COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,389 Articles (22,816 medRxiv, 8,573 bioRxiv)

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First-in-Human Study of a First-in-Class AI-Designed Monoclonal Antibody (GB-0669) Against the Conserved SARS-CoV-2 Spike S2 Stem Helix
Borriello, F., Koh, G. C., Troconiz, I. F., Nassirpour, R., Goyal, L., Suyundikov, A., Safder, A., Robertson, N., Allen, A., Robertson, A., Straley, S., Farmer, P., Murphy, D., Carlin, E., Schmitt, K. P., Pegu, A., Hazuda, D., Snyder, A., De Alwis, D. P.
10.1101/2025.10.07.25337449 — Posted: 2025-10-08
Evaluating Rural/Urban HPV Vaccine Completion Rates in Iowa After the COVID-19 Pandemic
Schaefer, D., Semprini, J.
10.1101/2025.10.07.25337497 — Posted: 2025-10-08
Phase 1 Study of Safety, Reactogenicity, and Immunogenicity of a Novel MVA-SARS-2-ST Vaccine Candidate Administered as Inhalation Boost in SARS-CoV-2 Immunized Adults
Hohlfeld, J. M., Hammerschmidt, S., Kayser, T., Kutschenko, A., Buchholz, A., Permanyer, M., Riemann, L., Schindler, C., Zapf, A., Badpa, M., Kraehling, V., Becker, S., Falk, C., Schroeder, S., Sutter, G., Volz, A., Foerster, R.
10.1101/2025.10.07.25337492 — Posted: 2025-10-08
Nontuberculous Mycobacteria Species in Patients with Concurrent COVID-19 and Mycobacterial Disease
Eliseev, P., Bairakova, A., Kazyulina, A., Kuznetsov, E., Samoilova, A., Vasilieva, I.
10.1101/2025.10.02.25337223 — Posted: 2025-10-07
Spatiotemporal variation of COVID-19 case time series in the United Kingdom: a dynamic time warping analysis
Kong, K. L., Shearer, F. M., Eales, O.
10.1101/2025.10.05.25337392 — Posted: 2025-10-07
Identification and characterization of a SARS-CoV-2 Mpro G23 deletion ensitrelvir-resistant mutant
Ma, Y., Ye, C., Rahisuddin, R., Mahmoud, S., Cupic, A., Khalil, A. M., Castro, E., Jackson, N., Bayoumi, M., Gupta, Y., Plemper, R. K., Martinez-Sobrido, L.
10.1101/2025.09.30.679586 — Posted: 2025-10-07
Template switching by coronavirus polymerase requires helicase activity and is stimulated by remdesivir and molnupiravir
Rakib, A., Das, A., BERA, S. C., America, P., Klein, M., Anderson, T., Marecki, J. C., Wang, B. K., Bogers, E., Feng, J., Bilello, J., Papini, F. S., Smitskamp, Q., Arnold, J. J., Artsimovitch, I., Kirchdoerfer, R., Cameron, C. E., Raney, K. D., Dulin, D.
10.1101/2025.10.03.680419 — Posted: 2025-10-06
Re-infection with SARS-CoV-2 is associated with increased antibody breadth and potency against diverse sarbecovirus strains
Lilly, M., Ruiz, F., Foreman, W., Chohan, V., Guenthoer, J., Depierreux, D., Baharani, V., Ralph, D., Harteloo, A., Chu, H., Bieniasz, P. D., Starr, T., Overbaugh, J.
10.1101/2025.10.03.679858 — Posted: 2025-10-06
SARS-CoV-2 cross-reactive B-cells outnumber seasonal coronavirus spike-specific clones at the end of the COVID-19 pandemic
Gonzalez Lopez, C., Aguilar-Bretones, M., Zhang, J., Bekki, B., van den Doel, P., van Gorp, E. C., van der Kuy, P. H. M., Haagmans, B. L., GeurtsvanKessel, C. H., Koopmans, M. P. G., de Vries, R. D., van Gils, M. J., van Nierop, G. P.
10.1101/2025.09.28.25336743 — Posted: 2025-10-05
TACO: TabPFN Augmented Causal Outcomes for Early Detection of Long COVID
Pinero, S. L., Li, X., Liu, L., Li, J., Lee, S. H., Winter, M., Nguyen, T., Zhang, J., Le, T. D.
10.1101/2025.10.02.25337138 — Posted: 2025-10-05

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Subject Areas
* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).