bioRxiv Channel: NHGRI MorPhiC
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This feed contains articles for bioRxiv Channel "NHGRI MorPhiC"
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bioRxiv
https://biorxiv.org
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Leveraging CRISPR activation for rapid assessment of gene editing products in human pluripotent stem cells
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https://biorxiv.org/cgi/content/short/2024.09.29.615716v1?rss=1"
Wu, Y.
Zhong, A.
Evangelisti, A.
Sidharta, M.
Studer, L.
Zhou, T.
2024-09-30
doi:10.1101/2024.09.29.615716
Cold Spring Harbor Laboratory Press
2024-09-30
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Parallel genome-scale CRISPR screens distinguish pluripotency and self-renewal
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https://biorxiv.org/cgi/content/short/2023.05.03.539283v1?rss=1"
Rosen, B. P.
Li, Q. V.
Cho, H.
Liu, D.
Yang, D.
Graff, S.
Yan, J.
Luo, R.
Verma, N.
Damodaran, J. R.
Beer, M. A.
Sidoli, S.
Huangfu, D.
2023-05-03
doi:10.1101/2023.05.03.539283
Cold Spring Harbor Laboratory Press
2023-05-03
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Decoding Heterogenous Single-cell Perturbation Responses
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https://biorxiv.org/cgi/content/short/2023.10.30.564796v1?rss=1"
Song, B.
Liu, D.
Dai, W.
McMyn, N.
Wang, Q.
Yang, D.
Krejci, A.
Vasilyev, A.
Untermoser, N.
Loregger, A.
Song, D.
Williams, B.
Rosen, B.
Cheng, X.
Chao, L.
Kale, H.
Zhang, H.
Diao, Y.
Bürckstümmer, T.
Siliciano, J. M.
Li, J. J.
Siliciano, R.
Huangfu, D.
Li, W.
2023-11-02
doi:10.1101/2023.10.30.564796
Cold Spring Harbor Laboratory Press
2023-11-02
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Supervised Deep Learning with Gene Annotation for Cell Classification
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https://biorxiv.org/cgi/content/short/2024.07.15.603527v1?rss=1"
Lin, Z.
Sun, W.
2024-07-15
doi:10.1101/2024.07.15.603527
Cold Spring Harbor Laboratory Press
2024-07-15
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Singe cell RNA sequencing data processing using cloud-based serverless computing
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https://biorxiv.org/cgi/content/short/2025.04.26.650787v1?rss=1"
Hung, L.-H.
Nasam, N.
Lloyd, W.
Yeung, K. Y.
2025-04-30
doi:10.1101/2025.04.26.650787
Cold Spring Harbor Laboratory Press
2025-04-30
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Graphical and Interactive Spatial Proteomics Image Analysis Workflow
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https://biorxiv.org/cgi/content/short/2025.05.23.655879v1?rss=1"
Singh, P.
Wright, J. H.
Smythe, K. S.
Fukuda, B. N.
Hung, L.-H.
Yeung, C. C.
Yeung, K. Y.
2025-05-27
doi:10.1101/2025.05.23.655879
Cold Spring Harbor Laboratory Press
2025-05-27
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A stem cell knockout village reveals lineage rewiring and a non-canonical islet cell fate in monogenic diabetes
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https://biorxiv.org/cgi/content/short/2025.12.23.696311v1?rss=1"
Liu, D.
Song, B.
Li, Z.
Zhang, S.
Fabiha, T.
Zhao, J.
Inoki, A.
Piccand, J.
Soh, C.-L.
Dixon, G.
Zhong, A.
Hu, N.
Luo, R.
Ozlusen, B.
Menon, V.
Zhou, T.
Qiu, X.
Gradwohl, G.
Yang, D.
Dey, K.
Sun, W.
Li, W.
Huangfu, D.
2025-12-25
doi:10.64898/2025.12.23.696311
Cold Spring Harbor Laboratory Press
2025-12-25
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User-friendly scheduler Using a hybrid architecture and supercomputing for big data processing
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https://biorxiv.org/cgi/content/short/2025.09.01.673517v1?rss=1"
McKeever, P.
Mittal, V.
Fukuda, B.
Yeung, K. Y.
Hung, L.-H.
2025-09-03
doi:10.1101/2025.09.01.673517
Cold Spring Harbor Laboratory Press
2025-09-03
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STAR Suite: Integrating transcriptomics through AI software engineering in the NIH MorPhiC consortium
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https://biorxiv.org/cgi/content/short/2026.03.09.710580v1?rss=1"
Hung, L.-H.
Yeung, K. Y.
2026-03-10
doi:10.64898/2026.03.09.710580
Cold Spring Harbor Laboratory Press
2026-03-10
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Human Dicer1 hotspot mutation induces both loss and gain of miRNA function
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https://biorxiv.org/cgi/content/short/2025.10.15.682667v1?rss=1"
Jee, D.
Lee, S.
Yang, D.
Rickert, R.
Shang, R.
Huangfu, D.
Lai, E. C.
2025-10-15
doi:10.1101/2025.10.15.682667
Cold Spring Harbor Laboratory Press
2025-10-15
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Common data models to streamline metabolomics processing and annotation, and implementation in a Python pipeline
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https://biorxiv.org/cgi/content/short/2024.02.13.580048v1?rss=1"
Mitchell, J.
Chi, Y.
Thapa, M.
Pang, Z.
Xia, J.
Li, S.
2024-02-14
doi:10.1101/2024.02.13.580048
Cold Spring Harbor Laboratory Press
2024-02-14