Channel:  Francis Crick Institute

1,153 Articles

Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
Tomic, G., Sheridan, C., Refermat, A. Y., Baggelaar, M. P., Sipthorp, J., Sudarshan, B., Ocasio, C. A., Suarez-Bonnet, A., Priestnall, S. L., Herbert, E., Tate, E. W., Downward, J.
10.1101/2023.02.08.527637 — Posted: 2023-02-09
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Sampedro-Castaneda, M., Baltussen, L. L., Lopes, A. T., Qiu, Y., Sirvio, L., Mihaylov, S. R., Claxton, S., Richardson, J. C., Lignani, G., Ultanir, S. K.
10.1101/2022.11.24.517538 — Posted: 2023-02-08
Targeted cancer therapy induces APOBEC fuelling the evolution of drug resistance
Caswell, D. R., Mayekar, M. K., Gui, P., Law, E. K., Vokes, N. I., Ruiz, C. M., Dietzen, M., Angelova, M., Bailey, C., Pich, O., Bakker, B., Wu, W., Humpton, T. J., Kerr, D. L., Hill, W., Lu, W.-T., Haderk, F., Blakely, C. M., Bakir, M. A., Nagano, A., Gimeno-Valiente, F., Weeden, C., Rowan, A., McCoach, C. E., Almeida, B., Green, M., Gomez, C., Gini, B., Nanjo, S., Barbosa, D., Moore, C., Przewrocka, J., Gronroos, E., Priestnall, S., Suarez-Bonnet, A., Zverev, C., Lighterness, S., Cormack, J., Olivas, V., Cech, L., Rule, B., Ashford, P., Durfee, C., Temiz, N. A., Tan, L., Larson, L. K., Argyr
10.1101/2020.12.18.423280 — Posted: 2023-02-05
A chemoproteomic platform for reactive fragment profiling against the deubiquitinases
Cookson, R., Vuorinen, A., Pettinger, J., Kennedy, C. R., Kirkpatrick, J. M., Peltier-Heap, R. E., Powell, A., Snijders, A. P., Skehel, M., House, D., Rittinger, K., Bush, J. T.
10.1101/2023.02.01.526632 — Posted: 2023-02-03
PerTurboID: A targeted in situ method to measure changes in a local protein environment reveals the impact of kinase deletion on cytoadhesion in malaria causing parasites
Davies, H., Belda, H., Broncel, M., Dalimot, J., Treeck, M.
10.1101/2023.02.02.526785 — Posted: 2023-02-03
Imprinted anti-hemagglutinin and anti-neuraminidase antibody responses after childhood infections of A(H1N1) and A(H1N1)pdm09 influenza viruses
Daulagala, P., Mann, B., Leung, K., Lau, E., Yung, L., Lei, R., Nizami, S. I. N., Wu, J. T., Chiu, S. S., Daniels, R. S., Wu, N. C., Wentworth, D. E., Peiris, J. S. M., Yen, H.-L.
10.1101/2023.02.01.526741 — Posted: 2023-02-02
Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation, and chromosome segregation of sexual transmission stages
Zeeshan, M., Rea, E., Abel, S., Vukusic, K., Markus, R., Brady, D., Eze, A. A., Rashpa, R., Balestra, A., Bottrill, A., Brochet, M., Guttery, D., Tolic, I. M., Holder, A. A., Le Roch, K. G., Tromer, E., Tewari, R.
10.1101/2023.01.29.526106 — Posted: 2023-01-31
Extracellular vesicles and co-isolated endogenous retroviruses differently affect dendritic cells
Cocozza, F., martin jaular, l., lippens, l., di cicco, a., arribas, y. a., dingli, f., richard, m., merle, l., Poullet, P., loew, d., Hendrix, A., Kassiotis, G., joliot, a., tkach, m., Thery, C.
10.1101/2023.01.27.525863 — Posted: 2023-01-28
Phenotyping of lymphoproliferative tumours generated in xenografts of non-small cell lung cancer
Pearce, D. R., Akarca, A. U., De Maeyer, R. P. H., Kostina, E., Huebner, A., Sivakumar, M., Karasaki, T., Shah, K., Janes, S. M., McGranahan, N. E., Reddy, V., Akbar, A., Moore, D. A., Marafioti, T., Swanton, C., Hynds, R. E.
10.1101/2023.01.24.520089 — Posted: 2023-01-24
Mechanistic insights into the interactions between cancer drivers and the tumour immune microenvironment
Misetic, H., Keddar, M. R., Jeannon, J.-P., Ciccarelli, F. D.
10.1101/2023.01.24.525325 — Posted: 2023-01-24

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