, W. C.; de Bekker, C.

10.1101/2022.09.09.507359 — molecular biology — Posted on 2022-09-13

2759 The ribosome quality control factors Asc1 and Hel2 regulate the expression of HSP70 during heat shock and recovery

Boopathy, L. R. A.; Beadle, E.; Xiao, A.; Rico, A. G.-B.; Alecki, C.; Garcia de Andres, I.; Vera, M.

10.1101/2022.09.12.507689 — molecular biology — Posted on 2022-09-13

2760 The dynamic response of quorum-sensing to density is robust to signal supplementation and signal synthase knockouts

Rattray, J. B.; Kramer, P.; Gurney, J.; Thomas, S. A.; Brown, S. P.

10.1101/2022.09.12.507654 — microbiology — Posted on 2022-09-13

2761 A scalable, Rotating Disc Bioelectrochemical Reactor (RDBER) suitable for the cultivation of both cathodic and anodic biofilms

Hackbarth, M.; Gescher, J.; Horn, H.; Reiner, J. E.

10.1101/2022.09.12.507646 — microbiology — Posted on 2022-09-13

2762 Interspecies transmission from pigs to ferrets of antigenically distinct swine H1 influenza A viruses with loss in reactivity to human vaccine virus antisera as measures of relative zoonotic risk

Kimble, J. B.; Souza, C. K.; Anderson, T. K.; Arendsee, Z. W.; Hufnagel, D. E.; Young, K. M.; Lewis, N. S.; Davis, C. T.; Vincent Baker, A. L.

10.1101/2022.09.12.507661 — microbiology — Posted on 2022-09-13

2763 Discovery of a novel monoclonal PD-L1 antibody H1A that promotes T-cell mediated tumor killing activity in renal cell carcinoma

An, Z.; Gicobi, J. K.; Harrington, S. M.; Zhang, H.; Xu, T.; Hirdler, J. B.; Lohse, C.; Leibovich, B. C.; Dong, H.; Lucien, F.

10.1101/2022.09.10.507426 — immunology — Posted on 2022-09-13

2764 Transiently heritable fates and quorum sensing drive early IFN-I response dynamics

Van Eyndhoven, L. C.; Verberne, V. P. G.; Bouten, C. V. C.; Singh, A.; Tel, J.

10.1101/2022.09.11.507479 — immunology — Posted on 2022-09-13

2765 Spectral brain signatures of aesthetic natural perception in the alpha and beta frequency bands

Kaiser, D.

10.1101/2022.08.11.503584 — neuroscience — Posted on 2022-09-13

2766 Regulation of oligodendrocyte lineage development by VAMP2/3 in the developing mouse spinal cord

Fekete, C. D.; Horning, R. Z.; Doron, M. S.; Nishiyama, A.

10.1101/2022.09.10.507429 — neuroscience — Posted on 2022-09-13

2767 Annotation of Spatially Resolved Single-cell Data with STELLAR

Brbic, M.; Cao, K.; Hickey, J. W.; Tan, Y.; Snyder, M.; Nolan, G. P.; Leskovec, J.

10.1101/2021.11.24.469947 — bioinformatics — Posted on 2022-09-13

2768 Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub

Wilkinson, M.; Wilkinson, O. J.; Feyerherm, C.; Fletcher, E. E.; Wigley, D. B.; Dillingham, M. S.

10.1101/2022.09.12.506733 — biochemistry — Posted on 2022-09-12

2769 Limitations of qPCR to estimate DNA quantity: AnRFU method to facilitate inter-laboratory comparisonsfor activity level, and general applicability

Gill, P.; Bleka, O.; Fonnelop, A. E.

10.1101/2022.05.23.493102 — biochemistry — Posted on 2022-09-13

2770 slendr: a framework for spatio-temporal population genomic simulations on geographic landscapes

Petr, M.; Haller, B. C.; Ralph, P. L.; Racimo, F.

10.1101/2022.03.20.485041 — genomics — Posted on 2022-09-12

2771 A Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1-mediated Trabeculation Cessation

Conlon, F.; Shi, W.; Scialdone, A. P.; Emerson, J. I.; Mei, L.; Wasson, L. K.; Davies, H. A.; Seidman, C. E.; Seidman, J. G.; Cook, J.

10.1101/2022.09.12.507607 — developmental biology — Posted on 2022-09-12

2772 Stimulation-responsive enhancers regulate inflammatory gene activation through retention and modification of H2A.Z-variant accessible nucleosomes

Sporrij, A.; Prasad, M.; Muhire, B.; Fast, E. M.; Manning, M. E.; Choudhuri, A.; Weiss, J.; Koh, M.; Yang, S.; Kingston, R. E.; Tolstorukov, M.; Clevers, H.; Zon, L. I.

10.1101/2022.09.12.507565 — developmental biology — Posted on 2022-09-13

2773 Drosophila Males Use 5'-to-3' Phased Biogenesis to Make Stellate-silencing piRNAs that Lack Homology to Maternally Deposited piRNA Guides

Venkei, Z. G.; Gainetdinov, I.; Starostik, M.; Choi, C.; Chen, P.; Balsara, C.; Whitfield, T.; Bell, G. W.; Feng, S.; Jacobsen, S. E.; Aravin, A.; Kim, J. K.; Zamore, P.; Yamashita, Y. M.

10.1101/2022.09.12.507655 — developmental biology — Posted on 2022-09-13

2774 Balanced SET levels favor the correct enhancer repertoire during cell fate acquisition

Mattia, Z.; Banfi, F.; Massimino, L.; Volpin, M.; Bellini, E.; Brusco, S.; Merelli, I.; Barone, C.; Bruni, M.; Bossini, L.; Lamparelli, L. A.; Pintado, L.; Spinelli, S.; Mologni, L.; Colasante, G.; Ungaro, F.; Cioni, J.-M.; Azzoni, E.; Piazza, R.; Montini, E.; Broccoli, V.; Sessa, A.

10.1101/2022.09.12.507599 — developmental biology — Posted on 2022-09-13

2775 ARHGAP18-Ezrin functions as a RhoA autoregulatory module in the organization of apical microvilli

Lombardo, A. T.; Mitchell, C. A. R.; Zaman, R.; McDermitt, D. J.; Bretscher, A.

10.1101/2022.09.12.507663 — cell biology — Posted on 2022-09-12

2776 A phase-separated biomolecular condensate nucleates polymerization of the tubulin homolog FtsZ to spatiotemporally regulate bacterial cell division

Ramm, B.; Schumacher, D.; Harms, A.; Heermann, T.; Klos, P.; Mueller, F.; Schwille, P.; Sogaard-Andersen, L.

10.1101/2022.09.12.507586 — cell biology — Posted on 2022-09-12

2777 Phosphorylation of Gαi shapes canonical Gα(i)βγ/GPCR signaling

Roy, S.; Silas, A. J.; Ghassemian, M.; Kufareva, I.; Ghosh, P.

10.1101/2022.09.11.507491 — cell biology — Posted on 2022-09-12

2778 Camel urine limits proliferation and modifies cell morphology in human renal tumoral and non-tumoral cells

Iglesias Pastrana, C.; Sgobba, M. N.; Navas Gonzalez, F. J.; Delgado Bermejo, J. V.; Duarte, I. F.; Lentini, G.; Kamal Sayed Osman, T.; Guerra, L.; Ciani, E.

10.1101/2022.09.12.507088 — cell biology — Posted on 2022-09-13

2779 Identification of a novel family of benzimidazole species-selective Complex I inhibitors as potential anthelmintics

Davie, T. W.; Serrat, X.; Snider, J.; Stagljar, I.; Hirano, H.; Watanabe, N.; Osada, H.; Fraser, A. G.

10.1101/2022.09.12.507634 — molecular biology — Posted on 2022-09-13

2780 Alternatively Spliced Landscape of PPARγ mRNA in Podocytes is Distinct from Adipose Tissue

Bryant, C.; Webb, A.; Banks, A. S.; Chandler, D.; Govindarajan, R.; Agrawal, S.

10.1101/2022.09.12.507605 — molecular biology — Posted on 2022-09-13

2781 Prevalence and public health significance of Lyssavirus in bats in North region of Cameroon

Dah, I.; Namegni, R. S. P.; Mouiche, M. M. M.; Dickmu, S. J.; Nguena, R. G. N.; Conclois, I.; Florian, L.; God-Yang, L.; Feussom, J. M. K.; Wade, A.; Misse, D.; Awah-Ndukum, J.

10.1101/2022.09.12.507528 — microbiology — Posted on 2022-09-12

2782 Molecular analysis of the interactions between phages and the bacterial host Klebsiella pneumoniae

Bleriot, I.; Blasco, L.; Pacios, O.; Fernandez-Garcia, L.; Lopez, M.; Ortiz-Cartagena, C.; Barrio-Pujante, A.; Fernandez-Cuenca, F.; Pascual, A.; Martinez-Martinez, L.; Oteo-Iglesias, J.; Tomas, M.

10.1101/2022.09.12.507515 — microbiology — Posted on 2022-09-13

2783 Brightness illusions evoke pupil constriction and a preceding primary visual cortex response in rats

Vasilev, D.; Raposo, I.; Totah, N. K.

10.1101/2022.07.13.499566 — neuroscience — Posted on 2022-09-12

2784 Structural basis for mTORC1-dependent regulation of the lysosomal and autophagic transcription factor TFEB

Cui, Z.; Napolitano, G.; de Araujo, M. E. G.; Esposito, A.; Monfregola, J.; Huber, L.; Ballabio, A.; Hurley, J. H.

10.1101/2022.09.12.507619 — cell biology — Posted on 2022-09-12

2785 Optimized fluorescent proteins for 4-color and photoconvertible live-cell imaging in Neurospora crassa

Wang, Z.; Bartholomai, B. M.; Loros, J. J.; Dunlap, J. C.

10.1101/2022.09.12.507692 — cell biology — Posted on 2022-09-12

2786 Cell adhesion and spreading on fluid membranes through microtubules-dependent mechanotransduction

Mikhajlov, O.; Adar, R. M.; Tatulea-Codrean, M.; Mace, A.-S.; Manzi, J.; Tabarin, F.; Battistella, A.; Di Federico, F.; Joanny, J.-F.; Tran van Nhieu, G.; Bassereau, P.

10.1101/2022.09.12.507658 — cell biology — Posted on 2022-09-12

2787 A systematic, cell-based comparison of G-protein binding domains for their potential as localization-based, genetically encoded biosensors of Cdc42 or Rac activity

Mahlandt, E. K.; Chertkova, A. O.; Goedhart, J.

10.1101/2022.09.12.507573 — cell biology — Posted on 2022-09-12

2788 Mountains as refugia: evidence from bumble bee brain transcriptomes

Fisher, K.; Duennes, M. A.; Woodard, S. H.

10.1101/2022.09.09.507046 — ecology — Posted on 2022-09-12

2789 Temperature and dietary energy content influence female maturation age and egg nutritional content in Atlantic salmon

Maamela, K. S.; Asheim, E. R.; Debes, P. V.; House, A. H.; Erkinaro, J.; Liljeström, P.; Primmer, C. R.; Mobley, K. B.

10.1101/2022.09.09.507230 — ecology — Posted on 2022-09-12

2790 Novel 'GaEl antigenic patches' identified by 'reverse epitomics' approach to design multi-patch vaccines against NIPAH infection, a silent threat to global human health

Srivastava, S.; Kolbe, M.

10.1101/2022.09.09.507124 — immunology — Posted on 2022-09-12

2791 Cold exposure induces dynamic changes in circulating triacylglycerol species, which is dependent on intracellular lipolysis: a randomized cross-over trial

Straat, M.; Jurado Fasoli, L.; Ying, Z.; Nahon, K. J.; Janssen, L.; Boon, M.; Grabner, G.; Kooijman, S.; Zimmermann, R.; Giera, M.; Rensen, P. C.; Martinez, B.

10.1101/2022.09.09.507312 — physiology — Posted on 2022-09-12

2792 Modeling Global Genomic Instability in Chronic Myeloid Leukemia (CML) using patient-derived induced pluripotent stem cells (iPSC)

Telliam, G.; Desterke, C.; Imeri, J.; Mkacher, R.; Oudrhiri, N.; Balducci, E.; Arnoux, M.; Acloque, H.; Bennaceur-Griscelli, A.; Turhan, A. G.

10.1101/2022.09.09.505857 — cancer biology — Posted on 2022-09-12

2793 Effects of heavy water on protein dynamics studied by molecular dynamics simulation: Focusing on dynamical parameters obtained by quasi-elastic neutron scattering

Matsuo, T.

10.1101/2022.09.08.507213 — biophysics — Posted on 2022-09-12

2794 Orientation-locked DNA origami for stable trapping of small proteins in the NEOtrap

Wen, C.; Bertosin, E.; Shi, X.; Dekker, C.; Schmid, S.

10.1101/2022.09.09.507286 — biophysics — Posted on 2022-09-12

2795 Mistle: bringing spectral library predictions to metaproteomics with an efficient search index

Nowatzky, Y.; Benner, P.; Reinert, K.; Muth, T.

10.1101/2022.09.09.507252 — bioinformatics — Posted on 2022-09-12

2796 DrTransformer: Heuristic cotranscriptional RNA folding using the nearest neighbor energy model

Badelt, S.; Lorenz, R.; Hofacker, I.

10.1101/2022.09.08.507181 — bioinformatics — Posted on 2022-09-12

2797 An Immune Cell Recirculation-Enabled Microfluidic Array to Study Dynamic Immunotherapeutic Activity in Recapitulated Tumor Microenvironment

Chi, C.-W.; Lao, Y.-H.; Ahmed, A. H. R.; He, S.; Merghoub, T.; Leong, K. W.; Wang, S.

10.1101/2022.09.09.507299 — bioengineering — Posted on 2022-09-12

2798 Coarse-scale Optoretinography(CoORG) with extended field-of-view for normative characterization.

Jiang, X.; Liu, T.; Pandiyan, V. P.; Slezak, E.; Sabesan, R.

10.1101/2022.09.08.507165 — bioengineering — Posted on 2022-09-12

2799 Integrating gene annotation with orthology inference at scale

Kirilenko, B. M.; Munegowda, C.; Osipova, E.; Jebb, D.; Sharma, V.; Blumer, M.; Morales, A.; Ahmed, A.-W.; Kontopoulos, D.-G.; Hilgers, L.; Zoonomia Consortium, ; Hiller, M.

10.1101/2022.09.08.507143 — genomics — Posted on 2022-09-12

2800 Probabilisitic Matrix Factorization for Gene Regulatory Network Inference

Mahmood, O.; Skok Gibbs, C.; Bonneau, R.; Cho, K.

10.1101/2022.09.09.507305 — genomics — Posted on 2022-09-12

2801 Crosstalk between RNA m6A and DNA methylation regulates transposable element chromatin activation and cell fate in human pluripotent stem cells

Sun, T.; Xu, Y.; Xiang, Y.; Soderblom, E. J.; Diao, Y.

10.1101/2022.09.08.507172 — genetics — Posted on 2022-09-12

2802 FUNCTIONAL EXTINCTION OF A GENUS OF CANOPY-FORMING MACROALGAE (CYSTOPHORA SPP.) ACROSS ITS WARM RANGE EDGE

Pessarrodona, A.

10.1101/2022.09.08.507225 — ecology — Posted on 2022-09-12

2803 Multiscale assessment of oviposition habitat associations and implications for management in the spotted lanternfly (Lycorma delicatula), an emerging invasive pest

Ramirez, V. A.; De Bona, S.; Helmus, M. R.; Behm, J. E.

10.1101/2022.09.08.507131 — ecology — Posted on 2022-09-12

2804 Low human health risks of algal toxins from consuming fish caught in Lake St. Clair

Shahmohamadloo, R. S.; Bhavsar, S. P.; Ortiz Almirall, X.; Marklevitz, S. A.; Rudman, S. M.; Sibley, P. K.

10.1101/2022.09.08.507173 — ecology — Posted on 2022-09-12

2805 Mapping global land sharing-sparing patterns between human and wildlife

Zhang, C.; Wang, Y.; Pan, S.; Yang, B.; Zhan, X.; Chang, J.; Li, J.; Dai, Q.

10.1101/2022.09.09.507273 — ecology — Posted on 2022-09-12

2806 Perceptual learning improves discrimination while distorting appearance

Szpiro, S. F. A.; Burlingham, C. S.; Simoncelli, E. P.; Carrasco, M.

10.1101/2022.09.08.507104 — neuroscience — Posted on 2022-09-12

2807 Effect of paclitaxel treatment on cellular mechanics and morphology of human oesophageal squamous cell carcinoma in 2D and 3D environments

Kiwanuka, M.; Higgins, G.; Ngcobo, S.; Nagawa, J.; Lang, D. M.; Zaman, M. H.; Davies, N. H.; Franz, T.

10.1101/2022.03.06.483167 — cancer biology — Posted on 2022-09-12

2808 Aspirin reprogrammes colorectal cancer cell metabolism and sensitises to glutaminase inhibition

Holt, A. K.; Najumudeen, A. K.; Hoskin, A. J.; Legge, D. N.; Mortensson, E. M. H.; Flanagan, D. J.; Jones, N.; Kollareddy, M.; Collard, T. J.; Timms, P.; Sansom, O. J.; Williams, A. C.; Vincent, E. E.

10.1101/2022.08.24.505115 — cancer biology — Posted on 2022-09-12

2809 Fluorescence Lifetime: Beating the IRF and interpulse window

Fazel, M.; Vallmitjana, A.; Scipioni, L.; Gratton, E.; Digman, M. A.; Presse, S.

10.1101/2022.09.08.507224 — biophysics — Posted on 2022-09-12

2810 Literature-based predictions of treatments for genetic disease pathology

Deisseroth, C. A.; Lee, W.-S.; Kim, J.-Y.; Jeong, H.-H.; Wang, J.; Zoghbi, H. Y.; Liu, Z.

10.1101/2022.09.08.506253 — bioinformatics — Posted on 2022-09-12

2811 Weakly supervised Unet: an image classifier which learns to explain itself

O'Shea, R. J.; Horst, C.; Manickavasagar, T.; Hughes, D.; Cusack, J.; Tsoka, S.; Cook, G.; Goh, V.

10.1101/2022.09.09.507144 — bioinformatics — Posted on 2022-09-12

2812 Selection Of Models For The Regression Problems In Biology Using Chi-Square Test

Gupta, A. P.

10.1101/2022.09.08.507150 — bioengineering — Posted on 2022-09-12

2813 Injectable polymer-nanoparticle hydrogel for the sustained intravitreal delivery of bimatoprost

Meany, E. L.; Andaya, R.; Tang, S.; Kasse, C. M.; Fuji, R. N.; Grosskopf, A. K.; d'Aquino, A. l.; Bartoe, J. T.; Ybarra, R.; Shelton, A.; Pederson, Z.; Hu, C.; Leung, D.; Nagapudi, K.; Ubhayakar, S.; Wright, M.; Yen, C.-W.; Appel, E.

10.1101/2022.09.08.507193 — bioengineering — Posted on 2022-09-12

2814 Localized nanoparticle-mediated delivery of miR-29b normalises the dysregulation of bone homeostasis caused by osteosarcoma whilst simultaneously inhibiting tumour growth.

Freeman, F. E.; Dosta, P.; Riojas Javelly, C. J.; Mahon, O. R.; Kelly, D.; Artzi, N.

10.1101/2022.09.09.507272 — bioengineering — Posted on 2022-09-12

2815 28 Minutes Later: A behavioral and transcriptomic investigation into the potential role of aflatrem-like compounds in establishing Ophiocordyceps extended phenotypes in zombie ants

Beckeson, W. C.; Krider, C.; Mohammad, U. A.; de Bekker, C.

10.1101/2022.09.08.507134 — animal behavior and cognition — Posted on 2022-09-12

2816 Lionfish Pterois volitans can see UV light: UV Vision in an Invasive Aquatic Predator

Phillips, E. W.; de Wit, K. E.; Kotrschal, A.

10.1101/2022.09.09.507242 — animal behavior and cognition — Posted on 2022-09-12

2817 Refining epigenetic prediction of chronological and biological age

Bernabeu, E.; McCartney, D. L.; Gadd, D. A.; Hillary, R. F.; Lu, A. T.; Murphy, L.; Wrobel, N.; Campbell, A.; Harris, S. E.; Liewald, D.; Hayward, C.; Sudlow, C.; Cox, S. R.; Evans, K. L.; Horvath, S.; McIntosh, A. M.; Robinson, M. R.; Vallejos, C.; Marioni, R. E.

10.1101/2022.09.08.507115 — genomics — Posted on 2022-09-12

2818 MedDiC: high dimensional mediation analysis via difference in coefficients

Zhang, Q.; Yang, Z.; Yang, J.

10.1101/2022.09.08.507169 — genetics — Posted on 2022-09-12

2819 The SARS-CoV-2 Spike Protein Mutation Explorer: Using an Interactive Application to Improve the Public Understanding of SARS-CoV-2 Variants of Concern

Iannucci, S.; Harvey, W. T.; Hughes, J.; Robertson, D. L.; Poyade, M.; Hutchinson, E.

10.1101/2022.09.09.507349 — molecular biology — Posted on 2022-09-12

2820 Determinants restricting ACE2 recognition of MERS-related coronaviruses in bats

Ma, C.; Xiong, Q.; Gu, M.; Wang, C.; Shi, L.; Liu, C.; Si, J.; Tong, F.; Liu, P.; Huang, M.; Yan, H.

10.1101/2022.09.11.507506 — microbiology — Posted on 2022-09-12

2821 ISM-FLUX: MINFLUX with an array detector

Slenders, E.; Vicidomini, G.

10.1101/2022.04.19.488747 — biophysics — Posted on 2022-09-12

2822 Clomipramine inhibits dynamin L-α-phosphatidyl-L-serine stimulated GTPase activity

Miyoshi, H.; Otomo, M.; Takahashi, K.

10.1101/2022.09.09.507370 — biochemistry — Posted on 2022-09-12

2823 SERF deletion modifies amyloid aggregation in a mouse model of Alzheimer's disease

Stroo, E.; Janssen, L.; Sin, O.; Hogewerf, W.; Koster, M. H.; Harkema, L.; Youssef, S. A.; beschorner, N.; Wolters, A. H. G.; Bakker, B.; Thathiah, A.; Foijer, F.; van de Sluis, B.; van Deursen, J.; Jucker, M.; de Bruin, A.; Nollen, E.; Becker, L.; Garrett, L.; Marschall, S.; Hoelter, S.; Wurst, W.; Fuchs, H.; Gailus-Durner, V.; Hrabe de Angelis, M.

10.1101/2021.01.05.423442 — molecular biology — Posted on 2022-09-12

2824 Myoglobin-derived iron causes phagocyte dysfunction, wound enlargement, and impaired regeneration in pressure injuries of muscle

Nasir, N. J. M.; Heemskerk, H.; Jenkins, J. H.; Hamadee, N. H.; Bunte, R.; Tucker-Kellogg, L.

10.1101/2022.03.07.483146 — molecular biology — Posted on 2022-09-12

2825 Microbial community dynamics during a harmful Chrysochromulina leadbeateri bloom in northern Norway

Aalto, N. J.; Schweitzer, H.; Grann-Meyer, E.; Krsmanovic, S.; Svenning, J. B.; Dalheim, L.; Petters, S.; Ingebrigsten, R.; Hulatt, C. J.; Bernstein, H. C.

10.1101/2022.06.21.496960 — microbiology — Posted on 2022-09-12

2826 Various tomato cultivars display contrasted morphological and molecular responses to a heat wave.

Bollier, N.; Micol-Ponce, R.; Dakdaki, A.; Maza, E.; Zouine, M.; Djari, A.; Bouzayen, M.; Chevalier, C.; Delmas, F.; Gonzalez, N.; Hernould, M.

10.1101/2022.09.08.507118 — plant biology — Posted on 2022-09-12

2827 Amplicon structure creates collateral therapeutic vulnerability in cancer

Bei, Y.; Brame, L.; Kirchner, M.; Fritsche, R.; Kunz, S.; Bhattacharya, A.; Koeppke, J.; Proba, J.; Wittstruck, N.; Sidorova, O.; Chamorro, R.; Dorado Garcia, H.; Brueckner, L.; Xu, R.; Giurgiu, M.; Rodriguez-fos, E.; Koche, R.; Schmitt, C.; Schulte, J.; Eggert, A.; Haase, K.; Kirwan, J.; Heeren-Hagemann, A.; Mertins, P.; Doerr, J. R.; Henssen, A.

10.1101/2022.09.08.506647 — cancer biology — Posted on 2022-09-12

2828 Intrinsic apoptosis is evolutionarily divergent among metazoans

Krasovec, G.; Qeinnec, E.; Chambon, J.-P.

10.1101/2021.12.21.473695 — evolutionary biology — Posted on 2022-09-12

2829 Robust analysis of prokaryotic pangenome gene gain and loss rates with Panstripe

Tonkin-Hill, G.; Gladstone, R. A.; Pontinen, A. K.; Arredondo-Alonso, S.; Bentley, S. D.; Corander, J.

10.1101/2022.04.23.489244 — evolutionary biology — Posted on 2022-09-12

2830 A scenario-guided strategy for the future management of biological invasions

Roura-Pascual, N.; Saul, W.-C.; Perez-Granados, C.; Rutting, L.; Peterson, G. D.; Latombe, G.; Essl, F.; Adriaens, T.; Aldridge, D. C.; Bacher, S.; Bernardo-Madrid, R.; Brotons, L.; Diaz, F.; Gallardo, B.; Genovesi, P.; Golivets, M.; Gonzalez-Moreno, P.; Hall, M.; Kutlesa, P.; Lenzner, B.; Liu, C.; Pagitz, K.; Pastor, T.; Rabitsch, W.; Robertson, P.; Roy, H. E.; Seebens, H.; Solarz, W.; Starfinger, U.; Tanner, R.; Vila, M.; Leung, B.; Garcia-Lozano, C.; Jeschke, J. M.

10.1101/2022.09.07.506838 — ecology — Posted on 2022-09-12

2831 Interactions between culturable bacteria are highly non-additive

Baichman-Kass, A.; Song, T.; Friedman, J.

10.1101/2022.09.01.506178 — microbiology — Posted on 2022-09-12

2832 Relative pitch representations and invariance to timbre

McPherson, M. J.; McDermott, J. H.

10.1101/2022.01.13.476197 — neuroscience — Posted on 2022-09-12

2833 Neighbor-specific gene expression revealed from physically interacting cells during mouse embryonic development

Kim, J.; Rothov, M. M.; Madan, E.; Rhee, S.; Weng, G.; Palma, A. M.; Liao, L.; David, E.; Amit, I.; Hajkarim, M. C.; Gutierrez-Garcia, A.; Fisher, P. B.; Brickman, J. M.; Gogna, R.; Won, K. J.

10.1101/2021.12.02.470916 — developmental biology — Posted on 2022-09-12

2834 Post-Translational Tubulin Modifications in Differentiated Human Neural Stem Cells

Knight, V. B.; Jogalekar, M. P.; Serrano, E. E.

10.1101/2021.12.31.474563 — neuroscience — Posted on 2022-09-12

2835 Neogene climatic fluctuations and poor connectivity with the centres of diversity shaped the Western Palearctic net-winged beetle fauna

Motyka, M.; Kusy, D.; Bilkova, R.; Bocak, L.

10.1101/2022.09.08.507108 — zoology — Posted on 2022-09-12

2836 Spatial Transcriptome Profiling of Intraductal Papillary Mucinous Neoplasms Establishes a Molecular Framework for Risk Stratification

Allen, P. J.; Iyer, M. K.; Shi, C.; Eckhoff, A. M.; Fletcher, A.; Nussbaum, D. P.

10.1101/2022.09.08.507112 — cancer biology — Posted on 2022-09-12

2837 Comparative RNA-seq analysis of resistant and susceptible banana genotypes reveals molecular mechanisms in response to Banana bunchy top virus (BBTV)

Lantican, D. V.; Nocum, J. D. L.; Manohar, A. N. C.; Mendoza, J.-V. S.; Gardoce, R. R.; Lachica, G. C.; Gueco, L. S.; Dela Cueva, F. M.

10.1101/2022.09.08.507103 — genomics — Posted on 2022-09-12

2838 A systematic review of the effects of recreation on mammals and birds in mountains: Insights and future research directions

Hochreutener, A.; Rupf, R.; Pickering, C.; Signer, C.

10.1101/2022.09.08.507092 — ecology — Posted on 2022-09-12

2839 High diversity and sharing of strongylid nematodes in humans and great apes co-habiting unprotected area in Cameroon

Ilik, V.; Kreisinger, J.; Modry, D.; Schwarz, E. M.; Tagg, N.; Mbohli, D.; Charmance, N. I.; Petrzelkova, K. J.; Pafco, B.

10.1101/2022.09.08.507082 — ecology — Posted on 2022-09-12

2840 The high diversity of Scedosporium and Lomentospora species and their prevalence in human-disturbed areas in Taiwan

Huang, Y.-T.; Fan, Y.-C.; Hung, T.-C.; Chen, C.-Y.; Sun, P.-L.

10.1101/2022.06.10.495564 — microbiology — Posted on 2022-09-12

2841 Pyrfume: A Window to the World's Olfactory Data

Castro, J. B.; Gould, T. J.; Pellegrino, R.; Liang, Z.; Coleman, L. A.; Patel, F.; Wallace, D. S.; Bhatnagar, T.; Mainland, J. D.; Gerkin, R. C.

10.1101/2022.09.08.507170 — neuroscience — Posted on 2022-09-12

2842 Near-anoxia induces immobilisation and sustains viability of sperm in ant queens: Novel insights into mechanisms of prolonged sperm storage

Gotoh, A.; Takeshima, M.; Mizutani, K.-i.

10.1101/2022.09.08.507031 — zoology — Posted on 2022-09-12

2843 Researchers and their experimental models: A pilot survey.

Del Pace, L.; Viviani, L.; Straccia, M.

10.1101/2022.09.08.507094 — scientific communication and education — Posted on 2022-09-12

2844 Embryonic Vitamin D Deficiency Programs Hematopoietic Stem Cells to Induce Type 2 Diabetes

Bernal-Mizrachi, C.; Oh, J.; Riek, A. E.; Bauerle, K. T.; Dusso, A.; McNerney, K.; Barve, R.; Darwech, I.; Sprague, J.; Moynihan, C.; Zhang, R. M.; Wang, T.; Xing, X.; Li, D.; Head, R. D.; Bambouskova, M.; Mrad, M.; Collins, A.; Sands, M. S.

10.1101/2022.09.08.507174 — physiology — Posted on 2022-09-12

2845 F1F0 ATP Hydrolysis is a Determinant of Metabolic Rate, a Correlate of Lifespan, and a Weakness of Cancer

Forrest, M. D.

10.1101/2021.10.28.466310 — pharmacology and toxicology — Posted on 2022-09-12

2846 Paired evaluation defines performance landscapes for machine learning models

Nariya, M. K.; Mills, C. E.; Sorger, P. K.; Sokolov, A.

10.1101/2022.09.07.507020 — bioinformatics — Posted on 2022-09-12

2847 Microbial metabolite butyrate-prodrug polymeric micelles demonstrate therapeutic efficacy in pre-clinical models of food allergy and colitis

Wang, R.; Cao, S.; Bashir, M. E. H.; Hesser, L. A.; Su, Y.; Hong, S. M. C.; Thompson, A.; Culleen, E.; Sabados, M.; Dylla, N. P.; Campbell, E.; Bao, R.; Nonnecke, E. B.; Bevins, C. L.; Wilson, D. S.; Hubbell, J. A.; Nagler, C. R.

10.1101/2022.05.01.490224 — bioengineering — Posted on 2022-09-12

2848 Modelling how the altered usage of cell entry pathways by the SARS-CoV-2 Omicron variant may affect the efficacy and synergy of TMPRSS2 and Cathepsin B/L inhibitors

Padmanabhan, P.; Dixit, N. M.

10.1101/2022.01.13.476267 — microbiology — Posted on 2022-09-12

2849 Decision-making in dynamic, continuously evolving environments: quantifying the flexibility of human choice

Ruesseler, M.; Weber, L. A.; Marshall, T. R.; O'Reilly, J. X.; Hunt, L. T.

10.1101/2022.08.18.504278 — neuroscience — Posted on 2022-09-12

2850 Spatial tuning in nociceptive processing is driven by attention

Adamczyk, W. M.; Katra, M.; Szikszay, T.; Peugh, J.; King, C.; Luedtke, K.; Coghill, R. C.

10.1101/2022.06.16.496352 — neuroscience — Posted on 2022-09-12

2851 Tilt In Place Microscopy (TIPM): a simple, low-cost solution to image neural responses to body rotations

Hamling, K. R.; Zhu, Y.; Auer, F.; Schoppik, D.

10.1101/2022.09.11.507428 — neuroscience — Posted on 2022-09-12

2852 Empirical methods for the validation of Time-To-Event mathematical models taking into account uncertainty and variability: Application to EGFR+ Lung Adenocarcinoma.

Jacob, E.; Perrillat-Mercerot, A.; Palgen, J.-L.; L'Hostis, A.; Ceres, N.; Boissel, J.-P.; Bosley, J.; Monteiro, C.; Kahoul, R.

10.1101/2022.09.08.507079 — systems biology — Posted on 2022-09-12

2853 Systematic Bayesian posterior analysis guided by Kullback-Leibler divergence facilitates hypothesis formation

Huber, H. A.; Georgia, S. K.; Finley, S. D.

10.1101/2022.07.14.500054 — systems biology — Posted on 2022-09-12

2854 DOTA chelation through click chemistry enables favorable biodistribution of 89Zr-radiolabeled antibodies: A comparison with DFO chelation

Imura, R.; Kumakura, Y.; Yan, L.; Shimoura, Y.; Takahashi, H.; Ida, H.; Wada, Y.; Akimitsu, N.

10.1101/2022.09.08.507067 — cancer biology — Posted on 2022-09-12

2855 Mathematical bridge between epidemiological and molecular data on cancer and beyond

Chakravarty, S.; Islam, K. A.; Mohtashim, S. I.

10.1101/2022.09.07.507053 — cancer biology — Posted on 2022-09-12

2856 Meta-analysis of the public RNA-Seq data of the Western honeybee Apis mellifera to construct reference transcriptome data

Yokoi, K.; Wakamiya, T.; Bono, H.

10.1101/2022.09.07.506879 — bioinformatics — Posted on 2022-09-12

2857 Progression Analysis of Disease with Survival (PAD-S) by SurvMap identifies different prognostic subgroups of breast cancer in a large combined set of transcriptomics and methylation studies

Fores Martos, J.; Suay-Garcia, B.; Bosch-Romeu, R.; Sanfeliu-Alonso, M. C.; Falco, A.; Climent, J.

10.1101/2022.09.08.507080 — bioinformatics — Posted on 2022-09-12

2858 Live visualization of endoplasmic reticulum redox potential in zebrafish embryos reveals region-specific differences

Verma, M.; Bhatt, N. R.; Chaphalkar, A.; Verma, K.; Umale, S.; Verma, S.; Sachidanandan, C.; Chakraborty, K.

10.1101/2022.02.12.480199 — biochemistry — Posted on 2022-09-12

2859 Calcium homeostasis disruption initiates rapid growth after micro-fragmentation in the scleractinian coral Porites lobata

Lock, C.; Bentlage, B.; Raymundo, L. J.

10.1101/2022.02.28.482414 — genetics — Posted on 2022-09-12

2860 Identifying opportunities for high resolution pesticide usage data to improve the efficiency of endangered species pesticide risk assessment

Eikenberry, S. E.; Iacona, G.; Murphy, E. L.; Watson, G.; Gerber, L. R.

10.1101/2022.09.07.507030 — ecology — Posted on 2022-09-12

2861 Heat dissipation drives the hump-shaped scaling of animal dispersal speed with body mass

Dyer, A.; Brose, U.; Berti, E.; Rosenbaum, B.; Hirt, M.

10.1101/2022.09.08.507078 — ecology — Posted on 2022-09-12

2862 Exploring the mismatch between the theory and application of photosynthetic quotients in aquatic ecosystems

Trentman, M. T.; Hall, R. O.; Valett, H. M.

10.1101/2022.09.07.507017 — ecology — Posted on 2022-09-12

2863 LncRNA Malat1 represses Th17 effector program by maintaining a critical bivalent super-enhancer and promotes intestinal inflammation

Ma, S.; Zhou, B.; Abe, Y.; Chen, N.; Luo, C.; Li, Y.; Patel, P. R.; Zheng, A.; Patel, S. A.; Hao, Y.; Chang, J. T.; Fu, X.; Huang, W. J. M.

10.1101/2022.03.21.485192 — immunology — Posted on 2022-09-12

2864 Mice with humanized livers reveal the involvement of hepatocyte circadian clocks in rhythmic behavior and physiology

Delbes, A.-S.; Quinones, M.; Gobet, C.; Castel, J.; Denis, R. G. P.; Jeremy, B.; Weger, B. D.; Challet, E.; Charpagne, A.; Metairon, S.; Piccand, J.; Kraus, M.; Rohde, B.; Bial, J.; Wilson, E. M.; Vedin, L.-L.; Minniti, M. E.; Pedrelli, M.; Parini, P.; Gachon, F.; Luquet, S. H.

10.1101/2022.09.08.506890 — physiology — Posted on 2022-09-12

2865 A widely-used pollutant causes reversal of conspecific mate preference in a freshwater fish

Powell, D. L.; Rose, A. D.; Rosenthal, G. G.

10.1101/2022.09.07.507014 — animal behavior and cognition — Posted on 2022-09-12

2866 Dimerization of iLID Optogenetic Proteins Observed Using 3D Single-Molecule Tracking in Live Bacterial Cells

Achimovich, A. M.; Yan, T.; Gahlmann, A.

10.1101/2022.07.10.499479 — biophysics — Posted on 2022-09-12

2867 Cocaine addiction-like behaviors are associated with long-term changes in gene regulation, energy metabolism, and GABAergic inhibition within the amygdala

Zhou, J. L.; de Guglielmo, G.; Ho, A. J.; Kallupi, M.; Li, H.-R.; Chitre, A. S.; Carrette, L. L. G.; George, O.; Palmer, A. A.; McVicker, G. P.; Telese, F.

10.1101/2022.09.08.506493 — genomics — Posted on 2022-09-12

2868 Haplotype-resolved assemblies and variant benchmark of a Chinese Quartet

Jia, P.; Dong, L.; Yang, X.; Wang, B.; Wang, T.; Lin, J.; Wang, S.; Zhao, X.; Xu, T.; Che, Y.; Dang, N.; Ren, L.; Zhang, Y.; Wang, X.; Liang, F.; Wang, Y.; Ruan, J.; The Quartet Project Team, ; Zheng, Y.; Shi, L.; Wang, J.; Ye, K.

10.1101/2022.09.08.504083 — genomics — Posted on 2022-09-12

2869 HRDex: a tool for deriving homologous recombination deficiency (HRD) scores from whole exome sequencing data

Pluta, J.; Hausler, R.; Wubbenhorst, B.; Desai, H.; Domchek, S. M.; Nathanson, K. L.; Maxwell, K. N.

10.1101/2022.09.08.506670 — genomics — Posted on 2022-09-12

2870 Sedimentary DNA can reveal past pelagic copepod population dynamics

Nakane, K.; Liu, X.; Doi, H.; Dur, G.; Kuwae, M.; Ban, S.; Tsugeki, N.

10.1101/2022.09.09.506697 — ecology — Posted on 2022-09-12

2871 Emergence of flagella-like oscillations in single microtubules driven by collective dynein transport

Yadav, S. A.; Khetan, N.; Khatri, D.; Athale, C. A.

10.1101/2022.09.11.507451 — biophysics — Posted on 2022-09-12

2872 Synthesizing Images of Tau Pathology from Cross-modal Neuroimaging using Deep Learning

Lee, J.; Burkett, B. J.; Min, H.-K.; Senjem, M. L.; Dicks, E.; Corriveau-Lecavalier, N.; Mester, C. T.; Wiste, H. J.; Lundt, E. S.; Murray, M. E.; Nguyen, A. T.; Reichard, R. R.; Botha, H.; Graff-Radford, J.; Barnard, L. R.; Gunter, J. L.; Schwarz, C. G.; Kantarci, K.; Knopman, D. S.; Boeve, B. F.; Lowe, V. J.; Petersen, R. C.; Jack, C. R.; Jones, D. T.

10.1101/2022.09.07.507042 — bioengineering — Posted on 2022-09-12

2873 Localization of multiple hydrogels with MultiCUBE platform spatially guides 3D tissue morphogenesis in vitro

Suthiwanich, K.; Hagiwara, M.

10.1101/2022.09.08.507064 — bioengineering — Posted on 2022-09-12

2874 Targeting extracellular vesicle delivery to the lungs by microgel encapsulation

Cober, N. D.; Rowe, K.; Deng, Y.; Benavente-Babace, A.; Courtman, D. W.; Godin, M.; Stewart, D. J.

10.1101/2022.09.09.507125 — bioengineering — Posted on 2022-09-12

2875 A high-quality chromosome-level genome assembly of rohu carp, Labeo rohita, and its utilization in SNP-based exploration of gene flow and sex determination

Arick, M. A.; Grover, C. E.; Hsu, C.-Y.; Magbanua, Z. V.; Pechanova, O.; Miller, E. R.; Thrash, A.; Youngblood, R. C.; Ezzell, L.; Alam, M. S.; Benzie, J. A. H.; Hamilton, M. G.; Karsi, A.; Lawrence, M. L.; Peterson, D. G.

10.1101/2022.09.08.507226 — genomics — Posted on 2022-09-12

2876 High-throughput TCRB enrichment sequencing of human cord blood exhibited a distinct fetal T cell repertoire in the third trimester of pregnancy

Dong, Y.; Wei, C.; Wang, J.; Wu, X.; Zhao, Y.; Cai, Y.; Han, Y.; Wang, Y.; Li, H.; Qiao, J.; Yuan, W.

10.1101/2022.09.08.506871 — genetics — Posted on 2022-09-12

2877 Perturbations in podocyte transcriptome and biological pathways induced by FSGS associated circulating factors.

Rashmi, P.; Sigdel, T. K.; Rychkov, D.; Damm, I.; da Silva, A. A.; Vincenti, F.; Lourenco, A. L.; Craik, C. S.; Reiser, J.; Sarwal, M. M.

10.1101/2022.09.08.507168 — immunology — Posted on 2022-09-12

2878 Locus-specific proteomics identifies new aspects of the chromatin context involved in V region somatic hypermutation

Yu, G.; Duan, Z.; Zhang, Y.; Aguilan, J.; Sidoli, S.; Scharff, M. D.

10.1101/2022.09.08.507190 — immunology — Posted on 2022-09-12

2879 CD4-binding site immunogens elicit heterologous anti-HIV-1 neutralizing antibodies in transgenic and wildtype animals

Gristick, H. B.; Hartweger, H.; Loewe, M.; van Schooten, J.; Ramos, V.; Oliviera, T. Y.; Nishimura, Y.; Koranda, N. S.; Wall, A.; Yao, K.-H.; Poston, D.; Gazumyan, A.; Wiatr, M.; Horning, M.; Keeffe, J. R.; Hoffmann, M. A.; Yang, Z.; Abernathy, M. E.; Dam, K.-M. A.; Gao, H.; Gnanapragasam, P. N.; Kakutani, L. M.; Pavlovitch-Bedzyk, A. J.; Seaman, M. S.; Howarth, M.; McGuire, A. T.; Stamatatos, L.; Martin, M. A.; West, A. P.; Nussenzweig, M. C.; Bjorkman, P. J.

10.1101/2022.09.08.507086 — immunology — Posted on 2022-09-12

2880 A common human MLKL polymorphism confers resistance to negative regulation by phosphorylation

Garnish, S. E.; Martin, K. R.; Kauppi, M.; Jackson, V.; Ambrose, R.; Eng, V. V.; Frank, D.; Tovey Crutchfield, E. C.; Patel, K. M.; Chiou, S.; Samson, A. L.; Doerflinger, M.; Horne, C. R.; Hall, C.; Young, S. N.; Athanasopoulos, V.; Vinuesa, C. G.; Slade, C. A.; Pearson, J. S.; Ebert, G.; Silke, J.; Murphy, J. M.; Hildebrand, J.

10.1101/2022.09.08.507056 — immunology — Posted on 2022-09-12

2881 Natural killer cell-mimic nanoparticles can actively target and kill acute myeloid leukemia cells

Alizadeh Zeinabad, H.; Yeoh, W. J.; Lomora, M.; Banz, Y.; Riether, C.; Krebs, P.; Szegezdi, E.

10.1101/2022.09.09.507236 — cancer biology — Posted on 2022-09-11

2882 Amyloidogenic Propensity of Self-Assembling Peptides and their Adjuvant Potential for use as DNA Vaccines

Shrimali, P.; Chen, S.; Dreher, R.; Howard, M.; Buck, J.; Kim, D.; Rudra, J.; Jackrel, M.

10.1101/2022.09.09.507367 — bioengineering — Posted on 2022-09-11

2883 Multilayer Networks of Plasmid Genetic Similarity Reveal Potential Pathways of Gene Transmission

Shapiro, J. T.; Zorea, A.; Brown Kav, A.; Ontiveros, V. J.; Mizrahi, I.; Pilosof, S.

10.1101/2022.09.08.507140 — ecology — Posted on 2022-09-11

2884 Identifying Pathogen and Allele Type Simultaneously (IPATS) in a single well using droplet digital PCR

Notsu, K.; El Daous, H.; Mitoma, S.; Wu, X.; Norimine, J.; Sekiguchi, S.

10.1101/2022.09.10.507438 — microbiology — Posted on 2022-09-11

2885 Analysis of transcriptome datasets reveals involvement of epithelial-mesenchymal transition genes in small cell lung cancer phenotypic plasticity

Groves, S. M.; Panchy, N.; Tyson, D. R.; Harris, L. A.; Quaranta, V.; Hong, T.

10.1101/2022.09.09.507376 — cancer biology — Posted on 2022-09-11

2886 Scaling protein-water interactions in the Martini 3 coarse-grained force field to simulate transmembrane helix dimers in different lipid environments

Claveras Cabezudo, A.; Athanasiou, C.; Tsengenes, A.; Wade, R. C.

10.1101/2022.09.09.506752 — biophysics — Posted on 2022-09-11

2887 Study on the interactions between cisplatin and cadherin

Sun, J.; Wang, X.; Shao, K.-; Zhi, H.; Lin, Y.; Liu, Z.

10.1101/2022.09.11.507507 — biochemistry — Posted on 2022-09-11

2888 Ceramide-1-phosphate transfer protein enhances lipid transport by disrupting hydrophobic lipid-membrane contacts

Rogers, J. R.; Geissler, P. L.

10.1101/2022.09.10.507427 — biophysics — Posted on 2022-09-11

2889 G-quadruplexes rescuing protein folding

Son, A.; Huizar Cabral, V.; Litberg, T. J.; Horowitz, S.

10.1101/2022.09.09.507295 — biophysics — Posted on 2022-09-11

2890 Crystal structure of Vibrio cholerae (6-4) photolyase with DNA binding region

Cakilkaya, B.; Kavakli, I. H.; DeMirci, H.

10.1101/2022.09.10.507404 — molecular biology — Posted on 2022-09-11

2891 Malian children infected with Plasmodium ovale and Plasmodium falciparum display very similar gene expression profiles.

Tebben, K.; Yirampo, S.; Coulibaly, D.; Kone, A. K.; Laurens, M. B.; Stucke, E.; Dembele, A.; Tolo, Y.; Traore, K.; Niangaly, A.; Berry, A. A.; Kouriba, B.; Plowe, C. V.; Doumbo, O. K.; Lyke, K. E.; Takala-Harrison, S.; Thera, M. A.; Travassos, M. A.; Serre, D.

10.1101/2022.09.09.507248 — microbiology — Posted on 2022-09-11

2892 Targeting intracellular Neu1 for Coronavirus Infection Treatment

Yang, D.; Wu, Y.; Turan, I.; Keil, J.; Li, K.; Chen, M. H.; Liu, R.; Wang, L.; Sun, X.-L.; Chen, G.

10.1101/2022.09.09.507342 — microbiology — Posted on 2022-09-11

2893 Treatment with anti-inflammatory viral serpin modulates immuno-thrombotic responses and improves outcomes in SARS-CoV-2 infected mice

Zhang, L.; Li, Y. H.; Kibler, K.; Kraberger, S.; Varsani, A.; Turk, J.; Elmadbouly, N.; Aliskevich, E.; Spaccarelli, L.; Estifanos, B.; Enow, J.; Zanetti, I. R.; Saldevar, N.; Lim, E.; Browder, K.; Wilson, A.; Juan, F. A.; Pinteric, A.; Garg, A.; Gisriel, S.; Jacobs, B.; Karr, T. L.; Florsheim, E. B.; Kumar, V.; Wallen, J.; Rahman, M.; McFadden, D. G.; Hogue, B.; Lucas, A. R.

10.1101/2022.09.09.507363 — microbiology — Posted on 2022-09-11

2894 Cross-biome microbial networks reveal functional redundancy and suggest genome reduction through functional complementarity

Puente-Sanchez, F.; Pascual-Garcia, A.; Bastolla, U.; Pedros-Alio, C.; Tamames, J.

10.1101/2022.09.11.507163 — microbiology — Posted on 2022-09-11

2895 NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Pacl, H. T.; Chinta, K. C.; Reddy, V. P.; Nadeem, S.; Sevalkar, R. R.; Nargan, K.; Lumamba, K.; Naidoo, T.; Glasgow, J. N.; Agarwal, A.; Steyn, A. J. C.

10.1101/2022.09.11.507472 — microbiology — Posted on 2022-09-11

2896 A stochastic model of cortical microtubule anchoring and mechanics provides regulatory control of microtubule shape

Tian, T. Y. Y.; Macdonald, C. B.; Cytrynbaum, E. N.

10.1101/2022.09.08.507191 — biophysics — Posted on 2022-09-11

2897 An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options

Kang, J. Y.; Mishanina, T. V.; Bao, Y.; Chen, J.; Llewellyn, E.; Liu, J.; Darst, S. A.; Landick, R.

10.1101/2022.09.11.507475 — biochemistry — Posted on 2022-09-11

2898 Conformational Changes Regulate Metal Coordination in the Catalytic Sites of Cas9

Das, A.; Rai, J.; Roth, M. O.; Shu, Y.; Medina, M. L.; Barakat, M. R.; Li, H.

10.1101/2022.09.10.507422 — biochemistry — Posted on 2022-09-11

2899 Branch point evolution controls species-specific alternative splicing and regulates long term potentiation

Franz, A.; Weber, A. I.; Preussner, M.; Dimos, N.; Stumpf, A.; Ji, Y.; Velasquez, L. M.; Voigt, A.; Schulz, F.; Neumann, A.; Kuropka, B.; Kühn, R.; Urlaub, H.; Schmitz, D.; Wahl, M.; Heyd, F.

10.1101/2022.09.09.507289 — molecular biology — Posted on 2022-09-11

2900 Regulatory and evolutionary annotation identifies KAN1, MYB44 and PIF4 as regulators of Arabidopsis lincRNAs expressed in root

Liu, L.; Heidecker, M.; Depuydt, T.; Manosalva Perez, N.; Crespi, M.; Blein, T.; Vandepoele, K.

10.1101/2022.09.09.507345 — plant biology — Posted on 2022-09-11

2901 Improving biome labeling for tens of thousands of inaccurately annotated microbial community samples based on neural network and transfer learning

Wang, N.; Wang, T.; Ning, K.

10.1101/2022.09.09.507244 — bioinformatics — Posted on 2022-09-11

2902 Modulating the Kynurenine pathway or sequestering toxic 3-hydroxykynurenine protects the retina from light induced damage in Drosophila

Hebbar, S.; Traikov, S.; Hälsig, C.; Knust, E.

10.1101/2022.09.10.507411 — genetics — Posted on 2022-09-11

2903 Functional characterization of the Co2+ transporter AitP in Sinorhizobium meliloti: a new player in Fe2+ homeostasis

Mihelj, P.; Abreu, I.; Moreyra, T. E.; Gonzalez-Guerrero, M.; Raimunda, D. C.

10.1101/2022.09.08.507232 — microbiology — Posted on 2022-09-11

2904 Altered visual cortex excitability in premenstrual dysphoric disorder: evidence from magnetoencephalographic gamma oscillations and perceptual suppression

Manyukhina, V. O.; Orekhova, E. V.; Prokofyev, A. O.; Obukhova, T. S.; Stroganova, T. A.

10.1101/2022.09.06.506748 — neuroscience — Posted on 2022-09-11

2905 Evolutionary and cellular analysis of the dark pseudokinase PSKH2

Byrne, D. P.; Shrestha, S.; Daly, L. A.; Marensi, V.; Ramakrishnan, K.; Eyers, C. E.; Kannan, N.; Eyers, P. A.

10.1101/2022.09.10.507278 — biochemistry — Posted on 2022-09-11

2906 An ImageJ-based tool for three-dimensional registration between different types of microscopic images

Koyama, H.; Kishi, K.; Fujimori, T.

10.1101/2022.09.11.507445 — developmental biology — Posted on 2022-09-11

2907 CP204L Is a Multifunctional Protein of African Swine Fever Virus That Interacts with The VPS39 Subunit of HOPS Complex and Promotes Lysosome Clustering

Dolata, K. M.; Fuchs, W.; Caignard, G.; Dupre, J.; Pannhorst, K.; Blome, S.; Mettenleiter, T. C.; Karger, A.

10.1101/2022.09.09.507285 — microbiology — Posted on 2022-09-11

2908 Metaplasticity: Dark exposure boosts excitability and visual plasticity in adult human cortex

Min, S. H.; Wang, Z.; Chen, M.; Hu, R.; Gong, L.; He, Z.; Wang, X.; Hess, R. F.; Zhou, J.

10.1101/2022.09.04.506561 — neuroscience — Posted on 2022-09-11

2909 Neural Representations of Self-Generated Thought during Think-aloud fMRI

Li, H.-X.; Lu, B.; Wang, Y.-W.; Li, X.-Y.; Chen, X.; Yan, C.-G.

10.1101/2022.02.15.480505 — neuroscience — Posted on 2022-09-11

2910 Amplicon structure creates collateral therapeutic vulnerability in cancer

10.1101/2022.09.08.506647 — cancer biology — Posted on 2022-09-11

2911 ARHGEF18 participates in Endothelial Cell Mechano-sensitivity in Response to Flow

Batta, S. P. R.; Rio, M.; Lebot, C.; Baron-Menguy, C.; Le Ruz, R.; Loirand, G.; Vion, A.-C.

10.1101/2022.09.10.507283 — cell biology — Posted on 2022-09-11

2912 Trajectory classification method for anchored molecular motor-biopolymer interactions in the C. elegans first mitosis.

Linehan, J. B.; Edwards, A.; Boudreau, V.; Maddox, P.

10.1101/2022.09.11.507465 — cell biology — Posted on 2022-09-11

2913 Minute-scale Periodicity of Neuronal Firing in the Human Entorhinal Cortex

M. Aghajan, Z.; Kreiman, G.; Fried, I.

10.1101/2022.05.05.490703 — neuroscience — Posted on 2022-09-11

2914 Mutational Landscape of Cancer-Driver Genes Across Human Cancers

Sinkala, M.

10.1101/2022.09.11.507448 — bioinformatics — Posted on 2022-09-11

2915 SPUMONI 2: Improved pangenome classification using a compressed index of minimizer digests

Ahmed, O.; Rossi, M.; Gagie, T.; Boucher, C.; Langmead, B.

10.1101/2022.09.08.506805 — bioinformatics — Posted on 2022-09-11

2916 SETH predicts nuances of residue disorder from protein embeddings

Ilzhoefer, D.; Heinzinger, M.; Rost, B.

10.1101/2022.06.23.497276 — bioinformatics — Posted on 2022-09-11

2917 CAPG: Comprehensive Allopolyploid Genotyper

Kulkarni, R.; Zhang, Y.; Cannon, S. B.; Dorman, K. S.

10.1101/2022.04.21.488948 — bioinformatics — Posted on 2022-09-11

2918 Inferring sources of suboptimality in perceptual decision making using a causal inference task

Shivkumar, S.; Cappelloni, M. S.; Maddox, R. K.; Haefner, R. M.

10.1101/2022.04.28.489925 — animal behavior and cognition — Posted on 2022-09-11

2919 When good species have porous boundaries: weak reproductive isolation and extensive gene flow between Mimulus glaucescens and M. guttatus in northern California

Ivey, C.; Habecker, N.; Bergmann, J. P.; Ewald, J.; Coughlan, J. M.

10.1101/2022.09.08.507212 — evolutionary biology — Posted on 2022-09-11

2920 Dispersal inference from population genetic variation using a convolutional neural network

Smith, C. C. R.; Tittes, S.; Ralph, P. L.; Kern, A. D.

10.1101/2022.08.25.505329 — evolutionary biology — Posted on 2022-09-11

2921 Intrinsic apoptosis is evolutionarily divergent among metazoans

Krasovec, G.; Qeinnec, E.; Chambon, J.-P.

10.1101/2021.12.21.473695 — evolutionary biology — Posted on 2022-09-11

2922 Formal Recognition and Classification of Gene Transfer Agents as Viriforms

Kogay, R.; Koppenhofer, S.; Beatty, J. T.; Lang, A. S.; Kuhn, J. H.; Zhaxybayeva, O.

10.1101/2022.06.10.494566 — evolutionary biology — Posted on 2022-09-11

2923 Multiple climate change factors jointly increase the competitiveness of a C4 grass against its C3 competitor

Hsu, G.-C.; Ke, P.-J.; Ho, C.-K.

10.1101/2022.09.01.506280 — ecology — Posted on 2022-09-11

2924 A single cell atlas of the cycling murine ovary

Morris, M. E.; Meinsohn, M.-C.; Chauvin, M.; Saatcioglu, H. D.; Kashiwagi, A.; Sicher, N. A.; Nguyen, N.; Yuan, S.; Stavely, R. G.; Hyun, M.; Donahoe, P. K.; Sabatini, B. L.; Pepin, D.

10.1101/2022.02.08.479522 — developmental biology — Posted on 2022-09-11

2925 Characterization of TelE, an LXG effector of Streptococcus gallolyticus, antagonized by a non-canonical immunity protein

Teh, W. K.; Ding, Y.; Gubellini, F.; Filloux, A.; Poyart, C.; Dramsi, S.; Givskov, M.

10.1101/2022.09.07.506920 — microbiology — Posted on 2022-09-11

2926 Quantitative single-cell analysis of Leishmania major amastigote differentiation demonstrates variably extended expression of the lipophosphoglycan (LPG) virulence factor in different host cell types

Mandell, M. A.; Beatty, W. L.; Beverley, S. M.

10.1101/2022.06.27.497826 — microbiology — Posted on 2022-09-11

2927 Computing Minimal Boolean Models of Gene Regulatory Networks

Karlebach, G.; Robinson, P. N.

10.1101/2021.05.22.445266 — systems biology — Posted on 2022-09-11

2928 Motor and cognitive deficits limit the ability to flexibly modulate spatiotemporal gait features in older adults with mild cognitive impairment

Rosenberg, M. C.; Slusarenko, A.; Cao, K.; McKay, J. L.; Emmery, L.; Kesar, T. M.; Hackney, M. E.

10.1101/2022.09.09.507368 — synthetic biology — Posted on 2022-09-11

2929 CTCF is a DNA-tension-dependent barrier to cohesin-mediated DNA loop extrusion

Davidson, I. F.; Barth, R.; Zaczek, M.; van der Torre, J.; Tang, W.; Nagasaka, K.; Janissen, R.; Kerssemakers, J.; Wutz, G.; Dekker, C.; Peters, J.-M.

10.1101/2022.09.08.507093 — biophysics — Posted on 2022-09-11

2930 High Resolution Biomolecular Condensate Phase Diagrams with a Combinatorial Microdroplet Platform

Arter, W. E.; Qi, R.; Erkamp, N. A.; Krainer, G.; Didi, K.; Welsh, T. J.; Acker, J.; Nixon-Abell, J.; Qamar, S.; Guillen-Boixet, J.; Franzmann, T. M.; Kuster, D.; Hyman, A. A.; Borodavka, A.; St George-Hyslop, P.; Alberti, S.; Knowles, T. P.

10.1101/2020.06.04.132308 — biophysics — Posted on 2022-09-11

2931 Tethered agonist activated ADGRF1 structure reveals molecular preference for Gq signaling

Jones, D. T. D.; Dates, A. N.; Rawson, S. D.; Burruss, M. M.; Lipper, C. H.; Blacklow, S. C.

10.1101/2022.09.09.507336 — biochemistry — Posted on 2022-09-11

2932 Botrytis cinerea strains infecting grapevine and tomato display contrasted repertoires of accessory chromosomes, transposons and small RNAs

Simon, A.; Mercier, A.; Gladieux, P.; Poinssot, B.; Walker, A.-S.; Viaud, M.

10.1101/2022.03.07.483234 — genomics — Posted on 2022-09-11

2933 Partitioning Marginal Epistasis Distinguishes Nonlinear Effects from Polygenicity and Other Biases in GWA Summary Statistics

Darnell, G.; Smith, S. P.; Udwin, D.; Ramachandran, S.; Crawford, L.

10.1101/2022.07.21.501001 — genetics — Posted on 2022-09-11

2934 OGT controls mammalian cell viability by regulating the proteasome/mTOR/mitochondrial axis

Li, X.; Yue, X.; Sepulveda, H.; Burt, R. A.; Scott, D. A.; Carr, S. A.; Myers, S. A.; Rao, A.

10.1101/2021.09.19.461012 — cell biology — Posted on 2022-09-11

2935 Analysis and Exploration of the Implementation System of Mixed Ownership of Scientific and Technological Achievements in Colleges and Universities

Gao, P.; Qi, Y.; Guo, Q.

10.1101/2022.09.04.506550 — scientific communication and education — Posted on 2022-09-11

2936 Analysis of Body-Fin Cooperative Propulsion Mechanism of Koi Carp Using Pose Estimation

Wu, X.; Hua, M.; Wang, L.

10.1101/2022.09.07.507033 — animal behavior and cognition — Posted on 2022-09-11

2937 Circulating tumor DNA profiling approach based on in silico background elimination guides patient classification of multiple cancers

Li, M.; Xie, S.; Hou, T.; Shao, T.; Kuang, J.; Lu, C.; Liu, X.; Zhu, L.; Zhu, L.

10.1101/2022.08.04.502459 — cancer biology — Posted on 2022-09-11

2938 MEBOCOST: Metabolite-mediated Cell Communication Modeling by Single Cell Transcriptome

Zheng, R.; Zhang, Y.; Tsuji, T.; Gao, X.; Wagner, A.; Yosef, N.; Cheng, H.; Zhang, L.; Tseng, Y.-H.; Chen, K.

10.1101/2022.05.30.494067 — bioinformatics — Posted on 2022-09-11

2939 Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire

Rodriguez, O. L.; Safonova, Y.; Silver, C. A.; Shields, K.; Gibson, W. S.; Kos, J. T.; Tieri, D.; Ke, H.; Jackson, K. J. L.; Boyd, S. D.; Smith, M.; Marasco, W.; Watson, C. T.

10.1101/2022.07.04.498729 — genomics — Posted on 2022-09-11

2940 Origin and diversification of fibroblasts from the sclerotome in zebrafish

Ma, R. C.; Kocha, K. M.; Mendez-Olivos, E. E.; Ruel, T. D.; Huang, P.

10.1101/2021.04.19.440421 — developmental biology — Posted on 2022-09-11

2941 Structure and Function of Gli123 Involved in Mycoplasma mobile Gliding

Matsuike, D.; Tahara, Y. O.; Nonaka, T.; Wu, H. N.; Hamaguchi, T.; Kudo, H.; Hayashi, Y.; Arai, M.; Miyata, M.

10.1101/2022.09.07.507039 — microbiology — Posted on 2022-09-11

2942 Optimal Control Costs of Brain State Transitions in Linear Stochastic Systems

Kamiya, S.; Kawakita, G.; Sasai, S.; Kitazono, J.; Oizumi, M.

10.1101/2022.05.01.490252 — neuroscience — Posted on 2022-09-11

2943 Longitudinal effects of using and discontinuing CNS medications on cognitive functioning

Koch, E.; Johnell, K.; Kauppi, K.

10.1101/2021.09.13.460082 — pharmacology and toxicology — Posted on 2022-09-11

2944 Evolution and change: a principle of least selection

Yarus, M.

10.1101/2021.06.27.450095 — evolutionary biology — Posted on 2022-09-11

2945 Zebrafish Slit2 and Slit3 act together to regulate retinal axon crossing at the midline

Davison, C.; Bedo, G.; Zolessi, F. R.

10.1101/2022.08.12.503757 — developmental biology — Posted on 2022-09-11

2946 Ethanol Exposure Perturbs Sea Urchin Development and Disrupts Developmental Timing

Rodriguez-Sastre, N.; Shapiro, N.; Hawkins, D. Y.; Lion, A. T.; Peyreau, M.; Correa, A. E.; Dionne, K.; Bradham, C.

10.1101/2022.07.07.499183 — developmental biology — Posted on 2022-09-11

2947 NetAct: a computational platform to construct core transcription factor regulatory networks using gene activity

Su, K.; Katebi, A. R.; Kohar, V. R.; Clauss, B.; Gordin, D.; Qin, Z.; Karuturi, R. K. M.; Li, S.; Lu, M.

10.1101/2022.05.06.487898 — systems biology — Posted on 2022-09-11

2948 Spread the word about freshwater mussels' conservation: Increasing awareness and willingness to support conservation-oriented policies through social media

Ferreira-Rodriguez, N.

10.1101/2022.09.09.507251 — scientific communication and education — Posted on 2022-09-11

2949 Specimen, Biological Structure, and Spatial Ontologies in Support of a Human Reference Atlas

Herr, B. W.; Hardi, J.; Quardokus, E. M.; Bueckle, A. D.; Caron, A. R.; Chen, L.; Wang, F.; Osumi-Sutherland, D.; Musen, M. A.; Borner, K.

10.1101/2022.09.08.507220 — bioinformatics — Posted on 2022-09-11

2950 Predicting microbial community compositions in wastewater treatment plants using artificial neural networks

Liu, X.; Nie, Y.; Wu, X.-L.

10.1101/2022.09.08.507071 — bioinformatics — Posted on 2022-09-11

2951 A multiplexed plant-animal SNP array for selective breeding and species conservation applications

Montanari, S.; Deng, C.; Koot, E.; Bassil, N. V.; Zurn, J. D.; Morrison-Whittle, P.; Worthington, M. L.; Aryal, R.; Ashrafi, H.; Pradelles, J.; Wellenreuther, M.; Chagne, D.

