Channel:  Francis Crick Institute

1,121 Articles

Targeting Neutrophil Extracellular Traps to inhibit Colon Cancer Tumor Necrosis and Metastasis
Gazzara, E., Adrover, J. M., Lui, A., Han, S., Aminzada, Z., Bhandari, N., Sivetz, N., Shirue, V. S., Shergill, B. S., Curtis, M. B., George, S. C., Cicala, A., Rishi, A., Chung, C., Devoe, C., Huang, H., Weiss, M., Lou, E., Tuveson, D. A., Beyaz, S., Westcott, P. M. K., Egeblad, M., Gholami, S.
10.1101/2025.05.30.657122 — Posted: 2025-06-03
C9orf72 polyGA knock-in mice exhibit mild motor and proteomic changes consistent with ALS/FTD
Milioto, C., Carcole, M., Zanovello, M., Ahmed, M., Nirujogi, R. S., Biggs, D., Katona, E., Glaria, I., Santos, A., Devoy, A., Fratta, P., Alessi, D. R., Davies, B., Greensmith, L., Fisher, E., Isaacs, A. M.
10.1101/2025.05.30.656994 — Posted: 2025-06-02
Beneficial and detrimental consequences of AHR activation in intestinal infection
Diaz, O. P., zhou, L., Barrington, C., Lindquist, D., Graelmann, F., Wincent, E., Stockinger, B.
10.1101/2025.05.28.656570 — Posted: 2025-06-01
Lysosomal stress induces amyloid-β aggregate release and reactive transformation in human astrocytes
Goldsworthy, S., Fertan, E., Dyal, P., Domoney, S., Livesey, F., Klenerman, D., Patani, R., Hung, C.
10.1101/2025.05.27.656416 — Posted: 2025-06-01
The ribosome synchronizes folding and assembly to promote oligomeric protein biogenesis
Roeselova, A., Shivakumaraswamy, S., Jurkeviciute, G., He, J.-Z., Auburger, J., Schmitt, J., Kramer, G., Bukau, B., Enchev, R. I., Balchin, D.
10.1101/2025.05.27.656346 — Posted: 2025-05-30
The penetrant chordoid glioma PRKCA mutation is an oncogenic gain-of-function kinase inactivation eliciting early onset chondrosarcoma in mice.
Calleja, v., Henry, J. C., Cobbaut, M., Sewell, J., Rizzoti, K., Houghton, F., Boeing, S., Anyanwu, N., Varsani-Brown, S., Snoeks, T., Suarez-Bonnet, A., Priestnall, S. L., McDonald, N. Q., Cameron, A. J., Parker, P. J.
10.1101/2025.05.28.656646 — Posted: 2025-05-29
Gene network architecture, mutation and selection collectively drive developmental pattern evolvability and predictability
Booth, H., Hadjivasiliou, Z.
10.1101/2024.12.23.630099 — Posted: 2025-05-29
Dynamic Landscape Analysis of Cell Fate Decisions: Predictive Models of Neural Development From Single-Cell Data
Fontaine, M., Vives, M. J. D., Saez, M., Maizels, R., Finnie, E., Briscoe, J., Rand, D. A.
10.1101/2025.05.28.656648 — Posted: 2025-05-28
MitoTracker transfers from astrocytes to neurons independently of mitochondria
Hole, K. L., Norkett, R., Russell, E., Strom, M., Howden, J. H., Corbett, N. J., Brownlees, J., Devine, M. J.
10.1101/2025.05.27.655523 — Posted: 2025-05-28
Disease-attenuated pneumococcal biosynthesis gene mutants invade the mucosal epithelium and induce innate immunity
Weight, C. M., Pollara, G. M., Betts, M., Ragazzini, R., Connor, M., Ramos-Sevillano, E., Reine, J., Whelan, M., Guerra-Assuncao, J. A., Bonfanti, P., Jolly, C., Noursadeghi, M., Ferreira, D., Brown, J., Heyderman, R. S.
10.1101/2023.06.15.545009 — Posted: 2025-05-26

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