bioRxiv Channel: SeroNet
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https://biorxiv.org
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SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo
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https://biorxiv.org/cgi/content/short/2020.09.28.317685v1?rss=1"
Hou, Y. J.Chiba, S.Halfmann, P.Ehre, C.Kuroda, M.Dinnon, K. H.Leist, S. R.Schäfer, A.Nakajima, N.Takahashi, K.Lee, R. E.Mascenik, T. M.Edwards, C. E.Tse, L. V.Boucher, R. C.Randell, S. H.Suzuki, T.Gralinski, L. E.Kawaoka, Y.Baric, R. S.2020-09-29doi:10.1101/2020.09.28.317685Cold Spring Harbor Laboratory Press2020-09-29
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An Engineered Antibody with Broad Protective Efficacy in Murine Models of SARS and COVID-19
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https://biorxiv.org/cgi/content/short/2020.11.17.385500v1?rss=1"
Rappazzo, C. G.Tse, L. V.Kaku, C. I.Wrapp, D.Sakharkar, M.Huang, D.Deveau, L. M.Yockachonis, T. J.Herbert, A. S.Battles, M. B.O'Brien, C. M.Brown, M. E.Geoghegan, J. C.Belk, J.Peng, L.Yang, L.Scobey, T. D.Burton, D. R.Nemazee, D.Dye, J. M.Voss, J. E.Gunn, B. M.McLellan, J. S.Baric, R. S.Gralinski, L. E.Walker, L. M.2020-11-17doi:10.1101/2020.11.17.385500Cold Spring Harbor Laboratory Press2020-11-17
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Immunological memory to SARS-CoV-2 assessed for greater than six months after infection
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https://biorxiv.org/cgi/content/short/2020.11.15.383323v1?rss=1"
Dan, J. M.Mateus, J.Kato, Y.Hastie, K. M.Faliti, C.Ramirez, S. I.Frazier, A.Yu, E. D.Grifoni, A.Rawlings, S. A.Peters, B.Krammer, F.Simon, V.Saphire, E. O.Smith, D.Weiskopf, D.Sette, A.Crotty, S.2020-11-16doi:10.1101/2020.11.15.383323Cold Spring Harbor Laboratory Press2020-11-16
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Host-directed therapies against early-lineage SARS-CoV-2 retain efficacy against B.1.1.7 variant
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https://biorxiv.org/cgi/content/short/2021.01.24.427991v1?rss=1"
Reuschl, A.-K.Thorne, L.Zuliani Alvarez, L.Bouhaddou, M.Obernier, K.Soucheray, M.Turner, J.Fabius, J.Nguyen, G. T.Swaney, D.Rosales, R.White, K. M.Aviles, P.Kirby, I. T.Melnyk, J. E.Shi, Y.Zhang, Z.Shokat, K.Garcia-Sastre, A.Jolly, C.Towers, G. J.Krogan, N. J.2021-01-24doi:10.1101/2021.01.24.427991Cold Spring Harbor Laboratory Press2021-01-24
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Collaboration between the Fab and Fc contribute to maximal protection against SARS-CoV-2 in nonhuman primates following NVX-CoV2373 subunit vaccine with Matrix-M™ vaccination
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https://biorxiv.org/cgi/content/short/2021.02.05.429759v1?rss=1"
Gorman, M. J.Patel, N.Guebre-Xabier, M.Zhu, A.Atyeo, C.Pullen, K.Loos, C.Goez-Gazi, Y.Carrion, R.Tian, J.-H.Yuan, D.Bowman, K.Zhou, B.Maciejewski, S.McGrath, M.Logue, J.Frieman, M.Montefiori, D.Mann, C.Schendel, S.Amanat, F.Krammer, F.Saphire, E. O.Lauffenburger, D. A.Greene, A. M.Portnoff, A. D.Massare, M. J.Ellingsworth, L.Glenn, G.Smith, G.Alter, G.2021-02-05doi:10.1101/2021.02.05.429759Cold Spring Harbor Laboratory Press2021-02-05