10.1101/2022.09.07.507051 — genetics — Posted on 2022-09-11

2952 LIS1, a glyco-humanized swine polyclonal anti-lymphocyte globulin, as a novel induction treatment in solid organ transplantation

Rousse, J.; Royer, P.-J.; Evanno, G.; Lheriteau, E.; Ciron, C.; Salama, A.; Shneiker, F.; Duchi, R.; Perota, A.; Galli, C.; Cozzi, E.; Blancho, G.; Duvaux, O.; Brouard, S.; Soulillou, J.-P.; Bach, J.-M.; Vanhove, B.

10.1101/2022.09.08.507114 — immunology — Posted on 2022-09-11

2953 Lower Aβ-PET signal in white matter lesions relates to higher extracellular free water in mixed small vessel disease and Alzheimer's pathology

Ottoy, J.; Ozzoude, M.; Zukotynski, K.; Kang, M. S.; Adamo, S.; Scott, C.; Ramirez, J.; Swardfager, W.; Lam, B.; Bhan, A.; Mojiri, P.; Kiss, A.; Strother, S.; Bocti, C.; Borrie, M.; Chertkow, H.; Frayne, R.; Hsiung, R.; Laforce, R. J.; Noseworthy, M. D.; Prato, F. S.; Sahlas, D. J.; Smith, E. E.; Kuo, P. H.; Chad, J. A.; Pasternak, O.; Sossi, V.; Thiel, A.; Soucy, J.-P.; Tardif, J.-C.; Black, S. E.; Goubran, M.

10.1101/2021.12.17.473211 — neuroscience — Posted on 2022-09-11

2954 Germplasm Collections and Morphological Studies of Andropogon gayanus-Andropogon tectorum Complex in Southwestern Nigeria

Ojo, F. M.; Nwokeocha, C. C.; Faluyi, J. O.

10.1101/2022.09.10.507395 — plant biology — Posted on 2022-09-11

2955 Development of a new cold hardiness prediction model for grapevine using phased integration of acclimation and deacclimation responses

Kovaleski, A. P.; North, M.; Martinson, T. E.; Londo, J. P.

10.1101/2022.09.09.507298 — plant biology — Posted on 2022-09-11

2956 A small dynamic leaf-level model predicting photosynthesis in greenhouse tomatoes

Joubert, D.; Zhang, N.; Berman, S. R.; Kaiser, E.; Molenaar, J.; Stigter, J. D.

10.1101/2022.09.10.507401 — plant biology — Posted on 2022-09-11

2957 GLKs directly regulate carotenoid biosynthesis via interacting with GBFs in nuclear condensates in plants

Sun, T.; Zeng, S.; Wang, X.; Owens, L.; Fei, Z.; Zhao, Y.; Mazourek, M.; Giovannoni, J. J.; Li, L.

10.1101/2022.09.09.507346 — plant biology — Posted on 2022-09-11

2958 Circadian and environmental signal transduction in a natural population of Arabidopsis

Cano-Ramirez, D. L.; Nishio, H.; Muranaka, T.; de Barros Dantas, L. L.; Honjo, M. N.; Sugisaka, J.; Kudoh, H.; Dodd, A.

10.1101/2022.09.10.507414 — plant biology — Posted on 2022-09-11

2959 Heritable CRISPR-Cas9 editing of plant genomes using RNA virus vectors

Uranga, M.; Aragones, V.; Daros, J.-A.; Pasin, F.

10.1101/2022.09.07.507055 — plant biology — Posted on 2022-09-11

2960 The baseless mutant links protein phosphatase 2A with basal cell identity in the brown alga Ectocarpus

Godfroy, O.; Zheng, M.; Yao, H.; Henschen, A.; Peters, A. F.; Scornet, D.; Colin, S.; Ronchi, P.; Hipp, K.; Nagasato, C.; Motomura, T.; Cock, J. M.; Coelho, S. M.

10.1101/2022.09.10.507423 — developmental biology — Posted on 2022-09-11

2961 Nuclear basket protein ZC3HC1 and its yeast homolog Pml39p feature anevolutionary conserved bimodular construction essential for initial bindingto NPC-anchored homologs of scaffold protein TPR

Gunkel, P.; Iino, H.; Krull, S.; Cordes, V. C.

10.1101/2022.09.10.507405 — cell biology — Posted on 2022-09-10

2962 Rear cortex contraction aids in nuclear transit during confined migration by increasing pressure in the cell posterior

Keys, J. T.; Cheung, B. C. H.; Wu, M.; Lammerding, J.

10.1101/2022.09.10.507419 — cell biology — Posted on 2022-09-10

2963 SPECC1L binds MYPT1/PP1β and can regulate its distribution between microtubules and filamentous actin

Mehta, V.; Decan, N.; Gaudreau-Lapierre, A.; Copeland, J. W.; Trinkle-Mulcahy, L.

10.1101/2022.09.09.507377 — cell biology — Posted on 2022-09-10

2964 Intrinsic and extrinsic inhibition of cortical flow underlies symmetry breaking during unilateral cytokinesis

Hsu, C. R.; Sangha, G.; Fan, W.; Zheng, J.; Sugioka, K.

10.1101/2022.09.09.506560 — cell biology — Posted on 2022-09-10

2965 A small-molecule myosin inhibitor as a targeted multi-stage antimalarial

Trivedi, D. V.; Karabina, A.; Bergnes, G.; Racca, A.; Wander, H.; Jung, S.; Mittal, N.; Huijs, T.; Ouchida, S.; Ruijgrok, P. V.; Song, D.; Wittlin, S.; Mukherjee, P.; Chakraborty, A.; Winzeler, E. A.; Burrows, J. N.; Laleu, B.; Spudich, A.; Ruppel, K.; Dechering, K.; Nag, S.; Spudich, J.

10.1101/2022.09.09.507317 — pharmacology and toxicology — Posted on 2022-09-10

2966 Evolutionary and cellular analysis of the dark pseudokinase PSKH2

Byrne, D. P.; Shrestha, S.; Daly, L. A.; Marensi, V.; Ramakrishnan, K.; Eyers, C. E.; Kannan, N.; Eyers, P. A.

10.1101/2022.09.10.507278 — biochemistry — Posted on 2022-09-10

2967 Cik1 and Vik1 Accessory Proteins Confer Distinct Functions to the Kinesin-14, Kar3

Bergman, Z. J.; Wong, J. J.; Drubin, D.; Barnes, G.

10.1101/2022.09.09.507361 — cell biology — Posted on 2022-09-10

2968 4EBP1/2 support tumorigenicity and cell survival during energetic stress by translationally regulating fatty acid synthesis

Levy, T.; Voeltzke, K.; Hauffe, L.; Alasad, K.; Snaebjornsson, M.; Marciano, R.; Scharov, K.; Planque, M.; Vriens, K.; Christen, S.; Funk, C. M.; Hassiepen, C.; Kahler, A.; Heider, B.; Picard, D.; Lim, J. K.; Bas, Z.; Bendrin, K.; Vargas-Toscano, A.; Kahlert, U.; Remke, M.; Elkabets, M.; Grunewald, T. G.; Reichert, A. S.; Fendt, S.-M. S.; Schulze, A.; Reifenberger, G.; Rotblat, B.; Leprivier, G.

10.1101/2022.09.09.507243 — cell biology — Posted on 2022-09-10

2969 Subcellular distribution of PP1 isoforms in holoenzyme complexes

Mehta, V.; Chamousset, D.; Law, J.; Ooi, S.; Campuzano, D.; Nguyen, V.; Boisvert, F.-M.; Moorhead, G. B.; Trinkle-Mulcahy, L.

10.1101/2022.09.09.507380 — cell biology — Posted on 2022-09-10

2970 Dual role of brain endothelial Gpr126 in blood-brain barrier development and ischemic stroke

Kakogiannos, N.; Scalise, A. A.; Martini, E.; Maderna, C.; Magni, S.; Gullotta, G. S.; Lampugnani, M. G.; Iannelli, F.; Beznusenko, G.; Mironov, A.; Cerutti, C.; Bentley, K.; Philippides, A.; Zanardi, F.; Bacigaluppi, M.; Martino, G.; Dejana, E.; Giannotta, M.

10.1101/2022.09.09.507316 — cell biology — Posted on 2022-09-10

2971 Bone marrow hemogenic endothelial cells contribute multilineage hematopoietic progenitors in adult mice

Feng, J.-X.; Yang, M.-T.; Li, C. C.; Livak, F.; Abdelmaksoud, A.; Wang, D.; Tosato, G.

10.1101/2022.09.09.507292 — cell biology — Posted on 2022-09-10

2972 Stimulating microtubule growth is not the essential function of the microtubule polymerase Stu2

Carrier, J. S.; Torvi, J. R.; Jenson, E.; Jones, C.; Gangadharan, B.; Geyer, E. A.; Rice, L.; Lagesse, B.; Barnes, G.; Miller, M. P.

10.1101/2022.09.09.507218 — cell biology — Posted on 2022-09-10

2973 Acetylation of a fungal effector that translocates host PR1 facilitates virulence

Li, J.; Ma, X.; Wang, C.; Liu, S.; Yu, G.; Gao, M.; Qian, H.; Liu, M.; Luisi, B. F.; Gabriel, D. W.; Liang, W.

10.1101/2022.09.09.507325 — microbiology — Posted on 2022-09-10

2974 A membrane-associated light harvesting model is enabled by functionalized assemblies of gene-doubled TMV proteins

Dai, J.; Wilhelm, K. B.; Bischoff, A. J.; Pereira, J. H.; Dedeo, M. T.; Garcia-Almedina, D. M.; Adams, P. D.; Groves, J. T.; Francis, M. B.

10.1101/2022.09.08.507180 — bioengineering — Posted on 2022-09-10

2975 Silicon as a microfluidic material for imaging and incubation of droplets

Lobato-Dauzier, N.; Deteix, R.; Gines, G.; Baccouche, A.; Hapsianto, B. N.; Okumura, S.; Mariette, G.; Belharet, D.; Queste, S.; Jalabert, L.; Denoual, M.; Rondelez, Y.; Toshiyoshi, H.; Fujita, H.; Kim, S. H.; Fujii, T.; Genot, A. J.

10.1101/2022.09.09.507341 — biochemistry — Posted on 2022-09-10

2976 The mobility of the cap domain is essential for the substrate promiscuity of a family IV esterase from sorghum rhizosphere microbiome

Distaso, M.; Cea-Rama, I.; Coscolin, C.; Chernikova, T. N.; Tran, H.; Ferrer, M.; Sanz-Aparicio, J.; Golyshin, P. N.

10.1101/2022.09.10.507389 — biochemistry — Posted on 2022-09-10

2977 Structural insights into pore dynamics of human Pannexin isoforms

Hussain, N.; Apotikar, A.; Pidathala, S.; Mukherjee, S.; Burada, A. P.; Sikdar, S. K.; Kutti, V. R.; Penmatsa, A.

10.1101/2022.09.09.507385 — biochemistry — Posted on 2022-09-10

2978 A novel overlapping gene azyx-1 affects the translation of zyxin in C. elegans

Parmar, B.; Geens, E.; Vandeweyer, E.; Kieswetter, A.; Ludwig, C.; Temmerman, L.

10.1101/2022.09.09.507294 — genetics — Posted on 2022-09-10

2979 Using machine learning to predict protein-protein interactions between a zombie ant fungus and its carpenter ant host

Will, I.; Beckeson, W. C.; de Bekker, C.

10.1101/2022.09.09.507359 — molecular biology — Posted on 2022-09-10

2980 STAT3 promotes RNA polymerase III-directed transcription by controlling the miR-106a-5p/TP73 axis

Zhang, C.; Zhao, S.; Deng, H.; Zhang, S.; Wang, J.; Song, X.; Yu, D.; Zhang, Y.; Deng, W.

10.1101/2022.09.09.507335 — molecular biology — Posted on 2022-09-10

2981 SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signaling pathway in the absence of VHL

Liu, C.; Li, X.; Zhu, Y.; Fen, W.; Ma, C.; Zhang, W.; Xu, Y.; Gui, L.; Aji, R.; Gao, W.-Q.; Li, L.

10.1101/2022.09.10.507394 — molecular biology — Posted on 2022-09-10

2982 The potent broadly neutralizing antibody VIR-3434 controls Hepatitis B and D Virus infection and reduces HBsAg in humanized mice

Lempp, F. A.; Volz, T.; Cameroni, E.; Benigni, F.; Zhou, J.; Rosen, L. E.; Noack, J.; Zatta, F.; Kaiser, H.; Bianchi, S.; Lombardo, G.; Jaconi, S.; Imam, H.; Soriaga, L. B.; Passini, N.; Belnap, D. M.; Schulze, A.; Luetgehetmann, M.; Telenti, A.; Cathcart, A. L.; Snell, G.; Purcell, L. A.; Hebner, C. M.; Urban, S.; Dandri, M.; Corti, D.; Schmid, M. A.

10.1101/2022.09.09.507326 — microbiology — Posted on 2022-09-10

2983 High evidence targets of conserved plant microRNAs and the complexities of their ancient microRNA binding-sites

Wong, G. Y.; Millar, A. A.

10.1101/2022.09.07.507021 — plant biology — Posted on 2022-09-10

2984 Insights into the activation of Kinesin1 from the molecular characterisation of JIP3/4 binding to Kif5b

Vilela, F.; Chenon, M.; Velours, C.; Andreani, J.; Llinas, P.; Menetrey, J.

10.1101/2022.09.09.507386 — biophysics — Posted on 2022-09-10

2985 Accurate prediction of nucleic acid and protein-nucleic acid complexes using RoseTTAFoldNA

Baek, M.; McHugh, R.; Anishchenko, I.; Baker, D.; DiMaio, F.

10.1101/2022.09.09.507333 — bioinformatics — Posted on 2022-09-10

2986 Sucrose-mediated formation and adhesion strength of Streptococcus mutans biofilms on titanium

Waldman, L. J.; Butera, T.; Boyd, J. D.; Grady, M. E.

10.1101/2022.09.08.507119 — bioengineering — Posted on 2022-09-10

2987 Remodelling of carbon metabolism during sulfoglycolysis in Escherichia coli

Mui, J. W.- Y.; De Souza, D. P.; Saunders, E. C.; McConville, M. J.; Williams, S.

10.1101/2022.09.09.507388 — biochemistry — Posted on 2022-09-10

2988 Intrinsic catalytic properties of histone H3 lysine-9 methyltransferases preserve monomethylation levels under low S-adenosylmethionine

Haws, S. A.; Miller, L. J.; Rojas La Luz, D.; Kuznetsov, V.; Craciun, G.; Denu, J. M.

10.1101/2022.09.09.507378 — biochemistry — Posted on 2022-09-10

2989 Sialidases and Fucosidases of Akkermansia muciniphila are crucial for growth on mucin and nutrient sharing with mucus-associated gut bacteria

Shuoker, B.; Pichler, M. J.; Jin, C.; Sakanaka, H.; Wu, H.; Ana Martinez Gascuena, A.; Liu, J.; Nielsen, T. S.; Holgersson, J.; Nordberg Karlsson, E.; Juge, N.; Meier, S.; Morth, J. P.; Karlsson, N. G.; Abou Hachem, M.

10.1101/2022.09.10.507281 — biochemistry — Posted on 2022-09-10

2990 Olfactory responses of Drosophila suzukii parasitoids to chemical cues from SWD-infested

Trinanes, F.; Gonzalez Ritzel, A.; de la vega, G. J.

10.1101/2022.09.08.507209 — animal behavior and cognition — Posted on 2022-09-10

2991 DipM controls multiple autolysins and mediates two regulatory feedback loops promoting cell constriction in C. crescentus

Izquierdo-Martinez, A.; Miguel-Ruano, V.; Hernandez-Tamayo, R.; Biboy, J.; Batuecas, M. T.; Billini, M.; Glatter, T.; Vollmer, W.; Graumann, P. L.; Hermoso, J. A.; Thanbichler, M.

10.1101/2022.09.10.507391 — microbiology — Posted on 2022-09-10

2992 An unwanted association: the threat to papaya crops by a novel potexvirus in northwest Argentina

Cabrera Mederos, D.; Debat, H. J.; Torres, C.; Portal, O.; Jaramillo Zapata, M.; Trucco, V.; Flores, C.; Ortiz, C.; Badaracco, A.; Acuna, L.; Nome, C.; Quito-Avila, D.; Bejerman, N.; Castellanos Collazo, O.; Sanchez-Rodriguez, A.; Giolitti, F.

10.1101/2022.09.09.507323 — microbiology — Posted on 2022-09-10

2993 Developmental role of macrophages modelled in human pluripotent stem cell derived intestinal tissue

Andelfinger, G.; Song, A.; Sindeaux, R. H. M.; Li, Y.; Affia, H.; Agnihotri, T.; Leclerc, S.; van Vliet, P. P.; Colas, M.; Guimond, J.-V.; Patey, N.; Joyal, J.-S.; Haddad, E.; Barreiro, L.

10.1101/2022.09.09.505715 — developmental biology — Posted on 2022-09-10

2994 PI 4-kinases promote cell surface expansion and facilitate tissue morphogenesis during Drosophila cellularization and gastrulation

Chen, W.; Bergstein, V.; He, B.

10.1101/2022.09.09.507384 — developmental biology — Posted on 2022-09-10

2995 Heterogeneous migration of neuronal progenitors to the insula shapes the human brain

Mallela, A. N.; Deng, H.; Gholipour, A.; Warfield, S. K.; Goldschmidt, E.

10.1101/2022.09.09.507371 — developmental biology — Posted on 2022-09-10

2996 Thyroid Ablation Alters Passive Stiffness and Swimming Kinematics in Zebrafish

Parikh, P.; Nguyen, S.; McMenamin, S.; Kenaley, C.

10.1101/2022.09.09.507357 — developmental biology — Posted on 2022-09-10

2997 The imprinted Mir483 is a growth suppressor and metabolic regulator functioning through IGF1

Sandovici, I.; Fernandez-Twinn, D. S.; Campbell, N.; Cooper, W. N.; Sekita, Y.; Zvetkova, I.; Ferland-McCollough, D.; Prosser, H. M.; Oyama, L. M.; Cimadomo, D.; de Queiroz, K. B.; Cheuk, C. S. K.; Smith, N. M.; Kay, R. G.; Hoelle, K.; Smith, N. H.; Geyer, S. H.; Reissig, L. F.; Weninger, W. J.; Siddle, K.; Willis, A. E.; Bushell, M.; Ozanne, S. E.; Constancia, M.

10.1101/2022.09.09.507324 — developmental biology — Posted on 2022-09-10

2998 How short decoding times, stimulus dimensionality and spontaneous activity constrain the shape of tuning curves: A speed-accuracy trade-off

Lenninger, M.; Skoglund, M.; Herman, P. A.; Kumar, A.

10.1101/2022.09.09.505677 — neuroscience — Posted on 2022-09-10

2999 A Programmable Model for Exploring the Functional Logic of the Drosophila Mushroom Body

Lazar, A. A.; Turkcan, M. K.; Zhou, Y.

10.1101/2022.09.10.506218 — neuroscience — Posted on 2022-09-10

3000 Comparison of visual quantities in untrained deep neural networks

Lee, H.; Choi, W.; Lee, D.; Paik, S.-B.

10.1101/2022.09.08.507097 — neuroscience — Posted on 2022-09-10

3001 The effects of acute Methylene Blue administration on cerebral blood flow and metabolism in humans and rats

Singh, N.; MacNicol, E.; DiPasquale, O.; Randall, K. L.; Ndabezinhle, M.; Simmons, C.; Selvaggi, P.; Stephenson, S.; Turkheimer, F. E.; Cash, D.; Zelaya, F.; Colasanti, A.

10.1101/2022.09.10.507418 — neuroscience — Posted on 2022-09-10

3002 Transcription and DNA methylation signatures of paternal care in hippocampal dentate gyrus of prairie voles

Waddell, N. J.; Liu, Y.; Chitaman, J. M.; Kaplan, G. J.; Wang, Z.; Feng, J.

10.1101/2022.09.09.507382 — neuroscience — Posted on 2022-09-10

3003 Localizing the Sources of Modulations of the P3m Component by Task Difficulty

Boetzel, C.; Kasten, F. H.; Herrmann, C. S.

10.1101/2022.09.09.507266 — neuroscience — Posted on 2022-09-10

3004 G protein-coupled Receptor Contributions to Wing Growth and Morphogenesis in Drosophila melanogaster

Huizar, F. J.; Kumar, N.; Unger, M.; Velagala, V.; Wu, Q.; Brodskiy, P. A.; Zartman, J. J.

10.1101/2022.09.09.506847 — developmental biology — Posted on 2022-09-10

3005 FGF signaling regulates salivary gland branching morphogenesis by modulating cell adhesion

Ray, A. T.; Soriano, P.

10.1101/2022.09.10.507412 — developmental biology — Posted on 2022-09-10

3006 How enhancers regulate wavelike gene expression patterns: A novel enhancer prediction and live reporter system identifies an enhancer associated with the arrest of pair-rule waves in Tribolium

Mau, C.; Rudolf, H.; Strobl, F.; Schmid, B.; Regensburger, T.; Palmisano, R.; Stelzer, E.; Taher, L.; El-Sherif, E.

10.1101/2022.09.09.507237 — developmental biology — Posted on 2022-09-10

3007 ATFS-1 regulates peroxisome assembly genes and protects both mitochondria and peroxisomes during peroxin perturbations

Shpilka, T.; Uma Naresh, N.; Du, Y.; Watts, J. L.; Haynes, C. M.

10.1101/2022.09.09.507280 — developmental biology — Posted on 2022-09-10

3008 X-linked adrenoleukodystrophy patient fibroblast-iPSC-derived astrocytes reveal phenotype-specific metabolic, inflammatory, and microRNA alterations

PARASAR, P.; Kaur, N.; Poisson, L.; Singh, J.

10.1101/2022.09.09.507263 — neuroscience — Posted on 2022-09-10

3009 Probing visual sensitivity and attention in mice using reverse correlation

Lehnert, J.; Cha, K.; Yang, K.; Zheng, D. F.; Khadra, A.; Cook, E.; Krishnaswamy, A.

10.1101/2022.09.08.507101 — neuroscience — Posted on 2022-09-10

3010 Quantitative comparison of CRISPR-Cas9-mediated mutation efficiency between mice and MEFs using digital PCR assays

Lee, K.; Lee, C.

10.1101/2022.09.09.507282 — neuroscience — Posted on 2022-09-10

3011 Resting fMRI-guided TMS evokes subgenual anterior cingulate response in depression

Duprat, R. J.; Linn, K. A.; Satterthwaite, T. D.; Sheline, Y. I.; Liang, X.; Bagdon, G.; Flounders, M. W.; Robinson, H.; Platt, M.; Kable, J.; Long, H.; Scully, M.; Deluisi, J. A.; Thase, M.; Cristancho, M.; Reber, J.; Shinohara, R. T.; Oathes, D.

10.1101/2022.09.08.507012 — neuroscience — Posted on 2022-09-10

3012 Extensive Soma-Soma Plate-Like Contact Sites (Ephapses) Connect Suprachiasmatic Nucleus Neurons

Czeisler, M. E.; Shan, Y.; Schalek, R. L.; Berger, D. R.; Suissa-Peleg, A.; Takahashi, J. S.; Lichtman, J. W.

10.1101/2022.09.09.507192 — neuroscience — Posted on 2022-09-10

3013 Low noise HRTFs and delay line corrections are detrimental to the prediction of ITD discrimination thresholds from environmental statistics

Camperos, M. J. G.; Goncalves, T. C.; Marin, B.; Pavao, R.

10.1101/2022.09.09.507313 — neuroscience — Posted on 2022-09-10

3014 The BigMac dataset: an open resource combining multi-contrast MRI and microscopy in the macaque brain

Howard, A. F.; Huszar, I. N.; Smart, A.; Cottaar, M.; Daubney, G.; Hanayik, T.; Khrapitchev, A. A.; Mars, R. B.; Mollink, J.; Scott, C.; Sibson, N. R.; Sallet, J.; Jbabdi, S.; Miller, K. L.

10.1101/2022.09.08.506363 — neuroscience — Posted on 2022-09-10

3015 Death induced by survival gene elimination (DISE) contributes to neurotoxicity in Alzheimer's disease

Paudel, B.; Jeong, S.-Y.; Martinez, C. P.; Rickman, A.; Haluck-Kangas, A.; Bartom, E. T.; Frederiksen, K.; Affaneh, A.; Kessler, J. A.; Mazzulli, J. R.; Murmann, A. E.; Rogalski, E.; Geula, C.; Ferreira, A.; Heckmann, B. L.; Green, D. R.; Sadleir, K. R.; Vassar, R.; Peter, M. E.

10.1101/2022.09.08.507157 — neuroscience — Posted on 2022-09-10

3016 Proactive interhemispheric disinhibition supports response preparation during selective stopping

Wadsley, C. G.; Cirillo, J.; Nieuwenhuys, A.; Byblow, W. D.

10.1101/2022.09.08.507205 — neuroscience — Posted on 2022-09-10

3017 Characterizing the differential distribution and targets of Sumo paralogs in the mouse brain

Suk, T. R.; Nguyen, T. T.; Fisk, Z. A.; Mitkovski, M.; Geertsma, H. M.; Parmasad, J.-L. A.; Heer, M. M.; Callaghan, S. M.; Brose, N.; Tirard, M.; Rousseaux, M. W. C.

10.1101/2022.09.09.507035 — neuroscience — Posted on 2022-09-10

3018 Examining Litter Specific Variability in Mice and its Impact on Neurodevelopmental Studies

Valiquette, V.; Guma, E.; Cupo, L.; Gallino, D.; Anastassiadis, C.; Snook, E.; Devenyi, G. A.; Chakravarty, M. M.

10.1101/2022.09.09.506402 — neuroscience — Posted on 2022-09-10

3019 Two Synaptic Convergence Motifs Define Functional Roles for Inputs to Cochlear Nucleus Bushy Cells

Spirou, G. A.; Kersting, M.; Carr, S.; Razzaq, B.; Alves-Pinto, C. Y.; Dawson, M.; Ellisman, M. H.; Manis, P. B.

10.1101/2022.09.10.507000 — neuroscience — Posted on 2022-09-10

3020 Neuronal mitochondrial morphology is significantly affected by both fixative and oxygen level during perfusion

Kim, S. Y.; Strucinska, K.; Osei, B.; Han, K.; Kwon, S.-K.; Lewis, T. L.

10.1101/2022.09.08.507147 — neuroscience — Posted on 2022-09-10

3021 Individual variability in neural event segmentation reflects stimulus content and interpretation

Sava-Segal, C.; Richards, C.; Leung, M.; Finn, E. S.

10.1101/2022.09.09.507003 — neuroscience — Posted on 2022-09-10

3022 Young adults use whole-body feedback to perceive small locomotor disturbances.

Liss, D. J.; Carey, H. D.; Allen, J.

10.1101/2022.09.08.507184 — neuroscience — Posted on 2022-09-10

3023 Does Functional Recovery Imply Stable Circuitry in the Spinal Animal?

Refy, O.; Geyer, H.

10.1101/2022.09.09.507338 — neuroscience — Posted on 2022-09-10

3024 Beta spectral power during sleep is associated with impaired recall of extinguished fear

Denis, D.; Bottary, R.; Cunningham, T. J.; Drummond, S. P. A.; Straus, L. D.

10.1101/2022.09.08.506006 — neuroscience — Posted on 2022-09-10

3025 Characterizing Cone Spectral Classification by Optoretinography

Pandiyan, V. P.; Schleufer, S.; Slezak, E.; Fong, J.; Upadhyay, R.; Roorda, A.; Ng, R.; Sabesan, R.

10.1101/2022.09.07.507027 — neuroscience — Posted on 2022-09-10

3026 Selective inhibition of excitatory synaptic transmission alters the emergent bursting dynamics of in vitro neural networks

Weir, J. S.; Christiansen, N.; Sandvig, A.; Sandvig, I.

10.1101/2022.09.08.507095 — neuroscience — Posted on 2022-09-10

3027 Invariance of object detection in untrained deep neural networks

Cheon, J.; Baek, S.; Paik, S.-B.

10.1101/2022.09.08.507096 — neuroscience — Posted on 2022-09-10

3028 RoboEM: automated 3D flight tracing for synaptic-resolution connectomics

Schmidt, M.; Motta, A.; Sievers, M.; Helmstaedter, M.

10.1101/2022.09.08.507122 — neuroscience — Posted on 2022-09-10

3029 Activity in primate visual cortex is minimally driven by spontaneous movements

Thalluri, B. C.; Kang, I.; Lazere, A.; Quinn, K. R.; Kaliss, N.; Yates, J.; Butts, D. A.; Nienborg, H.

10.1101/2022.09.08.507006 — neuroscience — Posted on 2022-09-10

3030 Single-Cell Transcriptomic Profiling of the Zebrafish Inner Ear Reveals Molecularly Distinct Hair Cell and Supporting Cell Subtypes

Shi, T.; Beaulieu, M. O.; Saunders, L. M.; Fabian, P.; Trapnell, C.; Segil, N.; Crump, J. G.; Raible, D. W.

10.1101/2022.09.08.507120 — neuroscience — Posted on 2022-09-10

3031 Successful working memory linked to theta connectivity patterns in the hippocampal-entorhinal circuit

Li, J.; Cao, D.; Yu, S.; Wang, H.; Imbach, L.; Stieglitz, L.; Sarnthein, J.; Jiang, T.

10.1101/2022.09.08.507081 — neuroscience — Posted on 2022-09-10

3032 Postsynaptic receptors regulate presynaptic neurotransmitter stability

Godavarthi, S. K.; Hiramoto, M.; Ignatyev, Y.; Levin, J. B.; Li, H.; Pratelli, M.; Borchardt, J.; Czajkowski, C. M.; Borodinsky, L. N.; Sweeney, L.; Cline, H. T.; Spitzer, N. C.

10.1101/2022.09.10.507343 — neuroscience — Posted on 2022-09-10

3033 Associations between methylation age and brain age in late adolescence

Sanders, F.; Baltramonaityte, V.; Donohoe, G.; Davies, N. M.; Dunn, E. C.; Cecil, C. A. M.; Walton, E.

10.1101/2022.09.08.506972 — neuroscience — Posted on 2022-09-10

3034 Histone deacetylase 3 regulates microglial function through histone deacetylation

Meleady, L.; Towris, M.; Bacarac, V.; Kim, J.; Rowland, M.; Ciernia, A. V.

10.1101/2022.09.08.507183 — neuroscience — Posted on 2022-09-10

3035 Intrinsic reward-like dopamine and acetylcholine dynamics in striatum

Krok, A. C.; Mistry, P.; Li, Y.; Tritsch, N. X.

10.1101/2022.09.09.507300 — neuroscience — Posted on 2022-09-10

3036 Dynamic fluctuations in ascending heart-to-brain modulations under mental stress elicitation

Candia-Rivera, D.; Norouzi, K.; Ramsoy, T. Z.; Valenza, G.

10.1101/2022.09.09.507362 — neuroscience — Posted on 2022-09-10

3037 Mapping the glial transcriptome in Huntington's disease using snRNAseq: Selective disruption of glial signatures across brain regions

Boestrand, S. M. K.; Seeker, L. A.; Kazakou, N.-L.; Bestard-Cuche, N.; Jaekel, S.; Kenkhuis, B.; Henderson, N. C.; de Bot, S. T.; van Roon-Mom, W.; Priller, J.; Williams, A.

10.1101/2022.09.10.507291 — neuroscience — Posted on 2022-09-10

3038 Local and long-distance inputs dynamically regulate striatal acetylcholine during decision making

Chantranupong, L.; Beron, C. C.; Zimmer, J. A.; Wen, M. J.; Wang, W.; Sabatini, B. L.

10.1101/2022.09.09.507130 — neuroscience — Posted on 2022-09-10

3039 Spectral slope and neural complexity as robust markers of task demand and brain state during sleep and wakefulness

Höhn, C.; Hahn, M. A.; Lendner, J. D.; Hoedlmoser, K.

10.1101/2022.09.10.507390 — neuroscience — Posted on 2022-09-10

3040 Synchronous multi-segmental activity between metachronal waves controls locomotion speed in Drosophila larvae

Liu, Y.; Hasegawa, E.; Nose, A.; Zwart, M. F.; Kohsaka, H.

10.1101/2022.09.08.507222 — neuroscience — Posted on 2022-09-10

3041 Attenuation of neural responses in subthalamic nucleus during internally guided voluntary movements in Parkinson's disease

Filyushkina, V.; Belova, E.; Usova, S.; Tomskiy, A.; Sedov, A.

10.1101/2022.09.09.507256 — neuroscience — Posted on 2022-09-10

3042 Unsupervised Restoration of a Complex Learned Behavior After Large-Scale Neuronal Perturbation

Wang, B.; Torok, Z.; Duffy, A.; Bell, D.; Wongso, S.; Velho, T.; Fairhall, A.; Lois, C.

10.1101/2022.09.09.507372 — neuroscience — Posted on 2022-09-10

3043 Biologically relevant integration of transcriptomics profiles from cancer cell lines, patient-derived xenografts and clinical tumors using deep learning

Dimitrieva, S.; Janssens, R.; Li, G.; Szalata, A.; Gopal, R.; Parmar, C.; Kauffmann, A.; Durand, E. Y.

10.1101/2022.09.07.506964 — bioinformatics — Posted on 2022-09-10

3044 Investigating microglia-neuron crosstalk by characterizing microglial contamination in human and mouse Patch-seq datasets

Arbabi, K.; Jiang, Y.; Howard, D.; Inoue, W.; Gonzalez-Burgos, G.; Felsky, D.; Tripathy, S. J.

10.1101/2022.09.07.507009 — neuroscience — Posted on 2022-09-10

3045 The evolution of host resistance to a virus is determined by resources, historical contingency, and time scale

Visher, E.; Mahjoub, H.; Soufi, K.; Pascual, N.; Hoang, V.; Bartlett, L. J.; Roberts, K. E.; Meaden, S.; Boots, M.

10.1101/2022.09.08.507185 — evolutionary biology — Posted on 2022-09-10

3046 In-silico comparative modeling and interaction studies of PRSV proteins - Accelerated towards dissection of structure based evolutionary divergence and functional interaction of virus within the host

Saleem, A.; Ali, Z.; Naseem, S.

10.1101/2022.09.09.507246 — evolutionary biology — Posted on 2022-09-10

3047 Variation in morphology among populations of threespine stickleback (Gasterosteus aculeatus) from western Newfoundland, Canada.

Scott, R. J.; Haines, G. E.; Biedak, N. R.; Baker, J. A.

10.1101/2022.09.08.507156 — evolutionary biology — Posted on 2022-09-10

3048 Ribosomes as molecular thermometers: metal-binding sites in ribosomal proteins are robust indicators of bacterial adaptation to heat and cold

van den Elzen, A.; Helena-Bueno, K.; Brown, C. R.; Melnikov, S. V.

10.1101/2022.09.09.507293 — evolutionary biology — Posted on 2022-09-10

3049 Evolutionary dynamics of dengue virus in India

Jagtap, S.; Pattabiraman, C.; Sankaradoss, A.; Krishna, S.; Roy, R.

10.1101/2022.09.08.507083 — evolutionary biology — Posted on 2022-09-10

3050 HexSE: Simulating evolution in overlapping reading frames

Munoz-Baena, L.; Wade, K.; Poon, A.

10.1101/2022.09.09.453067 — bioinformatics — Posted on 2022-09-10

3051 Changes in global repression underlie the evolution of Drosophila abdominal pigmentation

Mendez-Gonzalez, I. D.; Williams, T. M.; Rebeiz, M.

10.1101/2022.09.09.507277 — evolutionary biology — Posted on 2022-09-10

3052 Fitness of a clonal population can be inferred from lineage trees without knowledge of the biological details

Escabi, J.; Hormoz, S.

10.1101/2022.09.09.507320 — evolutionary biology — Posted on 2022-09-10

3053 When good species have porous boundaries: weak reproductive isolation and extensive gene flow between Mimulus glaucescens and M. guttatus in northern California

Coughlan, J. M.; Habecker, N.; Bergmann, J. P.; Ewald, J.; Ivey, C.

10.1101/2022.09.08.507212 — evolutionary biology — Posted on 2022-09-10

3054 Parallel genomic basis of age at maturity across spatial scales in Atlantic Salmon

Kess, T.; Lehnert, S. J.; Bentzen, P.; Duffy, S.; Messmer, A.; Dempson, J. B.; Newport, J.; Whidden, C.; Robertson, M. J.; Chaput, G.; Breau, C.; April, J.; Gillis, C.-A.; Kent, M. P.; Nugent, C.; Bradbury, I. R.

10.1101/2022.09.09.507321 — evolutionary biology — Posted on 2022-09-10

3055 Effects of Familial Alzheimer's Disease Mutations on the Folding Free Energy and Dipole-Dipole Interactions of the Amyloid β-Peptide

Davidson, D. S.; Kraus, J. A.; Montgomery, J. M.; Lemkul, J.

10.1101/2022.05.19.492750 — biophysics — Posted on 2022-09-10

3056 The crisprVerse: a comprehensive Bioconductor ecosystem for the design of CRISPR guide RNAs across nucleases and technologies

Hoberecht, L.; Perampalam, P.; Lun, A.; Fortin, J.-P.

10.1101/2022.04.21.488824 — bioinformatics — Posted on 2022-09-10

3057 Mutators drive evolution of multi-resistance to antibiotics

Gifford, D. R.; Berrios-Caro, E.; Joerres, C.; Sune, M.; Forsyth, J.; Bhattacharyya, A.; Galla, T.; Knight, C. G.

10.1101/643585 — evolutionary biology — Posted on 2022-09-10

3058 Genome-wide association studies reveal distinct genetic correlates and increased heritability of antimicrobial resistance in Vibrio cholerae under anaerobic conditions

Creasy-Marrazzo, A.; Saber, M. M.; Kamat, M.; Bailey, L. S.; Brinkley, L. M.; Cato, E. T.; Begum, Y. A.; Rashid, M. M.; Khan, A. I.; Qadri, F.; Basso, K. B.; Shapiro, B. J.; Nelson, E. J.

10.1101/2021.06.26.450051 — microbiology — Posted on 2022-09-10

3059 Commensal bacteria promote type I interferon signaling to maintain immune tolerance

Vasquez Ayala, A.; Hsu, C.-Y.; Matsuo, K.; Buzun, E.; Carrillo Terrazas, M.; Loomis, L. R.; Lu, H.-H.; Park, J.-H.; Rivaud, P.; Thomson, M.; Chu, H.

10.1101/2021.10.21.464743 — immunology — Posted on 2022-09-10

3060 Conduction Velocities of Excitatory Axons Innervating Parvalbumin Interneurons in Primary Somatosensory Cortex

Scheuer, K. S.; Zhao, X.; Jackson, M. B.

10.1101/2022.07.27.501767 — neuroscience — Posted on 2022-09-10

3061 HCN1 channels mediate mu opioid receptor long-term depression at insular cortex inputs to the dorsal striatum

Munoz, B.; Fritz, B. M.; Yin, F.; Atwood, B. K.

10.1101/2021.08.31.458358 — neuroscience — Posted on 2022-09-10

3062 Community interactions drive the evolution of antibiotic tolerance in bacteria

Pearl Mizrahi, S.; Goyal, A.; Gore, J.

10.1101/2022.06.02.494585 — evolutionary biology — Posted on 2022-09-10

3063 Brain Volumes, Thicknesses, and Surface Areas as Mediators of Genetic Factors and Childhood Adversity on Intelligence

Williams, C. M.; Peyre, H.; Ramus, F.

10.1101/2022.09.08.507068 — neuroscience — Posted on 2022-09-10

3064 Your turn, my turn. Neural synchrony in mother-infant proto-conversation.

Nguyen, T.; Zimmer, L.; Hoehl, S.

10.1101/2022.09.09.507239 — neuroscience — Posted on 2022-09-10

3065 Frontotemporal network engagement by human intracranial stimulation in limbic hubs

Allawala, A. B.; Bijanki, K. R.; Oswalt, D.; Mathura, R.; Adkinson, J.; Pirtle, V.; Metzger, B.; Shofty, B.; Robinson, M. E.; Anand, A.; Najera, R. A.; Gadot, R.; Harrison, M. T.; Mathew, S. J.; Goodman, W. K.; Pouratian, N.; Sheth, S.; Borton, D. A.

10.1101/2022.09.08.507155 — neuroscience — Posted on 2022-09-10

3066 Optogenetic induction of chronic glucocorticoid exposure in early-life impairs stress-response in larval zebrafish.

Nagpal, J.; Eachus, H.; Lityagina, O.; Ryu, S.

10.1101/2022.09.09.507267 — neuroscience — Posted on 2022-09-10

3067 Anterior hypothalamic parvalbumin neurons are glutamatergic and promote escape behavior

Laing, B. T.; Anderson, M. S.; Bonventura, J.; Jayan, A.; Sarsfield, S.; Gajendiran, A.; Michaelides, M.; Aponte, Y.

10.1101/2022.09.09.507287 — neuroscience — Posted on 2022-09-10

3068 Identification of regulatory elements in primary sensory neurons involved in neuropathic pain

Stephens, K. E.; Moore, C.; Vinson, D. A.; White, B. E.; Renfro, Z.; Zhou, W. E.; Ji, Z.; Ji, H.; Zhu, H.; Guan, Y.; Taverna, S.

10.1101/2022.09.09.507328 — neuroscience — Posted on 2022-09-10

3069 In silico, biochemical, and in vitro analysis of silvestrol binding to the DEAD box RNA helicase eIF4A reveals broad anti-pathogen potential of rocaglates across the eukaryotic tree of life

Obermann, W.; Azri, M. F. D. B.; Konopka, L.; Schmidt, N.; Magari, F.; Sherman, J.; Silva, L. M. R.; Hermosilla, C.; Ludewig, A. H.; Houhou, H.; Haberlaein, S.; Luo, M. Y.; Häcker, I.; Schetelig, M. F.; Grevelding, C. G.; Schroeder, F. C.; Lau, G.; Taubert, A.; Rodriguez, A.; Heine, A.; Yeo, T. C.; Grünweller, A.; Taroncher-Oldenburg, G.

10.1101/2022.09.09.507249 — molecular biology — Posted on 2022-09-10

3070 A systematic review and comparison of automated tools for quantification of fibrous networks

de Vries, J. J.; Laan, D.; Frey, F.; Koenderink, G. H.; de Maat, M. P. M.

10.1101/2022.09.08.507154 — molecular biology — Posted on 2022-09-10

3071 Molecular mechanism of substrate recognition by folate transporter SLC19A1

Dang, Y.; Zhou, D.; Du, X.; Zhao, H.; Lee, C.-H.; Yang, J.; Qin, C.; Guo, Z.; Zhang, Z.

10.1101/2022.09.09.507238 — biochemistry — Posted on 2022-09-10

3072 Tethered agonist activated ADGRF1 structure reveals molecular preference for Gq signaling

Jones, D. T. D.; Blacklow, S. C.; Dates, A. N.; Burruss, M. M.; Lipper, C. H.; Rawson, S. D.

10.1101/2022.09.09.507336 — biochemistry — Posted on 2022-09-10

3073 Comparative analysis of CRISPR off-target activity discovery tools following ex vivo editing of CD34+ hematopoietic stem and progenitor cells

Cromer, M. K.; Majeti, K. R.; Rettig, G. R.; Murugan, K.; Kurgan, G. L.; Hampton, J. P.; Vakulskas, C. A.; Behlke, M. A.; Porteus, M. H.

10.1101/2022.09.09.507306 — genomics — Posted on 2022-09-10

3074 Expression profiling of immune-response-genes common in SARS-CoV-1 and influenza A virus disease, viz-a-viz neutropenia disorder, using integrated bioinformatics tools

Olaniyi, A. C.; Oluwadamilola, O. D.; Oluwabunmi, A. T.

10.1101/2022.09.09.507303 — genetics — Posted on 2022-09-10

3075 Mechanism of small molecule inhibition of Plasmodium falciparum myosin A informs antimalarial drug design

Moussaoui, D.; Robblee, J. P.; Auguin, D.; Fisher, F.; Fagnant, P. M.; MacFarlane, J. E.; Schaletzky, J.; Wehri, E.; Mueller-Dieckmann, C.; Baum, J.; Robert-Paganin, J.; Trybus, K.; Houdusse, A.

10.1101/2022.09.09.507123 — molecular biology — Posted on 2022-09-09

3076 Transcriptome-wide characterization of piRNAs during the developmental process of European honey bee larval guts

Xu, Y.; Long, Q.; Fan, X.; Ye, Y.; Zhang, K.; Zhang, J.; Zhao, H.; Yao, Y.; Ji, T.; Lin, Z.; Fu, Z.; Chen, D.; Guo, R.

10.1101/2022.09.08.507214 — molecular biology — Posted on 2022-09-09

3077 The protein phosphatases MoPtc1 and MoPtc2 are induced during pathogen-host interactions and play synergistic roles in regulating MAPK pathways in Magnaporthe oryzae

Anjago, W. M.; Biregeya, J.; Mingyue, S.; Yupeng, W.; Yixiao, C.; ARON, O.; Norvienyeku, J.; Chen, M.; Yu, W.; Wang, Z.; Zhang, D.

10.1101/2022.09.09.507255 — molecular biology — Posted on 2022-09-10

3078 Experimental and theoretical aspects of Golden Gate Assembly assays

Strzelecki, P.; Shpiruk, A.; Hoffmann, E.; Cech, G. M.; Kloska, A.; Hebraud, P.; Beyer, N.; Busi, F.; Grange, W.

10.1101/2022.09.09.507109 — molecular biology — Posted on 2022-09-10

3079 Genomic features predict bacterial life history strategies in soil, as identified by metagenomic stable isotope probing

Barnett, S. E.; Egan, R.; Foster, B.; Eloe-Fadrosh, E. A.; Buckley, D. H.

10.1101/2022.09.09.507310 — microbiology — Posted on 2022-09-09

3080 Staphyloxanthin production by Staphylococcus aureus promotes resistance to oxidative stress to delay diabetic wound healing

McCready-Vangi, A. R.; Campbell, A. E.; Uberoi, A.; Lovins, V. M.; White, E. K.; Morgenstern, A. R.; Gardner, S. E.; Grice, E. A.

10.1101/2022.09.09.507290 — microbiology — Posted on 2022-09-09

3081 Metataxonomic insights in the distribution of Lactobacillaceae in foods and food environments

Parente, E.; Zotta, T.; Giavalisco, M.; Ricciardi, A.

10.1101/2022.09.09.507241 — microbiology — Posted on 2022-09-09

3082 Identification of KNX-002, a novel inhibitor of Toxoplasma motility targeting the Class XIV myosin, TgMyoA

Kelsen, A.; Kent, R. S.; Snyder, A. K.; Wehri, E.; Bishop, S. J.; Stadler, R. V.; Powell, C.; Rompikuntal, P. K.; Boulanger, M. J.; Warshaw, D. M.; Westwood, N. J.; Schaletzky, J.; Ward, G. E.

10.1101/2022.09.09.507210 — microbiology — Posted on 2022-09-09

3083 Environmental selection influences the microbiome of subsurface petroleum reservoirs

Gittins, D. A.; Bhatnagar, S.; Hubert, C. R. J.

10.1101/2022.09.08.507151 — microbiology — Posted on 2022-09-09

3084 Endogenous Plasmids and Reductive Genome Evolution in Host-Associated Bacteria

XIONG, Q.; Fung, C. S.-H.; Xiao, X.; Wan, A. T.-Y.; Wang, M.; Ren, Y.; Yang, K. Y.; Cui, Y.; Liu, X.; Tsui, S. K.-W.

10.1101/2022.09.09.507235 — microbiology — Posted on 2022-09-10

3085 A new and highly effective method for predicting T-cell response targets implemented on SARS-CoV-2 data

Flegr, J.; Zahradnik, D.

10.1101/2022.09.09.507307 — immunology — Posted on 2022-09-09

3086 Gibson Assembly-based direct cloning of plasmid DNA in Lactiplantibacillus plantarum WCSF1

Blanch Asensio, M.; Dey, S.; Sankaran, S.

10.1101/2022.09.09.507304 — synthetic biology — Posted on 2022-09-09

3087 SARS-CoV-2 polyprotein substrate regulates the stepwise Mpro cleavage reaction

Narwal, M.; Armache, J.-P.; Edwards, T.; Murakami, K. S.

10.1101/2022.09.09.507133 — biophysics — Posted on 2022-09-09

3088 Phylogeny-aware linear B-cell epitope predictor detects candidate targets for specific immune responses to Monkeypox virus

Campelo, F.; Reis-Cunha, J. L.; Ashford, J.; Ekart, A.; Lobo, F.

10.1101/2022.09.08.507179 — bioinformatics — Posted on 2022-09-09

3089 A novel biopolymer for mucosal adjuvant against respiratory pathogens

Hoover, A. R.; More, S.; Liu, K.; West, C. L.; Valerio, T. I.; Yu, N.; Villalva, C.; Kumar, A.; Alleruzzo, L.; Lam, S. S. K.; Hode, T.; Papin, J. F.; Chen, W. R.

10.1101/2022.09.07.506979 — bioengineering — Posted on 2022-09-09

3090 Conserved intramolecular networks in GDAP1 are closely connected to CMT-linked mutations and protein stability

Sutinen, A.; Paffenholz, D.; Nguyen, G. T. T.; Ruskamo, S.; Torda, A. E.; Kursula, P.

10.1101/2022.09.09.507262 — biochemistry — Posted on 2022-09-09

3091 A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability

Podgorski, J. M.; Freeman, K.; Gosselin, S.; Huet, A.; Conway, J. F.; Bird, M.; Grecco, J.; Patel, S.; Jacobs-Sera, D.; Hatfull, G.; Gogarten, J. P.; Ravantti, J.; White, S. J.

10.1101/2022.09.09.507160 — biochemistry — Posted on 2022-09-09

3092 High-resolution structures map the metal import pathway in an Nramp transporter

Ray, S.; Berry, S. P.; Wilson, E. A.; Zhang, C. H.; Shekhar, M.; Singharoy, A.; Gaudet, R.

10.1101/2022.09.08.507188 — biochemistry — Posted on 2022-09-09

3093 Characterization of p38a signaling networks in cancer cells using quantitative proteomics and phosphoproteomics

Dan, Y.; Radic, N.; Gay, M.; Fernandez, A.; Arauz, G.; Vilaseca, M.; Aloy, P.; Canovas, B.; Nebreda, A. R.

10.1101/2022.09.09.507259 — biochemistry — Posted on 2022-09-09

3094 Cellular stress modulates severity of the acute respiratory distress syndrome in COVID-19

Rico-Llanos, G.; Porras, O.; Escalante, S.; Vazquez, D.; Valiente, L.; Castillo, M.; Perez-Tejeiro, J. M.; Baglietto, D.; Becerra, J.; Reguera, J. M.; Duran, I.; Csukasi, F.

10.1101/2022.09.09.507257 — cell biology — Posted on 2022-09-09

3095 Serum-dependent recruitment of the chromatin remodeler CHD8 to promoters is mediated by the ERK-ELK pathway

Reyes, J. C.; Subtil-Rodriguez, A.; Vazquez-Chavez, E.; Guerrero-Martinez, J. A.; Ceballos-Chavez, M.

10.1101/2022.09.09.507301 — molecular biology — Posted on 2022-09-09

3096 Bacterial Argonaute nucleases reveal different modes of DNA targeting in vitro and in vivo

Lisitskaya, L.; Kropocheva, E.; Agapov, A.; Prostova, M.; Panteleev, V.; Yudin, D.; Ryazansky, S.; Kuzmenko, A.; Aravin, A.; Esyunina, D.; Kulbachiskiy, A.

10.1101/2022.09.09.507302 — molecular biology — Posted on 2022-09-09

3097 CP204L Is a Multifunctional Protein of African Swine Fever Virus That Interacts with The VPS39 Subunit of HOPS Complex and Promotes Lysosome Clustering

Dolata, K. M.; Fuchs, W.; Caignard, G.; Dupre, J.; Pannhorst, K.; Blome, S.; Mettenleiter, T.; Kager, A.

10.1101/2022.09.09.507285 — microbiology — Posted on 2022-09-09

3098 Human commensal Candida albicans strains demonstrate substantial within-host diversity and retained pathogenic potential

Anderson, F. M.; Visser, N.; Amses, K.; Hodgins-Davis, A.; Weber, A. M.; Metzner, K. M.; McFadden, M. J.; Mills, R. E.; O'Meara, M. J.; James, T. Y.; OMeara, T. R.

10.1101/2022.09.09.507247 — microbiology — Posted on 2022-09-09

3099 Comparative analysis of macroalgae supplementation on the rumen microbial community: Asparagopsis taxiformis inhibits major ruminal methanogenic, fibrolytic, and volatile fatty acid-producing microbes in vitro

O'Hara, E.; Moote, P. E.; Terry, S.; Beauchemin, K.; McAllister, T.; Abbott, W.; Gruninger, R. J.

10.1101/2022.09.08.507231 — microbiology — Posted on 2022-09-09

3100 Quantifying the bioavailable energy in an ancient hydrothermal vent on Mars and a modern Earth-based analogue.

Rucker, H. R.; Ely, T. D.; LaRowe, D. E.; Giovannelli, D.; Price, R. E.

10.1101/2022.09.09.507253 — microbiology — Posted on 2022-09-09

3101 Protein secretion zones within the Gram-positive cell wall

Strach, M.; Koch, F.; Fiedler, S.; Liebeton, K.; Graumann, P. L.

10.1101/2022.09.09.507258 — microbiology — Posted on 2022-09-09

3102 Genome analysis of Parmales, a sister group of diatoms, reveals the evolutionary specialization of diatoms from phago-mixotrophs to photoautotrophs

Ban, H.; Sato, S.; Yoshikawa, S.; Yamada, K.; Nakamura, Y.; Ichinomiya, M.; Sato, N.; Blanc-Mathieu, R.; Endo, H.; Kuwata, A.; Ogata, H.

10.1101/2022.09.09.507052 — microbiology — Posted on 2022-09-09

3103 Use of the particle agglutination/particle agglutination-inhibition test for antigenic analysis of SARS-CoV-2

Kobayashi, J.; Matsuyama, S.; Shirakura, M.; Arita, T.; Suzuki, Y.; Asanuma, H.; Watanabe, S.; Hasegawa, H.; Nakamura, K.

10.1101/2022.09.08.507221 — microbiology — Posted on 2022-09-09

3104 Mucosal vaccination for SARS-CoV-2 elicits superior systemic T central memory function and cross-neutralizing antibodies against variants of concern

ONeill, A.; Kala, M. P.; Tan, C. W.; Saron, W. A. A.; Mantri, C. K.; Rathore, A. P. S.; Wang, L.-F.; St. John, A. L.

10.1101/2022.09.09.507250 — immunology — Posted on 2022-09-09

3105 Seasonality of pollinators in Mediterranean montane habitats: cool-blooded bees for early-blooming plants

Herrera, C. M.; Nunez, A.; Aguado, L. O.; Alonso, C.

10.1101/2022.09.07.506992 — ecology — Posted on 2022-09-09

3106 (Pro)Renin Receptor Antagonism Attenuates High-Fat-Die-Induced Hepatic Steatosis in Non-Alcoholic Fatty Liver Disease

Gayban, A. J. B.; Souza, L.; Cooper, S. G.; Regalado, E.; Kleemann, R.; Feng Earley, Y.

10.1101/2022.09.07.506819 — pathology — Posted on 2022-09-09

3107 Probing Local Force Propagation in Tensed Fibrous Gels

Goren, S.; Levin, M.; Brand, G.; Lesman, A.; Sorkin, R.

10.1101/2022.09.07.506942 — biophysics — Posted on 2022-09-09

3108 SCING: Single Cell INtegrative Gene regulatory network inference elucidates robust, interpretable gene regulatory networks

Littman, R.; Wang, N.; Peng, C.; Yang, X.

10.1101/2022.09.07.506959 — bioinformatics — Posted on 2022-09-09

3109 Engineering High-Quality Cartilage Microtissues using Hydrocortisone Functionalised Microwells

Burdis, R.; Kronemberger, G. S.; Kelly, D. J.

10.1101/2022.09.07.507002 — bioengineering — Posted on 2022-09-09

3110 Natural variation in codon bias and mRNA folding strength interact synergistically to modify protein expression in Saccharomyces cerevisiae

Pollard, D. A.; Wienecke, A. N.; Barry, M. L.

10.1101/2022.09.07.507001 — genetics — Posted on 2022-09-09

3111 Aspects of flow variability and spatial context predict temporal beta diversity in river metacommunities

Saffarinia, P.; Conway, R.; Anderson, K. E.

10.1101/2022.09.07.506991 — ecology — Posted on 2022-09-09

3112 Aerosolized Desert Dusts Collected Near a Drying Lake and Pulmonary Inflammation in Mice: Implications for Environmental Exposures and Asthma

Biddle, T. A.; Yisrael, K.; Drover, R.; Li, Q.; Maltz, M. R.; Topacio, T. M.; Yu, J.; Del Castillo, D.; Gonzalez, D.; Freund, H. M.; Swenson, M. P.; Shapiro, M. L.; Botthoff, J. K.; Aronson, E. L.; Cocker, D. R.; Lo, D. D.

10.1101/2022.09.07.506987 — pharmacology and toxicology — Posted on 2022-09-09

3113 Competition between phage-resistance mechanisms determines the outcome of bacterial co-existence

Rendueles, O.; de Sousa, J. A.; Rocha, E. P. C.

10.1101/2022.07.11.499539 — evolutionary biology — Posted on 2022-09-09

3114 TORC1 phosphorylates and inhibits the ribosome preservation factor Stm1 to activate dormant ribosomes

Shetty, S.; Hofstetter, J.; Battaglioni, S.; Ritz, D.; Hall, M. N.

10.1101/2022.08.08.503151 — molecular biology — Posted on 2022-09-09

3115 Accumulation of copy-back viral genomes during respiratory syncytial virus infection is preceded by diversification of the copy-back viral genome population followed by selection

Felt, S. A.; Achouri, E.; Faber, S. R.; Lopez, C. B.

10.1101/2022.05.25.493350 — microbiology — Posted on 2022-09-09

3116 Genetic and physiological insights into the diazotrophic activity of a non-cyanobacterial marine diazotroph

Joublin-Delavat, A.; Touahri, K.; Cretin, P.; Morot, A.; Rodrigues, S.; Jesus, B.; Trigodet, F.; Delavat, F.

10.1101/2022.07.13.499682 — microbiology — Posted on 2022-09-09

3117 Amount of Pannexin 1 in smooth muscle cells regulates sympathetic nerve induced vasoconstriction

Dunaway, L. S.; Billaud, M.; Macal, E.; Good, M. E.; Medina, C.; Lorenz, U.; Ravichandran, K.; Koval, M.; Isakson, B. E.

10.1101/2022.09.07.506995 — physiology — Posted on 2022-09-09

3118 N-terminal cardiac myosin-binding protein C interactions with myosin and actin filaments using time-resolved FRET

Wong, F. L.; Bunch, T. A.; Lepak, V. C.; Colson, B. A.

10.1101/2022.09.07.507024 — biophysics — Posted on 2022-09-09

3119 Temporal enzymatic treatment to enhance the remodelling of multiple cartilage microtissues into a structurally organised tissue

Burdis, R.; Gallostra, X. B.; Kelly, D. J.

10.1101/2022.09.07.506986 — bioengineering — Posted on 2022-09-09

3120 Drosophila Atlastin regulates synaptic vesicle mobilization independent of Bone Morphogenetic Protein signaling

Bertin, F.; Jara-Wilde, J.; Auer, B.; Köhler-Solis, A.; Gonzalez-Silva, C.; Thomas, U.; Sierralta, J.

10.1101/2022.09.09.507308 — cell biology — Posted on 2022-09-09

3121 Apelin Stimulation of the Perivascular MuSC Niche Enhances Endogenous Repair in Muscular Dystrophy

Le Moal, E.; Liu, Y.; Collerette-Tremblay, J.; Dumontier, S.; Boutin, J.; Dort, J.; Orfi, Z.; Michaud, J.; Giguere, H.; Desroches, A.; Vezina, F.; Bedard, S.; Balg, F.; Sarret, P.; Scott, M. S.; Feige, J. N.; Denault, J.-B.; Dumont, N. A.; Marsault, E.; Auger-Messier, M.; Bentzinger, C. F.

10.1101/2022.09.09.507274 — cell biology — Posted on 2022-09-09

3122 Loss of ANT1 Increases Fibrosis and Epithelial Cell Senescence in Idiopathic Pulmonary Fibrosis

Boatz, J. C.; Sui, J.; Hu, Q.; Li, X.; Zhang, Y.; Koenigshoff, M.; Kliment, C.

10.1101/2022.09.09.507271 — cell biology — Posted on 2022-09-09

3123 Rapid emergence of extensively drug-resistant Shigella sonnei in France

Lefevre, S.; Njamkepo, E.; Feldman, S.; Ruckly, C.; Carle, I.; Lejay-Collin, M.; Fabre, L.; Yassine, I.; Frezal, L.; Pardos de la Gandara, M.; Fontanet, A.; Weill, F.-X.

10.1101/2022.09.07.506808 — microbiology — Posted on 2022-09-09

3124 Whole-body sorcin invalidation does not cause hypothalamic ER stress nor worsens obesity in C57BL/6 male mice fed a westernized diet.

Parks, S. Z.; Rutter, G. A.; Leclerc, I.

10.1101/2022.09.07.506981 — neuroscience — Posted on 2022-09-09

3125 Single-cell transcriptomics of resected human traumatic brain injury tissues reveals acute activation of endogenous retroviruses in oligodendrocytes

Garza, R.; Sharma, Y.; Atacho, D.; Hamdeh, S. A.; Jonsson, M. E.; Ingelsson, M.; Jern, P.; Hammell, M. G.; Englund, E.; Jakobsson, J.; Marklund, N.

10.1101/2022.09.07.506982 — neuroscience — Posted on 2022-09-09

3126 The thermoception task: a thermal-imaging based procedure for measuring awareness of changes in peripheral body temperature

Vabba, A.; Panasiti, M. S.; Scattolin, M.; Spitaleri, M.; Porciello, G.; Aglioti, S. M.

10.1101/2022.09.07.506983 — neuroscience — Posted on 2022-09-09

3127 Genetically Engineered Human Pituitary Corticotroph Tumor Organoids Exhibit Divergent Responses To Glucocorticoid Receptor Modulators

Mallick, S.; Chakrabarti, J.; Eschbacher, J.; Moraitis, A. G.; Greenstein, A. E.; Churko, J.; Pond, K. W.; Livolsi, A.; Thorne, C. A.; Little, A. S.; Yuen, K. C.; Zavros, Y.

10.1101/2022.09.07.506977 — physiology — Posted on 2022-09-09

3128 Mitotic tethering enables en masse inheritance of a shattered micronuclear chromosome

Cleveland, D. W.; Trivedi, P.; Steele, C. D.; Alexandrov, L. B.

10.1101/2022.09.08.507171 — cancer biology — Posted on 2022-09-09

3129 Accelerated ensemble generation for cyclic peptides using a Reservoir-REMD implementation in GROMACS

Hsueh, S. C. C.; Aina, A.; Plotkin, S. S.

10.1101/2022.09.07.507010 — biophysics — Posted on 2022-09-09

3130 CTCF is a DNA-tension-dependent barrier to cohesin-mediated DNA loop extrusion

Davidson, I. F.; Barth, R.; Zaczek, M.; van der Torre, J.; Tang, W.; Nagasaka, K.; Janissen, R.; Kerssemakers, J.; Wutz, G.; Dekker, C.; Peters, J.-M.

10.1101/2022.09.08.507093 — biophysics — Posted on 2022-09-09

3131 A dynamic template complex mediates Munc18-chaperoned SNARE assembly

Yang, J.; Jin, H.; Liu, Y.; Guo, Y.; Zhang, Y.

10.1101/2022.09.09.507208 — biophysics — Posted on 2022-09-09

3132 Synergising single-cell resolution and 4sU labelling boosts inference of transcriptional bursting

Edwards, D. M.; Davies, P.; Hebenstreit, D.

10.1101/2022.09.08.506961 — bioinformatics — Posted on 2022-09-09

3133 p57Kip2 acts as a transcriptional corepressor to regulate intestinal stem cell fate and proliferation

Creff, J.; Nowosad, A.; Prel, A.; Pizzocaro, A.; Aguirrebengoa, M.; Duquesnes, N.; Callot, C.; Jungas, T.; Dozier, C.; Besson, A.

10.1101/2022.09.09.507138 — cell biology — Posted on 2022-09-09

3134 Open spaced ridged hydrogel scaffolds containing TiSAMP surface chemistry promotes regeneration and recovery following spinal cord injury.

Siddiqui, A. M.; Thiele, F.; Stewart, R. N.; Rangnick, S.; Weiss, G. J.; Chen, B. K.; Silvernail, J. L.; Strickland, T.; Nesbitt, J. J.; Lim, K.; Schwarzbauer, J. E.; Schwartz, J.; Yaszemski, M. J.; Windebank, A. J.; Madigan, N. N.

10.1101/2022.09.07.506969 — neuroscience — Posted on 2022-09-09

3135 Neurostimulation Artifact Removal for Implantable Sensors Improves Signal Clarity and Decoding of Motor Volition

Earley, E. J.; Berneving, A.; Zbinden, J.; Ortiz-Catalan, M.

10.1101/2022.09.07.506955 — neuroscience — Posted on 2022-09-09

3136 A cocktail of rapamycin, acarbose and phenylbutyrate prevents age-related cognitive decline in mice by altering aging pathways

Ladiges, W. C.; Jiang, Z.; He, Q.

10.1101/2022.09.07.506968 — systems biology — Posted on 2022-09-09

3137 DELLA proteins regulate spore germination and reproductive development in Physcomitrium patens.

Phokas, A.; Meyberg, R.; Briones-Moreno, A.; Hernandez-Garcia, J.; Wadsworth, P. T.; Vesty, E. F.; Blazquez, M. A.; Rensing, S. A.; Coates, J. C.

10.1101/2022.09.07.506957 — plant biology — Posted on 2022-09-09

3138 Distinct selection signatures during domestication and improvement in crops: a tale of two genes in mungbean

Lin, Y.-P.; Chen, H.-W.; Yeh, P.-M.; Lin, J.; Anand, S.; Li, J.; Noble, T.; Nair, R. M.; Schafleitner, R.; Samsonova, M.; Bishop-von-Wettberg, E.; Nuzhdin, S.; Ting, C.-T.; Lawn, R.; Lee, C.-R.

10.1101/2022.09.08.506689 — plant biology — Posted on 2022-09-09

3139 Extracellular Carbonic Anhydrase Supports Constitutive HCO3- Uptake in Fragilariopsis cylindrus Regardless of Temperature Changes

Li, M.; Young, J. N.

10.1101/2022.09.08.507187 — plant biology — Posted on 2022-09-09

3140 Various tomato cultivars display contrasted morphological and molecular responses to a heat wave.

Bollier, N.; Micol-Ponce, R.; Dakdaki, A.; Maza, E.; Zouine, M.; Djari, A.; Bouzayen, M.; Chevalier, C.; Delmas, F.; Gonzalez, N.; Hernould, M.

