bioRxiv Channel: NeurotechEU
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Audiovisual adaptation is expressed in spatial and decisional codes
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https://biorxiv.org/cgi/content/short/2021.02.15.431309v1?rss=1"
Aller, M.Mihalik, A.Noppeney, U.2021-02-17doi:10.1101/2021.02.15.431309Cold Spring Harbor Laboratory Press2021-02-17
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Differential functional neural circuitry behind autism subtypes with marked imbalance between social-communicative and restricted repetitive behavior symptom domains
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https://biorxiv.org/cgi/content/short/2020.05.08.083758v1?rss=1"
RRB, and RRB>SC subtype predictions. Applying this model to resting state fMRI data from the EU-AIMS LEAP dataset (n=509), we find that while the phenotypic subtypes share many commonalities in terms of intrinsic functional connectivity, they also show replicable differences within some networks compared to a typically-developing group (TD). Specifically, the somatomotor network is hypoconnected with perisylvian circuitry in SC>RRB and visual association circuitry in SC=RRB. The SC=RRB subtype show hyperconnectivity between medial motor and anterior salience circuitry. Genes that are highly expressed within these networks show a differential enrichment pattern with known autism-associated genes, indicating that such circuits are affected by differing autism-associated genomic mechanisms. These results suggest that SC-RRB imbalance subtypes share many commonalities, but also express subtle differences in functional neural circuitry and the genomic underpinnings behind such circuitry.
]]>Bertelsen, N.Landi, I.Bethlehem, R. A. I.Seidlitz, J.Busuoli, E. M.Mandelli, V.Satta, E.Trakoshis, S.Auyeung, B.Kundu, P.Loth, E.Dumas, G.Baumeister, S.Beckmann, C. F.Bolte, S.Bourgeron, T.Charman, T.Durston, S.Ecker, C.Holt, R.Johnson, M. H.Jones, E. J. H.Mason, L.Meyer-Lindenberg, A.Moessnang, C.Oldehinkel, M.Persico, A.Tillmann, J.Williams, S. C. R.Spooren, W.Murphy, D. G. M.Buitelaar, J. K.EU-AIMS LEAP group,Baron-Cohen, S.Lai, M.-C.Lombardo, M. V.2020-05-10doi:10.1101/2020.05.08.083758Cold Spring Harbor Laboratory Press2020-05-10
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Reducing the efforts to create reproducible analysis code with FieldTrip
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https://biorxiv.org/cgi/content/short/2021.02.05.429886v1?rss=1"
van Es, M. W. J.Spaak, E.Schoffelen, J.-M.Oostenveld, R.2021-02-08doi:10.1101/2021.02.05.429886Cold Spring Harbor Laboratory Press2021-02-08
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Rapid processing and quantitative evaluation of multicontrast EPImix scans for adaptive multimodal imaging
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https://biorxiv.org/cgi/content/short/2021.02.12.430956v1?rss=1"
View larger version (33K):
org.highwire.dtl.DTLVardef@3ae0e9org.highwire.dtl.DTLVardef@1840d39org.highwire.dtl.DTLVardef@80339borg.highwire.dtl.DTLVardef@bc16cf_HPS_FORMAT_FIGEXP M_FIG Graphical abstract.
C_FIG
]]>Vasa, F.Hobday, H.Stanyard, R. A.Daws, R. E.Giampietro, V.ODaly, O.Lythgoe, D. J.Seidlitz, J.Skare, S.Williams, S. C. R.Marquand, A. F.Leech, R.Cole, J. H.2021-02-16doi:10.1101/2021.02.12.430956Cold Spring Harbor Laboratory Press2021-02-16
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Genetic Association Study of Childhood Aggression across raters, instruments and age
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https://biorxiv.org/cgi/content/short/854927v1?rss=1"
Ip, H. F.van der Laan, C. M.Brikell, I.Sanchez-Mora, C.Nolte, I. M.St Pourcain, B.Bolhuis, K.Palviainen, T.Zafarmand, H.Colodro-Conde, L.Gordon, S.Zayats, T.Aliev, F.Jiang, C.Wang, C. A.Saunders, G.Karhunen, V.Hammerschlag, A. R.Adkins, D. E.Border, R.Peterson, R. E.Prinz, J. A.Thiering, E.Seppälä, I.Vilor-Tejedor, N.Ahluwalia, T. S.Day, F. R.Hottenga, J.-J.Allegrini, A. G.Krapohl, E. M. L.Rimfeld, K.Chen, Q.Lu, Y.Martin, J.Soler Artigas, M.Rovira, P.Bosch, R.Espanol, G.Ramos Quiroga, J. A.Neumann, A.Ensink, J.2019-11-29doi:10.1101/854927Cold Spring Harbor Laboratory Press2019-11-29
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Induction of peri-implantation stage synthetic embryos using reprogramming paradigms in ESCs
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https://biorxiv.org/cgi/content/short/2021.01.25.428068v1?rss=1"
Langkabel, J.Horne, A.Bonaguro, L.Hesse, T.Knaus, A.Riedel, Y.Händler, K.Bassler, K.Reusch, N.Yeghiazarian, L. H.Pecht, T.Aschenbrenner, A. C.Kaiser, F.Kubaczka, C.Schultze, J. L.Schorle, H.2021-01-25doi:10.1101/2021.01.25.428068Cold Spring Harbor Laboratory Press2021-01-25
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Non-linearity matters: a deep learning solution to the generalization of hidden brain patterns across population cohorts
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https://biorxiv.org/cgi/content/short/2021.03.10.434856v1?rss=1"
Zabihi, M.Kia, S. M.Wolfers, T.Dinga, R.Llera, A.Bzdok, D.Beckmann, C.marquand, A.2021-03-14doi:10.1101/2021.03.10.434856Cold Spring Harbor Laboratory Press2021-03-14
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Shared genetic influences on resting-state functional networks of the brain
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https://biorxiv.org/cgi/content/short/2021.02.15.431231v1?rss=1"
Guimaraes, J. P. O. F. T.Sprooten, E.Beckmann, C. F.Franke, B.Bralten, J.2021-02-15doi:10.1101/2021.02.15.431231Cold Spring Harbor Laboratory Press2021-02-15
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Personalized Closed-Loop Brain Stimulation for Effective Neurointervention Across Participants
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https://biorxiv.org/cgi/content/short/2021.03.18.436018v1?rss=1"
van Bueren, N.Reed, T.Nguyen, V.Sheffield, J.van der Ven, S.Osborne, M.Kroesbergen, E.Cohen Kadosh, R.2021-03-18doi:10.1101/2021.03.18.436018Cold Spring Harbor Laboratory Press2021-03-18
