bioRxiv Channel: Institut Pasteur
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This feed contains articles for bioRxiv Channel "Institut Pasteur"
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Genomic architecture of human neuroanatomical diversity
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https://biorxiv.org/cgi/content/short/001198v1?rss=1"
Roberto ToroJean-Baptiste PolineGuillaume HuguetEva LothVincent FrouinTobias BanaschewskiGareth J BarkerArun BokdeChristian BüchelFabiana CarvalhoPatricia ConrodMira Fauth-BühlerHerta FlorJürgen GallinatHugh GaravanPenny GowloanAndreas HeinzBernd IttermannClaire LawrenceHervé LemaîtreKarl MannFrauke NeesTomá PausZdenka PausovaMarcella RietschelTrevor RobbinsMichael SmolkaAndreas StröhleGunter SchumannThomas Bourgeron2013-12-10doi:10.1101/001198Cold Spring Harbor Laboratory Press2013-12-10
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Neuroanatomical diversity of corpus callosum and brain volume in the Autism Brain Imaging Data Exchange (Abide) project
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https://biorxiv.org/cgi/content/short/002691v1?rss=1"
Aline LefebvreAnita BeggiatoThomas BourgeronRoberto Toro2014-02-14doi:10.1101/002691Cold Spring Harbor Laboratory Press2014-02-14
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Social communication in mice – Are there optimal cage conditions?
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https://biorxiv.org/cgi/content/short/011783v1?rss=1"
Allain-Thibeault FERHATAnne-Marie Le SourfdFabrice de ChamontJean-Christophe Olivo- MarinThomas BourgeronElodie Ey2014-11-26doi:10.1101/011783Cold Spring Harbor Laboratory Press2014-11-26
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Mechanical morphogenesis and the development of neocortical organisation
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https://biorxiv.org/cgi/content/short/021311v1?rss=1"
Ophélie FoubetRoberto Toro2015-06-23doi:10.1101/021311Cold Spring Harbor Laboratory Press2015-06-23
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SARTools: a DESeq2- and edgeR-based R pipeline for comprehensive differential analysis of RNA-Seq data
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https://biorxiv.org/cgi/content/short/021741v1?rss=1"
Hugo VaretJean-Yves CoppéeMarie-Agnès Dillies2015-06-30doi:10.1101/021741Cold Spring Harbor Laboratory Press2015-06-30
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Common and phylogenetically widespread coding for peptides by bacterial small RNAs
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https://biorxiv.org/cgi/content/short/030619v1?rss=1"
Robin C FriedmanStefan KalkhofOlivia Doppelt-AzeroualStephan MuellerMartina ChovancovaMartin von BergenBenno Schwikowski2015-11-04doi:10.1101/030619Cold Spring Harbor Laboratory Press2015-11-04
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Identification of protein secretion systems in bacterial genomes
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https://biorxiv.org/cgi/content/short/031039v1?rss=1"
Sophie S AbbyJean CuryJulien GuglielminiBertrand NéronMarie TouchonEduardo PC Rocha2015-11-09doi:10.1101/031039Cold Spring Harbor Laboratory Press2015-11-09
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Zika virus, a new threat for Europe?
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https://biorxiv.org/cgi/content/short/048454v1?rss=1"
Henri JUPILLEGoncalo SEIXASLaurence MOUSSONCarla SOUSAAnna-Bella FAILLOUX2016-04-13doi:10.1101/048454Cold Spring Harbor Laboratory Press2016-04-13
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Discovery of flavivirus-derived endogenous viral elements in two Anopheles mosquito genomes supports the existence of Anopheles-associated insect-specific flaviviruses
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https://biorxiv.org/cgi/content/short/064907v1?rss=1"
Sebastian LequimeLouis Lambrechts2016-09-19doi:10.1101/064907Cold Spring Harbor Laboratory Press2016-09-19
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Detection and characterization of low and high genome coverage regions using an efficient running median and a double threshold approach.
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https://biorxiv.org/cgi/content/short/092478v1?rss=1"
Desvillechabrol, D.Bouchier, C.Kennedy, S.Cokelaer, T.2016-12-08doi:10.1101/092478Cold Spring Harbor Laboratory Press2016-12-08
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Choreography of budding yeast chromosomes during the cell cycle
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https://biorxiv.org/cgi/content/short/096826v1?rss=1"
Lazar-Stefanita, L.Scolari, V.Mercy, G.Thierry, A.Muller, H.Mozziconacci, J.Koszul, R.2016-12-30doi:10.1101/096826Cold Spring Harbor Laboratory Press2016-12-30
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Meta-analysis of the variance ratio
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https://biorxiv.org/cgi/content/short/104695v1?rss=1"
Traut, N.2017-01-31doi:10.1101/104695Cold Spring Harbor Laboratory Press2017-01-31
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Cerebellar volume in autism: Meta-analysis and analysis of the ABIDE cohort
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https://biorxiv.org/cgi/content/short/104984v1?rss=1"
Traut, N.Beggiato, A.Bourgeron, T.Delorme, R.Rondi-Reig, L.Paradis, A.-L.Toro, R.2017-02-01doi:10.1101/104984Cold Spring Harbor Laboratory Press2017-02-01
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PhageTerm: a Fast and User-friendly Software to Determine Bacteriophage Termini and Packaging Mode using randomly fragmented NGS data
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https://biorxiv.org/cgi/content/short/108100v1?rss=1"
Garneau, J. R.Depardieu, F.Fortier, L.-C.Bikard, D.Monot, M.2017-02-15doi:10.1101/108100Cold Spring Harbor Laboratory Press2017-02-15
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A framework to identify modifier genes in patients with Phelan-McDermid syndrome
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https://biorxiv.org/cgi/content/short/117978v1?rss=1"
Tabet, A.-C.Rolland, T.Ducloy, M.Levy, J.Buratti, J.Mathieu, A.Haye, D.Perrin, L.Dupont, C.Passemard, S.Capri, Y.Verloes, A.Drunat, S.Keren, B.Mignot, C.Marey, I.Jacquette, A.Whalen, S.Pipiras, E.Benzacken, B.Chantot-Bastaraud, S.Afenjar, A.Heron, D.Le Caignec, C.Beneteau, C.Pichon, O.Isidor, B.David, A.Dupont, J.-M.Kemeny, S.Gouas, L.Vago, P.Mosca-Boidron, A.-L.Faivre, L.Missirian, C.Philip, N.Sanlaville, D.Edery, P.Satre, V.Coutton, C.Devillard, F.Dieterich, K.Vuillaume, M.-L.Rooryck, C.Lacombe, D.Pinso2017-03-18doi:10.1101/117978Cold Spring Harbor Laboratory Press2017-03-18
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Uncovering The Repertoire Of Endogenous Flaviviral Elements In Aedes Mosquito Genomes
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https://biorxiv.org/cgi/content/short/124032v1?rss=1"
Suzuki, Y.Frangeul, L.Dickson, L. B.Blanc, H.Verdier, Y.Vinh, J.Lambrechts, L.Saleh, M.-C.2017-04-04doi:10.1101/124032Cold Spring Harbor Laboratory Press2017-04-04
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The demographic history and mutational load of African hunter-gatherers and farmers
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https://biorxiv.org/cgi/content/short/131219v1?rss=1"
Lopez, M.Kousathanas, A.Quach, H.Harmant, C.Mouguiama-Daouda, P.Hombert, J.-M.Froment, A.Perry, G. H.Barreiro, L. B.Verdu, P.Patin, E.Quintana-Murci, L.2017-04-26doi:10.1101/131219Cold Spring Harbor Laboratory Press2017-04-26
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Integrative And Conjugative Elements And Their Hosts: Composition, Distribution, And Organization
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https://biorxiv.org/cgi/content/short/135814v1?rss=1"
Cury, J.Touchon, M.Rocha, E. P. C.2017-05-09doi:10.1101/135814Cold Spring Harbor Laboratory Press2017-05-09
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Identifying Parameters Of Host Cell Vulnerability During Salmonella Infection By Quantitative Image Analysis And Modeling
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https://biorxiv.org/cgi/content/short/139048v1?rss=1"
Voznica, J.Gardella, C.Belotserkovsky, I.Dufour, A.Enninga, J.Stevenin, V.2017-05-17doi:10.1101/139048Cold Spring Harbor Laboratory Press2017-05-17
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Experimenting with reproducibility in bioinformatics
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https://biorxiv.org/cgi/content/short/143503v1?rss=1"
Kim, Y.-M.Poline, J.-B.Dumas, G.2017-06-20doi:10.1101/143503Cold Spring Harbor Laboratory Press2017-06-20
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ICM conversion to epiblast by FGF/ERK inhibition is limited in time and requires transcription and protein degradation
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https://biorxiv.org/cgi/content/short/157537v1?rss=1"
Bessonnard, S.Coqueran, S.Vandormael-Pournin, S.Dufour, A.Artus, J.Cohen-Tannoudji, M.2017-06-29doi:10.1101/157537Cold Spring Harbor Laboratory Press2017-06-29
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Sequanix: A Dynamic Graphical Interface for Snakemake Workflows
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https://biorxiv.org/cgi/content/short/162701v1?rss=1"
Desvillechabrol, D.Legendre, R.Rioualen, C.Bouchier, C.van Helden, J.Kennedy, S.Cokelaer, T.2017-07-12doi:10.1101/162701Cold Spring Harbor Laboratory Press2017-07-12
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Engineered CRISPR-Cas9 system enables noiseless, fine-tuned and multiplexed repression of bacterial genes
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https://biorxiv.org/cgi/content/short/164384v1?rss=1"
Vigouroux, A.Oldewurtel, E.Cui, L.van Teeffelen, S.Bikard, D.2017-07-18doi:10.1101/164384Cold Spring Harbor Laboratory Press2017-07-18
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GDSCTools for Mining Pharmacogenomic Interactions in Cancer
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https://biorxiv.org/cgi/content/short/166223v1?rss=1"
Cokelaer, T.Chen, E.Iorio, F.Menden, M. P.Lightfoot, H.Saez-Rodriguez, J.Mathew, G. J.2017-07-20doi:10.1101/166223Cold Spring Harbor Laboratory Press2017-07-20
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Redesigning chromosomes to optimize conformation capture (Hi-C) assays
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https://biorxiv.org/cgi/content/short/169847v1?rss=1"
Muller, H.Scolari, V.Mercy, G.Agier, N.Descorps-Declere, S.Fischer, G.Mozziconacci, J.Koszul, R.2017-07-28doi:10.1101/169847Cold Spring Harbor Laboratory Press2017-07-28
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Inhibition of NHEJ repair by type II-A CRISPR-Cas systems
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https://biorxiv.org/cgi/content/short/170647v1?rss=1"
Bernheim, A.Calvo Villamanan, A.Basier, C.Rocha, E. P. C.Touchon, M.Bikard, D.2017-08-01doi:10.1101/170647Cold Spring Harbor Laboratory Press2017-08-01
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Numerous cultivated and uncultivated viruses encode ribosomal proteins
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https://biorxiv.org/cgi/content/short/174177v1?rss=1"
Mizuno, C. M.Guyomar, C.Roux, S.Lavigne, R.Rodriguez-Valera, F.Sullivan, M.Gillet, R.Forterre, P.Krupovic, M.2017-08-09doi:10.1101/174177Cold Spring Harbor Laboratory Press2017-08-09
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Identification of environmental and genetic factors important for Cryptococcus neoformans titan cell formation using new in vitro inducing conditions
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https://biorxiv.org/cgi/content/short/191668v1?rss=1"
10 {micro}m and up to 100 {micro}m). We found and optimized in vitro conditions that produce titan cells in order to identify the ancestry of titan cells, the environmental determinants, and the key gene regulators of titan cell formation. Titan cells generated in vitro harbor the main characteristics of titan cells produced in vivo including their large cell size (>10 {micro}m), polyploidy with a single nucleus, large vacuole, dense capsule, and thick cell wall. Here we show titan cells derived from the enlargement of progenitor cells in the population independent of yeast growth rate. Change in the incubation medium, hypoxia, nutrient starvation and low pH were the main factors that trigger titan cell formation, while quorum sensing factors like the initial inoculum concentration, pantothenic acid, and the quorum sensing peptide Qsp1p also impacted titan cell formation. Inhibition of ergosterol, protein and nucleic acid biosynthesis altered titan cell formation, as did serum, phospholipids and anti-capsular antibodies in our settings. We explored genetic factors important for titan cell formation using three approaches. Using H99-derivative strains with natural genetic differences, we showed that titan cell formation was dependent on LMP1 and SGF29 genes. By screening a gene deletion collection, we also confirmed that GPR4/5-RIM101, and CAC1 genes were required to generate titan cells and that the PKR1, TSP2, USV101 genes negatively regulated titan cell formation. Furthermore, analysis of spontaneous Pkr1 loss-of-function clinical isolates confirmed the important role of the Pkr1 protein as a negative regulator of titan cell formation. Through development of a standardized and robust in vitro assay, our results provide new insights into titan cell biogenesis with the identification of multiple important factors/pathways.nnAuthor SummaryCryptococcus neoformans is a yeast that is capable of morphological change upon interaction with the host. Particularly, in the lungs of infected mice, a subpopulation of yeast enlarges, producing cells up to 100 {micro}m in cell body diameter - referred to as titan cells. Along with their large size, the titan cells have other unique characteristics such as thickened cell wall, dense capsule, polyploidization, large vacuole with peripheral nucleus and cellular organelles. The generation of a large number of such cells outside the lungs of mice has been described but was not reproducible nor standardized. Here we report standardized, reproducible, robust conditions for generation of titan cells and explored the environmental and genetic factors underlying the genesis of these cells. We showed that titan cells were generated upon stresses such as change in the incubation medium, nutrient deprivation, hypoxia and low pH. Using collections of well characterized reference strains and clinical isolates, we validated with our model that the cAMP/PKA/Rim101 pathway is a major genetic determinant of titan cell formation. This study opens the way for a more comprehensive picture of the ontology of morphological changes in Cryptococcus neoformans and its impact on pathobiology of this deadly pathogen.
]]>Hommel, B.Mukaremera, L.Cordero, R. J. B.Desjardins, C. A.Sturny-Leclere, A.Perfect, J.Fraser, J. A.Casadevall, A.Cuomo, C. A.Dromer, F.Nielsen, K.Alanio, A.2017-09-20doi:10.1101/191668Cold Spring Harbor Laboratory Press2017-09-20
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SHAMAN: a user-friendly website for metataxonomic analysis from raw reads to statistical analysis
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https://biorxiv.org/cgi/content/short/2019.12.18.880773v1?rss=1"
Volant, S.Lechat, P.Woringer, P.Motreff, L.Malabat, C.Kennedy, S.Ghozlane, A.2019-12-19doi:10.1101/2019.12.18.880773Cold Spring Harbor Laboratory Press2019-12-19
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Optimal maturation of the SIV-specific CD8+ T-cell response after primary infection is associated with natural control of SIV. ANRS SIC study
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https://biorxiv.org/cgi/content/short/2019.12.20.885459v1?rss=1"
Passaes, C.Millet, A.Madelain, V.Monceaux, V.David, A.Versmisse, P.Sylla, N.Gostick, E.Price, D. A.Blancher, A.Bosquet, N.Pancino, G.Le Grand, R.Lambotte, O.Muller-Trutwin, M.Rouzioux, C.Guedj, J.Avettand-Fenoel, V.Vaslin, B.Saez-Cirion, A.2019-12-21doi:10.1101/2019.12.20.885459Cold Spring Harbor Laboratory Press2019-12-21
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A genome-wide Approximate Bayesian Computation approach suggests only limited numbers of soft sweeps in humans over the last 100,000 years
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https://biorxiv.org/cgi/content/short/2019.12.22.886234v1?rss=1"
Laval, G.Patin, E.Boutillier, P.Quintana-Murci, L.2019-12-23doi:10.1101/2019.12.22.886234Cold Spring Harbor Laboratory Press2019-12-23
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Automatic building of protein atomic models from cryo-EM density maps using residue co-evolution
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https://biorxiv.org/cgi/content/short/2020.01.03.893669v1?rss=1"
Bouvier, G.Bardiaux, B.Pellarin, R.Rapisarda, C.Nilges, M.2020-01-03doi:10.1101/2020.01.03.893669Cold Spring Harbor Laboratory Press2020-01-03
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Local retinoic acid directs emergence of the extraocular muscle functional unit
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https://biorxiv.org/cgi/content/short/2020.01.07.897694v1?rss=1"
Comai, G. E.Tesarova, M.Dupe, V.Rhinn, M.Vallecillo Garcia, P.da Silva, F.Feret, B.Exelby, K.Dolle, P.Carlsson, L.Pryce, B.Spitz, F.Stricker, S.Zikmund, T.Kaiser, J.Briscoe, J.Schedl, A.Ghyselinck, N. B.Schweitzer, R.Tajbakhsh, S.2020-01-07doi:10.1101/2020.01.07.897694Cold Spring Harbor Laboratory Press2020-01-07
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Streptococcus pneumoniae infection promotes histone H3 dephosphorylation by modulating host PP1 phosphatase
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https://biorxiv.org/cgi/content/short/2020.01.14.905968v1?rss=1"
Dong, W.Rasid, O.Chevalier, C.Connor, M.Eldridge, M.Hamon, M. A.2020-01-14doi:10.1101/2020.01.14.905968Cold Spring Harbor Laboratory Press2020-01-14
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New virus isolates from Italian hydrothermal environments underscore the biogeographic pattern in archaeal virus communities
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https://biorxiv.org/cgi/content/short/2020.01.16.907410v1?rss=1"
Baquero, D. P.Contursi, P.Piochi, M.Bartolucci, S.Liu, Y.Cvirkaite-Krupovic, V.Prangishvili, D.Krupovic, M.2020-01-17doi:10.1101/2020.01.16.907410Cold Spring Harbor Laboratory Press2020-01-17
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Phosphorylation Dependent Assembly of a 14-3-3 Mediated Signaling Complex During Red Blood Cell Invasion by Plasmodium falciparum Merozoites
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https://biorxiv.org/cgi/content/short/2020.01.17.911107v1?rss=1"
More, K. R.Kaur, I.Giai Gianetto, Q.Invergo, B. M.Chaze, T.Jain, R.Huon, C.Gutenbrunner, P.Weisser, H.Matondo, M.Chaudhary, J. S.Langsley, G.Singh, S.Chitnis, C. E.2020-01-20doi:10.1101/2020.01.17.911107Cold Spring Harbor Laboratory Press2020-01-20
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Remodeling of the core leads HIV-1 pre-integration complex in the nucleus of human lymphocytes.
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https://biorxiv.org/cgi/content/short/2020.01.24.918383v1?rss=1"
Blanco, G.Gazi, A.Monel, B.Frabetti, S.Scoca, V.Mueller, F.Schwartz, O.krijnse-locker, J.Charneau, P.Di Nunzio, F.2020-01-25doi:10.1101/2020.01.24.918383Cold Spring Harbor Laboratory Press2020-01-25
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Anopheles gambiae maternal age and parous state control offspring susceptibility to Plasmodium falciparum
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https://biorxiv.org/cgi/content/short/2020.01.27.922070v1?rss=1"
Mitri, C.Isabelle, T.Lecoq, M.-T.Thouvenot, C.Touron, S.Landier, A.Bischoff, E.Bourgouin, C.2020-01-28doi:10.1101/2020.01.27.922070Cold Spring Harbor Laboratory Press2020-01-28
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Population variation of miRNAs and isomiRs and their impact on human immunity to infection
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https://biorxiv.org/cgi/content/short/2020.01.31.928580v1?rss=1"
Rotival, M.Siddle, K. J.Silvert, M.Pothlichet, J.Quach, H.Quintana-Murci, L.2020-01-31doi:10.1101/2020.01.31.928580Cold Spring Harbor Laboratory Press2020-01-31
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Argonaute catalytic activity is required for maternal mRNA clearance in embryos
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https://biorxiv.org/cgi/content/short/2020.02.03.919597v1?rss=1"
Quarato, P.Singh, M.Cornes, E.Li, B.Bourdon, L.Cecere, G.2020-02-03doi:10.1101/2020.02.03.919597Cold Spring Harbor Laboratory Press2020-02-03
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Dynamic High-Content Imaging Reveals Surface Exposure Of Virulent Leishmania Amastigotes In Infected Macrophages Undergoing Pyroptosis
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https://biorxiv.org/cgi/content/short/2020.02.03.931907v1?rss=1"
Rosazza, T.Lecoeur, H.Blisnick, T.Moya-Nilges, M.Pescher, P.Bastin, P.Prina, E.Spaeth, G. F.2020-02-03doi:10.1101/2020.02.03.931907Cold Spring Harbor Laboratory Press2020-02-03
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RIG-I and PKR, but not stress granules, mediate the pro-inflammatory response to Yellow fever virus
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https://biorxiv.org/cgi/content/short/2020.02.05.935486v1?rss=1"
Beauclair, G.Streicher, F.Bruni, D.Bourgeau, S.Gracias, S.Sinigaglia, L.Fujita, T.Meurs, E. F.Tangy, F.jouvenet, n.2020-02-05doi:10.1101/2020.02.05.935486Cold Spring Harbor Laboratory Press2020-02-05
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Yolk sac erythromyeloid progenitors sustain erythropoiesis throughout embryonic life
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https://biorxiv.org/cgi/content/short/2020.02.27.968230v1?rss=1"
Soares-da-Silva, F.Burlen-Defranoux, O.Elsaid, R.Iturri, L.Freyer, L.Sismeiro, O.Pinto-do-O, P.Gomez-Perdiguero, E.Cumano, A.2020-03-01doi:10.1101/2020.02.27.968230Cold Spring Harbor Laboratory Press2020-03-01
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The low complexity regions in the C-terminus are essential for the subcellular localisation of Leishmania casein kinase 1 but not for its activity
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https://biorxiv.org/cgi/content/short/2020.02.28.969741v1?rss=1"
Martel, D.Pine, S.Bartsch, K.Clos, J.Spaeth, G. F.RACHIDI, N.2020-02-28doi:10.1101/2020.02.28.969741Cold Spring Harbor Laboratory Press2020-02-28
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The immune system fails to mount a protective response to Gram-positive or Gram-negative bacterial prostatitis
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https://biorxiv.org/cgi/content/short/2020.02.29.971051v1?rss=1"
Lupo, F.Rousseau, M.Canton, T.Ingersoll, M. A.2020-03-03doi:10.1101/2020.02.29.971051Cold Spring Harbor Laboratory Press2020-03-03
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RAD50 promotes DNA repair by homologous recombination and restrains antigenic variation in African trypanosomes
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https://biorxiv.org/cgi/content/short/2020.03.17.994905v1?rss=1"
Glover, L.Mehnert, A.-K.Hutchinson, S.McCulloch, R.2020-03-17doi:10.1101/2020.03.17.994905Cold Spring Harbor Laboratory Press2020-03-17
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Capsular polysaccharides cross-regulation modulates Bacteroides thetaiotaomicron biofilm formation
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https://biorxiv.org/cgi/content/short/2020.03.25.005728v1?rss=1"
BECHON, N.MIHAJLOVIC, J.VENDRELL-FERNANDEZ, S.CHAIN, F.LANGELLA, P.BELOIN, C.GHIGO, J.-M.2020-03-25doi:10.1101/2020.03.25.005728Cold Spring Harbor Laboratory Press2020-03-25
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The adaptive transcriptional response of pathogenic Leptospira to peroxide reveals new defenses against infection-related oxidative stress
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https://biorxiv.org/cgi/content/short/2020.04.03.015982v1?rss=1"
Zavala-Alvarado, C.Sismeiro, O.Legendre, R.Varet, H.Bussotti, G.Bayram, J.Garcia Huete, S.Rey, G.Coppee, J. Y.Picardeau, M.Benaroudj, N.2020-04-04doi:10.1101/2020.04.03.015982Cold Spring Harbor Laboratory Press2020-04-04
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Anti-apoptotic clone 11 derived peptides induce in vitro death of CD4+ T cells susceptible to HIV-1 infection
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https://biorxiv.org/cgi/content/short/2020.04.06.028860v1?rss=1"
Mikhailova, A.Valle-Casuso, J. C.David, A.Monceaux, V.Volant, S.Pereira-Bittencourt Passaes, C.Elfidha, A.Muller-Trutwin, M.Poyet, J. L.Saez-Cirion, A.2020-04-08doi:10.1101/2020.04.06.028860Cold Spring Harbor Laboratory Press2020-04-08
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Absence of SARS-CoV-2 infection in cats and dogs in close contact with a cluster of COVID-19 patients in a veterinary campus
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https://biorxiv.org/cgi/content/short/2020.04.07.029090v1?rss=1"
Temmam, S.Barbarino, A.Maso, D.Behillil, S.Enouf, V.Huon, C.Jaraud, A.Chevallier, L.Backovic, M.Perot, P.Verwaerde, P.Tiret, L.van der Werf, S.Eloit, M.2020-04-09doi:10.1101/2020.04.07.029090Cold Spring Harbor Laboratory Press2020-04-09
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Generating functional protein variants with variational autoencoders
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https://biorxiv.org/cgi/content/short/2020.04.07.029264v1?rss=1"
Hawkins-Hooker, A.Depardieu, F.Baur, S.Couairon, G.Chen, A.Bikard, D.2020-04-07doi:10.1101/2020.04.07.029264Cold Spring Harbor Laboratory Press2020-04-07
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Clustering and reverse transcription of HIV-1 genomes in nuclear niches of macrophages
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https://biorxiv.org/cgi/content/short/2020.04.12.038067v1?rss=1"
Rensen, E.Mueller, F.Scoca, V.Parmar, J.Souque, P.Zimmer, C.Di Nunzio, F.2020-04-13doi:10.1101/2020.04.12.038067Cold Spring Harbor Laboratory Press2020-04-13
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Functionally distinct resident macrophage subsets differentially shape responses to infection in the bladder
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https://biorxiv.org/cgi/content/short/2020.04.18.048074v1?rss=1"
Lacerda Mariano, L.Rousseau, M.Varet, H.Legendre, R.Gentek, R.Saenz Coronilla, J.Bajenoff, M.Gomez-Perdiguero, E.Ingersoll, M. A.2020-04-18doi:10.1101/2020.04.18.048074Cold Spring Harbor Laboratory Press2020-04-18
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Mining zebrafish microbiota reveals key community-level resistance against fish pathogen infection
]]>
https://biorxiv.org/cgi/content/short/2020.04.23.058222v1?rss=1"
GHIGO, J.-M.STRESSMANN, F. A.BERNAL-BAYARD, J.PEREZ-PASCUAL, D.AUDRAIN, B.RENDUELES, O.BRIOLAT, V.BRUCHMANN, S.VOLANT, S.GHOZLANE, A.HAUSSLER, S.DUCHAUD, E.LEVRAUD, J.-P.2020-04-24doi:10.1101/2020.04.23.058222Cold Spring Harbor Laboratory Press2020-04-24
<![CDATA[
Introductions and early spread of SARS-CoV-2 in France
]]>
https://biorxiv.org/cgi/content/short/2020.04.24.059576v1?rss=1"
Gambaro, F.Baidaliuk, A.Behillil, S.Donati, F.Albert, M.Alexandru, A.Vanpeene, M.Bizard, M.Brisebarre, A.Barbet, M.Derrar, F.van der Werf, S.Enouf, V.Simon-Loriere, E.2020-04-24doi:10.1101/2020.04.24.059576Cold Spring Harbor Laboratory Press2020-04-24
<![CDATA[
Proteomic Analysis Uncovers Measles Virus Protein C Interaction with p65/iASPP/p53 Protein Complex
]]>
https://biorxiv.org/cgi/content/short/2020.05.08.084418v1?rss=1"
Meignie, A.Combredet, C.Santolini, M.Kovacs, I. A.Douche, T.Giai Gianetto, Q.Eun, H.Matondo, M.Jacob, Y.Grailhe, R.Tangy, F.Komarova, A. V.2020-05-09doi:10.1101/2020.05.08.084418Cold Spring Harbor Laboratory Press2020-05-09
<![CDATA[
Visualizing the dynamics of exported bacterial proteins with the chemogenetic fluorescent reporter FAST
]]>
https://biorxiv.org/cgi/content/short/2020.05.12.090142v1?rss=1"
Chekli, Y.Peron-Cane, C.Dell'Arciprete, D.Allemand, J.-F.Li, C.GHIGO, J.-M.Gautier, A.Lebreton, A.Desprat, N.BELOIN, C.2020-05-13doi:10.1101/2020.05.12.090142Cold Spring Harbor Laboratory Press2020-05-13
<![CDATA[
Leptospiral LPS escapes mouse TLR4 internalization and TRIF?associated antimicrobial responses through O antigen and associated lipoproteins
]]>
https://biorxiv.org/cgi/content/short/2020.05.18.101857v1?rss=1"
Bonhomme, D.Santecchia, I.Vernel-Pauillac, F.Caroff, M.Germon, P.Murray, G.Adler, B.Boneca, I. G.Werts, C.2020-05-18doi:10.1101/2020.05.18.101857Cold Spring Harbor Laboratory Press2020-05-18
<![CDATA[
Population genomics and antimicrobial resistance in Corynebacterium diphtheriae
]]>
https://biorxiv.org/cgi/content/short/2020.05.19.101030v1?rss=1"
8 agents), including to penicillin and macrolides. Homologous recombination was frequent (r/m = 5) and horizontal gene transfer contributed to the emergence of antimicrobial resistance in multiple sublineages. Genome-wide association mapping uncovered genetic factors of resistance, including an accessory penicillin-binding protein (PBP2m) located in diverse genomic contexts. Gene pbp2m is widespread in other Corynebacterium species and its expression in C. glutamicum demonstrated its effect against several beta-lactams. A novel 73-kb C. diphtheriae multi-resistance plasmid was discovered.
This work uncovers the dynamics of antimicrobial resistance in C. diphtheriae in the context of phylogenetic structure, biovar and diphtheria toxin production, and provides a blueprint to analyze re-emerging diphtheria.
]]>Hennart, M.Panunzi, L. G.Rodrigues, C.Gaday, Q.Baines, S. L.Barros-Pinkelnig, M.Carmi-Leroy, A.Dazas, M.Wehenkel, A.-M.Didelot, X.Toubiana, J.Badell, E.Brisse, S.2020-05-20doi:10.1101/2020.05.19.101030Cold Spring Harbor Laboratory Press2020-05-20
<![CDATA[
Transcriptome and epigenome diversity and plasticity of muscle stem cells following transplantation
]]>
https://biorxiv.org/cgi/content/short/2020.05.20.107219v1?rss=1"
Evano, B.Gill, D.Hernando-Herraez, I.Comai, G.Stubbs, T.Commere, P.-H.Reik, W.Tajbakhsh, S.2020-05-22doi:10.1101/2020.05.20.107219Cold Spring Harbor Laboratory Press2020-05-22
<![CDATA[
Imaging the mechanisms of anti-CD20 therapy in vivo uncovers spatiotemporal bottlenecks in antibody-dependent phagocytosis
]]>
https://biorxiv.org/cgi/content/short/2020.05.26.116806v1?rss=1"
Grandjean, C. L.Garcia, Z.Lemaitre, F.Breart, B.Bousso, P.2020-05-29doi:10.1101/2020.05.26.116806Cold Spring Harbor Laboratory Press2020-05-29
<![CDATA[
A peptide-level multiple imputation strategy accounting for the different natures of missing values in proteomics data
]]>
https://biorxiv.org/cgi/content/short/2020.05.29.122770v1?rss=1"
Giai Gianetto, Q.Wieczorek, S.Coute, Y.Burger, T.2020-05-30doi:10.1101/2020.05.29.122770Cold Spring Harbor Laboratory Press2020-05-30
<![CDATA[
Escape of TLR5 Recognition by Leptospira spp: A Rationale for Atypical Endoflagella
]]>
https://biorxiv.org/cgi/content/short/2020.05.30.121202v1?rss=1"
Holzapfel, M.Bonhomme, D.Cagliero, J.Vernel-Pauillac, F.Fanton d'Andon, M.Bortolussi, S.Fiette, L.Goarant, C.Wunder, E.Picardeau, M.Ko, A.Werling, D.Matsui, M.Gomberts Boneca, I.Werts, C.2020-05-31doi:10.1101/2020.05.30.121202Cold Spring Harbor Laboratory Press2020-05-31
<![CDATA[
Bacteriocin production in Streptococcus gallolyticus by a complex 4-component regulatory system with activator and anti-activator activities
]]>
https://biorxiv.org/cgi/content/short/2020.06.04.131722v1?rss=1"
Proutiere, A.Perichon, B.du Merle, L.Varet, H.Trieu-Cuot, P.Dramsi, S.2020-06-04doi:10.1101/2020.06.04.131722Cold Spring Harbor Laboratory Press2020-06-04
<![CDATA[
Secretion, maturation and activity of a quorum-sensing peptide (GSP) inducing bacteriocins transcription in Streptococcus gallolyticus
]]>
https://biorxiv.org/cgi/content/short/2020.06.04.133652v1?rss=1"
Harrington, A.Proutiere, A.Tal-Gan, Y.Dramsi, S.2020-06-04doi:10.1101/2020.06.04.133652Cold Spring Harbor Laboratory Press2020-06-04
<![CDATA[
SCHNAPPs - Single Cell sHiNy APPlication(s)
]]>
https://biorxiv.org/cgi/content/short/2020.06.07.127274v1?rss=1"
Jagla, B.Rouilly, V.Puceat, M.Hasan, M.2020-06-09doi:10.1101/2020.06.07.127274Cold Spring Harbor Laboratory Press2020-06-09
<![CDATA[
Gnotobiotic rainbow trout (Oncorhynchus mykiss) model reveals endogenous bacteria that protect against Flavobacterium columnare infection
]]>
https://biorxiv.org/cgi/content/short/2020.06.19.161471v1?rss=1"
PEREZ-PASCUAL, D.VENDRELL-FERNANDEZ, S.AUDRAIN, B.BERNAL-BAYARD, J.PATINO-NAVARRETE, R.PETIT, V.RIGAUDEAU, D.GHIGO, J.-M.2020-06-20doi:10.1101/2020.06.19.161471Cold Spring Harbor Laboratory Press2020-06-20
<![CDATA[
Identification of sex differences in tumor-specific T cell infiltration in bladder tumor-bearing mice treated with BCG immunotherapy
]]>
https://biorxiv.org/cgi/content/short/2020.06.19.161554v1?rss=1"
Rousseau, M.O'Brien, C. J. O.Antequera, E.Zdimerova, H.Cansever, D.Canton, T.Zychlinsky Scharff, A.Ingersoll, M. A.2020-06-20doi:10.1101/2020.06.19.161554Cold Spring Harbor Laboratory Press2020-06-20
<![CDATA[
An exon DNA element modulates heterochromatin spreading in the master regulator for sexual commitment in malaria parasites
]]>
https://biorxiv.org/cgi/content/short/2020.06.26.163105v1?rss=1"
Cordon-Obras, C.Barcons-Simon, A.Scheidig- Benatar, C.Claes, A.Sabatet, V.Loew, D.Scherf, A.2020-06-26doi:10.1101/2020.06.26.163105Cold Spring Harbor Laboratory Press2020-06-26
<![CDATA[
Multitrait genetic-phenotype associations to connect disease variants and biological mechanisms
]]>
https://biorxiv.org/cgi/content/short/2020.06.26.172999v1?rss=1"
Julienne, H.Laville, V.McCaw, Z. R.He, Z.Guillemot, V.Lasry, C.Ziyatdinov, A.Vaysse, A.Lechat, P.Menager, H.Le Goff, W.Dube, M.-P.Kraft, P.Ionita-Laza, I.Vilhjalmsson, B. J.Aschard, H.2020-06-28doi:10.1101/2020.06.26.172999Cold Spring Harbor Laboratory Press2020-06-28
<![CDATA[
Mutational analysis to explore long-range allosteric coupling and decoupling in a pentameric channel receptor
]]>
https://biorxiv.org/cgi/content/short/2020.07.03.173997v1?rss=1"
Lefebvre, S. N.Taly, A.Menny, A.Medjebeur, K.Corringer, P.-J.2020-07-04doi:10.1101/2020.07.03.173997Cold Spring Harbor Laboratory Press2020-07-04
<![CDATA[
Spontaneous social communication in laboratory mice - placing ultrasonic vocalizations in their behavioral context
]]>
https://biorxiv.org/cgi/content/short/2020.07.09.195362v1?rss=1"
Elodie EyFabrice de ChaumontThomas Bourgeron2020-07-09doi:10.1101/2020.07.09.195362Cold Spring Harbor Laboratory Press2020-07-09
<![CDATA[
Syncytia formation by SARS-CoV-2 infected cells
]]>
https://biorxiv.org/cgi/content/short/2020.07.14.202028v1?rss=1"
Buchrieser, J.Dufloo, J.Hubert, M.Monel, B.Planas, D.Rajah, M. M.Planchais, C.Porrot, F.Guivel-Benhassine, F.van der Werf, S.Casartelli, N.Mouquet, H.Bruel, T.Schwartz, O.2020-07-14doi:10.1101/2020.07.14.202028Cold Spring Harbor Laboratory Press2020-07-14
<![CDATA[
Experimental adaptation of dengue virus 1 to Aedes albopictus mosquitoes by in vivo selection
]]>
https://biorxiv.org/cgi/content/short/2020.07.16.206524v1?rss=1"
Bellone, R.Lequime, S.Jupille, H.Goertz, G.Aubry, F.Mousson, L.Piorkowski, G.Yen, P.-S.Gabiane, G.Vazeille, M.Pijlman, G.Sakuntabhai, A.de Lamballerie, X.Lambrechts, L.Failloux, A.-B.2020-07-17doi:10.1101/2020.07.16.206524Cold Spring Harbor Laboratory Press2020-07-17
<![CDATA[
Actinobacteria challenge the paradigm: a unique protein architecture for a well-known central metabolic complex
]]>
https://biorxiv.org/cgi/content/short/2020.07.24.212647v1?rss=1"
Bruch, E. M.Vilela, P.Lexa-Sapart, N.Yang, L.Raynal, B.Alzari, P. M.Bellinzoni, M.2020-07-24doi:10.1101/2020.07.24.212647Cold Spring Harbor Laboratory Press2020-07-24
<![CDATA[
New insights into Cryptococcus extracellular vesicles suggest a new structural model and an antifungal vaccine strategy
]]>
https://biorxiv.org/cgi/content/short/2020.08.17.253716v1?rss=1"
Rizzo, j.Wong, S. S. W.Gazi, A. D.Moyrand, F.Chaze, T.Commere, P.-H.Matondo, M.Novault, S.PEHAU-ARNAUDET, G.Reis, F.Vos, M.Alves, L. R.May, R. C.Nimrichter, L. H.Rodrigues, M. L.AIMANIANDA, V.Janbon, G.2020-08-17doi:10.1101/2020.08.17.253716Cold Spring Harbor Laboratory Press2020-08-17
<![CDATA[
High transmissibility and fetal pathogenicity of recent Zika virus strains from the African lineage
]]>
https://biorxiv.org/cgi/content/short/2020.09.01.277673v1?rss=1"
Aubry, F.Jacobs, S.Darmuzey, M.Lequime, S.Delang, L.Fontaine, A.Jupatanakul, N.Miot, E. F.Dabo, S.Manet, C.Montagutelli, X.Baidaliuk, A.Gambaro, F.Simon-Loriere, E.Gilsoul, M.Romero-Vivas, C. M.Cao-Lormeau, V.-M.Jarman, R. G.Diagne, C. T.Faye, O.Faye, O.Sall, A. A.Neyts, J.Nguyen, L.Kaptein, S. J. F.Lambrechts, L.2020-09-01doi:10.1101/2020.09.01.277673Cold Spring Harbor Laboratory Press2020-09-01
<![CDATA[
Application of an optimized annotation pipeline to the Cryptococcus deuterogattii genome reveals dynamic primary metabolic gene clusters and genomic impact of RNAi loss
]]>
https://biorxiv.org/cgi/content/short/2020.09.01.278374v1?rss=1"
Ferrareze, P. A. G.Maufrais, C.Silva Aroujo Streit, R.Priest, S. J.Cuomo, C. A.Heitman, J.Staats, C. C.Janbon, G.2020-09-01doi:10.1101/2020.09.01.278374Cold Spring Harbor Laboratory Press2020-09-01
<![CDATA[
Translation and codon usage regulate Argonaute slicer activity to trigger small RNA biogenesis
]]>
https://biorxiv.org/cgi/content/short/2020.09.04.282863v1?rss=1"
Singh, M.Cornes, E.Li, B.Quarato, P.Bourdon, L.Dingli, F.Loew, D.Procaccia, S.Cecere, G.2020-09-04doi:10.1101/2020.09.04.282863Cold Spring Harbor Laboratory Press2020-09-04
<![CDATA[
PanACoTA: A modular tool for massive microbial comparative genomics
]]>
https://biorxiv.org/cgi/content/short/2020.09.11.293472v1?rss=1"
PERRIN, A.ROCHA, E.2020-09-11doi:10.1101/2020.09.11.293472Cold Spring Harbor Laboratory Press2020-09-11
<![CDATA[
A high-affinity calmodulin-binding site in the CyaA toxin translocation domain is essential for invasion into eukaryotic cells
]]>
https://biorxiv.org/cgi/content/short/2020.09.14.296129v1?rss=1"
Voegele, A.Sadi, M.O'Brien, D. P.Gehan, P.Raoux-Barbot, D.Davi, M.Hoss, S.Brule, S.Raynal, B.Weber, P.Mechaly, A.Haouz, A.Rodriguez, N.Vachette, P.Durand, D.Brier, S.Ladant, D.Chenal, A.2020-09-14doi:10.1101/2020.09.14.296129Cold Spring Harbor Laboratory Press2020-09-14
<![CDATA[
Lifestyle-specific S-nitrosylation of protein cysteine thiols regulates Escherichia coli biofilm formation and resistance to oxidative stress
]]>
https://biorxiv.org/cgi/content/short/2020.09.29.318139v1?rss=1"
BARRAUD, N.LETOFFE, S.BELOIN, C.VINH, J.CHIAPPETTA, G.GHIGO, J.-M.2020-09-29doi:10.1101/2020.09.29.318139Cold Spring Harbor Laboratory Press2020-09-29
<![CDATA[
Investigation of RNA metabolism through large-scale genetic interaction profiling in yeast
]]>
https://biorxiv.org/cgi/content/short/2020.10.04.325191v1?rss=1"
Decourty, L.Malabat, C.Frachon, E.Jacquier, A.Saveanu, C.2020-10-04doi:10.1101/2020.10.04.325191Cold Spring Harbor Laboratory Press2020-10-04
<![CDATA[
SARS-CoV-2 infection damages airway motile cilia and impairs mucociliary clearance
]]>
https://biorxiv.org/cgi/content/short/2020.10.06.328369v1?rss=1"
Robinot, R.Hubert, M.Dias de Melo, G.Lazarini, F.Bruel, T.Smith, N.Levallois, S.Larrous, F.Fernandes, J.Gellenoncourt, S.Rigaud, S.Gorgette, O.Thouvenot, C.Trebeau, C.Dumenil, G.Mallet, A.Gobaa, S.Etournay, R.Lledo, P.-M.Lecuit, M.Bourhy, H.Duffy, D.Michel, V.Schwartz, O.Chakrabarti, L. A.2020-10-06doi:10.1101/2020.10.06.328369Cold Spring Harbor Laboratory Press2020-10-06
<![CDATA[
Human USP18 is regulated by miRNAs via the 3'UTR, a sequence duplicated in lincRNA genes residing in chr22q11.21
]]>
https://biorxiv.org/cgi/content/short/2020.10.07.328385v1?rss=1"
Rubino, E.Cruciani, M.Tchitchek, N.Le Tortorec, A.Rolland, A.Veli, O.Vallet, L.Gaggi, G.Michel, F.Dejucq-Rainsford, N.Pellegrini, S.2020-10-08doi:10.1101/2020.10.07.328385Cold Spring Harbor Laboratory Press2020-10-08
<![CDATA[
Acquisition of a type 3 secretion signal in an housekeeping enzyme shaped glycogen metabolism in Chlamydia
]]>
https://biorxiv.org/cgi/content/short/2020.10.11.335026v1?rss=1"
Triboulet, S.N'Gadjaga, M. D.Niragire, B.Köstlbacher, S.Horn, M.Subtil, A.2020-10-12doi:10.1101/2020.10.11.335026Cold Spring Harbor Laboratory Press2020-10-12
<![CDATA[
Klebsiella MALDI TypeR: a web-based tool for Klebsiella identification based on MALDI-TOF mass spectrometry
]]>
https://biorxiv.org/cgi/content/short/2020.10.13.337162v1?rss=1"
Bridel, S. M.Watts, S. C.Judd, L. M.Harshegyi, T.Passet, V.Rodrigues, C.Holt, K. E.Brisse, S.2020-10-13doi:10.1101/2020.10.13.337162Cold Spring Harbor Laboratory Press2020-10-13
<![CDATA[
Tolerogenic Dendritic Cells Shape a Transmissible Gut Microbiota that Protects from Metabolic Diseases
]]>
https://biorxiv.org/cgi/content/short/2020.10.22.350033v1?rss=1"
Lecuyer, E.Le Roy, T.Gestin, A.Lacombe, A.Philippe, C.Ponnaiah, M.Hure, J. B.Fradet, M.Chou, F.Boudebbouze, S.Huby, T.Gautier, E.Rhimi, M.Maguin, E.Kapel, N.Gerard, P.Venteclef, N.Garlatti, M.Chassaing, B.Lesnik, P.2020-10-23doi:10.1101/2020.10.22.350033Cold Spring Harbor Laboratory Press2020-10-23
<![CDATA[
Ser/Thr kinase-dependent phosphorylation of the peptidoglycan hydrolase CwlA controls its export and modulates cell division in Clostridioides difficile
]]>
https://biorxiv.org/cgi/content/short/2020.10.29.360313v1?rss=1"
Garcia-Garcia, T.Poncet, S.Cuenot, E.Douche, T.Giai Gianetto, Q.PELTIER, J.Courtin, P.Chapot-Chartier, M.-P.Matondo, M.Dupuy, B.Candela, T.Martin-Verstraete, I.2020-10-29doi:10.1101/2020.10.29.360313Cold Spring Harbor Laboratory Press2020-10-29
<![CDATA[
The oxidative stress response and virulence of pathogenic Leptospira are controlled by the interplay of two peroxide stress regulators
]]>
https://biorxiv.org/cgi/content/short/2020.11.06.371039v1?rss=1"
Zavala-Alvarado, C.Vincent, A. T.Sismeiro, O.Legendre, R.Varet, H.Bussotti, G.Lorioux, C.Coppee, J.-Y.Veyrier, F. J.Picardeau, M.Benaroudj, N.2020-11-06doi:10.1101/2020.11.06.371039Cold Spring Harbor Laboratory Press2020-11-06
<![CDATA[
Bacteria have numerous phage-plasmid families with conserved phage and variable plasmid gene repertoires.
]]>
https://biorxiv.org/cgi/content/short/2020.11.09.375378v1?rss=1"
Pfeifer, E.de Sousa, J. A.Touchon, M.Rocha, E. P.2020-11-09doi:10.1101/2020.11.09.375378Cold Spring Harbor Laboratory Press2020-11-09
<![CDATA[
Salmonella endorses a dormant state within human epithelial cells for persistent infection
]]>
https://biorxiv.org/cgi/content/short/2020.11.14.382689v1?rss=1"
Luk, C. H.Chang, Y.-y.Enninga, J.2020-11-15doi:10.1101/2020.11.14.382689Cold Spring Harbor Laboratory Press2020-11-15
<![CDATA[
Salmonella subverts autophagy balancing bacterial fate and cellular inflammation
]]>
https://biorxiv.org/cgi/content/short/2020.11.15.383372v1?rss=1"
Luk, C. H.Yu, W.Deriano, L.Enninga, J.2020-11-15doi:10.1101/2020.11.15.383372Cold Spring Harbor Laboratory Press2020-11-15
<![CDATA[
Direct tracking of single proviruses reveals HIV-1/LEDGF complexes excluded from virus-induced membraneless organelles
]]>
https://biorxiv.org/cgi/content/short/2020.11.17.385567v1?rss=1"
Scoca, V.Louveaux, M.Morin, R.Ershov, D.Tinevez, J.-Y.Di Nunzio, F.2020-11-17doi:10.1101/2020.11.17.385567Cold Spring Harbor Laboratory Press2020-11-17
<![CDATA[
Bacterial inhibition of CD8+ T-cells mediated cell death promotes neuroinvasion and within-host persistence
]]>
https://biorxiv.org/cgi/content/short/2020.11.20.384974v1?rss=1"
Maudet, C.Kheloufi, M.Levallois, S.Gaillard, J.Huang, L.Gaultier, C.Tsai, Y.-H.Disson, O.Lecuit, M.2020-11-20doi:10.1101/2020.11.20.384974Cold Spring Harbor Laboratory Press2020-11-20
<![CDATA[
Patient-derived Glioblastoma Stem cells transfer mitochondria through Tunneling Nanotubes in Tumor Organoids
]]>
https://biorxiv.org/cgi/content/short/2020.11.21.392597v1?rss=1"
ZURZOLO, C.PINTO, G.SAENZ DE SANTA MARIA, I.CHASTAGNER, P.Perthame, E.DELMAS, C.TOULAS, C.Moyal-Jonathan-Cohen, E.BROU, C.2020-11-22doi:10.1101/2020.11.21.392597Cold Spring Harbor Laboratory Press2020-11-22
<![CDATA[
Anti-COVID-19 efficacy of ivermectin in the golden hamster
]]>
https://biorxiv.org/cgi/content/short/2020.11.21.392639v1?rss=1"
de Melo, G. D.Lazarini, F.Larrous, F.Feige, L.Kergoat, L.Marchio, A.Pineau, P.Lecuit, M.Lledo, P.-M.Changeux, J.-P.Bourhy, H.2020-11-22doi:10.1101/2020.11.21.392639Cold Spring Harbor Laboratory Press2020-11-22
<![CDATA[
Cassette recruitment in the chromosomal Integron of Vibrio cholerae
]]>
https://biorxiv.org/cgi/content/short/2020.11.24.395434v1?rss=1"
Vit, C.Richard, E.Fournes, F.Whiteway, C.Eyer, X.Lapaillerie, D.Parissi, V.Mazel, D.Loot, C.2020-11-24doi:10.1101/2020.11.24.395434Cold Spring Harbor Laboratory Press2020-11-24
<![CDATA[
Anti-Leptospira immunoglobulin profiling in mice reveals strain specific IgG and persistent IgM responses associated with virulence and renal colonization
]]>
https://biorxiv.org/cgi/content/short/2020.11.26.399667v1?rss=1"
Vernel-Pauillac, F.Murray, G. L.Adler, B.Boneca, I. G.Werts, C.2020-11-26doi:10.1101/2020.11.26.399667Cold Spring Harbor Laboratory Press2020-11-26
<![CDATA[
Basal Expression of Interferon-Stimulated Genes Drives Population Differences in Monocyte Susceptibility to Influenza Infection
]]>
https://biorxiv.org/cgi/content/short/2020.12.07.414151v1?rss=1"
O'Neill, M.Quach, H.Pothlichet, J.Aquino, Y.Bisiaux, A.Zidane, N.Deschamps, M.Libri, V.Hasan, M.Zhang, S.-Y.Zhang, Q.Matuozzo, D.Cobat, A.Abel, L.Casanova, J.-L.Naffakh, N.Rotival, M.Quintana-Murci, L.2020-12-07doi:10.1101/2020.12.07.414151Cold Spring Harbor Laboratory Press2020-12-07
<![CDATA[
Redistribution of FLAgellar Member 8 during the trypanosome life cycle: consequences for cell fate prediction.
]]>
https://biorxiv.org/cgi/content/short/2020.12.17.423316v1?rss=1"
CALVO ALVAREZ, E.BONNEFOY, S.SALLES, A.BENSON, F. E.McKEAN, P. G.BASTIN, P.ROTUREAU, B.2020-12-18doi:10.1101/2020.12.17.423316Cold Spring Harbor Laboratory Press2020-12-18
<![CDATA[
Emergence and global spread of Listeria monocytogenes main clinical clonal complex
]]>
https://biorxiv.org/cgi/content/short/2020.12.18.423387v1?rss=1"
Moura, A.Lefrancq, N.Leclercq, A.Wirth, T.Borges, V.Gilpin, B.Dallman, T. J.Frey, J.Franz, E.Nielsen, E. M.Thomas, J.Pightling, A.Howden, B. P.Tarr, C. L.Gerner-Smidt, P.Cauchemez, S.Salje, H.Brisse, S.Lecuit, M.Listeria CC1 Study Group,2020-12-20doi:10.1101/2020.12.18.423387Cold Spring Harbor Laboratory Press2020-12-20
<![CDATA[
Variation in pyrethroid resistance phenotypes in Anopheles darlingi from residual malaria transmission area: warning on suspected resistance built-up in French Guiana.
]]>
https://biorxiv.org/cgi/content/short/2020.12.21.423491v1?rss=1"
Vezenegho, S.Carinci, R.Issaly, J.Nguyen, C.Gaborit, P.Ferraro, L.Lacour, G.Mosnier, E.Pommier de Santi, V.Epelboin, Y.Girod, R.Briolant, S.Dusfour, I.2020-12-21doi:10.1101/2020.12.21.423491Cold Spring Harbor Laboratory Press2020-12-21
<![CDATA[
Dynamics of myogenic differentiation using a novel Myogenin knock-in reporter mouse
]]>
https://biorxiv.org/cgi/content/short/2020.12.21.423736v1?rss=1"
Benavente-Diaz, M.Comai, G.Di Girolamo, D.Langa, F.Tajbakhsh, S.2020-12-21doi:10.1101/2020.12.21.423736Cold Spring Harbor Laboratory Press2020-12-21
<![CDATA[
Overlapping Definitive Progenitor Waves Divide and Conquer to Build a Layered Hematopoietic System
]]>
https://biorxiv.org/cgi/content/short/2020.12.24.424302v1?rss=1"
Freyer, L.Iturri, L.Biton, A.Gomez-Perdiguero, E.2020-12-24doi:10.1101/2020.12.24.424302Cold Spring Harbor Laboratory Press2020-12-24
<![CDATA[
Enhancing multi-bioreactor platforms for automated measurements and reactive experiment control
]]>
https://biorxiv.org/cgi/content/short/2020.12.27.424467v1?rss=1"
Bertaux, F.Sosa Carillo, S.Fraisse, A.Aditya, C.Furstenheim, M.Batt, G.2020-12-27doi:10.1101/2020.12.27.424467Cold Spring Harbor Laboratory Press2020-12-27
<![CDATA[
FLAgellum Member 8 modulates extravascular trypanosome distribution in the mammalian host
]]>
https://biorxiv.org/cgi/content/short/2021.01.08.425862v1?rss=1"
Calvo Alvarez, E.Crouzols, A.Rotureau, B.2021-01-08doi:10.1101/2021.01.08.425862Cold Spring Harbor Laboratory Press2021-01-08
<![CDATA[
DProj: A toolbox for local 2D projection and accurate morphometrics of large 3D microscopy images.
]]>
https://biorxiv.org/cgi/content/short/2021.01.15.426809v1?rss=1"
Herbert, S.Valon, L.Mancini, L.Dray, N.Caldarelli, P.Gros, J.Esposito, E.Shorte, S. L.Bally-Cuif, L.Levayer, R.Aulner, N.Tinevez, J.-Y.2021-01-17doi:10.1101/2021.01.15.426809Cold Spring Harbor Laboratory Press2021-01-17
<![CDATA[
The CovR regulatory network drives the evolution of Group B Streptococcus virulence
]]>
https://biorxiv.org/cgi/content/short/2021.01.25.428120v1?rss=1"
Mazzuoli, M. V.Daunesse, M.Varet, H.Rosinski-Chupin, I.Legendre, R.Sismeiro, O.Gominet, M.Kaminski, P. A.Glaser, P.Chica, C.Trieu-Cuot, P.Firon, A.2021-01-25doi:10.1101/2021.01.25.428120Cold Spring Harbor Laboratory Press2021-01-25
<![CDATA[
Age-associated gut microbiota impairs hippocampus-dependent memory in a vagus dependent manner
]]>
https://biorxiv.org/cgi/content/short/2021.01.28.428594v1?rss=1"
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]]>Rei, D.Saha, S.Haddad, M.Haider Rubio, A.Ungeheuer, M.-N.Sokol, H.Lledo, P.-M.2021-01-30doi:10.1101/2021.01.28.428594Cold Spring Harbor Laboratory Press2021-01-30
<![CDATA[
Host PDZ-containing proteins targeted by SARS-Cov-2
]]>
https://biorxiv.org/cgi/content/short/2021.02.01.429176v1?rss=1"
Caillet-Saguy, C.Durbesson, F.REZELJ, V. V.Gogl, G.Tran, Q. D.Twizere, J.-C.Vignuzzi, M.Vincentelli, R.Wolff, N.2021-02-01doi:10.1101/2021.02.01.429176Cold Spring Harbor Laboratory Press2021-02-01
<![CDATA[
ChIPuana: from raw data to epigenomic dynamics
]]>
https://biorxiv.org/cgi/content/short/2021.02.02.429342v1?rss=1"
Daunesse, M.Legendre, R.Varet, H.Pain, A.Chica, C.2021-02-02doi:10.1101/2021.02.02.429342Cold Spring Harbor Laboratory Press2021-02-02
<![CDATA[
Full Brain and Lung Prophylaxis against SARS-CoV-2 by Intranasal Lentiviral Vaccination in a New hACE2 Transgenic Mouse Model or Golden Hamsters
]]>
https://biorxiv.org/cgi/content/short/2021.02.03.429211v1?rss=1"
Ku, M.-W.Authie, P.Bourgine, M.Anna, F.Noirat, A.Moncoq, F.Vesin, B.Nevo, F.Lopez, J.Souque, P.Blanc, C.Chardenoux, S.Lafosse, I.Hardy, D.Nemirov, K.Guinet, F.Langa Vives, F.Majlessi, L.Charneau, P.2021-02-03doi:10.1101/2021.02.03.429211Cold Spring Harbor Laboratory Press2021-02-03
<![CDATA[
Sensitive visualization of SARS-CoV-2 RNA with CoronaFISH
]]>
https://biorxiv.org/cgi/content/short/2021.02.04.429604v1?rss=1"
Rensen, E. I.Pietropaoli, S.Weber, C.Souquere, S.Isnard, P.Rabant, M.Gibier, J.-B.Simon-Loriere, E.Rameix-Welti, M.-A.Pierron, G.Mueller, F.Barba-Spaeth, G.Zimmer, C.2021-02-04doi:10.1101/2021.02.04.429604Cold Spring Harbor Laboratory Press2021-02-04
<![CDATA[
POPULATION GENOMIC ANALYSIS OF CRYPTOCOCCUS BRAZILIAN STRAINS REVEALS AN AFRICAN TYPE SUBCLADES DISTRIBUTION
]]>
https://biorxiv.org/cgi/content/short/2021.02.08.430197v1?rss=1"
Maufrais, C.de Oliveira, L.Bastos, R. W.Moyrand, F.Reis, F. C.Valero, C.Gimenez, B.Josefowicz, L. J.Goldman, G. H.Rodrigues, M. L.Janbon, G.2021-02-08doi:10.1101/2021.02.08.430197Cold Spring Harbor Laboratory Press2021-02-08
<![CDATA[
Archaeal extracellular vesicles are produced in an ESCRT-dependent manner and promote gene transfer and nutrient cycling in extreme environments
]]>
https://biorxiv.org/cgi/content/short/2021.02.09.430445v1?rss=1"
Liu, J.Cvirkaite-Krupovic, V.Commere, P.-H.Yang, Y.Zhou, F.Shen, Y.Forterre, P.Krupovic, M.2021-02-09doi:10.1101/2021.02.09.430445Cold Spring Harbor Laboratory Press2021-02-09
<![CDATA[
Sensitivity of infectious SARS-CoV-2 B.1.1.7 and B.1.351 variants to neutralizing antibodies
]]>
https://biorxiv.org/cgi/content/short/2021.02.12.430472v1?rss=1"
Planas, D.Bruel, T.Grzelak, L.Guivel-Benhassine, F.Staropoli, I.Porrot, F.Planchais, C.Buchrieser, J.Rajah, M. M.Bishop, E.Albert, M.Donati, F.Behillil, S.Enouf, V.Marianne, M.Gonzalez, M.De Seze, J.Pere, H.Veyer, D.Seve, A.Simon-Loriere, E.Fafi-Kremer, S.Stefic, K.Mouquet, H.Hocqueloux, L.van der Werf, S.Prazuck, T.Schwartz, O.2021-02-12doi:10.1101/2021.02.12.430472Cold Spring Harbor Laboratory Press2021-02-12
<![CDATA[
Cuban history of CRF19 recombinant subtype of HIV-1
]]>
https://biorxiv.org/cgi/content/short/2021.02.15.431210v1?rss=1"
ZHUKOVA, A.Voznica, J.Davila Felipe, M.To, T.-H.Perez, L.Martinez, Y.Pintos, Y.Mendez, M.Gascuel, O.Kouri, V.2021-02-16doi:10.1101/2021.02.15.431210Cold Spring Harbor Laboratory Press2021-02-16
<![CDATA[
A measles-vectored COVID-19 vaccine induces long-term immunity and protection from SARS-CoV-2 challenge in mice
]]>
https://biorxiv.org/cgi/content/short/2021.02.17.431630v1?rss=1"
Frantz, P. N.Barinov, A.Ruffie, C.Combredet, C.Najburg, V.Teeravechyan, S.Jongkaewwattana, A.Prot, M.Conquet, L.Montagutelli, X.Fernandes, P.Strick-Marchand, H.Di Santo, J.Simon-Loriere, E.Gerke, C.Tangy, F.2021-02-17doi:10.1101/2021.02.17.431630Cold Spring Harbor Laboratory Press2021-02-17
<![CDATA[
Automated strain separation in low-complexity metagenomes using long reads
]]>
https://biorxiv.org/cgi/content/short/2021.02.24.429166v1?rss=1"
Vicedomini, R.Quince, C.Darling, A. E.Chikhi, R.2021-02-25doi:10.1101/2021.02.24.429166Cold Spring Harbor Laboratory Press2021-02-25
<![CDATA[
A synaptic novelty signal in the dentate gyrus supports switching hippocampal attractor networks from generalization to discrimination
]]>
https://biorxiv.org/cgi/content/short/2021.02.24.432612v1?rss=1"
Gomez-Ocadiz, R.Trippa, M.Posani, L.Cocco, S.Monasson, R.Schmidt-Hieber, C.2021-02-25doi:10.1101/2021.02.24.432612Cold Spring Harbor Laboratory Press2021-02-25
<![CDATA[
Evolution of VIM-1 producing Klebsiella pneumoniae isolates from a hospital outbreak reveals the genetic bases of the loss of the urease-positive identification character
]]>
https://biorxiv.org/cgi/content/short/2021.03.02.433680v1?rss=1"
Cabanel, N.Rosinski-Chupin, I.Chiarelli, A.Botin, T.Tato, M.Canton, R.Glaser, P.2021-03-06doi:10.1101/2021.03.02.433680Cold Spring Harbor Laboratory Press2021-03-06
<![CDATA[
Differential levels of IFNα subtypes in autoimmunity and viral infection
]]>
https://biorxiv.org/cgi/content/short/2021.03.04.433900v1?rss=1"
Bondet, V.Rodero, M. P.Posseme, C.Bost, P.Decalf, J.Haljasmagi, L.Bekaddour, N.Rice, G.Upasani, V.Herbeuval, J.-P.Reynolds, J. A.Briggs, T. A.Bruce, I. N.Mauri, C.Isenberg, D.Menon, M.Hunt, D.Schwikowski, B.Mariette, X.Pol, S.Rozenberg, F.Cantaert, T.Gottenberg, J.-E.Kisand, K.Duffy, D.2021-03-05doi:10.1101/2021.03.04.433900Cold Spring Harbor Laboratory Press2021-03-05
<![CDATA[
Combination of in vivo phage therapy data with in silico model highlights key parameters for treatment efficacy
]]>
https://biorxiv.org/cgi/content/short/2021.03.04.433924v1?rss=1"
Delattre, R.Seurat, J.Haddad, F.Nguyen, T.-T.Gaborieau, B.Kane, R.Dufour, N.Ricard, J.-D.Guedj, J.Debarbieux, L.2021-03-04doi:10.1101/2021.03.04.433924Cold Spring Harbor Laboratory Press2021-03-04
<![CDATA[
The B1.351 and P.1 variants extend SARS-CoV-2 host range to mice
]]>
https://biorxiv.org/cgi/content/short/2021.03.18.436013v1?rss=1"
Montagutelli, X.Prot, M.Levillayer, L.Baquero Salazar, E.Jouvion, G.Conquet, L.Donati, F.Albert, M.Gambaro, F.Behillil, S.Enouf, V.Rousset, D.Jaubert, J.Rey, F.van der Werf, S.Simon-Loriere, E.2021-03-18doi:10.1101/2021.03.18.436013Cold Spring Harbor Laboratory Press2021-03-18
<![CDATA[
Post-transcriptional regulation of Leishmania fitness gain
]]>
https://biorxiv.org/cgi/content/short/2021.03.22.436378v1?rss=1"
Piel, L.Rajan, K. S.Bussotti, G.Varet, H.Legendre, R.Proux, C.Douche, T.Giai Gianetto, Q.Chaze, T.Vojtkova, B.Gordon-Bar, N.Doniger, T.Cohen-Chalamish, S.Rengaraj, P.Besse, C.Boland, A.Sadlova, J.Deleuze, J.-F.Matondo, M.Unger, R.Volf, P.Michaeli, S.Pescher, P.Spaeth, G. F.2021-03-22doi:10.1101/2021.03.22.436378Cold Spring Harbor Laboratory Press2021-03-22
<![CDATA[
Human herpesvirus 8 molecular mimicry of ephrin ligands facilitates cell entry and triggers EphA2 signaling
]]>
https://biorxiv.org/cgi/content/short/2021.03.26.437132v1?rss=1"
Light, T. L.Brun, D.Guardado-Calvo, P.Pederzoli, R.Haouz, A.Neipel, F.Rey, F. A.Hristova, K.Backovic, M.2021-03-28doi:10.1101/2021.03.26.437132Cold Spring Harbor Laboratory Press2021-03-28
<![CDATA[
To catch a hijacker: abundance, evolution and genetic diversity of P4-like bacteriophage satellites
]]>
https://biorxiv.org/cgi/content/short/2021.03.30.437493v1?rss=1"
Sousa, J. M. d.Rocha, E. P. C.2021-03-30doi:10.1101/2021.03.30.437493Cold Spring Harbor Laboratory Press2021-03-30
<![CDATA[
Regulation of DIM-2-dependent repeat-induced point mutation (RIP) by the recombination-independent homologous DNA pairing in Neurospora crassa
]]>
https://biorxiv.org/cgi/content/short/2021.04.05.438447v1?rss=1"
Carlier, F.Nguyen, T.-S.Mazur, A. K.Gladyshev, E.2021-04-06doi:10.1101/2021.04.05.438447Cold Spring Harbor Laboratory Press2021-04-06
<![CDATA[
Exploring zebrafish larvae as a COVID-19 model: probable SARS-COV-2 replication in the swim bladder
]]>
https://biorxiv.org/cgi/content/short/2021.04.08.439059v1?rss=1"
Laghi, V.Rezelj, V.Boucontet, L.Boudinot, P.Salinas, I.Lutfalla, G.Vignuzzi, M.Levraud, J.-P.2021-04-10doi:10.1101/2021.04.08.439059Cold Spring Harbor Laboratory Press2021-04-10
<![CDATA[
Computational and biochemical analysis of type IV Pilus dynamics and stability
]]>
https://biorxiv.org/cgi/content/short/2021.04.14.439816v1?rss=1"
Karami, Y.Lopez Castilla, A.Ori, A.Thomassin, J.-L.Bardiaux, B.Malliavin, T. E.Izadi-Pruneyre, N.Francetic, O.Nilges, M.2021-04-14doi:10.1101/2021.04.14.439816Cold Spring Harbor Laboratory Press2021-04-14
<![CDATA[
Characterization of a triad of genes in cyanophage S-2L sufficient to replace adenine by 2-aminoadenine in bacterial DNA
]]>
https://biorxiv.org/cgi/content/short/2021.04.30.442174v1?rss=1"
Czernecki, D.Bonhomme, F.Kaminski, P.-A.Delarue, M.2021-04-30doi:10.1101/2021.04.30.442174Cold Spring Harbor Laboratory Press2021-04-30
<![CDATA[
The dengue virus NS1 protein conveys pro-inflammatory signals by docking onto human high-density lipoproteins
]]>
https://biorxiv.org/cgi/content/short/2021.05.05.442454v1?rss=1"
Benfrid, S.Park, K.-H. P.Dellarole, M.Voss, J. E.Tamietti, C.Pehau-Arnaudet, G.Raynal, B.Brule, S.England, P.Zhang, X.Mikhailova, A.Ungeheuer, M.-N.Petres, S.Biering, S.Harris, E.Sakuntabhai, A.Buchy, P.Duong, V.Dussart, P.Coulibaly, F.Bontems, F.Rey, F. A.Flamand, M.2021-05-05doi:10.1101/2021.05.05.442454Cold Spring Harbor Laboratory Press2021-05-05
<![CDATA[
SILAKin: A novel high throughput SILAC and mass spectrometry-based assay to identify the substratome of kinases secreted by pathogens
]]>
https://biorxiv.org/cgi/content/short/2021.05.05.442720v1?rss=1"
Smirlis, D.Dingli, F.Sabatet, V.Roth, A.Knippchild, U.Loew, D.Spaeth, G. F.Rachidi, N.2021-05-05doi:10.1101/2021.05.05.442720Cold Spring Harbor Laboratory Press2021-05-05
<![CDATA[
Reverting the mode of action of the mitochondrial FOF1-ATPase by Legionella pneumophila preserves its replication niche
]]>
https://biorxiv.org/cgi/content/short/2021.05.12.443790v1?rss=1"
Escoll, P.Platon, L.Drame, M.Sahr, T.Schmidt, S.Rusniok, C.Buchrieser, C.2021-05-14doi:10.1101/2021.05.12.443790Cold Spring Harbor Laboratory Press2021-05-14
<![CDATA[
Mosquito-bacteria interactions during larval development trigger metabolic changes with carry-over effects on adult fitness
]]>
https://biorxiv.org/cgi/content/short/2021.05.20.444942v1?rss=1"
Giraud, E.Varet, H.Legendre, R.Sismeiro, O.Aubry, F.Dabo, S.Dickson, L. B.Valiente Moro, C.LAMBRECHTS, L.2021-05-20doi:10.1101/2021.05.20.444942Cold Spring Harbor Laboratory Press2021-05-20
<![CDATA[
The impact of resource provisioning on the epidemiological responses of different parasites
]]>
https://biorxiv.org/cgi/content/short/2021.05.22.445253v1?rss=1"
Erazo, D.Pedersen, A. B.Fenton, A.2021-05-23doi:10.1101/2021.05.22.445253Cold Spring Harbor Laboratory Press2021-05-23
<![CDATA[
Epigenomic signature of the progeroid Cockayne syndrome exposes distinct and common features with physiological ageing
]]>
https://biorxiv.org/cgi/content/short/2021.05.23.445308v1?rss=1"
Crochemore, C.Chica, C.Garagnani, P.Lattanzi, G.Horvath, S.Sarasin, A.Franceschi, C.Bacalini, M. G.Ricchetti, M.2021-05-24doi:10.1101/2021.05.23.445308Cold Spring Harbor Laboratory Press2021-05-24
<![CDATA[
Identification of bipotent progenitors that give rise to myogenic and connective tissues in mouse
]]>
https://biorxiv.org/cgi/content/short/2021.05.26.445757v1?rss=1"
Grimaldi, A.Comai, G. E.Mella, S.Tajbakhsh, S.2021-05-26doi:10.1101/2021.05.26.445757Cold Spring Harbor Laboratory Press2021-05-26
<![CDATA[
Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individuals
]]>
https://biorxiv.org/cgi/content/short/2021.05.26.445838v1?rss=1"
Planas, D.Veyer, D.Baidaliuk, A.Staropoli, I.Guivel-Benhassine, F.Rajah, M.Planchais, C.Porrot, F.Robillard, N.Puech, J.Prot, M.Gallais, F.Gantner, P.Velay, A.Le Guen, J.Kassis-Chikhani, N.Edriss, D.Belec, L.Seve, A.Pere, H.Courtellemenont, L.Hocqueloux, L.Fafi-Kremer, S.Prazuck, T.Mouquet, H.Bruel, T.Simon-Loriere, E.Rey, F.Schwartz, O.2021-05-27doi:10.1101/2021.05.26.445838Cold Spring Harbor Laboratory Press2021-05-27
<![CDATA[
Differential transcriptomic response of Anopheles arabiensis to Plasmodium vivax and Plasmodium falciparum infection
]]>
https://biorxiv.org/cgi/content/short/2021.05.28.446219v1?rss=1"
Tchioffo Tsapi, M.Kornobis, E.Puchot, N.English, S.Proux, C.Goupeyou-Youmsi, J.Sakuntabhai, A.Dillies, M.-A.Randrianarivelojosia, M.Girod, R.Ndiath, M. o.Bourgouin, C.2021-05-28doi:10.1101/2021.05.28.446219Cold Spring Harbor Laboratory Press2021-05-28
<![CDATA[
Species-specific molecular barriers to SARS-CoV-2 replication in bat cells
]]>
https://biorxiv.org/cgi/content/short/2021.05.31.446374v1?rss=1"
Aicher, S.-M.Streicher, F.Chazal, M.Planas, D.Luo, D.Buchrieser, J.Nemcova, M.Seidlova, V.Zukal, J.Serra-Cobo, J.Pontier, D.Schwartz, O.Pikula, J.Dacheux, L.Jouvenet, N.2021-05-31doi:10.1101/2021.05.31.446374Cold Spring Harbor Laboratory Press2021-05-31
<![CDATA[
Reverse-Complement Equivariant Networks for DNA Sequences
]]>
https://biorxiv.org/cgi/content/short/2021.06.03.446953v1?rss=1"
Mallet, V.Vert, J.-P.2021-06-03doi:10.1101/2021.06.03.446953Cold Spring Harbor Laboratory Press2021-06-03
<![CDATA[
Minimizer-space de Bruijn graphs
]]>
https://biorxiv.org/cgi/content/short/2021.06.09.447586v1?rss=1"
Ekim, B.Berger, B.Chikhi, R.2021-06-10doi:10.1101/2021.06.09.447586Cold Spring Harbor Laboratory Press2021-06-10
<![CDATA[
Gotree/Goalign : Toolkit and Go API to facilitate the development of phylogenetic workflows
]]>
https://biorxiv.org/cgi/content/short/2021.06.09.447704v1?rss=1"
Lemoine, F.Gascuel, O.2021-06-10doi:10.1101/2021.06.09.447704Cold Spring Harbor Laboratory Press2021-06-10
<![CDATA[
B.1.1.7 and B.1.351 SARS-CoV-2 variants display enhanced Spike-mediated fusion
]]>
https://biorxiv.org/cgi/content/short/2021.06.11.448011v1?rss=1"
Rajah, M. M.Hubert, M.Bishop, E.Saunders, N.Robinot, R.Grzelak, L.Planas, D.Zivaljic, M.Planchais, C.Guivel-Benhassine, F.Porrot, F.Mouquet, H.Chakrabarti, L.Buchrieser, J.Schwartz, O.2021-06-11doi:10.1101/2021.06.11.448011Cold Spring Harbor Laboratory Press2021-06-11
<![CDATA[
A TPR scaffold couples signal detection to OdhI phosphorylation in metabolic control by the protein kinase PknG
]]>
https://biorxiv.org/cgi/content/short/2021.06.11.448168v1?rss=1"
Lisa, M. N.Sogues, A.Barilone, N.Baumgart, M.Gil, M.Grana, M.Duran, R.Biondi, R. M.Bellinzoni, M.Bott, M.Alzari, P. M.2021-06-13doi:10.1101/2021.06.11.448168Cold Spring Harbor Laboratory Press2021-06-13
<![CDATA[
Genome instability drives epistatic adaptation in the human pathogen Leishmania
]]>
https://biorxiv.org/cgi/content/short/2021.06.15.448517v1?rss=1"
Bussotti, G.Piel, L.Pescher, P.Domagalska, M. A.Rajan, K. S.Doniger, T.Hiregange, D. G.Myler, P. J.Unger, R.Michaeli, S. J.Spaeth, G. F.2021-06-15doi:10.1101/2021.06.15.448517Cold Spring Harbor Laboratory Press2021-06-15
<![CDATA[
GIP: An open-source computational pipeline for mapping genomic instability from protists to cancer cells
]]>
https://biorxiv.org/cgi/content/short/2021.06.15.448580v1?rss=1"
Spaeth, G. F.Bussotti, G.2021-06-16doi:10.1101/2021.06.15.448580Cold Spring Harbor Laboratory Press2021-06-16
<![CDATA[
Candida albicans Isolates 529L and CHN1 Exhibit Stable Colonization of the Murine Gastrointestinal Tract
]]>
https://biorxiv.org/cgi/content/short/2021.06.27.450080v1?rss=1"
McDonough, L.Mishra, A. A.Tosini, N.Kakade, P.Penumutchu, S.Liang, S.-H.Maufrais, C.Zhai, B.Taur, Y.Belenky, P.Bennett, R. J.Hohl, T. J.Koh, A. Y.Ene, I. V.2021-06-27doi:10.1101/2021.06.27.450080Cold Spring Harbor Laboratory Press2021-06-27
<![CDATA[
Single-cell analyses of immune thrombocytopenic patients reveal multiorgan dissemination of high-affinity autoreactive plasma cells
]]>
https://biorxiv.org/cgi/content/short/2021.06.29.450355v1?rss=1"
3,300 single IgG-SC from spleen, bone marrow and/or blood of 27 patients with ITP revealing high inter-individual variability in affinity for GPIIbIIIa with variations over 3 logs. IgG-SC dissemination and range of affinities were however similar per patient. Longitudinal analysis of autoreactive IgG-SC upon treatment with anti-CD38 mAb daratumumab demonstrated variable outcomes, from complete remission to failure with persistence of high-affinity anti-GPIIbIIIa IgG-SC in the bone marrow. This study demonstrates the existence and dissemination of high-affinity autoreactive plasma cells in multiple anatomical compartments of patients with ITP that may cause the failure of current therapies.