10.1101/2022.09.08.507118 — plant biology — Posted on 2022-09-09

3141 The Sw-5b NLR immune receptor induces earlier transcriptional changes in response to thrips-mediated inoculation of Tomato spotted wilt orthotospovirus compared to mechanical inoculation

Ordaz, N. A.; Nagalakshmi, U.; Boiteux, L. S.; Atamian, H. S.; Ullman, D. E.; Dinesh-Kumar, S. P.

10.1101/2022.09.07.507022 — plant biology — Posted on 2022-09-09

3142 A Plastidial Glycolytic-Gluconeogenic Switch of Mitochondrial Origin Enables Diatom Adaptations to High Latitudes

Dorrell, R. G.; Liang, Y.; Gueguen, N.; Nonoyama, T.; Zhang, Y.; Croteau, D.; Penot, M.; Adiba, S.; Bailleul, B.; Gros, V.; Karlusich, J. J. P.; Zweig, N.; Fernie, A. R.; Jouhet, J.; Marechal, E.; Bowler, C.

10.1101/2022.09.08.507166 — plant biology — Posted on 2022-09-09

3143 Dissection of genotype-by-environment interaction and simultaneous selection for grain yield and stability in faba bean (Vicia faba L.)

Gela, T. S.; Khazaei, H.; Podder, R.; Vandenberg, A.

10.1101/2022.09.08.507215 — plant biology — Posted on 2022-09-09

3144 An Optimized Approach to Study Sub-Sarcomere Structure Utilizing Super-Resolution Microscopy with Secondary VHH Nanobodies

Douglas, C. M.; Bird, J. E.; Kopinke, D.; Esser, K. A.

10.1101/2022.09.07.506832 — physiology — Posted on 2022-09-09

3145 Low Molecular Weight Hyaluronan Inhibits Lung Epithelial Ion Channels by Activating Calcium-Sensing Receptor

Lazrak, A.; Song, W.; Yu, Z.; Zhang, S.; Nellore, A.; Hoopes, C. W.; Woodworth, B. A.; Matalon, S.

10.1101/2022.09.07.506946 — physiology — Posted on 2022-09-09

3146 Preclinical shortwave infrared tumor screening and resection via pHLIP ICG under ambient lighting conditions

Mc Larney, B. E.; Kim, M.; Roberts, S.; Skubal, M.; Hsu, H.-T.; Ogirala, A.; PILLARSETTY, N.; Heller, D. A.; Lewis, J. S.; Grimm, J.

10.1101/2022.09.07.506973 — cancer biology — Posted on 2022-09-09

3147 Biologically relevant integration of transcriptomics profiles from cancer cell lines, patient-derived xenografts and clinical tumors using deep neural networks

Dimitrieva, S.; Janssens, R.; Li, G.; Szalata, A.; Gopal, R.; Parmar, C.; Kauffmann, A.; Durand, E. Y.

10.1101/2022.09.07.506964 — bioinformatics — Posted on 2022-09-09

3148 Strategies and Techniques for Quality Control and Semantic Enrichment with Multimodal Data: A Case Study in Colorectal Cancer with eHDPrep

Toner, T.; Miller, P.; Forster, T.; Coleman, H.; Overton, I. M.

10.1101/2022.09.07.506953 — bioinformatics — Posted on 2022-09-09

3149 Are brain displacements and pressures within the parenchyma induced by surface pressure differences? A computational modelling study

Piersanti, E.; Rognes, M. E.; Vinje, V.

10.1101/2022.09.07.506967 — bioengineering — Posted on 2022-09-09

3150 Exploring high-quality microbial genomes by assembly of linked-reads with high barcode specificity using deep learning

Zhang, Z.; Wang, H.; Yang, C.; Yufen, H.; Yue, Z.; Chen, Y.; Han, L.; Lu, A.; Fang, X.; Zhang, L.

10.1101/2022.09.07.506963 — genomics — Posted on 2022-09-09

3151 Shifts in isoform usage underlie transcriptional differences in regulatory T cells in type 1 diabetes

Newman, J. R. B.; Long, S. A.; Speake, C.; Greenbaum, C. J.; Cerosaletti, K.; Rich, S. S.; Onengut-Gumuscu, S.; McIntyre, L.; Concannon, P.

10.1101/2022.09.07.506965 — genetics — Posted on 2022-09-09

3152 Grasshopper genome reveals long-term conservation of the X chromosome and temporal variation in X chromosome evolution

Li, X.; Mank, J.; Ban, L.

10.1101/2022.09.08.507201 — evolutionary biology — Posted on 2022-09-09

3153 Testing Wright's Intermediate Population Size Hypothesis - When Genetic Drift is a Good Thing

Cruzan, M.

10.1101/2022.09.07.506960 — evolutionary biology — Posted on 2022-09-09

3154 Turbulent adaptive landscape shaped size evolution in modern ocean giants

Burin, G.; Park, T.; James, T. D.; Slater, G.; Cooper, N.

10.1101/2022.09.07.506945 — evolutionary biology — Posted on 2022-09-09

3155 Maternal provisioning of an obligate symbiont

Carrier, T. J.; Schmittmann, L.; Jung, S.; Pita, L.; Hentschel, U.

10.1101/2022.09.07.506999 — evolutionary biology — Posted on 2022-09-09

3156 Evolutionary rates in human amyloid proteins reveal their intrinsic metastability

Zea, D.; Mac Donagh, J.; Benitez, G.; Donadio, C. E. G.; Marchetti, J.; Palopoli, N.; Fornasari, M. S.; Parisi, G.

10.1101/2022.09.07.506994 — evolutionary biology — Posted on 2022-09-09

3157 Heterologous boost with mRNA vaccines against SARS-CoV-2 Delta/Omicron variants following an inactivated whole-virus vaccine

10.1101/2022.09.06.506714 — molecular biology — Posted on 2022-09-09

3158 The topological shape of gene expression across the evolution of flowering plants

Palande, S.; Kaste, J. A. M.; Roberts, M. D.; Segura Aba, K.; Claucherty, C.; Dacon, J.; Doko, R.; Jayakody, T. B.; Jeffery, H. R.; Kelly, N.; Manousidaki, A.; Parks, H. M.; Roggenkamp, E. M.; Schumacher, A. M.; Yang, J.; Percival, S.; Pardo, J.; Husbands, A. Y.; Krishnan, A.; Montgomery, B. L.; Munch, E.; Thompson, A. M.; Rougon-Cardoso, A.; Chitwood, D. H.; VanBuren, R.

10.1101/2022.09.07.506951 — plant biology — Posted on 2022-09-09

3159 lincRNA RP24-315D19.10 promotes endometrialdecidualization via upregulation of hnRNPA2B1

Tan, L.; Gao, R.; Chen, X.; Geng, Y.; Yin, X.; Chuan, P.; Mu, X.; Su, Y.; Zhang, Y.; Li, F.; He, J.

10.1101/2022.09.07.506883 — molecular biology — Posted on 2022-09-09

3160 Leaf-level metabolic changes in response to drought affect daytime CO2 emission and isoprenoid synthesis

Ladd, S. N.; Daber, L. E.; Bamberger, I.; Kuebert, A.; Kreuzwieser, J.; Purser, G.; Ingrisch, J.; Deleeuw, J.; van Haren, J.; Meredith, L.; Werner, C.

10.1101/2022.04.29.490001 — plant biology — Posted on 2022-09-09

3161 High-throughput field phenotyping reveals that selection in breeding has affected the phenology and temperature response of wheat in the stem elongation phase

Roth, L.; Kronenberg, L.; Aasen, H.; Walter, A.; Hartung, J.; van Eeuwijk, F. A.; Piepho, H.-P.; Hund, A.

10.1101/2022.09.05.506627 — physiology — Posted on 2022-09-09

3162 Contact Stiffness Governs Mechanoresponses of Living Cells to Extracellular Microenvironment

Zhao, P.; Zheng, Y.; Zhang, Z.-Y.; Jiang, M.-W.; Jiang, Y.-X.; Du, J.; Cao, Y.-P.

10.1101/2022.09.07.506641 — biophysics — Posted on 2022-09-09

3163 Single-cell analysis of bovine muscle-derived cell types for cultured meat production

Messmer, T.; Dohmen, R. G.; Schaeken, L.; Melzener, L.; Hueber, R.; Godec, M.; Post, M. J.; Flack, J. E.

10.1101/2022.09.02.506369 — cell biology — Posted on 2022-09-09

3164 (-)-Gossypol inhibition of musashi-mediated forgetting improves memory and age-dependent memory decline in Caenorhabditis elegans

Mastrandreas, P.; Arnold, A.; Boglari, C.; de Quervain, D.; Stetak, A.; Papassotiropoulos, A.

10.1101/2022.06.20.496809 — neuroscience — Posted on 2022-09-09

3165 CONNECTOR, fitting and clustering of longitudinal data to reveal a new risk stratification system.

Pernice, S.; Sirovich, R.; Grassi, E.; Viviani, M.; Ferri, M.; Sassi, F.; Alessandri, L.; Tortarolo, D.; Calogero, R. A.; Trusolino, L.; Bertotti, A.; Beccuti, M.; Olivero, M.; Cordero, F.

10.1101/2022.08.08.503120 — bioinformatics — Posted on 2022-09-09

3166 MOAHIT: a web tool for visualizing tumor multi-omics data with human anatomy heatmaps

Zhou, C.; Lin, A.; Zhang, J.; Luo, P.

10.1101/2022.09.07.506938 — bioinformatics — Posted on 2022-09-09

3167 Evolution of predictive memory in the hippocampus

Miller, A. M. P.; Jacob, A. D.; Ramsaran, A. I.; De Snoo, M. L.; Josselyn, S. A.; Frankland, P. W.

10.1101/2022.09.08.507204 — neuroscience — Posted on 2022-09-09

3168 Semantic-Specific and Domain-General Mechanisms for Integration and Update of Contextual Information

Branzi, F.; Lambon-Ralph, M.

10.1101/2022.09.08.507135 — neuroscience — Posted on 2022-09-09

3169 Dysregulation of The Chromatin Environment Leads to Differential Alternative Splicing as A Mechanism Of Disease In a Human Model of Autism Spectrum Disorders

Leung, C. S.; Rosenzweig, S.; Yoon, B.; Marinelli, N. A.; Hollingsworth, E. W.; Maguire, A. M.; Cowen, M. M.; Schmidt, M.; Imitola, J.; Uzun, E. D. G.; Lizarraga, S. B.

10.1101/2022.09.08.507162 — neuroscience — Posted on 2022-09-09

3170 Attentional enhancement of tracked stimuli in early visual cortex has strict capacity limits

Adamian, N.; Andersen, S. K.

10.1101/2022.09.08.507113 — animal behavior and cognition — Posted on 2022-09-09

3171 The functional impact of rare variation across the regulatory cascade

Li, T.; Ferraro, N.; Strober, B. J.; Aguet, F.; Kasela, S.; Arvanitis, M.; Ni, B.; van de Wiel, L.; Hershberg, E.; Ardlie, K.; Arking, D. E.; Beer, R. L.; Brody, J.; Blackwell, T. W.; Clish, C.; Gabriel, S.; Gerszten, R.; Guo, X.; Gupta, N.; Johnson, W. C.; Lappalainen, T.; Lin, H. J.; Liu, Y.; Nickerson, D. A.; Papanicolaou, G.; Pritchard, J. K.; Qasba, P.; Shojaie, A.; Smith, J.; Sotoodehnia, N.; Taylor, K. D.; Tracy, R. P.; Van den Berg, D.; Wheeler, M.; Rich, S. S.; Rotter, J. I.; Battle, A. J.; Montgomery, S. B.

10.1101/2022.09.07.507008 — genomics — Posted on 2022-09-09

3172 The Neuroscience Multi-Omic Archive: A BRAIN Initiative resource for single-cell transcriptomic and epigenomic data from the mammalian brain

Ament, S. A.; Adkins, R. S.; Carter, R.; Chrysostomou, E.; Colantuoni, C.; Crabtree, J.; Creasy, H. H.; Degatano, K.; Kiernan, E.; Felix, V.; Gandt, P.; Garden, G. A.; Giglio, M.; Herb, B. R.; Khajouei, F.; Nickel, L.; McCracken, C.; McDaniel, K.; Nadendla, S.; Olley, D.; Orvis, J.; Receveur, J.; Schor, M.; Tickle, T. L.; Way, J.; Hertzano, R.; Mahurkar, A. A.; White, O. R.

10.1101/2022.09.08.505285 — genomics — Posted on 2022-09-09

3173 Distinguishing between histories of speciation and introgression using genomic data

Hibbins, M. S.; Hahn, M. W.

10.1101/2022.09.07.506990 — evolutionary biology — Posted on 2022-09-09

3174 The Nanog epigenetic remodeling complex was essential to vertebrate mesoderm evolution

Simpson, L.; Crowley, D.; Forey, T.; Acosta, H.; Ferjentsik, Z.; Chatfield, J.; Payne, A.; Simpson, B.; Redwood, C.; Dixon, J.; Holmes, N.; Sang, F.; Alberio, R.; Loose, M.; Johnson, A. D.

10.1101/2022.09.08.507069 — developmental biology — Posted on 2022-09-09

3175 Migrating mesoderm cells self-organize into a dynamic meshwork structure during chick gastrulation

Nakaya, Y.; Tarama, M.; Tasaki, S.; Isomura, A.; Shibata, T.

10.1101/2022.09.08.507227 — developmental biology — Posted on 2022-09-09

3176 Identification of the Metaphyseal Skeletal Stem Cell

Yang, G.; He, Q.; Guo, X.; Li, R.-Y.; Lin, J.; Tao, W.; Liu, W.; Lin, H.; Tang, M.; Xing, S.; Qi, Y.; Peng, Y.; Dong, L.; Han, J.-D. J.; Zhou, B.; Teng, Y.; Yang, X.

10.1101/2022.09.08.506930 — developmental biology — Posted on 2022-09-09

3177 RTK signalling promotes epithelial columnar cell shape and apical junction maintenance in human lung progenitor cells

Liu, S.; Sun, D.; Butler, R.; Rawlins, E. L.

10.1101/2022.09.08.507126 — developmental biology — Posted on 2022-09-09

3178 Ectodysplasin signaling via Xedar is required for mammary gland morphogenesis

Wark, A. R.; Tomizawa, R.; Aldea, D.; Kokalari, B.; Warder, B.; Kamberov, Y. G.

10.1101/2022.09.08.507158 — developmental biology — Posted on 2022-09-09

3179 Mediator 1 ablation induces enamel-to-hair lineage conversion through enhancer dynamics

Thaler, R.; Yoshizaki, K.; Nguyen, T.; Fukumoto, S.; DenBesten, p.; Bikle, D. D.; Oda, Y.

10.1101/2022.09.08.507153 — developmental biology — Posted on 2022-09-09

3180 FRIZZLED 2 regulates limb development by mediating both β-catenin-dependent and independent Wnt signaling pathways

Zhu, X.; Xu, M.; Leu, N. A.; Morrisey, E. E.; Millar, S. E.

10.1101/2022.09.08.507207 — developmental biology — Posted on 2022-09-09

3181 Identification of a chemical probe for lipid kinase phosphatidylinositol-5-phosphate 4-kinase gamma (PI5P4Kγ)

Drewry, D. H.; Potjewyd, F. M.; Smith, J. L.; Howell, S.; Axtman, A. D.

10.1101/2022.09.08.507203 — cell biology — Posted on 2022-09-09

3182 Systematic analysis of microtubule plus-end networks defines EB-cargo complexes critical for mitosis in budding yeast

Kornakov, N.; Westermann, S.

10.1101/2022.09.08.507099 — cell biology — Posted on 2022-09-09

3183 When Abstract Becomes Concrete: Naturalistic Encoding of Concepts in the Brain

Kewenig, V. N.; Vigliocco, G.; Skipper, J. I.

10.1101/2022.09.08.506944 — neuroscience — Posted on 2022-09-09

3184 Adaptive Encoding Speed in Working Memory

de Jong, J.; van Rijn, H.; Akyurek, E.

10.1101/2022.09.08.507070 — neuroscience — Posted on 2022-09-09

3185 Re-genotyping structural variants through an accurate force-calling method

Cao, S.; Jiang, T.; Liu, Y.; Liu, S.; Wang, Y.

10.1101/2022.08.29.505534 — bioinformatics — Posted on 2022-09-09

3186 Structure and Function of Gli123 Involved in Mycoplasma mobile Gliding

Matsuike, D.; Tahara, Y. O.; Nonaka, T.; Hamaguchi, T.; Kudo, H.; Hayashi, Y.; Arai, M.; Miyata, M.

10.1101/2022.09.07.507039 — microbiology — Posted on 2022-09-09

3187 Quantifying variability in population abundances

Schlemmer, M.

10.1101/2022.02.19.481101 — ecology — Posted on 2022-09-08

3188 Expression Ratios of the Anti-Apoptotic BCL2 Family Members Dictate the Selective Addiction of KSHV-Transformed Primary Effusion Lymphoma Cell Lines to MCL1

Dunham, D.; Viswanathan, P.; Gill, J.; Manzano, M.

10.1101/2022.09.07.507059 — microbiology — Posted on 2022-09-08

3189 Tissue confinement regulates cell growth and size in epithelia

Devany, J.; Falk, M. J.; Holt, L. J.; Murugan, A.; Gardel, M.

10.1101/2022.07.04.498508 — biophysics — Posted on 2022-09-08

3190 RTX-KG2: a system for building a semantically standardized knowledge graph for translational biomedicine

Wood, E. C.; Glen, A. K.; Kvarfordt, L. G.; Womack, F.; Acevedo, L.; Yoon, T. S.; Ma, C.; Flores, V.; Sinha, M.; Chodpathumwan, Y.; Termehchy, A.; Roach, J. C.; Mendoza, L.; Hoffman, A. S.; Deutsch, E. W.; Koslicki, D.; Ramsey, S. A.

10.1101/2021.10.17.464747 — bioinformatics — Posted on 2022-09-08

3191 Extraction and characterization of cellulose from invasive weeds from central Nepal: A potential prospect of environmental management.

Dhakal, S.; Tiwari, A.; Adhikari, A.; Shrestha, S. K.; Adhikari, B.

10.1101/2022.09.08.507090 — biochemistry — Posted on 2022-09-08

3192 More than 90% of nacre matrix proteins are composed of silk-like proteins

Liu, X.; Yin, Z.; Ma, Z.; Liang, J.; Yao, L.; Zhang, R.

10.1101/2022.09.07.507049 — biochemistry — Posted on 2022-09-08

3193 A genome-wide CRISPR functional survey of the human phagocytosis molecular machinery

Essletzbichler, P.; Sedlyarov, V.; Frommelt, F.; Soulat, D.; Heinz, L. X.; Stefanovic, A.; Neumayer, B.; Superti-Furga, G.

10.1101/2022.09.08.507072 — genomics — Posted on 2022-09-08

3194 Expression of m6A RNA methylation markers in the hypothalamus of Atlantic salmon

Ahi, E. P.; Frapin, M.; Hukkanen, M.; Primmer, C. R.

10.1101/2022.09.08.507106 — molecular biology — Posted on 2022-09-08

3195 Increasing number of long-lived ancestors associates with up to a decade of healthspan extension and a healthy metabolomic profile in mid-life

Berg, N. v. d.; Rodriguez-Girondo, M.; van Dijk, I. K.; Slagboom, P. E.; Beekman, M.

10.1101/2022.09.08.507098 — molecular biology — Posted on 2022-09-08

3196 A novel fluorobenzothiazole RBx 10080758 as a dual inhibitor against bacterial GyraseB (GyrB) and Topoisomerase IV (parE) of Gram-positive pathogens causing skin and respiratory infections

10.1101/2022.09.08.507076 — microbiology — Posted on 2022-09-08

3197 Genomic and ecologic characteristics of the airway microbial-mucosal complex

Cuthbertson, L.; Lober, U.; Ish-Horowicz, J. S.; McBrien, C. N.; Churchward, C.; Parker, J. C.; Olanipekun, M. T.; Burke, C.; O'Carroll, O.; Faul, J.; Davies, G. A.; Lewis, K. E.; Hopkin, J. M.; Creaser-Thomas, J.; Ghosal, R.; Chung, K. F.; Willis-Owen, S. A. G.; Piatek, S.; Bartolomaeus, T.; Birkner, T.; Dwyer, S.; Kumar, N.; Turek, E. M.; Musk, W. A.; Hui, J.; Hunter, M.; James, A.; Dumas, M.-E.; Fillipi, S.; Cox, M. J.; Lawley, T. D.; Forslund, S. K.; Moffatt, M. F.; Cookson, W. O. C.

10.1101/2022.09.08.507073 — microbiology — Posted on 2022-09-08

3198 A link between genotype and cellular architecture in microbiome members as revealed by cryo-EM

Wimmer, B. H.; Morais, S.; Zalk, R.; Mizrahi, I.; Medalia, O.

10.1101/2022.09.08.507075 — microbiology — Posted on 2022-09-08

3199 Dual-Fluorescent Reporter for Live-Cell Imaging of the ER During DENV Infection

Corliss, L.; Holliday, M.; Lennemann, N. J.

10.1101/2022.09.08.507164 — microbiology — Posted on 2022-09-08

3200 Polycomb repressive complex 1.1 coordinates homeostatic and emergency myelopoiesis

Nakajima-Takagi, Y.; Oshima, M.; Takano, J.; Koide, S.; Itokawa, N.; Uemura, S.; Yamashita, M.; Andoh, S.; Aoyama, K.; Isshiki, Y.; Shinoda, D.; Saraya, A.; Arai, F.; Yamaguchi, K.; Furukawa, Y.; Koseki, H.; Ikawa, T.; Iwama, A.

10.1101/2022.09.07.507016 — immunology — Posted on 2022-09-08

3201 Single-Molecule Analysis of DNA Base-Stacking Energetics Using Patterned DNA Nanostructures

Banerjee, A.; Anand, M.; Kalita, S.; Ganji, M.

10.1101/2022.09.08.506950 — biophysics — Posted on 2022-09-08

3202 Enhanced intrathecal drug dispersion achieved by high volume injection and natural micromixing

Ayansiji, A. O.; Gehrke, D. S.; Baralle, B.; Nozain, A.; Meenesh, S. R.; Linninger, A. A.

10.1101/2022.03.22.485353 — bioengineering — Posted on 2022-09-08

3203 Truncated RNA-binding protein production by DUX4-induced systemic inhibition of nonsense-mediated RNA decay

Campbell, A. E.; Dyle, M. C.; Calviello, L.; Matheny, T.; Sudheendran, K.; Cortazar, M. A.; Forman, T.; Fu, R.; Gillen, A. E.; Caruthers, M. H.; Floor, S. N.; Jagannathan, S.

10.1101/2021.06.28.450189 — genomics — Posted on 2022-09-08

3204 Assessing the impact of fire on spiders through a global comparative analysis

McLean, C. A.; Melville, J.; Schubert, J.; Rose, R.; Medina, I.

10.1101/2021.12.20.472855 — ecology — Posted on 2022-09-08

3205 Diversity, composition, altitude, and seasonality of high-altitude windborne migrating mosquitoes in the Sahel: Implications for disease transmission

Yaro, A. S.; Linton, Y.-M.; Diallo, M.; Sanogo, Z. L.; Samake, D.; Ousman, Y.; Kouam, C.; Krajacich, B. J.; Faiman, R.; Bamou, R.; Woo, J.; Chapman, J.; Reynolds, D. R.; Lehmann, T.

10.1101/2022.08.19.504620 — ecology — Posted on 2022-09-08

3206 Cytomotive actins and tubulins share a polymerisation switch mechanism conferring robust dynamics

Wagstaff, J. M.; Planelles-Herrero, V. J.; Sharov, G.; Alnami, A.; Kozielski, F. G.; Derivery, E.; Löwe, J.

10.1101/2022.09.08.507146 — molecular biology — Posted on 2022-09-08

3207 Activity of EGFR transmembrane region variants indicates specific transmembrane dimers are not required for EGFR activity

Bartzoka, F.; Gonzalez-Magaldi, M.; Byrne, P. O.; Callery, N. I.; Hristova, K.; Leahy, D. J.

10.1101/2022.09.08.507182 — molecular biology — Posted on 2022-09-08

3208 Potentiation of Adipogenesis by Reactive Oxygen Species is a Unifying Mechanism in the Pro-adipogenic Properties of Bisphenol A and its New Structural Analogues.

Singh, R. D.; Wager, J. L.; Scheidl, T. B.; Connors, L. T.; Easson, S.; Callaghan, M. A.; Alatorre-hinojosa, S.; Swift, L. H.; Colarusso, P.; Jadli, A.; SHUTT, T.; Patel, V.; Thompson, J.

10.1101/2022.09.08.507176 — molecular biology — Posted on 2022-09-08

3209 A widespread family of phage-inducible chromosomal islands only steals bacteriophage tails to spread in nature

Alqurainy, N.; Miguel-Romero, L.; Moura de Sousa, J.; Chen, J.; Rocha, E. P. C.; Fillol-Salom, A.; Penades, J. R.

10.1101/2022.09.08.507074 — microbiology — Posted on 2022-09-08

3210 Camellia sinensis solvent extract confers trophocidal and cysticidal effects against Acanthamoeba castellanii

Fakae, L. B.; Harun, M. S. R.; Ting, D. S. J.; Dua, H. S.; Cave, G. W. V.; Zhu, X.-Q.; Stevenson, C. W.; Elsheikha, H. M.

10.1101/2022.09.08.507025 — microbiology — Posted on 2022-09-08

3211 Real-time visualization of phagosomal pH manipulation by Cryptococcus neoformans in an immune signal-dependent way

Santiago-Burgos, E. J.; Stuckey, P. V.; Santiago-Tirado, F. H.

10.1101/2022.09.08.507177 — microbiology — Posted on 2022-09-08

3212 PlrA (MSMEG_5223) is an essential polar growth regulator in Mycobacterium smegmatis

Quintanilla, S. Y.; Arejan, N. H.; Patel, P. B.; Boutte, C.

10.1101/2022.09.08.507195 — microbiology — Posted on 2022-09-08

3213 HPV E6 upregulates MARCHF8 ubiquitin ligase and inhibits apoptosis by degrading the death receptors in head and neck cancer

Khalil, M. I.; Yang, C.; Vu, L.; Chadha, S.; Welbon, C.; James, C. D.; Morgan, I. M.; Spanos, W. C.; Pyeon, D.

10.1101/2022.09.07.507063 — microbiology — Posted on 2022-09-08

3214 A clinical stage LMW-DS drug inhibits cell infection by coronaviruses and modulates reactive cytokine release from microglia

Logan, A.; Mazzon, M.; Bruce, L.; Barnes, N. M.

10.1101/2022.09.07.506919 — immunology — Posted on 2022-09-08

3215 Immunometabolic profiling of in vitro and ex vivo Leishmania-infected macrophages (LIMs) reveals unique polarization and bioenergetic signatures

Zhang, S.; Lecoeur, H.; Varet, H.; Legendre, R.; Mahtal, N.; Proux, C.; Aulner, N.; Short, S.; Grandjean, C.; Bousso, P.; Prina, E.; Spaeth, G. F.

10.1101/2022.09.08.507100 — immunology — Posted on 2022-09-08

3216 Disruption of lysosomal proteolysis in astrocytes facilitates midbrain proteostasis failure in an early-onset PD model.

Morrone Parfitt, G.; Coccia, E.; Goldman, C.; Whitney, K.; Reyes, R.; Sarrafha, L.; Nam, K. H.; Sohail, S.; Jones, D.; crary, J. F.; Ordureau, A.; Blanchard, J.; Ahfeldt, T. D.

10.1101/2022.08.26.505472 — neuroscience — Posted on 2022-09-08

3217 Conjunctive and complementary CA1 hippocampal cell populations relate sensory events to immobility and locomotion

Inayat, S.; McAllister, B. B.; Whishaw, I. Q.; Mohajerani, M. H.

10.1101/2022.07.06.498996 — neuroscience — Posted on 2022-09-08

3218 Many but not all deep neural network audio models capture brain responses and exhibit hierarchical region correspondence

Tuckute, G.; Feather, J.; Boebinger, D.; McDermott, J. H.

10.1101/2022.09.06.506680 — neuroscience — Posted on 2022-09-08

3219 Evolutionary Divergence in the Conformational Landscapes of Tyrosine vs Serine/Threonine Kinases

Gizzio, J.; Thakur, A.; Haldane, A.; Levy, R. M.

10.1101/2022.08.29.505757 — biophysics — Posted on 2022-09-08

3220 Rapid, DNA-induced subunit exchange by DNA gyrase

Germe, T.; Bush, N. G.; Baskerville, V.; Saman, D.; Benesch, J. L.; Maxwell, A.

10.1101/2022.09.08.507137 — biochemistry — Posted on 2022-09-08

3221 A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation

Bahar, M. W.; Nasta, V.; Fox, H.; Sherry, L.; Grehan, K.; Porta, C.; Macadam, A. J.; Stonehouse, N. J.; Rowlands, D. J.; Fry, E. E.; Stuart, D. I.

10.1101/2022.09.08.507136 — biochemistry — Posted on 2022-09-08

3222 Asgard ESCRT-IIIs assemble into helical filaments in the presence of DNA and remodel eukaryotic membranes

Melnikov, N.; Nachmias, D.; Halbi, G.; Upcher, A.; Zalk, R.; Bernheim, A.; Elia, N.

10.1101/2022.09.07.506706 — biochemistry — Posted on 2022-09-08

3223 Cryo-EM analyses of wild-type and oncogenic KIT mutants reveal structural oncogenic plasticity and a novel Achilles heel for therapeutic intervention

Krimmer, S. G.; Bertoletti, N.; Suzuki, Y.; Katic, L.; Mohanty, J.; Shu, S.; Lee, S.; Lax, I.; Mi, W.; Schlessinger, J.

10.1101/2022.09.08.506998 — biochemistry — Posted on 2022-09-08

3224 Overcoming Attenuation Bias in Regressions using Polygenic Indices: A Comparison of Approaches

van Kippersluis, H.; Biroli, P.; Galama, T. J.; von Hinke, S.; Meddens, S. F. W.; Muslimova, D.; Pereira, R.; Slob, E. A. W.; de Vlaming, R.; Rietveld, C. A.

10.1101/2021.04.09.439157 — genetics — Posted on 2022-09-08

3225 Missingness Adapted Group Informed Clustered (MAGIC)-LASSO: A novel paradigm for prediction in data with widespread non-random missingness

Gentry, A. E.; Kirkpatrick, R. M.; Peterson, R. E.; Webb, B. T.

10.1101/2021.04.29.442057 — genetics — Posted on 2022-09-08

3226 Spatial structure alters the site frequency spectrum produced by hitchhiking

Min, J.; Gupta, M.; Desai, M. M.; Weissman, D.

10.1101/2022.06.08.495311 — evolutionary biology — Posted on 2022-09-08

3227 Scleraxis-lineage cells are required for tendon homeostasis and their depletion induces an accelerated extracellular matrix aging phenotype

Korcari, A.; Nichols, A. E.; Loiselle, A. E.

10.1101/2022.01.20.477119 — cell biology — Posted on 2022-09-08

3228 Oncogenic YAP mediates changes in chromatin accessibility and activity that drive cell cycle gene expression and cell migration

Fetiva, M. C.; Liss, F.; Gertzmann, D.; Thomas, J.; Gantert, B.; Vogl, M.; Sira, N.; Weinstock, G.; Kneitz, S.; Ade, C. P.; Gaubatz, S.

10.1101/2022.09.08.507127 — molecular biology — Posted on 2022-09-08

3229 Development of Kaptive databases for Vibrio parahaemolyticus O- and K-antigen serotyping

van der Graaf - van Bloois, L.; Chen, H.; Wagenaar, J. A.; Zomer, A. L.

10.1101/2021.07.06.451262 — microbiology — Posted on 2022-09-08

3230 Robust control of replication initiation in the absence of DnaA-ATP {leftrightharpoons} DnaA-ADP regulatory elements in Escherichia coli

Boesen, T.; Charbon, G.; Fu, H.; Jensen, C.; Li, D.; Jun, S.; Lobner-Olesen, A.

10.1101/2022.09.08.507175 — microbiology — Posted on 2022-09-08

3231 Structure and Function of Gli123 Involved in Mycoplasma mobile Gliding

Matsuike, D.; Tahara, Y. O.; Nonaka, T.; Hamaguchi, T.; Kudo, H.; Hayashi, Y.; Arai, M.; Miyata, M.

10.1101/2022.09.07.507039 — microbiology — Posted on 2022-09-08

3232 Pre-existing immunity to influenza viruses through infection and/or vaccination leads to viral mutational signatures associated with unique immune responses during a subsequent infection

Rioux, M.; Ge, A.; Yourkowski, A.; Francis, M. E.; McNeil, M.; Selim, A.; Xue, B.; Darbellay, J.; Kelvin, A. A.

10.1101/2022.09.07.507060 — microbiology — Posted on 2022-09-08

3233 Small RNAs activate Salmonella pathogenicity island 1 by modulating mRNA stability through the hilD mRNA 3' UTR

Abdulla, S. Z.; Kim, K.; Azam, M. S.; Golubeva, Y. A.; Cakar, F.; Slauch, J. M.; Vanderpool, C. K.

10.1101/2022.09.07.507058 — microbiology — Posted on 2022-09-08

3234 Postpartum estrogen withdrawal induces deficits in affective behaviors and increases ΔFosB in D1 and D2 neurons in the nucleus accumbens core in mice

Foster, W.; Beach, K. F.; Carson, P. F.; Harris, K. C.; Alonso, B. L.; Costa, L. T.; Simamora, R. C.; Corbin, J. E.; Hoag, K. F.; Mercado, S. I.; Bernhard, A. G.; Leung, C. H.; Nestler, E. J.; Been, L. E.

10.1101/2022.09.08.505352 — neuroscience — Posted on 2022-09-08

3235 Cortical Circuit Mechanisms of Multimodal Temporal Pattern Discrimination

Post, S.; Mol, W.; Abu-Wishah, O.; Ali, S.; Rahmatullah, N.; Goel, A.

10.1101/2022.08.31.506133 — neuroscience — Posted on 2022-09-08

3236 Semaphorin signaling restricts neuronal regeneration in C. elegans

Harreguy, M. B.; Shah, E.; Tanvir, Z.; Simprevil, B.; Tran, T. S.; Haspel, G.

10.1101/2021.11.13.468479 — neuroscience — Posted on 2022-09-08

3237 Repeated unilateral handgrip contractions alter functional connectivity and improve contralateral limb response times: A neuroimaging study

Andrushko, J. W.; Levenstein, J. M.; Zich, C.; Edmond, E. C.; Campbell, J.; Clarke, W. T.; Emir, U.; Farthing, J. P.; Stagg, C. J.

10.1101/2021.10.23.464569 — neuroscience — Posted on 2022-09-08

3238 Revealing the Neurobiology Underlying Interpersonal Neural Synchronization with Multimodal Data Fusion

Lotter, L. D.; Kohl, S. H.; Gerloff, C.; Bell, L.; Niephaus, A.; Kruppa, J. A.; Dukart, J.; Schulte-Rüther, M.; Reindl, V.; Konrad, K.

10.1101/2022.07.26.501562 — neuroscience — Posted on 2022-09-08

3239 Hepatic fibrosis induced zinc-deficient dermatosis in American alligators (Alligator mississippiensis)

Piras, I. M.; Bezuidenhout, A.; Diaz-Delgado, J.; Slawski, D.; Kelly, P. A.

10.1101/2022.08.30.505809 — pathology — Posted on 2022-09-08

3240 TP53 mutations in endometrial cancer contribute to clinically-relevant radiation resistance and highlight the potential for biomarker-driven radiosensitization strategies.

Vargas, R.; Petty, A.; Durmaz, A.; Lin-Rahardja, K.; Reizes, O.; Debernardo, R.; Scott, J.

10.1101/2022.09.06.505009 — cancer biology — Posted on 2022-09-08

3241 RFU derived LRs for activity level assignments usingBayesian Networks

Gill, P.; Bleka, O.; Fonnelop, A. E.

10.1101/2021.06.30.450487 — genetics — Posted on 2022-09-08

3242 Adaptive, maladaptive, neutral, or absent plasticity: Hidden caveats of reaction norms

Eriksson, M.; Kinnby, A.; De Wit, P.; Rafajlovic, M.

10.1101/2022.06.21.497038 — evolutionary biology — Posted on 2022-09-08

3243 Spectrin forms a periodic cytoskeleton within the epidermis to preserve axonal integrity.

Coakley, S.; Bonacossa-Pereira, I.; Hilliard, M. A.

10.1101/2022.09.07.507048 — neuroscience — Posted on 2022-09-08

3244 Spinal VGLUT3 lineage neurons drive visceral mechanical allodynia but not visceromotor reflexes

Qi, L.; Lin, S.-h.; Ma, Q.

10.1101/2022.09.07.507044 — neuroscience — Posted on 2022-09-08

3245 A scenario-guided strategy for the future management of biological invasions

10.1101/2022.09.07.506838 — ecology — Posted on 2022-09-08

3246 Statistical Learning of Distractor Suppression Down-regulates Pre-Stimulus Neural Excitability in Early Visual Cortex

Ferrante, O.; Zhigalov, A.; Hickey, C.; Jensen, O.

10.1101/2022.09.07.506943 — neuroscience — Posted on 2022-09-08

3247 PAMR1 negatively impacts cell proliferation and migration of Human Colon Cancer HT29 Cell Line

Haymour, L.; Chaunavel, A.; Diab-Assaf, M.; Maftah, A.; Legardinier, S.

10.1101/2022.09.07.506931 — cancer biology — Posted on 2022-09-08

3248 MOAHIT: A Web Tool for visualizing tumormulti-omics data with human anatomy heatmaps

Zhou, C.; Lin, A.; Zhang, J.; Luo, P.

10.1101/2022.09.07.506938 — bioinformatics — Posted on 2022-09-08

3249 MRI-based computational model generation for cerebral perfusion simulations in health and ischaemic stroke

Jozsa, T. I.; Petr, J.; Barkhof, F.; Payne, S. J.; Mutsaerts, H. J.

10.1101/2022.09.07.506940 — bioengineering — Posted on 2022-09-08

3250 The Phenotype-Genotype Reference Map: Improving biobank data science through replication.

Bastarache, L.; Delozier, S. B.; Pandit, A.; He, J.; Lewis, A.; Annis, A. C.; LeFaive, J.; Denny, J. C.; Carroll, R. J.; Hughey, J. J.; Zawistowski, M.; Peterson, J. F.

10.1101/2022.09.07.506932 — genetics — Posted on 2022-09-08

3251 Higher-order epistasis creates idiosyncrasy, confounding predictions in protein evolution

Buda, K.; Miton, C. M.; Tokuriki, N.

10.1101/2022.09.07.505194 — evolutionary biology — Posted on 2022-09-08

3252 Edge effects constraint endemic but not introduced arthropod species in a pristine forest on Terceira (Azores, Portugal)

Tsafack, N.; Pozsgai, G.; Boieiro, M.; Ros-Prieto, A.; Nunes, R.; Ferreira, M. T.; Borges, P. A. V.

10.1101/2022.09.07.506827 — ecology — Posted on 2022-09-08

3253 Environmental determinants of invasion hotspots and refugia at a river scale: implications for conservation of native biodiversity

Morissette, O.; Charette, C.; Windle, M.; Drouin, A.; Derry, A. M.

10.1101/2022.09.07.506921 — ecology — Posted on 2022-09-08

3254 Food for thought: selectivity for food in human ventral visual cortex

Jain, N.; Wang, A.; Henderson, M. M.; Lin, R.; Prince, J. S.; Tarr, M. J.; Wehbe, L.

10.1101/2022.05.22.492983 — neuroscience — Posted on 2022-09-08

3255 Activation of TrkB in Parvalbumin interneurons is required for the promotion of reversal learning in spatial and fear memory by antidepressants

Jetsonen, E.; Didio, G.; Winkel, F.; Llach Pou, M.; Boj, C.; Kuczynski-Noyau, L.; Voikar, V.; Guirado, R.; Taira, T.; Lauri, S. E.; Castren, E.; Umemori, J.

10.1101/2022.09.07.506934 — neuroscience — Posted on 2022-09-08

3256 On the performance of multi-compartment relaxometry for myelin water imaging - Intra-subject and inter-protocol reproducibility

Chan, K.-S.; Chamberland, M.; Marques, J. P.

10.1101/2022.09.07.506917 — neuroscience — Posted on 2022-09-08

3257 Musleblind-1 regulates microtubule cytoskeleton in C. elegans mechanosensory neuron through tubulin mRNAs

Puri, D.; Samaddar, S.; Banerjee, S.; Ghosh-Roy, A.

10.1101/2022.09.07.506915 — neuroscience — Posted on 2022-09-08

3258 Cardiomyocyte BRAF is a key signalling intermediate in cardiac hypertrophy in mice

Alharbi, H. O.; Hardyman, M. A.; Cull, J. J.; Markou, T.; Cooper, S. T.; Glennon, P. E.; Fuller, S. J.; Sugden, P. H.; Clerk, A.

10.1101/2022.09.07.506723 — physiology — Posted on 2022-09-08

3259 AYUKA: A toolkit for fast viral genotyping using whole genome sequencing.

Guerra-Assuncao, J. A.; Goldstein, R. A.; Breuer, J.

10.1101/2022.09.07.506755 — bioinformatics — Posted on 2022-09-08

3260 Phosphoproteomics data-driven signalling network inference: does it work?

Sriraja, L. O.; Werhli, A.; Petsalaki, E.

10.1101/2022.09.07.506895 — bioinformatics — Posted on 2022-09-08

3261 African swine fever virus - variants on the rise

Forth, J. H.; Calvelage, S.; Fischer, M.; Hellert, J.; Sehl-Ewert, J.; Roszyk, H.; Deutschmann, P.; Reichold, A.; Lange, M.; Thulke, H.-H.; Sauter-Louis, C.; Höper, D.; Mandyhra, S.; Sapachova, M.; Beer, M.; Blome, S.

10.1101/2022.09.07.506908 — genomics — Posted on 2022-09-08

3262 DESIGNING OF CUSTOM BARCODES FOR SEQUENCING ON THE MGI PLATFORM

Bulusheva, I.; Shmitko, A.; Vasiliadis, I.; Suchalko, O.; Syrko, D.; Belova, V.; Korostin, D.

10.1101/2022.09.07.506907 — genomics — Posted on 2022-09-08

3263 What does heritability of Alzheimer's disease represent?

Baker, E. A.; Leonenko, G.; Schmidt, K. M.; Hill, M.; Myers, A. J.; Shoai, M.; de Rojas, I.; Tesi, N.; Holstege, H.; van der Flier, W. M.; Pijnenburg, Y. A. L.; Ruiz, A.; Hardy, J.; van der Lee, S.; Escott-Price, V.

10.1101/2022.09.07.506912 — genetics — Posted on 2022-09-08

3264 Platform-Agnostic CellNet (PACNet) enables cross-study meta-analysis of cell fate engineering protocols

Lo, E. K.; Velazquez, J.; Peng, D.; Kwon, C.; Ebrahimkhani, M.; Cahan, P.

10.1101/2022.09.07.506886 — developmental biology — Posted on 2022-09-08

3265 Theoretical limits on the speed of learning inverse models explain the rate of adaptation in arm reaching tasks

Barradas, V. R.; Koike, Y.; Schweighofer, N.

10.1101/2022.09.07.506913 — neuroscience — Posted on 2022-09-08

3266 Functional MRS studies of GABA and Glutamate/Glx: a systematic review and meta-analysis

Pasanta, D.; He, J. L.; Ford, T. C.; Oeltzschner, G.; Lythgoe, D.; Puts, N. A.

10.1101/2022.09.07.506899 — neuroscience — Posted on 2022-09-08

3267 Natural statistics of head roll: implications for Bayesian inference in spatial orientation

Willemsen, S. C. M. J.; Oostwoud Wijdenes, L.; van Beers, R. J.; Koppen, M.; Medendorp, W. P.

10.1101/2022.09.07.506906 — neuroscience — Posted on 2022-09-08

3268 Differential gene expression analysis and physiological response characteristics of passion fruit (Passiflora edulis) buds under high-temperature stress

wang, H.; Ling, Q.; Fu, X.

10.1101/2022.09.07.506887 — plant biology — Posted on 2022-09-08

3269 Image-based phenomic prediction can provide valuable decision support in wheat breeding

Roth, L.; Fossati, D.; Krähenbühl, P.; Walter, A.; Hund, A.

10.1101/2022.09.07.506898 — physiology — Posted on 2022-09-08

3270 Estimating the effectiveness of control and eradication actions on African swine fever transmission in commercial swine populations in the United States

Sykes, A.; Galvis, J. A.; O'Hara, K. C.; Corzo, C.; Machado, G.

10.1101/2022.09.04.506538 — ecology — Posted on 2022-09-08

3271 Pictorial balance is a bottom-up aesthetic property mediated by eye movements. A theoretical model of a primitive visual operating system could explain balance.

Corwin, D. M.

10.1101/2020.05.26.104687 — neuroscience — Posted on 2022-09-08

3272 Expression of macromolecular organic nitrogen degrading enzymes identifies potential mediators of soil organic N availability to an annual grass

Sieradzki, E. T.; Nuccio, E. E.; Pett-Ridge, J.; Firestone, M. K.

10.1101/2020.12.14.422732 — microbiology — Posted on 2022-09-08

3273 Oncogenic signals prime cancer cells for toxic cell growth during a G1 cell cycle arrest

Foy, R.; Crozier, L.; Pareri, A. U.; Park, B. H.; Saurin, A. T.

10.1101/2022.09.08.506962 — cancer biology — Posted on 2022-09-08

3274 A Unifying Bayesian Framework for Merging X-ray Diffraction Data

Dalton, K. M.; Greisman, J.; Hekstra, D. R.

10.1101/2021.01.05.425510 — biophysics — Posted on 2022-09-08

3275 Extremely sparse models of linkage disequilibrium in ancestrally diverse association studies

Nowbandegani, P. S.; Wohns, A. W.; Ballard, J. L.; Lander, E. S.; Bloemendal, A.; Neale, B. M.; O'Connor, L. J.

10.1101/2022.09.06.506858 — genetics — Posted on 2022-09-08

3276 EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes

Richter, D. J.; Berney, C.; Strassert, J. F. H.; Poh, Y.-P.; Herman, E. K.; Munoz-Gomez, S. A.; Wideman, J. A.; Burki, F.; de Vargas, C.

10.1101/2020.06.30.180687 — evolutionary biology — Posted on 2022-09-08

3277 Associations between brood size, gut microbiome diversity and survival in great tit (Parus major) nestlings

Liukkonen, M.; Hukkanen, M.; Cossin-Sevrin, N.; Stier, A.; Vesterinen, E.; Grond, K.; Ruuskanen, S.

10.1101/2022.09.06.506880 — ecology — Posted on 2022-09-08

3278 Wildfires change plant scents but not pollinator attraction in a Mediterranean palm

Garcia, Y.; Castellanos, M. C.; Pausas, J. G.

10.1101/2022.09.06.506788 — ecology — Posted on 2022-09-08

3279 siRNA-mediated gene knockdown via electroporation in hydrozoan jellyfish embryos

Masuda-Ozawa, T.; Fujita, S.; Nakamura, R.; Watanabe, H.; Kuranaga, E.; Nakajima, Y.-i.

10.1101/2022.03.24.485716 — developmental biology — Posted on 2022-09-08

3280 Atg1 and Marf collaborate to maintain germline stem cells in Drosophila

Ayachit, M.; Shravage, B. V.

10.1101/2022.09.08.507105 — cell biology — Posted on 2022-09-08

3281 The DEPDC1 protein LET-99 is required for cortical stability and antagonizes branched actin formation to promote robust cytokinesis

Price, K. L.; Lamb, H.; Alvarado, J. V.; Rose, L.

10.1101/2022.09.07.506988 — cell biology — Posted on 2022-09-08

3282 Rapidly Inferring Personalized Neurostimulation Parameters with Meta-Learning: A Case Study of Individualized Fiber Recruitment in Vagus Nerve Stimulation

Mao, X.; Chang, Y.-C.; Zanos, S.; Lajoie, G.

10.1101/2022.09.06.506839 — neuroscience — Posted on 2022-09-08

3283 Joint Learning of Full-structure Noise in Hierarchical Bayesian Regression Models

Hashemi, A.; Cai, C.; Gao, Y.; Ghosh, S.; Müller, K.-R.; Nagarajan, S.; Haufe, S.

10.1101/2021.11.28.470264 — neuroscience — Posted on 2022-09-08

3284 Synaptic status differentially regulates neurofilaments in dendritic spines

Guerth, C.-M.; do Rego Barros Fernandes Lima, M. A.; Cereceda Delgado, A. R.; Macarron, V.; Hubrich, J.; D'Este, E.

10.1101/2022.09.07.506909 — neuroscience — Posted on 2022-09-08

3285 Upper limb joint coordination acts to preserve hand kinematics after a traumatic brachial plexus injury

Lustosa, L. A.; Silva, A. E. L.; Carvalho, R. P.; Vargas, C. D.

10.1101/2022.09.06.506862 — neuroscience — Posted on 2022-09-08

3286 A neural framework for spontaneous development of orientation selectivity in the primary visual cortex

Davey, C. E.; Lloyd, E. K. J.; Kuhlmann, L.; Burkitt, A. N.; Vidyasagar, T. R.

10.1101/2022.09.06.505990 — neuroscience — Posted on 2022-09-08

3287 Sex dependence of opioid-mediated responses to subanesthetic ketamine

Di Ianni, T.; Azadian, M. M.; Ewbank, S. N.; Michaelides, M.; Airan, R. D.

10.1101/2022.09.06.506854 — neuroscience — Posted on 2022-09-08

3288 Respiratory strategy at birth initiates distinct lung injury phenotypes in the preterm lamb lung

Pereira-Fantini, P. M.; Ferguson, K.; McCall, K.; Oakley, R.; Perkins, E.; Byars, S. G.; Williamson, N.; Nie, S.; Tingay, D.

10.1101/2022.09.06.506865 — systems biology — Posted on 2022-09-08

3289 Cross-tissue multiomics studies reveal gut-brain interactions mediating the effect of Akkermansia muciniphila in counteracting fructose-induced obesity

Ha, S. M.; Ahn, I.-S.; Kowal-safron, T.; Yoon, J.; Diamante, G.; Cely, I.; Zhang, G.; Wang, S.; Yang, X.

10.1101/2022.09.06.506855 — systems biology — Posted on 2022-09-08

3290 Using ARCADE (ARChaeplastida Annotation DatabasE) to understand the evolution of genome size in land plants

Menezes, A. P. A.; Almeida, J. V. d. A.; Del-Bem, L.-E.; Lobo, F. P.

10.1101/2022.09.06.506765 — plant biology — Posted on 2022-09-08

3291 Transcriptomic analysis of seed development in Paysonia auriculata (Brassicaceae) identifies genes involved in hydroxy fatty acid biosynthesis and seed maturation

Hu, H.; Swift, A.; Mauro-Herrera, M.; Borja, L.; Borrone, J.; Doust, A. N.

10.1101/2022.09.06.506826 — plant biology — Posted on 2022-09-08

3292 DeepVariant calling provides insights into race diversity and its implication for sorghum breeding

Ruperao, P.; Gandham, P.; Odeny, D. A.; Selvanayagam, S.; Thirunavukkarasu, N.; Das, R. R.; Srikanda, M.; Gandhi, H.; Habyarimana, E.; Manyasa, E.; Nebie, B.; Deshpande, S. P.; Rathore, A.

10.1101/2022.09.06.505536 — plant biology — Posted on 2022-09-08

3293 Contact Stiffness Governs Mechanoresponses of Living Cells to Extracellular Microenvironment

Zhao, P.; Zheng, Y.; Zhang, Z. Y.; Jiang, M. W.; Jiang, Y. X.; Du, J.; Cao, Y.

10.1101/2022.09.07.506641 — biophysics — Posted on 2022-09-08

3294 Peptide-PAINT using a transfected-docker enables live- and fixed-cell super-resolution imaging

Maity, B. K.; Nall, D.; Lee, Y.; Selvin, P. R.

10.1101/2022.09.07.507019 — biophysics — Posted on 2022-09-08

3295 Multi-Omics Analysis of Magnetically Levitated Plasma Biomolecules

Ashkarran, A. A.; Gharibi, H.; Zeki, D. A.; Radu, I.; Khalighinejad, F.; Keyhanian, K.; Abrahamsson, C. K.; Ionete, C.; Saei, A. A.; Mahmoudi, M.

10.1101/2022.09.06.506852 — bioengineering — Posted on 2022-09-08

3296 Metabolic trait means but not correlations differ among fungal endophytes isolated from the same plant species

Gluck-Thaler, E.; Shaikh, M.; Wood, C. W.

10.1101/2022.09.06.506840 — evolutionary biology — Posted on 2022-09-08

3297 Cell cycle progression defects and impaired DNA damage signaling drive enlarged cells into senescence

Manohar, S.; Estrada, M. E.; Uliana, F.; Neurohr, G. E.

10.1101/2022.09.08.506740 — cell biology — Posted on 2022-09-08

3298 A time and single-cell resolved model of hematopoiesis

Kucinski, I.; Campos, J.; Barile, M.; Severi, F.; Bohin, N.; Moreira, P. N.; Allen, L.; Lawson, H.; Haltalli, M. L. R.; Kinston, S. J.; O'Carroll, D.; Kranc, K. R.; Göttgens, B.

10.1101/2022.09.07.506735 — cell biology — Posted on 2022-09-08

3299 Actin-driven protrusions generate rapid long-range membrane tension propagation in cells

De Belly, H.; Yan, S.; Borja da Rocha, H.; Ichbiah, S.; Town, J. P.; Turlier, H.; Bustamante, C. J.; Weiner, O. D.

10.1101/2022.09.07.507005 — cell biology — Posted on 2022-09-08

3300 A discrete mode of endosomal GPCR signaling that does not require β-arrestin

Blythe, E. E.; Von Zastrow, M.

10.1101/2022.09.07.506997 — cell biology — Posted on 2022-09-08

3301 Tracking N-and C-termini of C. elegans polycystin-1 reveals their distinct targeting requirements and functions in cilia and extracellular vesicles

Walsh, J. D.; Wang, J.; DeHart, M. T.; Nikonorova, I.; Srinivasan, J.; Barr, M. M.

10.1101/2022.09.07.504996 — cell biology — Posted on 2022-09-08

3302 Cell overgrowth during G1 arrest triggers an osmotic stress response and chronic p38 activation to promote cell cycle exit

Crozier, L.; Foy, R.; Adib, R.; Badonyi, M.; Kar, A.; Holt, J. A.; Wilson, R.; Regnault, C.; Whitfield, P.; Marsh, J. A.; Saurin, A. T.; Barr, A. R.; Ly, T.

10.1101/2022.09.08.506843 — cell biology — Posted on 2022-09-08

3303 Proteomic signatures of the serological response to flu vaccination in a large human cohort study

Wu, S.; Pushalkar, S.; Maity, S.; Pressler, M.; Rendleman, J.; Vitrinel, B.; Carlock, M. A.; Ross, T.; Choi, H.; Vogel, C.

10.1101/2022.09.06.506846 — immunology — Posted on 2022-09-08

3304 GOAT: Deep learning-enhanced Generalized Organoid Annotation Tool

Bremer, J. P.; Baumdick, M. E.; Knorr, M. S.; Wegner, L. H. M.; Wesche, J.; Jordan-Paiz, A.; Jung, J. M.; Highton, A. J.; Jäger, J.; Hinrichs, O.; Brias, S.; Niersch, J.; Müller, L.; Schreurs, R. R. C. E.; Koyro, T.; Löbl, S.; Mensching, L.; Konczalla, L.; Niehrs, A.; Vondran, F. W. R.; Schramm, C.; Hölzemer, A.; Oldhafer, K. J.; Königs, I.; Kluge, S.; Perez, D.; Reinshagen, K.; Pals, S. T.; Gagliani, N.; Joosten, S. P.; Topf, M.; Altfeld, M.; Bunders, M. J.

10.1101/2022.09.06.506648 — bioinformatics — Posted on 2022-09-08

3305 Bayesian optimization for demographic inference

Noskova, E.; Borovitskiy, V.

10.1101/2022.09.06.506809 — bioinformatics — Posted on 2022-09-08

3306 Predicting cell population-specific gene expression from genomic sequence

Michielsen, L.; Reinders, M.; Mahfouz, A.

10.1101/2022.09.06.506837 — bioinformatics — Posted on 2022-09-08

3307 Integrating and formatting biomedical data as pre-calculated knowledge graph embeddings in the Bioteque

Fernandez-Torras, A.; Duran-Frigola, M.; Bertoni, M.; Locatelli, M.; Aloy, P.

10.1101/2022.05.11.491490 — bioinformatics — Posted on 2022-09-08

3308 Avoiding misleading estimates using mtDNA heteroplasmy statistics to study bottleneck size and selection

Giannakis, K.; Broz, A. K.; Sloan, D. B.; Johnston, I.

10.1101/2022.09.06.506828 — genetics — Posted on 2022-09-08

3309 Edaphic controls on genome size and GC content of bacteria in soil microbial communities

Chuckran, P. F.; Flagg, C.; Propster, J.; Rutherford, W. A.; Sieradzki, E. T.; Blazewicz, S. J.; Hungate, B. A.; Pett-Ridge, J. A.; Schwartz, E.; Dijkstra, P.

10.1101/2021.11.17.469016 — ecology — Posted on 2022-09-08

3310 Head and Neck Cancer-derived small extracellular vesicles sensitize TRPV1+ neurons to mediate cancer pain

Inyang, K. E.; Evans, C. M.; Heussner, M.; Petroff, M.; Reimers, M.; Vermer, P. D.; Tykocki, N.; Folger, J. K.; Laumet, G.

10.1101/2022.09.06.506411 — neuroscience — Posted on 2022-09-08

3311 Global remapping in granule cells and mossy cells of the mouse dentate gyrus

Kim, S. H.; GoodSmith, D.; Temme, S. J.; Moriya, F.; Ming, G.-l.; Christian, K.; Song, H.; Knierim, J. J.

10.1101/2022.09.06.506812 — neuroscience — Posted on 2022-09-08

3312 Reactive astrocyte derived extracellular vesicles promote functional repair post stroke

Xin, S.; Phan, N. V.; Zhang, L.; Carmichael, S. T.; Segura, T.

10.1101/2022.09.06.506818 — neuroscience — Posted on 2022-09-08

3313 Visual object topographic motifs emerge from self-organization of a unified representational space

Doshi, F. R.; Konkle, T.

10.1101/2022.09.06.506403 — neuroscience — Posted on 2022-09-08

3314 Vitamin B12 produced by gut bacteria modulates excitatory neurotransmission

Kang, W. K.; Araya, A.; Fox, B. W.; Thackeray, A.; Schroeder, F. C.; Walhout, A. J. M.; Alkema, M. J.

10.1101/2022.09.06.506833 — neuroscience — Posted on 2022-09-08

3315 Heart Is Deceitful Above All Things: illusory perception of heartbeat is induced by pain expectation.

PARROTTA, E.; Bach, P.; Perrucci, M. G.; Costantini, M.; Ferri, F.

10.1101/2022.09.06.505290 — neuroscience — Posted on 2022-09-08

3316 Decoding Attended Spatial Location during Complex Scene Analysis with fNIRS.

Ning, M. H.; Yucel, M.; Boas, D. A.; Luhmann, A. V.; Sen, K.

10.1101/2022.09.06.506821 — bioengineering — Posted on 2022-09-08

3317 Early life adversity and adult social relationships have independent effects on survival in a wild animal model of aging

Lange, E. C.; Zeng, S.; Campos, F. A.; Li, F.; Tung, J.; Archie, E. A.; Alberts, S. C.

10.1101/2022.09.06.506810 — animal behavior and cognition — Posted on 2022-09-08

3318 Deadly and venomous Lonomia caterpillars are more than the two usual suspects

Gonzalez, C.; Ballesteros-Mejia, L.; Diaz-Diaz, J. M.; Toro-Vargas, D. M.; Amarillo-Suarez, A.; Gey, D.; Leon-Ramos, C. M.; Arias, M.; Tovar, E.; Rivera, N.; Buitrago, L. S.; Pinto-Moraes, R. H.; Sano Martins, I. S.; Decaëns, T.; Gonzalez, M. A.; Kitching, I. J.; Rougerie, R.

10.1101/2022.09.06.506776 — ecology — Posted on 2022-09-08

3319 An extracellular vesicle targeting ligand that binds to Arc proteins and facilitates Arc transport in vivo

Lee, P. H.; Anaya, M.; Ladinsky, M. S.; Reitsma, J.; Zinn, K.

10.1101/2022.09.06.506798 — cell biology — Posted on 2022-09-08

3320 The Presence of Myelinated Nerves and Schwann Cells in White Adipose Tissue: Proximity to Synaptic Vesicle Containing Nerve Terminals and Potential Role in BTBR ob/ob Demyelinating Diabetic Neuropathy

Willows, J. W.; Gunsch, G.; Paradi, E.; Blaszkiewicz, M.; Tonniges, J. R.; Pino, M. F.; Smith, S. R.; Sparks, L. M.; Townsend, K. L.

10.1101/2022.08.25.505298 — neuroscience — Posted on 2022-09-08

3321 DeepRetroMoCo: Deep neural network-based Retrospective Motion Correction Algorithm for Spinal Cord functional MRI

Mobarak-Abadi, M.; Mahmoudi-Aznave, A.; Dehghani, H.; Zarei, M.; Vahdat, S.; Doyon, J.; Khatibi, A.

10.1101/2022.09.06.506787 — neuroscience — Posted on 2022-09-08

3322 Bicistronic expression of a high-performance calcium indicator and opsin yields stable, robust cortical expression for holographic two-photon stimulation

LaFosse, P. K.; Zhou, Z.; Friedman, N. G.; Deng, Y.; Akitake, B.; Histed, M. H.

10.1101/2022.09.06.506779 — neuroscience — Posted on 2022-09-08

3323 Behavior shapes retinal motion statistics during natural locomotion

Muller, K. S.; Matthis, J.; Bonnen, K.; Cormack, L. K.; Huk, A.; Hayhoe, M.

10.1101/2022.09.06.506797 — neuroscience — Posted on 2022-09-08

3324 Phase separation-based visualization of protein-protein interactions and kinase activities in plants

Safi, A.; Smagghe, W.; Goncalves, A.; Xu, K.; Fernandez, A. I.; Cappe, B.; Riquet, F.; Mylle, E.; Van Damme, D.; Geelen, D.; De Jaeger, G.; Beeckman, T.; Van Leene, J.; Vanneste, S.

10.1101/2022.09.06.506782 — plant biology — Posted on 2022-09-08

3325 Cystathionine gamma lyase overexpression enhances neovascularization through NAD-dependent mechanisms

Kiesworo, K.; MacArthur, M. R.; Kip, P.; Agius, T.; Macabrey, D.; Lambelet, M.; Hamard, L.; Ozaki, C. K.; Mitchell, J. R.; Deglise, S.; Mitchell, S. J.; Allagnat, F.; Longchamp, A.

10.1101/2022.09.06.506715 — physiology — Posted on 2022-09-08

3326 Fibroblasts generate topographical cues that steer cancer cell migration

Baschieri, F.; Illand, A.; Barbazan, J.; Zajac, O.; Henon, C.; Loew, D.; Dingli, F.; Matic Vignjevic, D.; Leveque-Fort, S.; Montagnac, G.

10.1101/2022.09.06.506801 — cancer biology — Posted on 2022-09-08

3327 A Meta-learning based Graph-Hierarchical Clustering Method for Single Cell RNA-Seq Data

Pan, Z.; Lin, Y.; Zhang, H.; Zeng, Y.; Yu, W.; Yang, Y.

10.1101/2022.09.06.506784 — bioinformatics — Posted on 2022-09-08

3328 Phylogenetic Biodiversity Metrics Should Account for Both Accumulation and Attrition of Evolutionary Heritage

Rosindell, J.; Manson, K.; Gumbs, R.; Pearse, W.; Steel, M.

10.1101/2022.07.16.499419 — evolutionary biology — Posted on 2022-09-08

3329 Reorganizing Niche Architecture Still Preserves Organ Function in the Hair Follicle

Wei, H.; Du, S.; Parksong, J.; Pasolli, H. A.; Regot, S.; Gonzalez, L. E.; Xin, T.; Greco, V.

10.1101/2022.09.06.506764 — developmental biology — Posted on 2022-09-08

3330 High-Frequency Stimulation Does Not Improve Comfort of Transcutaneous Spinal Cord Stimulation

Dalrymple, A. N.; Hooper, C. A.; Kuriakose, M. G.; Capogrosso, M.; Weber, D. J.

10.1101/2022.09.06.506783 — neuroscience — Posted on 2022-09-08

3331 Evolution of schooling propensity in the guppy drives changes in anti-predator behavior that are linked to neuroanatomy

Corral-Lopez, A.; Kotrschal, A.; Szorkovszky, A.; Garate-Olaizola, M.; Herbert-Read, J.; van der Bijl, W.; Romenskyy, M.; Zeng, H.-L.; Buechel, S. D.; Fontrodona-Eslava, A.; Pelckmans, K.; Mank, J. E.; Kolm, N.

10.1101/2022.09.07.506928 — evolutionary biology — Posted on 2022-09-08

3332 Early suppression of excitability in subcortical band heterotopia modifies epileptogenesis in rats

Hardy, D.; Buhler, E.; Suchkov, D.; Vinck, A.; Fortoul, A.; Watrin, F.; Represa, A.; Minlebaev, M.; Manent, J.-B.

10.1101/2022.09.06.506850 — neuroscience — Posted on 2022-09-08

3333 A parabrachial-to-amygdala circuit that determines hemispheric lateralization of somatosensory processing

Allen, H. N.; Chaudhry, S.; Hong, V. M.; Lewter, L. A.; Sinha, G. P.; Carrasquillo, Y.; Taylor, B.; Kolber, B. J.

10.1101/2022.09.06.506763 — neuroscience — Posted on 2022-09-08

3334 Noradrenergic cross-modular reciprocal inhibition within the Locus Coeruleus.

Davy, O.; Perrins, R.; Lavigne, M.; Kremer, E.; Tsaneva-Atanasova, K.; Ashby, M.; Hirschberg, S.; Pickering, A. E.

10.1101/2022.09.07.506929 — neuroscience — Posted on 2022-09-08

3335 Low forces push the maturation of neural precursors into neurons

de Vincentiis, S.; Baggiani, M.; Merighi, F.; Cappello, V.; Lopane, J.; Di Caprio, M.; Costa, M.; Mainardi, M.; Onorati, M.; Raffa, V.

10.1101/2022.09.07.507054 — neuroscience — Posted on 2022-09-08

3336 Cognition through internal models: Mirror neurons as one manifestation of a broader mechanism

Aflalo, T.; Chivukula, S.; Zhang, C.; Rosario, E. R.; Pouratian, N.; Andersen, R. A.

