Channel:  Francis Crick Institute

1,182 Articles

A conserved role of Hippo signaling in initiation of the first lineage specification event across mammals
Gerri, C., McCarthy, A., Scott, G. M., Regin, M., Brumm, S., Simon, C. S., Lee, J., Montesinos, C., Hassitt, C., Hockenhull, S., Hampshire, D., Elder, K., Snell, P., Christie, L., Fouladi-Nashta, A. A., Van de Velde, H., Niakan, K.
10.1101/2022.07.01.498418 — Posted: 2022-07-02
RNA polymerase II dynamics and mRNA stability feedback determine mRNA scaling with cell size
Swaffer, M. P., Marinov, G. K., Zheng, H., Yee Tsui, C., Jones, A. W., Kundaje, A., Greenleaf, W. J., Reyes-Lamothe, R., Skotheim, J. M.
10.1101/2021.09.20.461005 — Posted: 2022-07-01
Craniofacial dysmorphology in Down Syndrome is caused by increased dosage of Dyrk1a and at least three other genes
Redhead, Y., Gibbins, D., Lana-Elola, E., Watson-Scales, S., Dobson, L., Krause, M., Liu, K., Fisher, E., Green, J., Tybulewicz, V.
10.1101/2022.06.27.497841 — Posted: 2022-06-28
Comprehensive Analysis of CRISPR Base Editing Outcomes for Multimeric Protein
Kabra, M., Moosajee, M., Newby, G., Molugu, K., Saha, K., Liu, D., Pattnaik, B. R.
10.1101/2022.06.20.496792 — Posted: 2022-06-20
A computationally-enhanced hiCLIP atlas reveals Staufen1 RNA binding features and links 3' UTR structure to RNA metabolism
Chakrabarti, A. M., Iosub, I. A., Lee, F. C. Y., Ule, J., Luscombe, N. M.
10.1101/2022.06.13.495933 — Posted: 2022-06-16
Modelling mitosis with multiple phenotypes: relation to Haeckel's recapitulation law
Alexandrov, Y.
10.1101/253203 — Posted: 2022-06-15
Crowd-sourced benchmarking of single-sample tumour subclonal reconstruction
Salcedo, A., Tarabichi, M., Buchanan, A., Espiritu, S. M. G., Zhang, H., Zhu, K., Yang, T.-H. O., Leshchiner, I., Anastassiou, D., Guan, Y., Jang, G. H., Haase, K., Deshwar, A. G., Zou, W., Umar, I., Dentro, S., Wintersinger, J. A., Chiotti, K., Demeulemeester, J., Jolly, C., Scyza, L., Ko, M., PCAWG-11 Working Group, , SMC-Het Participants, , Wedge, D. C., Morris, Q. D., Ellrot, K., Van Loo, P., Boutros, P. C.
10.1101/2022.06.14.495937 — Posted: 2022-06-15
Genome-wide functional analysis reveals key roles for kinesins in the mammalian and mosquito stages of the malaria parasite life cycle
Zeeshan, M., Rashpa, R., Ferguson, D. J. P., Abel, S., Chahine, Z., Brady, D., vaughan, s., Moores, C. A., Le Roch, K. G., Brochet, M., Holder, A. A., Tewari, R.
10.1101/2021.05.26.445751 — Posted: 2022-06-15
A choline-releasing glycerophosphodiesterase essential for phosphatidylcholine biosynthesis and blood stage development in the malaria parasite
Ramaprasad, A., Burda, P.-C., Calvani, E., Sait, A., Palma-Duran, S. A., Withers-Martinez, C., Hackett, F., MacRae, J. I., Collinson, L., Gilberger, T., Blackman, M.
10.1101/2022.06.14.496138 — Posted: 2022-06-14
Inhibition of vaccinia virus L1 N-myristoylation by the host N-myristoyltransferase inhibitor IMP-1088 generates non-infectious virions defective in cell entry
Priyamvada, L., Kallemeijn, W. W., Faronato, M., Wilkins, K., Goldsmith, C. S., Cotter, C. A., Ojeda, S., Solari, R., Moss, B., Tate, E. W., Satheshkumar, P. S.
10.1101/2022.06.13.495866 — Posted: 2022-06-13

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