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https://biorxiv.org/cgi/content/short/2021.02.15.431309v1?rss=1"
Aller, M.Mihalik, A.Noppeney, U.2021-02-17doi:10.1101/2021.02.15.431309Cold Spring Harbor Laboratory Press2021-02-17
https://biorxiv.org/cgi/content/short/2020.05.08.083758v1?rss=1"
RRB, and RRB>SC subtype predictions. Applying this model to resting state fMRI data from the EU-AIMS LEAP dataset (n=509), we find that while the phenotypic subtypes share many commonalities in terms of intrinsic functional connectivity, they also show replicable differences within some networks compared to a typically-developing group (TD). Specifically, the somatomotor network is hypoconnected with perisylvian circuitry in SC>RRB and visual association circuitry in SC=RRB. The SC=RRB subtype show hyperconnectivity between medial motor and anterior salience circuitry. Genes that are highly expressed within these networks show a differential enrichment pattern with known autism-associated genes, indicating that such circuits are affected by differing autism-associated genomic mechanisms. These results suggest that SC-RRB imbalance subtypes share many commonalities, but also express subtle differences in functional neural circuitry and the genomic underpinnings behind such circuitry.
]]>Bertelsen, N.Landi, I.Bethlehem, R. A. I.Seidlitz, J.Busuoli, E. M.Mandelli, V.Satta, E.Trakoshis, S.Auyeung, B.Kundu, P.Loth, E.Dumas, G.Baumeister, S.Beckmann, C. F.Bolte, S.Bourgeron, T.Charman, T.Durston, S.Ecker, C.Holt, R.Johnson, M. H.Jones, E. J. H.Mason, L.Meyer-Lindenberg, A.Moessnang, C.Oldehinkel, M.Persico, A.Tillmann, J.Williams, S. C. R.Spooren, W.Murphy, D. G. M.Buitelaar, J. K.EU-AIMS LEAP group,Baron-Cohen, S.Lai, M.-C.Lombardo, M. V.2020-05-10doi:10.1101/2020.05.08.083758Cold Spring Harbor Laboratory Press2020-05-10
https://biorxiv.org/cgi/content/short/2021.02.05.429886v1?rss=1"
van Es, M. W. J.Spaak, E.Schoffelen, J.-M.Oostenveld, R.2021-02-08doi:10.1101/2021.02.05.429886Cold Spring Harbor Laboratory Press2021-02-08
https://biorxiv.org/cgi/content/short/2021.02.12.430956v1?rss=1"
View larger version (33K):
org.highwire.dtl.DTLVardef@3ae0e9org.highwire.dtl.DTLVardef@1840d39org.highwire.dtl.DTLVardef@80339borg.highwire.dtl.DTLVardef@bc16cf_HPS_FORMAT_FIGEXP M_FIG Graphical abstract.
C_FIG
]]>Vasa, F.Hobday, H.Stanyard, R. A.Daws, R. E.Giampietro, V.ODaly, O.Lythgoe, D. J.Seidlitz, J.Skare, S.Williams, S. C. R.Marquand, A. F.Leech, R.Cole, J. H.2021-02-16doi:10.1101/2021.02.12.430956Cold Spring Harbor Laboratory Press2021-02-16
https://biorxiv.org/cgi/content/short/854927v1?rss=1"
Ip, H. F.van der Laan, C. M.Brikell, I.Sanchez-Mora, C.Nolte, I. M.St Pourcain, B.Bolhuis, K.Palviainen, T.Zafarmand, H.Colodro-Conde, L.Gordon, S.Zayats, T.Aliev, F.Jiang, C.Wang, C. A.Saunders, G.Karhunen, V.Hammerschlag, A. R.Adkins, D. E.Border, R.Peterson, R. E.Prinz, J. A.Thiering, E.Seppälä, I.Vilor-Tejedor, N.Ahluwalia, T. S.Day, F. R.Hottenga, J.-J.Allegrini, A. G.Krapohl, E. M. L.Rimfeld, K.Chen, Q.Lu, Y.Martin, J.Soler Artigas, M.Rovira, P.Bosch, R.Espanol, G.Ramos Quiroga, J. A.Neumann, A.Ensink, J.2019-11-29doi:10.1101/854927Cold Spring Harbor Laboratory Press2019-11-29