10.1101/2022.09.06.506071 — neuroscience — Posted on 2022-09-08

3337 The genetics of cortical organisation and development: a study of 2,347 neuroimaging phenotypes

Warrier, V.; Stauffer, E.-M.; Huang, Q. Q.; Wigdor, E. M.; Slob, E. A. W.; Seidlitz, J.; Ronan, L.; Valk, S. L.; Mallard, T. T.; Grotzinger, A. D.; Romero-Garcia, R.; Baron-Cohen, S.; Geschwind, D. H.; Lancaster, M.; Murray, G. K.; Gandal, M. J.; Alexander-Bloch, A.; Won, H.; Martin, H. C.; Bullmore, E. T.; Bethlehem, R. A. I.

10.1101/2022.09.08.507084 — neuroscience — Posted on 2022-09-08

3338 A neurocomputational model of the basal ganglia for the analysis of motor deficits after dopaminergic loss in Parkinson's disease

Gigi, I.; Senatore, R.; Marcelli, A.

10.1101/2021.09.24.461656 — neuroscience — Posted on 2022-09-08

3339 FPCountR: Absolute protein quantification using fluorescence measurements

Csibra, E.; Stan, G.-B.

10.1101/2021.12.06.471413 — synthetic biology — Posted on 2022-09-08

3340 Microliter spotting and micro-colony observation: a rapid and simple approach for counting bacterial colony-forming units

Bhuyan, S.; Yadav, M.; Giri, S. J.; Begum, S.; Das, S.; Phukan, A.; Priyadarshani, P.; Sarkar, S.; Jayswal, A.; Kabyashree, K.; Kumar, A.; Mandal, M.; Ray, S. K.

10.1101/2022.01.26.477842 — microbiology — Posted on 2022-09-08

3341 Successfully treating biofilms of extensively drug resistant Klebsiella pneumoniae isolates from hospital patients with N-Acetyl Cysteine

Bhowmik, A.; Chakraborty, S.; Rohit, A.; Chauhan, A.

10.1101/2022.09.07.506922 — microbiology — Posted on 2022-09-08

3342 Multi-omics analysis reveals distinct non-reversion mechanisms of PARPi resistance in BRCA1- versus BRCA2-deficient mammary tumors

Bhin, J.; Paes Dias, M.; Gogola, E.; Rolfs, F.; Piersma, S. R.; de Bruijn, R.; de Ruiter, J.; van den Broek, B.; Duarte, A.; Sol, W.; van der Heijden, I.; Bakker, L.; Kaiponen, T. S.; Lieftink, C.; Morris, B.; Beijersbergen, R. L.; van de Ven, M.; Jimenez, C. R.; Wessels, L. F. A.; Rottenberg, S.; Jonkers, J.

10.1101/2022.09.07.506927 — cancer biology — Posted on 2022-09-07

3343 Exploratory Meta-Analysis of Hypoxic Transcriptomes Using Precise Transcript Reference Sequence Set

Ono, Y.; Bono, H.

10.1101/2022.05.01.489280 — bioinformatics — Posted on 2022-09-08

3344 Cross-amplified Barcodes on Slides for Spatial Transcriptomics Sequencing

Jin, Z.; Yu, N.; Bai, J.; Liu, Z.; Li, H.; Zhang, J.; Liang, C.

10.1101/2022.08.25.504658 — genomics — Posted on 2022-09-08

3345 Confronting population models with experimental microcosm data: from trajectory matching to state-space models

Rosenbaum, B.; Fronhofer, E. A.

10.1101/2021.09.13.460028 — ecology — Posted on 2022-09-08

3346 Evolved bacterial resistance to the chemotherapy gemcitabine modulates its efficacy

Sayin, S.; Rosener, B.; Li, C. G.; Ho, B.; Ponomarova, O.; Ward, D.; Walhout, A. J.; Mitchell, A.

10.1101/2022.09.07.506952 — systems biology — Posted on 2022-09-07

3347 Topical GZ21T inhibits the growth of actinic keratoses in a UVB induced model of skin carcinogenesis

Bordeaux, Z. A.; Choi, J.; Braun, G.; Davis, C.; Marani, M.; Lee, K.; Samuel, C.; Adams, J.; Windom, R.; Kambala, A.; Cornman, H.; Reddy, S. V.; Pollizzi, A.; LU, W.; Oladipo, O. O.; Alphonse, M. P.; West, C. E.; Kwatra, S. G.; Kwatra, M. M.

10.1101/2022.09.07.506864 — cancer biology — Posted on 2022-09-07

3348 Two neuronal peptides encoded from a single transcript regulate mitochondrial complex III in Drosophila

Bosch, J. A.; Ugur, B.; Pichardo-Casas, I.; Rabasco, J.; Escobedo, F.; Zuo, Z.; Brown, B.; Celniker, S.; Sinclair, D.; Bellen, H. J.; Perrimon, N.

10.1101/2020.07.01.182485 — genomics — Posted on 2022-09-07

3349 A CDKN2C retroduplication in Bowhead whales is associated with the evolution of extremely long lifespans and alerted cell cycle dynamics

Vazquez, J. M.; Kraft, M.; Lynch, V. J.

10.1101/2022.09.07.506958 — evolutionary biology — Posted on 2022-09-07

3350 Phase separation of Myc differentially regulates gene transcription

Yang, J.; Chung, C.-I.; Koach, J.; Liu, H.; Zhao, Q.; Yang, X.; Shen, Y.; Weiss, W. A.; Shu, X.

10.1101/2022.06.28.498043 — cell biology — Posted on 2022-09-07

3351 GRAS-1 is a conserved novel regulator of early meiotic chromosome dynamics in C. elegans

Martinez-Garcia, M.; Robles, P.; Skinner, M. W.; Baran, K. A.; Nadarajan, S.; Shin, N.; Silva-Garcia, C. G.; Saito, T. T.; Beese-Sims, S.; Castaner, A.; Pacheco, S.; Martinez-Perez, E.; Jordan, P. W.; Colaiacovo, M. P.

10.1101/2022.09.06.506874 — cell biology — Posted on 2022-09-07

3352 Single-cell Total RNA Miniaturized sequencing (STORM-seq) reveals differentiation trajectories of primary human fallopian tube epithelium

Johnson, B. K.; Rhodes, M.; Wegener, M.; Himadewi, P.; Foy, K.; Schipper, J. L.; Siwicki, R. A.; Rossell, L. L.; Siegwald, E. J.; Chesla, D. W.; Teixeira, J. M.; Sheridan, R. T. C.; Adams, M.; Triche, T. J.; Shen, H.

10.1101/2022.03.14.484332 — molecular biology — Posted on 2022-09-07

3353 Delayed puberty, gonadotropin abnormalities and subfertility in male Padi2/Padi4 double knockout mice

Sams, K. L.; Mukai, C.; Marks, B. A.; Mittal, C.; Demeter, E. A.; Nelissen, S.; Grenier, J. K.; Tate, A. E.; Ahmed, F.; Coonrod, S. A.

10.1101/2022.02.09.479603 — molecular biology — Posted on 2022-09-07

3354 Microliter spotting and micro-colony observation: a rapid and simple approach for counting bacterial colony-forming units

Bhuyan, S.; Yadav, M.; Giri, S. J.; Begum, S.; Das, S.; Phukan, A.; Priyadarshani, P.; Sarkar, S.; Jayswal, A.; Kabyashree, K.; Kumar, A.; Mandal, M.; Ray, S. K.

10.1101/2022.01.26.477842 — microbiology — Posted on 2022-09-07

3355 Microglia protect fungi against copper starvation and promote brain infection

Mohamed, S. H.; Fu, M. S.; Hain, S.; Alselami, A.; Vanhoffelen, E.; Li, Y.; Bojang, E.; Lukande, R.; Ballou, E. R.; May, R. C.; Ding, C.; Vande Velde, G.; Drummond, R. A.

10.1101/2022.09.07.506901 — immunology — Posted on 2022-09-07

3356 A dual function for the chromatin organizer Special A-T rich Binding Protein 1 in B-lineage cells

Thomas, M.; Martin, O.; Bruzeau, C.; Pollet, J.; Bender, S.; Carrion, C.; Le Noir, S.; Pinaud, E.

10.1101/2022.09.06.506747 — immunology — Posted on 2022-09-07

3357 Robust induction of functional astrocytes using NGN2 expression in human pluripotent stem cells

Berryer, M. H.; Tegtmeyer, M.; Binan, L.; Valakh, V.; Nathanson, A.; Trendafilova, D.; Crouse, E.; Klein, J.; Meyer, D.; Pietilainen, O.; Rapino, F.; Farhi, S.; Rubin, L. L.; McCarroll, S.; Nehme, R.; Barrett, L. E.

10.1101/2022.09.07.507028 — neuroscience — Posted on 2022-09-07

3358 A neurocomputational model of the basal ganglia for the analysis of motor deficits after dopaminergic loss in Parkinson's disease

Gigi, I.; Senatore, R.; Marcelli, A.

10.1101/2021.09.24.461656 — neuroscience — Posted on 2022-09-07

3359 Multi-block RNN Autoencoders Enable Broadband ECoG Signal Reconstruction

Nolan, M.; Pesaran, B.; Shlizerman, E.; Orsborn, A. L.

10.1101/2022.09.07.507004 — neuroscience — Posted on 2022-09-07

3360 GDF15 antagonism limits severe heart failure and prevents cardiac cachexia in mice

Takaoka, M.; Tadross, J. A.; Al-Hadithi, A.; Villena-Gutierrez, R.; Tromp, J.; Absar, S.; Au, M.; Harrison, J.; Coll, A. P.; Marciniak, S. J.; Rimmington, D.; Oliver, E.; Ibanez, B.; Voors, A. A.; O'Rahilly, S.; Mallat, Z.; Goodall, J. C.

10.1101/2022.09.06.506633 — pathology — Posted on 2022-09-07

3361 Disruption of the MYC Super-Enhancer Complex by Dual Targeting of FLT3 and LSD1 in Acute Myeloid Leukemia

Yashar, W. M.; Smith, B. M.; Coleman, D. J.; VanCampen, J.; Kong, G.; Macaraeg, J.; Estabrook, J.; Demir, E.; Long, N.; Bottomly, D.; McWeeney, S. K.; Tyner, J. W.; Druker, B. J.; Maxson, J. E.; Braun, T. P.

10.1101/2022.01.17.476469 — cancer biology — Posted on 2022-09-07

3362 A novel cancer-associated cassette exon in TLN1 alters Talin 1 mechanosensitivity

Gallego-Paez, L. M.; Edwards, W. J. S.; Guo, Y.; Chanduri, M.; Koorman, T.; Lee, C.-Y.; Grexa, N.; Derksen, P. W. B.; Yan, J.; Schwartz, M. A.; Mauer, J.; Goult, B. T.

10.1101/2022.09.06.506802 — cancer biology — Posted on 2022-09-07

3363 Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in solid tumors

Monzo, H.; Hyytiäinen, M.; Elbasani, E.; Kalander, K.; Wall, J.; Moyano-Galceran, L.; Tanjore Ramanathan, J.; Jukonen, J.; Laakkonen, P.; Ristimäki, A.; Carlson, J.; Lehti, K.; Salehi, S.; Puolakkainen, P.; Haglund, C.; Seppänen, H.; Leppa, S.; Ojala, P. M.

10.1101/2022.09.02.506335 — cancer biology — Posted on 2022-09-07

3364 Connecting sequence features within the disordered C-terminal linker of B. subtilis FtsZ to function and bacterial cell division

Shinn, M. K.; Cohan, M. C.; Bullock, J. L.; Ruff, K. M.; Levin, P. A.; Pappu, R. V.

10.1101/2022.06.29.498098 — biophysics — Posted on 2022-09-07

3365 Learning epistatic polygenic phenotypes with Boolean interactions

Behr, M.; Kumbier, K.; Cordova-Palomera, A.; Aguirre, M.; Ashley, E.; Butte, A.; Arnaout, R.; Brown, J. B.; Preist, J.; Yu, B.

10.1101/2020.11.24.396846 — bioinformatics — Posted on 2022-09-07

3366 The piRNA cluster torimochi is an expanding transposon in cultured silkworm cells

Shoji, K.; Umemura, Y.; Tomari, Y.

10.1101/2022.09.07.506900 — genomics — Posted on 2022-09-07

3367 Three-dimensional organization of chromatin associated RNAs and their role in chromatin architecture in human cells

Calandrelli, R.; Wen, X.; Charles Richard, J. L.; Luo, Z.; Nguyen, T. C.; Chen, C.-J.; Qi, Z.; Xue, S.; Chen, W.; Yan, Z.; Wu, W.; Zaleta-Rivera, K.; Hu, R.; Yu, M.; Wang, Y.; Li, W.; Ma, J.; Ren, B.; Zhong, S.

10.1101/2021.06.10.447969 — genomics — Posted on 2022-09-07

3368 Innovations in double digest restriction-site associated DNA sequencing (ddRAD-Seq) method for more efficient SNP identification

Magbanua, Z. V.; Hsu, C.-y.; Pechanova, O.; Arick, M.; Grover, C. E.; Peterson, D. G.

10.1101/2022.09.06.506835 — genomics — Posted on 2022-09-07

3369 The Drosophila attP40 docking site and derivatives are insertion mutations of MSP300

van der Graaf, K.; Srivastav, S.; Singh, P.; McNew, J.; Stern, M.

10.1101/2022.05.14.491875 — genetics — Posted on 2022-09-07

3370 Rapid Evolution of Glycan Recognition Receptors Reveals an Axis of Host-Microbe Conflicts at Carbohydrate-Protein Interfaces

Hilbert, Z. A.; Young, H. J.; Schwiesow, M.; Elde, N. C.

10.1101/2022.09.07.507018 — evolutionary biology — Posted on 2022-09-07

3371 A mathematical framework for evo-devo dynamics

Gonzalez-Forero, M.

10.1101/2021.05.17.444499 — evolutionary biology — Posted on 2022-09-07

3372 Islet architecture in adult mice is actively maintained by Robo2 expression in beta cells

Waters, B. J.; Blum, B.

10.1101/2022.09.07.506980 — developmental biology — Posted on 2022-09-07

3373 Epigenetic centromere identity is precisely maintained through DNA replication but is uniquely specified among human cells

Mahlke, M.; Lumerman, L.; Ly, P.; Nechemia-Arbely, Y.

10.1101/2022.09.07.506974 — molecular biology — Posted on 2022-09-07

3374 The Intestinal Microbiome, Dietary Habits, and Physical and Psychological Resilience in Postpartum Women

Matsunaga, M.; Takeuchi, M.; Watanabe, S.; Takeda, A. K.; Kikusui, T.; Mogi, K.; Nagasawa, M.; Hagihara, K.; Myowa, M.

10.1101/2022.09.07.506896 — microbiology — Posted on 2022-09-07

3375 Successfully treating biofilms of extensively drug resistant Klebsiella pneumoniae isolates from hospital patients with N-Acetyl Cysteine

Chauhan, A.; Bhowmik, A.; Rohit, A.

10.1101/2022.09.07.506922 — microbiology — Posted on 2022-09-07

3376 A third SARS-CoV-2 mRNA vaccine dose in people receiving hemodialysis overcomes B cell defects but elicits a skewed CD4+ T cell profile

Sannier, G.; Nicolas, A.; Dube, M.; Marchitto, L.; Nayrac, M.; Tastet, O.; Tauzin, A.; Lima-Barbosa, R.; Laporte, M.; Cloutier, R.; Flores, A. S.; Boutin, M.; Gong, S. Y.; Benlarbi, M.; Ding, S.; Bourassa, C.; Gendron-Lepage, G.; Medjahed, H.; Goyette, G.; Brassard, N.; Ortega-Delgado, G.-G.; Niessl, J.; Gokool, L.; Morrisseau, C.; Arlotto, P.; Rios, N.; Tremblay, C.; Martel-Laferriere, V.; Prat, A.; Belair, J.; Beaubien-Souligny, W.; Goupil, R.; Nadeau-Fredette, A.-C.; Lamarche, C.; Finzi, A.; Suri, R.; Kaufmann, D. E.

10.1101/2022.09.05.506622 — immunology — Posted on 2022-09-07

3377 Third-order motifs are sufficient to fully anduniquely characterize spatiotemporal neuralnetwork activity

Deshpande, S. S.; Smith, G.; van Drongelen, W.

10.1101/2021.08.16.456546 — neuroscience — Posted on 2022-09-07

3378 MultiOMICs landscape of SARS-CoV-2-induced host responses in human lung epithelial cells

Pinto, S. M.; Subbannayya, Y.; Kim, H.; Hagen, L.; Gorna, M. W.; Nieminen, A. I.; Bjoras, M.; Espevik, T.; Kainov, D. E.; Kandasamy, R. K.

10.1101/2022.09.06.506768 — systems biology — Posted on 2022-09-07

3379 Red light-emitting short Mango-based system enables tracking a mycobacterial small noncoding RNA in infected macrophages

Bychenko, O.; Khrulev, A. A.; Svetlova, J. I.; Tsvetkov, V. B.; Kamzeeva, P. N.; Skvortsova, Y.; Tupertsev, B. S.; Ivanov, I. A.; Aseev, L. V.; Khodarovich, Y. M.; Belyaev, E. S.; Kozlovskaya, L. I.; Zatsepin, T. S.; Azhikina, T. L.; Varizhuk, A. M.; Aralov, A. V.

10.1101/2022.09.07.506834 — synthetic biology — Posted on 2022-09-07

3380 Wheat EARLY FLOWERING3 is a dawn-expressed circadian oscillator component that regulates heading date

Wittern, L.; Steed, G.; Taylor, L. J.; Cano Ramirez, D.; Pingarron-Cardenas, G.; Greenland, A.; Gardner, K.; Hannah, M. A.; Webb, A. A. R.

10.1101/2021.09.03.458922 — plant biology — Posted on 2022-09-07

3381 Molecular determinants of dynamic protein-protein interactions in the functional cycle of the membrane protein DsbD

Stelzl, L. S.; Kritsiligkou, P.; Mehdipour, A. R.; Baldwin, A. J.; Ferguson, S. J.; Mavridou, D. A. I.; Sansom, M. S. P.; Redfield, C.

10.1101/2022.09.07.506916 — biophysics — Posted on 2022-09-07

3382 Atomistic Simulations and Network-Based Energetic Profiling of Binding and Allostery in the SARS-CoV-2 Spike Omicron BA.1, BA.1.1, BA.2 and BA.3 Subvariant Complexes with the Host Receptor: Revealing Hidden Functional Roles of the Binding Hotspots in Mediating Epistatic Effects and Long-Range Communication with Allosteric Pockets

Verkhivker, G.; Agajanian, S.; Krishnan, K.; Kassab, R.

10.1101/2022.09.05.506698 — biophysics — Posted on 2022-09-07

3383 Beta-cell Metabolic Activity Rather than Gap Junction Structure Dictates Subpopulations in theIslet Functional Network

Briggs, J. K.; Kravets, V.; Dwulet, J. M.; Albers, D. J.; Benninger, R. K.

10.1101/2022.02.06.479331 — biophysics — Posted on 2022-09-07

3384 CaMKII activity spreads by inter-holoenzyme phosphorylation

Lucic, I.; Heluin, L.; Jiang, P.-L.; Castro Scalise, A. G.; Wang, C.; Franz, A.; Wahl, M.; Liu, F.; Plested, A. J. R.

10.1101/2022.08.03.502606 — biophysics — Posted on 2022-09-07

3385 Automated identification of aneuploid cells within the inner cell mass of an embryo using a numerical extraction of morphological signatures

Habibalahi, A.; Campbell, J. M.; Tan, T.; Mahbub, S. B.; Rose, R.; Mustafa, S.; Dunning, K.; Goldys, E.

10.1101/2022.09.06.506861 — bioinformatics — Posted on 2022-09-07

3386 CIDP: A multi-functional platform for designing CRISPR sgRNAs

Xu, D.; Zhang, J.; Zhao, X.; Jiang, H.; Ma, X.; Pan, W.

10.1101/2022.09.07.506696 — bioinformatics — Posted on 2022-09-07

3387 KMer-Node2Vec: Learning Vector Representations of K-mers from the K-meGraph

Yu, Z.; Yang, Z.; Lan, Q.; Huang, F.; Cai, Y.

10.1101/2022.08.30.505832 — bioinformatics — Posted on 2022-09-07

3388 Genome-wide metabolite quantitative trait loci analysis (mQTL) in red blood cells from volunteer blood donors

Moore, A.; Busch, M. P.; Dziewulska, K.; Francis, R. O.; Hod, E. A.; Zimring, J. C.; D'Alessandro, A.; Page, G. P.

10.1101/2022.09.07.506936 — biochemistry — Posted on 2022-09-07

3389 Protein engineering shows antifreeze activity scales with ice-binding site area

Scholl, C. L.; Davies, P. L.

10.1101/2022.09.07.506985 — biochemistry — Posted on 2022-09-07

3390 Future COVID-19 surges prediction based on SARS-CoV-2 mutations surveillance

Najar, F.; Linde, E.; Murphy, C.; Borin, V.; Wang, H.; Haider, S.; Agarwal, P.

10.1101/2022.09.05.506640 — genomics — Posted on 2022-09-07

3391 The native mussel Mytilus chilensis genome reveals adaptative molecular signatures facing the marine environment.

Gallardo-Escarate, C.; Valenzuela-Munoz, V.; Nunez-Acuna, G.; Valenzuela-Miranda, D.; Tapia, F.; Yevenes, M.; Gajardo, G.; Toro, J. E.; Oyarzun, P. A.; Arriagada, G.; novoa, b.; Figueras, A.; Roberts, S.; Gerdol, M.

10.1101/2022.09.06.506863 — genomics — Posted on 2022-09-07

3392 A CRISPR/Cas9-based enhancement of high-throughput single-cell transcriptomics

Pandey, A. C.; Bezney, J.; DeAscanis, D.; Kirsch, E.; Ahmed, F.; Crinklaw, A.; Choudhary, K. S.; Mandala, T.; Deason, J.; Hamdi, J.; Siddique, A.; Ranganathan, S.; Ordoukhanian, P.; Brown, K.; Armstrong, J.; Head, S.; Topol, E. J.

10.1101/2022.09.06.506867 — genetics — Posted on 2022-09-07

3393 A three-strain synthetic community model whose rapid response to antagonism allows the study of higher-order dynamics and emergent properties in minutes

Aguilar-Salinas, B.; Olmedo-Alvarez, G.

10.1101/2022.09.07.505616 — microbiology — Posted on 2022-09-07

3394 Phagocytosis underpins the biotrophic lifestyle of intracellular parasites in the class Phytomyxea (Rhizaria)

Garvetto, A.; Murua, P.; Kirchmair, M.; Salvenmoser, W.; Hittorf, M.; Ciaghi, S.; Harikrishnan, S. L.; Gachon, C. M. M.; Burns, J. A.; Neuhauser, S.

10.1101/2022.09.07.506935 — microbiology — Posted on 2022-09-07

3395 Antibiotics that affect translation can antagonize phage infectivity by interfering with the deployment of counter-defences.

Pons, B. J.; Dimitriu, T.; Westra, E. R.; van Houte, S.

10.1101/2022.09.07.506948 — microbiology — Posted on 2022-09-07

3396 Fluid flow sensitizes bacterial pathogens to chemical stress

Padron, G. C.; Shuppara, A. M.; Sharma, A.; Koch, M. D.; Palalay, J.-J. S.; Radin, J. N.; Kehl-Fie, T. E.; Imlay, J. A.; Sanfilippo, J. E.

10.1101/2022.09.07.506966 — microbiology — Posted on 2022-09-07

3397 Characterization of TelD, an LXG effector of Streptococcus gallolyticus, antagonized by a non-canonical immunity protein

Teh, W. K.; Ding, Y.; Gubellini, F.; Filloux, A.; Poyart, C.; Dramsi, S.; Givskov, M.

10.1101/2022.09.07.506920 — microbiology — Posted on 2022-09-07

3398 Defining antigen targets to dissect vaccinia virus (VACV) and Monkeypox virus (MPXV)-specific T cell responses in humans

Grifoni, A.; Zhang, Y.; Tarke, A.; Sidney, J.; Rubiro, P.; Reina-Campos, M.; Filaci, G.; Dan, J. M.; Scheuermann, R. H.; Sette, A.

10.1101/2022.09.06.506534 — immunology — Posted on 2022-09-07

3399 Immunogenicity and Protective Efficacy of a SARS-CoV-2 mRNA Vaccine Encoding Secreted Non-Stabilized Spike Protein in Mice

Prompetchara, E.; Ketloy, C.; Alameh, M. G.; Tarakhet, K.; Kaewpang, P.; Yostrerat, N.; Pitakpolrat, P.; Buranapraditkun, S.; Manopwisedcharoen, S.; Thitithanyanont, A.; Jongkaewwattana, A.; Hunsawong, T.; Im-Erbsin, R.; Reed, M.; Wijagkanalan, W.; Patarakul, K.; Palaga, T.; Lam, K.; Heyes, J.; Weissman, D.; Ruxrungtham, K.

10.1101/2022.09.07.506878 — immunology — Posted on 2022-09-07

3400 Combined absence of TRP53 target genes ZMAT3, PUMA and p21 cause a high incidence of cancer in mice

Janic, A.; Strasser, A.; Herold, M.; Brennan, M. S.; Healey, G.; Gangoda, L.; Brinkmann, K.

10.1101/2022.09.06.506741 — cancer biology — Posted on 2022-09-07

3401 Fusion-negative Rhabdomyosarcoma 3D-organoids as an innovative model to predict resistance to cell death inducers

Savary, C.; Huchede, P.; Luciana, L.; Tourbez, A.; Deligne, C.; Picard, C.; Diot, T.; Coquet, C.; Meynard, N.; Le Grand, M.; Tonon, L.; Gadot, N.; Degletagne, C.; Leon, S.; Attignon, V.; Boman, A.; Rochet, I.; Muller, K.; Mournetas, V.; Bergeron, C.; Rinaudo, P.; Dutour, A.; Cordier-Bussat, M.; Dijoud, F.; Corradini, N.; Maucort-Boulch, D.; Pasquier, E.; Blay, J.-Y.; Castets, M.; Broutier, L.

10.1101/2022.09.06.506756 — cancer biology — Posted on 2022-09-07

3402 lncRNA-WAL Promotes Aggressiveness of Triple-Negative Breast Cancer via inducing β-Catenin nuclear translocation.

Huang, H.; Jin, H.; Lei, R.; He, Z.; He, S.; Chen, J.; Saw, P.; Qiu, Z.; Ren, G.; Nie, Y.

10.1101/2022.09.06.506751 — genetics — Posted on 2022-09-07

3403 Long-term retention of antigens in germinal centres is controlled by the spatial organisation of the follicular dendritic cell network

Martinez-Riano, A.; Wang, S.; Boeing, S.; Minoughan, S.; Casal, A.; Spillane, K. M.; Ludewig, B.; Tolar, P.

10.1101/2022.09.06.506650 — immunology — Posted on 2022-09-07

3404 A report card methodology to showcase progress towards threatened species recovery

Ward, M.; Rout, T.; Stewart, R.; Possingham, H.; McDonald-Madden, E.; Clarke, T.; Valentine, L.; Kindler, G.; Macmillan, E.; Watson, J.

10.1101/2022.09.06.506545 — scientific communication and education — Posted on 2022-09-07

3405 Investigating the risk of cardiac fibrosis due to heat-not-burn cigarettes through human cardiac stromal cells

Chimenti, I.; Picchio, V.; Pagano, F.; Carnevale, R.; D'Amico, A.; Cozzolino, C.; Floris, E.; Bordin, A.; Schirone, L.; saade, w.; Miraldi, F.; De Falco, E.; Sciarretta, S.; Peruzzi, M.; Biondi-Zoccai, G.; Frati, G.

10.1101/2022.09.06.506632 — pathology — Posted on 2022-09-07

3406 ETV7 reduces inflammatory responses in breast cancer cells by repressing TNFR1/NF-kappaB axis

Meskyte, E. M.; Pezze, L.; Forcato, M.; Bocci, I. A.; Bisio, A.; Bicciato, S.; Baltriukiene, D.; Ciribilli, Y.

10.1101/2022.09.06.506542 — cancer biology — Posted on 2022-09-07

3407 TP53 mutations in endometrial cancer contribute to clinically-relevant radiation resistance and highlight the potential for biomarker-driven radiosensitization strategies.

Vargas, R.; Petty, A.; Yard, B.; Durmaz, A.; Lin-Rahardja, K.; Scott, J.

10.1101/2022.09.06.505009 — cancer biology — Posted on 2022-09-07

3408 Genome assembly with variable order de Bruijn graphs

Diaz, D.; Salmela, L.; Puglisi, S. J.; Onodera, T.

10.1101/2022.09.06.506758 — bioinformatics — Posted on 2022-09-07

3409 Extending protein interaction networks using proteoforms and small molecules

Hernandez Sanchez, L. F.; Burger, B.; Castro Campos, R. A.; Johansson, S.; Njolstad, P. R.; Barsnes, H.; Vaudel, M.

10.1101/2022.09.06.506730 — bioinformatics — Posted on 2022-09-07

3410 Heritability enrichment in context-specific regulatory networks improves phenotype-relevant tissue identification

Feng, Z.; Duren, Z.; Xin, J.; Yuan, Q.; He, Y.; Su, B.; Wong, W. H.; Wang, Y.

10.1101/2022.09.06.506769 — genetics — Posted on 2022-09-07

3411 Expanding growers' choice of disease management options can promote suboptimal social outcomes

Murray-Watson, R. E.; Cunniffe, N.

10.1101/2022.09.05.506581 — ecology — Posted on 2022-09-07

3412 A double-spiral maze and hi-resolution tracking pipeline to study dispersal by groups of minute insects

Cointe, M.; Burte, V.; Perez, G.; Mailleret, L.; Calcagno, V.

10.1101/2022.09.06.506709 — ecology — Posted on 2022-09-07

3413 Altered visual cortex excitability in premenstrual dysphoric disorder: evidence from magnetoencephalographic gamma oscillations and perceptual suppression

Manyukhina, V. O.; Orekhova, E. V.; Prokofyev, A. O.; Obukhova, T. S.; Stroganova, T. A.

10.1101/2022.09.06.506748 — neuroscience — Posted on 2022-09-07

3414 New forms of ecological knowledge acquisition for freshwater mussels' conservation

Ferreira-Rodriguez, N.

10.1101/2022.09.06.506734 — scientific communication and education — Posted on 2022-09-07

3415 The establishment of Populus x Laccaria bicolor ectomycorrhiza requires the inactivation of MYC2 coordinated defense response with a key role for root terpene synthases

Marques-Galvez, J. E.; Basso, V.; Kohler, A.; Barry, K.; Keymanesh, K.; Johnson, J.; Singan, V.; Grigoriev, I.; Vilgalys, R.; Martin, F.; Veneault-Fourrey, C.

10.1101/2022.09.06.505662 — plant biology — Posted on 2022-09-07

3416 Counting sperm whales and visualising their dive profiles using two-hydrophone recordings and an automated click detector algorithm in a longline depredation context.

Pinson, S.; RICHARD, G.

10.1101/2022.09.06.506716 — animal behavior and cognition — Posted on 2022-09-07

3417 Comparative seasonal abundance and diversity of populations of the Pseudomonas syringae and Soft Rot Pectobacteriaceae species complexes throughout the Durance River catchment from its French Alps sources to its delta

Morris, C. E.; Lacroix, C.; Chandeysson, C.; Guilbaud, C.; Monteil, C.; Piry, S.; Rochelle-Newall, E.; Fiorini, S.; Van Gijsegem, F.; Barny, M.-A.; Berge, O.

10.1101/2022.09.06.506731 — ecology — Posted on 2022-09-07

3418 Initial niche condition determines the aging speed and regenerative activity of quiescent cells

Liu, Q.; Sheng, N.; Zhang, Z.; He, C.; Zhao, Y.; Sun, H.; Chen, J.; Yang, X.; Tang, C.

10.1101/2022.09.06.506737 — cell biology — Posted on 2022-09-07

3419 Mechanisms of mRNA processing defects in inherited THOC6 intellectual disability syndrome

Werren, E. A.; LaForce, G. R.; Srivastava, A.; Perillo, D. R.; Johnson, K.; Berger, B.; Baris, S.; Regan, S. L.; Pfennig, C. D.; de Munnik, S.; Pfundt, R.; Hebbar, M.; Jimenez-Heredia, R.; Karakoc-Aydiner, E.; Ozen, A.; Dmytrus, J.; Krolo, A.; Corning, K.; Prijoles, E.; Louie, R.; Lebel, R.; Le, T.-L.; Gordon, C.; Girish, K. M.; Boztug, K.; Shukla, A.; Bielas, S. L.; Schaffer, A. E.

10.1101/2022.09.06.506502 — molecular biology — Posted on 2022-09-07

3420 Cryo-EM structure of the type III-E CRISPR-Cas effector gRAMP in complex with TPR-CHAT

Huang, Z.; Wang, S.; Guo, M.; Zhu, Y.

10.1101/2022.09.07.506877 — biochemistry — Posted on 2022-09-07

3421 Calcium binding and permeation in TRPV channels: insights from molecular dynamics simulations

Liu, C.; Song, C.

10.1101/2022.09.07.506889 — biophysics — Posted on 2022-09-07

3422 Bridging global actin network patterns to local molecular dynamics: a combined modeling and machine learning framework

Rostami, M. W.; Bannish, B. E.; Gasior, K.; Pinals, R. L.; Copos, C.; Dawes, A. T.

10.1101/2022.09.06.506753 — biophysics — Posted on 2022-09-07

3423 Nano-scale solution of the Poisson-Nernst-Planck (PNP) equations in a fraction of two neighboring cells reveals the magnitude of intercellular electrochemical waves

Jaeger, K. H.; Ivanovic, E.; Kucera, J. P.; Tveito, A.

10.1101/2022.09.07.506904 — biophysics — Posted on 2022-09-07

3424 Head-direction tracks internally directed selective attention in visual working memory

Thom, J. L.; Nobre, A. C.; van Ede, F.; Draschkow, D.

10.1101/2022.05.04.490654 — animal behavior and cognition — Posted on 2022-09-07

3425 Global Phylogeny of the Brassicaceae Provides Important Insights into Gene Discordance

Hendriks, K. P.; Kiefer, C.; Al-Shehbaz, I. A.; Bailey, C. D.; Hooft van Huysduynen, A. A. C.; Nikolov, L.; Nauheimer, L.; Zuntini, A. R.; German, D. A.; Franzke, A.; Koch, M. A.; Lysak, M. A.; Toro-Nunez, O.; Ozudogru, B.; Invernon, V. R.; Walden, N.; Maurin, O.; Hay, N.; Sushkov, P.; Mandakova, T.; Thulin, M.; Windham, M.; Resetnik, I.; Spaniel, S.; Ly, E.; Pires, J. C.; Harkess, A.; Neuffer, B.; Vogt, R.; Braeuchler, C.; Rainer, H.; Janssens, S.; Schmull, M.; Forrest, A.; Guggisberg, A.; Zmarzty, S.; Lepschi, B.; Scarlett, N.; Stauffer, F. W.; Schonberger, I.; Heenan, P.; Baker, W. J.; Fore

10.1101/2022.09.01.506188 — evolutionary biology — Posted on 2022-09-07

3426 Rapid and accurate discrimination of Mycobacterium abscessus subspecies based on matrix-assisted laser desorption ionization-time of flight spectrum and machine learning

Wang, H.-Y.; Kuo, C.-H.; Chung, C.-R.; Lin, T.-W.; Yu, J.-R.; Lu, J.-J.; Wu, T.-S.

10.1101/2022.09.06.506122 — microbiology — Posted on 2022-09-07

3427 High-risk microbial signatures are associated with severe parasitemia in controlled Plasmodium infections of both humans and rhesus macaques

Gustin, A. T.; Broedlow, C. A.; Coronado, E.; Wangari, S.; Iwayama, N.; Ahrens, C. Y.; Garrison, W. D.; Guerriero, K. A.; De Paris, K.; Gale, M.; Klatt, N. R.; Kublin, J. G.; Manuzak, J. A.

10.1101/2022.09.06.506695 — microbiology — Posted on 2022-09-07

3428 Enterococcal linear plasmids adapt to Enterococcus faecium and spread within multidrug-resistant clades.

Hashimoto, Y.; Suzuki, M.; Kobayashi, S.; Hirahara, Y.; Nomura, T.; Kurushima, J.; Hirakawa, H.; Tanimoto, K.; Tomita, H.

10.1101/2022.09.07.506885 — microbiology — Posted on 2022-09-07

3429 Organic Convolution Model of Ventral Visual Path Reproduces Curvature Selective Shape Tuning Found in Area V4

Gold, C. S.

10.1101/2022.05.03.490165 — neuroscience — Posted on 2022-09-07

3430 High resolution analysis of the cytosolic Ca2+ events in beta cell collectives in situ

Postic, S.; Sarikas, S.; Pfabe, J.; Pohorec, V.; Krizancic Bombek, L.; Sluga, N.; Skelin Klemen, M.; Dolensek, J.; Korosak, D.; Stozer, A.; Evans-Molina, C.; Johnson, J. D.; Slak Rupnik, M.

10.1101/2021.04.14.439796 — physiology — Posted on 2022-09-07

3431 Discovery of an alternate mechanism for the inhibition of particulate guanylyl cyclases by the natriuretic peptide 'clearance' receptor

Liu, D.; Ceddia, R. P.; Zhang, W.; Fang, H.; Collins, S. P.

10.1101/2022.09.06.506848 — biochemistry — Posted on 2022-09-07

3432 Coronary artery established through amniote evolution

Mizukami, K.; Higashiyama, H.; Arima, Y.; Ando, K.; Fukuhara, S.; Miyagawa-Tomita, S.; Kurihara, H.

10.1101/2022.09.06.506796 — evolutionary biology — Posted on 2022-09-07

3433 Adaptive and neutral processes that select on life course diversification

Steiner, U. K.; Tuljapurkar, S. D.

10.1101/2022.09.06.506771 — evolutionary biology — Posted on 2022-09-07

3434 Genomic loss of the HSP70cA gene in the vertebrate lineage

Merchant, A.; Ramirez, B. I.; Reyes, M. N.; Van, D.; Martinez-Colin, M.; Ojo, D. O.; Mazuca, E. L.; De La O, H. J.; Glenn, A. M.; Lira, C. G.; Ehsan, H.; Yu, E.; Kaneko, G.

10.1101/2022.09.06.506793 — evolutionary biology — Posted on 2022-09-07

3435 Synteny identifies reliable orthologs for phylogenomics and comparative genomics of the Brassicaceae

Walden, N.; Schranz, M. E.

10.1101/2022.09.07.506897 — evolutionary biology — Posted on 2022-09-07

3436 Wolbachia genomics support a tripartite nutritional symbiosis in blood-sucking Triatomine bugs

Filee, J.; Agesilas-Lequeux, K.; Lacquehay, L.; Berenger, J. M.; Dupont, L.; Mendonca, V.; Aristeu da Rosa, J.; Harry, M.

10.1101/2022.09.06.506778 — evolutionary biology — Posted on 2022-09-07

3437 Flexible communication between cell assemblies and 'reader' neurons

Boucly, C. J.; Pompili, M. N.; Todorova, R.; Leroux, E. M.; Wiener, S.; Zugaro, M.

10.1101/2022.09.06.506754 — neuroscience — Posted on 2022-09-07

3438 Motor Cortex Projections To Red Nucleus And Pons Have Distinct Functional Roles In The Mouse

Lopez-Virgen, V.; Macias, M.; Rodriguez-Moreno, P.; Olivares-Moreno, R.; de Lafuente, V.; Concha, L.; Rojas-Piloni, G.

10.1101/2022.09.06.506669 — neuroscience — Posted on 2022-09-07

3439 Neuronal representation of a working memory-based decision strategy in the motor and prefrontal cortico-basal ganglia loops

Yoshizawa, T.; Ito, M.; Doya, K.

10.1101/2022.09.07.506894 — neuroscience — Posted on 2022-09-07

3440 Activation of the fear-responsive anterior hypothalamic area promotes avoidance and triggers compulsive grooming behavior in mice

Laing, B. T.; Anderson, M. S.; Jayan, A.; Park, A. S.; Erbaugh, L. J.; Solis, O.; Wilson, D. J.; Michaelides, M.; Aponte, Y.

10.1101/2022.09.06.506804 — neuroscience — Posted on 2022-09-07

3441 Many but not all deep neural network audio models capture brain responses and exhibit hierarchical region correspondence

Tuckute, G.; Feather, J.; Boebinger, D.; McDermott, J. H.

10.1101/2022.09.06.506680 — neuroscience — Posted on 2022-09-07

3442 Estimation of the firing behaviour of a complete motoneuron pool by combining EMG signal decomposition and realistic motoneuron modelling

Caillet, A. H.; Phillips, A. T. M.; Farina, D.; Modenese, L.

10.1101/2022.02.21.481337 — neuroscience — Posted on 2022-09-07

3443 Clinically oriented prediction of patient response to targeted and immunotherapies from the tumor transcriptome

Dinstag, G.; Shulman, E. D.; Elis, E.; Ben-Zvi, D. S.; Tirosh, O.; Maimon, E.; Meilijson, I.; Elalouf, E.; Temkin, B.; Vitkovsky, P.; Schiff, E.; Hoang, D.-T.; Sinha, S.; Nair, N. U.; Sang Lee, J.; Schaffer, A. A.; Ronai, Z.; Juric, D.; Apolo, A. B.; Dahut, W. L.; Lipkowitz, S.; Berger, R.; Kurzrock, R.; Papanicolau-Sengos, A.; Karzai, F.; Gilbert, M. R.; Aldape, K.; Rajagopal, P. S.; Beker, T.; Ruppin, E.; Aharonov, R.

10.1101/2022.02.27.481627 — bioinformatics — Posted on 2022-09-06

3444 Molecular characterization of the intact muscle spindle using a multi-omics approach

Bornstein, B.; Heinemann-Yerushalmi, L.; Krief, S.; Adler, R.; Dassa, B.; Leshkowitz, D.; Kim, M.; Bewick, G.; Banks, R. W.; Zelzer, E.

10.1101/2022.07.13.499888 — developmental biology — Posted on 2022-09-06

3445 Profile likelihood-based parameter and predictive interval analysis guides model choice for ecological population dynamics

Simpson, M. J.; Walker, S. A.; Studerus, E. N.; Murphy, R. J.; McCue, S.; Maclaren, O.

10.1101/2022.09.05.506701 — ecology — Posted on 2022-09-06

3446 Dissecting errors made in response to externally- and internally- driven visual tasks in the common marmosets and humans

Amly, W.; Chen, C.-Y.; Onoe, H.; Isa, T.

10.1101/2021.08.29.458139 — neuroscience — Posted on 2022-09-06

3447 Predicting predator-prey interactions in terrestrial endotherms using random forest

Llewelyn, J.; Strona, G.; Dickman, C. R.; Greenville, A.; Wardle, G.; Lee, M. S. Y.; Doherty, S.; Shabani, F.; Saltre, F.; Bradshaw, C. J. A.

10.1101/2022.09.02.506446 — ecology — Posted on 2022-09-06

3448 Di-valent siRNA Mediated Silencing of MSH3 Blocks Somatic Repeat Expansion in Mouse Models of Huntington's Disease

O'Reilly, D.; Belgrad, J.; Ferguson, C.; Summers, A.; Sapp, E.; McHugh, C.; Mathews, E.; Buchwald, J.; Ly, S.; Echeverria Moreno, D.; Kennedy, Z.; Hariharan, V.; Monopoli, K.; Yang, X.; Carroll, J.; Difiglia, M.; Aronin, N.; Khvorova, A.

10.1101/2022.09.06.506795 — molecular biology — Posted on 2022-09-06

3449 Viral infection impacts the 3D subcellular structure of the abundant marine diatom Guinardia delicatula

Walde, M.; Camplong, C.; de Vargas, C.; Baudoux, A.-C.; Simon, N.

10.1101/2022.09.06.505714 — microbiology — Posted on 2022-09-06

3450 Corticostriatal Beta Power Changes Associated with Cognitive Function in Parkinsons Disease

Paulo, D. L.; Qian, H.; Subramanian, D.; Johnson, G. W.; Hett, K.; Kao, C.; Roy, N.; Dhima, K.; Claassen, D. O.; Bick, S. K.

10.1101/2022.07.07.499165 — neuroscience — Posted on 2022-09-06

3451 Climate change has affected the spillover risk of bat-borne pathogens

Van de Vuurst, P.; Qiao, H.; Soler-Tovar, D.; Escobar, L. E.

10.1101/2022.09.06.506814 — systems biology — Posted on 2022-09-06

3452 A novel cancer-associated cassette exon in TLN1 alters Talin 1 mechanosensitivity

Gallego-Paez, L. M.; Edwards, W. J. S.; Guo, Y.; Chanduri, M.; Koorman, T.; Lee, C.-Y.; Grexa, N.; Derksen, P. W. B.; Yan, J.; Schwartz, M. A.; Mauer, J.; Goult, B. T.

10.1101/2022.09.06.506802 — cancer biology — Posted on 2022-09-06

3453 The high-resolution in vivo measurement of replication fork velocity and pausing by lag-time analysis

Huang, D.; Johnson, A. E.; Sim, B. S.; Lo, T.; Merrikh, H.; Wiggins, P. A.

10.1101/2022.08.13.503874 — biophysics — Posted on 2022-09-06

3454 Development and application of a computable genotype model in the GA4GH Variation Representation Specification

Goar, W.; Babb, L.; Chamala, S.; Cline, M.; Freimuth, R. R.; Hart, R. K.; Kuzma, K.; Lee, J.; Nelson, T.; Prlic, A.; Riehle, K.; Smith, A.; Stahl, K.; Yates, A. D.; Rehm, H. L.; Wagner, A. H.

10.1101/2022.09.06.506817 — bioinformatics — Posted on 2022-09-06

3455 Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Bourque, K.; Jones-Tabah, J.; Petrin, D.; Martin, R. D.; Hebert, T.

10.1101/2022.09.06.506781 — biochemistry — Posted on 2022-09-06

3456 Effective use of genetically-encoded optical biosensors for profiling signalling signatures in iPSC-CMs derived from idiopathic dilated cardiomyopathy patients

Bourque, K.; Derish, I.; Hawey, C.; Jones-Tabah, J.; Khan, K.; Alim, K.; Jiang, A.; Sadighian, H.; Zwaig, J.; Gendron, N.; Cecere, R.; Giannetti, N.; Hebert, T.

10.1101/2022.09.06.506800 — biochemistry — Posted on 2022-09-06

3457 Noninvasive, low-cost RNA-sequencing enhances discovery potential of transcriptome studies

Martorella, M.; Kasela, S.; Garcia-Flores, R.; Gokden, A.; Castel, S. E.; Lappalainen, T.

10.1101/2022.09.06.506813 — genomics — Posted on 2022-09-06

3458 An RNA binding module of SWI/SNF is required for activation of cell-type specific enhancers and super-enhancers in early development

Bartholomew, B.; Saha, D.; Animireddy, S.; Lee, J.; Lin, Y.-c.; Feola, K.; Jain, A. K.; Lue, Y.; Liu, B.

10.1101/2022.09.06.506785 — genomics — Posted on 2022-09-06

3459 Generation of floxed alleles for cell-specific knockout in zebrafish

Shin, M.; Nozaki, T.; Toles, B.; Kolb, A.; Luk, K.; Isogai, S.; Ishida, K.; Hanasaka, T.; Parsons, M. J.; Wolfe, S. A.; Lawson, N. D.

10.1101/2022.09.06.506849 — genetics — Posted on 2022-09-06

3460 Msh2-Msh3 interferes with DNA metabolism in vivo

Medina-Rivera, M.; Sridharan, M.; Becker, J.; Phelps, S.; Lamb, N. A.; Kumar, C.; Cornaire, M.; Sutton, M. D.; Bielinsky, A. K.; Balakrishnan, L.; Surtees, J. A.

10.1101/2022.09.06.506750 — genetics — Posted on 2022-09-06

3461 Deregulations of miR-1 and its target Multiplexin promote dilated cardiomyopathy associated with myotonic dystrophy type 1

Souidi, A.; Nakamori, M.; Zmojdzian, M.; Jagla, T.; Renaud, Y.; Jagla, K.

10.1101/2022.09.06.506816 — genetics — Posted on 2022-09-06

3462 One-step generation of a conditional allele in mice using a short artificial intron

Cassidy, A. M.; Thomas, D. B.; Kuliyev, E.; Chen, H.; Pelletier, S.

10.1101/2022.09.06.506831 — genetics — Posted on 2022-09-06

3463 D-mannose ameliorates age-associated cellular senescence in the bladder urothelium and NLRP3/Gasdermin/IL-1β -driven pyroptotic epithelial cell shedding

Joshi, C. S.; Salazar, A. M.; Wang, C.; Ligon, M. M.; Chappidi, R. R.; Fashemi, B. E.; Felder, P. A.; Mora, A.; Grimm, S. L.; Coarfa, C.; Mysorekar, I. U.

10.1101/2022.09.06.506836 — cell biology — Posted on 2022-09-06

3464 Redefining normal breast cell populations using long noncoding RNAs

Bitar, M.; Rivera, I. S.; Pimentel de Almeida, I.; Shi, W.; Ferguson, K.; Beesley, J.; Lakhani, S.; Edwards, S.; French, J. D.

10.1101/2022.09.06.506112 — cell biology — Posted on 2022-09-06

3465 Targeted insertion of reporter transgene into a gene safe harbor in human blood fluke, Schistosoma mansoni

Tanno, W. I.; Moscheid, M. F.; Chaparro, C.; Mann, V. H.; Quack, T.; Rodpai, R.; Miller, A. N.; Wistiphongpun, P.; Buakaew, W.; Mentink-Kane, M.; Miller, L.; Schmid, S.; Popratiloff, A.; Grevelding, C.; Grunau, C.; Brindley, P. J.

10.1101/2022.09.02.506379 — molecular biology — Posted on 2022-09-06

3466 Heterologous boost with mRNA vaccines against SARS-CoV-2 Delta/Omicron variants following an inactivated whole-virus vaccine

10.1101/2022.09.06.506714 — molecular biology — Posted on 2022-09-06

3467 Single-molecule identification of the target RNAs of different RNA binding proteins simultaneously in cells

Flamand, M. N.; Ke, K.; Tamming, R.; Meyer, K.

10.1101/2022.09.06.506842 — molecular biology — Posted on 2022-09-06

3468 Real-time visualisation of conjugation reveals the molecular strategy evolved by the conjugative F plasmid to ensure the sequential production of plasmid factors during establishment in the new host cell

Couturier, A.; Virolle, C.; goldlust, K.; Berne-Dedieu, A.; Reuter, A.; Nolivos, S.; Yamaichi, Y.; Bigot, S.; Lesterlin, C.

10.1101/2022.09.06.506729 — microbiology — Posted on 2022-09-06

3469 Quantitative physiology and proteome adaptations of Bifidobacterium breve NRBB57 at near-zero growth rates

Ortiz Camargo, A. R.; van Mastrigt, O.; Bongers, R.; BenAmor, K.; Knol, J.; Abee, T.; Smid, E. J.

10.1101/2022.09.06.506712 — microbiology — Posted on 2022-09-06

3470 Coordinated and distinct LD-transpeptidase-independent roles of peptidoglycan carboxypeptidases DacC and DacA in stress adaptation and cell shape maintenance

Choi, U.; Park, S. H.; Lee, H. B.; Lee, C.-R.

10.1101/2022.09.06.506770 — microbiology — Posted on 2022-09-06

3471 Immune dynamics at single cell protein level after delta/omicron infection in COVID-19 vaccinated convalescent individuals

Bajaj, R.; Yang, Z.; Hammer, V.; Poeschel, S.; Beiber, K.; Salker, M. S.; Casadei, N.; Ossowski, S.; Riess, O.; Singh, Y.

10.1101/2022.09.05.506626 — immunology — Posted on 2022-09-06

3472 CRISPR screens in 3D assembloids reveal disease genes associated with human interneuron development

Meng, X.; Yao, D.; Kelley, K. W.; Reis, N.; Thete, M. V.; Kulkarni, S.; Bassik, M. C.; Pasca, S. P.

10.1101/2022.09.06.506845 — neuroscience — Posted on 2022-09-06

3473 GDF15 antagonism limits severe heart failure and prevents cardiac cachexia in mice

10.1101/2022.09.06.506633 — pathology — Posted on 2022-09-06

3474 HDAC1 overexpression alters GTPase activity impacting chemoresistance in pancreatic cancer

Wright, C. A.; Gordon, E. R.; Cooper, S. J.

10.1101/2022.09.06.506214 — cancer biology — Posted on 2022-09-06

3475 Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening

Hayat, A.; Carter, E.; King, H. W.; Ors, A.; Doe, A.; Teijeiro, S. A.; Charrot, S.; Godinho, S.; Cutillas, P. R.; Mohammed, H.; Grose, R. P.; Ficz, G.

10.1101/2022.09.06.506760 — cancer biology — Posted on 2022-09-06

3476 Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability

Lu, Y.; Cho, T.; Mukherjee, S.; Malik, A. A.; Gonzalez-Foutel, N.; Suarez, C. F.; Derovic, D.; Oh, R. H.; Langille, E.; Al-Zahrani, K.; Lin, Z.; Tsai, R.; Rotter, V.; Ashton-Prolla, P.; Chemes, L. B.; Moffat, J.; Gingras, A.-C.; Oren, M.; Durocher, D.; Schramek, D.

10.1101/2022.03.13.483372 — cancer biology — Posted on 2022-09-06

3477 Genetic depletion of de novo coenzyme A biosynthesis exacerbates puromycin toxicity

Khadka, S.; Chatoff, A.; Snyder, N. W.; DePinho, R. A.; Muller, F. L.

10.1101/2022.09.06.506844 — cancer biology — Posted on 2022-09-06

3478 Cardiovascular Hemodynamics in Mice with Tumor Necrosis Factor Receptor - Associated Factor 2 Mediated Cytoprotection in the Heart

Marshall, A. G.; Neikirk, K.; Vue, Z.; Beasley, H. K.; Garza-Lopez, E.; Vang, L.; Barongan, T.; Evans, Z.; Anudokem, J.; Pham, T. T.; Gomez, J. A.; Exil, V.; Dai, D.-F.; Entman, M. L.; Taffet, G. E.; Hinton, A.; Reddy, A. K.

10.1101/2022.09.03.506447 — biophysics — Posted on 2022-09-06

3479 CALANGO: a phylogeny-aware comparative genomics tool for discovering quantitative genotype-phenotype associations across species

Hongo, J. A.; de Castro, G. M.; Menezes, A. P. A.; Rios Picorelli, A. C.; Martins da Silva, T. T.; Imada, E. L.; Marchionni, L.; Del-Bem, L.-E.; Chaves, A. V.; Almeida, G.; Campelo, F.; Pereira Lobo, F.

10.1101/2021.08.25.457574 — bioinformatics — Posted on 2022-09-06

3480 Comparing the signaling and transcriptome profiling landscapes of human iPSC-derived and primary rat neonatal cardiomyocytes

Bourque, K.; Jones-Tabah, J.; Petrin, D.; Martin, R. D.; Hebert, T.

10.1101/2022.09.06.506781 — biochemistry — Posted on 2022-09-06

3481 Effective use of genetically-encoded optical biosensors for profiling signalling signatures in iPSC-CMs derived from idiopathic dilated cardiomyopathy patients

Bourque, K.; Derish, I.; Hawey, C.; Jones-Tabah, J.; Khan, K.; Alim, K.; Jiang, A.; Sadighian, H.; Zwaig, J.; Gendron, N.; Cecere, R.; Giannetti, N.; Hebert, T.

10.1101/2022.09.06.506800 — biochemistry — Posted on 2022-09-06

3482 The effects of de novo mutation on gene expression and the consequences for fitness in Chlamydomonas reinhardtii.

Balogun, E.; Ness, R.

10.1101/2022.09.06.506807 — genomics — Posted on 2022-09-06

3483 A single cell atlas of the cycling murine ovary

Morris, M. E.; Meinsohn, M.-C.; Chauvin, M.; Saatcioglu, H. D.; Kashiwagi, A.; Sicher, N. A.; Nguyen, N.; Yuan, S.; Stavely, R. G.; Hyun, M.; Donahoe, P. K.; Sabatini, B. L.; Pepin, D.

10.1101/2022.02.08.479522 — developmental biology — Posted on 2022-09-06

3484 Single molecule co-occupancy of RNA-binding proteins with an evolved RNA deaminase

Lin, Y.; Kwok, S.; Thai, B. Q.; Alabi, Y.; Ostrowski, M.; Wu, K.; Floor, S. N.

10.1101/2022.09.06.506853 — molecular biology — Posted on 2022-09-06

3485 Resistance of SARS-CoV-2 Omicron Subvariant BA.4.6 to Antibody Neutralization

Wang, Q.; Li, Z.; Ho, J.; Guo, Y.; Yeh, A. Y.; Liu, M.; Wang, M.; Yu, J.; Sheng, Z.; Liu, L.; Ho, D. D.

10.1101/2022.09.05.506628 — microbiology — Posted on 2022-09-06

3486 Predicting bioactivity of antibiotic metabolites by molecular docking and dynamics

Chio, H.; Guest, E. E.; Hobman, J. L.; Dottorini, T.; Hirst, J. D.; Stekel, D. J.

10.1101/2022.09.06.506739 — microbiology — Posted on 2022-09-06

3487 Omicron-induced interferon signalling prevents influenza A virus infection

Bojkova, D.; Bechtel, M.; Rothenburger, T.; Kandler, J. D.; Hayes, L.; Olmer, R.; Martin, U.; Jonigk, D.; Ciesek, S.; Wass, M. N.; Michaelis, M.; Cinatl, J.

10.1101/2022.09.06.506799 — microbiology — Posted on 2022-09-06

3488 Controllable self-replicating RNA vaccine delivered intradermally elicits predominantly cellular immunity

Amano, T.; Yu, H.; Amano, M.; Leyder, E.; Badiola, M.; Ray, P.; Kim, J.; Ko, A. C.; Achour, A.; Weng, N.-p.; Kochba, E.; Levin, Y.; Ko, M. S. H.

10.1101/2022.09.05.506686 — immunology — Posted on 2022-09-06

3489 KLC4 shapes axon arbors during development and mediates adult behavior

Haynes, E. M.; Burnett, K. H.; He, J.; Jean-Pierre, M.; Jarzyna, M.; Eliceiri, K. W.; Huisken, J.; Halloran, M.

10.1101/2021.09.26.461872 — neuroscience — Posted on 2022-09-06

3490 A Principal Odor Map Unifies Diverse Tasks in Human Olfactory Perception

Lee, B. K.; Mayhew, E. J.; Sanchez-Lengeling, B.; Wei, J. N.; Qian, W. W.; Little, K.; Andres, M.; Nguyen, B. B.; Moloy, T.; Parker, J. K.; Gerkin, R. C.; Mainland, J. D.; Wiltschko, A. B.

10.1101/2022.09.01.504602 — neuroscience — Posted on 2022-09-06

3491 The Alzheimer risk factor CD2AP causes dysfunction of the brain vascular network

Vandal, M.; Institoris, A.; Korin, B.; Gunn, C.; Lee, S.; Lee, J.; Bourassa, P.; Mishra, R. C.; Peringod, G.; Jiang, Y.; Hirai, S.; Belzil, C.; Reveret, L.; Tremblay, C.; Hashem, M.; Elias, E.; Meilandt, W.; Foreman, O.; Rouse-Girma, M.; Muruve, D.; Nicola, W.; Korbelin, J.; Dunn, J. F.; Braun, A. P.; Bennett, D. A.; Gordon, G. R.; Calon, F.; Shaw, A. S.; Nguyen, M. D.

10.1101/2020.12.10.419598 — neuroscience — Posted on 2022-09-06

3492 Pump-less, recirculating organ-on-a-chip (rOoC) platform

Busek, M.; Aizenshtadt, A.; Koch, T.; Frank, A.; Delon, L.; Amirola-Martinez, M.; Golovin, A.; Dumas, C.; Stokowiec, J.; Gruenzner, S.; Melum, E.; Krauss, S.

10.1101/2022.09.06.506239 — bioengineering — Posted on 2022-09-06

3493 Co-substrate pools can constrain and regulate pathway fluxes in cell metabolism

West, R.; Delattre, H.; Noor, E.; Feliu, E.; Soyer, O. S.

10.1101/2022.09.05.506656 — systems biology — Posted on 2022-09-06

3494 First detection of Ixodiphagus hookeri (Hymenoptera: Encyrtidae) in Ixodes ricinus ticks (Acari: Ixodidae) from multiple locations of Hungary

Toth, A. G.; Farkas, R.; Gyurkovszky, M.; Kriko, E.; Solymosi, N.

10.1101/2022.09.05.506604 — genomics — Posted on 2022-09-06

3495 Bayesian inference of admixture graphs on Native American and Arctic populations

Nielsen, S. V.; Vaughn, A.; Leppälä, K.; Landis, M. J.; Mailund, T.; Nielsen, R.

10.1101/2022.09.06.506725 — genetics — Posted on 2022-09-06

3496 E. coli-{varphi}X174 genotype to phenotype map reveals flexibility and diversity in LPS structures

Romeyer Dherbey, J.; Parab, L.; Gallie, J.; Bertels, F.

10.1101/2022.09.06.506728 — evolutionary biology — Posted on 2022-09-06

3497 Profile likelihood-based parameter and predictive interval analysis guides model choice for ecological population dynamics

Simpson, M. J.; Walker, S.; Studerus, E. N.; Murphy, R. J.; McCue, S.; Maclaren, O.

10.1101/2022.09.05.506701 — ecology — Posted on 2022-09-06

3498 Meningeal IL-17 producing T cells mediate cognitive impairment in salt-sensitive hypertension

Santisteban, M. M.; Faraco, G.; Brea Lopez, D.; Wang, G.; Sobanko, M. J.; Sciortino, R.; Racchumi, G.; Waisman, A.; Anrather, J.; Iadecola, C.

10.1101/2022.09.05.506398 — neuroscience — Posted on 2022-09-06

3499 Sleep spindle maturation enhances slow oscillation-spindle coupling

Joechner, A.-K.; Hahn, M. A.; Gruber, G.; Hoedlmoser, K.; Werkle-Bergner, M.

10.1101/2022.09.05.506664 — neuroscience — Posted on 2022-09-06

3500 The amyloid precursor protein regulates synaptic transmission at medial perforant path synapses

Lenz, M.; Eichler, A.; Kruse, P.; Galanis, C.; Kleidonas, D.; Jedlicka, P.; Müller, U.; Deller, T.; Vlachos, A.

10.1101/2022.09.05.506635 — neuroscience — Posted on 2022-09-06

3501 Activity in the human superior colliculus associated with reaching for tactile targets

Prabhu, N. G.; Himmelbach, M.

10.1101/2022.09.06.506707 — neuroscience — Posted on 2022-09-06

3502 Neural cognitive signals during spontaneous movements in the macaque

Tremblay, S.; Testard, C.; DiTullio, R. W.; Inchauspe, J.; Petrides, M.

10.1101/2022.09.05.506681 — neuroscience — Posted on 2022-09-06

3503 White matter structural bases for predictive tapping synchronization

Garcia-Saldivar, P.; de Leon, C.; Concha, L.; Merchant, H.

10.1101/2022.09.05.506691 — neuroscience — Posted on 2022-09-06

3504 The history of multisensory discrepancies affects the ventriloquism effect and the immediate aftereffect differentially.

Kayser, C.; Park, H.; Heuer, H.

10.1101/2022.09.06.506717 — neuroscience — Posted on 2022-09-06

3505 MyD88-TLR4-dependent choroid plexus activation precedes perilesional inflammation and edema in intracerebral hemorrhage

Akeret, K.; Buzzi, R. M.; Thomson, B. R.; Schwendinger, N.; Klohs, J.; Schulthess, N.; Baselgia, L.; Hansen, K.; Regli, L.; Vallelian, F.; Hugelshofer, M.; Schaer, D.

10.1101/2022.09.06.506660 — neuroscience — Posted on 2022-09-06

3506 The PROSCOOP10 gene encodes two extracellular hydroxylated peptides and impacts flowering time in Arabidopsis

Guillou, M.-C.; Balliau, T.; Vergne, E.; Canut, H.; Chourre, J.; Herrera-Leon, C.; Ramos-Martin, F.; Ahmadi-Afzadi, M.; D'Amelio, N.; Ruelland, E.; Zivy, M.; Renou, J.-P.; Jamet, E.; Aubourg, S.

10.1101/2022.09.06.506713 — plant biology — Posted on 2022-09-06

3507 Acquisition of hybrid E/M phenotype associated with increased migration, drug resistance and stemness is mediated by reduced miR-18a levels in ER-negative breast cancer

Nair, M. G.; D, A.; M, C.; VP, S.; CE, A.; Rajarajan, S.; Sahoo, S.; Mohan, G.; Jayakumar, V. S.; Ramesh, R. S.; BS, S.; Jolly, M. K.; Maliekal, T. T.; Prabhu, J. S.

10.1101/2022.09.05.505398 — cancer biology — Posted on 2022-09-06

3508 ExoJ: an ImageJ2/Fiji plugin for automated spatiotemporal detection of exocytosis

Liu, J.; Verweij, F. J.; Van Niel, G.; Danglot, L.; Bun, P.

10.1101/2022.09.05.506585 — bioinformatics — Posted on 2022-09-06

3509 SE(3) Equivalent Graph Attention Network as an Energy-Based Model for Protein Side Chain Conformation

Liu, D.; Chen, S.; Zheng, S.; Zhang, S.; Yang, Y.

10.1101/2022.09.05.506704 — bioinformatics — Posted on 2022-09-06

3510 AHoJ: rapid, tailored search and retrieval of apo and holo protein structures for user-defined ligands

Feidakis, C. P.; Krivak, R.; Hoksza, D.; Novotny, M.

10.1101/2022.09.05.496878 — bioinformatics — Posted on 2022-09-06

3511 MAGE enables population level RNAseq driven genotyping and (differential) allelic divergence detection in healthy kidney and carcinoma

Stroobandt, C.; Goovaerts, T.; Coussement, L.; De Graeve, F.; Voorthuijzen, F.; Van Steenbergen, L.; Galle, J.; Van Criekinge, W.; De Meyer, T.

10.1101/2022.09.06.506720 — bioinformatics — Posted on 2022-09-06

3512 A Comprehensive Conceptual and Computational Dynamics Framework for Autonomous Regeneration of Form and Function in Biological Organisms

Samarasinghe, S.; Minh-Thai, T. N.

10.1101/2022.09.05.506675 — bioinformatics — Posted on 2022-09-06

3513 Decomposing spatial heterogeneity of cell trajectories with Paella

Hou, W.; Ji, Z.

