Channel:  Francis Crick Institute

1,146 Articles

Blimp-1 and c-Maf regulate common and unique gene networks to protect against distinct pathways of pathobiont-induced colitis
Alvarez-Martinez, M., Cox, L. S., Pearson, C. F., Branchett, W. J., Chakravarty, P., Wu, X., Slawinski, H., Al Dibouni, A., Samelis, V., Gabrysova, L., Priestnall, S. L., Suarez-Bonnet, A., Mikolajczak, A., Briscoe, J., Powrie, F., O'Garra, A.
10.1101/2023.09.14.557705 — Posted: 2023-09-16
GOT1 primes the cellular response to hypoxia by supporting glycolysis and HIF1α stabilisation
Grimm, F., Asuaje, A., Jain, A., Silva dos Santos, M., Kleinjung, J., Nunes, P. M., Gehrig, S., Fets, L., MacRae, J., Anastasiou, D.
10.1101/2023.09.06.556522 — Posted: 2023-09-08
The ALS/FTD-related C9orf72 hexanucleotide repeat expansion forms RNA condensates through multimolecular G-quadruplexes
Raguseo, F., Huyghebaert, A., Li, J., Balendra, R., Petric Howe, m., Wang, Y., Vadukul, D. M., Tanase, D., Maher, T. E., Malouf, L., Rubio Sanchez, R., Aprile, F. A., Elani, Y., Patani, R., Di Michele, L., Di Antonio, M.
10.1101/2023.01.31.526399 — Posted: 2023-09-04
SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy
Dembitz, V., Lawson, H., Burt, R., Philippe, C., James, S. C., Atkinson, S., Durko, J., Wang, L. M., Campos, J., Magee, A. M., Woodley, K., Austin, M. J., Rio-Machin, A., Casado-Izquierdo, P., Bewicke-Copley, F., Rodriguez, G., Pereira, D., Oudejans, L., Boet, E., von Kriegsheim, A., Schwaller, J., Finch, A. J., Pate, B., Sarry, J.-E., Tamburini, J., Schuringa, J. J., Hazlehurst, L., Copland, J. A., Yuneva, M., Peck, B., Cutillas, P., Fitzgibbon, J., Rouault-Pierre, K., Kranc, K., Gallipoli, P.
10.1101/2023.08.02.551656 — Posted: 2023-09-04
Evolution of chromosome arm aberrations in breast cancer through genetic network rewiring
Kuzmin, E., Baker, T. M., Lesluyes, T., Monlong, J., Abe, K. T., Coelho, P. P., Schwartz, M., Zou, D., Morin, G., Pacis, A., Yang, Y., Martinez, C., Barber, J., Kuasne, H., Li, R., Bourgey, M., Fortier, A.-M., Davison, P. G., Omeroglu, A., Guiot, M. C., Morris, Q., Kleinman, C. L., Huang, S., Gingras, A.-C., Ragoussis, I., Bourque, G., Van Loo, P., Park, M.
10.1101/2023.06.10.544434 — Posted: 2023-09-02
Unanticipated interacting features of human gut-associated lymphoid tissues link microbiota, intestinal immunity and autoimmunity
Montorsi, L., Pitcher, M. J., Zhao, Y., Demonti, A., Tull, T. J., Dionisi, C., Dhami, P., Ellis, R. J., Bishop, C., Sanderson, J., Jain, S., D'Cruz, D., Gibbons, D., Winkler, T. H., Bemark, M., Ciccarelli, F. D., Spencer, J.
10.1101/2023.08.29.555265 — Posted: 2023-08-31
Analysis of CDPK1 targets identifies a trafficking adaptor complex that regulates microneme exocytosis in Toxoplasma
Chan, A. W., Broncel, M., Yifrach, E., Haseley, N. R., Chakladar, S., Andree, E., Herneisen, A. L., Shortt, E., Treeck, M., Lourido, S.
10.1101/2023.01.11.523553 — Posted: 2023-08-29
Flow: a web platform and open database to analyse, store, curate and share bioinformatics data at scale
Capitanchik, C., Ireland, S., Harston, A., Cheshire, C., Jones, D. M., Lee, F. C. Y., Ruiz de los Mozos, I., Iosub, I. A., Kuret, K., Faraway, R., Wilkins, O. G., Arora, R., Hallegger, M., Modic, M., Chakrabarti, A. M., Luscombe, N. M., Ule, J.
10.1101/2023.08.22.544179 — Posted: 2023-08-29
Defective cytoskeletal dynamics underlies the essential role of MRTF-SRF in IL-2 delivery to CD8+ T cells during infectious challenge
Maurice, D., Costello, P., Gualdrini, F., Frederico, B., Treisman, R.
10.1101/2023.08.26.554941 — Posted: 2023-08-27
FOXL2 interaction with different binding partners regulates the dynamics of ovarian development
Migale, R., Neumann, M., Mitter, R., Rafiee, M.-R., Wood, S., Olsen, J., Lovell-Badge, R.
10.1101/2023.04.14.536403 — Posted: 2023-08-24

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