COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,302 Articles (22,772 medRxiv, 8,530 bioRxiv)

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Passage of SARS-CoV-2 in cells expressing human and mouse ACE2 selects for mouse-adapted and ACE2-independent viruses
Yan, K., Dumenil, T., Le, T. T., Tang, B., Bishop, C., Suhrbier, A., Rawle, D. J.
10.1101/2021.12.16.473063 — Posted: 2021-12-21
Context-specific emergence and growth of the SARS-CoV-2 Delta variant
McCrone, J. T., Hill, V., Bajaj, S., Evans Pena, R., Lambert, B. C., Inward, R., Bhatt, S., Volz, E., Ruis, C., Dellicour, S., Baele, G., Zarebski, A. E., Sadilek, A., Wu, N., Schneider, A., Ji, X., Raghwani, J., Jackson, B., Colquhoun, R., O'Toole, A., Peacock, T. P., Twohig, K., Thelwall, S., Dabrera, G., Myers, R., The COVID-19 genomics UK (COG-UK) consortium, , Faria, N. R., Huber, C., Bogoch, I. I., Khan, K., Plessis, L. d., Barrett, J. C., Aanensen, D. M., Barclay, W. S., Chand, M., Connor, T., Loman, N. J., Suchard, M. A., Pybus, O. G., Rambaut, A., Kraemer, M. U. G.
10.1101/2021.12.14.21267606 — Posted: 2021-12-21
Randomized Controlled Trial of Early Outpatient COVID-19 Treatment with High-Titer Convalescent Plasma
Sullivan, D. J., Gebo, K. A., Shoham, S., Bloch, E. M., Lau, B., Shenoy, A. G., Mosnaim, G. S., Gniadek, T. J., Fukuta, Y., Patel, B., Heath, S. L., Levine, A. C., Meisenberg, B. R., Spivak, E. S., Anjan, S., Huaman, M. A., Blair, J. E., Currier, J. S., Paxton, J. H., Gerber, J. M., Petrini, J. R., Broderick, P. B., Rausch, W., Cordisco, M. E., Hammel, J., Greenblatt, B., Cluzet, V. C., Cruser, D., Oei, K., Abinante, M., Hammit, L. L., Suttcliffe, C. G., Forthal, D. N., Zand, M. S., Cachay, E. R., Raval, J. S., Kassaye, S. G., Foster, C., Roth, M., Marshall, C. E., Yarava, A., Lane, K., McBee, N. A., Gawad, A. L., Karlen, N., Singh, A., Ford, D. E., Jabs, D. A., Appel, L. J., Shade, D. M., Ehrhardt, S., Baksh, S. N., Laeyendecker, O., Pekosz, A., Klein, S., Casadevall, A., Tobian, A. A., Hanley, D. F.
10.1101/2021.12.10.21267485 — Posted: 2021-12-21
Binding and Neutralizing Antibody Responses to SARS-CoV-2 in Infants and Young Children Exceed Those in Adults
Karron, R. A., Quesada, M. G., Schappell, E. A., Schmidt, S. D., Knoll, M. D., Hetrich, M. K., Veguilla, V., Doria-Rose, N., Dawood, F. S., SEARCh Study Team
10.1101/2021.12.20.21268034 — Posted: 2021-12-21
SARS-CoV-2 spike conformation determines plasma neutralizing activity
Bowen, J. E., Walls, A. C., Joshi, A., Sprouse, K. R., Stewart, C., Tortorici, M. A., Franko, N. M., Logue, J. K., Mazzitelli, I. G., Tiles, S. W., Ahmed, K., Shariq, A., Snell, G., Iqbal, N. T., Geffner, J., Bandera, A., Gori, A., Grifantini, R., Chu, H. Y., Van Voorhis, W. C., Corti, D., Veesler, D.
10.1101/2021.12.19.473391 — Posted: 2021-12-21
Arsenal of Nanobodies for Broad-Spectrum Countermeasures against Current and Future SARS-CoV-2 Variants of Concerns
Rossotti, M. A., van Faassen, H., Tran, A., Sheff, J., Sandhu, J. A., Duque, D., Hewitt, M., Wen, S., Bavananthasivam, R., Beitari, S., Matte, K., Laroche, G., Giguere, P. M., Gervais, C., Stuible, M., Guimond, J., Perret, S., Hussack, G., Langlois, M.-A., Durocher, Y., Tanha, J.
10.1101/2021.12.20.473401 — Posted: 2021-12-21
The P3 O-Tert-Butyl-Threonine is Key to High Cellular and Antiviral Potency for Aldehyde-Based SARS-CoV-2 Main Protease Inhibitors
Ma, Y., Yang, K., Geng, Z. Z., Alugubellia, Y. R., Shaabani, N., Vatansever, E. C., Ma, X. R., Cho, C.-C., Khatua, K., Blankenship, L., Yu, G., Sankaran, B., Li, P., Allen, R., Ji, H., Xu, S., Liu, W. R.
10.1101/2021.12.18.473326 — Posted: 2021-12-21
SARS-CoV-2 Omicron Variant: ACE2 Binding, Cryo-EM Structure of Spike Protein-ACE2 Complex and Antibody Evasion
Mannar, D., Saville, J. W., Zhu, X., Srivastava, S. S., Berezuk, A. M., Tuttle, K., Marquez, C., Sekirov, I., Subramaniam, S.
10.1101/2021.12.19.473380 — Posted: 2021-12-21
Human genetic variants associated with COVID-19 severity are enriched in immune and epithelium regulatory networks
Feng, Z., Ren, X., Duren, Z., Wang, Y.
10.1101/2021.12.17.473140 — Posted: 2021-12-21
SARS-CoV-2 Omicron spike mediated immune escape, infectivity and cell-cell fusion
Meng, B., Ferreira, I., Abdullahi, A., Kemp, S. A., Goonawardane, N., Papa, G., Fatihi, S., Charles, O., Collier, D., CITIID-NIHR BioResource COVID-19 Collaboration, , The Genotype to Phenotype Japan (G2P-Japan) Consortium, , Choi, J., Hyeon Lee, J., Mlcochova, P., James, L., Doffinger, R., Thukral, L., Sato, K., Gupta, R. K.
10.1101/2021.12.17.473248 — Posted: 2021-12-21

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).