https://biorxiv.org/cgi/content/short/2021.01.25.428068v1?rss=1"
Langkabel, J.Horne, A.Bonaguro, L.Hesse, T.Knaus, A.Riedel, Y.Händler, K.Bassler, K.Reusch, N.Yeghiazarian, L. H.Pecht, T.Aschenbrenner, A. C.Kaiser, F.Kubaczka, C.Schultze, J. L.Schorle, H.2021-01-25doi:10.1101/2021.01.25.428068Cold Spring Harbor Laboratory Press2021-01-25
https://biorxiv.org/cgi/content/short/2021.03.10.434856v1?rss=1"
Zabihi, M.Kia, S. M.Wolfers, T.Dinga, R.Llera, A.Bzdok, D.Beckmann, C.marquand, A.2021-03-14doi:10.1101/2021.03.10.434856Cold Spring Harbor Laboratory Press2021-03-14
https://biorxiv.org/cgi/content/short/2021.02.15.431231v1?rss=1"
Guimaraes, J. P. O. F. T.Sprooten, E.Beckmann, C. F.Franke, B.Bralten, J.2021-02-15doi:10.1101/2021.02.15.431231Cold Spring Harbor Laboratory Press2021-02-15
https://biorxiv.org/cgi/content/short/2021.03.18.436018v1?rss=1"
van Bueren, N.Reed, T.Nguyen, V.Sheffield, J.van der Ven, S.Osborne, M.Kroesbergen, E.Cohen Kadosh, R.2021-03-18doi:10.1101/2021.03.18.436018Cold Spring Harbor Laboratory Press2021-03-18
https://biorxiv.org/cgi/content/short/2021.01.29.428809v1?rss=1"
Klaassen, F. H.Held, L.Figner, B.O'Reilly, J. X.Klumpers, F.de Voogd, L. D.Roelofs, K.2021-02-01doi:10.1101/2021.01.29.428809Cold Spring Harbor Laboratory Press2021-02-01
https://biorxiv.org/cgi/content/short/2021.02.08.428915v1?rss=1"
Vidal-Pineiro, D.Wang, Y.Krogsrud, S. K.Amlien, I. K.Baare, W. F.Bartres-Faz, D.Bertram, L.Brandmaier, A. M.Drevon, C. A.Duzel, S.Ebmeier, K. P.Henson, R. N.Junque, C.Kievit, R.Kuhn, S.Leonardsen, E.Lindenberger, U.Madsen, K. S.Magnussen, F.Mowinckel, A. M.Nyberg, L.Roe, J. M.Segura, B.Sorensen, O.Suri, S.Zsoldos, E.AIBL,Walhovd, K. B.Fjell, A. M.2021-02-08doi:10.1101/2021.02.08.428915Cold Spring Harbor Laboratory Press2021-02-08
https://biorxiv.org/cgi/content/short/2021.01.22.427803v1?rss=1"
Roumazeilles, L.Schurz, M.Lojkiewiez, M.Verhagen, L.Schuffelgen, U.Marche, K.Mahmoodi, A.Emberton, A.Simpson, K.Joly, O.Khamassi, M.Rushworth, M. F.Mars, R. B.Sallet, J.2021-01-23doi:10.1101/2021.01.22.427803Cold Spring Harbor Laboratory Press2021-01-23
https://biorxiv.org/cgi/content/short/2021.02.19.431732v1?rss=1"
Patel, R.Mackay, C. E.Jansen, M. G.Devenyi, G.O'Donoghue, M. C.Kivimäki, M.Singh-Manoux, A.Zsoldos, E.Ebmeier, K. P.Chakravarty, M.Suri, S.2021-02-20doi:10.1101/2021.02.19.431732Cold Spring Harbor Laboratory Press2021-02-20
https://biorxiv.org/cgi/content/short/2021.02.23.432416v1?rss=1"
Vu Thi Ngoc, B.Ho Bich, H.Galazzo, G.Vu Tien Viet, D.Oomen, M.Nghiem Nguyen Minh, T.Tran Huy, H.Van Doorn, R.Wertheim, H. F.Penders, J.2021-02-23doi:10.1101/2021.02.23.432416Cold Spring Harbor Laboratory Press2021-02-23
https://biorxiv.org/cgi/content/short/2021.03.20.436248v1?rss=1"
Han, A. X.Felix Garza, Z. C.Welkers, M. R. A.Vigeveno, R. M.Tran, N. D.Le, T. Q. M.Pham, Q. T.Tran, T. N. A.Ha, M. T.Nguyen, T. H.Le, Q. T.Le, T. H.Hoang, T. B. N.Chokephaibulkit, K.Puthavathana, P.Nguyen, V. V. C.Nghiem, M. N.Tran, T. H.Wertheim, H. F. L.Horby, P.Fox, A.van Doorn, H. R.Eggink, D.de Jong, M. D.Russell, C. A.2021-03-20doi:10.1101/2021.03.20.436248Cold Spring Harbor Laboratory Press2021-03-20