10.1101/2022.09.05.506682 — bioinformatics — Posted on 2022-09-06

3514 A machine learning liver-on-a-chip system for safer drug formulation

Shi, Y.; Lin, C.-H.; Reker, D.; Steiger, C.; Hess, K.; Collins, J. E.; Tamang, S.; Ishida, K.; Lopes, A.; Wainer, J.; Hayward, A. M.; Walesky, C.; Goessling, W.; Traverso, G.

10.1101/2022.09.05.506668 — bioengineering — Posted on 2022-09-06

3515 From Gradient to Sectioning in CUBE: Workflow for Generating and Imaging Organoid with Localized Differentiation

Koh, I.; Hagiwara, M.

10.1101/2022.09.06.506732 — bioengineering — Posted on 2022-09-06

3516 Preliminary prospective study on the predictive significance of plasma miR-30b-5p through the study of echocardiographic modifications in Cavalier King Charles Spaniels affected by different stages of myxomatous mitral valve disease: the PRIME study

Ghilardi, S.; Lecchi, C.; Bagardi, M.; Romito, G.; Colombo, F. M.; Polli, M.; Franco, C.; Brambilla, P. G.

10.1101/2022.09.05.506710 — genomics — Posted on 2022-09-06

3517 intra-single cell sequencing (iSCseq) spotlights transcriptomic and epigenetic heterogeneity inside multinucleated osteoclast

Okada, H.; Terui, Y.; Omata, Y.; Seki, M.; Tani, S.; Miyahara, J.; Makabe, K.; Terashima, A.; Kanazawa, S.; Hosonuma, M.; Yano, F.; Kajiya, H.; Saito, T.; Suzuki, Y.; Okabe, K.; Baron, R.; Tanaka, S.; Chung, U.-i.; Hojo, H.

10.1101/2022.09.05.506360 — genomics — Posted on 2022-09-06

3518 Graph pangenome reveals functional, evolutionary, and phenotypic significance of human nonreference sequences

Wu, Z.; Li, T.; Jiang, Z.; Zheng, J.; Liu, Y.; Liu, Y.; Xie, Z.

10.1101/2022.09.05.506692 — genetics — Posted on 2022-09-06

3519 1 Natural Genetic Variation in a Dopamine Receptor is Associated With Variation in Female Fertility in Drosophila melanogaster

Lyman, R.; Lyman, R.; Yamamoto, A.; Huang, W.; Harbison, S.; Zhou, S.; Anholt, R.; Mackay, T. F. C.

10.1101/2022.09.06.506722 — evolutionary biology — Posted on 2022-09-06

3520 The relationship between spectral and plant diversity: disentangling the influence of metrics and habitat types

Perrone, M.; Di Febbraro, M.; Conti, L.; Divisek, J.; Chytry, M.; Keil, P.; Carranza, M. L.; Rocchini, D.; Torresani, M.; Moudry, V.; Simova, P.; Prajzlerova, D.; Müllerova, J.; Wild, J.

10.1101/2022.09.05.506583 — ecology — Posted on 2022-09-06

3521 Self-assembly of cellular neighborhoods converts stochastic signaling into sustained olfactory neurogenesis

Rajan, S. G.; Lombardo, J. N.; Nacke, L. M.; Manuchehrfar, F.; Wong, K.; Garcia, J.; Liang, J.; Saxena, A.

10.1101/2022.09.05.506659 — developmental biology — Posted on 2022-09-06

3522 Unravelling the impact of aging on the human endothelial lncRNA transcriptome

Drekolia, M.-K.; Talyan, S.; Cordellini Emidia, R.; Boon, R. A.; Guenther, S.; Looso, M.; Dumbovic, G.; Bibli, S.-I.

10.1101/2022.09.05.506634 — cell biology — Posted on 2022-09-06

3523 Deletion or inhibition of PTPRO mitigates diet-induced hepatic steatosis and inflammation in obesity

Shintani, T.; Suzuki, R.; Takeuchi, Y.; Shirasawa, T.; Noda, M.

10.1101/2022.09.05.506586 — immunology — Posted on 2022-09-06

3524 Spreading depolarization causes reperfusion failure after cerebral ischemia

Torteli, A.; Toth, R.; Berger, S. D.; Samardzic, S.; Bari, F.; Menyhart, A.; Farkas, E.

10.1101/2022.09.05.506665 — neuroscience — Posted on 2022-09-06

3525 Multi-Echo Investigations of Positive and Negative CBF and Concomitant BOLD Changes

Devi, R.; Lepsien, J.; Lorenz, K.; Schlumm, T.; Mildner, T.; Möller, H. E.

10.1101/2022.09.05.506629 — neuroscience — Posted on 2022-09-06

3526 NUDT6, the Antisense Protein of FGF2 Gene, Plays a Depressogenic Role by Promoting Inflammation and Suppressing Neurogenesis without Altering FGF2 Signaling

Uzay, B.; Hokelekli, F. O.; Yilmaz, M.; Esen, E. C.; Basar, K.; Bahadir-Varol, A.; Ayhan, Y.; Dalkara, T.; Eren-Kocak, E.

10.1101/2022.09.05.506638 — neuroscience — Posted on 2022-09-06

3527 High-Resolution Magnetization-Transfer Imaging of Post-Mortem Marmoset Brain: Comparisons with Relaxometry and Histology

Marschner, H.; Pampel, A.; Müller, R.; Reimann, K.; Bock, N.; Morawski, M.; Geyer, S.; Möller, H. E.

10.1101/2022.09.05.506600 — neuroscience — Posted on 2022-09-06

3528 Self-generated brain-wide spiking cascades govern replay dynamics in the hippocampus

Yang, Y.; Leopold, D.; Duyn, J.; Liu, X.

10.1101/2022.09.05.506667 — neuroscience — Posted on 2022-09-06

3529 Estrogen signaling in the dorsal raphe regulates binge-like drinking in mice

Torres Irizarry, V. C.; Feng, B.; Yang, X.; Patel, N.; Schaul, S.; Ibrahimi, L.; Ye, H.; Luo, P.; Carrillo Saenz, L.; Lai, P.; Kota, M.; Dixit, D.; Wang, C.; Lasek, A. W.; He, Y.; Xu, P.

10.1101/2022.09.05.506646 — neuroscience — Posted on 2022-09-06

3530 RNA-deficient TDP-43 causes loss of free nuclear TDP-43 by sequestration

Keating, S.; Bademosi, A.; San Gil, R.; Walker, A. K.

10.1101/2022.09.06.506721 — neuroscience — Posted on 2022-09-06

3531 A continuous vibration-based virtual tactile motion across fingertips

Adibi, M.

10.1101/2022.09.06.506303 — neuroscience — Posted on 2022-09-06

3532 Accurate flux predictions using tissue-specific gene expression in plant metabolic modeling

Kaste, J. A. M.; Shachar-Hill, Y.

10.1101/2022.09.05.506655 — systems biology — Posted on 2022-09-06

3533 The selective force driving metabolic operon assembly

Fondi, M.; Pini, F.; Riccardi, C.; Gemo, P.; Brilli, M.

10.1101/2022.09.05.506644 — systems biology — Posted on 2022-09-06

3534 Identifying Lymph Node Metastasis-related Factors in Breast Cancer using Differential Modular and Mutational Structural Analysis

liu, X.; Yang, B.; Huang, X.; Yan, W.; Hu, G.

10.1101/2022.09.06.506724 — systems biology — Posted on 2022-09-06

3535 Base Editing for Reprogramming Cyanobacterium Synechococcus elongatus

Wang, S.-Y.; Li, X.; Wang, S.-G.; Xia, P.-F.

10.1101/2022.09.05.506134 — synthetic biology — Posted on 2022-09-06

3536 Statistical learning of large-scale genetic data: How to run a genome-wide association study of gene-expression data using the 1000 GenomesProject data

Sugolov, A.; Emmenegger, E.; Sun, L.; Paterson, A. D.

10.1101/2022.09.03.506492 — scientific communication and education — Posted on 2022-09-06

3537 Transgressive and parental dominant gene expression and cytosine methylation during seed development in Brassica napus hybrids

Orantes-Bonilla, M.; Wang, H.; Lee, H.; Golicz, A. A.; Hu, D.; Li, W.; Zou, J.; Snowdon, R. J.

10.1101/2022.09.05.506610 — plant biology — Posted on 2022-09-06

3538 High-throughput field phenotyping reveals that selection in breeding has affected the phenology and temperature response of wheat in the stem elongation phase

Roth, L.; Kronenberg, L.; Aasen, H.; Walter, A.; Hartung, J.; van Eeuwijk, F. A.; Piepho, H.-P.; Hund, A.

10.1101/2022.09.05.506627 — physiology — Posted on 2022-09-06

3539 Photoelectrochemical imaging of action potentials for single cardiomyocytes through contact force manipulation of organoids

Jacques, R.; Zhou, B.; Marhuenda, E.; Gorecki, J.; Das, A.; Iskratsch, T.; Krause, S.

10.1101/2022.09.05.506608 — biophysics — Posted on 2022-09-06

3540 A model-free Data-Driven paradigm for in situ patient-specific prediction of human brain response to ultrasound stimulation

Salahshoor, H.; Ortiz, M.

10.1101/2022.09.01.506248 — biophysics — Posted on 2022-09-06

3541 EzMechanism: An Automated Tool to Propose Catalytic Mechanisms of Enzyme Reactions

Ribeiro, A. J. M.; Riziotis, I. G.; Tyzack, J. D.; Borkakoti, N.; Thornton, J. M.

10.1101/2022.09.05.506575 — bioinformatics — Posted on 2022-09-06

3542 In silico identification of miRNAs related to mitochondrial dysfunction in amyotrophic lateral sclerosis

Baykal, G.; Erkal, B.; Vural Korkut, S.

10.1101/2022.09.05.506596 — bioinformatics — Posted on 2022-09-06

3543 A Multithreaded Model for Cancer Tissue Heterogeneity: An Application

Choudhury, S.

10.1101/2022.09.05.505544 — bioinformatics — Posted on 2022-09-06

3544 In silico evaluation of the role of the long non-coding RNA LINC00092 in thyroid cancer progression ; regulation of the miR-34a-5p/RCAN1 axis

Morovat, S.; Morovat, P.; Kamali, M. J.; Teimourian, S.

10.1101/2022.09.04.506551 — bioinformatics — Posted on 2022-09-06

3545 Attention-based GCN Integrates Multi-omics Data for Breast Cancer Subtype Classification and Patient-specific Gene Marker Identification

Li, Y.

10.1101/2022.09.05.506572 — bioinformatics — Posted on 2022-09-06

3546 ChimeraTE: A pipeline to detect chimeric transcripts derived from genes and transposable elements

Siqueira Oliveira, D.; Fablet, M.; Larue, A.; Vallier, A.; Aparecida Carareto, C.; Rebollo, R.; Vieira, C.

10.1101/2022.09.05.505575 — bioinformatics — Posted on 2022-09-06

3547 TransporterPAL: An integrative database Transporter Prediction ALgorithm

Dyekjaer, J. D.; Andersen, A. K. B.; Madsen, J. A. V.; Morth, J. P.; Jensen, L. J.; Borodina, I.

10.1101/2022.09.05.506577 — bioinformatics — Posted on 2022-09-06

3548 Bridging The Evolving Semantics: A Data Driven Approach to Knowledge Discovery In Biomedicine

Jha, K.

10.1101/2022.09.05.506661 — bioinformatics — Posted on 2022-09-06

3549 In vitro-in silico correlation of three-dimensional turbulent flows in an idealized mouth-throat model

Nof, E.; Bhardwaj, S.; Koullapis, P.; Bessler, R.; Kassinos, S.; Sznitman, J.

10.1101/2022.09.05.506589 — bioengineering — Posted on 2022-09-06

3550 BBB-on-a-chip with Integrated micro-TEER for permeability evaluation of multi-functionalized gold nanorods against Alzheimer's disease

Palma Florez, S. F.; Lopez-Canosa, A.; Morales-Zavala, F.; Castano, O.; Kogan, M. J.; Samitier, J.; Lagunas, A.; Mir, M.

10.1101/2022.09.05.505851 — bioengineering — Posted on 2022-09-06

3551 The Norwegian Mother, Father, and Child cohort study (MoBa) genotyping data resource: MoBaPsychGen pipeline v.1

Corfield, E. C.; Frei, O.; Shadrin, A. A.; Rahman, Z.; Lin, A.; Athanasiu, L.; Cevdet Akdeniz, B.; Hannigan, L.; Wootton, R. E.; Austerberry, C.; Hughes, A.; Tesli, M.; Westlye, L. T.; Stefansson, H.; Stefansson, K.; Njolstad, P. R.; Magnus, P.; Davies, N. M.; Appadurai, V.; Hemani, G.; Hovig, E.; Zayats, T.; Ask, H.; Reichborn-Kjennerud, T.; Andreassen, O. A.; Havdahl, A.

10.1101/2022.06.23.496289 — genetics — Posted on 2022-09-06

3552 Rad51-mediated interhomolog recombination during budding yeast meiosis is promoted by the meiotic recombination checkpoint and the conserved Pif1 helicase

Ziesel, A.; Weng, Q.; Ahuja, J. S.; Bhattacharya, A.; Dutta, R.; Cheng, E.; Börner, G. V.; Lichten, M.; Hollingsworth, N. M.

10.1101/2022.09.05.506590 — genetics — Posted on 2022-09-06

3553 The influence of genetic structure on phenotypic diversity in the Australian mango (Mangifera indica) gene pool

Wilkinson, M. J.; Yamashita, R.; James, M. E.; Bally, I. S. E.; Dillon, N. L.; Ali, A.; Hardner, C. M.; Ortiz-Barrientos, D.

10.1101/2022.09.04.506567 — evolutionary biology — Posted on 2022-09-06

3554 Convergent selection on juvenile hormone signaling is associated with the evolution of eusociality in bees

Jones, B. M.; Rubin, B. E.; Dudchenko, O.; Kingwell, C. J.; Traniello, I. M.; Wang, Z. Y.; Kapheim, K. M.; Wyman, E. S.; Adastra, P. A.; Liu, W.; Parsons, L. R.; Jackson, S. R.; Goodwin, K.; Davidson, S. M.; McBride, M. J.; Webb, A. E.; Omufwoko, K. S.; Van Dorp, N.; Fernandez Otarola, M.; Pham, M.; Omer, A. D.; Weisz, D.; Schraiber, J.; Villanea, F.; Wcislo, W. T.; Paxton, R. J.; Hunt, B. G.; Aiden, E. L.; Kocher, S. D.

10.1101/2021.04.14.439731 — evolutionary biology — Posted on 2022-09-06

3555 Individual variation in the avian gut microbiota: the influence of host state and environmental heterogeneity

Somers, S. E.; Davidson, G. L.; Johnson, C. N.; Reichert, M. S.; Crane, J. M. S.; Ross, R. P.; Stanton, C.; Quinn, J. L.

10.1101/2022.09.05.506623 — ecology — Posted on 2022-09-06

3556 How far to build it before they come? Analyzing the use of the Field of Dreams hypothesis in bull kelp restoration

Arroyo-Esquivel, J.; Baskett, M. L.; McPherson, M.; Hastings, A.

10.1101/2021.10.27.466118 — ecology — Posted on 2022-09-06

3557 Plants stand still but hide: imperfect and heterogeneous detection is the rule when counting plants

Perret, J.; Besnard, A.; Charpentier, A.; Papuga, G.

10.1101/2022.09.05.506614 — ecology — Posted on 2022-09-06

3558 A note on discretising Keyfitz entropy

de Vries, C.; Bernard, C.; Salguero-Gomez, R.

10.1101/2022.09.05.506601 — ecology — Posted on 2022-09-06

3559 Exposure to global change and microplastics elicits an immune response in an endangered coral

Bove, C. B.; Greene, K.; Sugierski, S.; Kriefall, N. G.; Huzar, A. K.; Hughes, A. M.; Sharp, K.; Fogarty, N. D.; Davies, S. W.

10.1101/2022.09.05.506609 — ecology — Posted on 2022-09-06

3560 Design principles for selective polarization of PAR proteins by cortical flows

Illukkumbura, R.; Hirani, N.; Borrego-Pinto, J.; Bland, T.; Ng, K.; Hubatsch, L.; McQuade, J.; Endres, R.; Goehring, N.

10.1101/2022.09.05.506621 — cell biology — Posted on 2022-09-06

3561 Identification of Biomarker Genes Based on Multi-Omics Analysis in Non-Small Cell Lung Cancer

Xia, J.; He, H.-b.; Liu, Y.; Wang, Y.; Shu, K.-X.; Ma, M.-Y.

10.1101/2022.09.05.506624 — molecular biology — Posted on 2022-09-06

3562 Divergence in bacterial ecology is reflected by difference in population genetic structure, phage-predator load and host range

Cahier, K.; Piel, D.; Barcia Cruz, R.; Gounenege, D.; Wegner, M.; Monot, M.; Romalde, J.; Le Roux, F.

10.1101/2022.09.06.506642 — microbiology — Posted on 2022-09-06

3563 Molecular fate-mapping of serum antibodies reveals the effects of antigenic imprinting on repeated immunization

Schiepers, A.; van 't Wout, M. F.; Greaney, A. J.; Zang, T.; Muramatsu, H.; Lin, P. J.; Tam, Y. K.; Mesin, L.; Starr, T. N.; Bieniasz, P. D.; Pardi, N.; Bloom, J. D.; Victora, G. D.

10.1101/2022.08.29.505743 — immunology — Posted on 2022-09-06

3564 Reduction of the HIV-1 reservoir in T cells from persons with HIV-1 on suppressive antiretroviral therapy using expanded natural killer cells ex vivo

Checkley Luttge, M. A.; LUTTGE, B. G.; Dobrowolski, C.; Wald, D. N.; McMahon, D.; Haidar, G.; Sobolewski, M. D.; Enick, P. N.; Cyktor, J.; Mellors, J. W.; Karn, J.

10.1101/2022.09.05.506592 — immunology — Posted on 2022-09-06

3565 Microglia mediate synaptic plasticity induced by 10 Hz repetitive transcranial magnetic stimulation

Eichler, A.; Kleidonas, D.; Turi, Z.; Fliegauf, M.; Kirsch, M.; Pfeifer, D.; Masuda, T.; Prinz, M.; Lenz, M.; Vlachos, A.

10.1101/2021.10.03.462905 — neuroscience — Posted on 2022-09-06

3566 Striatal ups or downs? Neural correlates of monetary reward anticipation, cue reactivity and their interaction in alcohol use disorder and gambling disorder

van Timmeren, T.; van Holst, R. J.; Goudriaan, A. E.

10.1101/2022.09.05.506605 — neuroscience — Posted on 2022-09-06

3567 The Tripod neuron: a minimal structural reduction of the dendritic tree

Quaresima, A.; Duarte, R.; Fitz, H.; van den Broek, D.; Hagoort, P.; Petersson, K. M.

10.1101/2022.09.05.506197 — neuroscience — Posted on 2022-09-06

3568 Metamodelling of a two-population spiking neural network

Skaar, J.-E. W.; Stasik, A. J.; Plesser, H. E.; Einevoll, G. T.; Tondel, K.

10.1101/2022.09.05.506616 — neuroscience — Posted on 2022-09-06

3569 Rapid fluctuations in functional connectivity of cortical networks encode spontaneous behavior

Benisty, H.; Moberly, A. H.; Lohani, S.; Barson, D.; Coifman, R. R.; Mishne, G.; Cardin, J. A.; Higley, M. J.

10.1101/2021.08.15.456390 — neuroscience — Posted on 2022-09-06

3570 Muscle FOXO-specific overexpression and endurance exercise protects skeletal muscle and heart from defects caused by a high-fat diet in young Drosophila

Wen, D. t.; Chen, Y.-l.; Hou, W.-q.

10.1101/2022.09.05.506594 — physiology — Posted on 2022-09-06

3571 Exploration of million-sequence phylogenies with Taxonium

Sanderson, T.

10.1101/2022.06.03.494608 — bioinformatics — Posted on 2022-09-06

3572 Warmer temperatures result in maladaptive learning of sexual preferences

Holveck, M.-J.; Muller, D.; Visser, B.; Timmermans, A.; Colonval, L.; Jan, F.; Crucifix, M.; Nieberding, C.

10.1101/2020.11.05.369561 — evolutionary biology — Posted on 2022-09-06

3573 Cryo-ET of infected cells reveals that a succession of two lattices drives vaccinia virus assembly

Hernandez-Gonzalez, M.; Calcraft, T.; Nans, A.; Rosenthal, P. B.; Way, M.

10.1101/2022.08.11.503617 — microbiology — Posted on 2022-09-06

3574 SARS-CoV-2 invades cognitive centers of the brain and induces Alzheimer's-like neuropathology

Shen, W.-B.; Elahi, M.; Logue, J.; Yang, P.; Baracco, L.; Reece, E. A.; Wang, B.; Li, L.; Blanchard, T.; Han, Z.; Frieman, M.; Rissman, R. A.; Yang, P.

10.1101/2022.01.31.478476 — neuroscience — Posted on 2022-09-06

3575 Learning inverse folding from millions of predicted structures

Hsu, C.; Verkuil, R.; Liu, J.; Lin, Z.; Hie, B.; Sercu, T.; Lerer, A.; Rives, A.

10.1101/2022.04.10.487779 — systems biology — Posted on 2022-09-06

3576 Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir

Hu, Y.; Lewandowski, E. M.; Tan, H.; Morgan, R. T.; Zhang, X.; Jacobs, L. M.; Butler, S. G.; Mongora, M. V.; Choy, J. S.; Chen, Y.; Wang, J.

10.1101/2022.06.28.497978 — pharmacology and toxicology — Posted on 2022-09-06

3577 Introgression between highly divergent sea squirt genomes: an adaptive breakthrough?

Fraisse, C.; Le Moan, A.; Roux, C.; Dubois, G.; Daguin-Thiebaut, C.; Gagnaire, P.-A.; Viard, F.; Bierne, N.

10.1101/2022.03.22.485319 — evolutionary biology — Posted on 2022-09-06

3578 Coherence of Terrestrial Vertebrate Species Richness with External Drivers Across Scales and Taxonomic Groups

O'Malley, C. P. B.; Roberts, G. G.; Mannion, P. D.; Hackel, J.; Wang, Y.

10.1101/2022.01.21.477239 — ecology — Posted on 2022-09-06

3579 Vertical gradients in photosynthetic physiology diverge at the latitudinal range extremes of white spruce

Schmiege, S. C.; Griffin, K. L.; Boelman, N. T.; Vierling, L. A.; Bruner, S. G.; Min, E.; Maguire, A. J.; Jensen, J.; Eitel, J. U. H.

10.1101/2022.05.06.490824 — ecology — Posted on 2022-09-06

3580 BCM3D 2.0: Accurate segmentation of single bacterial cells in dense biofilms using computationally generated intermediate image representations

Zhang, J.; Wang, Y.; Donarski, E.; Toma, T. T.; Miles, M. T.; Acton, S.; Gahlmann, A.

10.1101/2021.11.26.470109 — microbiology — Posted on 2022-09-06

3581 Representations of complex contexts: A role for hippocampus

Dimsdale-Zucker, H. R.; Montchal, M. E.; Reagh, Z. M.; Wang, S.-F.; Libby, L. A.; Ranganath, C. R.

10.1101/766311 — neuroscience — Posted on 2022-09-06

3582 From proteins to nanoparticles: domain-agnostic predictions of nanoscale interactions.

Saldinger, J.; Raymond, M.; Elvati, P.; Violi, A.

10.1101/2022.08.09.503361 — bioinformatics — Posted on 2022-09-06

3583 Spatial heterogeneity alters the trade-off betweengrowth and dispersal during a range expansion

Zamberletti, P.; Roques, L.; Lavigne, F.; Papaïx, J.

10.1101/2022.04.07.487471 — evolutionary biology — Posted on 2022-09-06

3584 Efficacy and safety of glycosphingolipid SSEA-4 targeting CAR-T cells in solid tumors

10.1101/2022.09.02.506335 — cancer biology — Posted on 2022-09-06

3585 Compartments in medulloblastoma with extensive nodularity are connected through differentiation along the granular precursor lineage

Ghasemi, D. R.; Okonechnikov, K.; Rademacher, A.; Tirier, S.; Maass, K. K.; Schumacher, H.; Sundheimer, J.; Statz, B.; Rifaioglu, A. S.; Bauer, K.; Schumacher, S.; Bortolomeazzi, M.; Giangaspero, F.; Ernst, K. J.; Saez-Rodriguez, J.; Jones, D. T. W.; Kawauchi, D.; Mallm, J.-P.; Rippe, K.; Korshunov, A.; Pfister, S. M.; Pajtler, K. W.

10.1101/2022.09.02.506321 — cancer biology — Posted on 2022-09-06

3586 Continental-scale hyperspectral tree species classification in the United States National Ecological Observatory Network

Marconi, S.; Weinstein, B. G.; Zou, S.; Bohlman, S. A.; Zare, A.; Singh, A.; Stewart, D.; Harmon, I.; Steinkraus, A.; White, E. P.

10.1101/2021.12.22.473714 — ecology — Posted on 2022-09-06

3587 Structural studies reveal that endosomal cations promote formation of infectious CVA9 A particles, facilitating RNA and VP4 release.

Domanska, A.; Plavec, Z.; Ruokolainen, V.; Löflund, B.; Marjomäki, V.; Butcher, S. J.

10.1101/2022.09.02.506448 — microbiology — Posted on 2022-09-06

3588 Integrated human-machine interface for closed-loop stimulation using implanted and wearable devices

Sladky, V.; Kremen, V.; McQuown, K.; Mivalt, F.; Brinkmann, B.; van Gompel, J.; Miller, K. J.; Denison, T.; Worrell, G. A.

10.1101/2022.09.04.506494 — neuroscience — Posted on 2022-09-06

3589 Metaplasticity: Dark exposure boosts excitability and visual plasticity in adult human cortex

Min, S. H.; Wang, Z.; Chen, M.; Hu, R.; Gong, L.; He, Z.; Wang, X.; Hess, R. F.; Zhou, J.

10.1101/2022.09.04.506561 — neuroscience — Posted on 2022-09-06

3590 Erotic cue exposure increases physiological arousal, biases choices towards immediate rewards and attenuates model-based reinforcement learning

Mathar, D.; Wiebe, A.; Tuzsus, D.; Peters, J.

10.1101/2022.09.04.506507 — neuroscience — Posted on 2022-09-06

3591 Graded optogenetic activation of the auditory pathway for neural network analysis and hearing restoration

Mittring, A.; Moser, T.; Huet, A. T.

10.1101/2022.09.05.506618 — neuroscience — Posted on 2022-09-06

3592 4.1N and SAP97 regulate different phases of AMPA receptor intracellular transport

Bonnet, C.; Charpentier, J.; Retailleau, N.; Choquet, D.; Coussen, F.

10.1101/2022.09.05.506328 — neuroscience — Posted on 2022-09-06

3593 Mapping of Glutamate Metabolism using 1H FID-MRSI after oral Administration of Glc at 9.4 T

Ziegs, T.; Ruhm, L.; Wright, A. M.; Henning, A.

10.1101/2022.09.05.506579 — neuroscience — Posted on 2022-09-06

3594 Cardiovascular Hemodynamics in Mice with Tumor Necrosis Factor Receptor - Associated Factor 2 Mediated Cytoprotection in the Heart

10.1101/2022.09.03.506447 — biophysics — Posted on 2022-09-06

3595 Spring dynamics and regional variation in two different root developmental types in seedlings of a boreal evergreen conifer species

Sugai, T.; Ishizuka, W.; Masumoto, T.; Endo, I.; Ide, J.; Fujita, S.; Kobayashi, M.; Makita, N.

10.1101/2022.09.03.506439 — ecology — Posted on 2022-09-06

3596 Sea lamprey nests promote the diversity of benthic macroinvertebrate assemblages

Dhamelincourt, M.; Rives, J.; Pons, M.; Larranaga, A.; Tentelier, C.; Elosegi, A.

10.1101/2022.09.04.506553 — ecology — Posted on 2022-09-06

3597 Senescence-induced cellular reprogramming drives cnidarian whole-body regeneration

Salinas-saavedra, M.; Febrimarsa, F.; Krasovec, G.; Horkan, H. R.; Baxevanis, A. D.; Frank, U.

10.1101/2022.09.02.506310 — developmental biology — Posted on 2022-09-06

3598 Evaluating the Influence of Anatomical Accuracy and Electrode Positions on EEG Forward Solutions

Nielsen, J. D.; Puonti, O.; Xue, R.; Thielscher, A.; Madsen, H. H.

10.1101/2022.09.01.505675 — neuroscience — Posted on 2022-09-06

3599 WiNGS: Widely integrated NGS platform for federated genome analysis

Chizari, H.; Sattanathan, N.; Ardeshirdavani, A.; Shabani, N.; Huremagic, B.; Vermeesch, J. R.; Moreau, Y.; Vandeweyer, G.

10.1101/2022.06.23.497325 — bioinformatics — Posted on 2022-09-06

3600 Hunter-gatherer admixture facilitated natural selection in Neolithic European farmers

Davy, T.; Ju, D.; Mathieson, I.; Skoglund, P.

10.1101/2022.09.05.506481 — evolutionary biology — Posted on 2022-09-06

3601 Glucose oxidation and nutrients availability drive neural crest development

Nekooie-Marnany, N.; Fodil, R.; Fereol, S.; Depp, M.; Motterlini, R.; Foresti, R.; Duband, J.-L.; Dufour, S.

10.1101/2022.09.05.506657 — developmental biology — Posted on 2022-09-06

3602 The impact of genetic risk for Alzheimers disease on the structural brain networks of young adults

Mirza-Davies, A.; Foley, S.; Caseras, X.; Baker, E.; Holmans, P.; Escott-Price, V.; Jones, D. K.; Harrison, J. R.; Messaritaki, E.

10.1101/2021.09.22.461338 — neuroscience — Posted on 2022-09-06

3603 Scream's roughness confers a privileged access to the brain during sleep

Legendre, G. Y. T.; Moyne, M.; Dominguez-Borras, J.; Kumar, S.; Sterpenich, V.; Schwartz, S.; Arnal, L.

10.1101/2022.09.05.506631 — neuroscience — Posted on 2022-09-06

3604 GBZ File Format for Pangenome Graphs

Siren, J.; Paten, B.

10.1101/2022.07.12.499787 — bioinformatics — Posted on 2022-09-06

3605 Molecular docking: Bioactive compounds of Mimosa pudica as an inhibitor of Candida albicans Sap 3

Gholam, G. M.; Firdausy, I. A.; Artika, I. M.; Abdillah, R. M.; Firmansyah, R. P.

10.1101/2022.09.06.506736 — biochemistry — Posted on 2022-09-06

3606 Divergence in bacterial ecology is reflected by difference in population genetic structure, phage-predator load and host range

Cahier, K.; Piel, D.; Barcia Cruz, R.; Gounenege, D.; Wegner, M.; Monot, M.; Romalde, J.; Le Roux, F.

10.1101/2022.09.06.506642 — microbiology — Posted on 2022-09-06

3607 Attenuation hotspots in neurotropic human astroviruses

Ali, H.; Lulla, A.; Nicholson, A. S.; Wignall-Fleming, E. B.; OConnor, R. L.; Vu, D.-L.; Graham, S. C.; Deane, J. E.; Guix, S.; Lulla, V.

10.1101/2022.09.06.506719 — microbiology — Posted on 2022-09-06

3608 Ergonomic risk factors and Work-related Musculoskeletal Disorders among Fireworks workers in West Bengal, India: A cross-sectional study

Hossain, Z. M.; Ganguly, S.; Laskar, P.

10.1101/2021.06.07.447237 — physiology — Posted on 2022-09-06

3609 New Structure of Class II Fructose-1,6-Bisphosphatase from Francisella tularensis suggest a novel catalytic mechanism for the entire class

Abad-Zapatero, C.; Selezneva, A. I.; Harding, L. N. M.; Gutka, H.; Movahedzadeh, F.

10.1101/2022.09.05.506711 — biochemistry — Posted on 2022-09-06

3610 Assessment of the residential Finnish wolf population combines DNA captures, citizen observations and mortality data using a Bayesian state-space model

Mäntyniemi, S.; Helle, I.; Kojola, I.

10.1101/2021.12.21.473527 — ecology — Posted on 2022-09-06

3611 Computational modelling of cambium activity provides a regulatory framework for simulating radial plant growth

Lebovka, I.; Hay Mele, B.; Liu, X.; Zakieva, A.; Schlamp, T.; Gursanscky, N.; Merks, R. M. H.; Grosseholz, R.; Greb, T.

10.1101/2020.01.16.908715 — plant biology — Posted on 2022-09-06

3612 PD-L1ATTAC mice reveal the potential of targeting PD-L1 expressing cells in cancer therapy

Fueyo-Marcos, E.; Fustero-Torre, C.; Lopez, G.; Anton, M. E.; Al-Shahrour, F.; Fernandez-Capetillo, O.; Murga, M.

10.1101/2022.07.22.501095 — cancer biology — Posted on 2022-09-06

3613 Combating pancreatic cancer with ovarian cancer cells

lin, x.; Cui, C.; Cui, Q.

10.1101/2022.09.01.506158 — cancer biology — Posted on 2022-09-06

3614 Detection and Role of Feline Apolipoprotein B mRNA-editing Enzyme Catalytic Polypeptide Subunit 3G-Like Protein in Feline Cells and Tissues

Assogba, B. D.; Chaudhary, S.; Kaur, H.; Soo, R.; Dela Cruz, M. A. P.; Assogba, J. M. G.

10.1101/2022.09.03.504613 — cell biology — Posted on 2022-09-06

3615 Analytical time-dependent distributions for gene expression models with complex promoter switching mechanisms

Jia, C.; Li, Y.

10.1101/2022.01.05.475050 — systems biology — Posted on 2022-09-06

3616 Analytical time-dependent distributions for gene expression models with complex promoter switching mechanisms

Jia, C.; Li, Y.

10.1101/2022.01.05.475050 — systems biology — Posted on 2022-09-06

3617 Metamorphosis imposes variable constraints on genome expansion

Mueller, R. L.; Cressler, C. E.; Schwarz, R. S.; Chong, R. A.; Butler, M. A.

10.1101/2021.05.05.442795 — evolutionary biology — Posted on 2022-09-06

3618 Copy number variations shape the structural diversity of Arabidopsis metabolic gene clusters and are associated with the climatic gradient

Marszalek-Zenczak, M.; Satyr, A.; Wojciechowski, P.; Zenczak, M.; Sobieszczanska, P.; Brzezinski, K.; Iefimenko, T.; Figlerowicz, M.; Zmienko, A.

10.1101/2022.09.05.506152 — genomics — Posted on 2022-09-05

3619 Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

Arora, R.; Cao, C.; Kumar, M.; Sinha, S.; Chanda, A.; McNeil, R.; Samuel, D.; Arora, R. K.; Matthew, T. W.; Chandarana, S.; Hart, R.; Dort, J. C.; Biernaskie, J.; Neri, P.; Hyrcza, M. D.; Bose, P.

10.1101/2022.09.04.505581 — cancer biology — Posted on 2022-09-05

3620 Oocyte and cumulus cell cooperativity and metabolic plasticity under the direction of oocyte paracrine factors

Richani, D.; Poljak, A.; Wang, B.; Mahbub, S. B.; Biazik, J.; Campbell, J. M.; Habibalahi, A.; Stocker, W. A.; Marinova, M. B.; Nixon, B.; Bustamante, S.; Skerrett-Byrne, D. A.; Harrison, C. A.; Goldys, E.; Gilchrist, R. B.

10.1101/2022.09.05.506599 — developmental biology — Posted on 2022-09-05

3621 IL-33 Involved in the Progression of Liver Fibrosis Through Innate Immunity Cells (MΦ) Regulated by ICOS/ICOSL Signaling in Early Stage of Mice Schistosomiasis

Liu, L.; Wang, P.; Xie, S.-Q.; Pu, W.-J.; Xu, J.; Xia, c.

10.1101/2022.09.05.506595 — immunology — Posted on 2022-09-05

3622 STING activation promotes autologous type I interferon-dependent development of type 1 regulatory T cells during malaria

Wang, Y.; Rivera, F.; Edwards, C.; Frame, T.; Engel, J. A.; Bukali, L.; Na, J.; Ng, S.; Corvino, D.; Montes de Oca, M.; Bunn, P.; Soon, M.; Andrew, D.; Loughland, J.; Amante, F.; Barber, B.; McCarthy, J. S.; Lopez, J. A.; Boyle, M. J.; Engwerda, C.

10.1101/2022.09.04.506109 — immunology — Posted on 2022-09-05

3623 Scavenger receptor B1 facilitates the endocytosis of Escherichia coli via TLR4 signaling in mammary gland infection

Taban, Q.; Ahmad, S. M.; Mumtaz, P. T.; Bhat, B.; Haq, E.; Magray, S.; Saleeem, S.; Shabir, N.; Muhee, A.; Kashoo, Z. A.; Hameed, M.; Malik, A.; Ganai, N. A.; Shah, R. A.

10.1101/2022.09.05.506597 — immunology — Posted on 2022-09-05

3624 Membrane Targeted Azobenzene Drives Optical Modulation of Bacterial Membrane Potential

de Souza-Guerreiro, T. C.; Bondelli, G.; Grobas, I.; Donini, S.; Sesti, V.; Bertarelli, C.; Lanzani, G.; Asally, M.; Paterno, G. M.

10.1101/2022.09.05.506195 — biophysics — Posted on 2022-09-05

3625 An Alpha-helical Lid Guides the Target DNA toward Catalysis in CRISPR-Cas12a

Saha, A.; Ahsan, M.; Arantes, P. R.; Schmitz, M.; Chanez, C.; Jinek, M.; Palermo, G.

10.1101/2022.09.05.506663 — biophysics — Posted on 2022-09-05

3626 Mechanical regulation of Titin N2B-us conformation and its binding to FHL2

SUN, Y.; HUANG, W.; LE, S.; Yan, J.

10.1101/2022.09.05.506602 — biophysics — Posted on 2022-09-05

3627 Chorography and conformational dynamism of the Soluble Human Fibrinogen in solution

Sen, M.; Hudson, N. E.; Offenbacher, A. R.; Iavarone, A. T.; Nguyen, Q.; Ray, K.; Popovic, G.; Manandhar, P.; Pinelo, J. E. E.

10.1101/2022.09.05.506423 — biochemistry — Posted on 2022-09-05

3628 Reducing the Complexity of Fc Glycan Enables the Construction of Antibody Conjugates with Unexpected High Efficiency and Payload Capacity via Glycoengineering

Yang, Y.; Song, Z. t.; Tian, T.; Zhao, Z.; Chen, J.; Hu, J. p.; Jiang, X.; Yang, G. l.; Xue, Q.; Zhao, X. l.; Sha, W. x.; Yang, Y.; Li, J. P.

10.1101/2022.09.04.506510 — biochemistry — Posted on 2022-09-05

3629 The cytidine deaminase APOBEC3G drives cancer mutagenesis and clonal evolution in bladder cancer

Liu, W.; Newhall, K. P.; Khani, F.; Barlow, L.; Nguyen, D.; Gu, L.; Eng, K.; Bhinder, B.; Uppal, M.; Recapet, C.; Sboner, A.; Ross, S. R.; Elemento, O.; Chelico, L.; Faltas, B. M.

10.1101/2022.09.05.503899 — genomics — Posted on 2022-09-05

3630 Efficient repair of human homozygous genetic mutation by CRISPR/Cas9 mediated interlocus gene conversion

Yang, F.; Pang, J.; Liu, G.; Yang, Y.; Qin, S.; Zhang, Y.; Lai, Y.; Liang, D.; Wu, Y.

10.1101/2022.09.05.506576 — genetics — Posted on 2022-09-05

3631 Universal DNA methylation age across mammalian tissues

Lu, A. T.; Fei, Z.; Haghani, A.; Robeck, T. R.; Zoller, J. A.; Li, C. Z.; Lowe, R.; Yan, Q.; Zhang, J.; Vu, H.; Ableava, J.; Acosta-Rodriguez, V. A.; Adams, D. M.; Almunia, J.; Aloysius, A.; Ardehali, R.; Arneson, A.; Baker, C. S.; Banks, G.; Belov, K.; Bennett, N. C.; Black, P.; Blumstein, D. T.; Bors, E. K.; Breeze, C. E.; Brooke, R. T.; Brown, J. L.; Carter, G.; Caulton, A.; Cavin, J. M.; Chakrabarti, L.; Chatzistamou, I.; Chen, H.; Cheng, K.; Chiavellini, P.; Choi, O.-W.; Clarke, S.; Cooper, L. N.; Cossette, M.-L.; Day, J.; DeYoung, J.; DiRocco, S.; Dold, C.; Ehmke, E. E.; Emmons, C. K.; E

10.1101/2021.01.18.426733 — developmental biology — Posted on 2022-09-05

3632 Ultra-sensitive coupling between organ growth and size by YAP-1 ensures uniform body plan proportions in C. elegans

Stojanovski, K.; Gheorghe, I.; Lanjuin, A.; Mair, W. B.; Towbin, B. D.

10.1101/2022.09.05.506666 — developmental biology — Posted on 2022-09-05

3633 The effect of short-term activation of AHL15 on long-term plant developmental change and transcriptome profile

Karami, O.; Henkel, C.; Offringa, R.

10.1101/2022.09.05.506087 — developmental biology — Posted on 2022-09-05

3634 A novel role for cystathionine gamma lyase in the control of p53: impact on endothelial senescence and metabolic reprograming

Hu, J.; Leisegang, M. S.; Looso, M.; Dumbovic, G.; Wittig, J.; Drekolia, M.-K.; Guenther, S.; John, D.; Siragusa, M.; Zukunft, S.; Oo, J.; Wittig, I.; Hille, S.; Weigert, A.; Knapp, S.; Brandes, R. P.; Mueller, O. J.; Papapetropoulos, A.; Sigala, F.; Dobreva, G.; Fleming, I.; Bibli, S. I.

10.1101/2022.09.05.506654 — cell biology — Posted on 2022-09-05

3635 Streamlined, cell-specific single-molecule RNA-FISH of core clock mRNAs in clock neurons in whole mount Drosophila brains

Yuan, Y.; Padilla, M. A.; Clark, D.; Yadlapalli, S.

10.1101/2022.09.05.506677 — cell biology — Posted on 2022-09-05

3636 The mitochondrial Cu+ transporter PiC2 (SLC25A3) is a target of MTF1 and contributes to the development of skeletal muscle in vitro

McCann, C.; Quinteros, M.; Adelugba, I.; Morgada, M. N.; Castelblanco, A. R.; Davis, E.; Lanzirotti, A.; Hainer, S. J.; Vila, A. J.; Navea, J. G.; PADILLA-BENAVIDES, T.

10.1101/2022.09.05.506690 — cell biology — Posted on 2022-09-05

3637 A translational repression reporter assay for the analysis of RNA-binding protein consensus sites

Nowacki, J.; Malenica, M.; Schmeing, S.; Schiller, D.; Buchmuller, B.; 't Hart, P.

10.1101/2022.09.05.506580 — molecular biology — Posted on 2022-09-05

3638 STORM-seq Reveals Differentiation Trajectories of Primary Human Fallopian Tube Epithelium

Johnson, B. K.; Rhodes, M.; Wegener, M.; Himadewi, P.; Foy, K.; Schipper, J. L.; Siwicki, R. A.; Rossell, L. L.; Siegwald, E. J.; Chesla, D. W.; Sheridan, R. T. C.; Adams, M.; Triche, T. J.; Shen, H.

10.1101/2022.03.14.484332 — molecular biology — Posted on 2022-09-05

3639 The injury-induced circular RNA circGLIS3 activates dermal fibroblasts to promote wound healing

Toma, M.-A.; Wang, Q.; Li, D.; Xiao, Y.; Niu, G.; Geara, J.; Vij, M.; Piipponen, M.; Liu, Z.; Zhang, L.; Bian, X.; Wang, A.; Sommar, P.; Xu Landen, N.

10.1101/2022.09.05.506337 — molecular biology — Posted on 2022-09-05

3640 Nucleotide level linkage of transcriptional elongation and polyadenylation

Geisberg, J. V.; Moqtaderi, Z.; Fong, N.; Erickson, B.; Bentley, D.; Struhl, K.

10.1101/2022.09.05.506603 — molecular biology — Posted on 2022-09-05

3641 Rgs1 is a regulator of effector gene expression during plant infection by the rice blast fungus Magnaporthe oryzae

Tang, B.; Yan, X.; Ryder, L. S.; Cruz-Mireles, N.; Soanes, D. M.; Molinari, C.; Foster, A. J.; Talbot, N. J.

10.1101/2022.09.04.506535 — molecular biology — Posted on 2022-09-05

3642 Autophagy alterations in white and brown adipose tissues of mice exercised under different training protocols

Tamargo-Gomez, I.; Fernandez-Sanjurjo, M.; Codina-Martinez, H.; Tomas-Zapico, C.; Iglesias-Gutierrez, E.; Fernandez, A. F.; Fernandez-Garcia, B.

10.1101/2022.09.05.505110 — molecular biology — Posted on 2022-09-05

3643 Dual control of lysogeny and phage defense by a phosphorylation-based toxin/antitoxin system

Guo, Y.; Tang, K.; Sit, B.; Gu, J.; Chen, R.; Lin, J.; Lin, S.; Liu, X.; Wang, W.; Gao, X.; Nie, Z.; Liu, T.; Waldor, M. K.; Wang, X.

10.1101/2022.09.05.506569 — microbiology — Posted on 2022-09-05

3644 A unique case in which Kimoto-style fermentation was completed with Leuconostoc as the dominant genus without transitioning to Lactobacillus.

Ito, K.; Niwa, R.; Yamagishi, Y.; Kobayashi, K.; Tsuchida, Y.; Hoshino, G.; Nakagawa, T.; Watanabe, T.

10.1101/2022.09.05.505584 — microbiology — Posted on 2022-09-05

3645 Reconstitution of a minimal ESX-5 type VII secretion systems uncovers the essential role of the PPE proteins in secretion

Bunduc, C. M.; Kuijl, C.; Ummels, R.; Marlovits, T. C.; Bitter, W.; Houben, E. N. G.

10.1101/2022.09.05.506643 — microbiology — Posted on 2022-09-05

3646 Substrate availability and not thermal-acclimation controls microbial temperature sensitivity response to long term warming

Domeignoz-Horta, L. A.; Pold, G.; Erb, H.; Sebag, D.; Verrecchia, E.; Northen, T.; Louie, K.; Eloe-Fadrosh, E.; Pennacchio, C.; Knorr, M. A.; Frey, S. D.; Melillo, J. M.; DeAngelis, K. M.

10.1101/2022.09.05.506639 — microbiology — Posted on 2022-09-05

3647 Longitudinal characterization of circulating extracellular vesicles and small RNA during simian immunodeficiency virus infection and antiretroviral therapy

Huang, Y.; Liao, Z.; Dang, P.; Queen, S.; Abreu, C. M.; Zheng, L.; Witwer, K. W.

10.1101/2022.09.04.506571 — microbiology — Posted on 2022-09-05

3648 Tryptophol acetate and tyrosol acetate, metabolites secreted by a probiotic yeast, block cytokine storm

malka, o.; malishev, r.; bersudsky, m.; rajendran, m.; krishnamohan, m.; shaik, j.; chamovitz, d.; tikhonov, e.; sultan, e.; koren, o.; apte, r.; rosental, b.; voronov, e.; jelinek, r.

10.1101/2021.12.16.472991 — immunology — Posted on 2022-09-05

3649 Structural basis for membrane attack complex inhibition by CD59

Couves, E. C.; Gardner, S.; Voisin, T. B.; Bickel, J. K.; Stansfeld, P. J.; Tate, E. W.; Bubeck, D.

10.1101/2022.09.05.506672 — immunology — Posted on 2022-09-05

3650 Co-fluctuations of neural activity define intra-V1 networks related to perceptual organization

Valdes-Sosa, M. J.; Ontivero-Ortega, M.; Iglesias-Fuster, J.; Lage-Castellanos, A.; Galan-Garcia, L.; Valdes-Sosa, P. A.

10.1101/2022.08.22.504869 — neuroscience — Posted on 2022-09-05

3651 Mesenchymal-epithelial transition in lymph node metastases of oral squamous cell carcinoma is accompanied by ZEB1 expression

Horny, K.; Sproll, C.; Peiffer, L.; Furtmann, F.; Gerhardt, P.; Gravemeyer, J.; Stoecklein, N. H.; Spassova, I.; Becker, J. C.

10.1101/2022.02.03.478962 — cancer biology — Posted on 2022-09-05

3652 Drug specificity and affinity are encoded in the probability of cryptic pocket opening in myosin motor domains

Meller, A.; Lotthammer, J. M.; Smith, L. G.; Novak, B.; Lee, L. A.; Kuhn, C. C.; Greenberg, L.; Leinwand, L. A.; Greenberg, M. J.; Bowman, G. R.

10.1101/2022.09.05.506254 — biophysics — Posted on 2022-09-05

3653 Uptake of aminoglycosides through outer membrane porins in Escherichia coli

Paul, E.; Ghai, I.; Hoeroempoeli, D.; Broetz-Oesterhelt, H.; Winterhalter, M.; Bafna, J. A.

10.1101/2022.09.05.506620 — biophysics — Posted on 2022-09-05

3654 Satelight: Self-Attention-Based Model for Epileptic Spike Detection from Multi-Electrode EEG

Fukumori, K.; Yoshida, N.; Sugano, H.; Nakajima, M.; Tanaka, T.

10.1101/2021.06.17.448793 — bioengineering — Posted on 2022-09-05

3655 mtHsp70 converts mitochondrial proteostasis distress into impaired protein import

Banerjee, R.; Trauschke, V.; Bertram, N.; Aretz, I.; Osman, C.; Lamb, D. C.; Mokranjac, D.

10.1101/2022.09.05.506649 — biochemistry — Posted on 2022-09-05

3656 Molecular insights into peptide agonist engagement with the PTH1 receptor

Cary, B. P.; Gerrard, E. J.; Belousoff, M. J.; Fletcher, M. M.; Jiang, Y.; Russell, I. C.; Piper, S. J.; Wootten, D.; Sexton, P. M.

10.1101/2022.09.04.506565 — biochemistry — Posted on 2022-09-05

3657 Transcriptome profiling of histone acetylation and methylation writers and erasers gene families during mouse spermatogenesis

Gonzalez, C. R.; Barbero, G.; de Sousa Serro, M.; Perez Lujan, C.; Vitullo, A. D.; Gonzalez, B.

10.1101/2022.05.29.493915 — developmental biology — Posted on 2022-09-05

3658 A Scribble/Cdep/Rac pathway regulates follower cell crawling and cluster cohesion during collective border cell migration

Campanale, J. P.; Mondo, J. A.; Montell, D. J.

10.1101/2022.01.04.474957 — cell biology — Posted on 2022-09-05

3659 Augmin prevents merotelic attachments by promoting proper arrangement of bridging and kinetochore fibers

Stimac, V.; Koprivec, I.; Manenica, M.; Simunic, J.; Tolic, I. M.

10.1101/2020.09.10.291740 — cell biology — Posted on 2022-09-05

3660 Predicting vertical ground reaction forces from 3D accelerometry using reservoir computers leads to accurate gait event detection

Bach, M. M.; Dominici, N.; Daffertshofer, A.

10.1101/2022.02.14.480318 — neuroscience — Posted on 2022-09-05

3661 Anxiety-like behaviors in mice unmasked: Revealing sex differences in anxiety using a novel light-heat conflict test

Lee, S. E.; Greenough, E. K.; Oancea, P.; Fonken, L. K.; Gaudet, A. D.

10.1101/2022.09.02.506410 — neuroscience — Posted on 2022-09-05

3662 Resting EEG power spectra across middle to late life: Associations with age, cognition, APOE-ε4 carriage and cardiometabolic burden

Smith, A. E.; Chau, A.; Greaves, D.; Keage, H.; Feuerriegel, D. C.

10.1101/2022.09.01.506258 — neuroscience — Posted on 2022-09-05

3663 SOGO-SOFI, light-modulated super-resolution optical fluctuation imaging using only 20 raw frames for high-fidelity reconstruction

Xu, P.; Xue, F.; He, W.; Peng, D.; You, H.; Zhang, M.

10.1101/2022.09.03.506455 — biophysics — Posted on 2022-09-05

3664 The Cilialyzer - a freely available open-source software for a standardised identification of impaired mucociliary activity facilitating the diagnostic testing for PCD

Schneiter, M.; Tschanz, S. A.; Mueller, L.; Frenz, M.

10.1101/2022.09.04.506514 — biophysics — Posted on 2022-09-05

3665 Molecular Simulations and NMR Reveal How Lipid Fluctuations Affect Membrane Mechanics

Doktorova, M.; Khelashvili, G.; Ashkar, R.; Brown, M. F.

10.1101/2022.09.03.506496 — biophysics — Posted on 2022-09-05

3666 bootRanges: Flexible generation of null sets of genomic ranges for hypothesis testing

Mu, W.; Davis, E. S.; Lee, S.; Dozmorov, M.; Phanstiel, D. H.; Love, M. I.

10.1101/2022.09.02.506382 — bioinformatics — Posted on 2022-09-05

3667 Relationship between swimming velocity and trunk twist motion in short-distance crawl swimming

Hyodo, H.; Koga, D.; Sengoku, Y.; Wada, T.

10.1101/2022.09.04.506549 — bioengineering — Posted on 2022-09-05

3668 Prefrontal representation of affective stimuli: importance of stress, sex, and context

Wallace, T.; Myers, B.

10.1101/2022.09.02.506435 — neuroscience — Posted on 2022-09-05

3669 Pyfiber: an open source python library that facilitates the merge of operant behavior and fiber photometry- focus on intravenous self-administration

Conlisk, D. E.; Ceau, M.; Fiancette, J.-F.; Winke, N.; Darmagnac, E.; Herry, C.; Deroche-Gamonet, V.

10.1101/2022.09.02.506312 — neuroscience — Posted on 2022-09-05

3670 Reactivation-induced memory integration prevents proactive interference in perceptual learning

Huang, Z.; Niu, Z.; Li, S.

10.1101/2022.09.01.506161 — neuroscience — Posted on 2022-09-05

3671 Disentangled multi-subject and social behavioral representations through a constrained subspace variational autoencoder (CS-VAE)

Yi, D.; Musall, S.; Churchland, A.; Padilla-Coreano, N.; Saxena, S.

10.1101/2022.09.01.506091 — neuroscience — Posted on 2022-09-05

3672 An automated BIDS-App for brain segmentation of human fetal functional MRI data

Nichols, E. S.; Correa, S.; Van Dyken, P.; Kai, J.; Kuehn, T. K.; de Ribaupierre, S.; Duerden, E. G.; Khan, A. R.

10.1101/2022.09.02.506391 — neuroscience — Posted on 2022-09-05

3673 Longitudinal assessment of water-reaching reveals altered cortical activity and fine motor coordination defects in a Huntington Disease model

Wang, Y.; Sepers, M. D.; Xiao, D.; Raymond, L. A.; Murphy, T. H.

10.1101/2022.09.02.505959 — neuroscience — Posted on 2022-09-05

3674 Canonical and Replicable Multi-Scale Intrinsic Connectivity Networks in 100k+ Resting-State fMRI Datasets

Iraji, A.; Fu, Z.; Faghiri, A.; Duda, M.; Chen, J.; Rachakonda, S.; DeRamus, T. P.; Kochunov, P.; Adhikari, B. M.; Belger, A.; Ford, J.; Mathalon, D. H.; Pearlson, G. D.; Potkin, S. G.; Preda, A.; Turner, J. A.; Van Erp, T. G. M.; Bustillo, J. R.; Yang, K.; Ishizuka, K.; Sawa, A.; Hutchison, K.; Osuch, E. A.; Theberge, J.; Abbott, C.; Mueller, B. A.; Zhi, D.; Zhuo, C.; Liu, S.; Xu, Y.; Salman, M.; Liu, J.; Du, Y.; SUI, J.; Adali, T.; Calhoun, V.

10.1101/2022.09.03.506487 — neuroscience — Posted on 2022-09-05

3675 Microsaccades transiently lateralise EEG alpha activity

Liu, B.; Nobre, A. C.; van Ede, F.

10.1101/2022.09.02.506318 — neuroscience — Posted on 2022-09-05

3676 Structure-based prediction of Ras-effector binding affinities and design of 'branchegetic' interface mutations

Junk, P.; Kiel, C.

10.1101/2022.09.04.506480 — systems biology — Posted on 2022-09-05

3677 The UIP honeycomb airway cells are the site of mucin biogenesis with deranged cilia

Herrera, J. A.; Dingle, L. A.; Montero, M. A.; Rajamiyer, V.; Blaikley, J.; Granato, F.; Pearson, S.; Lawless, C.; Thornton, D. J.

10.1101/2022.09.03.506451 — pathology — Posted on 2022-09-05

3678 Tumor removal limits prostate cancer cell dissemination in bone cortex and osteoblasts induce cancer cell dormancy

Liu, R.; Su, S.; Liu, K.; Xing, J.; Stangis, M.; Jacho, D. P.; Yildirim-Ayan, E. D.; Yu, H.; Chen, B.; Li, X.

10.1101/2022.09.02.506436 — cancer biology — Posted on 2022-09-05

3679 Establishment and characterization of a tumoroid biobank derived from dog patients' mammary tumors for translational research

Raffo-Romero, A.; Aboulouard, S.; Bouchaert, E.; Rybicka, A.; Tierny, D.; Hajjaji, N.; Fournier, I.; Salzet, M.; Duhamel, M.

10.1101/2022.09.04.506533 — cancer biology — Posted on 2022-09-05

3680 Gene Expression Profiles Reveal Potential Targets for Breast Cancer Diagnosis and Treatment

Nasirpour, M. H.; Sabery Anvar, M.; Nasirpour, A.; Salimi, M.; Sepahyr, S.; Minuchehr, Z.

10.1101/2022.09.03.504469 — cancer biology — Posted on 2022-09-05

3681 Cryogenic X-ray crystallographic studies of biomacromolecules at Turkish Light Source: Turkish DeLight

Atalay, N.; Akcan, E. K.; Gul, M.; Ayan, E.; Destan, E.; Ertem, F. B.; Tokay, N.; Cakilkaya, B.; Nergiz, Z.; Karakadioglu, G.; Kepceoglu, A.; Yapici, I.; Tosun, B.; Baldir, N.; Yildirim, G.; Johnson, J. A.; Guven, O.; Shafiei, A.; Arslan, N. E.; Yilmaz, M.; Kulakman, C.; Paydos, S. S.; Cinal, Z. S.; Sabanoglu, K.; Pazarceviren, A.; Yilmaz, A.; Canbay, B.; Asci, B.; Kartal, E.; Tavli, S.; Caliseki, M.; Goc, G.; Mermer, A.; Yesilay, G.; Altuntas, S.; Tateishi, H.; Otsuka, M.; Fujita, M.; Tekin, S.; Ciftci, H.; Durdagi, S.; Dinler Doganay, G.; Karaca, E.; Kaplan Turkoz, B.; Kabasakal, B. V.; Kati

10.1101/2022.09.03.506456 — biophysics — Posted on 2022-09-05

3682 Ingres: from single-cell RNA-seq data to single-cell probabilistic Boolean networks

Victori, P.; Buffa, F. M.

10.1101/2022.09.04.506528 — bioinformatics — Posted on 2022-09-05

3683 Differential kinetic analysis using nucleotide recoding RNA-seq and bakR

Vock, I. W.; Simon, M.

10.1101/2022.09.02.505697 — bioinformatics — Posted on 2022-09-05

3684 Characterization of magnetic nanoparticles from the shells of freshwater mussel L fortunei and marine P perna mussels

Valadao Cardoso, A.; Carvalho e Souza, C.; Dantas, M. S.; Machado, C. S.; Fraga Freitas, E. T.; Krohling, A. C.; do Rosario, V. A. M.; Dias Heinene, L. G.

10.1101/2022.09.04.506556 — bioengineering — Posted on 2022-09-05

3685 Female Friendships: Social Network Analysis as a tool to understand intra-group affiliation in semi-commensal lion-tailed macaques (Macaca silenus)

Dhawale, A. K.; Sinha, A.

10.1101/2022.09.01.506153 — animal behavior and cognition — Posted on 2022-09-05

3686 Fractionated brain irradiation profoundly reduces hippocampal immature neuron numbers without affecting spontaneous behavior and cognition in mice

Kuil, L.; Seigers, R.; Loos, M.; de Gooijer, M. C.; Compter, A.; Boogerd, W.; van Tellingen, O.; Smit, A. B.; Schagen, S. B.

10.1101/2022.09.01.506166 — animal behavior and cognition — Posted on 2022-09-05

3687 Savanna chimpanzees (Pan troglodytes verus) in Senegal react to deadly snakes and other reptiles: Testing the snake detection hypothesis

Pruetz, J.; LaDuke, T. C.; Dobson, K.

10.1101/2022.09.04.506548 — animal behavior and cognition — Posted on 2022-09-05

3688 Localizing post-admixture adaptive variants with object detection on ancestry-painted chromosomes

Hamid, I.; Korunes, K. L.; Schrider, D.; Goldberg, A.

10.1101/2022.09.04.506532 — genomics — Posted on 2022-09-05

3689 Jack of all trades: genome assembly of Wild Jack and comparative genomics of Artocarpus

Patil, A. B.; Vajja, S. S.; Raghavendra, S.; Satish, B. N.; Kushalappa, C. G.; Vijay, N.

10.1101/2022.09.02.506353 — genomics — Posted on 2022-09-05

3690 Expanded utility of the R package qgg with applications within genomic medicine

Rohde, P. D.; Sorensen, I. F.; Sorensen, P.

10.1101/2022.09.03.506466 — genetics — Posted on 2022-09-05

3691 Gene interaction perturbation network deciphers a high-resolution taxonomy in colorectal cancer

Liu, Z.; Weng, S.; Dang, Q.; Xu, H.; Ren, Y.; Guo, C.; Xing, Z.; Sun, Z.; Han, X.

10.1101/2022.09.02.506442 — genetics — Posted on 2022-09-05

3692 Rising above the noise: The influence of populationdynamics on the evolution of acoustic signaling

Suswaram, M.; Bhat, U.; Yeakel, J. D.

10.1101/2022.09.02.506422 — evolutionary biology — Posted on 2022-09-05

3693 Twenty-seven ZAD-ZNF genes of Drosophila melanogaster are orthologous to the embryo polarity determining mosquito gene cucoid

Li, M.; Kasan, K.; Saha, Z.; Yoon, Y.; Schmidt-Ott, U.

10.1101/2022.09.04.506554 — evolutionary biology — Posted on 2022-09-05

3694 Risk factors and spatiotemporal analysis of classical swine fever in Ecuador

Acosta, A.; Dietze, K.; Baquero, O. S.; Vizzotto Osowski, G.; Imbacuan, C.; Burbano, A.; Ferreira, F.; Depner, K.

10.1101/2022.09.02.506027 — ecology — Posted on 2022-09-05

3695 Predicting predator-prey interactions in terrestrial endotherms using random forest

Llewelyn, J. S.; Strona, G.; Dickman, C. R.; Greenville, A.; Wardle, G.; Lee, M. S. Y.; Doherty, S.; Shabani, F.; Saltre, F.; Bradshaw, C. J. A.

10.1101/2022.09.02.506446 — ecology — Posted on 2022-09-05

3696 Rgs1 is a regulator of effector gene expression during plant infection by the rice blast fungus Magnaporthe oryzae

Talbot, N. J.; Tang, B.; Yan, X.; Ryder, L. S.; Cruz-Mireles, N.; Soanes, D. M.; Molinari, C.; Foster, A. J.

10.1101/2022.09.04.506535 — molecular biology — Posted on 2022-09-05

3697 Formulating a TMEM176B blocker in nanoparticles uncouples its paradoxical roles in innate and adaptive antitumoral immunity.

Victoria, S.; Castro, A.; Pittini, A.; Olivera, D.; Russo, S.; Cebrian, I.; Mombru, A. W.; Osinaga, E.; Pardo, H.; Segovia, M.; Hill, M.

10.1101/2022.09.02.506404 — immunology — Posted on 2022-09-05

3698 Real-Time Interactive Visualization and Analysis of Neurotransmitter Data

Thomas Homescu, A.; Murray, T.

10.1101/2022.09.03.506483 — neuroscience — Posted on 2022-09-05

3699 Genetic tools that target mechanoreceptors produce reliable labeling of bladder afferents

Tran, E. L.; Stuedemann, S. A.; Link, O. D.; Crawford, L. K.

10.1101/2022.09.03.506472 — neuroscience — Posted on 2022-09-05

3700 Multichannel neural spike sorting with spike reduction and positional feature

Mohammadi, Z.; Denman, D.; Klug, A.; Lei, T. C.

10.1101/2022.09.02.506385 — neuroscience — Posted on 2022-09-05

3701 Ultrafast (>400 Hz) network oscillations induced in thalamorecipient cortical layers by optogenetic activation of thalamocortical axons

Hu, H.; Hostetler, R. E.; Agmon, A.

10.1101/2022.09.02.506344 — neuroscience — Posted on 2022-09-05

3702 Random Tactile Noise Stimulation Reveals Beta-Rhythmic Impulse Response Function of the Somatosensory System

Chota, S.; VanRullen, R.; Gulbinaite, R.

10.1101/2022.09.03.506453 — neuroscience — Posted on 2022-09-05

3703 Effect of Application of Titanium Dioxide in the Management of Fusarium Wilt and Fruit Yield of Some Tomato Accessions

Rilwan, O. O.; Popoola, A. R.; Sikiru, G. A.

10.1101/2022.09.02.506275 — pathology — Posted on 2022-09-05

3704 Spatial transcriptomics reveals distinct and conserved tumor core and edge architectures that predict survival and targeted therapy response

Arora, R.; Cao, C.; Kumar, M.; Sinha, S.; Chanda, A.; McNeil, R.; Samuel, D.; Arora, R. K.; Matthew, T. W.; Chandarana, S.; Hart, R.; Dort, J. C.; Biernaskie, J.; Neri, P.; Hyrcza, M. D.; Bose, P.

10.1101/2022.09.04.505581 — cancer biology — Posted on 2022-09-05

3705 Utility of stromal lymphocytes in diagnosis and predicting upgrade of B3 breast lesions from core biopsies

Kader, T.; Hendry, S.; Provenzano, E.; Jayawardana, M. W.; Pang, J.-M.; Elder, K.; Byrne, D. J.; Tjoeka, L.; Frazer, H. M.; House, E.; Jayasinghe, S.; Keane, H.; Murugasu, A.; Rajan, N.; Miligy, I. M.; Green, A. R.; Rakha, E. A.; Fox, S.; Mann, G. B.; Campbell, I. G.; Gorringe, K. L.

10.1101/2022.09.02.506444 — cancer biology — Posted on 2022-09-05

3706 Nearest neighbor search on embeddings rapidly identifies distant protein relations

Schütze, K.; Heinzinger, M.; Steinegger, M.; Rost, B.