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Defensive freezing and its relation to approach-avoidance decision-making under threat
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https://biorxiv.org/cgi/content/short/2021.01.29.428809v1?rss=1"
Klaassen, F. H.Held, L.Figner, B.O'Reilly, J. X.Klumpers, F.de Voogd, L. D.Roelofs, K.2021-02-01doi:10.1101/2021.01.29.428809Cold Spring Harbor Laboratory Press2021-02-01
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Brain age relates to early life factors but not to accelerated brain aging
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https://biorxiv.org/cgi/content/short/2021.02.08.428915v1?rss=1"
Vidal-Pineiro, D.Wang, Y.Krogsrud, S. K.Amlien, I. K.Baare, W. F.Bartres-Faz, D.Bertram, L.Brandmaier, A. M.Drevon, C. A.Duzel, S.Ebmeier, K. P.Henson, R. N.Junque, C.Kievit, R.Kuhn, S.Leonardsen, E.Lindenberger, U.Madsen, K. S.Magnussen, F.Mowinckel, A. M.Nyberg, L.Roe, J. M.Segura, B.Sorensen, O.Suri, S.Zsoldos, E.AIBL,Walhovd, K. B.Fjell, A. M.2021-02-08doi:10.1101/2021.02.08.428915Cold Spring Harbor Laboratory Press2021-02-08
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Social prediction modulates activity of macaque superior temporal cortex
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https://biorxiv.org/cgi/content/short/2021.01.22.427803v1?rss=1"
Roumazeilles, L.Schurz, M.Lojkiewiez, M.Verhagen, L.Schuffelgen, U.Marche, K.Mahmoodi, A.Emberton, A.Simpson, K.Joly, O.Khamassi, M.Rushworth, M. F.Mars, R. B.Sallet, J.2021-01-23doi:10.1101/2021.01.22.427803Cold Spring Harbor Laboratory Press2021-01-23
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Individual variation in brain microstructural-cognition relationships in aging
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https://biorxiv.org/cgi/content/short/2021.02.19.431732v1?rss=1"
Patel, R.Mackay, C. E.Jansen, M. G.Devenyi, G.O'Donoghue, M. C.Kivimäki, M.Singh-Manoux, A.Zsoldos, E.Ebmeier, K. P.Chakravarty, M.Suri, S.2021-02-20doi:10.1101/2021.02.19.431732Cold Spring Harbor Laboratory Press2021-02-20
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Cross-sectional analysis of the microbiota of the human gut and their direct environment (exposome) in a household cohort in northern Vietnam.
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https://biorxiv.org/cgi/content/short/2021.02.23.432416v1?rss=1"
Vu Thi Ngoc, B.Ho Bich, H.Galazzo, G.Vu Tien Viet, D.Oomen, M.Nghiem Nguyen Minh, T.Tran Huy, H.Van Doorn, R.Wertheim, H. F.Penders, J.2021-02-23doi:10.1101/2021.02.23.432416Cold Spring Harbor Laboratory Press2021-02-23
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The within-host evolutionary dynamics of seasonal and pandemic human influenza A viruses in young children
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https://biorxiv.org/cgi/content/short/2021.03.20.436248v1?rss=1"
Han, A. X.Felix Garza, Z. C.Welkers, M. R. A.Vigeveno, R. M.Tran, N. D.Le, T. Q. M.Pham, Q. T.Tran, T. N. A.Ha, M. T.Nguyen, T. H.Le, Q. T.Le, T. H.Hoang, T. B. N.Chokephaibulkit, K.Puthavathana, P.Nguyen, V. V. C.Nghiem, M. N.Tran, T. H.Wertheim, H. F. L.Horby, P.Fox, A.van Doorn, H. R.Eggink, D.de Jong, M. D.Russell, C. A.2021-03-20doi:10.1101/2021.03.20.436248Cold Spring Harbor Laboratory Press2021-03-20
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Kawasaki Disease patient stratification and pathway analysis based on host transcriptomic and proteomic profiles
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https://biorxiv.org/cgi/content/short/2021.03.18.435948v1?rss=1"
Jackson, H.Menikou, S.Hamilton, S.McArdle, A.Shimizu, C.Galassini, R.Huang, H.Kim, J.Tremoulet, A.de Jonge, M.Kuijpers, T. W.Wright, V.Burns, J.Casals-Pascual, C.Herberg, J.Levin, M.Kaforou, M.The PERFORM Consortium,2021-03-19doi:10.1101/2021.03.18.435948Cold Spring Harbor Laboratory Press2021-03-19
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Individualized characterization of volumetric development in the preterm brain
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https://biorxiv.org/cgi/content/short/2020.08.05.228700v1?rss=1"
Dimitrova, R.Arulkumaran, S.Carney, O.Chew, A.Falconer, S.Ciarrusta, J.Wolfers, T.Batalle, D.Cordero-Grande, L.Price, A. N.Teixeira, R. P.Hughes, E.Egloff, A.Hutter, J.Makropoulos, A.Robinson, E. C.Schuh, A.Vecchiato, K.Steinweg, J. K.Macleod, R.Marquand, A. F.McAlonan, G.Rutherford, M. A.Counsell, S. J.Smith, S. M.Rueckert, D.Hajnal, J. V.O'Muircheartaigh, J.Edwards, A. D.2020-08-05doi:10.1101/2020.08.05.228700Cold Spring Harbor Laboratory Press2020-08-05
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Cell cycle corruption in a preleukemic ETV6-RUNX1 model exposes RUNX1 addiction as a therapeutic target in acute lymphoblastic leukemia
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https://biorxiv.org/cgi/content/short/2020.12.22.423823v1?rss=1"
Wray, J. P.Deltcheva, E. M.Boiers, C.Richardson, S. E.Chettri, J. B.Gagrica, S.Guo, Y.Illendula, A.Martens, J. H.Stunnenberg, H. H.Bushweller, J. H.Nimmo, R.Enver, T.2020-12-22doi:10.1101/2020.12.22.423823Cold Spring Harbor Laboratory Press2020-12-22
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Cortico-amygdalar connectivity and externalizing/internalizing behavior in children with neurodevelopmental disorders
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https://biorxiv.org/cgi/content/short/2021.02.01.429143v1?rss=1"
Nakua, H.Hawco, C.Forde, N. J.Jacobs, G. R.Joseph, M.Voineskos, A.Wheeler, A. L.Lai, M.-C.Szatmari, P.Kelley, E.Liu, X.Georgiades, S.Nicolson, R.Schachar, R.Crosbie, J.Anagnostou, E.Lerch, J. P.Arnold, P. D.Ameis, S. H.2021-02-02doi:10.1101/2021.02.01.429143Cold Spring Harbor Laboratory Press2021-02-02
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pyControl: Open source, Python based, hardware and software for controlling behavioural neuroscience experiments.
