COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,629 Articles (22,913 medRxiv, 8,716 bioRxiv)

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Bi-paratopic and multivalent human VH domains neutralize SARS-CoV-2 by targeting distinct epitopes within the ACE2 binding interface of Spike
Bracken, C. J., Lim, S. A., Solomon, P., Rettko, N. J., Nguyen, D. P., Zha, B. S., Schaefer, K., Byrnes, J. R., Zhou, J., Lui, I., Liu, J., Pance, K., QCRG Structural Biology Consortium, , Zhou, X. X., Leung, K. K., Wells, J. A.
10.1101/2020.08.08.242511 — Posted: 2020-08-10
An ultra-high affinity synthetic nanobody blocks SARS-CoV-2 infection by locking Spike into an inactive conformation
Schoof, M., Faust, B., Saunders, R. A., Sangwan, S., Rezelj, V. V., Hoppe, N., Boone, M., Billesboelle, C., Zimanyi, M., Deshpande, I., Liang, J., Anand, A. A., Dobzinski, N., Zha, B. S., Barsi-Rhyne, B., Bleyy, V., Barile-Hill, A. W., Gupta, S., Simoneau, C. R., Leon, K., White, K. M., Nock, S., Liu, Y., Krogan, N. J., Ralston, C. Y., Swaney, D. L., Garcia-Sastre, A., Ott, M., Vignuzzi, M., Quantitative Biosciences Institute (QBI) Coronavirus Research Group Structural Biology Consortium, , Walter, P., Manglik, A.
10.1101/2020.08.08.238469 — Posted: 2020-08-10 Discussion: Onsite | Offsite
The interplay of SARS-CoV-2 evolution and constraints imposed by the structure and functionality of its proteins
Jaroszewski, L., Iyer, M., Alisoltani, A., Sedova, M., Godzik, A.
10.1101/2020.08.10.244756 — Posted: 2020-08-10 Discussion: Onsite
Nonstructural protein 1 of SARS-CoV-2 is a potent pathogenicity factor redirecting host protein synthesis machinery toward viral RNA.
Yuan, S., Peng, L., Park, J. J., Hu, Y., Devarkar, S. C., Dong, M. B., Wu, S., Chen, S., Lomakin, I., Xiong, Y.
10.1101/2020.08.09.243451 — Posted: 2020-08-10
SARS-CoV-2 neutralization and serology testing of COVID-19 convalescent plasma from donors with non-severe disease
Gniadek, T. J., Thiede, J. M., Matchett, W. E., Gress, A. R., Pape, K. A., Jenkins, M. K., Menachery, V. D., Langlois, R. A., Bold, T. D.
10.1101/2020.08.07.242271 — Posted: 2020-08-10
DC/L-SIGN recognition of spike glycoprotein promotes SARS-CoV-2 trans-infection and can be inhibited by a glycomimetic antagonist
Thepaut, M., Luczkowiak, J., Vives, C., Labiod, N., Bally, I., Lasala, F., Grimoire, Y., Fenel, D., Sattin, S., Thielens, N., Schoehn, G., Bernardi, A., Delgado, R., Fieschi, F.
10.1101/2020.08.09.242917 — Posted: 2020-08-10 Discussion: Onsite
Comparative analyses of SARS-CoV-2 binding (IgG, IgM, IgA) and neutralizing antibodies from human serum samples
Mazzini, L., Martinuzzi, D., Hyseni, I., Lapini, G., Benincasa, L., Piu, P., Trombetta, C. M., Marchi, S., Razzano, I., Manenti, A., Montomoli, E.
10.1101/2020.08.10.243717 — Posted: 2020-08-10 Discussion: Offsite
High throughput detection and genetic epidemiology of SARS-CoV-2 using COVIDSeq next generation sequencing
Bhoyar, R. C., Jain, A., Sehgal, P., Divakar, M. K., Sharma, D., Imran, M., Jolly, B., Ranjan, G., Rophina, M., Sharma, S., Siwach, S., Pandhare, K., Sahoo, S., Sahoo, M., Nayak, A., Mohanty, J. N., Das, J., Bhandari, S., Mathur, S. K., Kumar, A., Sahlot, R., Rojarani, P., Vijaya Lakshmi, J., Surekha, A., Sekhar, P. C., Mahajan, S., Masih, S., Singh, P., Kumar, V., Jose, B., Mahajan, V., Gupta, V., Gupta, R., Arumugam, P., Singh, A., Nandy, A., P.V., R., Jha, R. M., Kumari, A., Gandotra, S., Rao, V., Faruq, M., Kumar, S., Reshma G, B., Varma, N. G., Shekhar Roy, S., Sengupta, A., Chattopadhyay, S., Singhal, K., Pradhan, S., Tyagi, N., Wadhwa, S., Jha, D., Naushin, S., Poojary, M., Scaria, V., Sivasubbu, S.
10.1101/2020.08.10.242677 — Posted: 2020-08-10
A Classification Approach for Predicting COVID-19 Patient Survival Outcome with Machine Learning Techniques
Osi, A. A., Dikko, H. G., Abdu, M., Ibrahim, A., Isma'il, L. A., Sarki, H., Muhammad, U., Suleiman, A. A., Sani, S. S., Ringim, M. Z.
10.1101/2020.08.02.20129767 — Posted: 2020-08-10
Petabase-scale sequence alignment catalyses viral discovery
Edgar, R. C., Taylor, J., Altman, T., Barbera, P., Meleshko, D., Lin, V., Lohr, D., Novakovsky, G., Al-Shayeb, B., Banfield, J., Korobeynikov, A., Chikhi, R., Babaian, A.
10.1101/2020.08.07.241729 — Posted: 2020-08-10

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* The Clinical Trials and Epidemiology subject categories are now closed to new submissions following the completion of bioRxiv's clinical research pilot project and launch of the dedicated health sciences server medRxiv (submit.medrxiv.org). New papers that report results of Clinical Trials must now be submitted to medRxiv. Most new Epidemiology papers also should be submitted to medRxiv, but if a paper contains no health-related information, authors may choose to submit it to another bioRxiv subject category (e.g., Genetics or Microbiology).