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Integrated plasma proteomic and single-cell immune signaling network signatures demarcate mild, moderate, and severe COVID-19
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https://biorxiv.org/cgi/content/short/2021.02.09.430269v1?rss=1"
Feyaerts, D.Hedou, J.Gillard, J.Chen, H.Tsai, E. S.Peterson, L. S.Ando, K.Manohar, M.Do, E.Dhondalay, G. K. R.Fitzpatrick, J.Artandi, M.Chang, I.Snow, T. T.Chinthrajah, R. S.Warren, C. M.Wittman, R.Meyerowitz, J. G.Ganio, E. A.Stelzer, I. A.Han, X.Verdonk, F.Gaudilliere, D. K.Mukherjee, N.Tsai, A. S.Rumer, K. K.Jiang, S. J.Valdes-Ferrer, S. I.Kelly, J. D.Furman, D.Aghaeepour, N.Angst, M. S.Boyd, S. D.Pinsky, B. A.Nolan, G. P.Nadeau, K. C.Gaudilliere, B.McIlwain, D. R.2021-02-12doi:10.1101/2021.02.09.430269Cold Spring Harbor Laboratory Press2021-02-12
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Negligible impact of SARS-CoV-2 variants on CD4+ and CD8+ T cell reactivity in COVID-19 exposed donors and vaccinees.
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https://biorxiv.org/cgi/content/short/2021.02.27.433180v1?rss=1"
Tarke, A.Sidney, J.Methot, N.Zhang, Y.Dan, J. M.Goodwin, B.Rubiro, P.Sutherland, A.da Silva Antunes, R.Fraizer, A.Rawlings, S. A.Smith, D. M.Peters, B.Scheuermann, R. H.Weiskopf, D.Crotty, S.Grifoni, A.Sette, A.2021-03-01doi:10.1101/2021.02.27.433180Cold Spring Harbor Laboratory Press2021-03-01
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Chimeric spike mRNA vaccines protect against sarbecovirus challenge in mice
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https://biorxiv.org/cgi/content/short/2021.03.11.434872v1?rss=1"
Martinez, D. R.Schaefer, A.Leist, S. R.De la Cruz, G.West, A.Atochina-Vasserman, E. N.Parks, R.Barr, M.Li, D.Yount, B.Saunders, K. O.Weissman, D.Haynes, B.Montgomery, S. A.Baric, R. S.2021-03-12doi:10.1101/2021.03.11.434872Cold Spring Harbor Laboratory Press2021-03-12
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A broadly neutralizing antibody protects against SARS-CoV, pre-emergent bat CoVs, and SARS-CoV-2 variants in mice
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https://biorxiv.org/cgi/content/short/2021.04.27.441655v1?rss=1"
Martinez, D.Schaefer, A.Gobeil, S.Li, D.De la Cruz, G.Parks, R.Lu, X.Barr, M.Manne, K.Mansouri, K.Edwards, R. J.Yount, B.Anasti, K.Montgomery, S.Shen, X.Zhou, T.Kwong, P.Graham, B.Mascola, J. R.Montefiori, D.Alam, M.Sempowski, G.Wiehe, K.Saunders, K. O.Acharya, P.Haynes, B.Baric, R. S.2021-04-28doi:10.1101/2021.04.27.441655Cold Spring Harbor Laboratory Press2021-04-28
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Early cross-coronavirus reactive signatures of protective humoral immunity against COVID-19
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https://biorxiv.org/cgi/content/short/2021.05.11.443609v1?rss=1"
Kaplonek, P.Wang, C.Bartsch, Y.Fischinger, S.Gorman, M. J.Bowman, K.Kang, J.Dayal, D.Martin, P.Nowak, R.Hsieh, C.-L.Feldman, J.Juelg, B.Nilles, E.Musk, E. R.Menon, A. S.Fischer, E. S.McLellan, J. S.Schmidt, A.Goldberg, M. B.Filbin, M.Hacohen, N.Lauffenburger, D. A.Alter, G.2021-05-12doi:10.1101/2021.05.11.443609Cold Spring Harbor Laboratory Press2021-05-12
