Channel:  Francis Crick Institute

1,146 Articles

Developmental regulation of neuronal gene expression by Elongator complex protein 1 dosage.
Morini, E., Gao, D., Logan, E. M., Salani, M., Krauson, A. J., Chekuri, A., Chen, Y.-T., Ragavendran, A., Chakravarty, P., Erdin, S., Stortchevoi, A., Svejstrup, J. Q., Talkowski, M. E., Slaugenhaupt, S. A.
10.1101/2021.04.16.440179 — Posted: 2021-04-16
A suite of activity-based probes to dissect the KLK activome in drug-resistant prostate cancer
Lovell, S., Zhang, L., Kryza, T., Neodo, A., Bock, N., Williams, E. D., Engelsberger, E., Xu, C., Bakker, A. T., De Vita, E., Maneiro, M., Tanaka, R. J., Bevan, C. L., Clements, J. A., Tate, E. W.
10.1101/2021.04.15.439906 — Posted: 2021-04-15
Single-shot phase contrast microscopy using polarisation-resolved differential phase contrast
Kalita, R., Flanagan, W., Lightley, J., Kumar, S., Alexandrov, Y., Garcia, E., Hintze, M., Barkoulas, M., Dunsby, C., French, P. M. W.
10.1101/2021.04.14.437846 — Posted: 2021-04-14
Single cell transcriptome profiling of the human developing spinal cord reveals a conserved genetic programme with human specific features
Rayon, T., Maizels, R. J., Barrington, C., Briscoe, J.
10.1101/2021.04.12.439474 — Posted: 2021-04-12
Multiple 9-1-1 complexes promote homolog synapsis, DSB repair, and ATR signaling during mammalian meiosis
Pereira, C., Arroyo-Martinez, G. A., Guo, M. Z., Kelly, E. R., Grive, K. J., Mahadevaiah, S. K., Sims, J., Faca, V. M., Tsai, C., Schiltz, C. J., Wit, N., Jacobs, H., Clark, N. L., Freire, R., Turner, J., Lyndaker, A. M., Brieno-Enriquez, M. A., Cohen, P. E., Smolka, M. B., Weiss, R. S.
10.1101/2021.04.09.439198 — Posted: 2021-04-10
Rad53 checkpoint kinase regulation of DNA replication fork rate via Mrc1 phosphorylation
McClure, A. W., Diffley, J.
10.1101/2021.04.09.439171 — Posted: 2021-04-10
Image-based deep learning reveals the responses of human motor neurons to stress and ALS
Verzat, C., Harley, J., Patani, R., Luisier, R.
10.1101/2021.04.08.439054 — Posted: 2021-04-09
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of nsp5 Main Protease
Basier, C., Beale, R., Bineva-Todd, G., Canal, B., Curran, J. F., Deegan, T. D., Diffley, J. F., Fujisawa, R., Howell, M., Joshi, D., Labib, K., Lim, C. T., Milligan, J., Nagaraj, H., O'Reilly, N., Papageorgiou, G., Soudy, C., Tan, K. W., Ulferts, R., Weissmann, F., Wu, M., Zeisner, T. U.
10.1101/2021.04.07.438806 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp13 Helicase
Beale, R., Bertolin, A. P., Borg, A., Canal, B., Diffley, J. F., Drury, L. S., Harvey, R., Howell, M., Hussain, S., Kjaer, S., McCauley, J., McCoy, L., Milligan, J., Posse, V., Roustan, C., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438808 — Posted: 2021-04-08
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease
Beale, R., Bertolin, A. P., Canal, B., Deegan, T. D., Diffley, J. F., Drury, L. S., Fujisawa, R., Howell, M., Labib, K., McClure, A. W., Ulferts, R., Weissmann, F., Wu, M., Zeng, J.
10.1101/2021.04.07.438811 — Posted: 2021-04-08

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