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https://biorxiv.org/cgi/content/short/2021.02.22.432227v1?rss=1"
Akam, T.Lustig, A.Rowland, J.Kapanaiah, S. K. T.Esteve-Agraz, J.Panniello, M.Marquez, C.Kohl, M.Kätzel, D.Costa, R. M.Walton, M. E.2021-02-23doi:10.1101/2021.02.22.432227Cold Spring Harbor Laboratory Press2021-02-23
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Sex-Dependent Shared and Non-Shared Genetic Architecture Across Mood and Psychotic Disorders
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https://biorxiv.org/cgi/content/short/2020.08.13.249813v1?rss=1"
Blokland, G. A.Grove, J.Chen, C.-Y.Cotsapas, C.Tobet, S.Handa, R.Schizophrenia Working Group of the Psychiatric Genomics Consortium,St Clair, D.Lencz, T.Mowry, B. J.Periyasamy, S.Cairns, M. J.Tooney, P. A.Wu, J. Q.Kelly, B.Kirov, G.Sullivan, P. F.Corvin, A.Riley, B. P.Esko, T.Milani, L.Jönsson, E. G.Palotie, A.Ehrenreich, H.Begemann, M.Steixner-Kumar, A.Sham, P. C.Iwata, N.Weinberger, D. R.Gejman, P. V.Sanders, A. R.Buxbaum, J. D.Rujescu, D.Giegling, I.Konte, B.Hartmann, A. M.Bramon, E.Murray, R. M.Pato, M. T.Lee,2020-08-17doi:10.1101/2020.08.13.249813Cold Spring Harbor Laboratory Press2020-08-17
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Germline loss-of-function variants in the base-excision repair gene MBD4 cause a Mendelian recessive syndrome of adenomatous colorectal polyposis and acute myeloid leukaemia
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https://biorxiv.org/cgi/content/short/2021.04.27.441137v1?rss=1"
TpG mutations, resembling mutational signature SBS1. MBD4-deficient adenomas harbour mutations in known CRC driver genes, although AMER1 mutations were more common and KRAS mutations less frequent. We did not find an increased risk for colorectal tumours in individuals with a monoallelic MBD4 LOF variant. We suggest that this condition should be termed MBD4-associated neoplasia syndrome (MANS) and that MBD4 is included in testing for the genetic diagnosis of polyposis and/or early-onset AML.
]]>Palles, C.Chew, E.Grolleman, J. E.Galavotti, S.Flensburg, C.Jansen, E. A. M.Curley, H.Chegwidden, L.Arbe Barnes, E.Bajel, A.Sherwood, K.Martin, L.Thomas, H.Georgiou, D.Fostira, F.Goldberg, Y.Adams, D.van der Biezen, S.Christie, M.Clendenning, M.Deltas, C.Dimovski, A. J.Dymerska, D.Lubinski, J.Mahmood, K.van der Post, R. S.Sanders, M.Weitz, J.Taylor, J. C.Turnbull, C.Vreede, L.van Wezel, T.Whalley, C.Arnedo Pac, C.Caravagna, G.Cross, W.Chubb, D.Frangou, A.Gruber, A.Kinnersley, B.Noyvert, B.Church, D.Graham, T.2021-04-28doi:10.1101/2021.04.27.441137Cold Spring Harbor Laboratory Press2021-04-28
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Warped Bayesian Linear Regression for Normative Modelling of Big Data
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https://biorxiv.org/cgi/content/short/2021.04.05.438429v1?rss=1"
Fraza, C.Dinga, R.Beckmann, C. F.Marquand, A. F.2021-04-06doi:10.1101/2021.04.05.438429Cold Spring Harbor Laboratory Press2021-04-06
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Post mortem mapping of connectional anatomy for the validation of diffusion MRI
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https://biorxiv.org/cgi/content/short/2021.04.16.440223v1?rss=1"
Yendiki, A.Aggarwal, M.Axer, M.Howard, A. F.van Cappellen van Walsum, A.-M.Haber, S. N.2021-04-19doi:10.1101/2021.04.16.440223Cold Spring Harbor Laboratory Press2021-04-19
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Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium
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https://biorxiv.org/cgi/content/short/2021.05.05.442735v1?rss=1"
Sha, Z.Rooij, D. v.Anagnostou, E.Arango, C.Auzias, G.Behrmann, M.Bernhardt, B.Bolte, S.Busatto, G. F.Calderoni, S.Calvo, R.Daly, E.Deruelle, C.Duan, M.Duran, F. L. S.Durston, S.Ecker, C.Ehrlich, S.Fair, D.Fedor, J.Fitzgerald, J.Floris, D. L.Franke, B.Freitag, C. M.Gallagher, L.Glahn, D. C.Haar, S.Hoekstra, L.Jahanshad, N.Jalbrzikowski, M.Janssen, J.King, J. A.Lazaro, L.Luna, B.McGrath, J.Medland, S. E.Molloy, C.Muratori, F.Murphy, D. G. M.Neufeld, J.O'Hearn, K.Oranje, B.Parellada, M.Pariente, J.Postema, M.2021-05-06doi:10.1101/2021.05.05.442735Cold Spring Harbor Laboratory Press2021-05-06
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Clone expansion of mutation-driven clonal hematopoiesis is associated with aging and metabolic dysfunction in individuals with obesity
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https://biorxiv.org/cgi/content/short/2021.05.12.443095v1?rss=1"