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SARS-CoV-2 Spreads through Cell-to-Cell Transmission
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https://biorxiv.org/cgi/content/short/2021.06.01.446579v1?rss=1"
Zeng, C.Evans, J. P.King, T.Zheng, Y.-M.Oltz, E. M.Whelan, S. P. J.Saif, L.Peeples, M. E.Liu, S.-L.2021-06-01doi:10.1101/2021.06.01.446579Cold Spring Harbor Laboratory Press2021-06-01
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Evolution of enhanced innate immune evasion by the SARS-CoV-2 B.1.1.7 UK variant
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https://biorxiv.org/cgi/content/short/2021.06.06.446826v1?rss=1"
Thorne, L. G.Bouhaddou, M.Reuschl, A.-K.Zuliani-Alvarez, L.Polacco, B. J.Pelin, A.Batra, J.Whelan, M. V. X.Ummadi, M.Roic, A.Turner, J.Obernier, K.Braberg, H.Soucheray, M.Richards, A. L.Chen, K.-H.Harjai, B.Memon, D.Hosmillo, M.Hiatt, J.Jahun, A. S.Goodfellow, I. G.Noursadeghi, M.Fabius, J.Shokat, K.Jura, N.Verba, K. A.Beltrao, P.Swaney, D. L.Garcia-Sastre, A.Jolly, C.Towers, G. J.Krogan, N. J.2021-06-07doi:10.1101/2021.06.06.446826Cold Spring Harbor Laboratory Press2021-06-07
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Protective efficacy of rhesus adenovirus COVID-19 vaccines against mouse-adapted SARS-CoV-2
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https://biorxiv.org/cgi/content/short/2021.06.14.448461v1?rss=1"
Tostanoski, L.Gralinski, L.Martinez, D.Schaefer, A.Mahrokhian, S.Li, Z.Nampanya, F.Wan, H.Yu, J.Chang, A.Liu, J.McMahan, K.Dinnon, K.Leist, S. R.Baric, R. S.Barouch, D. H.2021-06-15doi:10.1101/2021.06.14.448461Cold Spring Harbor Laboratory Press2021-06-15
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Phosphatidylserine Receptors Enhance SARS-CoV-2 Infection: AXL as a Therapeutic Target for COVID-19
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https://biorxiv.org/cgi/content/short/2021.06.15.448419v1?rss=1"
Bohan, D.Van Ert, H.Ruggio, N.Rogers, K. J.Baddredine, M.Briseno, J. A. A.Rojas Chavez, R. A.Gao, B.Stokowy, T.Christakou, E.Micklem, D.Gausdal, G.Haim, H.Minna, J.Lorens, J. B.Maury, W.2021-06-15doi:10.1101/2021.06.15.448419Cold Spring Harbor Laboratory Press2021-06-15
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Subtle immunological differences in mRNA-1273 and BNT162b2 COVID-19 vaccine induced Fc-functional profiles
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https://biorxiv.org/cgi/content/short/2021.08.31.458247v1?rss=1"
Kaplonek, P.Cizmeci, D.Fischinger, S.Collier, A.-r.Suscovich, T.Linde, C.Broge, T.Mann, C.Amanat, F.Dayal, D.Rhee, J.de St. Aubin, M.Nilles, E. J.Musk, E. R.Menon, A. S.Ollmann Saphire, E.Krammer, F.Lauffenburger, D. A.Barouch, D. H.Alter, G.2021-08-31doi:10.1101/2021.08.31.458247Cold Spring Harbor Laboratory Press2021-08-31
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mRNA Vaccines Induce Rapid Antibody Responses in Mice
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https://biorxiv.org/cgi/content/short/2021.11.01.466863v1?rss=1"
Gebre, M.Rauch, S.Roth, N.Gergen, J.Yu, J.Liu, X.Cole, A.Mueller, S.Petsch, B. W.Barouch, D. H.2021-11-02doi:10.1101/2021.11.01.466863Cold Spring Harbor Laboratory Press2021-11-02