]]>Canales Herrerias, P.Crickx, E.Broketa, M.Sokal, A.Chenon, G.Azzaoui, I.Vandenberghe, A.Perima, A.Iannascoli, B.Richard-Le Goff, O.Castrillon, C.Mottet, G.Sterlin, D.Robbins, A.Michel, M.England, P.Millot, G. A.Eyer, K.Baudry, J.Mahevas, M.Bruhns, P.2021-06-30doi:10.1101/2021.06.29.450355Cold Spring Harbor Laboratory Press2021-06-30
<![CDATA[
Genomic evolution of the globally disseminated multidrug-resistant Klebsiella pneumoniae clonal group 147
]]>
https://biorxiv.org/cgi/content/short/2021.07.03.450759v1?rss=1"
Rodrigues, C.Desai, S.Passet, V.Gajjar, D.Brisse, S.2021-07-03doi:10.1101/2021.07.03.450759Cold Spring Harbor Laboratory Press2021-07-03
<![CDATA[
Inhibitory control of synaptic signals preceding motor action in mouse frontal cortex
]]>
https://biorxiv.org/cgi/content/short/2021.07.05.451151v1?rss=1"
Zhang, C.Koukouli, F.Allegra, M.Ortiz, C.Kao, H.-L.Maskos, U.Changeux, J.-P.Schmidt-Hieber, C.2021-07-06doi:10.1101/2021.07.05.451151Cold Spring Harbor Laboratory Press2021-07-06
<![CDATA[
De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
]]>
https://biorxiv.org/cgi/content/short/2021.07.08.451715v1?rss=1"
Laval, T.Pedro-Cos, L.Malaga, W.Guenin-Mace, L.Pawlik, A.Mayau, V.Yahia-Cherbal, H.Frigui, W.Bertrand-Michel, J.Guilhot, C.Demangel, C.2021-07-10doi:10.1101/2021.07.08.451715Cold Spring Harbor Laboratory Press2021-07-10
<![CDATA[
A mouse-adapted SARS-CoV-2 strain replicating in standard laboratory mice.
]]>
https://biorxiv.org/cgi/content/short/2021.07.10.451880v1?rss=1"
Montagutelli, X.Prot, M.Jouvion, G.Levillayer, L.Conquet, L.Reyes-Gomez, E.Donati, F.Albert, M.van der Werf, S.Jaubert, J.Simon-Loriere, E.2021-07-10doi:10.1101/2021.07.10.451880Cold Spring Harbor Laboratory Press2021-07-10
<![CDATA[
DNA double strand break position leads to distinct gene expression changes and regulates VSG switching pathway choice.
]]>
https://biorxiv.org/cgi/content/short/2021.07.15.452463v1?rss=1"
Thivolle, A.Mehnert, A.-K.Tihon, E.McLaughlin, E.Dujeancourt-Henry, A.Glover, L.2021-07-15doi:10.1101/2021.07.15.452463Cold Spring Harbor Laboratory Press2021-07-15
<![CDATA[
Innate immune pathways act synergistically to constrain RNA virus evolution in Drosophila melanogaster
]]>
https://biorxiv.org/cgi/content/short/2021.07.16.452470v1?rss=1"
Mongelli, V.Lequime, S.Kousathanas, A.Gausson, V.Blanc, H.Quintana-Murci, L.Elena, S. F.Saleh, M.-C.2021-07-16doi:10.1101/2021.07.16.452470Cold Spring Harbor Laboratory Press2021-07-16
<![CDATA[
Histone H3 deacetylation promotes host cell viability for efficient infection by Listeria monocytogenes
]]>
https://biorxiv.org/cgi/content/short/2021.07.16.452630v1?rss=1"
Eldridge, M. J. G.Hamon, M. A.2021-07-16doi:10.1101/2021.07.16.452630Cold Spring Harbor Laboratory Press2021-07-16
<![CDATA[
Genomic epidemiology and strain taxonomy of Corynebacterium diphtheriae
]]>
https://biorxiv.org/cgi/content/short/2021.07.18.452871v1?rss=1"
Guglielmini, J.Hennart, M.Badell, E.Toubiana, J.Criscuolo, A.Brisse, S.2021-07-20doi:10.1101/2021.07.18.452871Cold Spring Harbor Laboratory Press2021-07-20
<![CDATA[
Megasatellite formation and evolution in vertebrates
]]>
https://biorxiv.org/cgi/content/short/2021.07.19.452908v1?rss=1"
Descorps-Declere, S.Richard, G.-F.2021-07-20doi:10.1101/2021.07.19.452908Cold Spring Harbor Laboratory Press2021-07-20
<![CDATA[
FISH-quant v2: a scalable and modular analysis tool for smFISH image analysis
]]>
https://biorxiv.org/cgi/content/short/2021.07.20.453024v1?rss=1"
Imbert, A.Ouyang, W.Safieddine, A.Coleno, E.Zimmer, C.Bertrand, E.Walter, T.Mueller, F.2021-07-20doi:10.1101/2021.07.20.453024Cold Spring Harbor Laboratory Press2021-07-20
<![CDATA[
Discovery of genes that modulate flavivirus replication in an interferon-dependent manner
]]>
https://biorxiv.org/cgi/content/short/2021.07.20.453077v1?rss=1"
Lesage, S.Chazal, M.Beauclair, G.Batalie, D.Couderc, E.Lescure, A.Del Nery, E.Tangy, F.Martin, A.Manel, N.jouvenet, n.2021-07-20doi:10.1101/2021.07.20.453077Cold Spring Harbor Laboratory Press2021-07-20
<![CDATA[
PDZ-containing proteins targeted by the ACE2 receptor
]]>
https://biorxiv.org/cgi/content/short/2021.07.23.453470v1?rss=1"
Caillet-Saguy, C.Wolff, N.2021-07-23doi:10.1101/2021.07.23.453470Cold Spring Harbor Laboratory Press2021-07-23
<![CDATA[
Cell-type specific innate immune responses shape rabies virus tropism
]]>
https://biorxiv.org/cgi/content/short/2021.07.26.453802v1?rss=1"
Feige, L.Kozaki, T.Dias de Melo, G.Guillemot, V.Larrous, F.Ginhoux, F.Bourhy, H.2021-07-26doi:10.1101/2021.07.26.453802Cold Spring Harbor Laboratory Press2021-07-26
<![CDATA[
A dual barcoding approach to bacterial strain nomenclature: Genomic taxonomy of Klebsiella pneumoniae strains
]]>
https://biorxiv.org/cgi/content/short/2021.07.26.453808v1?rss=1"
7,000 genome sequences captured population structure discontinuities, which were used to guide the definition of 10 infra-specific genetic dissimilarity thresholds. The widely used 7-gene multilocus sequence typing (MLST) nomenclature was mapped onto MLSL sublineages (threshold: 190 allelic mismatches) and clonal group (threshold: 43) identifiers for backwards nomenclature compatibility. The taxonomy is publicly accessible through a community-curated platform (https://bigsdb.pasteur.fr/klebsiella), which also enables external users genomic sequences identification.
The proposed strain taxonomy combines two phylogenetically informative barcodes systems that provide full stability (LIN codes) and nomenclatural continuity with previous nomenclature (MLSL). This species-specific dual barcoding strategy for the genomic taxonomy of microbial strains is broadly applicable and should contribute to unify global and cross-sector collaborative knowledge on the emergence and microevolution of bacterial pathogens.
]]>Hennart, M.Guglielmini, J.Maiden, M. C. J.Jolley, K. A.Criscuolo, A.Brisse, S.2021-07-27doi:10.1101/2021.07.26.453808Cold Spring Harbor Laboratory Press2021-07-27
<![CDATA[
InDeep : 3D fully convolutional neural networks to assist in silico drug design on protein-protein interactions
]]>
https://biorxiv.org/cgi/content/short/2021.07.28.453974v1?rss=1"
Mallet, V.Ruano, L. C.Moine-Franel, A.Nilges, M.Druart, K.Bouvier, G.Sperandio, O.2021-07-29doi:10.1101/2021.07.28.453974Cold Spring Harbor Laboratory Press2021-07-29
<![CDATA[
Viruses of Asgard archaea
]]>
https://biorxiv.org/cgi/content/short/2021.07.29.453957v1?rss=1"
Medvedeva, S.Sun, J.Yutin, N.Koonin, E. V.Nunoura, T.Rinke, C.Krupovic, M.2021-07-30doi:10.1101/2021.07.29.453957Cold Spring Harbor Laboratory Press2021-07-30
<![CDATA[
Deficiency in cytosine DNA methylation leads to high chaperonin expression and tolerance to aminoglycosides in Vibrio cholerae
]]>
https://biorxiv.org/cgi/content/short/2021.07.29.454301v1?rss=1"
Carvalho, A.Mazel, D.Baharoglu, Z.2021-07-29doi:10.1101/2021.07.29.454301Cold Spring Harbor Laboratory Press2021-07-29
<![CDATA[
Concentration of intraflagellar transport proteins at the ciliary base is required for proper train injection
]]>
https://biorxiv.org/cgi/content/short/2021.08.02.454739v1?rss=1"
Jung, J.Santi-Rocca, J.Fort, C.Tinevez, J.-Y.Schietroma, C.BASTIN, P.2021-08-02doi:10.1101/2021.08.02.454739Cold Spring Harbor Laboratory Press2021-08-02
<![CDATA[
Selection for non-specific adhesion is a driver of FimH evolution increasing Escherichia coli biofilm capacity
]]>
https://biorxiv.org/cgi/content/short/2021.08.03.454899v1?rss=1"
YOSHIDA, M.THIRIET-RUPERT, S.MAYER, L.BELOIN, C.GHIGO, J.-M.2021-08-03doi:10.1101/2021.08.03.454899Cold Spring Harbor Laboratory Press2021-08-03
<![CDATA[
NAD kinase controls antibiotic susceptibility and pathogenic potential in Staphylococcus aureus
]]>
https://biorxiv.org/cgi/content/short/2021.08.09.455706v1?rss=1"
Leseigneur, C.Boucontet, L.Gorgette, O.Thouvenot, C.Colucci-Guyon, E.Dussurget, O.2021-08-09doi:10.1101/2021.08.09.455706Cold Spring Harbor Laboratory Press2021-08-09
<![CDATA[
A screening pipeline identifies a broad-spectrum inhibitor of bacterial AB toxins with cross protection against influenza A virus H1N1 and SARS-CoV-2
]]>
https://biorxiv.org/cgi/content/short/2021.08.13.454991v1?rss=1"
Wu, Y.Mahtal, N.Swistak, L.Sagadiev, S.Acharya, M.Demeret, C.Van der Werf, S.Guivel-Benhassine, F.Schwartz, O.Petracchini, S.Mettouchi, A.Paillares, E.Caramelle, L.Couvineau, P.Thai, R.Barbe, P.Keck, M.Brodin, P.Machelart, A.Sencio, V.Trottein, F.Sachse, M.Chicanne, G.Payrastre, B.Ville, F.Kreis, V.Popoff, M.-R.Johannes, L.Cintrat, J.-C.Barbier, J.Gillet, D.Lemichez, E.2021-08-16doi:10.1101/2021.08.13.454991Cold Spring Harbor Laboratory Press2021-08-16
<![CDATA[
The genomic signatures of natural selection in admixed human populations
]]>
https://biorxiv.org/cgi/content/short/2021.09.01.458503v1?rss=1"
Cuadros-Espinoza, S.Laval, G.Quintana-Murci, L.Patin, E.2021-09-01doi:10.1101/2021.09.01.458503Cold Spring Harbor Laboratory Press2021-09-01
<![CDATA[
Amphiregulin mediates non-cell-autonomous effect of senescence on reprogramming
]]>
https://biorxiv.org/cgi/content/short/2021.09.01.458621v1?rss=1"
Li, H.von Joest, M.Chen, C.Chiche, A.Matondo, M.Douche, T.2021-09-02doi:10.1101/2021.09.01.458621Cold Spring Harbor Laboratory Press2021-09-02
<![CDATA[
The Sec61 translocon is a therapeutic vulnerability in Multiple Myeloma
]]>
https://biorxiv.org/cgi/content/short/2021.09.05.459026v1?rss=1"
Domenger, A.Choisy, C.Baron, L.Mayau, V.Deriano, L.Arnulf, B.Bories, J.-C.Dadaglio, G.Demangel, C.2021-09-06doi:10.1101/2021.09.05.459026Cold Spring Harbor Laboratory Press2021-09-06
<![CDATA[
OCT4 activates a Suv39h1-repressive antisense lncRNA to couple histone H3 Lysine 9 methylation to pluripotency
]]>
https://biorxiv.org/cgi/content/short/2021.09.07.459323v1?rss=1"
Bernard, L. D.DUBOIS, A.Heurtier, V.Chervova, A.Tachtsidi, A.Gil, N.Owens, N.Vandormael-Pournin, S.Ulitsky, I.Cohen-Tannoudji, M.Navarro, P.2021-09-07doi:10.1101/2021.09.07.459323Cold Spring Harbor Laboratory Press2021-09-07
<![CDATA[
ShareLoc - an open platform for sharing localization microscopy data
]]>
https://biorxiv.org/cgi/content/short/2021.09.08.459385v1?rss=1"
Bai, J.Ouyang, W.Singh, M. K.Leterrier, C.Barthelemy, P.Barnett, S. F. H.Klein, T.Sauer, M.Kanchanawong, P.Bourg, N.Cohen, M. M.Lelandais, B.Zimmer, C.2021-09-09doi:10.1101/2021.09.08.459385Cold Spring Harbor Laboratory Press2021-09-09
<![CDATA[
A virus-encoded microRNA contributes to evade innate immune response during SARS-CoV-2 infection
]]>
https://biorxiv.org/cgi/content/short/2021.09.09.459577v1?rss=1"
Singh, M.Chazal, M.Quarato, P.Bourdon, L.Malabat, C.Vallet, T.Vignuzzi, M.van der Werf, S.Behillil, S.Donati, F.Sauvonnet, N.Nigro, G.Bourgine, M.Jouvenet, N.Cecere, G.2021-09-09doi:10.1101/2021.09.09.459577Cold Spring Harbor Laboratory Press2021-09-09
<![CDATA[
Optineurin links Hace1-dependent Rac ubiquitylation to integrin-mediated mechanotransduction to control bacterial invasion and cell division
]]>
https://biorxiv.org/cgi/content/short/2021.09.19.460967v1?rss=1"
Petracchini, S.Hamaoui, D.Doye, A.Asnacios, A.Fage, F.Vitiello, E.Balland, m.Janel, S.Lafont, F.Gupta, M.Ladoux, B.Gilleron, J.Maia, T. M.Impens, F.Gagnoux, L.Daugaard, M.Sorensen, P.Lemichez, E.Mettouchi, A.2021-09-20doi:10.1101/2021.09.19.460967Cold Spring Harbor Laboratory Press2021-09-20
<![CDATA[
Self-organized tissue mechanics underlie embryonic regulation
]]>
https://biorxiv.org/cgi/content/short/2021.10.08.463661v1?rss=1"
Caldarelli, P.Chamolly, A.Alegria-Prevot, O.Gros, J.Corson, F.2021-10-09doi:10.1101/2021.10.08.463661Cold Spring Harbor Laboratory Press2021-10-09
<![CDATA[
Localization of the putative recombinase Pf-int to the apicoplast of Plasmodium falciparum
]]>
https://biorxiv.org/cgi/content/short/2021.10.12.464051v1?rss=1"
Berglar, A. V.Vembar, S. S.Gopaul, D. N.2021-10-12doi:10.1101/2021.10.12.464051Cold Spring Harbor Laboratory Press2021-10-12
<![CDATA[
The cnf1 gene is associated to an expanding Escherichia coli ST131 H30Rx/C2 sublineage and confers a competitive advantage for host colonization
]]>
https://biorxiv.org/cgi/content/short/2021.10.13.464032v1?rss=1"
TSOUMTSA MEDA, L. L.LANDRAUD, L.PETRACCHINI, S.DESCORPS-DECLERE, S.PERTHAME, E.NAHORI, M.-a.RAMIREZ FINN, L.INGERSOLL, M. A.PATINO-NAVARETE, R.GLASER, P.DUSSURGET, O.DENAMUR, E.METTOUCHI, A.LEMICHEZ, E.2021-10-13doi:10.1101/2021.10.13.464032Cold Spring Harbor Laboratory Press2021-10-13
<![CDATA[
Zebrafish larvae as a powerful model to dissect protective innate immunity in response to Legionella pneumophila infection
]]>
https://biorxiv.org/cgi/content/short/2021.10.18.464513v1?rss=1"
Viana, F.Boucontet, L.Schator, D.Laghi, V.Ibranosyan, M.Jarraud, S.Colucci-Guyon, E.Buchrieser, C.2021-10-19doi:10.1101/2021.10.18.464513Cold Spring Harbor Laboratory Press2021-10-19
<![CDATA[
Specificities and commonalities of carbapenemase producing Escherichia coli isolated in France from 2012 to 2015.
]]>
https://biorxiv.org/cgi/content/short/2021.10.19.464995v1?rss=1"
Patino-Navarrete, R.Rosinski-Chupin, I.Cabanel, N.Zongo, p.-d.Hery, M.Oueslati, S.Girlich, D.Dortet, L.Bonnin, R.Naas, T.Glaser, P.2021-10-19doi:10.1101/2021.10.19.464995Cold Spring Harbor Laboratory Press2021-10-19
<![CDATA[
A dual involvement of Protocadherin-18a in stromal cell development guides the formation of a functional hematopoietic niche.
]]>
https://biorxiv.org/cgi/content/short/2021.10.19.465038v1?rss=1"
Touret, A.-L.Vivier, C.Schmidt, A.Herbomel, P.Murayama, E.2021-10-19doi:10.1101/2021.10.19.465038Cold Spring Harbor Laboratory Press2021-10-19
<![CDATA[
Bladder tissue-resident memory T cells are necessary and sufficient to mediate immunity to recurrent UTI
]]>
https://biorxiv.org/cgi/content/short/2021.10.28.466224v1?rss=1"
Rousseau, M.Lacerda Mariano, L.Canton, T.Ingersoll, M. A.2021-10-28doi:10.1101/2021.10.28.466224Cold Spring Harbor Laboratory Press2021-10-28
<![CDATA[
Tunneling nanotubes provide a novel route for SARS-CoV-2 spreading between permissive cells and to non-permissive neuronal cells.
]]>
https://biorxiv.org/cgi/content/short/2021.11.15.468633v1?rss=1"
Pepe, A.Pietropaoli, S.Vos, M.Barba-Spaeth, G.Zurzolo, C.2021-11-17doi:10.1101/2021.11.15.468633Cold Spring Harbor Laboratory Press2021-11-17
<![CDATA[
Plasmodium-encoded murine IL-6 impairs liver stage infection and elicits long-lasting sterilizing immunity
]]>
https://biorxiv.org/cgi/content/short/2021.11.16.468835v1?rss=1"
Belhimeur, S.Briquet, S.Peronet, R.Pham, J.Commere, P.-H.Amino, R.Scherf, A.Silvie, O.MECHERI, S.2021-11-16doi:10.1101/2021.11.16.468835Cold Spring Harbor Laboratory Press2021-11-16
<![CDATA[
High prevalence of Klebsiella pneumoniae in European food products: a multicentric study comparing culture and molecular detection methods
]]>
https://biorxiv.org/cgi/content/short/2021.11.24.469859v1?rss=1"
Rodrigues, C.Hauser, K.Cahill, N.Ligowska-Marzeta, M.Centorotola, G.Cornacchia, A.Garcia Fierro, R.Haenni, M.Moller Nielsen, E.Piveteau, P.Barbier, E.Morris, D.Pomilio, F.Brisse, S.2021-11-24doi:10.1101/2021.11.24.469859Cold Spring Harbor Laboratory Press2021-11-24
<![CDATA[
Interactions of SARS-CoV-2 protein E with cell junctions and polarity PDZ-containing proteins
]]>
https://biorxiv.org/cgi/content/short/2021.12.04.471219v1?rss=1"
Zhu, Y.Alvarez, F.Wolff, N.Mechaly, A.Brule, S.Neitthoffer, B.Etienne-Manneville, s.Haouz, A.Boeda, B.Caillet-Saguy, C.2021-12-06doi:10.1101/2021.12.04.471219Cold Spring Harbor Laboratory Press2021-12-06
<![CDATA[
Variable oxygen environments and DNMT2 determine the DNA cytosine epigenetic landscape of Plasmodium falciparum
]]>
https://biorxiv.org/cgi/content/short/2021.12.09.471905v1?rss=1"
80% A+T) for quantitative LC-MS/MS analysis of 5-hydroxymethylcytosine (5hmC), 5-formylcytosine (5fC) and 5-carboxylcytosine (5caC). We demonstrate the presence of 5hmC, 5fC and 5caC cytosine modifications in a DNMT2-only organism and observe striking ratio changes between 5mC and 5hmC during the 48-hour blood stage parasite development. Parasite-infected red blood cells cultured in different physiological oxygen concentrations revealed a shift in the cytosine modifications distribution towards the oxidized 5hmC and 5caC forms. In the absence of the canonical C5-DNA methyltransferase (DNMT1 and DNMT3A/B) in P. falciparum, we show that all cytosine modifications depend on the presence of DNMT2. We conclude that DNMT2 and oxygen levels are critical determinants that shape the dynamic cytosine epigenetic landscape in this human pathogen.
]]>Scherf, A.Hammam, E.Miled, S.Bonhomme, F.Arcangioli, B.Arimondo, P.2021-12-09doi:10.1101/2021.12.09.471905Cold Spring Harbor Laboratory Press2021-12-09
<![CDATA[
Considerable escape of SARS-CoV-2 variant Omicron to antibody neutralization
]]>
https://biorxiv.org/cgi/content/short/2021.12.14.472630v1?rss=1"
Planas, D.Saunders, N.Maes, P.Benhassine, F. G.Planchais, C.Porrot, F.Staropoli, I.Lemoine, F.Pere, H.Veyer, D.Puech, J.Rodary, J.Bolland, W. H.Buchrieser, J.Baele, G.Dellicour, S.Raymenants, J.Gorissen, S.Geenen, C.Vanmechelen, B.Wawina, T.Marti, J.Cuypers, L.Seve, A.Hocqueloux, L.Prazuck, T.Loriere, E. S.REY, F.Bruel, T.Mouquet, H.Andre, E.Schwartz, O.2021-12-15doi:10.1101/2021.12.14.472630Cold Spring Harbor Laboratory Press2021-12-15
<![CDATA[
Single-molecule imaging reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status
]]>
https://biorxiv.org/cgi/content/short/2021.12.20.473455v1?rss=1"
Momboisse, F.Nardi, G.Colin, P.Hery, M.Cordeiro, N.Schwartz, O.Sauvonnet, N.Arenzana-Seisdedos, F.Lagache, T.Lagane, B.Olivo-Marin, J.-C.Brelot, A.2021-12-20doi:10.1101/2021.12.20.473455Cold Spring Harbor Laboratory Press2021-12-20
<![CDATA[
Fusogenicity and neutralization sensitivity of the SARS-CoV-2 Delta sublineage AY.4.2
]]>
https://biorxiv.org/cgi/content/short/2022.01.07.475248v1?rss=1"
Saunders, N.Planas, D.Bolland, W. H.Rodriguez, C.Fourati, S.Buchrieser, J.Planchais, C.Prot, M.Staropoli, I.Guivel-Benhassine, F.Porrot, F.Veyer, D.Pere, H.Robillard, N.Saliba, M.Baidaliuk, A.Seve, A.Hocqueloux, L.Prazuck, T.Mouquet, H.Simon-Loriere, E.Bruel, T.Pawlotsky, J.-M.Schwartz, O.2022-01-10doi:10.1101/2022.01.07.475248Cold Spring Harbor Laboratory Press2022-01-10
<![CDATA[
The genomic landscape of contemporary western Remote Oceanians
]]>
https://biorxiv.org/cgi/content/short/2022.01.10.475623v1?rss=1"
Arauna, L. R.Bergstedt, J.Choin, J.Mendoza-Revilla, J.Harmant, C.Roux, M.Mas-Sandoval, A.Lemee, L.Colleran, H.Francois, A.Valentin, F.Cassar, O.Gessain, A.Quintana-Murci, L.Patin, E.2022-01-10doi:10.1101/2022.01.10.475623Cold Spring Harbor Laboratory Press2022-01-10
<![CDATA[
The AAA+ ATPase RavA-ViaA complex sensitizes Escherichia coli to aminoglycosides under anaerobic low energy conservation conditions
]]>
https://biorxiv.org/cgi/content/short/2022.01.13.476284v1?rss=1"
El Khoury, J.Zamarreno, J.Huguenot, A.Py, B.Barras, F.2022-01-14doi:10.1101/2022.01.13.476284Cold Spring Harbor Laboratory Press2022-01-14
<![CDATA[
Functional variability in adhesion and flocculation of yeast megasatellite genes
]]>
https://biorxiv.org/cgi/content/short/2022.01.14.476295v1?rss=1"
Saguez, C.Viterbo, D.Descorps-Declere, S.Cormack, B. P.Dujon, B.Richard, G.-F.2022-01-17doi:10.1101/2022.01.14.476295Cold Spring Harbor Laboratory Press2022-01-17
<![CDATA[
Dynamics and structural changes of calmodulin upon interaction with its potent antagonist calmidazolium
]]>
https://biorxiv.org/cgi/content/short/2022.01.19.474921v1?rss=1"
View larger version (40K):
org.highwire.dtl.DTLVardef@b0c76org.highwire.dtl.DTLVardef@15f462forg.highwire.dtl.DTLVardef@1f8e57forg.highwire.dtl.DTLVardef@1a33575_HPS_FORMAT_FIGEXP M_FIG C_FIG Calmidazolium is a potent and widely used inhibitor of calmodulin, a major mediator of calcium-signaling in eukaryotic cells. Structural characterization of calmidazolium-binding to calmodulin reveals that it triggers open-to-closed conformational changes similar to those induced by calmodulin-binding peptides derived from enzyme targets. These results open the way to rationally design new and more selective inhibitors of calmodulin.
]]>Leger, C.Pitard, I.Sadi, M.Carvalho, N.Brier, S.Mechaly, A.Raoux Barbot, D.Davi, M.Hoos, S.Weber, P.Vachette, P.Durand, D.Haouz, A.Guijarro, J. I.Ladant, D.CHENAL, A.2022-01-21doi:10.1101/2022.01.19.474921Cold Spring Harbor Laboratory Press2022-01-21
<![CDATA[
Genomic library of Bordetella
]]>
https://biorxiv.org/cgi/content/short/2022.01.20.475763v1?rss=1"
Bridel, S.Bouchez, V.Hauck, S.Brancotte, B.Armatys, N.Landier, A.Muhle, E.Guillot, S.Toubiana, J.Maiden, M. C.Jolley, K. A.Brisse, S.2022-01-20doi:10.1101/2022.01.20.475763Cold Spring Harbor Laboratory Press2022-01-20
<![CDATA[
An intranasal lentiviral booster broadens immune recognition of SARS-CoV-2 variants and reinforces the waning mRNA vaccine-induced immunity that it targets to lung mucosa
]]>
https://biorxiv.org/cgi/content/short/2022.01.30.478159v1?rss=1"
Vesin, B.Lopez, J.Noirat, A.Authie, P.Fert, I.Le Chevalier, F.Moncoq, F.Nemirov, K.Blanc, C.Planchais, C.Mouquet, H.Guinet, F.Hardy, D.Gerke, C.Anna, F.Bourgine, M.MAJLESSI, L.Charneau, P.2022-01-31doi:10.1101/2022.01.30.478159Cold Spring Harbor Laboratory Press2022-01-31
<![CDATA[
Decoding rRNA Sequences for Improved Metagenomics in Sylvatic Mosquito Species
]]>
https://biorxiv.org/cgi/content/short/2022.02.01.478639v1?rss=1"
Koh, C.Frangeul, L.Blanc, H.Ngoagouni, C.Boyer, S.Dussart, P.Grau, N.Girod, R.Duchemin, J.-B.Saleh, M. C.2022-02-03doi:10.1101/2022.02.01.478639Cold Spring Harbor Laboratory Press2022-02-03
<![CDATA[
Type B and Type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD
]]>
https://biorxiv.org/cgi/content/short/2022.02.04.479088v1?rss=1"
Krischuns, T.Isel, C.Drncova, P.Lukarska, M.Pflug, A.Paisant, S.Navratil, V.Cusack, S.Naffakh, N.2022-02-04doi:10.1101/2022.02.04.479088Cold Spring Harbor Laboratory Press2022-02-04
<![CDATA[
Non-essential tRNA and rRNA modifications impact the bacterial response to sub-MIC antibiotic stress
]]>
https://biorxiv.org/cgi/content/short/2022.02.06.479318v1?rss=1"
Babosan, A.Fruchard, L.Krin, E.Carvalho, A.Mazel, D.Baharoglu, Z.2022-02-06doi:10.1101/2022.02.06.479318Cold Spring Harbor Laboratory Press2022-02-06
<![CDATA[
Relevance study of vector competence and insecticide resistance in Aedes aegypti laboratory lines
]]>
https://biorxiv.org/cgi/content/short/2022.02.12.480187v1?rss=1"
Wang, L.Fontaine, A.Gaborit, P.Guidez, A.Issaly, J.Girod, R.Kazanji, M.Rousset, D.Vignuzzi, M.Epelboin, Y.Dusfour, I.2022-02-13doi:10.1101/2022.02.12.480187Cold Spring Harbor Laboratory Press2022-02-13
<![CDATA[
Is it the same strain? Defining genomic epidemiology thresholds tailored to individual outbreaks
]]>
https://biorxiv.org/cgi/content/short/2022.02.15.480545v1?rss=1"
Duval, A.opatowski, L.Brisse, S.2022-02-15doi:10.1101/2022.02.15.480545Cold Spring Harbor Laboratory Press2022-02-15
<![CDATA[
Synaptic basis of a sub-second representation of time
]]>
https://biorxiv.org/cgi/content/short/2022.02.16.480693v1?rss=1"
Barri, A.Wiechart, M. T.Jazayeri, M.DiGregorio, D.2022-02-17doi:10.1101/2022.02.16.480693Cold Spring Harbor Laboratory Press2022-02-17
<![CDATA[
Mitotic bookmarking by CTCF controls selected genes during the fast post-mitotic genome reactivation of ES cells
]]>
https://biorxiv.org/cgi/content/short/2022.02.20.481195v1?rss=1"
Chervova, A.Festuccia, N.Dubois, A.Navarro, P.2022-02-20doi:10.1101/2022.02.20.481195Cold Spring Harbor Laboratory Press2022-02-20
<![CDATA[
Transcriptomic landscapes of SARS-CoV-2-infected and bystander lung cells reveal a selective upregulation of NF-κB-dependent coding and non-coding proviral transcripts
]]>
https://biorxiv.org/cgi/content/short/2022.02.25.481978v1?rss=1"
Szachnowski, U.Bhargava, A.Chazal, M.Foretek, D.Aicher, S.-M.Pipoli da Fonseca, J.Jeannin, P.Beauclair, G.Monot, M.Morillon, A.Jouvenet, N.2022-02-26doi:10.1101/2022.02.25.481978Cold Spring Harbor Laboratory Press2022-02-26
<![CDATA[
IntegronFinder 2.0: identification and analysis of integrons across Bacteria, with a focus on antibiotic resistance in Klebsiella
]]>
https://biorxiv.org/cgi/content/short/2022.02.28.482270v1?rss=1"
Rocha, E. P. C.Cury, J.PERRIN, A.Haudiquet, M.Neron, B.Littner, E.2022-03-01doi:10.1101/2022.02.28.482270Cold Spring Harbor Laboratory Press2022-03-01
<![CDATA[
Alcam-a and Pdgfr-α are essential for the development of sclerotome derived stromal cells that support hematopoiesis in vivo.
]]>
https://biorxiv.org/cgi/content/short/2022.03.02.482709v1?rss=1"
Murayama, E.Vivier, C.Schmidt, A.Touret, A.-L.Herbomel, P.2022-03-02doi:10.1101/2022.03.02.482709Cold Spring Harbor Laboratory Press2022-03-02
<![CDATA[
Gender-based disparities and biases in science: observational study of a virtual conference
]]>
https://biorxiv.org/cgi/content/short/2022.03.07.483337v1?rss=1"
Zhang, J.Torchet, R.Julienne, H.2022-03-08doi:10.1101/2022.03.07.483337Cold Spring Harbor Laboratory Press2022-03-08
<![CDATA[
First description of a Yersinia pseudotuberculosis clonal outbreak in France, confirmed using a new core genome multilocus sequence typing method
]]>
https://biorxiv.org/cgi/content/short/2022.03.23.485572v1?rss=1"
Savin, C.Le Guern, A.-S.Chereau, F.Guglielmini, J.Heuze, G.Demeure, C.Pizarro-Cerda, J.2022-03-25doi:10.1101/2022.03.23.485572Cold Spring Harbor Laboratory Press2022-03-25
<![CDATA[
Volatile hydrogen cyanide released by Pseudomonas aeruginosa provides a competitive advantage over Staphylococcus aureus in biofilm and in vivo lung environments
]]>
https://biorxiv.org/cgi/content/short/2022.03.24.484598v1?rss=1"
Letoffe, S.Wu, Y.Darch, S. E.Beloin, C.Whiteley, M.Touqui, L.Ghigo, J.-M.2022-03-24doi:10.1101/2022.03.24.484598Cold Spring Harbor Laboratory Press2022-03-24
<![CDATA[
Recognition of copy-back defective interfering rabies virus genomes by RIG-I triggers the antiviral response against vaccine strains
]]>
https://biorxiv.org/cgi/content/short/2022.03.24.485606v1?rss=1"
AOUADI, w.Najburg, V.Legendre, R.Varet, H.Kergoat, L.Tangy, F.Larrous, F.Komarova, A.Bourhy, H.2022-03-25doi:10.1101/2022.03.24.485606Cold Spring Harbor Laboratory Press2022-03-25
<![CDATA[
Small Molecules Restore Azole Activity Against Drug-Tolerant and Drug-Resistant Candida Isolates
]]>
https://biorxiv.org/cgi/content/short/2022.03.31.486631v1?rss=1"
Alabi, P. E.Gautier, C.Murphy, T. P.Sello, J. K.Ene, I. V.2022-03-31doi:10.1101/2022.03.31.486631Cold Spring Harbor Laboratory Press2022-03-31
<![CDATA[
Potent Human Broadly SARS-CoV-2 Neutralizing IgA and IgG Antibodies Effective Against Omicron BA.1 and BA.2
]]>
https://biorxiv.org/cgi/content/short/2022.04.01.486719v1?rss=1"
Planchais, C.Fernandez, I.Bruel, T.Dias de Melo, G.Prot, M.Beretta, M.Guardado-Calvo, P.Dufloo, J.Molinos-Albert, L. M.Backovic, M.Chiaravalli, J.Giraud, E.Vesin, B.Conquet, L.Grzelak, L.Planas, D.Staropoli, I.Guivel-Benhassine, F.Boulle, M.Cervantes-Gonzalez, M.French COVID Cohort Study Group,CORSER Study Group,Ungeheuer, M.-N.Charneau, P.van der Werf, S.Agou, F.Dimitrov, J. D.Simon-Loriere, E.Bourhy, H.Montagutelli, X.Rey, F. A.Schwartz, O.Mouquet, H.2022-04-01doi:10.1101/2022.04.01.486719Cold Spring Harbor Laboratory Press2022-04-01
<![CDATA[
Dynamics of drug response in single mycobacterial cells by microfluidic dose-response assay
]]>
https://biorxiv.org/cgi/content/short/2022.04.03.486879v1?rss=1"
Mistretta, M.Gangneux, N.Manina, G.2022-04-03doi:10.1101/2022.04.03.486879Cold Spring Harbor Laboratory Press2022-04-03
<![CDATA[
High frequency spike inference with particle Gibbs sampling
]]>
https://biorxiv.org/cgi/content/short/2022.04.05.487201v1?rss=1"
Diana, G.Sermet, B. S.DiGregorio, D. A.2022-04-08doi:10.1101/2022.04.05.487201Cold Spring Harbor Laboratory Press2022-04-08
<![CDATA[
Trim33 conditions the lifespan of primitive macrophages and onset of definitive macrophage production
]]>
https://biorxiv.org/cgi/content/short/2022.04.06.487382v1?rss=1"
Demy, D. L.Touret, A.-L.Lancino, M.Tauzin, M.Capuana, L.Pierre, C.Herbomel, P.2022-04-08doi:10.1101/2022.04.06.487382Cold Spring Harbor Laboratory Press2022-04-08
<![CDATA[
Pneumococcus triggers NFkB degradation in COMMD2 aggresome-like bodies.
]]>
https://biorxiv.org/cgi/content/short/2022.04.08.487599v1?rss=1"
Connor, M. G.Sanchez, L.Chevalier, C.Carvalho, F.Eldridge, M. J. G.Chaze, T.Matondo, M.Weight, C.Heyderman, R. S.Enninga, J.Hamon, M. A.2022-04-08doi:10.1101/2022.04.08.487599Cold Spring Harbor Laboratory Press2022-04-08
<![CDATA[
A maximum mean discrepancy approach reveals subtle changes in α-synuclein dynamics
]]>
https://biorxiv.org/cgi/content/short/2022.04.11.487825v1?rss=1"
Verdier, H.Laurent, F.Casse, A.Vestergaard, C. L.Specht, C. G.Masson, J.-B.2022-04-11doi:10.1101/2022.04.11.487825Cold Spring Harbor Laboratory Press2022-04-11
<![CDATA[
Human peroxiredoxin 6 is essential for malaria parasites and provides a host-based drug target
]]>
https://biorxiv.org/cgi/content/short/2022.04.11.487889v1?rss=1"
Wagner, M. P.Formaglio, P.Gorgette, O.Dziekan, J. M.Huon, C.Berneburg, I.Rahlfs, S.Barale, J.-C.Feinstein, S. I.Fisher, A. B.Menard, D.Bozdech, Z.Amino, R.Touqui, L.Chitnis, C. E.2022-04-11doi:10.1101/2022.04.11.487889Cold Spring Harbor Laboratory Press2022-04-11
<![CDATA[
Microbiota-induced active translocation of peptidoglycan across the intestinal barrier dictates its within-host dissemination
]]>
https://biorxiv.org/cgi/content/short/2022.04.20.488924v1?rss=1"
Wheeler, R.Bastos, P. A. D.Disson, O.Rifflet, A.Spielbauer, J.Lecuit, M.Boneca, I. G.2022-04-21doi:10.1101/2022.04.20.488924Cold Spring Harbor Laboratory Press2022-04-21
<![CDATA[
Core genome sequencing and genotyping of Leptospira interrogans in clinical samples by target capture sequencing
]]>
https://biorxiv.org/cgi/content/short/2022.04.29.490004v1?rss=1"
8X), we could unambigously identify L. interrogans sv Icterohaemorrhagiae (14 samples), L. kirschneri sv Grippotyphosa (4 samples) and L. interrogans sv Pyrogenes (1 sample) as the infecting strain.
In conclusion, we obtained for most of our biological samples high quality genomic data at suitable coverage for confident core genome genotyping of the agent of leptospirosis. The ability to generate culture-free genomic data opens new opportunities to better understand the epidemiology and evolution of this fastidious pathogen.
]]>Grillova, L.Cokelaer, T.Mariet, J.-F.Pipoli da Fonseca, J.PICARDEAU, M.2022-04-29doi:10.1101/2022.04.29.490004Cold Spring Harbor Laboratory Press2022-04-29
<![CDATA[
Decreased in vitro dihydroartemisinin sensitivity in malaria parasites infecting sickle cell disease patients
]]>
https://biorxiv.org/cgi/content/short/2022.04.29.490119v1?rss=1"
Gnondjui, A. A.Toure, A. O.Ako, B. A.Koui, S. T.Assohoun, S. E.Gbessi, E. A.N'guessan, L. T.Tuo, K.Beorou, S.Assi, S. B.Yapo, F.Sanogo, I.Jambou, R.2022-05-02doi:10.1101/2022.04.29.490119Cold Spring Harbor Laboratory Press2022-05-02
<![CDATA[
Leishmania allelic selection during experimental sand fly infection correlates with mutational signatures of oxidative DNA damage
]]>
https://biorxiv.org/cgi/content/short/2022.05.02.490304v1?rss=1"
Bussotti, G.Li, B.Pescher, P.Vojtkova, B.Louradour, I.Pruzinova, K.Sadlova, J.Volf, P.Spaeth, G. F.2022-05-02doi:10.1101/2022.05.02.490304Cold Spring Harbor Laboratory Press2022-05-02
<![CDATA[
Carbapenem heteroresistance of KPC-producing Klebsiella pneumoniae results from tolerance, persistence and resistance.
]]>
https://biorxiv.org/cgi/content/short/2022.05.03.490393v1?rss=1"
Chiarelli, A.Cabanel, N.Rosinski-Chupin, I.Obadia, T.Ruimy, R.Naas, T.Bonnin, R.Glaser, P.2022-05-03doi:10.1101/2022.05.03.490393Cold Spring Harbor Laboratory Press2022-05-03
<![CDATA[
Intermittent antibiotic treatment of bacterial biofilms favors the rapid evolution of resistance
]]>
https://biorxiv.org/cgi/content/short/2022.05.03.490405v1?rss=1"
Usui, M.Yoshii, Y.Thiriet-Rupert, S.Ghigo, J.-M.BELOIN, C.2022-05-03doi:10.1101/2022.05.03.490405Cold Spring Harbor Laboratory Press2022-05-03
<![CDATA[
ACE2 nanoparticles prevent cell entry of SARS-CoV-2
]]>
https://biorxiv.org/cgi/content/short/2022.05.05.490805v1?rss=1"
Sauvanet, C.Lemos, M.Bezault, A.Rodriguez de Francisco, B.Chan, M. C.Hui, K. P.Ng, K.-c.Nicholls, J. M.Volkmann, N.Hanein, D.2022-05-06doi:10.1101/2022.05.05.490805Cold Spring Harbor Laboratory Press2022-05-06
<![CDATA[
Parvimonas micra, an oral pathobiont associated with colorectal cancer, epigenetically reprograms human primary intestinal epithelial cells
]]>
https://biorxiv.org/cgi/content/short/2022.05.14.491935v1?rss=1"
Bergsten, E.Mestivier, D.Donnadieu, F.Pedron, T.Tsoumtsa, L.Lemichez, E.Gorgette, O.Volant, S.Doukani, A.Sansonetti, P. J.Sobhani, I.Nigro, G.2022-05-14doi:10.1101/2022.05.14.491935Cold Spring Harbor Laboratory Press2022-05-14
<![CDATA[
The selection of antibiotic- and bacteriophage-resistant Pseudomonas aeruginosa is prevented by their combination
]]>
https://biorxiv.org/cgi/content/short/2022.05.25.493369v1?rss=1"
Ferran, A. A.Lacroix, M. Z.Gourbeyre, O.Huesca, A.Gaborieau, B.Debarbieux, L.Bousquet-Melou, A.2022-05-25doi:10.1101/2022.05.25.493369Cold Spring Harbor Laboratory Press2022-05-25
<![CDATA[
IRF8 regulates efficacy of therapeutic anti-CD20 monoclonal antibodies
]]>
https://biorxiv.org/cgi/content/short/2022.06.09.495444v1?rss=1"
Grzelak, L.Roesch, F.Vaysse, A.Biton, A.Porrot, F.Commere, P.-H.Planchais, C.Mouquet, H.Vignuzzi, M.Bruel, T.Schwartz, O.2022-06-10doi:10.1101/2022.06.09.495444Cold Spring Harbor Laboratory Press2022-06-10
<![CDATA[
Single locus phosphoproteomics reveals phosphorylation of RPA-1 is required for generation of single-strand DNA following a break at a subtelomeric locus.
]]>
https://biorxiv.org/cgi/content/short/2022.06.15.496243v1?rss=1"
6500 phosphorylation sites, including a core set of 211 DSB responsive phosphorylation sites. Along with phosphorylation of canonical DNA damage factors, we find that there is a striking distinction between the proteins phosphorylated in response to a chromosome internal DSB and one at the active BES and describe a single phosphorylation event on Replication factor A (RPA) 1 that is required for efficient resection at a bloodstream form expression site.
]]>Mclaughlin, E.Dujeancourt-Henry, A.Chaze, T.Matondo, M.Gianetto, Q. G.Urbaniak, M. D.Glover, L.2022-06-15doi:10.1101/2022.06.15.496243Cold Spring Harbor Laboratory Press2022-06-15
<![CDATA[
DNA-PKcs regulates myogenesis in an AKT-dependent manner independent of induced DNA damage
]]>
https://biorxiv.org/cgi/content/short/2022.06.23.497315v1?rss=1"
Sutcu, H. H.Ricchetti, M.2022-06-23doi:10.1101/2022.06.23.497315Cold Spring Harbor Laboratory Press2022-06-23
<![CDATA[
Phage-plasmids spread antibiotic resistance genes through infection and lysogenic conversion
]]>
https://biorxiv.org/cgi/content/short/2022.06.24.497495v1?rss=1"
Pfeifer, E.Bonnin, R.Rocha, E. P. C.2022-06-25doi:10.1101/2022.06.24.497495Cold Spring Harbor Laboratory Press2022-06-25
<![CDATA[
Genetic adaptation to pathogens and increased risk of inflammatory disorders in post-Neolithic Europe
]]>
https://biorxiv.org/cgi/content/short/2022.07.02.498543v1?rss=1"
Kerner, G.Neehus, A.-L.Abel, L.Casanova, J.-L.Patin, E.Laval, G.Quintana-Murci, L.2022-07-03doi:10.1101/2022.07.02.498543Cold Spring Harbor Laboratory Press2022-07-03
<![CDATA[
Towards solving the conundrum of plasmid mobility: networks of functional dependencies shape plasmid transfer
]]>
https://biorxiv.org/cgi/content/short/2022.07.04.498229v1?rss=1"
Ares-Arroyo, M.Coluzzi, C.Rocha, E. P. C.2022-07-04doi:10.1101/2022.07.04.498229Cold Spring Harbor Laboratory Press2022-07-04
<![CDATA[
stuart: an R package for the curation of SNP genotypes from experimental crosses
]]>
https://biorxiv.org/cgi/content/short/2022.07.06.498978v1?rss=1"
Bourdon, M.Montagutelli, X.2022-07-06doi:10.1101/2022.07.06.498978Cold Spring Harbor Laboratory Press2022-07-06
<![CDATA[
Impact and mitigation of sampling bias to determine viral spread: evaluating discrete phylogeography through CTMC modeling and structured coalescent model approximations
]]>
https://biorxiv.org/cgi/content/short/2022.07.07.498932v1?rss=1"
Layan, M.Mueller, N. F.Dellicour, S.De Maio, N.Bourhy, H.Cauchemez, S.Baele, G.2022-07-08doi:10.1101/2022.07.07.498932Cold Spring Harbor Laboratory Press2022-07-08
<![CDATA[
Competition between phage-resistance mechanisms determines the outcome of bacterial co-existence
]]>
https://biorxiv.org/cgi/content/short/2022.07.11.499539v1?rss=1"
Rendueles, O.de Sousa, J. A.Rocha, E. P. C.2022-07-12doi:10.1101/2022.07.11.499539Cold Spring Harbor Laboratory Press2022-07-12
<![CDATA[
Cohesin is involved in transcriptional repression of stage-specific genes in the human malaria parasite
]]>
https://biorxiv.org/cgi/content/short/2022.07.21.500927v1?rss=1"
Rosa, C.Singh, P.Sinha, A.Preiser, P. R.Dedon, P. C.Baumgarten, S.Scherf, A.Bryant, J. M.2022-07-21doi:10.1101/2022.07.21.500927Cold Spring Harbor Laboratory Press2022-07-21
<![CDATA[
L.interrogans prevents macrophage death and pyroptotic IL1β release through its lipopolysaccharide
]]>
https://biorxiv.org/cgi/content/short/2022.07.25.501344v1?rss=1"
Bonhomme, D.Hernandez-Trejo, V.Papadopoulos, S.Pigache, R.Fanton d'Andon, M.Outlioua, A.GOMPERTS BONECA, I.Werts, C.2022-07-26doi:10.1101/2022.07.25.501344Cold Spring Harbor Laboratory Press2022-07-26
<![CDATA[
Poor sensitivity of iPSC-derived neural progenitors and glutamatergic neurons to SARS-CoV-2
]]>
https://biorxiv.org/cgi/content/short/2022.07.25.501370v1?rss=1"
Zivaljic, M.Hubert, M.Grzelak, L.Sansone, G.Maskos, U.Schwartz, O.2022-07-25doi:10.1101/2022.07.25.501370Cold Spring Harbor Laboratory Press2022-07-25
<![CDATA[
MEPSi: A tool for simulating tomograms of membrane-embedded proteins
]]>
https://biorxiv.org/cgi/content/short/2022.07.27.501771v1?rss=1"
View larger version (27K):
org.highwire.dtl.DTLVardef@120b44eorg.highwire.dtl.DTLVardef@1d9056org.highwire.dtl.DTLVardef@ef327aorg.highwire.dtl.DTLVardef@1daf773_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>Rodriguez de Francisco, B.Bezault, A.Xu, X.-P.Hanein, D.Volkmann, N.2022-07-29doi:10.1101/2022.07.27.501771Cold Spring Harbor Laboratory Press2022-07-29
<![CDATA[
Characterization of heterogeneity in nanodisc samples using Feret signatures
]]>
https://biorxiv.org/cgi/content/short/2022.07.28.501900v1?rss=1"
View larger version (22K):
org.highwire.dtl.DTLVardef@19ea37aorg.highwire.dtl.DTLVardef@1fed1aeorg.highwire.dtl.DTLVardef@781962org.highwire.dtl.DTLVardef@ca7859_HPS_FORMAT_FIGEXP M_FIG C_FIG HIGHLIGHTSO_LINew methodology to characterize nanodiscs based on Feret signatures
C_LIO_LIFeret signatures distinguish nanodisc morphologies and compositions
C_LIO_LIAnalysis is highly sensitive to sample quality
C_LIO_LIMethod selected condition to solve structure of small membrane protein Bcl-xL
C_LI
]]>Vilela, F.Bezault, A.Rodrigues de Francisco, B.Sauvanet, C.Xu, X.-P.Swift, M. F.Yao, Y.Marrasi, F. M.Hanein, D.Volkmann, N.2022-07-28doi:10.1101/2022.07.28.501900Cold Spring Harbor Laboratory Press2022-07-28
<![CDATA[
Genetic drivers of chromosomal integron stability
]]>
https://biorxiv.org/cgi/content/short/2022.08.03.502626v1?rss=1"
Richard, E.Darracq, B.Littner, E.Vit, C.Whiteway, C.Bos, J.Fournes, F.Garriss, G.Conte, V.Lapaillerie, D.Parissi, V.Rousset, F.Skovgaard, O.Bikard, D.Rocha, E.Mazel, D.Loot, C.2022-08-05doi:10.1101/2022.08.03.502626Cold Spring Harbor Laboratory Press2022-08-05
<![CDATA[
Phages against non-capsulated Klebsiella pneumoniae: broader host range, slower resistance
]]>
https://biorxiv.org/cgi/content/short/2022.08.04.502604v1?rss=1"
Lourenco, M.Osbelt, L.Passet, V.Gravey, F.Strowig, T.Rodrigues, C.Brisse, S.2022-08-04doi:10.1101/2022.08.04.502604Cold Spring Harbor Laboratory Press2022-08-04
<![CDATA[
COVID-19 pandemic responses may impact the spread of antibiotic-resistant bacteria: a modelling study
]]>
https://biorxiv.org/cgi/content/short/2022.08.08.503267v1?rss=1"
Kovacevic, A.Smith, D. R. M.Rahbe, E.Novelli, S.Henriot, P.Temime, L.Opatowski, L.2022-08-09doi:10.1101/2022.08.08.503267Cold Spring Harbor Laboratory Press2022-08-09
<![CDATA[
Collateral impacts of pandemic COVID-19 drive the nosocomial spread of antibiotic resistance
]]>
https://biorxiv.org/cgi/content/short/2022.08.15.503946v1?rss=1"
Smith, D. R. M.Shirreff, G.Temime, L.Opatowski, L.2022-08-16doi:10.1101/2022.08.15.503946Cold Spring Harbor Laboratory Press2022-08-16
<![CDATA[
3D reconstruction of the cerebellar germinal layer reveals intercytoplasmic connections between developing granule cells
]]>
https://biorxiv.org/cgi/content/short/2022.08.21.504684v1?rss=1"
Cordero Cervantes, D.Khare, H.Wilson, A. M.Mendoza, N. D.Coulon--Mahdi, O.Lichtman, J. W.Zurzolo, C.2022-08-21doi:10.1101/2022.08.21.504684Cold Spring Harbor Laboratory Press2022-08-21
<![CDATA[
Leptospiral lipopolysaccharide dampens inflammation through upregulation of autophagy adaptor p62 and NRF2 signaling in macrophages
]]>
https://biorxiv.org/cgi/content/short/2022.08.24.505079v1?rss=1"
Bonhomme, D.Santecchia, I.Escoll Guerrero, P.Vernel-Pauillac, F.Boneca, I. G.Werts, C.2022-08-24doi:10.1101/2022.08.24.505079Cold Spring Harbor Laboratory Press2022-08-24
<![CDATA[
Neuroinvasion and anosmia are independent phenomena upon infection with SARS-CoV-2 and its variants
]]>
https://biorxiv.org/cgi/content/short/2022.08.31.505985v1?rss=1"
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org.highwire.dtl.DTLVardef@8225ceorg.highwire.dtl.DTLVardef@80342aorg.highwire.dtl.DTLVardef@e0dfd1org.highwire.dtl.DTLVardef@1861e13_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>de Melo, G. D.Perraud, V.Alvarez, F.Vieites-Prado, A.Kim, S.Kergoat, L.Trueb, B. S.Tichit, M.Piazza, A.Thierry, A.Hardy, D.Wolff, N.Munier, S.Koszul, R.Simon-Loriere, E.Thiel, V.Lecuit, M.Lledo, P.-M.Renier, N.Larrous, F.Bourhy, H.2022-08-31doi:10.1101/2022.08.31.505985Cold Spring Harbor Laboratory Press2022-08-31
<![CDATA[
Variable effects on virulence of bacteriophage resistance mechanisms in extraintestinal pathogenic Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/2022.09.01.506217v1?rss=1"
Gaborieau, B.Delattre, R.Adiba, S.Clermont, O.Denamur, E.Ricard, J.-D.Debarbieux, L.2022-09-02doi:10.1101/2022.09.01.506217Cold Spring Harbor Laboratory Press2022-09-02
<![CDATA[
Rapid emergence of extensively drug-resistant Shigella sonnei in France
]]>
https://biorxiv.org/cgi/content/short/2022.09.07.506808v1?rss=1"
Lefevre, S.Njamkepo, E.Feldman, S.Ruckly, C.Carle, I.Lejay-Collin, M.Fabre, L.Yassine, I.Frezal, L.Pardos de la Gandara, M.Fontanet, A.Weill, F.-X.2022-09-09doi:10.1101/2022.09.07.506808Cold Spring Harbor Laboratory Press2022-09-09
<![CDATA[
Characterization of TelD, an LXG effector of Streptococcus gallolyticus, antagonized by a non-canonical immunity protein
]]>
https://biorxiv.org/cgi/content/short/2022.09.07.506920v1?rss=1"
Teh, W. K.Ding, Y.Gubellini, F.Filloux, A.Poyart, C.Dramsi, S.Givskov, M.2022-09-07doi:10.1101/2022.09.07.506920Cold Spring Harbor Laboratory Press2022-09-07
<![CDATA[
Immunometabolic profiling of in vitro and ex vivo Leishmania-infected macrophages (LIMs) reveals unique polarization and bioenergetic signatures
]]>
https://biorxiv.org/cgi/content/short/2022.09.08.507100v1?rss=1"
Zhang, S.Lecoeur, H.Varet, H.Legendre, R.Mahtal, N.Proux, C.Aulner, N.Short, S.Grandjean, C.Bousso, P.Prina, E.Spaeth, G. F.2022-09-08doi:10.1101/2022.09.08.507100Cold Spring Harbor Laboratory Press2022-09-08
<![CDATA[
A new route for integron cassette dissemination among bacterial genomes
]]>
https://biorxiv.org/cgi/content/short/2022.09.11.507474v1?rss=1"
Loot, C.Millot, G.Richard, E.Darracq, B.Vit, C.Parissi, V.Lemoine, F.Niault, T.Cury, J.Rocha, E. P.Mazel, D.2022-09-13doi:10.1101/2022.09.11.507474Cold Spring Harbor Laboratory Press2022-09-13
<![CDATA[
Leishmania amazonensis controls macrophage-regulated cell death to establish chronic infection in vitro and in vivo
]]>
https://biorxiv.org/cgi/content/short/2022.09.14.507851v1?rss=1"
Lecoeur, H.Zhang, S.Varet, H.Legendre, R.Proux, C.Granjean, C.Bousso, P.Prina, E.Spaeth, G. F.2022-09-14doi:10.1101/2022.09.14.507851Cold Spring Harbor Laboratory Press2022-09-14
<![CDATA[
Identification and characterization of thousands of bacteriophage satellites across bacteria
]]>
https://biorxiv.org/cgi/content/short/2022.09.14.508007v1?rss=1"
de Sousa, J. M.Fillol-Salom, A.Penades, J. R.Rocha, E. P. C.2022-09-14doi:10.1101/2022.09.14.508007Cold Spring Harbor Laboratory Press2022-09-14
<![CDATA[
Transcriptional units form the elementary constraining building blocks of the bacterial chromosome
]]>
https://biorxiv.org/cgi/content/short/2022.09.16.507559v1?rss=1"
Bignaud, A.Cockram, C.Allemand, E.Mozziconacci, J.Espeli, O.Koszul, R.2022-09-16doi:10.1101/2022.09.16.507559Cold Spring Harbor Laboratory Press2022-09-16
<![CDATA[
Periplasmic coiled coil formed by assembly platform proteins PulL and PulM is critical for function of the Klebsiella type II secretion system
]]>
https://biorxiv.org/cgi/content/short/2022.09.21.508927v1?rss=1"
Li, Y.Santos Moreno, J.Francetic, O.2022-09-21doi:10.1101/2022.09.21.508927Cold Spring Harbor Laboratory Press2022-09-21
<![CDATA[
Queuosine modification of tRNA-Tyrosine elicits translational reprogramming and enhances growth of Vibrio cholerae with aminoglycosides.
