COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,198 Articles (22,713 medRxiv, 8,485 bioRxiv)

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Investigation of anti-SARS CoV-2 multimeric bicyclic peptide inhibitors in a range of pre-clinical therapeutic settings
Harman, M. A. J., Gaynor, K. U., Papa, G., Pellegrino, S., Bezerra, G. A., McGuinness, B., Jeffrey, P., Beswick, P., Stanway, S., van Rietschoten, K., Chen, L., Drulyte, I., Herriott, J., Kijak, E., Gallardo Toledo, E., Tatham, L., Sharma, P., Bentley, E., Sharp, J., Kirby, A., Owen, A., Stewart, J. P., Skynner, M. J.
10.1101/2025.10.03.680220 — Posted: 2025-10-05
Oral Microbiota Composition in Children and Adults During Spanish COVID-19 Lockdown: Impact of Home Self-Confinement and SARS-CoV-2 infection
Blanco-Fuertes, M., Gonzalez-Colomino, G., Brotons, P., Lluansi, A., Varo, R., Henares, D., Launes, C., Cisneros, M., F. de Sevilla, M., Garcia-Garcia, J.-J., Mira, A., Bassat, Q., Munoz-Almagro, C.
10.1101/2025.09.30.679491 — Posted: 2025-10-04
Vaccination inequality and social determinants in Brazil during the COVID-19 pandemic
Teixeira, R., Mouta, G. S., Cordeiro, J. S. M., Balieiro, P. C. S., Silva-Neto, A. V., Castro, D. B., Pinto, A. L. C. B., Balieiro, A. A. S., Costa, A. J. L., Sampaio, V. S.
10.1101/2025.10.01.25337110 — Posted: 2025-10-03
Rapid discovery of antiviral targets through dimensionality reduction of genome-scale metabolic models
Lee, Y.-k., Kang, S., Lim, J., Kim, K., Kim, S.-M., Casel, M. A. B., Choi, I., Choi, Y. K., Kim, H. U., Kim, Y.
10.1101/2025.10.02.679942 — Posted: 2025-10-03
Immune Cell Dysfunction of SARS-CoV-2: Mathematical Modeling of the Within-Host Immune Dynamics
Ngoun, P., Alvarez, N., Awad, A., Ryu, H.
10.1101/2025.10.03.680253 — Posted: 2025-10-03
Discovery of rare antigen-specific TCRs via replicate profiling
Egorov, E. S., Kriukova, V. V., Shagina, I. A., Sharonov, G. V., Lupyr, K. R., Staroverov, D. B., Lukyanov, D. K., Salnikova, M. A., Nikolaev, R. N., Shelikhova, L., Lopukhova, G. A., Altunina, A. M., Turchaniniova, M. A., Britanova, O. V., Bryushkova, E. A., Maschan, M. A., Martinez Carrera, L. A., Jelveh, N., Bisdorf, K., Matzke, S. K., Khorkova, S., Bosio, A., Hardt, O., Franke, A., Chudakov, D., Serebrovskaya, E. O.
10.1101/2025.09.30.675572 — Posted: 2025-10-03
Cathepsin K as a Key SARS-CoV-2 Cell Entry Protease and Dual-Inhibition Target
Tabatabaei Dakhili, S. Y., Saha, D., Panwar, P., Mar, E., Hinse, O., Chen, Y. S., Fraser, B. J., Arrowsmith, C., Niikura, M., Van Petegem, F., Bromme, D.
10.1101/2025.10.03.680348 — Posted: 2025-10-03
Neanderthal Introgressed COVID-19 Risk Locus 3p21.31 Under Positive Selection in East Asia via LZTFL1-Driven Ciliary Changes
Pandey, R. K., Desai, S., Chaubey, G.
10.1101/2025.10.01.679818 — Posted: 2025-10-03
PM2.5 Exposure Facilitates SARS-CoV-2 Infection through ACE2/TMPRSS2 Regulation and Suppression of Anti-Viral Response
Rajabi, H., Kayalar, O., Esken, G., Can, F., Bayram, H.
10.1101/2025.10.02.679237 — Posted: 2025-10-03
Computational Analysis of Silent Mutation Effects on SARS-CoV-2 RNA-Host RNA-Binding Protein Interactome
Bello, A. J., Chukwudozie, O. S., Oladapo, O. B., Omotuyi, A. O., Nzoniwu, N. A., Amusa, O. D., Ottu, B. O., Okeke, U., Adewole, A. O., Akinnusi, O. O., Kade, A. E., Minari, J. B., Okpuzor, J., Folarin, O., Shittu, M. O.
10.1101/2025.09.22.677528 — Posted: 2025-10-03

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).