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Archive, 2025-06

2 Regulators of Interferon-Responsive Microglia Uncovered by Genome-wide CRISPRi Screening
McQuade, A.; Castillo, V. C.; Hagan, V.; Liang, W.; Ta, T.; Mishra, R.; Teter, O.; Teyssier, N.; Leng, K.; Kampmann, M.
10.1101/2025.06.05.658176 — neuroscience — Posted on 2025-06-06
3 Neural coding of spectrotemporal modulations in the auditory cortex supports speech and music categorization
Ginzburg, J.; Debaque, E. C.; Borderie, A.; Morillon, B.; Martineau, L.; Bonaventure, P. L.; Albouy, P.; Zatorre, R.
10.1101/2025.06.05.657930 — neuroscience — Posted on 2025-06-06
5 Increasing Stemness Drives Prostate Cancer Progression, Plasticity, Therapy Resistance and Poor Patient Survival
Liu, X.; Cortes, E.; Ji, Y.; Zhao, K.; Ho, J.; Liu, Y. S.; Davicioni, E.; Feng, F. Y.; Alumkal, J. J.; Spratt, D. E.; Sweeney, C. J.; Yu, H.; Hu, Q.; Cheng, Z.; Zhang, D.; Chatta, G.; Nastiuk, K. L.; Goodrich, D. W.; Rycaj, K.; Jamroze, A.; Kirk, J. S.; Puzanov, I.; Liu, S.; Wang, J.; Tang, D. G.
10.1101/2025.04.27.650697 — cancer biology — Posted on 2025-06-06
9 Spontaneous cell morphogenesis via self-propelled actin filaments
Yagami, K.; Baba, K.; Minegishi, T.; Misu, S.; Katsuno-Kambe, H.; Okano, K.; Sakumura, Y.; Hosokawa, Y.; Inagaki, N.
10.1101/2024.02.28.582450 — cell biology — Posted on 2025-06-06
10 Towards Unified Neural Decoding with Brain Functional Network Modeling
Wu, D.; Bu, L.; Jia, Y.; Cao, L.; Li, S.; Zhou, Y.; Fan, S.; Ren, W.; Wu, D.; Wang, K.; Zhang, Y.; Ma, Y.; Yang, J.; Sawan, M.
10.1101/2025.06.02.657011 — neuroscience — Posted on 2025-06-05
12 Phosphoproteome modifications and cortical circuit dysfunction are linked to the early-stage progression of alpha-synuclein aggregation.
Dutta, S.; Hensel, J.; Scott, A.; Mohallem, R.; Rossitto, L.-A. M.; Khan, H. F.; Johnson, T.; Ferreira, C. R.; Diehl, L. A.; Marmolejo, J. F.; Chen, X.; Jayant, K.; Aryal, U. K.; Volpicelli-Daley, L.; Rochet, C.
10.1101/2025.01.24.634820 — neuroscience — Posted on 2025-06-06
13 A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype
Cho, W.; Liu, J. Y.; Beckett, A. N.; Lunger, J. C.; Xu, P.; Ho, K.; Chen, E. E.; Salcido-Alcantar, A.; Sant'Anna, L. E.; Obbad, K.; Po, N.; Sotillo, E.; Mackall, C. L.; Daniels, K. G.
10.1101/2025.06.05.658149 — synthetic biology — Posted on 2025-06-05
14 Non-Invasive Mechanical-Functional Analysis of Individual Liver Mitochondria by Atomic Force Microscopy
Zorikova, E. O.; Chourasia, S.; Rosenhek-Goldian, I.; Cohen, S. R.; Nesterov, S. V.; Gross, A.
10.1101/2025.06.01.657242 — biophysics — Posted on 2025-06-05
16 De novo design of miniprotein agonists and antagonists targeting G protein-coupled receptors
Muratspahic, E.; Feldman, D.; Kim, D. E.; Qu, X.; Bratovianu, A.-M.; Rivera-Sanchez, P.; Dimitri, F.; Cao, J.; Cary, B. P.; Belousoff, M. J.; Keov, P.; Chen, Q.; Ren, Y.; Fine, J.; Sappington, I.; Schlichthaerle, T.; Zhang, J. Z.; Pillai, A.; Mihaljevic, L.; Bauer, M.; Torres, S. V.; Motmaen, A.; Lee, G. R.; Tran, L.; Wang, X.; Goreshnik, I.; Vafeados, D. K.; Svendsen, J. E.; Hosseinzadeh, P.; Lindegaard, N.; Brandt, M.; Waltenspühl, Y.; Deibler, K.; Oostdyk, L.; Cao, W.; Anantharaman, L.; Stewart, L.; Halloran, L.; Spangler, J. B.; Sexton, P. M.; Roth, B. L.; Krumm, B. E.; Wootten, D.; Tate,
10.1101/2025.03.23.644666 — bioengineering — Posted on 2025-06-05
17 Deciphering the thiolactonization mechanism in thiolactomycin biosynthesis
Guo, J.; Zhang, Q.; Shen, Y.; Cheng, F.; Sang, M.; Wang, X.; Pan, Y.; Liu, M.; Yu, H.-B.; Hu, B.; Wang, S.; Zheng, L.; Geng, C.; Yang, C.; Luo, L.; Zhang, G.; Du, L.; Li, Y.; Zhang, W.; Zhang, Y.; Wang, B.; Li, S.; Zhang, X.
10.1101/2024.12.18.629141 — biochemistry — Posted on 2025-06-05
19 Inhalable Perfluorocarbon Nanocapsules for RNA-based Immunotherapeutic Treatment of Lung Metastases
Siddhanta, K.; Monirvaghef, A.; Sundar, A.; Pinkerton, B. R.; Kumari, N.; Ding, L.; Woslager, C. J.; Kalpana, M. A.; Jogdeo, C. M.; Ravnholdt, A. R.; Poole, J. A.; Santarpia, J.; Talmadge, J. E.; Oupicky, D.
10.1101/2025.06.05.658088 — bioengineering — Posted on 2025-06-05
20 Aromatic Patch in WhiB-Like Transcription Factors Facilitates Primary Sigma Factor Interaction in Mycobacterium tuberculosis
Beltran, D. G.; Wan, T.; Seravalli, J.; Horova, M.; Jones, C.; Li, S.; Ma, P.; Becker, D.; Mower, J. P.; Yao, Q.; Pan, Y.; Yu, H.; Steyn, A. J.; Zhang, L.
10.1101/2025.06.05.653497 — biochemistry — Posted on 2025-06-05
21 Changes in biophysical characteristics of YghA from E. coli due to variation in pH
Hasan, N.; Jilani, S. B.; Saeed, S.; Stoner, M. R.; Yazdani, S. S.; Choi, Y.; Khan, R. H.
10.1101/2025.06.05.657471 — biochemistry — Posted on 2025-06-05
26 RNA structure directs RNA partitioning and is actively disrupted inside stress granules to enable cellular recovery
Zhu, B.; Lim, J. J. A.; Zhang, Y.; Tan, W. T.; Zhang, J.; Xiang, J. S. N.; Huber, R.; Khong, A.; Wan, Y.
10.1101/2025.06.05.658090 — molecular biology — Posted on 2025-06-05
32 A continuous landscape of signaling encodes a corresponding landscape of CAR T cell phenotype
Cho, W.; Liu, J. Y.; Beckett, A. N.; Lunger, J. C.; Xu, P.; Ho, K.; Chen, E. E.; Salcido-Alcantar, A.; Sant'Anna, L. E.; Obbad, K.; Po, N.; Sotillo, E.; Mackall, C. L.; Daniels, K. G.
10.1101/2025.06.05.658149 — synthetic biology — Posted on 2025-06-05
36 The Immunophenotype and Proviral Landscape of HIV-infected CD4 T Cells During Antiretroviral Therapy
Delley, C. L.; Shah, S.; Joslin, K. M.; Park, Y. P.; Busch, M. P.; Stone, M.; Demaree, B.; Deeks, S. G.; Boritz, E. A.; Abate, A. R.; Clark, I. C.
10.1101/2025.06.05.657210 — genomics — Posted on 2025-06-05
39 Evaluation of Enterobacterales carrying Acinetobacter-associated blaOXA genes--United States, 2017-2022
Orazi, G.; Kent, A. G.; Wilmott, N.; Berhe, D.; Longo, C.; Bumpus-White, P.; Rutledge, D.; Hovan, G.; Villegas Correa, I. M.; Otero Pagan, I.; Coe, P.; Therrien, M.; Bhatnagar, A.; McKay, S. L.; Brown, A. C.; Laufer Halpin, A.; Sabour, S.
10.1101/2025.06.05.655513 — microbiology — Posted on 2025-06-05
41 Training-induced alterations in the modulation of human motoneuron discharge patterns with contraction force
Skarabot, J.; Thomason, H.; Nazaroff, B. M.; Connelly, C. D.; Valencic, T.; Ho, M. L.; Tyagi, K.; Beauchamp, J. A.; Pearcey, G. E.
10.1101/2025.06.02.657380 — neuroscience — Posted on 2025-06-05
42 Cell-surface proteomic profiling identifies CD72 as a regulator of microglial tiling
Chan, T. C.; Rastogi, M.; Williams, M. X.; Zhang, S.; Shi, S. M.; Shuken, S. R.; Bartling, T.; Wild, K.; Atkins, M.; Hahn, O.; Paulo, J. A.; Jereb, S.; Shuster, S. A.; Yoo, Y.; Napole, A.; Hernandez, V. G.; Luo, L.; Buckwalter, M. S.; Stevens, B.; Deverman, B. E.; Kronenberg-Versteeg, D.; Gygi, S. P.; Wyss-Coray, T.; Wernig, M.
10.1101/2025.06.02.657480 — neuroscience — Posted on 2025-06-05
44 A resource and computational approach for quantifying gene editing allelism at single-cell resolution
Ung, M. H.; Angelini, G.; Wang, R.; Pyclik, A.; Lydeard, J. R.; Ferrucio, J. X.; Lin, M. I.; Chakraborty, T.; Ge, H. G.
10.1101/2025.05.22.653824 — bioinformatics — Posted on 2025-06-05
47 Plasma insulin-like growth-factor 1 (IGF-1) concentrations predict early life-history traits in a wild mammal
Ravindran, S.; Corripio-Miyar, Y.; Pick, J. L.; Bal, X.; Pilkington, J. G.; Pemberton, J. M.; Nussey, D. H.; Froy, H.
10.1101/2025.06.02.656453 — ecology — Posted on 2025-06-05
48 Mid-infrared chemical imaging of living cells enabled by plasmonic metasurfaces
Huang, S. H.; Shen, P.-T.; Mahalanabish, A.; Sartorello, G.; Li, J.; Liu, X.; Shvets, G.
10.1101/2024.09.17.613596 — cell biology — Posted on 2025-06-05
49 Immunofocusing on the conserved fusion peptide of HIV envelope glycoprotein in rhesus macaques
Pratap, P. P.; Cottrell, C. A.; Quinn, J.; Carnathan, D. G.; Bader, D. L. V.; Tran, A. S.; Enemuo, C. A.; Ngo, J. T.; Richey, S. T.; Gao, H.; Shen, X.; Greene, K. M.; Hurtado, J.; Michaels, K. K.; Ben-Akiva, E.; Lemnios, A.; Melo, M. B.; Allen, J. D.; Ozorowski, G.; Crispin, M.; Briney, B.; Montefiori, D.; Silvestri, G.; Irvine, D. J.; Crotty, S.; Ward, A. B.
10.1101/2024.11.27.625755 — immunology — Posted on 2025-06-05
50 PointTree: Automatic and accurate reconstruction of long-range axonal projections of single-neuron
Cai, L.; Fan, T.; Qu, X.; Zhang, Y.; Gou, X.; Ding, Q.; Feng, W.; Cao, T.; Lv, X.; Liu, X.; Huang, Q.; Quan, T.; Zeng, S.
10.1101/2024.09.23.614432 — neuroscience — Posted on 2025-06-05
53 Redistribution of fragmented mitochondria ensure symmetric organelle partitioning and faithful chromosome segregation in mitotic mouse zygotes
Gekko, H.; Nomura, R.; Kuzuhara, D.; Kaneyasu, M.; Koseki, G.; Adhikari, D.; Mio, Y.; Carroll, J.; Kono, T.; Funahashi, H.; Wakai, T.
10.1101/2024.06.13.598818 — developmental biology — Posted on 2025-06-05
54 Novel Adomaviruses Associated with Blotchy Bass Syndrome in Black Basses (Micropterus spp.)
Iwanowicz, L. R.; Raines, C. D.; Young, K. T.; Blazer, V. S.; Walsh, H. L.; Smith, G.; Holt, C.; Odenkirk, J.; Jones, T.; Hessenauer, J.-M.; Biggs, M.; Buck, C. B.; Greer, J.; Cornman, R. S.
10.1101/2025.06.01.657292 — microbiology — Posted on 2025-06-05
55 Characterization of Sex-Based Differences in Integrin-Mediated Endothelial Cell Adhesion to Bioactive Hydrogels
Nkansah, A.; Budhwani, A.; Grammer, N.; Ang, N.; Fairley, A.; Salazar, S. P.; Anand, A.; Yedalla, A. C.; Seidlits, S.; Allen, J.; Cosgriff-Hernandez, E.
10.1101/2025.06.02.656802 — bioengineering — Posted on 2025-06-05
56 The impact of RNA chemical probing reagents on RNA binding proteins
Klingler, D.; Fallon, L.; Cohn, D.; Crawford, A.; Marcus, L.; Jones, A. N.
10.1101/2024.03.21.586119 — biochemistry — Posted on 2025-06-05
58 CBP-IDRs regulate acetylation and gene expression.
Gelder, K. L.; Carruthers, N. A.; Gilbert, G.; Harrison, L. J.; Evans, T.; Ball, S. S.; Dunning, M.; Craggs, T. D.; Twelvetrees, A. E.; Bose, D. A.
10.1101/2024.06.04.597392 — molecular biology — Posted on 2025-06-05
59 Mutant Huntingtin exon1 protein detected in mouse brain with neoepitope antibody: effects of CAG repeat expansion, MSH3 silencing, and aggregation
Sapp, E.; Boudi, A.; Iwanowicz, A.; Belgrad, J.; Miller, R.; Robertson, R.; O'Reilly, D.; Yamada, K.; Deng, Y.; Joni, M.; Li, X.; Kegel-Gleason, K.; Khvorova, A.; Reiner, A.; Aronin, N.; DiFiglia, M.
10.1101/2024.12.31.630891 — neuroscience — Posted on 2025-06-05
60 Endothelin B receptor inhibition rescues aging-dependent neuronal regenerative decline
Feng, R.; Rosen, S. F.; Ansari, I.; John, S.; Thomsen, M. B.; Avraham, O.; Geoffroy, C. G.; Cavalli, V.
10.1101/2024.06.08.597928 — neuroscience — Posted on 2025-06-05
61 Inferring cell dynamics in stress-induced neuroblastoma cell cultures
Hafiichuk, K.; Hamis, S.; Karlsson, J.; Gisselsson, D.; Chattopadhyay, S.
10.1101/2025.03.17.643601 — cancer biology — Posted on 2025-06-05
62 Making AI accessible for forensic DNA profile analysis
de Wit, A. K. J. G.; Wagenaar, C. D.; Janssen, N. A.; Hoegen, B.; van de Wetering, J.; Hoofs, H.; Ariëns, S.; Benschop, C. C.; Ypma, R. J.
10.1101/2025.06.02.656996 — bioinformatics — Posted on 2025-06-05
65 Deep learning from videography as a tool for measuring E. coli infection in poultry
Scheidwasser, N.; Poulsen, L. L.; Leow, P. R.; Khurana, M. P.; Iglesias-Carrasco, M.; Laydon, D. J.; Donnelly, C. A.; Bojesen, A. M.; Bhatt, S.; Duchene, D. A.
10.1101/2024.11.20.624075 — animal behavior and cognition — Posted on 2025-06-05
67 Shola Sky Islands Survey 2025
P, S. M.; L, R. R.; K, S. E.; K, V. C.
10.1101/2025.05.29.656751 — ecology — Posted on 2025-06-05
68 Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity
Lee, H.; Jaquish, A.; Fernandes, S.; Zhao, B.; Elitz, A.; Cook, K.; Trovillion, S.; Arias, N. M. B.; Han, S.; Goodwin, S.; Russell, N.; Zacharias, A. L.; Brugmann, S. A.; Whitsett, J. A.; Sinner, D. I.; Sun, X. I.; Swarr, D. T.; Zacharias, W. J.
10.1101/2025.06.02.657302 — developmental biology — Posted on 2025-06-05
73 Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimers disease
Marongiu, R.; Platholi, J.; Park, L.; Yu, F.; Sommer, G.; Woods, C.; Milner, T. A.; Glass, M. J.
10.1101/2025.03.14.643317 — neuroscience — Posted on 2025-06-05
74 Leveraging autophagy and pyrimidine metabolism to target pancreatic cancer
Dufresne, S.; Kuna, R. S.; Wong, K.; Komarla, A.; Rock, A.; Rosada-Encarnacion, J.; Shen, C.; Mondal, P.; Parham, L. R.; Layng, F. I.; Peck, K. L.; Fowler, A.; Lowy, A. M.; Engle, D.; Tiriac, H.; Shaw, R.; Cosford, N.; Metallo, C.; Towers, C. G.
10.1101/2025.05.29.656904 — cancer biology — Posted on 2025-06-05
79 An Evaluation of the Tumor Microenvironment through CALR,IL1R1,IFNB1,and IFNG to Assess Prognosis and Immunotherapy Response in Bladder Cancer Patients
Lilong, L.; Zhenghao, L.; Lei, F.; Zhipeng, Y.; Junyi, H.; Yaxin, H.; Yang, L.; Yuhong, D.; Yingchun, K.; Ke, C.; Yi, H.; Zheng, L.
10.1101/2024.01.24.577030 — immunology — Posted on 2025-06-05
81 A spatial transcriptomic atlas of acute neonatal lung injury across development and disease severity
Mallapragada, S.; Lyu, R.; Williams-Katek, A. L.; Fischer, B. K.; Vannan, A.; Hadad, N.; Mee, E. D.; Shirazi, S. P.; Jetter, C. S.; Negretti, N. M.; Hilgendorff, A.; Eldredge, L. C.; Deutsch, G. H.; McCarthy, D. J.; Kropski, J. A.; Sucre, J. M. S.; Banovich, N. E.
10.1101/2025.06.02.656433 — genomics — Posted on 2025-06-05
83 Chronic benzodiazepine treatment triggers gephyrin scaffold destabilization and GABAAR subsynaptic reorganization
Chapman, C. A.; Povysheva, N.; Tarr, T. B.; Nuwer, J. L.; Meriney, S. D.; Johnson, J. W.; Jacob, T. C.
10.1101/2025.06.02.653073 — neuroscience — Posted on 2025-06-05
87 Oxytocin release modulates acute neuroinflammation and improves brain development after pediatric traumatic brain injury
Knoop, M.; Trak, E.; Possovre, M.-L.; Van de Looij, Y.; Schirmbeck, G.; Ceyzeriat, K.; Pitetti, J.-L.; Farias Sanches, E.; Musardo, S.; Millet, P.; Tsartsalis, S.; Tournier, B. B.; Bellone, C.; Sizonenko, S. V.; Jacquens, A.; Baud, O.
10.1101/2025.06.02.652172 — neuroscience — Posted on 2025-06-05
90 LOSS OF ARGINASE 2 DISRUPTS STRIATUM-SPECIFIC POLYAMINE HOMEOSTASIS
Nalepa, M.; Basheer, O.; Radkiewicz, M.; Skowronska, K.; Skweres, A.; Owczarek, A.; Dalka, A.; Hilgier, W.; Zielinska, M.; Samborowska, E.; Wegrzynowicz, M.
10.1101/2025.06.02.657391 — neuroscience — Posted on 2025-06-05
92 iPSC-derived skeletal muscle spheroids for Duchenne Muscular Dystrophy modeling
Esposito, J.; Leite, F. d. S.; Barbosa, I. N.; Martins, T. M. d. M.; Olberg, G. G. d. O.; Tanoury, Z. A.; Telles-Silva, K. A.; Pardo, M. C. d. S.; Jazedje, T.; Bortolin, R. H.; Hirata, M. H.; Pourquie, O.; Zatz, M.
10.1101/2025.06.05.657880 — cell biology — Posted on 2025-06-05
100 Prediction, Syntax and Semantic Grounding in the Brain and Large Language Models
Koelbl, N.; Rampp, S.; Kaltenhaeuser, M.; Tziridis, K.; Maier, A.; Kinfe, T.; Chavarriaga, R.; Krauss, P.; Schilling, A.
10.1101/2025.06.05.658007 — neuroscience — Posted on 2025-06-05
106 An ultrasensitive spatial tissue proteomics workflow exceeding 100 proteomes per day
Klingeberg, M.; Krisp, C.; Fritzsche, S.; Schallenberg, S.; Hornburg, D.; Coscia, F.
10.1101/2025.06.02.657389 — systems biology — Posted on 2025-06-05
107 Contrastive Learning-Enhanced Drug Metabolite Prediction Drives the Discovery of an Orally Bioavailable RSK4 Inhibitor for Esophageal Cancer
He, H.; Zhang, M.; Yang, X.; He, S.; Shi, X.; Hu, F.; Liu, C.; Zhang, X.; Chen, N.; Zhu, X.; Zhang, L.; Ye, T.; Zhang, R.; Yang, Y.; Wang, R.; Zhao, Z.; Chen, Z.; Qian, X.; Li, H.; Wang, Z.; Zhang, K.; Liu, K.; Li, S.
10.1101/2025.06.02.657523 — cancer biology — Posted on 2025-06-05
108 Hepatocyte expression of fetal insulin receptor isoform contributes to the promotion of liver cancer through non-cell autonomous mechanisms
Leandre, F.; Iddir, A.; Godart, C.; Lagoutte, I.; Caldiero, A.; Souid, S.; Pinto, S.; Augustin, J.; Bou Malham, V.; Alves, A.; Aubry, R.; Imbeaud, S.; Zucman-Rossi, J.; Colnot, S.; Gougelet, A.; Desbois-Mouthon, C.
10.1101/2025.06.02.655477 — cancer biology — Posted on 2025-06-05
110 Supervised Deep Learning for Efficient Cryo-EM Image Alignment in Drug Discovery with cryoPARES
Sanchez-Garcia, R.; Berndt, A.; Apelbaum, A.; Reeks, J.; Williams, P. A.; Poelking, C.; Deane, C.; Saur, M.
10.1101/2025.03.04.641536 — bioinformatics — Posted on 2025-06-05
111 Characterization of Sex-Based Differences in Integrin-Mediated Endothelial Cel Adhesion to Bioactive Hydrogels
Nkansah, A.; Budhwani, A.; Grammer, N.; Ang, N.; Fairley, A.; Salazar, S. P.; Anand, A.; Yedalla, A. C.; Seidlits, S.; Allen, J.; Cosgriff-Hernandez, E.
10.1101/2025.06.02.656802 — bioengineering — Posted on 2025-06-05
112 Precise MRI-Histology Coregistration of Paraffin-Embedded Tissue with Blockface Imaging
Wang, Y.; Ho, W.; Huszar, I. N.; DiGiacomo, P.; Taghavi, H. M.; Tao, L.; Choi, M.; Nguyen, N.; Leventis, S.; Camarillo, D. B.; Schlomer, P.; Axer, M.; Shao, W.; Rusu, M.; Cobos, I.; Nirschl, J.; Georgiadis, M.; Zeineh, M.
10.1101/2025.06.02.657335 — bioengineering — Posted on 2025-06-05
113 Leech Speciation and Detection of Hirudin Gene among the Leech Population in Asejire Oyo State, Nigeria
Olajide, T. H.; Ajileye, A. O.; Bamikole, O. J.; Olufeagba, M.-d. B.; Adedeji, B. A.; Ademola, S. A.; Amodu, O. k.
10.1101/2025.06.02.657427 — genetics — Posted on 2025-06-05
116 The Sphingosine-1-phosphate pathway is differentially activated in human gestational tissues.
Mbadhi, M. N.; Fujiwara, H.; Gill, R.; Mitchum, K. T.; Lin, C.; Raghuraman, N.; Frolova, A. I.
10.1101/2025.06.02.657487 — developmental biology — Posted on 2025-06-05
117 PRPF8-associated retinitis pigmentosa variant induces human neural retina-autonomous photoreceptor defects
Zimmann, F.; Banik, P.; Kubovciak, J.; Thakur, P. K.; Capek, M.; Kolar, M.; Hruba, E.; Dobrovolny, R.; Cvackova, Z.; Barta, T.; Stanek, D.
10.1101/2025.06.04.657822 — cell biology — Posted on 2025-06-05
121 A dendritic cell population responsible for transglutaminase 2-mediated gluten antigen presentation in celiac disease
Yang, F.-C.; Besser, H. A.; Chun, H. R.; Albertelli, M. A.; Fernandez-Becker, N. Q.; Jabri, B.; Khosla, C.