van Deuren, R. C.Andersson-Assarsson, J. C.Kristensson, F. M.Steehouwer, M.Sjöholm, K.Svensson, P.-A.Peterse, M.Gilissen, C.Taube, M.Jacobson, P.Perkins, R.Brunner, H. G.Netea, M. G.Peltonen, M.Carlsson, B.Hoischen, A.Carlsson, L. M.2021-05-13doi:10.1101/2021.05.12.443095Cold Spring Harbor Laboratory Press2021-05-13
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The Immunological Factors Predisposing To Severe COVID-19 Are Already Present In Healthy Elderly And Men
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https://biorxiv.org/cgi/content/short/2021.04.30.442229v1?rss=1"
Kilic, G.Bulut, O.Jaeger, M.ter Horst, R.Koeken, V.Moorlag, S. J. C. F. M.Mourits, V.de Bree, C.Dominguez-Andres, J.Joosten, L. A. B.Netea, M.2021-05-04doi:10.1101/2021.04.30.442229Cold Spring Harbor Laboratory Press2021-05-04
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Topographic divergence of atypical cortical asymmetry and regional atrophy patterns in temporal lobe epilepsy: a worldwide enigma study
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https://biorxiv.org/cgi/content/short/2021.04.30.442117v1?rss=1"
Park, B.-y.Lariviere, S.Rodriguez-Cruces, R.Royer, J.Tavakol, S.Wang, Y.Caciagli, L.Caligiuri, M. E.Gambardella, A.Concha, L.Keller, S. S.Cendes, F.Alvim, M. K.Yasuda, C.Bonilha, L.Gleichgerrcht, E.Focke, N. K.Kreilkamp, B. A.Domin, M.von Podewils, F.Langner, S.Rummel, C.Rebsamen, M.Wiest, R.Martin, P.Kotikalapudi, R.Bender, B.O'Brien, T. J.Law, M.Sinclair, B.Vivash, L.Desmond, P. M.Malpas, C. B.Lui, E.Alhusaini, S.Doherty, C. P.Cavalleri, G. L.Delanty, N.Kalviainen, R.Jackson, G. D.Kowalczyk, M.Mascalchi, M.Se2021-04-30doi:10.1101/2021.04.30.442117Cold Spring Harbor Laboratory Press2021-04-30
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Associations between ADHD symptom remission and white matter microstructure: a longitudinal analysis
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https://biorxiv.org/cgi/content/short/2020.09.24.311654v1?rss=1"
Damatac, C. G.Leenders, A. E. M.Soheili-Nezhad, S.Chauvin, R. J. M.Mennes, M. J. J.Zwiers, M. P.van Rooij, D.Akkermans, S. E. A.Naaijen, J.Franke, B.Buitelaar, J. K.Beckmann, C. F.Sprooten, E.2020-09-25doi:10.1101/2020.09.24.311654Cold Spring Harbor Laboratory Press2020-09-25
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Scaling principles of white matter brain connectivity
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https://biorxiv.org/cgi/content/short/2021.05.31.445808v1?rss=1"
Ardesch, D. J.Scholtens, L. H.de Lange, S. C.Roumazeilles, L.Khrapitchev, A. A.Preuss, T. M.Rilling, J. K.Mars, R. B.van den Heuvel, M. P.2021-05-31doi:10.1101/2021.05.31.445808Cold Spring Harbor Laboratory Press2021-05-31
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Federated Multi-Site Normative Modeling using Hierarchical Bayesian Regression
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https://biorxiv.org/cgi/content/short/2021.05.28.446120v1?rss=1"
Kia, S. M.Huijsdens, H.Rutherford, S.Dinga, R.Wolfers, T.Mennes, M.Andreassen, O.Westlye, L. T.Beckmann, C. F.Marquand, A. F.2021-05-30doi:10.1101/2021.05.28.446120Cold Spring Harbor Laboratory Press2021-05-30
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Rare copy number variants (CNVs) and breast cancer risk
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https://biorxiv.org/cgi/content/short/2021.05.20.444828v1?rss=1"
Dennis, J.Tyrer, J. P.Walker, L. C.Michailidou, K.Dorling, L.Bolla, M. K.Wang, Q.Ahearn, T. U.Andrulis, I. L.Anton-Culver, H.Antonenkova, N. N.Arndt, V.Aronson, K. J.Beane Freeman, L. E.Beckmann, M. W.Behrens, S.Benitez, J.Bermisheva, M.Bogdanova, N. V.Bojesen, S. E.Brenner, H.Castelao, J. E.Chang-Claude, J.Chenevix-Trench, G.Clarke, C. L.Collaborators, N.Collee, J. M.Consortium, C.Couch, F. J.Cox, A.Cross, S. S.Czene, K.Devilee, P.Dork, T.Dossus, L.Eliassen, A. H.Eriksson, M.Evans, D. G.Fasching, P. A.Figueroa, J.2021-05-21doi:10.1101/2021.05.20.444828Cold Spring Harbor Laboratory Press2021-05-21
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Synthetic Antigen Presenting cells reveal the diversity and functional specialization of extracellular vesicles composing the fourth signal of T cell immunological synapses.
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https://biorxiv.org/cgi/content/short/2021.05.29.445691v1?rss=1"
View larger version (67K):
org.highwire.dtl.DTLVardef@100f3aorg.highwire.dtl.DTLVardef@57adfforg.highwire.dtl.DTLVardef@6052fcorg.highwire.dtl.DTLVardef@1e85c21_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIBead Supported Lipid Bilayers (BSLB) reconstituting antigen-presenting cells support synapse assembly by T cells and the release of effector particles.
