Channel: Human Pangenome Reference Consortium (HPRC)

168 Articles

Lossless Pangenome Indexing Using Tag Arrays

Eskandar, P., Paten, B., Siren, J.

10.1101/2025.05.12.653561 — Posted: 2025-12-05

Efficient near telomere-to-telomere assembly of Nanopore Simplex reads

Cheng, H., Qu, H., McKenzie, S., Lawrence, K. R., Windsor, R., Vella, M., Park, P. J., Li, H.

10.1101/2025.04.14.648685 — Posted: 2025-11-17

Assembling unmapped reads reveals hidden variation in South Asian genomes

Das, A., Biddanda, A., McCoy, R. C., Schatz, M.

10.1101/2025.05.14.653340 — Posted: 2025-10-30

Characterizing cytosine methylation of polymorphic human transposable element insertions using human pangenome resources

Zhuo, X., Tomlinson, C., Belter, E. A., Kuntala, P. K., Saintilnord, W. N., Jiang, J., Lindsay, T., Macias, J., Fulton, R. S., Wang, T.

10.1101/2024.11.22.623804 — Posted: 2025-10-20

map3C: a computational tool for processing multiomic single-cell Hi-C data

Galasso, J., Wang, Y., Alber, F., Ernst, J., Luo, C.

10.1101/2025.10.10.681728 — Posted: 2025-10-15

GECSI: Large-scale chromatin state imputation from gene expression

Fu, J., Ernst, J.

10.1101/2025.10.02.679828 — Posted: 2025-10-04

Integrated ambient modeling and genetic demultiplexing of single-cell RNA+ATAC multiome experiments with Ambimux

Alvarez, M., Li, T., Lee, S. H. T., Arasu, U. T., Selvarajan, I., Örd, T., Rahmani, E., Chen, Z. J., Avram, O., Kar, A., Kaminska, D., Männistö, V., Halperin, E., Pihlajamäki, J., Luo, C., Kaikkonen, M. U., Zaitlen, N., Pajukanta, P.

10.1101/2025.08.21.671671 — Posted: 2025-08-26

Perturb-seq reveals distinct responses to pluripotency regulator dosages underlying the control of self-renewal and differentiation

Yan, J., Cho, H. S., Luo, R., Beer, M. A., Li, W., Huangfu, D.

10.1101/2025.08.07.669196 — Posted: 2025-08-08

ToxiTaRGET: a multi-omics resource for toxicant-responsive molecular targets

Kumar, R., Fu, T., Kuntala, P. K., Fu, S., Li, D., Bartolomei, M. S., Walker, C. L., Wang, T., Zhang, B. A.

10.1101/2025.07.28.667228 — Posted: 2025-08-02

An Efficient Graph Algorithm for Diploid Local Ancestry Inference

Jafarzadeh, N., Eizenga, J. M., Paten, B.

10.1101/2025.07.05.662656 — Posted: 2025-07-09