https://biorxiv.org/cgi/content/short/2021.03.18.435948v1?rss=1"
Jackson, H.Menikou, S.Hamilton, S.McArdle, A.Shimizu, C.Galassini, R.Huang, H.Kim, J.Tremoulet, A.de Jonge, M.Kuijpers, T. W.Wright, V.Burns, J.Casals-Pascual, C.Herberg, J.Levin, M.Kaforou, M.The PERFORM Consortium,2021-03-19doi:10.1101/2021.03.18.435948Cold Spring Harbor Laboratory Press2021-03-19
https://biorxiv.org/cgi/content/short/2020.08.05.228700v1?rss=1"
Dimitrova, R.Arulkumaran, S.Carney, O.Chew, A.Falconer, S.Ciarrusta, J.Wolfers, T.Batalle, D.Cordero-Grande, L.Price, A. N.Teixeira, R. P.Hughes, E.Egloff, A.Hutter, J.Makropoulos, A.Robinson, E. C.Schuh, A.Vecchiato, K.Steinweg, J. K.Macleod, R.Marquand, A. F.McAlonan, G.Rutherford, M. A.Counsell, S. J.Smith, S. M.Rueckert, D.Hajnal, J. V.O'Muircheartaigh, J.Edwards, A. D.2020-08-05doi:10.1101/2020.08.05.228700Cold Spring Harbor Laboratory Press2020-08-05
https://biorxiv.org/cgi/content/short/2020.12.22.423823v1?rss=1"
Wray, J. P.Deltcheva, E. M.Boiers, C.Richardson, S. E.Chettri, J. B.Gagrica, S.Guo, Y.Illendula, A.Martens, J. H.Stunnenberg, H. H.Bushweller, J. H.Nimmo, R.Enver, T.2020-12-22doi:10.1101/2020.12.22.423823Cold Spring Harbor Laboratory Press2020-12-22
https://biorxiv.org/cgi/content/short/2021.02.01.429143v1?rss=1"
Nakua, H.Hawco, C.Forde, N. J.Jacobs, G. R.Joseph, M.Voineskos, A.Wheeler, A. L.Lai, M.-C.Szatmari, P.Kelley, E.Liu, X.Georgiades, S.Nicolson, R.Schachar, R.Crosbie, J.Anagnostou, E.Lerch, J. P.Arnold, P. D.Ameis, S. H.2021-02-02doi:10.1101/2021.02.01.429143Cold Spring Harbor Laboratory Press2021-02-02
https://biorxiv.org/cgi/content/short/2021.02.22.432227v1?rss=1"
Akam, T.Lustig, A.Rowland, J.Kapanaiah, S. K. T.Esteve-Agraz, J.Panniello, M.Marquez, C.Kohl, M.Kätzel, D.Costa, R. M.Walton, M. E.2021-02-23doi:10.1101/2021.02.22.432227Cold Spring Harbor Laboratory Press2021-02-23
https://biorxiv.org/cgi/content/short/2020.08.13.249813v1?rss=1"
Blokland, G. A.Grove, J.Chen, C.-Y.Cotsapas, C.Tobet, S.Handa, R.Schizophrenia Working Group of the Psychiatric Genomics Consortium,St Clair, D.Lencz, T.Mowry, B. J.Periyasamy, S.Cairns, M. J.Tooney, P. A.Wu, J. Q.Kelly, B.Kirov, G.Sullivan, P. F.Corvin, A.Riley, B. P.Esko, T.Milani, L.Jönsson, E. G.Palotie, A.Ehrenreich, H.Begemann, M.Steixner-Kumar, A.Sham, P. C.Iwata, N.Weinberger, D. R.Gejman, P. V.Sanders, A. R.Buxbaum, J. D.Rujescu, D.Giegling, I.Konte, B.Hartmann, A. M.Bramon, E.Murray, R. M.Pato, M. T.Lee,2020-08-17doi:10.1101/2020.08.13.249813Cold Spring Harbor Laboratory Press2020-08-17
https://biorxiv.org/cgi/content/short/2021.04.27.441137v1?rss=1"
TpG mutations, resembling mutational signature SBS1. MBD4-deficient adenomas harbour mutations in known CRC driver genes, although AMER1 mutations were more common and KRAS mutations less frequent. We did not find an increased risk for colorectal tumours in individuals with a monoallelic MBD4 LOF variant. We suggest that this condition should be termed MBD4-associated neoplasia syndrome (MANS) and that MBD4 is included in testing for the genetic diagnosis of polyposis and/or early-onset AML.
