COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,959 Articles (22,604 medRxiv, 8,355 bioRxiv)

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The Role of SARS-CoV-2 Nucleocapsid Protein Persistence in Inducing Chronic Type I Interferon and Mitochondrial Dysfunction.
Koenig, A., Quasem, M., Zink, B., Abdulla-Zoda, D., Karunanidhi, P., Sienko, K., Geier, C., Jayaraman, V., Malik, R., Ahmed, K., Shanley, P. F., Koenig, I. A.
10.1101/2025.06.02.657400 — Posted: 2025-06-03
Impact of first SARS-CoV-2 infection variant on serological responses against Omicron: findings from the SIREN study
Insalata, F., Atti, A., Carr, E. J., Otter, A. D., SIREN study group, , Foulkes, S., Dowgier, G., Hobbs, A., Wu, M. Y., Hopkins, S., Charlett, A., Beale, R., Hall, V. J.
10.1101/2025.06.02.25328497 — Posted: 2025-06-02
Diverse tendencies in codon usage evolution of SARS-CoV-2 genes
Blazej, P., Mackiewicz, D., Mackiewicz, P.
10.1101/2025.05.30.657095 — Posted: 2025-06-02
Long-term risk of post-acute sequelae among adults following SARS-CoV-2 or influenza virus infection: a retrospective cohort study in a large, integrated healthcare system
Lewnard, J. A., Malden, D. E., Hong, V., Skela, J., Feldstein, L. R., Saydah, S., Reyes, I. A. C., Hechter, R. C., Sy, L. S., Ackerson, B. K., Tartof, S. Y.
10.1101/2025.05.30.25328674 — Posted: 2025-06-01
Risk of Post-COVID Conditions among adolescents and adults who received nirmatrelvir-ritonavir for acute COVID-19: a retrospective cohort study
Dalton, A. F., Baca, S., Raykin, J., Gregory, C. O., Boehmer, T. K., Koumans, E. H., Patel, P., Patel, P., Saydeh, S.
10.1101/2025.05.30.25327809 — Posted: 2025-05-31
Seasonal Trends of COVID-19 Deaths in Italy: A Confirmatory Linear Regression Study with Time Series Data from 2024/2025
Roccetti, M.
10.1101/2025.05.30.25328619 — Posted: 2025-05-31
De novo design of hundreds of functional GPCR-targeting antibodies enabled by scaling test-time compute
Nabla Bio, , Biswas, S.
10.1101/2025.05.28.656709 — Posted: 2025-05-30
IL-32 drives inflammatory responses in IFN-γ primed human macrophages via a Myddosome-dependent pathway and is elevated in COVID-19
Ramon Vazquez, A., Skowyra, A., Crowley, T., Velmurugan, J., Lee, C., Lindsay, A. J., Woznicki, J. A., Stamou, P., Nelson, O., Jeffery, I. B., Lohan, A. J., Albrich, W. C., O Mahony, L., Melgar, S., Shanahan, F., Cao, X., Macoritto, M., Sadhukhan, R., Levesque, M. C., McRae, B. L., Matzelle, M., Nally, K.
10.1101/2025.05.29.656795 — Posted: 2025-05-30
A Plasma Membrane Vesicle Imaging-Based Platform for Studying Membrane Fusion
Yosibash, I., Khan, S., Lichtenstein, A., Dharan, R., Vaknin, A., Daniel, S., Avinoam, O., Sorkin, R.
10.1101/2025.05.29.656808 — Posted: 2025-05-30
A non-spike nucleocapsid R204P mutation in SARS-CoV-2 Omicron XEC enhances inflammation and pathogenicity
Tsujino, S., Tsuda, M., Ito, J., Deguchi, S., Taha, T. Y., Nasser, H., Wang, L., Rosecrans, J., Suzuki, R., Suzuki, S., Yoshimatsu, K., Ott, M., The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Ikeda, T., Takayama, K., Sato, K., Tanaka, S., Tamura, T., Fukuhara, T.
10.1101/2025.05.28.656516 — Posted: 2025-05-30

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).