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Loss of Neutralizing Antibody Response to mRNA Vaccination against SARS-CoV-2 Variants: Differing Kinetics and Strong Boosting by Breakthrough Infection
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https://biorxiv.org/cgi/content/short/2021.12.06.471455v1?rss=1"
Evans, J. P.Zeng, C.Carlin, C.Lozanski, G.Saif, L. J.Oltz, E. M.Gumina, R. J.Liu, S.-L.2021-12-07doi:10.1101/2021.12.06.471455Cold Spring Harbor Laboratory Press2021-12-07
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Vaccine Protection Against the SARS-CoV-2 Omicron Variant in Macaques
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https://biorxiv.org/cgi/content/short/2022.02.06.479285v1?rss=1"
Chandrashekar, A.Yu, J.McMahan, K.Jacob-Dolan, C.Liu, J.He, X.Hope, D.Anioke, T.Barrett, J.Chung, B.Hachmann, N.Lifton, M.Miller, J.Powers, O.Sciacca, M.Sellers, D.Siamatu, M.Surve, N.VanWyk, H.Wan, H.Wu, C.Pessaint, L.Valentin, D.Van Ry, A.Muench, J.Boursiquot, M.Cook, A.Velasco, J.Teow, E.Boon, A.Suthar, M.Jain, N.Martinot, A. J.Lewis, M. G.Andersen, H.Barouch, D. H.2022-02-07doi:10.1101/2022.02.06.479285Cold Spring Harbor Laboratory Press2022-02-07
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Omicron BA.1 and BA.2 neutralizing activity elicited by a comprehensive panel of human vaccines
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https://biorxiv.org/cgi/content/short/2022.03.15.484542v1?rss=1"
Bowen, J. E.Sprouse, K. R.Walls, A. C.Mazzitelli, I. G.Logue, J. K.Franko, N. M.Ahmed, K.Shariq, A.Cameroni, E.Gori, A.Bori, A.Posavad, C. M.Dan, J. M.Zhang, Z.Weiskopf, D.Sette, A.Crotty, S.Talat Iqbal, N.Corti, D.Geffner, J.Grifantini, R.Chu, H. Y.Veesler, D.2022-03-16doi:10.1101/2022.03.15.484542Cold Spring Harbor Laboratory Press2022-03-16
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Comprehensive antibody profiling of mRNA vaccination in children
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https://biorxiv.org/cgi/content/short/2021.10.07.463592v1?rss=1"
Bartsch, Y. C.St Denis, K. J.Kaplonek, P.Kang, J.Lam, E. C.Farkas, E. J.Davis, J.Boribong, B.Shreffler, W.Balazs, A. B.Yonker, L. M.Galit, A.2021-10-09doi:10.1101/2021.10.07.463592Cold Spring Harbor Laboratory Press2021-10-09
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Immunological memory to Common Cold Coronaviruses assessed longitudinally over a three-year period
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https://biorxiv.org/cgi/content/short/2022.03.01.482548v1?rss=1"
Dawen, E.Narowski, T. M.Wang, E.Garrigan, E.Mateus, J.Frazier, A.Weiskopf, D.Grifoni, A.Premkumar, L.Sette, A.da Silva Antunes, R.2022-03-02doi:10.1101/2022.03.01.482548Cold Spring Harbor Laboratory Press2022-03-02
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Broadly neutralizing anti-S2 antibodies protect against all three human betacoronaviruses that cause severe disease
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https://biorxiv.org/cgi/content/short/2022.03.04.479488v1?rss=1"