]]>Palles, C.Chew, E.Grolleman, J. E.Galavotti, S.Flensburg, C.Jansen, E. A. M.Curley, H.Chegwidden, L.Arbe Barnes, E.Bajel, A.Sherwood, K.Martin, L.Thomas, H.Georgiou, D.Fostira, F.Goldberg, Y.Adams, D.van der Biezen, S.Christie, M.Clendenning, M.Deltas, C.Dimovski, A. J.Dymerska, D.Lubinski, J.Mahmood, K.van der Post, R. S.Sanders, M.Weitz, J.Taylor, J. C.Turnbull, C.Vreede, L.van Wezel, T.Whalley, C.Arnedo Pac, C.Caravagna, G.Cross, W.Chubb, D.Frangou, A.Gruber, A.Kinnersley, B.Noyvert, B.Church, D.Graham, T.2021-04-28doi:10.1101/2021.04.27.441137Cold Spring Harbor Laboratory Press2021-04-28
https://biorxiv.org/cgi/content/short/2021.04.05.438429v1?rss=1"
Fraza, C.Dinga, R.Beckmann, C. F.Marquand, A. F.2021-04-06doi:10.1101/2021.04.05.438429Cold Spring Harbor Laboratory Press2021-04-06
https://biorxiv.org/cgi/content/short/2021.04.16.440223v1?rss=1"
Yendiki, A.Aggarwal, M.Axer, M.Howard, A. F.van Cappellen van Walsum, A.-M.Haber, S. N.2021-04-19doi:10.1101/2021.04.16.440223Cold Spring Harbor Laboratory Press2021-04-19
https://biorxiv.org/cgi/content/short/2021.05.05.442735v1?rss=1"
Sha, Z.Rooij, D. v.Anagnostou, E.Arango, C.Auzias, G.Behrmann, M.Bernhardt, B.Bolte, S.Busatto, G. F.Calderoni, S.Calvo, R.Daly, E.Deruelle, C.Duan, M.Duran, F. L. S.Durston, S.Ecker, C.Ehrlich, S.Fair, D.Fedor, J.Fitzgerald, J.Floris, D. L.Franke, B.Freitag, C. M.Gallagher, L.Glahn, D. C.Haar, S.Hoekstra, L.Jahanshad, N.Jalbrzikowski, M.Janssen, J.King, J. A.Lazaro, L.Luna, B.McGrath, J.Medland, S. E.Molloy, C.Muratori, F.Murphy, D. G. M.Neufeld, J.O'Hearn, K.Oranje, B.Parellada, M.Pariente, J.Postema, M.2021-05-06doi:10.1101/2021.05.05.442735Cold Spring Harbor Laboratory Press2021-05-06
https://biorxiv.org/cgi/content/short/2021.05.12.443095v1?rss=1"
van Deuren, R. C.Andersson-Assarsson, J. C.Kristensson, F. M.Steehouwer, M.Sjöholm, K.Svensson, P.-A.Peterse, M.Gilissen, C.Taube, M.Jacobson, P.Perkins, R.Brunner, H. G.Netea, M. G.Peltonen, M.Carlsson, B.Hoischen, A.Carlsson, L. M.2021-05-13doi:10.1101/2021.05.12.443095Cold Spring Harbor Laboratory Press2021-05-13
https://biorxiv.org/cgi/content/short/2021.04.30.442229v1?rss=1"
Kilic, G.Bulut, O.Jaeger, M.ter Horst, R.Koeken, V.Moorlag, S. J. C. F. M.Mourits, V.de Bree, C.Dominguez-Andres, J.Joosten, L. A. B.Netea, M.2021-05-04doi:10.1101/2021.04.30.442229Cold Spring Harbor Laboratory Press2021-05-04
https://biorxiv.org/cgi/content/short/2021.04.30.442117v1?rss=1"
Park, B.-y.Lariviere, S.Rodriguez-Cruces, R.Royer, J.Tavakol, S.Wang, Y.Caciagli, L.Caligiuri, M. E.Gambardella, A.Concha, L.Keller, S. S.Cendes, F.Alvim, M. K.Yasuda, C.Bonilha, L.Gleichgerrcht, E.Focke, N. K.Kreilkamp, B. A.Domin, M.von Podewils, F.Langner, S.Rummel, C.Rebsamen, M.Wiest, R.Martin, P.Kotikalapudi, R.Bender, B.O'Brien, T. J.Law, M.Sinclair, B.Vivash, L.Desmond, P. M.Malpas, C. B.Lui, E.Alhusaini, S.Doherty, C. P.Cavalleri, G. L.Delanty, N.Kalviainen, R.Jackson, G. D.Kowalczyk, M.Mascalchi, M.Se2021-04-30doi:10.1101/2021.04.30.442117Cold Spring Harbor Laboratory Press2021-04-30
https://biorxiv.org/cgi/content/short/2020.09.24.311654v1?rss=1"
