COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,315 Articles (22,772 medRxiv, 8,543 bioRxiv)

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A stable subgenomic reporter coronavirus enables transcriptional profiling of bystander cells.
Gilbride, C., Hemsley-Taylor, J., Nunes, C., Penn, R., Boot, J., Pieris, N., Tripathy, R., Yang, Z., Hutchinson, M., Platt, O. K., Ulferts, R., Mitter, R., Strom, M., Santos, N. B., Bauer, D. L., Mears, H. V.
10.64898/2026.02.27.708290 — Posted: 2026-03-03
Microbiota-derived extracellular vesicles link intestinal dysbiosis to neuroimmune activation in long COVID
Aranguren, M., Doyon-Laliberte, K., Boncheva, I., Villard, A., Desjardins, A., Darbinian, E., Patel, S., DuSablon, C., Rivera Conde, E., Cabrera Munoz, D., Purchase, L., Piscopo, V. E. C., Alluli, A., Benaliouad, F., Sirois, J., Durcan, T., Masse, C., Mlaga, K. D., Chandrasekaran, P., Poudrier, J., Falcone, E. L.
10.64898/2026.02.28.708602 — Posted: 2026-03-02
Transition from infectivity and immune escape to pure escape as an evolutionary strategy during the COVID-19 pandemic.
Kotzen, B., Gurev, S., Youssef, N., Jaimes, J., Luban, J., Marks, D., Seaman, M., Lemieux, J. E.
10.64898/2026.02.26.706090 — Posted: 2026-02-27
Circadian immunometabolic states impart a temporal response to SARS-CoV-2 spike proteins in mammalian macrophages
Buel, S. M., Balaraman, J., Jankowski, M. S., Hixson, K. K., Gao, Y., Kim, Y.-m., Munoz, N., Kyle, J. E., Lipton, M. S., Nicora, C. D., Piehowski, P. D., Baker, S. E., Hurley, J. M.
10.64898/2026.02.24.707668 — Posted: 2026-02-25
Identification of MED13 and DDX60 as critical host factors for SARS-CoV-2 infections
Kwon, H., Wai, S. T., Michlits, G., Dyczynski, M., Markovic, A., Rocha Berger, A. S. B., JOHN, L., Horn, M., Weber, F., Penninger, J. M., Monteil, V., Mirazimi, A.
10.64898/2026.02.25.707691 — Posted: 2026-02-25
AVE0991, a Mas receptor agonist, increases influenza and COVID-19 severity in vivo.
Wu, M., Sng, J. D. J., Noye, E. C., McCallum, G., Bielefeldt-Ohmann, H., Foo, C. X., Ronacher, K., Chew, K. Y., Short, K. R.
10.64898/2026.02.23.707600 — Posted: 2026-02-24
Genetic Evidence Indicates the Evolutionary Importance of the SARS-CoV-2 ORF9b protein
Hisner, R., Martin, D. P.
10.64898/2026.02.23.707522 — Posted: 2026-02-24
Genomic Evolution of SARS-CoV-2 Delta Variants Pre- and Post-Omicron Emergence using Alignment-free Machine Learning models
Sankar, S., Anandharaman, K., Selvam, P., Jayaraman, A., Jayakumar, D., Sivadoss, R., Esaki Muthu, S., Velu, V., Larsson, M., Balakrishnan, P.
10.64898/2026.02.20.706927 — Posted: 2026-02-23
PFOA induced metabolic and immune perturbations in a SARS-2 infection model
Lanier, D. N., Rowe Haas, D., Uchimiya, M., Jones, C., Johnson, S., Sakamoto, K., Chappel, J. R., Fry, A. N., Leach, F. E., DeWitt, J., Woodlief, T., Gaul, D. A., Baker, E. S., Fernandez, F. M., Tompkins, S. M., Edison, A. S.
10.64898/2026.02.21.707085 — Posted: 2026-02-23
TMPRSS2 reduces antibody recognition of SARS-CoV-2 spike
Cottignies-Calamarte, A., De Cruz, A., Planchais, C., Porrot, F., Krzypow, M., Jungbauer-Groznica, M., Thuillier, E., Wileveau, A., Staropoli, I., Guivel-Benhassine, F., Rosenbaum, P., Fernandez, I., Rey, F. A., Buchrieser, J., Trouillet-Assant, S., Mouquet, H., Schwartz, O., Bruel, T.
10.64898/2026.02.17.706397 — Posted: 2026-02-20

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).