COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,031 Articles (22,627 medRxiv, 8,404 bioRxiv)

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Do Existing COVID-19 Vaccines Need to Be Updated in 2025?
Mellis, I. A., Wu, M., Wang, Q., Bowen, A., Gherasim, C., Pierce, V. M., Shah, J. G., Purpura, L. J., Yin, M. T., Gordon, A., Guo, Y., Ho, D. D.
10.1101/2025.05.02.651777 — Posted: 2025-05-05
Morbidity, Mortality and Immunization in Severe COVID-19 Among the Elderly in Brazil: A Five-Year Perspective
Candido-Sobrinho, S. A., Souza Junior, F. d., Silva-Filho, J. Q. d., Viana, V. A. F., Moreira Lima, A. A.
10.1101/2025.05.01.25326813 — Posted: 2025-05-03
COVID-19 mortality and government response in the Philippines
Migrino, J. R., Martinez, L. R. S.
10.1101/2025.04.30.25326774 — Posted: 2025-05-02
Institutional Characteristics Associated with Accessing and Sharing EHR Data with the National COVID Cohort Collaborative (N3C)
Rose, C. M., Bush, W. S., Beno, M. F., Williams, S. M., Haines, J. L., Crawford, D. C.
10.1101/2025.05.01.25326202 — Posted: 2025-05-02
A randomised-controlled Phase I de-escalation trial of Molnupiravir and Nirmatrelvir/Ritonavir combination for mild-moderate SARS-CoV-2 infection
Khoo, S. H., FitzGerald, R., Edwards, C. J., Ahmad, S., Saunders, G., Else, L. J., Shaw, V., Mozgunov, P., Northey, J., Dickinson, L., Knox, E., Buadi, A., Hale, C., Reynolds, H. E., Middleton, C., Bullock, K., Walker, L., Tetlow, M., Lyon, R., Gibney, J., Amara, A., Greenhalf, W., Burdon, A., Dixon, J., Jaki, T., Chiong, J., Lalloo, D. G., Owen, A., Jacobs, M., Fletcher, T., Griffiths, G.
10.1101/2025.05.01.25326797 — Posted: 2025-05-02
Deep vein thrombosis in critically ill patients with COVID-19: incidence, Wells score diagnosis validation, and hospital prognosis
da Fonseca, C. C., Perazzo, H., Wagner, S., Tavares, I. C. F., Diniz, M. P., Moreira, R. d. C., Coelho, L. E., Jalil, E., Japiassu, A. M., Gouvea, E. P., Nunes, E. P., Boechat, H., Gouvea, L. B., Ferreira, M. T., Azambuja-Rodrigues, P. M., Moreira, R. I., Geraldo, K. M., Freitas, L. A. d., Pacheco, V. V., Grinsztein, B. G. J., Brasil, P. E. A. A. d.
10.1101/2025.04.30.25326684 — Posted: 2025-05-02
Can the Chest X-ray Brixia Score predict COVID-19 disease severity and mortality in resource-limited settings? A retrospective cross-sectional study at a tertiary hospital in Northwestern, Tanzania
Mbwilo, D., Byekwaso, Z., Elisenguo, E., Hyera, F., Msaki, E., Akrabi, A. M., Seni, J., Wajanga, B., Ngoya, P. S.
10.1101/2025.05.01.25326785 — Posted: 2025-05-02
Dissecting serum polyclonal antibody escape to SARS-CoV-2 variants by deep mutational learning
Shlesinger, D., Sadilek, V., Minot, M., Stamkopoulos, E., Bikias, T., Kuhn, R., Agrafiotis, A., Taft, J. M., Yermanos, A., Reddy, S. T.
10.1101/2025.05.01.651552 — Posted: 2025-05-02
Modeling epithelial and endothelial cell tropism for SARS-CoV-2 through restricted transgenic hACE2 expression in mice
Lameire, S., Debeuf, N., Deckers, J., De Wolf, C., Vanheerswynghels, M., Toussaint, W., De Vlieger, L., Van Hoecke, L., De Cae, S., Schepens, B., Vanhee, S., Lambrecht, B. N.
10.1101/2025.05.01.651662 — Posted: 2025-05-02
Expression and Characterization of SARS-CoV-2 Spike Protein in Thermothelomyces heterothallica C1
Ophir, Y., Wong, J., Haddad, K. R., Huuskonen, A., Karmaker, A., Gore, V., Jung, S., Oloumi, A., Liu, Y., Fu, J., Zhang, L., Huang, P., Minami, S. A., Garimella, S. S., Thyagatur, A., Zaini, P. A., Vitikainen, M., Tchelet, R., Valbuena, N., Fuerst, T., Korkmaz, E., Falo, L. D., Balmert, S. C., Mahendiratta, S., Emalfarb, M., Shah, P., Siegel, J. B., Dandekar, A. M., Chen, X., Lebrilla, C. B., Faller, R., Saloheimo, M., McDonald, K. A., Nandi, S.
10.1101/2025.05.01.651343 — Posted: 2025-05-02

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).