Damatac, C. G.Leenders, A. E. M.Soheili-Nezhad, S.Chauvin, R. J. M.Mennes, M. J. J.Zwiers, M. P.van Rooij, D.Akkermans, S. E. A.Naaijen, J.Franke, B.Buitelaar, J. K.Beckmann, C. F.Sprooten, E.2020-09-25doi:10.1101/2020.09.24.311654Cold Spring Harbor Laboratory Press2020-09-25
https://biorxiv.org/cgi/content/short/2021.05.31.445808v1?rss=1"
Ardesch, D. J.Scholtens, L. H.de Lange, S. C.Roumazeilles, L.Khrapitchev, A. A.Preuss, T. M.Rilling, J. K.Mars, R. B.van den Heuvel, M. P.2021-05-31doi:10.1101/2021.05.31.445808Cold Spring Harbor Laboratory Press2021-05-31
https://biorxiv.org/cgi/content/short/2021.05.28.446120v1?rss=1"
Kia, S. M.Huijsdens, H.Rutherford, S.Dinga, R.Wolfers, T.Mennes, M.Andreassen, O.Westlye, L. T.Beckmann, C. F.Marquand, A. F.2021-05-30doi:10.1101/2021.05.28.446120Cold Spring Harbor Laboratory Press2021-05-30
https://biorxiv.org/cgi/content/short/2021.05.20.444828v1?rss=1"
Dennis, J.Tyrer, J. P.Walker, L. C.Michailidou, K.Dorling, L.Bolla, M. K.Wang, Q.Ahearn, T. U.Andrulis, I. L.Anton-Culver, H.Antonenkova, N. N.Arndt, V.Aronson, K. J.Beane Freeman, L. E.Beckmann, M. W.Behrens, S.Benitez, J.Bermisheva, M.Bogdanova, N. V.Bojesen, S. E.Brenner, H.Castelao, J. E.Chang-Claude, J.Chenevix-Trench, G.Clarke, C. L.Collaborators, N.Collee, J. M.Consortium, C.Couch, F. J.Cox, A.Cross, S. S.Czene, K.Devilee, P.Dork, T.Dossus, L.Eliassen, A. H.Eriksson, M.Evans, D. G.Fasching, P. A.Figueroa, J.2021-05-21doi:10.1101/2021.05.20.444828Cold Spring Harbor Laboratory Press2021-05-21
https://biorxiv.org/cgi/content/short/2021.05.29.445691v1?rss=1"
View larger version (67K):
org.highwire.dtl.DTLVardef@100f3aorg.highwire.dtl.DTLVardef@57adfforg.highwire.dtl.DTLVardef@6052fcorg.highwire.dtl.DTLVardef@1e85c21_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIBead Supported Lipid Bilayers (BSLB) reconstituting antigen-presenting cells support synapse assembly by T cells and the release of effector particles.
C_LIO_LIBSLB facilitate the dissection of the cellular machineries and synapse composition shaping the released tSV.
C_LIO_LItSV and their steadily released counterparts have a different composition. TSV show a higher enrichment of effectors including immune receptors, miR, RNA- and other nucleic acid-binding proteins, than EVs.
C_LI
]]>Cespedes, P. F.Jainarayanan, A. K.Fernandez-Messina, L.Valvo, S.Saliba, D. G.Kvalvaag, A.Kurz, E.Colin-York, H.Fritzsche, M.Yanchun, P.Dong, T.Siller-Farfan, J. A.Dushek, O.Maj, M.Sezgin, E.Peacock, B.Law, A.Aubert, D.Engledow, S.Attar, M.Sanchez-Madrid, F.Hester, S.Fisher, R.Dustin, M. L.2021-05-29doi:10.1101/2021.05.29.445691Cold Spring Harbor Laboratory Press2021-05-29
https://biorxiv.org/cgi/content/short/2021.05.25.445571v1?rss=1"
Galiani, S.Reglinski, K.Carravilla, P.Barbotin, A.Urbancic, I.Ott, J.Sehr, J.Sezgin, E.Schneider, F.Waithe, D.Hublitz, P.Schliebs, W.Erdmann, R.Eggeling, C.2021-05-26doi:10.1101/2021.05.25.445571Cold Spring Harbor Laboratory Press2021-05-26
https://biorxiv.org/cgi/content/short/2021.06.16.448390v1?rss=1"