Zhou, P.Song, G.He, W.-t.Beutler, N.Tse, L. V.Martinez, D. R.Schafer, A.Anzanello, F.Yong, P.Peng, L.Dueker, K.Musharrafieh, R.Callaghan, S.Capozzola, T.Yuan, M.Liu, H.Limbo, O.Parren, M.Garcia, E.Rawlings, S. A.Smith, D. M.Nemazee, D.Jardine, J. G.Wilson, I. A.Safonova, Y.Rogers, T.Baric, R. S.Gralinski, L. E.Burton, D. R.Andrabi, R.2022-03-07doi:10.1101/2022.03.04.479488Cold Spring Harbor Laboratory Press2022-03-07
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Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation
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https://biorxiv.org/cgi/content/short/2022.03.15.484018v1?rss=1"
Singh, A. K.Wang, R.Lombardo, K. A.Praharaj, M.Bullen, C. K.Um, P.Davis, S.Komm, O.Illei, P. B.Ordonez, A. A.Bahr, M.Huang, J.Gupta, A.Psoter, K. J.Jain, S. K.Bivalacqua, T. J.Yegnasubramanian, S.Bishai, W.2022-03-15doi:10.1101/2022.03.15.484018Cold Spring Harbor Laboratory Press2022-03-15
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A model of persistent post SARS-CoV-2 induced lung disease for target identification and testing of therapeutic strategies
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https://biorxiv.org/cgi/content/short/2022.02.15.480515v1?rss=1"
Dinnon, K. H.Leist, S. R.Okuda, K.Dang, H.Fritch, E. J.Gully, K. L.Cruz, G.Evangelista, M. D.Asakura, T.Gilmore, R. C.Hawkins, P.Nakano, S.West, A.Schäfer, A.Gralinski, L. E.Everman, J. L.Sajuthi, S. P.Zweigart, M. R.Dong, S.McBride, J.Cooley, M. R.Hines, J. B.Love, M. K.Groshong, S. D.VanSchoiack, A.Phelan, S. J.Liang, Y.Hether, T.Leon, M.Zumwalt, R. E.Barton, L. M.Duval, E. J.Mukhopadhyay, S.Stroberg, E.Borczuk, A.Thorne, L. B.Sakthivel, M. K.Lee, Y. Z.Hagood, J. S.Mock, J. R.Seibold, M. A.O'Neal, W. K.Montg2022-02-15doi:10.1101/2022.02.15.480515Cold Spring Harbor Laboratory Press2022-02-15
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A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2
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https://biorxiv.org/cgi/content/short/2021.06.28.450181v1?rss=1"
Jiang, L.Driedonks, T.Lowman, M.Jong, W. S.van den Berg van Saparoea, H. B.Dhakal, S.Zhou, R.Caputo, C.Littlefield, K.Sitaris, I.Chen, M. W.Lima, G.Gololobova, O.Smith, B.Lane, A. P.Klein, S. L.Pekosz, A.Brayton, C. F.Luirink, J.Villano, J. S.Witwer, K. W.2021-06-28doi:10.1101/2021.06.28.450181Cold Spring Harbor Laboratory Press2021-06-28
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Neutralization and Stability of SARS-CoV-2 Omicron Variant
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https://biorxiv.org/cgi/content/short/2021.12.16.472934v1?rss=1"
Cong, Z.Evans, J. P.Qu, P.Faraone, J.Zheng, Y.-M.Carlin, C.Bednash, J. S.Zhou, T.Lozanski, G.Mallampalli, R.Saif, L. J.Oltz, E. M.Mohler, P.Xu, K.Gumina, R. J.Liu, S.-L.2021-12-20doi:10.1101/2021.12.16.472934Cold Spring Harbor Laboratory Press2021-12-20
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Durability of the Neutralizing Antibody Response to mRNA Booster Vaccination Against SARS-CoV-2 BA.2.12.1 and BA.4/5 Variants
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https://biorxiv.org/cgi/content/short/2022.07.21.501010v1?rss=1"
QU, P.Faraone, J. N.Evans, J. P.Zheng, Y.-M.Carlin, C.Lozanski, G.Saif, L. J.Oltz, E. M.Gumina, R. J.Liu, S.-L.2022-07-22doi:10.1101/2022.07.21.501010Cold Spring Harbor Laboratory Press2022-07-22