COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,003 Articles (22,627 medRxiv, 8,376 bioRxiv)

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Fast and scalable lipid nanoparticle formulation of niclosamide (nano NCM) effectively inhibits SARS-CoV-2 replication in vitro
Wang, G., Gaikwad, H., McCarthy, M. K., Gonzalez-Juarrero, M., Li, Y., Armstrong, M., Reisdorf, N., Morrison, T. E., Simberg, D.
10.1101/2020.12.18.423509 — Posted: 2020-12-19
SARS-CoV-2 spike protein interacts with and activates TLR4
Zhao, Y., Kuang, M., Wang, X., You, F.
10.1101/2020.12.18.423427 — Posted: 2020-12-18 Discussion: Onsite
Multi-omic profiling reveals widespread dysregulation of innate immunity and hematopoiesis in COVID-19
Wilk, A. J., Lee, M. J., Wei, B., Parks, B., Pi, R., Martinez-Colon, G. J., Ranganath, T., Zhao, N. Q., Taylor, S., Becker, W., Stanford COVID-19 Biobank, , Jimenez-Morales, D., Blomkalns, A. L., O'Hara, R., Ashley, E. A., Nadeau, K. C., Yang, S., Holmes, S., Rabinovitch, M., Rogers, A. J., Greenleaf, W. J., Blish, C. A.
10.1101/2020.12.18.423363 — Posted: 2020-12-18
assayM: a web application to monitor mutations in COVID-19 diagnostic assays.
Mohamed Ghazzali, R. N., Pain, A.
10.1101/2020.12.18.423467 — Posted: 2020-12-18
SNPnexus COVID: Facilitating the analysis of COVID-19 host genetics
Oscanoa, J., Sivapalan, L., Abdollahyan, M., Gadaleta, E., Chelala, C.
10.1101/2020.12.18.423439 — Posted: 2020-12-18
Temporal kinetics of RNAemia and associated systemic cytokines in hospitalized COVID-19 patients
van Riel, D., Embregts, C., Sips, G. J., van den Akker, J., Endeman, H., van Nood, E., van Kampen, J. J., Molenkamp, R., Koopmans, M., van de vijver, d., GeurtsvanKessel, C.
10.1101/2020.12.17.423376 — Posted: 2020-12-18
An infectivity-enhancing site on the SARS-CoV-2 spike protein is targeted by COVID-19 patient antibodies
Liu, Y., Soh, W. T., Tada, A., Arakawa, A., Matsuoka, S., Nakayama, E. E., Li, S., Ono, C., Torii, S., Kishida, K., Jin, H., Nakai, W., Arase, N., Nakagawa, A., Shindo, Y., Kohyama, M., Nakagami, H., Tomii, K., Ohmura, K., Ohshima, S., Okada, M., Matsuura, Y., Standley, D. M., Shioda, T., Arase, H.
10.1101/2020.12.18.423358 — Posted: 2020-12-18 Discussion: Onsite | Offsite
Human Surfactant Protein D Binds S1 and Receptor Binding Domain of Spike protein and acts as an entry inhibitor of SARS-CoV-2 Pseudotyped viral particles in vitro
Hsieh, M.-H., Beirag, N., Murugaiah, V., Chou, Y.-C., Kuo, W.-S., Kao, H.-F., Madan, T., Kishore, U., Wang, J.-Y.
10.1101/2020.12.18.423418 — Posted: 2020-12-18
A new concept on anti-SARS-CoV-2 vaccines: strong CD8+ T-cell immune response in both spleen and lung induced in mice by endogenously engineered extracellular vesicles
Ferrantelli, F., Chiozzini, C., Manfredi, F., Leone, P., Federico, M.
10.1101/2020.12.18.423420 — Posted: 2020-12-18
A recombinant fragment of Human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples
Madan, T., Biswas, B., Varghese, P., Subedi, R., Pandit, H., Idicula-Thomas, S., Kundu, I., Rooge, S. B., Aggarwal, R., Tripathi, D., Kaur, S., Gupta, E., Gupta, S., Kishore, U.
10.1101/2020.12.18.423415 — Posted: 2020-12-18

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).