Norgaard, M.Matheson, G. J.Hansen, H. D.Thomas, A. G.Searle, G.Rizzo, G.Veronese, M.Giacomel, A.Yaqub, M.Tonietto, M.Funck, T.Gillman, A.Boniface, H.Routier, A.Dalenberg, J. R.Betthauser, T.Feingold, F.Markiewicz, C. J.Gorgolewski, K. J.Blair, R. W.Appelhoff, S.Gau, R.Salo, T.Niso, G.Pernet, C.Phillips, C.Oostenveld, R.Carson, R. E.Gallezot, J.-D.Knudsen, G. M.Innis, R. B.Ganz, M.2021-06-17doi:10.1101/2021.06.16.448390Cold Spring Harbor Laboratory Press2021-06-17
https://biorxiv.org/cgi/content/short/2021.06.21.449154v1?rss=1"
Tendler, B. C.Hanayik, T.Ansorge, O.Bangerter-Christensen, S.Berns, G. S.Bertelsen, M. F.Bryant, K. L.Foxley, S.Howard, A. F. D.Huszar, I.Khrapitchev, A. A.Leonte, A.Manger, P. R.Menke, R. A. L.Mollink, J.Mortimer, D.Pallebage-Gamarallage, M.Roumazeilles, L.Sallet, J.Scott, C.Smart, A.Turner, M. R.Wang, C.Jbabdi, S.Mars, R. B.Miller, K. L.2021-06-22doi:10.1101/2021.06.21.449154Cold Spring Harbor Laboratory Press2021-06-22
https://biorxiv.org/cgi/content/short/2020.12.15.422826v1?rss=1"
Lazari, A.Salvan, P.Cottaar, M.Papp, D.van der Werf, O. J.Johnstone, A.Sanders, Z.-B.Sampaio-Baptista, C.Eichert, N.Miyamoto, K.Winkler, A.Callaghan, M. F.Nichols, T. E.Stagg, C. J.Rushworth, M.Verhagen, L.Johansen-Berg, H.2020-12-15doi:10.1101/2020.12.15.422826Cold Spring Harbor Laboratory Press2020-12-15
https://biorxiv.org/cgi/content/short/2021.06.25.449953v1?rss=1"
Agudelo, L. Z.Tuyeras, R. V.Llinares, C.Morcuende, A.Park, Y.Sun, N.Kuosmanen, S. M.Atabaki-Pasdar, N.Ho, L.-L.Galani, K.Franks, P. W.Kutlu, B.Grove, K.Femenia, T.Kellis, M.2021-06-27doi:10.1101/2021.06.25.449953Cold Spring Harbor Laboratory Press2021-06-27
https://biorxiv.org/cgi/content/short/2021.06.05.446432v1?rss=1"
Carravilla, P.Dasgupta, A.Zhurgenbayeva, G.Danylchuk, D. I.Klymchenko, A. S.Sezgin, E.Eggeling, C.2021-06-05doi:10.1101/2021.06.05.446432Cold Spring Harbor Laboratory Press2021-06-05
https://biorxiv.org/cgi/content/short/2021.06.09.447672v1?rss=1"
Strindberg, M.Fransson, P.Cabral, J.Aden, U.2021-06-09doi:10.1101/2021.06.09.447672Cold Spring Harbor Laboratory Press2021-06-09
https://biorxiv.org/cgi/content/short/2021.06.08.447489v1?rss=1"
Bethlehem, R. A. I.Seidlitz, J.White, S. R.Vogel, J. W.Anderson, K. M.Adamson, C.Adler, S.Alexopoulos, G. S.Anagnostou, E.Areces-Gonzalez, A.Astle, D. E.Auyeung, B.Ayub, M.Ball, G.Baron-Cohen, S.Beare, R.Bedford, S. A.Benegal, V.Beyer, F.Bin Bae, J.Blangero, J.Blesa Cabez, M.Boardman, J. P.Borzage, M.Bosch-Bayard, J. F.Bourke, N.Calhoun, V. D.Chakravarty, M. M.Chen, C.Chertavian, C.Chetelat, G.Chong, Y. S.Cole, J. H.Corvin, A.Courchesne, E.Crivello, F.Cropley, V. L.Crosbie, J.Crossley, N.Delarue, M.Desrivieres, S.2021-06-10doi:10.1101/2021.06.08.447489Cold Spring Harbor Laboratory Press2021-06-10
https://biorxiv.org/cgi/content/short/2021.08.08.455487v1?rss=1"
Rutherford, S.Fraza, C.Dinga, R.Kia, S. M.Wolfers, T.Zabihi, M.Berthet, P.Worker, A.Verdi, S.Andrews, D.Han, L.Bayer, J.Dazzan, P.McGuire, P.Mocking, R. T.Schene, A.Sripada, C.Tso, I. F.Duval, E. R.Chang, S.-E.Pennix, B. W.Heitzeg, M. M.Burt, S. A.Hyde, L.Amaral, D.Nordahl, C. W.Andreasssen, O. A.Westlye, L. T.Zahn, R.Ruhe, H. G.Beckmann, C.Marquand, A. F.2021-08-08doi:10.1101/2021.08.08.455487Cold Spring Harbor Laboratory Press2021-08-08
https://biorxiv.org/cgi/content/short/2021.08.08.455583v1?rss=1"
