COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,629 Articles (22,913 medRxiv, 8,716 bioRxiv)

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Binding and Neutralizing Antibody Responses to SARS-CoV-2 in Infants and Young Children Exceed Those in Adults
Karron, R. A., Quesada, M. G., Schappell, E. A., Schmidt, S. D., Knoll, M. D., Hetrich, M. K., Veguilla, V., Doria-Rose, N., Dawood, F. S., SEARCh Study Team
10.1101/2021.12.20.21268034 — Posted: 2021-12-21
SARS-CoV-2 spike conformation determines plasma neutralizing activity
Bowen, J. E., Walls, A. C., Joshi, A., Sprouse, K. R., Stewart, C., Tortorici, M. A., Franko, N. M., Logue, J. K., Mazzitelli, I. G., Tiles, S. W., Ahmed, K., Shariq, A., Snell, G., Iqbal, N. T., Geffner, J., Bandera, A., Gori, A., Grifantini, R., Chu, H. Y., Van Voorhis, W. C., Corti, D., Veesler, D.
10.1101/2021.12.19.473391 — Posted: 2021-12-21
Arsenal of Nanobodies for Broad-Spectrum Countermeasures against Current and Future SARS-CoV-2 Variants of Concerns
Rossotti, M. A., van Faassen, H., Tran, A., Sheff, J., Sandhu, J. A., Duque, D., Hewitt, M., Wen, S., Bavananthasivam, R., Beitari, S., Matte, K., Laroche, G., Giguere, P. M., Gervais, C., Stuible, M., Guimond, J., Perret, S., Hussack, G., Langlois, M.-A., Durocher, Y., Tanha, J.
10.1101/2021.12.20.473401 — Posted: 2021-12-21
The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors
Ma, Y., Yang, K., Geng, Z. Z., Alugubellia, Y. R., Shaabani, N., Vatansever, E. C., Ma, X. R., Cho, C.-C., Khatua, K., Blankenship, L., Yu, G., Sankaran, B., Li, P., Allen, R., Ji, H., Xu, S., Liu, W. R.
10.1101/2021.12.18.473326 — Posted: 2021-12-21
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion
Mannar, D., Saville, J. W., Zhu, X., Srivastava, S. S., Berezuk, A. M., Tuttle, K., Marquez, C., Sekirov, I., Subramaniam, S.
10.1101/2021.12.19.473380 — Posted: 2021-12-21
Human genetic variants associated with COVID-19 severity are enriched in immune and epithelium regulatory networks
Feng, Z., Ren, X., Duren, Z., Wang, Y.
10.1101/2021.12.17.473140 — Posted: 2021-12-21
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
Meng, B., Ferreira, I., Abdullahi, A., Kemp, S. A., Goonawardane, N., Papa, G., Fatihi, S., Charles, O., Collier, D., CITIID-NIHR BioResource COVID-19 Collaboration, , The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Choi, J., Hyeon Lee, J., Mlcochova, P., James, L., Doffinger, R., Thukral, L., Sato, K., Gupta, R. K.
10.1101/2021.12.17.473248 — Posted: 2021-12-21
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors
Chen, K.-Y., Krischuns, T., Ortega Varga, L., Harigua-Souiai, E., Paisant, S., Zettor, A., Chiaravalli, J., Courtney, D., O'Brien, A., Baker, S., Isel, C., Agou, F., Jacob, Y., Blondel, A., Naffakh, N.
10.1101/2021.12.18.473303 — Posted: 2021-12-21
APOBEC-mediated Editing of SARS-CoV-2 Genomic RNA Impacts Viral Replication and Fitness
Chen, X., Kim, K., Calabrese, P., Wang, S., Qin, C., Rao, Y., Feng, P.
10.1101/2021.12.18.473309 — Posted: 2021-12-21
ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
Ching, K. L., de Vries, M., Gago, J., Dancel-Manning, K., Sall, J., Rice, W. J., Barnett, C., Liang, F.-X., Thorpe, L. E., Shopsin, B., Segal, L. N., Dittmann, M., Torres, V. J., Cadwell, K.
10.1101/2021.12.17.473223 — Posted: 2021-12-20

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