]]>
https://biorxiv.org/cgi/content/short/2022.09.26.509455v1?rss=1"
Fruchard, L.Babosan, A.Carvalho, A.Lang, M.Li, B.Duchateau, M.Giai Gianetto, Q.Matondo, M.Bonhomme, F.Fabret, C.NAMY, O.de Crecy-Lagard, V.Mazel, D.Baharoglu, Z.2022-09-26doi:10.1101/2022.09.26.509455Cold Spring Harbor Laboratory Press2022-09-26
<![CDATA[
Caveolae govern plasma membrane mechanics to protect cells against EDIN B-induced transcellular tunnel formation and lethality from S. aureus septicaemia
]]>
https://biorxiv.org/cgi/content/short/2022.09.27.509635v1?rss=1"
Morel, C.Lemerle, E.Tsai, F.-C.Obadia, T.Srivastava, N.Marechal, M.Salles, A.Albert, M.Stefani, C.Lamaze, C.Vassilopoulos, S.Piel, M.Bassereau, P.Gonzalez-Rodriguez, D.Leduc, C.Lemichez, E.2022-09-28doi:10.1101/2022.09.27.509635Cold Spring Harbor Laboratory Press2022-09-28
<![CDATA[
The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells
]]>
https://biorxiv.org/cgi/content/short/2022.10.04.509876v1?rss=1"
Fernandez, I.Tofdal Dynesen, L.Coquin, Y.Pederzoli, R.Brun, D.Haouz, A.Gessain, A.Rey, F. A.Buseyne, F.Backovic, M.2022-10-05doi:10.1101/2022.10.04.509876Cold Spring Harbor Laboratory Press2022-10-05
<![CDATA[
Legionella para-effectors target chromatin and promote bacterial replication
]]>
https://biorxiv.org/cgi/content/short/2022.10.16.512414v1?rss=1"
Schator, D.Mondino, S.Berthelet, J.Di Silvestre, C.Ben Asssya, M.Rusniok, C.Rodreigues-Lima, F.Wehenkel, A. M.Buchrieser, C.Rolando, M.2022-10-16doi:10.1101/2022.10.16.512414Cold Spring Harbor Laboratory Press2022-10-16
<![CDATA[
Genomic epidemiology of Corynebacterium diphtheriae in New Caledonia
]]>
https://biorxiv.org/cgi/content/short/2022.10.23.512725v1?rss=1"
Tessier, E.Hennart, M.Badell-Ocando, E.Passet, V.Toubiana, J.Biron, A.Gourinat, A.-C.Merlet, A.Colot, J.Brisse, S.2022-10-24doi:10.1101/2022.10.23.512725Cold Spring Harbor Laboratory Press2022-10-24
<![CDATA[
Neutralization of zoonotic simian foamy viruses: genotype-specific epitopes within the receptor-binding domain
]]>
https://biorxiv.org/cgi/content/short/2022.11.06.515319v1?rss=1"
Dynesen, L. T.Fernandez, I.Coquin, Y.Delaplace, M.Montange, T.Njouom, R.Bilounga-Ndongo, C.Rey, F. A.Gessain, A.Backovic, M.Buseyne, F.2022-11-06doi:10.1101/2022.11.06.515319Cold Spring Harbor Laboratory Press2022-11-06
<![CDATA[
Resistance of Omicron subvariants BA.2.75.2, BA.4.6 and BQ.1.1 to neutralizing antibodies
]]>
https://biorxiv.org/cgi/content/short/2022.11.17.516888v1?rss=1"
Planas, D.Bruel, T.Staropoli, I.Guivel-Benhassine, F.Porrot, F.Maes, P.Grzelak, L.Prot, M.Mougari, S.Planchais, C.Puech, J.Saliba, M.Sahraoui, R.Femy, F.Morel, N.Dufloo, J.Sanjuan, R.Mouquet, H.Andre, E.Hocqueloux, L.Simon-Loriere, E.Veyer, D.Prazuck, T.Pere, H.Schwartz, O.2022-11-17doi:10.1101/2022.11.17.516888Cold Spring Harbor Laboratory Press2022-11-17
<![CDATA[
Environmental and genetic drivers of population differences in SARS-CoV-2 immune responses
]]>
https://biorxiv.org/cgi/content/short/2022.11.22.517073v1?rss=1"
Aquino, Y.Bisiaux, A.Li, Z.O'Neill, M.Mendoza-Revilla, J.Merkling, S. H.Kerner, G.Hasan, M.Libri, V.Bondet, V.Smith, N.de Cevins, C.Menager, M. M.Luca, F.Pique-Regi, R.Barba-Spaeth, G.Pietropaoli, S.Schwartz, O.Leroux-Roels, G.Lee, C.-K.Leung, K.Wu, J. T. K.Peiris, J. S. M.Bruzzone, R.Abel, L.Casanova, J.-L.Valkenburg, S. A.Duffy, D. A.Patin, E.Rotival, M.Quintana-Murci, L.2022-11-22doi:10.1101/2022.11.22.517073Cold Spring Harbor Laboratory Press2022-11-22
<![CDATA[
Rasputin/G3BP mediates o-nyong-nyong virus subversion of antiviral immunity in Anopheles coluzzii
]]>
https://biorxiv.org/cgi/content/short/2022.11.23.517724v1?rss=1"
Cottis, S.Blisnick, A.Mitri, C.Brito-Fravallo, E.Matondo, M.Failloux, A.-B.Vernick, K. D.2022-11-23doi:10.1101/2022.11.23.517724Cold Spring Harbor Laboratory Press2022-11-23
<![CDATA[
The cell wall lipoprotein CD1687 acts as a DNA binding protein during deoxycholate-induced biofilm formation in Clostridioides difficile
]]>
https://biorxiv.org/cgi/content/short/2022.11.29.518320v1?rss=1"
Auria, E.Hunault, L.ENGLAND, P.Monot, M.Pipoli Da Fonseca, J.Matondo, M.Duchateau, M.Tremblay, Y. D.Dupuy, B.2022-11-29doi:10.1101/2022.11.29.518320Cold Spring Harbor Laboratory Press2022-11-29
<![CDATA[
Mice Humanized for Major Histocompatibility Complex and Angiotensin-Converting Enzyme 2 with High Permissiveness to SARS-CoV-2 Omicron Replication
]]>
https://biorxiv.org/cgi/content/short/2022.12.01.518541v1?rss=1"
Le Chevalier, F.Authie, P.Chardenoux, S.Bourgine, M.Vesin, B.Cussigh, D.Sassier, Y.Fert, I.Noirat, A.Nemirov, K.ANNA, F.BERARD, M.Guinet, F.Hardy, D.Charneau, P.Lemonnier, F.Langa-Vives, F.MAJLESSI, L.2022-12-02doi:10.1101/2022.12.01.518541Cold Spring Harbor Laboratory Press2022-12-02
<![CDATA[
Gallocin A, an atypical two-peptide bacteriocin secreted by Streptococcus gallolyticus subsp. gallolyticus
]]>
https://biorxiv.org/cgi/content/short/2022.12.05.519244v1?rss=1"
Proutiere, A.du Merle, L.Garcia-Lopez, M.Leger, C.Voegele, A.Chenal, A.Harrington, A.Tal-Gan, Y.Cokelaer, T.Trieu-Cuot, P.Dramsi, S.2022-12-08doi:10.1101/2022.12.05.519244Cold Spring Harbor Laboratory Press2022-12-08
<![CDATA[
Tunneling nanotubes between neuronal and microglial cells allow bi-directional transfer of α-Synuclein and mitochondria
]]>
https://biorxiv.org/cgi/content/short/2022.12.13.519450v1?rss=1"
Chakraborty, R.Zurzolo, C.2022-12-14doi:10.1101/2022.12.13.519450Cold Spring Harbor Laboratory Press2022-12-14
<![CDATA[
B2LiVe, a label-free 1D-NMR method to quantify the binding of amphitropic peptides or proteins to membrane vesicles
]]>
https://biorxiv.org/cgi/content/short/2022.12.14.520471v1?rss=1"
Sadi, M.Carvalho, N.Vitorge, B.Ladant, D.Guijarro, J. I.CHENAL, A.2022-12-16doi:10.1101/2022.12.14.520471Cold Spring Harbor Laboratory Press2022-12-16
<![CDATA[
mapquik: Efficient low-divergence mapping of long reads in minimizer space
]]>
https://biorxiv.org/cgi/content/short/2022.12.23.521809v1?rss=1"
96% sensitivity and near-perfect specificity. On the human genome, mapquik achieves a 30x speed-up over the state-of-the-art tool minimap2, and on the maize genome, a 350x speed-up over minimap2, making mapquik the fastest mapper to date. These accelerations are enabled not only by minimizer-space seeding but also a novel heuristic [O](n) pseudo-chaining algorithm, which improves over the long-standing [O](n log n) bound. Minimizer-space computation builds the foundation for achieving real-time analysis of long-read sequencing data.
]]>Ekim, B.Sahlin, K.Medvedev, P.Berger, B.Chikhi, R.2022-12-23doi:10.1101/2022.12.23.521809Cold Spring Harbor Laboratory Press2022-12-23
<![CDATA[
Diversity and evolution of cerebellar folding in mammals
]]>
https://biorxiv.org/cgi/content/short/2022.12.30.522292v1?rss=1"
Heuer, K.Traut, N.de Sousa, A. A.Valk, S.Toro, R.2022-12-30doi:10.1101/2022.12.30.522292Cold Spring Harbor Laboratory Press2022-12-30
<![CDATA[
Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile
]]>
https://biorxiv.org/cgi/content/short/2023.01.02.522461v1?rss=1"
Auria, E.Deschamps, J.Briandet, R.Dupuy, B.2023-01-02doi:10.1101/2023.01.02.522461Cold Spring Harbor Laboratory Press2023-01-02
<![CDATA[
Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor
]]>
https://biorxiv.org/cgi/content/short/2023.01.03.522562v1?rss=1"
Li, Q.Nemecz, A.Ayme, G.Prevost, M. S.Pons, S.Dejean de la Batie, G.Barilone, N.Baachaoui, R.Maskos, U.Lafaye, P.Corringer, P.-J.2023-01-03doi:10.1101/2023.01.03.522562Cold Spring Harbor Laboratory Press2023-01-03
<![CDATA[
Corynebacterium of the diphtheriae complex in companion animals: clinical and microbiological characterization of 64 cases from France
]]>
https://biorxiv.org/cgi/content/short/2023.01.04.522820v1?rss=1"
Museux, K.Arcari, G.Rodrigo, G.Hennart, M.Badell-Ocando, E.Toubiana, J.Brisse, S.2023-01-05doi:10.1101/2023.01.04.522820Cold Spring Harbor Laboratory Press2023-01-05
<![CDATA[
APOBEC3F is the main source of editing identified during the 2022 outbreak of human monkeypox virus
]]>
https://biorxiv.org/cgi/content/short/2023.01.06.522979v1?rss=1"
A mutations occurring in the 5GpA context, indicative of APOBEC3 cytosine deaminase activity. By using a sensitive PCR (3D-PCR) method allowing differential amplification of AT-rich DNA, we demonstrate that G->A hypermutated MPXV genomes can be recovered experimentally from APOBEC3 transfection followed by MPXV infection. Here, among the 7 human APOBEC3 cytidine deaminases (A3A-A3C, A3DE, A3F-A3H), only APOBEC3F was capable of extensively deaminating cytidine residues in MPXV genomes. Hyperedited genomes were also recovered in ~42% of analyzed patients, indicating that editing is part of the natural cycle of MPXV infection. Moreover, we demonstrate that substantial repair of these mutations occurs. Upon selection, corrected G->A mutations escaping drift loss contribute to the MPXV evolution observed in the current epidemics. Thus, stochastic or transient overexpression of APOBEC3F gene exposes the MPXV genome to a broad spectrum of mutations that may be modeling the mutational landscape after multiple cycles of viral replication.
]]>Suspene, R.Raymond, K. A.Boutin, L.Guillier, S.Lemoine, F.Ferraris, O.Tournier, J.-N.Iseni, F.Simon-Loriere, E.Vartanian, J.-P.2023-01-07doi:10.1101/2023.01.06.522979Cold Spring Harbor Laboratory Press2023-01-07
<![CDATA[
N-Cadherin and alpha-catenin regulate formation of functional tunneling nanotubes
]]>
https://biorxiv.org/cgi/content/short/2023.01.10.523392v1?rss=1"
Pepe, A.Notario Manzano, R.Sartori-Rupp, A.Brou, C.Zurzolo, C.2023-01-10doi:10.1101/2023.01.10.523392Cold Spring Harbor Laboratory Press2023-01-10
<![CDATA[
Deadenylation rate is not a major determinant of RNA degradation in yeast
]]>
https://biorxiv.org/cgi/content/short/2023.01.16.524186v1?rss=1"
Audebert, L.Feuerbach, F.Decourty, L.Namane, A.Permal, E.Badis, G.Saveanu, C.2023-01-17doi:10.1101/2023.01.16.524186Cold Spring Harbor Laboratory Press2023-01-17
<![CDATA[
Nr5a2 is essential for morula development
]]>
https://biorxiv.org/cgi/content/short/2023.01.16.524255v1?rss=1"
Festuccia, N.Vandormael-Pournin, S.Chervova, A.Geiselmann, A.-M.Langa-Vives, F.Coux, R.-X.Gonzalez, I.Cohen-Tannoudji, M.Navarro, P.2023-01-18doi:10.1101/2023.01.16.524255Cold Spring Harbor Laboratory Press2023-01-18
<![CDATA[
decOM: Similarity-based microbial source tracking of ancient oral samples using k-mer-based methods
]]>
https://biorxiv.org/cgi/content/short/2023.01.26.525439v1?rss=1"
Duitama Gonzalez, C.Vicedomini, R.Lemane, T.Rascovan, N.Richard, H.Chikhi, R.2023-01-27doi:10.1101/2023.01.26.525439Cold Spring Harbor Laboratory Press2023-01-27
<![CDATA[
Streptococcus pneumoniae drives specific and lasting Natural Killer cell memory
]]>
https://biorxiv.org/cgi/content/short/2023.01.26.525815v1?rss=1"
Camarasa, T. M. N.Torne, J.Chevalier, C.Rasid, O.Hamon, M. A.2023-01-27doi:10.1101/2023.01.26.525815Cold Spring Harbor Laboratory Press2023-01-27
<![CDATA[
Extracellular vesicles production regulates fluconazole resistance in Cryptococcus neoformans
]]>
https://biorxiv.org/cgi/content/short/2023.01.30.526212v1?rss=1"
Rizzo, J.Trottier, A.Moyrand, F.Coppee, J.-Y.Maufrais, C.Zimbres, A. C. G.Dang, T. T. V.Alanio, A.Desnos-Ollivier, M.Mouyna, I.PEHAU-ARNAUDET, G.Commere, P.-H.Novault, S.Ene, I. V.Nimrichter, L.Rodrigues, M.Janbon, G.2023-01-30doi:10.1101/2023.01.30.526212Cold Spring Harbor Laboratory Press2023-01-30
<![CDATA[
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation.
]]>
https://biorxiv.org/cgi/content/short/2023.02.01.526586v1?rss=1"
Martinez, M.Petit, J.Leyva, A.Sogues Castrejon, A.Megrian, D.Rodriguez, A.Gaday, Q.Ben Assaya, M.Portela, M. M.Haouz, A.Ducret, A.Grangeasse, C.Alzari, P. M.Duran, R.Wehenkel, A. M.2023-02-01doi:10.1101/2023.02.01.526586Cold Spring Harbor Laboratory Press2023-02-01
<![CDATA[
Assessing vector competence of mosquitoes from northeastern France to West Nile virus and Usutu virus
]]>
https://biorxiv.org/cgi/content/short/2023.02.07.527438v1?rss=1"
Martinet, J.-P.Bohers, C.Vazeille, M.Ferte, H.Mousson, L.Mathieu, B.Depaquit, J.Failloux, A.-B.2023-02-07doi:10.1101/2023.02.07.527438Cold Spring Harbor Laboratory Press2023-02-07
<![CDATA[
CellWalker: A user-friendly and modular computational pipeline for morphological analysis of microscopy images
]]>
https://biorxiv.org/cgi/content/short/2023.02.13.526957v1?rss=1"
Khare, H.Dongo Mendoza, N.Zurzolo, C.2023-02-15doi:10.1101/2023.02.13.526957Cold Spring Harbor Laboratory Press2023-02-15
<![CDATA[
Escherichia coli aggregates mediated by native or synthetic adhesins exhibit both core and adhesin-specific transcriptional responses
]]>
https://biorxiv.org/cgi/content/short/2023.02.14.528454v1?rss=1"
Chekli, Y.Stevick, R. J.Kornobis, E.Briolat, V.Ghigo, J.-M.BELOIN, C.2023-02-14doi:10.1101/2023.02.14.528454Cold Spring Harbor Laboratory Press2023-02-14
<![CDATA[
The oncogenic role of Streptococcus gallolyticus subsp. gallolyticus is linked to activation of multiple cancer-related signaling pathways
]]>
https://biorxiv.org/cgi/content/short/2023.02.17.528913v1?rss=1"
Pasquereau-Kotula, E.Nigro, G.Dingli, F.Loew, D.Poullet, P.Xu, Y.Kopetz, S.Davis, J.Peduto, L.Robbe-Masselot, C.Sansonetti, P.Trieu-Cuot, P.Dramsi, S.2023-02-18doi:10.1101/2023.02.17.528913Cold Spring Harbor Laboratory Press2023-02-18
<![CDATA[
A global Corynebacterium diphtheriae genomic framework sheds light on current diphtheria reemergence
]]>
https://biorxiv.org/cgi/content/short/2023.02.20.529124v1?rss=1"
Hennart, M.Crestani, C.Bridel, S.Armatys, N.Bremont, S.Carmi-Leroy, A.Landier, A.Passet, V.Fonteneau, L.Vaux, S.Toubiana, J.Badell-Ocando, E.Brisse, S.2023-02-20doi:10.1101/2023.02.20.529124Cold Spring Harbor Laboratory Press2023-02-20
<![CDATA[
FLAgellum Member 8 modulates extravasation and extravascular distribution of African trypanosomes.
]]>
https://biorxiv.org/cgi/content/short/2023.02.20.529185v1?rss=1"
Alvarez, E. C.Ngoune, J. M. T.Cooper, A.Travaille, C.Crouzols, A.MacLeod, A.Rotureau, B.2023-02-20doi:10.1101/2023.02.20.529185Cold Spring Harbor Laboratory Press2023-02-20
<![CDATA[
High resolution cryo-EM and crystallographic snapshots of the large actinobacterial 2-oxoglutarate dehydrogenase: an all-in-one fusion with unique properties
]]>
https://biorxiv.org/cgi/content/short/2023.02.23.529587v1?rss=1"
Yang, L.Wagner, T.Mechaly, A.Boyko, A.Bruch, E. M.Megrian, D.Gubellini, F.Alzari, P. M.Bellinzoni, M.2023-02-23doi:10.1101/2023.02.23.529587Cold Spring Harbor Laboratory Press2023-02-23
<![CDATA[
BioConvert: a comprehensive format converter for life sciences
]]>
https://biorxiv.org/cgi/content/short/2023.03.13.532455v1?rss=1"
Caro, H.Dollin, S.Brancotte, B.Desvillechabrol, D.Dufresne, Y.Li, B.Biton, A.Kornobis, E.Lemoine, F.Maillet, N.PERRIN, A.Traut, N.Neron, B.Cokelaer, T.2023-03-15doi:10.1101/2023.03.13.532455Cold Spring Harbor Laboratory Press2023-03-15
<![CDATA[
Role of the Escherichia coli ubiquinone-synthesizing UbiUVT pathway in adaptation to changing respiratory conditions
]]>
https://biorxiv.org/cgi/content/short/2023.03.15.532739v1?rss=1"
Arias-Cartin, R.Kazemzadeh Ferizhendi, K.Sechet, E.Pelosi, L.Loeuillet, C.Pierrel, F.Barras, F.Bouveret, E.2023-03-15doi:10.1101/2023.03.15.532739Cold Spring Harbor Laboratory Press2023-03-15
<![CDATA[
Interactions of the Protein Tyrosine Phosphatase PTPN3 with Viral and Cellular Partners through its PDZ Domain: Insights into Structural Determinants and Phosphatase Activity
]]>
https://biorxiv.org/cgi/content/short/2023.03.23.533931v1?rss=1"
Genera, M.Colcombet-Cazenave, B.Croitoru, A.Raynal, B.Mechaly, A.Caillet, J.Haouz, A.Wolff, N.Caillet-Saguy, C.2023-03-24doi:10.1101/2023.03.23.533931Cold Spring Harbor Laboratory Press2023-03-24
<![CDATA[
Collaborative Cross strains reveal that Irf3 deficiency results in uncontrolled Zika virus replication in vitro but is insufficient to induce disease susceptibility in mice.
]]>
https://biorxiv.org/cgi/content/short/2023.03.27.534491v1?rss=1"
Bourdon, M.MANET, C.Conquet, L.Ramauge-Parra, C.KORNOBIS, E.Bonnefoy, E.Montagutelli, X.2023-03-30doi:10.1101/2023.03.27.534491Cold Spring Harbor Laboratory Press2023-03-30
<![CDATA[
ChoruMM: a versatile multi-components mixed model for bacterial-GWAS
]]>
https://biorxiv.org/cgi/content/short/2023.03.28.534531v1?rss=1"
Frouin, A.Laporte, F.Hafner, L.Maury, M.McCaw, Z. R.Henches, L.Julienne, H.Chikhi, R.Lecuit, M.Aschard, H.2023-03-29doi:10.1101/2023.03.28.534531Cold Spring Harbor Laboratory Press2023-03-29
<![CDATA[
Genomic characterization of the antiviral arsenal of Actinobacteria
]]>
https://biorxiv.org/cgi/content/short/2023.03.30.534874v1?rss=1"
Georjon, H.Tesson, F.Shomar, H.Bernheim, A.2023-03-30doi:10.1101/2023.03.30.534874Cold Spring Harbor Laboratory Press2023-03-30
<![CDATA[
Dynamic microfluidic single-cell screening identifies pheno-tuning compounds to potentiate tuberculosis therapy
]]>
https://biorxiv.org/cgi/content/short/2023.03.31.535085v1?rss=1"
Mistretta, M.Cimino, M.Campagne, P.Volant, S.Kornobis, E.Hebert, O.Rochais, C.Dallemagne, P.Lecoutey, C.Tisnerat, C.Lepailleur, A.Ayotte, Y.LaPlante, S. R.Gangneux, N.Zahorszka, M.Kordulakova, J.Vichier-Guerre, S.Bonhomme, F.Pokorny, L.Albert, M.Tinevez, J.-Y.Manina, G.2023-04-01doi:10.1101/2023.03.31.535085Cold Spring Harbor Laboratory Press2023-04-01
<![CDATA[
Latent evolution of biofilm formation depends on life-history and genetic background
]]>
https://biorxiv.org/cgi/content/short/2023.04.06.535679v1?rss=1"
Nucci, A.Rocha, E. P. C.Rendueles, O.2023-04-06doi:10.1101/2023.04.06.535679Cold Spring Harbor Laboratory Press2023-04-06
<![CDATA[
Coexistence of state, choice, and sensory integration coding in barrel cortex LII/III
]]>
https://biorxiv.org/cgi/content/short/2023.04.10.536289v1?rss=1"
Garderes, P.-M.Ganea, D. A.Le Gal, S.Rousseau, C. V.Mamane, A.Haiss, F.2023-04-11doi:10.1101/2023.04.10.536289Cold Spring Harbor Laboratory Press2023-04-11
<![CDATA[
Capsules and their traits shape phage susceptibility and plasmid conjugation efficiency
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https://biorxiv.org/cgi/content/short/2023.04.12.536574v1?rss=1"
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]]>Haudiquet, M.Nucci, A.Le Bris, J.Bonnin, R. A.Domingo-Calap, P.Rendueles, O.Rocha, E. P. C.2023-04-12doi:10.1101/2023.04.12.536574Cold Spring Harbor Laboratory Press2023-04-12
<![CDATA[
Anti-diarrheal drug loperamide induces dysbiosis in zebrafish microbiota via bacterial inhibition
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https://biorxiv.org/cgi/content/short/2023.04.18.537295v1?rss=1"
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org.highwire.dtl.DTLVardef@11c5492org.highwire.dtl.DTLVardef@f44f40org.highwire.dtl.DTLVardef@17eff8corg.highwire.dtl.DTLVardef@bb691a_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>STEVICK, R. J.BEDU, S.DRAY, N.GHIGO, J.-M.PEREZ-PASCUAL, D.2023-04-18doi:10.1101/2023.04.18.537295Cold Spring Harbor Laboratory Press2023-04-18
<![CDATA[
Differentiating Agonists and Competitive Antagonists of the Serotonin Type 3A (5-HT3A) Receptor
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https://biorxiv.org/cgi/content/short/2023.05.15.540789v1?rss=1"
Davolio, A. J.Jankowski, W. J.Varnai, C.Irwin, B. W. J.Payne, M. C.Chau, P. L.2023-05-15doi:10.1101/2023.05.15.540789Cold Spring Harbor Laboratory Press2023-05-15
<![CDATA[
Transcriptome profiling of human colonic cells exposed to the gut pathobiont Streptococcus gallolyticus subsp. gallolyticus.
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https://biorxiv.org/cgi/content/short/2023.05.16.540927v1?rss=1"
Pasquereau-Kotula, E.du Merle, L.Sismeiro, O.Pietrosemoli, N.Varet, H.Legendre, R.Trieu-Cuot, P.Dramsi, S.2023-05-16doi:10.1101/2023.05.16.540927Cold Spring Harbor Laboratory Press2023-05-16
<![CDATA[
Epithelial cells maintain memory of prior infection with Streptococcus pneumoniae through di-methylation of histone H3
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https://biorxiv.org/cgi/content/short/2023.05.19.541441v1?rss=1"
Chevalier, C.Chica, C.Matheau, J.Connor, M. G.Pain, A.Hamon, M. A.2023-05-19doi:10.1101/2023.05.19.541441Cold Spring Harbor Laboratory Press2023-05-19
<![CDATA[
Shigella generates distinct IAM subpopulations during epithelial cell invasion to promote efficient intracellular niche formation
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https://biorxiv.org/cgi/content/short/2023.05.22.540987v1?rss=1"
Sanchez, L.Connor, M. G.Hamon, M. A.Valenzuela, C.Enninga, J.2023-05-22doi:10.1101/2023.05.22.540987Cold Spring Harbor Laboratory Press2023-05-22
<![CDATA[
Dual proteomic signature of immune cells and Yersinia pestis upon blood infection
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https://biorxiv.org/cgi/content/short/2023.06.19.545537v1?rss=1"
Le-Bury, P.Douche, T.Giai Gianetto, Q.Matondo, M.Pizarro-Cerda, J.Dussurget, O.2023-06-22doi:10.1101/2023.06.19.545537Cold Spring Harbor Laboratory Press2023-06-22
<![CDATA[
Chance favors the prepared genomes: horizontal transfer shapes the emergence of antibiotic resistance mutations in core genes.
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https://biorxiv.org/cgi/content/short/2023.06.20.545734v1?rss=1"
Coluzzi, C.Guillemet, M.Mazzamurro, F.Touchon, M.Godfroid, M.Achaz, G.Glaser, P.Rocha, E. P. C.2023-06-22doi:10.1101/2023.06.20.545734Cold Spring Harbor Laboratory Press2023-06-22
<![CDATA[
PI3K/AKT signalling orchestrates ICM maturation and proper epiblast and primitive endoderm specification
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https://biorxiv.org/cgi/content/short/2023.06.21.545867v1?rss=1"
Geiselmann, A.Micouin, A.Vandormael-Pournin, S.Laville, V.Mella, S.Navarro, P.Cohen-Tannoudji, M.2023-06-21doi:10.1101/2023.06.21.545867Cold Spring Harbor Laboratory Press2023-06-21
<![CDATA[
First genome-based characterization of Listeria monocytogenes in Costa Rica
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https://biorxiv.org/cgi/content/short/2023.06.23.543262v1?rss=1"
Giralt-Zuniga, M.Redondo-Solano, M.Moura, A.Tessaud-Rita, N.Bracq-Dieye, H.Vales, G.Thouvenot, P.Leclercq, A.Chaves-Ulate, C.Nunez-Montero, K.Guillen-Watson, R.Rivas-Solano, O.Chanto-Chacon, G.Duarte-Martinez, F.Soto-Blanco, V.Pizarro-Cerda, J.Lecuit, M.2023-06-23doi:10.1101/2023.06.23.543262Cold Spring Harbor Laboratory Press2023-06-23
<![CDATA[
Multi-trait GWAS for diverse ancestries: Mapping the knowledge gap
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https://biorxiv.org/cgi/content/short/2023.06.23.546248v1?rss=1"
Troubat, L.Fettahoglu, D.Aschard, H.Julienne, H.2023-06-25doi:10.1101/2023.06.23.546248Cold Spring Harbor Laboratory Press2023-06-25
<![CDATA[
Bridges instead of boats? The Mla system of diderm Firmicute Veillonella parvula reveals an ancestral transenvelope core of phospholipid trafficking
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https://biorxiv.org/cgi/content/short/2023.06.30.547184v1?rss=1"
BELOIN, C.Grasekamp, K. P.Beaud, B.Taib, N.Audrain, B.Bardiaux, B.Rossez, Y.IZADI-PRUNEYRE, N.Lejeune, M.Trivelli, X.Chouit, Z.Guerardel, Y.GHIGO, J.-M.Gribaldo, S.2023-06-30doi:10.1101/2023.06.30.547184Cold Spring Harbor Laboratory Press2023-06-30
<![CDATA[
Emergence of novel non-aggregative variants under negative frequency-dependent selection in Klebsiella variicola
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https://biorxiv.org/cgi/content/short/2023.07.10.548335v1?rss=1"
Nucci, A.Janaszkiewicz, J.Rocha, E. P. C.Rendueles, O.2023-07-10doi:10.1101/2023.07.10.548335Cold Spring Harbor Laboratory Press2023-07-10
<![CDATA[
Tur1 regulates alternative TSS usage in Cryptococcus
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https://biorxiv.org/cgi/content/short/2023.07.18.549460v1?rss=1"
Dang, T. T. V.Maufrais, C.Colin, J.Moyrand, F.Mouyna, I.Coppee, J.-Y.Onyishi, C. U.Lipecka, J.Guerrera, I. C.May, R. C.Janbon, G.2023-07-18doi:10.1101/2023.07.18.549460Cold Spring Harbor Laboratory Press2023-07-18
<![CDATA[
RNA polymerase III is involved in regulating Plasmodium falciparum virulence
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https://biorxiv.org/cgi/content/short/2023.07.18.549525v1?rss=1"
Diffendall, G. M.Claes, A.Barcons-Simon, A.Nyarko, P.Dingli, F.Loew, D.Claessens, A.Scherf, A.2023-07-20doi:10.1101/2023.07.18.549525Cold Spring Harbor Laboratory Press2023-07-20
<![CDATA[
Xrn1 biochemically associates to the eisosome after the post diauxic shift in yeast
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https://biorxiv.org/cgi/content/short/2023.07.19.549689v1?rss=1"
Courtin, B.Namane, A.Gomard, M.Meyer, L.Jacquier, A.Fromont-Racine, M.2023-07-19doi:10.1101/2023.07.19.549689Cold Spring Harbor Laboratory Press2023-07-19
<![CDATA[
An oxadiazole-based compound potentiates anti- tuberculosis treatment by increasing host resistance via zinc poisoning
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https://biorxiv.org/cgi/content/short/2023.07.21.549986v1?rss=1"
Maure, A.Lawaree, E.Fiorentino, F.Pawlik, A.Gona, S.Giraud-Gatineau, A.Eldridge, M. J. G.Danckaert, A.Hardy, D.Frigui, W.Keck, C.Aulner, N.Mai, A.Hamon, M.Barreiro, L. B.Brodin, P.Brosch, R.Rotili, D.Tailleux, L.2023-07-21doi:10.1101/2023.07.21.549986Cold Spring Harbor Laboratory Press2023-07-21
<![CDATA[
MiniBAR/KIAA0355 is a dual Rac and Rab effector required for ciliogenesis
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https://biorxiv.org/cgi/content/short/2023.07.24.550339v1?rss=1"
Shaughnessy, R.Serres, M.Escot, S.Hammich, H.Cuvelier, F.Salles, A.Rocancourt, M.Verdon, Q.Gaffuri, A.-L.Sourigues, Y.Malherbe, G.Velikovsky, L.Chardon, F.Tinevez, J.-Y.Callebaut, I.Formstecher, E.Houdusse, A.David, N.Pylypenko, O.Echard, A.2023-07-24doi:10.1101/2023.07.24.550339Cold Spring Harbor Laboratory Press2023-07-24
<![CDATA[
Beyond 40 fluorescent probes for deep phenotyping of blood mononuclear cells, using spectral technology.
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https://biorxiv.org/cgi/content/short/2023.07.27.550830v1?rss=1"
Schmutz, S.Commere, P.-H.Montcuquet, N.Cumano, A.Ait-Mansour, C.Novault, S.Hasan, M.2023-07-27doi:10.1101/2023.07.27.550830Cold Spring Harbor Laboratory Press2023-07-27
<![CDATA[
Prodomain-driven enzyme dimerization, a potent pH-dependent autoinhibition mechanism to control Plasmodium Sub1 subtilisin-like activity prior to prime merozoite egress
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https://biorxiv.org/cgi/content/short/2023.07.31.551325v1?rss=1"
Barale, J.-C.Mariano, M.Anthony, B.Sebastien, B.Bertrand, R.Ahmed, H.Pedro, A. M.2023-08-01doi:10.1101/2023.07.31.551325Cold Spring Harbor Laboratory Press2023-08-01
<![CDATA[
Metabolic reprogramming during Candida albicans planktonic-biofilm transition is modulated by the ZCF15 and ZCF26 paralogs
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https://biorxiv.org/cgi/content/short/2023.08.03.551767v1?rss=1"
Rai, L. S.Chauvel, M.Sanchez, H.van Wijlick, L.Maufrais, C.Cokelaer, T.Sertour, N.Legrand, M.Andes, D. R.Bachellier-Bassi, S.d'Enfert, C.2023-08-03doi:10.1101/2023.08.03.551767Cold Spring Harbor Laboratory Press2023-08-03
<![CDATA[
Phage-plasmids promote genetic exchanges between phages and plasmids and create novel ones.
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https://biorxiv.org/cgi/content/short/2023.08.08.552325v1?rss=1"
Pfeifer, E.Rocha, E. P. C.2023-08-11doi:10.1101/2023.08.08.552325Cold Spring Harbor Laboratory Press2023-08-11
<![CDATA[
Novel roles for the LRRC56 protein, an IFT cargo protein, in docking of dynein arms in Trypanosoma brucei
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https://biorxiv.org/cgi/content/short/2023.08.09.552631v1?rss=1"
BONNEFOY, S.Alves, A. A.Bertiaux, E.Bastin, P.2023-08-09doi:10.1101/2023.08.09.552631Cold Spring Harbor Laboratory Press2023-08-09
<![CDATA[
Three Accessory Gene Clusters Drive Host-Adaptation in Group B Streptococcus
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https://biorxiv.org/cgi/content/short/2023.08.10.552778v1?rss=1"
Crestani, C.Forde, T. L.Bell, J.Lycett, S. J.Oliveira, L. M.Pinto, T. C.Cobo-Angel, C. G.Ceballos-Marquez, A.Phuoc, N. N.Sirimanapong, W.Chen, S. L.Jamrozy, D.Bentley, S. D.Fontaine, M.Zadoks, R. N.2023-08-13doi:10.1101/2023.08.10.552778Cold Spring Harbor Laboratory Press2023-08-13
<![CDATA[
MYC and MAX drive the reactivation of the genome after mitosis
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https://biorxiv.org/cgi/content/short/2023.08.13.553120v1?rss=1"
Gonzalez, I.Chervova, A.Escoll Guerrero, P.Altamirano-Pacheco, L.Mueller, F.Dubois, A.Navarro, P.2023-08-14doi:10.1101/2023.08.13.553120Cold Spring Harbor Laboratory Press2023-08-14
<![CDATA[
Interplay between Pitx2 and Pax7 temporally governs specification of extraocular muscle progenitors
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https://biorxiv.org/cgi/content/short/2023.08.24.554745v1?rss=1"
Kuriki, M.Comai, G.Tajbakhsh, S.2023-08-25doi:10.1101/2023.08.24.554745Cold Spring Harbor Laboratory Press2023-08-25
<![CDATA[
A short sequence in the tail of SARS-CoV-2 envelope protein controls accessibility of its PDZ Binding Motif to the cytoplasm.
]]>
https://biorxiv.org/cgi/content/short/2023.08.29.555304v1?rss=1"
Neitthoffer, B.Alvarez, F.Larrous, F.Caillet-Saguy, C.Etienne-Manneville, S.Boeda, B.2023-08-29doi:10.1101/2023.08.29.555304Cold Spring Harbor Laboratory Press2023-08-29
<![CDATA[
Stumpy forms are the predominant transmissible forms of Trypanosoma brucei.
]]>
https://biorxiv.org/cgi/content/short/2023.08.30.555461v1?rss=1"
Ngoune, J. M. T.SHARMA, P.Crouzols, A.Rotureau, B.2023-08-30doi:10.1101/2023.08.30.555461Cold Spring Harbor Laboratory Press2023-08-30
<![CDATA[
Belt and braces: two escape ways to maintain the cassette reservoir of large chromosomal integrons
]]>
https://biorxiv.org/cgi/content/short/2023.08.31.555669v1?rss=1"
Richard, E.Darracq, B.Littner, E.Millot, G.Conte, V.Cokelaer, T.Engelstaedter, J.Rocha, E.Mazel, D.Loot, C.2023-09-01doi:10.1101/2023.08.31.555669Cold Spring Harbor Laboratory Press2023-09-01
<![CDATA[
High fusion and cytopathy of SARS-CoV-2 variant B.1.640.1
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https://biorxiv.org/cgi/content/short/2023.09.06.556548v1?rss=1"
Bolland, W.Michel, V.Planas, D.Hubert, M.Guivel-Benhassine, F.Porrot, F.Staropoli, I.N'Debi, M.Rodriguez, C.Fourati, S.Prot, M.Planchais, C.Hocqueloux, L.Simon-Loriere, E.Mouquet, H.Prazuck, T.Pawlotsky, J.-M.Bruel, T.Schwartz, O.Buchrieser, J.2023-09-11doi:10.1101/2023.09.06.556548Cold Spring Harbor Laboratory Press2023-09-11
<![CDATA[
Tick-borne flavivirus NS5 antagonizes interferon signaling by inhibiting the catalytic activity of TYK2
]]>
https://biorxiv.org/cgi/content/short/2023.09.07.556670v1?rss=1"
Gracias, S.Chazal, M.Decombe, A.Unterfinger, Y.Sogues, A.Pruvost, L.Robert, V.Lacour, S.Lemasson, M.Sourisseau, M.Li, Z.Richardson, J.Decroly, E.Pellegrini, S.Caval, V.Jouvenet, N.2023-09-07doi:10.1101/2023.09.07.556670Cold Spring Harbor Laboratory Press2023-09-07
<![CDATA[
Viperin immunity evolved across the tree of life through serial innovations on a conserved scaffold
]]>
https://biorxiv.org/cgi/content/short/2023.09.13.557418v1?rss=1"
Shomar, H.Georjon, H.Feng, Y.Olympio, B.Tesson, F.Cury, J.Wu, F.Bernheim, A.2023-09-13doi:10.1101/2023.09.13.557418Cold Spring Harbor Laboratory Press2023-09-13
<![CDATA[
The multiplicity of Thioredoxin systems meets the specific needs of Clostridia
]]>
https://biorxiv.org/cgi/content/short/2023.09.14.557728v1?rss=1"
Anjou, C.Lotoux, A.Zhukova, A.Royer, M.Caulat, L. C.Capuzzo, E.Morvan, C.Martin-Verstraete, I.2023-09-14doi:10.1101/2023.09.14.557728Cold Spring Harbor Laboratory Press2023-09-14
<![CDATA[
The TcdE holin drives toxin secretion and virulence in Clostridioides difficile.
]]>
https://biorxiv.org/cgi/content/short/2023.09.16.558055v1?rss=1"
DiBenedetto, N. V.Oberkampf, M.Cersosimo, L.Yeliseyev, V.Bry, L.Peltier, J.Dupuy, B.2023-09-16doi:10.1101/2023.09.16.558055Cold Spring Harbor Laboratory Press2023-09-16
<![CDATA[
A multivariate outcome test of covariance
]]>
https://biorxiv.org/cgi/content/short/2023.09.20.558234v1?rss=1"
Boetto, C.Frouin, A.Henches, L.Auvergne, A.Suzuki, Y.Patin, E.Bredon, M.Chiu, A. M.Milieu Interieur Consortium,Sankararaman, S.Zaitlen, N.Kennedy, S.Quintana-Murci, L.Duffy, D.Sokol, H.Aschard, H.2023-09-22doi:10.1101/2023.09.20.558234Cold Spring Harbor Laboratory Press2023-09-22
<![CDATA[
A monoclonal antibody collection for C. difficile typing
]]>
https://biorxiv.org/cgi/content/short/2023.09.21.557191v1?rss=1"
Hunault, L.England, P.Barbut, F.Iannascoli, B.Godon, O.Dejardin, F.Thomas, C.Dupuy, B.Guo, C.Macdonald, L.Gorochov, G.Sterlin, D.Bruhns, P.2023-09-21doi:10.1101/2023.09.21.557191Cold Spring Harbor Laboratory Press2023-09-21
<![CDATA[
Mapping the molecular motions of 5-HT3 serotonin-gated channel by Voltage-Clamp Fluorometry
]]>
https://biorxiv.org/cgi/content/short/2023.09.28.559960v1?rss=1"
Peverini, L.Shi, S.Medjebeur, K.Corringer, P.-J.2023-09-28doi:10.1101/2023.09.28.559960Cold Spring Harbor Laboratory Press2023-09-28
<![CDATA[
Inhibition of the macrophage demethylase LSD1 reverses Leishmania amazonensis-induced transcriptomic changes and causes a decrease in parasite load
]]>
https://biorxiv.org/cgi/content/short/2023.09.29.560133v1?rss=1"
Gutierrez-Sanchez, M.Zhang, S.Gharsallah, C.Lamotte, S.Varet, H.Legendre, R.Dingli, F.Loew, D.Rotili, D.Valente, S.Mai, A.Loiseau, P.Pomel, S.Jung, M.Lecoeur, H.Prina, E.Spaeth, G. F.2023-09-29doi:10.1101/2023.09.29.560133Cold Spring Harbor Laboratory Press2023-09-29
<![CDATA[
Using a micro-device with a deformable ceiling to probe stiffness heterogeneities within 3D cell aggregates
]]>
https://biorxiv.org/cgi/content/short/2023.10.03.559477v1?rss=1"
Jain, S.Belkadi, H.Michaut, A.Sart, S.Gros, J.Genet, M.Baroud, C. N.2023-10-05doi:10.1101/2023.10.03.559477Cold Spring Harbor Laboratory Press2023-10-05
<![CDATA[
A polarized cell system amenable to subcellular resolution imaging of influenza virus infection
]]>
https://biorxiv.org/cgi/content/short/2023.10.03.560780v1?rss=1"
Naffakh, N.Brault, J.-B.Thouvenot, C.Cannata-Serio, M.Paisant, S.Fernandez, J.Geny, D.Danglot, L.Mallet, A.2023-10-04doi:10.1101/2023.10.03.560780Cold Spring Harbor Laboratory Press2023-10-04
<![CDATA[
Anchoring of parasitic plasmids to inactive regions of eukaryotic chromosomes through nucleosome signal
]]>
https://biorxiv.org/cgi/content/short/2023.10.04.558402v1?rss=1"
Girard, F.Even, A.Thierry, A.Ruault, M.Meneu, L.Adiba, S.Taddei, A.Koszul, R.Cournac, A.2023-10-04doi:10.1101/2023.10.04.558402Cold Spring Harbor Laboratory Press2023-10-04
<![CDATA[
Tunneling nanotubes enable intercellular transfer in zebrafish embryos
]]>
https://biorxiv.org/cgi/content/short/2023.10.12.562005v1?rss=1"
Korenkova, O.Liu, S.Prlesi, I.Pepe, A.Albadri, S.Del Bene, F.Zurzolo, C.2023-10-12doi:10.1101/2023.10.12.562005Cold Spring Harbor Laboratory Press2023-10-12
<![CDATA[
TALEN-induced contraction of CTG trinucleotide repeats in myotonic dystrophy type 1 cells
]]>
https://biorxiv.org/cgi/content/short/2023.10.14.562330v1?rss=1"
Betemps, L.Descorps-Declere, S.Frenoy, O.Poggi, L.Mosbach, V.Tome, S.Viterbo, D.Klein, A.Ma, L.Cokelaer, T.Monot, M.Dumas, B.Gourdon, G.Furling, D.Richard, G.-F.2023-10-18doi:10.1101/2023.10.14.562330Cold Spring Harbor Laboratory Press2023-10-18
<![CDATA[
Accurate model and ensemble refinement using cryo-electron microscopy maps and Bayesian inference
]]>
https://biorxiv.org/cgi/content/short/2023.10.18.562710v1?rss=1"
Hoff, S. E.Thomasen, F. E.Lindorff-Larsen, K.Bonomi, M.2023-10-19doi:10.1101/2023.10.18.562710Cold Spring Harbor Laboratory Press2023-10-19
<![CDATA[
Linking the genetic structure of neuroanatomical phenotypes with psychiatric disorders
]]>
https://biorxiv.org/cgi/content/short/2023.11.01.564329v1?rss=1"
Auvergne, A.Traut, N.Henches, L.Troubat, L.Frouin, A.Boetto, C.Kazem, S.Julienne, H.Toro, R.Aschard, h.2023-11-02doi:10.1101/2023.11.01.564329Cold Spring Harbor Laboratory Press2023-11-02
<![CDATA[
Unveiling the Hidden Viromes Across the Animal Tree of Life: Insights from a Taxonomic Classification Pipeline Applied to Invertebrates of 31 Metazoan Phyla
]]>
https://biorxiv.org/cgi/content/short/2023.11.03.565523v1?rss=1"
Alfonso, P.Butkovic, A.Fernandez, R.Riesgo, A.Elena, S. F.2023-11-06doi:10.1101/2023.11.03.565523Cold Spring Harbor Laboratory Press2023-11-06
<![CDATA[
Challenges in the Biotechnological Implementation of Oral RNA Interference as an Antiviral Strategy in Aedes aegypti
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https://biorxiv.org/cgi/content/short/2023.11.05.565667v1?rss=1"
Romoli, O.Henrion-Lacritick, A.Blanc, H.Frangeul, L.Saleh, M. C.2023-11-05doi:10.1101/2023.11.05.565667Cold Spring Harbor Laboratory Press2023-11-05
<![CDATA[
Intragenomic conflicts with plasmids and chromosomal mobile genetic elements drive the evolution of natural transformation within species
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https://biorxiv.org/cgi/content/short/2023.11.06.565790v1?rss=1"
Mazzamurro, F.Chirakadavil, J. B.Durieux, I.Poire, L.Plantade, J.Ginevra, C.Jarraud, S.Wilharm, G.Charpentier, X.Rocha, E. P. C.2023-11-06doi:10.1101/2023.11.06.565790Cold Spring Harbor Laboratory Press2023-11-06
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Viral infection disrupts intestinal homeostasis via Sting-dependent NF-kB signaling
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https://biorxiv.org/cgi/content/short/2023.11.16.567400v1?rss=1"
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]]>Nigg, J. C.Blanc, H.Frangeul, L.Mongelli, V.Godron, X.Bardin, A. J.Saleh, M.-C.2023-11-16doi:10.1101/2023.11.16.567400Cold Spring Harbor Laboratory Press2023-11-16
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An unusual two-strain cholera outbreak in Lebanon, 2022-2023: a genomic epidemiology study
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https://biorxiv.org/cgi/content/short/2023.11.29.569232v1?rss=1"
Abou Fayad, A.Rafei, R.Njamkepo, E.Ezzeddine, J.Hussein, H.Sinno, S.Gerges, J.-R.Barada, S.Sleiman, A.Assi, M.Baakliny, M.Hamedeh, L.Mahfouz, R.Dabboussi, F.Feghali, R.Mohsen, Z.Rady, A.Ghosn, N.Abiad, F.Abubakar, A.Barakat, A.Wauquier, N.Quilici, M.-L.Weill, F.-X.Hamze, M.Matar, G. M.2023-11-30doi:10.1101/2023.11.29.569232Cold Spring Harbor Laboratory Press2023-11-30
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The Cryptocococcus extracellular vesicle transcriptome
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https://biorxiv.org/cgi/content/short/2023.12.08.570810v1?rss=1"
Taheraly, A.Maufrais, C.Moyrand, F.Coppee, J.-Y.Colin, J.Janbon, G.2023-12-08doi:10.1101/2023.12.08.570810Cold Spring Harbor Laboratory Press2023-12-08
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Role of two modules controlling the interaction between SKAP1 and SRC kinasesComparison with SKAP2 architecture and consequences for evolution
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https://biorxiv.org/cgi/content/short/2023.12.11.571115v1?rss=1"
Levillayer, L.Brighelli, C.Demeret, C.Sakuntabhai, A.Bureau, J.-F.2023-12-11doi:10.1101/2023.12.11.571115Cold Spring Harbor Laboratory Press2023-12-11
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Single-cell RNAseq reveals the pro-regenerative role of senescent FAPs in muscle regeneration
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https://biorxiv.org/cgi/content/short/2023.12.12.571148v1?rss=1"
Chen, C.Saclier, M.Chantrel, J.Mella, S.Chiche, A.Li, H.2023-12-13doi:10.1101/2023.12.12.571148Cold Spring Harbor Laboratory Press2023-12-13
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Extensive variation and strain-specificity in dengue virus susceptibility among African Aedes aegypti populations
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https://biorxiv.org/cgi/content/short/2023.12.14.571617v1?rss=1"
Dabo, S.Henrion-Lacritick, A.Lecuyer, A.Jiolle, D.Paupy, C.Ayala, D.da Veiga Leal, S.Badolo, A.Vega-Rua, A.Sylla, M.Akorli, J.Otoo, S.Lutomiah, J.Sang, R.Mutebi, J.-P.Saleh, M.-C.Rose, N.McBride, C.Lambrechts, L.2023-12-14doi:10.1101/2023.12.14.571617Cold Spring Harbor Laboratory Press2023-12-14
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Chromatin remodeling initiates transcriptional and post-transcriptional silencing in Neurospora
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https://biorxiv.org/cgi/content/short/2024.01.15.575522v1?rss=1"
Carlier, F.Castro Ramirez, S.Kilani, J.Chehboub, S.Gladyshev, E.2024-01-15doi:10.1101/2024.01.15.575522Cold Spring Harbor Laboratory Press2024-01-15
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Macrophage-induced reduction of bacteriophage density limits the efficacy of in vivo pulmonary phage therapy
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https://biorxiv.org/cgi/content/short/2024.01.16.575879v1?rss=1"
Zborowsky, S.Seurat, J.Balacheff, Q.Minh, C. N. N.Titecat, M.Evrard, E.Rodriguez-Gonzalez, R. A.Marchi, J.Weitz, J. W.Debarbieux, L.2024-01-16doi:10.1101/2024.01.16.575879Cold Spring Harbor Laboratory Press2024-01-16
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Identification of novel origins of transfer across bacterial plasmids
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https://biorxiv.org/cgi/content/short/2024.01.30.577996v1?rss=1"
Ares-Arroyo, M.Nucci, A.Rocha, E. P. C.2024-01-30doi:10.1101/2024.01.30.577996Cold Spring Harbor Laboratory Press2024-01-30
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Triplex real-time PCR ZKIR-T assay for simultaneous detection of the Klebsiella pneumoniae species complex and identification of K. pneumoniae sensu stricto
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https://biorxiv.org/cgi/content/short/2024.02.02.578617v1?rss=1"
Ligowska-Marzeta, M.Barbier, E.Rodrigues, C.Piveteau, P.Schroeder Hansen, D.Hartmann, A.Moller-Nielsen, E.Brisse, S.2024-02-03doi:10.1101/2024.02.02.578617Cold Spring Harbor Laboratory Press2024-02-03
<![CDATA[
Atypical landscape of transposable elements in the large genome of Aedes aegypti
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https://biorxiv.org/cgi/content/short/2024.02.07.579293v1?rss=1"
Daron, J.Bergman, A.Lopez-Maestre, H.LAMBRECHTS, L.2024-02-08doi:10.1101/2024.02.07.579293Cold Spring Harbor Laboratory Press2024-02-08
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Structures of the Foamy virus fusion protein reveal an unexpected link with the F protein of paramyxo- and pneumoviruses
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https://biorxiv.org/cgi/content/short/2024.02.09.579661v1?rss=1"
Fernandez, I.Bontems, F.Brun, D.Coquin, Y.Goverde, C. A.Correia, B. E.Gessain, A.Buseyne, F.Rey, F. A.Backovic, M.2024-02-09doi:10.1101/2024.02.09.579661Cold Spring Harbor Laboratory Press2024-02-09
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Structural basis of TMPRSS2 zymogen activation and recognition by the HKU1 seasonal coronavirus
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https://biorxiv.org/cgi/content/short/2024.02.21.581378v1?rss=1"
Fernandez, I.Saunders, N.Duquerroy, S.Bolland, W. H.Arbabian, A.Baquero, E.Blanc, C.Lafaye, P.Haouz, A.Buchrieser, J.Schwartz, O.Rey, F. A.2024-02-22doi:10.1101/2024.02.21.581378Cold Spring Harbor Laboratory Press2024-02-22
<![CDATA[
Symmetry breaking and fate divergence during lateral inhibition in Drosophila
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https://biorxiv.org/cgi/content/short/2024.03.11.583933v1?rss=1"
phan, m.-s.Kim, J.-m.picciotto, c.couturier, l.veits, n.Mazouni, K.schweisguth, f.2024-03-13doi:10.1101/2024.03.11.583933Cold Spring Harbor Laboratory Press2024-03-13
<![CDATA[
Bacterial strain nomenclature in the genomic era: Life Identification Numbers using a gene-by-gene approach
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https://biorxiv.org/cgi/content/short/2024.03.11.584534v1?rss=1"
Palma, F.Hennart, M.Jolley, K. A.Crestani, C.Wyres, K. L.Bridel, S.Yeats, C. A.Brancotte, B.Raffestin, B.David, S.Lam, M. M. C.Izdebski, R.Passet, V.Rodrigues, C.Rethoret-Pasty, M.Maiden, M. C. J.Aanensen, D. M.Holt, K. E.Criscuolo, A.Brisse, S.2024-03-12doi:10.1101/2024.03.11.584534Cold Spring Harbor Laboratory Press2024-03-12
<![CDATA[
Convergent gene expression in epithelial cells illuminates the evolution of uterine receptivity
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https://biorxiv.org/cgi/content/short/2024.03.13.584751v1?rss=1"
Brulport, A.Gazda, M. A.Daunesse, M.Liorzou, E.Raquillet, B.Lepelletier, A.Sopena-Rios, M.Regnard, P.Fellmann, L.Faccin, L.Garbit, S.Cermolacce, A.Kondova, I.Raliou, M.Marcellin, L.Abo, C.Doridot, L.Berthelot, C.2024-03-14doi:10.1101/2024.03.13.584751Cold Spring Harbor Laboratory Press2024-03-14
<![CDATA[
LarvaTagger: Manual and automatic tagging of Drosophila larval behaviour
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https://biorxiv.org/cgi/content/short/2024.03.18.585197v1?rss=1"
Laurent, F.Blanc, A.May, L.Gandara, L.Cocanougher, B. T.Jones, B. M. W.Hague, P.Barre, C.Vestergaard, C. L.Crocker, J.Zlatic, M.Jovanic, T.Masson, J.-B.2024-03-19doi:10.1101/2024.03.18.585197Cold Spring Harbor Laboratory Press2024-03-19
<![CDATA[
Consensus Clustering for Robust Bioinformatics Analysis
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https://biorxiv.org/cgi/content/short/2024.03.21.586064v1?rss=1"
Yousefi, B.Schwikowski, B.2024-03-23doi:10.1101/2024.03.21.586064Cold Spring Harbor Laboratory Press2024-03-23
<![CDATA[
MAPPING CHANGES OF MIRNA-MRNA NETWORKS IN LEISHMANIA-INFECTED MACROPHAGES PREDICTS REGULATORY MIRNA-TF LOOPS AS NOVEL TARGETS OF PARASITE IMMUNE SUBVERSION
]]>
https://biorxiv.org/cgi/content/short/2024.03.24.586456v1?rss=1"
Gharsallah, C.Lecoeur, H.Varet, H.Legendre, R.Sismeiro, O.Coppee, J.-Y.Proux, C.Prina, E.Spaeth, G. F.2024-03-24doi:10.1101/2024.03.24.586456Cold Spring Harbor Laboratory Press2024-03-24
<![CDATA[
Notch3 is a genetic modifier of NODAL signalling for patterning asymmetry during mouse heart looping
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https://biorxiv.org/cgi/content/short/2024.03.25.586543v1?rss=1"
Holm Bonnelykke, T.Chabry, M.-A.Perthame, E.Desgrange, A.Meilhac, S.2024-03-28doi:10.1101/2024.03.25.586543Cold Spring Harbor Laboratory Press2024-03-28
<![CDATA[
Mixed clonal-aggregative multicellularity entrained by extreme salinity fluctuations in a close relative of animals
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https://biorxiv.org/cgi/content/short/2024.03.25.586565v1?rss=1"
Ros-Rocher, N.Reyes-Rivera, J.Foroughijabbari, Y.Combredet, C.Larson, B. T.Coyle, M. C.Houtepen, E. A. T.Vermeij, M. J. A.King, N.Brunet, T.2024-03-27doi:10.1101/2024.03.25.586565Cold Spring Harbor Laboratory Press2024-03-27
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Coordinated regulation of osmotic imbalance by c-di-AMP shapes beta-lactam tolerance in Group B Streptococcus
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https://biorxiv.org/cgi/content/short/2024.03.27.586946v1?rss=1"
Brissac, T.Guyonnet, C.Sadouni, A.Hernandez Montoya, A.Jacquemet, E.Legendre, R.Sismeiro, O.Trieu-Cuot, P.Lanotte, P.Tazi, A.Firon, A.2024-03-27doi:10.1101/2024.03.27.586946Cold Spring Harbor Laboratory Press2024-03-27
<![CDATA[
Type 1 diabetes and parasite infection: an exploratory study in the NOD mouse
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https://biorxiv.org/cgi/content/short/2024.03.27.586975v1?rss=1"
Giraud, E.Fiette, L.Melanitou, E.2024-03-27doi:10.1101/2024.03.27.586975Cold Spring Harbor Laboratory Press2024-03-27
<![CDATA[
Evolutionary insights into the emergence of virulent Leptospira spirochetes
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https://biorxiv.org/cgi/content/short/2024.04.02.587687v1?rss=1"
Giraud-Gatineau, A.Nieves, C.Harrison, L.Benaroudj, N.Veyrier, F. J.Picardeau, M.2024-04-02doi:10.1101/2024.04.02.587687Cold Spring Harbor Laboratory Press2024-04-02
<![CDATA[
Colonization of Anopheles coustani, a neglected malaria vector in Madagascar
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https://biorxiv.org/cgi/content/short/2024.04.16.589755v1?rss=1"
Andrianinarivomanana, T. M.Randrianaivo, F. T.Andriamiarimanana, M. R.Razafimamonjy, M. R.Velonirina, H. J. S.Puchot, N.Girod, R.Bourgouin, C.2024-04-20doi:10.1101/2024.04.16.589755Cold Spring Harbor Laboratory Press2024-04-20
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Atypical Audio-Visual Neural Synchrony and Speech Processing in children with Autism Spectrum Disorder
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https://biorxiv.org/cgi/content/short/2024.04.19.590044v1?rss=1"
Wang, X.Bouton, S.Kojovic, N.Giraud, A.-L.Schaer, M.2024-04-19doi:10.1101/2024.04.19.590044Cold Spring Harbor Laboratory Press2024-04-19
<![CDATA[
Differential alpha-Synuclein-induced Autophagy Dysfunction in Neuronal and Microglial Cells drives Tunneling Nanotubes and Aggregate Spread to Microglia
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https://biorxiv.org/cgi/content/short/2024.04.19.590207v1?rss=1"
Chakraborty, R.Samella, P.Nonaka, T.Hasegawa, M.Zurzolo, C.2024-04-20doi:10.1101/2024.04.19.590207Cold Spring Harbor Laboratory Press2024-04-20
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Communication between DNA polymerases and Replication Protein A within the archaeal replisome
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https://biorxiv.org/cgi/content/short/2024.04.29.591592v1?rss=1"
Martinez-Carranza, M.Vialle, L.Madru, C.Cordier, F.Dizkirici Tekpinar, A.Haouz, A.Legrand, P.Le Meur, R. A.England, P.Dulermo, R.Guijarro, I. J.Henneke, G.Sauguet, L.2024-04-29doi:10.1101/2024.04.29.591592Cold Spring Harbor Laboratory Press2024-04-29
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Late killing of Plasmodium berghei in the liver by an anti-circumsporozoite protein monoclonal antibody
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https://biorxiv.org/cgi/content/short/2024.04.30.591864v1?rss=1"
Aguirre-Botero, M. C.Pacios, O.Celli, S.Aliprandini, E.Gladston, A.Thiberge, J.-M.Formaglio, P.Amino, R.2024-04-30doi:10.1101/2024.04.30.591864Cold Spring Harbor Laboratory Press2024-04-30
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Spatial dynamics of peripheral and central nervous system infection by an interferon-inducing neuroinvasive virus
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https://biorxiv.org/cgi/content/short/2024.05.19.594871v1?rss=1"
Laghi, V.Boucontet, L.Wiggett, H.Banerjee, P.Simion, M.Maggi, L.Ciura, S.Guedj, J.Colucci-Guyon, E.Levraud, J.-P.2024-05-19doi:10.1101/2024.05.19.594871Cold Spring Harbor Laboratory Press2024-05-19
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A recombinant CHIKV-NLuc virus identifies chondrocytes as target of Chikungunya virus in a immunocompetent mouse model
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https://biorxiv.org/cgi/content/short/2024.05.20.594924v1?rss=1"
Legros, V.Belarbi, E.Jeannin, p.Kuemmerer, B.Hardy, D.Despres, P.Gessain, A.Roques, P.Ceccaldi, P.-E.Choumet, V.2024-05-20doi:10.1101/2024.05.20.594924Cold Spring Harbor Laboratory Press2024-05-20
<![CDATA[
Chlamydia-driven ISG15 expression dampens the immune response of epithelial cells independently of ISGylation
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https://biorxiv.org/cgi/content/short/2024.05.27.596023v1?rss=1"
Wu, Y.Liu, C.Tang, C.Niragire, B.Levy-Zauberman, Y.Adapen, C.Vernay, T.Hugueny, J.Baud, V.Subtil, A.2024-05-27doi:10.1101/2024.05.27.596023Cold Spring Harbor Laboratory Press2024-05-27
<![CDATA[
Molecular and epistatic interactions between pioneer transcription factors shape nucleosome dynamics and cell differentiation
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https://biorxiv.org/cgi/content/short/2024.05.27.596047v1?rss=1"
Coux, R. X.Dubois, A.Chervova, A.Festuccia, N.Gonzalez, I.Vandormael-Pournin, S.Cohen-Tannoudji, M.Navarro, P.2024-05-27doi:10.1101/2024.05.27.596047Cold Spring Harbor Laboratory Press2024-05-27
<![CDATA[
Imperfect hairpins formed by CTG trinucleotide repeats are heteroduplex DNA molecules in living cells
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https://biorxiv.org/cgi/content/short/2024.06.04.597286v1?rss=1"
Viterbo, D.Dupaigne, P.Kaminski, P. A.Dejardin, F.Petres, S.Le Cam, E.Richard, G.-F.2024-06-04doi:10.1101/2024.06.04.597286Cold Spring Harbor Laboratory Press2024-06-04
<![CDATA[
Metabolic imprint of an intracellular pathogen drives histone hypermethylation and tunes the host transcriptional response to infection
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https://biorxiv.org/cgi/content/short/2024.06.04.597420v1?rss=1"
Charendoff, C. I.Louchez, F. V.Wu, Y.Dolat, L.Velasco, G.Perrinet, S.Torres, A. G.Blanchet, L.Duchateau, M.Gianetto, Q. G.Matondo, M.Del Maestro, L.Ait-Si-Ali, S.Bonhomme, F.Millot, G.Ribas de Pouplana, L.Martinez, E. D.Valdivia, R.Subtil, A.2024-06-05doi:10.1101/2024.06.04.597420Cold Spring Harbor Laboratory Press2024-06-05
<![CDATA[
Contribution of the Type 3 Secretion System to immunogenicity of a live Yersinia pseudotuberculosis plague vaccine
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https://biorxiv.org/cgi/content/short/2024.06.11.598433v1?rss=1"
Derbise, A.Guillas, C.Echenique-Rivera, H.Carniel, E.Gerke, C.Pizarro-Cerda, J.Demeure, C. E.2024-06-11doi:10.1101/2024.06.11.598433Cold Spring Harbor Laboratory Press2024-06-11
<![CDATA[
No innocent bystanders: pertussis vaccination epitomizes evolutionary parallelisms between Bordetella parapertussis and B. pertussis
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https://biorxiv.org/cgi/content/short/2024.06.18.599646v1?rss=1"
Bouchez, V.Moreno-Mingorance, A.Mir-Cros, A.Landier, A.Armatys, N.Guillot, S.Teresa Martin-Gomez, M.Rodrigues, C.Toubiana, J.Bento, A. I.Weigand, M. R.Gonzalez-Lopez, J. J.Brisse, S.2024-06-21doi:10.1101/2024.06.18.599646Cold Spring Harbor Laboratory Press2024-06-21
<![CDATA[
Biogenesis of DNA-carrying extracellular vesicles by the dominant human gut methanogenic archaeon
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https://biorxiv.org/cgi/content/short/2024.06.22.600173v1?rss=1"
Baquero, D. P.Borrel, G.Gazi, A.Martin-Gallausiaux, C.Cvirkaite-Krupovic, V.Commere, P.-H.Pende, N.Tachon, S.Sartori-Rupp, A.Douche, T.Matondo, M.Gribaldo, S.Krupovic, M.2024-06-22doi:10.1101/2024.06.22.600173Cold Spring Harbor Laboratory Press2024-06-22
<![CDATA[
A family of lanthipeptides with anti-phage function
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https://biorxiv.org/cgi/content/short/2024.06.26.600839v1?rss=1"
Shomar, H.Tesson, F.Guillaume, M.Ongenae, V.Le Bot, M.Georjon, H.Mordret, E.Zhang, L.van Wezel, G. P.Rozen, D.Briegel, A.Zirah, S.Claessen, D.Li, Y.Bernheim, A.2024-06-27doi:10.1101/2024.06.26.600839Cold Spring Harbor Laboratory Press2024-06-27
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Beta-1,6-glucan plays a central role in the structure and remodeling of the bilaminate fungal cell wall
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https://biorxiv.org/cgi/content/short/2024.06.30.601427v1?rss=1"
Bekirian, C.Valsecchi, I.Bachellier-Bassi, S.Scandola, C.Guijarro, J. I.Chauvel, M.Mourer, T.Gow, N.Aimanianda Bopaiah, V. K.d'Enfert, C.Fontaine, T.2024-07-01doi:10.1101/2024.06.30.601427Cold Spring Harbor Laboratory Press2024-07-01
<![CDATA[
A Vago-like gene enhances dengue and Zika virus dissemination in Aedes aegypti
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https://biorxiv.org/cgi/content/short/2024.07.01.601473v1?rss=1"
Couderc, E.Crist, A. B.Daron, J.Varet, H.Van Hout, F. A. H.Miesen, P.Palatini, U.Dabo, S.Vial, T.LAMBRECHTS, L.Merkling, S.2024-07-03doi:10.1101/2024.07.01.601473Cold Spring Harbor Laboratory Press2024-07-03
<![CDATA[
Sedentary chromosomal integrons as biobanks of bacterial anti-phage defence systems
]]>
https://biorxiv.org/cgi/content/short/2024.07.02.601686v1?rss=1"
Darracq, B.Littner, E.Brunie, M.Bos, J.Kaminski, P. A.Depardieu, F.Slesak, W.Debatisse, K.Touchon, M.Bernheim, A.Bikard, D.Le Roux, F.Mazel, D.Rocha, E. P.Loot, C.2024-07-03doi:10.1101/2024.07.02.601686Cold Spring Harbor Laboratory Press2024-07-03
<![CDATA[
Fine-tuning of a CRISPRi screen in the seventh pandemic Vibrio cholerae
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https://biorxiv.org/cgi/content/short/2024.07.03.601881v1?rss=1"
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org.highwire.dtl.DTLVardef@bab54aorg.highwire.dtl.DTLVardef@1d412c6org.highwire.dtl.DTLVardef@1cba6borg.highwire.dtl.DTLVardef@12d11d_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>Debatisse, K.Niault, T.Peeters, S.Maire, A.Darracq, B.Baharoglu, Z.Bikard, D.Mazel, D.Loot, C.2024-07-03doi:10.1101/2024.07.03.601881Cold Spring Harbor Laboratory Press2024-07-03
<![CDATA[
A DIY guide for image-based spatial transcriptomic: TLS as a case example
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https://biorxiv.org/cgi/content/short/2024.07.03.601914v1?rss=1"
Defard, t.DESRENTES, A.Fouillade, C.Mueller, F.2024-07-05doi:10.1101/2024.07.03.601914Cold Spring Harbor Laboratory Press2024-07-05
<![CDATA[
A fast and robust gene knockout method for Salpingoeca rosetta clarifies the genetics of choanoflagellate multicellular development
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https://biorxiv.org/cgi/content/short/2024.07.13.603360v1?rss=1"
Combredet, C.Brunet, T.2024-07-13doi:10.1101/2024.07.13.603360Cold Spring Harbor Laboratory Press2024-07-13
<![CDATA[
SARS-CoV-2 entry and fusion are independent of ACE2 localization to lipid rafts
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https://biorxiv.org/cgi/content/short/2024.07.13.603361v1?rss=1"
Bolland, W.Buchrieser, J.Schwartz, O.Casartelli, N.Porrot, F.Guivel-Benhassine, F.Marechal, I.Petiot, C.2024-07-16doi:10.1101/2024.07.13.603361Cold Spring Harbor Laboratory Press2024-07-16
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Identification of V. parvula and S. gordonii adhesins mediating co-aggregation and its impact on physiology and mixed biofilm structure
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https://biorxiv.org/cgi/content/short/2024.07.16.603716v1?rss=1"
DORISON, L.BECHON, N.MARTIN-GALLAUSIAUX, C.CHAMORRO RODRIGUEZ, S. V.VITRENKO, Y.OUAZAHROU, R.VILLA, R.DESCHAMPS, J.BRIANDET, R.GRIBALDO, S.GHIGO, J.-M.BELOIN, C.2024-07-16doi:10.1101/2024.07.16.603716Cold Spring Harbor Laboratory Press2024-07-16
<![CDATA[
The spread of antibiotic resistance is driven by plasmids amongst the fastest evolving and of broadest host range
]]>
https://biorxiv.org/cgi/content/short/2024.07.23.604842v1?rss=1"
Coluzzi, C.Rocha, E. P. C.2024-07-24doi:10.1101/2024.07.23.604842Cold Spring Harbor Laboratory Press2024-07-24
<![CDATA[
Mechanisms Ensuring Fidelity of Family X DNA Polymerases in Programmed DNA rearrangements in Paramecium tetraurelia
]]>
https://biorxiv.org/cgi/content/short/2024.07.26.605286v1?rss=1"
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]]>Nourisson, A.Missoury, S.Haouz, A.Delarue, M.2024-07-26doi:10.1101/2024.07.26.605286Cold Spring Harbor Laboratory Press2024-07-26
<![CDATA[
Logan: Planetary-Scale Genome Assembly Surveys Life's Diversity
]]>
https://biorxiv.org/cgi/content/short/2024.07.30.605881v1?rss=1"
200 million plastic-degrading enzyme homologs, and validate novel enzymes with catalytic activities exceeding current reference standards. Further, we vastly expand the known diversity of proteins (30-fold over UniRef50), plasmids (22-fold over PLSDB), P4 satellites (4.5-fold), and the recently described Obelisk RNA elements (3.7-fold). Logan also enables ecological and biomedical data mining, such as global tracking of antimicrobial resistance genes and the characterization of viral reactivation across millions of human BioSamples. By transforming the SRA, Logan democratizes access to the worlds public genetic data and opens frontiers in biotechnology, molecular ecology, and global health.