Rutherford, S.Kia, S. M.Wolfers, T.Fraza, C.Zabihi, M.Dinga, R.Berthet, P.Worker, A.Verdi, S.Ruhe, H. G.Beckmann, C. F.Marquand, A. F.2021-08-10doi:10.1101/2021.08.08.455583Cold Spring Harbor Laboratory Press2021-08-10
https://biorxiv.org/cgi/content/short/2021.07.27.453965v1?rss=1"
Alonso Martinez, S.Llera Arenas, A.Ter Horst, G. T.Vidaurre, D.2021-07-27doi:10.1101/2021.07.27.453965Cold Spring Harbor Laboratory Press2021-07-27
https://biorxiv.org/cgi/content/short/2021.08.15.456225v1?rss=1"
Stratoulias, V.Ruiz, R.Kanatani, S.Osman, A. M.Armengol, J. A.Rodriguez-Moreno, A.Murgoci, A.-N.Garcia-Dominguez, I.Keane, L.Vazquez-Carbera, G.Alonso-Bellido, I.Vernoux, N.Tejera, D.Grabert, K.Cheray, M.Gonzalez-Rodriguez, P.Perez-Villegas, E. M.Martinez-Gallego, I.Brodin, D.Avila-Carino, J.Airavaara, M.Uhlen, P.Heneka, M. T.Tremblay, M.-E.Blomgren, K.Venero, J. L.Joseph, B.2021-08-16doi:10.1101/2021.08.15.456225Cold Spring Harbor Laboratory Press2021-08-16
https://biorxiv.org/cgi/content/short/2021.07.12.452018v1?rss=1"
120 000 regions across multiple organs, in benign and malignant tissues. We demonstrate that genome-wide copy number variation reveals distinct clonal patterns within tumours and in nearby benign tissue. Our results suggest a model for how genomic instability arises in histologically benign tissue that may represent early events in cancer evolution. We highlight the power of an unsupervised approach to capture the molecular and spatial continuums in a tissue context and challenge the rationale for treatment paradigms, including focal therapy.
]]>Erickson, A.Berglund, E.He, M.Marklund, M.Mirzazadeh, R.Schultz, N.Bergenstrahle, L.Kvastad, L.Andersson, A.Bergenstrahle, J.Larsson, L.Shamikh, A.Basmaci, E.de Stahl, T. D.Rajakumar, T.Thrane, K.Ji, A. L.Khavari, P. A.Tarish, F.Tanoglidi, A.Maaskola, J.Colling, R.Mirtti, T.Hamdy, F. C.Woodcock, D. J.Helleday, T.Mills, I. G.Lamb, A. D.Lundeberg, J.2021-07-12doi:10.1101/2021.07.12.452018Cold Spring Harbor Laboratory Press2021-07-12
https://biorxiv.org/cgi/content/short/2021.08.24.457538v1?rss=1"
Shafiei, G.Bazinet, V.Dadar, M.Manera, A. L.Collins, D. L.Dagher, A.Borroni, B.Sanchez-Valle, R.Moreno, F.Laforce, R.Graff, C.Synofzik, M.Galimberti, D.Rowe, J. B.Masellis, M.Tartaglia, M. C.Finger, E.Vandenberghe, R.de Mendonca, A.Tagliavini, F.Santana, I.Butler, C.Gerhard, A.Danek, A.Levin, J.Otto, M.Sorbi, S.Jiskoot, L. C.Seelaar, H.van Swieten, J. C.Rohrer, J. D.Misic, B.Ducharme, S.Frontotemporal Lobar Degeneration Neuroimaging Initiative (FTLDNI),GENetic Frontotemporal dementia Initiative (GENFI),2021-08-26doi:10.1101/2021.08.24.457538Cold Spring Harbor Laboratory Press2021-08-26
https://biorxiv.org/cgi/content/short/2021.08.08.455573v1?rss=1"
Williams, R.Lukoseviciute, M.Sauka-Spengler, T.Bronner, M. E.2021-08-08doi:10.1101/2021.08.08.455573Cold Spring Harbor Laboratory Press2021-08-08
https://biorxiv.org/cgi/content/short/2021.02.10.430513v1?rss=1"
Lukoseviciute, M.Mayes, S.Sauka-Spengler, T.2021-02-10doi:10.1101/2021.02.10.430513Cold Spring Harbor Laboratory Press2021-02-10
https://biorxiv.org/cgi/content/short/2021.08.09.454869v1?rss=1"
