COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,629 Articles (22,913 medRxiv, 8,716 bioRxiv)

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Discovery of Potent Pyrazoline-Based Covalent SARS-CoV-2 Main Protease Inhibitors
Moon, P., Boike, L., Dovala, D., Henning, N. J., Knapp, M., Spradlin, J. N., Ward, C. C., Wolleb, H., Zammit, C. M., Fuller, D., Blake, G., Murphy, J. P., Wang, F., Lu, Y., Moquin, S. A., Tandeske, L., Hesse, M. J., McKenna, J. M., Tallarico, J., Schirle, M., Toste, F. D., Nomura, D. K.
10.1101/2022.03.05.483025 — Posted: 2022-03-07
Low expression of EXOSC2 protects against clinical COVID-19 and impedes SARS-CoV-2 replication
Moll, T., Odon, V., Harvey, C., Collins, M., Peden, A., Franklin, J., Graves, E., Marshall, J., dos Santos Souza, C., Zhang, S., Azzouz, M., Gordon, D., Krogan, N., Ferraiuolo, L., Snyder, M., Shaw, P., Rehwinkel, J., Cooper-Knock, J.
10.1101/2022.03.06.483172 — Posted: 2022-03-07
Crippled Coronavirus: 5'-PolyU targeted Oligo prevents development of infectious Virions
Ullah, H., Averick, S., Tang, Q.
10.1101/2022.03.04.483076 — Posted: 2022-03-07
Chimeric mRNA based COVID-19 vaccine elicits potent neutralizing antibodies and protection against Omicron and Delta
Hu, Q., Zhao, Y., Shaabani, N., Lyu, X., Sun, H., Cruz, V., Kao, Y., Xu, J., Fossier, A., Stegman, K., Wang, Z., Wang, Z., Hu, Y., Zheng, Y., Kyaw, L., Zuluaga, C., Wang, H., Pei, H., Powers, C., Allen, R., Xie, H., Ji, H., Chen, R.
10.1101/2022.03.04.483032 — Posted: 2022-03-07
Soluble P2X7 receptor is elevated in the plasma of COVID-19 patients and correlates with disease severity
Garcia-Villalba, J., Hurtado-Navarro, L., Penin-Franch, A., Molina-Lopez, C., Martinez-Alarcon, L., Angosto-Bazarra, D., Baroja-Mazo, A., Pelegrin, P.
10.1101/2022.03.04.483019 — Posted: 2022-03-07
Characterization of Hydrophobic Interactions of SARS-CoV-2 and MERS-CoV Spike Protein Fusion Peptides Using Single Molecule Force Measurements
Qiu, C., Whittaker, G., Gellman, S. H., Daniel, S., Abbott, N. L.
10.1101/2022.03.05.483104 — Posted: 2022-03-07
Different forms of superspreading lead to different outcomes: heterogeneity in infectiousness and contact behavior relevant for the case of SARS-CoV-2
Kuylen, E. J., Torneri, A., Willem, L., Libin, P. J. K., Abrams, S., Coletti, P., Franco, N., Verelst, F., Beutels, P., Liesenborgs, J., Hens, N.
10.1101/2022.03.03.22271824 — Posted: 2022-03-06
COVID-19 Hospitalisation in Portugal, the first year: Results from hospital discharge data
Pereira, J. P., Caetano, C., Antunes, L., Patricio, P., Morgado, M. L., Nunes, B.
10.1101/2022.03.03.22271349 — Posted: 2022-03-06
Immunogenicity and Safety of Booster Dose of S-268019-b or Tozinameran in Japanese Participants: An Interim Report of Phase 2/3, Randomized, Observer-Blinded, Noninferiority Study
Shinkai, M., Sonoyama, T., Kamitani, A., Shibata, R., Seki, N., Omoto, S., Shinoda, M., Sato, T., Ishii, N., Igarashi, K., Ariyasu, M.
10.1101/2022.03.03.22271827 — Posted: 2022-03-06
Open label phase I/II clinical trial and predicted efficacy of SARS-CoV-2 RBD protein vaccines SOBERANA 02 and SOBERANA Plus in children
Puga Gomez, R., Ricardo Delgado, Y., Rojas Iriarte, C., Cespedes Henriquez, L., Bello, M. P., Bello, M. P., Vega Mendoza, D. L., Pestana Perez, N., Paredes-Moreno, B., Rodriguez Gonzalez, M., Valenzuela-Silva, C., Sanchez-Ramirez, B., Rodriguez-Noda, L., Perez Nicado, R., Gonzalez-Mugica, R., Hernandez-Garcia, T., Fundora-Barrios, T., Dubet Echevarria, M., Enriquez-Puertas, J. M., Infante Hernandez, Y., Palenzuela-Diaz, A., Gato Orozco, E., Chappi-Estevez, Y., Francisco-Perez, J. C., Suarez Martinez, M., Castillo-Quintana, I. C., Fernandez-Castillo, S., Climent-Ruiz, Y., Santana-Mederos, D., Garcia-Vega, Y., Toledo-Romani, M. E., Valdes-Balbin, Y., Garcia Rivera, D., Verez-Bencomo, v., SOBERANA Research Group.
10.1101/2022.03.03.22271313 — Posted: 2022-03-06

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).