]]>Chikhi, R.Raffestin, B.Korobeynikov, A.Edgar, R. C.Babaian, A.2024-07-31doi:10.1101/2024.07.30.605881Cold Spring Harbor Laboratory Press2024-07-31
<![CDATA[
Incomplete lytic cycle of a widespread Bacteroides bacteriophage leads to the formation of defective viral particles
]]>
https://biorxiv.org/cgi/content/short/2024.08.07.606950v1?rss=1"
Vendrell-Fernandez, S.Beamud, B.Abou-Haydar, Y.Am de Sousa, J.Burlaud-Gaillard, J.Kornobis, E.Raynal, B.Vinh, J.Bikard, D.Ghigo, J.-M.2024-08-07doi:10.1101/2024.08.07.606950Cold Spring Harbor Laboratory Press2024-08-07
<![CDATA[
Universal dynamics of cohesin-mediated loop extrusion
]]>
https://biorxiv.org/cgi/content/short/2024.08.09.605990v1?rss=1"
Sabate, T.Lelandais, B.Robert, M.-C.Szalay, M.Tinevez, J.-Y.Bertrand, E.Zimmer, C.2024-08-10doi:10.1101/2024.08.09.605990Cold Spring Harbor Laboratory Press2024-08-10
<![CDATA[
Escape of SARS-CoV-2 variants KP1.1, LB.1 and KP3.3 from approved monoclonal antibodies
]]>
https://biorxiv.org/cgi/content/short/2024.08.20.608835v1?rss=1"
Planas, D.Staropoli, I.Planchais, C.Yab, E.Jeyarajah, B.Rahou, Y.Guivel-Benhassine, F.Prot, M.Lemoine, F.Enouf, V.Simon-Loriere, E.Mouquet, H.Rameix-Welti, M.-A.Schwartz, O.2024-08-21doi:10.1101/2024.08.20.608835Cold Spring Harbor Laboratory Press2024-08-21
<![CDATA[
Exploring the diversity of anti-defense systems across prokaryotes, phages, and mobile genetic elements
]]>
https://biorxiv.org/cgi/content/short/2024.08.21.608784v1?rss=1"
Tesson, F.Huiting, E.Wei, L.Ren, J.Johnson, M. C.Planel, R.Cury, J.Feng, Y.Bondy-Denomy, J.Bernheim, A.2024-08-21doi:10.1101/2024.08.21.608784Cold Spring Harbor Laboratory Press2024-08-21
<![CDATA[
Genomic Epidemiology and Microevolution of the Zoonotic Pathogen Corynebacterium ulcerans
]]>
https://biorxiv.org/cgi/content/short/2024.08.22.609154v1?rss=1"
Crestani, C.Passet, V.Rethoret-Pasty, M.Criscuolo, A.Zidane, N.Bremont, S.Badell, E.Brisse, S.2024-08-22doi:10.1101/2024.08.22.609154Cold Spring Harbor Laboratory Press2024-08-22
<![CDATA[
Micro-C reveals MORC/ApiAP2-mediated links between distant, functionally related genes in the human malaria parasite
]]>
https://biorxiv.org/cgi/content/short/2024.08.28.610079v1?rss=1"
Singh, P.Serizay, J.Couble, J.Cabahug, M. D.Rosa, C.Chen, P.Scherf, A.Koszul, R.Baumgarten, S.Bryant, J. M.2024-08-28doi:10.1101/2024.08.28.610079Cold Spring Harbor Laboratory Press2024-08-28
<![CDATA[
IL-23 tunes inflammatory functions of human mucosal-associated invariant T (MAIT) cells
]]>
https://biorxiv.org/cgi/content/short/2024.08.29.609178v1?rss=1"
Camard, L.Stephen, T.Yahia-Cherbal, H.Guillemot, V.Mella, S.Baillet, V.Lopez-Maestre, H.Capocefalo, D.Cantini, L.Leloup, C.Marsande, J.Sienes Bailo, J.Dangien, A.Pietrosemoli, N.Hasan, M.Wang, H.Eckle, S. B. G.Fourie, A. M.Greving, C.Shaikh, B. J.Parker, R.Cua, D. J.Bianchi, E.Rogge, L.2024-08-30doi:10.1101/2024.08.29.609178Cold Spring Harbor Laboratory Press2024-08-30
<![CDATA[
In vivo detection of protein-protein interactions with single molecule resolution
]]>
https://biorxiv.org/cgi/content/short/2024.09.06.611644v1?rss=1"
Davi, M.Ladant, D.2024-09-06doi:10.1101/2024.09.06.611644Cold Spring Harbor Laboratory Press2024-09-06
<![CDATA[
TYPE THREE SECRETION SYSTEM-INDUCED MECHANOPORATION OF VACUOLAR MEMBRANES
]]>
https://biorxiv.org/cgi/content/short/2024.09.19.613840v1?rss=1"
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org.highwire.dtl.DTLVardef@1669028org.highwire.dtl.DTLVardef@8259cborg.highwire.dtl.DTLVardef@1d522caorg.highwire.dtl.DTLVardef@1df0f2d_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>SWISTAK, L.Albert, M.Valenzuela, C.Gokerkucuk, E. B.Bontems, F.Gazi, A. D.Tachon, S.Sartori-Rupp, A.Lesser, C. F.Paul-Gilloteaux, P.Tinevez, J.-Y.Vos, M.Enninga, J.2024-09-19doi:10.1101/2024.09.19.613840Cold Spring Harbor Laboratory Press2024-09-19
<![CDATA[
Properties of DNA in concentrated aqueous solutions of LiCl suggest transition to C-DNA
]]>
https://biorxiv.org/cgi/content/short/2024.09.20.613475v1?rss=1"
Mazur, A.Maaloum, M.Gladyshev, E.2024-09-23doi:10.1101/2024.09.20.613475Cold Spring Harbor Laboratory Press2024-09-23
<![CDATA[
Introducing Haptic Feedback in Real-Time fMRI Neurofeedback: A Novel Approach to Modulate Primary Motor Cortex Activity
]]>
https://biorxiv.org/cgi/content/short/2024.09.30.614977v1?rss=1"
Fleury, M.Cloerec, P.Duche, Q.Lioi, G.Lecuyer, A.2024-10-01doi:10.1101/2024.09.30.614977Cold Spring Harbor Laboratory Press2024-10-01
<![CDATA[
Myocarditis and neutrophil-mediated vascular leakage but not cytokine storm associated with fatal murine leptospirosis
]]>
https://biorxiv.org/cgi/content/short/2024.10.01.616081v1?rss=1"
Papadopoulos, S.Hardy, D.Vernel-Pauillac, F.Tichit, M.Gomberts Boneca, I.Werts, C.2024-10-03doi:10.1101/2024.10.01.616081Cold Spring Harbor Laboratory Press2024-10-03
<![CDATA[
Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with the nuclear speckle
]]>
https://biorxiv.org/cgi/content/short/2024.10.06.616889v1?rss=1"
Tomasini, C. D.Cuche, C.Ay, S.Collard, M.Cui, B.Rashid, M.Bhattacharjee, S.Buchrieser, J.Luchsinger, C.Bertelli, C.Uversky, V.Diaz-Griffero, F.Di Nunzio, F.2024-10-07doi:10.1101/2024.10.06.616889Cold Spring Harbor Laboratory Press2024-10-07
<![CDATA[
Intranasal delivery of a broadly neutralizing single domain antibody targeting ACE2 protects against SARS-CoV-2 infection
]]>
https://biorxiv.org/cgi/content/short/2024.10.11.617877v1?rss=1"
Blachier, S.Fernandez, I.Conquet, L.Giraud, E.Staropoli, I.Michel, V.Szilagyi, F.Guez, S.Boucharlat, A.Chiaravalli, J.Tran-Rajau, J.Dufour, E.Petres, S.Planas, D.Montagutelli, X.Agou, F.Rey, F. A.Lafaye, P.Enninga, J.Ayme, G.Schwartz, O.Brelot, A.2024-10-11doi:10.1101/2024.10.11.617877Cold Spring Harbor Laboratory Press2024-10-11
<![CDATA[
Single-cell and in situ spatial analyses reveal the diversity of newly born hematopoietic stem cells and of their niches
]]>
https://biorxiv.org/cgi/content/short/2024.10.14.618250v1?rss=1"
Torcq, L.Vivier, C.Schmutz, S.Loe-Mie, Y.Schmidt, A.2024-10-15doi:10.1101/2024.10.14.618250Cold Spring Harbor Laboratory Press2024-10-15
<![CDATA[
Virulence regulates and boosts CRISPR-Cas9 immunity in Group B Streptococcus
]]>
https://biorxiv.org/cgi/content/short/2024.10.24.620037v1?rss=1"
Pastuszka, A.Mazzuoli, M.-V.Crestani, C.Deborde, L.Sismeiro, O.Lemaire, C.Rong, V.Gominet, M.Jacquemet, E.Legendre, R.Lanotte, P.Firon, A.2024-10-24doi:10.1101/2024.10.24.620037Cold Spring Harbor Laboratory Press2024-10-24
<![CDATA[
Culture of pluripotent stem cells in microscale droplets modulates differentiation and tissue patterning towards organoids on chip
]]>
https://biorxiv.org/cgi/content/short/2024.10.25.620219v1?rss=1"
Vertti-Quintero, N.Delahousse, C.Aristov, A.Traboulsi, T.Cossec, J.-C.Baroud, C.Sart, S.2024-10-25doi:10.1101/2024.10.25.620219Cold Spring Harbor Laboratory Press2024-10-25
<![CDATA[
Backtracking Metabolic Dynamics in Single Cells Predicts Bacterial Replication in Human Macrophages
]]>
https://biorxiv.org/cgi/content/short/2024.10.28.620606v1?rss=1"
Drame, M.Ershov, D.Martyn, J. E.Tinevez, J.-Y.Buchrieser, C.Escoll, P.2024-10-28doi:10.1101/2024.10.28.620606Cold Spring Harbor Laboratory Press2024-10-28
<![CDATA[
autoFISH - a modular toolbox for sequential smFISH experiments
]]>
https://biorxiv.org/cgi/content/short/2024.11.14.623566v1?rss=1"
Weber, C.Defard, T.Lelek, M.Laporte, H.Mallick, A.Londono-Vallejo, J.-A.Walter, T.Fouillade, C.Gariboldi, M. I.Muller, F.2024-11-15doi:10.1101/2024.11.14.623566Cold Spring Harbor Laboratory Press2024-11-15
<![CDATA[
Transcriptional landscape of the archaeal cell cycle is broadly conserved in eukaryotes
]]>
https://biorxiv.org/cgi/content/short/2024.11.20.624502v1?rss=1"
Gomez-Raya-Vilanova, M. V.Teuliere, J.Medvedeva, S.Dai, Y.Corel, E.Lopez, P.Lapointe, F.-J.Bhattacharya, D.Haraoui, L.-P.Turc, E.Monot, M.Cvirkaite-Krupovic, V.Bapteste, E.Krupovic, M.2024-11-20doi:10.1101/2024.11.20.624502Cold Spring Harbor Laboratory Press2024-11-20
<![CDATA[
Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti
]]>
https://biorxiv.org/cgi/content/short/2024.11.26.625377v1?rss=1"
Bergman, A.Crist, A. B.Lopez-Maestre, H.Blanc, H.Castello-Sanjuan, M.Frangeul, L.Varet, H.Daron, J.Merkling, S. H.Saleh, M. C.Lambrechts, L.2024-11-28doi:10.1101/2024.11.26.625377Cold Spring Harbor Laboratory Press2024-11-28
<![CDATA[
Global evolutionary patterns of Yersinia pestis and its spread into Africa
]]>
https://biorxiv.org/cgi/content/short/2024.11.26.625443v1?rss=1"
Mas Fiol, G.Lemoine, F.Mornico, D.Bouvier, G.Andrades Valtuena, A.Duchene, S.Campagne, P.Baliere, C.Kwasiborski, A.Caro, V.Beau, R.Savin, C.Cespedes, M.Rajerison, M.Shako, J.-C.Carniel, E.Slavin, P.Rascovan, N.Pizarro-Cerda, J.2024-11-28doi:10.1101/2024.11.26.625443Cold Spring Harbor Laboratory Press2024-11-28
<![CDATA[
Influenza A virus-induced production of PI4P at the endoplasmic reticulum involves ATG16L1 and promotes the egress of viral ribonucleoproteins
]]>
https://biorxiv.org/cgi/content/short/2024.11.29.625996v1?rss=1"
Alemany, C.Da Graca, J.Giai Gianetto, Q.Paisant, S.Dupont, M.Douche, T.Isel, C.Delevoye, C.Danglot, L.Matondo, M.Morel, E.Brault, J.-B.Naffakh, N.2024-11-30doi:10.1101/2024.11.29.625996Cold Spring Harbor Laboratory Press2024-11-30
<![CDATA[
The SARS-CoV-2 envelope PDZ Binding Motif acts as a virulence factor disrupting host's epithelial cell-cell junctions
]]>
https://biorxiv.org/cgi/content/short/2024.12.10.627528v1?rss=1"
Alvarez, F.Melo, G. D. d.Larrous, F.Kergoat, L.Boeda, B.Michel, V.Seilhean, D.Tichit, M.Hing, D.Hardy, D.Kornobis, E.Bourhy, H.Wolff, N.Caillet-Saguy, C.2024-12-10doi:10.1101/2024.12.10.627528Cold Spring Harbor Laboratory Press2024-12-10
<![CDATA[
Intraflagellar Transport Selectivity Occurs with the Proximal Portion of the Trypanosome Flagellum
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https://biorxiv.org/cgi/content/short/2024.12.13.628094v1?rss=1"
Alves, A. A.Jung, J.Monneron, G.Vaucelle, H.Fort, C.Buisson, J.Schietroma, C.BASTIN, P.2024-12-17doi:10.1101/2024.12.13.628094Cold Spring Harbor Laboratory Press2024-12-17
<![CDATA[
Hamsters with long Covid exhibits a neurodegenerative signature in the brainstem
]]>
https://biorxiv.org/cgi/content/short/2024.12.16.628627v1?rss=1"
Coleon, A.Larrous, F.Kergoat, L.Tichit, M.Hardy, D.Obadia, T.Kornobis, E.Bourhy, H.de Melo, G. D.2024-12-16doi:10.1101/2024.12.16.628627Cold Spring Harbor Laboratory Press2024-12-16
<![CDATA[
Characterizing particle dynamics in live imaging through stochastic physical models and machine learning
]]>
https://biorxiv.org/cgi/content/short/2024.12.17.628916v1?rss=1"
Nardi, G.Santos Sano, M.Bilay, M.Brelot, A.Olivo-Marin, J.-C.Lagache, T.2024-12-20doi:10.1101/2024.12.17.628916Cold Spring Harbor Laboratory Press2024-12-20
<![CDATA[
Antiviral activity of Tecovirimat against Mpox virus clades 1a, 1b, 2a and 2b
]]>
https://biorxiv.org/cgi/content/short/2024.12.20.629622v1?rss=1"
Postal, J.Guivel-Benhassine, F.Porrot, F.Grassin, Q.Crook, J.Vernuccio, R.Caro, V.Vanhomwegen, J.Guardado-Calvo, P.Simon-Loriere, E.Dacheux, L.Manuguerra, J.-C.Schwartz, O.2024-12-23doi:10.1101/2024.12.20.629622Cold Spring Harbor Laboratory Press2024-12-23
<![CDATA[
Induction of Senescence During Postpartum Mammary Gland Involution supports tissue remodeling and promotes postpartum tumorigenesis
]]>
https://biorxiv.org/cgi/content/short/2024.12.29.630686v1?rss=1"
li, H.Chiche, A.Charifou, E.Djoual, L.WANG, S.Temime, L.Saclier, M.WANG, S.Chantrel, J.2024-12-29doi:10.1101/2024.12.29.630686Cold Spring Harbor Laboratory Press2024-12-29
<![CDATA[
DNA supercoiling modulates eukaryotic transcription in a gene-orientation dependent manner
]]>
https://biorxiv.org/cgi/content/short/2025.01.03.631213v1?rss=1"
Morao, A. K.Chervova, A.Zhao, Y.Ercan, S.Cecere, G.2025-01-03doi:10.1101/2025.01.03.631213Cold Spring Harbor Laboratory Press2025-01-03
<![CDATA[
Distinct origin and fate for fetal hematopoietic progenitors
]]>
https://biorxiv.org/cgi/content/short/2025.01.08.631951v1?rss=1"
Soares-da-Silva, F.Nogueira, G.Mailhe, M.-P.Freyer, L.Perkins, A.Hatano, S.Yoshikai, Y.Pereira, P.Bandeira, A.ELSAID, R.Gomez-Perdiguero, E.Cumano, A.2025-01-09doi:10.1101/2025.01.08.631951Cold Spring Harbor Laboratory Press2025-01-09
<![CDATA[
SifA-mediated Remodeling of the Salmonella-Containing Vacuole Prevents Bacterial Dormancy by Promoting Nutrient Accessibility
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https://biorxiv.org/cgi/content/short/2025.01.08.631959v1?rss=1"
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]]>Valenzuela, C.Rodriguez, F. J. G.Mazza, T.Gil, M.Dotsenko, K.Luk, C. H.Enninga, J.2025-01-08doi:10.1101/2025.01.08.631959Cold Spring Harbor Laboratory Press2025-01-08
<![CDATA[
Protein and genomic language models chart a vast landscape of antiphage defenses
]]>
https://biorxiv.org/cgi/content/short/2025.01.08.631966v1?rss=1"
Mordret, E.Herve, A.Vaysset, H.Clabby, T.Tesson, F.Shomar, H.Lavenir, R.Cury, J.Bernheim, A.2025-01-08doi:10.1101/2025.01.08.631966Cold Spring Harbor Laboratory Press2025-01-08
<![CDATA[
Altered RNA-processing provides a mechanistic framework delineating human sex reversal associated with pathogenic variants in the RNA-helicase DHX37
]]>
https://biorxiv.org/cgi/content/short/2025.01.10.632330v1?rss=1"
Elzaiat, M.Talouarn, E.Wankanit, S.Schlick, L.Eozenou, C.Bignon-Topalovic, J.Kornobis, E.Commere, P.-H.Baum, C.Seffer, V.McElreavey, K.Bashamboo, A.2025-01-13doi:10.1101/2025.01.10.632330Cold Spring Harbor Laboratory Press2025-01-13
<![CDATA[
Ontogeny drives stage-specific effects of a Gata1 mutation
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https://biorxiv.org/cgi/content/short/2025.01.15.633164v1?rss=1"
Sommer, A.Fischer, S.Freyer, L.Lallemand, Y.Dardenne, P.Gomez-Perdiguero, E.2025-01-16doi:10.1101/2025.01.15.633164Cold Spring Harbor Laboratory Press2025-01-16
<![CDATA[
The essential role of 2,4-dienoyl-CoA reductase for degradation of complex fatty acid mixtures
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https://biorxiv.org/cgi/content/short/2025.01.23.634462v1?rss=1"
Schiaffi, V.Pavoncello, V.Barras, F.Bouveret, E.2025-01-24doi:10.1101/2025.01.23.634462Cold Spring Harbor Laboratory Press2025-01-24
<![CDATA[
Polygenic viral factors enable efficient mosquito-borne transmission of African Zika virus
]]>
https://biorxiv.org/cgi/content/short/2025.01.23.634482v1?rss=1"
Torii, S.Lord, J. S.Lavina, M.Prot, M.Lecuyer, A.Diagne, C. T.Faye, O.Faye, O.Sall, A. A.Bonsall, M. B.Simon-Loriere, E.Montagutelli, X.Lambrechts, L.2025-01-24doi:10.1101/2025.01.23.634482Cold Spring Harbor Laboratory Press2025-01-24
<![CDATA[
Impact of natural transformation on the acquisition of novel genes in bacteria
]]>
https://biorxiv.org/cgi/content/short/2025.01.24.634696v1?rss=1"
Mazzamurro, F.Touchon, M.Charpentier, X.Rocha, E. P. C.2025-01-26doi:10.1101/2025.01.24.634696Cold Spring Harbor Laboratory Press2025-01-26
<![CDATA[
Using cryogenic electron microscopy methods to gain insight into structure and initial host attachment of the flagellotropic bacteriophage 7-7-1
]]>
https://biorxiv.org/cgi/content/short/2025.01.29.635402v1?rss=1"
Noteborn, W. E. M.Ouyang, R.Hoeksma, T.Sidi Mabrouk, A.Esteves, N.Pelt, D. M.Scharf, B. E.Briegel, A.2025-01-29doi:10.1101/2025.01.29.635402Cold Spring Harbor Laboratory Press2025-01-29
<![CDATA[
Extracellular vesicle production and membrane uptake promote repair and antibiotic tolerance in E. coli
]]>
https://biorxiv.org/cgi/content/short/2025.02.03.636191v1?rss=1"
Bos, J.Mazel, D.Mayboroda, O.Commere, P.-H.Abou-Haydar, Y.2025-02-03doi:10.1101/2025.02.03.636191Cold Spring Harbor Laboratory Press2025-02-03
<![CDATA[
The epigenomic landscape of bronchial epithelial cells reveals the establishment of trained immunity
]]>
https://biorxiv.org/cgi/content/short/2025.02.03.636250v1?rss=1"
Bigot, J.Legendre, R.Hamroune, J.Jacques, S.Le Gars, M.Guillot, L.Corvol, H.Hennequin, C.Guitard, J.Coppee, J.-Y.Balloy, V.Chica, C.2025-02-07doi:10.1101/2025.02.03.636250Cold Spring Harbor Laboratory Press2025-02-07
<![CDATA[
Programmed in vivo excision of prophage {varphi}13 is an essential timing device for the Staphylococcus aureus infectious process
]]>
https://biorxiv.org/cgi/content/short/2025.02.04.636441v1?rss=1"
Poupel, O.Kenanian, G.Touqui, L.Abrial, C.Jouvion, G.Msadek, T.Dubrac, S.2025-02-04doi:10.1101/2025.02.04.636441Cold Spring Harbor Laboratory Press2025-02-04
<![CDATA[
Nested parasitism in hypersaline environments: viruses and virus satellites of haloarchaea and their nanosized cellular symbionts
]]>
https://biorxiv.org/cgi/content/short/2025.02.15.638363v1?rss=1"
Zhou, Y.Gutierrez-Preciado, A.Liu, Y.Moreira, D.Yakimov, M. M.Lopez-Garcia, P.Krupovic, M.2025-02-15doi:10.1101/2025.02.15.638363Cold Spring Harbor Laboratory Press2025-02-15
<![CDATA[
Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 variants
]]>
https://biorxiv.org/cgi/content/short/2025.02.24.639860v1?rss=1"
Merkling, S. H.Couderc, E.Crist, A. B.Dabo, S.Daron, J.Jupatanakul, N.Burckbuchler, M.Sismeiro, O.Legendre, R.Pain, A.Varet, H.Jiolle, D.Ayala, D.Paupy, C.Marois, E.Lambrechts, L.2025-02-24doi:10.1101/2025.02.24.639860Cold Spring Harbor Laboratory Press2025-02-24
<![CDATA[
High-Throughput Conjugation Reveals Strain Specific Recombination Patterns Enabling Precise Trait Mapping in Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/2025.02.26.640286v1?rss=1"
Corneloup, T.BELLENGIER, J.Magnan, M.Chavan, A.Gachet, B.Dixit, Z.Pintard, C.Baron, A.Toko, D.Lambert, A.Choudhury, A.Tenaillon, O.2025-02-26doi:10.1101/2025.02.26.640286Cold Spring Harbor Laboratory Press2025-02-26
<![CDATA[
Colorectal Cancer-Associated Streptococcus gallolyticus: A Hidden Diversity Exposed
]]>
https://biorxiv.org/cgi/content/short/2025.02.28.640884v1?rss=1"
Perichon, B.COKELAER, T.TEH, W. K.du Merle, L.Ma, L.Doloy, A.Poyart, C.Givskov, M.Trieu-Cuot, P.Dramsi, S.2025-03-03doi:10.1101/2025.02.28.640884Cold Spring Harbor Laboratory Press2025-03-03
<![CDATA[
RNA2seg: a generalist model for cell segmentation in image-based spatial transcriptomics
]]>
https://biorxiv.org/cgi/content/short/2025.03.03.641259v1?rss=1"
Defard, T.Blondel, A.Coleon, A.Dias de Melo, G.Walter, T.Mueller, F.2025-03-11doi:10.1101/2025.03.03.641259Cold Spring Harbor Laboratory Press2025-03-11
<![CDATA[
Impaired stem cell migration and divisions in Duchenne Muscular Dystrophy revealed by live imaging
]]>
https://biorxiv.org/cgi/content/short/2025.03.13.643016v1?rss=1"
Sarde, L.Letort, G.Varet, H.Laville, V.Fernandes, J.Tajbakhsh, S.Evano, B.2025-03-14doi:10.1101/2025.03.13.643016Cold Spring Harbor Laboratory Press2025-03-14
<![CDATA[
Replication coordination marks the domestication of large extrachromosomal replicons in bacteria
]]>
https://biorxiv.org/cgi/content/short/2025.03.15.643453v1?rss=1"
Czarnecki, J.Lamberioux, M.Skovgaard, O.Bignaud, A.Taib, N.Niault, T.Bourhy, P.Bos, J.Krakowska, E.Bartosik, D.Koszul, R.Marbouty, M.Mazel, D.Val, M.-E.2025-03-15doi:10.1101/2025.03.15.643453Cold Spring Harbor Laboratory Press2025-03-15
<![CDATA[
Z-DNA formation induces the totipotent-like state and primes Zscan4-dependent chromatin compartmentalization
]]>
https://biorxiv.org/cgi/content/short/2025.03.18.643869v1?rss=1"
Shajahan, S.Loe-Mie, Y.Salmon-Legagneur, M.Traboulsi, T.Thierry, A.Dejean, A.Cossec, J.-C.2025-03-19doi:10.1101/2025.03.18.643869Cold Spring Harbor Laboratory Press2025-03-19
<![CDATA[
A metabolism-chromatin axis promotes ribosome heterogeneity in the human malaria parasite
]]>
https://biorxiv.org/cgi/content/short/2025.03.22.644534v1?rss=1"
Baumgarten, S.Couble, J.Vignolini, T.Dore, G.Lombard, B.Loew, D.Richard, M.Buettner, M.Poschet, G.Duenas Sanchez, R.Bryant, J. M.2025-03-22doi:10.1101/2025.03.22.644534Cold Spring Harbor Laboratory Press2025-03-22
<![CDATA[
Mapping regulatory networks underlying Leishmania stage differentiation reveals an essential role for protein degradation in parasite development
]]>
https://biorxiv.org/cgi/content/short/2025.03.24.644963v1?rss=1"
Pescher, P.Douche, T.Giai Gianetto, Q.Druart, K.Kovarova, J.Li, B.Proux, C.Legendre, R.Varet, H.Rajan, K. S.Piel, L.Besse, C.Boland, A.Deleuze, J.-F.Matondo, M.Barrett, M. P.Michaeli, S.Späth, G. F.2025-03-28doi:10.1101/2025.03.24.644963Cold Spring Harbor Laboratory Press2025-03-28
<![CDATA[
Harnessing Diversity Generating Retroelements for in vivo targeted hyper-mutagenesis
]]>
https://biorxiv.org/cgi/content/short/2025.03.24.644984v1?rss=1"
Laurenceau, R.Rochette, P.Lopez-Rodriguez, E.Fan, C.Maire, A.Vittot, P.Cerdas-Mejias, K. M.Bouvier, A.Chrysostomou, T.Bikard, D.2025-03-24doi:10.1101/2025.03.24.644984Cold Spring Harbor Laboratory Press2025-03-24
<![CDATA[
Cross-subgenus hybridization between Leishmania and Sauroleishmania informs on parasite genomic compatibility and transcriptomic adaptation
]]>
https://biorxiv.org/cgi/content/short/2025.03.25.645178v1?rss=1"
Louzada-Flores, V. N.Pescher, P.Cokelaer, T.Rodrigues Ferreira, T.Latrofa, M. S.Mendoza-Roldan, J. A.Otranto, D.Späth, G. F.Louradour, I.2025-03-25doi:10.1101/2025.03.25.645178Cold Spring Harbor Laboratory Press2025-03-25
<![CDATA[
Arm and head domain in highly conserved lipoprotein modification enzyme Lgt determine functional diversity among bacterial pathogens
]]>
https://biorxiv.org/cgi/content/short/2025.03.27.645668v1?rss=1"
Legood, S.Oliveira Paiva, A.Taib, N.Ruffiot, T.Gribaldo, S.Gomperts Boneca, I.Buddelmeijer, N.2025-03-27doi:10.1101/2025.03.27.645668Cold Spring Harbor Laboratory Press2025-03-27
<![CDATA[
N6-methyladenosine primes the malaria parasite for transmission
]]>
https://biorxiv.org/cgi/content/short/2025.03.28.645929v1?rss=1"
Mussgnug, S.Vignolini, T.Couble, J.Chen, P.Farhat, D.Sinha, A.Dore, G.Dupre, D.Lambault, M.Hadj Abed, L.Preiser, P.Dedon, P.Bryant, J.Baumgarten, S.2025-03-28doi:10.1101/2025.03.28.645929Cold Spring Harbor Laboratory Press2025-03-28
<![CDATA[
Deep learning recognises antibiotic modes of action from brightfield images
]]>
https://biorxiv.org/cgi/content/short/2025.03.30.645928v1?rss=1"
Krentzel, D.Kho, K.Petit, J.Mahtal, N.Shorte, S. L.Wehenkel, A. M.Boneca, I. G.Zimmer, C.2025-03-31doi:10.1101/2025.03.30.645928Cold Spring Harbor Laboratory Press2025-03-31
<![CDATA[
Modeling viral and bacterial infections in human lung organotypic systems reveals strain specific host responses
]]>
https://biorxiv.org/cgi/content/short/2025.03.31.644992v1?rss=1"
Faria Fonseca, B.Wong-Ng, J.Connor, M.Mary, H.Kim, M. H.Yim, R.BONDET, V.Michel, V.Strick Marchand, H.Di Santo, J. P.Duffy, D.Hamon, M. A.Sauvonnet, N.Chakrabarti, L. A.Gobaa, S.2025-04-01doi:10.1101/2025.03.31.644992Cold Spring Harbor Laboratory Press2025-04-01
<![CDATA[
In Vivo Dual RNA-Seq uncovers key toxin-like effectors of epithelial barrier disruption and tissue colonization by an extracellular bacterial pathogen
]]>
https://biorxiv.org/cgi/content/short/2025.04.04.647190v1?rss=1"
Giraud-Gatineau, A.Haustant, G.Monot, M.Picardeau, M.BENAROUDJ, N.2025-04-04doi:10.1101/2025.04.04.647190Cold Spring Harbor Laboratory Press2025-04-04
<![CDATA[
The type I and III interferon responses restrict infection with tick-borne orthoflaviviruses through IFI6
]]>
https://biorxiv.org/cgi/content/short/2025.04.06.647422v1?rss=1"
Streicher, F.Kenney, D.Caval, V.Chazal, M.Aicher, S.-M.Gracias, S.Roesch, F.Douam, F.Jouvenet, N.2025-04-06doi:10.1101/2025.04.06.647422Cold Spring Harbor Laboratory Press2025-04-06
<![CDATA[
Differential association of SARS-CoV-2 IgG responses with anti-OC43 IgG in a Senegalese cohort
]]>
https://biorxiv.org/cgi/content/short/2025.04.07.647508v1?rss=1"
60 years) exhibited higher IgG levels against both SARS- CoV-2 and HCoVs. Symptomatic patients had higher IgG levels than asymptomatic individuals, especially for WTS, RBD, S2, and N. Anti-HCoV IgG levels remained stable post-infection, with OC43 peaking at week 3 in symptomatic patients. A positive correlation was found between anti-SARS-CoV- 2 and anti-OC43 IgG in symptomatic patients.
The study highlights persistent SARS-CoV-2 IgG antibodies for up to 6 months and suggests a link between pre-existing HCoV-OC43 immunity and COVID-19 outcomes in Senegal. These findings could help shape future vaccine strategies, considering the influence of circulating HCoVs on long- term protection against SARS-CoV-2.
Author summaryUnderstanding how our immune system responds to SARS-CoV-2, the virus responsible for COVID- 19, is essential for guiding public health countermeasures and informing vaccine development strategies. In our study, we monitored, in COVID-19 patients, the evolution of IgG antibody responses against SARS-CoV-2 structural proteins over a six-month period. Additionally, we examined how previous exposure to common seasonal coronaviruses might influence immune responses to SARS-CoV-2. Conducting this research in an African context is particularly important, as data on immune responses to SARS-CoV-2 in this region are scarce.
Our results provide valuable insights into the complex interplay between immune responses elicited by SARS-CoV-2 and pre-existing immunity from seasonal circulating coronaviruses. These findings enhance our understanding of immune memory and cross-reactivity, two critical factors for assessing long-term protection and optimizing vaccine strategies. By shedding light on the dynamics of antibody responses over time within a sub-Saharan population, our research contributes to the global effort aimed at developing effective interventions against COVID-19 and preparing for future coronavirus outbreaks.
]]>Faye, R.Mbow, A. A.Tall, B.Gaye, A.Ndoye, A. M.Gueye, R.Diallo, D.Faye, F. N.Talla, C.Dia, N.Mbengue, B.Pelleau, S.Niang, M.Seydi, M.Sall, A. A.Taïeb, F.Loucoubar, C.White, M.Poiret, T.Vigan-Womas, I.2025-04-08doi:10.1101/2025.04.07.647508Cold Spring Harbor Laboratory Press2025-04-08
<![CDATA[
Identification of Monotonically Classifying Pairs of Genes for Ordinal Disease Outcomes
]]>
https://biorxiv.org/cgi/content/short/2025.04.10.643941v1?rss=1"
Fourquet, O.Afenteva, D.Zhang, K.Hautaniemi, S.Krejca, M.Doerr, C.Schwikowski, B.2025-04-10doi:10.1101/2025.04.10.643941Cold Spring Harbor Laboratory Press2025-04-10
<![CDATA[
Vector Competence of Temperate and Tropical Mosquito Species for Babanki virus
]]>
https://biorxiv.org/cgi/content/short/2025.04.14.648682v1?rss=1"
Ban, M.Geolier, V.Ferquel, E.Faye, M.Diagne, M. M.Ndiaye, E. H.Fall, G.Diallo, M.Lavillette, D.Choumet, V.2025-04-14doi:10.1101/2025.04.14.648682Cold Spring Harbor Laboratory Press2025-04-14
<![CDATA[
The Rab32 small GTPase is required for efficient cross-priming of CD8+ T cellsagainst cell-associated antigens by XCR1+ type 1 DCs in vivo.
]]>
https://biorxiv.org/cgi/content/short/2025.05.03.652057v1?rss=1"
Tandon, N.Gutierrez-Martinez, E.Bourdely, P.Anselmi, G.Denisot, J.Gerber, Y.Helft, J.Bens, M.Saveanu, L.Guermonprez, P.2025-05-08doi:10.1101/2025.05.03.652057Cold Spring Harbor Laboratory Press2025-05-08
<![CDATA[
Empowering multitrait brain phenotypes GWAS
]]>
https://biorxiv.org/cgi/content/short/2025.05.04.652120v1?rss=1"
Auvergne, A.Traut, N.Julienne, H.Frouin, A.Toro, R.Aschard, h.2025-05-05doi:10.1101/2025.05.04.652120Cold Spring Harbor Laboratory Press2025-05-05
<![CDATA[
Alignment-free integration of single-nucleus ATAC-seq across species with sPYce
]]>
https://biorxiv.org/cgi/content/short/2025.05.07.652648v1?rss=1"
Zeitler, L.Berthelot, C.2025-05-10doi:10.1101/2025.05.07.652648Cold Spring Harbor Laboratory Press2025-05-10
<![CDATA[
Direct measurements of active forces and material properties unveil the active mechanics of early embryogenesis
]]>
https://biorxiv.org/cgi/content/short/2025.05.11.653307v1?rss=1"
Michaut, A.Chamolly, A.ALEGRIA, O.Phan, C.Corson, F.Gros, J.2025-05-12doi:10.1101/2025.05.11.653307Cold Spring Harbor Laboratory Press2025-05-12
<![CDATA[
Provision of Preferred Nutrients to Macrophages Enables Salmonella to Replicate Intracellularly Without Relying on Type III Secretion Systems
]]>
https://biorxiv.org/cgi/content/short/2025.05.15.653970v1?rss=1"
Garcia-Rodriguez, F.-J.Valenzuela, C.Bernal-Bayard, J.Escoll, P.2025-05-15doi:10.1101/2025.05.15.653970Cold Spring Harbor Laboratory Press2025-05-15
<![CDATA[
Live imaging and functional characterization of the avian hypoblast redefine the mechanisms of primitive streak induction
]]>
https://biorxiv.org/cgi/content/short/2025.05.15.654239v1?rss=1"
Villedieu, A.Alegria-Prevot, O.Phan, C.Ieda, Y.Corson, F.Gros, J.2025-05-17doi:10.1101/2025.05.15.654239Cold Spring Harbor Laboratory Press2025-05-17
<![CDATA[
Intra-tumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ DC1 infiltration and activates anti-tumor immunity
]]>
https://biorxiv.org/cgi/content/short/2025.05.19.654717v1?rss=1"
Gorline, L.Rosa do Carmo, F.Bourdely, P.Borneres, J.Vaudiau, N.Semervil, A.Vetillard, M.Ok, A.Fiquet, O.Andrade, M.Theobald, H.Collin, M.Calmette, J.Anselmi, G.Fico, F.Ginhoux, F.Saveanu, L.Helft, J.Dalod, M.Dusseaux, M.Di Santo, J. P.Hugues, S.Guermonprez, P.2025-05-23doi:10.1101/2025.05.19.654717Cold Spring Harbor Laboratory Press2025-05-23
<![CDATA[
Impacts of wastewater treatment and the exposome on antibiotic resistance gene dynamics: Insights from Guadeloupe, a French Caribbean Island
]]>
https://biorxiv.org/cgi/content/short/2025.05.31.657145v1?rss=1"
Alexa, M.Kovacevic, A.Pimenta, M.Batantou Mabandza, D.Ahmed, I.Breurec, S.DAGOT, C.Huynh, B.-T.Opatowski, L.2025-05-31doi:10.1101/2025.05.31.657145Cold Spring Harbor Laboratory Press2025-05-31
<![CDATA[
The geometry of cortical sound processing in slow wave sleep
]]>
https://biorxiv.org/cgi/content/short/2025.06.13.658070v1?rss=1"
Muller, A.Filipchuk, A.Bagur, S.Bathellier, B.2025-06-14doi:10.1101/2025.06.13.658070Cold Spring Harbor Laboratory Press2025-06-14
<![CDATA[
A connection between two ancient and essential cellular processes, iron-sulfur protein biogenesis and fatty acid synthesis, in Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/2025.06.16.659903v1?rss=1"
Fakroun, S.Bouvier, G.Libiad, M.Sechet, E.Bouveret, E.Barras, F.Dubrac, S.2025-06-16doi:10.1101/2025.06.16.659903Cold Spring Harbor Laboratory Press2025-06-16
<![CDATA[
Hicberg: Reconstruction of contact signals from repeated elements
]]>
https://biorxiv.org/cgi/content/short/2025.06.20.660295v1?rss=1"
Gradit, S.Ortion, S.Larrous, P.Delouis, M.Koszul, R.Cournac, A.2025-06-25doi:10.1101/2025.06.20.660295Cold Spring Harbor Laboratory Press2025-06-25
<![CDATA[
Life identification number (LIN) codes for the genomic taxonomy of Corynebacterium diphtheriae strains
]]>
https://biorxiv.org/cgi/content/short/2025.06.20.660692v1?rss=1"
400 SLs and >1,000 GCs. For epidemiological purposes, five shallow-level thresholds (8, 4, 2 ,1, and 0 allelic mismatches were defined, completing the 10-level LIN code taxonomy. We illustrate LIN codes applicability to investigate the genetic diversity and transmission chains of relevant clusters, such as SL8 (the 1990s ex-USSR outbreak) or SL384 (involved in outbreaks in Yemen and Europe).
ConclusionsThe cgMLST-based LIN code system provides a stable genomic taxonomy for strains of C. diphtheriae, C. rouxii and C. belfantii. By defining ten hierarchical levels of resolution, this system effectively captures its phylogenetic diversity, facilitating population biology research and epidemiological surveillance. The public availability of this system from the BIGSdb-Pasteur platform provides a standardized framework for diphtheria genomic epidemiology with potential to harmonize global surveillance of the resurgence of diphtheria.
]]>Delgado-Blas, J.Rethoret-Pasty, M.Brisse, S.2025-06-21doi:10.1101/2025.06.20.660692Cold Spring Harbor Laboratory Press2025-06-21
<![CDATA[
α-Synuclein aggregates induce mitochondrial damage and trigger innate immunity to drive neuron-microglia communication
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https://biorxiv.org/cgi/content/short/2025.06.23.661105v1?rss=1"
Chakraborty, R.Maya, S.Testa, V.Montero-Munoz, J.Nonaka, T.Hasegawa, M.Consiglio, A.Zurzolo, C.2025-06-24doi:10.1101/2025.06.23.661105Cold Spring Harbor Laboratory Press2025-06-24
<![CDATA[
Intratumoral Heterogeneity of Vimentin Modulates Nuclear Mechanotransduction, DNA Damage Response and Cancer Cell Survival
]]>
https://biorxiv.org/cgi/content/short/2025.06.27.661506v1?rss=1"
Infante, E.Terriac, E.Gelin, M.Siegfried, H.Pereira, D.Roca, V.Varet, H.Khalilian, S.Rietveld, R.Asnacios, A.van Bodegraven, E. J.Etienne-Manneville, S.2025-06-28doi:10.1101/2025.06.27.661506Cold Spring Harbor Laboratory Press2025-06-28
<![CDATA[
N-Cadherin/α-Catenin Drive Adhesion and Actin Regulation to Orchestrate Tunneling Nanotube Formation
]]>
https://biorxiv.org/cgi/content/short/2025.06.27.661900v1?rss=1"
Zurzolo, C.Belian, S.Pepe, A.Notario Manzano, R.Sartori-Rupp, A.Brou, C.2025-06-27doi:10.1101/2025.06.27.661900Cold Spring Harbor Laboratory Press2025-06-27
<![CDATA[
Mechanistic insights into the allosteric regulation of cell wall hydrolase RipA in Mycobacterium tuberculosis.
]]>
https://biorxiv.org/cgi/content/short/2025.06.28.662095v1?rss=1"
Carloni, G.Gaday, Q.Petit, J.Martinez, M.Megrian, D.Sogues, A.Ben Assaya, M.Kakonyi, M.Haouz, A.Alzari, P. M.Wehenkel, A. M.2025-06-29doi:10.1101/2025.06.28.662095Cold Spring Harbor Laboratory Press2025-06-29
<![CDATA[
Polygenetic Determinants of Azole Resistance, Tolerance, and Heteroresistance in Candida albicans
]]>
https://biorxiv.org/cgi/content/short/2025.06.29.662174v1?rss=1"
Schutz, K.Gautier, C.Maufrais, C.Sertour, N.Bougnoux, M.-E.D'Enfert, C.Evans, L. M.Smith, S. D.Ene, I. V.2025-06-29doi:10.1101/2025.06.29.662174Cold Spring Harbor Laboratory Press2025-06-29
<![CDATA[
Tinnitus perception is linked to arousal system dysfunction
]]>
https://biorxiv.org/cgi/content/short/2025.07.01.662596v1?rss=1"
Hobeika, L.Masson, R.Dupont, S.Londero, A.Samson, S.2025-07-02doi:10.1101/2025.07.01.662596Cold Spring Harbor Laboratory Press2025-07-02
<![CDATA[
Linking genomic evolutionary transitions to ecological phenotypic adaptations in Spirochaetes
]]>
https://biorxiv.org/cgi/content/short/2025.07.04.663154v1?rss=1"
HUETE, S. G.COULLIN, K.CHAPEAUBLANC, E.TORCHET, R.BENAROUDJ, N.PICARDEAU, M.2025-07-04doi:10.1101/2025.07.04.663154Cold Spring Harbor Laboratory Press2025-07-04
<![CDATA[
Morphological plasticity of endophytic Chitinophaga pinensis
]]>
https://biorxiv.org/cgi/content/short/2025.07.09.663833v1?rss=1"
Liedtke, J.Rodenburg, F.Du, C.Zhang, L.van Wezel, G.Briegel, A.2025-07-09doi:10.1101/2025.07.09.663833Cold Spring Harbor Laboratory Press2025-07-09
<![CDATA[
HTRF-based identification of small molecules targeting SARS-CoV-2 E protein interaction with ZO-1 PDZ2
]]>
https://biorxiv.org/cgi/content/short/2025.07.16.665136v1?rss=1"
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org.highwire.dtl.DTLVardef@1f900bcorg.highwire.dtl.DTLVardef@9f470aorg.highwire.dtl.DTLVardef@f0ec19org.highwire.dtl.DTLVardef@11c9115_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>ALVAREZ, F.Larrous, F.MECHALY, A.Bardiaux, B.GOOR, Q.Haouz, A.seon-meniel, b.Alves de sousa, R.BOURG, S.FIGADERE, B.Wolff, N.Lehmann, H.Caillet-Saguy, C.2025-07-16doi:10.1101/2025.07.16.665136Cold Spring Harbor Laboratory Press2025-07-16
<![CDATA[
Principles of neocortical organisation and behaviour in primates
]]>
https://biorxiv.org/cgi/content/short/2025.07.17.665410v1?rss=1"
Heuer, K.Traut, N.Aristide, L.Alavi, S. F.Herbin, M.Mars, R. B.Mylapalli, R.Najafipashaki, S.Sakai, T.Santin, M. D.Borrell, V.Toro, R.2025-07-22doi:10.1101/2025.07.17.665410Cold Spring Harbor Laboratory Press2025-07-22
<![CDATA[
HTRA3 protease-chaperone stabilizes cathepsin B for mitochondrial POLG1 depletion in human cell ageing
]]>
https://biorxiv.org/cgi/content/short/2025.07.21.647696v1?rss=1"
Fernandez Molina, C.Chatre, L.Montagne, B.Salles, A.Sarasin, A.Crochemore, C.Ricchetti, M.2025-07-21doi:10.1101/2025.07.21.647696Cold Spring Harbor Laboratory Press2025-07-21
<![CDATA[
Intrinsic differences in hamster and mouse macrophage biology correlate with susceptibility to L. donovani infection
]]>
https://biorxiv.org/cgi/content/short/2025.08.01.668127v1?rss=1"
Jenkins, P.Danckaert, A.Cokelaer, T.Mahtal, N.Pescher, P.Späth, G. F.2025-08-02doi:10.1101/2025.08.01.668127Cold Spring Harbor Laboratory Press2025-08-02
<![CDATA[
Tunneling Nanotube-like Connections in the Developing Cerebellum: Distinct from Cytokinetic and Intercellular Bridges
]]>
https://biorxiv.org/cgi/content/short/2025.08.11.669634v1?rss=1"
RAKOTOBE, M.Virmani, G.Liu, S.Kaddour, G.Mendoza, N. D.Livet, J.Cathala, L.Zurzolo, C.2025-08-14doi:10.1101/2025.08.11.669634Cold Spring Harbor Laboratory Press2025-08-14
<![CDATA[
Mutant CHCHD10 disrupts cytochrome c oxidation and activates retrograde signaling in a model of cardiomyopathy.
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https://biorxiv.org/cgi/content/short/2025.08.18.668848v1?rss=1"
Campos-Ribeiro, M. A.Donnarumma, E.Nolte, H.Cobine, P.Vimont, E.Milenkovic, D.Hernandez-Camacho, J. D.Langa Vives, F.Kornobis, E.Penard, E.Langer, T.Paquis-Flucklinger, V.Wai, T.2025-08-18doi:10.1101/2025.08.18.668848Cold Spring Harbor Laboratory Press2025-08-18
<![CDATA[
Functional dissection of Wag31 domains for septal recruitment and polar distribution during the cell cycle
]]>
https://biorxiv.org/cgi/content/short/2025.08.21.671543v1?rss=1"
Petit, J.Megrian, D.Martinez, M.Sogues, A.de Sousa-d'Auria, C.Ben Assaya, M.THOUVENOT, C.Lesur, E.Bourdreux, Y.Bayan, N.Alzari, P. M.Wehenkel, A. M.2025-08-21doi:10.1101/2025.08.21.671543Cold Spring Harbor Laboratory Press2025-08-21
<![CDATA[
Polyfunctionality of broadly reactive non-neutralizing SARS-CoV-2 RBD antibodies
]]>
https://biorxiv.org/cgi/content/short/2025.08.26.672080v1?rss=1"
Rosenbaum, P.Planchais, C.Bruel, T.Beretta, M.Bolland, W.Staropoli, I.Guivel-Benhassine, F.Schwartz, O.Mouquet, H.2025-08-26doi:10.1101/2025.08.26.672080Cold Spring Harbor Laboratory Press2025-08-26
<![CDATA[
ICP1 bacteriophage treatment antagonizes colonization of the zebrafish larval intestine by Vibrio cholerae
]]>
https://biorxiv.org/cgi/content/short/2025.09.01.673471v1?rss=1"
Sidi Mabrouk, A.Depelteau, J. S.Foini, C.Kempff, A.Jonker, S.Brenzinger, S.Limpens, R. W. A. L.Majrouh, M.Meijer, A. H.Briegel, A.2025-09-01doi:10.1101/2025.09.01.673471Cold Spring Harbor Laboratory Press2025-09-01
<![CDATA[
Cellular NAD+ availability and redox state constrain developmental speed in the Drosophila eye
]]>
https://biorxiv.org/cgi/content/short/2025.09.02.673715v1?rss=1"
veits, n.Guo, Y.He, J.Mazouni, K.Nemazanyy, I.Bres, M.picciotto, c.Mestdagh, C.Yan, Y.Schweisguth, F.2025-09-02doi:10.1101/2025.09.02.673715Cold Spring Harbor Laboratory Press2025-09-02
<![CDATA[
Complex-I Preserves Mitochondrial Polarization during Infection of Human Macrophages by Secretion-competent Bacteria
]]>
https://biorxiv.org/cgi/content/short/2025.09.04.674018v1?rss=1"
Garcia-Rodriguez, F.-J.Martinez-Oca, P.Buchrieser, C.Escoll, P.2025-09-04doi:10.1101/2025.09.04.674018Cold Spring Harbor Laboratory Press2025-09-04
<![CDATA[
Spatio-temporal factors shape mosquito virome diversity and composition in a host and virus phylogeny-dependent manner
]]>
https://biorxiv.org/cgi/content/short/2025.09.05.674492v1?rss=1"
Koh, C.Butkovic, A.Frangeul, L.Blanc, H.Gibaud, A.Henrion Lacritick, A.Chitale, R.Boyer, S.Duchemin, J.-B.Dussart, P.Girod, R.Grau, N.Ngoagouni, C.Saleh, M.-C.2025-09-05doi:10.1101/2025.09.05.674492Cold Spring Harbor Laboratory Press2025-09-05
<![CDATA[
Post-translational acylation drives folding and activity of the CyaA bacterial toxin.
]]>
https://biorxiv.org/cgi/content/short/2025.09.11.673628v1?rss=1"
Leger, C.Hoff, S. E.Scilironi, G.Abettan, A.Shrestha, R.Frangieh, J.Deruelle, V.Carvalho, N.Raoux-Barbot, D.Duclert-Savatier, N.Bardiaux, B.Brier, S.Bontems, F.Pehau-Arnaudet, G.Ladant, D.Monticelli, L.Bonomi, M.CHENAL, A.2025-09-12doi:10.1101/2025.09.11.673628Cold Spring Harbor Laboratory Press2025-09-12
<![CDATA[
Sphingolipid Homeostasis, Mitochondrial Activity, and PKA Signaling Drive an Azole-Tolerant State
]]>
https://biorxiv.org/cgi/content/short/2025.09.12.675915v1?rss=1"
Gautier, C.Maciel, E. I.Maufrais, C.Lyons, N.Kawar, N.Bibi, C.Eickmann, C.Rosenberg, A.Dasilva, D.Fidelis Viera De Sa, N.Del Poeta, M.Bennett, R. J.Berman, J.Ene, I. V.2025-09-12doi:10.1101/2025.09.12.675915Cold Spring Harbor Laboratory Press2025-09-12
<![CDATA[
Nitrate-responsive Mycobacterial Intracytoplasmic Membranes dampen Inflammation during Mycobacterium tuberculosis Infection
]]>
https://biorxiv.org/cgi/content/short/2025.09.17.676823v1?rss=1"
Keck, C.Tachon, S.Sayes, F.Musiani, D.Gianetto, Q. G.Matondo, M.Vos, M.Brosch, R.Enninga, J.2025-09-17doi:10.1101/2025.09.17.676823Cold Spring Harbor Laboratory Press2025-09-17
<![CDATA[
Improved Immune Responses and Tuberculosis Protection by Aerosol Vaccination with recombinant BCG expressing ESX-1 from Mycobacterium marinum
]]>
https://biorxiv.org/cgi/content/short/2025.09.18.677039v1?rss=1"
Sayes, F.Frigui, W.Pawlik, A.Tillier, C.Tichit, M.Hardy, D.Brosch, R.2025-09-18doi:10.1101/2025.09.18.677039Cold Spring Harbor Laboratory Press2025-09-18
<![CDATA[
NK cells undergo transcriptional and functional reprogramming following Streptococcus pneumoniae infection
]]>
https://biorxiv.org/cgi/content/short/2025.09.19.677332v1?rss=1"
Torne, J.Chica, C.Camarasa, T.Jagla, B.Diaz Enes, M.Zellner, A.Mella, S.Libri, V.Hamon, M. A.2025-09-21doi:10.1101/2025.09.19.677332Cold Spring Harbor Laboratory Press2025-09-21
<![CDATA[
Nuclear Argonaute HRDE-1 Sustains Chromatin-Independent Transcriptional Silencing and Epigenetic Inheritance
]]>
https://biorxiv.org/cgi/content/short/2025.09.24.678226v1?rss=1"
Rojas, A. M.Chervova, A.Bourdon, L.Jayaraj, J.Morao, A. K.Feudjio, O.Illic, S.Capurso, S.Quarato, P.Ovieve, J.Cecere, G.2025-09-24doi:10.1101/2025.09.24.678226Cold Spring Harbor Laboratory Press2025-09-24
<![CDATA[
A targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti
]]>
https://biorxiv.org/cgi/content/short/2025.09.28.679043v1?rss=1"
Daron, J.Lecuyer, A.Ma, L.Marzooghi, P.Breban, M. I.Kryrylos, P.Donovan-Banfield, I.Redmond, S. N.LAMBRECHTS, L.2025-09-30doi:10.1101/2025.09.28.679043Cold Spring Harbor Laboratory Press2025-09-30
<![CDATA[
Entry, replication and innate immunity evasion of BANAL-236, a SARS-CoV-2-related bat virus, in Rhinolophus and human cells
]]>
https://biorxiv.org/cgi/content/short/2025.09.29.679146v1?rss=1"
Gracias, S.Donaire-Carpio, S.Vuillier, F.Le Seach, E.Vendramini, L.Moundib, A.Rutkowska, M.Cupic, A.Juste, J.Temmam, S.Donati, F.Martinez-Romero, C.Morel, N.SCHWARTZ, O.Krogan, N.Miorin, L.Demeret, C.Roingeard, P.Munier, S.Batra, J.Garcia-Sastre, A.Caval, v.Jouvenet, N.2025-09-29doi:10.1101/2025.09.29.679146Cold Spring Harbor Laboratory Press2025-09-29
<![CDATA[
Characterization of the dual functions of Leishmania CK1.2 in both the parasite and the macrophage using integrated proteomics and spatial mapping
]]>
https://biorxiv.org/cgi/content/short/2025.09.30.679250v1?rss=1"
Martel, D.Leclercq, O.Dingli, F.Laigle, V.Loew, D.Spaeth, G. F.RACHIDI, N.2025-09-30doi:10.1101/2025.09.30.679250Cold Spring Harbor Laboratory Press2025-09-30
<![CDATA[
A Chryseobacterium massiliae pore-forming MACPF domain protein mediates intra and interspecies competition against Bacteroides
]]>
https://biorxiv.org/cgi/content/short/2025.10.02.679979v1?rss=1"
AUDRAIN, B.PEREZ-PASCUAL, D.THIRIET-RUPERT, S.BERNAL-BAYARD, J.STRESSMANN, F.GHIGO, J.-M.2025-10-02doi:10.1101/2025.10.02.679979Cold Spring Harbor Laboratory Press2025-10-02
<![CDATA[
Macrodomain ADP-ribose binding but not ADP-ribosylhydrolase activity is critical for chikungunya virus infection of Aedes mosquitoes
]]>
https://biorxiv.org/cgi/content/short/2025.10.09.681498v1?rss=1"
Bardossy, E. S.Bergmann, L.Lacritick, A. H.Nigg, J.Correy, G. J.Ashworth, A.Fraser, J. S.Saleh, M. C.2025-10-09doi:10.1101/2025.10.09.681498Cold Spring Harbor Laboratory Press2025-10-09
<![CDATA[
Met-Vision stratifies single cell metabolism revealing coexisting energetic states in tissue macrophages redistributed by inflammation
]]>
https://biorxiv.org/cgi/content/short/2025.10.10.681557v1?rss=1"
Lecourieux, A.Bardou, M.Garcia, Z.Bousso, P.2025-10-11doi:10.1101/2025.10.10.681557Cold Spring Harbor Laboratory Press2025-10-11
<![CDATA[
napariTFM: An Open-Source Tool for Traction ForceMicroscopy and Monolayer Stress Microscopy
]]>
https://biorxiv.org/cgi/content/short/2025.10.14.682385v1?rss=1"
Ruppel, A.Woerthmueller, D.Balland, m.Fagotto, F.2025-10-15doi:10.1101/2025.10.14.682385Cold Spring Harbor Laboratory Press2025-10-15
<![CDATA[
Fluke-borne viruses are a risk factor for diseases caused by carcinogenic trematodes
]]>
https://biorxiv.org/cgi/content/short/2025.10.22.683923v1?rss=1"
Chaiyadet, S.Roblin, T.Fauchois, A.Temmam, S.Hing, D.Jacquemet, E.Bigot, T.Li, B.Kende, J.Capai, L.Sotillo, J.Thewarach, L.Goyard, S.Hardy, D.Rose, T.Loukas, A.Brindley, P. J.Sripa, B.Dheilly, N. M.2025-10-22doi:10.1101/2025.10.22.683923Cold Spring Harbor Laboratory Press2025-10-22
<![CDATA[
Comparison of multiple transcriptomes exposes unified and divergent features of quiescent and activated skeletal muscle stem cells
]]>
https://biorxiv.org/cgi/content/short/219998v1?rss=1"
Pietrosemoli, N.Mella, S.Yennek, S.Baghdadi, M.Sakai, H.Sambasivan, R.Pala, F.DI GIROLAMO, D.Tajbakhsh, S.2017-11-15doi:10.1101/219998Cold Spring Harbor Laboratory Press2017-11-15
<![CDATA[
VarExp: Estimating variance explained by Genome-Wide GxE summary statistics
]]>
https://biorxiv.org/cgi/content/short/224634v1?rss=1"
Laville, V.Bentley, A.Prive, F.Zhu, X.Gauderman, W.Winkler, T.Province, M.Rao, D.Aschard, H.CHARGE Gene-Lifestyle Interactions Working Group,2017-11-24doi:10.1101/224634Cold Spring Harbor Laboratory Press2017-11-24
<![CDATA[
Host range expansion and genetic plasticity drive the trade-off between integrative and extrachromosomal mobile genetic elements
]]>
https://biorxiv.org/cgi/content/short/250266v1?rss=1"
Cury, J.Oliveira, P.de la Cruz, F.Rocha, E.2018-01-18doi:10.1101/250266Cold Spring Harbor Laboratory Press2018-01-18
<![CDATA[
Generating genomic platforms to study Candida albicans pathogenesis
]]>
https://biorxiv.org/cgi/content/short/261628v1?rss=1"
Legrand, M.Bachellier-Bassi, S.Lee, K. K.Chaudhari, Y.Tournu, H.Arbogast, L.Boyer, H.Chauvel, M.Cabral, V.Maufrais, C.Nesseir, A.Maslanka, I.Permal, E.Rossignol, T.Walker, L. A.Zeidler, U.Znaidi, S.Schoeters, F.Majgier, C.Julien, R. A.Ma, L.Tichit, M.Bouchier, C.Van Dijck, P.Munro, C. A.d'Enfert, C.2018-02-08doi:10.1101/261628Cold Spring Harbor Laboratory Press2018-02-08
<![CDATA[
Influenza A virus environmental persistence is driven by the hemagglutinin and the neuraminidase
]]>
https://biorxiv.org/cgi/content/short/268722v1?rss=1"
Labadie, T.Batejat, C.Manuguerra, J.-C.Leclercq, I.2018-02-22doi:10.1101/268722Cold Spring Harbor Laboratory Press2018-02-22
<![CDATA[
Biallelic Mutations in LRRC56 encoding a protein associated with intraflagellar transport, cause mucociliary clearance and laterality defects
]]>
https://biorxiv.org/cgi/content/short/288852v1?rss=1"
Bonnefoy, S.Watson, C.Kernohan, K.Lemos, M.Hutchinson, S.Poulter, J.Crinion, L.O'Callaghan, C.Hirst, R.Rutman, A.Huang, L.Hartley, T.Grynspan, D.Moya, E.Li, C.Carr, I.Bonthron, D.Leroux, M.Care4Rare Canada Consortium,Boycott, K.Bastin, P.Sheridan, E.2018-03-27doi:10.1101/288852Cold Spring Harbor Laboratory Press2018-03-27
<![CDATA[
Modelling bacteria-phage interactions driving predation and horizontal gene transfer
]]>
https://biorxiv.org/cgi/content/short/291328v1?rss=1"
Sousa, J. M. d.Alsaadi, A.Haaber, J.Ingmer, H.Rocha, E. P. C.2018-03-30doi:10.1101/291328Cold Spring Harbor Laboratory Press2018-03-30
<![CDATA[
Haemophilus to meningococci transfer of beta-lactamase
]]>
https://biorxiv.org/cgi/content/short/308056v1?rss=1"
Hong, E.Deghmane, A.-E.Taha, M.-K.2018-05-09doi:10.1101/308056Cold Spring Harbor Laboratory Press2018-05-09
<![CDATA[
Genome-wide CRISPR-Cas9 screen in E. coli identifies design rules for efficient targeting
]]>
https://biorxiv.org/cgi/content/short/308148v1?rss=1"
Gutierrez Soriano, B.Wong Ng, J.Cui, L.Becavin, C.Bikard, D.2018-04-30doi:10.1101/308148Cold Spring Harbor Laboratory Press2018-04-30
<![CDATA[
Genome-wide CRISPR-dCas9 screens in E. coli identify essential genes and phage host factors
]]>
https://biorxiv.org/cgi/content/short/308916v1?rss=1"
Rousset, F.Cui, L.Siouve, E.Depardieu, F.Bikard, D.2018-04-26doi:10.1101/308916Cold Spring Harbor Laboratory Press2018-04-26
<![CDATA[
Intermediate filaments control collective migration by restricting traction forces and sustaining cell-cell contacts
]]>
https://biorxiv.org/cgi/content/short/328609v1?rss=1"
De Pascalis, C.Perez-Gonzalez, C.Seetharaman, S.Boeda, B.Vianay, B.Burute, M.Leduc, C.Borghi, N.Trepat, X.Etienne-Manneville, S.2018-05-23doi:10.1101/328609Cold Spring Harbor Laboratory Press2018-05-23
<![CDATA[
Genetic diversity in two Plasmodium vivax protein ligands for reticulocyte invasion
]]>
https://biorxiv.org/cgi/content/short/328757v1?rss=1"
Roesch, C.Popovici, J.Bin, S.Run, V.Kim, S.Ramboarina, S.Rakotomalala, E.Rakotoarison, R. L.Rasoloharimanana, T.Andriamanantena, Z.Kumar, A.Guillotte-Blisnick, M.Huon, C.Serre, D.Chitnis, C. E.Vigan-Womas, I.Menard, D.2018-05-22doi:10.1101/328757Cold Spring Harbor Laboratory Press2018-05-22
<![CDATA[
Bidirectional intraflagellar transport is restricted to only two microtubule doublets in the trypanosome flagellum
]]>
https://biorxiv.org/cgi/content/short/329300v1?rss=1"
Bertiaux, E.Mallet, A.Fort, C.Blisnick, T.Bonnefoy, S.Jung, J.Lemos, M.Marco, S.Vaughan, S.Trepout, S.Tinevez, J.-Y.Bastin, P.2018-05-23doi:10.1101/329300Cold Spring Harbor Laboratory Press2018-05-23
<![CDATA[
Worldwide survey reveals lower susceptibility of African Aedes aegypti mosquitoes to diverse strains of Zika virus
]]>
https://biorxiv.org/cgi/content/short/342741v1?rss=1"
Aubry, F.Martynow, D.Baidaliuk, A.Merkling, S. H.Dickson, L. B.Romero-Vivas, C. M.Vega-Rua, A.Dusfour, I.Jiolle, D.Paupy, C.Mayanja, M. N.Lutwama, J. J.Kohl, A.Duong, V.Ponlawat, A.Cao-Lormeau, V.-M.Jarman, R. G.Diagne, C. T.Faye, O.Faye, O.Sall, A. A.Lambrechts, L.2018-06-10doi:10.1101/342741Cold Spring Harbor Laboratory Press2018-06-10
<![CDATA[
Identification of Klebsiella pneumoniae complex members using MALDI-TOF mass spectrometry
]]>
https://biorxiv.org/cgi/content/short/350579v1?rss=1"
Rodrigues, C.Passet, V.Brisse, S.2018-06-19doi:10.1101/350579Cold Spring Harbor Laboratory Press2018-06-19
<![CDATA[
Timed collinear activation of Hox genes during gastrulation controls the avian forelimb position
]]>
https://biorxiv.org/cgi/content/short/351106v1?rss=1"
Moreau, C.Caldarelli, P.Rocancourt, D.Roussel, J.Denans, N.Pourquie, O.Gros, J.2018-06-20doi:10.1101/351106Cold Spring Harbor Laboratory Press2018-06-20
<![CDATA[
High proportion of multiple copies of Plasmodium falciparum Plasmepsin-2 gene in African isolates: Is piperaquine resistance emerging in Africa?