C_LIO_LIBSLB facilitate the dissection of the cellular machineries and synapse composition shaping the released tSV.
C_LIO_LItSV and their steadily released counterparts have a different composition. TSV show a higher enrichment of effectors including immune receptors, miR, RNA- and other nucleic acid-binding proteins, than EVs.
C_LI
]]>Cespedes, P. F.Jainarayanan, A. K.Fernandez-Messina, L.Valvo, S.Saliba, D. G.Kvalvaag, A.Kurz, E.Colin-York, H.Fritzsche, M.Yanchun, P.Dong, T.Siller-Farfan, J. A.Dushek, O.Maj, M.Sezgin, E.Peacock, B.Law, A.Aubert, D.Engledow, S.Attar, M.Sanchez-Madrid, F.Hester, S.Fisher, R.Dustin, M. L.2021-05-29doi:10.1101/2021.05.29.445691Cold Spring Harbor Laboratory Press2021-05-29
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Diffusion and interaction dynamics of the cytosolic peroxisomal import receptor PEX5
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https://biorxiv.org/cgi/content/short/2021.05.25.445571v1?rss=1"
Galiani, S.Reglinski, K.Carravilla, P.Barbotin, A.Urbancic, I.Ott, J.Sehr, J.Sezgin, E.Schneider, F.Waithe, D.Hublitz, P.Schliebs, W.Erdmann, R.Eggeling, C.2021-05-26doi:10.1101/2021.05.25.445571Cold Spring Harbor Laboratory Press2021-05-26
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PET-BIDS, an extension to the brain imaging data structure for positron emission tomography
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https://biorxiv.org/cgi/content/short/2021.06.16.448390v1?rss=1"
Norgaard, M.Matheson, G. J.Hansen, H. D.Thomas, A. G.Searle, G.Rizzo, G.Veronese, M.Giacomel, A.Yaqub, M.Tonietto, M.Funck, T.Gillman, A.Boniface, H.Routier, A.Dalenberg, J. R.Betthauser, T.Feingold, F.Markiewicz, C. J.Gorgolewski, K. J.Blair, R. W.Appelhoff, S.Gau, R.Salo, T.Niso, G.Pernet, C.Phillips, C.Oostenveld, R.Carson, R. E.Gallezot, J.-D.Knudsen, G. M.Innis, R. B.Ganz, M.2021-06-17doi:10.1101/2021.06.16.448390Cold Spring Harbor Laboratory Press2021-06-17
<![CDATA[
The Digital Brain Bank: an open access platform for post-mortem datasets
]]>
https://biorxiv.org/cgi/content/short/2021.06.21.449154v1?rss=1"
Tendler, B. C.Hanayik, T.Ansorge, O.Bangerter-Christensen, S.Berns, G. S.Bertelsen, M. F.Bryant, K. L.Foxley, S.Howard, A. F. D.Huszar, I.Khrapitchev, A. A.Leonte, A.Manger, P. R.Menke, R. A. L.Mollink, J.Mortimer, D.Pallebage-Gamarallage, M.Roumazeilles, L.Sallet, J.Scott, C.Smart, A.Turner, M. R.Wang, C.Jbabdi, S.Mars, R. B.Miller, K. L.2021-06-22doi:10.1101/2021.06.21.449154Cold Spring Harbor Laboratory Press2021-06-22
<![CDATA[
Heterogeneous relationships between white matter and behaviour
]]>
https://biorxiv.org/cgi/content/short/2020.12.15.422826v1?rss=1"
Lazari, A.Salvan, P.Cottaar, M.Papp, D.van der Werf, O. J.Johnstone, A.Sanders, Z.-B.Sampaio-Baptista, C.Eichert, N.Miyamoto, K.Winkler, A.Callaghan, M. F.Nichols, T. E.Stagg, C. J.Rushworth, M.Verhagen, L.Johansen-Berg, H.2020-12-15doi:10.1101/2020.12.15.422826Cold Spring Harbor Laboratory Press2020-12-15
<![CDATA[
Metabolic resilience is encoded in genome plasticity
]]>
https://biorxiv.org/cgi/content/short/2021.06.25.449953v1?rss=1"
Agudelo, L. Z.Tuyeras, R. V.Llinares, C.Morcuende, A.Park, Y.Sun, N.Kuosmanen, S. M.Atabaki-Pasdar, N.Ho, L.-L.Galani, K.Franks, P. W.Kutlu, B.Grove, K.Femenia, T.Kellis, M.2021-06-27doi:10.1101/2021.06.25.449953Cold Spring Harbor Laboratory Press2021-06-27
<![CDATA[
STED super-resolution imaging of membrane packing and dynamics by exchangeable polarity-sensitive dyes
]]>
https://biorxiv.org/cgi/content/short/2021.06.05.446432v1?rss=1"
Carravilla, P.Dasgupta, A.Zhurgenbayeva, G.Danylchuk, D. I.Klymchenko, A. S.Sezgin, E.Eggeling, C.2021-06-05doi:10.1101/2021.06.05.446432Cold Spring Harbor Laboratory Press2021-06-05
<![CDATA[
Spatiotemporally flexible subnetworks reveal the quasi-cyclic nature of integration and segregation in the human brain.
