COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,755 Articles (22,502 medRxiv, 8,253 bioRxiv)

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Structural and Computational Design of a SARS-CoV-2 Spike Antigen with Increased Receptor Binding Domain Exposure and Improved Immunogenicity
Williams, J., Biancucci, M., Lessen, L., Tian, S., Balsaraf, A., Chen, L., Chesterman, C., Maruggi, G., Vandepaer, S., Huang, Y., Mallett, C., Steff, A.-M., Bottomley, M., Malito, E., Wahome, N., Harshbarger, W.
10.1101/2022.11.29.518231 — Posted: 2022-11-29
Evolving SARS-CoV-2 virulence among hospital and university affiliates in Spain and Greater Boston
Amer, F., Lan, F.-Y., Gil-Conesa, M., Sidossis, A., Bruque, D., Iliaki, E., Buley, J., Nathan, N., Bruno-Murtha, L. A., Carlos-Chilleron, S., Kales, S. N., Fernandez-Montero, A.
10.1101/2022.11.28.22282412 — Posted: 2022-11-29
Characteristics and outcomes of patients with COVID-19 at high-risk of disease progression receiving sotrovimab, oral antivirals or no treatment in England
Patel, V., Yarwood, M. J., Levick, B., Gibbons, D. C., Drysdale, M., Kerr, W., Watkins, J. D., Young, S., Pierce, B. F., Lloyd, E. J., Birch, H. J., Kamalati, T., Brett, S. J.
10.1101/2022.11.28.22282808 — Posted: 2022-11-29
Comparative effectiveness of heterologous booster schedules with AZD1222, BNT162b2, or mRNA-1273 vaccines against COVID-19 during omicron predominance in the Nordic countries
Andersson, N. W., Thiesson, E. M., Baum, U., Pihlstrom, N., Starrfelt, J., Faksova, K., Poukka, E., Lund, L. C., Hansen, C. H., Aakjaer, M., Andersen, M., Kjaer, J., Cohet, C., Goossens, M., Hallas, J., Meijerink, H., Rickard, L., Hviid, A.
10.1101/2022.11.24.22282651 — Posted: 2022-11-29
Fc-gamma receptor-dependent antibody effector functions are required for vaccine protection against infection by antigenic variants of SARS-CoV-2
Mackin, S. R., Desai, P., Whitener, B. M., Karl, C. E., Liu, M., Baric, R. S., Edwards, D. K., Chicz, T. M., McNamara, R. P., Alter, G., Diamond, M. S.
10.1101/2022.11.27.518117 — Posted: 2022-11-29
Fc mediated pan-sarbecovirus protection after alphavirus vector vaccination
Adams, L. E., Leist, S. R., Dinnon, K. H., West, A., Gully, K. L., Anderson, E., Loome, J. F., Madden, E., Powers, J., Schaefer, A., Sarkar, S., Castillo, I., Maron, J., McNamara, R. P., Bertera, H. L., Zweigart, M. R., Higgins, J. S., Hampton, B. K., Lakshmanane, P., Alter, G., Montgomery, S., Baxter, V., Heise, M. T., Baric, R. S.
10.1101/2022.11.28.518175 — Posted: 2022-11-28
Extracellular disintegration of viral proteins as an innovative strategy for developing broad-spectrum antivirals against coronavirus
Sun, K., Ding, Z., Jia, X., Cheng, H., Li, Y., Wu, Y., Li, Z., Huang, X., Pu, F., Li, E., Wang, G., Wang, W., Ding, Y., Wong, G., Chiu, S., Lan, J., Hu, A.
10.1101/2022.11.24.517008 — Posted: 2022-11-28
SARS-CoV-2 Spike Protein Induces Hemagglutination: Implications for COVID-19 Morbidities and Therapeutics and for Vaccine Adverse Effects
Boschi, C., Scheim, D. E., Bancod, A., Millitello, M., Le Bideau, M., Colson, P., Fantini, J., La Scola, B.
10.1101/2022.11.24.517882 — Posted: 2022-11-28
Highly potent antisense oligonucleotides (ASOs) targeting the SARS-CoV-2 RNA genome
Dauksaite, V., Tas, A., Wachowius, F., Spruit, A., van Hemert, M., Snijder, E., van der Veer, E. P., van Zonneveld, A. J.
10.1101/2022.11.28.518195 — Posted: 2022-11-28
Alarming antibody evasion properties of rising SARS-CoV-2 BQ and XBB subvariants
Wang, Q., Iketani, S., Li, Z., Liu, L., Guo, Y., Huang, Y., Bowen, A. D., Liu, M., Wang, M., Yu, J., Valdez, R., Lauring, A. S., Sheng, Z., Wang, H. H., Gordon, A., Liu, L., Ho, D. D.
10.1101/2022.11.23.517532 — Posted: 2022-11-28

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).