10.1101/2025.06.02.657527 — immunology — Posted on 2025-06-05
122 CD14 plays a critical role in pain and inflammation across multiple models of post-traumatic osteoarthritis
Burt, K. G.; South, S. M.; Adamczyk, N. S.; Nguyen, V.; Ishihara, S.; Zhou, C.; Sharp, K. L.; Kim, S. Y.; Rapp, A. E.; Hu, B.; Murphy, L. A.; Hung, L.-Y.; Herbert, D.; Baker, J.; Mauck, R. L.; Griffin, T. M.; Malfait, A.-M.; Miller, R. E.; Scanzello, C. R.
10.1101/2025.06.02.657478 — immunology — Posted on 2025-06-05
123 Replaying germinal center evolution on a quantified affinity landscape
DeWitt, W. S. S.; Vora, A. A.; Araki, T.; Galloway, J. G.; Alkutkar, T.; Bortolatto, J.; Castro, T. B.; Dumm, W.; Jennings-Schaffer, C.; Jia, T.; Mesin, L.; Ozorowski, G.; Pae, J.; Ralph, D. K.; Bloom, J. D.; Nourmohammad, A.; Song, Y. S.; Ward, A.; Starr, T. N.; Matsen, F. A.; Victora, G. D.
10.1101/2025.06.02.656870 — immunology — Posted on 2025-06-05
124 A High-Resolution Atlas of the Brain Predicts Lineage and Birth Order Underly Neuronal Identity.
Allen, A. M.; Neville, M. C.; Nojima, T.; Alejevski, F.; Agarwal, D.; Sims, D.; Goodwin, S. F.
10.1101/2025.06.04.657818 — neuroscience — Posted on 2025-06-05
126 Primary tumor microbiomes predict distant metastasis of colorectal cancer
Parajuli, B.; Midya, V.; Kiddle, R.; De Jager, N.; Eggers, S.; Spakowicz, D.; Hoyd, R.; Salhia, B.; Chan, C. H.; Churchman, M.; Rounbehler, R. J.; Yao, S.; Rutkowski, M. R.; Tarhini, A. A.; Mudaranthakam, D. P.; Masood, A.; Bocklage, T. J.; Lentz, R. W.; Hatoum, H.; Ilozumba, M. N.; Hardikar, S.; Ulrich, C. M.; Round, J. L.; Riedlinger, G.; Shriver, C. D.; Bosch, D. E.
10.1101/2025.06.02.654060 — cancer biology — Posted on 2025-06-05
127 Biologically-informed machine learning identifies a new clinically-actionable bladder cancer subgroup characterised by NRF2 overactivity
Ungureanu, V. V.; Gawne, R. T.; Baker, S. C.; Eriksson, P.; Halliday, D. M.; Smith, S. L.; Southgate, J.; Mason, A. S.
10.1101/2025.06.03.657659 — cancer biology — Posted on 2025-06-05
128 Association of GADD45A and favorable outcome in hormone positive breast cancer
Lin, C.-Y.; Liu, C.-Y.; Chao, T.-C.; Huang, C.-C.; Tsai, Y.-F.; Tseng, L.-M.; Lai, J.-I.
10.1101/2025.06.02.657315 — cancer biology — Posted on 2025-06-05
130 Macrophage-derived reactive oxygen species promote Salmonella aggresome formation contributing to bacterial antibiotic persistence
Chen, X.; Fang, K.; Li, B.; Li, Y.; Ke, Y.; Ke, W.; Tian, T.; Zhao, Y.; Wang, L.; Geng, J.; Leake, M. C.; Bai, F. C.
10.1101/2025.06.03.657582 — biophysics — Posted on 2025-06-05
134 TCRanalyzer: A user-friendly tool for comprehensive analysis of T-cell diversity, dynamics and potential antigen targets
Seifert, N.; Reinke, S.; Kurz, N. S.; Demmer, J. A.; Kornrumpf, K.; Beissbarth, T.; Klapper, W.; Altenbuchinger, M.
10.1101/2025.05.09.652820 — bioinformatics — Posted on 2025-06-05
137 Mechanical force-mediated cellular crosstalk maintains the integrity of the lung gas exchange niche
Shen, C.; Morley, M. P.; Zhao, G.; Jones, D. L.; Schaefer, S. E.; Planer, J. D.; Chembazhi, U. V.; Kim, M.; Ying, Y.; Zhou, S.; Li, S.; Hallquist, H.; Lange, A.; Basil, M. C.; Morrisey, E. E.
10.1101/2025.06.04.657878 — cell biology — Posted on 2025-06-05
138 Caveolin-1 dependent regulation of cell-matrix interphase in 3D collagen gels.
Mazumdar, D.; Kataria, S.; Panda, G. P.; Kulkarni, A.; Patil, S. P. V.; Dash, M.; Balasubramanian, N.
10.1101/2025.06.04.657900 — cell biology — Posted on 2025-06-05
140 TGF-β serves as a critical signaling determinant of liver progenitor cell fate and function
Tong, C.; Lin, T.; Wang, H.; La Torre, C. D.; Liu, H.; Shao, C.; Hammad, S.; Liebe, R.; Ebert, M. P.; Ding, H.; Dooley, S.; Weng, H.-L.
10.1101/2025.06.04.657336 — cell biology — Posted on 2025-06-05
141 Senescent mast cells contribute to the progression of benign prostatic hyperplasia via SCF/c-KIT mediated endothelial-mesenchymal transition
Jing, Y.; Li, L.; Guo, W.; Cao, T.; Tang, J.; Zhou, D.; Yao, C.; Xu, J.; Liu, Y.; Feng, C.; Shi, Y.; Wang, M.; Chao, W.; Liao, H.; He, J.; Qin, L.; Luan, J.; Wang, X.; Cui, D.; Zhu, Y.; Ruan, Y.; Xia, S.; Han, B.
10.1101/2025.06.02.657200 — cell biology — Posted on 2025-06-05
146 Receptor-enriched analysis of functional connectivity (REACT) for understanding cannabinoid neuropsychopharmacology
Shatalina, E.; Ertl, N.; Petrilli, K.; Ofori, S.; Borisova, A.; Mokrysz, C.; Curran, V.; Lawn, W.; Freeman, T. P.; Howes, O.; Wall, M. B.
10.1101/2025.06.02.657387 — neuroscience — Posted on 2025-06-05
147 Linking offline learning mechanisms to anxiety traits
Yu, Q.; Luo, Y.; Dolan, R. J.; Ou, J.; Huang, C.; Wang, H.; Xiao, Z.; Nour, M.; Liu, Y.
10.1101/2023.06.21.546031 — neuroscience — Posted on 2025-06-05
148 Network-based Near-Scalp Personalized Brain Stimulation Targets
Kong, R.; Xue, A.; Ooi, L. Q. R.; Asplund, C.; Tan, X. W.; Goh, S. E.; Lee, J. J.; Koh, J. Z. J.; Tan, R. S. Y.; Singh, H. K. G.; Tan, T. W. K.; Webler, R. D.; Fox, M. D.; Siddiqi, S. H.; Tor, P.-C.; Yeo, B. T. T.
10.1101/2025.05.15.654391 — neuroscience — Posted on 2025-06-05
149 Remodeling of purinergic signaling in the paraventricular hypothalamus promotes hyperphagic obesity and insulin resistance
Liu, Y.; Bondarenko, A.; Zhang, H.; Luan, P.; Zhang, Q.; Wang, B.; Najam, S. S.; Liang, X.; Syed, A. A. S.; Lin, D.; Huang, S.; Konovalov, R.; Konopka, W.; Zhang, Z.; Zhang, Y.; Wu, S.; Jing, M.; Vinnikov, I. A.
10.1101/2024.07.02.601503 — neuroscience — Posted on 2025-06-05
150 OPM quantum sensors enhance non-invasive neuroimaging performance
Brickwedde, M.; Anders, P.; Krueger, P.; Sander, T.; Uhlhaas, P.
10.1101/2025.05.30.657044 — neuroscience — Posted on 2025-06-05
151 Prognostic significance of Ki-67, BAX, Caspase-3, and VEGF expression in feline intestinal lymphoma
Faraldo, N. C.; Rosenfeld, A. d. F. S.; Brombatti, K. G.; Amorim, R. L.; Battaglia, S. T. H.; Sobral, R. A.; Fonseca Alves, C. E.
10.1101/2025.06.01.657294 — pathology — Posted on 2025-06-05
154 Depth-resolved fiber photometry of amyloid plaque signals in freely behaving Alzheimer's disease mice
Byron, N.; McAlinden, N.; Pisano, F.; Pisanello, M.; Ferreira, J.; Montinaro, C.; Mathieson, K.; De Vittorio, M.; Pisanello, F.; Sakata, S.
10.1101/2025.04.08.647900 — neuroscience — Posted on 2025-06-05
155 Col6 deficiency in a zebrafish model of Bethlem myopathy leads to dysfunction of the muscle dihydropyridine receptor
Idoux, R.; Exbrayat-Heritier, C.; Shivaraman, S.; Jaque-Fernandez, F.; Ducret, A.; Berthier, C.; Jacquemond, V.; Sohm, F.; bretaud, s.; Ruggiero, F.; ALLARD, B.
10.1101/2025.06.02.657388 — pathology — Posted on 2025-06-04
157 The mutational dynamics of the Arabidopsis centromeres
Dong, X.; Jiao, W.-B.; Campoy, J. A.; Rabanal, F. A.; Ton, J.; Smith, L. M.; Weigel, D.; Schneeberger, K.
10.1101/2025.06.02.657473 — genomics — Posted on 2025-06-04
160 Persistent cortical excitatory neuron dysregulation in adult Chd8 haploinsufficient mice.
Canales, C. P.; Lozano, S.; Frost, N. A.; Cichewicz, K.; Amaral, W.; Seban, N.; Fenton, E.; Wade, A.; Chu, N.; Smith, E.; Ardekani, C.; Frank, S.; Bennett, J.; Lavenex, P.; Kopley-Smith, A.; Rahbarian, D.; Corea, M.; Perla, D.; Davis, L.; Zhu, J.; Ortiz, R.; Beauregard, P.; Moyer, C.; Baker, J.; Sun, J.; Ma, B.; Lu, J.; Sohal, V. S.; Amaral, D. G.; Zuo, Y.; Nord, A. S.
10.1101/2025.06.04.657776 — genomics — Posted on 2025-06-04
161 Single-nucleus epigenomic dysregulation unmasks genetic risk-associated neurodegenerative glia states
Han, X.; Zhang, T.; Lee, C.-Y.; Ravi, A.; Spina, S.; Li, A. N.; Grinberg, L. T.; Seeley, W. W.; Huckins, L. M.; Raj, T.; Brennand, K. J.; Rexach, J. E.
10.1101/2025.06.02.657512 — genomics — Posted on 2025-06-04
162 The Insertion of an ATTTC Repeat in an Alu Element Hyperactivates a Primate-Specific Neurodevelopmental Enhancer in Spinocerebellar Ataxia Type 37
Loureiro, J. R.; Castro, A. F.; Figueiredo, A. S.; Eufrasio, A.; Dhingra, A.; Galhardo, M.; Marcelino, H.; Rodrigues, C.; Sampaio, P.; Azevedo, M. M.; Sousa, M.; Doria, S.; Rizzu, P.; Heutink, P.; Bessa, J.; Silveira, I.
10.1101/2025.06.03.657633 — genetics — Posted on 2025-06-04
164 Malaria shaped human spatial organisation for the last 74 thousand years
Colucci, M.; Leonardi, M.; Blinkhorn, J.; Irish, S. R.; Padilla-Iglesias, C.; Kaboth-Bar, S.; Gosling, W. D.; Snow, R. W.; Manica, A.; Scerri, E. M. L.
10.1101/2025.06.04.657870 — evolutionary biology — Posted on 2025-06-04
165 Sp Transcription Factors Establish the Signaling Environment in the Neuromesodermal Progenitor Niche During Axial Elongation
Chalamalasetty, R. B.; Tran, H.; Kelly, R.; Kuo, S.; Kennedy, M. W.; Lee, M.; Thomas, S.; Mandalos, N.; Koparde, V.; Pereira Lobo, F.; Yamaguchi, T. P.
10.1101/2025.06.03.657492 — developmental biology — Posted on 2025-06-04
166 Cell fate specification during respiratory development requires ARID1A-containing canonical BAF complex activity
Lee, H.; Jaquish, A.; Fernandes, S.; Zhao, B.; Elitz, A.; Cook, K.; Trovillion, S.; Arias, N. M. B.; Han, S.; Goodwin, S.; Russell, N.; Zacharias, A. L.; Brugmann, S. A.; Whitsett, J. A.; Sinner, D. I.; Sun, X. I.; Swarr, D. T.; Zacharias, W. J.
10.1101/2025.06.02.657302 — developmental biology — Posted on 2025-06-04
167 Human microglia in brain assembloids display region-specific diversity and respond to hyperexcitable neurons carrying SCN2A mutation
Wu, J.; Chen, X.; Zhang, J.; Wettschurack, K. W.; Robinson, M. J.; Li, W.; Zhao, Y.; Yoo, Y.-E.; Deming, B. A.; Abeyaratna, A. D.; Que, Z.; Du, D.; Tegtmeyer, M. T.; Yuan, C.; Skarnes, W. C.; Rochet, J.-C.; Wu, L.-J.; Yang, Y.
10.1101/2025.06.04.657874 — neuroscience — Posted on 2025-06-04
172 Artemether and Euphorbia Factor L9 suppress kynurenine production through distinct effects on Tryptophan metabolism.
Capatina, A. L. L.; Czechowski, T.; Plunkett-Jones, C.; Tonon, T.; Kourtzelis, I.; Lichman, B. R.; Brackenbury, W. J.; Graham, I. A.; Lagos, D.
10.1101/2025.06.02.657401 — cancer biology — Posted on 2025-06-04
177 Functional insights into the photoactive yellow protein family from homologs, multidomain proteins and inferred pyp operons
Dohmen, R.; Hoogerwerf, G.; Dohmen, A. J.; Neal, M. L.; Bradley, C.; Huffman, C.; Teeman, S. M.; Hampton, S. F.; Powell, S.; Gunn, Z.; Hoff, W. D.
10.1101/2025.06.04.657921 — microbiology — Posted on 2025-06-04
178 Desiccation-induced DNA damage facilitates drug resistance in Mycobacterium tuberculosis
Brown, C. D.; Lee, B. M.; Liu, H.; Wu, A.; Tellez, A. V.; Zou, H.; Singh, P.; Saito, K.; Mishra, S.; Brown, M.; Saleh, A.; Odjourian, N. M.; Cristaldo, M.; Gan, M.; Liu, Q.; Gengenbacher, M.; Darst, S. A.; Campbell, E. A.; Nathan, C. F.; Rhee, K. Y.
10.1101/2025.06.04.657859 — microbiology — Posted on 2025-06-04
180 Cell-free genome-wide transcriptomics through machine learning optimization
Wagner, L.; HOANG, A.; RUE, O.; Delumeau, O.; Loux, V.; Faulon, J.-L.; Jules, M.; Borkowski, O.
10.1101/2025.06.04.657821 — synthetic biology — Posted on 2025-06-04
181 Plasmodium falciparum subverts neutrophil function via host miR-451a loaded extracellular vesicles driving bacterial superinfection susceptibility
Babatunde, K. A.; Ngara, M.; Martinez Murillo, P.; Subramanian, B.; Hopke, A.; Lucchesi, S.; Novedrati, M.; Montesi, G.; Santoro, F.; Hagemann-Jensen, M.; Sandberg, R.; Filgueira, L.; Irimia, D.; Walch, M.; Mantel, P.-Y.
10.1101/2025.06.02.657463 — immunology — Posted on 2025-06-04
182 Inter-individual variability in immune responses to AAV-mediated ocular gene delivery across species impedes reliable immunomonitoring profile
REN, D.; CHAUVEAU, G.; VENDOMELE, J.; CABON, E.; PINEIRO, A.; VIGNAL-CLERMONT, C.; SALIBA, H.; RONZITTI, G.; GALY, A.; DALKARA, D.; PULMAN, J.; AIL, D.; FISSON, S.
10.1101/2025.06.02.656863 — immunology — Posted on 2025-06-04
184 Platelet concentrate-derived extracellular vesicles promote adult hippocampal neurogenesis
NyamErdene, A.; Thao Ngoc Le, N.; Nebie, O.; Faivre, E.; Delila, L.; Chou, M. L.; Lowe, J.; Bantubungi, K.; Buee, L.; Walker, T.; Blum, D.; Burnouf, T.
10.1101/2025.04.29.651163 — neuroscience — Posted on 2025-06-04
186 Towards Unmanned Proteomics Data Generation: A Fully Automated Sample-to-Data System for Proteomic Experiments
Wang, D.; Chen, W.; Xie, L.; Xu, Y.; Huang, C.; Liu, Y.; Wang, X.; Huang, X.; Zhang, K.; Pan, M.; Wang, S.; Qin, B.; Yang, Y.; Yang, J.; Tang, L.; Tian, R.; He, F.
10.1101/2025.06.02.656978 — biochemistry — Posted on 2025-06-04
189 Structural insights into context-specific inhibition of bacterial translation by macrolides
Syroegin, E. A.; Aleksandrova, E. V.; Kruglov, A. A.; Paranjpe, M. N.; Svetlov, M. S.; Polikanov, Y. S.
10.1101/2025.06.03.657637 — molecular biology — Posted on 2025-06-04
190 Human cytomegalovirus-encoded G protein-coupled receptor (GPCR), UL78, regulates viral reactivation
Osanyinlusi, S. A.; Baruah, V.; Groves, I. J.; Kulp, K. H.; Krishna, B. A.; O'Connor, C. M.
10.1101/2025.06.04.657869 — microbiology — Posted on 2025-06-04
192 Gut microbiota of Brazilian Melipona stingless bees: dominant members and their localization in different gut regions
Tristao Santini, A.; Cerqueira, A. E. S.; Moran, N. A.; Resende, H. C.; Santana, W. C.; de Paula, S. O.; da Silva, C. C.
10.1101/2025.06.03.657762 — microbiology — Posted on 2025-06-04
193 Identification of a Broadly Acting Inhibitor of the Alphavirus Non-Structural Protein 2 Helicase
Sears, J. D.; Ojha, D.; Taft-Benz, S.; Sylvester, P. A.; Streblow, Z.; Gramm, A. J.; Drobish, A. M.; Ramalingam, B. M.; Hossain, M. A.; Talbot, K. M.; Sanders, W.; Chang, C.-K.; Law, I.; Martinez, S. A.; Burdick, J. E.; Wiltshire, R.; Saba, N. A.; Poplarski, J. H.; Counago, R. M.; Brown, P. J.; Anand, G. S.; Morrison, T. E.; Arnold, J. J.; Cameron, C. E.; Streblow, D. N.; Willson, T. M.; Heise, M. T.; Moorman, N. J.
10.1101/2025.06.03.657755 — microbiology — Posted on 2025-06-04
195 Common and distinct neural correlates of social interaction perception and theory of mind
Miao, Z.; Jung, H.; Kragel, P. A.; Bo, K.; Sadil, P.; Lindquist, M. A.; Wager, T. D.
10.1101/2024.12.19.628993 — neuroscience — Posted on 2025-06-04
197 An artificial nervous system for communication between wearable and implantable therapeutics
Ghanim, R.; Lee, Y. J.; Byun, G.; Jackson, J.; Ding, J. Z.; Feller, E.; Kim, E.; Aygun, D.; Kaushik, A.; Cig, A.; Park, J.; Healy, S.; Cunin, C. E.; Gumyusenge, A.; Yeo, W. H.; Abramson, A.
10.1101/2025.06.04.657863 — bioengineering — Posted on 2025-06-04
198 Perilipin 4 repetitive region forms amyloid fibrils promoted by a genetic expansion found in myopathy patients
Choufani, C.; Fuggetta, N.; Sabbagh, B.; Moulin, C.; Franckhauser, C.; Lyonnais, S.; Perme, T.; Arteni, A.-A.; Pagnotta, S.; Rouquier, S.; Ruggieri, A.; Bousset, L.; Copic, A.
10.1101/2025.06.03.657256 — biochemistry — Posted on 2025-06-04
201 PKP2 orchestrates OXPHOS expression in cardiomyocytes via a PGC1α-dependent mechanism
Han, S. J.; den Berg, D.; de Ruiter, H.; Tsui, H.; Kyriakopoulou, E.; Koopmans, T.; Perini, I.; Monshouwer-Kloots, J.; van Kampen, S. J.; te Riele, A. S. J. M.; Kelters, I. R.; Gianoli, M.; Burgering, B. M. T.; van Rooij, E.
10.1101/2025.06.02.656790 — molecular biology — Posted on 2025-06-04
202 Clinical Trypanosoma cruzi isolates share a common antigen repertoire that is absent from culture adapted strains
Hakim, J. M. C.; Gutierrez Guarnizo, S. A.; Duran, A.; Malaga-Machacha, E.; Duque, C.; Singer, L.; Colanzi, R.; Sherbuk, J. E.; Gilman, R.; Bern, C.; Messenger, L. A.; Mugnier, M. R.; Working Group on Chagas Disease in Bolivia and Peru,
10.1101/2025.06.04.657671 — microbiology — Posted on 2025-06-04
205 R-Spondin Mimetic, SZN-043, Induced Proliferation and Expression of Wnt Target Genes, Two Impaired Features in Human Alcohol-Associated Liver Disease
Fisher, T.; Patel, M.; Deshmukh, S.; Shah, D.; Lu, C.; Newman, M.; Ye, J.; Fletcher, R.; Vanhove, G. F.; Tibbitts, J.; Li, Y.; Skill, N. J.; Yang, Z.; Liangpunsakul, S.; Baribault, H.
10.1101/2024.11.19.624277 — pathology — Posted on 2025-06-04
209 The evolution of separate sexes in waterhemp is associated with surprising chromosomal diversity and complexity
Kreiner, J. M.; Montgomery, J. S.; Todesco, M.; Bercovich, N.; Gong, Y.; Elphinstone, C.; Tranel, P. J.; Rieseberg, L. H.; Wright, S. I.
10.1101/2024.09.17.613486 — evolutionary biology — Posted on 2025-06-04
212 Efficient Generation of Expandable Dorsal Forebrain Neural Rosette Stem Cell Lines
Frazier, S. E. D.; de Lichtenberg, K. H.; Jaberi, E.; Bertelsen, C.; Jensen, S. M.; Wrona, A.; Christophersen, N. S.; Kristensen, M.; Villaescusa, J. C.
10.1101/2025.05.27.656305 — neuroscience — Posted on 2025-06-04
213 Population structure of Phytophthora infestans collected from potatoes in Guatemala and Honduras
Izarra, M. L.; Perez, W. G.; Vasquez, E. F.; Perez, G. E.; Gamboa, S.; Andrade-Piedra, J.; Flores, B.; Montejo, L.; Sanders, A.; Kreuze, J. F.
10.1101/2025.05.28.656702 — pathology — Posted on 2025-06-04
214 Reconciling the effects of PMS2 in different repeat expansion disease models supports a common therapeutic strategy
Jimenez, D. A.; Miller, C. J.; Walker, A.; Anupindi, K.; Hayward, B. E.; Lorenzi, H. A.; Usdin, K.; Zhao, X.
10.1101/2024.08.13.607839 — genetics — Posted on 2025-06-04
217 3D Quantification of Viral Transduction Efficiency in Living Human Retinal Organoids
Rogler, T. S.; Salbaum, K. A.; Brinkop, A. T.; Sonntag, S. M.; James, R.; Shelton, E. R.; Thielen, A.; Rose, R.; Babutzka, S.; Klopstock, T.; Michalakis, S.; Serwane, F.
10.1101/2024.03.06.583795 — neuroscience — Posted on 2025-06-04
219 The intratumoral microbiome is negatively associated with malignancy in dermatofibrosarcoma protuberans
Jian, X.; Liu, Z.; Zhang, J.; Li, Y.; Xie, L.; Zhao, G.; Li, B.; Li, J.; Peng, C.; Wan, M.; Chen, X.
10.1101/2025.06.02.657449 — microbiology — Posted on 2025-06-04
220 The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues
Zhu, B.; Fung, K.; Feng, H. H.; Beatty, J. A.; Hill, F.; Tse, A. C.; Brackman, C. J.; Sit, T. H.; Poujade, A.; Gaide, N.; Ducatez, M.; Foucras, G.; Peiris, M.; Ti, S.-C.; Nicholls, J. M.; Yen, H.-L.
10.1101/2025.06.02.657404 — microbiology — Posted on 2025-06-04
221 Evolutionary trajectories determine the feasibility of collateral sensitivity based antibiotic treatment strategies in critical bacterial pathogens
Brandis, G.; Chauhan, V.; Enkvist, L.; Chukhareva, Y.; Damell, C.; Cruz Davila, E.; Islam, T. M.; Melander, G.; Paulsson, E.; Sundell, A.; Zweifel, E.; Knöppel, A.
10.1101/2025.06.03.657621 — microbiology — Posted on 2025-06-04
224 eIF4G2-Mediated Translation Initiation of Histone Modifiers Is Essential for Intestinal Stem Cell Maintenance and Differentiation
Kunitomi, H.; Khaine, A. M.; Jamee, R.; Arreola, V.; Lancero, M.; Raychaudhuri, A.; Perli, S. D.; Sato, Y.; Iwasaki, M.; Ruivo, P. R.; Tomoda, K.; Mito, M.; Shichino, Y.; Iwasaki, S.; Yamanaka, S.