]]>
https://biorxiv.org/cgi/content/short/2021.06.09.447672v1?rss=1"
Strindberg, M.Fransson, P.Cabral, J.Aden, U.2021-06-09doi:10.1101/2021.06.09.447672Cold Spring Harbor Laboratory Press2021-06-09
<![CDATA[
Brain charts for the human lifespan
]]>
https://biorxiv.org/cgi/content/short/2021.06.08.447489v1?rss=1"
Bethlehem, R. A. I.Seidlitz, J.White, S. R.Vogel, J. W.Anderson, K. M.Adamson, C.Adler, S.Alexopoulos, G. S.Anagnostou, E.Areces-Gonzalez, A.Astle, D. E.Auyeung, B.Ayub, M.Ball, G.Baron-Cohen, S.Beare, R.Bedford, S. A.Benegal, V.Beyer, F.Bin Bae, J.Blangero, J.Blesa Cabez, M.Boardman, J. P.Borzage, M.Bosch-Bayard, J. F.Bourke, N.Calhoun, V. D.Chakravarty, M. M.Chen, C.Chertavian, C.Chetelat, G.Chong, Y. S.Cole, J. H.Corvin, A.Courchesne, E.Crivello, F.Cropley, V. L.Crosbie, J.Crossley, N.Delarue, M.Desrivieres, S.2021-06-10doi:10.1101/2021.06.08.447489Cold Spring Harbor Laboratory Press2021-06-10
<![CDATA[
Charting Brain Growth and Aging at High Spatial Precision
]]>
https://biorxiv.org/cgi/content/short/2021.08.08.455487v1?rss=1"
Rutherford, S.Fraza, C.Dinga, R.Kia, S. M.Wolfers, T.Zabihi, M.Berthet, P.Worker, A.Verdi, S.Andrews, D.Han, L.Bayer, J.Dazzan, P.McGuire, P.Mocking, R. T.Schene, A.Sripada, C.Tso, I. F.Duval, E. R.Chang, S.-E.Pennix, B. W.Heitzeg, M. M.Burt, S. A.Hyde, L.Amaral, D.Nordahl, C. W.Andreasssen, O. A.Westlye, L. T.Zahn, R.Ruhe, H. G.Beckmann, C.Marquand, A. F.2021-08-08doi:10.1101/2021.08.08.455487Cold Spring Harbor Laboratory Press2021-08-08
<![CDATA[
The Normative Modeling Framework for Computational Psychiatry
]]>
https://biorxiv.org/cgi/content/short/2021.08.08.455583v1?rss=1"
Rutherford, S.Kia, S. M.Wolfers, T.Fraza, C.Zabihi, M.Dinga, R.Berthet, P.Worker, A.Verdi, S.Ruhe, H. G.Beckmann, C. F.Marquand, A. F.2021-08-10doi:10.1101/2021.08.08.455583Cold Spring Harbor Laboratory Press2021-08-10
<![CDATA[
Can fMRI functional connectivity index dynamic neural communication?
]]>
https://biorxiv.org/cgi/content/short/2021.07.27.453965v1?rss=1"
Alonso Martinez, S.Llera Arenas, A.Ter Horst, G. T.Vidaurre, D.2021-07-27doi:10.1101/2021.07.27.453965Cold Spring Harbor Laboratory Press2021-07-27
<![CDATA[
Arg1+ microglia are critical for shaping cognition in female mice
]]>
https://biorxiv.org/cgi/content/short/2021.08.15.456225v1?rss=1"
Stratoulias, V.Ruiz, R.Kanatani, S.Osman, A. M.Armengol, J. A.Rodriguez-Moreno, A.Murgoci, A.-N.Garcia-Dominguez, I.Keane, L.Vazquez-Carbera, G.Alonso-Bellido, I.Vernoux, N.Tejera, D.Grabert, K.Cheray, M.Gonzalez-Rodriguez, P.Perez-Villegas, E. M.Martinez-Gallego, I.Brodin, D.Avila-Carino, J.Airavaara, M.Uhlen, P.Heneka, M. T.Tremblay, M.-E.Blomgren, K.Venero, J. L.Joseph, B.2021-08-16doi:10.1101/2021.08.15.456225Cold Spring Harbor Laboratory Press2021-08-16
<![CDATA[
The spatial landscape of clonal somatic mutations in benign and malignant tissue
]]>
https://biorxiv.org/cgi/content/short/2021.07.12.452018v1?rss=1"
120 000 regions across multiple organs, in benign and malignant tissues. We demonstrate that genome-wide copy number variation reveals distinct clonal patterns within tumours and in nearby benign tissue. Our results suggest a model for how genomic instability arises in histologically benign tissue that may represent early events in cancer evolution. We highlight the power of an unsupervised approach to capture the molecular and spatial continuums in a tissue context and challenge the rationale for treatment paradigms, including focal therapy.
]]>Erickson, A.Berglund, E.He, M.Marklund, M.Mirzazadeh, R.Schultz, N.Bergenstrahle, L.Kvastad, L.Andersson, A.Bergenstrahle, J.Larsson, L.Shamikh, A.Basmaci, E.de Stahl, T. D.Rajakumar, T.Thrane, K.Ji, A. L.Khavari, P. A.Tarish, F.Tanoglidi, A.Maaskola, J.Colling, R.Mirtti, T.Hamdy, F. C.Woodcock, D. J.Helleday, T.Mills, I. G.Lamb, A. D.Lundeberg, J.2021-07-12doi:10.1101/2021.07.12.452018Cold Spring Harbor Laboratory Press2021-07-12
<![CDATA[
Global network structure and local transcriptomic vulnerability shape atrophy in sporadic and genetic behavioral variant frontotemporal dementia
]]>
https://biorxiv.org/cgi/content/short/2021.08.24.457538v1?rss=1"
