Channel:  Arc Institute

34 Articles

Structure-guided design of a targeted autoantibody degrader for neurologic disease
Zimanyi, M., Dayao, M., Asencor, A. I., Kondapavulur, S., Asaki, J., McCutcheon, K., Dabaco, C., Bodansky, A., Craik, C., Pleasure, S., DeRisi, J. L., Cheng, Y., Wilson, M., Pluvinage, J. V.
10.64898/2026.02.01.703132 — Posted: 2026-02-03
Genome-wide CRISPRi screen identifies basigin loss as protective in cardiac hypoxia
Flanigan, W. R., Midha, A. D., Blume, S. Y., Marti-Mateos, Y., Costa, M. W., Huang, Y., Baik, A. H., Huynh, H., Susarla, G., Bennett, N. K., Nowak, R. A., Srivastava, D., Nakamura, K., Jain, I. H.
10.64898/2026.01.26.701810 — Posted: 2026-01-27
cyto: ultra high-throughput processing of 10x-flex single cell sequencing
Teyssier, N., Dobin, A.
10.64898/2026.01.21.700936 — Posted: 2026-01-22
Stack: In-Context Learning of Single-Cell Biology
Dong, M., Adduri, A., Gautam, D., Carpenter, C., Shah, R., Ricci-Tam, C., Kluger, Y., Burke, D. P., Roohani, Y. H.
10.64898/2026.01.09.698608 — Posted: 2026-01-09
scBaseCount: an AI agent-curated, uniformly processed, and autonomously updated single cell data repository
Youngblut, N. D., Carpenter, C., Nayebnazar, A., Adduri, A., Shah, R., Ricci-Tam, C., Prashar, J., Ilango, R., Teyssier, N., Konermann, S., Hsu, P., Dobin, A., Burke, D. P., Goodarzi, H., Roohani, Y. H.
10.1101/2025.02.27.640494 — Posted: 2025-11-02
BINSEQ: A Family of High-Performance Binary Formats for Nucleotide Sequences
Teyssier, N., Dobin, A.
10.1101/2025.04.08.647863 — Posted: 2025-10-29
Efficient generation of epitope-targeted de novo antibodies with Germinal
Mille-Fragoso, L. S., Wang, J. N., Driscoll, C. L., Dai, H., Widatalla, T. M., Zhang, X., Hie, B. L., Gao, X. J.
10.1101/2025.09.19.677421 — Posted: 2025-09-25
An image-based CRISPR screen reveals splicing-mediated control of HP1α condensates
Wong, M. M.-K., Zhou, S., Carpenter, C., Valbuena, R., Priyadarshini, M., Arya, A., Rizvi, A., Carswell-Crumpton, C., Wileveau, A., Lopez-Lopez, G., Tycko, J., Yao, D., Spees, K., Maynard, J., Bassik, M. C., Goodarzi, H., Sanulli, S.
10.1101/2025.09.21.676939 — Posted: 2025-09-21
Generative design of novel bacteriophages with genome language models
King, S. H., Driscoll, C. L., Li, D. B., Guo, D., Merchant, A. T., Brixi, G., Wilkinson, M. E., Hie, B. L.
10.1101/2025.09.12.675911 — Posted: 2025-09-17
Predicting cellular responses to perturbation across diverse contexts with STATE
Adduri, A. K., Gautam, D., Bevilacqua, B., Imran, A., Shah, R., Naghipourfar, M., Teyssier, N., Ilango, R., Nagaraj, S., Ricci-Tam, C., Carpenter, C., Subramanyam, V., Winters, A., Dong, M., Tirukkovalur, S., Sullivan, J., Plosky, B. S., Eraslan, B., Youngblut, N. D., Leskovec, J., Gilbert, L. A., Konermann, S., Hsu, P. D., Dobin, A., Burke, D. P., Goodarzi, H., Roohani, Y. H.
10.1101/2025.06.26.661135 — Posted: 2025-07-10

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