COVID-19 SARS-CoV-2 preprints from medRxiv and bioRxiv

31,674 Articles (22,913 medRxiv, 8,761 bioRxiv)

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ViralLink: An integrated workflow to investigate the effect of SARS-CoV-2 on intracellular signalling and regulatory pathways
Treveil, A., Bohar, B., Sudhakar, P., Gul, L., Csabai, L., Olbei, M., Poletti, M., Madgwick, M., Andrighetti, T., Hautefort, I., Modos, D., Korcsmaros, T.
10.1101/2020.06.23.167254 — Posted: 2020-06-23
Biochemical evidence of furin specificity and potential for phospho-regulation at Spike protein S1/S2 cleavage site in SARS-CoV2 but not in SARS-CoV1 or MERS-CoV
Örd, M., Faustova, I., Loog, M.
10.1101/2020.06.23.166900 — Posted: 2020-06-23
SARS-CoV-2 structure and replication characterized by in situ cryo-electron tomography
Klein, S., Cortese, M., Winter, S. L., Wachsmuth-Melm, M., Neufeldt, C. J., Cerikan, B., Stanifer, M. L., Boulant, S., Bartenschlager, R., Chlanda, P.
10.1101/2020.06.23.167064 — Posted: 2020-06-23
RAAS blockade, kidney disease, and expression of ACE2, the entry receptor for SARS-CoV-2, in kidney epithelial and endothelial cells
Subramanian, A., Vernon, K., Slyper, M., Waldman, J., Luecken, M. D., Gosik, K., Dubinsky, D., Cuoco, M., Keller, K., Purnell, J., Nguyen, L., Dionne, D., Rozenblatt-Rosen, O., Weins, A., Human Cell Atlas Lung Biological Network, , Regev, A., Greka, A.
10.1101/2020.06.23.167098 — Posted: 2020-06-23
Structure-Based Design with Tag-Based Purification and In-Process Biotinylation Enable Streamlined Development of SARS-CoV-2 Spike Molecular Probes
Zhou, T., Teng, I.-T., Olia, A. S., Cerutti, G., Gorman, J., Nazzari, A., Shi, W., Tsybovsky, Y., Wang, L., Wang, S., Zhang, B., Zhang, Y., Katsamba, P. S., Petrova, Y., Banach, B. B., Fahad, A. S., Liu, L., Lopez Acevedo, S. N., Madan, B., Oliveira de Souza, M., Pan, X., Wang, P., Wolfe, J. R., Yin, M., Ho, D. D., Phung, E., DiPiazza, A., Chang, L., Abiona, O., Corbett, K. S., DeKosky, B. J., Graham, B. S., Mascola, J. R., Misasi, J., Ruckwardt, T., Sullivan, N. J., Shapiro, L., Kwong, P. D.
10.1101/2020.06.22.166033 — Posted: 2020-06-23 Discussion: Onsite | Offsite
An Enzymatic TMPRSS2 Assay for Assessment of Clinical Candidates and Discovery of Inhibitors as Potential Treatment of COVID-19
Shrimp, J. H., Kales, S. C., Sanderson, P. E., Simeonov, A., Shen, M., Hall, M. D.
10.1101/2020.06.23.167544 — Posted: 2020-06-23
Detailed phylogenetic analysis of SARS-CoV-2 reveals latent capacity to bind human ACE2 receptor
Anderson, D. W., Brintnell, E., Gupta, M.
10.1101/2020.06.22.165787 — Posted: 2020-06-23 Discussion: Onsite
CD209L/L-SIGN and CD209/DC-SIGN act as receptors for SARS-CoV-2 and are differentially expressed in lung and kidney epithelial and endothelial cells
Amraei, R., Napoleon, M., Yin, W., Berrigan, J., Suder, E., Zhao, G., Olejnik, J., Gummuluru, S., Muhlberger, E., Chitalia, V., Rahimi, N.
10.1101/2020.06.22.165803 — Posted: 2020-06-23
A nanoluciferase SARS-CoV-2 for rapid neutralization testing and screening of anti-infective drugs for COVID-19
Shi, P.-Y., Xie, X., Muruato, A. E., Zhang, X., Lokugamage, K. G., Fontes-Garfias, C. R., Zou, J., Liu, J., Ren, P., Balakrishnan, M., Cihlar, T., Tseng, C.-T. K., Makino, S., Menachery, V. D., Bilello, J. P.
10.1101/2020.06.22.165712 — Posted: 2020-06-23
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Custodio, T. F., Das, H., Sheward, D. J., Hanke, L., Pazicky, S., Pieprzyk, J., Sorgenfrei, M., Schroer, M., Gruzinov, A., Jeffries, C., Graewert, M., Svergun, D. I., Dobrev, N., Remans, K., Seeger, M., McInerney, G. M., Murrell, B., Hällberg, B. M., Löw, C.
10.1101/2020.06.23.165415 — Posted: 2020-06-23

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