COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,648 Articles (22,913 medRxiv, 8,735 bioRxiv)

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The transmembrane domain regulates the kinetics of the SARS-CoV-2 spike conformational transition
Kulshrestha, A., Banerjee, A., Lall, S., Gosavi, S.
10.64898/2026.04.03.716256 — Posted: 2026-04-03
Machine Learning-Driven Antigen Selection Reveals Conserved T-Cell Targets for Broad Coronavirus Vaccination
Federico, L., Odainic, A., Lund, K. P., Egner, I. M., Wiese, K. E., Cornelissen, L. A. H. M., Kared, H., Stratford, R., Kapell, S., Malone, B., Gheorghe, M., Machart, P., Siarheyeu, R., Tanaka, Y., Clancy, T., Bendjama, K., Munthe, L. A.
10.64898/2026.04.02.716054 — Posted: 2026-04-03
TF-IDF k-mer-based Classical and Hybrid Machine Learning Models for SARS-CoV-2 Variant Classification under Imbalanced Genomic Data
Haque, N., Mazed, A., Ankhi, J. N., Uddin, M. J.
10.64898/2026.04.02.716024 — Posted: 2026-04-02
Conserved stem-loops of the SARS-CoV-2 5'-UTR activate OAS1
Oviedo, A., Bair, C. R., Vasilakopoulos, A. P., Regis, K., VanInsberghe, D., Lowen, A. C., Conn, G. L.
10.64898/2026.04.01.715984 — Posted: 2026-04-02
VYD2311 is a promising candidate for passive immunization against COVID-19 in immunocompromised individuals
Mellis, I. A., Wu, M., Daniel, K., Hong, H., Guo, Y., Ho, D. D.
10.64898/2026.03.31.715419 — Posted: 2026-04-01
Omicron-Enhanced Immunosuppressive Effects of SARS-CoV-2 ORF3a and ORF9b Accessory Proteins on Monocytic Inflammatory Response
Grigas, J., Padilla-Blanco, M., Herran, U. M., Lopez-Ayllon, B. D., Rius, A. d. L., Mendoza Garcia, L., Fernandez Rodriguez, R., Garcia Garcia, T., Garrido, J. J., Pautienius, A., Stankevicius, A., Kucinskaite-Kodze, I., Montoya, M.
10.64898/2026.03.31.715496 — Posted: 2026-04-01
Intranasal immunization with live-attenuated RSV-vectored SARS-CoV-2 vaccines elicits antigen-specific systemic and mucosal immunity and protects against viral challenge and natural infection
Botta, D., Schultz, M. D., Silva-Sanchez, A., Kalange, D., Akther, J., Zhou, F., Tipper, J. L., Yang, G., Schaefers, L. T., Barkley, C. A., Qiu, S., Foote, J. B., Tioni, M. F., Weiss, C. M., Phan, S. I., Green, T. J., Leal, S. M., Harrod, K. S., King, R. G., Moore, M. L., Randall, T. D., Tang, R. S., Lund, F. E.
10.64898/2026.03.30.715311 — Posted: 2026-03-31
Increased Risk of Pulmonary Embolism Following SARS-CoV-2 Activity in Ontario, Canada
Lee, C. E., Wilson, N. J., Fisman, D.
10.64898/2026.03.27.26349516 — Posted: 2026-03-30
Twelve Distinct Laboratory Methods Used to Measure SARS-CoV-2 in Wastewaters throughout a Three-Year Ontario-Wide, Canada Study: Impact on Public Health Interpretation of Disease Incidence
Hegazy, N., Peng, K. K., de Haan-Ward, J., Renouf, E., Mercier, E., Wan, S., Hu, X. J., Dean, C., Servos, M., Edwards, E., Ybazeta, G., Habash, M., Goodridge, L., Brown, R. S., Payne, S. J., Kirkwood, A., Kyle, C., McKay, R. M., Gilbride, K., DeGroot, C., Delatolla, R.
10.64898/2026.03.27.26349524 — Posted: 2026-03-30
Panmap: Scalable phylogeny-guided alignment, genotyping, and placement on pangenomes
Kramer, A. M., Zhang, A., Ayala, N., de Sanctis, B., Karim, L. M., Hinrichs, A. S., Walia, S., Turakhia, Y., Corbett-Detig, R.
10.64898/2026.03.29.711974 — Posted: 2026-03-30

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).