10.1101/2025.05.19.652834 — cell biology — Posted on 2025-06-04
225 Z-Form Stabilization By The Zα Domain Of Adar1p150 Has Subtle Effects On A-To-I Editing
Nichols, P. J.; Riemondy, K. A.; Krall, J. B.; Ramos, J.; Goering, R.; Henen, M. A.; Taliaferro, J. M.; Vogeli, B.; Vicens, Q.
10.1101/2025.06.02.657529 — cell biology — Posted on 2025-06-04
226 Dendritic computation for rule-based flexible categorization
Zhang, Y.; Liu, Y.; Hu, Y.; Zhang, Z.; Du, J.; Cui, L.; Liu, Q.; Zhong, L.; Xin, Y.; Chai, R.; Deng, L.; Pan, J.; Schiller, J.; Xu, N.-l.
10.1101/2025.06.03.657766 — neuroscience — Posted on 2025-06-04
228 MRAP2 modifies signaling and oligomerization state of the melanocortin-4 receptor
Sohail, I.; Laurin, S.-A.; Kleinau, G.; Chunilal, V.; Morton, A.; Brenlla-Lopez, A.; Kagiali, Z. C. U.; Tello, J. A.; Blouin, M.-J.; Beck-Sickinger, A. G.; Lohse, M. J.; Scheerer, P.; Bouvier, M.; McCormick, P.; Annibale, P.; Biebermann, H.
10.1101/2024.04.09.588099 — pharmacology and toxicology — Posted on 2025-06-04
231 A heterogeneous pharmaco-transcriptomic landscape induced by targeting a single oncogenic kinase
Giglio, R. M.; Hou, N.; Wyatt, A.; Hong, J.; Shi, L.; Vaikunthan, M.; Fuchs, H.; Nima, J. P.; Malinowski, S. W.; Ligon, K. L.; McFaline-Figueroa, J. R.; Yosef, N.; Azizi, E.; McFaline-Figueroa, J. L.
10.1101/2024.04.08.587960 — genomics — Posted on 2025-06-04
234 Dendritic computation for rule-based flexible categorization
Zhang, Y.; Hu, Y.; Zhang, Z.; Du, J.; Cui, L.; Liu, Q.; Zhong, L.; Xin, Y.; Chai, R.; Deng, L.; Pan, J.; Schiller, J.; Xu, N.-l.
10.1101/2025.06.03.657766 — neuroscience — Posted on 2025-06-04
239 Molecular Phenotypic Plasticity Informs Possible Adaptive Change of Triple-Negative Breast Cancer Cells In Vivo
Iftehimul, M.; Muganda, P. M.; Newman, R. H.; Rorie, C. J.; Harrison, S. H.; Hossain, M. T.; Thomas, M. D.; Graves, J. L.; Saha, D.
10.1101/2025.05.31.657204 — cancer biology — Posted on 2025-06-04
242 Investigating the consequences of the mating system for drug resistance evolution in C. elegans
Trubenova, B.; Hellinga, J.; Krücken, J.; von Samson-Himmelstjerna, G.; Schulenburg, H.; Regoes, R. R.
10.1101/2024.11.07.620884 — evolutionary biology — Posted on 2025-06-04
243 Long-term surveillance suggests multiple hybridization events by nuclear reassortment and accelerated intercontinental spread of wheat yellow rust
Hovmoeller, M. S.; Thach, T.; Algaba, J. R.; Hansen, J. G.; Meyer, M.; Hodson, D.; Nazari, K.; Park, R. R.; Tamm, R.; Moeller, M.; Schwessinger, B.; Rathjen, J. P.; Silva, P.; Riella, V.; Justesen, A. F.
10.1101/2025.05.22.655633 — evolutionary biology — Posted on 2025-06-04
245 Genetic interaction library screening with a next-generation dual guide CRISPR system
Burgold, T.; Karakoc, E.; Goncalves, E.; Barrio-Hernandez, I.; Dwane, L.; Silva, R. O.; Souster, E.; Sharma, M.; Beck, A.; Koh, G.; Zalmas, L.-P.; Garnett, M.; Bassett, A. R.
10.1101/2024.03.28.587052 — molecular biology — Posted on 2025-06-04
249 Kinetic-model-guided engineering of multiple S. cerevisiae strains improves p-coumaric acid production
Narayanan, B.; Jiang, W.; Wang, S.; Saez-Saez, J.; Weilandt, D. R.; Masid, M.; Hesselberg-Thomsen, V.; Borodina, I.; Hatzimanikatis, V.; Miskovic, L.
10.1101/2024.12.15.628543 — systems biology — Posted on 2025-06-04
250 Defense-Suppressive Fragments of RIN4 generated by AvrRpt2 Participate in NDR1-dependent Activation of RPS2
Afzal, A. J.; Alam, M.; Huang, J.; Agha, M.; Da Cunha, L.; Iqbal Rai, M.; Tahir, J.; Jamroze, A.; Jones, J. D.; Mackey, D.
10.1101/2025.06.02.656948 — plant biology — Posted on 2025-06-04
251 Megakaryocytes assemble a three-dimensional cage of extracellular matrix that controls their maturation and anchoring to the vascular niche
Masson, C.; Scandola, C.; Rinckel, J.-Y.; Proamer, F.; Janus-Bell, E.; Batool, F.; OSMANI, N.; GOETZ, J. G.; Mallo, L.; Brouard, N.; Leon, C.; Bornert, A.; Poincloux, R.; Destaing, O.; Mansson, A.; QIAN, H.; Lehmann, M.; Eckly, A.
10.1101/2024.09.30.615769 — physiology — Posted on 2025-06-04
253 Microbial hydrocarbon degradation potential of the Baltic Sea ecosystem
Serrana, J. M.; Dessirier, B.; Nascimento, F. J. A.; Broman, E.; Posselt, M.
10.1101/2025.06.02.657333 — ecology — Posted on 2025-06-04
255 ONE-STEP tagging: a versatile method for rapid site-specific integration by simultaneous reagent delivery
Migliori, V.; Bruntraeger, M.; Gyulev, I.; Lichou, F.; Burgold, T.; Gitterman, D.; Iwama, S.; Trinh, A.; Washer, S. J.; Jones, C.; Trynka, G.; Bassett, A. R.
10.1101/2024.08.29.610246 — molecular biology — Posted on 2025-06-04
256 cGAS-STING dependent type I IFN protects against Leptospira interrogans renal colonization in mice.
Gupta, S.; Matsunaga, J.; Ratitong, B.; Ismaeel, S.; Valadares, D.; West, P.; Kerur, N.; Stehlik, C.; Dorfleutner, A.; Dagvadorj, J.; Coburn, J.; Wolf, A.; Cassel, S.; Haake, D.; Sutterwala, F. S.
10.1101/2025.06.02.657349 — immunology — Posted on 2025-06-04
257 Memory by a thousand rules: Automated discovery of multi-type plasticity rules reveals variety and degeneracy at the heart of learning.
Confavreux, B.; Harrington, Z.; Kania, M.; Ramesh, P.; Krouglova, A. N.; Bozelos, P. A.; Macke, J. H.; Saxe, A. M.; Goncalves, P. J.; Vogels, T. P.
10.1101/2025.05.28.656584 — neuroscience — Posted on 2025-06-04
260 Pasta, an age-shift transcriptomic clock, maps the chemical and genetic determinants of aging and rejuvenation
Salignon, J.; Tsiokou, M.; Marques, P.; Rodriguez-Diaz, E.; Ang, H.; Pietrocola, F.; Riedel, C. G.
10.1101/2025.06.04.657785 — bioinformatics — Posted on 2025-06-04
261 REnformer, a single-cell ATAC-seq predicting model to investigate open chromatin sites
Riva, S. G.; Sanders, E.; Wilson, T.; Stranieri, N.; Gur, R.; Baxter, M.; Hughes, J. R.
10.1101/2025.06.04.657786 — bioinformatics — Posted on 2025-06-04
264 Multiscale radiobiological assessment of laser-driven very high energy electrons versus conventional electrons
Giaccaglia, C.; Bayart, E.; Dubail, M.; Varma, C.; Heinrich, S.; Gautier, J.; Tafzi, A.; Kononenko, O.; Goddet, J.-p.; Lamarre-Jouenne, I.; Fouillade, C.; Flacco, A.
10.1101/2025.05.27.656200 — cell biology — Posted on 2025-06-04
265 JADE family proteins regulate proteasome abundance and activity
Ebert, L. K.; Bargfrede, S.; Bohl, K.; Cohen, H.; Mueller, R.-U.; Benzing, T.; Schermer, B.
10.1101/2021.10.01.462752 — cell biology — Posted on 2025-06-04
267 Cytokine expression profile in the human brain of older adults
Godoy, J. B.; Vialle, R. A.; dos Santos, L.; Raittz, R. T.; Wang, Y.; Menon, V.; De Jager, P.; Schneider, J. A.; Tasaki, S.; Bennett, D. A.; Guizelini, D.; Lopes, K.
10.1101/2025.06.02.657444 — molecular biology — Posted on 2025-06-04
268 Focused ultrasound neuromodulation of mediodorsal thalamus disrupts decision flexibility during reward learning
Mackenzie, G.; Gilmour, W.; Yang, S. S.; Suveges, S.; MacFarlane, J.; Kanodia, A.; Manfield, J.; Khan, S.; Osman-Farah, J.; Marcerolo, A.; Steele, D.; Gilbertson, T.
10.1101/2025.06.03.657634 — neuroscience — Posted on 2025-06-04
270 Dendritic computation for rule-based flexible categorization
Xu, N.-l.; Zhang, Y.; Hu, Y.; Zhang, Z.; Du, J.; Cui, L.; Liu, Q.; Zhong, L.; Xin, Y.; Chai, R.; Deng, L.; Pan, J.; Schiller, J.
10.1101/2025.06.03.657766 — neuroscience — Posted on 2025-06-04
272 PANDA: A simple and affordable chamber system for measuring the whole-plant net CO2 flux
Schuler, P.; Li, Y.; Pittet, P.; Favre, P.; Li, M.-H.; Zhang, Y.-L.; Grossiord, C.
10.1101/2025.06.02.657330 — plant biology — Posted on 2025-06-04
273 Loss of UFMylation supports prostate cancer metastasis and rewires cell metabolism towards hexosamine biosynthesis
Bozal Basterra, L.; Salazar Palacio, M. C.; Ferreira Campos, A. M.; Demicco, M.; Schmidt, D. R.; Sobczak, K.; Ereno-Orbea, J.; Altea Manzano, P.; Miranda Villanueva, A.; Martinez La Osa, B.; Garcia-Longarte, S.; Ponce Rodriguez, M.; Mendizabal, I.; Carlevaris Lopez, O.; Astobiza, I.; Martin Martin, N.; Zabala-Letona, A.; Talamillo, A.; Fernandez Garcia, J.; Azkargorta, M.; Iloro, I.; Barrio, R.; Elortza, F.; Fendt, S. M.; Vander Heiden, M. G.; Jimenez Barbero, J.; D. Sutherland, J.; Carracedo, A.
10.1101/2025.06.02.657324 — cancer biology — Posted on 2025-06-04
274 Data-driven symbolic regression reveals microbial growth laws
Sun, T. A.; Kiciatovas, D.; Aapalampi, I.-K.; Kuosmanen, T.; Hiltunen, T.; Mustonen, V.
10.1101/2025.06.02.657040 — ecology — Posted on 2025-06-04
275 A new resource of clonal pluripotent human stem cell lines exhibiting inter- and intra-embryo consistency and variability
Strawbridge, S. E.; Bates, L. E.; Ross, C.; Jones, K. A.; Azami, T.; Lohoff, T.; Paramor, M.; Murray, V.; Cidral, A. L.; Clarke, J.; Rostovskaya, M.; Guo, G.; Nichols, J.
10.1101/2025.06.02.657331 — developmental biology — Posted on 2025-06-04
277 Towards Unified Neural Decoding with Brain Functional Network Modeling
Wu, D.; Bu, L.; Jia, Y.; Cao, L.; Li, S.; Zhou, Y.; Fan, S.; Ren, W.; Wu, D.; Wang, K.; Zhang, Y.; Ma, Y.; Yang, J.; Mohamad, S.
10.1101/2025.06.02.657011 — neuroscience — Posted on 2025-06-04
279 NF-κB is a Central Regulator of Hypoxia-Induced Gene Expression
Shakir, D.; Batie, M.; Kwok, C.-S.; Cook, S. J.; Kenneth, N. S.; Rocha, S.
10.1101/2025.01.08.631917 — molecular biology — Posted on 2025-06-04
280 RNAi epimutations conferring antifungal drug resistance are inheritable
Perez-Arques, C.; Navarro-Mendoza, M. I.; Xu, Z.; Walther, G.; Heitman, J.
10.1101/2024.10.15.618540 — microbiology — Posted on 2025-06-04
283 Single-cell morphological profiling reveals insights into programmed cell death
Frey, B.; Holmberg, D.; Bystrom, P.; Bergman, E.; Georgiev, P.; Johansson, M. M.; Hennig, P.; Rietdijk, J.; Rosen, D.; Carreras-Puigvert, J.; Spjuth, O.
10.1101/2025.01.15.633042 — bioinformatics — Posted on 2025-06-04
284 Population-scale inheritance analysis of 858,635 individuals reveals North Sea migration from the Middle Ages to the Industrial Revolution
Zhang, X.; Holm, P.; Scally, A.; Banasik, K.; Mortensen, L. H.; Fitzgerald, T. W.; Westergaard, D.; Chmura, P. J.; Ostrowski, S. R.; Sorensen, E.; Pedersen, O. B. V.; Schwinn, M.; Erikstrup, C.; Bruun, M. T.; Jensen, B. A.; Ullum, H.; Mikkelsen, C.; Hansen, T. F.; DBDS Genetic Consortium, ; Stefansson, K.; Brunak, S.; Birney, E.
10.1101/2025.03.19.643007 — genetics — Posted on 2025-06-04
286 PROTRIDER: Protein abundance outlier detection from mass spectrometry-based proteomics data with a conditional autoencoder
Klaproth-Andrade, D.; Scheller, I.; Tsitsiridis, G.; Loipfinger, S.; Mertes, C.; Smirnov, D.; Prokisch, H.; Yepez, V.; Gagneur, J.
10.1101/2025.02.01.636024 — bioinformatics — Posted on 2025-06-04
288 Aedes albopictus is rapidly invading its climatic niche in France: wider implications for biting nuisance and arbovirus control in Western Europe
Radici, A.; Hammami, P.; Cannet, A.; L'Ambert, G.; Lacour, G.; Fournet, F.; Garros, C.; Guis, H.; Fontenille, D.; Caminade, C.
10.1101/2025.02.14.638223 — ecology — Posted on 2025-06-04
291 OPM quantum sensors enhance non-invasive neuroimaging performance
Brickwedde, M.; Anders, P.; Krueger, P.; Sander, T.; Uhlhaas, P.
10.1101/2025.05.30.657044 — neuroscience — Posted on 2025-06-04
292 Valence of sensory stimulation as a key feature for subcortical entrainment: Insights from human intracranial EEG
Hoyer, R. S.; Bernier, M.-F.; Martineau, L.; Lessard Bonaventure, P.; Labelle, C.; Borderie, A.; Blanchette, I.; Blumenthal, A.; Laureys, S.; Albouy, P.
10.1101/2025.01.03.631218 — neuroscience — Posted on 2025-06-04
295 Butterfly wing iridescence is regulated by araucan, a direct target of Optix and Spalt
Chatterjee, M.; Finet, C.; Siegel, K. J.; Loh, L. S.; Delgado, S.; McDonald, J. M. C.; Markenscoff-Papadimitriou, E.; Monteiro, A.; Reed, R. D.
10.1101/2023.11.21.568172 — genetics — Posted on 2025-06-03
298 Human brain network control of creativity
Rabinovich, R.; Cowan, R. L.; Libowitz, M.; Davis, T.; Rahimpour, S.; Beaty, R.; Bartoli, E.; Sheth, S.; Smith, E. H.; Shofty, B.
10.1101/2025.06.03.657648 — neuroscience — Posted on 2025-06-03
303 Enzyme Activity Regulates Substrate Diffusion by Modulating Viscosity in Crowded Milieu
Bevilacqua, A.; Maciel, M. R.; Sullivan, M. V.; Pascarelli, S.; Dindo, M.; Shen, A. Q.; Laurino, P.
10.1101/2024.09.28.615560 — biochemistry — Posted on 2025-06-03
305 The Balance between B55α and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells
Zach, R.; Annis, M.; Martin-Guerrero, S. M.; Alatawi, A.; Chia, K. H.; Meredith, M.; Osborn, K.; Peter, N.; Pearce, W.; Booth, J.; Rajasekaran, M.; Dias, S.; Coleman-Evans, L.; Foster, W. R.; Harper, J. A.; Herbert, A. D.; Tighe, C.; Reuillon, T.; West, R.; Busby, O.; Burdova, K.; Crepin, D.; Ortoll, S.; Vaeteewoottacharn, K.; Dejsuphong, D.; Spencer, J.; Patel, H.; Le Grand, D.; Hunt, T. A.; Andrews, D. M.; Yamano, H.; Cutillas, P. R.; Oliver, A. W.; Ward, S. E.; Hochegger, H.
10.1101/2025.06.02.657035 — cell biology — Posted on 2025-06-03
307 Orderly mitosis shapes interphase genome organization
Guin, K.; Keikhosravi, A.; Chari, R.; Pegoraro, G.; Misteli, T.
10.1101/2025.06.03.657645 — cell biology — Posted on 2025-06-03
308 Lost in communication: How Mueller glia cells fail to maintain retinal integrity in USH1C retinal organoids
Wenck, N.; Zorin, M.; Wang, Q.; Kroell, S.; Hay, K.; Rickert, C.; Mendez-Lago, M.; Karunanithi, S.; Athanasiou, D.; Ziaka, K.; De Angeli, P.; Stingl, K.; Kohl, S.; Cheetham, M. E.; Mittmann, T.; Nagel-Wolfrum, K.
10.1101/2025.06.03.657614 — cell biology — Posted on 2025-06-03
309 Pharmacological targeting of SOS1-RAS interaction triggers pancreatic β-cell proliferation and sustainably reverses diabetic hyperglycemia
Papadimitropoulou, A.; Charalampous, C.; Kogionou, P.; Reinhardt, D.; Sonntag, J.; Gavalas, A.; Hofmann, M. H.; Erlmann, P.; Franti, M.; Doerr, J.; Klein, T.; Willis, G. R.; Serafimidis, I.
10.1101/2025.06.03.657628 — cell biology — Posted on 2025-06-03
310 Translation-specific disruption of Col1a1 expression in multiple models of Spinal Muscular Atrophy can be rescued by Risdiplam.
Sharma, G.; Paganin, M.; Huang, N.; Perenthaler, E.; Signoria, I.; Faller, K.; Maniscalco, F.; Perrucci, C.; Donzel, D.; Chaytow, H.; Basso, M.; Lauria, F.; Kothary, R.; Van Der Pol, L.; Claus, P.; Groen, E. J.; Gillingwater, T. H.; Viero, G.
10.1101/2025.06.03.657600 — molecular biology — Posted on 2025-06-03
311 Multi-Omic Profiling Identifies Conserved Metabolic Pathways Critical for SARS-CoV-2 Variants Infection
Farley, S. E.; Kyle, J. E.; Jahn, H.; Bramer, L.; Piehowski, P.; Shepmoes, A.; Kaiser, B. L.; Williams, S. M.; Eder, J. G.; Schultz, C.; Tafesse, F.
10.1101/2025.06.02.657371 — systems biology — Posted on 2025-06-03
312 Dietary zinc restriction induces irreversible allodynia in adult mice
Matias, D. O.; Santos, B. L. R.; Martins, A. F.; Souza, L. P.; Miranda-Alves, L.; Cardoso, L. E. M.; Miranda, A. L. P.; Lima, L. M. T.
10.1101/2025.06.02.657430 — biochemistry — Posted on 2025-06-03
313 CTx001 for geographic atrophy: a gene therapy expressing soluble, truncated complement receptor 1 (mini-CR1)
Rathi, S.; Didangelos, A.; Pisarenka, S.; Green, R.; Emery-billcliff, P.; Patel, N.; Whalley, P.; Zamira, P.; Tilakaratna, V.; Szula, E.; Hasan, R.; Munye, M.; Unwin, R.; Bishop, P.; Keefe, D.; Clark, S. J.
10.1101/2025.06.03.657557 — biochemistry — Posted on 2025-06-03
316 Linker Histone H1.5 Contributes to Centromere Integrity in Human Cells
Saha, A.; Bui, M.; Melters, D. P.; Ganesan, A. K.; Baek, S.; Bentahar, R. S.; Dalal, Y.
10.1101/2025.06.03.657682 — biochemistry — Posted on 2025-06-03
318 An Antibody Cocktail-Based Immunoaffinity-LC-MS Method Enabled Ultra-Sensitive and Robust Quantification of Circulating Proinsulin Proteoforms and C-peptide
Shen, Q.; Cao, W.; Zhang, M.; Lin, T.; Shi, T.; nierves, l.; Evans-Molina, C.; Peterman, s.; boeser, c.; Sims, E. K.; Monaco, G.; QIAN, W.-J.; Qu, J.
10.1101/2025.06.02.657397 — biochemistry — Posted on 2025-06-03
321 Structure of the energy converting methyltransferase (Mtr) of Methanosarcina mazei in complex with an oxygen-stress responsive small protein
Reif-Trauttmansdorff, T.; Herdering, E.; Bohn, S.; Pascoa, T.; Kahnt, J.; Zimmer, E.; Kumar, A.; Schmitz, R. A.; Schuller, J. M.
10.1101/2025.06.02.657420 — biochemistry — Posted on 2025-06-03
325 Genomic factors contributing to the resilience of Salmonella enterica on ready-to-eat muskmelon
Esteban Cuesta, I.; Führer, L.; Porwollik, S.; Chu, W.; Fiddaman, S. R.; Sah, I.; McClelland, M.; Guldimann, C.
10.1101/2025.06.02.657348 — genomics — Posted on 2025-06-03
327 An intergenerational lipid memory of the social environment in C. elegans
Wilhelm, T.; Chen, W.-W.; Wenzel, A.; Tang, W.; Cicerone, M. T.; Lehner, B.
10.1101/2025.06.03.657568 — genetics — Posted on 2025-06-03
328 In vitro plasticity between ureteric epithelial and distal nephron identity and maturity is controlled by extracellular signals.
Kairath, P.; Er, P. X.; Wilson, S. B.; Ghobrial, I. T.; Vanslambrouck, J. M.; Chen, Y.-H.; Pruett-Miller, S. M.; Jain, S.; Little, M. H.
10.1101/2025.06.03.657609 — developmental biology — Posted on 2025-06-03
329 Single cell multiomic analysis of the impact of Delta-9-tetrahydrocannabinol on HIV infected CD4 T cells
Ashokkumar, M.; Ge, R. Y.; Cooper-Volkheimer, A.; Margolis, D.; Li, Q.; Jiang, Y.; Murdoch, D. M.; Browne, E. P.
10.1101/2025.06.02.657468 — molecular biology — Posted on 2025-06-03
330 Zika virus reprograms the host tRNA epitranscriptome to adapt translation to A-ending codon bias
ELDIN, P.; BERNARD, E.; VAGBO, C.; GEORGE, L.; AJIRO, M.; HAGIWARA, M.; SLUPPHAUG, G.; BRIANT, L.
10.1101/2025.06.03.657606 — microbiology — Posted on 2025-06-03
331 A conserved glycan motif overcomes antigenic variation inducing broadly reactive antibodies against the zoonotic pathogen Streptococcus suis
Shi, Y.; Widmalm, G.; Sorieul, C.; Roodsant, T. J.; Rush, J. S.; Korotkova, N.; Jacobs, A. A. C.; Spaninks, M.; Grommen, R.; Dominguez-Medina, C. C.; Schimmel, I. M.; van der Wel, N. N.; Kenner, C. W.; Heiss, C.; Azadi, P.; Tan, L.; Codee, J. D. C.; Stegeman, A.; Schultsz, C.; Benedictus, L.; van Sorge, N. M.
10.1101/2025.06.02.656523 — microbiology — Posted on 2025-06-03
333 Global Landscape of Human Kinase Motifs in Viral Proteomes
Alba, K.; Winters, D. M.; Makanani, S. K.; Kaushal, P.; Delgado, Y.; Ashley, I. A.; Sharma, S.; Blanc, S. F.; Kim, E.; Yaron, T.; Johnson, J. L.; Selby, J.; Hur, M.; Ni, J.; Nguyen, J.; Brent, M. H.; Yip, E.; Kassem, A.; Wohlschlegel, J.; Fregoso, O. I.; Wu, T.-T.; Li, M. M.; Bouhaddou, M.
10.1101/2025.06.02.657064 — microbiology — Posted on 2025-06-03
334 Global proteomic analysis of Cryptococcus neoformans clinical strains reveals significant differences between latent and lethal infection
Betancourt, J. J.; McAlister, J. A.; Perez, J. M.; Meya, D. B.; Thomas, S. N.; Geddes-McAlister, J.; Nielsen, K.
