COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

30,790 Articles (22,523 medRxiv, 8,267 bioRxiv)

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The secretory IgA (sIgA) response in human milk against the SARS-CoV-2 Spike is highly durable and neutralizing for at least 1 year of lactation post-infection
Yang, X., Fox, A., DeCarlo, C., Pineda, N., Powell, R. L.
10.1101/2023.05.19.23290192 — Posted: 2023-05-26
Modifications to the SR-Rich Region of the SARS-CoV-2 Nucleocapsid Regulate Self-Association and Attenuate RNA Interactions
Reardon, P. N., Stuwe, H., Shah, S., Yu, Z., Hughes, K., Barbar, E.
10.1101/2023.05.26.542392 — Posted: 2023-05-26
In vitro reconstitution of SARS CoV-2 Nsp1-induced mRNA cleavage reveals the key roles of the N-terminal domain of Nsp1 and the RRM domain of eIF3g
Abaeva, I. S., Arhab, Y., Miscicka, A., Hellen, C. U. T., Pestova, T. V.
10.1101/2023.05.25.542379 — Posted: 2023-05-26
Evolution of transient RNA structure-RNA polymerase interactions in respiratory RNA virus genomes
Rigby, C. V., Sabsay, K. R., Bisht, K., Eggink, D., Jalal, H., te Velthuis, A. J. W.
10.1101/2023.05.25.542331 — Posted: 2023-05-26
Multi-omic Profiling Reveals Early Immunological Indicators for Identifying COVID-19 Progressors
Drake, K. A., Talantov, D., Tong, G., Lin, J. T., Verheijden, S., Katz, S., Leung, J. M., Yuen, B., Krishna, V., Wu, M. J., Sutherland, A., Short, S., Kheradpour, P., Mumbach, M. R., Franz, K. M., Trifonov, V., Lucas, M. V., Merson, J., Kim, C. C., The PRESCO Study Group
10.1101/2023.05.25.542297 — Posted: 2023-05-26
A Multi-Epitope/CXCL11 Prime/Pull Coronavirus Mucosal Vaccine Boosts the Frequency and the Function of Lung-Resident CD4+ and CD8+ Memory T Cells and Protects Against COVID-19-like Symptoms and Death Caused by SARS-CoV-2 infection
Zayou, L., Prakash, S., Dhanushkodi, N. R., Quadiri, A., Ibraim, I. C., Singer, M., Salem, A., Shaik, A. M., Suzer, B., Chilukuri, A., Tran, J., Nguyen, P. C., Sun, M., Hormi-Carver, K. K., Belmouden, A., Vahed, H., Ulmer, J. B., BENMOHAMED, L.
10.1101/2023.05.23.542024 — Posted: 2023-05-26
Longitudinal host transcriptional responses to SARS-CoV-2 infection in adults with extremely high viral load
Avadhanula, V., Creighton, C. J., Ferlic-Stark, L., Sucgang, R., Zhang, Y., Nagaraj, D., Nicholson, E. G., Rajan, A., Menon, V. K., Doddapaneni, H., Muzny, D. M., Metcalf, G. A., Cregeen, S. J. J., Hoffman, K. L., Gibbs, R. A., Petrosino, J. J., Piedra, P. A.
10.1101/2023.05.24.542181 — Posted: 2023-05-25
Vascular Endothelial-derived SPARCL1 Exacerbates Viral Pneumonia Through Pro-Inflammatory Macrophage Activation
Zhao, G., Gentile, M. E., Xue, L., Cosgriff, C. V., Weiner, A. I., Adams-Tzivelekidis, S., Wong, J., Li, X., Kass-Gergi, S., Holcomb, N. P., Basil, M. C., Steward, K. M., Planer, J. D., Cantu, E., Christi, J. D., Crespo, M. M., Mitchell, M. J., Meyer, N. J., Vaughan, A. E.
10.1101/2023.05.25.541966 — Posted: 2023-05-25
Dichotomy of neutralizing antibody, B cell and T cell responses to SARS-CoV-2 vaccination and protection in healthy adults
Carr, E. J., Townsley, H., Wu, M. Y., Wilkinson, K. A., Hobson, P. S., Levi, D., Namjou, S., Mears, H. V., Hobbs, A., Ragno, M., Herman, L. S., Harvey, R., Bailey, C., Fowler, A. S., Hatipoglu, E., Ngai, Y., Clayton, B., Miah, M., Bawumia, P., Miranda, M., Smith, C., Sawyer, C., Kelly, G., Mahalingasivam, V., Zheng, B., Evans, S. J., Libri, V., Riddell, A., Nicod, J., O'Reilly, N., Howell, M., Williams, B., Wilkinson, R. J., Kassiotis, G., Swanton, C., Gandhi, S., Beale, R. C., Bauer, D. L., Wall, E. C.
10.1101/2023.05.24.541920 — Posted: 2023-05-25
Cross-Protection Induced by Highly Conserved Human B, CD4+, and CD8+ T Cell Epitopes-Based Coronavirus Vaccine Against Severe Infection, Disease, and Death Caused by Multiple SARS-CoV-2 Variants of Concern
Prakash, S. F., Dhanushkodi, N. R., Zayou, L., Ibraim, I. C., Quadiri, A., Coulon, P. G., Tifrea, D. F., Suzler, B., Amin, M., Chilukuri, A., Edwards, R. A., Vahed, H., Nesburn, A. B., Kuppermann, B. D., Ulmer, J. B., Gil, D., Jones, T. M., BenMohamed, L.
10.1101/2023.05.24.541850 — Posted: 2023-05-24

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).