COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,886 Articles (22,568 medRxiv, 8,318 bioRxiv)

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Omicron Spike protein has a positive electrostatic surface that promotes ACE2 recognition and antibody escape
Gan, H. H., Zinno, J., Piano, F., Gunsalus, K.
10.1101/2022.02.13.480261 — Posted: 2022-02-14
SARS-CoV-2 Permissive Glioblastoma Cell Line for High Throughput Antiviral Screening
Vanhulle, E., Stroobants, J., Provinciael, B., Camps, A., Noppen, S., Maes, P., Vermeire, K.
10.1101/2022.02.13.480238 — Posted: 2022-02-14
Next-generation intranasal Covid-19 vaccine: a polymersome-based protein subunit formulation that provides robust protection against multiple variants of concern and early reduction in viral load of the upper airway in the golden Syrian hamster model
Lam, J. H., Shivhare, D., Chia, T. W., Chew, S. L., Sinsinbar, G., Aw, T. Y., Wong, S., Venkataraman, S., Lim, F. W. I., Vandepapeliere, P., Nallani, M.
10.1101/2022.02.12.480188 — Posted: 2022-02-14
Distinct upper airway epithelium interferon-stimulated and profibrotic gene expression between adult and infant rhesus macaques infected with SARS-CoV-2
Langel, S. N., Garrido, C., Phan, C., Travieso, T., DeMarco, T., Ma, Z.-M., Reader, J. R., Olstad, K. J., Sammak, R. L., Shaan Lakshmanappa, Y., Roh, J. W., Watanabe, J., Usachenko, J., Immareddy, R., Pollard, R. E., Iyer, S. S., Permar, S. R., Miller, L., Van Rompay, K. K. A., Blasi, M.
10.1101/2022.02.12.480218 — Posted: 2022-02-14
Molecular dynamics simulations of the Spike trimeric ectodomain of the SARS-CoV-2 Omicron variant: structural relationships with infectivity, evasion to immune system and transmissibility
Amorim, V. M. d. F., de Souza, R. F., Souza, A. S. d., Guzzo, C. R.
10.1101/2022.02.14.480347 — Posted: 2022-02-14
SARS-CoV-2 Omicron triggers cross-reactive neutralization and Fc effector functions in previously vaccinated, but not unvaccinated individuals
Richardson, S. I., Madzorera, V. S., Spencer, H., Manamela, N. P., van der Mescht, M., Lambson, B. E., Oosthuysen, B., Ayres, F., Makhado, Z., Moyo-Gwete, T., Mzindle, N., Motlou, T., Strydom, A., Mendes, A., Tegally, H., de Beer, Z., de Villiers, T. R., Bodenstein, A., van den Berg, G., Venter, M., de Oliviera, T., Ueckermann, V., Rossouw, T. M., Boswell, M. T., Moore, P. L.
10.1101/2022.02.10.22270789 — Posted: 2022-02-14 Discussion: Onsite
Comprehensive humoral and cellular immune responses to SARS-CoV-2 variants in diverse Chinese populations: A benefit perspective of national vaccination
Li, J., Wu, J., Long, Q., Wu, Y., Hu, X., He, Y., Jiang, M., Li, J., Zhao, L., Yang, S., Chen, X., Wang, M., Zheng, J., Wu, F., Wu, R., Ren, L., Bu, L., Wang, H., Li, K., Fu, L., Zhang, G., Zheng, Y., Gao, Z.
10.1101/2022.02.13.22270896 — Posted: 2022-02-14
POST-ACUTE SEQUELAE AND ADAPTIVE IMMUNE RESPONSES IN PEOPLE LIVING WITH HIV RECOVERING FROM SARS-COV-2 INFECTION
Peluso, M. J., Spinelli, M. A., Deveau, T.-M., Forman, C. A., Munter, S. E., Mathur, S., Tang, A. F., Lu, S., Goldberg, S. A., Arreguin, M. I., Hoh, R., Chen, J. Y., Martinez, E. O., Chenna, A., Winslow, J. W., Petropoulos, C. J., Sette, A., Weiskopf, D., Kumar, N., Lynch, K. L., Hunt, P. W., Durstenfeld, M. S., Hsue, P. Y., Kelly, J. D., Martin, J. N., Glidden, D. V., Gandhi, M., Deeks, S. G., Rutishauser, R. L., Henrich, T. J.
10.1101/2022.02.10.22270471 — Posted: 2022-02-14
FOLIC ACID AND METHOTREXATE USE AND THEIR ASSOCIATION WITH COVID-19 DIAGNOSIS AND MORTALITY: AN ANALYSIS FROM THE UK BIOBANK
Topless, R. K., Green, R., Morgan, S. L., Robinson, P. C., Merriman, T. R., Gaffo, A. L.
10.1101/2022.02.10.22270804 — Posted: 2022-02-14
Risk of severe COVID-19 in patients with inflammatory rheumatic diseases treated with immunosuppressive therapy in Scotland
McKeigue, P. M., Porter, D., Hollick, R. J., Ralston, S. J., McAllister, D. A., Colhoun, H. M.
10.1101/2022.02.13.22270898 — Posted: 2022-02-14

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).