]]>
https://biorxiv.org/cgi/content/short/361204v1?rss=1"
30%).nnOur findings sharply contrast with the recent description of increased sensitivity to PPQ of Ugandan parasite isolates. This emphasizes the necessity to decipher the genetic background associated with PPQ resistance in Africa by investigating in vitro susceptibilities to PPQ of isolates with multiple copies of the Pfpm2 gene and the urgent need to assess the risk of development of PPQ resistance, along with the efficacy of both current frontline therapies and new antimalarial combinations.
]]>Leroy, D.Macintyre, F.Adamy, M.Laurijssens, B.Klopper, R.Khim, N.Legrand, E.Wells, T.Menard, D.2018-07-03doi:10.1101/361204Cold Spring Harbor Laboratory Press2018-07-03
<![CDATA[
Both rare and common genetic variants contribute to autism in the Faroe Islands
]]>
https://biorxiv.org/cgi/content/short/363853v1?rss=1"
Leblond, C.Cliquet, F.Carton, C.Huguet, G.Mathieu, A.Kergrohen, T.Buratti, J.Lemiere, N.Cuisset, L.Bienvenu, T.Boland, A.Deleuze, J.-F.Stora, T.Biskupstoe, R.Halling, J.Andorsdottir, G.Billstedt, E.Gillberg, C.Bourgeron, T.2018-07-06doi:10.1101/363853Cold Spring Harbor Laboratory Press2018-07-06
<![CDATA[
The molecular logic of Nanog-induced self-renewal
]]>
https://biorxiv.org/cgi/content/short/374371v1?rss=1"
Heurtier, V.Owens, N.Gonzalez, I.Mueller, F.Proux, C.Mornico, D.Clerc, P.Dubois, A.Navarro, P.2018-07-23doi:10.1101/374371Cold Spring Harbor Laboratory Press2018-07-23
<![CDATA[
Evolution of neocortical folding: A phylogenetic comparative analysis of MRI from 33 primate species
]]>
https://biorxiv.org/cgi/content/short/379750v1?rss=1"
Heuer, K.Gulban, O. F.Bazin, P.-L.Osoianu, A.Valabregue, R.Santin, M.Herbin, M.Toro, R.2018-07-30doi:10.1101/379750Cold Spring Harbor Laboratory Press2018-07-30
<![CDATA[
Adhesion to nanofibers drives cell membrane remodeling through 1D wetting
]]>
https://biorxiv.org/cgi/content/short/393744v1?rss=1"
Charles-Orszag, A.Tsai, F.-C.Bonazzi, D.Manriquez, V.Sachse, M.Mallet, A.Salles, A.Melican, K.Staneva, R.Bertin, A.Millien, C.Goussard, S.Lafaye, P.Shorte, S.Piel, M.Krijnse-Locker, J.Brochard-Wyart, F.Bassereau, P.Dumenil, G.2018-08-16doi:10.1101/393744Cold Spring Harbor Laboratory Press2018-08-16
<![CDATA[
A tensile ring drives tissue flows to shape the gastrulating amniote embryo
]]>
https://biorxiv.org/cgi/content/short/412767v1?rss=1"
Saadaoui, M.Corson, F.Rocancourt, D.Roussel, J.Gros, J.2018-09-10doi:10.1101/412767Cold Spring Harbor Laboratory Press2018-09-10
<![CDATA[
Candida albicans biofilms are generally devoid of persister cells
]]>
https://biorxiv.org/cgi/content/short/420596v1?rss=1"
Denega, I.D'Enfert, C.Bachellier-Bassi, S.2018-09-20doi:10.1101/420596Cold Spring Harbor Laboratory Press2018-09-20
<![CDATA[
Condensin II inactivation in interphase does not affect chromatin folding or gene expression
]]>
https://biorxiv.org/cgi/content/short/437459v1?rss=1"
Abdennur, N.Schwarzer, W.Pekowska, A.Shaltiel, I. A.Huber, W.Haering, C. H.Mirny, L.Spitz, F.2018-10-07doi:10.1101/437459Cold Spring Harbor Laboratory Press2018-10-07
<![CDATA[
Competition for space induces cell elimination through compaction-driven ERK downregulation
]]>
https://biorxiv.org/cgi/content/short/447888v1?rss=1"
Moreno, E.Valon, L.Levillayer, F.Levayer, R.2018-10-27doi:10.1101/447888Cold Spring Harbor Laboratory Press2018-10-27
<![CDATA[
Sex differences in IL-17 determine chronicity in male versus female urinary tract infection
]]>
https://biorxiv.org/cgi/content/short/449124v1?rss=1"
Zychlinsky Scharff, A.Rousseau, M.Lacerda Mariano, L.Canton, T.Albert, M.Fontes, M.Duffy, D.Ingersoll, M. A.2018-10-22doi:10.1101/449124Cold Spring Harbor Laboratory Press2018-10-22
<![CDATA[
Diversification of giant and large eukaryotic dsDNA viruses predated the origin of modern eukaryotes
]]>
https://biorxiv.org/cgi/content/short/455816v1?rss=1"
Guglielmini, J.Woo, A.Krupovic, M.Forterre, P.Gaia, M.2018-10-29doi:10.1101/455816Cold Spring Harbor Laboratory Press2018-10-29
<![CDATA[
Spatio-temporal dynamics of dengue in Brazil: seasonal travelling waves and determinants of regional synchrony
]]>
https://biorxiv.org/cgi/content/short/475335v1?rss=1"
Churakov, M.Villabona-Arenas, C. J.Kraemer, M. U. G.Salje, H.Cauchemez, S.2018-11-20doi:10.1101/475335Cold Spring Harbor Laboratory Press2018-11-20
<![CDATA[
Differential cell fates of muscle stem cells are accompanied by symmetric segregation of canonical H3 histones in vivo
]]>
https://biorxiv.org/cgi/content/short/499913v1?rss=1"
Evano, B.Le Carrou, G.Almouzni, G.Tajbakhsh, S.2018-12-18doi:10.1101/499913Cold Spring Harbor Laboratory Press2018-12-18
<![CDATA[
RAISS: Robust and Accurate imputation from Summary Statistics
]]>
https://biorxiv.org/cgi/content/short/502880v1?rss=1"
Julienne, H.Shi, H.Pasaniuc, B.Aschard, H.2018-12-21doi:10.1101/502880Cold Spring Harbor Laboratory Press2018-12-21
<![CDATA[
A role for gut microbiota in m6A epitranscriptomic mRNA modifications in different host tissues
]]>
https://biorxiv.org/cgi/content/short/504266v1?rss=1"
Jabs, S.Becavin, C.Nahori, M.-A.Guerinau, V.Touboul, D.Ghozlane, A.Dillies, M.-A.Cossart, P.2018-12-21doi:10.1101/504266Cold Spring Harbor Laboratory Press2018-12-21
<![CDATA[
NK cells acquire epigenetic memory of LPS-induced systemic inflammation
]]>
https://biorxiv.org/cgi/content/short/506014v1?rss=1"
Rasid, O.Chevalier, C.Camarasa, T.Fitting, C.Cavaillon, J.-M.Hamon, M. A.2018-12-25doi:10.1101/506014Cold Spring Harbor Laboratory Press2018-12-25
<![CDATA[
Carriage of a single strain of non-toxigenic Corynebacterium diphtheriae biovar Belfanti (Corynebacterium belfantii) in four patients with cystic fibrosis
]]>
https://biorxiv.org/cgi/content/short/516880v1?rss=1"
Pivot, D.Fanton, A.Badell-Ocando, E.Benouachkou, M.Astruc, K.Huet, F.Amoureux, L.Neuwirth, C.Criscuolo, A.Aho, S.Toubiana, J.Brisse, S.2019-01-17doi:10.1101/516880Cold Spring Harbor Laboratory Press2019-01-17
<![CDATA[
Positively twisted: The complex evolutionary history of Reverse Gyrase suggests a non-hyperthermophilic Last Universal Common Ancestor
]]>
https://biorxiv.org/cgi/content/short/524215v1?rss=1"
Catchpole, R.Forterre, P.2019-01-20doi:10.1101/524215Cold Spring Harbor Laboratory Press2019-01-20
<![CDATA[
Towards an ″assayome″ for binary interactome mapping
]]>
https://biorxiv.org/cgi/content/short/530790v1?rss=1"
Choi, S. G.Olivet, J.Cassonnet, P.Vidalain, P.-O.Luck, K.Lambourne, L.Spirohn, K.Lemmens, I.Dos Santos, M.Demeret, C.Jones, L.Rangarajan, S.Bian, W.Coutant, E. P.Janin, Y. L.van der Werf, S.De Las Rivas, J.Tavernier, J.Twizere, J.-C.Hao, T.Hill, D. E.Vidal, M.Calderwood, M. A.Jacob, Y.2019-01-26doi:10.1101/530790Cold Spring Harbor Laboratory Press2019-01-26
<![CDATA[
An RNA-binding protein secreted by Listeria monocytogenes activates RIG-I signaling
]]>
https://biorxiv.org/cgi/content/short/543652v1?rss=1"
Pagliuso, A.Tham, T. N.Allemand, E.Robertin, S.Dupuy, B.Bertrand, Q.Becavin, C.Koutero, M.Najburg, V.Nahori, M.-A.Stavru, F.Dessen, A.Muchard, C.Lebreton, A.Komarova, A. V.Cossart, P.2019-02-07doi:10.1101/543652Cold Spring Harbor Laboratory Press2019-02-07
<![CDATA[
Genetic dissection of Rift Valley fever pathogenesis: Rfvs2 on mouse chromosome 11 enables survival to acute-onset hepatitis
]]>
https://biorxiv.org/cgi/content/short/545129v1?rss=1"
Batista, L.Jouvion, G.Simon-Chazottes, D.Houzelstein, D.Burlen-Defranoux, O.Boissiere, M.Tokuda, S.Zaverucha do Valle, T.Cumano, A.Flamand, M.Montagutelli, X.Panthier, J.-J.2019-02-08doi:10.1101/545129Cold Spring Harbor Laboratory Press2019-02-08
<![CDATA[
Genome-wide Interaction Studies by the CHARGE Gene-Lifestyle Interactions Working Group: what we have learned and what is coming next.
]]>
https://biorxiv.org/cgi/content/short/562157v1?rss=1"
Laville, V.Majarian, T.Sung, Y. J.Feitosa, M. F.Chasman, D.Bentley, A. R.Rotimi, C. N.Cupples, A. L.de Vries, P. S.Brown, M. R.Morrison, A. C.Kraja, A. T.Province, M.Schwander, K.Gauderman, J.Rao, D.Manning, A.Aschard, H.2019-02-28doi:10.1101/562157Cold Spring Harbor Laboratory Press2019-02-28
<![CDATA[
Midgut barriers prevent the replication and dissemination of the yellow fever vaccine in Aedes aegypti
]]>
https://biorxiv.org/cgi/content/short/577213v1?rss=1"
Danet, L.Beauclair, G.Berthet, M.Moratorio, G.Gracias, S.Tangy, F.Choumet, V.jouvenet, n.2019-03-13doi:10.1101/577213Cold Spring Harbor Laboratory Press2019-03-13
<![CDATA[
Immune profiling in M. tuberculosis infection enables stratification of patients with active disease
]]>
https://biorxiv.org/cgi/content/short/581298v1?rss=1"
Duffy, D.Nemes, E.Llibre, A.Rouilly, V.Filander, E.Africa, H.Mabwe, S.Jaxa, L.Charbit, B.Musvosvi, M.Mulenga, H.The Milieu Interieur Consortium,Thomas, S.Hatherill, M.Bilek, N.Scriba, T. J.Albert, M. L.2019-03-18doi:10.1101/581298Cold Spring Harbor Laboratory Press2019-03-18
<![CDATA[
A major role for Eco1 in regulating cohesin-mediated mitotic chromosome folding
]]>
https://biorxiv.org/cgi/content/short/589101v1?rss=1"
Dauban, L.Montagne, R.Thierry, A.Lazar-Stefanita, L.Gadal, O.Cournac, A.Koszul, R.Beckouet, F.2019-03-26doi:10.1101/589101Cold Spring Harbor Laboratory Press2019-03-26
<![CDATA[
Co-occurrence of multiple CRISPRs and cas clusters suggests epistatic interactions
]]>
https://biorxiv.org/cgi/content/short/592600v1?rss=1"
Bernheim, A.Bikard, D.Touchon, m.Rocha, E.2019-03-30doi:10.1101/592600Cold Spring Harbor Laboratory Press2019-03-30
<![CDATA[
The speciation and hybridization history of the genus Salmonella
]]>
https://biorxiv.org/cgi/content/short/598235v1?rss=1"
Criscuolo, A.Issenhuth-Jeanjean, S.Didelot, X.Thorell, K.Hale, J.Parkhill, J.Thomson, N.Weill, F.-X.Falush, D.Brisse, S.2019-04-05doi:10.1101/598235Cold Spring Harbor Laboratory Press2019-04-05
<![CDATA[
Optimization and validation of a quadruplex real-time PCR assay for the diagnosis of diphtheria
]]>
https://biorxiv.org/cgi/content/short/600270v1?rss=1"
Badell, E.Guillot, S.Tulliez, M.Pascal, M.Panunzi, L. G.Rose, S.Litt, D.Fry, N. K.Brisse, S.2019-04-06doi:10.1101/600270Cold Spring Harbor Laboratory Press2019-04-06
<![CDATA[
A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle
]]>
https://biorxiv.org/cgi/content/short/600841v1?rss=1"
Comai, G.Heude, E.Mella, S.Paisant, S.Pala, F.Gallardo, M.Kardon, G.Gopalakrishnan, S.Tajbakhsh, S.2019-04-05doi:10.1101/600841Cold Spring Harbor Laboratory Press2019-04-05
<![CDATA[
Crippling the bacterial cell wall molecular machinery
]]>
https://biorxiv.org/cgi/content/short/607697v1?rss=1"
Williams, A. H.Boneca, I.Wheeler, R.Deghmane, A.-E.Santecchia, I.Impens, F.Bastos, P. A. D.Hicham, S.Moya Nilges, M.Malosse, C.Chamot-Rooke, J.Haouz, A.Robins, W. P.Taha, M.-K.2019-04-12doi:10.1101/607697Cold Spring Harbor Laboratory Press2019-04-12
<![CDATA[
Mapping of multiple complementary sex determination loci in a parasitoid wasp
]]>
https://biorxiv.org/cgi/content/short/620229v1?rss=1"
Matthey-Doret, C.van der Kooi, C. J.Jeffries, D. L.Bast, J.Dennis, A. B.Vorburger, C.Schwander, T.2019-04-26doi:10.1101/620229Cold Spring Harbor Laboratory Press2019-04-26
<![CDATA[
AP-1 Imprints a Reversible Transcriptional Program of Senescent Cells
]]>
https://biorxiv.org/cgi/content/short/633594v1?rss=1"
Martinez Zamudio, R. I.Roux, P.-F.Freitas, J. A.Robinson, L.Dore, G.Sun, B.Gil, J.Herbig, U.Bischof, O.2019-05-09doi:10.1101/633594Cold Spring Harbor Laboratory Press2019-05-09
<![CDATA[
Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis
]]>
https://biorxiv.org/cgi/content/short/634501v1?rss=1"
Maffei, B.Laverriere, M.Wu, Y.Triboulet, S.Perrinet, S.Duchateau, M.Matondo, M.Hollis, R. L.Gourley, C.Rupp, J.Keillor, J. W.Subtil, A.2019-05-10doi:10.1101/634501Cold Spring Harbor Laboratory Press2019-05-10
<![CDATA[
Leishmania targets the macrophage epigenome and dampens the NF-κB/NLRP3- mediated inflammatory response
]]>
https://biorxiv.org/cgi/content/short/649632v1?rss=1"
Lecoeur, H.Prina, E.Rosazza, T.Kokou, K.N'Diaye, P.Aulner, N.Bussotti, G.Varet, H.Weil, R.Xing, Y.Meng, G. X.Spaeth, G. F.2019-05-24doi:10.1101/649632Cold Spring Harbor Laboratory Press2019-05-24
<![CDATA[
The Human Dynamic Clamp reveals the fronto-parietal network linking real-time social coordination and cognition
]]>
https://biorxiv.org/cgi/content/short/651232v1?rss=1"
Dumas, G.Moreau, Q.Tognoli, E.Kelso, J. A. S.2019-05-27doi:10.1101/651232Cold Spring Harbor Laboratory Press2019-05-27
<![CDATA[
Systematic detection of divergent brain proteins in human evolution and their roles in cognition
]]>
https://biorxiv.org/cgi/content/short/658658v1?rss=1"
Dumas, G.Malesys, S.Bourgeron, T.2019-06-03doi:10.1101/658658Cold Spring Harbor Laboratory Press2019-06-03
<![CDATA[
The impact of rainfall on drinking water quality in Antananarivo, Madagascar
]]>
https://biorxiv.org/cgi/content/short/666826v1?rss=1"
Bastaraud, A.Perthame, E.RAKOTONDRAMANGA, J.-M.MAHAZOSAOTRA, J.RAVAONINDRINA, N.Jambou, R.2019-06-10doi:10.1101/666826Cold Spring Harbor Laboratory Press2019-06-10
<![CDATA[
Genetic diversity of Collaborative Cross mice controls viral replication, clinical severity and brain pathology induced by Zika virus infection, independently of Oas1b
]]>
https://biorxiv.org/cgi/content/short/677484v1?rss=1"
Manet, C.Simon-Loriere, E.Jouvion, G.Hardy, D.Prot, M.Flamand, M.Panthier, J.-J.Sakuntabhai, A.Montagutelli, X.2019-06-21doi:10.1101/677484Cold Spring Harbor Laboratory Press2019-06-21
<![CDATA[
Specific targeting of intestinal Prevotella copri by a Listeria monocytogenes bacteriocin
]]>
https://biorxiv.org/cgi/content/short/680801v1?rss=1"
Rolhion, N.Chassaing, B.Nahori, M.-A.de Bodt, J.Moura, A.Lecuit, M.Dussurget, O.Berard, M.Marzorati, M.Fehlner-Peach, H.Littman, D. R.Gewirtz, A. T.Van de Wiele, T.Cossart, P.2019-07-02doi:10.1101/680801Cold Spring Harbor Laboratory Press2019-07-02
<![CDATA[
Excess calorie intake early in life increases susceptibility to colitis in the adult
]]>
https://biorxiv.org/cgi/content/short/681759v1?rss=1"
Alnabhani, Z.Dulauroy, S.Lecuyer, E.Polomack, B.Berard, M.Eberl, G.2019-06-26doi:10.1101/681759Cold Spring Harbor Laboratory Press2019-06-26
<![CDATA[
Heterogeneous expression of Pil3 pilus is critical for Streptococcus gallolyticus translocation across polarized colonic epithelial monolayers
]]>
https://biorxiv.org/cgi/content/short/682278v1?rss=1"
Dramsi, S.Martins, M.du Merle, L.Trieu-Cuot, P.2019-06-25doi:10.1101/682278Cold Spring Harbor Laboratory Press2019-06-25
<![CDATA[
Deriving stratified effects from joint models investigating Gene-Environment Interactions
]]>
https://biorxiv.org/cgi/content/short/693218v1?rss=1"
Laville, V.Majarian, T.de Vries, P. S.Bentley, A. R.Feitosa, M. F.Sung, Y. J.Rao, D.Manning, A.Aschard, H.CHARGE Gene-Lifestyle Interaction Working Group,2019-07-04doi:10.1101/693218Cold Spring Harbor Laboratory Press2019-07-04
<![CDATA[
Interferon-stimulated genes in zebrafish and human define an ancient arsenal of antiviral immunity
]]>
https://biorxiv.org/cgi/content/short/693333v1?rss=1"
Levraud, J.-P.Jouneau, L.Briolat, V.Laghi, V.Boudinot, P.2019-07-04doi:10.1101/693333Cold Spring Harbor Laboratory Press2019-07-04
<![CDATA[
Description of Klebsiella spallanzanii sp. nov. and of Klebsiella pasteurii sp. nov.
]]>
https://biorxiv.org/cgi/content/short/703363v1?rss=1"
Merla, C.Rodrigues, C.Passet, V.Corbella, M.Thorpe, H. A.Kallonen, T. V. S.Zong, Z.Marone, P.Bandi, C.Sassera, D.Corander, J.Feil, E. J.Brisse, S.2019-07-16doi:10.1101/703363Cold Spring Harbor Laboratory Press2019-07-16
<![CDATA[
Innate immune recognition of a bacterial MAMP leads to conditional activation of pro- or anti-inflammatory responses
]]>
https://biorxiv.org/cgi/content/short/717256v1?rss=1"
Park, J. H.Cornick, S.Nigro, G.Bertin, G.Dejardin, F.Smits, R.Berard, M.Langa Vives, F.Gomperts Boneca, I.Gewirtz, A.Chassaing, B.Barnich, N.Sansonetti, P.Eberl, G.2019-07-28doi:10.1101/717256Cold Spring Harbor Laboratory Press2019-07-28
<![CDATA[
The impact of gut microbiota on depressive-like behaviors and adult hippocampal neurogenesis requires the endocannabinoid system
]]>
https://biorxiv.org/cgi/content/short/718288v1?rss=1"
Chevalier, G.Siopi, E.Guenin-Mace, L.Pascal, M.Laval, T.Rifflet, A.Gomperts Boneca, I.Demangel, C.Leulier, F.Lepousez, G.Eberl, G.Lledo, P.-M.2019-07-29doi:10.1101/718288Cold Spring Harbor Laboratory Press2019-07-29
<![CDATA[
A loss-of-function mutation in Itgal contributes to the high susceptibility of Collaborative Cross strain CC042 to Salmonella infections
]]>
https://biorxiv.org/cgi/content/short/723478v1?rss=1"
Zhang, J.Teh, M.Kim, J.Eva, M. M.Cayrol, R.Meade, R. K.Nijnik, A.Montagutelli, X.Malo, D.Jaubert, J.2019-08-02doi:10.1101/723478Cold Spring Harbor Laboratory Press2019-08-02
<![CDATA[
Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly
]]>
https://biorxiv.org/cgi/content/short/728964v1?rss=1"
Lemos, M.Mallet, A.Bertiaux, E.Imbert, A.Rotureau, B.Bastin, P.2019-08-08doi:10.1101/728964Cold Spring Harbor Laboratory Press2019-08-08
<![CDATA[
Essential dynamic interdependence of FtsZ and SepF for Z-ring and septum formation in Corynebacterium glutamicum
]]>
https://biorxiv.org/cgi/content/short/732925v1?rss=1"
Sogues, A.Martinez, M.Gaday, Q.Ben Assaya, M.Grana, M.Voegele, A.VanNieuwenhze, M.England, P.Haouz, A.Chenal, A.Trepout, S.Duran, R.Wehenkel, A. M.Alzari, P. M.2019-08-13doi:10.1101/732925Cold Spring Harbor Laboratory Press2019-08-13
<![CDATA[
Evolution of the PRD1-adenovirus lineage: a viral tree of life incongruent with the cellular universal tree of life
]]>
https://biorxiv.org/cgi/content/short/741942v1?rss=1"
Woo, A. C.Gaia, M.Guglielmini, J.Da Cunha, V.Forterre, P.2019-08-21doi:10.1101/741942Cold Spring Harbor Laboratory Press2019-08-21
<![CDATA[
Increased contrast of the grey-white matter boundary in the motor, visual and auditory areas in Autism Spectrum Disorders
]]>
https://biorxiv.org/cgi/content/short/750117v1?rss=1"
Fouquet, M.Traut, N.Beggiato, A.Delorme, R.Bourgeron, T.Toro, R.2019-09-05doi:10.1101/750117Cold Spring Harbor Laboratory Press2019-09-05
<![CDATA[
Tudor-SN promotes early replication of dengue virus in the Aedes aegypti midgut
]]>
https://biorxiv.org/cgi/content/short/751362v1?rss=1"
Merkling, S. H.Raquin, V.Dabo, S.Moltini-Conclois, I.Frangeul, L.Varet, H.Saleh, M. C.LAMBRECHTS, L.2019-08-31doi:10.1101/751362Cold Spring Harbor Laboratory Press2019-08-31
<![CDATA[
The antibiotic bedaquiline activates host macrophage innate immune resistance to bacterial infection
]]>
https://biorxiv.org/cgi/content/short/758318v1?rss=1"
Giraud-Gatineau, A.Coya, J. M.Maure, A.Biton, A.Thomson, M.Bernard, E. M.Gutierrez, M. G.Larrouy-Maumus, G.Brosch, R.Gicquel, B.Tailleux, L.2019-09-06doi:10.1101/758318Cold Spring Harbor Laboratory Press2019-09-06
<![CDATA[
Cell-wall synthases contribute to bacterial cell-envelope integrity by actively repairing defects
]]>
https://biorxiv.org/cgi/content/short/763508v1?rss=1"
Vigouroux, A.Cordier, B.Aristov, A.Oldewurtel, E. R.Özbaykal, G.Chaze, T.Matondo, M.Bikard, D.van Teeffelen, S.2019-09-12doi:10.1101/763508Cold Spring Harbor Laboratory Press2019-09-12
<![CDATA[
A new high-throughput tool to screen mosquito-borne viruses in Zika virus endemic/epidemic areas
]]>
https://biorxiv.org/cgi/content/short/764704v1?rss=1"
Moutailler, S.Yousfi, L.Mousson, L.Devillers, E.Vazeille, M.Vega Rua, A.Perrin, Y.Jourdain, F.Chandre, F.Cannet, A.Chantilly, S.Restrepo, J.Guidez, A.Dusfour, I.Vieira Santos de Abreu, F.Pereira dos Santos, T.Jiolle, D.Visser, T. M.Koenraadt, C. J. M.Wongsokarijo, M.Diallo, M.Diallo, D.Gaye, A.Boyer, S.Duong, V.Piorkowski, G.Paupy, C.Lourenco-de-Oliveira, R.de Lamballerie, X.Failloux, A.-B.2019-09-11doi:10.1101/764704Cold Spring Harbor Laboratory Press2019-09-11
<![CDATA[
Resection and repair of a Cas9 double-strand break at CTG trinucleotide repeats induces local and extensive chromosomal rearrangements
]]>
https://biorxiv.org/cgi/content/short/782268v1?rss=1"
Mosbach, V.Viterbo, D.Descorps-Declere, S.Poggi, L.Vaysse-Zinkhofer, W.Richard, G.-F.2019-09-25doi:10.1101/782268Cold Spring Harbor Laboratory Press2019-09-25
<![CDATA[
The APL1 immune factor is encoded by a single ancestral gene in most Anopheles species and expanded to three paralogs with distinct function in the Anopheles gambiae complex
]]>
https://biorxiv.org/cgi/content/short/785089v1?rss=1"
Mitri, C.Bischoff, E.Eiglmeier, K.Holm, I.Dieme, C.Brito-Fravallo, E.Raz, A.Zakeri, S.Nejad, M. I. K.Djadid, N. D.Vernick, K. D.Riehle, M. M.2019-09-27doi:10.1101/785089Cold Spring Harbor Laboratory Press2019-09-27
<![CDATA[
Differential contribution of Anopheles coustani and Anopheles arabiensis to the transmission of Plasmodium falciparum and Plasmodium vivax in two neighboring villages of Madagascar
]]>
https://biorxiv.org/cgi/content/short/787432v1?rss=1"
Goupeyou-Youmsi, J. M.Rakotondranaivo, T.Puchot, N.Peterson, I.GIROD, R.Vigan-Womas, I.Ndiath, M. O.Bourgouin, C.2019-09-30doi:10.1101/787432Cold Spring Harbor Laboratory Press2019-09-30
<![CDATA[
A wave of hematopoietic stem cell-derived T/ILC-restricted progenitors initiates thymopoiesis and shapes the embryonic thymus architecture.
]]>
https://biorxiv.org/cgi/content/short/791103v1?rss=1"
Elsaid, R.Meunier, S.Defranoux, O.Soraes-da-Silva, F.Perchet, T.Iturri, L.Freyer, L.Vieira, P.Pereira, P.Golub, R.Bandeira, A.Gomez Perdiguero, E.Cumano, A.2019-10-02doi:10.1101/791103Cold Spring Harbor Laboratory Press2019-10-02
<![CDATA[
Legionella pneumophila infection and antibiotic treatment engenders a highly disturbed pulmonary microbiome with decreased microbial diversity
]]>
https://biorxiv.org/cgi/content/short/808238v1?rss=1"
Perez-Cobas, A. E.Ginevra, C.Rusniok, C.Jarraud, S.Buchrieser, C.2019-10-17doi:10.1101/808238Cold Spring Harbor Laboratory Press2019-10-17
<![CDATA[
Bread feeding is a robust and more physiological enteropathogen administration method compared to oral gavage
]]>
https://biorxiv.org/cgi/content/short/808832v1?rss=1"
Derbise, A.Echenique-Rivera, H.Garcia-Lopez, M.Beau, R.Mattei, M.Dersch, P.Pizarro-Cerda, J.2019-10-17doi:10.1101/808832Cold Spring Harbor Laboratory Press2019-10-17
<![CDATA[
The spatial heterogeneity of the gut limits bacteriophage predation leading to the coexistence of antagonist populations of bacteria and their viruses
]]>
https://biorxiv.org/cgi/content/short/810705v1?rss=1"
Lourenco, M.Chaffringeon, L.Lamy-Besnier, Q.Campagne, P.Eberl, C.Berard, M.Stecher, B.Debarbieux, L.De Sordi, L.2019-10-21doi:10.1101/810705Cold Spring Harbor Laboratory Press2019-10-21
<![CDATA[
Polarly localized EccE1is required for ESX-1 function and stabilization of ESX-1 membrane proteins in Mycobacterium tuberculosis
]]>
https://biorxiv.org/cgi/content/short/820324v1?rss=1"
Soler-Arnedo, P.Sala, C.Zhang, M.Cole, S. T.Piton, J.2019-10-30doi:10.1101/820324Cold Spring Harbor Laboratory Press2019-10-30
<![CDATA[
Subcutaneous vaccination with a live attenuated Yersinia pseudotuberculosis plague vaccine
]]>
https://biorxiv.org/cgi/content/short/822221v1?rss=1"
Derbise, A.Guillas, C.Gerke, C.Carniel, E.Pizarro Cerda, J.Demeure, C. E.2019-10-30doi:10.1101/822221Cold Spring Harbor Laboratory Press2019-10-30
<![CDATA[
Two common disease-associated TYK2 variants impact exon splicing and TYK2 dosage
]]>
https://biorxiv.org/cgi/content/short/830232v1?rss=1"
T, Val362Phe). We found that this amino acid substitution does not alter TYK2 expression, catalytic activity or ability to relay signaling in EBV-B cell lines or in reconstituted TYK2-null cells. Based on in silico predictions that these variants may impact splicing of exon 8, we: i) analyzed TYK2 transcripts in genotyped EBV-B cells and in CRISPR/Cas9-edited cells, ii) measured splicing using minigene assays, and iii) performed eQTL (expression quantitative trait locus) analysis of TYK2 transcripts in primary monocytes and whole blood cells. Our results reveal that the two variants promote the inclusion of exon 8, which, we demonstrate, is essential for TYK2 binding to cognate receptors. In addition and in line with GTEx (Genetic Tissue Expression) data, our eQTL results show that rs2304256 mildly enhances TYK2 expression in whole blood. In all, these findings suggest that these TYK2 variants are not neutral but instead have a potential impact in AID.
]]>Li, Z.Rotival, M.Patin, E.Michel, F.Pellegrini, S.2019-11-04doi:10.1101/830232Cold Spring Harbor Laboratory Press2019-11-04
<![CDATA[
Description of Corynebacterium rouxii sp. nov., a novel member of the diphtheriae species complex
]]>
https://biorxiv.org/cgi/content/short/855692v1?rss=1"
Badell, E.Hennart, M.Rodrigues, C.Passet, V.Dazas, M.Panunzi, L.Bouchez, V.Carmi-Leroy, A.Toubiana, J.Brisse, S.2019-11-26doi:10.1101/855692Cold Spring Harbor Laboratory Press2019-11-26
<![CDATA[
Differential efficacies of Cas nucleases on microsatellites involved in human disorders and associated off-target mutations
]]>
https://biorxiv.org/cgi/content/short/857714v1?rss=1"
Poggi, L.Emmenegger, L.Descorps-Declere, S.Dumas, B.Richard, G.-F.2019-11-29doi:10.1101/857714Cold Spring Harbor Laboratory Press2019-11-29
<![CDATA[
Primary mammary organoid model of lactation and involution
]]>
https://biorxiv.org/cgi/content/short/859645v1?rss=1"
Sumbal, J.Chiche, A.Charifou, E.Koledova, Z.LI, H.2019-11-29doi:10.1101/859645Cold Spring Harbor Laboratory Press2019-11-29
<![CDATA[
The hippocampus as a perceptual map: neuronal and behavioral discrimination during memory encoding
]]>
https://biorxiv.org/cgi/content/short/868794v1?rss=1"
Allegra, M.Posani, L.Schmidt-Hieber, C.2019-12-08doi:10.1101/868794Cold Spring Harbor Laboratory Press2019-12-08
<![CDATA[
Identification and analysis of integrons and cassette arrays in bacterial genomes
]]>
https://biorxiv.org/cgi/content/short/030866v1?rss=1"
Jean CuryThomas JovéMarie TouchonBertrand NéronEduardo P. C. Rocha2015-11-09doi:10.1101/030866Cold Spring Harbor Laboratory Press2015-11-09
<![CDATA[
Actin activates Pseudomonas aeruginosa ExoY nucleotidyl cyclase toxin and ExoY-like effector domains from MARTX toxins
]]>
https://biorxiv.org/cgi/content/short/032201v1?rss=1"
10,000 fold) ExoY activity. ExoY co-localizes in vivo with actin filaments in transfected cells and, in vitro, it interferes with the regulation of actin assembly/disassembly-dynamics mediated by important F-actin-binding proteins. We further show that actin also activates an ExoY-like adenylate cyclase from a Vibrio species. Our results thus highlight a new sub-class within the class II adenylyl cyclase family, defined as actin-activated nucleotidyl cyclase (AA-NC) toxins.
]]>Dorothee Raoux-BarbotCosmin SaveanuAbdelkader NamaneVasily OgryzkoLina WorpenbergSouad FellousElodie AssayagDaniel LadantLouis RenaultUndine Mechold2015-11-18doi:10.1101/032201Cold Spring Harbor Laboratory Press2015-11-18
<![CDATA[
Meta3C analysis of a mouse gut microbiome
]]>
https://biorxiv.org/cgi/content/short/034793v1?rss=1"
Martial MarboutyLyam BaudryAxel CournacRomain Koszul2015-12-17doi:10.1101/034793Cold Spring Harbor Laboratory Press2015-12-17
<![CDATA[
Quiescence unveils a novel mutational force in fission yeast
]]>
https://biorxiv.org/cgi/content/short/126755v1?rss=1"
Gangloff, S.Achaz, G.Villain, A.Miled, S.Denis, C.Arcangioli, B.2017-04-11doi:10.1101/126755Cold Spring Harbor Laboratory Press2017-04-11
<![CDATA[
Boosting Felsenstein Phylogenetic Bootstrap
]]>
https://biorxiv.org/cgi/content/short/154542v1?rss=1"
Lemoine, F.Domelevo Entfellner, J.-B.Wilkinson, E.De Oliveira, T.Gascuel, O.2017-06-23doi:10.1101/154542Cold Spring Harbor Laboratory Press2017-06-23
<![CDATA[
Model-based analysis of experimental hut data elucidates multifaceted effects of a volatile chemical on Aedes aegypti mosquitoes
]]>
https://biorxiv.org/cgi/content/short/164293v1?rss=1"
ten Bosch, Q. A.Castro-Llanos, F.Manda, H.Morrison, A. C.Grieco, J. P.Achee, N. L.Perkins, A.2017-07-17doi:10.1101/164293Cold Spring Harbor Laboratory Press2017-07-17
<![CDATA[
Antisense transcriptional interference mediates condition-specific gene repression in budding yeast
]]>
https://biorxiv.org/cgi/content/short/169730v1?rss=1"
Nevers, A.Doyen, A.Malabat, C.Neron, B.Kergrohen, T.Jacquier, A.Badis, G.2017-07-28doi:10.1101/169730Cold Spring Harbor Laboratory Press2017-07-28
<![CDATA[
Diverse laboratory colonies of Aedes aegypti harbor the same adult midgut bacterial microbiome
]]>
https://biorxiv.org/cgi/content/short/200659v1?rss=1"
Dickson, L. B.Ghozlane, A.Volant, S.Bouchier, C.Ma, L.Vega-Rua, A.Dusfour, I.Jiolle, D.Paupy, C.Mayanja, M. N.Kohl, A.Lutwama, J. J.Duong, V.Lambrechts, L.2017-10-10doi:10.1101/200659Cold Spring Harbor Laboratory Press2017-10-10
<![CDATA[
Modular prophage interactions driven by capsule serotype select for capsule loss under phage predation
]]>
https://biorxiv.org/cgi/content/short/2019.12.17.878363v1?rss=1"
Moura de Sousa, J. A.Buffet, A.Haudiquet, M.Rocha, E. P. C.Rendueles, O.2019-12-17doi:10.1101/2019.12.17.878363Cold Spring Harbor Laboratory Press2019-12-17
<![CDATA[
Chromosome-level quality scaffolding of brown algal genomes using InstaGRAAL, a proximity ligation-based scaffolder
]]>
https://biorxiv.org/cgi/content/short/2019.12.22.882084v1?rss=1"
Baudry, L.Marbouty, M.Marie-Nelly, H.Cormier, A.Guiglielmoni, N.Avia, K.Loe Mie, Y.Godfroy, O.Sterck, L.Cock, M.Zimmer, C.Coehlo, S. M.Koszul, R.2019-12-23doi:10.1101/2019.12.22.882084Cold Spring Harbor Laboratory Press2019-12-23
<![CDATA[
Bacteria contribute to mosquito development via folate biosynthesis and energy storage
]]>
https://biorxiv.org/cgi/content/short/2019.12.31.891671v1?rss=1"
Romoli, O.Schonbeck, J. C.Hapfelmeier, S.Gendrin, M.2019-12-31doi:10.1101/2019.12.31.891671Cold Spring Harbor Laboratory Press2019-12-31
<![CDATA[
The Flemmingsome reveals an ESCRT-to-membrane coupling required for completion of cytokinesis
]]>
https://biorxiv.org/cgi/content/short/2020.01.15.907857v1?rss=1"
Addi, C.Presle, A.Fremont, S.Cuvelier, F.Rocancourt, M.Milin, F.Schmutz, S.Chamot-Rooke, J.Douche, T.Duchateau, M.Giai Gianetto, Q.Menager, H.Matondo, M.Zimmermann, P.Gupta-Rossi, N.Echard, A.2020-01-15doi:10.1101/2020.01.15.907857Cold Spring Harbor Laboratory Press2020-01-15
<![CDATA[
Bacterial FtsZ induces mitochondrial fission in human cells
]]>
https://biorxiv.org/cgi/content/short/2020.01.24.917146v1?rss=1"
Spier, A.Sachse, M.Tham, N. T.Matondo, M.Cossart, P.Stavru, F.2020-01-24doi:10.1101/2020.01.24.917146Cold Spring Harbor Laboratory Press2020-01-24
<![CDATA[
Structural basis for the increased processivity of D-family DNA polymerases in complex with PCNA
]]>
https://biorxiv.org/cgi/content/short/2020.01.29.925263v1?rss=1"
Madru, C.Raia, P.Hugonneau-Beaufet, I.Pehau-Arnaudet, G.England, P.Lindahl, E.Delarue, M.Carroni, M.Sauguet, L.2020-01-30doi:10.1101/2020.01.29.925263Cold Spring Harbor Laboratory Press2020-01-30
<![CDATA[
Phylogenetic background and habitat drive the genetic diversification of Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/2020.02.12.945709v1?rss=1"
Touchon, M.Perrin, A.De Sousa, J. A. M.Vangchhia, B.burn, S.O'brien, C.Denamur, E.Gordon, D.Rocha, E. P.2020-02-13doi:10.1101/2020.02.12.945709Cold Spring Harbor Laboratory Press2020-02-13
<![CDATA[
An original model of brain infection identifies B Streptococcus lipoprotein Blr as a ligand exploiting host endocytosis for blood-brain barrier crossing.
]]>
https://biorxiv.org/cgi/content/short/2020.02.28.970376v1?rss=1"
Benmimoun, B.Papastefanaki, F.Perichon, B.Segklia, K.Roby, N.Miriagou, V.Matsas, R.Dramsi, S.Speder, P.2020-02-28doi:10.1101/2020.02.28.970376Cold Spring Harbor Laboratory Press2020-02-28
<![CDATA[
Chromosight: A computer vision program for pattern detection in chromosome contact maps
]]>
https://biorxiv.org/cgi/content/short/2020.03.08.981910v1?rss=1"
Matthey-Doret, C.Baudry, L.Breuer, A.Guiglielmoni, N.Moreau, P.Vigouroux, A.Montagne, R.Scolari, V.Politis, L.Meot, A.Oriol, E.Chanut, P.-H.Campeas, A.Jean, E.Koszul, R.Cournac, A.2020-03-08doi:10.1101/2020.03.08.981910Cold Spring Harbor Laboratory Press2020-03-08
<![CDATA[
A new form of actin assembly around the Shigella-containing vacuole regulates its intracellular niche
]]>
https://biorxiv.org/cgi/content/short/2020.03.12.988097v1?rss=1"
Kühn, S.Bergqvist, J.Barrio, L.Lebreton, S.Zurzolo, C.Enninga, J.2020-03-12doi:10.1101/2020.03.12.988097Cold Spring Harbor Laboratory Press2020-03-12
<![CDATA[
Robustness of epithelial sealing is an emerging property of local ERK feedbacks driven by cell elimination
]]>
https://biorxiv.org/cgi/content/short/2020.03.17.994921v1?rss=1"
Valon, L.Levillayer, F.Davidovic, A.Chouly, M.Cerqueira-Campos, F.Levayer, R.2020-03-18doi:10.1101/2020.03.17.994921Cold Spring Harbor Laboratory Press2020-03-18
<![CDATA[
Differential small RNA responses against co-infecting insect-specific viruses in Aedes albopictus mosquitoes
]]>
https://biorxiv.org/cgi/content/short/2020.03.28.012062v1?rss=1"
Frangeul, L.Blanc, H.Saleh, M.-C.Suzuki, Y.2020-03-29doi:10.1101/2020.03.28.012062Cold Spring Harbor Laboratory Press2020-03-29
<![CDATA[
Non-retroviral endogenous viral element limits cognate virus replication in Aedes aegypti ovaries
]]>
https://biorxiv.org/cgi/content/short/2020.03.28.013441v1?rss=1"
Suzuki, Y.Baidaliuk, A.Miesen, P.Frangeul, L.Crist, A. B.Merkling, S. H.Fontaine, A.Lequime, S.Moltini-Conclois, I.Blanc, H.van Rij, R. P.Lambrechts, L.Saleh, M.-C.2020-03-30doi:10.1101/2020.03.28.013441Cold Spring Harbor Laboratory Press2020-03-30
<![CDATA[
DIVA: natural navigation inside 3D images usingvirtual reality
]]>
https://biorxiv.org/cgi/content/short/2020.04.09.019935v1?rss=1"
El Beheiry, M.Godard, C.Caporal, C.Marcon, V.Ostertag, C.Sliti, O.Doutreligne, S.Fournier, S.Hajj, B.Dahan, M.Masson, J.-B.2020-04-10doi:10.1101/2020.04.09.019935Cold Spring Harbor Laboratory Press2020-04-10
<![CDATA[
Genome diversification via genetic exchanges between temperate and virulent bacteriophages
]]>
https://biorxiv.org/cgi/content/short/2020.04.14.041137v1?rss=1"
Sousa, J. M. d.Pfeifer, E.Touchon, M.Rocha, E. P. C.2020-04-14doi:10.1101/2020.04.14.041137Cold Spring Harbor Laboratory Press2020-04-14
<![CDATA[
Autotransporters drive biofilm formation and auto-aggregation in the diderm Firmicute Veillonella parvula
]]>
https://biorxiv.org/cgi/content/short/2020.04.15.042101v1?rss=1"
Bechon, N.Jimenez-Fernandez, A.Witwinowski, J.Bierque, E.Taib, N.Cokelaer, T.Ma, L.Ghigo, J.-M.Gribaldo, S.Beloin, C.2020-04-16doi:10.1101/2020.04.15.042101Cold Spring Harbor Laboratory Press2020-04-16
<![CDATA[
The cationic amino acid exporter Slc7a7 is vital for and induced in tissue macrophages with sustained efferocytic activity
]]>
https://biorxiv.org/cgi/content/short/2020.04.20.051664v1?rss=1"
Demy, D. L.Carrere, M.Noche, R.Tauzin, M.Le Bris, M.Baek, C.Yousfi, M.Leshchiner, I.Goessling, W.Herbomel, P.2020-04-21doi:10.1101/2020.04.20.051664Cold Spring Harbor Laboratory Press2020-04-21
<![CDATA[
Selection for the bacterial capsule in the absence of biotic and abiotic aggressions depends on growth conditions
]]>
https://biorxiv.org/cgi/content/short/2020.04.27.059774v1?rss=1"
Buffet, A.Rocha, E. P. C.Rendueles, O.2020-04-28doi:10.1101/2020.04.27.059774Cold Spring Harbor Laboratory Press2020-04-28
<![CDATA[
Central role and structure of the membrane pseudokinase YukC in the antibacterial Bacillus subtilis Type VIIb Secretion System.
]]>
https://biorxiv.org/cgi/content/short/2020.05.09.085852v1?rss=1"
Tassinari, M.Doan, T.Bellinzoni, M.Chabalier, M.Ben-Assaya, M.Martinez, M.Gaday, Q.Alzari, P. M.Cascales, E.Fronzes, R.GUBELLINI, F.2020-05-09doi:10.1101/2020.05.09.085852Cold Spring Harbor Laboratory Press2020-05-09
<![CDATA[
The RNase J-based RNA degradosome is compartmentalized in the gastric pathogen Helicobacter pylori
]]>
https://biorxiv.org/cgi/content/short/2020.05.11.085670v1?rss=1"
Tejada-Arranz, A.Galtier, E.El Mortaji, L.Turlin, E.Ershov, D.DE REUSE, H.2020-05-12doi:10.1101/2020.05.11.085670Cold Spring Harbor Laboratory Press2020-05-12
<![CDATA[
Phages - bacteria interactions network of the healthy human gut
]]>
https://biorxiv.org/cgi/content/short/2020.05.13.093716v1?rss=1"
Marbouty, M.Thierry, A.Koszul, R.2020-05-15doi:10.1101/2020.05.13.093716Cold Spring Harbor Laboratory Press2020-05-15
<![CDATA[
Intraflagellar transport during the assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies
]]>
https://biorxiv.org/cgi/content/short/2020.05.14.095216v1?rss=1"
Bertiaux, E.Mallet, A.Rotureau, B.Bastin, P.2020-05-15doi:10.1101/2020.05.14.095216Cold Spring Harbor Laboratory Press2020-05-15
<![CDATA[
The desensitization pathway of GABAA receptors, one subunit at a time
]]>
https://biorxiv.org/cgi/content/short/2020.05.18.101287v1?rss=1"
Gielen, M.Barilone, N.Corringer, P.-J.2020-05-19doi:10.1101/2020.05.18.101287Cold Spring Harbor Laboratory Press2020-05-19
<![CDATA[
The impact of genetic diversity on gene essentiality within the E. coli species
]]>
https://biorxiv.org/cgi/content/short/2020.05.25.114553v1?rss=1"
Rousset, F.Cabezas Caballero, J.Piastra-Facon, F.Fernandez-Rodriguez, J.Clermont, O.Denamur, E.Rocha, E. P. C.Bikard, D.2020-05-25doi:10.1101/2020.05.25.114553Cold Spring Harbor Laboratory Press2020-05-25
<![CDATA[
COVID-Align: Accurate online alignment of hCoV-19 genomes using a profile HMM
]]>
https://biorxiv.org/cgi/content/short/2020.05.25.114884v1?rss=1"
Lemoine, F.Blassel, L.Voznica, J.Gascuel, O.2020-05-25doi:10.1101/2020.05.25.114884Cold Spring Harbor Laboratory Press2020-05-25
<![CDATA[
Neuralized regulates a travelling wave of Epithelium-to-Neural Stem Cell morphogenesis in Drosophila
]]>
https://biorxiv.org/cgi/content/short/2020.06.02.129353v1?rss=1"
Shard, C.Luna Escalante, J.Schweisguth, F.2020-06-02doi:10.1101/2020.06.02.129353Cold Spring Harbor Laboratory Press2020-06-02
<![CDATA[
Unveiling the inter individual variability of human fibroblasts innate immune response using robust cell-based protocols
]]>
https://biorxiv.org/cgi/content/short/2020.06.04.133264v1?rss=1"
David-Watine, B.Chansard, A.Poujol de Molliens, M.Dubrulle, N.Falanga, P. B.Stephen, T.Hasan, M.van Zandbergen, G.Aulner, N.Shorte, S. L.Milieu interieur Consortium,2020-06-05doi:10.1101/2020.06.04.133264Cold Spring Harbor Laboratory Press2020-06-05
<![CDATA[
The combined action of Esrrb and Nr5a2 is essential for naive pluripotency.
]]>
https://biorxiv.org/cgi/content/short/2020.06.05.134999v1?rss=1"
Festuccia, N.Owens, N.Chervova, A.Dubois, A.Navarro, P.2020-06-06doi:10.1101/2020.06.05.134999Cold Spring Harbor Laboratory Press2020-06-06
<![CDATA[
Giant viruses encode novel types of actins possibly related to the origin of eukaryotic actin: the viractins
]]>
https://biorxiv.org/cgi/content/short/2020.06.16.150565v1?rss=1"
Da Cunha, V.Gaïa, M.Ogata, H.Jaillon, O.Delmont, T. O.Forterre, P.2020-06-16doi:10.1101/2020.06.16.150565Cold Spring Harbor Laboratory Press2020-06-16
<![CDATA[
Dynamic spatiotemporal coordination of neural stem cell fate decisions through local feedback in the adult vertebrate brain
]]>
https://biorxiv.org/cgi/content/short/2020.07.15.205021v1?rss=1"
Dray, N.Mancini, L.Binshtok, U.Cheysson, F.Supatto, W.Mahou, P.Bedu, S.Ortica, S.Krecsmarik, M.Herbert, S.Masson, J.-B.Tinevez, J.-Y.Lang, G.Beaurepaire, E.Sprinzak, D.Bally-Cuif, L.2020-07-16doi:10.1101/2020.07.15.205021Cold Spring Harbor Laboratory Press2020-07-16
<![CDATA[
Intranasal Immunization with a Lentiviral Vector Coding for SARS-CoV-2 Spike Protein Confers Vigorous Protection in Pre-Clinical Animal Models
]]>
https://biorxiv.org/cgi/content/short/2020.07.21.214049v1?rss=1"
3 log10 decrease in the lung viral loads and avoided local inflammation. Moreover, both integrative and non-integrative LV platforms displayed a strong vaccine efficacy and inhibited lung deleterious injury in golden hamsters, which are naturally permissive to SARS-CoV-2 replication and restitute the human COVID-19 physiopathology. Our results provide evidence of marked prophylactic effects of the LV-based vaccination against SARS-CoV-2 and designate the intranasal immunization as a powerful approach against COVID-19.
HighlightsA lentiviral vector encoding for Spike predicts a promising COVID-19 vaccine
Targeting the immune response to the upper respiratory tract is key to protection
Intranasal vaccination induces protective mucosal immunity against SARS-CoV-2
Lung anti-Spike IgA responses correlate with protection and reduced inflammation
]]>MAJLESSI, L.Ku, M.-W.Bourgine, M.Authie, P.Lopez, J.Nemirov, K.Moncoq, F.Noirat, A.Vesin, B.Nevo, F.Blanc, C.Souque, P.Simon, E.Tabbal, H.Mouquet, H.Anna, F.Martin, A.Escriou, N.Charneau, P.2020-07-21doi:10.1101/2020.07.21.214049Cold Spring Harbor Laboratory Press2020-07-21
<![CDATA[
Microtubules tune mechanosensitive cell responses
]]>
https://biorxiv.org/cgi/content/short/2020.07.22.205203v1?rss=1"
Seetharaman, S.Vianay, B.Roca, V.De Pascalis, C.Boëda, B.Dingli, F.Loew, D.Vassilopoulos, S.Thery, M.Etienne-Manneville, S.2020-07-23doi:10.1101/2020.07.22.205203Cold Spring Harbor Laboratory Press2020-07-23
<![CDATA[
Drivers of ESBL-producing Escherichia coli dynamics in calf fattening farms: a modelling study
]]>
https://biorxiv.org/cgi/content/short/2020.09.14.296186v1?rss=1"
Bastard, J.Haenni, M.Gay, E.Glaser, P.Madec, J.-Y.Temime, L.Opatowski, L.2020-09-14doi:10.1101/2020.09.14.296186Cold Spring Harbor Laboratory Press2020-09-14
<![CDATA[
High-throughput measurements of intra-cellular and secreted cytokine from single spheroids using anchored microfluidic droplets
]]>
https://biorxiv.org/cgi/content/short/2020.09.25.312900v1?rss=1"
Saint-Sardos, A.Sart, S.Lippera, K.Brient-Litzler, E.Michelin, S.Amselem, G.Baroud, C. N.2020-09-25doi:10.1101/2020.09.25.312900Cold Spring Harbor Laboratory Press2020-09-25
<![CDATA[
SepF is the FtsZ-anchor in Archaea: implications for cell division in the Last Universal Common Ancestor
]]>
https://biorxiv.org/cgi/content/short/2020.10.06.328377v1?rss=1"
Pende, N.Sogues, A.Megrian, D.Palabikyan, H.Sartori-Rupp, A.Graña, M.Rittmann, S. K.- M. R.Wehenkel, A. M.Alzari, P.Gribaldo, S.2020-10-06doi:10.1101/2020.10.06.328377Cold Spring Harbor Laboratory Press2020-10-06
<![CDATA[
COVID-19-associated olfactory dysfunction reveals SARS-CoV-2 neuroinvasion and persistence in the olfactory system
]]>
https://biorxiv.org/cgi/content/short/2020.11.18.388819v1?rss=1"
De Melo, G. D.Lazarini, F.Levallois, S.Hautefort, C.Michel, V.Larrous, F.Verillaud, B.Aparicio, C.Wagner, S.Gheusi, G.Kergoat, L.Kornobis, E.Cokelaer, T.Hervochon, R.Madec, Y.Roze, E.Salmon, D.Bourhy, H.Lecuit, M.Lledo, P.-M.2020-11-18doi:10.1101/2020.11.18.388819Cold Spring Harbor Laboratory Press2020-11-18
<![CDATA[
Sleeping ribosomes: bacterial signaling triggers RaiA mediated persistence to aminoglycosides.
]]>
https://biorxiv.org/cgi/content/short/2020.11.27.401281v1?rss=1"
Lang, M.Krin, E.Korlowski, C.Sismeiro, O.Varet, H.Coppee, J.-Y.Mazel, D.Baharoglu, Z.2020-11-27doi:10.1101/2020.11.27.401281Cold Spring Harbor Laboratory Press2020-11-27
<![CDATA[
The interplay between the bacterial capsule and mobile genetic elements determines direction and intensity of gene flux in Klebsiella pneumoniae.
]]>
https://biorxiv.org/cgi/content/short/2020.12.09.417816v1?rss=1"
Haudiquet, M.Buffet, A.Rendueles, O.Rocha, E. P. C.2020-12-09doi:10.1101/2020.12.09.417816Cold Spring Harbor Laboratory Press2020-12-09
<![CDATA[
Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses
]]>
https://biorxiv.org/cgi/content/short/2020.12.17.423082v1?rss=1"
Llibre, A.Smith, N.Rouilly, V.Musvosvi, M.Nemes, E.Posseme, C.Mabwe, S.Charbit, B.Kimbung Mbandi, S.Filander, E.Africa, H.Saint-Andre, V.Bondet, V.Bost, P.Mulenga, H.Bilek, N.Albert, M. L.Scriba, T. J.Duffy, D.2020-12-17doi:10.1101/2020.12.17.423082Cold Spring Harbor Laboratory Press2020-12-17
<![CDATA[
Cohesin regulates homology search during recombinational DNA repair
]]>
https://biorxiv.org/cgi/content/short/2020.12.17.423195v1?rss=1"
Piazza, A.Bordelet, H.Dumont, A.Thierry, A.Savocco, J.Girard, F.Koszul, R.2020-12-17doi:10.1101/2020.12.17.423195Cold Spring Harbor Laboratory Press2020-12-17
<![CDATA[
Long-range GABAergic projections contribute to cortical feedback control of sensory processing.
]]>
https://biorxiv.org/cgi/content/short/2020.12.19.423599v1?rss=1"
Mazo, C.Saha, S.Nissant, A.Peroni, E.Lledo, P.-M.Lepousez, G.2020-12-20doi:10.1101/2020.12.19.423599Cold Spring Harbor Laboratory Press2020-12-20
<![CDATA[
Colonization of dermal arterioles by Neisseria meningitidis provides a safe haven from neutrophils
]]>
https://biorxiv.org/cgi/content/short/2021.01.07.425689v1?rss=1"
Manriquez, V.Nivoit, P.Urbina, T.Echenique-Rivera, H.Melican, K.Flamant, P.Schmitt, T.Bruneval, P.Obino, D.Dumenil, G.2021-01-07doi:10.1101/2021.01.07.425689Cold Spring Harbor Laboratory Press2021-01-07
<![CDATA[
Listeria monocytogenes faecal carriage is common and driven by microbiota
]]>
https://biorxiv.org/cgi/content/short/2021.01.13.426560v1?rss=1"
Garcia-Garcera, M.Hafner, L.Burucoa, C.Moura, A.Pichon, M.Lecuit, M.2021-01-13doi:10.1101/2021.01.13.426560Cold Spring Harbor Laboratory Press2021-01-13
<![CDATA[
High-throughput phenotypic screen for genetic modifiers in patient-derived OPA1 mutant fibroblasts identifies PGS1 as a functional suppressor of mitochondrial fragmentation
]]>
https://biorxiv.org/cgi/content/short/2021.01.14.426579v1?rss=1"
Cretin, E.Thomas, P.Vimont, E.Tatsuta, T.Langer, T.Yu-Wai-Man, P.Reynier, P.Wai, T.2021-01-15doi:10.1101/2021.01.14.426579Cold Spring Harbor Laboratory Press2021-01-15
<![CDATA[
Prophage-encoded hotspots of bacterial immune systems
]]>
https://biorxiv.org/cgi/content/short/2021.01.21.427644v1?rss=1"
Rousset, F.Dowding, J.Bernheim, A.Rocha, E.Bikard, D.2021-01-22doi:10.1101/2021.01.21.427644Cold Spring Harbor Laboratory Press2021-01-22
<![CDATA[
Metabolic adaption to extracellular pyruvate triggers biofilm formation in Clostridioides difficile
]]>
https://biorxiv.org/cgi/content/short/2021.01.23.427917v1?rss=1"
Tremblay, Y. D.Durand, B. A.Hamiot, A.Martin-Verstraete, I.Oberkampf, M.Monot, M.Dupuy, B.2021-01-23doi:10.1101/2021.01.23.427917Cold Spring Harbor Laboratory Press2021-01-23
<![CDATA[
A novel SARS-CoV-2 related coronavirus in bats from Cambodia
]]>
https://biorxiv.org/cgi/content/short/2021.01.26.428212v1?rss=1"
Hul, V.Delaune, D.Karlsson, E. A.Hassanin, A.Ou Tey, P.Baidaliuk, A.Gambaro, F.Tu, V. T.Keatts, L.Mazet, J.Johnson, C.Buchy, P.Dussart, P.Goldstein, T.Simon-Loriere, E.Duong, V.2021-01-26doi:10.1101/2021.01.26.428212Cold Spring Harbor Laboratory Press2021-01-26
<![CDATA[
Interneuron activity-structural plasticity association is driven by context-dependent sensory experience
]]>
https://biorxiv.org/cgi/content/short/2021.01.28.428612v1?rss=1"
Saha, S.Meng, J. H.Riecke, H.Agoranos, G.Sailor, K. A.Lledo, P.-M.2021-01-28doi:10.1101/2021.01.28.428612Cold Spring Harbor Laboratory Press2021-01-28
<![CDATA[
The establishment of variant surface glycoprotein monoallelic expression revealed by single-cell RNA-seq of Trypanosoma brucei in the tsetse fly salivary glands.
]]>
https://biorxiv.org/cgi/content/short/2021.03.01.433049v1?rss=1"
Hutchinson, S.Foulon, S.Crouzols, A.Menafra, R.Rotureau, B.Griffiths, A. D.Bastin, P.2021-03-01doi:10.1101/2021.03.01.433049Cold Spring Harbor Laboratory Press2021-03-01
<![CDATA[
Deep learning from phylogenies to uncover the transmission dynamics of epidemics
]]>
https://biorxiv.org/cgi/content/short/2021.03.11.435006v1?rss=1"
Voznica, J.Zhukova, A.Boskova, V.Saulnier, E.Lemoine, F.Moslonka-Lefebvre, M.Gascuel, O.2021-03-12doi:10.1101/2021.03.11.435006Cold Spring Harbor Laboratory Press2021-03-12
<![CDATA[
MicroMator: Open and Flexible Software for Reactive Microscopy
]]>
https://biorxiv.org/cgi/content/short/2021.03.12.435206v1?rss=1"
Fox, Z. R.Fletcher, S.Fraisse, A.Aditya, C.Sosa-Carrillo, S.Gilles, S.Bertaux, F.Ruess, J.Batt, G.2021-03-13doi:10.1101/2021.03.12.435206Cold Spring Harbor Laboratory Press2021-03-13
<![CDATA[
A Multiscale Immuno-Oncology on-Chip System (MIOCS) establishes that collective T cell behaviors govern tumor regression
]]>
https://biorxiv.org/cgi/content/short/2021.03.23.435334v1?rss=1"
Ronteix, G.Jain, S.Angely, C.Cazaux, M.Khazen, R.Bousso, P.Baroud, C.2021-03-23doi:10.1101/2021.03.23.435334Cold Spring Harbor Laboratory Press2021-03-23
<![CDATA[
Comparative genome analysis using sample-specific string detection in accurate long reads
]]>
https://biorxiv.org/cgi/content/short/2021.03.23.436571v1?rss=1"
98%) reported across pairs or trios of WGS samples using accurate long reads (e.g., PacBio HiFi data).