10.1101/2022.09.04.506527 — bioinformatics — Posted on 2022-09-05

3707 Quantifying and Visualizing Uncertainty for Source Localization in Electrocardiographic Imaging

Njeru, D. K.; Athawale, T. M.; France, J. J.; Johnson, C. R.

10.1101/2022.09.02.506414 — bioengineering — Posted on 2022-09-05

3708 Modular Streaming Pipeline of Eye/Head Tracking Data Using Tobii Pro Glasses 3

Rahimi Nasrabadi, H.; Alonso, J.-M.

10.1101/2022.09.02.506255 — animal behavior and cognition — Posted on 2022-09-05

3709 Tyramine and its AmTYR1 receptor modulate attention in honey bees (Apis mellifera)

Latshaw, J. S.; Mazade, R. E.; Petersen, M.; Mustard, J. A.; Sinakevitch, I.; Wissler, L.; Guo, X.; Cook, C. N.; Lei, H.; Gadau, J.; Smith, B. H.

10.1101/2022.09.02.506392 — animal behavior and cognition — Posted on 2022-09-05

3710 Optimization and deoptimization of codons in SARS-CoV-2 and the implications for vaccine development

Wu, X.; Shan, K.; Zan, F.; Tang, X.; Qian, Z.; Lu, J.

10.1101/2022.09.03.506470 — evolutionary biology — Posted on 2022-09-05

3711 Trade-offs constrain adaptive pathways to T6 survival

MacGillivray, K. A.; Ng, S. L.; Wiesenfeld, S.; Guest, R. L.; Jubery, T.; Silhavy, T. J.; Ratcliff, W. C.; Hammer, B. K.

10.1101/2022.09.02.506412 — evolutionary biology — Posted on 2022-09-05

3712 Genesis of Ecto-symbiotic features based on Commensalistic Syntrophy

Krishnan, N.; Csiszar, V.; Mori, T.; Garay, J.

10.1101/2022.09.04.506536 — evolutionary biology — Posted on 2022-09-05

3713 Comparing Inference under the MSC versus the MSC-with-Recombination

Yan, Z.; Ogilvie, H. A.; Nakhleh, L.

10.1101/2022.09.03.506495 — evolutionary biology — Posted on 2022-09-05

3714 Evidence of prezygotic isolation, but not assortative mating, between locally adapted populations of Fundulus heteroclitus across a salinity gradient

Brennan, R.; Whitehead, A.

10.1101/2022.09.03.506458 — evolutionary biology — Posted on 2022-09-05

3715 Ecology and age, but not genetic ancestry, predict fetal loss in a wild baboon hybrid zone

Fogel, A. S.; Oduor, P. O.; Nyongesa, A. W.; Kimwele, C. N.; Alberts, S. C.; Archie, E. A.; Tung, J.

10.1101/2022.09.03.505836 — evolutionary biology — Posted on 2022-09-05

3716 Tracking canopy gap dynamics across four sites in the Brazilian Amazon

Gorgens, E. B.; Keller, M.; Jackwon, T. D.; Marra, D. M.; Reis, C. R.; Almeida, D. R. A.; Coomes, D.; Ometto, J. P.

10.1101/2022.09.03.506473 — ecology — Posted on 2022-09-05

3717 Spatial variation in red deer density in relation to forest disturbance and ungulate management in a transboundary forest ecosystem

Tourani, M.; Franke, F.; Heurich, M.; Henrich, M.; Peterka, T.; Ebert, C.; Oeser, J.; Edelhoff, H.; Milleret, C.; Dupont, P.; Bischof, R.; Peters, W.

10.1101/2022.09.04.506509 — ecology — Posted on 2022-09-05

3718 Combined Molnupiravir and Nirmatrelvir Treatment Improves the Inhibitory Effect on SARS-CoV-2 in Rhesus Macaques

Rosenke, K.; Lewis, M.; Feldmann, F.; Bohrnsen, E.; Schwarz, B.; Okumura, A.; Bohler, W. F.; Callison, J.; Shaia, C.; Bosio, C.; Lovaglio, J.; Saturday, G.; Jarvis, M.; Feldmann, H.

10.1101/2022.09.03.506479 — microbiology — Posted on 2022-09-05

3719 Delayed SARS-CoV-2 Spread and Olfactory Cell Lineage Impairment in Close-Contact Infection Syrian Hamster Models

Ueha, R.; Ito, T.; Ueha, S.; Furukawa, R.; Kitabatake, M.; Ouji-Sageshima, N.; Uranaka, T.; Tanaka, H.; Nishijima, H.; Kondo, K.; Yamasoba, T.

10.1101/2022.09.03.506499 — microbiology — Posted on 2022-09-05

3720 ApoE4 causes severe COVID-19 outcomes via downregulation of ACE2

Chen, F.; Chen, Y.; Ke, Q.; Wang, Y.; Chen, X.; Peng, X.; Cai, Y.; Li, S.; Sun, Y.; Ji, Y.; Jiang, Y.; Wu, W.; Wang, Y.; Cui, L.

10.1101/2022.09.04.506474 — neuroscience — Posted on 2022-09-05

3721 A matter of availability: Neural representations of task-relevant stimulus features are sharper when stimuli are memorized rather than perceived.

Chota, S.; Gayet, S.; Kenemans, J. L.; Olivers, C. N. L.; Van der Stigchel, S.

10.1101/2022.09.01.506184 — neuroscience — Posted on 2022-09-05

3722 Predictive neural representations of naturalistic dynamic input

de Vries, I. E. J.; Wurm, M. F.

10.1101/2022.09.02.506366 — neuroscience — Posted on 2022-09-05

3723 High-fidelity 3D live-cell nanoscopy through data-driven enhanced super-resolution radial fluctuation

Laine, R. F.; Heil, H. S.; Coelho, S.; Nixon-Abell, J.; Jimenez, A.; Galgani, T.; Stubb, A.; Follain, G.; Goyette, J.; Webster, S.; Culley, S.; Jacquemet, G.; Hajj, B.; Leterrier, C.; Henriques, R.

10.1101/2022.04.07.487490 — biophysics — Posted on 2022-09-05

3724 Differentiation signals from glia are fine-tuned to set neuronal numbers during development

Prasad, A. R.; Lago-Baldaia, I.; Bostock, M. P.; Housseini, Z.; Fernandes, V. M.

10.1101/2021.12.13.472383 — neuroscience — Posted on 2022-09-05

3725 Optimal burstiness in populations of spiking neurons facilitates decoding of decreases in tonic firing

Durian, S.; Agrios, M.; Schwartz, G. W.

10.1101/2022.04.21.488999 — neuroscience — Posted on 2022-09-05

3726 Light activation of Orange Carotenoid Protein reveals bicycle-pedal single-bond isomerization

Chukhutsina, V.; Baxter, J.; Fadini, A.; Morgan, R. M.; Pope, M.; Maghlaoui, K.; Orr, C.; Wagner, A.; van Thor, J.

10.1101/2022.01.17.475858 — biophysics — Posted on 2022-09-05

3727 Resistance bioassays and allele characterisation inform analysis of Spodoptera frugiperda (Lepidoptera: Noctuidae) introduction pathways in Asia and Australia

Tay, W. T.; Rane, R. V.; James, W.; Gordon, K. H. J.; Downes, S.; Kim, J.; Kuniata, L.; Walsh, T. K.

10.1101/2022.02.08.479273 — evolutionary biology — Posted on 2022-09-05

3728 Masculinization of the X-chromosome in aphid soma and gonads

Jaquiery, J.; Simon, J.-C.; Robin, S.; Richard, G.; Peccoud, J.; Boulain, H.; Legeai, F.; Tanguy, S.; Prunier-Leterme, N.; Letrionnaire, G.

10.1101/2021.08.13.453080 — evolutionary biology — Posted on 2022-09-05

3729 Lipid droplets modulate proteostasis, SQST-1/SQSTM1 dynamics, and lifespan in C. elegans

Kumar, A. V.; Mills, J.; Parker, W. M.; Leitao, J.; Rodriguez, D. I.; Ng, C.; Patel, R.; Aguilera, J. L.; Johnson, J. R.; Wong, S. Q.; Lapierre, L. R.

10.1101/2021.04.22.440991 — cell biology — Posted on 2022-09-05

3730 IL-22BP production is heterogeneously distributed in Crohn's disease

Fantou, A.; Lagrue, E.; Laurent, T.; Delbos, L.; Blandin, S.; Jarry, A.; Beriou, G.; Braudeau, C.; Salabert-Le Guen, N.; Marin, E.; Moreau, A.; Podevin, J.; Bourreille, A.; Josien, R.; Martin, J. C.

10.1101/2021.04.07.438837 — immunology — Posted on 2022-09-05

3731 The evo-MOTiF pipeline and database for studying protein motif evolution in a structural context

de Boissier, P.; Zweig, N.; Habermann, B. H.

10.1101/2022.08.29.505684 — bioinformatics — Posted on 2022-09-05

3732 MTORC2 is a physiological hydrophobic motif kinase of S6 Kinase 1.

Majeed, S. T.; Majeed, R.; Malik, A.; Zargar, M. A.; Andrabi, K. I.

10.1101/2021.08.17.456612 — molecular biology — Posted on 2022-09-05

3733 Alone in a crowd: Effect of a nonfunctional lateral line on expression of the social hormone parathyroid hormone 2.

Venuto, A.; Smith, C. P.; Cameron-Pack, M.; Erickson, T.

10.1101/2022.05.06.490781 — neuroscience — Posted on 2022-09-05

3734 Joint inference of adaptive and demographic history from temporal population genomic data

Pavinato, V. A. C.; De Mita, S.; Marin, J.-M.; de Navascues, M.

10.1101/2021.03.12.435133 — evolutionary biology — Posted on 2022-09-05

3735 A common cis-regulatory variant impacts normal-range and disease-associated human facial shape through regulation of PKDCC during chondrogenesis

Mohammed, J.; Arora, N.; Matthews, H.; Hansen, K.; Bader, M.; Shaffer, J. R.; Weinberg, S. M.; Swigut, T.; Peter Claes, P.; Selleri, L.; Wysocka, J.

10.1101/2022.09.05.506587 — developmental biology — Posted on 2022-09-05

3736 Automatic Sample Segmentation & Detection of Parkinson's Disease Using Synthetic Staining & Deep Learning

Pearce, B. M.; Coetzee, P. L.; Rowland, D.; Linfoot, S.; Dexter, D. T.; Gveric, D. O.; Gentleman, S.

10.1101/2022.08.30.505459 — pathology — Posted on 2022-09-05

3737 Combining molecular dynamics simulations and scoring method to computationally model ubiquitylated linker histones in chromatosomes

Sawade, K.; Peter, C.; Marx, A.; Kukharenko, O.

10.1101/2022.09.01.506295 — bioinformatics — Posted on 2022-09-05

3738 Projection in genomic analysis: A theoretical basis to rationalize tensor decomposition and principal component analysis as feature selection tools

Taguchi, Y.-h.; Turki, T.

10.1101/2020.10.02.324616 — bioinformatics — Posted on 2022-09-05

3739 Expression and Splicing Mediate Distinct Biological Signals

Helweg Dam, S.; Olsen, L. R.; Vitting-Seerup, K.

10.1101/2022.08.29.505720 — molecular biology — Posted on 2022-09-05

3740 Event-related potential correlates of learning to produce novel foreign phonemes

Railo, H.; Varjonen, A.; Lehtonen, M.; Sikka, P.

10.1101/2022.01.18.476741 — neuroscience — Posted on 2022-09-05

3741 A model for the propagation of seizure activity in normal brain tissue

Depannemaecker, D.; Carlu, M.; Boute, J.; Destexhe, A.

10.1101/2022.02.21.481321 — neuroscience — Posted on 2022-09-05

3742 Are Machines-learning Methods More Efficient than Humans in Triaging Literature for Systematic Reviews?

Abogunrin, S.; Queiros, L.; Bednarski, M.; Sumner, M.; Baehrens, D.; Witzmann, A.

10.1101/2021.09.30.462652 — bioinformatics — Posted on 2022-09-05

3743 The mitochondrial ferredoxin-like is essential for the formation of complex I-containing respiratory supercomplexes in Arabidopsis thaliana

Röhricht, H.; Przybyla-Toscano, J.; Forner, J.; Boussardon, C.; Rouhier, N.; Keech, O.; Meyer, E. H.

10.1101/2022.09.02.506396 — plant biology — Posted on 2022-09-05

3744 Succinct k-mer Sets Using Subset Rank Queries on the Spectral Burrows-Wheeler Transform

Alanko, J. N.; Puglisi, S. J.; Vuohtoniemi, J.

10.1101/2022.05.19.492613 — bioinformatics — Posted on 2022-09-05

3745 Time-Resolved Interactome Profiling Deconvolutes Secretory Protein Quality Control Dynamics

Wright, M. T.; Timalsina, B.; Lopez, V. A. G.; Plate, L.

10.1101/2022.09.04.506558 — cell biology — Posted on 2022-09-05

3746 Structures and membrane interactions of native serotonin transporter in complexes with psychostimulants

Yang, D.; Zhao, Z.; Tajkhorshid, E.; Gouaux, E.

10.1101/2022.09.03.506477 — biophysics — Posted on 2022-09-05

3747 Development of the alpha rhythm is linked to visual white matter pathways and visual detection performance

Caffarra, S.; Kanopka, K.; Kruper, J.; Richie-Halford, A.; Roy, E.; Rokem, A.; Yeatman, J. D.

10.1101/2022.09.03.506461 — neuroscience — Posted on 2022-09-04

3748 Effects of stimulus rate and periodicity on auditory cortical entrainment to continuous sounds

Momtaz, S.; Bidelman, G. M.

10.1101/2022.09.04.506557 — neuroscience — Posted on 2022-09-04

3749 NPAS4 supports drug-cue associations and relapse-like behavior through regulation of the cell type-specific activation balance in the nucleus accumbens

Hughes, B. W.; Tsvetkov, E.; Siemsen, B. M.; Snyder, K. K.; Akiki, R. M.; Wood, D. J.; Penrod, R. D.; Scofield, M. D.; Berto, S.; Taniguchi, M.; Cowan, C. W.

10.1101/2022.09.04.506434 — neuroscience — Posted on 2022-09-05

3750 How inhibitory and excitatory inputs gate output of the inferior olive

Loyola, S.; Hoogland, T. M.; Negrello, M.; Hoedemaker, H.; Romano, V. E.; De Zeeuw, C. I.

10.1101/2022.09.04.506491 — neuroscience — Posted on 2022-09-05

3751 Aquaporin regulates cell rounding through vacuole formation during endothelial-to-hematopoietic transition

Sato, Y.; Shigematsu, M.; Shibata-Kanno, M.; Maejima, S.; Tamura, C.; Sakamoto, H.

10.1101/2022.09.03.506460 — developmental biology — Posted on 2022-09-04

3752 Dynamic allosteric networks drive adenosine A1 receptor activation and G-protein coupling

Maria Solano, M. A.; Choi, S.

10.1101/2022.08.08.502889 — biophysics — Posted on 2022-09-04

3753 G-quadruplex landscape and its regulation revealed by a new antibody capture method

Datta, S.; Patel, M.; Sathyaseelan, C.; Patel, D.; Rathinavelan, T.; Singh, U.

10.1101/2022.09.03.506459 — genomics — Posted on 2022-09-04

3754 Roles of the distinct N-terminal amino acid between H3 and H3.3 in Drosophila male germline stem cell lineage

Chandrasekhara, C.; Ranjan, R.; Urban, J. A.; Ku, W. L.; Snedeker, J.; Zhao, K.; Chen, X.

10.1101/2022.09.03.506490 — developmental biology — Posted on 2022-09-04

3755 Discovery of thyrocyte heterogeneity reveals an essential role of Notch signaling in thyroid function and mammalian homeostasis

Mosteiro, L.; Nguyen, T. T. T.; Hankeova, S.; Reichelt, M.; Vandriel, S. M.; Lai, Z.; Choudhury, F. K.; Sangaraju, D.; Kamath, B. M.; Scherl, A.; Piskol, R.; Siebel, C. W.

10.1101/2022.09.02.506441 — cell biology — Posted on 2022-09-04

3756 Organic Convolution Model of Ventral Visual Path Reproduces Curvature Selective Shape Tuning Found in Area V4

Gold, C. S.

10.1101/2022.05.03.490165 — neuroscience — Posted on 2022-09-04

3757 Cortical Circuit Mechanisms of Multimodal Temporal Pattern Discrimination

Post, S.; Mol, W.; Abu-Wishah, O.; Ali, S.; Rahmatullah, N.; Goel, A.

10.1101/2022.08.31.506133 — neuroscience — Posted on 2022-09-04

3758 SVR-based Multimodal Active Subspace Analysis for the Brain using Neuroimaging Data

Batta, I.; Abrol, A.; Calhoun, V.

10.1101/2022.07.28.501879 — neuroscience — Posted on 2022-09-04

3759 Cell type-specific basal forebrain GABAergic neuronal activity with olfactory task performance, learning, and decision-making

Hanson Moss, E. L.; Tantry, E. K.; Le, E.; Brandel-Ankrapp, K.; Arenkiel, B. R.

10.1101/2022.09.04.506524 — neuroscience — Posted on 2022-09-04

3760 Understanding emergence of antimycobacterial dose dependent resistance.

Kloprogge, F.; Ortiz Canseco, J.; Phee, L.; Sadouki, Z.; Kipper, K.; Witney, A. A.; Stoker, N.; McHugh, T. D.

10.1101/2022.09.02.506358 — pharmacology and toxicology — Posted on 2022-09-04

3761 PKCβ facilitates leukemogenesis in chronic lymphocytic leukaemia by promoting constitutive BCR-mediated signaling

Hay, J.; Tarafdar, A.; Holroyd, A.; Moka, H. A.; Dunn, K. M.; Alshayeb, A.; Lloyd, B. H.; Cassels, J.; Malik, N.; Khan, A. F.; Sou, I.; Lees, J.; Almuhanna, H. N.; Kalakonda, N.; Slupsky, J. R.; Michie, A. M.

10.1101/2022.09.04.506520 — cancer biology — Posted on 2022-09-04

3762 Combined blockade of VEGF, Angiopoietin-2, and PD1 reprograms glioblastoma endothelial cells into quasi-antigen-presenting cells

Amoozgar, Z.; Ren, J.; Wang, N.; Andersson, P.; Ferraro, G.; Rajan, S.; Lei, P.; Subudhi, S.; Kawaguchi, K.; Tay, R. E.; Gomes Dos Santos, I. L.; Huang, P.; Kim, H.-J.; Fukumura, D.; Jain, R.

10.1101/2022.09.03.506476 — cancer biology — Posted on 2022-09-04

3763 Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells

YANG, C.; Wierbilowicz, K.; Abianeh, N.; Abbas, T.; Ratan, A.; Wotton, D.; Paschal, B. M.

10.1101/2022.09.02.506406 — cancer biology — Posted on 2022-09-04

3764 A model-free Data-Driven paradigm for in situ patient-specific prediction of human brain response to ultrasound stimulation

Salahshoor, H.; Ortiz, M.

10.1101/2022.09.01.506248 — biophysics — Posted on 2022-09-04

3765 Single-Molecule Structure and Topology of Kinetoplast DNA Networks

He, P.; Katan, A.; Tubiana, L.; Dekker, C.; Michieletto, D.

10.1101/2022.09.02.506432 — biophysics — Posted on 2022-09-04

3766 Multi-scale Adaptive Differential Abundance Analysis in Microbial Compositional Data

Wang, S.

10.1101/2021.11.02.466987 — bioinformatics — Posted on 2022-09-04

3767 Mechanistic Deep Learning Framework on Cell Traits Derived from Single-Cell Mass Cytometry Data

Wang, B.; Zinkel, S. S.; Gamazon, E. R.

10.1101/2022.08.22.504669 — bioinformatics — Posted on 2022-09-04

3768 Three new genome assemblies of blue mussel lineages: North and South European Mytilus edulis and Mediterranean Mytilus galloprovincialis.

Simon, A.

10.1101/2022.09.02.506387 — genomics — Posted on 2022-09-04

3769 XerC is required for the repair of antibiotic- and immune-mediated DNA damage in Staphylococcus aureus

Ledger, E. V.; Lau, K.; Tate, E. W.; Edwards, A. M.

10.1101/2022.09.04.506505 — microbiology — Posted on 2022-09-04

3770 Evaluating microbial contaminations of alternative heating oils

Surger, M. J.; Mayer, K.; Shivaram, K.; Stibany, F.; Plum, W.; Schaeffer, A.; Eiden, S.; Blank, L. M.

10.1101/2022.09.04.506525 — microbiology — Posted on 2022-09-04

3771 Local field potentials and single unit dynamics in motor cortex of unconstrained macaques during different behavioral states

Yun, R.; Mishler, J.; Rembado, I.; Rao, R. P. N.; Perlmutter, S. I.; Fetz, E. E.

10.1101/2022.04.28.489967 — neuroscience — Posted on 2022-09-04

3772 Neuroligin-3 in Dopaminergic Circuits Promotes Behavioral and Neurobiological Adaptations to Chronic Morphine Exposure

Brandner, D. D.; Retzlaff, C. L.; Kocharian, A.; Stieve, B. J.; Mashal, M. A.; Mermelstein, P. G.; Rothwell, P. E.

10.1101/2022.03.14.484267 — neuroscience — Posted on 2022-09-04

3773 LARP1 regulates metabolism and mTORC1 activity in cancer

Chettle, J.; Dedeic, Z.; Fischer, R.; Vendrell, I.; Campo, L.; Easton, A.; Browne, M.; Morris, J.; Schwenzer, H.; Lascaux, P.; Gijsbers, R.; Pires, E.; Royston, D. J.; Ferguson, D. J. P.; Coosemans, A.; Kessler, B.; McCullagh, J.; Ahmed, A. A.; Ramadan, K.; Bushell, M.; Harris, A. L.; Goding, C. R.; Blagden, S. P.

10.1101/2022.09.04.506559 — cancer biology — Posted on 2022-09-04

3774 Structural Reorganization and Relaxation Dynamics of Axially Stressed Chromosomes

Ruben, B. S.; Brahmachari, S.; Contessoto, V. G.; Cheng, R. R.; Oliveira Junior, A. B.; Di Pierro, M.; Onuchic, J. N.

10.1101/2022.09.03.506488 — biophysics — Posted on 2022-09-04

3775 MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes

Neron, B.; Denise, R.; Coluzzi, C.; Touchon, M.; Rocha, E. P. C.; Abby, S. S.

10.1101/2022.09.02.506364 — bioinformatics — Posted on 2022-09-04

3776 RosettaDDGPrediction for high-throughput mutational scans: from stability to binding

Valentina, S.; Otamendi Laspiur, A.; Degn, K.; Arnaudi, M.; Utichi, M.; Beltrame, L.; De Menezes, D.; Orlandi, M.; Rigina, O.; Sackett, P. W.; Wadt, K.; Schmiegelow, K.; Papaleo, E.

10.1101/2022.09.02.506350 — bioinformatics — Posted on 2022-09-04

3777 A Beefy-R culture medium: replacing albumin with rapeseed protein isolates

Stout, A. J.; Rittenberg, M. L.; Shub, M.; Saad, M. K.; Mirliani, A. B.; Kaplan, D. L.

10.1101/2022.09.02.506409 — bioengineering — Posted on 2022-09-04

3778 Mechanistic analysis of a novel membrane-interacting variable loop in the pleckstrin-homology domain critical for dynamin function

Khurana, H.; Bhattacharyya, S.; Pucadyil, T.

10.1101/2022.09.03.506501 — biochemistry — Posted on 2022-09-04

3779 RTEL-1 and DNA polymerase theta promote subtelomeric DNA synthesis and telomere fusion in C. elegans

Ahmed, S.; Lister-Shimauchi, E.; Brady, M.; Frenk, S.; Harris, B.; Ortiz, A.-M. L.; Memili, A.; Nguyen, M.; Boulton, S.

10.1101/2022.09.04.506531 — genetics — Posted on 2022-09-04

3780 Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

Shapiro-Kulnane, L.; Salz, H. K.

10.1101/2022.09.04.506543 — genetics — Posted on 2022-09-04

3781 Detection and Role of Feline Apolipoprotein B mRNA-editing Enzyme Catalytic Polypeptide Subunit 3G-Like Protein in Feline Cells and Tissues

Assogba, B. D.; Chaudhary, S.; Kaur, H.; Soo, R.; Dela Cruz, M. A. P.; Assogba, J. M. G.

10.1101/2022.09.03.504613 — cell biology — Posted on 2022-09-04

3782 Production and secretion of recombinant proteins using the endotoxin-free, Gram-negative bacterium Sphingobium japonicum

Shahar, E.; Emquies, K.; Bloch, I.; Eliahu, D.; Ben Adiva, R.; Pitkovski, J.; Yadid, I.

10.1101/2022.09.04.506512 — molecular biology — Posted on 2022-09-04

3783 Pseudokinase HPO-11 inhibits nonsense-mediated decay to ensure genome stability in C. elegans

Zhao, Q.; Gromoff, E. D. v.; Yang, W.; Schwarz, J.; Schulze, E.; Warscheid, B.; Baumeister, R.; Qi, W.

10.1101/2022.09.04.506508 — molecular biology — Posted on 2022-09-04

3784 Linking mesozooplankton and SAR11 bacteria in Oxygen Deficient Zones and the open ocean

Fuchsman, C. A.; Hays, M. D.; Huanca-Valenzuela, P.; Gregory, B. P.; Plough, L. V.; Duffy, M. E.; Keil, R. G.; Peng, X.

10.1101/2022.09.04.506529 — microbiology — Posted on 2022-09-04

3785 Enhanced Effector Activity of Mediator Kinase Module Deficient CAR-T Cells

Freitas, K. A.; Belk, J. A.; Sotillo, E.; Daniel, B.; Sandor, K.; Klysz, D.; Duong, V. T.; Burdsall, K. A.; Xu, P.; Malipatlolla, M.; Donovan, M. G.; Weber, E. W.; Majzner, R. G.; Chang, H. Y.; Espinosa, J. M.; Satpathy, A. T.; Mackall, C. L.

10.1101/2022.09.02.506235 — immunology — Posted on 2022-09-04

3786 Systematic Epigenome Editing Captures the Context-dependent Instructive Function of Chromatin Modifications

Policarpi, C.; Munafo, M.; Tsagkris, S.; Carlini, V.; Hackett, J. A.

10.1101/2022.09.04.506519 — synthetic biology — Posted on 2022-09-04

3787 Simple, low-cost production of DNA MS2 virus-like particles as molecular diagnostic controls

Crone, M. A.; Freemont, P. S.

10.1101/2022.09.04.506540 — synthetic biology — Posted on 2022-09-04

3788 Zinc Fingers and Homeoboxes 2 is Required for Diethylnitrosamine-induced Liver Tumor Formation in C57BL/6 Mice

Jiang, J.; Turpin, C.; Qiu, G.; Xu, M.; Lee, E.; Hinds, T. D.; Peterson, M. L.; Spear, B. T.

10.1101/2022.09.02.506400 — cancer biology — Posted on 2022-09-04

3789 Microphysiological vascular malformation model reveals a role of dysregulated Rac1 and mTORC1/2 in lesion formation.

Aw, W. Y.; Cho, C.; Wang, H.; Cooper, A. H.; Doherty, E. L.; Rocco, D.; Huang, S. A.; Kubik, S.; Whitworth, C. P.; Armstrong, R.; Hickey, A. J.; Griffith, B.; Kutys, M. L.; Blatt, J.; Polacheck, W. J.

10.1101/2022.09.03.506415 — bioengineering — Posted on 2022-09-04

3790 DNA damage-induced YTHDC1 O-GlcNAcylation promotes homologous recombination by enhancing N6-methyladenosine binding

Li, M.; Li, J.; Yuan, A.; Dong, W.; Dong, S.; Yang, Y.-G.; Wang, Y.; Wu, C.; Li, J.

10.1101/2022.09.03.506498 — biochemistry — Posted on 2022-09-04

3791 Whole-genome duplication reshaped adaptive evolution in a relict plant species, Cyclocarya paliurus

Yinquan, Q.; Xulan, S.; Ziyan, Z.; Yanhao, Y.; Guoliang, B.; Wenling, W.; Li, L.; Li, T.; Shengcheng, Z.; Qian, W.; Dejin, X.; Xuequn, C.; Zhenyang, L.; Yibin, W.; Jian, Q.; Wanxia, Y.; Caowen, S.; Xiangxiang, F.; Xingtan, Z.; Shengzuo, F.

10.1101/2022.09.04.506500 — genetics — Posted on 2022-09-04

3792 The anti-caspase 1 inhibitor VX-765 reduces immune activation, CD4+ T cell depletion, viral load and total HIV-1 DNA in HIV-1 infected humanized mice

Amand, M.; Adams, P.; Schober, R.; Iserentant, G.; Servais, J.-Y.; Moutschen, M.; Seguin-Devaux, C.

10.1101/2022.09.01.502964 — immunology — Posted on 2022-09-04

3793 Early detection of late blight in potato by whole-plant redox imaging

Hipsch, M.; Michael, Y.; Lampl, N.; Sapir, O.; Cohen, Y.; Helman, D.; Rosenwasser, S.

10.1101/2022.09.04.506513 — plant biology — Posted on 2022-09-04

3794 Slow and not so furious: de novo stomatal pattern formation during plant embryogenesis

Smit, M.; Vaten, A.; Mair, A.; Northover, C.; Bergmann, D.

10.1101/2022.09.02.506417 — plant biology — Posted on 2022-09-04

3795 The tea plant (Camellia sinensis) FLOWERING LOCUS C-like gene CsFLC1 is correlated with bud dormancy and triggers early flowering in Arabidopsis

Liu, Y.; Dreni, L.; Zhang, H.; Zhang, X.; Li, N.; Zhang, K.; Di, T.; Wang, L.; Yang, Y.; Hao, X.; Wang, X.

10.1101/2022.09.02.506372 — plant biology — Posted on 2022-09-04

3796 Dynamic regulation of gonadal homeostasis across the lifespan of the naturally short-lived African turquoise killifish

Teefy, B. B.; Adler, A.; Xu, A.; Singh, P. P.; Benayoun, B. A.

10.1101/2022.09.02.506427 — genomics — Posted on 2022-09-04

3797 Unravelling drivers of local adaptation through Evolutionary Functional-Structural Plant modelling

de Vries, J.; Fior, S.; Paalsson, A.; Widmer, A.; Alexander, J. M.

10.1101/2022.09.02.506361 — evolutionary biology — Posted on 2022-09-04

3798 Metabolic integration of spectral and chemical cues mediating plant responses to competitors and herbivores

Chauta, A.; Kessler, A.

10.1101/2022.09.02.506388 — ecology — Posted on 2022-09-04

3799 Ecological corridors homogenize plant root endospheric mycobiota

Hu, J.; Vandenkoornhuyse, P.; Khalfallah, F.; Causse-Vedrines, R.; Mony, C.

10.1101/2022.09.02.506380 — ecology — Posted on 2022-09-04

3800 Characterization of b-value dependent T2 relaxation rates for probing neurite microstructure

Ning, L.; Westin, C.-F.; Rathi, Y.

10.1101/2022.09.02.506440 — neuroscience — Posted on 2022-09-04

3801 Neural responses to movie naturalistic stimuli are related to listening demand in cochlear implant users

Xiu, B.; Paul, B. T.; Chen, J. M.; Le, T. N.; Lin, V. Y.; Dimitrijevic, A.

10.1101/2022.09.02.506424 — neuroscience — Posted on 2022-09-04

3802 Compartmentation of putrescine synthesis in plants

Joshi, K.; Ahmed, S.; Ge, L.; Phuntumart, V.; Kalinoski, A.; Morris, P. F.

10.1101/2022.09.03.506421 — plant biology — Posted on 2022-09-04

3803 Human Dectin-1 is O-glycosylated and serves as a ligand for C-type lectin receptor CLEC-2

Haji, S.; Ito, T.; Guenther, C.; Nakano, M.; Shimizu, T.; Mori, D.; Chiba, Y.; Tanaka, M.; Mishra, S. K.; Willment, J. A.; Brown, G. D.; Nagae, M.; Yamasaki, S.

10.1101/2022.09.02.506356 — immunology — Posted on 2022-09-04

3804 Developmental Basis of SHH Medulloblastoma Heterogeneity

Gold, M. P.; Ong, W.; Masteller, A. M.; Galindo, J. A.; Park, N. R.; Saurez, R. A.; Vladoiu, M. C.; Donovan, L. K.; Walker, A. D.; Benetatos, J.; Garzia, L.; Wechsler-Reya, R. J.; Mesirov, J. P.; Korshunov, A.; Pomeroy, S. L.; Davidson, S. M.; Cotter, J. A.; Taylor, M. D.; Fraenkel, E.

10.1101/2022.09.02.506110 — cancer biology — Posted on 2022-09-04

3805 Release of lipid nanodiscs from charged nano-droplets in the electrospray ionization process revealed by microsecond atomistic molecular dynamics simulations

Wang, B.; Tieleman, D. P.

10.1101/2022.09.01.506154 — biophysics — Posted on 2022-09-04

3806 Whole-Genome Sequencing and Comparative Genomic Analysis of Potential Biotechnological Strains of Trichoderma harzianum, Trichoderma atroviride, and Trichoderma reesei

Rosolen, R. R.; Horta, M. A. C.; de Azevedo, P. H. C.; da Silva, C. C.; Sforca, D. A.; Goldman, G. H.; de Souza, A. P.

10.1101/2022.02.11.479986 — genomics — Posted on 2022-09-04

3807 Regulation of neuropathic pain by microglial Orai1 channels

Tsujikawa, S.; DeMeulenaere, K. E.; Ceneno, M. V.; Ghazisaeidi, S.; Martin, M. E.; Tapies, M. R.; Maneshi, M. M.; Yamashita, M.; Stauderman, K. A.; Apkarian, A. V.; Salter, M. W.; Prakriya, M.

10.1101/2022.09.02.506250 — neuroscience — Posted on 2022-09-04

3808 Arc ubiquitination regulates endoplasmic reticulum-mediated Ca2+ release and CaMKII signaling

Ghane, M. A.; Allen, Z. D.; Miller, C. L.; Dong, B.; Fang, N.; Yang, J. J.; Mabb, A. M.

10.1101/2022.09.02.506383 — neuroscience — Posted on 2022-09-04

3809 Abscisic Acid Drives Stomatal Closure through Increases in Hydrogen Peroxide in Mitochondria

Postliglione, A. E.; Muday, G. K.

10.1101/2022.01.11.475946 — plant biology — Posted on 2022-09-04

3810 Tracking subject's strategies in behavioural choice experiments at trial resolution

Maggi, S.; Hock, R. M.; O'Neill, M.; Buckley, M. J.; Moran, P. M.; Bast, T.; Sami, M.; Humphries, M. D.

10.1101/2022.08.30.505807 — neuroscience — Posted on 2022-09-04

3811 Single-cell analysis of bovine muscle-derived cell types for cultured meat production

Messmer, T.; Dohmen, R. G.; Schaeken, L.; Melzener, L.; Hueber, R.; Godec, M.; Post, M. J.; Flack, J. E.

10.1101/2022.09.02.506369 — cell biology — Posted on 2022-09-04

3812 Assembly of neuron- and radial glial cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons

Mubuchi, A.; Takechi, M.; Nishio, S.; Matsuda, T.; Sato, C.; Kitajima, K.; Kitagawa, H.; Miyata, S.

10.1101/2022.09.03.506497 — neuroscience — Posted on 2022-09-04

3813 Transcriptome and chromatin accessibility landscapes across 25 distinct human brain regions expand the susceptibility gene set for neuropsychiatric disorders

Dong, P.; Bendl, J.; Misir, R.; Shao, Z.; Edelstien, J.; Davis, D. A.; Haroutunian, V.; Scott, W. K.; Acker, S.; Lawless, N.; Hoffman, G. E.; Fullard, J. F.; Roussos, P.

10.1101/2022.09.02.506419 — neuroscience — Posted on 2022-09-04

3814 The Role of the Posterior Medial Network in Language Comprehension: Dissociating Construction of Episodic versus Semantic Representations

Branzi, F. M.; Lambon Ralph, M.

10.1101/2022.09.03.506471 — neuroscience — Posted on 2022-09-04

3815 Is evolutionary conservation a useful predictor for cancer long noncoding RNAs? Insights from the Cancer lncRNA Census 3

Vancura, A.; Gutierrez, A. H.; Hennig, T.; Pulido-Quetglas, C.; Slack, F.; Johnson, R.; Haefliger, S.

10.1101/2022.09.01.506261 — cancer biology — Posted on 2022-09-04

3816 Potent, Gut-Restricted Inhibitors of Divalent Metal Transporter 1 (DMT1): Preclinical Efficacy Against Iron Overload and Safety Evaluation

Cutts, A. J.; Chowdhury, S.; Ratkay, L.; Eyers, M.; Young, C.; Namdari, R.; Cadieux, J.; Chahal, N.; Grimwood, M.; Zhang, Z.; Lin, S.; Tietjen, I.; Xie, Z.; Robinette, L.; Sojo, L.; Waldbrook, M.; Hayden, M. R.; Mansour, T.; Pimstone, S.; Goldberg, Y. P.; Webb, M.; Cohen, C. J.

10.1101/2022.09.01.506269 — pharmacology and toxicology — Posted on 2022-09-04

3817 Hydrostatic pressure and lateral actomyosin tension control stretch and tension of the basement membrane in epithelia

Guerra Santillan, K. Y.; Dahmann, C.; Fischer-Friedrich, E.

10.1101/2022.09.02.506324 — biophysics — Posted on 2022-09-04

3818 Tailored machine learning models for functional RNA detection in genome-wide screens

Klapproth, C.; Zoeztsche, S.; Kuehnl, F.; Findeiss, S.; Fallmann, J.; Stadler, P. F.

10.1101/2022.09.01.506220 — bioinformatics — Posted on 2022-09-04

3819 Size-tunable ICG-based contrast agent platform for targeted near-infrared photoacoustic imaging

Singh, S.; Giammanco, G.; Hu, C.-H.; Bush, J.; Cordova, L. S.; Lawrence, D. J.; Moran, J. L.; Chitnis, P. V.; Veneziano, R.

10.1101/2022.09.01.506234 — bioengineering — Posted on 2022-09-04

3820 Length-limitation of astral microtubules orients cell divisions in intestinal crypts

Saleh, J.; Fardin, M.-A.; Frenoy, O.; Soleilhac, M.; Gaston, C.; Cui, H.; Dang, T.; Gaudin, N.; Vincent, A.; MINC, N.; Delacour, D.

10.1101/2022.09.02.506333 — developmental biology — Posted on 2022-09-04

3821 Chemoenzymatic Measurement of Cell-surface Glycan in Single-cell Multiomics: LacNAc as an Example

Yu, W.; Zhao, X.; Jalloh, A. S.; Zhao, Y.; Dinner, B.; Yang, Y.; Ouyang, S.; Li, Y.; Tian, T.; Zhao, Z.; Yang, R.; Chen, M.; Lauvau, G.; Guo, Z.; Wu, P.; Li, J. P.

10.1101/2022.09.01.506123 — immunology — Posted on 2022-09-04

3822 Energy Crisis after Inter-System Mitochondria Transfer is the Direct Cause of Death by Sepsis

Tang, M.

10.1101/2022.09.01.505533 — immunology — Posted on 2022-09-04

3823 Altered tau in rTg4510 mice after a single interfaced CHIMERA traumatic brain injury

Cheng, W. H.; Cheung, H.; Kang, A.; Fan, J.; Cooper, J.; Anwer, M.; Barron, C.; Wilkinson, A.; Hu, G.; Yue, J.; Cripton, P. A.; Vocadlo, D.; Wellington, C. L.

10.1101/2022.09.01.506145 — neuroscience — Posted on 2022-09-04

3824 The locus coeruleus mediates behavioral flexibility

McBurney-Lin, J.; Yang, H.

10.1101/2022.09.01.506286 — neuroscience — Posted on 2022-09-04

3825 Phosphate starvation response precedes abscisic acid response in response to mild drought in plants

Nagatoshi, Y.; Ikazaki, K.; Mizuno, N.; Kobayashi, Y.; Fujii, K.; Ogiso-Tanaka, E.; Ishimoto, M.; Yasui, Y.; Oya, T.; Fujita, Y.

10.1101/2021.07.28.453724 — plant biology — Posted on 2022-09-04

3826 Effect of 15 days hindlimb unloading on baroreflex sensitivity, Hear rate variability and Carotid artery structure in rats

Bhatnaagar, A.; Deepak, K. K.; Roy, A.; Sharma, B.; Roy, A.; Singh, A.; Netam, R.

10.1101/2022.09.02.506352 — physiology — Posted on 2022-09-04

3827 A living biobank of canine mammary tumor organoids as a comparative model for human breast cancer

Inglebert, M.; Dettwiler, M.; Hahn, K.; Letko, A.; Droegemueller, C.; Doench, J. G.; Brown, A.; Memari, Y.; Davies, H.; Degasperi, A.; Nik-Zainal, S.; Rottenberg, S.

10.1101/2022.09.02.505845 — cancer biology — Posted on 2022-09-03

3828 Construction of epithelial-mesenchymal transition related miRNAs signatures as prognostic biomarkers in gastric cancer patients

Xiao, J.; Zhang, F.; Liu, W.; Zang, W.

10.1101/2022.09.02.506322 — cancer biology — Posted on 2022-09-04

3829 Enhancing Robustness, Precision and Speed of Traction Force Microscopy with Machine Learning

Kratz, F. S.; Moellerherm, L.; Kierfeld, J.

10.1101/2022.09.02.506331 — biophysics — Posted on 2022-09-03

3830 Var I Decrypt: a novel and user-friendly tool to explore and prioritize variants in whole-exome sequencing data

Salma, M.; Alaterre, E.; Moreaux, J.; Soler, E.

10.1101/2022.09.02.506346 — bioinformatics — Posted on 2022-09-03

3831 Combining molecular dynamics simulations and scoring method to computationally model ubiquitylated linker histones in chromatosomes

Sawade, K.; Peter, C.; Marx, A.; Kukharenko, O.

10.1101/2022.09.01.506295 — bioinformatics — Posted on 2022-09-04

3832 Direct electricity production from green onion's roots

Shlosberg, Y.

10.1101/2022.09.01.506267 — bioengineering — Posted on 2022-09-03

3833 Gas modulating microcapsules for spatiotemporal control of hypoxia

molley, t. G.; Jiang, S.; Kopecky, C.; Ranaweera, C. D.; Jalandhra, G. K.; Rnjak-Kovacina, J.; Kilian, K. A.

10.1101/2022.09.02.506302 — bioengineering — Posted on 2022-09-04

3834 Contrasting genomic evolution between domesticated and wild Kluyveromyces lactis yeast populations

Friedrich, A.; Gounot, J.-S.; Tsouris, A.; Bleykasten, C.; Freel, K.; Caradec, C.; Schacherer, J.

10.1101/2022.09.02.506316 — genomics — Posted on 2022-09-03

3835 Epistatic effects between amino acid insertions and substitutions mediate toxin-resistance of vertebrate Na+,K+-ATPases

Mohammadi, S.; Özdemir, H. I.; Ozbek, P.; Sumbul, F.; Stiller, J.; Deng, Y.; Crawford, A. J.; Rowland, H. M.; Storz, J. F.; Andolfatto, P.; Dobler, S.

10.1101/2022.09.01.506169 — evolutionary biology — Posted on 2022-09-04

3836 Identifying the potential for sustainable human wildlife coexistence by integrating willingness to coexist with habitat suitability models

Vogel, S. M.; Vasudev, D.; Ogutu, J. O.; Taek, P.; Berti, E.; Goswami, V. R.; Kaelo, M.; Buitenwerf, R.; Munk, M.; Li, W.; Wall, J.; Gelete, D. C.; Amoke, I.; Odingo, A.; Svenning, J.-C.

10.1101/2022.09.02.506181 — ecology — Posted on 2022-09-03

3837 Altered litter and cellulose decomposition across an anthropogenic habitat modification gradient in Sulawesi, Indonesia

Holle, M. J. M.; Lewis, O. T.

10.1101/2022.09.02.506341 — ecology — Posted on 2022-09-03

3838 Antibiotic effects on microbial communities are modulated by resource competition

Newton, D. P.; Ho, P.-Y.; Huang, K.

10.1101/2022.09.01.506215 — ecology — Posted on 2022-09-04

3839 Quantitative proteomics and lipidomics of TFG-deficient B cells provide insights into mechanisms of autophagic flux and plasma cell biology

Steinmetz, T. D.; Reimann, L.; Schulz, S. R.; Urbanczyk, S.; Thomas, J.; Himmelreich, A.-K.; Golombek, F.; Castiglione, K.; Brodesser, S.; Warscheid, B.; Mielenz, D.

10.1101/2022.09.01.506221 — immunology — Posted on 2022-09-03

3840 WDFY4 deficiency in NOD mice abrogates autoimmune diabetes and insulitis

Ferris, S. T.; Chen, J.; Ohara, R. A.; Wu, R.; Kim, S.; Liu, T.; Murphy, T.; Murphy, K. M.

10.1101/2022.09.02.506326 — immunology — Posted on 2022-09-03

3841 Alpha oscillations reflect similar mapping mechanisms for localizing touch on hands and tools

Fabio, C.; Salemme, R.; Farne, A.; Miller, L.

10.1101/2022.09.01.506165 — neuroscience — Posted on 2022-09-03

3842 Neural Adaptation and Fractional Dynamics as a Window to Underlying Neural Excitability

Lundstrom, B.; Richner, T.

10.1101/2022.09.01.506146 — neuroscience — Posted on 2022-09-03

3843 Dissociated amplitude and phase effects of alpha oscillation in a nested structure of rhythm- and sequence-based temporal expectation

Su, Z.; Zhou, X.; Wang, L.

10.1101/2022.09.01.506156 — neuroscience — Posted on 2022-09-03

3844 Balancing true and false detection of intermittent sensory targets by adjusting the inputs to the evidence accumulation process

Geuzebroek, A. C.; Craddock, H.; O'Connell, R. G.; Kelly, S. P.

10.1101/2022.09.01.505650 — neuroscience — Posted on 2022-09-03

3845 Perception as a hierarchical competition: a model that differentiates imagined, veridical, and hallucinated percepts

Sulfaro, A. A.; Robinson, A. K.; Carlson, T. A.

10.1101/2022.09.02.506121 — neuroscience — Posted on 2022-09-03

3846 Sophorolipid Candidates Demonstrate Cytotoxic Efficacy Against 2D and 3D Breast Cancer Models

Roberge, C. L.; Miceli, R. T.; Murphy, L. R.; Kingsley, D. M.; Gross, R. A.; Corr, D. T.

10.1101/2022.09.01.506226 — pharmacology and toxicology — Posted on 2022-09-03

3847 Combating pancreatic cancer with ovarian cancer cells

lin, x.; Cui, C.; Cui, Q.

10.1101/2022.09.01.506158 — cancer biology — Posted on 2022-09-03

3848 Novel Laser Capture Microdissection-Proteomic Analysis Identifies Spatially Distinct Extracellular Matrix Signatures in the Core and Infiltrating Edge of Human Glioblastoma.

Pedley, R.; Prescott, D. T.; Appleton, E.; Dingle, L.; Minshull, J.; D'Urso, P. I.; Djoukhadar, I.; Gilmore, A. P.; Roncaroli, F.; Swift, J.

10.1101/2022.09.01.506199 — cancer biology — Posted on 2022-09-03

3849 A model-free Data-Driven paradigm for in situ patient-specific prediction of human brain response to ultrasound stimulation

Salahshoor, H.; Ortiz, M.

10.1101/2022.09.01.506248 — biophysics — Posted on 2022-09-03

3850 Mechanistic Deep Learning Framework on Cell Traits Derived from Single-Cell Mass Cytometry Data

Wang, B.; Zinkel, S. S.; Gamazon, E. R.

10.1101/2022.08.22.504669 — bioinformatics — Posted on 2022-09-03

3851 ggcoverage: an R package to visualize and annotate genome coverage for various NGS data

Song, Y.; Wang, J.

10.1101/2022.09.01.503744 — bioinformatics — Posted on 2022-09-03

3852 FAS: Assessing the similarity between proteins using multi-layered feature architectures

Dosch, J.; Bergmann, H.; Tran, V.; Ebersberger, I.

10.1101/2022.09.01.506207 — bioinformatics — Posted on 2022-09-03

3853 LncDLSM: Identification of Long Non-coding RNAs with Deep Learning-based Sequence Model

Wang, Y.; Zhao, P.; Du, H.; Cao, Y.; Peng, Q.; Fu, L.

10.1101/2022.09.02.506180 — bioinformatics — Posted on 2022-09-03

3854 SpaCeNet: Spatial Cellular Networks from omics data

Lück, N.; Lohmayer, R.; Solbrig, S.; Schrod, S.; Wipfler, T.; Shutta, K. H.; Guebila, M. B.; Schäfer, A.; Beissbarth, T.; Zacharias, H. U.; Oefner, P. J.; Quackenbush, J.; Altenbuchinger, M.

10.1101/2022.09.01.506219 — bioinformatics — Posted on 2022-09-03

3855 Targeted degradation of microtubule-associated protein tau using an engineered nanobody-E3 ubiquitin ligase adapter fusion

Wang, S.; Jiang, S.; Zheng, G.; Cho, Y. K.

10.1101/2022.09.01.506229 — bioengineering — Posted on 2022-09-03

3856 Sensory uncertainty punctuates motor learning independently of movement error when both feedforward and feedback control processes are engaged

Hewitson, C. L.; Kaplan, D. M.; Crossley, M.

10.1101/2022.09.01.506147 — animal behavior and cognition — Posted on 2022-09-03

3857 An endogenous lentivirus in the germline of a rodent.

Kambol, R.; Gatseva, A.; Gifford, R. J.

10.1101/2022.09.01.506243 — evolutionary biology — Posted on 2022-09-03

3858 Recovering birds and mammals across Europe continue to be negatively impacted by threats but benefit from conservation measures

Gray, C.; McRae, L.; Deinet, S.; Ledger, S. E. H.; Benham, C.; Burfield, I.; Eaton, M.; Scott-Gatty, K.; Puleston, H.; Rutherford, C.; Staneva, A.; Schepers, F.; Freeman, R.

10.1101/2022.09.01.506271 — ecology — Posted on 2022-09-03

3859 Myelin plasticity in ventral tegmental area is required for opioid reward

Yalcin, B.; Pomrenze, M. B.; Malacon, K.; Chau, I. J.; Taylor, K. R.; Ni, L.; Contreras-Esquivel, D.; Malenka, R. C.; Monje, M.

10.1101/2022.09.01.506263 — neuroscience — Posted on 2022-09-03

3860 A Principal Odor Map Unifies Diverse Tasks in Human Olfactory Perception

Lee, B. K.; Mayhew, E. E.; Sanchez-Lengeling, B.; Wei, J. N.; Qian, W. W.; Little, K.; Andres, M.; Nguyen, B. B.; Moloy, T.; Parker, J. K.; Gerkin, R. C.; Mainland, J. D.; Wiltschko, A. B.

10.1101/2022.09.01.504602 — neuroscience — Posted on 2022-09-03

3861 Imaging through Windansee electrode arrays reveals a small fraction of local neurons following surface MUA

Thunemann, M.; Hossain, L.; Ness, T. V.; Rogers, N.; Lee, K.; Lee, S.-H.; Kılıc, K.; Oh, H.; Economo, M. N.; Gilja, V.; Einevoll, G.; Dayeh, S.; Devor, A.

10.1101/2022.09.01.506113 — neuroscience — Posted on 2022-09-03

3862 IL-10 inhibits STAT1-dependent macrophage accumulation during microbiota-induced colitis

Patik, I.; Redhu, N. S.; Eran, A.; Bao, B.; Nandy, A.; Tang, Y.; El Sayed, S.; Shen, Z.; Glickman, J.; Fox, J. G.; Snapper, S.; Horwitz, B. H.

10.1101/2022.09.01.505766 — immunology — Posted on 2022-09-03

3863 Gell: A GPU-powered 3D hybrid simulator for large-scale multicellular system

Du, J.; Zhou, Y.; Jin, L.; Sheng, K.

10.1101/2022.09.01.506296 — systems biology — Posted on 2022-09-03

3864 Two-Dimensional-Dwell-Time Analysis of Ion Channel Gating using High Performance Computing Clusters

Oikonomou, E.; Gruber, T.; Chandra, A. R.; Hoeller, S.; Alzheimer, C.; Wellein, G.; Huth, T.

10.1101/2022.09.01.506168 — physiology — Posted on 2022-09-03

3865 Intra-islet glucagon signalling regulates pulsatile insulin secretion and glucose homeostasis

Suba, K.; Patel, Y.; Alonso, A. M.; Roberts, A.; Hansen, B.; Norton, M.; Shrewsbury, J.; Kwok, R.; Kalogianni, V.; Chen, S.; Liu, X.; Rutter, G. A.; Jones, B.; Minnion, J.; Owen, B. M.; Distaso, W.; Drucker, D. J.; Tan, T. M.; Bloom, S. R.; Murphy, K.; Salem, V.

10.1101/2022.09.01.506223 — physiology — Posted on 2022-09-03

3866 A comparative 'omics' approach for prediction of candidate Strongyloides stercoralis diagnostic coproantigens

Marlais, T.; Bickford-Smith, J.; Talavera-Lopez, C.; Le, H.; Chowdhury, F.; Miles, M. A.

10.1101/2022.09.01.506149 — bioinformatics — Posted on 2022-09-03

3867 Random and natural non-coding RNA have similar structural motif patterns but can be distinguished by bulge, loop, and bond counts

Ghaddar, F.; Dingle, K.

10.1101/2022.09.01.506257 — evolutionary biology — Posted on 2022-09-03

3868 Divergent microbial traits influence the transformation of living versus dead root inputs to soil carbon

Sokol, N.; Foley, M.; Blazewicz, S. J.; Battacharyya, A.; Estera-Molina, K.; Firestone, M. K.; Greenlon, A.; Hungate, B. A.; Kimbrel, J.; Liquet, J.; Lafler, M.; Marple, M.; Nico, P.; Slessarev, E.; Pett-Ridge, J.

10.1101/2022.09.02.506384 — ecology — Posted on 2022-09-03

3869 Modeling ecological communities when composition is manipulated experimentally

Skwara, A.; Lemos-Costa, P.; Miller, Z. R.; Allesina, S.

10.1101/2022.05.12.491213 — ecology — Posted on 2022-09-03

3870 Motion of single molecular tethers reveals dynamic subdomains at ER-mitochondria contact sites

Obara, C. J.; Nixon-Abell, J.; Moore, A. S.; Riccio, F.; Hoffman, D. P.; Shtengel, G.; Xu, C. S.; Schaefer, K.; Pasolli, H. A.; Masson, J.-B.; Hess, H. F.; Calderon, C. P.; Blackstone, C.; Lippincott-Schwartz, J.

10.1101/2022.09.03.505525 — cell biology — Posted on 2022-09-03

3871 Temperature affects the host range of Rhabdochlamydia porcellionis and the infectivity of Waddlia chondrophila and Chlamydia trachomatis elementary bodies

Marquis, B.; Ardissone, S.; Greub, G.

10.1101/2022.09.02.506449 — microbiology — Posted on 2022-09-03

3872 Adenovirus 14p1 induced changes in miRNA expression increases lung immunopathogenesis

McIndoo, E. R.; Wood, E.; Kuffel, G.; Zilliox, M. J.; Radke, J. R.

10.1101/2022.09.03.506485 — microbiology — Posted on 2022-09-03

3873 In silico conformational features of botulinum toxins A1 and E1 according to the intraluminal acidification

Cottone, G.; Chiodo, L.; Maragliano, L.; Popoff, M.-R.; Rasetti-Escargueil, C.; Lemichez, E.; Malliavin, T. E.

10.1101/2022.09.01.506163 — neuroscience — Posted on 2022-09-03

3874 Cortical Circuit Mechanisms of Multimodal Temporal Pattern Discrimination

Post, S.; Mol, W.; Abu-Wishah, O.; Ali, S.; Rahmatullah, N.; Goel, A.

10.1101/2022.08.31.506133 — neuroscience — Posted on 2022-09-03

3875 Outcome of Crash Course Training on Protein Structure Prediction with Artificial Intelligence

Balamurugan, D.; Dougherty, M.; Lubin, J.; Arias, P.; Chang, J.; Dalenberg, K.; Kholodovych, V.; Zelzion, E.; Khare, S.; von Oehsen, J. B.; Zwick, M. E.; Burley, S. K.

10.1101/2022.09.01.506222 — scientific communication and education — Posted on 2022-09-03

3876 Effect of time spent on active learning on exam performance: A controlled case study on a course with different instructors but identical teaching materials

Cen, X.; Lee, R. J.; Maloy, J. P.; Owens, M. T.

10.1101/2022.09.01.506238 — scientific communication and education — Posted on 2022-09-03

3877 Elevated levels of lamin A promote HR and NHEJ-mediated repair mechanisms in etoposide-treated ovarian cancer cells

Sengupta, D.; SENGUPTA, K.

10.1101/2022.09.02.506330 — cancer biology — Posted on 2022-09-03

3878 An Arg/Ala-Rich Helix in the N-Terminal Region of M. tuberculosis FtsQ Anchors FtsZ to Membranes

Escobar, C. A.; Dey, S.; Smrt, S. T.; Cross, T. A.; Zhou, H.-X.

10.1101/2022.09.02.506397 — biophysics — Posted on 2022-09-03

3879 Molecular Dynamics Simulations Show How Antibodies May Rescue HIV-1 Mutants Incapable of Infecting Host Cells

Rajendra, D.; Maroli, N.; Dixit, N. M.; Maiti, P. K.

10.1101/2022.09.02.506285 — biophysics — Posted on 2022-09-03

3880 Deep autoregressive generative models capture the intrinsics embedded in T-cell receptor repertoires

Jiang, Y.; Li, S. C.

10.1101/2022.09.01.505405 — bioinformatics — Posted on 2022-09-03

3881 A deep learning and digital archaeology approach for mosquito repellent discovery

Wei, J. N.; Vlot, M.; Sanchez-Lengeling, B.; Lee, B. K.; Berning, L.; Vos, M. W.; Henderson, R. W.; Qian, W. W.; Ando, D. M.; Groetsch, K. M.; Gerkin, R. C.; Wiltschko, A. B.; Dechering, K. J.

10.1101/2022.09.01.504601 — bioengineering — Posted on 2022-09-03

3882 Structural rearrangements of a caspase-like protease TPR-CHAT govern virus-host discrimination during type III-E CRISPR-Caspase immunity

Cui, N.; Zhang, J.-T.; Li, Z.; Liu, X.-Y.; Wang, C.; Huang, H.; Jia, N.

10.1101/2022.09.03.506347 — biochemistry — Posted on 2022-09-03

3883 Structural basis of substrate recognition by human tRNA splicing endonuclease TSEN

Sekulovski, S.; Susac, L.; Stelzl, L. S.; Tampe, R.; Trowitzsch, S.

10.1101/2022.09.03.506465 — biochemistry — Posted on 2022-09-03

3884 Epistasis decreases with increasing antibiotic pressure but not temperature

Ghenu, A.-H.; Amado, A.; Gordo, I.; Bank, C.

10.1101/2022.09.01.506172 — evolutionary biology — Posted on 2022-09-03

3885 Multiple climate change factors jointly increased the competitiveness of a C4 grass against its C3 competitor

Hsu, G.-C.; Ke, P.-J.; Ho, C.-K.

10.1101/2022.09.01.506280 — ecology — Posted on 2022-09-03

3886 Extensive cellular multitasking within Bacillus subtilis biofilms

Yannarell, S. M.; Beaudoin, E. S.; Talley, H. S.; Schoenborn, A. A.; Orr, G.; Anderton, C. R.; Chrisler, W. B.; Shank, E. A.

10.1101/2022.09.02.506450 — microbiology — Posted on 2022-09-03

3887 LRRK2-G2019S SYNERGIZES WITH AGEING AND LOW-GRADE INFLAMMATION TO PROMOTE GUT AND PERIPHERAL IMMUNE CELL ACTIVATION THAT PRECEDE NIGROSTRIATAL DEGENERATION

Giachino, C.; Tirolo, C.; Caniglia, S.; Serapide, M. F.; L'Episcopo, F.; Bertoli, F.; Giuliano, C.; Mearelli, M.; Jakobi, M.; Schneiderhan-Marra, N.; Deleidi, M.; Marchetti, B.

10.1101/2022.09.01.505977 — neuroscience — Posted on 2022-09-03

3888 TRPA1 analgesia is mediated by kappa opioid receptors

Semizoglou, E.; Gentry, C.; Vastani, N.; Stucky, C. L.; Andersson, D. A.; Bevan, S.

10.1101/2022.09.01.506151 — neuroscience — Posted on 2022-09-03

3889 Membrane cholesterol regulates inhibition and substrate transport by the glycine transporter, GlyT2

Frangos, Z. J.; Wilson, K. A.; Aitken, H. M.; Cantwell Chater, R.; Vandenberg, R. J.; O'Mara, M. L.

10.1101/2022.08.31.506132 — neuroscience — Posted on 2022-09-03

3890 Endogenous tagging of Unc-13 reveals nanocluster reorganization at active zones during presynaptic homeostatic potentiation

Dannhäuser, S.; Mrestani, A.; Gundelach, F.; Pauli, M.; Komma, F.; Kollmannsberger, P.; Sauer, M.; Heckmann, M.; Paul, M.

10.1101/2022.08.31.506141 — neuroscience — Posted on 2022-09-03

3891 Role of astroglial ACBP in energy metabolism flexibility and feeding responses to metabolic challenges in male mice

Bouyakdan, K.; Manceau, R.; Robb, J. L.; Rodaros, D.; Fulton, S.; Alquier, T.

10.1101/2022.09.01.506231 — physiology — Posted on 2022-09-03

3892 Identification of a novel HASPIN inhibitor and its synergism with the PLK1 inhibitor

Kwon, E.-J.; Mashelkar, K.; Seo, J.; Shin, Y.; Sung, K.; Jang, S. C.; Cheon, S. W.; Lee, H.; Han, B. W.; Jeong, L. S.; Cha, H.-J.

10.1101/2022.09.01.506282 — pharmacology and toxicology — Posted on 2022-09-03

3893 In vivo CRISPR screen defines Slc25a37 as an organ-specific regulator of antioxidant metabolism in metastasis

Cuadros, A. M.; Fernandez-Garcia, J.; Planque, M.; Altea-Manzano, P.; Schalley, T.; Vermeire, I.; Broekaert, D.; Wu, Q.; Van Brussel, T.; Leduc, S.; Maetens, M.; Nguyen, H.-L.; Van Baelen, K.; Darzi, N.; Floris, G.; Wildiers, H.; Desmedt, C.; Lambrechts, D.; Fendt, S.-M.

10.1101/2022.09.03.506468 — cancer biology — Posted on 2022-09-03

3894 Treatment-mediated selection of lethal prostate cancer clones defined by copy number architectures

Hasan, A. M. M.; Cremaschi, P.; Wetterskog, D.; Jayaram, A.; Wong, S. Q.; Williams, S.; Pasam, A.; Trigos, A.; Trujillo, B.; Grist, E.; Friedrich, S.; Vainauskas, O.; Parry, M.; Ismail, M.; Devlies, W.; Wingate, A.; Lise, S.; Sandhu, S.; Attard, G.

10.1101/2022.09.01.506183 — cancer biology — Posted on 2022-09-03

3895 Systematic Engineering of Virus-Like Particles to Identify Self-Assembly Rules for Shifting Particle Size

Ikwuagwu, B.; Hartman, E.; Mills, C.; Tullman-Ercek, D.

10.1101/2022.08.31.506130 — bioengineering — Posted on 2022-09-03

3896 Revisiting the burden borne by fumarase: enzymatic hydration of an olefin

Bellur, A.; Das, S.; Jayaraman, V.; Behera, S.; Suryavanshi, A.; Balasubramanian, S.; Balaram, P.; Jindal, G.; Balaram, H.

10.1101/2022.09.03.506457 — biochemistry — Posted on 2022-09-03

3897 Structural insights into the formation of repulsive Netrin guidance complexes

Priest, J. M.; Nichols, E. L.; Mendoza, J. L.; Shen, K.; Özkan, E.

10.1101/2022.09.03.506478 — biochemistry — Posted on 2022-09-03

3898 Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase

Murayama, Y.; Ehara, H.; Goto, M.; Aoki, M.; Yokoyama, T.; Sekine, S.-i.

10.1101/2022.09.02.506315 — biochemistry — Posted on 2022-09-03

3899 Neighbourhood effect of weeds on wheat root endospheric mycobiota

Hu, J.; Ricono, C.; Fournier, P.; Mondy, S.; Vandenkoornhuyse, P.; Mony, C.

10.1101/2022.09.02.506399 — ecology — Posted on 2022-09-03

3900 A Minimum Perturbation Theory of Deep Perceptual Learning

Shan, H.; Sompolinsky, H.

10.1101/2021.10.05.463260 — neuroscience — Posted on 2022-09-03

3901 High resolution photocatalytic mapping of SARS-CoV-2 Spike protein-host cell membrane interactions

Datta, S.; Tavares, A. H.; Reyes-Robles, T.; Ryu, K. A.; Khan, N.; Bechtel, T. J.; Bertoch, J. M.; White, C. H.; Hazuda, D. J.; Vora, K. A.; Hett, E. C.; Fadeyi, O. O.; Oslund, R. C.; Saeed, M.; Emili, A.

10.1101/2022.09.02.506438 — biochemistry — Posted on 2022-09-03

3902 The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins

Miller, A. N.; Houlihan, P. R.; Matamala, E.; Cabezas-Bratesco, D.; Lee, G. Y.; Cristofori-Armstrong, B.; Dilan, T. L.; Sanchez-Martinez, S.; Matthies, D.; Yan, R.; Yu, Z.; Ren, D.; Brauchi, S. E.; Clapham, D. E.

10.1101/2022.09.02.506428 — biophysics — Posted on 2022-09-03

3903 Plant production of high affinity nanobodies that block SARS-CoV-2 spike protein binding with its receptor, human angiotensin converting enzyme

Pitino, M.; Fleites, L. A.; Shrum, L.; Heck, M.; Shatters, R. G.

10.1101/2022.09.03.506425 — bioengineering — Posted on 2022-09-03

3904 The psychotomimetic ketamine disrupts the transfer of late sensory information in the corticothalamic network

Qin, Y.; Mahdavi, A.; Bertschy, M.; Anderson, P. M.; Kulikova, S.; Pinault, D.

10.1101/2022.02.21.476564 — neuroscience — Posted on 2022-09-03

3905 Plasticity in Na+/K+-ATPase thermal kinetics drives variation in the critical thermal minimum of adult Drosophila melanogaster

Andersen, M. K.; Robertson, R. M.; MacMillan, H. A.

10.1101/2022.08.31.506053 — physiology — Posted on 2022-09-03

3906 Modelling human endurance: Power laws vs critical power

Drake, J.; Finke, A.; Ferguson, R.