Shafiei, G.Bazinet, V.Dadar, M.Manera, A. L.Collins, D. L.Dagher, A.Borroni, B.Sanchez-Valle, R.Moreno, F.Laforce, R.Graff, C.Synofzik, M.Galimberti, D.Rowe, J. B.Masellis, M.Tartaglia, M. C.Finger, E.Vandenberghe, R.de Mendonca, A.Tagliavini, F.Santana, I.Butler, C.Gerhard, A.Danek, A.Levin, J.Otto, M.Sorbi, S.Jiskoot, L. C.Seelaar, H.van Swieten, J. C.Rohrer, J. D.Misic, B.Ducharme, S.Frontotemporal Lobar Degeneration Neuroimaging Initiative (FTLDNI),GENetic Frontotemporal dementia Initiative (GENFI),2021-08-26doi:10.1101/2021.08.24.457538Cold Spring Harbor Laboratory Press2021-08-26
<![CDATA[
Segregation of neural crest specific lineage trajectories from a heterogeneous neural plate border territory only emerges at neurulation
]]>
https://biorxiv.org/cgi/content/short/2021.08.08.455573v1?rss=1"
Williams, R.Lukoseviciute, M.Sauka-Spengler, T.Bronner, M. E.2021-08-08doi:10.1101/2021.08.08.455573Cold Spring Harbor Laboratory Press2021-08-08
<![CDATA[
Neuromesodermal progenitor origin of trunk neural crest in vivo
]]>
https://biorxiv.org/cgi/content/short/2021.02.10.430513v1?rss=1"
Lukoseviciute, M.Mayes, S.Sauka-Spengler, T.2021-02-10doi:10.1101/2021.02.10.430513Cold Spring Harbor Laboratory Press2021-02-10
<![CDATA[
Integrative annotation of genomic features reveal functional elements and epigenetic landscapes in the developing zebrafish
]]>
https://biorxiv.org/cgi/content/short/2021.08.09.454869v1?rss=1"
Baranasic, D.Hoertenhuber, M.Balwierz, P.Zehnder, T.Mukarram, A. K.Nepal, C.Varnai, C.Hadzhiev, Y.Jimenez-Gonzalez, A.Li, N.Wragg, J. W.D'Orazio, F.Diaz, N.Hernandez-Rodriguez, B.Chen, Z.Stoiber, M.Dong, M.Stevens, I.Ross, S. E.Eagle, A.Martin, R.Obasaju, P.Rastegar, S.McGarvey, A. C.Kopp, W.Chambers, E.Wang, D.Kim, H. K.Acemel, R. D.Naranjo, S.Lapinski, M.Chong-Morrison, V.Mathavan, S.Peers, B.Sauka-Spengler, T.Vingron, M.Carninci, P.Ohler, U.Lacadie, S. A.Burgess, S.Winata, C.van Eeden, F.Vaquerizas, J. M.G2021-08-09doi:10.1101/2021.08.09.454869Cold Spring Harbor Laboratory Press2021-08-09
<![CDATA[
Fluctuations in Neural Complexity During Wakefulness Relate To Conscious Level and Cognition
]]>
https://biorxiv.org/cgi/content/short/2021.09.23.461002v1?rss=1"
Mediano, P.Ikkala, A.Kievit, R. A.Jagannathan, S. R.Varley, T. F.Stamatakis, E. A.Bekinschtein, T. A.Bor, D.2021-09-23doi:10.1101/2021.09.23.461002Cold Spring Harbor Laboratory Press2021-09-23
<![CDATA[
Global trade-offs in tree functional traits
]]>
https://biorxiv.org/cgi/content/short/2021.09.16.458157v1?rss=1"
Maynard, D. S.Bialic-Murphy, L.Zohner, C. M.Averill, C.van den Hoogen, J.Ma, H.Mo, L.Smith, G. R.Aubin, I.Berenguer, E.Boonman, C. C. F.Catford, J.Cerabolini, B. E. L.Dias, A.Gonzalez-Melo, A.Heitz, P.Lusk, C. H.Mori, A. S.Niinemets, U.Pillar, V. D.Rosell, J. A.Schurr, F. M.Sheremetev, S. N.da Silva, A. C.Sosinski, E.van Bodegom, P. M.Weiher, E.Bönisch, G.Kattge, J.Crowther, T. W.2021-09-17doi:10.1101/2021.09.16.458157Cold Spring Harbor Laboratory Press2021-09-17
<![CDATA[
Supervised Phenotype Discovery from Multimodal Brain Imaging
]]>
https://biorxiv.org/cgi/content/short/2021.09.03.458926v1?rss=1"
Gong, W.Bai, S.Zheng, Y.-Q.Beckmann, C.Smith, S. M.2021-09-06doi:10.1101/2021.09.03.458926Cold Spring Harbor Laboratory Press2021-09-06
<![CDATA[
Diffusion MRI Anisotropy in the Cerebral Cortex is Determined by Unmyelinated Tissue Features
]]>
https://biorxiv.org/cgi/content/short/2021.09.02.458694v1?rss=1"
Reveley, C.Ye, F. Q.Mars, R. B.Leopold, D. A.2021-09-02doi:10.1101/2021.09.02.458694Cold Spring Harbor Laboratory Press2021-09-02
<![CDATA[
Sharing individualised template MRI data for MEG source reconstruction: a solution for open data while keeping subject confidentiality
]]>
https://biorxiv.org/cgi/content/short/2021.11.18.469069v1?rss=1"
Vinding, M. C.Oostenveld, R.2021-11-19doi:10.1101/2021.11.18.469069Cold Spring Harbor Laboratory Press2021-11-19
<![CDATA[
Dynamics of Brain Structure and its Genetic Architecture over the Lifespan
]]>
https://biorxiv.org/cgi/content/short/2020.04.24.031138v1?rss=1"
Brouwer, R. M.Klein, M.Grasby, K. L.Schnack, H. G.Jahanshad, N.Teeuw, J.Thomopoulos, S. I.Sprooten, E.Franz, C. E.Gogtay, N.Kremen, W.Panizzon, M. S.Olde Loohuis, L. M.Whelan, C. D.Aghajani, M.Alloza, C.Alnaes, D.Artiges, E.Ayesa-Arriola, R.Barker, G. J.Blok, E.Boen, E.Breukelaar, I. A.Bright, J. K.Buimer, E. E.Bülow, R.Cannon, D. M.Ciufolini, S.Crossley, N. A.Damatac, C. G.Dazzan, P.de Mol, C. L.de Zwarte, S. M.Desrivieres, S.Diaz-Caneja, C. M.Doan, N. T.Dohm, K.Fröhner, J. H.Goltermann, J.Grigis, A.Grotegerd, D2020-04-27doi:10.1101/2020.04.24.031138Cold Spring Harbor Laboratory Press2020-04-27
