Channel:  Francis Crick Institute

1,146 Articles

Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes
Dentro, S. C., Leshchiner, I., Haase, K., Tarabichi, M., Wintersinger, J., Deshwar, A. G., Yu, K., Rubanova, Y., Macintyre, G., Demeulemeester, J., Vazquez-Garcia, I., Kleinheinz, K., Livitz, D. G., Malikic, S., Donmez, N., Sengupta, S., Anur, P., Jolly, C., Cmero, M., Rosebrock, D., Schumacher, S., Fan, Y., Fittall, M., Drews, R. M., Yao, X., Lee, J., Schlesner, M., Zhu, H., Adams, D. J., Getz, G., Boutros, P. C., Imielinski, M., Beroukhim, R., Sahinalp, S. C., Ji, Y., Peifer, M., Martincorena, I., Markowetz, F., Mustonen, V., Yuan, K., Gerstung, M., Spellman, P. T., Wang, W., Morris, Q. D.
10.1101/312041 — Posted: 2020-04-22
A Structure-Based Mechanism for DNA Entry into the Cohesin Ring
Higashi, T. L., Eickhoff, P., Simoes, J. S., Locke, J., Nans, A., Flynn, H. R., Snijders, A. P., Papageorgiou, G., O'Reilly, N., Chen, Z. A., O'Reilly, F. J., Rappsilber, J., Costa, A., Uhlmann, F.
10.1101/2020.04.21.052944 — Posted: 2020-04-21
The deubiquitylase USP9X controls ribosomal stalling
Clancy, A., Heride, C., Pinto-Fernandez, A., Kallinos, A., Kayser-Bricker, K., Wang, W., Smith, V., Elcocks, H., Davis, S., Fessler, S., McKinnon, C., Katz, M., Hammonds, T., Jones, N. P., O'Connell, J., Follows, B., Mischke, S., Caravella, J. A., Ioannidis, S., Dinsmore, C., Kim, S., Behrens, A., Komander, D., Kessler, B. M., Urbe, S., Clague, M. J.
10.1101/2020.04.15.042291 — Posted: 2020-04-17
A pan-cancer landscape of somatic substitutions in non-unique regions of the human genome
Tarabichi, M., Demeulemeester, J., Verfaillie, A., Flanagan, A. M., Van Loo, P., Konopka, T.
10.1101/2020.04.14.040634 — Posted: 2020-04-15
FUS gene is dual-coding with both proteins united in FUS-mediated toxicity
Brunet, M. A., Jacques, J.-F., Nassari, S., Tyzack, G. E., McGoldrick, P., Zinman, L., Jean, S., Robertson, J., Patani, R., Roucou, X.
10.1101/848580 — Posted: 2020-04-14
Co-activation of NF-κB and MYC renders cancer cells addicted to IL6 for survival and phenotypic stability
Barbosa, R., Xu, A. Q., D'Andrea, D., Copley, F., Patel, H., Chakravarty, P., Clear, A., Calaminici, M., Janz, M., Zhang, B., Schmidt-Supprian, M., Wang, J., Gribben, J., Tooze, R., Fitzgibbon, J., Franzoso, G., Rajewsky, K., Calado, D. P.
10.1101/2020.04.12.038414 — Posted: 2020-04-13
Differential protein phosphorylation affects the localisation of two secreted Toxoplasma proteins and is widespread during stage conversion
Young, J., Broncel, M., Teague, H., Russell, M. R., McGovern, O., Renshaw, M., Frith, D., Snijders, A. P., Collinson, L. M., Carruthers, V. B., Ewald, S. E., Treeck, M.
10.1101/2020.04.09.035279 — Posted: 2020-04-10
Recent evolution of a TET-controlled and DPPA3/STELLA-driven pathway of passive demethylation in mammals
Mulholland, C. B., Nishiyama, A., Ryan, J., Nakamura, R., Yigit, M., Glueck, I. M., Trummer, C., Qin, W., Bartoschek, M. D., Traube, F. R., Parsa, E., Ugur, E., Modic, M., Acharya, A., Stolz, P., Ziegenhain, C., Wierer, M., Enard, W., Carell, T., Lamb, D. C., Takeda, H., Nakanashi, M., Bultmann, S., Leonhardt, H.
10.1101/321604 — Posted: 2020-04-04
Geometric differences between nuclear envelopes of Wild-type and Chlamydia trachomatis-infected HeLa cells
Karabag, C., Jones, M. L., Peddie, C. J., Weston, A. E., Collinson, L. M., Reyes-Aldasoro, C. C.
10.1101/2020.04.02.021733 — Posted: 2020-04-02
Identification of Conserved Evolutionary Trajectories in Tumors
Hodzic, E., Shrestha, R., Malikic, S., Collins, C. C., Litchfield, K., Turajlic, S., Sahinalp, C.
10.1101/2020.03.09.967257 — Posted: 2020-04-01

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