AvailabilityThe proposed tool is publicly available at https://github.com/Parsoa/PingPong.
]]>Khorsand, P.Denti, L.Bonizzoni, P.Chikhi, R.Hormozdiari, F.2021-03-23doi:10.1101/2021.03.23.436571Cold Spring Harbor Laboratory Press2021-03-23
<![CDATA[
Interaction of the TonB dependent transporter HasR with its cognate TonB-like protein HasB in a membrane environment
]]>
https://biorxiv.org/cgi/content/short/2021.04.21.440789v1?rss=1"
Somboon, K.Melling, O.Lejeune, M.M.S. Pinheiro, G.Paquelin, A.Bardiaux, B.Nilges, M.Delepelaire, P.Khalid, S.Izadi-Pruneyre, N.2021-04-22doi:10.1101/2021.04.21.440789Cold Spring Harbor Laboratory Press2021-04-22
<![CDATA[
Smc3 acetylation, Pds5 and Scc2 control the translocase activity that establishes cohesin dependent chromatin loops
]]>
https://biorxiv.org/cgi/content/short/2021.04.21.440823v1?rss=1"
Bastie, N.Chapard, C.Dauban, L.Gadal, O.Beckouet, F.Koszul, R.2021-04-22doi:10.1101/2021.04.21.440823Cold Spring Harbor Laboratory Press2021-04-22
<![CDATA[
Morphogenesis of a complex glial niche requires an interplay between cellular growth and fusion
]]>
https://biorxiv.org/cgi/content/short/2021.05.09.443326v1?rss=1"
RUJANO, M. A.BRIAND, D.DELIC, B.SPEDER, P.2021-05-10doi:10.1101/2021.05.09.443326Cold Spring Harbor Laboratory Press2021-05-10
<![CDATA[
Diversity, taxonomy and evolution of archaeal viruses of the class Caudoviricetes
]]>
https://biorxiv.org/cgi/content/short/2021.05.26.445827v1?rss=1"
Liu, Y.Demina, T. A.Roux, S.Aiewsakun, P.Kazlauskas, D.Simmonds, P.Prangishvili, D.Oksanen, H. M.Krupovic, M.2021-05-26doi:10.1101/2021.05.26.445827Cold Spring Harbor Laboratory Press2021-05-26
<![CDATA[
An ancient divide in outer membrane tethering systems in Bacteria
]]>
https://biorxiv.org/cgi/content/short/2021.05.31.446380v1?rss=1"
Witwinowski, J.Sartori-Rupp, A.Taib, N.Pende, N.Tham, T. N.Poppleton, D.Ghigo, J.-M.Beloin, C.Gribaldo, S.2021-05-31doi:10.1101/2021.05.31.446380Cold Spring Harbor Laboratory Press2021-05-31
<![CDATA[
TDFragMapper: a visualization tool for evaluating experimental parameters in top-down proteomics
]]>
https://biorxiv.org/cgi/content/short/2021.06.03.446879v1?rss=1"
Dhenin, J. S.Borges Lima, D.Dupre, M.Chamot-Rooke, J.2021-06-03doi:10.1101/2021.06.03.446879Cold Spring Harbor Laboratory Press2021-06-03
<![CDATA[
Bacteroides thetaiotaomicron uses a widespread extracellular DNase to promote bile-dependent biofilm formation
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https://biorxiv.org/cgi/content/short/2021.06.04.447082v1?rss=1"
BECHON, N.MIHAJLOVIC, J.LOPES, A.-A.VENDRELL-FERNANDEZ, S.DESCHAMPS, J.BRIANDET, R.SISMEIRO, O.MARTIN-VERSTRAETE, I.DUPUY, B.GHIGO, J.-M.2021-06-04doi:10.1101/2021.06.04.447082Cold Spring Harbor Laboratory Press2021-06-04
<![CDATA[
Population structure analysis and laboratory monitoring of Shigella with a standardised core-genome multilocus sequence typing scheme: a validation study
]]>
https://biorxiv.org/cgi/content/short/2021.06.08.447214v1?rss=1"
Yassine, I.Lefevre, S.Hansen, E. E.Ruckly, C.Carle, I.Lejay-Collin, M.Fabre, L.Rafei, R.Clermont, D.Pardos de la Gandara, M.Dabboussi, F.Thomson, N. R.Weill, F.-X.2021-06-08doi:10.1101/2021.06.08.447214Cold Spring Harbor Laboratory Press2021-06-08
<![CDATA[
A light tunable differentiation system for the creation and control of consortia in yeast
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https://biorxiv.org/cgi/content/short/2021.06.09.447744v1?rss=1"
Aditya, C.Bertaux, F.Batt, G.Ruess, J.2021-06-09doi:10.1101/2021.06.09.447744Cold Spring Harbor Laboratory Press2021-06-09
<![CDATA[
Constitutive IFNα protein production in bats
]]>
https://biorxiv.org/cgi/content/short/2021.06.21.449208v1?rss=1"
Bondet, V.Le Baut, M.Le Poder, S.Lecu, A.Petit, T.Wedlarski, R.Duffy, D.Le Roux, D.2021-06-22doi:10.1101/2021.06.21.449208Cold Spring Harbor Laboratory Press2021-06-22
<![CDATA[
H3K9 tri-methylation at Nanog times differentiation commitment and enables the acquisition of primitive endoderm fate
]]>
https://biorxiv.org/cgi/content/short/2021.06.22.449256v1?rss=1"
Dubois, A.Vincenti, L.Vandormael-Pournin, S.Cohen-Tannoudji, M.Navarro, P.2021-06-22doi:10.1101/2021.06.22.449256Cold Spring Harbor Laboratory Press2021-06-22
<![CDATA[
A model-based approach to characterize enzyme-mediated response to antibiotic treatments: going beyond the SIR classification
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https://biorxiv.org/cgi/content/short/2021.07.16.452741v1?rss=1"
Andreani, V.You, L.Glaser, P.Batt, G.2021-07-17doi:10.1101/2021.07.16.452741Cold Spring Harbor Laboratory Press2021-07-17
<![CDATA[
Using single-cell models to predict the functionality of synthetic circuits at the population scale
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https://biorxiv.org/cgi/content/short/2021.08.03.454887v1?rss=1"
Aditya, C.Bertaux, F.Batt, G.Ruess, J.2021-08-04doi:10.1101/2021.08.03.454887Cold Spring Harbor Laboratory Press2021-08-04
<![CDATA[
Acetylation regulates the oligomerization state and activity of RNase J, the major ribonuclease of Helicobacter pylori
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https://biorxiv.org/cgi/content/short/2021.08.09.455701v1?rss=1"
Tejada-Arranz, a.Bouilloux-Lafont, M.PEI, X.-Y.Douche, T.Matondo, M.Williams, A.Raynal, B.Luisi, B.DE REUSE, H.2021-08-09doi:10.1101/2021.08.09.455701Cold Spring Harbor Laboratory Press2021-08-09
<![CDATA[
Parameter inference for stochastic biochemical models from perturbation experiments parallelised at the single cell level
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https://biorxiv.org/cgi/content/short/2021.08.24.457516v1?rss=1"
Davidovic, A.Chait, R.Batt, G.Ruess, J.2021-08-26doi:10.1101/2021.08.24.457516Cold Spring Harbor Laboratory Press2021-08-26
<![CDATA[
β-glucan-induced innate immune memory distinctively affects macrophage activation in response to differential environmental cues
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https://biorxiv.org/cgi/content/short/2021.08.30.458241v1?rss=1"
Piffer, A. C.Camilli, G.Bohm, M.Lavenir, R.Quintin, J.2021-09-01doi:10.1101/2021.08.30.458241Cold Spring Harbor Laboratory Press2021-09-01
<![CDATA[
Awake perception is associated with dedicated neuronal assemblies in cerebral cortex
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https://biorxiv.org/cgi/content/short/2021.08.31.458322v1?rss=1"
Filipchuk, A.Destexhe, A.Bathellier, B.2021-09-01doi:10.1101/2021.08.31.458322Cold Spring Harbor Laboratory Press2021-09-01
<![CDATA[
Bringing TrackMate in the era of machine-learning and deep-learning.
]]>
https://biorxiv.org/cgi/content/short/2021.09.03.458852v1?rss=1"
Ershov, D.Phan, M.-S.Pylvänäinen, J. W.Rigaud, S. U.Le Blanc, L.Charles-Orszag, A.Conway, J. R. W.Laine, R. F.Roy, N. H.Bonazzi, D.Dumenil, G.Jacquemet, G.Tinevez, J.-Y.2021-09-03doi:10.1101/2021.09.03.458852Cold Spring Harbor Laboratory Press2021-09-03
<![CDATA[
Identification of fetal liver stromal subsets in spectral cytometry using the parameter autofluorescence
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https://biorxiv.org/cgi/content/short/2021.09.29.462345v1?rss=1"
Peixoto, M.Soares-da-Silva, F.Schmutz, S.Mailhe, M.-P.Novault, S.Cumano, A.Ait Mansour, C.2021-10-01doi:10.1101/2021.09.29.462345Cold Spring Harbor Laboratory Press2021-10-01
<![CDATA[
Microtubule disassembly by caspases is the rate-limiting step of cell extrusion
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https://biorxiv.org/cgi/content/short/2021.10.15.464503v1?rss=1"
Villars, A.Matamoro-Vidal, A.Levillayer, F.Levayer, R.2021-10-15doi:10.1101/2021.10.15.464503Cold Spring Harbor Laboratory Press2021-10-15
<![CDATA[
Mitochondrial fission process 1 (MTFP1) controls bioenergetic efficiency and prevents inflammatory cardiomyopathy and heart failure in mice
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https://biorxiv.org/cgi/content/short/2021.10.21.465262v1?rss=1"
Donnarumma, E.Kohlhaas, M.Vimont, E.Kornobis, E.Chaze, T.Gia Giaetto, Q.Matondo, M.Moya-Nilges, M.Maack, C.Wai, T.2021-10-22doi:10.1101/2021.10.21.465262Cold Spring Harbor Laboratory Press2021-10-22
<![CDATA[
In-vitro cellular reprogramming to model gonad development and its disorders
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https://biorxiv.org/cgi/content/short/2021.10.22.465384v1?rss=1"
Gonen, N.Eozenou, C.Mitter, R.Bernardo, A.Chervova, A.Frachon, E.Commere, P.-H.Mazen, I.Gobaa, S.McElreavey, K.Lovell-Badge, R.Bashamboo, A.2021-10-24doi:10.1101/2021.10.22.465384Cold Spring Harbor Laboratory Press2021-10-24
<![CDATA[
Quantification of breeding sites parameters in shaping bacterial communities in Aedes aegypti (Diptera: Culicidae).
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https://biorxiv.org/cgi/content/short/2021.10.24.465617v1?rss=1"
Guimond, J.Hery, L.Guidez, A.Durand, A.-A.Delannay, C.Issaly, J.Raffestin, S.Nigro, J.Vega-Rua, A.Constant, P.Guertin, C.Dusfour, I.2021-10-24doi:10.1101/2021.10.24.465617Cold Spring Harbor Laboratory Press2021-10-24
<![CDATA[
Chromosome-scale assemblies of Acanthamoeba castellanii genomes provide insights into Legionella pneumophila infection-related chromatin re-organization
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https://biorxiv.org/cgi/content/short/2021.10.26.465878v1?rss=1"
Matthey-Doret, C.Colp, M. J.Escoll, P.Thierry, A.Curtis, B.Sarrasin, M.Gray, M. W.Lang, B. F.Archibald, J. M.Buchrieser, C.Koszul, R.2021-10-26doi:10.1101/2021.10.26.465878Cold Spring Harbor Laboratory Press2021-10-26
<![CDATA[
Spatial dynamics and vaccine-induced fitness changes of Bordetella pertussis
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https://biorxiv.org/cgi/content/short/2021.11.01.466439v1?rss=1"
Lefrancq, N.Bouchez, V.Fernandes, N.Barkoff, A.-M.Bosch, T.Dalby, T.Akerlund, T.Fabianova, K.Vestrheim, D. F.Fry, N. K.Gonzalez-Lopez, J. J.Gullsby, K.Habington, A.He, Q.Litt, D.Martini, H.Pierard, D.Stefanelli, P.Stegger, M. K.Zavadilov, J.Armatys, N.Landier, A.Guillot, S.Hong, S. L.Lemey, P.Parkhill, J.Toubiana, J.Cauchemez, S.Salje, H.Brisse, S.2021-11-01doi:10.1101/2021.11.01.466439Cold Spring Harbor Laboratory Press2021-11-01
<![CDATA[
Evolution of plasmid mobility: origin and fate of non-conjugative plasmids
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https://biorxiv.org/cgi/content/short/2021.12.10.472114v1?rss=1"
Coluzzi, C.Garcillan-Barcia, M. d. P.de la Cruz, F.Rocha, E. P. C.2021-12-11doi:10.1101/2021.12.10.472114Cold Spring Harbor Laboratory Press2021-12-11
<![CDATA[
PTEN inhibits AMPK to control collective migration
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https://biorxiv.org/cgi/content/short/2021.12.13.472380v1?rss=1"
PEGLION, F.Capuana, L.Perfettini, I.braithwaite, B.Llense, F.Quissac, E.Forsberg-Nilsson, K.Etienne-Manneville, s.2021-12-14doi:10.1101/2021.12.13.472380Cold Spring Harbor Laboratory Press2021-12-14
<![CDATA[
A highly sensitive cell-based luciferase assay for high-throughput automated screening of SARS-CoV-2 nsp5/3CLpro inhibitors
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https://biorxiv.org/cgi/content/short/2021.12.18.473303v1?rss=1"
Chen, K.-Y.Krischuns, T.Ortega Varga, L.Harigua-Souiai, E.Paisant, S.Zettor, A.Chiaravalli, J.Courtney, D.O'Brien, A.Baker, S.Isel, C.Agou, F.Jacob, Y.Blondel, A.Naffakh, N.2021-12-21doi:10.1101/2021.12.18.473303Cold Spring Harbor Laboratory Press2021-12-21
<![CDATA[
Caveolae promote successful abscission by controlling intercellular bridge tension during cytokinesis
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https://biorxiv.org/cgi/content/short/2022.01.04.474800v1?rss=1"
ANDRADE, V.Bai, J.GUPTA, N.Jimenez, A.-J.Delevoye, C.Lamaze, C.Echard, A.2022-01-04doi:10.1101/2022.01.04.474800Cold Spring Harbor Laboratory Press2022-01-04
<![CDATA[
Anti-thrombotic treatment enhances antibiotic efficiency in a humanized model of meningococcemia
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https://biorxiv.org/cgi/content/short/2022.01.10.475613v1?rss=1"
Corre, J.-P.Obino, D.Nivoit, P.Yatim, A.Schmitt, T.Dumenil, G.2022-01-11doi:10.1101/2022.01.10.475613Cold Spring Harbor Laboratory Press2022-01-11
<![CDATA[
Griottes: a generalist tool for network generation from segmented tissue images
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https://biorxiv.org/cgi/content/short/2022.01.14.476345v1?rss=1"
Ronteix, G.Bonnet, V.Sart, S.Sobel, J.Esposito, E.Baroud, C.2022-01-14doi:10.1101/2022.01.14.476345Cold Spring Harbor Laboratory Press2022-01-14
<![CDATA[
Multilevel Development of Cognitive Abilities in an Artificial Neural Network
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https://biorxiv.org/cgi/content/short/2022.01.24.477526v1?rss=1"
Volzhenin, K.Changeux, J.-P.Dumas, G.2022-01-25doi:10.1101/2022.01.24.477526Cold Spring Harbor Laboratory Press2022-01-25
<![CDATA[
Improved structural variant discovery in hard-to-call regions using sample-specific string detection from accurate long reads
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https://biorxiv.org/cgi/content/short/2022.02.12.480198v1?rss=1"
Denti, L.Khorsand, P.Bonizzoni, P.Hormozdiari, F.Chikhi, R.2022-02-14doi:10.1101/2022.02.12.480198Cold Spring Harbor Laboratory Press2022-02-14
<![CDATA[
Nitric oxide signaling controls collective contractions in a colonial choanoflagellate
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https://biorxiv.org/cgi/content/short/2022.02.14.480389v1?rss=1"
Reyes-Rivera, J.Wu, Y.Guthrie, B. G. H.Marletta, M. A.King, N.Brunet, T.2022-02-14doi:10.1101/2022.02.14.480389Cold Spring Harbor Laboratory Press2022-02-14
<![CDATA[
Salient 40 Hz sounds probe affective aversion and neural excitability
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https://biorxiv.org/cgi/content/short/2022.02.26.482077v1?rss=1"
Schneefeld, F.Doelling, K. D.Marchesotti, S.Schwartz, S.Igloi, K.Giraud, A.-L.Arnal, L. H.2022-03-01doi:10.1101/2022.02.26.482077Cold Spring Harbor Laboratory Press2022-03-01
<![CDATA[
Single-cell microfluidic analysis unravels individual cellular fates during Double-Strand Break Repair
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https://biorxiv.org/cgi/content/short/2022.03.10.483811v1?rss=1"
Vertti-Quintero, N.Levien, E.Poggi, L.Amir, A.Richard, G.-F.Baroud, C. N.2022-03-12doi:10.1101/2022.03.10.483811Cold Spring Harbor Laboratory Press2022-03-12
<![CDATA[
Patterned apoptosis modulates local growth and tissue shape in a fast-growing epithelium
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https://biorxiv.org/cgi/content/short/2022.03.11.484029v1?rss=1"
Matamoro-Vidal, A.Cumming, T.Davidovic, A.Levayer, R.2022-03-14doi:10.1101/2022.03.11.484029Cold Spring Harbor Laboratory Press2022-03-14
<![CDATA[
Splenic clearance of rigid erythrocytes as an inherited mechanism for splenomegaly and natural resistance to malaria
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https://biorxiv.org/cgi/content/short/2022.03.21.485136v1?rss=1"
Henry, B.Volle, G.Akpovi, H.Gineau, L.Roussel, C.Ndour, P. A.Tossou, F.Suarez, F.Palstra, F.Fricot, A.Chambrion, C.Solinc, J.Nguyen, J.Gare, M.Aussenac, F.Cottart, C. H.Keyser, C.Adamou, R.Tichit, M.Hardy, D.Fievet, N.Clain, J.Garcia, A.Courtin, D.Hermine, O.Sabbagh, A.Buffet, P.2022-03-21doi:10.1101/2022.03.21.485136Cold Spring Harbor Laboratory Press2022-03-21
<![CDATA[
Humanized mice for sustained Plasmodium vivax blood-stage infection and transmission
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https://biorxiv.org/cgi/content/short/2022.03.22.485265v1?rss=1"
Luiza-Batista, C.Thiberge, S.Serra-Hassoun, M.Garcia, S.Nardella, F.Claes, A.Nicolete, V. C.Commere, P.-H.Silva-Mancio, L.Ferreira, M. U.Scherf, A.Garcia, S.2022-03-22doi:10.1101/2022.03.22.485265Cold Spring Harbor Laboratory Press2022-03-22
<![CDATA[
Enhanced performance in perceptual decision making task without deprivation in mice using medial forebrain bundle stimulation
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https://biorxiv.org/cgi/content/short/2022.03.29.486230v1?rss=1"
Verdier, A.Aldanondo, A.Bathellier, B.Bagur, S.2022-03-30doi:10.1101/2022.03.29.486230Cold Spring Harbor Laboratory Press2022-03-30
<![CDATA[
Extracting multiple surfaces from 3D microscopy images in complex biological tissues with the Zellige software tool.
]]>
https://biorxiv.org/cgi/content/short/2022.04.05.485876v1?rss=1"
Trebeau, C.Boutet de Monvel, J.Altay, G.Tinevez, J.-Y.Etournay, R.2022-04-07doi:10.1101/2022.04.05.485876Cold Spring Harbor Laboratory Press2022-04-07
<![CDATA[
DNA methylome combined with chromosome cluster-oriented analysis provides an early signature for cutaneous melanoma aggressiveness
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https://biorxiv.org/cgi/content/short/2022.04.11.487909v1?rss=1"
Carrier, A.Desjobert, C.Ponger, L.Lamant, L.Bustos, M.Torres-Ferreira, J.Henrique, R.Jeronimo, C.Lanfrancone, L.Delmas, A.Favre, G.Delaunay, A.Busato, F.Hoon, D. S. B.Tost, J.Etievant, C.Riond, J.Arimondo, P. B.2022-04-12doi:10.1101/2022.04.11.487909Cold Spring Harbor Laboratory Press2022-04-12
<![CDATA[
Viral origin of eukaryotic type IIA DNA topoisomerases
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https://biorxiv.org/cgi/content/short/2022.04.12.488027v1?rss=1"
Guglielmini, J.Gaia, M.Da Cunha, V.Criscuolo, A.Krupovic, M.Forterre, P.2022-04-12doi:10.1101/2022.04.12.488027Cold Spring Harbor Laboratory Press2022-04-12
<![CDATA[
HARIBOSS: a curated database of RNA-small molecules structures to aid rational drug design
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https://biorxiv.org/cgi/content/short/2022.05.17.492306v1?rss=1"
Panei, F. P.Torchet, R.Menager, H.Gkeka, P.Bonomi, M.2022-05-19doi:10.1101/2022.05.17.492306Cold Spring Harbor Laboratory Press2022-05-19
<![CDATA[
Chromosome folding and prophage activation reveal gut-specific genome dynamics of bacteria in the OMM12 consortium
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https://biorxiv.org/cgi/content/short/2022.05.18.492453v1?rss=1"
Lamy-Besnier, Q.Bignaud, A.Garneau, J.Titecat, M.Conti, D.Von Strempel, A.Monot, M.Stecher, B.Koszul, R.Debarbieux, L.Marbouty, M.2022-05-18doi:10.1101/2022.05.18.492453Cold Spring Harbor Laboratory Press2022-05-18
<![CDATA[
The spike-stabilizing D614G mutation interacts with S1/S2 cleavage site mutations to promote the infectious potential of SARS-CoV-2 variants
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https://biorxiv.org/cgi/content/short/2022.05.20.492832v1?rss=1"
Gellenoncourt, S.Saunders, N.Robinot, R.Auguste, L.Rajah, M. M.Kervevan, J.Jeger-Madiot, R.Staropoli, I.Planchais, C.Mouquet, H.Buchrieser, J.Schwartz, O.Chakrabarti, L. A.2022-05-20doi:10.1101/2022.05.20.492832Cold Spring Harbor Laboratory Press2022-05-20
<![CDATA[
Establishment of a colony of Anopheles darlingi from French Guiana for vector competence studies on malaria transmission
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https://biorxiv.org/cgi/content/short/2022.05.24.493327v1?rss=1"
Puchot, N.Lecoq, M.-T.Carinci, R.Duchemin, J.-B.Gendrin, M.Bourgouin, C.2022-05-26doi:10.1101/2022.05.24.493327Cold Spring Harbor Laboratory Press2022-05-26
<![CDATA[
Bacterial capsular polysaccharides with antibiofilm activity share common biophysical and electrokinetic properties
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https://biorxiv.org/cgi/content/short/2022.05.27.493690v1?rss=1"
BAYARD-BERNAL, J.THIEBAUD, J.BROSSAUD, M.BEAUSSART, A.CAILLET, C.WALDVOGEL, Y.TRAVIER, L.LETOFFE, S.FONTAINE, T.ROKBI, B.TALAGA, P.BELOIN, C.MISTRETTA, N.DUVAL, J. F. L.GHIGO, J.-M.2022-05-27doi:10.1101/2022.05.27.493690Cold Spring Harbor Laboratory Press2022-05-27
<![CDATA[
Illumination of a progressive allosteric mechanism mediating the glycine receptor activation
]]>
https://biorxiv.org/cgi/content/short/2022.06.04.494798v1?rss=1"
Shi, S.Lefebvre, S. N.Peverini, L.Cerdan, A. H.Gielen, M.Changeux, J.-P.CECCHINI, M.Corringer, P.-J.2022-06-05doi:10.1101/2022.06.04.494798Cold Spring Harbor Laboratory Press2022-06-05
<![CDATA[
Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system
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https://biorxiv.org/cgi/content/short/2022.07.16.500195v1?rss=1"
Dazzoni, R.Li, Y.Lopez-Castilla, A.Brier, S.Mechaly, A.Cordier, F.Haouz, A.Nilges, M.Francetic, O.Bardiaux, B.Izadi-Pruneyre, N.2022-07-16doi:10.1101/2022.07.16.500195Cold Spring Harbor Laboratory Press2022-07-16
<![CDATA[
DNA-binding mechanism and evolution of Replication Protein A
]]>
https://biorxiv.org/cgi/content/short/2022.07.20.500673v1?rss=1"
Madru, C.Martinez-Carranza, M.Laurent, S.Alberti, A. C.Chevreuil, M.Raynal, B.Haouz, A.Le Meur, R. A.Delarue, M.Flament, D.Kuprovic, M.Legrand, P.Sauguet, L.2022-07-21doi:10.1101/2022.07.20.500673Cold Spring Harbor Laboratory Press2022-07-21
<![CDATA[
Escherichia coli membrane microdomain SPFH protein HflC interacts with YajC and contributes to aminoglycoside and oxidative stress tolerance
]]>
https://biorxiv.org/cgi/content/short/2022.07.25.501378v1?rss=1"
Wessel, A. K.Yoshii, Y.Reder, A.Boudjemaa, R.Szczesna, M.Betton, J.-M.Bernal-Bayard, J.Beloin, C.Lopez, D.Volker, U.Ghigo, J.-M.2022-07-25doi:10.1101/2022.07.25.501378Cold Spring Harbor Laboratory Press2022-07-25
<![CDATA[
Unexpected higher convergence of human-great ape enteric viromes in central African forest than in a European zoo: A One Health analysis
]]>
https://biorxiv.org/cgi/content/short/2022.07.29.501976v1?rss=1"
Narat, V.Salmona, M.Kampo, M.Heyer, T.Mercier-Delarue, S.Ranger, N.Rupp, S.Ambata, P.Njouom, R.Simon, F.Le Goff, J.Giles-Vernick, T.2022-07-29doi:10.1101/2022.07.29.501976Cold Spring Harbor Laboratory Press2022-07-29
<![CDATA[
Arp2/3 inhibition switches Eps8's network associations to favour longer actin filament formation necessary for tunneling nanotubes
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https://biorxiv.org/cgi/content/short/2022.08.24.504515v1?rss=1"
Henderson, J. M.Ljubojevic, N.Chaze, T.Castaneda, D.Battistella, A.Giai Gianetto, Q.Matondo, M.Descroix, S.Bassereau, P.Zurzolo, C.2022-08-24doi:10.1101/2022.08.24.504515Cold Spring Harbor Laboratory Press2022-08-24
<![CDATA[
Hemisynthetic derivatives of the natural alkaloid trilobine are fast-acting antimalarial compounds with sustained activity in multi-drug resistant P. falciparum isolates
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https://biorxiv.org/cgi/content/short/2022.08.30.505923v1?rss=1"
Nardella, F.Dobrescu, I.Hassan, H.Rodrigues, F.Thiberge, S.Mancio, L.Tafit, A.Jallet, C.Cadet-Daniel, V.Goussin, S.Lorthiois, A.Menon, Y.Molinier, N.Pechalrieu, D.Long, C.Sautel, F.Matondo, M.Duchateau, M.Medard, G.Witkowski, B.Scherf, A.Halby, L.Arimondo, P. B.2022-09-02doi:10.1101/2022.08.30.505923Cold Spring Harbor Laboratory Press2022-09-02
<![CDATA[
Inflammation drives age-induced loss of tissue resident macrophages
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https://biorxiv.org/cgi/content/short/2022.10.02.510513v1?rss=1"
Ade, K.Coronilla, J. S.Obino, D.Weinberger, T.Kaiser, C.Mella, S.Chen, C.Katsimpardi, L.Werts, C.Dardenne, P.Lallemand, Y.Gomez-Perdiguero, E.2022-10-05doi:10.1101/2022.10.02.510513Cold Spring Harbor Laboratory Press2022-10-05
<![CDATA[
A corset of adhesions during development establishes individual neural stem cell niches and controls adult behaviour
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https://biorxiv.org/cgi/content/short/2022.10.04.510893v1?rss=1"
Banach-Latapy, A.Rincheval, V.Briand, D.Guenal, I.Speder, P.2022-10-05doi:10.1101/2022.10.04.510893Cold Spring Harbor Laboratory Press2022-10-05
<![CDATA[
SARS-CoV-2 infection in domestic rats after transmission from their infected owner
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https://biorxiv.org/cgi/content/short/2022.10.13.512053v1?rss=1"
Montagutelli, X.Decaudin, B.Beretta, M.Mouquet, H.Simon-Loriere, E.2022-10-13doi:10.1101/2022.10.13.512053Cold Spring Harbor Laboratory Press2022-10-13
<![CDATA[
Maximizing protein production by keeping cells at optimal secretory stress levels using real-time control approaches
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https://biorxiv.org/cgi/content/short/2022.11.02.514931v1?rss=1"
Sosa-Carrillo, S.Galez, H.Napolitano, S.Bertaux, F.Batt, G.2022-11-04doi:10.1101/2022.11.02.514931Cold Spring Harbor Laboratory Press2022-11-04
<![CDATA[
Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti
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https://biorxiv.org/cgi/content/short/2022.11.14.516413v1?rss=1"
Merkling, S. H.Crist, A. B.Henrion-Lacritick, A.Frangeul, L.Gausson, V.Blanc, H.Baidaliuk, A.Saleh, M.-C.Lambrechts, L.2022-11-15doi:10.1101/2022.11.14.516413Cold Spring Harbor Laboratory Press2022-11-15
<![CDATA[
Mitotic bookmarking redundancy by nuclear receptors mediates robust post-mitotic reactivation of the pluripotency network.
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https://biorxiv.org/cgi/content/short/2022.11.28.518105v1?rss=1"
Chervova, A.Molliex, A.Baymaz, I.Papadopolou, T.Mueller, F.Hercul, E.Fournier, D.Dubos, A.Gaiani, N.Beli, P.Festuccia, N.Navarro, P.2022-11-28doi:10.1101/2022.11.28.518105Cold Spring Harbor Laboratory Press2022-11-28
<![CDATA[
Molecular mechanisms regulating the pH-dependent pr/E interaction in yellow fever virus.
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https://biorxiv.org/cgi/content/short/2022.12.06.519383v1?rss=1"
Crampon, E.Covernton, E.Vaney, M.-C.Dellarole, M.Sharma, A.Haouz, A.England, P.Lepault, J.Duquerroy, S.Rey, F. A.Barba Spaeth, G.2022-12-07doi:10.1101/2022.12.06.519383Cold Spring Harbor Laboratory Press2022-12-07
<![CDATA[
A multi-parameter optimization in middle-down analysis of monoclonal antibodies by LC-MS/MS
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https://biorxiv.org/cgi/content/short/2022.12.08.518878v1?rss=1"
Dhenin, J. S.Dupre, M.Druart, K.Krick, A.Mauriac, C.Chamot-Rooke, J.2022-12-08doi:10.1101/2022.12.08.518878Cold Spring Harbor Laboratory Press2022-12-08
<![CDATA[
Quinazoline-quinoline bisubstrate inhibitors target eukaryotic translation initiation factor 3 in Plasmodium falciparum
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https://biorxiv.org/cgi/content/short/2022.12.10.519887v1?rss=1"
Dobrescu, I.Hammam, E.Dziekan, J. M.Claës, A.Halby, L.Preiser, P.Bozdech, Z.Arimondo, P. B.Scherf, A.Nardella, F.2022-12-11doi:10.1101/2022.12.10.519887Cold Spring Harbor Laboratory Press2022-12-11
<![CDATA[
Emergence of a time-independent population code in auditory cortex enables sound categorization and discrimination learning
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https://biorxiv.org/cgi/content/short/2022.12.14.520391v1?rss=1"
Bagur, S.Bourg, J.Kempf, A.Tarpin, T.Bergaoui, K.Guo, Y.Ceballo, S.Schwenkgrub, J.Puel, J.-L.Bourien, J.Bathellier, B.2022-12-15doi:10.1101/2022.12.14.520391Cold Spring Harbor Laboratory Press2022-12-15
<![CDATA[
Exogenous chromosomes reveal how sequence composition drives chromatin assembly, activity, folding and compartmentalization
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https://biorxiv.org/cgi/content/short/2022.12.21.520625v1?rss=1"
Chapard, C.Meneu, L.Serizay, J.Routhier, E.Ruault, M.Bignaud, A.Gourgues, G.Lartigue, C.Piazza, A.Taddei, A.Beckouet, F.Mozziconacci, J.Koszul, R.2022-12-21doi:10.1101/2022.12.21.520625Cold Spring Harbor Laboratory Press2022-12-21
<![CDATA[
Proteomic landscape of tunneling nanotubes reveals CD9 and CD81 tetraspanins as key regulators
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https://biorxiv.org/cgi/content/short/2022.12.21.521537v1?rss=1"
Notario Manzano, R.Chaze, T.Rubinstein, E.Matondo, M.Zurzolo, C.Brou, C.2022-12-22doi:10.1101/2022.12.21.521537Cold Spring Harbor Laboratory Press2022-12-22
<![CDATA[
Apical size and deltaA expression predict adult neural stem cell decisions along lineage progression
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https://biorxiv.org/cgi/content/short/2022.12.26.521937v1?rss=1"
Mancini, L.Guirao, B.Ortica, S.Labusch, M.Cheysson, F.Bonnet, V.Phan, M. S.Herbert, S.Mahou, P.Menant, E.Bedu, S.Tinevez, J.-Y.Baroud, C.Beaurepaire, E.Bellaiche, Y.Bally-Cuif, L.Dray, N.2022-12-26doi:10.1101/2022.12.26.521937Cold Spring Harbor Laboratory Press2022-12-26
<![CDATA[
An original potentiating mechanism revealed by the cryoEM structures of the human α7 nicotinic receptor in complex with nanobodies
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https://biorxiv.org/cgi/content/short/2023.01.03.522595v1?rss=1"
Prevost, M. S.Barilone, N.Dejean de la Batie, G.Pons, S.Ayme, G.England, P.Gielen, M.Bontems, F.Pehau-Arnaudet, G.Maskos, U.Lafaye, P.Corringer, P.-J.2023-01-03doi:10.1101/2023.01.03.522595Cold Spring Harbor Laboratory Press2023-01-03
<![CDATA[
The genomic diversity of Taiwanese Austronesian groups: implications for the "Into and Out of Taiwan" models
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https://biorxiv.org/cgi/content/short/2023.01.09.523210v1?rss=1"
Liu, D.Ko, A. M.-S.Stoneking, M.2023-01-09doi:10.1101/2023.01.09.523210Cold Spring Harbor Laboratory Press2023-01-09
<![CDATA[
Fast 2-photon stimulation using holographic patterns
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https://biorxiv.org/cgi/content/short/2023.01.12.523269v1?rss=1"
Brunstein, M.Lubetzki, J.Li, W.Moutoussamy, C.Barral, J.2023-01-13doi:10.1101/2023.01.12.523269Cold Spring Harbor Laboratory Press2023-01-13
<![CDATA[
Basolateral amygdala circuits supporting negative emotional bias in a mouse model for depression
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https://biorxiv.org/cgi/content/short/2023.01.23.525169v1?rss=1"
Bigot, M.De Badts, C.-H.Benchetrit, A.Vicq, E.Moigneu, C.Meyrel, M.Wagner, S.Houenou, J.Lledo, P.-M.Henry, C.ALONSO, M.2023-01-23doi:10.1101/2023.01.23.525169Cold Spring Harbor Laboratory Press2023-01-23
<![CDATA[
Paired single-cell multi-omics data integration with Mowgli
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https://biorxiv.org/cgi/content/short/2023.02.02.526825v1?rss=1"
Huizing, G.-J.Deutschmann, I. M.Peyre, G.Cantini, L.2023-02-03doi:10.1101/2023.02.02.526825Cold Spring Harbor Laboratory Press2023-02-03
<![CDATA[
DeXtrusion: Automatic recognition of epithelial cell extrusion through machine learning in vivo
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https://biorxiv.org/cgi/content/short/2023.02.16.528845v1?rss=1"
Villars, A.Letort, G.Valon, L.Levayer, R.2023-02-16doi:10.1101/2023.02.16.528845Cold Spring Harbor Laboratory Press2023-02-16
<![CDATA[
Fast Identification of Optimal Monotonic Classifiers
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https://biorxiv.org/cgi/content/short/2023.02.22.529510v1?rss=1"
Fourquet, O.Krejca, M. S.Doerr, C.Schwikowski, B.2023-02-22doi:10.1101/2023.02.22.529510Cold Spring Harbor Laboratory Press2023-02-22
<![CDATA[
Neisseria leonis sp. nov. isolated from rabbits, reclassification of Uruburuella suis, Uruburuella testudinis, Kingella potus, Bergeriella denitrificans and Morococcus cerebrosus into Neisseria genus and reclassification of Neisseria shayeganii into Eikenella genus
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https://biorxiv.org/cgi/content/short/2023.02.24.529859v1?rss=1"
Boutroux, M.Favre-Rochex, S.Gorgette, O.Touak, G.Muhle, E.Chesneau, O.Clermont, D.Rahi, P.2023-02-24doi:10.1101/2023.02.24.529859Cold Spring Harbor Laboratory Press2023-02-24
<![CDATA[
Specific subcellular localization drives the different functions of CDC42 isoforms during migration
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https://biorxiv.org/cgi/content/short/2023.02.27.528078v1?rss=1"
Ravichandran, Y.Hanisch, J.Murray, K.Roca, V.Dingli, F.Loew, D.Sabatet, V.Boeda, B.Etienne-Manneville, S.2023-02-27doi:10.1101/2023.02.27.528078Cold Spring Harbor Laboratory Press2023-02-27
<![CDATA[
Integrative single-cell transcriptomics clarifies adult neurogenesis and macroglia evolution
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https://biorxiv.org/cgi/content/short/2023.02.27.530203v1?rss=1"
Morizet, D.Foucher, I.Alunni, A.Bally-Cuif, L.2023-02-27doi:10.1101/2023.02.27.530203Cold Spring Harbor Laboratory Press2023-02-27
<![CDATA[
Measuring single-cell susceptibility to antibiotics within monoclonal bacterial populations
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https://biorxiv.org/cgi/content/short/2023.03.08.531654v1?rss=1"
Le Quellec, L.Aristov, A.Guitierrez Ramos, S.Amselem, G.Bos, J.Baharoglu, Z.Mazel, D.Baroud, C.2023-03-09doi:10.1101/2023.03.08.531654Cold Spring Harbor Laboratory Press2023-03-09
<![CDATA[
Extraocular muscle stem cells exhibit distinct cellular properties associated with non-muscle molecular signatures
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https://biorxiv.org/cgi/content/short/2023.03.10.532049v1?rss=1"
Di Girolamo, D.Benavente-Diaz, M.Grimaldi, A.Thomas Lopes, P.Evano, B.Gioftsidi, S.Laville, V.Mella, S.Tajbakhsh, S.Comai, G.2023-03-10doi:10.1101/2023.03.10.532049Cold Spring Harbor Laboratory Press2023-03-10
<![CDATA[
Hsc70-4 mediates internalization of environmental dsRNA at the surface of Drosophila S2 cells
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https://biorxiv.org/cgi/content/short/2023.03.11.532206v1?rss=1"
Fletcher, S. J.Tome-Poderti, L.Mongelli, V.Frangeul, L.Blanc, H.Verdier, Y.Vinh, J.Saleh, M.-C.2023-03-11doi:10.1101/2023.03.11.532206Cold Spring Harbor Laboratory Press2023-03-11
<![CDATA[
Short-chain mono-carboxylates as negative allosteric modulators of GLIC, and impact of a pre-β5 strand (Loop {Omega}) double mutation on crotonate, not butyrate effect.
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https://biorxiv.org/cgi/content/short/2023.03.14.530991v1?rss=1"
Van Renterghem, C.Nemecz, A.Medjebeur, K.Corringer, P.-J.2023-03-15doi:10.1101/2023.03.14.530991Cold Spring Harbor Laboratory Press2023-03-15
<![CDATA[
The RBPome of influenza A virus mRNA reveals a role for TDP-43 in viral replication
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https://biorxiv.org/cgi/content/short/2023.03.21.533609v1?rss=1"
Dupont, M.Krischuns, T.Giai Gianetto, Q.Paisant, S.Bonazza, S.Brault, J.-B.Douche, T.Perez-Perri, J. I.Hentze, M. W.Cusack, S.Matondo, M.Isel, C.Courtney, D.Naffakh, N.2023-03-21doi:10.1101/2023.03.21.533609Cold Spring Harbor Laboratory Press2023-03-21
<![CDATA[
RavA-ViaA links Vibrio cholerae Cpx and Zra2 envelope stress to antibiotic response
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https://biorxiv.org/cgi/content/short/2023.04.24.538083v1?rss=1"
Krin, E.Carvalho, A.Lang, M.Babosan, A.Mazel, D.Baharoglu, Z.2023-04-24doi:10.1101/2023.04.24.538083Cold Spring Harbor Laboratory Press2023-04-24
<![CDATA[
Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis
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https://biorxiv.org/cgi/content/short/2023.04.26.538374v1?rss=1"
Patitucci, C.Hernandez Camacho, J. D.Vimont, E.Cokelaer, T.Chaze, T.Giai Giainetto, Q.Matondo, M.Gazi, A.Nemazanyy, I.Stroud, D. A.Hock, D. H.Donnarumma, E.Wai, T.2023-04-28doi:10.1101/2023.04.26.538374Cold Spring Harbor Laboratory Press2023-04-28
<![CDATA[
Analysis of in-patient evolution of Escherichia coli reveals potential links to relapse of bone and joint infections
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https://biorxiv.org/cgi/content/short/2023.05.10.540183v1?rss=1"
Thiriet Rupert, S.Josse, J.Perez Pascual, D.Tasse, J.Andre, C.Abad, L.Lebeaux, D.Ghigo, J.-M.Laurent, F.Beloin, C.2023-05-10doi:10.1101/2023.05.10.540183Cold Spring Harbor Laboratory Press2023-05-10
<![CDATA[
Torsion of the heart tube by shortage of progenitor cells : identification of Greb1l as a genetic determinant of criss-cross heart in mice
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https://biorxiv.org/cgi/content/short/2023.05.11.540418v1?rss=1"
Bernheim, S.Borgel, A.Le Garrec, J. F.Perthame, E.Desgrange, A.Krezel, W.Raimondi, F.Bonnet, D.Houyel, L.Meilhac, S.2023-05-11doi:10.1101/2023.05.11.540418Cold Spring Harbor Laboratory Press2023-05-11
<![CDATA[
A comparative genomics approach reveals a local genetic signature of Leishmania tropica in Morocco
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https://biorxiv.org/cgi/content/short/2023.05.25.542267v1?rss=1"
Talimi, H.Daoui, O.Bussotti, G.Mhaidi, I.Boland, A.Deleuze, J.-F.Fissoune, R.Spaeth, G. F.Lemrani, M.2023-05-25doi:10.1101/2023.05.25.542267Cold Spring Harbor Laboratory Press2023-05-25
<![CDATA[
Construction and representation of human pangenome graphs
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https://biorxiv.org/cgi/content/short/2023.06.02.542089v1?rss=1"
Andreace, F.Lechat, P.Dufresne, Y.Chikhi, R.2023-06-03doi:10.1101/2023.06.02.542089Cold Spring Harbor Laboratory Press2023-06-03
<![CDATA[
Molecular mechanisms reconstruction from single-cell multi-omics data with HuMMuS
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https://biorxiv.org/cgi/content/short/2023.06.09.543828v1?rss=1"
Trimbour, R.Deutschmann, I. M.Cantini, L.2023-06-09doi:10.1101/2023.06.09.543828Cold Spring Harbor Laboratory Press2023-06-09
<![CDATA[
Polygenic risk score prediction accuracy convergence
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https://biorxiv.org/cgi/content/short/2023.06.27.546518v1?rss=1"
Henches, L.Kim, J.Yang, Z.Rubinacci, S.Pires, G.Albinana, C.Boetto, C.Julienne, H.Frouin, A.Auvergne, A.Suzuki, Y.Djebali, S.Delaneau, O.Ganna, A.Vilhjalmsson, B.Prive, F.Aschard, H.2023-06-29doi:10.1101/2023.06.27.546518Cold Spring Harbor Laboratory Press2023-06-29
<![CDATA[
Spatial confinement of Trypanosoma brucei in microfluidic traps provides a new tool to study free swimming parasites
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https://biorxiv.org/cgi/content/short/2023.07.03.547584v1?rss=1"
De Niz, M.Frachon, E.Gobaa, S.Bastin, P.2023-07-03doi:10.1101/2023.07.03.547584Cold Spring Harbor Laboratory Press2023-07-03
<![CDATA[
High-dimensional spectral cytometry panels for whole blood immune phenotyping
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https://biorxiv.org/cgi/content/short/2023.07.17.549272v1?rss=1"
400 donors from the initial MI cohort.
]]>Dott, T.Culina, S.Chemali, R.Ait Mansour, C.Dubois, F.Jagla, B.Doisne, J. M.Rogge, L.Huetz, F.Jönsson, F.Commere, P.-H.Di Santo, J.Terrier, B.Quintana-Murci, L.Duffy, D.Hasan, M.Milieu Interieur Consortium,2023-07-18doi:10.1101/2023.07.17.549272Cold Spring Harbor Laboratory Press2023-07-18
<![CDATA[
Identification of the active mechanism of aminoglycoside entry in V. cholerae through characterization of sRNA ctrR, regulating carbohydrate utilization and transport.
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https://biorxiv.org/cgi/content/short/2023.07.19.549712v1?rss=1"
A. Pierle, S.Lang, M.Lopez-Igual, R.Krin, E.Fourmy, D.Kennedy, S. P.Val, M.-E.Baharoglu, Z.Mazel, D.2023-07-19doi:10.1101/2023.07.19.549712Cold Spring Harbor Laboratory Press2023-07-19
<![CDATA[
Bile-induced biofilm formation in Bacteroides thetaiotaomicron requires magnesium efflux by an RND pump
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https://biorxiv.org/cgi/content/short/2023.07.26.550638v1?rss=1"
LOPES, A.-A.DESCHAMPS, J.GEORGEAULT, S.COKELAER, T.BRIANDET, R.GHIGO, J.-M.2023-07-26doi:10.1101/2023.07.26.550638Cold Spring Harbor Laboratory Press2023-07-26
<![CDATA[
Deep estimation of the intensity and timing of selection from ancient genomes
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https://biorxiv.org/cgi/content/short/2023.07.27.550703v1?rss=1"
Laval, G.Patin, E.Quintana-Murci, L.Kerner, G.2023-07-28doi:10.1101/2023.07.27.550703Cold Spring Harbor Laboratory Press2023-07-28
<![CDATA[
Sister chromatid cohesion halts DNA loop expansion
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https://biorxiv.org/cgi/content/short/2023.07.31.551217v1?rss=1"
Bastie, N.Chapard, C.Nejmi, S.Mboumba, H.thierry, a.Beckouet, F.Koszul, R.2023-07-31doi:10.1101/2023.07.31.551217Cold Spring Harbor Laboratory Press2023-07-31
<![CDATA[
Uridine as a potentiator of aminoglycosides through activation of carbohydrate transporters
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https://biorxiv.org/cgi/content/short/2023.07.31.551273v1?rss=1"
Lang, M.Renard, S.El-Meouche, I.Amoura, A.Denamur, E.Brosschot, T.Ingersoll, M.Bacque, E.Mazel, D.Baharoglu, Z.2023-08-01doi:10.1101/2023.07.31.551273Cold Spring Harbor Laboratory Press2023-08-01
<![CDATA[
The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome
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https://biorxiv.org/cgi/content/short/2023.08.01.551436v1?rss=1"
Krischuns, T.Arragain, B.Isel, C.Paisant, S.Budt, M.Wolff, T.Cusack, S.Naffakh, N.2023-08-01doi:10.1101/2023.08.01.551436Cold Spring Harbor Laboratory Press2023-08-01
<![CDATA[
Identifying small-molecules binding sites in RNA conformational ensembles with SHAMAN
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https://biorxiv.org/cgi/content/short/2023.08.08.552403v1?rss=1"
Panei, F. P.Gkeka, P.Bonomi, M.2023-08-09doi:10.1101/2023.08.08.552403Cold Spring Harbor Laboratory Press2023-08-09
<![CDATA[
Prosaposin maintains adult neural stem cells in a state associated with deep quiescence
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https://biorxiv.org/cgi/content/short/2023.08.08.552453v1?rss=1"
Labusch, M.Thetiot, M.Than-Trong, E.Morizet, D.Coolen, M.Varet, H.Legendre, R.Ortica, S.Mancini, L.Bally-Cuif, L.2023-08-09doi:10.1101/2023.08.08.552453Cold Spring Harbor Laboratory Press2023-08-09
<![CDATA[
Genomic and epidemiological evidence for the emergence of a putative L. donovani/L. infantum hybrid with unusual epidemiology in Northern Italy
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https://biorxiv.org/cgi/content/short/2023.08.09.552585v1?rss=1"
Bruno, F.Castelli, G.Li, B.Reale, S.Carra, E.Vitale, F.Scibetta, S.Calzolari, M.Varani, S.Ortalli, M.Franceschini, E.Gennari, W.Rugna, G.Spaeth, G. F.2023-08-09doi:10.1101/2023.08.09.552585Cold Spring Harbor Laboratory Press2023-08-09
<![CDATA[
Ton Motor Conformational Switch and Peptidoglycan Role in Bacterial Nutrient Uptake
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https://biorxiv.org/cgi/content/short/2023.08.11.552980v1?rss=1"
Zinke, M.Lejeune, M.Mechaly, A.Bardiaux, B.Boneca, I.Delepelaire, P.Izadi-Pruneyre, N.2023-08-13doi:10.1101/2023.08.11.552980Cold Spring Harbor Laboratory Press2023-08-13
<![CDATA[
Spatiotemporal dynamics of cytokines expression dictate fetal liver hematopoiesis.
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https://biorxiv.org/cgi/content/short/2023.08.24.554612v1?rss=1"
Peixoto, M. M.Soares-da-Silva, F.Bonnet, V.Ronteix, G.Santos, R. F.Mailhe, M.-P.Feng, X.Pereira, J.Azzoni, E.Anselmi, G.de Bruijn, M.Baroud, C.Pinto-do-O, P.Cumano, A.2023-08-25doi:10.1101/2023.08.24.554612Cold Spring Harbor Laboratory Press2023-08-25
<![CDATA[
Tuning apico-basal polarity and junctional recycling in the hemogenic endothelium orchestrates pre-hematopoietic stem cell emergence complexity
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https://biorxiv.org/cgi/content/short/2023.09.01.555862v1?rss=1"
TORCQ, L.MAJELLO, S.VIVIER, C.SCHMIDT, A. A.2023-09-03doi:10.1101/2023.09.01.555862Cold Spring Harbor Laboratory Press2023-09-03
<![CDATA[
Predictable sequential structure enhances auditory sensitivity in clinical audiograms
]]>
https://biorxiv.org/cgi/content/short/2023.10.03.560670v1?rss=1"
Marin, N.Gerenton, G.Jean, H.Paraouty, N.Lazard, D. S.Arnal, L. H.Doelling, K. B.2023-10-05doi:10.1101/2023.10.03.560670Cold Spring Harbor Laboratory Press2023-10-05
<![CDATA[
Seminal plasma inhibits Chlamydia trachomatis infection in vitro, and may have consequences on mucosal immunity
]]>
https://biorxiv.org/cgi/content/short/2023.10.10.561648v1?rss=1"
Reot, L.Adapen, C.Cannou, C.Nunez, N.Lakoum, S.Pimienta, C.Lacroix, L.Binois, O.Frydman, N.Nugeyre, M.-T.Le Grand, R.Menu, E.2023-10-11doi:10.1101/2023.10.10.561648Cold Spring Harbor Laboratory Press2023-10-11
<![CDATA[
Cancer-on-a-chip model shows that the adenomatous polyposis coli mutation impairs T cell engagement and killing of cancer spheroids
]]>
https://biorxiv.org/cgi/content/short/2023.10.17.562521v1?rss=1"
Bonnet, V.Maikranz, E.Madec, M.Vertti-Quintero, N.Cuche, C.Mastrogiovanni, M.Alcover, A.Di Bartolo, V.Baroud, C.2023-10-20doi:10.1101/2023.10.17.562521Cold Spring Harbor Laboratory Press2023-10-20
<![CDATA[
Trait selection strategy in multi-trait GWAS: Boosting SNPs discoverability
]]>
https://biorxiv.org/cgi/content/short/2023.10.27.564319v1?rss=1"
Suzuki, Y.Menager, H.Brancotte, B.Vernet, R.Nerin, C.Boetto, C.Auvergne, A.Linhard, C.Torchet, R.Lechat, P.Troubat, L.Cho, M. H.Bouzigon, E.Aschard, H.Julienne, H.2023-10-27doi:10.1101/2023.10.27.564319Cold Spring Harbor Laboratory Press2023-10-27
<![CDATA[
Targeted Metagenomic Databases Provide Improved Analysis of Microbiota Samples
]]>
https://biorxiv.org/cgi/content/short/2023.11.15.567155v1?rss=1"
Baud, A.Kennedy, S. P.2023-11-15doi:10.1101/2023.11.15.567155Cold Spring Harbor Laboratory Press2023-11-15
<![CDATA[
Distinct evolution of SARS-CoV-2 Omicron XBB and BA.2.86 lineages combining increased fitness and antibody evasion
]]>
https://biorxiv.org/cgi/content/short/2023.11.20.567873v1?rss=1"
80% of circulating variants in January 2024. The XBB subvariants carry few but recurrent mutations in the spike, whereas BA.2.86.1 and JN.1 harbor >30 additional changes. These variants replicated in IGROV-1 but no longer in Vero E6 and were not markedly fusogenic. They potently infected nasal epithelial cells, with EG.5.1.3 exhibiting the highest fitness. Antivirals remained active. Neutralizing antibody (NAb) responses from vaccinees and BA.1/BA.2-infected individuals were markedly lower compared to BA.1, without major differences between variants. An XBB breakthrough infection enhanced NAb responses against both XBB and BA.2.86 variants. JN.1 displayed lower affinity to ACE2 and higher immune evasion properties compared to BA.2.86.1. Thus, while distinct, the evolutionary trajectory of these variants combines increased fitness and antibody evasion.
]]>Planas, D.Staropoli, I.Michel, V.Lemoine, F.Donati, F.Prot, M.Porrot, F.Benhassine, F. G.Jeyarajah, B.Brisebarre, A.Dehan, O.Bolland, W.Hubert, M.Buchreiser, J.Vanhoucke, T.Rosenbaum, P.Veyer, D.Pere, H.Lina, B.Assant, S. T.Hocqueloux, L.Prazuck, T.Loriere, E. S.Schwartz, O.2023-11-21doi:10.1101/2023.11.20.567873Cold Spring Harbor Laboratory Press2023-11-21
<![CDATA[
Predicting phage-bacteria interactions at the strain level from genomes
]]>
https://biorxiv.org/cgi/content/short/2023.11.22.567924v1?rss=1"
Gaborieau, B.Vaysset, H.Tesson, F.Charachon, I.Dib, N.Bernier, J.Dequidt, T.Georjon, H.Clermont, O.Hersen, P.Debarbieux, L.Ricard, J.-D.Denamur, E.Bernheim, A.2023-11-22doi:10.1101/2023.11.22.567924Cold Spring Harbor Laboratory Press2023-11-22
<![CDATA[
The unique Legionella longbeachae capsule favors intracellular replication and immune evasion
]]>
https://biorxiv.org/cgi/content/short/2023.11.22.568341v1?rss=1"
Schmidt, S.Mondino, S.Gomez-Valero, L.Escoll, P.Mascarenhas, D. P.Goncalves, A.Rusniok, C.Sachse, M.Moya-Nilges, M.Fontaine, T.Zamboni, D. S.Buchrieser, C.2023-11-22doi:10.1101/2023.11.22.568341Cold Spring Harbor Laboratory Press2023-11-22
<![CDATA[
Cytokinetic abscission requires actin-dependent microtubule severing
]]>
https://biorxiv.org/cgi/content/short/2023.12.11.571051v1?rss=1"
Advedissian, T.Fremont, S.Echard, A.2023-12-11doi:10.1101/2023.12.11.571051Cold Spring Harbor Laboratory Press2023-12-11
<![CDATA[
Evidence for NR2F2/COUP-TFII involvement in human testis development
]]>
https://biorxiv.org/cgi/content/short/2024.01.05.574424v1?rss=1"
Wankanit, S.Zidoune, H.Bignon-Topalovic, J.Schlick, L.Houzelstein, D.Fusee, L.Boukri, A.Nouri, N.McElreavey, K.Bashamboo, A.Elzaiat, M.2024-01-06doi:10.1101/2024.01.05.574424Cold Spring Harbor Laboratory Press2024-01-06
<![CDATA[
A Comprehensive Resource for Exploring Antiphage Defense: DefenseFinder Webservice, Wiki and Databases.