<![CDATA[
Genome-wide association analyses of individual differences in quantitatively assessed reading- and language-related skills in up to 34,000 people
]]>
https://biorxiv.org/cgi/content/short/2021.11.04.466897v1?rss=1"
Eising, E.Mirza-Schreiber, N.de Zeeuw, E. L.Wang, C. A.Truong, D. T.Allegrini, A. G.Shapland, C. Y.Zhu, G.Wigg, K. G.Gerritse, M.Molz, B.Alagoz, G.Gialluisi, A.Abbondanza, F.Rimfeld, K.Van Donkelaar, M. M.Liao, Z.Jansen, P. R.Andlauer, T. F. M.Bates, T. C.Bernard, M.Blokland, K.Borglum, A. D.Bourgeron, T.Brandeis, D.Ceroni, F.Dale, P. S.de Jong, P. F.DeFries, J. C.Demontis, D.Feng, Y.Gordon, S. D.Guger, S. L.Hayiou-Thomas, M. E.Hernandez-Cabrera, J. A.Hottenga, J.- J.Hulme, C.Kerr, E. N.Koomar, T.Landerl, K.Lovett,2021-11-04doi:10.1101/2021.11.04.466897Cold Spring Harbor Laboratory Press2021-11-04
<![CDATA[
N4BP1 is dimerization-dependent linear ubiquitin reader regulating TNFR1 signalling through linear ubiquitin binding and Caspase-8-mediated processing
]]>
https://biorxiv.org/cgi/content/short/2021.11.02.466974v1?rss=1"
Kliza, K. W.Song, W.Pinzuti, I.Schaubeck, S.Kunzelmann, S.Kuntin, D.Fornili, A.Pandini, A.Hofmann, K.Garnett, J.Stieglitz, B.Husnjak, K.2021-11-02doi:10.1101/2021.11.02.466974Cold Spring Harbor Laboratory Press2021-11-02
<![CDATA[
The influence of the extracellular domains on the dynamic behavior of membrane proteins
]]>
https://biorxiv.org/cgi/content/short/2021.11.15.468619v1?rss=1"
Wedemann, L.Gurdap, C. O.Sych, T.Sezgin, E.2021-11-16doi:10.1101/2021.11.15.468619Cold Spring Harbor Laboratory Press2021-11-16
<![CDATA[
Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia
]]>
https://biorxiv.org/cgi/content/short/2021.11.12.468429v1?rss=1"
Bussy, A.Levy, J.Patel, R.Cupo, L.Best, T.Van Langenhove, T.Nielsen, J.Pijnenburg, Y.Landqvist Waldö, M.Remes, A.Schroeter, M. L.Santana, I.Pasquier, F.Otto, M.Danek, A.Levin, J.Le Ber, I.Vandenberghe, R.Synofzik, M.Moreno, F.de Mendonca, A.Sanchez-Valle, R.Laforce, R.Langheinrich, T.Gerhard, A.Graff, C.Butler, C. R.Sorbi, S.Jiskoot, L.Seelaar, H.van Swieten, J. C.Finger, E.Tartaglia, M. C.Masellis, M.Tiraboschi, P.Galimberti, D.Borroni, B.Rowe, J.Bocchetta, M.Rohrer, J. D.Devenyi, G. A.Chakravarty, M. M.Ducha2021-11-16doi:10.1101/2021.11.12.468429Cold Spring Harbor Laboratory Press2021-11-16
<![CDATA[
Uncovering the Genetic Architecture of Broad Antisocial Behavior through a Genome-Wide Association Study Meta-analysis.
]]>
https://biorxiv.org/cgi/content/short/2021.10.19.462578v1?rss=1"
Tielbeek, J. J.Uffelmann, E.Williams, B. S.Colodro-Conde, L.Gagnon, E.Mallard, T. T.Levitt, B. E.Jansen, P. R.Johansson, A.Sallis, H. M.Pistis, G.Saunders, G. R.Allegrini, A. G.Rimfeld, K.Konte, B.Klein, M.Hartmann, A. M.Salvatore, J. E.Nolte, I. M.Demontis, D.Malmberg, A.Burt, S. A.Savage, J. E.Sugden, K.Poulton, R.Harris, K. M.Vrieze, S.McGue, M.Iacono, W. G.Mota, N. R.Mill, J.Viana, J. F.Mitchell, B. L.Morosoli, J. J.Andlauer, T. F. M.Ouellet-Morin, I.Tremblay, R. E.Cote, S. M.Gouin, J.-P.Brendgen, M. R.Dionne,2021-10-20doi:10.1101/2021.10.19.462578Cold Spring Harbor Laboratory Press2021-10-20
<![CDATA[
COVID Moonshot: Open Science Discovery of SARS-CoV-2 Main Protease Inhibitors by Combining Crowdsourcing, High-Throughput Experiments, Computational Simulations, and Machine Learning
]]>
https://biorxiv.org/cgi/content/short/2020.10.29.339317v1?rss=1"
18,000 designs), crystallographic data (>840 ligand-bound X-ray structures), assay data (>10,000 measurements), and synthesized molecules (>2,400 compounds) for this campaign were shared rapidly and openly, creating a rich open and IP-free knowledgebase for future anti-coronavirus drug discovery.
]]>The COVID Moonshot Consortium,Achdout, H.Aimon, A.Bar-David, E.Barr, H.Ben-Shmuel, A.Bennett, J.Bobby, M. L.Brun, J.BVNBS, S.Calmiano, M.Carbery, A.Cattermole, E.Chodera, J. D.Clyde, A.Coffland, J. E.Cohen, G.Cole, J.Contini, A.Cox, L.Cvitkovic, M.Dias, A.Douangamath, A.Duberstein, S.Dudgeon, T.Dunnett, L.Eastman, P. K.Erez, N.Fairhead, M.Fearon, D.Fedorov, O.Ferla, M.Foster, H.Foster, R.Gabizon, R.Gehrtz, P.Gileadi, C.Giroud, C.Glass, W. G.Glen, R.Glinert, I.Gorichko, M.Gorrie-Stone, T.Griffen, E. J.Heer2020-10-30doi:10.1101/2020.10.29.339317Cold Spring Harbor Laboratory Press2020-10-30