Channel:  Francis Crick Institute

1,146 Articles

Mutations in PSEN1 predispose inflammation in an astrocyte model of familial Alzheimer's disease through disrupted regulated intramembrane proteolysis
Ziff, O. J., Jolly, S., Casey, J. M., Granat, L., Samra, S., Seto-Salvia, N., Alatza, A., Phadke, L., Galet, B., Ravassard, P., Potier, M.-C., Fox, N. C., Hardy, J., Salih, D., Whiting, P., Ducotterd, F., Patani, R., Wray, S., Arber, C.
10.1101/2024.09.09.611621 — Posted: 2024-09-13
An integrated stress response-independent role of GCN2 prevents excessive ribosome biogenesis and mRNA translation
Roman-Trufero, M., Kleijn, I. T., Blighe, K., Zhou, J., Saavedra-Garcia, P., Gaffar, A., Christoforou, M., Bellotti, A., Abrahams, J., Atrih, A., Lamont, D. J., Gierlinski, M., Jayaprakash, P., Michel, A. M., Aboagye, E., Yuneva, M., Masson, G. R., Shahrezaei, V., Auner, H. W.
10.1101/2024.09.10.611650 — Posted: 2024-09-13
PACESS: Practical AI-based Cell Extraction and Spatial Statistics for large 3D bone marrow tissue images
Adams, G., Tissot, F., Liu, C., Brunsdon, C., Duffy, K., Lo Celso, C.
10.1101/2022.12.29.521787 — Posted: 2024-09-12
Subtype-specific Patterns of Evolution and Clinically Relevant Genomic Instability in Wilms Tumour
Cresswell, G. D., Chagtai, T., Al-Saadi, R., Treger, T. D., Madhan, G., Mifsud, B., Vujanic, G., Williams, R. D., Luscombe, N. M., Pritchard-Jones, K., Mifsud, W.
10.1101/2024.09.04.610994 — Posted: 2024-09-10
In vivo CRISPR screens identify GRA12 as a transcendent secreted virulence factor across Toxoplasma gondii strains and mouse subspecies
Torelli, F., Butterworth, S. W., Lockyer, E. J., Song, O.-R., Pearson-Farr, J., Treeck, M.
10.1101/2024.09.10.611481 — Posted: 2024-09-10
Human DNA replication initiation sites are specified epigenetically by oxidation of 5-methyl-deoxycytidine
Krude, T., Bi, J., Doran, R., Jones, R. A., Smith, J. C.
10.1101/2024.09.06.611651 — Posted: 2024-09-07
Dynamics of positional information in the vertebrate neural tube
Markovic, A., Briscoe, J., Page, K. M.
10.1101/2024.07.01.601514 — Posted: 2024-09-06
The cis-regulatory logic integrating spatial and temporal patterning in the vertebrate neural tube
Zhang, I., Boezio, G. L., Cornwall-Scoones, J., Frith, T., Jiang, M., Howell, M., Lovell-Badge, R., Sagner, A., Briscoe, J., Delas, M. J.
10.1101/2024.04.17.589864 — Posted: 2024-09-04
Malaria parasites undergo a rapid and extensive metamorphosis after invasion of the host erythrocyte
Freville, A., Moreira-Leite, F., Roussel, C., Russell, M. R. G., Fricot, A., Carret, V., Sissoko, A., Hayes, M. J., Dialo, A. B., Kerkhoven, N., Ressurreicao, M., Dokmak, S., Blackman, M., Collinson, L., Buffet, P. A., Vaughan, S., Ndour, A., van Ooij, C.
10.1101/2024.09.03.610831 — Posted: 2024-09-03
M. tuberculosis invades and disrupts the blood-brain barrier directly to initiate meningitis
Proust, A., Wilkinson, K. A., Wilkinson, R. J.
10.1101/2024.08.30.610462 — Posted: 2024-08-30

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