]]>
https://biorxiv.org/cgi/content/short/2024.01.25.577194v1?rss=1"
Tesson, F.Planel, R.Egorov, A. A.Georjon, H.Vaysset, H.Brancotte, B.Neron, B.Mordret, E.Atkinson, G. C.Bernheim, A.Cury, J.2024-01-26doi:10.1101/2024.01.25.577194Cold Spring Harbor Laboratory Press2024-01-26
<![CDATA[
Epigenomics coverage data extraction and aggregation in R with tidyCoverage
]]>
https://biorxiv.org/cgi/content/short/2024.01.27.577537v1?rss=1"
SERIZAY, J.Koszul, R.2024-01-30doi:10.1101/2024.01.27.577537Cold Spring Harbor Laboratory Press2024-01-30
<![CDATA[
Recapitulating memory B cell responses in a Lymphoid Organ-Chip to evaluate mRNA vaccine boosting strategies
]]>
https://biorxiv.org/cgi/content/short/2024.02.02.578553v1?rss=1"
Jeger-Madiot, R.Planas, D.Staropoli, I.Kervevan, J.Mary, H.Collina, C.Fonseca, B. F.Debarnot, H.Robinot, R.Gellenoncourt, S.Schwartz, O.Ewart, L.Bscheider, M.Gobaa, S.Chakrabarti, L. A.2024-02-02doi:10.1101/2024.02.02.578553Cold Spring Harbor Laboratory Press2024-02-02
<![CDATA[
Massive perturbation of sound representations by anesthesia in the auditory brainstem
]]>
https://biorxiv.org/cgi/content/short/2024.02.06.579173v1?rss=1"
Gosselin, E.Bagur, S.Bathellier, B.2024-02-07doi:10.1101/2024.02.06.579173Cold Spring Harbor Laboratory Press2024-02-07
<![CDATA[
A tension-induced morphological transition shapes the avian extra-embryonic territory
]]>
https://biorxiv.org/cgi/content/short/2024.02.08.579502v1?rss=1"
Michaut, A.Chamolly, A.Villedieu, A.Corson, F.Gros, J.2024-02-08doi:10.1101/2024.02.08.579502Cold Spring Harbor Laboratory Press2024-02-08
<![CDATA[
Infection-on-Chip: an in vitro human vessel to study Neisseria meningitidis colonization and vascular damages
]]>
https://biorxiv.org/cgi/content/short/2024.02.09.579276v1?rss=1"
Pinon, L.Chabaud, M.Nivoit, P.Wong-Ng, J.Nguyen, T.-T.Paul, V.Goussard, S.Frachon, E.Obino, D.Gobaa, S.Dumenil, G.2024-02-10doi:10.1101/2024.02.09.579276Cold Spring Harbor Laboratory Press2024-02-10
<![CDATA[
scConfluence : single-cell diagonal integration with regularized Inverse Optimal Transport on weakly connected features
]]>
https://biorxiv.org/cgi/content/short/2024.02.26.582051v1?rss=1"
Samaran, J.Peyre, G.Cantini, L.2024-02-29doi:10.1101/2024.02.26.582051Cold Spring Harbor Laboratory Press2024-02-29
<![CDATA[
Non-apoptotic caspase events and Atf3 expression underlie direct neuronal differentiation of adult neural stem cells
]]>
https://biorxiv.org/cgi/content/short/2024.03.09.584233v1?rss=1"
Rosa, F.Dray, N.Bally-Cuif, L.2024-03-13doi:10.1101/2024.03.09.584233Cold Spring Harbor Laboratory Press2024-03-13
<![CDATA[
Signal-independent activation reveals two-component regulatory networks
]]>
https://biorxiv.org/cgi/content/short/2024.03.22.586261v1?rss=1"
Claverie, C.Coppolino, F.Mazzuoli, M.-V.Guyonnet, C.Jacquemet, E.Legendre, R.Sismeiro, O.De Gaetano, G. V.Teti, G.Trieu-Cuot, P.Tazi, A.Beninati, C.Firon, A.2024-03-24doi:10.1101/2024.03.22.586261Cold Spring Harbor Laboratory Press2024-03-24
<![CDATA[
Deep learning-based detection of murine congenital heart defects from μCT scans
]]>
https://biorxiv.org/cgi/content/short/2024.04.06.588383v1?rss=1"
Nguyen, H.Desgrange, A.Ochandorena-Saa, A.Benhamo, V.Meilhac, S.Zimmer, C.2024-04-10doi:10.1101/2024.04.06.588383Cold Spring Harbor Laboratory Press2024-04-10
<![CDATA[
Large circulation of a novel vesiculovirus in bats in the Mediterranean region
]]>
https://biorxiv.org/cgi/content/short/2024.04.24.590417v1?rss=1"
Luo, D. S.Harazim, M.Maufrais, C.Bonas, S.Martinkova, N.Lalis, A.Nakoune, E.Adjogoua, E. V.Douno, M.Kadjo, B.Lopez-Roig, M.Pikula, J.Shi, Z. L.Bourhy, H.Serra-Cobo, J.Dacheux, L.2024-04-24doi:10.1101/2024.04.24.590417Cold Spring Harbor Laboratory Press2024-04-24
<![CDATA[
Statistical signature of subtle behavioural changes inlarge-scale behavioural assays
]]>
https://biorxiv.org/cgi/content/short/2024.05.03.591825v1?rss=1"
Blanc, A.Laurent, F.Barbier--Chebbah, A.Cocanougher, B. T.Jones, B. M. W.Hague, P.Zlatic, M.Chikhi, R.Vestergaard, C. L.Jovanic, T.Masson, J.-B.Barre, C.2024-05-05doi:10.1101/2024.05.03.591825Cold Spring Harbor Laboratory Press2024-05-05
<![CDATA[
In utero adeno-associated virus (AAV)-mediated gene delivery targeting sensory and supporting cells in the embryonic mouse inner ear
]]>
https://biorxiv.org/cgi/content/short/2024.05.07.592885v1?rss=1"
Barbosa Spinola, C. M.Boutet de Monvel, J.Safieddine, S.Lahlou, G.Etournay, R.2024-05-08doi:10.1101/2024.05.07.592885Cold Spring Harbor Laboratory Press2024-05-08
<![CDATA[
Clostridioides difficile binary toxin CDT induces biofilm-like persisting microcolonies
]]>
https://biorxiv.org/cgi/content/short/2024.05.23.595336v1?rss=1"
Torres, J. M.Tinevez, J.-Y.Crozouls, A.Mary, H.Kim, M.Hunault, L.Chamorro-Rodriguez, S.Lejal, E.Altamirano-Silva, P.Gobaa, S.Peltier, J.Chassaing, B.Dupuy, B.2024-05-23doi:10.1101/2024.05.23.595336Cold Spring Harbor Laboratory Press2024-05-23
<![CDATA[
CHRFAM7A overexpression in human iPSC-derived Interneurons dysregulates α7-nAChR surface expression and alters response to oligomeric β-amyloid peptide
]]>
https://biorxiv.org/cgi/content/short/2024.06.04.597325v1?rss=1"
Llach Pou, M.Thiberge, C.Pons, S.Maskos, U.Cloez-Tayarani, I.2024-06-05doi:10.1101/2024.06.04.597325Cold Spring Harbor Laboratory Press2024-06-05
<![CDATA[
In-host evolution of Yersinia enterocolitica during a chronic human infection
]]>
https://biorxiv.org/cgi/content/short/2024.06.12.598599v1?rss=1"
Savin, C.Le-Bury, P.Guglielmini, J.Douche, T.Buzele, R.Le Brun, C.Bastides, F.Francois, M.Birmele, B.Guichard, L.Cabanel, N.Dortet, L.Matondo, M.Dussurget, O.Carniel, E.Lanotte, P.Pizarro-Cerde, J.2024-06-12doi:10.1101/2024.06.12.598599Cold Spring Harbor Laboratory Press2024-06-12
<![CDATA[
A type IVB secretion system contributes to the pathogenicity of Yersinia pseudotuberculosis strains responsible for the Far East scarlet-like fever
]]>
https://biorxiv.org/cgi/content/short/2024.06.14.598817v1?rss=1"
Lemarignier, M.Savin, C.Ruedas Torres, I.Derbise, A.Coluzzi, C.Burlaud-Gaillard, J.Madej, J.Beau, R.Roingeard, P.Lechat, P.Rocha, E. P.Gomez-Laguna, J.Pizarro-Cerda, J.2024-06-14doi:10.1101/2024.06.14.598817Cold Spring Harbor Laboratory Press2024-06-14
<![CDATA[
Maternal diet alters offspring early life host-microbiota communication through goblet cells, resulting in long-lasting diseases susceptibility
]]>
https://biorxiv.org/cgi/content/short/2024.07.05.602179v1?rss=1"
Delaroque, C.Bonazzi, E.Huillet, M.Ellero-Simatos, S.Hao, F.Patterson, A.Chassaing, B.2024-07-06doi:10.1101/2024.07.05.602179Cold Spring Harbor Laboratory Press2024-07-06
<![CDATA[
Learning cell fate landscapes from spatial transcriptomics using Fused Gromov-Wasserstein
]]>
https://biorxiv.org/cgi/content/short/2024.07.26.605241v1?rss=1"
Huizing, G.-J.Peyre, G.Cantini, L.2024-07-26doi:10.1101/2024.07.26.605241Cold Spring Harbor Laboratory Press2024-07-26
<![CDATA[
scPRINT: pre-training on 50 million cells allows robust gene network predictions
]]>
https://biorxiv.org/cgi/content/short/2024.07.29.605556v1?rss=1"
Kalfon, J.Samaran, J.Peyre, G.Cantini, L.2024-07-29doi:10.1101/2024.07.29.605556Cold Spring Harbor Laboratory Press2024-07-29
<![CDATA[
Adaptive immunity to retroelements promotes barrier integrity
]]>
https://biorxiv.org/cgi/content/short/2024.08.09.606346v1?rss=1"
Wells, A. C.Lima-Junior, D. S.Link, V. M.Smelkinson, M.Krishnamurthy, S. R.Chi, L.Segrist, E.Rivera, C. A.Teijeiro, A.Bouladoux, N.Belkaid, Y.2024-08-09doi:10.1101/2024.08.09.606346Cold Spring Harbor Laboratory Press2024-08-09
<![CDATA[
Assessing the effect of model specification and prior sensitivity on Bayesian tests of temporal signal
]]>
https://biorxiv.org/cgi/content/short/2024.08.12.607579v1?rss=1"
Tay, J. H.Kocher, A.Duchene, S.2024-08-12doi:10.1101/2024.08.12.607579Cold Spring Harbor Laboratory Press2024-08-12
<![CDATA[
Parallel mechanisms signal a hierarchy of sequence structure violations in the auditory cortex
]]>
https://biorxiv.org/cgi/content/short/2024.08.21.609026v1?rss=1"
Jamali, S.Bagur, S.Bremont, E.Van Kerkoerle, T.Dehaene, S.Bathellier, B.2024-08-22doi:10.1101/2024.08.21.609026Cold Spring Harbor Laboratory Press2024-08-22
<![CDATA[
Bacterial growth under confinement requires transcriptional adaptation to resist metabolite-induced turgor pressure build-up
]]>
https://biorxiv.org/cgi/content/short/2024.09.20.614086v1?rss=1"
Le Blanc, L.Alric, B.Rollin, R.Xenard, L.Ramirez Finn, L.Goussard, S.Mazenq, L.Ingersoll, M. A.Piel, M.Tinevez, J.-Y.Delarue, M.Dumenil, G.Bonazzi, D.2024-09-21doi:10.1101/2024.09.20.614086Cold Spring Harbor Laboratory Press2024-09-21
<![CDATA[
Revisiting oxygen toxicity: evolution and adaptation to superoxide in a SOD-deficient bacterial pathogen
]]>
https://biorxiv.org/cgi/content/short/2024.09.25.614947v1?rss=1"
Huete, S. G.Leyva, A.Kornobis, E.Cokelaer, T.Lechat, P.Monot, M.Duran, R.Picardeau, M.BENAROUDJ, N.2024-09-25doi:10.1101/2024.09.25.614947Cold Spring Harbor Laboratory Press2024-09-25
<![CDATA[
Accurate genotyping of three major respiratory bacterial pathogens with ONT R10.4.1 long-read sequencing
]]>
https://biorxiv.org/cgi/content/short/2024.10.03.616467v1?rss=1"
Zidane, N.Rodrigues, C.Bouchez, V.Rethoret-Pasty, M.Passet, V.Brisse, S.Crestani, C.2024-10-03doi:10.1101/2024.10.03.616467Cold Spring Harbor Laboratory Press2024-10-03
<![CDATA[
HIV-1 budding requires cortical actin disassembly by the oxidoreductase MICAL1
]]>
https://biorxiv.org/cgi/content/short/2024.10.07.616958v1?rss=1"
Serrano, T.Casartelli, N.Ghasemi, F.Wioland, H.Cuvelier, F.Salles, A.Moya-Nilges, M.Welker, L.Bernacchi, S.Ruff, M.Jegou, A.Romet-Lemonne, G.Schwartz, O.Fremont, S.Echard, A.2024-10-07doi:10.1101/2024.10.07.616958Cold Spring Harbor Laboratory Press2024-10-07
<![CDATA[
Notch signaling blockade links transcriptome heterogeneity in quiescent neural stem cells with their reactivation routes and potential
]]>
https://biorxiv.org/cgi/content/short/2024.11.01.621547v1?rss=1"
Morizet, D.Foucher, I.Alunni, A.Bally-Cuif, L.2024-11-01doi:10.1101/2024.11.01.621547Cold Spring Harbor Laboratory Press2024-11-01
<![CDATA[
Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal
]]>
https://biorxiv.org/cgi/content/short/2024.11.08.622039v1?rss=1"
Vial, T.Lopez-Maestre, H.Couderc, E.Pinaud, S.Howick, V.Akorli, J.Lawniczak, M.Marti, G.Merkling, S. H.2024-11-11doi:10.1101/2024.11.08.622039Cold Spring Harbor Laboratory Press2024-11-11
<![CDATA[
Adhesion-Controlled Mechanics of the Glial Niche Regulate Neural Stem Cell Proliferative Potential
]]>
https://biorxiv.org/cgi/content/short/2024.12.11.628019v1?rss=1"
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org.highwire.dtl.DTLVardef@18137f8org.highwire.dtl.DTLVardef@819740org.highwire.dtl.DTLVardef@1f0ed0forg.highwire.dtl.DTLVardef@5ba0e4_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>Cristina, A. S.Briand, D.Kukde, A.Perthame, E.Rigaud, S.Tinevez, J.-Y.Banach-Latapy, A.Owens, N. D. L.Valon, L.Bellaiche, Y.Speder, P.2024-12-17doi:10.1101/2024.12.11.628019Cold Spring Harbor Laboratory Press2024-12-17
<![CDATA[
Developmental delay ensures global tissue size robustness upon local induction of apoptosis
]]>
https://biorxiv.org/cgi/content/short/2024.12.21.629882v1?rss=1"
Staneva, R.Sobczyk-Moran, G.Levillayer, F.Villars, A.Davidovic, A.Levayer, R.2024-12-21doi:10.1101/2024.12.21.629882Cold Spring Harbor Laboratory Press2024-12-21
<![CDATA[
A simple ex vivo bladder infection model permits study of host-pathogen interactions in UTI
]]>
https://biorxiv.org/cgi/content/short/2024.12.23.630047v1?rss=1"
Koehn, R.-M.Durand, M.Ramirez Finn, L.Costas, A.Soderstrom, B.Lacerda Mariano, L.Ingersoll, M. A.2024-12-23doi:10.1101/2024.12.23.630047Cold Spring Harbor Laboratory Press2024-12-23
<![CDATA[
Interfacial tension and growth both contribute to mechanical cell competition
]]>
https://biorxiv.org/cgi/content/short/2025.01.09.632135v1?rss=1"
Valon, L.Matamoro-Vidal, A.Villars, A.Levayer, R.2025-01-13doi:10.1101/2025.01.09.632135Cold Spring Harbor Laboratory Press2025-01-13
<![CDATA[
A novel approach to tagging tubulin reveals microtubule assembly dynamics of the axoneme in Trypanosoma brucei
]]>
https://biorxiv.org/cgi/content/short/2025.01.27.634986v1?rss=1"
Abbuhl, D.Pruzincova, M.Stepanek, L.Bouscasse, E.Azevedo, R.Matondo, M.Varga, V.BONNEFOY, S.BASTIN, P.2025-01-27doi:10.1101/2025.01.27.634986Cold Spring Harbor Laboratory Press2025-01-27
<![CDATA[
Fine-tuning mechanical constraints uncouple patterning and gene expression in murine pseudo-embryos
]]>
https://biorxiv.org/cgi/content/short/2025.01.28.635012v1?rss=1"
Pineau, J.Ng, J. W.Mayran, A.Lopez-Delisle, L.Osteil, P.Shoushtarizadeh, A.Duboule, D.Gobaa, S.Gregor, T.2025-01-29doi:10.1101/2025.01.28.635012Cold Spring Harbor Laboratory Press2025-01-29
<![CDATA[
Mass spectrometry reveals novel features of tubulin polyglutamylation in the flagellum of Trypanosoma brucei
]]>
https://biorxiv.org/cgi/content/short/2025.02.06.636787v1?rss=1"
Nisavic, M.Chaze, T.BONNEFOY, S.Janke, C.Bastin, P.Matondo, M.Chamot-Rooke, J.2025-02-06doi:10.1101/2025.02.06.636787Cold Spring Harbor Laboratory Press2025-02-06
<![CDATA[
Abdominal symptoms of invasive meningococcal disease are associated with the induction of plasminogen activator inhibitor in omental adipocytes
]]>
https://biorxiv.org/cgi/content/short/2025.02.26.640293v1?rss=1"
Taha, M.-K.Oliveira, D.Gros, M.Aouiti-Trabelsi, M.Deghmane, A.-E.2025-02-26doi:10.1101/2025.02.26.640293Cold Spring Harbor Laboratory Press2025-02-26
<![CDATA[
Persistent viral infections impact key biological traits in Drosophila melanogaster
]]>
https://biorxiv.org/cgi/content/short/2025.03.12.642769v1?rss=1"
Castello-Sanjuan, M.Gonzalez, R.Romoli, O.Blanc, H.Nigg, J.Saleh, M.-C.2025-03-12doi:10.1101/2025.03.12.642769Cold Spring Harbor Laboratory Press2025-03-12
<![CDATA[
Viral infections reduce Drosophila lifespan through accelerated aging
]]>
https://biorxiv.org/cgi/content/short/2025.03.13.643076v1?rss=1"
Gonzalez, R.Castello-Sanjuan, M.Saleh, M.-C.2025-03-13doi:10.1101/2025.03.13.643076Cold Spring Harbor Laboratory Press2025-03-13
<![CDATA[
Interplay between T3SS effectors, ExoY activation, and cGMP signaling in Pseudomonas aeruginosa infection
]]>
https://biorxiv.org/cgi/content/short/2025.03.26.645418v1?rss=1"
Deruelle, V.Dupuis, G.Raoux-Barbot, D.Lim, E.Ponce-Lopez, R.Ladant, D.Renault, L.Mechold, U.2025-03-26doi:10.1101/2025.03.26.645418Cold Spring Harbor Laboratory Press2025-03-26
<![CDATA[
Structural Basis for DNA Replication and Uracil Repair in Phage A-Family DNA Polymerases
]]>
https://biorxiv.org/cgi/content/short/2025.03.26.645540v1?rss=1"
Missoury, S.Lucas-Staat, S.Sieskind, R.Delarue, M. H.2025-03-26doi:10.1101/2025.03.26.645540Cold Spring Harbor Laboratory Press2025-03-26
<![CDATA[
Oral OM-89 in combination with antibiotics prevents recurrent infection in a mouse model of urinary tract infection
]]>
https://biorxiv.org/cgi/content/short/2025.04.04.647233v1?rss=1"
Canton, T.Durand, M.Baulier, E.Pasquali, C.Calin, R.Ingersoll, M. A.Rousseau, M.2025-04-10doi:10.1101/2025.04.04.647233Cold Spring Harbor Laboratory Press2025-04-10
<![CDATA[
Characterization and evolutionary history of novel SARS-CoV-2-related viruses in bats from Cambodia
]]>
https://biorxiv.org/cgi/content/short/2025.04.15.648942v1?rss=1"
Ou, T. P.Guillebaud, J.Baidaliuk, A.Tum, S.Chheang, D.Delaune, D.Prot, M.Rahal Guaragna Machado, R.Pum, L.Hul, V.Hoem, T.Ly, S.Auerswald, H.Smith, G. J.Dussart, P.Karlsson, E. A.Chevalier, V.Cappelle, J.Duong, V.Simon-Loriere, E.2025-04-16doi:10.1101/2025.04.15.648942Cold Spring Harbor Laboratory Press2025-04-16
<![CDATA[
Feature-dependent decorrelation of sound representations across the auditory pathway
]]>
https://biorxiv.org/cgi/content/short/2025.04.17.649364v1?rss=1"
Gosselin, E.Bagur, S.Jamali, S.Puel, J.-L.Bourien, J.Bathellier, B.2025-04-21doi:10.1101/2025.04.17.649364Cold Spring Harbor Laboratory Press2025-04-21
<![CDATA[
High-quality metagenome assembly from nanopore reads with nanoMDBG
]]>
https://biorxiv.org/cgi/content/short/2025.04.22.649928v1?rss=1"
Benoit, G.James, R.Raguideau, S.Alabone, G.Goodall, T.Chikhi, R.Quince, C.2025-04-24doi:10.1101/2025.04.22.649928Cold Spring Harbor Laboratory Press2025-04-24
<![CDATA[
Plasma protein biomarkers for the early detection of gastric preneoplasia and cancer: a prospective study
]]>
https://biorxiv.org/cgi/content/short/2025.04.29.651246v1?rss=1"
Gianetto, Q. G.Michel, V.Douche, T.Nozeret, K.Zaanan, A.Colussi, O.Trouilloud, I.Pernot, S.Ungeheuer, M.-N.Julie, C.Jolly, N.Taieb, J.Lamarque, D.Matondo, M.Touati, E.2025-04-30doi:10.1101/2025.04.29.651246Cold Spring Harbor Laboratory Press2025-04-30
<![CDATA[
Stealth replication of SARS-CoV-2 Omicron in the nasal epithelium at physiological temperature
]]>
https://biorxiv.org/cgi/content/short/2025.05.03.652024v1?rss=1"
Fonseca, B. F.Robinot, R.Michel, V.Mendez, A.Lebourgeois, S.Chive, C.Jeger-Madiot, R.Vaid, R.Bondet, V.Maloney, E.Guivel-Benhassine, F.Schwartz, O.Duffy, D.Mondal, T.Gobaa, S.Chakrabarti, L. A.2025-05-05doi:10.1101/2025.05.03.652024Cold Spring Harbor Laboratory Press2025-05-05
<![CDATA[
Molecular determinants of species-specific cell-cell recognition activating the class II gamete fusogen HAP2
]]>
https://biorxiv.org/cgi/content/short/2025.05.09.653094v1?rss=1"
Pinello, J. F.Ferrino, A.Hussain, H.Legrand, P.Manikumar, S.Demissie, R.Rey, F. A.Snell, W. J.Baquero, E.2025-05-13doi:10.1101/2025.05.09.653094Cold Spring Harbor Laboratory Press2025-05-13
<![CDATA[
Medial olivocochlear efferent modulation of cochlear micromechanics requires P2X4 expression in outer hair cells
]]>
https://biorxiv.org/cgi/content/short/2025.05.15.654229v1?rss=1"
Riffaut, C.Condamine, S.Bouleau, Y.Boue-Grabot, E.Dulon, D.2025-05-19doi:10.1101/2025.05.15.654229Cold Spring Harbor Laboratory Press2025-05-19
<![CDATA[
Integration of past caspase activity biases cell elimination in vivo
]]>
https://biorxiv.org/cgi/content/short/2025.05.18.654727v1?rss=1"
Cumming, T.Villars, A.Davidovic, A.Levillayer, F.Valon, L.Levayer, R.2025-05-20doi:10.1101/2025.05.18.654727Cold Spring Harbor Laboratory Press2025-05-20
<![CDATA[
Sound offset responses become highly informative in the auditory cortex
]]>
https://biorxiv.org/cgi/content/short/2025.05.19.654889v1?rss=1"
Lamothe, C.Bagur, S.Gosselin, E.Bathellier, B.2025-05-21doi:10.1101/2025.05.19.654889Cold Spring Harbor Laboratory Press2025-05-21
<![CDATA[
Unraveling the prevalence and multifaceted roles of accessory peptide deformylases in bacterial adaptation and resistance
]]>
https://biorxiv.org/cgi/content/short/2025.06.06.657839v1?rss=1"
Lamberioux, M.Ducos-Galand, M.Kaminski, P.-A.Littner, E.Betton, J.-M.Mechaly, A.Haouz, A.Mazel, D.2025-06-06doi:10.1101/2025.06.06.657839Cold Spring Harbor Laboratory Press2025-06-06
<![CDATA[
Atomic resolution ensembles of intrinsically disordered and multi-domain proteins with Alphafold
]]>
https://biorxiv.org/cgi/content/short/2025.06.18.660298v1?rss=1"
Schnapka, V.Morozova, T.Sen, S.Bonomi, M.2025-06-21doi:10.1101/2025.06.18.660298Cold Spring Harbor Laboratory Press2025-06-21
<![CDATA[
Advancing in silico drug design with Bayesian refinement of AlphaFold models
]]>
https://biorxiv.org/cgi/content/short/2025.06.25.661454v1?rss=1"
Sen, S.Hoff, S. E.Morozova, T. I.Schnapka, V.Bonomi, M.2025-06-27doi:10.1101/2025.06.25.661454Cold Spring Harbor Laboratory Press2025-06-27
<![CDATA[
T-bet expressing Tr1 cells driven by dietary signals dominate the small intestinal immune landscape
]]>
https://biorxiv.org/cgi/content/short/2025.06.30.662190v1?rss=1"
Ansaldo, E.Yong, D.Carrillo, N.McFadden, T.Abid, M.Corral, D.Farley, T.Bouladoux, N.Gribonika, I.Belkaid, Y.2025-07-04doi:10.1101/2025.06.30.662190Cold Spring Harbor Laboratory Press2025-07-04
<![CDATA[
Paratyphoid Fever and Relapsing Fever in 1812 Napoleon's Devastated Army
]]>
https://biorxiv.org/cgi/content/short/2025.07.12.664512v1?rss=1"
Barbieri, R.Fumey, J.Kabral, H.Scheib, C. L.Signoli, M.Costedoat, C.Rascovan, N.2025-07-16doi:10.1101/2025.07.12.664512Cold Spring Harbor Laboratory Press2025-07-16
<![CDATA[
Exploring the multi-protein assembly of the enzymes of the de novo purine nucleotide biosynthetic pathway from Pseudomonas aeruginosa
]]>
https://biorxiv.org/cgi/content/short/2025.07.15.664858v1?rss=1"
Ayoub, N.Pietrancosta, N.Giai Gianetto, Q.Karimova, G.Gedeon, A.Munier-Lehmann, H.2025-07-15doi:10.1101/2025.07.15.664858Cold Spring Harbor Laboratory Press2025-07-15
<![CDATA[
Spatiotemporal analysis of sporozoite maturation and infectivity
]]>
https://biorxiv.org/cgi/content/short/2025.07.21.665974v1?rss=1"
Thiberge, J.-M.Verzier, L. H.Aliprandini, E.Lagal, V.Formaglio, P.Silvie, O.Amino, R.2025-07-21doi:10.1101/2025.07.21.665974Cold Spring Harbor Laboratory Press2025-07-21
<![CDATA[
In vivo risk assessment of yellow fever virus transmission through breastfeeding, and mechanistic insights
]]>
https://biorxiv.org/cgi/content/short/2025.07.23.666308v1?rss=1"
Pascard, J.Desgraupes, S.Chiche, A.Jeannin, P.Kanaan, R.Gessain, A.Li, H.CECCALDI, P.-E.Vidy, A.2025-07-23doi:10.1101/2025.07.23.666308Cold Spring Harbor Laboratory Press2025-07-23
<![CDATA[
Jagged-mediated lateral induction patterns Notch3 signaling within adult neural stem cell populations
]]>
https://biorxiv.org/cgi/content/short/2025.07.29.667421v1?rss=1"
ORTICA, S.MARTINEZ-HERRERA, M.DEGROUX, L.ROCHETTE, B.DRAY, N.BALLY-CUIF, L.2025-08-01doi:10.1101/2025.07.29.667421Cold Spring Harbor Laboratory Press2025-08-01
<![CDATA[
InSillyClo, a user-friendly web application to assist large-scale Golden Gate Cloning and MoClo workflows
]]>
https://biorxiv.org/cgi/content/short/2025.07.31.667881v1?rss=1"
Galez, H.Brancotte, B.Bonche, J.Fumey, J.Napolitano, S.Batt, G.2025-07-31doi:10.1101/2025.07.31.667881Cold Spring Harbor Laboratory Press2025-07-31
<![CDATA[
Cell competition overcomes host tissue resistance to unleash tumour growth in a Drosophila brain cancer model
]]>
https://biorxiv.org/cgi/content/short/2025.08.05.668787v1?rss=1"
Gualtieri, M.Jabre, S.Mornico, D.Hamon, M.Maurange, C.Speder, P.2025-08-06doi:10.1101/2025.08.05.668787Cold Spring Harbor Laboratory Press2025-08-06
<![CDATA[
Enhanced detection of low-expressed miRNAs in Leishmania-infected macrophages through RNA fractionation and RT-qPCR optimization
]]>
https://biorxiv.org/cgi/content/short/2025.08.20.671241v1?rss=1"
Maestrini, S.Lecoeur, H.Gharsallah, C.Diotallevi, A.Späth, G. F.Galluzzi, L.Prina, E.2025-08-21doi:10.1101/2025.08.20.671241Cold Spring Harbor Laboratory Press2025-08-21
<![CDATA[
Architecture of a peptidoglycan peptidase complex involved in morphological transition in Helicobacter pylori.
]]>
https://biorxiv.org/cgi/content/short/2025.08.29.672660v1?rss=1"
Danot, O.Mechaly, A.Rifflet, A.Bonis, M.Cheng, T.Haouz, A.Gomperts Boneca, I.2025-08-29doi:10.1101/2025.08.29.672660Cold Spring Harbor Laboratory Press2025-08-29
<![CDATA[
FishFeats: streamlined quantification of multimodal labeling at the single-cell level in 3D tissues
]]>
https://biorxiv.org/cgi/content/short/2025.09.02.673708v1?rss=1"
Letort, G.Foley, T.Mignerey, I.Bally-Cuif, L.Dray, N.2025-09-04doi:10.1101/2025.09.02.673708Cold Spring Harbor Laboratory Press2025-09-04
<![CDATA[
VANGL2 shapes the mouse heart tube from adjacent epithelia and without planar polarity
]]>
https://biorxiv.org/cgi/content/short/2025.09.05.674213v1?rss=1"
Palmquist-Gomes, P.Letort, G.Hegde, A. U.Perez-Pomares, J. M.Meilhac, S. M.2025-09-05doi:10.1101/2025.09.05.674213Cold Spring Harbor Laboratory Press2025-09-05
<![CDATA[
Endogenous retroelements promote tolerance to dietary antigens
]]>
https://biorxiv.org/cgi/content/short/2025.09.09.675192v1?rss=1"
Rivera, C. A.Ansaldo, E.Link, V. M.Krishnamurthy, S. R.Teijeiro, A.Oguz, C.Yong, D.Belkaid, Y.2025-09-09doi:10.1101/2025.09.09.675192Cold Spring Harbor Laboratory Press2025-09-09
<![CDATA[
RABV L protein plays a role in immune escape through its methyltransferase activity
]]>
https://biorxiv.org/cgi/content/short/2025.09.12.675814v1?rss=1"
CASTET, M.AOUADI, w.Kergoat, L.Bulteau, A.Legendre, R.Ouazahrou, R.Feige, L.Varet, H.Attina, A.Hirtz, C.David, A.Decroly, E.Bourhy, H.Larrous, F.2025-09-12doi:10.1101/2025.09.12.675814Cold Spring Harbor Laboratory Press2025-09-12
<![CDATA[
CIRCE: a scalable Python package to predict cis-regulatory DNA interactions from single-cell chromatin accessibility data
]]>
https://biorxiv.org/cgi/content/short/2025.09.23.678054v1?rss=1"
Trimbour, R.Saez-Rodriguez, J.Cantini, L.2025-09-25doi:10.1101/2025.09.23.678054Cold Spring Harbor Laboratory Press2025-09-25
<![CDATA[
Alice: fast and haplotype-aware assembly of high-fidelity reads based on MSR sketching
]]>
https://biorxiv.org/cgi/content/short/2025.09.29.679204v1?rss=1"
Faure, R.Hilaire, B.Flot, J.-F.Lavenier, D.2025-09-30doi:10.1101/2025.09.29.679204Cold Spring Harbor Laboratory Press2025-09-30
<![CDATA[
The E. coli CNF1 toxin induces fetal reprogramming of intestinal stem cells and a serrated colorectal cancer transcriptional signature in organoids
]]>
https://biorxiv.org/cgi/content/short/2025.10.02.680056v1?rss=1"
Letourneur, D.Bergsten, E.Raynaud, N.Mondy, J.Nigro, G.Tsoumtsa Meda, L. L.Vaysse, A.Descorps-Declere, S.Yoshida, A.Stefani, C.Sobhani, I.Lemichez, E.Mettouchi, A.2025-10-04doi:10.1101/2025.10.02.680056Cold Spring Harbor Laboratory Press2025-10-04
<![CDATA[
A modified oncolytic measles virus exhibits strong immunotherapeutic potential through RIG-I activation by defective viral genomes
]]>
https://biorxiv.org/cgi/content/short/2025.10.03.680227v1?rss=1"
Barinov, A.Vera-Peralta, H.Nader, J. S.Najburg, V.Combredet, C.Arbabian, A.Gracias, S.Frantz, P. N.Vibert, R.Simard, E.Coateval, M.Pouliquen, D.Petithomme, T.Prot, M.Simon-Loriere, E.Hardy, D.Louzili, S.Brzezicha, B.Hoffmann, J.Riebbels, V.Le Bigot, J.-F.Gregoire, M.Fonteneau, J.-F.Komarova, A.Boisgerault, N.Tangy, F.2025-10-08doi:10.1101/2025.10.03.680227Cold Spring Harbor Laboratory Press2025-10-08
<![CDATA[
Multi-modal data integration for machine learning applications
]]>
https://biorxiv.org/cgi/content/short/2025.10.10.681692v1?rss=1"
SERIZAY, J.Koszul, R.2025-10-13doi:10.1101/2025.10.10.681692Cold Spring Harbor Laboratory Press2025-10-13
<![CDATA[
The tRNA epitranscriptomic landscape and RNA modification enzymes in Vibrio cholerae
]]>
https://biorxiv.org/cgi/content/short/2025.10.15.682536v1?rss=1"
Hardy, L.Marchand, V.Bourguignon, V.Thuillier, Q.Cathy, D.Krin, E.Fruchard, L.Bar Yaacov, D.Mazel, D.Motorin, Y.Baharoglu, Z.2025-10-16doi:10.1101/2025.10.15.682536Cold Spring Harbor Laboratory Press2025-10-16
<![CDATA[
Microbiome composition modulates the lethal outcome of Drosophila A virus infection
]]>
https://biorxiv.org/cgi/content/short/2025.10.16.682821v1?rss=1"
Gonzalez, R.Castello-Sanjuan, M.Romoli, O.Blanc, H.Kobayashi, H.Nigg, J.Saleh, M.-C.2025-10-16doi:10.1101/2025.10.16.682821Cold Spring Harbor Laboratory Press2025-10-16
<![CDATA[
Influenza Interaction with Cocirculating Pathogens, and Its Impact on Surveillance, Pathogenesis and Epidemic Profile: A Key Role for Mathematical Modeling
]]>
https://biorxiv.org/cgi/content/short/203265v1?rss=1"
Opatowski, L.Baguelin, M.Eggo, R.2017-10-19doi:10.1101/203265Cold Spring Harbor Laboratory Press2017-10-19
<![CDATA[
Comparative genomics and phylogeny unveil lineage diversification of Citrobacter rodentium polyvalent bacteriophage
]]>
https://biorxiv.org/cgi/content/short/248153v1?rss=1"
Mizuno, C. M.Debarbieux, L.Roach, D. R.2018-01-15doi:10.1101/248153Cold Spring Harbor Laboratory Press2018-01-15
<![CDATA[
Parallels between experimental and natural evolution of legume symbionts
]]>
https://biorxiv.org/cgi/content/short/250159v1?rss=1"
Clerissi, C.Touchon, M.Capela, D.Tang, M.Cruveiller, S.Parker, M. A.Moulin, L.Masson-Boivin, C.Rocha, E. P. C.2018-01-18doi:10.1101/250159Cold Spring Harbor Laboratory Press2018-01-18
<![CDATA[
RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection
]]>
https://biorxiv.org/cgi/content/short/265462v1?rss=1"
Ates, L. S.Sayes, F.Frigui, W.Ummels, R.Damen, M. P. M.Bottai, D.Behr, M. A.Bitter, W.Majlessi, L.Brosch, R.2018-02-14doi:10.1101/265462Cold Spring Harbor Laboratory Press2018-02-14
<![CDATA[
Control of flagellum length by a grow-and-lock model
]]>
https://biorxiv.org/cgi/content/short/266759v1?rss=1"
Bertiaux, E.Morga, B.Blisnick, T.Rotureau, B.Bastin, P.2018-02-16doi:10.1101/266759Cold Spring Harbor Laboratory Press2018-02-16
<![CDATA[
Detection and Degradation of Nonsense-mediated mRNA Decay Substrates Involve Two Distinct Upf1-bound Complexes
]]>
https://biorxiv.org/cgi/content/short/266833v1?rss=1"
Dehecq, M.Decourty, L.Namane, A.Proux, C.Kanaan, J.Le Hir, H.Jacquier, A.Saveanu, C.2018-02-16doi:10.1101/266833Cold Spring Harbor Laboratory Press2018-02-16
<![CDATA[
Compound signaling activates endogenous retroviruses by inducing enhancer and gene-neighborhood transcription
]]>
https://biorxiv.org/cgi/content/short/284695v1?rss=1"
Azebi, S.Batsche, E.Michel, F.Kornobis, E.Muchardt, C.2018-03-19doi:10.1101/284695Cold Spring Harbor Laboratory Press2018-03-19
<![CDATA[
Inference of significant microbial interactions from longitudinal metagenomics sequencing data
]]>
https://biorxiv.org/cgi/content/short/305326v1?rss=1"
Gao, X.Huynh, B.-T.Guillemot, D.Glaser, P.Opatowski, L.2018-04-20doi:10.1101/305326Cold Spring Harbor Laboratory Press2018-04-20
<![CDATA[
Mapping of TNTs using Correlative Cryo-Electron Microscopy Reveals a Novel Structure
]]>
https://biorxiv.org/cgi/content/short/342469v1?rss=1"
Sartori-Rupp, A.Cordero Cervantes, D.Pepe, A.Delage, E.Gousset, K.Corroyer-Dulmont, S.Schmitt, C.Krijnse-Locker, J.Zurzolo, C.2018-06-08doi:10.1101/342469Cold Spring Harbor Laboratory Press2018-06-08
<![CDATA[
Live Mouse Tracker: real-time behavioral analysis of groups of mice
]]>
https://biorxiv.org/cgi/content/short/345132v1?rss=1"
de Chaumont, F.Ey, E.Torquet, N.Lagache, T.Dallongeville, S.Imbert, A.Legou, T.Le Sourd, A.-M.Faure, P.Bourgeron, T.Olivo-Marin, J.-C.2018-06-14doi:10.1101/345132Cold Spring Harbor Laboratory Press2018-06-14
<![CDATA[
More than 16,000 effectors in the Legionella genus genome provide multiple, independent combinations for replication in human cells
]]>
https://biorxiv.org/cgi/content/short/350777v1?rss=1"
16,000) containing eukaryotic-like proteins acquired from all domains of life (plant, animal, fungal, archaea) is contrasting with a highly conserved type 4 secretion system. This study reveals an unprecedented environmental reservoir of bacterial virulence factors, and provides a new understanding of how reshuffling and gene-acquisition from environmental eukaryotic hosts, may allow for the emergence of human pathogens.nnAbstractThe bacterial genus Legionella comprises 65 species among, which Legionella pneumophila is a human pathogen causing severe pneumonia. To understand the evolution of an environmental to an accidental human pathogen, we have functionally analyzed 80 Legionella genomes spanning 58 species. Uniquely, an immense repository of 16,000 secreted proteins encoding 137 different eukaryotic-like domains and more than 200 eukaryotic-like proteins is paired with a highly conserved T4SS. Specifically, we show that eukaryotic Rho and Rab GTPase domains are found nearly exclusively in eukaryotes and Legionella species. Translocation assays for selected Rab-GTPase proteins revealed that they are indeed T4SS secreted substrates. Furthermore, F/U-box and SET domains were present in >70% of all species suggesting that manipulation of host signal transduction, protein turnover and chromatin modification pathways, respectively are fundamental intracellular replication strategies for Legionellae. In contrast, the Sec-7 domain was restricted to L. pneumophila and seven other species, indicating effector repertoire tailoring within different amoebae. Functional screening of 47 species revealed 60% were competent for intracellular replication in THP-1 cells, but interestingly this phenotype was associated with diverse effector assemblages. These data, combined with evolutionary analysis indicate that the capacity to infect eukaryotic cells has been acquired independently many times within the genus and that a highly conserved yet versatile T4SS secretes an exceptional number of different proteins shaped by inter-domain gene transfer. Furthermore we revealed the surprising extent to which legionellae have co-opted genes and thus cellular functions from their eukaryotic hosts and provides a new understanding of how dynamic reshuffling and gene-acquisition has led to the emergence of major human pathogens.
]]>Gomez-Valero, L.Rusniok, C.Carson, D.Mondino, S.Perez-Cobas, A. E.Rolando, M.Pasricha, S.Reuter, S.Demirtas, J.Crumbach, J.Descorps-Declere, S.Hartland, E. L.Jarraud, S.Dougan, G.Schroeder, G. N.Frankel, G.Buchrieser, C.2018-06-19doi:10.1101/350777Cold Spring Harbor Laboratory Press2018-06-19
<![CDATA[
Distribution and asymptotic behavior of the phylogenetic transfer distance
]]>
https://biorxiv.org/cgi/content/short/368993v1?rss=1"
Davila Felipe, M.Domelevo Entfellner, J.-B.Lemoine, F.Truszkowski, J.Gascuel, O.2018-07-13doi:10.1101/368993Cold Spring Harbor Laboratory Press2018-07-13
<![CDATA[
Exploring the Genetic Basis of Human Population Differences in DNA Methylation and their Causal Impact on Immune Gene Regulation
]]>
https://biorxiv.org/cgi/content/short/371872v1?rss=1"
Husquin, L. T.Rotival, M.Fagny, M.Quach, H.Zidane, N.McEwen, L. M.MacIsaac, J. L.Kobor, M. S.Aschard, H.Patin, E.Quintana-Murci, L.2018-07-23doi:10.1101/371872Cold Spring Harbor Laboratory Press2018-07-23
<![CDATA[
Rethinking the efficacy of acellular pertussis vaccines for primary immunization
]]>
https://biorxiv.org/cgi/content/short/376947v1?rss=1"
Domenech de Celles, M.Rohani, P.King, A. A.2018-07-25doi:10.1101/376947Cold Spring Harbor Laboratory Press2018-07-25
<![CDATA[
A Fast Likelihood Method to Reconstruct and Visualize Ancestral Scenarios
]]>
https://biorxiv.org/cgi/content/short/379529v1?rss=1"
Ishikawa, S.Zhukova, A.Iwasaki, W.Gascuel, O.2018-07-29doi:10.1101/379529Cold Spring Harbor Laboratory Press2018-07-29
<![CDATA[
Unique morphogenetic signatures define mammalian neck muscles and associated connective tissues
]]>
https://biorxiv.org/cgi/content/short/380774v1?rss=1"
Heude, E.Tesarova, M.Sefton, E. M.Jullian, E.Adachi, N.Grimaldi, A.Zikmund, T.Kaiser, J.Kardon, G.Kelly, R.Tajbakhsh, S.2018-08-03doi:10.1101/380774Cold Spring Harbor Laboratory Press2018-08-03
<![CDATA[
Transcription factor activity and nucleosome organisation in mitosis
]]>
https://biorxiv.org/cgi/content/short/392241v1?rss=1"
Festuccia, N.Owens, N.Papadopoulou, T.Gonzalez, I.Tachtsidi, A.Vandoermel-Pournin, S.Gallego, E.Gutierrez, N.Dubois, A.Cohen-Tannoudji, M.Navarro, P.2018-08-15doi:10.1101/392241Cold Spring Harbor Laboratory Press2018-08-15
<![CDATA[
Studying 3D cell cultures in a microfluidic droplet array under multiple time-resolved conditions
]]>
https://biorxiv.org/cgi/content/short/407759v1?rss=1"
Tomasi, R.Sart, S.Champetier, T.Baroud, C.2018-09-04doi:10.1101/407759Cold Spring Harbor Laboratory Press2018-09-04
<![CDATA[
A SKI subcomplex specifically required for the degradation of ribosome-free RNA regions
]]>
https://biorxiv.org/cgi/content/short/409490v1?rss=1"
Fromont-Racine, M.Zhang, E.Khanna, V.Namane, A.Doyen, A.Dacheux, E.Turcotte, B.Jacquier, A.2018-09-05doi:10.1101/409490Cold Spring Harbor Laboratory Press2018-09-05
<![CDATA[
Close proximity interactions support transmission of ESBL-K. pneumoniae but not ESBL-E. coli in healthcare settings
]]>
https://biorxiv.org/cgi/content/short/413500v1?rss=1"
Duval, A.Obadia, T.Boëlle, P.-Y.Fleury, E.Herrmann, J.-L.Guillemot, D.Temime, L.Opatowski, L.i-Bird Study group,2018-09-10doi:10.1101/413500Cold Spring Harbor Laboratory Press2018-09-10
<![CDATA[
Distinct nanoscale calcium channel and synaptic vesicle topographies contribute to the diversity of synaptic function
]]>
https://biorxiv.org/cgi/content/short/421370v1?rss=1"
Rebola, N.Reva, M.Kirizs, T.Szoboszlay, M.Moneron, G.Nusser, Z.DiGregorio, D.2018-09-20doi:10.1101/421370Cold Spring Harbor Laboratory Press2018-09-20
<![CDATA[
Microtubule acetylation but not detyrosination promotes focal adhesion dynamics and cell migration
]]>
https://biorxiv.org/cgi/content/short/425421v1?rss=1"
Bance, B.Seetharaman, S.Leduc, C.Boeda, B.Etienne-Manneville, S.2018-09-24doi:10.1101/425421Cold Spring Harbor Laboratory Press2018-09-24
<![CDATA[
Imaging of red-shifted photons from bioluminescent tumours using fluorescence by unbound excitation from luminescence
]]>
https://biorxiv.org/cgi/content/short/428771v1?rss=1"
Sonego, F.Bouccara, S.Pons, T.Lequeux, N.Danckaert, A.Tinevez, J.-Y.Alam, I.Shorte, S. L.Tournebize, R.2018-09-27doi:10.1101/428771Cold Spring Harbor Laboratory Press2018-09-27
<![CDATA[
Stepwise evolution and convergent recombination underlie the global dissemination of carbapenemase-producing Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/446195v1?rss=1"
Patino-Navarrete, R.Rosinski-Chupin, I.Cabanel, N.Gauthier, L.Takissian, J.Madec, J.-Y.Hamze, M.Bonnin, R. A.Naas, T.Glaser, P.2018-10-17doi:10.1101/446195Cold Spring Harbor Laboratory Press2018-10-17
<![CDATA[
A comprehensive study of metabolite genetics reveals strong pleiotropy and heterogeneity across time and context
]]>
https://biorxiv.org/cgi/content/short/461848v1?rss=1"
Gallois, A.Mefford, J.Ko, A.Vaysse, A.Laakso, M.Zaitlen, N.Pajukanta, P.Aschard, H.2018-11-12doi:10.1101/461848Cold Spring Harbor Laboratory Press2018-11-12
<![CDATA[
De novo profiling of RNA viruses in Anopheles malaria vector mosquitoes from forest ecological zones in Senegal and Cambodia
]]>
https://biorxiv.org/cgi/content/short/464719v1?rss=1"
500 nucleotides strongly matched a pattern of classic RNAi processing of viral replication intermediates, and 1566 unclassified contigs strongly matched a pattern consistent with piRNAs. Analysis of piRNA expression in Anopheles coluzzii after infection with Onyong nyong virus (family Togaviridae) suggests that virus infection can specifically alter abundance of some piRNAs.nnConclusionsRNA viruses ubiquitously colonize Anopheles vectors of human malaria worldwide. At least some members of the mosquito virome are monophyletic with other arthropod viruses. However, high levels of collinearity and similarity of Anopheles viruses at the peptide level is not necessarily matched by similarity at the nucleotide level, indicating that Anopheles from Africa and Asia are colonized by closely related but clearly diverged virome members. The interplay between small RNA pathways and the virome may represent an important part of the homeostatic mechanism maintaining virome members in a commensal or nonpathogenic state, and host-virome interactions could influence variation in malaria vector competence.
]]>Belda, E.Nanfack Minkeu, F.Eiglmeier, K.Carissimo, G.Holm, I.Diallo, M.Diallo, D.Vantaux, A.Kim, S.Sharakhov, I. V.Vernick, K. D.2018-11-07doi:10.1101/464719Cold Spring Harbor Laboratory Press2018-11-07
<![CDATA[
IFT25 is required for the construction of the trypanosome flagellum
]]>
https://biorxiv.org/cgi/content/short/479642v1?rss=1"
Huet, D.Blisnick, T.Perrot, S.Bastin, P.2018-11-26doi:10.1101/479642Cold Spring Harbor Laboratory Press2018-11-26
<![CDATA[
A Darwinian Uncertainty Principle
]]>
https://biorxiv.org/cgi/content/short/506535v1?rss=1"
Gascuel, O.Steel, M.2018-12-26doi:10.1101/506535Cold Spring Harbor Laboratory Press2018-12-26
<![CDATA[
Mapping Structure and Biological Functions within Mesenchymal Bodies using Microfluidics
]]>
https://biorxiv.org/cgi/content/short/514158v1?rss=1"
Sart, S.Tomasi, R. F. X.Barizien, A.Amselem, G.Cumano, A.Baroud, C. N.2019-01-08doi:10.1101/514158Cold Spring Harbor Laboratory Press2019-01-08
<![CDATA[
Description of Klebsiella africanensis sp. nov., Klebsiella variicola subsp. tropicalensis subsp. nov. and Klebsiella variicola subsp. variicola subsp. nov.
]]>
https://biorxiv.org/cgi/content/short/516278v1?rss=1"
Rodrigues, C.Passet, V.Rakotondrasoa, A.Diallo, T. A.Criscuolo, A.Brisse, S.2019-01-09doi:10.1101/516278Cold Spring Harbor Laboratory Press2019-01-09
<![CDATA[
HSA+ immature cardiomyocytes persist in the adult heart and expand after ischemic injury
]]>
https://biorxiv.org/cgi/content/short/518530v1?rss=1"
Valente, M.Resende, T. P.Nascimento, D. S.Burlen-Defranoux, O.Dupont, B.Cumano, A.Pinto-do-O, P.2019-01-13doi:10.1101/518530Cold Spring Harbor Laboratory Press2019-01-13
<![CDATA[
Impact and evolutionary determinants of Neanderthal introgression on transcriptional and post-transcriptional regulation
]]>
https://biorxiv.org/cgi/content/short/532366v1?rss=1"
Silvert, M.Quintana-Murci, L.Rotival, M.2019-01-28doi:10.1101/532366Cold Spring Harbor Laboratory Press2019-01-28
<![CDATA[
Gut microbiota requires vagus nerve integrity to promote depression
]]>
https://biorxiv.org/cgi/content/short/547778v1?rss=1"
Siopi, E.Saha, S.Moigneu, C.Bigot, M.Lledo, P.-M.2019-02-13doi:10.1101/547778Cold Spring Harbor Laboratory Press2019-02-13
<![CDATA[
Cryptococcus neoformans resist to drastic conditions by switching to viable but non-culturable cell phenotype
]]>
https://biorxiv.org/cgi/content/short/552836v1?rss=1"
Hommel, B.Sturny-Leclere, A.Volant, S.Veluppillai, N.Duchateau, M.Yu, C.-H.Hourdel, V.Varet, H.Matondo, M.Perfect, J. R.Casadevall, A.Dromer, F.Alanio, A.2019-02-18doi:10.1101/552836Cold Spring Harbor Laboratory Press2019-02-18
<![CDATA[
Transcriptome-wide dynamics of extensive m6A mRNA methylation during Plasmodium falciparum blood-stage development
]]>
https://biorxiv.org/cgi/content/short/572891v1?rss=1"
Baumgarten, S.Bryant, J. M.Sinha, A.Reyser, T.Preiser, P. R.Dedon, P. C.Scherf, A.2019-03-09doi:10.1101/572891Cold Spring Harbor Laboratory Press2019-03-09
<![CDATA[
Recombination-independent recognition of DNA homology for meiotic silencing in Neurospora crassa
]]>
https://biorxiv.org/cgi/content/short/573907v1?rss=1"
Rhoades, N.Cecere, G.Hammond, T.Gladyshev, E.2019-03-11doi:10.1101/573907Cold Spring Harbor Laboratory Press2019-03-11
<![CDATA[
Diversification of the type IV filament super-family into machines for adhesion, secretion, DNA transformation and motility
]]>
https://biorxiv.org/cgi/content/short/576694v1?rss=1"
Denise, R.Abby, S. S.Rocha, E. P.2019-03-13doi:10.1101/576694Cold Spring Harbor Laboratory Press2019-03-13
<![CDATA[
A peptide of a type I toxin-antitoxin system induces Helicobacter pylori morphological transformation from spiral-shape to coccoids
]]>
https://biorxiv.org/cgi/content/short/585380v1?rss=1"
El Mortaji, L.Marsin, S.Rifflet, A.Boneca, I. G.Radicella, P.Pehau-Arnaudet, G.De Reuse, H.2019-03-21doi:10.1101/585380Cold Spring Harbor Laboratory Press2019-03-21
<![CDATA[
Polygenic architecture of human neuroanatomical diversity
]]>
https://biorxiv.org/cgi/content/short/592337v1?rss=1"
26,000 individuals from the UK Biobank project and 5 other projects that had previously participated in the ENIGMA consortium. Our results confirm the polygenic architecture of neuroanatomical diversity, with SNPs capturing from 40% to 54% of regional brain volume variance. Chromosomal length correlated with the amount of phenotypic variance captured, r[~]0.64 on average, suggesting that at a global scale causal variants are homogeneously distributed across the genome. At a local scale, SNPs within genes ([~]51%) captured [~]1.5 times more genetic variance than the rest; and SNPs with low minor allele frequency (MAF) captured less variance than the rest: the 40% of SNPs with MAF<5% captured <1/4th of the genetic variance. We also observed extensive pleiotropy across regions, with an average genetic correlation of rG[~]0.45. Genetic correlations were similar to phenotypic and environmental correlations, however, genetic correlations were often larger than phenotypic correlations for the left/right volumes of the same region. The heritability of differences in left/right volumes was generally not statistically significant, suggesting an important influence of environmental causes in the variability of brain asymmetry. Our code is available at https://github.com/neuroanatomy/genomic-architecture.
]]>Biton, A.Traut, N.Poline, J.-B.Aribisala, B. S.Bastin, M. E.Bülow, R.Cox, S. R.Deary, I. J.Grabe, H. J.Hagenaars, S.Hashimoto, R.Munoz Maniega, S.Nauck, M.Royle, N. A.Teumer, A.Valdes Hernandez, M.Völker, U.Wardlaw, J. M.Wittfeld, K.Alzheimer's Disease Neuroimaging Initiative,Bourgeron, T.Toro, R.2019-03-28doi:10.1101/592337Cold Spring Harbor Laboratory Press2019-03-28
<![CDATA[
Identification and characterization of OmpT-like proteases in uropathogenic Escherichia coli clinical isolates
]]>
https://biorxiv.org/cgi/content/short/594564v1?rss=1"
Desloges, I.Taylor, J. A.Leclerc, J.-M.Brannon, J. R.Portt, A.Spencer, J. D.Dewar, K.Marczynski, G. T.Manges, A.Gruenheid, S.Le Moual, H.Thomassin, J.-L.2019-04-04doi:10.1101/594564Cold Spring Harbor Laboratory Press2019-04-04
<![CDATA[
Macromolecular crowding links ribosomal protein gene dosage to growth rate in Vibrio cholerae.
]]>
https://biorxiv.org/cgi/content/short/619304v1?rss=1"
Soler-Bistue, A.Aguilar-Pierle, S.Garcia-Garcera, M.Val, M.-E.Sismeiro, O.Varet, H.Sieira, R.Krin, E.Skovgaard, O.Comerci, D. J.Rocha, E. P.Mazel, D.2019-04-25doi:10.1101/619304Cold Spring Harbor Laboratory Press2019-04-25
<![CDATA[
Modeling cell infection via virus-producing cells rather than free infectious virus significantly improves fits of an in vitro viral kinetic data
]]>
https://biorxiv.org/cgi/content/short/627968v1?rss=1"
Bernhauerova, V.Rezelj, V. V.Laura, L. I.Vignuzzi, M.2019-05-05doi:10.1101/627968Cold Spring Harbor Laboratory Press2019-05-05
<![CDATA[
Comparative analysis of neuroinvasion by Japanese encephalitis virulent and vaccine strains in an in cellulo model of human blood-brain barrier
]]>
https://biorxiv.org/cgi/content/short/642033v1?rss=1"
Khou, C.Diaz-Salinas, M. A.da Costa, A.Prehaud, C.Jeannin, P.Afonso, P.Vignuzzi, M.Lafon, M.Pardigon, N.2019-05-19doi:10.1101/642033Cold Spring Harbor Laboratory Press2019-05-19
<![CDATA[
Systematic exploration of protein conformational space using a Distance Geometry approach
]]>
https://biorxiv.org/cgi/content/short/650903v1?rss=1"
Malliavin, T. E.Mucherino, A.Lavor, C.Liberti, L.2019-05-27doi:10.1101/650903Cold Spring Harbor Laboratory Press2019-05-27
<![CDATA[
Lineage hierarchies and stochasticity ensure the long-term maintenance of adult neural stem cells
]]>
https://biorxiv.org/cgi/content/short/663922v1?rss=1"
Than-Trong, E.Kiani, B.Dray, N.Ortica, S.Simons, B. D.Rulands, S.Alunni, A.Bally-Cuif, L.2019-06-09doi:10.1101/663922Cold Spring Harbor Laboratory Press2019-06-09
<![CDATA[
CD44 alternative splicing is a sensor of intragenic DNA methylation in tumors
]]>
https://biorxiv.org/cgi/content/short/685651v1?rss=1"
Batsche, E.Mauger, O.Kornobis, E.Hopkins, B.Hamner-Llyod, C.Muchardt, C.2019-06-27doi:10.1101/685651Cold Spring Harbor Laboratory Press2019-06-27
<![CDATA[
An impact of HP1γ on the fidelity of pre-mRNA splicing arises from its ability to bind RNA via intronic repeated sequences.
]]>
https://biorxiv.org/cgi/content/short/686790v1?rss=1"
Rachez, C.Legendre, R.Costallat, M.Varet, H.Yi, J.Kornobis, E.Proux, C.Muchardt, C.2019-06-28doi:10.1101/686790Cold Spring Harbor Laboratory Press2019-06-28
<![CDATA[
Listeria monocytogenes exploits the MICOS complex subunit Mic10 to promote mitochondrial fragmentation and cellular infection
]]>
https://biorxiv.org/cgi/content/short/712067v1?rss=1"
Carvalho, F.Spier, A.Chaze, T.Matondo, M.Cossart, P.Stavru, F.2019-07-23doi:10.1101/712067Cold Spring Harbor Laboratory Press2019-07-23
<![CDATA[
JASS: Command Line and Web interface for the joint analysis of GWAS results
]]>
https://biorxiv.org/cgi/content/short/714832v1?rss=1"
Julienne, H.Lechat, P.Guillemot, V.Lasry, C.Yao, C.Laville, V.Vilhjalmsson, B.Menager, H.Aschard, H.2019-07-25doi:10.1101/714832Cold Spring Harbor Laboratory Press2019-07-25
<![CDATA[
Transpeptidase PBP2 governs initial localization and activity of major cell-wall synthesis machinery in Escherichia coli
]]>
https://biorxiv.org/cgi/content/short/716407v1?rss=1"
Wollrab, E.Ozbaykal, G.Vigouroux, A.Cordier, B.Simon, F.Chaze, T.Matondo, M.van Teeffelen, S.2019-07-28doi:10.1101/716407Cold Spring Harbor Laboratory Press2019-07-28
<![CDATA[
Dynamics of Livestock-Associated Methicillin Resistant Staphylococcus aureus in pig farms networks: insight from mathematical modeling and French data
]]>
https://biorxiv.org/cgi/content/short/727032v1?rss=1"
Bastard, J.Andraud, M.Chauvin, C.Glaser, P.Opatowski, L.Temime, L.2019-08-06doi:10.1101/727032Cold Spring Harbor Laboratory Press2019-08-06
<![CDATA[
Mosaic heterochrony in neural progenitors sustains accelerated brain growth and neurogenesis in the juvenile killifish N. furzeri
]]>
https://biorxiv.org/cgi/content/short/747477v1?rss=1"
Coolen, M.Labusch, M.Mannioui, A.Hoppe, B.Baumgart, M.Bally-Cuif, L.2019-08-28doi:10.1101/747477Cold Spring Harbor Laboratory Press2019-08-28
<![CDATA[
Pneumococcal carriage requires KDM6B, a histone demethylase, for its unique inflammatory signature
]]>
https://biorxiv.org/cgi/content/short/757906v1?rss=1"
Connor, M. G.Patey, E.Rasid, O.Barrio, L.Miller, D. P.Lamont, R. J.Enninga, J.Hamon, M. A.2019-09-06doi:10.1101/757906Cold Spring Harbor Laboratory Press2019-09-06
<![CDATA[
Bacteria control cell volume by coupling cell-surface expansion to dry-mass growth
]]>
https://biorxiv.org/cgi/content/short/769786v1?rss=1"
Oldewurtel, E. R.Kitahara, Y.Cordier, B.Özbaykal, G.van Teeffelen, S.2019-09-16doi:10.1101/769786Cold Spring Harbor Laboratory Press2019-09-16
<![CDATA[
Reduced RNA turnover as a driver of cellular senescence
]]>
https://biorxiv.org/cgi/content/short/800128v1?rss=1"
Mullani, N.Costallat, M.Batsche, E.Porozhan, Y.Guerrera, C.Goodhardt, M.Cenci, G.Muchardt, C.2019-10-14doi:10.1101/800128Cold Spring Harbor Laboratory Press2019-10-14
<![CDATA[
Transient Nodal signalling in left precursors coordinates opposed asymmetries shaping the heart loop
]]>
https://biorxiv.org/cgi/content/short/854463v1?rss=1"
Desgrange, A.Le Garrec, J.-F.Bernheim, S.Holm Bonnelykke, T.Meilhac, S.2019-11-25doi:10.1101/854463Cold Spring Harbor Laboratory Press2019-11-25
<![CDATA[
Direct interaction between RSV polymerase L and active Rab11a mediates viral ribonucleoprotein transport to assembly sites
]]>
https://biorxiv.org/cgi/content/short/2025.10.28.685001v1?rss=1"
GIRY, C.JIMENEZ, A. J.DE OLIVEIRA, J.OKHRAVIJOUYBARI, F.BESSONNE, M.HUARD DE VERNEUIL, A.ENGLAND, P.SUTTO-ORTIZ, P.CHEVRET, D.TAHIR, A.DEBART, F.DECROLY, E.SOURIMANT, J.Rameix-Welti, M.-A.2025-10-28doi:10.1101/2025.10.28.685001Cold Spring Harbor Laboratory Press2025-10-28
<![CDATA[
Genome-scale CRISPRi profiling reveals metabolic vulnerabilities of uropathogenic Escherichia coli in human urine
]]>
https://biorxiv.org/cgi/content/short/2025.10.31.685768v1?rss=1"
Ortelli, M.Prakapaite, R.Müller, A.Miele, S. A. B.Fino, C.Klimke, S.Tschudin-Sutter, S.Jenal, U.de Bento Flores, C. E.Bikard, D.Dehio, C.2025-10-31doi:10.1101/2025.10.31.685768Cold Spring Harbor Laboratory Press2025-10-31
<![CDATA[
Identification of protein secretion systems in bacterial genomes using MacSyFinder version 2.
]]>
https://biorxiv.org/cgi/content/short/2023.01.06.522999v1?rss=1"
Abby, S. S.Denise, R.Rocha, E. P.2023-01-06doi:10.1101/2023.01.06.522999Cold Spring Harbor Laboratory Press2023-01-06
<![CDATA[
MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes
]]>
https://biorxiv.org/cgi/content/short/2022.09.02.506364v1?rss=1"
Neron, B.Denise, R.Coluzzi, C.Touchon, M.Rocha, E. P. C.Abby, S. S.2022-09-04doi:10.1101/2022.09.02.506364Cold Spring Harbor Laboratory Press2022-09-04
<![CDATA[
The two groups of zebrafish type I interferons target different tissues, paralleling the mammalian type I: type III IFN functional division
]]>
https://biorxiv.org/cgi/content/short/2025.11.03.686239v1?rss=1"
Wiggett, H.Porter, D.Briolat, V.Balaboi, T.Abi Younes, M.Colin, I.Lutfalla, G.Levraud, J.-P.2025-11-04doi:10.1101/2025.11.03.686239Cold Spring Harbor Laboratory Press2025-11-04
<![CDATA[
AXL mediates mast cell survival and resistance to tyrosine kinase inhibitors in mastocytosis
]]>
https://biorxiv.org/cgi/content/short/2025.11.03.686205v1?rss=1"
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org.highwire.dtl.DTLVardef@1569c9eorg.highwire.dtl.DTLVardef@1445b32org.highwire.dtl.DTLVardef@bf3565org.highwire.dtl.DTLVardef@14a94f0_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>Kangboonruang, K.Drabent, P.Heintze, M.Maksut, F.Lepelletier, Y.Lhermitte, L.Feroul, M.Letard, S.Kabore, C.Brenet, F.Meni, C.Cagnard, N.Bondet, V.Lefevre, G.Bruneau, J.Dussiot, M.Halse, H.Bigorgne, A.Collange, A.-F.Bouktit, H.Retornaz, F.Megret, J.Barete, S.Droin, N.Bulai Livideanu, C.Lebouvier, A.Duffy, D.Solary, E.Arock, M.Gandhi, D.Bodemer, C.Rossignol, J.Polivka, L.Molina, T.Hermine, O.Maouche-Chretien, L.2025-11-04doi:10.1101/2025.11.03.686205Cold Spring Harbor Laboratory Press2025-11-04
<![CDATA[
The genetic driver of Acute Necrotizing Encephalopathy, RANBP2, regulates the inflammatory response to Influenza A virus infection
]]>
https://biorxiv.org/cgi/content/short/2025.03.23.644734v1?rss=1"
Desgraupes, S.Gouy, B.Perrin, S.Decorsiere, A.Wang, Y. E.Palazzo, A. F.Arhel, N. J.2025-03-25doi:10.1101/2025.03.23.644734Cold Spring Harbor Laboratory Press2025-03-25
<![CDATA[
The pupal stage is a developmental window for RNA virus persistence in Drosophila
]]>
https://biorxiv.org/cgi/content/short/2025.11.07.687216v1?rss=1"
Castello-Sanjuan, M.Gonzalez, R.Bergman, A.Blanc, H.Frangeul, L.Nigg, J.Saleh, M.-C.2025-11-07doi:10.1101/2025.11.07.687216Cold Spring Harbor Laboratory Press2025-11-07
<![CDATA[
Morphogenesis and morphometry of brain folding patterns across species
]]>
https://biorxiv.org/cgi/content/short/2025.03.05.641692v1?rss=1"
Yin, S.Liu, C.Choi, G. P. T.Jung, Y.Heuer, K.Toro, R.Mahadevan, L.2025-03-10doi:10.1101/2025.03.05.641692Cold Spring Harbor Laboratory Press2025-03-10
<![CDATA[
Strain-level translocation and enrichment mechanisms of oral bacteria in the lower gastrointestinal tract of stunted children
]]>
https://biorxiv.org/cgi/content/short/2025.11.11.687814v1?rss=1"
Yersin, S.Gody, J.-C.Mazel, F.Djmbele, E.Nigateloum, C.Gondje, B. P.Vondo, S. S.Kandou, K.Raub, A.Teo, Y.Djorie, S.Kapel, N.Sansonetti, P.Vonaesch, P.Afribiota Investigators,2025-11-11doi:10.1101/2025.11.11.687814Cold Spring Harbor Laboratory Press2025-11-11
<![CDATA[
Pathogenic Keratinocyte States and Fibroblast Niches Define the Tissue Microenvironment in Severe Hidradenitis Suppurativa
]]>
https://biorxiv.org/cgi/content/short/2025.11.11.682326v1?rss=1"
Du-Harpur, X.Ganier, C.Mazin, P.Cheshire, C.Rashidghamat, E.Luscombe, N. M.Lynch, M. D.Watt, F. M.2025-11-12doi:10.1101/2025.11.11.682326Cold Spring Harbor Laboratory Press2025-11-12
<![CDATA[
Snooping helices: The elastic path finding algorithm of growing hyphae
]]>
https://biorxiv.org/cgi/content/short/2025.11.12.685335v1?rss=1"
Rittaud, A.Couttenier, E.Bachellier-Bassi, S.D'Enfert, C.Kulic, I. M.Villard, C.2025-11-13doi:10.1101/2025.11.12.685335Cold Spring Harbor Laboratory Press2025-11-13
<![CDATA[
Engineering directional phosphoryl flow enables programmable signaling dynamics in bacteria
]]>
https://biorxiv.org/cgi/content/short/2025.11.17.688798v1?rss=1"
Nieves, M.Valle, J. M.Dalla Rizza, J.Carrion, F.Naranjo-Meneses, P.Larrieux, N.Bischofs, I.Buschiazzo, A.Trajtenberg, F.2025-11-17doi:10.1101/2025.11.17.688798Cold Spring Harbor Laboratory Press2025-11-17
<![CDATA[
Natural diversity of telomere length distributions across 100 yeast strains
]]>
https://biorxiv.org/cgi/content/short/2025.05.13.653712v1?rss=1"
Garrido, C.Kornobis, E.Agier, N.Ilioaia, O.Fischer, G.Xu, Z.2025-05-16doi:10.1101/2025.05.13.653712Cold Spring Harbor Laboratory Press2025-05-16
<![CDATA[
Characterizing drug activity with sensitive interactomes in human living cells
]]>
https://biorxiv.org/cgi/content/short/2025.11.20.689448v1?rss=1"
Kundlacz, C.Sleiman, N. H.Marmigere, F.Gillet, B.Hughes, S.Gilquin, L.Duplus-Bottin, H.Dumont, A.Yvert, G.Bleicher, F.Gautier, A.Coste, I.Renno, T.Merabet, S.2025-11-23doi:10.1101/2025.11.20.689448Cold Spring Harbor Laboratory Press2025-11-23
<![CDATA[
Coordinated shifts in gene expression and regulation during mole-rat evolution
]]>
https://biorxiv.org/cgi/content/short/2025.11.24.690111v1?rss=1"
Daunesse, M.Liorzou, E.Parey, E.Villar Lozano, D.BERTHELOT, C.2025-11-25doi:10.1101/2025.11.24.690111Cold Spring Harbor Laboratory Press2025-11-25
<![CDATA[
Tracking HIV-1 DNA fate from Cell Culture to Humanized mice Tissues.
]]>
https://biorxiv.org/cgi/content/short/2025.11.25.690387v1?rss=1"
Diana, J.-S.Tatirovsky, E.Tomasini, C.Cuche, C.Ay, S.Scoca, V.Cavazzana, M.Di Santo, J. P.Di Nunzio, F.2025-11-25doi:10.1101/2025.11.25.690387Cold Spring Harbor Laboratory Press2025-11-25
<![CDATA[
Cumulative cgMLST provides increased discrimination of nested phylogenetic groups
]]>
https://biorxiv.org/cgi/content/short/2025.11.25.689980v1?rss=1"
99% in the validation datasets. Compared to the KpSC scheme used alone, pairwise allelic distances among isolates increased on average 5.6-fold using the Kpn scheme, and further by 20% and 30% using the SL147 and SL307 schemes, respectively. We demonstrate the added value of this increased discriminatory power for epidemiological analyses and show nearly equal discrimination when compared to whole-genome single nucleotide polymorphisms analysis.
ConclusionsThe cumulative cgMLST strategy combines broad phylogenetic applicability and nearly complete genotyping resolution, expanding the utility of this harmonized approach for genomic epidemiology.
]]>Ovsepian, A.Delgado-Blas, J.Rethoret-Pasty, M.Martin, M. J.Lebreton, F.Brisse, S.2025-11-26doi:10.1101/2025.11.25.689980Cold Spring Harbor Laboratory Press2025-11-26
<![CDATA[
Tripartite ER-Mitochondria-Lipid Droplets contact sites control adipocyte metabolic flexibility
]]>
https://biorxiv.org/cgi/content/short/2025.09.16.676493v1?rss=1"
Palard, M.Chadeuf, G.Carpentier, M.Frey, S.Croyal, M.Shaaban, R.Hadjadj, S.Cloteau, C.Elkhallouki, N.Bomme, P.Le Lay, S.Combot, Y.Marjouh, M.Paul-Gilloteaux, P.Antreou, A.Le May, C.Ducheix, S.Cariou, B.Giordano, F.Rieusset, J.Thiam, A. R.Prieur, X.2025-09-18doi:10.1101/2025.09.16.676493Cold Spring Harbor Laboratory Press2025-09-18
<![CDATA[
Extending digital biology: bacterial survival and morphological heterogeneity under antibiotic stress
]]>
https://biorxiv.org/cgi/content/short/2025.11.25.690353v1?rss=1"
Maikranz, E.Aristov, A.Le Quellec, L.Baroud, C.2025-11-28doi:10.1101/2025.11.25.690353Cold Spring Harbor Laboratory Press2025-11-28
<![CDATA[
Nanoscale imaging of native symbiotic animal tissue using amultimodal large volume imaging pipeline for cryo-electrontomography
]]>
https://biorxiv.org/cgi/content/short/2025.11.30.691379v1?rss=1"
Gundlach, K. A.Schiotz, O. H.Ladinsky, M. S.Raimann, C.Rheinberger, M.Beck, F.Guenduez, B.Langelaan, R.Ruecklin, M.Limpens, R. W. A. L.Ruby, E. G.McFall-Ngai, M.Plitzko, J. M.Briegel, A.2025-11-30doi:10.1101/2025.11.30.691379Cold Spring Harbor Laboratory Press2025-11-30
<![CDATA[
Nuclear activities and interactome of the NS5 protein of Tick-Borne Encephalitis Virus
]]>
https://biorxiv.org/cgi/content/short/2025.11.29.691275v1?rss=1"
Chazal, M.Sow, A.-A.Le Seac'h, E.Hawasheen, D.Bonifacio, M.Feracci, M.Gracias, S.Sogues, A.Molho, M.Pan, H.Bonaventure, B.Quivy, J.-P.Almouzni, G.Decroly, E.Ramage, H.Johnson, J. R.Caval, v.jouvenet, n.2025-11-30doi:10.1101/2025.11.29.691275Cold Spring Harbor Laboratory Press2025-11-30
<![CDATA[
Soluble and insoluble dietary fibres differentially affect liver steatosis and gut microbiota in western-diet fed mice
]]>
https://biorxiv.org/cgi/content/short/2025.11.26.690531v1?rss=1"
Martin, C. M. P.Miquel, M.Alquier-Bacquie, V.Polizzi, A.Lasserre, F.Huillet, M.Rives, C.Bruse, J.Jarrasier, J.Perrier, P.Gomes, J.Naylies, C.Dauriat, C.Geoffre, N.Durbec, A.Duchampt, A.Thirault, A.Blanc, X.Rousseau-Bacquie, E.Lippi, Y.Bertrand-Michel, J.Canlet, C.Chassaing, B.Fougerat, A.Gamet-Payrastre, L.Gautier-Stein, A.Guilllou, H.Loiseau, N.Ellero-Simatos, S.2025-12-01doi:10.1101/2025.11.26.690531Cold Spring Harbor Laboratory Press2025-12-01
<![CDATA[
Local B cell maturation and mast cell regulation of choroid plexus function in early life.
