COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,389 Articles (22,816 medRxiv, 8,573 bioRxiv)

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Natural selection driven by escape from shifting antibody classes shapes SARS-CoV-2 evolution
Hamilton, C., Ghafari, M., Ledda, A., Lythgoe, K., Fraser, C., Ferretti, L.
10.64898/2026.03.19.712895 — Posted: 2026-03-20
An AI-Driven Decision-Support Tool for Triage of COVID-19 Patients Using Respiratory Microbiome Data
Avina-Bravo, E. G., Garcia-Lorenzo, I., Alfaro-Ponce, M., Breton-Deval, L.
10.64898/2026.03.18.712739 — Posted: 2026-03-19
De novo design of therapeutic scFvs and multi-specific engagers from sequence alone
Fujiwara, T., Shimizu, H.
10.64898/2026.03.17.712263 — Posted: 2026-03-18
SARS-CoV-2 virus infection of Peromyscus leucopus demonstrates that infection tolerance is not limited to agents for which deermice are reservoirs
Milovic, A., Gach, J. S., Chatzistamou, I., Olivarria, G. M., Lane, T. E., Forthal, D. N., Barbour, A. G.
10.64898/2026.03.13.711660 — Posted: 2026-03-15
TMEM106B mediates ACE2-independent replication of the SARS-CoV-2 S-E484D variant in airway-derived cell models
Xia, M., Wang, Q., Puray-Chavez, M., LaPak, K., Palakurty, S., Liu, Z., Cornejo Pontelli, M., Hui, S., Fremont, D. H., Diamond, M. S., Whelan, S. P. J., Major, M. B., Goldfarb, D., Kutluay, S. B.
10.64898/2026.03.14.711762 — Posted: 2026-03-15
Identification and Masking of Artefactual and Misleading Within-Host Variants in Deep-Sequencing SARS-CoV-2 Data
Anker, K. M., Hall, M., Evans Pena, R., Kemp, S. A., Clarke, J., Zhao, L., Bonsall, D., Grayson, N., Bashton, M., The COVID-19 Genomics UK (COG-UK) Consortium, , Walker, A. S., Golubchik, T., Lythgoe, K.
10.64898/2026.03.13.711550 — Posted: 2026-03-13
Epistasis and the changing fitness landscapes of SARS-CoV-2
Sesta, L., Neher, R. A.
10.64898/2026.03.12.711354 — Posted: 2026-03-13
Spike Antibody Fc Drives Protection from SARS-CoV-2 Challenge in Macaques
Brady, C., Govender, M., Mellors, J., Tipton, T., Gooch, K., Tomic, A., Carroll, M. W.
10.64898/2026.03.13.711527 — Posted: 2026-03-13
Deep mutational scanning of recent SARS-CoV-2 variants highlights changing amino acid preferences within epistatic hotspot residues
Taylor, A., Starr, T. N.
10.64898/2026.03.11.711006 — Posted: 2026-03-13
Physician-scientist hiring practices at US universities before and after the COVID-19 pandemic
Noch, E. K., Obradovic, A., Jain, S., Kwan, J. M.
10.64898/2026.03.04.26347529 — Posted: 2026-03-12

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).