10.1101/2022.08.31.506028 — physiology — Posted on 2022-09-03

3907 Salinomycin disturbs Golgi apparatus function and specifically affects cells in epithelial-to-mesenchymal transition

Marjanovic, M.; Drazic, A.-M. M.; Mioc, M.; Klicek, F.; Novokmet, M.; Lauc, G.; Kralj, M.

10.1101/2022.08.31.506024 — cancer biology — Posted on 2022-09-03

3908 More than a ligand: PD-L1 promotes oncolytic virus infection via a metabolic shift that inhibits the type I interferon pathway.

Hodgins, J.; Abou-Hamad, J.; Hagerman, A.; Yakubovich, E.; Tanese De Souza, C.; Marotel, M.; Buchler, A.; Fadel, S.; Park, M.; Fong-McMaster, C.; Crupi, M. J. F.; Bell, J. C.; Harper, M.-E.; Rotstein, B.; Auer, R.; Vanderhyden, B.; Sabourin, L.; Bourgeois-Daigneault, M.-C.; Cook, D.; Ardolino, M.

10.1101/2022.08.31.506095 — cancer biology — Posted on 2022-09-03

3909 Artificial Intelligence based Liver Portal Tract Region Identification and Quantification with Transplant Biopsy Whole-Slide Images

Yu, H.; Sharifai, N.; Jiang, K.; Wang, F.; Teodoro, G.; Farris, A. B.; Kong, J.

10.1101/2022.08.31.506101 — bioinformatics — Posted on 2022-09-03

3910 Statistical inference of the rates of cell proliferation and phenotypic switching in cancer

Gunnarsson, E. B.; Foo, J.; Leder, K.

10.1101/2022.08.31.505619 — bioinformatics — Posted on 2022-09-03

3911 From sequence to function through structure: deep learning for protein design

Ferruz, N.; Heinzinger, M.; Akdel, M.; Goncearenco, A.; Naef, L.; Dallago, C.

10.1101/2022.08.31.505981 — bioinformatics — Posted on 2022-09-03

3912 Drug-Drug Interaction Extraction from Biomedical Text using Relation BioBERT with BLSTM

KafiKang, M.; Hendawi, A.

10.1101/2022.08.31.506076 — bioinformatics — Posted on 2022-09-03

3913 On quality thresholds for the clustering ofmolecular structures

Daura, X.; Conchillo-Sole, O.

10.1101/2022.08.31.505983 — bioinformatics — Posted on 2022-09-03

3914 A Bioinformatics Analysis Reveals that the Transcription Levels of Cell Surface Receptor Encoding Genes are Associated with the Drug Response of Breast Cancer Cells and the Drug Off-Target Effects

Sinkala, M.; Naran, K.; Madheswaran, S.; Ramamurthy, D.; Mungra, N.; Martin, D.; Barth, S.

10.1101/2022.08.31.506005 — bioinformatics — Posted on 2022-09-03

3915 openNAU: An open-source platform for normalizing, analyzing, and visualizing untargeted metabolomics data

Sun, Q.; Xu, Q.; Wang, M.; Wang, Y.; Zhang, D.; Lai, M.

10.1101/2022.08.31.506116 — bioinformatics — Posted on 2022-09-03

3916 Rapid Identity and Quantity CQA Test for Multivalent mRNA Drug Product Formulations

Gao, R. Y.; Riley, C. M.; Toth, E.; Blair, R. H.; Gerold, M. N.; McCormick, C.; Taylor, A. W.; Hu, T.; Rowlen, K. L.; Dawson, E. D.

10.1101/2022.08.31.506088 — bioengineering — Posted on 2022-09-03

3917 Classification Of Mushroom Using Artificial Neural Network

Gupta, A. P.

10.1101/2022.08.31.505980 — bioengineering — Posted on 2022-09-03

3918 Associations of Minor Histocompatibility Antigens with Clinical Outcomes Following Allogeneic Hematopoietic Cell Transplantation

Jadi, O.; Tang, H.; Olsen, K.; Vensko, S.; Zhu, Q.; Wang, Y.; Haiman, C. A.; Pooler, L.; Sheng, X.; Brock, G.; Webb, A.; Pasquini, M. C.; McCarthy, P. L.; Spellman, S. R.; Hahn, T.; Vincent, B. G.; Armistead, P.; Sucheston-Campbell, L. E.

10.1101/2022.08.31.506092 — genetics — Posted on 2022-09-03

3919 CIRKO: A chemical-induced reversible gene knockout system for studying gene function in situ

Shi, H.; Jin, Q.; Chen, F.; Ouyang, Z.; Gou, S.; Liu, X.; Li, L.; Mu, S.; Lai, C.; Zhang, Q.; Ye, Y.; Wang, K.; Lai, L.

10.1101/2022.08.31.506064 — genetics — Posted on 2022-09-03

3920 Consequences of life-cycle complexity to the potential for evolutionary branching

Vasconcelos, P.; Saltini, M.; Rueffler, C.

10.1101/2022.08.31.506002 — evolutionary biology — Posted on 2022-09-03

3921 Accumulated metagenomic studies reveal recent migration, whole genome evolution, and taxonomic incompleteness of orthomyxoviruses

Dudas, G.; Batson, J.

10.1101/2022.08.31.505987 — evolutionary biology — Posted on 2022-09-03

3922 Community-driven shark monitoring for informed decision making: A case study from Fiji

Ward-Paige, C. A.; Sykes, H.; Osgood, G.; Brunnschweiler, J.

10.1101/2022.08.31.505463 — ecology — Posted on 2022-09-03

3923 Decoding spatiotemporal gene expression of the developing human spinal cord and implications for ependymoma origin

Li, X.; Andrusivova, Z.; Czarnewski, P.; Langseth, C. M.; Andersson, A.; Liu, Y.; Gyllborg, D.; Braun, E.; Larsson, L.; Hu, L.; Alekseenko, Z.; Lee, H.; Avenel, C.; Kallner, H. K.; Akesson, E.; Adameyko, I.; Nilsson, M.; Linnarsson, S.; Lundeberg, J.; Sundstrom, E.

10.1101/2022.08.31.505986 — developmental biology — Posted on 2022-09-03

3924 Organoid-based single-cell spatiotemporal gene expression landscape of human embryonic development and hematopoiesis

Chao, Y.; Xiang, Y.; Xiao, J.; Zhang, S.; Zheng, W.; Wan, X.; LI, Z.; Gao, M.; Wang, G.; Chen, Z.; Ebrahimkhani, M.; Yang, C.; Wu, A. R.; Liu, P.; Huang, Y.; Sugimura, R.

10.1101/2022.09.02.505700 — developmental biology — Posted on 2022-09-03

3925 In Toto imaging of early Enteric Nervous System Development reveals that gut colonization is tied to proliferation downstream of Ret

Baker, P. A.; Ibarra-Garcia-Padilla, R.; Venkatesh, A.; Singleton, E. W.; Uribe, R. A.

10.1101/2022.08.31.506106 — developmental biology — Posted on 2022-09-03

3926 Purine nucleosides interfere with c-di-AMP levels and act as adjuvants to re-sensitize MRSA to β-lactam antibiotics

Nolan, A.; Zeden, M. S.; Campbell, C.; Kviatkovski, I.; Urwin, L.; Corrigan, R. M.; Gründling, A.; O'Gara, J. P.

10.1101/2022.09.01.506298 — microbiology — Posted on 2022-09-03

3927 Re-expression of CA1 and entorhinal activity patterns preserves temporal context memory at long timescales

Zou, F.; Guo, W.; Allen, E. J.; Wu, Y.; Charest, I.; Naselaris, T.; Kay, K.; Kuhl, B. A.; Hutchinson, J. B.; DuBrow, S.

10.1101/2022.08.31.506090 — neuroscience — Posted on 2022-09-03

3928 Magnetic Resonance Spectroscopy Spectral Registration Using Deep Learning

Ma, D. J.; Yang, Y.; Harguindeguy, N.; Tian, Y.; Guo, J.

10.1101/2022.08.31.506120 — neuroscience — Posted on 2022-09-03

3929 Associations between thinner retinal neuronal layers and suboptimal brain structural integrity: Are the eyes a window to the brain?

Barrett-Young, A.; Abraham, W. C.; Cheung, C. Y.; Gale, J.; Hogan, S.; Ireland, D.; Keenan, R.; Knodt, A. R.; Melzer, T. R.; Moffitt, T. E.; Ramrakha, S.; Tham, Y. C.; Wilson, G. A.; Wong, T. Y.; Hariri, A. R.; Poulton, R.

10.1101/2022.08.31.506114 — neuroscience — Posted on 2022-09-03

3930 CRF Neurons Establish Resilience via Stress-History-Dependent BNST Modulation

Haynes, S. E.; Seo, H. S.; Lacagnina, A.; Morel, C.; Afzal, M. F.; Menigoz, A.; Clem, R.; Rajan, K.; Mayberg, H.; Young, L.; Han, M.-H.

10.1101/2022.08.31.505596 — neuroscience — Posted on 2022-09-03

3931 Lifespan differences in visual short-term memory load-modulated functional connectivity

Lugtmeijer, S.; Geerligs, L.; Tsvetanov, K. A.; Mitchell, D. J.; Campbell, K. L.

10.1101/2022.08.31.506084 — neuroscience — Posted on 2022-09-03

3932 Toward a generalizable deep CNN for neural drive estimation across muscles and participants

Wen, Y.; Kim, S. J.; Avrillon, S.; Levine, J.; Hug, F.; Pons, J.

10.1101/2022.08.31.505855 — neuroscience — Posted on 2022-09-03

3933 Excitation creates a distributed pattern of cortical suppression due to varied recurrent input

O'Rawe, J. F.; Zhou, Z.; Li, A. J.; LaFosse, P. K.; Goldbach, H. C.; Histed, M. H.

10.1101/2022.08.31.505844 — neuroscience — Posted on 2022-09-03

3934 Biologic that disrupts PDE11A4 homodimerization in hippocampus CA1 reverses age-related proteinopathies in PDE11A4 and cognitive decline of social memories

Pilarzyk, K.; Capell, W.; Rips-Goodwin, A.; Porcher, L.; Kelly, M.

10.1101/2022.08.31.506102 — neuroscience — Posted on 2022-09-03

3935 Age and musical training effects on auditory short-term, long-term, and working memory

Rubio, G. F.; Olsen, E. R.; Klarlund, M.; Mallon, O.; Carlomagno, F.; Vuust, P.; Kringelbach, M. L.; Brattico, E.; Bonetti, L.

10.1101/2022.08.31.506048 — neuroscience — Posted on 2022-09-03

3936 Therapeutic Potential of Blocking GAPDH Nitrosylation with CGP3466b in Experimental Autoimmune Encephalomyelitis

Godfrey, W. H.; Hwang, S.; Gharibani, P.; Abramson, E.; Kornberg, M. D.

10.1101/2022.08.31.505712 — neuroscience — Posted on 2022-09-03

3937 Pten regulates endocytic trafficking of cell adhesion and signaling molecules to pattern the retina

Touahri, Y.; Hanna, J.; Tachibana, N.; David, L. A.; Olender, T.; Okawa, S.; Chinchalongporn, V.; Balakrishnan, A.; Cantrup, R.; Dixit, R.; Mattar, P.; Saleh, F.; Ilnytskyy, Y.; Murshed, M.; Mains, P.; Kovalchuk, I.; Lefebvre, J.; Cayouette, M.; del Sol, A.; Brand, M.; Reese, B. E.; Schuurmans, C.

10.1101/2022.08.31.506085 — neuroscience — Posted on 2022-09-03

3938 A model-free approach to link neural activity to behavioral tasks

Costabile, J. D.; Balakrishnan, K. A.; Schwinn, S.; Haesemeyer, M.

10.1101/2022.08.31.506108 — neuroscience — Posted on 2022-09-03

3939 The Entorhinal-DG/CA3 Pathway in the Medial Temporal Lobe Retains Visual Working Memory of a Simple Surface Feature

Xie, W.; Cappiello, M.; Yassa, M. A.; Ester, E.; Zaghloul, K.; Zhang, W.

10.1101/2022.08.31.506098 — neuroscience — Posted on 2022-09-03

3940 A genome-scale atlas reveals complex interplay of transcription and translation in an archaeon

Lorenzetti, A. P. R.; Kusebauch, U.; Zaramela, L. S.; Wu, W.-J.; de Almeida, J. P. P.; Turkarslan, S.; de Lomana, A. L. G.; Gomes-Filho, J. V.; Vencio, R. Z. N.; Moritz, R. L.; Koide, T.; Baliga, N. S.

10.1101/2022.08.31.505529 — systems biology — Posted on 2022-09-03

3941 Multivariable Graphical User Interface for Simulation of Tethered Particle Motion

Ramdin, K.; Hackl, M.; Chundawat, S. P. S.

10.1101/2022.08.31.506066 — scientific communication and education — Posted on 2022-09-03

3942 Membrane Retrieval after Immediately Releasable Pool (IRP) Exocytosis is produced by Dynamin-Dependent and Dynamin-Independent Mechanisms

Bayones, L.; Montenegro, M.; Diaz, J. M.; Bueno, S. A.; Gallo, L. I.; Marengo, F. D.

10.1101/2022.08.31.506099 — physiology — Posted on 2022-09-03

3943 Gain-of-function dynamin-2 mutations linked to centronuclear myopathy impair Ca2+-induced exocytosis in human myoblasts

Bayones, L.; Fernandez, M. J. G.; Hinostroza, F.; Matus, X. B.; Navarrete, J. V.; Gallo, L. I.; Parra, S.; Martinez, A. D.; Jamett, A. G.; Marengo, F. D.; Cardenas, A. M.

10.1101/2022.08.31.506089 — physiology — Posted on 2022-09-03

3944 Lysyl oxidase-dependent subendothelial matrix stiffening promotes RAGE-mediated retinal endothelial activation in diabetes

Chandrakumar, S.; Santiago Tierno, I.; Agarwal, M.; Matisioudis, N.; Kern, T. S.; Ghosh, K.

10.1101/2022.08.31.505952 — pathology — Posted on 2022-09-03

3945 Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer

Hany, D.; Zoetemelk, M.; Bhattacharya, K.; Nowak-Sliwinska, P.; Picard, D.

10.1101/2022.08.30.505871 — cancer biology — Posted on 2022-09-03

3946 Enhancer Reprogramming in Melanoma Immune Checkpoint Therapy Resistance

Maitituoheti, M.; Shi, A.; Tang, M.; Ho, L.-L.; Terranova, C.; Galani, K.; Keung, E.; Creasy, C.; Wu, M.; Chen, J.; Chen, N.; Singh, A.; Chaudhri, A.; Anvar, N.; Tarantino, G.; Yang, J.; Sarkar, S.; Jiang, S.; Malke, J.; Hayudu, L.; Burton, E.; Davies, M.; Gershenwald, J.; Hwu, P.; Lazar, A.; Cheah, J.; Soule, C.; Levine, S.; Bernatchez, C.; Saladi, S.; Liu, D.; Wargo, J.; Boland, G.; Kellis, M.; Rai, K.

10.1101/2022.08.31.506051 — cancer biology — Posted on 2022-09-03

3947 STAT3 cooperates with the core transcriptional regulatory circuitry to drive MYC expression and oncogenesis in anaplastic large cell lymphoma

Prutsch, N.; He, S.; Berezovskaya, A.; Durbin, A. D.; Dharia, N. V.; Stegmaier, K.; Matthews, J. D.; Hare, L.; Turner, S. D.; Kenner, L.; Merkel, O.; Young, R. A.; Abraham, B. J.; Look, A. T.; Zimmerman, M. W.

10.1101/2022.08.31.506044 — cancer biology — Posted on 2022-09-03

3948 Activity-dependent glassy cell mechanics : Mechanical properties measured with active microrheology

Umeda, K.; Nishizawa, K.; Ngao, W.; Miyamoto, T.; Ebata, H.; Mizuno, D.

10.1101/2022.09.02.506288 — biophysics — Posted on 2022-09-03

3949 Modeling the biomechanics of cells on microcarriers in a stirred-tank bioreactor An ABM-CFD coupling approach

Camphuijsen, J.; Cantarero Rivera, F. J.; Potter, G.; Clark, C.; Chen, J.; Kahan, S.; Aguilar, B.

10.1101/2022.08.31.505282 — bioinformatics — Posted on 2022-09-03

3950 KineticMSI, an R-based framework for relative quantification of spatial isotopic incorporation in mass spectrometry imaging experiments

Farzana, F.; Seidel, F. M.; Hannan, A.; Hatters, D.; Boughton, B.

10.1101/2022.08.31.505954 — bioinformatics — Posted on 2022-09-03

3951 OPUS-Fold3: a gradient-based protein all-atom folding and docking framework on TensorFlow

Xu, G.; Zhang, Y.; Wang, Q.; Ma, J.

10.1101/2022.08.31.506128 — bioinformatics — Posted on 2022-09-03

3952 A circulating biomarker of facioscapulohumeral muscular dystrophy clinical severity, valid in skeletal muscle and blood

Banerji, C. R. S.; Grecco, A.; Joosten, L. A.; van Engelen, B.; Zammit, P. S.

10.1101/2022.08.31.506017 — bioinformatics — Posted on 2022-09-03

3953 Refining Embedding-Based Binding Predictions by Leveraging AlphaFold2 Structures

Endres, L.; Olenyi, T.; Erckert, K. Y.; Weissenow, K.; Rost, B.; Littmann, M.

10.1101/2022.08.31.505997 — bioinformatics — Posted on 2022-09-03

3954 A two-compartment system for subfreezing temperatures preservation of large volumes of organic matter in an isochoric system

Nastase, G.; Botea, F.; Beschea, G. A.; Campean, S. I.; Barcu, A.; Popescu, I.; Rubinsky, B.; Serban, A.

10.1101/2022.08.31.506083 — bioengineering — Posted on 2022-09-03

3955 A Camera-Assisted Pathology Microscope to Capture the Lost Data in Clinical Glass Slide Diagnosis

Ashman, K.; Cooper, M. S.; Zhuge, H.; Fox, S. E.; Epstein, J. I.; Wenk, C.; Summa, B.; Brown, J. Q.

10.1101/2022.08.31.506042 — bioengineering — Posted on 2022-09-03

3956 Violation of rationality in shoaling decision making in zebrafish (Danio rerio)

Singh, A.; Kumari, K.; Rajaraman, B. K.

10.1101/2022.08.31.506011 — animal behavior and cognition — Posted on 2022-09-03

3957 Human blood vessel organoids reveal a critical role for CTGF in maintaining microvascular integrity

Romeo, S. G.; Secco, I.; Schneider, E.; Reumiller, C. M.; Santos, C. X.; Pooni, A.; Yin, X.; Theofilatos, K.; Cellone Trevelin, S.; Zeng, L.; Mann, G. E.; Margariti, A.; Mayr, M.; Shah, A. M.; Giacca, M.; Zampetaki, A.

10.1101/2022.09.01.505804 — cell biology — Posted on 2022-09-03

3958 MAM-STAT3-induced upregulation of mitochondrial Ca+2 causes immunosenescence in patients with type A mandibuloacral dysplasia

Padhiar, A. A.; Yang, X.; Li, Z.; Liao, J.; Ali, I.; Shu, W.; Chishti, A. A.; He, L.; Alam, G.; Faqeer, A.; Zhou, Y.; Zhang, S.; Wang, T.; Liu, T.; Zhou, M.; Wang, G.; Zou, X.; Zhou, G.

10.1101/2022.08.31.504639 — cell biology — Posted on 2022-09-03

3959 Transcriptional changes in human palate and skin healing

Leonardo, T. R.; Chen, L.; Schrementi, M. E.; Shi, J.; Marucha, P. T.; Glass, K.; DiPietro, L. A.

10.1101/2022.09.01.506279 — cell biology — Posted on 2022-09-03

3960 Hsp90 provides a platform for kinase dephosphorylation by PP5

Jaime-Garza, M.; Nowotny, C. A.; Coutandin, D.; Wang, F.; Tabios, M.; Agard, D. A.

10.1101/2022.09.02.506407 — biophysics — Posted on 2022-09-03

3961 FDA-Approved Drug Screening in Patient-Derived Organoids Demonstrates Potential of Drug Repurposing for Rare Cystic Fibrosis Genotypes

de Poel, E.; Spelier, S.; Hagemeijer, M. C.; van Mourik, P.; Suen, S. W. F.; Vonk, A. M.; Brunsveld, J. E.; Ithakisiou, G. N.; Kruisselbrink, E.; Oppelaar, H.; Berkers, G.; de Winter-de Groot, K. M.; Heida-Michel, S.; Jans, S. R.; van Panhuis, H.; Bakker, M.; van der Meer, R.; Roukema, J.; Dompeling, E.; Weersink, E. J. M.; Koppelman, G. H.; Blaazer, A. R.; van Muijlwijk - Koezen, J. E.; van der Ent, C. K.; Beekman, J. M.

10.1101/2022.09.02.506304 — molecular biology — Posted on 2022-09-03

3962 A cryogenic, coincident fluorescence, electron and ion beam microscope

Boltje, D.; Hoogenboom, J.; Jakobi, A. J.; Jensen, G. J.; Jonker, C.; Kaag, M.; Koster, A. J.; Last, M.; de Agrela Pinto, C.; Plitzko, J. M.; Raunser, S.; Tacke, S.; Wang, Z.; van der Wee, E.; Wepf, R.; den Hoedt, S.

10.1101/2022.09.02.506334 — molecular biology — Posted on 2022-09-03

3963 Purine nucleosides interfere with c-di-AMP levels and act as adjuvants to re-sensitize MRSA to β-lactam antibiotics

Nolan, A.; Zeden, M. S.; Campbell, C.; Kviatkovski, I.; Urwin, L.; Corrigan, R. M.; Gründling, A.; O'Gara, J. P.

10.1101/2022.09.01.506298 — microbiology — Posted on 2022-09-03

3964 Cell-intrinsic ceramides determine T cell function during melanoma progression

Hose, M.; Günther, A.; Naser, E.; Schumacher, F.; Schönberger, T.; Falkenstein, J.; Papadamakis, A.; Kleuser, B.; Becker, K. A.; Gulbins, E.; Haimovitz-Friedman, A.; Buer, J.; Westendorf, A.; Hansen, W.

10.1101/2022.08.31.505996 — immunology — Posted on 2022-09-03

3965 The mitochondrial ferredoxin-like is essential for the formation of complex I-containing respiratory supercomplexes in Arabidopsis thaliana

Röhricht, H.; Przybyla-Toscano, J.; Forner, J.; Boussardon, C.; Rouhier, N.; Keech, O.; Meyer, E. H.

10.1101/2022.09.02.506396 — plant biology — Posted on 2022-09-03

3966 Conjugation of bisphosphonates with scorpion venom enhanced apoptotic activities in pancreatic cancer cells

Alhakamy, N. A.; Al-Rabia, M. W.; Rizg, W. Y.; Alghaith, A. F.; Ahmed, O. A. A.; Fahmy, U. A.

10.1101/2022.08.30.505790 — pharmacology and toxicology — Posted on 2022-09-03

3967 Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer

Hany, D.; Zoetemelk, M.; Bhattacharya, K.; Nowak-Sliwinska, P.; Picard, D.

10.1101/2022.08.30.505871 — cancer biology — Posted on 2022-09-03

3968 CRISPR-Analytics (CRISPR-A): a platform for precise analytics and simulations for gene editing

Sanvicente, M.; Garcia-Valiente, A.; Jouide, S.; Jaraba-Wallace, J.; Bautista, E.; Escobosa, M.; Sanchez-Mejias, A.; Güell, M.

10.1101/2022.09.02.506351 — bioinformatics — Posted on 2022-09-03

3969 Alpha kinase 3 signaling at the M-band maintains sarcomere integrity and proteostasis in striated muscle.

McNamara, J. W.; Parker, B. L.; Voges, H. K.; Mehdiabadi, N. R. R.; Bolk, F.; Chung, D. D.; Charitakis, N.; Molendijk, J.; Lal, S.; Ramialison, M.; Karavendzas, K.; Pointer, H. L.; Syrris, P.; Lopes, L. R.; Perry, E. M.; Lynch, G. S.; Mills, R. J.; Hudson, J. E.; Watt, K. I.; Porrello, E. R.; Elliott, D. A.

10.1101/2022.09.01.506029 — cell biology — Posted on 2022-09-03

3970 A TetR-like transcriptional regulator in Stenotrophomonas maltophilia involved in fatty acid metabolism is controlled by quorum sensing signals

Coves, X.; Huedo, P.; Bravo, M.; Conchillo-Sole, O.; Gomez, A.-C.; Esteve-Codina, A.; Dabad, M.; Gut, M.; Daura, X.; Yero, D.; Gibert, I.

10.1101/2022.08.31.506136 — microbiology — Posted on 2022-09-03

3971 Assessing the coupling between local neural activity and global connectivity fluctuations: Application to human intracranial EEG during a cognitive task

Vila-Vidal, M.; Khawaja, M.; Carreno, M.; Roldan, P.; Rumia, J.; Donaire, A.; Deco, G.; Tauste Campo, A.

10.1101/2021.06.25.449912 — neuroscience — Posted on 2022-09-03

3972 Prosocial behavior in adult mice is sex-dependent

Misiolek, K.; Klimczak, M.; Chroszcz, M.; Szumiec, L.; Bryksa, A.; Przyborowicz, K.; Rodriguez Parkitna, J.; Harda, Z.

10.1101/2022.08.19.504492 — animal behavior and cognition — Posted on 2022-09-03

3973 Protein synthesis inhibition and loss of homeostatic functions in astrocytes from an Alzheimer's disease mouse model: a role for ER-mitochondria interaction.

Tapella, L.; Dematteis, G.; Moro, M.; Pistolato, B.; Tonelli, E.; Vanella, V. V.; Giustina, D.; La Forgia, A.; Restelli, E.; Barberis, E.; Villani, S.; Del Grosso, E.; Grilli, M.; Manfredi, M.; Corazzari, M.; Grolla, A. A.; Genazzani, A. A.; Lim, D.

10.1101/2022.03.24.485644 — neuroscience — Posted on 2022-09-03

3974 Astrocytes regulate inhibition in Fragile X Syndrome

Rais, M.; Kulinich, A. O.; Wagner, V.; Woodard, W.; Shuai, X. S.; Suley, S. N.; Kokash, J.; Piepponen, T. P.; Castren, M.; Razak, K.; Ethell, I.

10.1101/2022.02.08.479618 — neuroscience — Posted on 2022-09-03

3975 Sex biases in cancer and autoimmune disease incidence are strongly positively correlated with mitochondrial gene expression across human tissues

Crawford, D. R.; Sinha, S.; Nair, N. U.; Ryan, B. M.; Barnholtz-Sloan, J. S.; Mount, S. M.; Erez, A.; Aldape, K.; Castle, P. E.; Rajagopal, P. S.; Day, C.-P.; Schäffer, A. A.; Ruppin, E.

10.1101/2021.09.07.459207 — cancer biology — Posted on 2022-09-03

3976 Tri-dimensional Mitochondria Reconstructions of Cardiac Muscle Changes in Size Across Aging due to the MICOS Complex

Vue, Z.; Neikirk, K.; Vang, L.; Garza Lopez, E.; Christensen, T. A.; Shao, J.; Lam, J.; Beasley, H.; Marshall, A.; Crabtree, A.; Anudokem, J.; Rodriguez, B.; Kirk, B.; Bacevac, S.; Barongan, T.; Shao, B.; Evans, C.; Taylor, B.; Reddy, A. K.; Murray, S. A.; Mobley, B. C.; Gomez, J. A.; Phillips, M.; Exil, V.; Dai, D.-F.; Hinton, A.

10.1101/2022.04.23.489291 — biophysics — Posted on 2022-09-03

3977 ANKRD26 is a new regulator of type I cytokine receptor signaling in normal and pathological hematopoiesis

Raslova, H.; Basso-Valentina, F.; Donada, A.; Manchev, V. T.; Lisetto, M.; Balayn, N.; Martin, J.-E.; Muller, D.; Marin Oyarzun, C. P.; Duparc, H.; Arkoun, B.; Cumin, A.; Droin, N.; Faivre, L.; Biunno, I.; Balduini, A.; Debili, N.; Antony-Debre, I.; Marty, C.; Vainchenker, W.; Plo, I.; Favier, R.

10.1101/2022.09.01.506160 — cell biology — Posted on 2022-09-03

3978 Wide Window Acquisition and AI-based data analysis to reach deep proteome coverage for a wide sample range, including single cell proteomic inputs

Mayer, R. L.; Matzinger, M.; Schmücker, A.; Stejskal, K.; Krssakova, G.; Berger, F.; Mechtler, K.

10.1101/2022.09.01.506203 — biochemistry — Posted on 2022-09-02

3979 Global mapping of RNA-chromatin contacts reveals a proximity-dominated connectivity model for ncRNA-gene interactions

Limouse, C.; Smith, O. K.; Jukam, D.; Fryer, K.; Greenleaf, W. J.; Straight, A. F.

10.1101/2022.09.02.506418 — genomics — Posted on 2022-09-02

3980 NF-κB Decoy ODN-Loaded Poly lactic-co-glycolic Acid Nanospheres Inhibit Alveolar Ridge Resorption

Huang, A. C. S.; Ishida, Y.; Li, K.; Rintanalert, D.; Hatano-sato, K.; Oishi, S.; Hosomichi, J.; Usumi-Fujita, R.; Yamaguchi, H.; Tsujimoto, H.; Sasai, A.; Ochi, A.; Watanabe, H.; Ono, T.

10.1101/2022.08.30.505814 — immunology — Posted on 2022-09-02

3981 Ventral temporal and posteromedial sulcal morphology in autism spectrum disorder

Benitez, J. A. R.; Kannan, S.; Hastings, W.; Parker, B.; Willbrand, E.; Weiner, K. S.

10.1101/2022.09.01.506213 — neuroscience — Posted on 2022-09-02

3982 Conceptual associations generate sensory predictions

Yan, C.; de Lange, F. P.; Richter, D.

10.1101/2022.09.02.506283 — neuroscience — Posted on 2022-09-02

3983 The spatiotemporal dynamics of semantic integration in the human brain

Murphy, E.; Forseth, K. J.; Donos, C.; Rollo, P. S.; Tandon, N.

10.1101/2022.09.02.506386 — neuroscience — Posted on 2022-09-02

3984 Developmental shift in testosterone influence on prefrontal emotion control

Tyborowska, A.; Volman, I.; Niermann, H. C. M.; Dapprich, A. L.; Smeekens, S.; Cillessen, A. H. N.; Toni, I.; Roelofs, K.

10.1101/2022.09.02.505577 — neuroscience — Posted on 2022-09-02

3985 Hippocampal-cortical functional connectivity during memory encoding and retrieval

Raud, L.; Sneve, M. H.; Vidal-Pineiro, D.; Sorensen, O.; Folvik, L.; Ness, H. T.; Mowinckel, A. M.; Grydeland, H.; Walhovd, K. B.; Fjell, A. M.

10.1101/2022.09.02.506311 — neuroscience — Posted on 2022-09-02

3986 A recurrent neural network model of prefrontal brain activity during a working memory task

Piwek, E. P.; Stokes, M. G.; Summerfield, C. P.

10.1101/2022.09.02.506349 — neuroscience — Posted on 2022-09-02

3987 Now What Sequence? Pre-trained Ensembles for Bayesian Optimization of Protein Sequences

Yang, Z.; Milas, K. A.; White, A. D.

10.1101/2022.08.05.502972 — bioinformatics — Posted on 2022-09-02

3988 Enhanced intramyocardial vascular progenitor cell delivery promotes post-myocardial infarction healing by polarizing pro-regenerative neutrophils

Hong, X.; Luo, A. C.; Doulamis, I.; Oh, N.; del Nido, P. J.; Martin, J. M. M.; Lin, R.-Z.

10.1101/2022.06.30.497378 — bioengineering — Posted on 2022-09-02

3989 Fluorescent peptomer substrates for differential degradation by metalloproteases

Austin, M. J.; Schunk, H. C.; Watkins, C. M.; Ling, N. R.; Chauvin, J. M.; Morton, L. D.; Rosales, A. M.

10.1101/2022.08.31.506126 — biochemistry — Posted on 2022-09-02

3990 Structural Basis for pre-tRNA Recognition and Processing by the Human tRNA Splicing Endonuclease Complex

Hayne, C. K.; Butay, K. J. U.; Stewart, Z. D.; Krahn, J. M.; Perera, L.; Williams, J. G.; Petrovitch, R. M.; Deterding, L. J.; Matera, G.; Borgnia, M. J.; Stanley, R. E.

10.1101/2022.09.02.506201 — biochemistry — Posted on 2022-09-02

3991 Population structure and evolution of Salmonella enterica serotype Typhi in Zimbabwe before a typhoid conjugate vaccine immunization campaign

Thilliez, G.; Mashe, T.; Chaibva, B. V.; Robertson, V.; Bawn, M.; Tarupiwa, A.; Takawira, F. T.; Kock, M. M.; Midzi, S.; Mwamakamba, L. W.; Matheu, J.; Kingsley, R. A.; Ehlers, M. M.

10.1101/2022.09.01.506167 — genomics — Posted on 2022-09-02

3992 Global profiling of the RNA and protein complexes of Escherichia coli by size exclusion chromatography followed by RNA sequencing and mass spectrometry (SEC-seq)

Chihara, K.; Gerovac, M.; Hör, J.; Vogel, J.

10.1101/2022.09.02.506378 — molecular biology — Posted on 2022-09-02

3993 Disentangling marine microbial networks across space

Deutschmann, I. M.; Delage, E.; Giner, C. R.; Sebastian, M.; Poulain, J.; Aristegui, J.; Duarte, C. M.; Acinas, S. G.; Massana, R.; Gasol, J. M.; Eveillard, D.; Chaffron, S.; Logares, R.

10.1101/2021.07.12.451729 — microbiology — Posted on 2022-09-02

3994 ATRAP - Accurate T cell Receptor Antigen Pairing through data-driven filtering of sequencing information from single-cells

Povlsen, H. R.; Bentzen, A. K.; Kadivar, M.; Jessen, L. E.; Hadrup, S. R.; Nielsen, M.

10.1101/2022.08.31.506001 — immunology — Posted on 2022-09-02

3995 MHC-II expressing neutrophils circulate in blood and milk during mastitis and show high microbicidal activity

Rambault, M.; Gilbert, F. B.; Roussel, P.; Tessier, A.; David, V.; Germon, P.; Winter, N.; Remot, A.

10.1101/2022.09.01.506187 — immunology — Posted on 2022-09-02

3996 Texture coding in higher order somatosensory cortices of primates

Long, K. H.; Greenspon, C. M.; van Driesche, A.; Lieber, J. D.; Bensmaia, S. J.

10.1101/2022.08.19.504511 — neuroscience — Posted on 2022-09-02

3997 Growing DAGs: Optimization Functions for Pathway Reconstruction Algorithms

Köse, T. B.; Li, J.; Ritz, A.

10.1101/2022.07.27.501737 — systems biology — Posted on 2022-09-02

3998 Attenuation of polysialic acid biosynthesis in cells by the small molecule inhibitor 8-keto-sialic acid

Hunter, C.; Gao, Z.; Chen, H.-M.; Thompson, N.; Wakarchuk, W.; nitz, m.; Withers, S.; Willis, L. M.

10.1101/2022.09.02.506362 — biochemistry — Posted on 2022-09-02

3999 Pro-inflammatory chemokines CCL5, CXCL12, and CX3CL1 bind to and activate platelet integrin αIIbβ3 in an allosteric manner.

Takada, Y. K.; Fujita, M.; takada, y.

10.1101/2022.09.01.506262 — biochemistry — Posted on 2022-09-02

4000 20E-dependent tyrosine phosphorylation of phospholipase C gamma underpins egg development in the malaria vector Anopheles gambiae

Ferracchiato, S.; Catteruccia, F.; Peirce, M. J.

10.1101/2022.09.01.506175 — biochemistry — Posted on 2022-09-02

4001 Differential scanning fluorimetry as a measure of functionality of refolded anti-malarial antibody fragments

Valiyaparambil, A.; Jagannath, D. K.; Viswanath, V. K.; Kumar, N.; Shukla, J. P.; Pradhan, S.; Lakshminarasimhan, A.

10.1101/2022.09.01.504486 — biochemistry — Posted on 2022-09-02

4002 Copper as a Novel Regulator of PERK

Bond, S. E.; Beratan, N. R.; Bond, M. K.; Brady, D. C.; Jordan-Sciutto, K. L.

10.1101/2022.09.02.506340 — biochemistry — Posted on 2022-09-02

4003 Hyperaerated metalation calculator for E. coli strain JM109 (DE3) grown in LB media

Clough, S. E.; Osman, D.; Young, T. R.; Robinson, N. J.

10.1101/2022.09.02.506343 — biochemistry — Posted on 2022-09-02

4004 Derivation of a minimal functional XIST by combining human and mouse interaction domains

Brown, C. J.; Navarro Cobos, M. J.; Baldry, S. E. L.; Morales Guzman, S. I.

10.1101/2022.09.02.506429 — genetics — Posted on 2022-09-02

4005 Record-matching of STR profiles with fragmentary genomic SNP data

Kim, J.; Rosenberg, N. A.

10.1101/2022.09.01.505545 — genetics — Posted on 2022-09-02

4006 CRTC-1 Balances Histone Trimethylation and Acetylation to Promote Longevity

Silva-Garcia, C. G.; Lascarez-Lagunas, L. I.; Heintz, C.; Papsdorf, K.; Pajuelo, L.; Sharma, A.; Colaiacovo, M. P.; Brunet, A.; Mair, W. B.

10.1101/2022.08.31.506037 — genetics — Posted on 2022-09-02

4007 A role for BCL2L13 and autophagy in germline purifying selection of mtDNA

Kremer, L. S.; Bozhilova, L. V.; Rubalcava-Gracia, D.; Filograna, R.; Upadhyay, M.; Koolmeister, C.; Chinnery, P. F.; Larsson, N.-G.

10.1101/2022.09.02.506367 — genetics — Posted on 2022-09-02

4008 Intracellular pH dynamics regulates intestinal stem cell lineage specification

Liu, Y.; Reyes, E.; Castillo-Azofeifa, D.; Klein, O. D.; Barber, D. L.; Nystul, T.

10.1101/2021.10.28.466337 — developmental biology — Posted on 2022-09-02

4009 Distinguishing Signal from Noise: Understanding Patterns of Non-Detections to Inform Accurate Quantitative Metabarcoding

Gold, Z.; Shelton, A. O.; Casendino, H. R.; Duprey, J.; Gallego, R.; Van Cise, A.; Fisher, M.; Jensen, A. J.; D'Agnese, E.; Andruszkiewicz Allan, E.; Ramon-Laca, A.; Garber-Yonts, M.; Labare, M.; Parsons, K. M.; Kelly, R. P.

10.1101/2022.09.02.506420 — molecular biology — Posted on 2022-09-02

4010 Elongation of Very Long Chain Fatty Acids Like- 3 (Elovl3) is activated by ZHX2 and is a regulator of cell cycle progression

Creasy, K. T.; Ren, H.; Jiang, J.; Peterson, M. L.; Spear, B. T.

10.1101/2022.09.02.506374 — molecular biology — Posted on 2022-09-02

4011 Environmental feedback drives oxidative stress response heterogeneity in bacterial populations

Choudhary, D.; Lagage, V.; Foster, K.; Uphoff, S.

10.1101/2022.09.02.506373 — microbiology — Posted on 2022-09-02

4012 Chitosan-coated carboxylic acids show antimicrobial activity against antibiotic-resistant Gram-negative and positive pathogens

Best, E.; James-Meyer, L.; Cogan, T.

10.1101/2022.09.02.506354 — microbiology — Posted on 2022-09-02

4013 Machine learning identification of Pseudomonas aeruginosa strains from colony image data

Rattray, J. B.; Walden, R.; Marquez Zacarias, P.; Molotkova, E.; Perron, G.; Solis-Lemus, C.; Pimentel-Alarcon, D.; Brown, S. P.

10.1101/2022.09.02.506375 — microbiology — Posted on 2022-09-02

4014 Immuno-targeting of Gram-positive Pathogens via a Cell Wall Binding Tick Antifreeze Protein

Dalesandro, B.; Pires, M.

10.1101/2022.09.02.506389 — microbiology — Posted on 2022-09-02

4015 Parity modulates impact of BMI and Gestational Weight Gain on gut microbiota in human pregnancy

Kennedy, K.; Plagemann, A.; Sommer, J.; Hofmann, M.; Henrich, W.; Barrett, J. F. R.; Surette, M. G.; Atkinson, S.; Braun, T.; Sloboda, D. M.

10.1101/2022.09.02.506244 — microbiology — Posted on 2022-09-02

4016 Diversity and ecology of Caudoviricetes phages with genome terminal repeats in fecal metagenomes from four Dutch cohorts

Gulyaeva, A.; Garmaeva, S.; Kurilshikov, A.; Vich Vila, A.; Riksen, N. P.; Netea, M. G.; Weersma, R. K.; Fu, J.; Zhernakova, A.

10.1101/2022.09.02.506393 — microbiology — Posted on 2022-09-02

4017 Constitutive expression and distinct properties of IFN-epsilon protect the female reproductive tract from Zika virus infection

Coldbeck-Shackley, R.; Romeo, O.; Rosli, S.; Gearing, L. J.; Gould, J. A.; Lim, S. S.; Van der Hoek, K.; Eyre, N. S.; Shue, B.; Robertson, S. A.; Best, S. M.; Tate, M. D.; Hertzog, P.; Beard, M. R.

10.1101/2022.09.01.505971 — immunology — Posted on 2022-09-02

4018 Dectin-1 Stimulation Promotes a Distinct Inflammatory Signature in the Setting of HIV-infection and Aging

Kumar, A.; Wang, J.; Zhou, H.; Radcliffe, C.; Vander Wyk, B.; Allore, H.; Tsang, S.; Barakat, L.; Mohanty, S.; Zhao, H.-y.; Shaw, A.; Zapata, H.

10.1101/2022.09.01.505710 — immunology — Posted on 2022-09-02

4019 Transcriptional and clonal characterization of cytotoxic CD8+ T cells in crescentic glomerulonephritis

Zhao, Y.; Mueller, A.; Cicek, H.; Paust, H.-J.; Sivayoganathan, A.; Linke, A.; Wegscheid, C.; Wiech, T.; Huber, T. B.; Meyer-Schwesinger, C.; Bonn, S.; Panzer, U. P.; Tiegs, G.; Krebs, C. F.; Neumann, K.

10.1101/2022.08.31.506004 — immunology — Posted on 2022-09-02

4020 Hippocampal and medial prefrontal cortices encode structural task representations following progressive and interleaved training schedules

Berens, S. C.; Bird, C. M.

10.1101/2021.08.11.455977 — neuroscience — Posted on 2022-09-02

4021 Polymer brush bilayers at thermal equilibrium: A density functional theory approach

Edwards, M. J.

10.1101/316141 — biophysics — Posted on 2022-09-02

4022 Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets

Morin, A. M.; Chu, E. C.-P.; Sharma, A.; Adrian-Hamazaki, A.; Pavlidis, P.

10.1101/2022.08.30.505909 — bioinformatics — Posted on 2022-09-02

4023 Improved Genome Editing by an Engineered CRISPR-Cas12a

Ma, E.; Chen, K.; Shi, H.; Stahl, E. C.; Adler, B. A.; Liu, J.; Zhou, K.; Ye, J.; Doudna, J. A.

10.1101/2022.09.02.506401 — biochemistry — Posted on 2022-09-02

4024 A new strategy for identifying polysialylated proteins reveals they are secreted from cancer cells as soluble proteins and as part of extracellular vesicles

Hunter, C.; Derksen, T.; Karathra, J.; Baker, K.; Nitz, M.; Willis, L. M.

10.1101/2022.09.01.506237 — biochemistry — Posted on 2022-09-02

4025 A thousand-genome panel retraces the global spread and climatic adaptation of a major crop pathogen

Feurtey, A.; Lorrain, C.; McDonald, M. C.; Milgate, A.; Solomon, P.; Warren, R.; Puccetti, G.; Scalliet, G.; Torriani, S.; Gout, L.; Marcel, T.; Suffert, F.; Alassimone, J.; Lipzen, A.; Yoshinaga, Y.; Daum, C.; Barry, K.; Grigoriev, I. V.; Goodwin, S. B.; Genissel, A.; Seidl, M. F.; Stukenbrock, E. H.; Lebrun, M.-H.; Kema, G. H. J.; McDonald, B. A.; Croll, D.

10.1101/2022.08.26.505378 — genomics — Posted on 2022-09-02

4026 Targeted insertion of reporter transgene into a gene safe harbor in human blood fluke, Schistosoma mansoni

10.1101/2022.09.02.506379 — molecular biology — Posted on 2022-09-02

4027 VSGs expressed during natural T. b. gambiense infection exhibit extensive sequence divergence and a subspecies-specific expression bias

So, J.; Sudlow, S.; Sayeed, A.; Grudda, T.; Deborggraeve, S.; Ngoyi, D. M.; Desamber, D. K.; Wickstead, B.; Lejon, V.; Mugnier, M. R.

10.1101/2021.09.09.459620 — microbiology — Posted on 2022-09-02

4028 Comparative genomic and metagenomic investigations of the Corynebacterium tuberculostearicum species complex reveals potential mechanisms underlying associations to skin health and disease

Salamzade, R.; Swaney, M. H.; Kalan, L.

10.1101/2022.08.31.506047 — microbiology — Posted on 2022-09-02

4029 The hidden diversity of ancient bornaviral sequences from X and P genes in vertebrate genomes

Garcia, B. C. B.; Mukai, Y.; Tomonaga, K.; Horie, M.

10.1101/2022.05.06.490909 — microbiology — Posted on 2022-09-02

4030 Cell type specific IL-27p28 (IL-30) deletion uncovers an unexpected regulatory function of IL-30 in autoimmune inflammation

Kim, D.; Kim, S.; Kang, M.-s.; Yin, Z.; Min, B.

10.1101/2022.01.03.474823 — immunology — Posted on 2022-09-02

4031 Information encoded in volumes and areas of dendritic spines is nearly maximal across mammalian brains

Karbowski, J.; Urban, P.

10.1101/2021.12.30.474505 — neuroscience — Posted on 2022-09-02

4032 Subject-specific whole-brain parcellations of nodes and boundaries are modulated differently under 10Hz rTMS

Belov, V.; Kozyrev, V.; Singh, A.; Sacchet, M. D.; Goya-Maldonado, R.

10.1101/2021.03.09.434571 — neuroscience — Posted on 2022-09-02

4033 3D Visualisation of trans-syncytial nanopores provides a pathway for paracellular diffusion across the human placental syncytiotrophoblast

Lewis, R.; Baskaran, H.; Green, J.; Tashev, S.; Palaiologou, E.; Lofthouse, E. M.; Cleal, J. K.; Page, A.; Chatelet, D.; Goggin, P.; Sengers, B. G.

10.1101/2022.01.26.477815 — physiology — Posted on 2022-09-02

4034 Mammary Tissue-Derived Extracellular Matrix Hydrogels Reveal the Role of the Irradiated Microenvironment in Breast Cancer Recurrence

Zhu, T.; Alves, S. M.; Adamo, A.; Wen, X.; Corn, K. C.; Shostak, A.; Shaub, N. D.; Hacker, B. C.; D'Amore, A.; Bardhan, R.; Rafat, M.

10.1101/2022.05.16.492117 — cancer biology — Posted on 2022-09-02

4035 Novel eDNA approaches to monitor Western honey bee (Apis mellifera) microbial and arthropod communities

Boardman, L.; Marcelino, J. A.; Valentin, R.; Boncristiani, H.; Standley, J.; Ellis, J. D.

10.1101/2022.08.31.506105 — ecology — Posted on 2022-09-02

4036 Population Genetics and Analysis of Molecular Variance (AMOVA) of the Monkeypox virus interferon-alpha-beta receptor gene and its evolutionary relationship with the Orthopoxvirus genus

Felix, P. T.; Santos, A. C. d. S.; Nascimento, I. A. d.; Silva, L. S. d.

10.1101/2022.09.02.506281 — evolutionary biology — Posted on 2022-09-02

4037 Neutrophil extracellular traps have auto-catabolic activity and produce mononucleosome-associated circulating DNA

PISAREVA, E.; Mihalovicova, L.; Pastor, B.; Kudriavstev, A.; Mirandola, A.; Mazard, T.; Badiou, S.; Maus, U.; Ostermann, L.; Weinmann-Menke, J.; neuberger, E.; simon, P.; THIERRY, A.

10.1101/2022.09.01.506266 — molecular biology — Posted on 2022-09-02

4038 Novel monoclonal antibodies showing broad neutralizing activity for SARS-CoV-2 variants including Omicrons BA.5 and BA.2.75

Ishimaru, H.; Nishimura, M.; Tjan, L. H.; Sutandhio, S.; Marini, M. I.; Effendi, G. B.; Shigematsu, H.; Kato, K.; Hasegawa, N.; Aoki, K.; Kurahashi, Y.; Furukawa, K.; Shinohara, M.; Nakamura, T.; Arii, J.; Nagno, T.; Nakamura, S.; Sano, S.; Iwata, S.; Mori, Y.

10.1101/2022.09.02.506305 — microbiology — Posted on 2022-09-02

4039 White-tailed deer (Odocoileus virginianus) may serve as a wildlife reservoir for nearly extinct SARS-CoV-2 variants of concern

Caserta, L. C.; Martins, M.; Butt, S. L.; Hollingshead, N.; Covaleda, L. M.; Everts, M.; Schuler, K.; Diel, D. G.

10.1101/2022.09.02.506368 — microbiology — Posted on 2022-09-02

4040 SARS-CoV-2 nucleocapsid protein inhibits the stress response through RNA-binding domain N2b

Aloise, C.; Schipper, J. G.; Donselaar, T.; Hurdiss, D. L.; de Groot, R. J.; van Kuppeveld, F. J. M.

10.1101/2022.09.02.506332 — microbiology — Posted on 2022-09-02

4041 Growth hormone receptor (GHR) in AgRP neurons regulatesthermogenesis in aged mice in a sex-specific manner

Stilgenbauer, L.; de Lima, J. B. M.; Debarba, L. K.; Khan, M.; Koshko, L.; Kopchick, J. J.; Bartke, A.; Schneider, A.; Sadagurski, M.

10.1101/2022.08.31.506031 — neuroscience — Posted on 2022-09-02

4042 Metabolic costs of walking and arm reaching in persons with mild multiple sclerosis

Courter, R.; Alvarez, E.; Enoka, R.; Ahmed, A.

10.1101/2022.08.31.506034 — physiology — Posted on 2022-09-02

4043 The combination of morphogenic regulators BABY BOOM and GRF-GIF improves maize transformation efficiency

Chen, Z.; Debernardi, J. M.; Dubcovsky, J.; Gallavotti, A.

10.1101/2022.09.02.506370 — plant biology — Posted on 2022-09-02

4044 Local induction of IAA5 and IAA29 promotes DNA damage-triggered stem cell death in Arabidopsis roots

Takahashi, N.; Ogita, N.; Koike, T.; Nishimura, K.; Inagaki, S.; Umeda, M.

10.1101/2022.09.02.506394 — plant biology — Posted on 2022-09-02

4045 Photosystem II monomeric antenna CP26 has a key role in Non-Photochemical Quenching in Chlamydomonas reinhardtii

Cazzaniga, S.; Kim, M.; Pivato, M.; Perozeni, F.; Sardar, S.; D'Andrea, C.; Jin, E.; Ballottari, M.

10.1101/2022.09.01.506249 — plant biology — Posted on 2022-09-02

4046 Using "sentinel" plants to improve early detection of invasive plant pathogens

Lovell-Read, F. A.; Parnell, S. R.; Cunniffe, N. J.; Thompson, R. N.

10.1101/2022.09.01.506171 — plant biology — Posted on 2022-09-02

4047 Key role of auxin cellular accumulation in totipotency and pluripotency acquisition

Karami, O.; Khadem, A.; Rahimi, A.; Offringa, R.

10.1101/2022.09.02.505607 — plant biology — Posted on 2022-09-02

4048 Comparative phylotranscriptomics reveals a 110 million years-old symbiotic program

Libourel, C.; Keller, J.; Brichet, L.; Cazale, A.-C.; Carrere, S.; Vernie, T.; Couzigou, J.-M.; Callot, C.; Dufau, I.; Cauet, S.; Marande, W.; Bulach, T.; Suin, A.; Masson-Boivin, C.; Remigi, P.; Delaux, P.-M.; Capela, D.

10.1101/2022.09.02.505815 — plant biology — Posted on 2022-09-02

4049 In situ imaging across ecosystems to resolve the fine-scale oceanographic drivers of a globally significant planktonic grazer

Greer, A. T.; Schmid, M. S.; Duffy, P. I.; Robinson, K. L.; Genung, M. A.; Luo, J. Y.; Panaiotis, T.; Briseno-Avena, C.; Frischer, M. E.; Sponaugle, S.; Cowen, R. K.

10.1101/2022.08.31.506093 — ecology — Posted on 2022-09-02

4050 Habitat use differences mediate anthropogenic threat exposure in white sturgeon

Walter, J. A.; Singer, G. P.; Reuman, D. C.; Colborne, S. F.; Sheppard, L. W.; O'Donnell, D. R.; Coombs, N.; Johnston, M.; Miller, E. A.; Steel, A. E.; Kelly, J. T.; Fangue, N. A.; Rypel, A. L.

10.1101/2022.08.31.505999 — ecology — Posted on 2022-09-02

4051 Long-range alteration of the physical environment mediates cooperation between Pseudomonas aeruginosa swarming colonies

Deforet, M.

10.1101/2022.06.29.498166 — systems biology — Posted on 2022-09-02

4052 Glioblastoma disrupts cortical network activity at multiple spatial and temporal scales

Meyer, J.; Yu, K.; Deneen, B.; Noebels, J.

10.1101/2022.08.31.505988 — cancer biology — Posted on 2022-09-02

4053 Activation of ERK by altered RNA splicing in cancer

Zhang, Y.; Siraj, M. A.; Chakraborty, P.; Tseng, R.; Ku, L.-T.; Das, S.; Dey, A.; Dwivedi, S. K. D.; Rao, G.; Zhang, M.; Yang, D.; Hossen, M. N.; Ding, W.-Q.; Fung, K.-M.; Bhattacharya, R.; Escobar-Hoyos, L.; Mukherjee, P.

10.1101/2022.08.31.505957 — cancer biology — Posted on 2022-09-02

4054 Correlating viscosity and molecular crowding with fluorescent nanobeads and molecular probes: in vitro and in vivo

Lecinski, S.; Shepherd, J. W.; Bunting, K.; Dresser, L.; Quinn, S. D.; MacDonald, C.; Leake, M. C.

10.1101/2022.06.27.497768 — biophysics — Posted on 2022-09-02

4055 RedRibbon: A new rank-rank hypergeometric overlap pipeline to compare gene and transcript expression signatures

Piron, A.; Szymczak, F.; Alvelos, M. I.; Defrance, M.; Lenaerts, T.; Eizirik, D. L.; Cnop, M.

10.1101/2022.08.31.505818 — bioinformatics — Posted on 2022-09-02

4056 Succinate mediates inflammation-induced adrenocortical dysfunction

Mateska, I.; Witt, A.; Hagag, E.; Sinha, A.; Yilmaz, C.; Thanou, E.; Sun, N.; Kolliniati, O.; Patschin, M.; Abdelmegeed, H.; Henneicke, H.; Kanczkowski, W.; Wielockx, B.; Tsatsanis, C.; Dahl, A.; Walch, A.; Li, K. W.; Peitzsch, M.; Chavakis, T.; Alexaki, V. I.

10.1101/2022.04.29.490066 — immunology — Posted on 2022-09-02

4057 Neuronal C-Reactive Protein Mediates Neuropathic Pain by Activating Nociceptive FcγRI-Coupled Signaling

Liu, F.; Su, S.; Zhang, L.; Fang, Y.; Cui, H.; Sun, J.; Xie, Y.; Ma, C.

10.1101/2022.08.30.505953 — neuroscience — Posted on 2022-09-02

4058 EEG-based Graph Neural Network Classification of Alzheimer's Disease: An Empirical Evaluation of Functional Connectivity Methods

Klepl, D.; He, F.; Wu, M.; Blackburn, D. J.; Sarrigiannis, P. G.

10.1101/2022.06.14.496080 — neuroscience — Posted on 2022-09-02

4059 A clinical stage LMW-DS drug inhibits infection of human cells by Dengue, Zika and Yellow Fever viruses

Logan, A.; Mazzon, M.; Bruce, L.; Barnes, N. M.

10.1101/2022.08.31.503293 — immunology — Posted on 2022-09-02

4060 Exercise performance is not improved in mice with skeletal muscle deletion of natriuretic peptide clearance receptor

Jia, B.; Hasse, A.; Shi, F.; Collins, S.

10.1101/2022.08.30.505918 — physiology — Posted on 2022-09-02

4061 Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates

Nardella, F.; Dobrescu, I.; Hassan, H.; Rodrigues, F.; Thiberge, S.; Mancio, L.; Tafit, A.; Jallet, C.; Cadet-Daniel, V.; Goussin, S.; Lorthiois, A.; Menon, Y.; Molinier, N.; Pechalrieu, D.; Long, C.; Sautel, F.; Matondo, M.; Duchateau, M.; Medard, G.; Witkowski, B.; Scherf, A.; Halby, L.; Arimondo, P. B.

10.1101/2022.08.30.505923 — pathology — Posted on 2022-09-02

4062 Spatial analysis of the metastatic brain tumor immune and extracellular matrix microenvironment

Widodo, S. S.; Dinevska, M.; Cuzcano, L. R.; Papanicolaou, M.; Cox, T. R.; Stylli, S. S.; Mantamadiotis, T.

10.1101/2022.08.30.505945 — cancer biology — Posted on 2022-09-02

4063 A Comprehensive Enumeration of the Human Proteostasis Network. 1. Components of Translation, Protein Folding, and Organelle-Specific Systems

The Proteostasis Consortium, ; Elsasser, S.; Finley, D.; Mockler, E.; Lima, L.; Finkbeiner, S.; Gestwicki, J. E.; Stoeger, T. E.; Cao, K.; Garza, D.; Kelly, J. W.; Collier, M.; Rainbolt, T. K.; Taguwa, S.; Chou, C.-C.; Aviner, R.; Barbosa, N.; Moralez-Polanco, F.; Masto, V. B.; Frydman, J.; Elia, L. P.; Morimoto, R. I.; Powers, E. T.

10.1101/2022.08.30.505920 — bioinformatics — Posted on 2022-09-02

4064 Data augmentation for imbalanced blood cell image classification

Rana, P.; Sowmya, A.; Meijering, E.; Song, Y.

10.1101/2022.08.30.505762 — bioinformatics — Posted on 2022-09-02

4065 Brain-wide transcriptome-based metabolic alterations in Parkinsons disease: human inter-region and human-experimental model correlations

Odongo, R.; Bellur, O.; Abdik, E.; Cakir, T.

10.1101/2022.08.31.505965 — bioinformatics — Posted on 2022-09-02

4066 General cognitive performance declines with female age and is negatively related to fledging success in a wild bird

Soravia, C.; Ashton, B. J.; Thornton, A.; Ridley, A. R.

10.1101/2022.08.30.505947 — animal behavior and cognition — Posted on 2022-09-02

4067 Incidental Temporal Binding in Rats: A Novel Behavioral Task Relevant to Episodic Memory

Radostova, D.; Kuncicka, D.; Krajcovic, B.; Hejtmanek, L.; Petrasek, T.; Svoboda, J.; Stuchlik, A.; Brozka, H.

10.1101/2022.08.30.505895 — animal behavior and cognition — Posted on 2022-09-02

4068 ROBUST AND EFFICIENT ACTIVE GENETICS GENE CONVERSION IN THE RAT AND MOUSE

Lai, C.; Alvarez, O.; Read, K.; van Fossan, D.; Conner, C. M.; Xu, S. X.-R.; Cowley, D. O.; Gantz, V.; Webb, D. R.; Jarnagin, K.

10.1101/2022.08.30.505951 — genetics — Posted on 2022-09-02

4069 Coenzyme A governs proinflammatory macrophage metabolism

Timblin, G. A.; Tharp, K. M.; Hoeve, J. t.; Baydemir, I.; Khantwal, C.; Farahzad, J. N.; Dominguez-Andres, J.; Vance, R. E.; Weaver, V. M.

10.1101/2022.08.30.505732 — immunology — Posted on 2022-09-02

4070 ACAT1/SOAT1 Blockade Suppresses LPS-Mediated Neuroinflammation by Modulating the Fate of Toll-Like Receptor 4 in Microglia

Li, H.; Huynh, T. N.; Duong, M. T.; Gow, J.; Chang, C. C.; Chang, T. Y.

10.1101/2022.08.30.505911 — neuroscience — Posted on 2022-09-02

4071 Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines

Licht-Murava, A.; Meadows, S. M.; Palaguachi, F.; Song, S. C.; Bram, Y.; Zhou, C.; Jackvony, S.; Schwartz, R. E.; Froemke, R. C.; Orr, A. L.; Orr, A. G.

10.1101/2022.08.30.503668 — neuroscience — Posted on 2022-09-02

4072 Profound lipid dysregulation in mutant TDP-43 mice is ameliorated by the glucocerebrosidase 2 inhibitor ambroxol

Luikinga, S. J.; Henriques, A.; Ngo, S.; Rupasinghe, T.; Loeffler, J.-P.; Spedding, M.; Turner, B. J.

10.1101/2022.08.30.505901 — neuroscience — Posted on 2022-09-02

4073 Cinemeducation improves early clinical exposure to Inborn Errors of Metabolism

Dutta, A. K.; Oberoi, A.; Goswami, K.; Modi, J. N.; Goyal, P. K.; Samuel, S.; Mondal, T.; Sahoo, S.; Pal, A.

10.1101/2022.08.30.505958 — scientific communication and education — Posted on 2022-09-02

4074 GraMDTA: Multimodal Graph Neural Networks for Predicting Drug-Target Associations

Yella, J. K.; Ghandikota, S. K.; Jegga, A. G.

10.1101/2022.08.30.505168 — bioinformatics — Posted on 2022-09-02

4075 Characterizing the targets of transcription regulators by aggregating ChIP-seq and perturbation expression data sets

Morin, A. M.; Chu, E. C.-P.; Sharma, A.; Adrian-Hamazaki, A.; Pavlidis, P.

10.1101/2022.08.30.505909 — bioinformatics — Posted on 2022-09-02

4076 SHINE: Protein Language Model based Pathogenicity Prediction for Inframe Insertion and Deletion Variants

Fan, X.; Pan, H.; Tian, A.; Chung, W.; Shen, Y.

10.1101/2022.08.30.505840 — bioinformatics — Posted on 2022-09-02

4077 Assessing biological network dynamics: Comparing numerical simulations with analytical decomposition of parameter space

Hari, K.; Duncan, W.; Ibrahim, M. A.; Jolly, M. K.; Cummins, B.; Gedeon, T.

10.1101/2022.08.31.506131 — systems biology — Posted on 2022-09-02

4078 High-grade serous ovarian carcinoma organoids as models of chromosomal instability

Vias, M.; Morrill Gavarro, L.; Sauer, C. M.; Sanders, D.; Piskorz, A. M.; Couturier, D.-L.; Ballereau, S.; Hernando, B.; Hall, J.; Correia-Martins, F.; Markowetz, F.; Macintyre, G.; Brenton, J. D.

10.1101/2022.09.01.506155 — cancer biology — Posted on 2022-09-02

4079 Inferring protein fitness landscapes from laboratory evolution experiments

D'Costa, S.; Hinds, E. C.; Freschlin, C. R.; Song, H.; Romero, P. A.

10.1101/2022.09.01.506224 — bioinformatics — Posted on 2022-09-02

4080 Mathematical Modeling of Bottleneck Transmissions of RNA Virus Infecting a Homogeneous Host Population

Furuyama, T. N.; Janini, L. M. R.; Carvalho, I. M. V. G.; Antoneli, F. M.

10.1101/2022.08.30.505912 — evolutionary biology — Posted on 2022-09-02

4081 Integrating phylogenetics with intron positions illuminates the origin of the complex spliceosome

Vosseberg, J.; Stolker, D.; von der Dunk, S. H. A.; Snel, B.

10.1101/2022.08.31.505394 — evolutionary biology — Posted on 2022-09-02

4082 Host mixotrophy, habitat stability and recombination may all decrease geographic differentiation between symbiont populations in Western Pacific deep-sea mussels

Breusing, C.; Xiao, Y.; Russell, S.; Corbett-Detig, R.; Li, S.; Sun, J.; Chen, C.; Lan, Y.; Qian, P.-Y.; Beinart, R. A.

10.1101/2022.08.30.505939 — evolutionary biology — Posted on 2022-09-02

4083 Nicked tRNAs are stable reservoirs of tRNA halves in cells and biofluids

Costa, B.; Li Calzi, M.; Castellano, M.; Blanco, V.; Cuevasanta, E.; Litvan, I.; Ivanov, P.; Witwer, K.; Cayota, A.; Tosar, J. P.

10.1101/2022.08.31.506125 — molecular biology — Posted on 2022-09-02

4084 Environmental DNA phylogeography: successful reconstruction of phylogeographic patterns of multiple fish species from a cup of water

Tsuji, S.; Shibata, N.; Inui, R.; Nakao, R.; Akamatsu, Y.; Watanabe, K.

10.1101/2022.09.02.506317 — molecular biology — Posted on 2022-09-02

4085 Molecular Determinants for Differential Activation of the Vibrio parahaemolyticus Bile Acid Receptor

Zou, A.; Kinch, L. N.; Chimalapati, S.; Garcia Rodriguez, N.; Tomchick, D. R.; Orth, K.

10.1101/2022.09.02.506320 — microbiology — Posted on 2022-09-02

4086 Computational Modeling of the Chlamydial Developmental Cycle Reveals a Potential Role for Asymmetric Division

Cherelli, T. J.; Grieshaber, N.; Appa, C.; Grieshaber, S. S.

10.1101/2022.09.01.506140 — microbiology — Posted on 2022-09-02

4087 Synthetic genotype networks

Santos-Moreno, J.; Tasiudi, E.; Kusumawardhani, H.; Stelling, J.; Schaerli, Y.

10.1101/2022.09.01.506159 — synthetic biology — Posted on 2022-09-02

4088 Microfluidic immuno-serology assay revealed a limited diversity of protection against COVID-19 in patients with altered immunity

Kim, D.; Biancon, G.; Bai, Z.; VanOudenhove, J.; Liu, Y.; Kothari, S.; Gowda, L.; Kwan, J. M.; Buitrago-Pocasangre, N. C.; Lele, N.; Asashima, H.; Racke, M. K.; Wilson, J. E.; Givens, T. S.; Tomayko, M. M.; Schulz, W. L.; Longbrake, E. E.; Hafler, D. A.; Halene, S.; Fan, R.