]]>
https://biorxiv.org/cgi/content/short/2025.11.27.690721v1?rss=1"
Ali-Moussa, S.Blas-Medina, A.Josephides, J.Mirabeau, O.Bouteau, I.Matijevic, T.Kovacs, M.Pakulska, V.Pangan, A. R.Thomas, C.Hasselblatt, M.Dong, X.Matondo, M.Gaudenzio, N.Jonsson, F.Travier, L.Deczkowska, A.2025-12-01doi:10.1101/2025.11.27.690721Cold Spring Harbor Laboratory Press2025-12-01
<![CDATA[
SNooPy: a statistical framework for long-read metagenomic variant calling
]]>
https://biorxiv.org/cgi/content/short/2025.12.01.691549v1?rss=1"
Faure, R.Faure, U.Truong, T. M. K.Derzelle, A.Lavenier, D.Flot, J.-F.Quince, C.2025-12-02doi:10.64898/2025.12.01.691549Cold Spring Harbor Laboratory Press2025-12-02
<![CDATA[
Integrated protein-protein interaction and RNA interference screens reveal novel restriction and dependency factors for a tick-borne flavivirus in its human host
]]>
https://biorxiv.org/cgi/content/short/2022.11.03.514869v1?rss=1"
Sourisseau, M.Unterfinger, Y.Lemasson, M.Caignard, G.Piumi, F.Grot, A.Moutailler, S.Vitour, D.Coulpier, M.Lacour, S. A.Richardson, J.2022-11-04doi:10.1101/2022.11.03.514869Cold Spring Harbor Laboratory Press2022-11-04
<![CDATA[
Actin and myosin dynamics during epithelial remodeling in avian gastrulation
]]>
https://biorxiv.org/cgi/content/short/2025.12.05.692587v1?rss=1"
Ieda, Y.Phan, C.Alegria-Prevot, O.Villedieu, A.Gros, J.2025-12-05doi:10.64898/2025.12.05.692587Cold Spring Harbor Laboratory Press2025-12-05
<![CDATA[
Detection and phylogenetic characterization of Jingmen tick virus in Amblyomma mixtum ticks from Costa Rica
]]>
https://biorxiv.org/cgi/content/short/2025.12.05.692540v1?rss=1"
Murillo, T.Chaves-Gonzalez, L. E.Temmam, S.Bermudez, S.Corrales-Aguilar, E.Montenegro, V. M.Dheilly, N.Troyo, A.2025-12-07doi:10.64898/2025.12.05.692540Cold Spring Harbor Laboratory Press2025-12-07
<![CDATA[
Intracellular amorphous calcium carbonate biomineralization in methanotrophic gammaproteobacteria was acquired by horizontal gene transfer from cyanobacteria
]]>
https://biorxiv.org/cgi/content/short/2025.12.07.689555v1?rss=1"
Benzerara, K.Millet, M. L.Skouri-Panet, F.Gaschignard, G.Mehta, N.Bezard, M.Caumes, G.Chevrier, D.Dezi, M.Duverger, A.Guigner, J.-M.Gutierrez-Preciado, A.Lefevre, C. T.Lopez-Garcia, P.Menguy, N.Monteil, C. L.Pehau-Arnaudet, G.Penard, E.Pereiro, E.Scandola, C.Travert, C.Vantelon, D.Duprat, E.Callebaut, I.Moreira, D.2025-12-07doi:10.64898/2025.12.07.689555Cold Spring Harbor Laboratory Press2025-12-07
<![CDATA[
A Pair of DNA Glucosyltransferases Elevate Counter-defense in Bacteriophage T4
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https://biorxiv.org/cgi/content/short/2025.12.06.692756v1?rss=1"
Ramirez-Chamorro, L.Bonhomme, F.Wolff, A. L. I.Lecointe, F.Hollenstein, M.Krupovic, M.De Paepe, M.Bhoobalan-Chitty, Y.2025-12-07doi:10.64898/2025.12.06.692756Cold Spring Harbor Laboratory Press2025-12-07
<![CDATA[
Low-dimensional neuronal population dynamics in anterior superior temporal gyrus reactivate phonetic representations during semantic processing
]]>
https://biorxiv.org/cgi/content/short/2023.10.30.564638v1?rss=1"
Orepic, P.Truccolo, W.Cash, S. S.Giraud, A.-L.Proix, T.2023-10-31doi:10.1101/2023.10.30.564638Cold Spring Harbor Laboratory Press2023-10-31
<![CDATA[
IFN-I exacerbates the inflammatory response of epithelial cells to Chlamydia trachomatis infection by enhancing TLR3 expression
]]>
https://biorxiv.org/cgi/content/short/2025.12.08.692940v1?rss=1"
Tang, C.Cai, X.Niragire, B.Louchez, F.Levy-Zauberman, Y. V.Subtil, A.Wu, Y.2025-12-08doi:10.64898/2025.12.08.692940Cold Spring Harbor Laboratory Press2025-12-08
<![CDATA[
Ancestry, admixture, and pathogens in contemporaneous Neolithic farmers and foragers on the Island of Gotland
]]>
https://biorxiv.org/cgi/content/short/2025.12.07.692553v1?rss=1"
Fraser, M.Sanchez-Quinto, F.Kırdökc, E.Ausmees, K.Kılınc, G. M.Larena, M.Correa-Mendoza, L.Le Meur, A.Blanchet, A.Bergfeldt, N.Arrieta-Donato, E.Escobar-Rodriguez, M.Götherström, A.Lozano-Gonzalez, K.Aguilar-Ordonez, I.Malmström, H.Knutsson, K.Wallin, P.Rascovan, N.Stora, J.Jakobsson, M.2025-12-10doi:10.64898/2025.12.07.692553Cold Spring Harbor Laboratory Press2025-12-10
<![CDATA[
Inverted colored de Bruijn Graph for practical kmer sets storage
]]>
https://biorxiv.org/cgi/content/short/2025.12.08.692073v1?rss=1"
Rouze, T.Chikhi, R.Limasset, A.2025-12-10doi:10.64898/2025.12.08.692073Cold Spring Harbor Laboratory Press2025-12-10
<![CDATA[
ProteoBench: the community-curated platform for comparing proteomics data analysis workflows
]]>
https://biorxiv.org/cgi/content/short/2025.12.09.692895v1?rss=1"
Devreese, R.Jachmann, C.Van Puyvelde, B.Anagho-Mattanovich, H. A.Wolski, W. E.Webel, H.Anagho-Mattanovich, M.Bittremieux, W.Chaoui, K.Chiva, C.Claeys, T.Castaneda Cortes, H. M.Devos, S.Dhaenens, M.Doncheva, N. T.Dorfer, V.Eisenacher, M.Gabriels, R.Giai Gianetto, Q.Hollenstein, D. M.Jensen, L. J.Kasalica, V.Langella, O.Lennartsson, C.Lux, D.Martens, L.Matondo, M.Mendes Maia, T.Mouton-Barbosa, E.Nameni, A.Nielsen, M. L.Olsen, J. V.Palmblad, M.Panse, C.Perez-Riverol, Y.Pominova, M.Rykaer, M.Sabido, E.Schessner, J.Schnei2025-12-11doi:10.64898/2025.12.09.692895Cold Spring Harbor Laboratory Press2025-12-11
<![CDATA[
Engineering SIRPα conformational plasticity to reveal a cryptic pocket suitable for structure-based drug design
]]>
https://biorxiv.org/cgi/content/short/2025.12.10.693509v1?rss=1"
Storder, M.Barelier, S.Cordier, F.YACOUB, T.Ilari, L.Barral, K.MAHMOODI, S.Saez-Ayala, M.Combes, S.Betzi, S.Ulliana, A.Torres, F.Rubin, J.Roche, P.Morelli, X.Garcin, E. D.Miller, T. W.2025-12-11doi:10.64898/2025.12.10.693509Cold Spring Harbor Laboratory Press2025-12-11
<![CDATA[
Mastodon: the Command Center for Large-Scale Lineage-Tracing Microscopy Datasets
]]>
https://biorxiv.org/cgi/content/short/2025.12.10.693416v1?rss=1"
Girstmair, J.Pietzsch, T.Ulman, V.Hahmann, S.Arzt, M.Handberg-Thorsager, M.Sugawara, K.Pantze, S.Haase, R.Tinevez, J.-Y.Tomancak, P.2025-12-12doi:10.64898/2025.12.10.693416Cold Spring Harbor Laboratory Press2025-12-12
<![CDATA[
Environment and physiology shape antiphage system expression
]]>
https://biorxiv.org/cgi/content/short/2025.12.14.694197v1?rss=1"
Paoli, L.Laruelle, B.Lavenir, R.Loubat, A.Tesson, F.Gaborieau, B.Bernheim, A.2025-12-14doi:10.64898/2025.12.14.694197Cold Spring Harbor Laboratory Press2025-12-14
<![CDATA[
Coupled rhythms in early auditory cortex mirror speech acoustics
]]>
https://biorxiv.org/cgi/content/short/2025.10.22.683926v1?rss=1"
Lopez-Madrona, V. J.Giroud, J.Mercier, M.Lancia, L.Giordano, B. L.Trebuchon, A.Poeppel, D.Giraud, A.-L.Arnal, L.Morillon, B. L.2025-10-23doi:10.1101/2025.10.22.683926Cold Spring Harbor Laboratory Press2025-10-23
<![CDATA[
scPRINT-2: Towards the next-generation of cell foundation models and benchmarks
]]>
https://biorxiv.org/cgi/content/short/2025.12.11.693702v1?rss=1"
Kalfon, J.Peyre, G.Cantini, L.2025-12-15doi:10.64898/2025.12.11.693702Cold Spring Harbor Laboratory Press2025-12-15
<![CDATA[
Bacteriophage PAK_P3 genome structuration and dynamics during infection of Pseudomonas aeruginosa reveal specific interactions patterns
]]>
https://biorxiv.org/cgi/content/short/2025.12.15.694284v1?rss=1"
Bignaud, A.Lamy-Besnier, Q.Conti, D.Thierry, A.Girard, F.Misson, P.Koszul, R.Debarbieux, L.Marbouty, M.2025-12-15doi:10.64898/2025.12.15.694284Cold Spring Harbor Laboratory Press2025-12-15
<![CDATA[
Control of cellular cortical tension and shape by RhoGTPase signalling
]]>
https://biorxiv.org/cgi/content/short/2025.12.15.694413v1?rss=1"
Bohec, P.Khoromskaia, D.Kelkar, M.Ferber, E.Duprez, G.Lavoie, G.Valon, L.Roux, P. P.Salbreux, G.Charras, G.2025-12-17doi:10.64898/2025.12.15.694413Cold Spring Harbor Laboratory Press2025-12-17
<![CDATA[
The microbiota affects energy production, nitrogen excretion and sterol metabolism in mosquito larvae
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https://biorxiv.org/cgi/content/short/2025.12.17.695059v1?rss=1"
Romoli, O.Epelboina, Y.Pavoncello, V.Barras, F.Behrends, V.Gendrin, M.2025-12-18doi:10.64898/2025.12.17.695059Cold Spring Harbor Laboratory Press2025-12-18
<![CDATA[
The Lsm1-7 complex marginally affects unstable mRNA degradation in yeast
]]>
https://biorxiv.org/cgi/content/short/2025.12.17.694855v1?rss=1"
Decourty, L.Namane, A.Janbon, G.Saveanu, C.2025-12-18doi:10.64898/2025.12.17.694855Cold Spring Harbor Laboratory Press2025-12-18
<![CDATA[
Pangenome structure and ecological adaptation in the Klebsiella pneumoniae species complex: insights from a geographically and time limited multi-habitat study
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https://biorxiv.org/cgi/content/short/2025.12.11.693626v1?rss=1"
Delgado-Blas, J. F.Barbier, E.Passet, V.Neuwirth, C.Brisse, S.Rodrigues, C.Piveteau, P.2025-12-12doi:10.64898/2025.12.11.693626Cold Spring Harbor Laboratory Press2025-12-12
<![CDATA[
Limitations of non-mechanistic methods for characterizing pathogen-pathogen interactions: A simulation study
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https://biorxiv.org/cgi/content/short/2025.12.22.695879v1?rss=1"
Kramer, S. C.Pirikahu, S.Kussmaul, C.Opatowski, L.Domenech de Celles, M.2025-12-23doi:10.64898/2025.12.22.695879Cold Spring Harbor Laboratory Press2025-12-23
<![CDATA[
Wnt and Nodal asymmetries stratify mouse laterality phenotypes in the absence of node flow
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https://biorxiv.org/cgi/content/short/2025.12.21.695689v1?rss=1"
Ochandorena-Saa, A.Perthame, E.Oulerich, Z.Chamolly, A.Blisnick, T.Lokmer, J.Rouillon, C.Bastin, P.Meilhac, S. M.2025-12-23doi:10.64898/2025.12.21.695689Cold Spring Harbor Laboratory Press2025-12-23
<![CDATA[
Capsular specificity in temperate phages of Klebsiella pneumoniae is driven by diverse receptor-binding enzymes
]]>
https://biorxiv.org/cgi/content/short/2025.06.25.661490v1?rss=1"
Otwinowska, A.Koszucki, J.Panicker, V. R.Leconte, J.Olejniczak, S.Holt, K.Feil, E. J.Rocha, E. P. C.Smug, B.Maciejewska, B.Drulis-Kawa, Z.Mostowy, R. J.2025-06-25doi:10.1101/2025.06.25.661490Cold Spring Harbor Laboratory Press2025-06-25
<![CDATA[
Deep learning analyses of DNA sequences resolve the retention of the Duffy-null resistance to Plasmodium vivax malaria in Africa
]]>
https://biorxiv.org/cgi/content/short/2025.12.25.695976v1?rss=1"
Laval, G.Decugis, A.Parasayan, O.Patin, E.Quintana-Murci, L.Chiaroni, J.2025-12-26doi:10.64898/2025.12.25.695976Cold Spring Harbor Laboratory Press2025-12-26
<![CDATA[
Simulating magnetic rotational spectroscopy: a novel approach to intracellular rheology of adherent cells
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https://biorxiv.org/cgi/content/short/2025.07.07.663618v1?rss=1"
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<![CDATA[
Graft of cardiac progenitors in a pig model of right ventricular failure triggers myocardial epimorphosis, regeneration and protection of function
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https://biorxiv.org/cgi/content/short/2022.07.04.498652v1?rss=1"
LAMBERT, V.DELERIS, A.TIBOURTINE, F.FOUILLOUX, V.MARTIN, A.BRIDGE, P.ARIES, E.BENOIST, D.PUCEAT, M.2022-07-04doi:10.1101/2022.07.04.498652Cold Spring Harbor Laboratory Press2022-07-04
<![CDATA[
Stage-resolved metabolomics reveals the methionine cycle as a key regulator of Aedes aegypti development and dengue virus susceptibility
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https://biorxiv.org/cgi/content/short/2025.12.29.696135v1?rss=1"
Vial, T.Özhan, S.Dabo, S.Akorli, J.Marti, G.Merkling, S.2025-12-29doi:10.64898/2025.12.29.696135Cold Spring Harbor Laboratory Press2025-12-29
<![CDATA[
Template-based RNA structure prediction advanced through a blind code competition
]]>
https://biorxiv.org/cgi/content/short/2025.12.30.696949v1?rss=1"
Lee, Y.He, S.Oda, T.Rao, G. J.Kim, Y.Kim, R.Kim, H.Heng, C. K.Kowerko, D.Li, H.Nguyen, H.Sampathkumar, A.Enrique Gomez, R.Chen, M.Yoshizawa, A.Kuraishi, S.Ogawa, K.Zou, S.Paullier, A.Zhao, B.Chen, H.-L.Hsu, T.-A.Hirano, T.Gezelle, J. G.Haack, D.Hong, Y.Jadhav, S.Koirala, D.Kretsch, R. C.Lewicka, A.Li, S.Marcia, M.Piccirilli, J.Rudolfs, B.Srivastava, Y.Steckelberg, A.-L.Su, Z.Toor, N.Wang, L.Yang, Z.Zhang, K.Zou, J.Baker, D.Chen, S.-J.Chiu, W.Demkin, M.Favor, A.Hummer, A. M.Joshi, C. K.Kryshtafovyc2025-12-30doi:10.64898/2025.12.30.696949Cold Spring Harbor Laboratory Press2025-12-30
<![CDATA[
From fibril to framework: P. abyssi AbpX illuminates a calcium-responsive family of microbial biomatrix proteins that form thermostable hydrogels
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https://biorxiv.org/cgi/content/short/2026.01.04.697558v1?rss=1"
Sleutel, M.Sogues, A.Socorro, A. G.Fislage, M.Alva, V.Remaut, H.Conticello, V.2026-01-04doi:10.64898/2026.01.04.697558Cold Spring Harbor Laboratory Press2026-01-04
<![CDATA[
A Genome-Wide Genetic Screen Identifies a Novel kDNA Replication Protein in Trypanosomes
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https://biorxiv.org/cgi/content/short/2026.01.05.697628v1?rss=1"
Miskinyte, M.Jetishi, C.Kalichava, A.Ivens, A.Waterfall, M.Gould, M. K.Glover, L.Horn, D.Ochsenreiter, T.Schnaufer, A.2026-01-05doi:10.64898/2026.01.05.697628Cold Spring Harbor Laboratory Press2026-01-05
<![CDATA[
Time-Resolved Analysis of the Cell Wall Proteome in Saccharomyces cerevisiae S288c During Batch Fermentation
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https://biorxiv.org/cgi/content/short/2026.01.05.697623v1?rss=1"
Yammine, M.Picavet, A.Poilpre, E.Bray, F.Flament, S.Mouly, I.Rolando, C.2026-01-05doi:10.64898/2026.01.05.697623Cold Spring Harbor Laboratory Press2026-01-05
<![CDATA[
Decoding E. coli's Gut Survival Strategies: A CRISPRi Approach Across Diets, Inflammatory Environment and Strains
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https://biorxiv.org/cgi/content/short/2026.01.05.697630v1?rss=1"
Maire, A.Ortelli, M.Tkacz, E.Dehio, C.Chassaing, B.Sokol, H.Rolhion, N.Bikard, D.2026-01-05doi:10.64898/2026.01.05.697630Cold Spring Harbor Laboratory Press2026-01-05
<![CDATA[
Teddy: neural inference of epidemiological parameters from viral sequences
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https://biorxiv.org/cgi/content/short/2026.01.05.697728v1?rss=1"
Garot, V.Blassel, L.Nesterenko, L.ZHUKOVA, A.Alizon, S.Jacob, L.2026-01-05doi:10.64898/2026.01.05.697728Cold Spring Harbor Laboratory Press2026-01-05
<![CDATA[
Home is where the host is: Evolutionary history of geographic spread, host switching, and adaptive genomic signatures in two generalist Group B Streptococcus clonal groups
]]>
https://biorxiv.org/cgi/content/short/2026.01.06.697867v1?rss=1"
Hilbig, A.Crestani, C.Barkham, T.Chen, S. L.Cobo-Angel, C.Ceballos-Marquez, A.Sirimanapong, W.Amin-Nordin, S.Nguyen, P. N.Castro Abreu Pinto, T.Andrade de Oliveira, L. M.Garbarino, C. A.Ricchi, M.Lembo, T.Lycett, S. J.Biek, R.Forde, T. L.Zadoks, R. N.2026-01-06doi:10.64898/2026.01.06.697867Cold Spring Harbor Laboratory Press2026-01-06
<![CDATA[
Deep behavioral phenotyping of pathogen infected mosquitoes reveals species-specific behavior changes enhancing transmission
]]>
https://biorxiv.org/cgi/content/short/2026.01.06.697763v1?rss=1"
Wan, Z.Maire, T.Giraud, E.Kalyuzhnyy, V.van Gemert, G.-J.Lanke, K.Stoter, R.Mordmueller, B.Bousema, T.LAMBRECHTS, L.Hol, F. J.2026-01-06doi:10.64898/2026.01.06.697763Cold Spring Harbor Laboratory Press2026-01-06
<![CDATA[
LORA: a polymorphic multi-sample LOng Read Assembly pipeline.
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https://biorxiv.org/cgi/content/short/2026.01.06.697901v1?rss=1"
Desvillechabrol, D.Ouazahrou, R.Pipoli da Fonseca, J.Spaeth, G. F.Cokelaer, T.2026-01-07doi:10.64898/2026.01.06.697901Cold Spring Harbor Laboratory Press2026-01-07
<![CDATA[
ST8SIA4-mediated polysialylation is critical for CCR2-driven monocyte egress from the bone marrow
]]>
https://biorxiv.org/cgi/content/short/2026.01.09.698551v1?rss=1"
Boyance, A.Gilles, N.Rotival, M.Stella, A.Gorlt, C.Chaoui, K.Monard, S.Aguilo, N.Mangeat, T.Schiltz, O.Lortat-Jacob, H.Münster-Kühnel, A.Gonzalez de Peredo, A.Hudrisier, D.Quintana-Murci, L.Sadir, R.Hildebrandt, H.Neyrolles, O.Rombouts, Y.2026-01-12doi:10.64898/2026.01.09.698551Cold Spring Harbor Laboratory Press2026-01-12
<![CDATA[
Bacterial targeting of host paraspeckles uncovers a new SFPQ-based regulation
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https://biorxiv.org/cgi/content/short/2026.01.11.698932v1?rss=1"
NICCHI, S.Mondino, S.Rusniok, C.Mathal, N.Raynal, B.Elj, R.Giai Gianetto, Q.Dalla Rizza, J.Larrieux, N.Martyn, J.Schoeler, H.Schmutz, S.Mueller, F.Matondo, M.Buschiazzo, A.Buchrieser, C.Rolando, M.2026-01-12doi:10.64898/2026.01.11.698932Cold Spring Harbor Laboratory Press2026-01-12
<![CDATA[
Genomic Islands as minimal hitchers of conjugative elements
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https://biorxiv.org/cgi/content/short/2026.01.13.699239v1?rss=1"
Ares-Arroyo, M.Junker, R.Nucci, A.Touchon, M.Rocha, E. P. C.2026-01-13doi:10.64898/2026.01.13.699239Cold Spring Harbor Laboratory Press2026-01-13
<![CDATA[
Morphological transformation in Helicobacter pylori is a dynamic process leading to two types of coccoid
]]>
https://biorxiv.org/cgi/content/short/2026.01.13.698397v1?rss=1"
Cheng, T.Mai, P.-Y.Adedeji-Olulana, A. F.Smith, O. E. R.Wheeler, R.Berry, J.Hicham, S.Danot, O.Foster, S. J.Bharat, T. A. M.Hobbs, J. K.Gomperts Boneca, I.2026-01-13doi:10.64898/2026.01.13.698397Cold Spring Harbor Laboratory Press2026-01-13
<![CDATA[
SENOMORPHIC EFFECT OF GENETIC AND CHEMICAL PARTIAL REPROGRAMMING
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https://biorxiv.org/cgi/content/short/2026.01.13.699211v1?rss=1"
Nunez-Quintela, V.Chantrel, J.Prados, M. A.Pedrosa, P.Lorandi, I.Lorenzo Rodriguez, L.Chen, C.Paredes, R.Failde-Fiestras, A.Gonzalez-Perez, D.Miralles, A.Da Silva-Alvarez, S.Lobato-Busto, R.Gonzalez-Barcia, M.Alcon, C.Montero, J.Marques, P.Chondronasiou, D.Pietrocola, F.Serrano, M.Kovatcheva, M.Gomez-Duran, A.Li, H.Collado, M.2026-01-13doi:10.64898/2026.01.13.699211Cold Spring Harbor Laboratory Press2026-01-13
<![CDATA[
Spatial organization of mAbs in complex with the virus glycoprotein determines the success of intravenous rabies therapy
]]>
https://biorxiv.org/cgi/content/short/2026.01.13.699195v1?rss=1"
Kim, S.Coleon, A.Larrous, F.Kergoat, L.Mougari, S.Lannoy, J.Tiago, M.Hardy, D.Kornobis, E.Rey, F. A.Benigni, F.Corti, D.Bourhy, H.de Melo, G. D.2026-01-13doi:10.64898/2026.01.13.699195Cold Spring Harbor Laboratory Press2026-01-13
<![CDATA[
Pangenome graph augmentation from unassembled long reads
]]>
https://biorxiv.org/cgi/content/short/2025.02.07.637057v1?rss=1"
Denti, L.Bonizzoni, P.Brejova, B.Chikhi, R.Krannich, T.Vinar, T.Hormozdiari, F.2025-02-08doi:10.1101/2025.02.07.637057Cold Spring Harbor Laboratory Press2025-02-08
<![CDATA[
Antigenic landscape of rabies and related lyssaviruses revealed by cryo-EM
]]>
https://biorxiv.org/cgi/content/short/2026.01.14.699513v1?rss=1"
Callaway, H. M.Zyla, D. S.Hastie, K. M.Harkins, S. S.Kothalawalage, S.Samarasinghe, N.Flynn, A.Hariharan, C.Yin, J.Corti, D.Bouhry, H.Dessain, S. K.Saphire, E. O.2026-01-14doi:10.64898/2026.01.14.699513Cold Spring Harbor Laboratory Press2026-01-14
<![CDATA[
Insulated Outlier Chromosomes Drive Metabolic and Evolutionary Innovation in Minimal Eukaryotic Algae
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https://biorxiv.org/cgi/content/short/2025.04.21.649811v1?rss=1"
Valiadi, M.Harrison, K.Loe-Mie, Y.Williams, B. A. P.Ankrett, D.Smirnoff, N.Monier, A.2025-04-22doi:10.1101/2025.04.21.649811Cold Spring Harbor Laboratory Press2025-04-22
<![CDATA[
The FANCM-RMI1/2 complex promotes genomic instability and PARP inhibitor sensitivity in BRCA2-deficicient cells.
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https://biorxiv.org/cgi/content/short/2026.01.15.699681v1?rss=1"
Dossin, F.Attia, M.Zuniga, F. M.Acosta, D. G.Brough, R.Song, F. F.Bore, A.Margueron, R.Lopes, M.Lord, C. J.Deriano, L.2026-01-15doi:10.64898/2026.01.15.699681Cold Spring Harbor Laboratory Press2026-01-15
<![CDATA[
Taxonomic-free metagenome GWAS to identify gut microbiome functions influencing host phenotypes
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https://biorxiv.org/cgi/content/short/2026.01.15.699651v1?rss=1"
Malak, R.Frouin, A.Henches, L.Auvergne, A.Boetto, C.Milieu Interieur Consortium,Sokol, H.Chikhi, R.Aschard, H.2026-01-15doi:10.64898/2026.01.15.699651Cold Spring Harbor Laboratory Press2026-01-15
<![CDATA[
YraN is a helicase-associated nuclease fostering extended recombination events by natural transformation
]]>
https://biorxiv.org/cgi/content/short/2024.02.06.579203v1?rss=1"
Hardy, L.Plantade, J.Morales, V.Mazzamurro, F.Rocha, E. P. C.Polard, P.Charpentier, X.2024-02-06doi:10.1101/2024.02.06.579203Cold Spring Harbor Laboratory Press2024-02-06
<![CDATA[
High-quality proteins and RNAs extracted from exact same samples for proteomics and RNA-Seq analyses
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https://biorxiv.org/cgi/content/short/2026.01.16.699903v1?rss=1"
Fatou, M.Kornobis, E.Douche, T.Druart, K.Puchot, N.Matondo, M.Monot, M.Bourgouin, C.2026-01-19doi:10.64898/2026.01.16.699903Cold Spring Harbor Laboratory Press2026-01-19
<![CDATA[
Phylogenetic analysis of enteroviruses from non-human primates reveals two new species within the genus Enterovirus and inter-species recombination
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https://biorxiv.org/cgi/content/short/2026.01.19.700265v1?rss=1"
Aube, C.Cruz de Casa, P.Prot, M.Baidaliuk, A.Endegue Zanga, M. C.Simon-Loriere, E.Jouvenet, N.Sadeuh-Mba, S.Bessaud, M.2026-01-20doi:10.64898/2026.01.19.700265Cold Spring Harbor Laboratory Press2026-01-20
<![CDATA[
Spatiotemporal dynamics of β-lactam-resistant E. coli in young diseased calves in Wallonia, Belgium
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https://biorxiv.org/cgi/content/short/2026.01.21.700780v1?rss=1"
Guerin, V.Cabanel, N.Meijer, G. M. M. D.Royer, G.Mainil, J. G.Duprez, J.-N.Salmon, M.Thiry, D.Glaser, P.2026-01-21doi:10.64898/2026.01.21.700780Cold Spring Harbor Laboratory Press2026-01-21
<![CDATA[
Single-cell spatially resolved transcriptomic characterization of the developing mouse cochlea
]]>
https://biorxiv.org/cgi/content/short/2026.01.21.700589v1?rss=1"
Jean, P.Mechaussier, S.Singh-Estivalet, A.Trebeau, C.Gaudin, A.Barrio Cano, L.Lelli, A.Wong Jun Tai, F.Megharba, S.Schmutz, S.Loulizi, S.Novault, S.Hardy, D.Moraes-Cabe, C.Hasan, M.Petit, C.Etournay, R.Michalski, N.2026-01-21doi:10.64898/2026.01.21.700589Cold Spring Harbor Laboratory Press2026-01-21
<![CDATA[
An elementary model of homeostasis and immunity that generates symbiosis
]]>
https://biorxiv.org/cgi/content/short/2026.01.15.695950v1?rss=1"
Eberl, G.2026-01-22doi:10.64898/2026.01.15.695950Cold Spring Harbor Laboratory Press2026-01-22
<![CDATA[
IMAGENE: Single-cell association of live cell imaging and gene expression profiles of non-adherent cells through photoactivatable adhesives
]]>
https://biorxiv.org/cgi/content/short/2026.01.20.700510v1?rss=1"
Gariboldi, M. I.Sturmach, C.Bernard, S.Weber, C.Gourves, M.Umeda, Y.Li, X.Yamahira, S.Fernandes, J.Saez-Cirion, A.Yamaguchi, S.Muller, F.2026-01-22doi:10.64898/2026.01.20.700510Cold Spring Harbor Laboratory Press2026-01-22
<![CDATA[
Global analysis of trimeric autotransporters reveals phylogenetically restricted secretion mechanism adaptations
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https://biorxiv.org/cgi/content/short/2026.01.22.700529v1?rss=1"
DORISON, L.AUDRAIN, B.Chamorro-Rodriguez, S.GHIGO, J.-M.BELOIN, C.2026-01-22doi:10.64898/2026.01.22.700529Cold Spring Harbor Laboratory Press2026-01-22
<![CDATA[
Modelling multicellular coordination by bridging cell-cell communication and intracellular regulation through multilayer networks
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https://biorxiv.org/cgi/content/short/2026.01.20.700561v1?rss=1"
View larger version (34K):
org.highwire.dtl.DTLVardef@7cdceforg.highwire.dtl.DTLVardef@18cfa3eorg.highwire.dtl.DTLVardef@812645org.highwire.dtl.DTLVardef@f7bce5_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>Trimbour, R.Ramirez Flores, R. O.Saez-Rodriguez, J.Cantini, L.2026-01-22doi:10.64898/2026.01.20.700561Cold Spring Harbor Laboratory Press2026-01-22
<![CDATA[
Anopheles resistance to deltamethrin can be caused by the increased abundance of an enteric Aeromonas taxon
]]>
https://biorxiv.org/cgi/content/short/2026.01.23.701251v1?rss=1"
Nardini, L.Zakhia, R.Czarnecki, J.Brito-Fravallo, E.Geneve, C.Mavridis, K.Fricaux, T.Vontas, J.Vernick, K.Le Goff, G.Mitri, C.2026-01-23doi:10.64898/2026.01.23.701251Cold Spring Harbor Laboratory Press2026-01-23
<![CDATA[
Mechanism-Specific Speech Encoding Failures in Auditory Neuropathy: A Computational Phenotyping Framework
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https://biorxiv.org/cgi/content/short/2026.01.24.701491v1?rss=1"
Campi, M.Partouche, E.Gerenton, G.Avan, P.Gaultier, C.2026-01-25doi:10.64898/2026.01.24.701491Cold Spring Harbor Laboratory Press2026-01-25
<![CDATA[
Core-sheath coupling controls flagellar curvature and motility in Leptospira
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https://biorxiv.org/cgi/content/short/2026.02.02.703089v1?rss=1"
San Martin, F.Brady, M. R.Fule, L.Rodriguez, A.Mondino, S.Larrieux, N.Wunder, E. A.Ko, A. I.Rey, M.Chamot-Rooke, J.Duran, R.Trajtenberg, F.Picardeau, M.Sindelar, C. V.Buschiazzo, A.2026-02-02doi:10.64898/2026.02.02.703089Cold Spring Harbor Laboratory Press2026-02-02
<![CDATA[
Automated Optimization of Bacterial Tracking Pipelines with TrackMate 8
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https://biorxiv.org/cgi/content/short/2026.02.06.704368v1?rss=1"
Anselmet, M.Xenard, L.Albert, M.Arias-Cartin, R.Hicham, S.Pokorny, L.Paulet, E.Petit, J.Cutler, K. J.Gallusser, B.Weigert, M.Wehenkel, A.-M.Manina, G.Gomperts-Boneca, I.Barras, F.Bonazzi, D.Dumenil, G.Tinevez, J.-Y.2026-02-06doi:10.64898/2026.02.06.704368Cold Spring Harbor Laboratory Press2026-02-06
<![CDATA[
AncientMetagenomeDir dating metadataset highlights need for standardised radiocarbon reporting in ancient DNA
]]>
https://biorxiv.org/cgi/content/short/2026.02.06.704039v1?rss=1"
Hearne, K.Spurite, D.Hübner, A.Bonucci, B.Huang, Y.Bartholdy, B. P.Rozwalak, P.Becerra-Valdivia, L.Borry, M.Bozzi, D.Brativnyk, A.Brunt, J.Dagtas, N.de Dios, T.Ferguson, C. R.Frangenberg, J.Guinet, B.Haller-Caskie, M.Harder, R.Jackson, I.Jin, C.Keller, M.Kocher, A.Light-Maka, I.Lopopolo, M.Lutz, F.Michel, M.Nunes Yamunaque, D. J.Özdogan, K. T.Pochon, Z.Ponce-Soto, G. Y.Psonis, N.Ramirez, D. A.Richtermeier, T.Schreiber, L.Schumacher, M. L.Swali, P.Tran, C. N. H.Velsko, I. M.Warinner, C.White, A. E.Zampirolo, G.2026-02-06doi:10.64898/2026.02.06.704039Cold Spring Harbor Laboratory Press2026-02-06
<![CDATA[
A Multiplex Droplet Digital PCR Assay for Chromosome Copy Number Determination in Candida albicans
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https://biorxiv.org/cgi/content/short/2026.02.09.704919v1?rss=1"
Maciel, E. I.Ursuegui, S.Ahmed-Seghir, S.Maufrais, C.Roy, S.Gautier, C.Brandt, P.Jovelet, C.Pitayu, L.Ene, I. V.2026-02-10doi:10.64898/2026.02.09.704919Cold Spring Harbor Laboratory Press2026-02-10
<![CDATA[
Pneumococcus drives STAT3 activation of lower airway epithelium in a strain and burden-dependent manner
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https://biorxiv.org/cgi/content/short/2026.02.13.705726v1?rss=1"
Both, A.Chevalier, C.Connor, M. G.Hamon, M. A.2026-02-13doi:10.64898/2026.02.13.705726Cold Spring Harbor Laboratory Press2026-02-13
<![CDATA[
In vivo experimental model of β-glucan-induced innate immune memory
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https://biorxiv.org/cgi/content/short/2026.02.13.705736v1?rss=1"
View larger version (30K):
org.highwire.dtl.DTLVardef@d41c3aorg.highwire.dtl.DTLVardef@18939cdorg.highwire.dtl.DTLVardef@31e879org.highwire.dtl.DTLVardef@956f6b_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIPreparation of {beta}-glucan for in vivo experiments.
C_LIO_LIIn vivo modulation of innate immune memory through repeated intraperitoneal {beta}-glucan injections in mice.
C_LIO_LIModulation of innate immune memory is assessed by enhanced bone marrow hematopoiesis and GMP production.
C_LI
]]>Matvieieva, K.Wong, S. S. W.Bohm, M.Hassan, A.Quintin, J.2026-02-16doi:10.64898/2026.02.13.705736Cold Spring Harbor Laboratory Press2026-02-16
<![CDATA[
Evolutionary Advantage of Diversity-Generating Retroelements in Switching Environments
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https://biorxiv.org/cgi/content/short/2026.02.18.706561v1?rss=1"
Regnier, L.Rochette, P.Laurenceau, R.Bikard, D.Cocco, S.Monasson, R.2026-02-18doi:10.64898/2026.02.18.706561Cold Spring Harbor Laboratory Press2026-02-18
<![CDATA[
TMPRSS2 reduces antibody recognition of SARS-CoV-2 spike
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https://biorxiv.org/cgi/content/short/2026.02.17.706397v1?rss=1"
Cottignies-Calamarte, A.De Cruz, A.Planchais, C.Porrot, F.Krzypow, M.Jungbauer-Groznica, M.Thuillier, E.Wileveau, A.Staropoli, I.Guivel-Benhassine, F.Rosenbaum, P.Fernandez, I.Rey, F. A.Buchrieser, J.Trouillet-Assant, S.Mouquet, H.Schwartz, O.Bruel, T.2026-02-20doi:10.64898/2026.02.17.706397Cold Spring Harbor Laboratory Press2026-02-20
<![CDATA[
Hijacking of inflammasome responses by the complement system during Pseudomonas aeruginosa-Aspergillus fumigatus sur-infection
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https://biorxiv.org/cgi/content/short/2026.02.20.707105v1?rss=1"
Khau, S.Treps, L.Ilango, G.Riteau, N.Couillin, I.Togbe, D.Bigot, J.Balloy, V.David, C.Charrier Le Blan, M.Fouquenet, D.Vasseur, V.Fontaine, T.Pappworth, I.Marchbank, K.Paget, C.Baranek, T.Biquand, E.Britto, C. J.Guillot, L.Si-Tahar, M.Briard, B.2026-02-22doi:10.64898/2026.02.20.707105Cold Spring Harbor Laboratory Press2026-02-22
<![CDATA[
Deep learning extracts MoA-specific signatures from high-throughput images of chemically and genetically perturbed Corynebacteria
]]>
https://biorxiv.org/cgi/content/short/2026.02.23.707449v1?rss=1"
Krentzel, D.Petit, J.Boudehen, Y.-M.Mahtal, N.Sadowski, E.Zettor, A.Aubry, A.Chiaravalli, J.Aulner, N.Petrella, S.Alzari, P. M.Zimmer, C.Wehenkel, A. M.2026-02-23doi:10.64898/2026.02.23.707449Cold Spring Harbor Laboratory Press2026-02-23
<![CDATA[
The phylodynamic threshold of measurably evolving populations
]]>
https://biorxiv.org/cgi/content/short/2025.07.07.663495v1?rss=1"
Weber, A.Kende, J.Oeversti, S.Duchene, S.2025-07-08doi:10.1101/2025.07.07.663495Cold Spring Harbor Laboratory Press2025-07-08
<![CDATA[
A platform for high-throughput and ultrasensitive immunopeptidomics
]]>
https://biorxiv.org/cgi/content/short/2026.02.23.707388v1?rss=1"
Gul, A.Van Moortel, L.Willems, P.Aernout, I.Pedro-Cos, L.Ferrell, K. C.Boucher, K.Staes, A.Devos, S.Lentacker, I.Vandekerckhove, B.Demangel, C.Thery, F.Impens, F.2026-02-24doi:10.64898/2026.02.23.707388Cold Spring Harbor Laboratory Press2026-02-24
<![CDATA[
DNA-PK controls cyclic dinucleotide-associated type I Interferon responses
]]>
https://biorxiv.org/cgi/content/short/2024.09.17.613246v1?rss=1"
taffoni, c.vila, i. k.jardine, j.schussler, m.McKellar, J.Chemarin, M.Re, J.Messaout-Nacer, Y.El Mansouri, I.Chrousos, G. P.Bidere, N.Majzoub, K.Vlachakis, D.Laguette, N.2024-09-20doi:10.1101/2024.09.17.613246Cold Spring Harbor Laboratory Press2024-09-20
<![CDATA[
Multilocus microsatellite typing (MLMT) reveals high genetic diversity of Leishmania infantum strains causing tegumentary leishmaniasis in northern Italy
]]>
https://biorxiv.org/cgi/content/short/2026.02.24.707666v1?rss=1"
0.25). TL strains were divided into two main populations: one shared with VL-associated strains (PopB; 9/44) and a second population found exclusively among TL cases (PopC; 28/44). In contrast, the canine-associated population (PopA) showed no overlap with TL cases in this region. Populations also displayed divergent heterozygosity patterns, as indicated by positive and negative Fis values.
Conclusions/SignificanceThese findings revealed previously unknown diversity within L. infantum in the study area and demonstrated that inclusion of tegumentary strains is essential to uncover hidden components of parasite population structure. The identification of a TL-associated population supports the existence of multiple evolutionary pathways and emphasises the importance of integrated One Health surveillance, which combines data from humans, animal hosts and vectors to improve understanding of the epidemiology of leishmaniasis in Italy.
Author summaryLeishmania infantum is a parasite transmitted to humans through the bite of infected insect vectors. It can cause different forms of leishmaniasis, ranging from a systemic disease known as visceral leishmaniasis to a less common form that affects the skin and mucous membranes, called tegumentary leishmaniasis. Dogs are the main reservoir of the parasite and play a key role in maintaining its circulation in endemic areas. In recent years, cases of tegumentary leishmaniasis have re-emerged in northern Italy. This unexpected increase has raised questions about how the parasite is spreading and whether genetic differences among the parasites could explain these new patterns. To explore this, we examined parasitic DNA obtained from tegumentary leishmaniasis cases and compared it with DNA from patients with visceral leishmaniasis, from dogs and insect vectors from the same area. By examining multiple genetic markers, we found that parasites causing the tegumentary form of the disease are genetically diverse and belong to different groups. Notably, one parasite group was found only in cases of tegumentary leishmaniasis and not in visceral infections nor in infected dogs, suggesting that some parasite lineages may be more closely associated with skin and mucosal disease. Overall, our findings show that studying parasites from cutaneous and mucosal lesions provides important information that would otherwise remain hidden. By combining data from humans, animals and insect vectors, our study highlights the importance of integrated surveillance systems for improving our understanding of disease spread and supporting effective public health strategies.
]]>Rugna, G.Carra, E.Calzolari, M.Bergamini, F.Rabitti, A.Gritti, T.Ortalli, M.Lazzarotto, T.Gaspari, V.Castelli, G.Bruno, F.Späth, G. F.Varani, S.2026-02-25doi:10.64898/2026.02.24.707666Cold Spring Harbor Laboratory Press2026-02-25
<![CDATA[
Coupling metabolic enhancement to plasmid spread enables programmable antimicrobial control
]]>
https://biorxiv.org/cgi/content/short/2026.02.25.707879v1?rss=1"
Dorado Morales, P.Calvo-Villamanan, A.Audrain, B.Niedermeier, L.Lamberioux, M.Ducos-Galand, M.Stecher, B.Ghigo, J.-M.San Millan, A.Mazel, D.2026-02-25doi:10.64898/2026.02.25.707879Cold Spring Harbor Laboratory Press2026-02-25
<![CDATA[
Dynamic phosphoproteomics and proteomics uncover Leishmania donovani-driven ferritin hijacking, contributing to the control of iron homeostasis and iron-related oxidative stress
]]>
https://biorxiv.org/cgi/content/short/2026.02.25.707907v1?rss=1"
Shintre, S. S.Dingli, F.Meyerhoefer, N.Gorgette, O.Thouvenot, C.Blumenthal, D. B.Loew, D.Silvestre, A.RACHIDI, N.2026-02-25doi:10.64898/2026.02.25.707907Cold Spring Harbor Laboratory Press2026-02-25
<![CDATA[
A pocket-centric framework for selective targeting of amyloid fibril polymorphs
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https://biorxiv.org/cgi/content/short/2026.02.25.707901v1?rss=1"
Ossard, G.Ciambur, C. B.Melki, R.Sperandio, O.Romero, E.2026-02-26doi:10.64898/2026.02.25.707901Cold Spring Harbor Laboratory Press2026-02-26
<![CDATA[
Parallel evolution of industrial melanism in the peppered moth: one locus, many alleles
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https://biorxiv.org/cgi/content/short/2026.02.26.707722v1?rss=1"
Whiteford, I.Campagne, P.van't Hof, A. E.Yung, C. J.Berenbrink, M.Tian, S.Todd, F.Delf, J.Monteiro, A.Marec, F.Rakosy, L.Betancourt, A.SACCHERI, I. J.2026-02-26doi:10.64898/2026.02.26.707722Cold Spring Harbor Laboratory Press2026-02-26
<![CDATA[
Cross hybridization Inference for Phylogenetic Resolution (CIPHR)-FISH enables microbiome imaging with strain level taxonomic resolution
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https://biorxiv.org/cgi/content/short/2026.02.26.708344v1?rss=1"
Adade, E. E.Wang, R.Henneberry, C. M.Lemus, A. A.Stevick, R. J.Perez-Pascual, D.Audrain, B.Orsino, A. J.Farnsworth, D. R.Ghigo, J.-M.Valm, A. M.2026-02-27doi:10.64898/2026.02.26.708344Cold Spring Harbor Laboratory Press2026-02-27
<![CDATA[
Integrin beta 1 and mannose receptor 2 are involved in the antifungal activity of bronchial epithelial cells through Aspergillus fumigatus lectin FleA interactions
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https://biorxiv.org/cgi/content/short/2026.02.26.708144v1?rss=1"
Millet, N.Moreau, A.Tarizzo, M.Marti, L.Varrot, A.Gillon, E.Richard, N.Pionneau, C.Chardonnet, S.Varet, H.Morichon, R.Guitard, J.Guillot, L.Balloy, V.Bigot, J.2026-02-27doi:10.64898/2026.02.26.708144Cold Spring Harbor Laboratory Press2026-02-27
<![CDATA[
Rapid modular evolution of antiviral repertoires in P2 phages and their P4 satellites: shuttling, swapping and mixing
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https://biorxiv.org/cgi/content/short/2026.02.27.708500v1?rss=1"
Moura de Sousa, J.Depardieu, F.Touchon, M.Laurenceau, R.Curry, K.Maestri, A.Tesson, F.Lobat, A.Chikhi, R.Cury, J.Bernheim, A.Bikard, D.Rocha, E. P. C.2026-02-28doi:10.64898/2026.02.27.708500Cold Spring Harbor Laboratory Press2026-02-28
<![CDATA[
Modified Elek test improves in-vitro detection of diphtheria toxin
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https://biorxiv.org/cgi/content/short/2026.02.27.708555v1?rss=1"
Badell-Ocando, E.Bremont, S.Barbet, M.Passet, V.Crestani, C.Brisse, S.2026-03-01doi:10.64898/2026.02.27.708555Cold Spring Harbor Laboratory Press2026-03-01
<![CDATA[
Structure-guided generative design of peptides targeting the FtsQBL divisome complex inhibit Escherichia coli cell division.
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https://biorxiv.org/cgi/content/short/2026.02.27.708549v1?rss=1"
Remont, P.Liu, X.Croci, F.Mechaly, A.Karimova, G.Nguyen, M.-H.Guijarro, J. I.Davi, M.Guyon, C.Ciambur, C. B.Agou, F.Boucharlat, A.Ahmed, H.Chiaravalli, J.Ladant, D.Sperandio, O.2026-03-01doi:10.64898/2026.02.27.708549Cold Spring Harbor Laboratory Press2026-03-01
<![CDATA[
A crypt-operating DNA repair checkpoint for uncoupling regeneration and tumorigenesis
]]>
https://biorxiv.org/cgi/content/short/2026.02.27.708480v1?rss=1"
Ruez, R.Radulovic, K.Martinez-Torres, J.Boulard, O.Mound, A.Paz Del Socorro, T.Nigro, G.Seillier-Turini, M.Muharram, G.Martinez-Garcia, J.Gerbe, F.Van Seuningen, I.Carrier, A.Jay, P.Cochet, C.Vincent, A.Abbadie, C.Sobhani, I.Cochet, O.De Oliveira Alves, N.CHAMAILLARD, M.2026-03-02doi:10.64898/2026.02.27.708480Cold Spring Harbor Laboratory Press2026-03-02
<![CDATA[
Common γ-chain cytokines induce an epigenomically plastic precursor-like KIT+ ILC2 state linked to immune disease susceptibility
]]>
https://biorxiv.org/cgi/content/short/2026.02.27.708582v1?rss=1"
Olsthoorn, S. E. M.Onrust-Van Schoonhoven, A.de Bruijn, M. J. W.van Nimwegen, M.van Beek, G.de Koning, W.Trap, L.van der Ploeg, E. K.Sanders, M. A.Surace, L.Di Santo, J. P.Hendriks, R. W.Stadhouders, R.2026-03-02doi:10.64898/2026.02.27.708582Cold Spring Harbor Laboratory Press2026-03-02
<![CDATA[
GTA-5: A Unified Graph Transformer Framework for Ligands and Protein Binding Sites - Part I: Constructing the PDB Pocket and Ligand Space
]]>
https://biorxiv.org/cgi/content/short/2026.02.27.708634v1?rss=1"
Ciambur, B. C.Pageau, R.Sperandio, O.2026-03-02doi:10.64898/2026.02.27.708634Cold Spring Harbor Laboratory Press2026-03-02
<![CDATA[
The limits of Bayesian estimates of divergence times in measurably evolving populations
]]>
https://biorxiv.org/cgi/content/short/2026.02.28.708707v1?rss=1"
Ivanov, S.Fosse, S.dos reis, M.Duchene, S.2026-03-03doi:10.64898/2026.02.28.708707Cold Spring Harbor Laboratory Press2026-03-03
<![CDATA[
Structural basis of MfpD, a versatile pathogeny protein from the mfp conservon of Mycobacterium tuberculosis
]]>
https://biorxiv.org/cgi/content/short/2026.03.03.709265v1?rss=1"
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org.highwire.dtl.DTLVardef@77b2d2org.highwire.dtl.DTLVardef@7d1908org.highwire.dtl.DTLVardef@f66eeforg.highwire.dtl.DTLVardef@ed159c_HPS_FORMAT_FIGEXP M_FIG GRAPHICAL ABSTRACT
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]]>Gedeon, A.Micaletto, M.Megrian, D.Leroy, E. C.Barbier, E.Raynal, B.Haouz, A.Alzari, P. M.Mayer, C.Petrella, S.2026-03-03doi:10.64898/2026.03.03.709265Cold Spring Harbor Laboratory Press2026-03-03
<![CDATA[
ViroSeek: a viral detection pipeline for second-generation sequencing
]]>
https://biorxiv.org/cgi/content/short/2026.03.04.706323v1?rss=1"
Berger, A.Lefebvre, M. J. M.Dainat, J.Jiolle, D.Conclois, I.Talignani, L.Mastriani, E.Cornelie, S.Berthet, N.Paupy, C.2026-03-04doi:10.64898/2026.03.04.706323Cold Spring Harbor Laboratory Press2026-03-04
<![CDATA[
Dual blockade of LILRB1 and LILRB2 enhances antiviral immune responses in SIV infection
]]>
https://biorxiv.org/cgi/content/short/2026.03.03.709246v1?rss=1"
Meurisse, F.Coindre, S.Wijkhuisen, A.Marlin, R.Fournier Le Ray, L.Pons, J.Abi-Rached, L.Gallouet, A.-S.Relouzat, F.Gourves, M.Saez-Cirion, A.Arase, H.Zurawski, G.Zurawski, S.Bosquet, N.Le Grand, R.Simon, S.Lambotte, O.Favier, B.2026-03-05doi:10.64898/2026.03.03.709246Cold Spring Harbor Laboratory Press2026-03-05
<![CDATA[
Single-Cell Transcriptomic Signatures Enable Stratified Combination Therapy for Platinum-Resistant Ovarian Cancer
]]>
https://biorxiv.org/cgi/content/short/2026.03.04.709546v1?rss=1"
Gall Mas, L.Kleinmanns, K.Pirttikoski, A.Santarelli, M.Stangeland, G.Dai, J.Marin Falco, M.Fontaneda-Arenas, D.Doerr, C.Hautaniemi, S.Hynninen, J.McCormac, E.Wennerberg, K.Bjorge, L.Vähärautio, A.Schwikowski, B.2026-03-06doi:10.64898/2026.03.04.709546Cold Spring Harbor Laboratory Press2026-03-06
<![CDATA[
NK cell receptor repertoires evolve under increased constraint butare not more diverse in menstruating mammals
]]>
https://biorxiv.org/cgi/content/short/2026.03.05.709850v1?rss=1"
Lavergne, C.Daunesse, M.BERTHELOT, C.2026-03-06doi:10.64898/2026.03.05.709850Cold Spring Harbor Laboratory Press2026-03-06
<![CDATA[
The lysosomal glutamine transporter SLC38A7/SNAT7 modulates SAMHD1 antiviral activity and promotes HIV-1 production in human macrophages
]]>
https://biorxiv.org/cgi/content/short/2026.03.06.709337v1?rss=1"
Niedergang, F.Herit, F.Le Bury, G.Provot, Q.To-Puzenat, D.Haagen, J.Matozo de Souza, T.Dumas, A.Morel, M.Margottin-Goguet, F.Sagne, C.Saez-Cirion, A.2026-03-06doi:10.64898/2026.03.06.709337Cold Spring Harbor Laboratory Press2026-03-06
<![CDATA[
Nucleoid-binding protein RicO anchors replication origins to the membrane to ensure correct chromosome segregation in Staphylococcus aureus
]]>
https://biorxiv.org/cgi/content/short/2026.03.06.710092v1?rss=1"
Schaeper, S.Izquierdo-Martinez, A.Liao, Q.Brito, A. D.Sorg, M.Saraiva, B. M.Taib, N.Wang, X.Pinho, M. G.2026-03-06doi:10.64898/2026.03.06.710092Cold Spring Harbor Laboratory Press2026-03-06
<![CDATA[
Structural insights into the inactive state of the adhesion GPCR ADGRV1
]]>
https://biorxiv.org/cgi/content/short/2026.03.05.709805v1?rss=1"
Achat, Y.Prevost, M. S.Mechaly, A.Genera, M.Colcombet-Cazenave, B.Bezault, A.Winter, J.-M.Venien-Bryan, C.Raynal, B.Lafaye, P.England, P.Ayme, G.Bonomi, M.Prezeau, L.Wolff, N.2026-03-07doi:10.64898/2026.03.05.709805Cold Spring Harbor Laboratory Press2026-03-07
<![CDATA[
A general methodology for liver sinusoid fenestration analysis based on 3D electron microscopy data
]]>
https://biorxiv.org/cgi/content/short/2026.03.07.710307v1?rss=1"
Pohar, C.Rekik, Y.Phan, M. S.Gallet, B.Desroches-Castane, A.Chevallet, M.Tinevez, J.-Y.Tillet, E.Vigano, N.Jouneau, P.-H.Deniaud, A.2026-03-09doi:10.64898/2026.03.07.710307Cold Spring Harbor Laboratory Press2026-03-09
<![CDATA[
Topological Regulation of the Mammalian Genome by Positive DNA Supercoiling
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https://biorxiv.org/cgi/content/short/2026.03.10.710740v1?rss=1"
Singh, A. K.Altamirano-Pacheco, L.Taing, L.DUBOIS, A.Navarro, P.2026-03-10doi:10.64898/2026.03.10.710740Cold Spring Harbor Laboratory Press2026-03-10
<![CDATA[
Transient cytoskeletal anisotropy encodes short-term mechanical memory
]]>
https://biorxiv.org/cgi/content/short/2026.03.09.710573v1?rss=1"
Gomez-Cruz, C.Gelin, M.Pradeau-Phelut, L.Munoz-Barrutia, A.Etienne-Manneville, S.Garcia-Gonzalez, D.2026-03-11doi:10.64898/2026.03.09.710573Cold Spring Harbor Laboratory Press2026-03-11
<![CDATA[
Plasticity of squamous differentiation drives drug resistance in HNSCC
]]>
https://biorxiv.org/cgi/content/short/2026.03.09.710514v1?rss=1"
Sipila, K.Vietri Rudan, M.Bhosale, P.Matthew Blakeley, M.Ganier, C.Kennedy, R.Rognoni, E.Watt, F. M.2026-03-11doi:10.64898/2026.03.09.710514Cold Spring Harbor Laboratory Press2026-03-11
<![CDATA[
Benchmarking BEAGLE to find optimal parameters for BEAST X
]]>
https://biorxiv.org/cgi/content/short/2026.03.10.710534v1?rss=1"
Fosse, S.Duchene, S.Duitama Gonzalez, C.2026-03-12doi:10.64898/2026.03.10.710534Cold Spring Harbor Laboratory Press2026-03-12
<![CDATA[
An optonanobody for reversible photoactivation of recombinant and native α7 nicotinic
]]>
https://biorxiv.org/cgi/content/short/2026.03.10.710770v1?rss=1"
Vangelatou, M.Stenboltk, K.Bay, S.Medjebeur, K.Ayme, G.Lafaye, P.Blondel, a.Mourot, A.Corringer, P.-J.2026-03-12doi:10.64898/2026.03.10.710770Cold Spring Harbor Laboratory Press2026-03-12
<![CDATA[
Structural basis for continuous DNA-end protection during ligation of double-strand breaks in yeast Non-Homologous End-Joining
]]>
https://biorxiv.org/cgi/content/short/2026.03.12.711350v1?rss=1"
missoury, s.Tettaravou, C.Castelli, S.Pelletier, A.Morin, V.Varela, P. F.Ropars, V.Mattarocci, S.Legrand, P.Modesti, M.Marcand, S.Charbonnier, J.-B.Delarue, M.2026-03-12doi:10.64898/2026.03.12.711350Cold Spring Harbor Laboratory Press2026-03-12
<![CDATA[
Accounting for Defective Viral Genomes in viral consensus genome reconstruction, application to influenza virus
]]>
https://biorxiv.org/cgi/content/short/2026.03.11.711002v1?rss=1"
Da Silva, K.Naffakh, N.Rameix-Welti, M.-A.Lemoine, F.2026-03-12doi:10.64898/2026.03.11.711002Cold Spring Harbor Laboratory Press2026-03-12
<![CDATA[
CAR-MACROPHAGES ACTIVATE ANTI TUMOR T CELLS IN THE ABSENCE OF PHAGOCYTOSIS
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https://biorxiv.org/cgi/content/short/2026.03.11.710792v1?rss=1"
Feldmann, L.Vaysse, A.Lemaitre, F.Corre, B.ALONSO, R.VAGANAY, C.GUERIN, M. V.Garcia, Z.Bousso, P.GRANDJEAN, C.2026-03-12doi:10.64898/2026.03.11.710792Cold Spring Harbor Laboratory Press2026-03-12
<![CDATA[
3D printed titanium anodized effects on human gingival fibroblasts response and bacterial colonization: a dual approach
]]>
https://biorxiv.org/cgi/content/short/2026.03.11.711067v1?rss=1"
Lefort, L.Gilles, S.Chamorro-Rodriguez, S.Giorgi, M.-L.Petit, S.Asselin, A.BELOIN, C.Fournier, B.Crenn, M.-J.2026-03-13doi:10.64898/2026.03.11.711067Cold Spring Harbor Laboratory Press2026-03-13
<![CDATA[
A Seven-Protein Assembly Promotes Stability, Neutralisation and Secretion of the T7SSb LXG-effector TelE
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https://biorxiv.org/cgi/content/short/2026.03.12.711312v1?rss=1"
Agrawal, P.Gonet, A.Toko, D.Gorkisch, J.Raoux-barbot, D.du Merle, L.Bouscasse, E.Matondo, M.Mechaly, A.Keong Teh, W.Bezault, A.Chenal, A.Bellinzoni, M.Dramsi, S.Gubellini, F.2026-03-13doi:10.64898/2026.03.12.711312Cold Spring Harbor Laboratory Press2026-03-13
<![CDATA[
Stress-responsive Mycobacterium tuberculosis subpopulations manipulate macrophage polarization and can be targeted to limit inflammation
]]>
https://biorxiv.org/cgi/content/short/2026.03.13.711673v1?rss=1"
Pokorny, L.Singh, L. K.Gangneux, N.Pillon, M.Chica, C.Pietrosemoli, N.Perthame, E.Zavala Alvarado, J. C.Hebert, O.Rochais, C.Lecoutey, C.Lepailleur, A.Cimino, M.Kornobis, E.Albert, M.Tinevez, J.-Y.Bouscasse, E.Matondo, M.Lo, S.Julia, Z.Le Gac, S.Grall, N.Manina, G.2026-03-15doi:10.64898/2026.03.13.711673Cold Spring Harbor Laboratory Press2026-03-15
<![CDATA[
Free-Living Amoeba act as transient permissive hosts for Leptospira spp.
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https://biorxiv.org/cgi/content/short/2026.03.16.712017v1?rss=1"
Luga, A.Inizan, C.Meunier, E.Albon, A.Burtet-Sarramegna, V.Picardeau, M.Goarant, C.Thibeaux, R.2026-03-16doi:10.64898/2026.03.16.712017Cold Spring Harbor Laboratory Press2026-03-16
<![CDATA[
Oscillatory Hedgehog signaling and temporal coordination of atonal dynamics at the eye differentiation front in Drosophila
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https://biorxiv.org/cgi/content/short/2026.03.16.712009v1?rss=1"
Phan, M.-S.Mestdagh, C.Schweisguth, F.2026-03-17doi:10.64898/2026.03.16.712009Cold Spring Harbor Laboratory Press2026-03-17
<![CDATA[
A NAPE-LRRK2 metabolic axis controls lysosomal homeostasis in Parkinson's disease
]]>
https://biorxiv.org/cgi/content/short/2026.03.19.712902v1?rss=1"
Palese, F.Giachino, C.Syan, S.Ottonello, G.Sciandrone, G.Filipponi, C.Lai, M.Armirotti, A.Deleidi, M.Zurzolo, C.2026-03-21doi:10.64898/2026.03.19.712902Cold Spring Harbor Laboratory Press2026-03-21
<![CDATA[
Synaptic dynamics as a tunable substrate shaping neuronal activity sequences
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https://biorxiv.org/cgi/content/short/2026.03.22.713064v1?rss=1"
Bender, F.Sermet, B. S.Borda Bossana, S.Barri, A.Schamiloglu, S.Diana, G.Costreie, M.Moneron, G.Hantman, A. W.DiGregorio, D. A.2026-03-23doi:10.64898/2026.03.22.713064Cold Spring Harbor Laboratory Press2026-03-23
<![CDATA[
Evolution of the genetic architecture of uterine disorders
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https://biorxiv.org/cgi/content/short/2026.03.24.713926v1?rss=1"
Liorzou, E.Julienne, H.Daunesse, M.Laval, G.Aschard, H.Berthelot, C.2026-03-25doi:10.64898/2026.03.24.713926Cold Spring Harbor Laboratory Press2026-03-25
<![CDATA[
MaRNAV-1 infection of Plasmodium vivax is associated with increased parasite transmission and host inflammatory responses
]]>
https://biorxiv.org/cgi/content/short/2026.03.22.713337v1?rss=1"
Seng, D.Ko, K.Orban, A.Heng, S.Feufack-Donfack, L.Tebben, K.Dumetz, F.Grunebast, J.Vignolini, T.Dore, G.Khim, N.Salvador, J.Ouaid, Z.Lefevre, T.Cohuet, A.Sommen, C.Flamand, C.Ruberto, A.Abebe, A.Tsigie, M.Malleret, B.Shenkutie, T.Lo, E.Cantaert, T.Anstey, N.Petrone, M.Baumgarten, S.Serre, D.Popovici, J.2026-03-25doi:10.64898/2026.03.22.713337Cold Spring Harbor Laboratory Press2026-03-25
<![CDATA[
Lytic bacteriophages active in urine against multi-drug resistant clinically derived Klebsiella pneumoniae causing urinary tract infection
]]>
https://biorxiv.org/cgi/content/short/2026.03.23.713486v1?rss=1"
Calin, R.Bernabeu Vilaplana, B.Gedeon, J.Capton, E.Galinat, C.Saffarian, A.Pierrat, G.Benzerara, Y.Wurtzer, S.Moulin, L.Eckert, C.Tournebize, R.2026-03-25doi:10.64898/2026.03.23.713486Cold Spring Harbor Laboratory Press2026-03-25
<![CDATA[
Homozygosity for rare or common hypomorphic IL23R variants confers a predisposition to tuberculosis in humans
]]>
https://biorxiv.org/cgi/content/short/2026.03.23.713554v1?rss=1"
Olguin Calderon, D.Kilpatrick, L. E.Conil, C.Philippot, Q.Ogishi, M.Vellutini, J.Eun Han, J.Keating, N.Li, H.Rao, G.Bohlen, J.Lay, C. S.Platt, S.Kerner, G.Feredj, E.Peel, J.Momenilandi, M.Seeleuthner, Y.Laine, C.soudee, c.Leloup, C.Debuisson, C.Lanternier, F.Bitoun, S. B.Pavy, S.Mariette, X.Rafik, A.Skhoun, H.EL Ouazzani, H.Abderahmani-Ghorfi, I.EL Baghdadi, J.Baena, A.Tejada-Giraldo, M.Barrera, L. F.Arias, A. A.Fabio, G.Carrabba, M.Emiroglu, M.Bezrodnik, L.EL Zein, L.Hammoud, H.Gregersen, P.Terrier, B.Leon L2026-03-25doi:10.64898/2026.03.23.713554Cold Spring Harbor Laboratory Press2026-03-25
<![CDATA[
Characterization of emerging Oropouche virus tropism and pathogenicity.
]]>
https://biorxiv.org/cgi/content/short/2026.03.25.714204v1?rss=1"
Bruant, H.Jeannin, P.Geolier, V.Mouly, V.Perthame, E.Mahtal, N.Pascard, J.Piumi, F.Rousset, D.CECCALDI, P.-E.Coulpier, M.Choumet, V.2026-03-25doi:10.64898/2026.03.25.714204Cold Spring Harbor Laboratory Press2026-03-25
<![CDATA[
EpiCure (Epithelial Curation): a versatile and handy tool for curation of epithelial segmentation
]]>
https://biorxiv.org/cgi/content/short/2026.03.27.714683v1?rss=1"
Letort, G.Valon, L.Michaut, A.Cumming, T.Xenard, L.Phan, M.-S.Dray, N.Rueden, C. T.Schweisguth, F.Gros, J.Bally-Cuif, L.Tinevez, J.-Y.Levayer, R.2026-03-27doi:10.64898/2026.03.27.714683Cold Spring Harbor Laboratory Press2026-03-27
<![CDATA[
Generative model of SARS-CoV-2 variants under functional and immune pressure unveils viral escape potential and antibody resilience
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https://biorxiv.org/cgi/content/short/2025.05.12.653592v1?rss=1"
Huot, M.Rosenbaum, P.Planchais, C.Mouquet, H.Monasson, R.Cocco, S.2025-05-13doi:10.1101/2025.05.12.653592Cold Spring Harbor Laboratory Press2025-05-13
<![CDATA[
Positional cues, not Notch, direct Neuroblast selection during early neurogenesis in the Drosophila embryo
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https://biorxiv.org/cgi/content/short/2026.03.30.715196v1?rss=1"
Green, D.Mazouni, K.Nos, M.Schweisguth, F.2026-04-01doi:10.64898/2026.03.30.715196Cold Spring Harbor Laboratory Press2026-04-01
<![CDATA[
Structure and dynamics of a multidomain ligand-gated ion channel revealed under acidic conditions
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https://biorxiv.org/cgi/content/short/2025.02.27.640520v1?rss=1"
Anden, O.Rovsnik, U.Lycksell, M.Delarue, M.Howard, R. J.Lindahl, E.2025-02-27doi:10.1101/2025.02.27.640520Cold Spring Harbor Laboratory Press2025-02-27
<![CDATA[
Contextual Prediction Tunes the Tempo of Speech Segmentation
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https://biorxiv.org/cgi/content/short/2026.03.31.713600v1?rss=1"
Platonova, O.Dogonasheva, O.Giraud, A.-L.Bouton, S.2026-04-02doi:10.64898/2026.03.31.713600Cold Spring Harbor Laboratory Press2026-04-02
<![CDATA[
Unveiling a missing component of the atypical type IV secretion system required for natural transformation of Helicobacter pylori
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https://biorxiv.org/cgi/content/short/2026.04.01.715814v1?rss=1"
Villa, J. F.Kondekar, S.Fauconnet, Y.Machouri, M.Lacrouts, C.Veaute, X.Guerois, R.Rocha, E. P. C.Andreani, J.Radicella, J. P.2026-04-02doi:10.64898/2026.04.01.715814Cold Spring Harbor Laboratory Press2026-04-02
<![CDATA[
Shared and distinct oscillatory fingerprints underlying episodic memory and word retrieval
]]>
https://biorxiv.org/cgi/content/short/2026.04.01.715566v1?rss=1"
Westner, B. U.Luo, Y.Piai, V.2026-04-03doi:10.64898/2026.04.01.715566Cold Spring Harbor Laboratory Press2026-04-03