COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,784 Articles (22,523 medRxiv, 8,261 bioRxiv)

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Immune escape of SARS-CoV-2 Omicron variant from mRNA vaccination-elicited RBD-specific memory B cells.
Sokal, A., Broketa, M., Meola, A., Barba-Spaeth, G., Fernandez, I., Fourati, S., Azzaoui, I., de La Selle, A., Vandenberghe, A., Roeser, A., Bouvier-Alias, M., Crickx, E., Languille, L., Michel, M., Godeau, B., Gallien, S., Melica, G., Nguyen, Y., Zarrouk, V., Canoui-Poitrine, F., Noizat-Pirenne, F., Megret, J., Pawlotsky, J.-M., Fillatreau, S., Simon-Loriere, E., Weill, J.-C., Reynaud, C.-A., Rey, F. A., Bruhns, P., Chappert, P., Mahevas, M.
10.1101/2021.12.21.473528 — Posted: 2021-12-22
mRNA-1273 and BNT162b2 mRNA vaccines have reduced neutralizing activity against the SARS-CoV-2 Omicron variant
Edara, V.-V., Manning, K. E., Ellis, M., Lai, L., Moore, K. M., Foster, S. L., Floyd, K., Davis-Gardner, M. E., Mantus, G., Nyhoff, L. E., Bechnack, S., Alaaeddine, G., Naji, A., Samaha, H., Lee, M., Bristow, L., Hussaini, L., Ciric, C. R., Nguyen, P.-V., Gagne, M., Roberts-Torres, J., Henry, A. R., Godbole, S., Grakoui, A., Sexton, M., Piantadosi, A., Waggoner, J. J., Douek, D. C., Anderson, E. J., Rouphael, N., Wrammert, J., Suthar, M. S.
10.1101/2021.12.20.473557 — Posted: 2021-12-22
Longitudinal characterisation of phagocytic and neutralisation functions of anti-Spike antibodies in plasma of patients after SARS-CoV-2 infection.
Adhikari, A., Abayasingam, A., Rodrigo, C., Agapiou, D., Pandzic, E., Brasher, N. A., Fernando, B. S. M., Keoshkerian, E., Li, H., Kim, H. N., Lord, M., Popovic, G., Rawlinson, W., Mina, M., Post, J. J., Hudson, B., Gilroy, N., Bartlett, A. W., Ahlenstiel, G., Grubor-Bauk, B., Dwyer, D., Konecny, P., Lloyd, A. R., Martinello, M., Bull, R. A., Tedla, N.
10.1101/2021.12.21.473774 — Posted: 2021-12-22
Engineered High-Affinity ACE2 Peptide Mitigates ARDS and Death Induced by Multiple SARS-CoV-2 Variants
Zhang, L., Dutta, S., Xiong, S., Chan, M., Chan, K. K., Fan, T. M., Bailey, K. L., Lindeblad, M., Cooper, L. M., Rong, L., Gugliuzza, A. F., Shukla, D., Procko, E., Rehman, J., Malik, A. B.
10.1101/2021.12.21.473668 — Posted: 2021-12-22
An in silico analysis of early SARS-CoV-2 variant B.1.1.529 (Omicron) genomic sequences and their epidemiological correlates
Kumar, A., Asghar, A., Singh, H. N., Faiq, M. A., Kumar, S., Narayan, R. K., Kumar, G., Dwivedi, P., Sahni, C., Jha, R. K., Kulandhasamy, M., Prasoon, P., Sesham, K., Kant, K., Pandey, S. N.
10.1101/2021.12.18.21267908 — Posted: 2021-12-22
Analytical sensitivity of seven SARS-CoV-2 antigen-detecting rapid tests for Omicron variant
Bekliz, M., Adea, K., Alvarez, C., Essaidi-Laziosi, M., Escadafal, C., Kaiser, L., Eckerle, I.
10.1101/2021.12.18.21268018 — Posted: 2021-12-22 Discussion: Onsite | Offsite
Structural flexibility of the SARS-CoV-2 genome relevant to variation, replication, pathogenicity, and immune evasion.
Patarca, R., Haseltine, W. A.
10.1101/2021.12.20.473542 — Posted: 2021-12-21
Vaccine effectiveness against SARS-CoV-2 infection with the Omicron or Delta variants following a two-dose or booster BNT162b2 or mRNA-1273 vaccination series: A Danish cohort study
Hansen, C. H., Schelde, A. B., Moustsen-Helms, I. R., Emborg, H.-D., Krause, T. G., Moelbak, K., Valentiner-Branth, P., The Infectious Disease Preparedness Group at Statens Serum Institut
10.1101/2021.12.20.21267966 — Posted: 2021-12-21 Discussion: Onsite
Rapid epidemic expansion of the SARS-CoV-2 Omicron variant in southern Africa
Viana, R., Moyo, S., Amoako, D. G., Tegally, H., Scheepers, C., Lessells, R. J., Giandhari, J., Wolter, N., Everatt, J., Rambaut, A., Althaus, C., Wilkinson, E., Mendes, A., Strydom, A., Davids, M., Mayaphi, S., Gaseitsiwe, S., Choga, W. T., Maruapula, D., Zuze, B., Radibe, B., Koopile, L., Shapiro, R., Lockman, S., Mbulawa, M. B., Mphoyakgosi, T., Smith-Lawrence, P., Mosepele, M., Matshaba, M., Masupu, K., Chand, M., Joseph, C., Kuate-Lere, L., Lesetedi-Mafoko, O., Moruisi, K., Scott, L., Stevens, W., Wibmer, C. K., Mnguni, A., Ismail, A., Mahlangu, B., Martin, D. P., Hill, V., Colquhoun, R.
10.1101/2021.12.19.21268028 — Posted: 2021-12-21
GB0139, an inhaled small molecule inhibitor of galectin-3, in COVID-19 pneumonitis: a randomised, controlled, open-label, phase 2a experimental medicine trial of the safety, pharmacokinetics, and potential therapeutic value
Gaughan, E., Sethi, T., Quinn, T., Hirani, N., Mills, A., Bruce, A. M., MacKinnon, A., Aslanis, V., Li, F., O'Connor, R., Parker, R. A., Norrie, J., Dear, J., Akram, A. R., Koch, O., Wang-Jairaj, J., Slack, R. J., Gravelle, L., Lindmark, B., Dhaliwal, K.
10.1101/2021.12.21.21267983 — Posted: 2021-12-21

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).