Channel:  Francis Crick Institute

1,252 Articles

Quantitative measurement of antibiotic resistance in Mycobacterium tuberculosis reveals genetic determinants of resistance and susceptibility in a target gene approach
CRyPTIC Consortium, , Carter, J. J.
10.1101/2021.09.14.460353 — Posted: 2021-09-21
Characterisation of tumour immune microenvironment remodelling following oncogene inhibition in preclinical studies using an optimised imaging mass cytometry workflow
van Maldegem, F., Valand, K., Cole, M., Patel, H., Angelova, M., Rana, S., Colliver, E., Enfield, K., Bah, N., Tsang, V., Mugarza, E., Moore, C., Hobson, P., Levi, D., Molina, M., Swanton, C., Downward, J.
10.1101/2021.02.02.429358 — Posted: 2021-09-21
Bringing TrackMate into the era of machine-learning and deep-learning.
Ershov, D., Phan, M.-S., Pylvänäinen, J. W., Rigaud, S. U., Le Blanc, L., Charles-Orszag, A., Conway, J. R. W., Laine, R. F., Roy, N. H., Bonazzi, D., Dumenil, G., Jacquemet, G., Tinevez, J.-Y.
10.1101/2021.09.03.458852 — Posted: 2021-09-20
The master energy homeostasis regulator PGC-1alpha couples transcriptional co-activation and mRNA nuclear export
Mihaylov, S. R., Castelli, L. M., Lin, Y.-H., Gul, A., Soni, N., Hastings, C., Flynn, H. R., Dickman, M. J., Snijders, A. P., Bandmann, O., Mortiboys, H., Ultanir, S. K., Hautbergue, G. M.
10.1101/2021.09.19.460961 — Posted: 2021-09-19
Genome-wide association studies of global Mycobacterium tuberculosis resistance to thirteen antimicrobials in 10,228 genomes
Earle, S. G., Wilson, D. J., The CRyPTIC Consortium
10.1101/2021.09.14.460272 — Posted: 2021-09-16
Chromatin-contact atlas reveals disorder-mediated protein interactions and moonlighting chromatin-associated RBPs
Rafiee, M.-r., Zagalak, J., Sidorov, S., Steinhauser, S., Davey, K., Ule, J., Luscombe, N. M.
10.1101/2020.07.13.200212 — Posted: 2021-09-16
Comprehensive analysis of DNA replication timing in genetic diseases and gene knockouts identifies MCM10 as a novel regulator of the replication program
Caballero, M., Ge, T., Rebelo, A. R., Seo, S., Kim, S., Brooks, K., Zuccaro, M. V., Kanagaraj, R., Vershkov, D., Kim, D., Smogorzewska, A., Smolka, M. B., Benvenisty, N., West, S. C., Egli, D. C., Mace, E. M., Koren, A.
10.1101/2021.09.08.459433 — Posted: 2021-09-15
Cdc6 is sequentially regulated by PP2A-Cdc55, Cdc14 and Sic1 for origin licensing in S. cerevisiae
Philip, J., Ord, M., Silva, A., Singh, S., Diffley, J. F. X., Remus, D., Loog, M., Ikui, A. E.
10.1101/2021.09.14.460335 — Posted: 2021-09-15
Chromodomain protein regulates the expression of a subset of RIFINs in P. falciparum
Sethumadhavan, D. V., Tiburcio, M., Kanyal, A., Jabeena, C., Govindaraju, G., Karmodiya, K., Rajavelu, A.
10.1101/2021.09.13.460021 — Posted: 2021-09-13
BashTheBug: a crowd of volunteers reproducibly and accurately measure the minimum inhibitory concentrations of 13 antitubercular drugs from photographs of 96-well broth microdilution plates.
Fowler, P. W., Wright, C., Spiers, H., Zhu, T., Baeten, E. M., Hoosdally, S. W., Gibertoni Cruz, A. L., Roohi, A., Kouchaki, S., Walker, T. M., Peto, T. E., Miller, G., Lintott, C., Clifton, D., Crook, D. W., Walker, A. S., The Zooniverse Volunteer Community, , The CRyPTIC Consortium
10.1101/2021.07.20.453060 — Posted: 2021-09-13

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