10.1101/2025.06.03.657666 — microbiology — Posted on 2025-06-03
337 The Role of SARS-CoV-2 Nucleocapsid Protein Persistence in Inducing Chronic Type I Interferon and Mitochondrial Dysfunction.
Koenig, A.; Quasem, M.; Zink, B.; Abdulla-Zoda, D.; Karunanidhi, P.; Sienko, K.; Geier, C.; Jayaraman, V.; Malik, R.; Ahmed, K.; Shanley, P. F.; Koenig, I. A.
10.1101/2025.06.02.657400 — immunology — Posted on 2025-06-03
338 A histidine switch regulates pH-dependent filament formation by the caspase-9 CARD
Rawal, S.; Kolaric, Đesika; Bohn, S.; Kolb, D.; Pavkov-Keller, T.; Pritisanac, I.; Madl, T.; Desfosses, A.; Alderson, T. R.
10.1101/2025.06.02.657148 — biophysics — Posted on 2025-06-03
339 Thermally activated irreversible homogenization of G-quadruplexes in an ALS/FTD-associated nucleotide expansion
Ross, D.; Lewis, O.; McLean, O.; Bhanot, S.; Donahue, S.; Baker, R.; Dias, R.; Eagerton, D.; Mohanty, V.; Mohanty, B. K.
10.1101/2025.06.02.657482 — biophysics — Posted on 2025-06-03
342 Adhesive implant interfaces prevent fibrosis by disrupting mechanobiological feedback
Jafari, M.; Aymon, B.; Hong, Y.; Shakiba, D.; Genin, G. M.; Zhao, X.; Alisafaei, F.
10.1101/2025.06.01.657311 — biophysics — Posted on 2025-06-03
344 Self-Assembled siRNA-Gold Supraclusters Detected at the Single-Molecule Level in the NIR-II Window
Ayed, Z.; Martin Munoz, B.; Vandekerckhove, C. I.; Faure, V.; Ali, S. N. S.; Coll, J.-L.; Cognet, L.; Le Guevel, X.
10.1101/2025.06.01.657319 — bioengineering — Posted on 2025-06-03
349 Evolution of genotypic and phenotypic diversity in multispecies biofilms
Amador, C. I.; Moskovitz, S. Z.; Maccario, L.; Herschend, J.; Kramer, I. S.; Jeckel, H.; Cooper, V. S.; Drescher, K.; Neu, T. R.; Burmolle, M.; Roder, H. L.
10.1101/2023.10.08.561388 — microbiology — Posted on 2025-06-03
353 NeuID, a novel neuron-specific lncRNA, resolved a key epigenetic mechanisms linking gene silencing to Alzheimer's disease
Pradhan, R.; Petrovic, Z.; Sakib, M. S.; Schroeder, S.; Krueger, D. M.; Pena, T.; Diniz, E.; Burkhardt, S.; Schuetz, A.-L.; Grz_dzielewska, I.; Toischer, K.; Stein, T. D.; Blusztajn, J. K.; Delalle, I.; Radulovic, J.; Sananbenesi, F.; Fischer, A.
10.1101/2025.06.01.657217 — neuroscience — Posted on 2025-06-03
356 Novel mouse model reveals neurodevelopmental origin of PMM2-CDG brain pathology
Edmondson, A. C.; Budhraja, R.; Xia, Z.; Melendez-Perez, A.; Cai, C.; Radenkovic, S.; Collins, A.; Shiplett, E.; Hill, S. F.; Somarowthu, A.; Dam, J.; Pai, L.-L.; Santi, M.; Kim, S.; He, M.; Goldberg, E.; Kozicz, T.; Morava, E.; Pandey, A.; Zhou, Z.
10.1101/2025.06.01.657261 — neuroscience — Posted on 2025-06-03
360 Evolving resistance patterns in Tetranychus urticae and Bemisia tabaci in Greece
Kampouraki, A.; Ilias, A.; Papapostolou, K.-M.; Malliaraki, S.; Pyrgianakis, I.; Karakosta, E.; Vontas, J.; Tsagkarakou, A.; Mavridis, K.
10.1101/2025.05.31.656940 — pharmacology and toxicology — Posted on 2025-06-03
361 Lack of synergy between AR targeted therapies and PARP inhibitors in homologous recombination-proficient prostate cancer
Traphagen, N. A.; Wheeler, E.; Li, R.; Lu, F.; Ahmed, B.; Tewari, A. K.; Balk, S. P.; Nelson, P. S.; Corey, E.; Long, H.; D'Andrea, A. D.; Qiu, X.; Brown, M.
10.1101/2025.06.02.657429 — cancer biology — Posted on 2025-06-03
362 The mutational landscape defines the proteome and spatial organization of tumor, stroma and immune cells in ovarian cancer
Dabke, K.; Gull, N.; Kreimer, S.; Peng, P.-C.; Diaz, M.; Cheikh, B. B.; Dhawan, A.; Evans, K.; Ng, N.; Yuan, X.; Rimel, B.; Li, A. J.; Karlan, B. Y.; Knott, S. V.; Gayther, S. A.; Parker, S. J.; Jones, M. R.
10.1101/2025.06.01.655822 — cancer biology — Posted on 2025-06-03
363 Targeting HMGA1-driven leukemic transformation in myeloproliferative neoplasms with pacritinib
Yang, C.; Li, Y.; Chen, K.; Tang, X.; Zhang, Q.; Qin, W.; Fu, J.; Zeng, Y.; Ma, X.; Zheng, W.; Huang, Z.; Zhang, W.; Tang, G.; Guan, M.; Wu, Z.
10.1101/2025.06.01.657170 — cancer biology — Posted on 2025-06-03
365 Non-Invasive Mechanical-Functional Analysis of Individual Liver Mitochondria by Atomic Force Microscopy
Zorikova, E. O.; Chourasia, S.; Rosenhek-Goldian, I.; Cohen, S. R.; Nesterov, S. V.; Gross, A.
10.1101/2025.06.01.657242 — biophysics — Posted on 2025-06-03
370 Desmoplakin Haploinsufficiency Underlies Cell-Cell Adhesion Failure in DSP Cardiomyopathy and is Rescued by Transcriptional Activation
Smith, E. D.; Jin, K.; Ferguson, B.; Tsan, Y.-C.; DePalma, S. J.; Meisner, J. K.; Renberg, A.; Bedi, K.; Friedline, S.; Margulies, K. B.; Baker, B. M.; Helms, A. S.
10.1101/2025.06.01.657304 — genetics — Posted on 2025-06-03
372 A method for creating custom 3D-printed molds to facilitate zebrafish imaging studies, including of cardiac development.
Miller, J. C.; Koirala, P.; Argote de la Torre, M. F.; Farsi, M.; Lieberth, J.; Shrestha, R.; Bloomekatz, J.
10.1101/2025.06.01.657246 — developmental biology — Posted on 2025-06-03
373 prdm1a drives a fate switch between hair cells of different mechanosensory organs
Sandler, J.; Tsai, Y.-Y.; Chen, S.; Sabin, L.; Lush, M.; Sur, A.; Ellis, E.; Tran, N. T. T.; Cook, M.; Scott, A. R.; Kniss, J. S.; Farrell, J. A.; Piotrowski, T.
10.1101/2025.06.01.657251 — developmental biology — Posted on 2025-06-03
376 Novel Adomaviruses Associated with Blotchy Bass Syndrome in Black Basses (Micropterus spp.)
Iwanowicz, L.; Raines, C.; Young, K.; Blazer, V.; Walsh, H.; Smith, G.; Holt, C.; Odenkirk, J.; Jones, T.; Hessenauer, J.-M.; Biggs, M.; Buck, C.; Greer, J.; Cornman, R. S.
10.1101/2025.06.01.657292 — microbiology — Posted on 2025-06-03
377 ACOD1 regulates microglial arginine metabolism and inflammatory responses
Karadima, E.; Yilmaz, C.; Sinha, A.; Fodelianaki, G.; Dimothyra, S.; Nirakis, N.; Traikov, S.; Zamboni, N.; Wielockx, B.; Verginis, P.; Peitzsch, M.; Chavakis, T.; Alexaki, V. I.
10.1101/2025.06.01.657243 — immunology — Posted on 2025-06-03
378 Diverse modes of T cell receptor sequence convergence define unique functional and cellular phenotypes
Schattgen, S.; Vegesana, K.; Hazelton, W. D.; Minervina, A.; Valkiers, S.; Slowikowski, K.; Smith, N. P.; MGH COVID-19 Team, ; Villani, A.-C.; Thomas, P. G.; Bradley, P.
10.1101/2025.05.31.657155 — immunology — Posted on 2025-06-03
381 Direct Binding of FGFR3 Autoantibodies to Sensory Neurons Drives Hyperexcitability and Mechanical Hypersensitivity
Salih, L. Y.; Dumaire, N. L.; Vest, E.; Alkhateeb, H.; Moritz, C. P.; Tholance, Y.; Camdessanche, J.-P.; Antoine, J.-c.; Honnorat, J.; Kafaie, J.; francois-Moutal, L.; Moutal, A.
10.1101/2025.06.01.657230 — neuroscience — Posted on 2025-06-03
383 A characterization of mouse retinal ganglion cell types labeled with AAV tools
Son, S.; Beaudoin, D. L.; Hassan, A. R.; Akpo, M. S.; Ichinose, T.; Garrett, A. M.
10.1101/2025.06.02.657062 — neuroscience — Posted on 2025-06-03
388 Resistance to Atrial Fibrillation Domestication and Mitochondrial Dysfunction in Sheep: a potential key role of the TCA Cycle and mitochondrial redox state
Caluori, G.; Nattel, S.; Pinson, B.; Naud, P.; Beauvoit, B.; Claverol, S.; Vaillant, F.; Charron, S.; Guilloteau, F.; Loyer, V.; Constantin, M.; Popa, M.; Belykh, A.; Haeberlin, A.; Ploux, S.; Mahamat, H. A.; Dubois, R.; Guillot, B.; Krisai, P.; Kamakura, T.; Bernus, O.; Jais, P.; Dos Santos, P.; Pasdois, P.
10.1101/2025.06.01.657249 — pathology — Posted on 2025-06-03
389 Multimodal imaging reveals a lysosomal drug reservoir that drives heterogeneous distribution of PARP inhibitors
Moncayo, C. R.; Restuadi, R.; Zhang, G.; Marks, D.; Ortega-Prieto, P.; Doherty, E.; Lambie, N.; Whilding, C.; Andrew, I.; Montoya, A.; Patel, B.; Pennycook, B. R.; Wu, V.; Takats, Z.; Matthews, N.; Young, G. R.; Shliaha, P.; Game, L.; Lenhard, B.; McNeish, I.; Fotopoulou, C.; Barr, A. R.; Cunnea, P.; Hall, Z.; Fets, L.
10.1101/2025.05.31.656628 — cancer biology — Posted on 2025-06-03
394 Competing Subclones and Fitness Diversity Shape Tumor Evolution Across Cancer Types
Chen, H.; Shu, J.; Mudappathi, R.; Li, E.; Wang, P.; Bergsagel, L.; Yang, P.; Sun, Z.; Zhao, L.; Shi, C.; Townsend, J. P.; Maley, C.; Liu, L.
10.1101/2025.05.31.657191 — bioinformatics — Posted on 2025-06-03
396 DeepLC introduces transfer learning for accurate LC retention time prediction and adaptation to substantially different modifications and setups
Bouwmeester, R.; Nameni, A.; Declercq, A.; Devreese, R.; Velghe, K.; Gorshkov, V.; Penanes, P. A.; Kjeldsen, F.; Rompais, M.; CARAPITO, C.; Gabriels, R.; Martens, L.
10.1101/2025.06.01.657225 — bioinformatics — Posted on 2025-06-03
397 scVIVA: a probabilistic framework for representation of cells and their environments in spatial transcriptomics
Levy, N.; Ingelfinger, F.; Bakulin, A.; Cinnirella, G.; Boyeau, P.; Nadler, B.; Ergen, C.; Yosef, N.
10.1101/2025.06.01.657182 — bioinformatics — Posted on 2025-06-03
398 BifurcatoR: A Framework for Revealing Clinically Actionable Signal in Variance Masquerading as Noise
Madaj, Z. B.; Ding, M.; Khoo, C. K.; Tokarski, E.; Fagnocchi, L.; PERMUTE, ; Li, Z.; Riordan, J.; Pospisilik, J. A.; Nadeau, J.; Lary, C.; Triche, T. J.
10.1101/2025.06.01.657083 — bioinformatics — Posted on 2025-06-03
400 A Set of Novel Far-Red Fluorescent Proteins for Temporal Domain Multiplexing and Super-Resolution Imaging
Olumayowa, F.; Rong, Z.; Wang, R.; Papadaki, S.; Wang, X.; Cao, J.; Subach, F. V.; Koster, R. W.; Namikawa, K.; Piatkevich, K. D.
10.1101/2025.06.01.657196 — biochemistry — Posted on 2025-06-03
403 A Single-cell and Spatially Resolved Cell Atlas of Human Esophageal Squamous Cell Carcinoma
shi, y.; An, K.; Qi, Y.; Zhang, X.; Wang, Y.; Zhang, X.; Zhou, S.; Li, O.; Zhou, J.; Du, Y.; Hou, M.; Yang, Y.-G.; Kan, Q.; Tian, X.
10.1101/2025.06.01.657221 — genomics — Posted on 2025-06-03
405 Simulation-based spatially explicit close-kin mark-recapture
Patterson, G.; Goodfellow, C. K.; Ting, N.; Kern, A. D.; Ralph, P. L.
10.1101/2025.05.31.656892 — ecology — Posted on 2025-06-03
406 Transcription factors SP5 and SP8 drive primary cilia formation
Liang, Y.; Koche, R.; Chalamalasetty, R. B.; Stephen, D. N.; Kennedy, M. W.; Lao, Z.; Pang, Y.; Kuo, Y.-Y.; Lee, M.; Lobo, F. P.; Huang, X.; Hadjantonakis, A.-K.; Yamaguchi, T. P.; Anderson, K. V.; Joyner, A. L.
10.1101/2025.06.03.657415 — developmental biology — Posted on 2025-06-03
409 Structural basis of liver de-targeting and neuronal tropism of CNS-targeted AAV capsids
Brittain, T. J.; Jang, S.; Coughlin, G. M.; Barcelona, B. H.; Giriat, I.; Ristic, F.; Appling, N.; Chossis, C. P.; Shay, T. F.; Gradinaru, V.
10.1101/2025.06.02.655683 — molecular biology — Posted on 2025-06-03
410 Mobile genetic elements that shape microbial diversity and functions in thawing permafrost soils
Guo, J.; Aroney, S.; Dominguez-Huerta, G.; Smith, D.; Vik, D.; Ansah, C. O.; Pratama, A. A.; Solonenko, S.; Tian, F.; Howard-Varona, C.; Zhong, Z.; Fofana, A.; Smith, G.; Hodgkins, S. B.; Cronin, D.; EMERGE Field Teams 2010-2019, ; EMERGE Coordinators, ; Woodcroft, B. J.; Tyson, G. W.; Rich, V. I.; Sullivan, M. B.; Roux, S.; Bagby, S. C.
10.1101/2025.02.12.637893 — microbiology — Posted on 2025-06-03
411 Evaluating Best Practices for Isolating Pyrophilous Bacteria and Fungi from Burned Soil
Enright, D. J.; Veerabahu, A.; Quaal, R. J.; Vega, M.; Nguyen, A.; Grindeland, J.; Randolph, J. W. J.; Ordonez, M. E.; Glassman, S. I.
10.1101/2024.09.16.612975 — microbiology — Posted on 2025-06-03
412 Non-Physiological Potassium Concentrations in Commercial Culture Media Trigger Acute Epileptiform Activity in Human iPSC-Derived Neurons
Lyckenvik, T.; Izsak, J.; Arthursson, E.; Forsberg, M.; Johansson, K.; Zetterberg, H.; Axelsson, M.; Wasling, P.; Theiss, S.; Hanse, E.; Illes, S.
10.1101/2025.05.31.657142 — neuroscience — Posted on 2025-06-03
413 Social experience alters behaviors by reprogramming the Fruitless pathway and circadian state in Drosophila
Du, C.; Okuwa, S.; Jia, L.; Rozados Barreiro, M.; Scott, S.; Sotelo Fonseca, J. E.; Mabuchi, Y.; Appadoo, S.; Garcia, L.; Rohrbach, S.; Koruk, S.; Balkanli, E.; Lin, J.; Yapici, N.; Jones, C.; Volkan, P.
10.1101/2025.05.30.657129 — neuroscience — Posted on 2025-06-03
415 Antidepressants reactivate developmental plasticity through remodeling of extracellular matrix
Nguyen, P. T.; Sun, E.; Shi, Y.; Tamura, S.; Xiao, Y.; Lacefield, C.; Turi, G.; Hen, R.
10.1101/2025.01.03.631260 — neuroscience — Posted on 2025-06-03
417 Sleep loss suppresses the motivation to prepare for sleep
Freitag, N.; El-Tawil, K.; Crane, A.; Hilo, V.; Saad, G.; Eban-Rothschild, A.
10.1101/2025.06.02.657276 — neuroscience — Posted on 2025-06-03
419 Molecular Subtyping Based on Hippocampal Cryptic Exon Burden Reveals Proteome-wide Changes Associated with TDP-43 Pathology across the Spectrum of LATE and Alzheimer's Disease
Trautwig, A. N.; Shantaraman, A.; Chung, M.; Dammer, E. B.; Ping, L.; Duong, D. M.; Petrucelli, L.; Ward, M. E.; Glass, J. D.; Nelson, P. T.; Levey, A. I.; McEachin, Z. T.; Seyfried, N. T.
10.1101/2025.05.30.656396 — neuroscience — Posted on 2025-06-03
422 A Solid-Phase Extraction Capture (SPEC) workflow in nanoliter volumes for fast, robust and ultrasensitive proteomics
Heymann, T.; Oliinyk, D.; Henneberg, L.; Rodriguez, E.; Bardziukova, A.; Oeller, M.; Murgia, M.; Olsen, J. V.; Stoychev, S.; Bache, N.; Mann, M.
10.1101/2025.05.31.657165 — systems biology — Posted on 2025-06-03
423 Expanding salivary biomarker detection by creating a synthetic neuraminic acid sensor via chimeragenesis
Verzino, S. J.; Priyev, S. A.; Sanchez Estrada, V. A.; GholamianMoghaddam, A.; Crowley, G. X.; Rutkowski, A.; Lam, A. C.; Nazginov, E. S.; Kotemelo, P.; Bacelo, A.; Flannery, J. D.; Gavrilov, K.; Sukhram, D. T.; Vazquez, F. X.; Fernandez Juarez, J.
10.1101/2024.06.13.598939 — synthetic biology — Posted on 2025-06-03
426 Oxidative stress mediates cardiac electrophysiological injury in inhalation exposure to flavored vaping products.
Abou-Assali, O. J.; Reiser, M.; Chang, M.; Chidipi, B.; Asswaytte, R.; Zhang, Y.; Szekeres, C.; Calcul, L.; Noujaim, S. F.
10.1101/2025.05.31.657128 — physiology — Posted on 2025-06-03
427 Cryo-EM structure of DNA-unbound human MCM2-7 complex reveals new disease-relevant regulation
Liu, Y.; Yang, M.; Lu, P.; Gao, H.; He, M.; Wang, Y.; Qi, A.; Cao, T.; Zhang, Q.; Qi, S.; Shi, Y.; Yu, H.
10.1101/2025.05.31.656953 — biophysics — Posted on 2025-06-03
430 A parallelly distributed microscope and software system for scalable high-throughput multispectral 3D imaging
Jiang, H.; Walker, L. A.; Li, Y.; Duan, B.; Niu, X.; Hsieh, J.-C.; Cheng, M.-C.; Su, H.; Sheng, K.; Tang, J. P.; Athukorala, K.; Greene, S.; Pan, R.; Parlapalli, A.; Yin, P.; Cui, M.; Cai, D.
10.1101/2025.05.31.657163 — bioengineering — Posted on 2025-06-03
435 Clonal Expansion of Alveolar Fibroblast Progeny Drives Pulmonary Fibrosis
Molina, C.; Tsukui, T.; Khan, I.; Ren, X.; Qiu, W.; Matthay, M.; Wolters, P.; Sheppard, D.
10.1101/2025.05.31.657194 — cell biology — Posted on 2025-06-03
436 Sequence grammar and dynamics of subcellular translation revealed by APEX-Ribo-Seq
Tomuro, K.; Akaiwa, T.; Harada, A.; Kobayashi, K.; Shiina, N.; Kawaguchi, K.; Shichino, Y.; Iwasaki, S.
10.1101/2025.05.26.656194 — molecular biology — Posted on 2025-06-03
441 Modelling Glomerular Filtration using Multispectral Optoacoustic Tomography and a Novel Near-infrared Dye
Littlewood, J.; Harwood, R.; Vajpayee, S.; Perciaccante, R.; Trivino-Cepeda, K.; Sharkey, J.; Sardella, T.; Burton, N.; Taylor, A.; Wilm, B.; Bearon, R.; Murray, P.
10.1101/2025.05.31.657147 — physiology — Posted on 2025-06-03
442 Introduction of cytosine-5 DNA methylation sensitizes cells to oxidative damage
Krwawicz, J.; Sheeba, C. J.; Hains, K.; McMahon, T.; Zhang, Y.; Kriaucionis, S.; Sarkies, P.
10.1101/2024.09.13.612259 — molecular biology — Posted on 2025-06-03
443 Heat-off responses of epidermal cells sensitize Drosophila larvae to noxious inputs
Yoshino, J.; Chiu, A.; Morita, T.; Yin, C.; Tenedini, F. M.; Sokabe, T.; Emoto, K.; Parrish, J. Z.
10.1101/2025.05.30.656957 — neuroscience — Posted on 2025-06-03
444 A covalent recognition strategy enables conspecific mate identification
Jang, S. S.; Mandala, S.; Jiang, H.; Zhang, X.; Cole, P. A.; del Marmol, J. I.
10.1101/2025.05.30.657074 — neuroscience — Posted on 2025-06-03
445 Transforming descending input into motor output: An analysis of the Drosophila Male Adult Nerve Cord connectome
Cheong, H. S. J.; Eichler, K.; Stuerner, T.; Asinof, S. K.; Champion, A. S.; Marin, E. C.; Oram, T. B.; Sumathipala, M.; Venkatasubramanian, L.; Namiki, S.; Siwanowicz, I.; Costa, M.; Berg, S.; Janelia FlyEM Project Team, ; Jefferis, G. S. X. E.; Card, G. M.
10.1101/2023.06.07.543976 — neuroscience — Posted on 2025-06-03
447 Reflected Inline Detection in Epi Oblique Plane Microscopy
Prince, M. N. H.; Muthubharathi, B. C.; Herath, W.; Sain, N.; Rupam, M. R. I.; Bhat, A. Q.; Wani, A. R.; Syed, M. H.; Kim, T.-H.; Walker, M. C.; Ponomarova, O.; Chakraborty, T.
10.1101/2025.05.30.657110 — biophysics — Posted on 2025-06-03
449 Risk evaluation of newly emerging flu viruses based on genomic sequences and AI
Li, H.; Feng, Y.; Lu, C.; Fu, P.; Wang, X.; Yang, L.; Shu, Y.; Jiang, T.; Wang, D.; Peng, Y.
10.1101/2025.04.18.649608 — bioinformatics — Posted on 2025-06-03
450 Species interactions determine plasmid persistence in a 3-member bacterial community
Schaal, K. A.; Wang, Y.-J.; Nauta, J.; Pilosof, S. A.; De Domenico, M.; Hall, J. P.
10.1101/2025.05.31.657151 — ecology — Posted on 2025-06-03
451 Two birds with one stone: a novel potential antibiotic blocking IsdB-mediated heme extraction by Staphylococcus aureus with serendipitous hemoglobin left-shifting activity
Hijazi, S.; Marchesani, F.; Marchetti, M.; Buoli Comani, V.; Brear, P.; Campanini, B.; Ronda, L.; Faggiano, S.; Gianquinto, E.; Asgharpour Hassankiadeh, S.; Rolando, B.; Spyrakis, F.; Compari, C.; Lazzarato, L.; De Bei, O.; Frangipani, E.; Bettati, S.
10.1101/2025.05.29.656759 — microbiology — Posted on 2025-06-03
453 Multivariate pattern analysis reveals resting-state EEG biomarkers in fibromyalgia
Soldic, D.; Martin-Buro, M. C.; Lopez-Garcia, D.; del Pino, A. B.; Fernandes-Magalhaes, R.; Ferrera, D.; Pelaez, I.; Mercado Romero, F.
10.1101/2025.05.30.657056 — neuroscience — Posted on 2025-06-03
454 Normalization of Prefrontal Network Dynamics Prevents Cognitive Impairments After Developmental Insult
Khalife, M. R.; Jasinski, P.; Abed Rabbo, K.; Ouardouz, M.; Mahoney, J. M.; Scott, R.; Hernan, A.
