Channel:  Francis Crick Institute

1,146 Articles

Defective heart chamber growth and myofibrillogenesis after knockout of adprhl1 gene function by targeted disruption of the ancestral catalytic active site.
Smith, S. J., Towers, N., Demetriou, K., Mohun, T. J.
10.1101/2020.02.13.947424 — Posted: 2020-02-27
Apical length governs computational diversity of L5 pyramidal neurons
Galloni, A. R., Laffere, A., Rancz, E. A.
10.1101/754499 — Posted: 2020-02-18
Enteric glia as a source of neural progenitors in adult zebrafish
McCallum, S., Obata, Y., Fourli, E., Boeing, S., Peddie, C. J., Xu, Q., Horswell, S., Kelsh, R., Collinson, L., Wilkinson, D., Pin, C., Pachnis, V., Heanue, T.
10.1101/2020.02.14.949859 — Posted: 2020-02-15
Wheat pathogen Zymoseptoria tritici N-myristoyltransferase inhibitors: on-target antifungal activity and an unusual metabolic defense mechanism
Fedoryshchak, R. O., Ocasio, C. A., Strutton, B., Mattocks, J., Corran, A. J., Tate, E. W.
10.1101/2020.02.09.940536 — Posted: 2020-02-10
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation
Dimchev, G., Amiri, B., Humphries, A. C., Schaks, M., Dimchev, V., Stradal, T. E. B., Faix, J., Krause, M., Way, M., Falcke, M., Rottner, K.
10.1101/777326 — Posted: 2020-02-05
Super-Beacons: open-source probes with spontaneous tuneable blinking compatible with live-cell super-resolution microscopy
Pereira, P. M., Gustafsson, N., Marsh, M., Mhlanga, M. M., Henriques, R.
10.1101/2020.01.20.912311 — Posted: 2020-02-04
Survival of the frequent at finite population size and mutation rate: bridging the gap between quasispecies and monomorphic regimes with a simple model
Khatri, B. S.
10.1101/375147 — Posted: 2020-02-04
Patient-specific Alzheimer-like pathology in trisomy 21 cerebral organoids reveals BACE2 as a gene-dose-sensitive AD-suppressor in human brain
Alic, I., Goh, P. A., Murray, A., Portelius, E., Gkanatsiou, E., Gough, G., Mok, K. Y., Koschut, D., Brunmeir, R., Yeap, Y. J., O'Brien, N. L., Groet, J., Shao, X., Havlicek, S., Dunn, N. R., Kvartsberg, H., Brinkmalm, G., Hithersay, R., Startin, C., Hamburg, S., Phillips, M., Pervushin, K., Turmaine, M., Wallon, D., Rovelet-Lecrux, A., Soininen, H., Volpi, E., Martin, J. E., Foo, J. N., Becker, D. L., Rostagno, A., Ghiso, J., Krsnik, Z., Simic, G., Kostovic, I., Mitrecic, D., LonDownS Consortium, , Francis, P. T., Blennow, K., Strydom, A., Hardy, J., Zetterberg, H., Nizetic, D.
10.1101/2020.01.29.918037 — Posted: 2020-01-31
Pyphe: A python toolbox for assessing microbial growth and cell viability in high-throughput colony screens
Kamrad, S., Rodriguez-Lopez, M., Cotobal, C., Correia-Melo, C., Ralser, M., Bahler, J.
10.1101/2020.01.22.915363 — Posted: 2020-01-23
KAT2-mediated acetylation switches the mode of PALB2 chromatin association to safeguard genome integrity
Fournier, M., Bleuyard, J.-Y., Couturier, A. M., Ellins, J., Hester, S., Smerdon, S. J., Tora, L., Esashi, F.
10.1101/735811 — Posted: 2020-01-21

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