Channel:  Impact of Genomic Variation on Function (IGVF)

232 Articles

Integrative epigenomic and functional characterization assay based annotation of regulatory activity across diverse human cell types
Dincer, T. U., Ernst, J.
10.1101/2023.07.14.549056 — Posted: 2023-07-15
Proximity Analysis of Native Proteomes Reveals Interactomes Predictive of Phenotypic Modifiers of Autism and Related Neurodevelopmental Conditions
Gao, Y., Trn, M., Shonai, D., Zhao, J., Soderblom, E. J., Garcia-moreno, S. A., Gersbach, C. A., Wetsel, W. C., Dawson, G., Velmeshev, D., Jiang, Y.-h., Sloofman, L. G., Buxbaum, J., Soderling, S. H.
10.1101/2022.10.06.511211 — Posted: 2023-06-23
Integrating Image and Molecular Profiles for Spatial Transcriptomics Analysis
Jiang, X., Wang, S., Guo, L., Wen, Z., Jia, L., Xu, L., Xiao, G., Li, Q.
10.1101/2023.06.18.545488 — Posted: 2023-06-20
Discovery of Competent Chromatin Regions in Human Embryonic Stem Cells
Pulecio, J., Tayyebi, Z., Liu, D., Wong, W., Luo, R., Damodaran, J. R., Kaplan, S., Cho, H., Yan, J., Murphy, D. J., Rickert, R., Shukla, A., Zhong, A., Gonzalez, F., Yang, D., Li, W., Zhou, T., Apostolou, E., Leslie, C., Huangfu, D.
10.1101/2023.06.14.544990 — Posted: 2023-06-14
Studying stochastic systems biology of the cell with single-cell genomics data
Gorin, G., Vastola, J. J., Pachter, L.
10.1101/2023.05.17.541250 — Posted: 2023-05-29
Characterizing glucokinase variant mechanisms using a multiplexed abundance assay
Gersing, S., Schulze, T. K., Cagiada, M., Stein, A., Roth, F. P., Lindorff-Larsen, K., Hartmann-Petersen, R.
10.1101/2023.05.24.542036 — Posted: 2023-05-24
SLC12A9 is a lysosome-detoxifying ammonium - chloride co-transporter
Levin-Konigsberg, R., Mitra, K., Nigam, A., Spees, K., Hivare, P., Liu, K., Kundaje, A., Krishnan, Y., Bassik, M.
10.1101/2023.05.22.541801 — Posted: 2023-05-22
A mutation rate model at the basepair resolution identifies the mutagenic effect of Polymerase III transcription
Seplyarskiy, V., Lee, D. J., Koch, E. M., Lichtman, J. S., Luan, H. H., Sunyaev, S. R.
10.1101/2022.08.20.504670 — Posted: 2023-05-17
De novo distillation of thermodynamic affinity from deep learning regulatory sequence models of in vivo protein-DNA binding
Alexandari, A. M., Horton, C. A., Shrikumar, A., Shah, N., Li, E., Weilert, M., Pufall, M. A., Zeitlinger, J., Fordyce, P. M., Kundaje, A.
10.1101/2023.05.11.540401 — Posted: 2023-05-11
Biophysical modeling with variational autoencoders for bimodal, single-cell RNA sequencing data
Carilli, M. T., Gorin, G., Choi, Y., Chari, T., Pachter, L.
10.1101/2023.01.13.523995 — Posted: 2023-05-02

RSS  Channel RSS