Channel:  Francis Crick Institute

1,146 Articles

Single-cell transcriptional dynamics in a living vertebrate
Eck, E., Moretti, B., Schlomann, B. H., Bragantini, J., Lange, M., Zhao, X., VijayKumar, S., Valentin, G., Loureiro, C., Franco, P. P., Jollivet, C., Motomochi, B., Royer, L. A., Oates, A. C., Garcia, H. G.
10.1101/2024.01.03.574108 — Posted: 2025-06-11
Subclonal mutation load predicts survival and response to immunotherapy in cancers with low to moderate tumor mutation burden
Jiang, Y., Montierth, M. D., Yu, K., Ji, S., Tran, Q., Liu, X., Shen, J. P., Guo, S., Wu, A., Dai, Y., Shin, S. J., Li, R., Cao, S., Tang, Y., Lesluyes, T., Kopetz, S., Msaouel, P., Sood, A. K., Devonshire, G., Jones, C. M., Ajani, J., Subudhi, S. K., Aparicio, A., Sharma, P., Shen, J. P., Kimmel, M., Wang, J. R., Tarabichi, M., Fitzgerald, R. C., Zhu, H., Loo, P. V., Wang, W.
10.1101/2024.07.03.601939 — Posted: 2025-06-10
MRTF-dependent cytoskeletal dynamics drive efficient cell cycle progression
Nielsen, J. C., Benito-Jardon, M., Petrela, N. C., Diring, J., Bellamy, S., Treisman, R.
10.1101/2025.06.06.657372 — Posted: 2025-06-07
Multimodal profiling unveils a reversible basal-like breast cancer cell state resistant to AKT inhibition
Ratcliffe, C. D. H., Sparks, H., Boezio, G. L. M., Alexandrov, Y., Jenkins, R. P., Le Marois, A., Soro-Barrio, P., Lee, R., Strohbuecker, S., Joshi, S., Ellis, J. K., Fortier, A.-M., Gustafsson, N., Cunha, A. C., Park, M., MacRae, J. I., Serio, A., Briscoe, J., Riddell, A., Barry, S. T., Dunsby, C., Sahai, E.
10.1101/2025.06.06.658331 — Posted: 2025-06-07
Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
Gazzara, E., Adrover, J. M., Lui, A., Han, S., Aminzada, Z., Bhandari, N., Sivetz, N., Shirue, V. S., Shergill, B. S., Curtis, M. B., George, S. C., Cicala, A., Rishi, A., Chung, C., Devoe, C., Huang, H., Weiss, M., Lou, E., Tuveson, D. A., Beyaz, S., Westcott, P. M. K., Egeblad, M., Gholami, S.
10.1101/2025.05.30.657122 — Posted: 2025-06-07
A closed feedback between tissue phase transitions and morphogen gradients drives patterning dynamics
Autorino, C., Khoromskaia, D., Harari, L., Floris, E., Booth, H., Pallares-Cartes, C., Petrasiunaite, V., Dorrity, M., Corominas-Murtra, B., Hadjivasiliou, Z., Petridou, N.
10.1101/2025.06.06.658228 — Posted: 2025-06-06
C9orf72 polyGA knock-in mice exhibit mild motor and proteomic changes consistent with ALS/FTD
Milioto, C., Carcole, M., Zanovello, M., Ahmed, M., Nirujogi, R. S., Biggs, D., Katona, E., Glaria, I., Santos, A., Devoy, A., Fratta, P., Alessi, D. R., Davies, B., Greensmith, L., Fisher, E., Isaacs, A. M.
10.1101/2025.05.30.656994 — Posted: 2025-06-02
Beneficial and detrimental consequences of AHR activation in intestinal infection
Diaz, O. P., zhou, L., Barrington, C., Lindquist, D., Graelmann, F., Wincent, E., Stockinger, B.
10.1101/2025.05.28.656570 — Posted: 2025-06-01
Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
Goldsworthy, S., Fertan, E., Dyal, P., Domoney, S., Livesey, F., Klenerman, D., Patani, R., Hung, C.
10.1101/2025.05.27.656416 — Posted: 2025-06-01
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Roeselova, A., Shivakumaraswamy, S., Jurkeviciute, G., He, J.-Z., Auburger, J., Schmitt, J., Kramer, G., Bukau, B., Enchev, R. I., Balchin, D.
10.1101/2025.05.27.656346 — Posted: 2025-05-30

RSS  Channel RSS