COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,440 Articles (22,835 medRxiv, 8,605 bioRxiv)

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Naturally occurring mutations of SARS-CoV-2 main protease confer drug resistance to nirmatrelvir
Hu, Y., Lewandowski, E. M., Tan, H., Morgan, R. T., Zhang, X., Jacobs, L. M., Butler, S. G., Mongora, M. V., Choy, J. S., Chen, Y., Wang, J.
10.1101/2022.06.28.497978 — Posted: 2022-06-28
Peptide from NSP7 is able to form amyloid-like fibrils: artifact or challenge to drug design?
Garmay, Y. P., Rubel, A. A., Egorov, V. V.
10.1101/2022.06.28.497929 — Posted: 2022-06-28
Neutralizing monoclonal antibodies elicited by mosaic RBD nanoparticles bind conserved sarbecovirus epitopes
Fan, C., Cohen, A. A., Park, M., Hung, A. F.-H., Keeffe, J. R., Gnanapragasam, P. N., Lee, Y. E., Kakutani, L. M., Wu, Z., Malecek, K. E., Williams, J. C., Bjorkman, P. J.
10.1101/2022.06.28.497989 — Posted: 2022-06-28
Structural basis of the M-N protein interaction in a SARS-COV-2-related Betacoronavirus
Wang, X., Yang, Y., Sun, Z., Zhou, X.
10.1101/2022.06.28.497981 — Posted: 2022-06-28
Increasing SARS-CoV2 cases, hospitalizations and deaths among the vaccinated elderly populations during the Omicron (B.1.1.529) variant surge in UK.
Emani, V. R. R., Pallipuram, V. K., Goswami, K. K., Maddula, K. R., Reddy, R., Nakka, A. S., Panga, S., Reddy, N. K., Reddy, N. K., Nandanoor, D., Goswami, S.
10.1101/2022.06.28.22276926 — Posted: 2022-06-28
The Staphylococcus aureus iron-regulated surface determinant A (IsdA) increases SARS CoV-2 replication by modulating JAK-STAT signaling
Goncheva, M. I., Gibson, R., Shouldice, A. C., Dikeakos, J. D., Heinrichs, D. E.
10.1101/2022.06.27.497883 — Posted: 2022-06-28
Combination therapy with nirmatrelvir and molnupiravir improves the survival of SARS-CoV-2 infected mice
Jeong, J. H., Chokkakula, S., Min, S. C., Kim, B., Choi, W.-S., Oh, S., Yun, Y. S., Kang, D. H., Lee, O.-J., Kim, E.-G., Choi, J.-H., Lee, J.-Y., Choi, Y. K., Baek, Y. H., Song, M.-S.
10.1101/2022.06.27.497875 — Posted: 2022-06-28
Pre-existing immunity modulates responses to mRNA boosters
Dangi, T., Sanchez, S., Lew, M. H., Visvabharathy, L., Richner, J. M., Koralnik, I., Penaloza-MacMaster, P.
10.1101/2022.06.27.497248 — Posted: 2022-06-28
Structure-based inhibitor optimization for the Nsp3 Macrodomain of SARS-CoV-2
Gahbauer, S., Correy, G. J., Schuller, M., Ferla, M. P., Doruk, Y. U., Rachman, M., Wu, T., Diolaiti, M., Wang, S., Neitz, J., Fearon, D., Radchenko, D. S., Moroz, Y., Irwin, J. J., Renslo, A. R., Taylor, J. C., Gestwicki, J. E., von Delft, F., Ashworth, A., Ahel, I., Shoichet, B. K., Fraser, J. S.
10.1101/2022.06.27.497816 — Posted: 2022-06-28
Outcomes of laboratory-confirmed SARS-CoV-2 infection during resurgence driven by Omicron lineages BA.4 and BA.5 compared with previous waves in the Western Cape Province, South Africa
Davies, M.-A., Morden, E., Rosseau, P., Arendse, J., Bam, J.-L., Boloko, L., Cloete, K., Cohen, C., Chetty, N., Dane, P., Heekes, A., Hsiao, N.-Y., Hunter, M., Hussey, H., Jacobs, T., Jassat, W., Kariem, S., Kassanjee, R., Laenen, I., Le Roux, S., Lessells, R., Mahomed, H., Maughan, D., Meintjes, G., Mendelson, M., Mnguni, A., Moodley, M., Murie, K., Naude, J., Ntusi, N. A. B., Paleker, M., Parker, A., Pienaar, D., Preiser, W., Prozesky, H., Raubenheimer, P., Rossouw, L., Schreuder, N., Smith, B., Smith, M., Solomon, W., Symons, G., Taljaard, J., Wasserman, S., Wilkisnon, R., Wolmarans, M., Wolter, N., Boulle, A., Western Cape Department of Health and Wellness, , National Departments of Health, , National Institute for Communicable Diseases in South Africa
10.1101/2022.06.28.22276983 — Posted: 2022-06-28

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