10.1101/2022.08.31.506117 — bioengineering — Posted on 2022-09-02

4089 A MAD7-based genome editing system for E. coli

Mund, M.; Weber, W.; Degreif, D.; Schiklenk, C.

10.1101/2022.09.01.505100 — bioengineering — Posted on 2022-09-02

4090 When two is a crowd - Structural mapping of PEAK pseudokinase interactions identifies 14 3 3 as a molecular switch for PEAK3/Crk signaling.

Roy, M. J.; Surudoi, M. G.; Kropp, A.; Hou, J.; Dai, W.; Hardy, J. M.; Liang, L.-Y.; Cotton, T. R.; Lechenberg, B. C.; Dite, T. A.; Ma, X.; Daly, R. J.; Patel, O.; Lucet, I.

10.1101/2022.09.01.506260 — biochemistry — Posted on 2022-09-02

4091 An RNA sequence that reprograms ribosomes to bypass a 50 nucleotide coding gap is encoded by a mobile element whose sequence conservation illuminates its bypass mechanisms

Manning, G.; Atkins, J. F.

10.1101/2022.08.31.505936 — biochemistry — Posted on 2022-09-02

4092 Testing the effect of oxytocin on social grooming in bonobos

Brooks, J.; Kano, F.; Yeow, H.; Morimura, N.; Yamamoto, S.

10.1101/2021.11.30.468796 — animal behavior and cognition — Posted on 2022-09-02

4093 Forward genetic screen of homeostatic antibody levels in the Collaborative Cross identifies MBD1 as a novel regulator of B cell homeostasis

Hampton, B. K.; Plante, K. S.; Whitmore, A. C.; Linnertz, C. L.; Madden, E. A.; Noll, K. E.; Boyson, S. P.; Parotti, B.; Bell, T. A.; Hock, P.; Shaw, G. D.; Pardo-Manuel de Villena, F.; Heise, M. T.; Ferris, M. T.

10.1101/2022.08.30.505889 — genetics — Posted on 2022-09-02

4094 Pulse-Width Modulation of Gene Expression in Budding Yeast

Machne, R.; Murray, D. B.; Bernhart, S. H.; Axmann, I. M.; Stadler, P. F.

10.1101/2021.05.26.444658 — cell biology — Posted on 2022-09-02

4095 IFITM3 blocks viral entry by sorting lipids and stabilizing hemifusion

Klein, S.; Golani, G.; Lolicato, F.; Beyer, D.; Herrmann, A.; Wachsmuth-Melm, M.; Reddmann, N.; Brecht, R.; Lahr, C.; Hosseinzadeh, M.; Kolovou, A.; Schorb, M.; Schwab, Y.; Bruegger, B.; Nickel, W.; Schwarz, U. S.; Chlanda, P.

10.1101/2022.09.01.506185 — molecular biology — Posted on 2022-09-02

4096 Temperature causes species-specific responses to UV-induced DNA damage in amphibian larvae

Hird, C.; Franklin, C. E.; Cramp, R.

10.1101/2022.09.01.506274 — molecular biology — Posted on 2022-09-02

4097 The Tramtrack group BTB protein domains are Arthropoda-specific multimerization modules

Bonchuk, A.; Balagurov, K.; Boyko, K.; Sluchanko, N. N.; Khrustaleva, A.; Burtseva, A.; Kuzmina, N.; Arkova, O.; Khalisova, K.; Popov, V.; Georgiev, P.

10.1101/2022.09.01.506177 — molecular biology — Posted on 2022-09-02

4098 ONECUT2 restricts Microfold cell numbers in the small intestine; a multi-omics study

Velez, M. V. L.; Neikes, H. K.; Snabel, R. R.; Quint, Y.; Qian, C.; Martens, A.; Veenstra, G. J. C.; Freeman, M. R.; van Heeringen, S. J.; Vermeulen, M.

10.1101/2022.09.01.506202 — molecular biology — Posted on 2022-09-02

4099 Global characterization of gene expression in the brain of starved immature R. prolixus

Nevoa, J. C.; Estivalis, J. M. L.; Pais, F. S.-M.; Fernandes, G. R.; Lorenzo, M. G.; Guarneri, A. A.

10.1101/2022.09.01.506236 — molecular biology — Posted on 2022-09-02

4100 N-terminal acetylation shields proteins from degradation and promotes age-dependent motility and longevity

Varland, S.; Silva, R. D.; Kjosas, I.; Faustino, A.; Bogaert, A.; Billmann, M.; Boukhatmi, H.; Kellen, B.; Costanzo, M.; Drazic, A.; Osberg, C.; Chan, K.; Zhang, X.; Tong, A. H. Y.; Andreazza, S.; Lee, J. J.; Nedyalkova, L.; Usaj, M.; Whitworth, A. J.; Andrews, B. J.; Moffat, J.; Myers, C. L.; Gevaert, K.; Boone, C.; Martinho, R. G.; Arnesen, T.

10.1101/2022.09.01.505523 — molecular biology — Posted on 2022-09-02

4101 Hallucination of closed repeat proteins containing central pockets

An, L.; Hicks, D. R.; Zorine, D.; Dauparas, J.; Wicky, B. I. M.; Milles, L. F.; Courbet, A.; Bera, A. K.; Nguyen, H.; Kang, A.; Carter, L.; Baker, D.

10.1101/2022.09.01.506251 — molecular biology — Posted on 2022-09-02

4102 An Engineered T7 RNA Polymerase for efficient co-transcriptional capping with reduced dsRNA byproducts in mRNA synthesis

Miller, M.; Alvizo, O.; Chng, C.; Jenne, S.; Mayo, M.; Mukherjee, A.; Sundseth, S.; Chinthala, A.; Penfield, J.; Riggins, J.; Zhang, S.; Sero, A.; Dassie, J.; Leatherbury, N.; Baskerville, S.; Huisman, G.

10.1101/2022.09.01.506264 — molecular biology — Posted on 2022-09-02

4103 Prevalence and genetic characterisation of Giardia duodenalis in river water and riverbed sediment using next-generation sequencing

Murei, A.; Momba, M. N. B.

10.1101/2022.09.01.506148 — molecular biology — Posted on 2022-09-02

4104 A dueling-competent signal-sensing module guides precise delivery of cargo proteins into target cells by engineered Pseudomonas aeruginosa

Dong, T.; Wu, L.-L.; Yan, S.; Pei, T.-T.; Tang, M.-X.; Li, H.; Liang, X.; Sun, S.

10.1101/2022.09.02.506313 — microbiology — Posted on 2022-09-02

4105 Streamlined implementation of a machine learning model to classify screen relevant neoplasia using reference-based OTU clustering

Armour, C. R.; Sovacool, K. L.; Close, W. L.; Topcuoglu, B. D.; Wiens, J.; Schloss, P. D.

10.1101/2022.09.01.506299 — microbiology — Posted on 2022-09-02

4106 An Azobenzene G-quadruplex Ligand Exhibits Promising Antibacterial Activity against Escherichia coli

Ramos-Soriano, J.; Takebayashi, Y.; Samphire, J.; O'Hagan, M.; Gurr, C.; Heesom, K. J.; Lewis, P. A.; Spencer, J.; Galan, M. C.

10.1101/2022.09.01.506212 — microbiology — Posted on 2022-09-02

4107 The oxygen tolerant reductive glycine pathway in eukaryotes: a native methanol, formate and CO2 assimilation pathway in the yeast Komagataella phaffii

Mitic, B. M.; Troyer, C.; Hann, S.; Mattanovich, D.

10.1101/2022.09.01.506198 — microbiology — Posted on 2022-09-02

4108 Simultaneous adjunctive treatment of malaria and its co-evolved genetic disorder sickle cell anaemia

Safeukui, I.; Ware, R. E.; Narla, M.; Haldar, K.

10.1101/2022.09.01.506230 — microbiology — Posted on 2022-09-02

4109 MiGut: a scalable in vitro platform for simulating the human gut microbiome - development, validation, and simulation of antibiotic induced dysbiosis

Davis Birch, W.; Moura, I.; Ewin, D.; Wilcox, M.; Buckley, A.; Culmer, P.; Kapur, N.

10.1101/2022.09.02.506309 — microbiology — Posted on 2022-09-02

4110 P1 bacteriophage-enabled delivery of CRISPR-Cas9 antimicrobial activity against Shigella flexneri

Huan, Y. W.; Torraca, V.; Brown, R.; Fa-arun, J.; Miles, S. L.; Oyarzun, D. A.; Mostowy, S.; Wang, B.

10.1101/2022.09.02.506314 — microbiology — Posted on 2022-09-02

4111 Phagocytosis via complement receptor 3 enables microbes to evade killing by neutrophils

Smirnov, A.; Daily, K. P.; Gray, M. C.; Ragland, S. A.; Werner, L. M.; Johnson, M. B.; Eby, J. C.; Hewlett, E. L.; Taylor, R. P.; Criss, A. K.

10.1101/2022.09.01.506228 — microbiology — Posted on 2022-09-02

4112 Volatile aroma compound production is affected by growth rate in S. cerevisiae

Visinoni, F.; Zhang, P.; Hollywood, K.; Carlin, S.; Vrhovsek, U.; Winterburn, J.; Delneri, D.

10.1101/2022.09.01.506294 — microbiology — Posted on 2022-09-02

4113 Natural recombination among Type I restriction-modification systems creates diverse genomic methylation patterns among Xylella fastidiosa strains

O'Leary, M. L.; Burbank, L. P.

10.1101/2022.09.01.506293 — microbiology — Posted on 2022-09-02

4114 Mucosal and systemic neutralizing antibodies to norovirus and rotavirus by oral immunization with recombinant rotavirus in infant mice

Kawagishi, T.; Sanchez-Tacuba, L.; Feng, N.; Costantini, V. P.; Tan, M.; Jiang, X.; Green, K. Y.; Vinje, J.; Ding, S.; Greenberg, H. B.

10.1101/2022.09.01.505917 — microbiology — Posted on 2022-09-02

4115 Variable effects on virulence of bacteriophage resistance mechanisms in extraintestinal pathogenic Escherichia coli

Gaborieau, B.; Delattre, R.; Adiba, S.; Clermont, O.; Denamur, E.; Ricard, J.-D.; Debarbieux, L.

10.1101/2022.09.01.506217 — microbiology — Posted on 2022-09-02

4116 Phenotypic Assessment of Clinical Escherichia coli Isolates Predicts Uropathogenic Potential

Shea, A.; Frick-Cheng, A. E.; Smith, S. N.; Mobley, H. L. T.

10.1101/2022.08.31.506135 — microbiology — Posted on 2022-09-02

4117 Interactions between culturable bacteria are highly non-additive

Baichman-Kass, A.; Song, T.; Friedman, J.

10.1101/2022.09.01.506178 — microbiology — Posted on 2022-09-02

4118 Comparison of Culture Results between Specimens from Corneal Scraping with Microhomogenization and Corneal Swab in Moderate and Severe Bacterial Corneal Ulcers

Martha, F.; Edwar, L.; Karuniawati, A.; Fuady, A.; Tuasikal, R. M.

10.1101/2022.09.01.506297 — microbiology — Posted on 2022-09-02

4119 ZEB2 regulates the development of CD11c+ atypical B cells

Gao, X.; Shen, Q.; Roco, J. A.; Frith, K.; Munier, C. M. L.; Nekrasov, M.; Dalton, B.; He, J.-S.; Jaeger, R.; Cook, M. C.; Zaunders, J. J.; Cockburn, I. A.

10.1101/2022.09.01.506173 — immunology — Posted on 2022-09-02

4120 Reliability of decision-making and reinforcement learning computational parameters

Mkrtchian, A.; Valton, V.; Roiser, J. P.

10.1101/2021.06.30.450026 — neuroscience — Posted on 2022-09-02

4121 Phylogenomics reveals the evolutionary origin of lichenization in chlorophyte algae

Puginier, C.; Libourel, C.; Otte, J.; Skaloud, P.; Haon, M.; Grisel, S.; Petersen, M.; Berrin, J.-G.; Delaux, P.-M.; Dal Grande, F.; Keller, J.

10.1101/2022.01.06.475074 — plant biology — Posted on 2022-09-02

4122 CRISPR Mediated Transactivation in the Human Disease Vector Aedes aegypti

Bui, M.; Benetta, E. D.; Dong, Y.; Zhao, Y.; Yang, T.; Li, M.; Antoshechkin, I. A.; Buchman, A.; Bottino-Rojas, V.; James, A. A.; Perry, M. W.; Dimopoulos, G.; Akbari, O.

10.1101/2022.08.31.505972 — bioengineering — Posted on 2022-09-02

4123 Opposite regulation of glycogen metabolism by cAMP produced in the cytosol and at the plasma membrane

Verhoeven, A. J.; Bizerra, P. F. V.; Gilglioni, E. H.; Go, S.; Li, H. L.; Elferink, R. P. J. O.; Chang, J.-C.

10.1101/2022.09.01.505928 — biochemistry — Posted on 2022-09-02

4124 Lipid Desaturation Regulates the Balance between Self-renewal and Differentiation in Mouse Blastocyst-derived Stem Cells

Thomas, C.; Haimson, R. B.; Zacharia, A.; Orih, P.; Shehadeh, A.; Saidemberg, D.; Kogan, N. M.; Alfandary, S.; Serruya, R.; Dagan, A.; Petit, I.; Moussaieff, A.

10.1101/2022.07.28.501839 — developmental biology — Posted on 2022-09-02

4125 Melaninization Reduces Cryptococcus neoformans Susceptibility to Mechanical Stress

Mattoon, E. R.; Cordero, R. J.; Casadevall, A.

10.1101/2022.09.01.506291 — microbiology — Posted on 2022-09-02

4126 Natural and pathological aging distinctively impact the vomeronasal system and social behavior

Portales, A.; Chamero, P.; Jurado, S.

10.1101/2022.08.31.505522 — neuroscience — Posted on 2022-09-02

4127 An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

Brisevac, D.; Peralta, C. M.; Kaiser, T. S.

10.1101/2022.08.30.505825 — evolutionary biology — Posted on 2022-09-02

4128 Adaptive, maladaptive, neutral, or absent plasticity: Hidden caveats of reaction norms

Eriksson, M.; Kinnby, A.; De Wit, P.; Rafajlovic, M.

10.1101/2022.06.21.497038 — evolutionary biology — Posted on 2022-09-02

4129 Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover.

Simons, D.; Attfield, L. A.; Jones, K. E.; Watson-Jones, D.; Kock, R.

10.1101/2022.08.30.505792 — ecology — Posted on 2022-09-02

4130 Planarian dorsoventral Netrins organize a muscle midline signaling center and regulate blastema formation

Schad, E. G.; Petersen, C. P.

10.1101/2022.08.31.506052 — developmental biology — Posted on 2022-09-02

4131 LGR5 targeting molecules as therapeutic agents for multiple cancer types

Chen, H.-C.; Mueller, N.; Stott, K.; Rivers, E.; Kapeni, C.; Sauer, C. M.; Beke, F.; Walsh, S.; Ashman, N.; O'Brien, L. M.; Fard, A. R.; Godsinia, A.; Joud, F.; Giger, O.; Zlobec, I.; Olan, I.; Aitken, S. J.; Hoare, M.; Mair, R.; Serrao, E.; Brenton, J. D.; Garcia-Gimenez, A.; Richardson, S. E.; Huntly, B.; Spring, D. R.; Skjodt, M.-O.; Skjodt, K.; de la Roche, M.; de la Roche, M.

10.1101/2022.09.01.506182 — cell biology — Posted on 2022-09-02

4132 MMD scaffolds ACSL4 and MBOAT7 to promote polyunsaturated phospholipid synthesis and susceptibility to ferroptosis

Phadnis, V. V.; Snider, J.; Wong, V.; Vaccaro, K. D.; Kunchok, T.; Allen, J.; Yao, Z.; Geng, B.; Weiskopf, K.; Stagljar, I.; Henry, W. S.; Weinberg, R. A.

10.1101/2022.09.01.506096 — cell biology — Posted on 2022-09-02

4133 Preventing Jacob-induced transcriptional inactivation of CREB protects synapses from β-amyloid in Alzheimer's Disease

Grochowska, K. M.; Gomes, G. M.; Raman, R.; Kaushik, R.; Sosulina, L.; Kaneko, H.; Oelschlegel, A. M.; Yuanxiang, P.; Reyes-Resina, I.; Bayraktar, G.; Samer, S.; Spilker, C.; Woo, M. S.; Morawski, M.; Goldschmidt, J.; Friese, M. A.; Rossner, S.; Navarro Brugal, G.; Remy, S.; Reissner, C.; Karpova, A.; Kreutz, M. R.

10.1101/2020.01.08.898304 — neuroscience — Posted on 2022-09-02

4134 Bounded rational decision-making models suggest capacity-limited concurrent motor planning in human posterior parietal and frontal cortex

Schach, S.; Lindner, A.; Braun, D. A.

10.1101/2021.07.13.452019 — neuroscience — Posted on 2022-09-02

4135 PIP2 and Ca2+ regulation of TMEM16A currents in excised inside-out patches

Tembo, M.; Lara-Santos, C.; Rosenbaum, J. C.; Carlson, A. E.

10.1101/2022.08.30.505925 — physiology — Posted on 2022-09-02

4136 Temperature-dependent Thermodynamic and Photophysical Properties of SYTO-13 Dye Bound to DNA

DeJaco, R. F.; Majikes, J. M.; Liddle, J. A.; Kearsley, A. J.

10.1101/2022.08.31.505902 — biophysics — Posted on 2022-09-02

4137 Structural insights into regulation of the PEAK3 scaffold by 14-3-3

Torosyan, H.; Paul, M. D.; Forget, A.; Lo, M.; Diwanji, D.; Pawlowski, K.; Krogan, N. J.; Jura, N.; Verba, K. A.

10.1101/2022.09.01.506268 — biophysics — Posted on 2022-09-02

4138 Solid-State Single-Molecule Sensing with the Electronic Life-detection Instrument for Enceladus/Europa (ELIE)

Carr, C. E.; Ramirez-Colon, J. L.; Duzdevich, D. E.; Lee, S.; Taniguchi, M.; Ohshiro, T.; Komoto, Y.; Soderblom, J. M.; Zuber, M. T.

10.1101/2022.08.31.505913 — biophysics — Posted on 2022-09-02

4139 Markov State Modelling Reveals Heterogeneous Drug-Inhibition Mechanism of Calmodulin

Westerlund, A. M.; Sridhar, A.; Dahl, L.; Andersson, A.; Bodnar, A.-Y.; Delemotte, L.

10.1101/2022.06.08.495419 — biophysics — Posted on 2022-09-02

4140 Neurogenin 2 and Neuronal Differentiation 1 control proper development of the chick trigeminal ganglion and its nerve branches

Bina, P.; Taneyhill, L.

10.1101/2022.08.31.506039 — developmental biology — Posted on 2022-09-02

4141 Transcriptome profiling of tendon fibroblasts at the onset of embryonic muscle contraction reveals novel force-responsive genes

Nayak, P.; Subramanian, A.; Schilling, T. F.

10.1101/2022.08.31.506026 — developmental biology — Posted on 2022-09-02

4142 Nuclear-enriched protein phosphatase 4 ensures outer kinetochore assemblyprior to nuclear dissolution

Rocha, H.; Simoes, P. A.; Budrewicz, J.; Lara-Gonzalez, P.; Xavier de Carvalho, A.; Dumont, J.; Desai, A.; Gassmann, R.

10.1101/2022.09.01.505886 — cell biology — Posted on 2022-09-02

4143 Human cellular model systems of β-thalassemia enablein-depth analysis of disease phenotype

Daniels, D. E.; Ferrer-Vicens, I.; Hawksworth, J.; Andrienko, T. N.; Finnie, E. M.; Ferguson, D. C. J.; Oliveira, A. S. F.; Szeto, J.-Y. A.; Wilson, M. C.; Frayne, J.

10.1101/2022.09.01.506225 — cell biology — Posted on 2022-09-02

4144 Small, fat-filled lipid droplets remain spherical as they indent a nucleus, dilute the lamina, and cause rupture

Ivanovska, I.; Tobin, M.; Dooling, L.; Discher, D.

10.1101/2022.09.01.506190 — cell biology — Posted on 2022-09-02

4145 Dissecting aneuploidy phenotypes by constructing Sc2.0 chromosome VII and SCRaMbLEing synthetic disomic yeast

Shen, Y.; Gao, F.; Wang, Y.; Wang, Y.; Zheng, J.; Gong, J.; Zhang, J.; Luo, Z.-Q.; Schindler, D.; Deng, Y.; Ding, W.; Lin, T.; Swidah, R.; Zhao, H.; Jiang, S.; Chen, S.; Chen, T.; Wang, Y.; Luo, Y.; Mitchell, L. A.; Bader, J.; Zhang, G.; Shen, X.; Wang, J.; Fu, X.; Dai, J.; Boeke, J. D.; Yang, H. D.; Xu, X.; Cai, Y.

10.1101/2022.09.01.506252 — synthetic biology — Posted on 2022-09-02

4146 Extending Conway's Game of Life

Getz, W. M.; Salter, R. M.

10.1101/2022.08.30.505937 — scientific communication and education — Posted on 2022-09-02

4147 Cancer-Associated Mutations Enhance The Sensitivity Of The Trupath GαQ/11 System

Safitri, D.; Harris, M.; Pearce, A.; Huang, X.; Rosa, M.; Barkan, K.; Wills, E.; Marti-Solano, M.; Falk, M.; Ladds, G.

10.1101/2022.09.01.506210 — pharmacology and toxicology — Posted on 2022-09-02

4148 Conformational dynamics and putative substrate extrusion pathways of the N-glycosylated outer membrane factor CmeC from Campylobacter jejuni

Newman, K.; Khalid, S.

10.1101/2022.08.31.506067 — biophysics — Posted on 2022-09-02

4149 Physics-based inverse design of lipid packing defect sensing peptides; distinguishing sensors from binders

van Hilten, N.; Methorst, J.; Verwei, N.; Risselada, H. J.

10.1101/2022.09.01.506157 — biophysics — Posted on 2022-09-02

4150 Senescent cells enhance newt limb regeneration by promoting muscle dedifferentiation

Walters, H.; Troyanovskiy, K.; Yun, M. H.

10.1101/2022.09.01.506186 — developmental biology — Posted on 2022-09-02

4151 A neuroepithelial wave of BMP signalling drives anteroposterior specification of the tuberal hypothalamus

Placzek, M.; Chinnaiya, K.; Burbridge, S.; Jones, A.; Kim, D. W.; Place, E.; Manning, E.; Groves, I.; Sun, C.; Towers, M.; Blackshaw, S.

10.1101/2022.08.31.506043 — developmental biology — Posted on 2022-09-02

4152 Duplicated zebrafish (Danio rerio) inositol phosphatases inpp5ka and inpp5kb diverged in expression pattern and function

Shukla, D.; Gural, B. M.; Cauley, E. S.; Roberts, L. E.; Karas, B. F.; Cavallo, L.; Turkalj, L.; Moody, S. A.; Swan, L. E.; Manzini, M. C.

10.1101/2022.08.31.506059 — developmental biology — Posted on 2022-09-02

4153 Distinct features in fish Bouncer proteins determine sperm-egg compatibility

Gert, K. R. B.; Panser, K.; Surm, J. M.; Steinmetz, B.; Schleiffer, A.; Moran, Y.; Kondrashov, F.; Pauli, A.

10.1101/2022.09.01.506233 — developmental biology — Posted on 2022-09-02

4154 Specific sensory neurons and insulin-like peptides modulate food type-dependent oogenesis and fertilization in Caenorhabditis elegans

Mishra, S.; Marbach, K.; Dabaja, M.; Akhlaq, A.; Rovcanin, M.; Pereira, B.; Chandra, R.; Caballero, A.; de Abreu, D. F.; Ch'ng, Q.; Alcedo, J.

10.1101/2022.08.31.506073 — developmental biology — Posted on 2022-09-02

4155 Aneuploidy triggers autophagy and p53-mediated apoptosis and impairs second lineage segregation in human preimplantation embryos

Regin, M.; Lei, Y.; De Deckersberg, E. C.; Guns, Y.; Verdyck, P.; Verheyen, G.; Van de Velde, H.; Sermon, K.; Spits, C.

10.1101/2022.08.31.506009 — developmental biology — Posted on 2022-09-02

4156 The RhoGEF protein Plekhg5 regulates medioapical actomyosin dynamics of apical constriction during Xenopus gastrulation

Baldwin, A. T.; Popov, I. K.; Keller, R. T.; Wallingford, J. B.; Chang, C.

10.1101/2022.08.31.506049 — developmental biology — Posted on 2022-09-02

4157 Porcn is essential for growth and invagination of the mammalian optic cup

Fuhrmann, S.; Ramirez, S.; Abouda, M. M.; Campbell, C. D.

10.1101/2022.09.01.506058 — developmental biology — Posted on 2022-09-02

4158 Cellular senescence modulates progenitor cell expansion during axolotl limb regeneration

Yu, Q.; Walters, H.; Pasquini, G.; Singh, S. P.; Perinan, D. L.; Petzold, A.; Kesavan, P.; Subiran, C.; Suner, I. G.; Knapp, D.; Wagner, A.; Bernardos, A.; Alfonso, M.; Nadar, G.; Dahl, A.; Busskamp, V.; Manaez, R.; Yun, M.

10.1101/2022.09.01.506196 — developmental biology — Posted on 2022-09-02

4159 Zinc supplementation induced transcriptional changes in primary human retinal pigment epithelium: a single cell RNA sequencing study to understand age-related macular degeneration

Emri, E.; Cappa, O.; Kelly, C.; Kortvely, E.; SanGiovanni, J. P.; McKay, B.; Bergen, A. A.; Simpson, D. A.; Lengyel, I.

10.1101/2022.09.01.504514 — cell biology — Posted on 2022-09-02

4160 Multimodal Object Representations Rely on Integrative Coding

Li, A. Y.; Ladyka-Wojcik, N.; Qazilbash, H.; Golestani, A.; Walther, D. B.; Martin, C. B.; Barense, M. D.

10.1101/2022.08.31.504599 — neuroscience — Posted on 2022-09-01

4161 Oculomotor and neural correlates of semantic and morphological priming in natural sentence reading

Marjanovic, K.; Vidal, Y.; Crepaldi, D.

10.1101/2022.08.31.506138 — neuroscience — Posted on 2022-09-01

4162 Directed evolution of angiotensin-converting enzyme 2 (ACE2) peptidase activity profiles for therapeutic applications

Heinzelman, P.; Romero, P. A.

10.1101/2022.01.03.474817 — biochemistry — Posted on 2022-09-01

4163 Enhancers display constrained sequence flexibility and context-specific modulation of motif function

Reiter, F.; de Almeida, B. P.; Stark, A.

10.1101/2022.08.31.506061 — genomics — Posted on 2022-09-01

4164 Identification of conserved skeletal enhancers associated with craniosynostosis risk genes

He, X. A.; Berenson, A.; Bernard, M.; Weber, C.; Fuxman Bass, J.; Fisher, S.

10.1101/2022.09.01.506150 — genetics — Posted on 2022-09-01

4165 A 4-lineage statistical suite to evaluate the support of large-scale retrotransposon insertion data to reconstruct evolutionary trees

Churakov, G.; Kuritzin, A.; Chukharev, K.; Zhang, F.; Wunnemann, F.; Ulyantsev, V.; Schmitz, J.

10.1101/2020.12.10.419374 — evolutionary biology — Posted on 2022-09-01

4166 Outsourcing Memory Through Niche Construction

Lee, E. D.; Flack, J.; Krakauer, D.

10.1101/2022.09.01.506204 — evolutionary biology — Posted on 2022-09-01

4167 A cross-species study of sex chromosome dosage effects on mammalian brain anatomy

Guma, E.; Beauchamp, A.; Liu, S.; Levitis, E.; Clasen, L. S.; Torres, E.; Blumenthal, J.; Lalonde, F.; Qiu, L. R.; Hrncir, H.; MacKenzie-Graham, A. J.; Yang, X.; Arnold, A. P.; Lerch, J. P.; Raznahan, A.

10.1101/2022.08.30.505916 — neuroscience — Posted on 2022-09-01

4168 OPT3 Transports Copper to the Phloem, Mediates Shoot-to-Root Copper Signaling andCrosstalk Between Copper and Iron Homeostasis in A. thaliana

Vatamaniuk, O. K.; Chia, J.-C.; Yan, J.; Rahmati Ishka, M.; Faulkner, M. M.; Simons, E.; Huang, R.; Smieska, L. M.; Woll, A. R.; Tappero, R. V.; Kiss, A.; Jiao, C.; Fei, Z.; Pineros, M. A.; Kochian, L. V.; Walker, E. L.

10.1101/2021.07.30.454504 — plant biology — Posted on 2022-09-01

4169 Polymer brush bilayer under steady state shear motion: Density functional theory, scaling theory and molecular dynamic simulation

Edwards, M. J.

10.1101/2022.08.16.504146 — biophysics — Posted on 2022-09-01

4170 Polymer brush bilayers under stationary shear motion at linear response regime: A theoretical approach

Edwards, M.

10.1101/565796 — biophysics — Posted on 2022-09-01

4171 UniTVelo: temporally unified RNA velocity reinforces single-cell trajectory inference

Gao, M.; Qiao, C.; Huang, Y.

10.1101/2022.04.27.489808 — bioinformatics — Posted on 2022-09-01

4172 Concordance of MERFISH Spatial Transcriptomics with Bulk and Single-cell RNA Sequencing

Liu, J.; Tran, V.; Vemuri, V. N. P.; Byrne, A.; Borja, M.; Kim, Y. J.; Agarwal, S.; Wang, R.; Awayan, K.; Murti, A.; Taychameekiatchai, A.; Wang, B.; Emanuel, G.; He, J.; Haliburton, J.; Pisco, A. O.; Neff, N.

10.1101/2022.03.04.483068 — bioinformatics — Posted on 2022-09-01

4173 Long-read sequencing characterizes mitochondrial and plastid genome variants in Arabidopsis msh1 mutants

Zou, Y.; Zhu, W.; Sloan, D. B.; Wu, Z.

10.1101/2022.02.28.481893 — bioinformatics — Posted on 2022-09-01

4174 A low-cost, open-source evolutionary bioreactor and its educational use

Gopalakrishnan, V.; Crozier, D.; Card, K.; Chick, L.; Krishnan, N. P.; McClure, E.; Pelesko, J.; Williamson, D. F. K.; Nichol, D.; Mandal, S.; Bonomo, R. A.; Scott, J. G.

10.1101/729434 — bioengineering — Posted on 2022-09-01

4175 Co-obligate symbioses have repeatedly evolved across aphids, but partner identity and nutritional contributions vary across lineages

Manzano-Marin, A.; Coeur d'acier, A.; Clamens, A.-L.; Cruaud, C.; Barbe, V.; Jousselin, E.

10.1101/2022.08.28.505559 — genomics — Posted on 2022-09-01

4176 Partitioning genetic effects on birth weight at classical human leukocyte antigen loci into indirect maternal and direct fetal components using structural equation modelling

Wang, G.; Warrington, N. M.; Evans, D. M.

10.1101/2022.08.23.505053 — genetics — Posted on 2022-09-01

4177 Rapid intralacustrine evolution of an invasive pelagic three-spined stickleback (Gasterosteus aculeatus) ecotype in Lake Constance.

Dahms, C.; Roch, S.; Elmer, K. R.; Ros, A.; Brinker, A.; Jacobs, A.

10.1101/2022.09.01.506194 — evolutionary biology — Posted on 2022-09-01

4178 Environmental niche and demographic modeling of American chestnut near its southwestern range limit

Laport, R. G.; Brookover, Z. S.; Christman, B. D.; Ng, J.; Philley, K.; Craddock, J. H.

10.1101/2021.09.10.459451 — ecology — Posted on 2022-09-01

4179 Bisected graph matching improves automated pairing of bilaterally homologous neurons from connectomes

Pedigo, B. D.; Winding, M.; Priebe, C. E.; Vogelstein, J. T.

10.1101/2022.05.19.492713 — neuroscience — Posted on 2022-09-01

4180 Mechanisms and functions of respiration-driven gamma oscillations in the primary olfactory cortex

Gonzalez, J.; Torterolo, P.; Tort, A. B.

10.1101/2022.04.24.489324 — neuroscience — Posted on 2022-09-01

4181 Sustained attention as measured by RT variability is a strong modulator for the P600, but not the N400

Contier, F.; Weymar, M.; Wartenburger, I.; Rabovsky, M.

10.1101/2021.11.18.469143 — neuroscience — Posted on 2022-09-01

4182 How synaptic strength, short-term plasticity, and input synchrony contribute to neuronal spike output

Gastone Guilabert, A.; Buchholz, M. O.; Ehret, B.; Schuhknecht, G. F. P.

10.1101/2021.12.21.473708 — neuroscience — Posted on 2022-09-01

4183 Combining phenotypic and genomic data to improve prediction of binary traits

Jarquin, D.; Roy, A.; Clarke, B.; Ghosal, S.

10.1101/2022.08.30.505948 — genomics — Posted on 2022-09-01

4184 Effect of genomic and cellular environments on gene expression noise

Hong, C. K.; Ramu, A.; Zhao, S.; Cohen, B. A.

10.1101/2022.08.31.506082 — genomics — Posted on 2022-09-01

4185 Global Phylogeny of the Brassicaceae Provides Important Insights into Gene Discordance

10.1101/2022.09.01.506188 — evolutionary biology — Posted on 2022-09-01

4186 The rate of inversion fixation in plant genomes is highly variable.

Hirabayashi, K.; Owens, G. L.

10.1101/2022.08.31.506062 — evolutionary biology — Posted on 2022-09-01

4187 gUMI-BEAR, a modular, unsupervised population barcoding method to track variants and evolution at high resolution

Rezenman, S.; Knafo, M.; Tsigalnitski, I.; Barad, S.; Jona, G.; Levi, D.; Dym, O.; Reich, Z.; kapon, r.

10.1101/2022.09.01.506035 — evolutionary biology — Posted on 2022-09-01

4188 Flexible control of representational dynamics in a disinhibition-based model of decision making

Shen, B.; Louie, K.; Glimcher, P. W.

10.1101/2022.04.18.488670 — neuroscience — Posted on 2022-09-01

4189 Snip1 and PRC2 coordinate intrinsic apoptosis, cell division, and neurogenesis in the developing brain

Matsui, Y.; Djekidel, M. N.; Lindsay, K.; Samir, P.; Connolly, N.; Chen, H.; Fan, Y.; Xu, B.; Peng, J. C.

10.1101/2022.04.27.489801 — developmental biology — Posted on 2022-09-01

4190 Evolution of selfish multicellularity: collective organisation of individual spatio-temporal regulatory strategies

Vroomans, R. M.; Colizzi, E. S.

10.1101/2022.04.08.487695 — evolutionary biology — Posted on 2022-09-01

4191 Ultrasensitivity of Microtubule severing rate on the concentration of free Tubulin

Shiff, C. E.; Kondev, J.; Mohapatra, L.

10.1101/2022.04.26.488783 — cell biology — Posted on 2022-09-01

4192 Safe, effective, and inexpensive clearance of mycoplasma contamination from cultures of apicomplexan parasites with Sparfloxacin.

Malave-Ramos, D. R.; Kennedy, K.; Key, M. N.; Dou, Z.; Kafsack, B. F. C.

10.1101/2022.08.30.505931 — microbiology — Posted on 2022-09-01

4193 Regulation of prostate androgens by megalin and 25-hydroxyvitamin D status: Mechanism for high prostate androgen in African American men

Garcia, J.; Krieger, K.; Loitz, C.; Perez, L. M.; Richards, Z. A.; Helou, Y. B.; Kregel, S.; Selada, S.; Mesaros, C. A.; Gann, P.; Willnow, T. E.; Vander Griend, D.; Kittles, R.; Prins, G.; Penning, T.; Nonn, L.

10.1101/2021.11.09.467567 — cancer biology — Posted on 2022-09-01

4194 SARS-CoV-2 Omicron BA.2.75 variant may be much more infective than preexisting variants

Sugano, A.; Takaoka, Y.; Kataguchi, H.; Kumaoka, M.; Ohta, M.; Kimura, S.; Araki, M.; Morinaga, Y.; Yamamoto, Y.

10.1101/2022.08.25.505217 — bioinformatics — Posted on 2022-09-01

4195 Structural basis of nirmatrelvir and ensitrelvir resistance profiles against SARS-CoV-2 Main Protease naturally occurring polymorphisms

Noske, G. D.; Silva, E. S.; Godoy, M. O.; Dolci, I.; Fernandes, R. S.; Guido, R. V. C.; Sjo, P.; Oliva, G.; Godoy, A. S.

10.1101/2022.08.31.506107 — biochemistry — Posted on 2022-09-01

4196 Forebrain glucocorticoid receptor overexpression alters behavioral encoding of hippocampal CA1 pyramidal cells in mice

Gavade, S.; Wei, Q.; Johnston, C.; Kounelis, S.; Laborc, K.; Akil, H.; Spencer-Segal, J. L.

10.1101/2022.01.13.476185 — neuroscience — Posted on 2022-09-01

4197 Transcriptional response of circadian clock genes to an 'artificial light at night' pulse in the cricket Gryllus bimaculatus

Levy, K.; Fishman, B.; Barnea, A.; Ayali, A.; Tauber, E.

10.1101/2022.08.31.505991 — animal behavior and cognition — Posted on 2022-09-01

4198 Laboratory rearing alters activity and sleep patterns in the olive fruit fly

Terzidou, A. M.; Koveos, D. S.; Papadopoulos, N. T.; Carey, J. R.; Kouloussis, N. A.

10.1101/2022.08.31.506115 — animal behavior and cognition — Posted on 2022-09-01

4199 Multi-tissue landscape of somatic mtDNA mutations indicates tissue specific accumulation and removal in aging

Sanchez-Contreras, M.; Sweetwyne, M. T.; Tsantilas, K. A.; Whitson, J. A.; Campbell, M. D.; Kohrn, B. F.; Kim, H.-J.; Fredrickson, J.; Nguyen, M. M.; Hurley, J. B.; Marcinek, D. J.; Rabinovitch, P. S.; Kennedy, S. R.

10.1101/2022.08.30.505884 — genomics — Posted on 2022-09-01

4200 Mapping mitonuclear epistasis using a novel recombinant yeast population

Nguyen, T. H. M.; Tinz-Burdick, A.; Lenhardt, M.; Geertz, M.; Ramirez, F.; Schwartz, M.; Toledano, M.; Bonney, B.; Gaebler, B.; Liu, W.; Wolters, J. F.; Chiu, K.; Fiumera, A. C.; Fiumera, H.

10.1101/2022.08.31.505974 — evolutionary biology — Posted on 2022-09-01

4201 Arsenic induced alteration of neuroregulatory gene expression in Macrobrachium lamarrei: a neurotoxicological approach to grooming behaviour

Munshi, C.; Mukhuty, A.; Bandyopadhyay, A.; Bhowmik, A. D.; Mondal, P.; Shaw, P.; Bhattacharya, S.

10.1101/2022.08.30.505863 — pharmacology and toxicology — Posted on 2022-09-01

4202 Genetic control of RNA editing in Neurodegenerative disease

Wu, S.; Xue, Q.; Yang, M.; Wang, Y.; Kim, P.; zhou, X.; Huang, L.

10.1101/2022.08.31.505995 — bioinformatics — Posted on 2022-09-01

4203 Factors influencing patterns of gene expression in large bowel mucosa

Vaughan-Shaw, P.; Ooi, L.; Timofeeva, M.; Grimes, G.; Din, F. V.; Farrington, S. M.; Dunlop, M. G.

10.1101/2022.08.30.505238 — genomics — Posted on 2022-09-01

4204 Characterisation and Genetic Architecture of Major Depressive Disorder Subgroups Defined by Weight and Sleep Changes

Marshall, S.; Adams, M. J.; Evans, K. L.; Strawbridge, R. J.; McIntosh, A. M.; Thomson, P.

10.1101/2022.08.30.504498 — genomics — Posted on 2022-09-01

4205 Integrating sex-bias into studies of archaic admixture on chromosome X

Chevy, E. T.; Huerta-Sanchez, E.; Ramachandran, S.

10.1101/2022.08.30.505789 — evolutionary biology — Posted on 2022-09-01

4206 Assessing the utility of death assemblages as reference conditions in a common benthic index (M-AMBI) with simulations

Smith, J. A.; Pruden, M. J.; Handley, J. C.; Durham, S. R.; Dietl, G. P.

10.1101/2022.08.30.505344 — ecology — Posted on 2022-09-01

4207 Targeted multi-omic analysis of human skin tissue identifies alterations of conventional and unconventional T cells associated with burn injury

Labuz, D. R.; Lewis, G.; Fleming, I. D.; Thompson, C. M.; Zhai, Y.; Firpo, M. A.; Leung, D. T.

10.1101/2022.08.30.505800 — immunology — Posted on 2022-09-01

4208 NF-κB Decoy ODN-Loaded Poly lactic-co-glycolic Acid Nanospheres Inhibit Alveolar Ridge Resorption

Huang, A. C. S.; Ishida, Y.; Li, K.; Rintanalert, D.; Hatano-sato, K.; Oishi, S.; Hosomichi, J.; Usumi-Fujita, R.; Yamaguchi, H.; Tsujimoto, H.; Sasai, A.; Ochi, A.; Watanabe, H.; Ono, T.

10.1101/2022.08.30.505814 — immunology — Posted on 2022-09-01

4209 Adaptation of Dynamics in Default Mode Network Depending on Mental States: the one-to-many dynamic functional connectivity analysis with fMRI

Jeong, G.; Paolini, M.

10.1101/2022.08.30.505423 — neuroscience — Posted on 2022-09-01

4210 Walk the Plank! Using mobile EEG to investigate emotional lateralization of immersive fear in virtual reality

Basbasse, Y.; Packheiser, J.; Peterburs, J.; Maymon, C.; Guentuerkuen, O.; Grimshaw, G.; Ocklenburg, S.

10.1101/2022.08.30.505699 — neuroscience — Posted on 2022-09-01

4211 NBS-SNI, an extension of the Network-based statistic: Investigating differences in functional connections between important structural actors in case-control studies

Normand, F.; Cote, D. C.; Allard, A.

10.1101/2022.08.29.505749 — neuroscience — Posted on 2022-09-01

4212 Altered population activity and local tuning heterogeneity in auditory cortex of Cacna2d3-deficient mice

Wadle, S. L.; Schmitt, T. T.; Engel, J.; Kurt, S.; Hirtz, J. J.

10.1101/2022.08.30.505788 — neuroscience — Posted on 2022-09-01

4213 Improving fMRI in Parkinson's Disease by Accounting for Brain Region-Specific Activity Patterns

Torrecuso, R.; Mueller, K.; Sieger, T.; Vymazal, J.; Ruzicka, F.; Roth, J.; Ruzicka, E.; Schroeter, M. L.; Jech, R.; Möller, H. E.

10.1101/2022.08.30.505786 — neuroscience — Posted on 2022-09-01

4214 Glycemic challenge is associated with the rapid cellular activation of the locus ceruleus and nucleus of solitary tract: Circumscribed spatial analysis of phosphorylated MAP kinase immunoreactivity in relation to catecholaminergic and cholinergic chemoarchitecture

Tapia, G. P.; Agostinelli, L. J.; Chenausky, S. D.; Salcido Padilla, J. V.; Navarro, V. I.; Alagh, A.; Si, G.; Thompson, R. H.; Balivada, S.; Khan, A. M.

10.1101/2022.08.30.504809 — neuroscience — Posted on 2022-09-01

4215 Chromosomal and gonadal sex drive sex differences in lipids and hepatic gene expression in response to hypercholesterolemia and statin treatment

Wiese, C. B.; Agle, Z. W.; Zhang, P.; Reue, K.

10.1101/2022.08.29.505758 — physiology — Posted on 2022-09-01

4216 Cardiac pericytes are necessary for coronary vasculature integrity and cardiomyocyte differentiation

Cornuault, L.; Herion, F.-X.; Rouault, P.; Foussard, N.; Alzieu, P.; Chapouly, C.; Gadeau, A.-P.; Couffinhal, T.; Renault, M.-A.

10.1101/2022.08.29.505703 — physiology — Posted on 2022-09-01

4217 TMEM16A activation for the fast block to polyspermy in the African clawed frog does not require conventional activation of egg PLCs

Komondor, K. M.; Bainbridge, R. E.; Sharp, K. G.; Rosenbaum, J. C.; Carlson, A. E.

10.1101/2022.08.30.505853 — physiology — Posted on 2022-09-01

4218 Automatic Sample Segmentation & Detection of Parkinson's Disease Using Synthetic Staining & Deep Learning

Pearce, B. M.; Coetzee, P. L.; Rowland, D.; Dexter, D. T.; Gveric, D. O.; Gentleman, S.

10.1101/2022.08.30.505459 — pathology — Posted on 2022-09-01

4219 Folate receptor targeted nanoparticles containing niraparib and doxorubicin for treatment of high grade serous ovarian cancer

Wang, L.; Evans, J. C.; Ahmed, L.; Allen, C.

10.1101/2022.08.29.505711 — cancer biology — Posted on 2022-09-01

4220 Evolutionary states and trajectories characterized by distinct pathways stratify ovarian high-grade serous carcinoma patients

Lahtinen, A.; Lavikka, K.; Li, Y.; Virtanen, A.; Jamalzadeh, S.; Huhtinen, K.; Carpen, O.; Hietanen, S.; Häkkinen, A.; Hynninen, J.; Oikkonen, J.; Hautaniemi, S.

10.1101/2022.08.30.505808 — cancer biology — Posted on 2022-09-01

4221 Animal complexity defines the functionality of synonymous mutations through mediating microRNA regulations

Cui, C.; Lin, X.; Cui, Q.

10.1101/2022.08.30.505799 — bioinformatics — Posted on 2022-09-01

4222 The seeker R package: simplified fetching and processing of transcriptome data

Schoenbachler, J. L.; Hughey, J. J.

10.1101/2022.08.30.505820 — bioinformatics — Posted on 2022-09-01

4223 Inter-group Heterogeneity of Regional Homogeneity (REHO)

Jiang, Y.; Mhamdi, M. A. A.; Butler, R.

10.1101/2022.08.29.505722 — bioinformatics — Posted on 2022-09-01

4224 Sequence to graph alignment using gap-sensitive co-linear chaining

Chandra, G.; Jain, C.

10.1101/2022.08.29.505691 — bioinformatics — Posted on 2022-09-01

4225 HADEG: A Curated Database of Hydrocarbon Aerobic Degradation Enzymes and Genes

Rojas-Vargas, J.; Castelan-Sanchez, H. G.; Pardo-Lopez, L.

10.1101/2022.08.30.505856 — bioinformatics — Posted on 2022-09-01

4226 Prognostic association of immunoproteasome expression in solid tumours is governed by the immediate immune environment

Kumar, R.; Dhaka, B.; Sahoo, S.; Jolly, M. K.; Sabarinathan, R.

10.1101/2022.08.30.505767 — bioinformatics — Posted on 2022-09-01

4227 New algorithms for accurate and efficient de-novo genome assembly from long DNA sequencing reads

Gonzalez-Garcia, L. N.; Guevara-Barrientos, D.; Lozano-Arce, D.; Gil, J.; Diaz-Riano, J.; Duarte, E.; Andrade, G.; Bojaca, J. C.; Hoyos, M. C.; Chavarro, C.; Guayazan, N.; Chica, L. A.; Buitrago Acosta, M. C.; Bautista, E.; Trujillo, M.; Duitama, J.

10.1101/2022.08.30.505891 — bioinformatics — Posted on 2022-09-01

4228 KMer-Node2Vec: Learning Vector Representations of K-mers from the K-meGraph

Yu, Z.; Yang, Z.; Lan, Q.; Huang, F.; Cai, Y.

10.1101/2022.08.30.505832 — bioinformatics — Posted on 2022-09-01

4229 Label-free imaging of 3D pluripotent stem cell differentiation dynamics on chip

Atwell, S.; Waibel, D. J. E.; Shetab Boushehri, S.; Marr, C.; Meier, M.

10.1101/2022.08.30.505835 — bioinformatics — Posted on 2022-09-01

4230 Optimized Monophasic Pulses with Equivalent Electric Field for Rapid-Rate Transcranial Magnetic Stimulation

Wang, B.; Zhang, J.; Li, Z.; Grill, W. M.; Peterchev, A. V.; Goetz, S. M.

10.1101/2022.08.29.503248 — bioengineering — Posted on 2022-09-01

4231 A red fluorescent genetically encoded biosensor for extracellular L-lactate

Nasu, Y.; Kamijo, Y.; Hashizume, R.; Sato, H.; Hori, Y.; Tomita, T.; Drobizhev, M.; Campbell, R. E.

10.1101/2022.08.30.505811 — bioengineering — Posted on 2022-09-01

4232 Defining a Nonribosomal Specificity Code for Design

Stanisic, A.; Svensson, C.-M.; Ettelt, U.; Kries, H.

10.1101/2022.08.30.505883 — bioengineering — Posted on 2022-09-01

4233 Mesenchymal stem cell culture within perfusion bioreactors incorporating 3D-printed scaffolds enables improved extracellular vesicle yield with preserved bioactivity

Kronstadt, S. M.; Patel, D. B.; Born, L. J.; Levy, D.; Lerman, M. J.; Mahadik, B.; McLoughlin, S. T.; Fasuyi, A.; Fowlkes, L.; Hoorens van Heyningen, L.; Aranda, A.; Abadchi, S. N.; Chang, K.-H.; Hsu, A. T. W.; Bengali, S.; Harmon, J. W.; Fisher, J. P.; Jay, S. M.

10.1101/2022.08.30.505860 — bioengineering — Posted on 2022-09-01

4234 Mera: A scalable high throughput automated micro-physiological system

Cliffe, F.; Costello, P.; Madden, C.; Devitt, S.; Mukkunda, S. R.; Keshava, B. B.; Fearnhead, H.; Vitkuaskaite, A.; Dehkordi, M.; Chingwaru, W.; Przyjalgowski, M.; Rebrova, N.; Lyons, M.

10.1101/2022.08.30.505827 — bioengineering — Posted on 2022-09-01

4235 An oligogenic architecture underlying ecological and reproductive divergence in sympatric populations

Brisevac, D.; Peralta, C. M.; Kaiser, T. S.

10.1101/2022.08.30.505825 — evolutionary biology — Posted on 2022-09-01

4236 Relictual Hybridization and Biogeography of Massasauga Rattlesnakes (Sistrurus spp.)

Martin, B. T.; Douglas, M. R.; Chafin, T. K.; Placyk, J. S.; Mackessy, S. P.; Briggler, J. T.; Douglas, M. E.

10.1101/2022.08.29.505772 — evolutionary biology — Posted on 2022-09-01

4237 Durable resistance or efficient disease control?Adult Plant Resistance (APR) at the heart of the dilemma

Rimbaud, L.; Papaïx, J.; Rey, J.-F.; Moury, B.; Barrett, L. G.; Thrall, P. H.

10.1101/2022.08.30.505787 — evolutionary biology — Posted on 2022-09-01

4238 Environmentally robust cis-regulatory changes underlie rapid climatic adaptation

Ballinger, M. A.; Mack, K. L.; Durkin, S. M.; Riddell, E. A.; Nachman, M. W.

10.1101/2022.08.29.505745 — evolutionary biology — Posted on 2022-09-01

4239 Rodent trapping studies as an overlooked information source for understanding endemic and novel zoonotic spillover.

Simons, D.; Attfield, L. A.; Jones, K. E.; Watson-Jones, D.; Kock, R.

10.1101/2022.08.30.505792 — ecology — Posted on 2022-09-01

4240 Mosquito invasion via the global shipping network is slowed in high-risk areas by on-shore and ship-board monitoring

Willoughby, J.; McKenzie, B.; Ahn, J.; Steury, T.; Lepzcyk, C.; Zohdy, S.

10.1101/2022.08.29.505734 — ecology — Posted on 2022-09-01

4241 Agricultural and urban land use explain substantial variation in lake water quality across national-scale physiographic and climatic gradients

Sanchez Schacht, J. R.; MacKeigan, P. W.; Taranu, Z. E.; Huot, Y.; Gregory-Eaves, I.

10.1101/2022.08.29.505280 — ecology — Posted on 2022-09-01

4242 LSD-induced increase of Ising temperature and algorithmic complexity of brain dynamics

Ruffini, G.; Damiani, G.; Lozano-Soldevilla, D.; Deco, N.; Rosas, F.; Kiani, N.; Ponce-Alvarez, A.; Kringelbach, M. L.; Carhart-Harris, R.; Deco, G. L.

10.1101/2022.08.27.505518 — neuroscience — Posted on 2022-09-01

4243 The calcineurin regulator Sarah enables acute and chronic forms of homeostatic plasticity at the Drosophila neuromuscular junction

Armstrong, N. S.; Frank, C. A.

10.1101/2022.08.31.506100 — neuroscience — Posted on 2022-09-01

4244 PEZO-1 and TRP-4 mechanosensors are involved in mating behavior in Caenorhabditis elegans

Brugman, K. I.; Susoy, V.; Whittaker, A. J.; Palma, W.; Nava, S.; Samuel, A. D.; Sternberg, P. W.

10.1101/2022.08.31.506045 — neuroscience — Posted on 2022-09-01

4245 CDKL5 deficiency results in atypical subregion-specific expression of perineuronal nets in the mouse primary visual cortex

Emery, B. A.; Everett, M.; Lau, B. Y. B.; Krishnan, K.

10.1101/2022.08.31.505900 — neuroscience — Posted on 2022-09-01

4246 Silencing long-descending inter-enlargement propriospinal neurons improves hindlimb stepping after contusive spinal cord injuries

Shepard, C. T.; Brown, B. L.; Van Rijswijck, M. A.; Zalla, R. M.; Burke, D. A.; Morehouse, J. R.; Riegler, A. S.; Whittemore, S. R.; Magnuson, D. S.

10.1101/2022.08.30.505848 — neuroscience — Posted on 2022-09-01

4247 Norepinephrine regulates Ca2+ signals and fate of oligodendrocyte progenitor cells in the cortex

Fiore, F.; Dereddi, R. R.; Alhalaseh, K.; Coban, I.; Harb, A.; Agarwal, A.

10.1101/2022.08.31.505555 — neuroscience — Posted on 2022-09-01

4248 Boolean modeling of mechanosensitive Epithelial to Mesenchymal Transition and its reversal

Sullivan, E.; Harris, M.; Bhatnagar, A.; Guberman, E.; Zonfa, I.; Ravasz Regan, E.

10.1101/2022.08.29.505701 — systems biology — Posted on 2022-09-01

4249 Increased academic performance and prolonged career duration among Taiwanese academic faculty in ecology and evolutionary biology

Hsu, G.-C.; Lin, W.-J.; Sun, S.-J.

10.1101/2022.01.31.478501 — scientific communication and education — Posted on 2022-09-01

4250 Mapping the adaptor protein complex interaction network in Arabidopsis identifies P34 as a common stability regulator

Wang, P.; Siao, W.; Zhao, X.; Arora, D.; Wang, R.; Eeckhout, D.; Van Leene, J.; Kumar, R.; Houbaert, A.; De Winne, N.; Mylle, E.; Vandorpe, M.; Korver, R. A.; Testerink, C.; Gevaert, K.; Vanneste, S.; De Jaeger, G.; Van Damme, D.; Russinova, E.

10.1101/2022.08.31.505729 — plant biology — Posted on 2022-09-01

4251 PNuts: Global spatio-temporal database of plant nutritional properties

Berzaghi, F.; Bretagnolle, F.; Ratshikombo, Z.; Ben Abdallah, A.

10.1101/2022.08.29.505708 — plant biology — Posted on 2022-09-01

4252 Low polyethylene glycol (PEG) concentration contributes to photoprotection in Chlamydomonas reinhardtii under highlight stress.

Xavier, J.; YADAV, R. M.; Subramanyam, R.

10.1101/2022.08.30.505872 — plant biology — Posted on 2022-09-01

4253 X chromosome dosage drives statin-induced dysglycemia and mitochondrial dysfunction

Zhang, P.; Munier, J. J.; Vergnes, L.; Wiese, C. B.; Link, J. C.; Abbasi, F.; Ronquillo, E.; Munoz, A.; Kuang, Y.-L.; Liu, M.; Sanchez, G.; Oni-Orisan, A.; Iribarren, C.; McPhaul, M. J.; Nomura, D. K.; Knowles, J. W.; Krauss, R. M.; Medina, M. W.; Reue, K.

10.1101/2022.08.29.505759 — physiology — Posted on 2022-09-01

4254 Hepatic fibrosis induced zinc-deficient dermatosis in American alligators (Alligator mississippiensis)

Piras, I. M.; Bezuidenhout, A.; Diaz-Delgado, J.; Slawski, D.; Kelly, P. A.

10.1101/2022.08.30.505809 — pathology — Posted on 2022-09-01

4255 Fetal QRS Detection by Multiple Channel Temporal Pattern Search Applied to the NInFEA Database

Hopenfeld, B. R.

10.1101/2022.08.29.505738 — bioengineering — Posted on 2022-09-01

4256 Development of novel temporal beta-diversity indices for assessing community compositional shifts accounting for changes in the properties of individuals

Nakadai, R.

10.1101/2022.04.13.488244 — ecology — Posted on 2022-09-01

4257 Transcriptome changes in chlorsulfuron-treated plants are caused by acetolactate synthase inhibition and not induction of a herbicide detoxification system in Marchantia polymorpha

Casey, A.; Köcher, T.; Caygill, S.; Champion, C.; Bonnot, C.; Dolan, L.

10.1101/2022.08.31.505973 — plant biology — Posted on 2022-09-01

4258 Effective root responses to salinity stress include maintained cell expansion and carbon allocation

Li, H.; Duijts, K.; Pasini, C.; van Santen, J. E.; Wang, N.; Zeeman, S. C.; Santelia, D.; Zhang, Y.; Testerink, C.

10.1101/2022.09.01.506200 — plant biology — Posted on 2022-09-01

4259 Characterization of peptide-protein relationships in protein ambiguity groups via bipartite graphs

Schork, K.; Turewicz, M.; Uszkoreit, J.; Rahnenführer, J.; Eisenacher, M.

10.1101/2021.07.28.454128 — bioinformatics — Posted on 2022-09-01

4260 A low-cost, open-source evolutionary bioreactor and its educational use

Gopalakrishnan, V.; Guo, D.; Card, K.; Chick, L.; Krishnan, N. P.; McClure, E.; Pelesko, J.; Williamson, D. F. K.; Nichol, D.; Mandal, S.; Bonomo, R. A.; Scott, J. G.

10.1101/729434 — bioengineering — Posted on 2022-09-01

4261 Spatial Transcriptomics Using Multiplexed Deterministic Barcoding in Tissue

Wirth, J.; Compera, N.; Yin, K.; Brood, S.; Chang, S.; Martinez-Jimenez, C. P.; Meier, M.

10.1101/2022.08.30.505834 — genomics — Posted on 2022-09-01

4262 Nucleotide and structural polymorphisms of the eastern oyster genome paint a mosaic of divergence, selection, and human impacts

Puritz, J. B.; Zhao, H.; Guo, X.; Hare, M. P.; He, Y.; LaPeyre, J.; Lotterhos, K. E.; Lundgren, K. M.; Modak, T.; Proestou, D. A.; Rawson, P.; Fernandez Robledo, J. A.; Witkop, E.; Weedop, K. B.; Gomez-Chiarri, M.

10.1101/2022.08.29.505629 — evolutionary biology — Posted on 2022-09-01

4263 Can growth in captivity alter the calcaneal microanatomy of a wild ungulate?

Cottereau, R.; Houssaye, A.; Cucchi, T.; Locatelli, Y.; Ortiz, K.

10.1101/2022.08.22.504790 — developmental biology — Posted on 2022-09-01

4264 Intestinal stem cell aging at single-cell resolution: functional perturbations alter cell developmental trajectory reversed by gerotherapeutics

Choi, J.; Houston, M.; Wang, R.; Ye, K.; Li, W.; Zhang, X.; Huffman, D. M.; Augenlicht, L. H.

10.1101/2022.08.31.505869 — cell biology — Posted on 2022-09-01

4265 Physical association of low density lipoprotein particles and extracellular vesicles unveiled by single particle analysis

Lozano-Andres, E.; Enciso-Martinez, A.; Gijsbers, A.; Libregts, S. F. W. M.; Pinheiro, C.; van Niel, G.; Hendrix, A.; Peters, P. J.; Otto, C.; Arkesteijn, G. J. A.; Wauben, M.

10.1101/2022.08.31.506022 — cell biology — Posted on 2022-09-01

4266 Myoglobin promotes cardiomyocyte differentiation through oxidatively modulating the Hippo Kinase Pathway

Rao, K.; Rochon, E.; Singh, A.; Jagnnathan, R.; Peng, Z.; Moulik, M.; Zhang, M.; Corti, P.; Shiva, S.

10.1101/2022.08.31.506050 — cell biology — Posted on 2022-09-01

4267 Molecular regulation of GPCR-G-protein-governed PIP3 generation and its adaptation

Wijayaratna, D.; Ratnayake, K.; Ubeysinghe, S.; Kankanamge, D.; Tennakoon, M.; Karunarathne, A.

10.1101/2022.08.31.506078 — cell biology — Posted on 2022-09-01

4268 mTOR pathway inhibition stimulates pharmacologically induced nonsense suppression

Wittenstein, A.; Caspi, M.; Rippin, I.; Elroy-Stein, O.; Eldar-Finkelmn, H.; Thoms, S.; Rosin-Arbesfeld, R.

10.1101/2022.08.31.506003 — cell biology — Posted on 2022-09-01

4269 Nogo-A regulates the fate of human dental pulp stem cells towards osteogenic, adipogenic, and neurogenic differentiation

Shen, J.; Lai, C. F.; Balic, A.; Pagella, P.; Schwab, M. E.; Mitsiadis, T.

10.1101/2022.09.01.506142 — cell biology — Posted on 2022-09-01

4270 Natural and pathological aging distinctively impact the vomeronasal system and social behavior

Portales, A.; Chamero, P.; Jurado, S.

10.1101/2022.08.31.505522 — neuroscience — Posted on 2022-09-01

4271 SARS-CoV-2 Omicron BA.2.75 variant may be much more infective than preexisting variants

Sugano, A.; Takaoka, Y.; Kataguchi, H.; Kumaoka, M.; Ohta, M.; Kimura, S.; Araki, M.; Morinaga, Y.; Yamamoto, Y.

10.1101/2022.08.25.505217 — bioinformatics — Posted on 2022-09-01

4272 Impact of reinfection with SARS-CoV-2 Omicron variants in previously infected hamsters

Shiwa-Sudo, N.; Sakai, Y.; Iwata-Yoshikawa, N.; Watanabe, S.; Yamada, S.; Kuroda, Y.; Yamamoto, T.; Shirakura, M.; Fujisaki, S.; Miyazaki, K.; Miura, H.; Nagata, S.; Fukushi, S.; Maeda, K.; Hasegawa, H.; Suzuki, T.; Nagata, N.

10.1101/2022.08.30.505966 — microbiology — Posted on 2022-09-01

4273 Voltage clamp fluorometry analysis of the P2X7 receptor suggests a limited conformational interplay between extracellular ATP binding and the intracellular ballast domain

Durner, A.; Durner, E.; Nicke, A.

10.1101/2022.08.31.506013 — biophysics — Posted on 2022-09-01

4274 Mutations in CmVPS41 controlling resistance to Cucumber Mosaic Virus display specific subcellular localization

Real, N.; Villar, I.; Serrano, I.; Guiu-Aragones, C.; Martin-Hernandez, A. M.

10.1101/2022.08.30.505877 — cell biology — Posted on 2022-09-01

4275 Cleavage of 14-3-3ϵ by the enteroviral 3C protease dampens RIG-I mediated antiviral signaling

Andrews, D. D.; Mohamud, Y.; Vlok, M.; Akbari Bani, D.; Hay, B. N.; Foster, L. J.; Luo, H.; Overall, C. M.; Jan, E.

10.1101/2022.08.31.505975 — microbiology — Posted on 2022-09-01

4276 Lateral line hair cells integrate mechanical and chemical cues to orient navigation

Desban, L.; Roussel, J.; Mirat, O.; Lejeune, F.-X.; Keiser, L.; Michalski, N. A.; Wyart, C.

10.1101/2022.08.31.505989 — neuroscience — Posted on 2022-09-01

4277 Quantification of Monosynaptic Rabies Tracing Efficiency

Patino, M.; Lagos, W. N.; Patne, N. S.; Miyazaki, P. A.; Callaway, E.

10.1101/2022.08.31.506012 — neuroscience — Posted on 2022-09-01

4278 An electrophysiological and kinematic model of Paramecium, the "swimming neuron"

Elices, I.; Kulkarni, A.; Escoubet, N.; Pontani, L.-L.; Prevost, A. M.; Brette, R.

10.1101/2022.02.15.480485 — neuroscience — Posted on 2022-09-01

4279 Sentences, Words, Attention: A "Transforming" Aphorism for the Discovery of pre-miRNA Regions across Plant Genomes

Gupta, S.; Saini, V.; Kumar, R.; Shankar, R.

10.1101/2022.07.14.500029 — bioinformatics — Posted on 2022-09-01

4280 Chimpanzees communicate to coordinate a cultural practice

Goldsborough, Z.; Schel, A. M.; J.C. van Leeuwen, E.

10.1101/2021.03.22.436386 — animal behavior and cognition — Posted on 2022-09-01

4281 Hybridization drives mitochondrial DNA degeneration and metabolic shift in a species with biparental mitochondrial inheritance

Henault, M.; Marsit, S.; Charron, G.; Landry, C. R.

10.1101/2022.04.29.490087 — genomics — Posted on 2022-09-01

4282 Environmental response in gene expression and DNA methylation reveals factors influencing the adaptive potential of Arabidopsis lyrata

Hämälä, T.; Ning, W.; Kuittinen, H.; Aryamanesh, N.; Savolainen, O.

10.1101/2022.03.24.485516 — evolutionary biology — Posted on 2022-09-01

4283 MATEdb, a data repository of high-quality metazoan transcriptome assemblies to accelerate phylogenomic studies

Fernandez, R.; Tonzo, V.; Simon Guerrero, C.; Lozano-Fernandez, J.; Martinez-Redondo, G. I.; Balart-Garcia, P.; Aristide, L.; Eleftheriadi, K.; Vargas-Chavez, C.

10.1101/2022.07.18.500182 — evolutionary biology — Posted on 2022-09-01

4284 Fragmented habitat compensates for the adverse effects of genetic bottleneck

Löytynoja, A.; Rastas, P.; Valtonen, M.; Kammonen, J.; Holm, L.; Tange Olsen, M.; Paulin, L.; Jernvall, J.; Auvinen, P.

10.1101/2022.04.05.487133 — evolutionary biology — Posted on 2022-09-01

Archive, 2022-09