COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,503 Articles (22,866 medRxiv, 8,637 bioRxiv)

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Repeated SARS-CoV-2 Antigenic Exposures from Prior Vaccinations and Infections Demonstrate Limits of Antibody Durability and Breadth Against Newer Variants
WANG, W., Goguet, e., Lusvarghi, S., Paz, S., Shrestha, L., Vassell, R., Pollett, S., Mitre, E., Weiss, C. D.
10.64898/2026.04.15.718804 — Posted: 2026-04-16
SPLIT: Safety Prioritization for Long COVID Drug Repurposing via a Causal Integrated Targeting Framework
Pinero, S. L., Li, X., Lee, S. H., Liu, L., Li, J., Le, T. D.
10.64898/2026.04.12.26350701 — Posted: 2026-04-16
Effectiveness of 2025-2026 mRNA-1283 and BNT162b2 COVID-19 Vaccines Against COVID-19 Related Hospitalizations and Medically-Attended COVID-19 Among Adults Aged >= 65 years in the United States
Vicic, N., Bogdanov, A., Hensler, H., Ryan, T., Zeng, N., Beck, E., Patry, E., Bonafede, M., Araujo, A. B., Wilson, A.
10.64898/2026.04.13.26350772 — Posted: 2026-04-16
Cognitive Profiling and Validation of a Digital Cognitive Assessment Tool in Post-COVID-19 Condition: Protocol for a Single-Center, Cross-Sectional Study (DigiCog Study)
Lacomba-Arnau, E., Da Rocha Oliveira, R., Monteiro, S., Pauly, C., Vaillant, M., Celebic, A., Bulaev, D., Fischer, A., Fagherazzi, G., Fernandez, G., Shulz, M., Perquin, M.
10.64898/2026.04.14.26350862 — Posted: 2026-04-16
Mechanistic insights into the association and activation of the SARS-CoV-2 2'-O-Methyltransferase (NSP16)
Ma, H., Brace, A., Lemus, M. R., Chennubhotla, S. C., Satchell, K. J., Ramanathan, A.
10.64898/2026.04.15.718757 — Posted: 2026-04-16
Tracing cell communication programs across conditions at single cell resolution with CCC-RISE
Ramirez, A., Thomas, N., Calabrese, D. R., Greenland, J. R., Meyer, A. S.
10.64898/2026.04.14.718551 — Posted: 2026-04-15
Risk of Post-acute Symptoms and Conditions After SARS-CoV-2 Compared to Other Respiratory Viral Infections: A Systematic Review and Meta-Analysis
Pinto, T. F., Santoro, A., Oliveira, A. L. G., Tavares, T. S., Almeida, A., Incardona, F., Marchetti, G., Cozzi-Lepri, A., Pinto, J., Caporali, J. F. M.
10.64898/2026.04.11.26350682 — Posted: 2026-04-13
Classifying and Differentiating Individuals with Respiratory Syncytial Virus, Influenza, and COVID-19 Cases in OpenSAFELY
Prestige, E., Warren-Gash, C., Quint, J. K., Evans, D., Costello, R. E., Mehrkar, A., Bacon, S., Goldacre, B., Barley-McMullen, S., Yameen, F., Shah, P., Natt, M., Alder, Y., Hulme, W., Parker, E. P. K., Eggo, R. M.
10.64898/2026.04.09.26350495 — Posted: 2026-04-13
SARS-CoV-2 Introductions into Lao PDR Revealed by Genomic Surveillance, 2021-2024
Panapruksachat, S., Troupin, C., Souksavanh, M., Keeratipusana, C., Vongsouvath, M., Vongphachanh, S., Vongsouvath, M., Phommasone, K., Somlor, S., Robinson, M. T., Chookajorn, T., Kochakarn, T., Day, N. P., Mayxay, M., Letizia, A. G., Dubot-Peres, A., Ashley, E. A., Buchy, P., Xangsayarath, P., Batty, E. M.
10.64898/2026.04.09.26349480 — Posted: 2026-04-13
Comparative LUSZ Therapeutic Study (LUSZ_AVIST) of Antiviral, Antiretroviral, and Immunosuppressive Treatments in Hospitalized COVID-19 Patients with High-Risk Factors, Biomarkers, and Disease Progression.
Makdissy, N., Makdessi, E. W., Fenianos, F., Nasreddine, N., Daher, W., El Hamoui, S.
10.64898/2026.04.10.26350587 — Posted: 2026-04-13

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).