10.1101/2025.05.30.657069 — neuroscience — Posted on 2025-06-03
455 Detection of astrocyte epigenetic memory in in vitro systems, experimental autoimmune encephalomyelitis and multiple sclerosis samples
Quintana, F. J.; Li, Z.; Faust Akl, C.; Lee, J.-H.; Piester, G.; Antel, J.; Rothhammer, V.; Wheeler, M. A.; Prat, A.; Clark, I. C.
10.1101/2025.05.30.657119 — neuroscience — Posted on 2025-06-03
456 Bright and Photostable Voltage Sensors Derived from mBaoJin
Zhang, H.; Zhou, S.; Kuzmicheva, T. P.; Subach, O. M.; Grimm, C.; Eom, M.; Baror-Sebban, S.; Adam, Y.; Yoon, Y.-G.; Emilliani, V.; Subach, F. V.; Piatkevich, K. D.
10.1101/2025.05.30.657123 — neuroscience — Posted on 2025-06-03
457 Structural and Mechanistic Insights into Symmetry Conversion in Plant GORK K+ Channel Regulation
Li, Q.-y.; Qin, L.; Tang, L.-h.; Zhang, C.-r.; Huang, S.; Wang, K.; Zhang, G.-h.; Hao, N.-j.; Xiao, Q.; Niu, T.-X.; Su, M.; Hedrich, R.; Chen, Y.-h.
10.1101/2024.12.17.628833 — plant biology — Posted on 2025-06-03
460 Adaptive motility enables neutrophils to rapidly navigate confined capillaries
Deygas, M.; Bernard, M.; Nivoit, P.; Barbier, L.; Wang, L.; Maurin, M.; Tejerina, E.; Jakuszeit, T.; Deslys, A.; Garcia-Gomez, M.; Baaziz, O.; Garbay, S.; Terriac, E.; Attia, R.; Dumenil, G.; Piel, M.; VARGAS, P.
10.1101/2025.01.08.631737 — cell biology — Posted on 2025-06-03
461 Plasmodium falciparum egress disrupts endothelial junctions and activates JAK-STAT signaling in a microvascular 3D blood-brain barrier model
Piatti, L.; Batzilla, A.; Nakaki, F.; Fleckenstein, H.; Korbmacher, F.; Long, R. K. M.; Schraivogel, D.; Hawkins, J. A.; Romero-Urunuela, T.; Lopez-Gutierrez, B.; Sanz, S.; Schwab, Y.; Steinmetz, L. M.; Sharpe, J.; Bernabeu, M.
10.1101/2024.10.15.618439 — microbiology — Posted on 2025-06-03
464 Hematobiochemical Alterations and Pathological Lesions Induced by Fasciolosis in Slaughtered Cattle at Gondar ELFORA Abattoir, Ethiopia
Temesgen, A. B.; Mitiku, T.; Birhan, M.; Kebede, M. C.; Yesuf, M.; Mekonnen, M. Y.; Alemayehu, M. M.; Malede, B. A.; Geda, A. M.; Tumebo, A. W.; Shiferaw, K. A.; Wassie, Z. G.; Berie, G. K.; Mengistu, B. A.; Feleke, M. G.; Edenshaw, F.; Yitie, M. T.; Kasse, G. E.; Tsehay, E. M.; Shiferaw, S. A.
10.1101/2024.08.10.607441 — pathology — Posted on 2025-06-03
465 Kinesin-1 Autoinhibition Tunes Cargo Transport by Motor Ensembles
Bensel, B. M.; Previs, S. B.; Fagnant, P. M.; Trybus, K. M.; Walcott, S.; Warshaw, D. M.
10.1101/2025.05.06.652443 — biophysics — Posted on 2025-06-03
467 DeepPGDB: A Novel Paradigm for AI-Guided Interactive Plant Genomic Database
Li, F.; Chen, J.; Luo, W.; Liu, J.; Hou, Z.; Gan, Z.; Zhan, P.; Wang, Z.; Hu, H.; Chen, G.; Shuai, B.; Zhao, H.; Bi, C.; Wang, S.
10.1101/2025.06.01.657209 — bioinformatics — Posted on 2025-06-03
468 OPM quantum sensors enhance non-invasive neuroimaging performance
Brickwedde, M.; Anders, P.; Krueger, P.; Sander, T.; Uhlhaas, P.
10.1101/2025.05.30.657044 — neuroscience — Posted on 2025-06-03
471 The Regulation of COX-2, ABCA1 and ABCG1 by the lncRNA PACERR links the inflammatory response and cholesterol homeostasis
Hennessy, E. J.; Tanosaki, T.; Lordan, R. J.; Tang, S. Y.; Shuvaev, V.; Ghosh, S.; Das, U.; Joshi, R.; Meng, H.; Snouwaert, J. n.; Winter, H.; Maegdefessel, L.; Koller, B. N.; FitzGerald, G. A.
10.1101/2025.06.02.657432 — cell biology — Posted on 2025-06-03
472 Regulation of reticular adhesions by KANK2 and talin2 in two melanoma cell lines
Rac, A.; Loncaric, M.; Stojanovic, N.; Fatima, M.; Resetar, M.; Hrsak, D.; Humphries, J. D.; Humphries, M. J.; Ambriovic-Ristov, A.
10.1101/2025.06.02.657402 — cell biology — Posted on 2025-06-03
473 Chlamydial membrane vesicles deliver the chlamydial porin OmpA to mitochondria to inhibit apoptosis
Mesesan, A.; Oehler, H.; Kontchou, C. W.; Haimovici, A.; Helmstädter, M.; Kretz, O.; Schilling, O.; Nazarenko, I.; Matti, U.; Ries, J.; Gentle, I.; Häcker, G.
10.1101/2025.06.02.657351 — cell biology — Posted on 2025-06-03
478 Assessing plant phenological changes based on drivers of spring phenology
Jiang, Y.; Mayor, S.; Chu, X.; Ye, X.; Man, R.; Tao, J.; Dang, Q.-L.
10.1101/2025.04.13.648654 — ecology — Posted on 2025-06-03
479 A minimal hybridization capture system for the parallel enrichment and cost-effective detection of ancient human pathogens
Kocher, A.; Seguin-Orlando, A.; Clavel, P.; Louvel, G.; Jonvel, R.; Tzortzis, S.; Signoli, M.; Costedoat, C.; Orlando, L.
10.1101/2025.06.02.657376 — molecular biology — Posted on 2025-06-03
481 Single-cell spatial map of cis-regulatory elements for disease-related genes in the macaque cortex
Meng, J.; Lei, Y.; Chen, C.; Zhu, Z.; Sun, Y.; Huang, Y.; Hu, K.; Bai, Y.; Fei, T.; Liu, Z.; Li, C.; Shen, Z.; Liu, L.; Li, C.; Song, T.; Liu, C.; Poo, M.; Liu, S.; Sun, Y.
10.1101/2025.06.03.657577 — neuroscience — Posted on 2025-06-03
482 Visual processing of manipulable objects in the ventral stream is modulated by inputs from parietal action systems
Garcea, F. E.; Strawderman, E.; Burns, W.; Cotroneo, M.; Meyers, S. P.; Schmidt, T.; Walter, K. A.; Pilcher, W. H.; Mahon, B. Z.
10.1101/2025.06.01.657280 — neuroscience — Posted on 2025-06-03
483 Cysteine signaling in plant pathogen response
Moormann, J.; Heinemann, B.; Angermann, C.; Koprivova, A.; Armbruster, U.; Kopriva, S.; Hildebrandt, T. M.
10.1101/2025.03.13.642987 — plant biology — Posted on 2025-06-03
484 Action mechanism of a novel agrichemical quinofumelin against Fusarium graminearum
Xiu, Q.; Yin, X.; Chen, Y.; Zhang, Z.; Mao, Y.; Wang, T.; Zhang, J.; Zhou, M.; Duan, Y.
10.1101/2025.01.13.632717 — pathology — Posted on 2025-06-03
485 Structures of protein folding intermediates on the ribosome
Chan, S. H. S.; Streit, J. O.; Wlodarski, T.; Mitropoulou, A. N.; Cassaignau, A. M. E.; Bukvin, I. V.; Cabrita, L. D.; Christodoulou, J.
10.1101/2025.04.07.647236 — biophysics — Posted on 2025-06-03
486 EASYstrata: An All-in-One Workflow for Genome Annotation and Genomic Divergence Analysis
Rougemont, Q.; Lucotte, E.; Boyer, L.; Jalaber, A.; Snirc, A.; Giraud, T.; Rodriguez de la Vega, R. C.
10.1101/2025.01.06.631483 — genomics — Posted on 2025-06-03
487 Use of massive DNA barcoding to monitor biodiversity: a test on forest soil macrofauna
Jabot, F.; Auger, G. B.; Bonnal, P.; Pizaine, M.; Roncoroni, M.; Revaillot, S.; Pottier, J.
10.1101/2025.02.07.636998 — ecology — Posted on 2025-06-03
488 Dynamical forces drive cell and organ morphology changes during embryonic development
Manna, R. K.; Retzlaff, E. M.; Hinman, A. M.; Lan, Y.; Abdel-Razek, O.; Bates, M.; Hehnly, H.; Amack, J. D.; Manning, M. L.
10.1101/2024.07.13.603371 — developmental biology — Posted on 2025-06-03
489 Phylogenetic position and mitochondrial genome evolution of 'orphan' eukaryotic lineages
Zlatogursky, V.; Boscaro, V.; Lax, G.; Wanntorp, M.; Pohl, N.; Burki, F.; Keeling, P. J.
10.1101/2025.04.16.649146 — microbiology — Posted on 2025-06-03
491 Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
Gazzara, E.; Adrover, J. M.; Lui, A.; Han, S.; Aminzada, Z.; Bhandari, N.; Sivetz, N.; Shirue, V. S.; Shergill, B. S.; Curtis, M. B.; George, S. C.; Cicala, A.; Rishi, A.; Chung, C.; Devoe, C.; Huang, H.; Weiss, M.; Lou, E.; Tuveson, D. A.; Beyaz, S.; Westcott, P. M. K.; Egeblad, M.; Gholami, S.
10.1101/2025.05.30.657122 — cancer biology — Posted on 2025-06-03
492 A missense mutation in Muc2 promotes gut microbiome- and metabolome-dependent colitis-associated tumorigenesis.
Verna, G.; De Santis, S.; Islam, B.; Sommella, E. M.; Licastro, D.; Zhang, L.; De Almeida Celio, F.; Merciai, F.; Caponigro, V.; Campiglia, P.; Pizarro, T. T.; Chieppa, M.; Cominelli, F.
10.1101/2025.05.31.657160 — cancer biology — Posted on 2025-06-03
493 Klf4-dependent pivotal role of smooth muscle-derived Gli1+ lineage progenitor cells in lung cancer progression
Lu, S.; Navarro, A. C.; Johnson, A. M.; Noble, T.; Jolly, A. J.; Moulton, K. S.; Nemenoff, R. A.; Weiser-Evans, M. C.
10.1101/2025.05.30.657094 — cancer biology — Posted on 2025-06-03
494 KOLF2.1J iTF-Microglia: A standardized platform to studymicroglial transcriptional regulatory networks in CNS disease
Rodriguez-Nunez, I.; Bartley, S. C.; Taylor, J. W.; Johnston, S. Q.; Rogers, B. B.; Meadows, S. K.; Newberry, K. M.; Cochran, J. N.; Myers, R. M.
10.1101/2025.05.30.657077 — genomics — Posted on 2025-06-03
497 WNK1 kinase activity is required for maintenance of podocyte structure
Liu, Z.; Lee, E.; Jiang, S.; Yoon, J.; Ahmed, F.; Rahman, M. A.; Bleicher, W. P.; Suleiman, H. Y.; Bruggeman, L. A.; Miller, R. T.; Chang, A. N.
10.1101/2025.05.30.657136 — cell biology — Posted on 2025-06-03
498 Spatial Heterogeneity of Macrophages in the Human Lung
Hume, P. S.; Lyn-Kew, K. H.; Wynn, E. A.; Steinhart, B.; Driscoll, J.; Jacobson, S.; Henson, P. M.; Mould, K. J.; Moore, C. M.; Janssen, W. J.
10.1101/2025.05.30.657106 — immunology — Posted on 2025-06-03
500 VGLL3-centered network connects placental, vascular, and immune defects in preeclampsia
Plazyo, O.; Chopp, L. B.; Peela, R.; Young, K.; Zhang, H.; Bogle, R.; Hesson, A.; Langen, E.; Bergin, I. L.; Syu, L.-J.; Erba, J.; Kirma, J.; Dey, P.; Zhang, L.; Sarkar, M. K.; Swindell, W. R.; Gallagher, K. A.; Ward, N. L.; Singer, K.; Kahlenberg, J. M.; Billi, A. C.; Dlugosz, A. A.; Ganesh, S. K.; Tsoi, L. C.; Gudjonsson, J. E.
10.1101/2025.05.30.657097 — immunology — Posted on 2025-06-03
503 DNA-based delivery of incretin receptor agonists using MYO Technology leads to durable weight loss in a diet-induced obesity model
Sasset, L.; Cameron, A. D.; Sussman, C.; Rubinelli, L.; Maji, D.; Miller, R.; Thompson, A. T.; Campbell, D.; Walker, M. R.; Drozdz, M. M.; Liberatore, R. A.
10.1101/2025.05.30.656889 — physiology — Posted on 2025-06-03
505 A network medicine framework for multi-modal data integration in therapeutic target discovery
Baltusyte, G.; Toleman, I.; Jones, J.; Welsh, S. J.; Stewart, G. D.; Mitchell, T. J.; Saeb-Parsy, K.; Han, N.
10.1101/2025.05.29.656813 — bioinformatics — Posted on 2025-06-03
510 Turbulence orchestrates actin-mitochondria dynamics to preserve GPIbα and support iPSC-derived platelet biogenesis
Nakamura, E.; Harada, Y.; Nakamura, S.; Fujio, K.; De Wispelaere, K.; Thys, C.; Freson, K.; Yamamoto, T.; Sawaguchi, A.; Suetsugu, S.; Eto, K.
10.1101/2025.05.22.655481 — cell biology — Posted on 2025-06-03
511 Circular RNAs accumulate in ageing human placental tissue and in stillbirth, leading to DNA damage and cellular senescence
Arthurs, A. L.; Jackson, M. R.; McCullough, D.; SCOTT, H.; Barnett, C. P.; Webb, S. T.; Smith, M. D.; Jankovic-Karasoulos, T.; Dekker, G. A.; Roberts, C. T.
10.1101/2024.09.02.610398 — molecular biology — Posted on 2025-06-03
513 Recurrent Emergence of Boundary Cell Types During Evolution of Floral Bullseye Patterns
Oud, S.; Zurowski, M. M.; van der Jagt, P. L.; Yeo, M. T. S.; Walker, J. F.; Moyroud, E.; Vroomans, R. M. A.
10.1101/2025.05.03.651954 — systems biology — Posted on 2025-06-03
514 The signature of reproduction on wood anatomy in European beech reveals potential for masting reconstruction
Resente, G.; Crivellaro, A.; Fleurot, E.; Piermattei, A.; Maimone, F.; Wilmking, M.; Hacket-Pain, A.; Motta, R.; Ascoli, D.
10.1101/2025.05.27.656364 — plant biology — Posted on 2025-06-03
516 Enabling Plasmid-based Expression in Clostridium kluyveri using a Biparental Methylation-Conjugation System
Agena, E. M.; Badani, A. A.; Lindner, B. G.; Gois, I. M.; Dempster, A. W.; Minton, N. P.; Mahadevan, R.; Lawson, C. E.
10.1101/2025.05.30.657078 — bioengineering — Posted on 2025-06-03
519 Increased Genetic Protection Against Alzheimer's Disease in Centenarians
Bae, H.; Song, Z.; Ali, A.; Sasaki, T.; Tesi, N.; Lords, H.; Leshchyk, A.; Abe, Y.; Hirose, N.; Arai, Y.; Barzilai, N.; Weiss, E. F.; Hulsman, M.; van der Lee, S. J.; van Schoor, N. M.; Huisman, M.; Pijnenburg, Y. A. L.; van der Flier, W. M.; Reinders, M.; Holstege, H.; Milman, S.; Perls, T.; Andersen, S. L.; Sebastiani, P.
10.1101/2025.06.02.657442 — genetics — Posted on 2025-06-03
520 Composition variations in archaeological human bone proteomes
Asmundsdottir, R. D.; Troche, G.; Olsen, J. V.; Schrader, S.; Welker, F.
10.1101/2025.06.02.657369 — evolutionary biology — Posted on 2025-06-03
521 Purinergic receptor activation rectifies autism-associated endothelial dysfunction
Ouellette, J.; Warsi, S.; Romero, P.; Khare, P.; Naz, S.; Aubert-Tandon, L.; Pileggi, C.; Yandiev, S.; Freitas-Andrade, M.; Comin, C. H.; Harper, M.-E.; Manickam, D. S.; Dabertrand, F.; Saghatelyan, A.; Lacoste, B.
10.1101/2025.06.02.657522 — cell biology — Posted on 2025-06-03
528 Aberrant cerebrovascular reactivity presents as an early biomarker of psychosis susceptibility in patients with 22q11.2DS
Delavari, F.; Moia, S.; Forrer, S.; Sandini, C.; Kojovic, N.; Pascucci, A.; Lacour, C.; Eliez, S.; Van De Ville, D.
10.1101/2025.06.02.657392 — neuroscience — Posted on 2025-06-03
529 Autism-associated SCN2A deficiency disrupts cortico-striatal circuitry in human brain assembloids
Chen, X.; Zhang, J.; Wu, J.; Robinson, M. J.; Kothandaraman, H.; Yoo, Y.-E.; Dopeso-Reyes, I. M. G.; Buffenoir, T. D.; Halurkar, M. S.; Zhang, Z.; Wang, M.; Creager, E. N.; Zhao, Y.; Olivero-Acosta, M. I.; Wettschurack, K. W.; Que, Z.; Yuan, C.; Schaser, A. J.; Lanman, N. A.; Rochet, J.-C.; Skarnes, W. C.; Kremer, E. J.; Yang, Y.
10.1101/2025.06.02.657036 — neuroscience — Posted on 2025-06-03
532 Multimodal Validation of the Existence of Transitional Cerebellar Progenitors in the Human Fetal Cerebellum
Luo, Z.; Xia, M.; Zhang, F.; Xin, D.; Rao, R.; Kiang, K.; Berry, K.; Xiong, Y.; Liu, H.; Lin, Y.; Hu, M.; Xin, M.; Ma, J.; Li, H.; Taylor, M. D.; Zhou, W.; Lu, Q. R.
10.1101/2025.06.01.657310 — developmental biology — Posted on 2025-06-03
533 An applicable and efficient retrograde monosynaptic circuit mapping tool for larval zebrafish
Chen, T.; Deng, Q.; Lin, K.; Zheng, X.; Wang, X.; Zhong, Y.; Ning, X.; Li, Y.; Xu, F.; Du, J.; Du, X.
10.1101/2024.06.27.601104 — neuroscience — Posted on 2025-06-02
535 Evaluation of a prototype Orbitrap Astral Zoom mass spectrometer for quantitative proteomics - Beyond identification lists
Hsu, C.; Shulman, N.; Stewart, H.; Petzoldt, J.; Pashkova, A.; Plubell, D.; Denisov, E.; Hagedorn, B.; Damoc, E.; MacLean, B. X.; Remes, P. M.; Canterbury, J. D.; Makarov, A.; Hock, C.; Zabrouskov, V.; Wu, C. C.; MacCoss, M. J.
10.1101/2025.05.30.657132 — biochemistry — Posted on 2025-06-02
538 Alpha and Beta Oscillations Mediate the Effect of Motivation on Neural Coding of Cognitive Flexibility
Delgado, J. M. C.; Ison, M. J.; Muhle-Karbe, P. S.; Stokes, M. G.; Hall-McMaster, S.; Myers, N. E.
10.1101/2025.03.11.642697 — neuroscience — Posted on 2025-06-02
539 In vivo deep-brain microscopy at submicrometer resolution with refractive index-matched prism interfaces
Takahashi, T.; Zhou, Y.; Tsutsumi, M.; Ito, C.; Hatakeyama, A.; Ishii, H.; Saitoh, A.; Yukawa, H.; Nabekura, J.; Nemoto, T.; Otomo, K.; Matsuhisa, N.; Agetsuma, M.
10.1101/2025.05.30.657010 — neuroscience — Posted on 2025-06-02
540 Quantum Cognition Machine Learning for Forecasting Chromosomal Instability
Di Caro, G.; Kirakosyan, V.; Abanov, A. G.; Candelori, L.; Hartmann, N.; Lam, E. T.; Musaelian, K.; Samson, R.; Villani, D.; Wells, M. T.; Wenstrup, R. J.; Xu, M.
10.1101/2025.05.30.656882 — cancer biology — Posted on 2025-06-02
541 Biomni: A General-Purpose Biomedical AI Agent
Huang, K.; Zhang, S.; Wang, H.; Qu, Y.; Lu, Y.; Roohani, Y.; Li, R.; Qiu, L.; Zhang, J.; Di, Y.; Marwaha, S.; Carter, J.; Zhou, X.; Wheeler, M. T.; Bernstein, J.; Wang, M.; He, P.; Zhou, J.; Snyder, M.; Cong, L.; Regev, A.; Leskovec, J.
10.1101/2025.05.30.656746 — bioinformatics — Posted on 2025-06-02
547 Venus-MAXWELL: Efficient Learning of Protein-Mutation Stability Landscapes using Protein Language Models
Yu, Y.; Jiang, F.; Ma, X.; Zhang, L.; Zhong, B.; Ouyang, W.; Fan, G.; Yu, H.; Hong, L.; Li, M.
10.1101/2025.05.30.656964 — bioinformatics — Posted on 2025-06-02
550 Sex specific correction of maternal inflammation-induced behavioral abnormalities by the inhibition of colony-stimulating factor 1 receptor
Delpech, J. C.; Yeh, H.; Kalavai, S. V.; You, Y.; Ruan, Z.; Touch, N.; Hersh, S.; Monguillon, P.; Johnson, W. E.; Rau, A.; Madore-Delpech, C.; Ikezu, T.; Ikezu, S.
10.1101/2025.05.30.657085 — animal behavior and cognition — Posted on 2025-06-02
554 Must epidemiologically impactful vector control interventions disrupt mosquito population structure? A case study of a cluster-randomised controlled trial.
Dennis, T. P. W.; Guelbeogo, W. M.; Ferguson, H. M.; Lindsay, S.; N'Fale, S.; Pignatell, P.; Ranson, H.; Sanou, A.; Tiono, A.; Weetman, D.; Viana, M.
10.1101/2025.04.16.649034 — ecology — Posted on 2025-06-02
555 piRNAs are abundant in the early embryo of the crustacean Parhyale hawaiensis
Calvo Gonzalez, L.; Pettini, T.; Ylla, G.; Ronshaugen, M. R.; Griffiths-Jones, S.
10.1101/2025.05.30.656998 — developmental biology — Posted on 2025-06-02
556 Engineering a mouse-adapted SADS-CoV and establishing a neonatal mouse model to study its infection
Zhang, H.; Zhou, J.; Li, P.; Zhang, M.; Jing, R.; Zhu, H.; Lang, Y.; He, Q.; Zhang, M.; Li, W.
10.1101/2025.06.02.657353 — microbiology — Posted on 2025-06-02
557 Genome-wide CRISPR/Cas9 knockout screen identifies host factors essential for Bovine Parainfluenza Virus Type 3 replication
Hao, J.; Gao, X.; Light, C.; Sun, Y.; Lu, S.; Tian, Y.; Gao, X.; Su, Y.; Gao, J.; Huang, X.; Wang, J.; Zhang, Q.; Hai, R.; Hu, W.; Wang, G.
10.1101/2025.06.02.657355 — microbiology — Posted on 2025-06-02
558 HLA-DQ monomer-based enrichment of alloreactive CD4 T cells
Zhanzak, Z.; Cina, D.; Zhang, X.; Hadley, A.; Kissick, H.; Larsen, C.
10.1101/2025.05.30.656890 — immunology — Posted on 2025-06-02
559 Multi-Stable Bimodal Perceptual Coding within the Ventral Premotor Cortex
Andrade-Ortega, B.; Diaz, H.; Bayones, L.; Alvarez, M.; Zainos, A.; Rivera-Yoshida, N.; Franci, A.; Romo, R.; Rossi-Pool, R.
10.1101/2024.12.11.628069 — neuroscience — Posted on 2025-06-02
561 Single-cell transcriptomics uncovers that cell-to-cell communication controls p53 activation
Castellano, L.; Robinson, M. E.; Dabrowska, A.; Feldhahn, N.; Ottaviani, S.; Stebbing, J.
10.1101/2025.05.30.657016 — cancer biology — Posted on 2025-06-02
564 The effect of aging on post-translational modifications of wild-type human SOD1 and the A5V ALS mutant
de Souza, G. F.; Magalhaes, R. S. S.; Neto, J. R. M.; Martins, M.; Follmer, C.; Junqueira, M.; Eleutherio, E. C. A.
10.1101/2025.06.02.657411 — biochemistry — Posted on 2025-06-02
565 Spatial metabolic gradients in the liver and small intestine
Samarah, L. Z.; Zheng, C.; Xing, X.; Lee, W. D.; Afriat, A.; Chitra, U.; MacArthur, M.; Lu, W.; Jankowski, C. S. R.; Ma, C.; Hunter, C. J.; Raphael, B. J.; Rabinowitz, J. D.
10.1101/2025.06.02.657306 — biochemistry — Posted on 2025-06-02
567 Time Series GWAS for Iron Deficiency Chlorosis Tolerance in Soybean using Aerial Imagery
Carroll, M. E.; Rairdin, A. M.; Van der Laan, L.; Ferela, A.; Hanumolu, S.; Sarkar, S.; Ganapathysubramanian, B.; Singh, A.; Singh, A. K.
10.1101/2025.05.30.657051 — genetics — Posted on 2025-06-02
570 Protists Exhibit Stronger and More Recent Oceanic Genetic Structure than Archaeplastida and Metazoa
Gonzalez-Miguens, R.; Galvez-Morante, A.; Torruella, G.; Berney, C.; Casacuberta, E.; Ruiz-Trillo, I.
10.1101/2025.06.02.657477 — microbiology — Posted on 2025-06-02
571 Human Cytomegalovirus UL78 is a Nuclear-Localized GPCR Necessary for Efficient Reactivation from Latent Infection in CD34+ Hematopoietic Progenitor Cells
Medica, S.; Diggins, N. L.; Denton, M.; Turner, R. L.; Pung, L. J.; Mayo, A. T.; Mitchell, J.; Slind, L.; Nguyen, L. K.; Beechwood, T. A.; Sulgey, G.; Kreklywich, C. N.; Malouli, D.; Caposio, P.; Streblow, D. N.; Hancock, M. H.
10.1101/2025.06.02.657350 — microbiology — Posted on 2025-06-02
572 Phylogeny-aware comparative genomics of Vibrio vulnificus links genetic traits to pathogenicity
Delgado, L. F.; Riedinger, D. J.; Fernandez-Juarez, V.; Herlemann, D. P. R.; Pansch, C.; Katarzyte, M.; Gyraite, G.; Reusch, T. B. H.; Rakowski, M.; Piwosz, K.; Wozniczka, A.; Benterbusch-Brockmöller, H.; Sperlea, T.; Dupke, S.; Scholz, H. C.; Kube, S.; Riemann, L.; Labrenz, M.; Andersson, A.
10.1101/2025.06.02.657354 — microbiology — Posted on 2025-06-02
574 Episymbiotic Saccharibacteria suppresses epithelial immunoactivation through Type IV pili and TLR2 dependent endocytosis
Chouhan, D.; Grossman, A. S.; Kerns, K. A.; Stocke, K. S.; Kim, M.; Dong, P.-T.; Kumar, A.; Lei, L.; Lamont, R. J.; McLean, J. S.; He, X.; Bor, B.
10.1101/2025.05.30.656655 — immunology — Posted on 2025-06-02
576 From Belief to Brain: How Growth Mindset Optimizes Cortico-Striatal Dynamics for Cognitive Development
Zhao, Y.; Cui, J.; Zhang, Z.; Zhao, H.; Xu, J.; Chen, M.; Hao, L.; He, Y.; Wang, H.; Wang, Y.; Wang, D.; Hu, Y.; Han, Z. R.; Tan, S.; Men, W.; Gao, J.; Chen, L.; He, Y.; Tao, S.; Dong, Q.; Qin, S.
10.1101/2022.07.11.499525 — neuroscience — Posted on 2025-06-02
579 LRRK2 regulates synaptic function through modulation of actin cytoskeletal dynamics
Tombesi, G.; Kompella, S.; Favetta, G.; Chen, C.; Ornaghi, M.; Zhao, Y.; Morosin, E.; Sevegnani, M.; Lama, A.; Marte, A.; Battisti, I.; Iannotta, L.; Plotegher, N.; Civiero, L.; Onofri, F.; Eickholt, B. J.; Piccoli, G.; Arrigoni, G.; Beccano-Kelly, D.; Manzoni, C.; Parisiadou, L.; Greggio, E.
10.1101/2022.10.31.514622 — neuroscience — Posted on 2025-06-02
585 Quantitative isoform profiling using deep coverage long-read RNA sequencing across early endothelial differentiation
Wissel, D.; Mehlferber, M. M.; Nguyen, K. M.; Pavelko, V.; Tseng, E.; Robinson, M. D.; Sheynkman, G. M.
10.1101/2025.05.30.656561 — bioinformatics — Posted on 2025-06-02
586 Biocompatible Multi-functional Polymeric Material for Mineralized Tissue Adhesion
Luo, Y.; Zhang, C.; Fulco, S.; Liu, J.; Chen, K.; Hu, Y.; Jiang, Y.; Xu, R.; Rakesh, L.; Ozer, F.; Tertuliano, O.; Turner, K.; Vining, K. H.
10.1101/2025.05.30.656989 — bioengineering — Posted on 2025-06-02
587 Enabling Plasmid-based Expression in Clostridium kluyveri using a Biparental Methylation-Conjugation System
Agena, E. M.; Badani, A. A.; Linder, B. G.; Gois, I. M.; Dempster, A. W.; Minton, N. P.; Mahadevan, R.; Lawson, C. E.
10.1101/2025.05.30.657078 — bioengineering — Posted on 2025-06-02
592 Differential metaproteomics of bacteria grown in vitro and in planta reveals functions used during growth on maize roots
Garrell, A.-K.; Cheadle, J.; Crook, N.; Pal, G.; Septer, A. N.; Wagner, M. R.; Beck, A. E.; Kleiner, M.
10.1101/2025.06.02.657423 — microbiology — Posted on 2025-06-02
596 GENOTYPIC DETECTION OF ANTIBIOTIC-RESISTANT GENES IN EMERGING BACTERIAL PATHOGENS FROM NEONATAL SEPSIS PATIENTS IN LAGOS
Adegboyega, H. O.; Banjo, T. A.; Deji-Agboola, A. M.; Iwalokun, B.; Mutiu, W. B.; Osinupebi, O. A.; Shorunmu, T. O.; Oladoja, F. A.; Fatungase, O. M.; Adeyanju, M. M.; Akindele, R. A.; Fakunle, P. B.; Olabode, B. A.; Ajayi, O. O.; Onadeko, O.; Oyelekan, A. A. A.; Oritogun, K. S.; Ariyibi, S. O.; Omirin, E. S.
10.1101/2025.06.02.657359 — microbiology — Posted on 2025-06-02
600 Differential Decay of Multiple eNA Components from a Cetacean
Brandao-Dias, P. F.; Shaffer, M.; Guri, G.; Parsons, K. M.; Kelly, R. P.; Allan, E. A.
10.1101/2025.05.09.653189 — molecular biology — Posted on 2025-06-02
601 Antibiotic potentiation and inhibition of cross-resistance in pathogens associated with cystic fibrosis
Kaderabkova, N.; Furniss, R. C. D.; Maslova, E.; Potter, K. E.; Eisaiankhongi, L.; Bernal, P.; Filloux, A.; Landeta, C.; Gonzalez, D.; McCarthy, R. R.; Mavridou, D.
10.1101/2023.08.02.551661 — microbiology — Posted on 2025-06-02
602 Mapping early patterning events in human neural development usingan in-vitro microfluidic stem cell model
Rathore, G. S.; Ankjaer, M.; Rifes, P.; Hanninen, E.; Calleja, F. S.; Rusimbi, C.; Kajtez, J.; Nygaard, A. H.; Piilgaard, L. S.; Dubonyte, U.; Norgaard, Z. A.; Christensen, J. B.; Egerod, K. L.; Camp, J. G.; Pers, T.; Treutlein, B.; Kirkeby, A.
10.1101/2025.05.23.655442 — neuroscience — Posted on 2025-06-02
603 Human gut commensal Alistipes timonensis modulates the host lipidome and delivers anti-inflammatory outer membrane vesicles to suppress colitis in an Il10-deficient mouse model
Older, E. A.; Mitchell, M. K.; Campbell, A.; Lian, X.; Madden, M.; Wang, Y.; van de Wal, L. E.; Zaw, T.; VanderVeen, B. N.; Tatum, R.; Murphy, E. A.; Chen, Y.-H.; Fan, D.; Ellermann, M.; Li, J.
10.1101/2024.10.23.619966 — biochemistry — Posted on 2025-06-02
607 AcrIF11 is a potent CRISPR-specific ADP-ribosyltransferase encoded by phage and plasmid
Chen, D. F.; Roe, L. T.; Li, Y.; Borges, A. L.; Zhang, J. Y.; Babbar, P.; Maji, S.; Stevens, M. G. V.; Correy, G. J.; Diolaiti, M. E.; Smith, D. H.; Ashworth, A.; Stroud, R. M.; Kelly, M. J. S.; Bondy-Denomy, J.; Fraser, J. S.
10.1101/2024.08.26.609590 — microbiology — Posted on 2025-06-02
608 Intrinsic dynamic shapes responses to external stimulation in the human brain
Nentwich, M.; Leszczynski, M.; Schroeder, C. E.; Bickel, S.; Parra, L. C.
10.1101/2024.08.05.606665 — neuroscience — Posted on 2025-06-02
610 Automated Classification of Sleep-Wake States and Seizures in Mice
Harvey, B. J.; Olah, V. J.; Aiani, L. M.; Rosenberg, L. I.; Lasky, D. J.; Moxon, B.; Pedersen, N. P.
10.1101/2023.04.07.536063 — neuroscience — Posted on 2025-06-02
612 Microtubule forces drive nuclear damage in LMNA cardiomyopathy
Amiad Pavlov, D.; Heffler, J.; Corredera, C. S.; Dehghany, M.; Shen, K. M.; Zuela-Sopilniak, N.; Randell, R.; Uchida, K.; Jain, R.; Shenoy, V.; Lammerding, J.; Prosser, B. L.
10.1101/2024.02.10.579774 — cell biology — Posted on 2025-06-02
614 Whole-brain meso-vein imaging in living humans using fast 7 T MRI
Gulban, O. F.; Stirnberg, R.; Tse, D. H. Y.; Pizzuti, A.; Koiso, K.; Archila-Melendez, M. E.; Huber, R.; Bollmann, S.; Goebel, R.; Kay, K.; Ivanov, D.
10.1101/2025.03.23.644588 — neuroscience — Posted on 2025-06-02
615 Evolution of object identity information in sensorimotor cortex throughout grasp
Yan, Y.; Sobinov, A. R.; Goodman, J. M.; Okorokova, E. V.; Miller, L. E.; Bensmaia, S. J.
10.1101/2024.10.11.617909 — neuroscience — Posted on 2025-06-02
617 Persistent dopamine-dependent remodeling of the neural transcriptome in response to pregnancy and postpartum
Chan, J. C.; Di Salvo, G.; Cunningham, A. M.; Dutta, S.; Brindley, E. A.; Weekley, B. H.; Wan, E.; Zhang, C.; Mechawar, N.; Turecki, G.; Maze, I.
10.1101/2025.02.20.639313 — neuroscience — Posted on 2025-06-02
619 FEDRANN: effective overlap graph construction based on dimensionality reduction and approximate nearest neighbors
Zhang, J.-Y.; Miao, C.; Qiu, T.; Xia, X.; He, L.; He, J.; Sun, Y.; Zeng, T.; Li, Y.; Xu, X.; Ruan, Y.; Dong, Y.
10.1101/2025.05.30.656979 — bioinformatics — Posted on 2025-06-02
621 MARLOWE: Taxonomic Characterization of Unknown Samples for Forensics Using De Novo Peptide Identification
Jenson, S. C.; Chu, F.; Alves, G.; Ogurtsov, A. Y.; Barente, A. S.; Crockett, D. L.; Lamar, N. C.; Merkley, E. D.; Yu, Y.-K.; Jarman, K. H.
10.1101/2024.09.30.615220 — bioinformatics — Posted on 2025-06-02
625 Persistent Decision-Making in Mice, Monkeys, and Humans
Laurie, V.-J.; Shourkeshti, A.; Chen, C. S.; Herman, A. B.; Grissom, N. M.; Ebitz, R. B.
10.1101/2024.05.07.592970 — animal behavior and cognition — Posted on 2025-06-02
627 A haplotype-resolved view of human gene regulation
Vollger, M. R.; Swanson, E. G.; Neph, S. J.; Ranchalis, J.; Munson, K. M.; Ho, C.-H.; Cheng, Y. H. H.; Sedeno-Cortes, A. E.; Fondrie, W. E.; Bohaczuk, S. C.; Dippel, M. A.; Mao, Y.; Parmalee, N. L.; Mallory, B. J.; Harvey, W. T.; Kwon, Y.; Garcia, G. H.; Hoekzema, K.; Meyer, J. G.; Cicek, M.; Eichler, E. E.; Noble, W. S.; Witten, D. M.; Bennett, J. T.; Ray, J. P.; Stergachis, A. B.
10.1101/2024.06.14.599122 — genomics — Posted on 2025-06-02
628 Human cytomegalovirus infection coopts chromatin organization to diminish TEAD1 transcription factor activity
Sayeed, K.; Parameswaran, S.; Beucler, M. J.; Edsall, L. E.; VonHandorf, A.; Crowther, A.; Donmez, O. A.; Hass, M. R.; Richards, S.; Forney, C. R.; Hesse, H. K.; Jones, S. H.; Dunn, K. A.; Wright, J.; Leong, M. M.; Murray-Nerger, L. A.; Yechoor, V. K.; Gewurz, B. E.; Kaufman, K. M.; Harley, J. B.; Zhao, B.; Miller, W. E.; Kottyan, L. C.; Weirauch, M. T.
10.1101/2024.04.12.588762 — genomics — Posted on 2025-06-02
629 A curated dataset and web application for Integrative Analysis of Ancient DNA from Britain and Ireland
Metz, S.; Fischer, C.-E.; Bleasdale, M.; Castells Navarro, L.; Buster, L.; Legge, M.; Reich, D.; Armit, I.
10.1101/2025.05.30.657009 — genetics — Posted on 2025-06-02
637 Synthetic Serum Markers Enable Noninvasive Monitoring of Gene Expression in Primate Brains
Lee, S.; Romac, M.; Watanabe, S.; Chernov, M.; Li, H.; Raisley, E.; Szablowski, J. O.; Costa, V. D.
10.1101/2025.06.01.657212 — neuroscience — Posted on 2025-06-02
639 C9orf72 polyGA knock-in mice exhibit mild motor and proteomic changes consistent with ALS/FTD
Milioto, C.; Carcole, M.; Zanovello, M.; Ahmed, M.; Nirujogi, R. S.; Biggs, D.; Katona, E.; Glaria, I.; Santos, A.; Devoy, A.; Fratta, P.; Alessi, D. R.; Davies, B.; Greensmith, L.; Fisher, E.; Isaacs, A. M.
10.1101/2025.05.30.656994 — neuroscience — Posted on 2025-06-02
642 Phenotypic and transcriptomic characterization of bicalutamide and enzalutamide resistance in castration-resistant prostate cancer cells
Natkin, R.; Paloneva, M. I.; Raittinen, P. V.; Syvala, H.; Blauer, M.; Tammela, T. L.; Ilmonen, P.; Nykter, M.; Siltari, A.; Murtola, T. J.
10.1101/2025.05.30.656961 — cancer biology — Posted on 2025-06-02
647 Visual working memory precision is under voluntary control
Sahakian, A.; Koevoet, D.; Paffen, C. L. E.; Gayet, S.; Van der Stigchel, S.
10.1101/2025.05.29.656854 — neuroscience — Posted on 2025-06-02
648 Spine-Prints: Transposing Brain Fingerprints to the Spinal Cord
Ricchi, I.; Santoro, A.; Kinany, N.; Landelle, C.; Khatibi, A.; Vahdat, S.; Doyon, J.; Barry, R. L.; Van De Ville, D.
10.1101/2025.05.30.656545 — neuroscience — Posted on 2025-06-02
651 Gestational Chronic Intermittent Hypoxia Triggers Maternal Inflammation and Disrupts Placental Stress Responses
Gardner, J. J.; Oliveira da Silva, R. d. N.; Bradshaw, J. L.; Mabry, S.; Wilson, E. N.; Hula, N.; Tucker, S. M.; Gorham, I. K.; Escalera, D.; Lopez, L.; Phillips, N. R.; Cunningham, R. L.; Goulopoulou, S.
10.1101/2025.05.29.656944 — physiology — Posted on 2025-06-02
652 CASP16 protein monomer structure prediction assessment
Yuan, R.; Zhang, J.; Kryshtafovych, A.; Schaeffer, R. D.; Zhou, J.; Cong, Q.; Grishin, N. V.
10.1101/2025.05.29.656942 — biophysics — Posted on 2025-06-02
661 A cell atlas of the developing human outflow tract of the heart and its adult derivatives
Leshem, R.; Murtuza Baker, S.; Mallen, J.; Wang, L.; Dark, J.; Rattray, M.; Sharrocks, A.; Piper Hanley, K.; Hanley, N.; Bamforth, S.; Bobola, N.
10.1101/2023.04.05.535627 — developmental biology — Posted on 2025-06-02
662 Conserved and Unique Features of Terminal Telomeric Sequences in ALT-Positive Cancer Cells
Azeroglu, B.; Wu, W.; Pavani, R.; Sandhu, R.; Matsumoto, T.; Nussenzweig, A.; Lazzerini Denchi, E.
10.1101/2025.02.27.640565 — molecular biology — Posted on 2025-06-02
664 Synthetic Serum Markers Enable Noninvasive Monitoring of Gene Expression in Primate Brains
Lee, S.; Romac, M.; Romac, M. D.; Chernov, M.; Li, H.; Raisley, E.; Szablowski, J. O.; Costa, V. D.
10.1101/2025.06.01.657212 — neuroscience — Posted on 2025-06-02
667 Informed Data-Independent Acquisition Enables Targeted Quantification of Key Regulatory Proteins in Cell Fate Decision at Single-Cell Resolution
Woessmann, J.; Petrosius, V.; Schovsbo, S.; Arrey, T. N.; Furtwaengler, B.; Op de Beeck, J.; Damoc, E.; Porse, B. T.; Schoof, E. M.
10.1101/2025.05.30.656945 — systems biology — Posted on 2025-06-02
668 Active learnings impact on student course performance in STEM varies by type and intensity
Xu, S.; Velasco, V.; Hill, M. J.; Tran, E.; Agrawal, S.; Arroyo, E. N.; Behling, S.; Chambwe, N.; Cintron, D. L.; Cooper, J. D.; Dunster, G.; Grummer, J. A.; Hennessey, K.; Hsiao, J.; Iranon, N.; Jones, L.; Jordt, H.; Keller, M.; Lacey, M. E.; Littlefield, C. E.; Lowe, A.; Newman, S.; Okolo, V.; Olroyd, S.; Peecook, B. R.; Pickett, S. B.; Slager, D. L.; Caviedes-Solis, I. W.; Stanchak, K. E.; Sundaravaradan, V.; Valdebenito, C.; Williams, C. R.; Zinsli, K. A.; Freeman, S.; Theobald, E. J.
10.1101/2025.06.01.657285 — scientific communication and education — Posted on 2025-06-02
669 Prediction of harvest-related traits in barley using high-throughput phenotyping data and machine learning
Tietze, H.; Abdelhakim, L.; Pleskacova, B.; Kurtz-Sohn, A.; Fridman, E.; Nikoloski, Z.; Panzarova, K.
10.1101/2025.05.29.656856 — plant biology — Posted on 2025-06-02
671 Perinatal Asphyxia Alters Physiological Responses and Ex Vivo Cardiovascular Function of Preterm Growth-Restricted Lambs
Azman, Z.; Piscopo, B. R.; Sutherland, A. E.; Thiel, A.; Zahra, V.; Pham, Y.; Nitsos, I.; Hossain, M. M.; Malhotra, A.; Miller, S. L.; Bubb, K. J.; Polglase, G. R.; Allison, B. J.
10.1101/2025.05.27.656490 — physiology — Posted on 2025-06-02
672 Regulation of Aldosterone Secretion by Substance P and the NK1 Receptor in Aldosterone-Producing Adenomas
Lopez, A.-G.; Duparc, C.; Renouf, S.; D'Agostino, M.; De Sousa, K.; Amar, L.; Defortescu, G.; Manceau, G.; Sabourin, J.-C.; Fernandes-Rosa, F. L.; Zennaro, M.-C.; Meatchi, T.; Nicolas, G.; Louiset, E.; Lefebvre, H.
10.1101/2025.05.28.656733 — physiology — Posted on 2025-06-02
679 Structure of a novel contractile injection system in Salmonella enterica subsp. salamae
Ejaz, R. N.; Funke, K.; Kielkopf, C. S.; Martin, F. J. O.; Siborova, M.; Hendriks, I. A.; Sofos, N. H.; Pape, T. H.; Steiner-Rebrova, E. M.; Nielsen, M. L.; Erhardt, M.; Taylor, N. M. I.
10.1101/2025.06.01.657177 — microbiology — Posted on 2025-06-02
682 From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons
Tasciotti, S.; Iascone, D. M.; Chavlis, S.; Hammond, L.; Katz, Y.; Losonczy, A.; Polleaux, F.; Poirazi, P.
10.1101/2025.05.30.657022 — neuroscience — Posted on 2025-06-02
683 Large Language Models Reveal the Neural Tracking of Linguistic Context in Attended and Unattended Multi-Talker Speech
Puffay, C.; Mischler, G.; Choudhari, V.; Vanthornhout, J.; Bickel, S.; Mehta, A. D.; Schevon, C. A.; McKhann, G. M.; Van hamme, H.; Francart, T.; Mesgarani, N.
10.1101/2025.04.24.648897 — neuroscience — Posted on 2025-06-02
685 NEUROGLIAL CB1 RECEPTORS CONTROL NAVIGATION STRATEGIES
Egana-Huguet, J.; Sangroniz-Beltran, L.; Baraibar, A. M.; Reyes-Velasquez, P.; Landgraf, N.; Torres-Maldonado, P.; Rodriguez-Cedres, C.; Julio-Kalajzic, F.; Piriz, J.; Ramos-Uriarte, A.; Grandes, P.; Marsicano, G.; Mato, S.; Ceprian, M.; Soria-Gomez, E.
10.1101/2025.05.27.656352 — neuroscience — Posted on 2025-06-02
686 Separate timescales for spatial and anatomical information processing of body stimuli
Waltzing, B. M.; McAteer, S.; Moreno-Verdu, M.; Van Caenegem, E. E.; Du, Y.; Hardwick, R. M.
10.1101/2024.10.07.616993 — neuroscience — Posted on 2025-06-02
687 An in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
Pinon, L.; Chabaud, M.; Nivoit, P.; Wong-Ng, J.; Nguyen, T.-T.; Paul, V.; Bouquerel, C.; Goussard, S.; Smilovici, P.; Frachon, E.; Obino, D.; Gobaa, S.; Dumenil, G.
10.1101/2024.02.09.579276 — synthetic biology — Posted on 2025-06-02
689 IRE1 activity regulates tumour and microenvironment cell lineage states while stratifying localised and metastatic prostate cancer.
Doultsinos, D.; Tomljanovic, I.; Pilalis, E.; Abusamra, S.; Parmentier, R.; Bridges, I. E.; Figiel, S.; Zekri, Y.; Hester, J.; Leach, D.; Bevan, C. L.; Lamb, A. D.; Zwart, W.; Chatziioannou, A.; Le Magnen, C.; Mills, I. G.
10.1101/2025.03.13.643042 — cancer biology — Posted on 2025-06-02
693 Genomic and Phenotypic Characterization of Mupirocin Resistant Staphylococcus aureus Clinical Isolates
Virgillio, A. M.; Felton, E. A.; Jackson, J. K.; Kennedy, S. J.; Becker, D. N.; Lima, A.; Atrubin, K.; Cella, E.; Azarian, T.; Silbert, S.; Shaw, L. N.; Kim, K.
10.1101/2025.04.16.648996 — microbiology — Posted on 2025-06-02
695 Chorionic Gonadotropin Beta 7 is a marker of immune evasion in cancer
McKellar, S. A.; Pineda, J. M. B.; Lattupally, R.; Codd, A. S.; Newell, E.; Lu, S. X.; Bradley, R. K.
10.1101/2025.05.28.656535 — cancer biology — Posted on 2025-06-02
697 A NEW DYSTROPHIN DEFICIENT RAT MODEL MIRRORING EXON SKIPPING IN PATIENTS WITH DMD EXON 45 DELETIONS
JABER, A.; WANG, T.; DAOUD, C.; ALBINI, S.; CORRE, G.; BELLEC, J.; BOVOLENTA, M.; DORVAL, A.; DUBOIS, A.; PHILIDET, L.; WARTHI, G.; RICHARD, I.
10.1101/2025.05.30.656540 — genetics — Posted on 2025-06-02
698 Viral adsorption to Moore swabs in passive wastewater sampling
Rao, G.; Purvis, T.; Cha, G.; Dalton, J.; Fisher, M.; Graham, K. E.; Konstantinidis, K. T.; Linden, Y.; Bivins, A.; Brinton, M. A.; Stauber, C.; Brown, J.
10.1101/2025.05.30.656954 — microbiology — Posted on 2025-06-02
699 Lack of functional STING modulates immunity but does not protect dopaminergic neurons in the alpha-synuclein preformed fibrils Parkinson's Disease mouse model
Klaestrup, I. H.; Reinert, L. S.; Ferreira, S. A.; Lauritsen, J.; Toft, G. U.; Gram, H.; Jensen, P. H.; Paludan, S. R.; Romero-Ramos, M.
10.1101/2025.05.30.656977 — neuroscience — Posted on 2025-06-02
700 Slow-Timescale Regulation of Dopamine Release and Mating Drive over Days
Sunkavalli, P. S.; Madara, J. C.; Christenson, L. F.; Diaz, A.; Chen, J.; Ravotto, L.; Patriarchi, T.; Andermann, M. L.; Zhang, S. X.
10.1101/2025.05.29.656898 — neuroscience — Posted on 2025-06-02
701 Shared and distinct microRNA profiles between HT22, N2A and SH-SY5Y cell lines and primary mouse hippocampal neurons
Jimenez Mateos, E. M.; Murphy, R.; Villegas-Salmeron, J.; Sanz-Rodriguez, A.; Engel, T.; Mooney, C.; Henshall, D. C.
10.1101/2025.06.01.657291 — neuroscience — Posted on 2025-06-02
702 Genotype-Specific Electroretinogram Signatures in Drosophila: Implications for Neurodegeneration Models Using w1118 Backgrounds
Manuel, N.; Mallipudi, M.; Gajwani, A.; Gopalkrishna Shetty Sreenivasa Murthy, S.; Jupiter, D. C.; Krishnan, B.
10.1101/2024.11.29.626125 — neuroscience — Posted on 2025-06-02
703 Adverse prognosis of GM-CSF expression in human cutaneous melanoma
Garcia-Martinez, E.; Nieto-Valle, A.; Barrio-Alonso, C.; Lopez-Navarro, B.; Aviles-Izquierdo, J. A.; Parra-Blanco, V.; Gutierrez-Seijo, A.; Sanchez-Mateos, P.; Samaniego Garcia, R.
10.1101/2025.05.30.656980 — cancer biology — Posted on 2025-06-02
705 Effect of Chronic Stress on Whole Blood Transcriptome: A Meta-Analysis of Publicly Available Datasets from Rodent Models
Flandreau, E. I.; Nguyen, D. M.; Hagenauer, M. H.; Nguyen, M.; Kim, H.; Duan, T.; Bader, A.; Watson, S.; Akil, H.
10.1101/2025.05.30.657043 — genomics — Posted on 2025-06-01
706 Non-canonical enhancers control gene expression and cell fate in human pluripotent stem cells
Cao, Y.; Dovgusha, O.; Ebrahimi, A.; Bevan, S.; Widmer, L.; Torabi, F.; Kurlovich, J.; Rodriguez-Polo, I.; Khan, S.; Patel, M.; Pradeepa, M. M.; Guenesdogan, U.; Schoenfelder, S.
10.1101/2025.06.01.657118 — genomics — Posted on 2025-06-01
712 Nucleus accumbens neuron subtype translatome signatures in socially stress females
Kumar, G.; Franco, D.; Basu, M.; Olusakin, J.; Campbell, R.; Ament, S. A.; Fox, M.; Lobo, M. K.
10.1101/2025.06.01.656319 — neuroscience — Posted on 2025-06-01
713 Uncovering the invisible giant: Amyloid β plaques and their proposed association with waste removal in Alzheimer-affected human hippocampus
Fabian-Fine, R.; Roman, A. G.; Winters, M. J.; Lathram, K. J.; Bennett, C. H.; Kipingi, L. K.; Paul, C. M.; Altman, L. M.; Carrillo, I. C.; Joyce, F. M.; Kragh, L. A.; McKnight, T. J.; Reding, C. J.; Reiderer, L. J.; Rivera, L. J.; Steen, H. A.; Weaver, A. L.
10.1101/2025.06.01.657219 — neuroscience — Posted on 2025-06-01
715 Astrocyte regional specialization is shaped by postnatal development
Schroeder, M. E.; McCormack, D. M.; Metzner, L.; Kang, J.; Li, K. X.; Yu, E.; Melamed, L.; Levandowski, K. M.; Zaniewski, H.; Zhang, Q.; Boyden, E.; Krienen, F. M.; Feng, G.
10.1101/2024.10.11.617802 — neuroscience — Posted on 2025-06-01
716 Correlative light and electron microscopy reveals the fine circuit structure underlying evidence accumulation in larval zebrafish
Boulanger-Weill, J.; Kaempf, F.; Schuhknecht, G. F. P.; Schalek, R. L.; Petkova, M.; Vohra, S. K.; Wu, Y.; Savaliya, J. H.; Tiller, R.; Herrera, K. J.; Naumann, H.; Eberle, M.; Rencken, S.; Stingl, M.; Hebling, A.; Hockling, D.; Slangewal, K.; Deng, Z.; Wang, R. C.; Zhang, L. L.; Kirchberger, K. N.; Bianco, I. H.; Baum, D.; Bene, F. D.; Engert, F.; Lichtman, J. W.; Bahl, A.
10.1101/2025.03.14.643363 — neuroscience — Posted on 2025-06-01
717 Neuronal firing rate diversity lowers the dimension of population covariability
Tian, G. J.; Zhu, O.; Shirhatti, V.; Greenspon, C.; Downey, J. E.; Freedman, D. J.; Doiron, B.
10.1101/2024.08.30.610535 — neuroscience — Posted on 2025-06-01
720 Leveraging autophagy and pyrimidine metabolism to target pancreatic cancer
Dufresne, S.; Kuna, R. S.; Wong, K.; Komarla, A.; Rock, A.; Rosada-Encarnacion, J.; Shen, C.; Mondal, P.; Parham, L. R.; Layng, F. I.; Peck, K. L.; Fowler, A.; Lowy, A. M.; Engle, D.; Tiriac, H.; Shaw, R.; Cosford, N.; Metallo, C.; Towers, C. G.
10.1101/2025.05.29.656904 — cancer biology — Posted on 2025-06-01
726 Structure of a novel contractile injection system in subsp.
Ejaz, R. N.; Funke, K.; Kielkopf, C. S.; Martin, F. J. O.; Siborova, M.; Hendriks, I. A.; Sofos, N. H.; Pape, T. H.; Steiner-Rebrova, E. M.; Nielsen, M. L.; Erhardt, M.; Taylor, N. M. I.
10.1101/2025.06.01.657177 — microbiology — Posted on 2025-06-01
727 Expanding the MR1 ligandome using chemical class-specific fragmentation and molecular networking
Lecchi, C.; Vacchini, A.; Sainas, S.; Lolli, M. L.; Luedtke, M. W.; Mori, L.; De Libero, G.; Balbo, S.; Villalta, P. W.
10.1101/2025.05.29.656472 — immunology — Posted on 2025-06-01
729 Cone bipolar cell synapses generate transient versus sustained signals in parallel ON pathways of the mouse retina
Kuo, S. P.; Yu, W.-Q.; Srivastava, P.; Okawa, H.; Della Santina, L.; Berson, D. M.; Awatramani, G. B.; Wong, R. O.; Rieke, F.
10.1101/2024.05.13.593825 — neuroscience — Posted on 2025-06-01
730 Phase-synchronized 40Hz tACS and iTBS effects on gamma oscillations
Glinski, B.; Salehinehjad, M. A.; Takahashi, K.; Jamil, A.; Yavari, F.; Kuo, M.-F.; Nitsche, M.
10.1101/2025.03.14.643227 — neuroscience — Posted on 2025-06-01
731 EXOSC3 S1-domain variants implicated in PCH1b alter RNA exosome cap subunit abundance and thermal stability disrupting rRNA processing and targeting of AU-rich mRNA
Runnebohm, A. M.; Wijeratne, H. S.; Barron, M. P.; Smith-Kinnaman, W. R.; Rooney, J. D.; Peck Justice, S. A.; Cureton, L. A.; Holland, A.; Ghalei, H.; Pelletier, S.; Doud, E. H.; Vilseck, J. Z.; Mosley, A. L.
10.1101/2025.05.31.657176 — systems biology — Posted on 2025-06-01
732 Voltage-dependent anion channels are mitophagy receptors mediating the recycling of depolarized mitochondria in Arabidopsis
MA, W.; MA, J.; ZHANG, K.; ZHENG, X.; WANG, P.; FENG, L.; MING, S.; ZHUANG, X.; ZHOU, J.; Gao, C.; KANG, B. H.
10.1101/2025.05.29.656919 — plant biology — Posted on 2025-06-01
734 Complement factor D (adipsin) mediates pressure-pain hypersensitivity post destabilization of medial meniscus injury
Tjandra, P. M.; Andoko, B. A.; Kim, J. A.; Gomez, A. G.; Sar, S.; Aepala, M. R.; Pham, T. T. K.; Dumlao, D.; Welhaven, H. D.; Collins, K. H.
10.1101/2025.05.29.656852 — physiology — Posted on 2025-06-01
736 Tumor-specific draining lymph node CD8 T cells orchestrate an anti-tumor response to neoadjuvant PD-1 immune checkpoint blockade
Honigsberg, R.; Cruz, T. D.; Yoffe, L.; Tang, M. S.; Ozgenel, D. O.; Markowitz, G.; Micheal, M.; Singh, A.; Altorki, N. K.; Elemento, O.; Villena-Vargas, J.
10.1101/2025.04.27.650862 — cancer biology — Posted on 2025-06-01
737 MicroCT enables simultaneous longitudinal tracking of murine pancreatic cancer progression and cachexia
Pelz, K. R.; Jimenez, P.; Daniel, C. J.; Newton, S. D.; Cunningham, M.; Sears, R. C.; Worth, P. J.; Brody, J. R.; Zimmers, T. A.
10.1101/2025.05.29.656943 — cancer biology — Posted on 2025-06-01
738 Chemotaxis of branched cells in complex environments
Liu, J.; Ron, J. E.; Rinaldi, G.; Williantarra, I.; Georgantzoglou, A.; de Vries, I.; Sixt, M.; Sarris, M.; Gov, N.
10.1101/2025.05.27.656457 — biophysics — Posted on 2025-06-01
739 Single-molecule FRET and tracking of transfected biomolecules: multi-dimensional protein dynamics in living cells
Anandamurugan, A.; Eidloth, A.; Frank, V.; Wortmann, P.; Schrangl, L.; Lan, C.; Schuetz, G.; Hugel, T.
10.1101/2023.09.15.557875 — biophysics — Posted on 2025-06-01
742 A photostable genetically encoded voltage indicator for imaging neural activities in tissue and live animals
Cao, C.; Zhu, R.; Zhou, S.; Zhao, Z.; Lin, C.; Liu, S.; Peng, L.; Subach, F. V.; Piatkevich, K. D.; Zou, P.
10.1101/2025.05.29.656768 — bioengineering — Posted on 2025-06-01
744 The Na+-pumping mechanism driven by redox reactions in the NADH-quinone oxidoreductase from Vibrio cholerae relies on dynamic conformational changes
Ishikawa-Fukuda, M.; Seki, T.; Kishikawa, J.-i.; Takahiro, M.; Okazaki, K.-i.; Kato, T.; Barquera, B.; Miyoshi, H.; Murai, M.
10.1101/2025.06.01.656757 — biochemistry — Posted on 2025-06-01
749 HIGH CO2 LEVELS OVERCOME THE NIGHTTIME LETHALITY OF CIRCADIAN MUTANTS IN CYANOBACTERIA
Mendana, A.; Santos-Merino, M.; Dominguez-Quintero, M.; Gutierrez-Lanza, R.; Ducat, D.; Fernandez-Lopez, R.
10.1101/2025.06.01.657271 — microbiology — Posted on 2025-06-01
751 IFITM1 and IFITM3 cooperate to restrict virus entry in endolysosomes
Wilt, I.; Jolley, A. A.; Rahman, K.; Lai, K. K.; Shi, G.; Andresson, T.; Compton, A. A.
10.1101/2025.06.01.657267 — microbiology — Posted on 2025-06-01
752 Macrophages Lacking TSC2 have mTORC1-dependent GPNMB Augmentation Ameliorating Cardiac Ischemia-Reperfusion Injury
Keykhaei, M.; Koleini, N.; Meddeb, M.; Tajdini, M.; Rezaee, M.; Huang, Q.; Panesar, T.; Adamo, L.; Ranek, M.; Kass, D. A.
10.1101/2025.05.29.656917 — immunology — Posted on 2025-06-01
754 Developmentally-specific physiological and metabolic responses support drought resilience in switchgrass and constrains biofuel yield
Basyal, B.; Li, X.; Pargulski, V.; Fu, X.; Nightingale, N.; Overmyer, K.; Coon, J.; Zhang, Y.; Benucci, G. M. N.; Last, R.; Sato, T.; Walker, B.
10.1101/2025.05.29.656847 — plant biology — Posted on 2025-06-01
758 Automated registration of spatial expression data scales multimodal integration to large cohorts
Harrigan, C. F.; Lam, C. Y.; Chen, D.; Lai, C.; Bremner, R. F.; Jackson, H. W.; Campbell, K.
10.1101/2025.05.29.656851 — bioinformatics — Posted on 2025-06-01
761 A Temporal Single-Cell Multi-Omics Atlas of Murine Pancreatic Islet Remodeling During Hyperglycaemia Progression
Singh, S.; Pavan, M. K.; Barella, L. F.; Telang, J.; Shree, A.; Agarwal, S.; Goel, A.; Thaleshwar, S. i.; Wess, J.; Zafar, H.; Pydi, S. P.
10.1101/2025.05.29.656754 — genomics — Posted on 2025-06-01
765 Developmental system drift in dorsoventral patterning is linked to transitions to autonomous development in Annelida
Carrillo-Baltodano, A. M.; Haillot, E.; Meha, S. M.; Luqman, I.; Pashaj, A.; Lee, Y.-J.; Lu, T.-M.; Ferrier, D. E. K.; Schneider, S. Q.; Martin-Duran, J. M.
10.1101/2025.05.29.656861 — developmental biology — Posted on 2025-06-01
768 EXTENDING PROTEIN LANGUAGE MODELS TO A VIRAL GENOMIC SCALE USING BIOLOGICALLY INDUCED SPARSE ATTENTION
Dejean, T. L.; Ferrell, B. D.; Sawhney, R.; Harrigan, W.; Polson, S. W.; Wommack, K. E.; Belcaid, M.
10.1101/2025.05.29.656907 — bioinformatics — Posted on 2025-06-01
770 Cell Type Specific Aging Transcriptional Signatures of Human Retina Through Integrated Machine Learning and Single-Cell Transcriptomics
Yang, L.; Lin, S.; Tao, Y.; Pan, Q.; Cai, T.; Ye, Y.; Liu, J.; Zhou, Y.; Shao, Y.; Yi, Q.; Lu, Z. H.; Chen, L.; McKay, G.; Rankin, R.; Li, F.; Meng, W.
10.1101/2025.05.29.656930 — bioinformatics — Posted on 2025-06-01
775 Novel insights into the genome organization of Rhizobiaceae: identification of linear plasmids
Kuzmanovic, N.; Wick, R. R.; Kalita, M.; Pulawska, J.; DiCenzo, G. C.; Hynes, M. F.; Smalla, K.; Babin, D.; Thuenen, T.
10.1101/2025.05.29.656789 — genomics — Posted on 2025-06-01
776 Single-cell Characterization of DNA Hydroxymethylation of the Mouse Brain During Aging
Bai, Y.; Yuan, T.; Ren, L.; Huan, Y.; Yang, F.; Li, Y.; Zhang, A.; Liu, Y.; Tian, T.; Kang, N.; Chen, D.; Xie, X.; Wang, Q.; Chen, W.; Zheng, Y.; Xie, X. S.; Cao, Y.
10.1101/2025.05.29.656780 — genetics — Posted on 2025-06-01
777 From Synthetic to Biological Nitrification Inhibition: Advancing Stabilization of Organic Fertilizers
Vega-Mas, I.; Mancia, A.; Maggetto, L.; Murillo, H.; Debacq, A.; Heinesch, B.; Boland, F.; Krause, H.-M.; Vanderschuren, H.; Thonar, C.
10.1101/2025.05.29.656819 — plant biology — Posted on 2025-06-01
779 Plastimos: a live cell imaging-based framework to study dynamics of EMT-mediated cellular plasticity in breast cancer
Hosseini, H.; Sameri, S.; Das, D.; Materna-Reichelt, S.; Stojanovic Guzvic, N.; Wöhrl, L.; Hoffmann, M.
10.1101/2025.05.28.656591 — bioinformatics — Posted on 2025-06-01
781 Spatial metabolomics reveals persistent localized niche-specific metabolic failure in kidneys following ischemia-reperfusion injury
Rietjens, R. G. J.; Manzato, B.; van den Berg, B. M.; Mahfouz, A.; Giera, M.; Dumas, S. J.; Wang, G.; Rabelink, T. J.
10.1101/2025.05.27.656326 — biochemistry — Posted on 2025-06-01
783 Host adaptation and genome evolution of the broad host range fungal rust pathogen, Austropuccinia psidii
Luo, Z.; Tobias, P.; Singh, L.; Dong, C.; Martino, A. M.; Quecine, M.; Massola Junior, N. S.; Silva, L. C. A.; Li, J.; Singh, S.; Zhang, Z.; Jones, A.; Park, R. F.; Schwessinger, B.; Edwards, R.; Boufleur, T.
10.1101/2025.05.29.656941 — microbiology — Posted on 2025-06-01
784 Peptides alleviate cognitive impairment by inhibiting and disassembling amyloid-beta aggregates in Alzheimer disease
Gao, W.; Gao, B.; Wang, S.; Wu, D.; Mei, P.; Geng, L.; Li, C.; Li, Y.; Liu, X.; Pan, J.; Huang, J.; Deng, Y.; Chen, X.; saiyin, H.; Yu, H.; Li, S.; Zhang, Q.; Xu, B.; Huang, F.; Ming, C.; Wu, H.; Li, J.
10.1101/2025.05.28.656730 — neuroscience — Posted on 2025-06-01
785 Rab2 and Arl8/BORC control retrograde axonal transport of dense core vesicles via Syd/dJIP3/4 and RUFY dynein adaptors
Lund, V. K.; Chirco, A.; Caliari, M.; Larsen, A. H.; Gether, U.; Madsen, K. L.; Wierer, M.; Kjaerulff, O.
10.1101/2025.05.28.656585 — neuroscience — Posted on 2025-06-01
786 EEG reveals how space acts as a late heuristic of time
Doricchi, F.; Scozia, G.; Pinto, M.; Lozito, S.; Lo Presti, S.; Pazzaglia, M.; Silvetti, M.; Lasaponara, S.
10.1101/2025.05.28.656560 — neuroscience — Posted on 2025-06-01
787 Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
Goldsworthy, S.; Fertan, E.; Dyal, P.; Domoney, S.; Livesey, F.; Klenerman, D.; Patani, R.; Hung, C.
10.1101/2025.05.27.656416 — neuroscience — Posted on 2025-06-01
788 Integrin-Specific Signaling Drives ER Stress-Dependent Atherogenic Endothelial Activation
Ben Dhaou, C.; Al-Yafeai, Z.; Cruz-Marquez, G. A.; Scott, M. L.; Pearson-Gallion, B.; Cockerham, E.; Li, H.; Peretik, J. M.; Hong, Y.; Dhanesha, N.; Yurdagul, A.; Rom, O.; Bhuiyan, M. S.; Orr, A. W.
10.1101/2025.05.31.654582 — pathology — Posted on 2025-06-01
789 Population structure of Phytophthora infestans collected from potatoes in Guatemala and Honduras
Izarra, M. L.; Perez, W. G.; Vasquez, E. F.; Perez, G. E.; Gamboa, S.; Andrade-Piedra, J.; Flores, B.; Montejo, L.; Sanders, A.; Kreuze, J. F.
10.1101/2025.05.28.656702 — pathology — Posted on 2025-06-01
790 KODAMA enables self-guided weakly supervised learning in spatial transcriptomics
Abdel-Shafy, E. A.; Kassim, M.; Vignoli, A.; Mamdouh, F.; Tyekucheva, S.; Ahmed, D.; Ojo, D.; Price, B.; Socciarelli, F.; Duarte-Delgado, N. P.; Ocharo, M.; Okeke, C. J.; Triboli, L.; MacIntyre, D. A.; Loda, M.; Sarkar, D.; Gupta, D.; Piazza, S.; Zerbini, L. F.; Tenori, L.; Cacciatore, S.
10.1101/2025.05.28.656544 — bioinformatics — Posted on 2025-06-01
791 The clinical drug candidate anle138b binds predominantly to the central cavity in lipidic Aβ fibrils and modulates fibril formation.
Han, M.; Frieg, B.; Matthes, D.; Leonov, A.; Ryazanov, S.; Giller, K.; Nimerovsky, E.; Stampolaki, M.; Xue, K.; Overkamp, K.; Dienemann, C.; Riedel, D.; Giese, A.; Becker, S.; de Groot, B. L.; Schroeder, G.; Andreas, L. B.; Griesinger, C.
10.1101/2025.05.30.655790 — biochemistry — Posted on 2025-06-01
792 Genomic signatures of climate-driven (mal)adaptation in an iconic conifer, the English yew (Taxus baccata L.)
Francisco, T.; Mayol, M.; Vajana, E.; Riba, M.; Westergren, M.; Cavers, S.; Pinosio, S.; Bagnoli, F.; Marchi, M.; Aravanopoulos, F. A.; Farsakoglou, A.-M.; Scotti, I.; Fady, B.; Vendramin, G. G.; Archambeau, J.; Piotti, A.; Gonzalez-Martinez, S. C.
10.1101/2025.05.29.656833 — genomics — Posted on 2025-06-01
793 The XPF-like domain in SHOC1 required for homologous recombination and safeguarding autosome from meiotic silencing of unsynapsed chromatin
Zhang, Y.; Sun, Q.; Ji, Z.; Mo, R.; Zhou, Y.; Zhao, J.; Xu, S.; Li, N.; Sun, Y.; Bai, H.; Zhi, E.; Han, S.; Chen, H.; Zhang, J.; Qian, D.; Bu, X.; Huang, Y.; Tian, R.; Guo, Y.; Lv, J.; Zhao, L.; Yang, C.; Zhao, F.; Li, P.; Zhou, Z.; Li, Z.; Yao, C.
10.1101/2025.05.28.656576 — developmental biology — Posted on 2025-06-01
796 Recovery of retinal terminal fields after traumatic brain injury: evidence of collateral sprouting and sexual dimorphism
Alexandris, A. S.; Yi, J.; Liu, C.; Belamarich, J.; Alam, Z.; Vats, A.; Peng, A.; Welsbie, D. S.; Zack, D. J.; Koliatsos, V. E.
10.1101/2025.05.28.656451 — neuroscience — Posted on 2025-06-01
799 nanoPhos enables ultra-sensitive and cell-type resolved spatialphosphoproteomics
Oliinyk, D.; Heymann, T.; Henneberg, L.; Bardziukova, A.; Thielert, M.; Kjaergaard, J.; Vasconez, S.; Oeller, M.; Rodriguez, E.; Rosenberger, F. A.; Mann, M.
10.1101/2025.05.29.656770 — systems biology — Posted on 2025-06-01
800 Body Fluid Proteomic Landscape of Acute Exercise
Kurgan, N.; Kjaergaard, J.; Jespersen, N. Z.; Diez-Obrero, V.; Moreno-Justicia, R.; Heywood, S. E.; Lindqvist, C. B.; Ottander, L.; Samodova-Sommer, D.; Nielsen, N. S.; Durrer, C. G.; Ried-Larsen, M.; Rasmussen, S.; Loos, R. J. F.; Smit, R. A. J.; Pedersen, B. K.; Deshmukh, A. S.
10.1101/2025.05.28.656705 — physiology — Posted on 2025-06-01
801 Molecular dynamics driving phenotypic divergence among KRAS mutants in pancreatic tumorigenesis
Grimont, A.; Falvo, D. J.; Sisso, W. J.; Zumbo, P.; Chan, C. W.; Santos, F.; Pan, G.; Cleveland, M.; Yaron, T.; Osterhoudt, A. S.; Meng, Y.; Zafra, M. P.; Fall, W. B.; Rendeiro, A. F.; Hissong, E.; Yantiss, R. K.; Betel, D.; Magnuson, M. A.; Leach, S. D.; Rustgi, A. K.; Dow, L. E.; Chandwani, R.
10.1101/2025.05.28.656689 — cancer biology — Posted on 2025-06-01
802 Robust statistical assessment of Oncogenotype to Organotropism translation in xenografted zebrafish
Saucier, D.; Jiang, X.; Rajendran, D.; Ravishankar, R.; Butler, E.; Marchetto, A.; Kurmasheva, R.; Gruenewald, T.; Amatruda, J.; Danuser, G.
10.1101/2025.05.28.656734 — cancer biology — Posted on 2025-06-01
803 PAMD-Ch17, a Polymeric Analog of Plerixafor, Induces Mitochondrial Dysfunction in T-ALL Cells Independent of CXCR4
Lam, C.; Dhir, A.; Jogdeo, C. M.; Panda, S.; Kapoor, E.; Tang, S.; Rivero, V.; McIntyre, E. M.; Xiao, P.; Black, A. R.; Hewitt, K.; Swenson, S. A.; Romanova, S.; Oupicky, D.; Hyde, R. K.
10.1101/2025.05.28.656643 — cancer biology — Posted on 2025-06-01
805 Targeted suppression of SPP1 inhibits tumor invasion and metastasis in NRF2 hyperactivated cisplatin resistant HNSCC
Kawabe, M.; Yang, S.; Bolanos, L. G.; Takamatsu, S.; Flores, S. A.; Castro, P. D.; Tsai, T.-Y.; Kaga, A. N.; Frederick, M. J.; Sandulache, V.; Kadara, H.; Myers, J. N.; Osman, A. A.
10.1101/2025.05.28.656679 — cancer biology — Posted on 2025-06-01
807 Neural Spectral Prediction for Structure Elucidation with Tandem Mass Spectrometry
Wang, R.; Manjrekar, M.; Mahjour, B.; Avila-Pacheco, J.; Provenzano, J.; Reynolds, E.; Lederbauer, M.; Mashin, E.; Goldman, S. L.; Wang, M.; Weng, J.-K.; Plata, D. L.; Clish, C. B.; Coley, C. W.
10.1101/2025.05.28.656653 — bioinformatics — Posted on 2025-06-01
810 Controllable Gap Junctions by Vitamin B12 and Light
Cui, D.; Liu, S.; Huang, X.; Tang, X. A.; Zheng, M.; He, Z.; Xu, R.; Sun, C.; Xu, Y.; Tu, R.; Zou, P.; Xie, T.; Sun, F.
10.1101/2025.05.28.656405 — bioengineering — Posted on 2025-06-01
814 Projected warming disrupts embryonic development and hatch timing in Antarctic fish
Streeter, M. S.; Le Francois, N. R.; Desvignes, T.; Grondin, J.; Postlethwait, J. H.; Detrich, H. W.; Daane, J.
10.1101/2025.05.28.656708 — developmental biology — Posted on 2025-06-01
816 SUSTAINED SYSTEMIC AND NEUROINFLAMMATION IN COGNITIVE DYSFUNCTIONAL FEMALE MICE AFTER NON-SEVERE EXPERIMENTAL MALARIA
Rosa-Goncalves, P.; Siqueira-e-Silva, B. N.; Lima, M. N.; Chagas, L. d. S.; de-Sousa, L. P.; Caputo, L. F. G.; da Silva, I. J.; dos Santos, J. P. R.; Evaristo, C. C. d. A.; Nogueira, M. d. S.; Werneck, G. L.; Ribeiro-Gomes, F. L.; Totino, P. R. R.; Pratt-Riccio, L. R.; Maron-Gutierrez, T.; de Almeida, R. F.; Machado, M. P.; Serfaty, C. A.; Daniel-Ribeiro, C. T.
10.1101/2025.05.28.656400 — immunology — Posted on 2025-06-01
817 Hair follicle stem cell fate supports distinct clinical endotypes in Hidradenitis Suppurativa
Onfroy, A.; Jean-Louis, F.; Le Corvoisier, P.; Coulpier, F.; Muret, K.; Bonnet, E.; Arrouasse, R.; Boucle, C.; Abid, S.; Sbidian, E.; Bergqvist, C.; Wolkenstein, P.; Godot, V.; Deleuze, J.-F.; Levy, Y.; Topilko, P.; Audureau, E.; Hue, S.
10.1101/2025.05.28.656362 — immunology — Posted on 2025-06-01
818 Microtubule anchoring and coupling of CD20 to the RhoA/Rock1 pathway
Klasener, K.; Lee, C. E.; Bender, J.; Naumann, A.; Reimann, L.; Andrieux, G.; Nitschke, R.; Warscheid, B.; Warnatz, K.; Voll, R. E.; Reth, M.
10.1101/2025.05.29.656301 — immunology — Posted on 2025-06-01
819 Germline polymorphism in the immunoglobulin kappa and lambda loci explain variation in the expressed light chain antibody repertoire
Engelbrecht, E.; Rodriguez, O. L.; Lees, W.; Vanwinkle, Z.; Shields, K.; Schultze, S.; Gibson, W. S.; Smith, D. R.; Jana, U.; Saha, S.; Peres, A.; Yaari, G.; Smith, M. L.; Watson, C. T.
10.1101/2025.05.28.656470 — immunology — Posted on 2025-06-01
821 Protective role of Cannabidiol against nicotine pouch-induced seizure aggravation and alterations in brain glymphatic biomarkers.
Bhandari, B.; Naeini, S. E.; Rogers, H. M.; Alhashim, A. H.; Yu, J. C.; Seyyedi, M.; Young, N.; Salles, E. L.; Wang, L. P.; Baban, B.
10.1101/2025.05.28.656668 — neuroscience — Posted on 2025-06-01
823 Opposing effects of H2A.Z on memory, transcription and pathology in male and female Alzheimer's disease mice and patients
Luo, J. Q.; Hategan, L. A.; Creighton, S.; Hua, S.; McLean, T. A. B.; Dahi, T. A.; Jin, Z.; Pirri, F.; Winston, S. M.; Reeves, I. L.; Fahnestock, M.; Brimble, M. A.; Walters, B. J.; Murphy, P. J.; Zovkic, I.
10.1101/2025.05.28.656659 — neuroscience — Posted on 2025-06-01
824 Pyruvate kinase activates SARM1 to exacerbate axonal degeneration in diabetic peripheral neuropathy
Liu, J.; Li, W.; Li, C.; Jiang, Y.; Zhu, W. J.; Zhang, Z.; Zhao, Y. J.; Lin, J.; YU, W.
10.1101/2025.05.28.656718 — neuroscience — Posted on 2025-06-01
826 Twist and Snout: Head and Body Morphologies Determine Feeding Kinematics in Substrate-Biting Fishes
Perevolotsky, T.; Brotman-Krass, J. M.; Ratner, Y.; Avigad, Y.; Summers, A. P.; Donatelli, C. M.; Holzman, R.
10.1101/2025.05.28.656629 — zoology — Posted on 2025-06-01
827 Integrating Alternative Fragmentation Techniques into Standard LC-MS Workflows Using a Single Deep Learning Model Enhances Proteome Coverage
Levin, N.; Saylan, C. C.; Lapin, J.; Demyanenko, Y.; Yang, K. L.; Sidda, J.; Nesvizhskii, A.; Wilhelm, M.; Mohammed, S.
10.1101/2025.05.28.656555 — systems biology — Posted on 2025-06-01
828 Maternal control of RNA decay safeguards embryo development
Del Toro-De Leon, G.; Trenti, M. S.; Vasudevan, V.; Krause, U.; Köhler, C.
10.1101/2025.05.28.656625 — plant biology — Posted on 2025-06-01
829 Galactan mobilization during carbon starvation compromises cell wall-mediated fungal resistance in Arabidopsis
Reckleben, L.; Morton, R. N.; Munzert-Eberlein, K. S.; Thiel, S.; Rautengarten, C.; Tan, V.; Harres, K. L.; Zanoni, L.; Ebert, B.; Engelsdorf, T.
10.1101/2025.05.28.656597 — plant biology — Posted on 2025-06-01
830 OGDHL regulates nucleotide metabolism, tumor growth, and neuroendocrine marker expression in prostate cancer
Bernard, M.; Ruiz, A.; Diaz, J.; Nunley, N.; Dove, R.; Heering, K.; Bopardikar, S.; Gallardo, A.; Hashimoto, T.; Agrawal, R.; Smith, C.; Wilde, B.; Matulionis, N.; Richards, H.; Sharifi, M.; Lang, J.; Zhao, S.; Haffner, M.; Boutros, P. C.; Christofk, H.; Goldstein, A. S.
10.1101/2025.05.28.656673 — cancer biology — Posted on 2025-06-01
840 Benchmarking Software for DDA-PASEF Immunopeptidomics
Chen, Y.; Preikschat, A.; Arnold, A.; Pecori, R.; Gomez-Zepeda, D.; Tenzer, S.
10.1101/2025.05.28.656277 — bioinformatics — Posted on 2025-06-01
841 Noninvasive Control of Seizure Threshold with Acoustically Targeted Chemogenetics
Li, H.; Nouraein, S.; Lee, S.; Link, S. S.; Raisely, E. K.; Szablowski, J. O.
10.1101/2025.05.28.656723 — bioengineering — Posted on 2025-06-01
842 The SHR/Akr Y chromosome reveals repeated turnover of the rat pseudoautosomal region
Bellott, D. W.; Skaletsky, H.; Hughes, J.; Brown, L. G.; Pyntikova, T.; Cho, T.-J.; Koutseva, N.; Zaghlul, S.; Kizghin, D.; Mendoza, M.; Raudsepp, T.; Dugan, S.; Khan, Z.; Wang, Q.; Watt, J.; Worley, K. C.; Scherer, S.; Muzny, D. M.; Gibbs, R. A.; Page, D. C.
10.1101/2025.05.28.656580 — genomics — Posted on 2025-06-01
843 SMURF Reconstructs Single-Cells from Visium HD Data to Reveal Zonation of Transcriptional Programs in the Intestine
Guo, J.; Sarafinovska, S.; Hagenson, R.; Valentine, M.; Dougherty, J.; Mitra, R. D.; Muegge, B. D.
10.1101/2025.05.28.656357 — genomics — Posted on 2025-06-01
846 Viruses and vectors tied to honey bee colony losses
Lamas, Z.; Rinkevich, F.; Garavito, A.; Shaulis, A.; Boncristiani, D.; Hill, E.; Chen, Y. P.; Evans, J. D.
10.1101/2025.05.28.656706 — ecology — Posted on 2025-06-01
848 Beneficial and detrimental consequences of AHR activation in intestinal infection
Diaz, O. P.; zhou, L.; Barrington, C.; Lindquist, D.; Graelmann, F.; Wincent, E.; Stockinger, B.
10.1101/2025.05.28.656570 — immunology — Posted on 2025-06-01
849 Mind the Gap: Does Brain Age Improve Alzheimer's Disease Prediction?
Tan, T. W. K.; Nguyen, K.-N.; Zhang, C.; Kong, R.; Cheng, S. F.; Ji, F.; Chong, J. S. X.; Chong, E. J. Y.; Venketasubramanian, N.; Orban, C.; Chee, M. W. L.; Chen, C.; Zhou, J. H.; Yeo, B. T. T.; Alzheimer's Disease Neuroimaging Initiative, ; Australian Imaging Biomarkers and Lifestyle Study of Aging,
10.1101/2024.11.16.623903 — neuroscience — Posted on 2025-06-01
850 A Movement-Independent Signature of Urgency During Human Perceptual Decision Making
McCone, H.; Devine, C. A.; McNickle, E.; Dully, J.; Geuzebroek, A. C.; McGovern, D. P.; Kelly, S. P.; O'Connell, R. G.
10.1101/2025.05.28.656559 — neuroscience — Posted on 2025-06-01
851 Movement sonification during haptic exploration shifts emotional outcome without altering texture perception
Mouchnino, L.; Cornuault, P.-H.; Faucheu, J.; Witt, A.; Sutter, C.; Weiland, B.; Blouin, J.; Massi, F.; Chatelet, E.; Danna, J.
10.1101/2025.05.28.656569 — neuroscience — Posted on 2025-06-01
854 Antibiotic resistance genes detected in lichens: insights from Cladonia stellaris
Alonso-Garcia, M.; George, P. B. L.; Leclerc, S.; Veillette, M.; Duchaine, C.; Villarreal, J. C.
10.1101/2025.05.28.656581 — plant biology — Posted on 2025-06-01
855 Stochastic gates for covariate selection in population pharmacokinetics modelling
Kekic, M.; Stepanov, O.; Wang, W.; Richardson, S.; Olabode, D.; Traynor, C.; Dearden, R.; Zhou, D.; Tang, W.; Gibbs, M.; Nowojewski, A.
10.1101/2025.05.28.656586 — pharmacology and toxicology — Posted on 2025-06-01
856 Membrane Interfacial Potential Governs Surface Condensation and Fibrillation of α-Synuclein in Neurons
Shaikh, J.; Nagarajan, A.; Mitra, T.; Modak, A. S.; Biswas, K.; Meher, G.; Bhausaheb, A. J.; Kannan, N. A.; Sahu, B. S.; Ghatak, S.; Choubey, S.; Saleem, M.
10.1101/2025.05.30.657012 — biophysics — Posted on 2025-06-01
857 Cell attachment and tail contraction of S. aureus phage phi812
Binovsky, J.; Siborova, M.; Novacek, J.; Bardy, P.; Baska, R.; Skubnik, K.; Botka, T.; Benesik, M.; Pantucek, R.; Tripsianes, K.; Plevka, P.
10.1101/2024.09.19.613683 — microbiology — Posted on 2025-06-01
859 Motor impairment and adaptation in a novel non-human primate model of internal capsule infarct
Sivakumar, S. S.; Anand, S. A.; Brawer, L.; Mellor, R. L.; Burkhalter, A.; Burton, H.; Brunner, P.; Bundy, D. T.; Leuthardt, E. C.; Moran, D. W.
10.1101/2025.05.27.656471 — neuroscience — Posted on 2025-06-01
860 Reduced susceptibility to experimentally-induced complex visual hallucinations with age
Shenyan, O.; Haye, L.; Milne, G. A.; Lisi, M.; Greenwood, J. A.; Skipper, J. I.; Dekker, T. M.
10.1101/2025.05.27.656359 — neuroscience — Posted on 2025-06-01
862 KODA: Agentic Framework for Microbiome Drug Target Discovery
Aminian-Dehkordi, J.; Parsa, M. S.; Naghipourfar, M.; Mofrad, M.
10.1101/2025.05.27.656480 — bioinformatics — Posted on 2025-06-01
864 Application of Spectral Domain Optical Coherence Tomography To Guide Cochlear Implant Electrode Array
Jiramongkolchai, P.; Amaral, M. M.; Paul, R.; Matt, A.; Nie, M.; Hao, S.; Adkins, A.; Liang, H.; Holden, T.; Buchman, C.; Zhou, C.
10.1101/2025.05.27.656464 — bioengineering — Posted on 2025-06-01
867 Vascular endothelial growth factor receptors 1 and 3 mediate placental trophoblast leptin production in preeclampsia, inducing vascular dysfunction
Elgazzaz, M.; Ogbi, S.; Moronge, D.; Mellott, E.; Cooper, G.; Backer, K.; Hitchings, J.; Zarate, L. V.; Kavuri, S.; Lee, T. J.; Ilatovskaya, D.; Woodham, P. C.; Maher, J.; Annex, B. H.; Faulkner, J. L.
10.1101/2025.05.27.656489 — physiology — Posted on 2025-06-01
869 Rules of engagement: determinants of chemokine receptor activation and selectivity by CCL27 and CCL28
Huang, M.; Celniker, A. F.; Chitsazi, R.; Dyer, D. P.; Jansma, A. L.; Kufareva, I.; Salanga, C. L.; Handel, T.
10.1101/2025.05.27.656466 — pharmacology and toxicology — Posted on 2025-06-01
870 In-Silico Characterization of TP53 Splice Mutations in Somatic and Germline Tumours
Bhandarkar, A. A.; Kelly-Foleni, N. E.; Sarkar, D.; Jeffs, A.; Slatter, T.; Braithwaite, A.; Mehta, S.
10.1101/2025.05.27.656522 — cancer biology — Posted on 2025-06-01
871 Engineering Sustained-Release Broadly Neutralizing Antibody Formulations
Jons, C. K.; Kasse, C. M.; Mayer, B. T.; Hyrien, O.; Sen, S.; Meany, E. L.; d'Aquino, A. I.; Ganesh, P.; Eckman, N.; Dong, C.; Yan, J.; Nguyen, L. T.; Doulames, V. M.; Song, Y. E.; Saouaf, O. M.; Williams, C. M.; Williams, S. C.; Paredes, J.; Raghavan, R.; Palomares, M.; Alpert, M.; Yates, N. L.; Tomaras, G.; Seaman, M. S.; Farzan, M.; Appel, E. A.
10.1101/2025.05.27.656504 — bioengineering — Posted on 2025-06-01
872 Female cortical cellular mosaicism underlies shared MeCP2 and PCB impacted gene pathways
Sharifi, O.; Neier, K. E.; Valenzuela, A. E.; Torres, C. G.; Korf, I.; Lein, P. J.; Yasui, D. H.; LaSalle, J.
10.1101/2025.05.28.655836 — systems biology — Posted on 2025-06-01
874 Ketogenesis is dispensable for the metabolic adaptations to caloric restriction
Yeh, C.-Y.; Borgelt, L.; Vogt, B. J.; Clark, A. A.; Wong, T. T.; Grunow, I.; Sonsalla, M. M.; Babygirija, R.; Liu, Y.; Trautman, M. E.; Calubag, M. F.; Knopf, B. A.; Xiao, F.; Lamming, D.
10.1101/2025.05.29.656153 — physiology — Posted on 2025-06-01
875 Multiscale Modeling Uncovers Macrophage Infiltration and TNF-α Signaling Networks for Targeting in Inflammatory Breast Cancer Tumor Emboli
PAI, P.; Van Berckelaer, C.; Van Laere, S.; Bennion, A.; Charity, T.; Yang, J.; Bertucci, F.; Van Dam, P.; Palmer, G. M.; McCall, S.; Dirix, L. Y.; Ueno, N. T.; Devi, G.
10.1101/2025.05.29.656249 — cancer biology — Posted on 2025-06-01
876 Inter-tool analysis of a NIST dataset for assessing baseline nucleic acid sequence screening
Laird, T. S.; Flyangolts, K.; Bartling, C.; Gemler, B. T.; Beal, J.; Mitchell, T.; Murphy, S. T.; Berlips, J.; Foner, L.; Doughty, R.; Quintana, F.; Nute, M.; Treangen, T. J.; Godbold, G.; Ternus, K.; Alexanian, T.; Wheeler, N.; Forry, S. P.
10.1101/2025.05.30.655379 — bioinformatics — Posted on 2025-06-01
878 Visualizing the Chronicle of Multiple Cell Fate using a Near-IR Dual-RNA/DNA-Targeting Probe
Sutrisno, L.; Richards, G. J.; Evans, J. D.; Matsumoto, M.; Li, X.; Uto, K.; Hill, J. P.; Taki, M.; Yamaguchi, S.; Ariga, K.
10.1101/2025.05.29.655717 — bioengineering — Posted on 2025-06-01
882 The Kocurious case of Noodlococcus: genomic insights into Kocuria rhizophila from characterisation of a laboratory contaminant
McCallum, G. E.; Ho, S. F. S.; Cummins, E. A.; Wildsmith, A. J.; McInnes, R. S.; Weigel, C.; Tong, L. Y. S.; Quick, J.; van Schaik, W.; Moran, R. A.
10.1101/2025.05.28.656266 — genomics — Posted on 2025-06-01
884 KLHL41 orchestrates sarcomere assembly and size to drive skeletal muscle hypertrophy in vivo
Han, H.; Shi, J.; Bongiorno, A. H.; Mansur, A.; Widrick, J.; Tate, G.; Gill, S.; Karimi, E.; Granzier, H.; Moore, J. R.; Gupta, V. A.
10.1101/2025.05.30.655367 — genetics — Posted on 2025-06-01
885 A primate model organism for cardiac arrhythmias identifies a magnesium transporter in pacemaker function
Chang, S.; Karanewsky, C. J.; Pendleton, J. L.; Ren, L.; Anzeraey, A.; Froelicher, V.; Liang, D.; Razafindrakoto, A.; Ravelonjanahary, H. N.; Albertelli, M. A.; Quertermous, T.; Wright, P. C.; Perret, M.; Terrien, J.; Aujard, F.; Wu, J. C.; Krasnow, M. A.
10.1101/2025.05.28.655959 — genetics — Posted on 2025-06-01
887 Rational design of respiratory syncytial virus dimeric F-subunit vaccines in protein and mRNA forms
Li, J.; Ma, X.; Xu, Z.; Guo, W.; Peng, R.; zhang, Y.; Meng, Y.; Wang, Q.; Li, S.; Chen, J.; Guo, Y.; Lu, X.; Wang, Q.; Guo, Y.; Jia, M.-a.; Li, Y.; Zhang, Y.; Li, S.; Du, P.; Wang, Q.; Gao, G. F.; Qi, J.
10.1101/2025.05.31.655981 — immunology — Posted on 2025-06-01
888 Characterising Structural Brain Connectivity of Patients with First Episode of Psychosis
Sanchez, S. M.; Knösche, T.; Fürstova, P.; Skoch, A.; Spaniel, F.; Schmidt, H.; Hlinka, J.
10.1101/2025.05.30.656096 — neuroscience — Posted on 2025-06-01
889 Dexmedetomidine produces more sleep-like brain activity compared to propofol
Krause, B. M.; Dappen, E. R.; Mueller, R. N.; Kawasaki, H.; Sanders, R. D.; Nourski, K. V.; Banks, M. I.
10.1101/2025.05.27.656383 — neuroscience — Posted on 2025-06-01
890 Four-dimensional neural space for moral inference
Chen, J.; Santavirta, S.; Putkinen, V. J.; Boggio, P.; Nummenmaa, L.
10.1101/2025.05.28.656268 — neuroscience — Posted on 2025-06-01
892 An atlas of TF driven gene programs across human cells
Pett, J. P.; Prete, M.; Pham, D.; England, N.; Yuan, H.; Prigmore, E.; Tuck, L.; Oszlanczi, A.; To, K.; Xu, C.; Suo, C.; Dann, E.; He, P.; Kedlian, V. R.; Kanemaru, K.; Cranley, J.; Yang, L.; Elmentaite, R.; Oliver, A. J.; Cujba, A.-M.; Cakir, B.; Murray, S.; Mahbubani, K. T.; Saeb-Parsy, K.; Gambardella, L.; Kasper, M.; Haniffa, M. A.; Nawijn, M. C.; Teichmann, S. A.; Meyer, K. B.
10.1101/2025.05.30.657075 — genetics — Posted on 2025-06-01
893 Making new connections: An fNIRS machine learning classification study of neural synchrony in the default mode network
Miao, G. Q.; Lieberman, I. J.; Binnquist, A. L.; Pluta, A.; Goldstein, B. M.; Dale, R.; Lieberman, M. D.
10.1101/2025.05.31.656874 — neuroscience — Posted on 2025-06-01
894 Encoding of speech modes and loudness in ventral precentral gyrus
Srinivasan, A.; Wairagkar, M.; Iacobacci, C.; Hou, X.; Card, N. S.; Jacques, B. G.; Pritchard, A. L.; Bechefsky, P. H.; Hochberg, L. R.; AuYong, N.; Pandarinath, C.; Brandman, D. M.; Stavisky, S. D.
10.1101/2025.05.30.657105 — neuroscience — Posted on 2025-06-01
895 From Morphology to Computation: How Synaptic Organization Shapes Place Fields in CA1 Pyramidal Neurons
Tasciotti, S.; Iascone, D. M.; Chavlis, S.; Hammond, L.; Katz, Y.; Losonczy, A.; Polleaux, F.; Poirazi, P.
10.1101/2025.05.30.657022 — neuroscience — Posted on 2025-06-01
896 Pupil responses to social stimuli are associated with adaptive behaviors across the first 24 months of life
Grzadzinski, R.; Carpenter, R. S.; Rutshon, J.; Jatkar, A.; Mata, K.; Bhatt, A.; Ortiz-Juza, M. M.; Dennehey, M. R.; Gilleskie, D. B.; Ellison, J.; Pegard, N.; Rodriguez-Romaguera, J.
10.1101/2025.05.30.656675 — physiology — Posted on 2025-06-01
897 Cell-type-specific patterns and consequences of somatic mutation in development and aging brain
Kriz, A. J.; Mao, S.; Shao, D. D.; Snellings, D. A.; Andersen, R.; Dong, G.; Ma, C. C.; Cline, H. E.; Huang, A. Y.; Lee, E. A.; Walsh, C. A.
10.1101/2025.05.30.656844 — genomics — Posted on 2025-06-01
898 Transplantation of GABAergic Interneuron Progenitors Restores Cortical Circuit Function in an Alzheimer's Disease Mouse Model
Yokomizo, S.; Maci, M.; Stafford, A. M.; Miller, M. R.; Perle, S. J.; Takahashi, S.; Brown-Harding, H.; Liang, L.; Lovely, A.; Algamal, M.; Gillani, R. L.; Zwang, T. J.; Richardson, D.; Naegele, J. R.; Vogt, D.; Kastanenka, K. V.
10.1101/2025.05.31.656412 — neuroscience — Posted on 2025-06-01
899 The mGluR5 Agonist, CHPG, Enhances Numbers of Differentiated Human Oligodendrocytes
Huang, Y.; Geywitz, C.; Bandaru, A.; Glass, I.; Birth Defects Research Laboratory, ; Schirmer, L.; Nobuta, H.; Dreyfus, C.
10.1101/2025.05.31.656838 — neuroscience — Posted on 2025-06-01