Baranasic, D.Hoertenhuber, M.Balwierz, P.Zehnder, T.Mukarram, A. K.Nepal, C.Varnai, C.Hadzhiev, Y.Jimenez-Gonzalez, A.Li, N.Wragg, J. W.D'Orazio, F.Diaz, N.Hernandez-Rodriguez, B.Chen, Z.Stoiber, M.Dong, M.Stevens, I.Ross, S. E.Eagle, A.Martin, R.Obasaju, P.Rastegar, S.McGarvey, A. C.Kopp, W.Chambers, E.Wang, D.Kim, H. K.Acemel, R. D.Naranjo, S.Lapinski, M.Chong-Morrison, V.Mathavan, S.Peers, B.Sauka-Spengler, T.Vingron, M.Carninci, P.Ohler, U.Lacadie, S. A.Burgess, S.Winata, C.van Eeden, F.Vaquerizas, J. M.G2021-08-09doi:10.1101/2021.08.09.454869Cold Spring Harbor Laboratory Press2021-08-09
https://biorxiv.org/cgi/content/short/2021.09.23.461002v1?rss=1"
Mediano, P.Ikkala, A.Kievit, R. A.Jagannathan, S. R.Varley, T. F.Stamatakis, E. A.Bekinschtein, T. A.Bor, D.2021-09-23doi:10.1101/2021.09.23.461002Cold Spring Harbor Laboratory Press2021-09-23
https://biorxiv.org/cgi/content/short/2021.09.16.458157v1?rss=1"
Maynard, D. S.Bialic-Murphy, L.Zohner, C. M.Averill, C.van den Hoogen, J.Ma, H.Mo, L.Smith, G. R.Aubin, I.Berenguer, E.Boonman, C. C. F.Catford, J.Cerabolini, B. E. L.Dias, A.Gonzalez-Melo, A.Heitz, P.Lusk, C. H.Mori, A. S.Niinemets, U.Pillar, V. D.Rosell, J. A.Schurr, F. M.Sheremetev, S. N.da Silva, A. C.Sosinski, E.van Bodegom, P. M.Weiher, E.Bönisch, G.Kattge, J.Crowther, T. W.2021-09-17doi:10.1101/2021.09.16.458157Cold Spring Harbor Laboratory Press2021-09-17
https://biorxiv.org/cgi/content/short/2021.09.03.458926v1?rss=1"
Gong, W.Bai, S.Zheng, Y.-Q.Beckmann, C.Smith, S. M.2021-09-06doi:10.1101/2021.09.03.458926Cold Spring Harbor Laboratory Press2021-09-06
https://biorxiv.org/cgi/content/short/2021.09.02.458694v1?rss=1"
Reveley, C.Ye, F. Q.Mars, R. B.Leopold, D. A.2021-09-02doi:10.1101/2021.09.02.458694Cold Spring Harbor Laboratory Press2021-09-02
https://biorxiv.org/cgi/content/short/2021.11.18.469069v1?rss=1"
Vinding, M. C.Oostenveld, R.2021-11-19doi:10.1101/2021.11.18.469069Cold Spring Harbor Laboratory Press2021-11-19
https://biorxiv.org/cgi/content/short/2020.04.24.031138v1?rss=1"
Brouwer, R. M.Klein, M.Grasby, K. L.Schnack, H. G.Jahanshad, N.Teeuw, J.Thomopoulos, S. I.Sprooten, E.Franz, C. E.Gogtay, N.Kremen, W.Panizzon, M. S.Olde Loohuis, L. M.Whelan, C. D.Aghajani, M.Alloza, C.Alnaes, D.Artiges, E.Ayesa-Arriola, R.Barker, G. J.Blok, E.Boen, E.Breukelaar, I. A.Bright, J. K.Buimer, E. E.Bülow, R.Cannon, D. M.Ciufolini, S.Crossley, N. A.Damatac, C. G.Dazzan, P.de Mol, C. L.de Zwarte, S. M.Desrivieres, S.Diaz-Caneja, C. M.Doan, N. T.Dohm, K.Fröhner, J. H.Goltermann, J.Grigis, A.Grotegerd, D2020-04-27doi:10.1101/2020.04.24.031138Cold Spring Harbor Laboratory Press2020-04-27
https://biorxiv.org/cgi/content/short/2021.11.04.466897v1?rss=1"
Eising, E.Mirza-Schreiber, N.de Zeeuw, E. L.Wang, C. A.Truong, D. T.Allegrini, A. G.Shapland, C. Y.Zhu, G.Wigg, K. G.Gerritse, M.Molz, B.Alagoz, G.Gialluisi, A.Abbondanza, F.Rimfeld, K.Van Donkelaar, M. M.Liao, Z.Jansen, P. R.Andlauer, T. F. M.Bates, T. C.Bernard, M.Blokland, K.Borglum, A. D.Bourgeron, T.Brandeis, D.Ceroni, F.Dale, P. S.de Jong, P. F.DeFries, J. C.Demontis, D.Feng, Y.Gordon, S. D.Guger, S. L.Hayiou-Thomas, M. E.Hernandez-Cabrera, J. A.Hottenga, J.- J.Hulme, C.Kerr, E. N.Koomar, T.Landerl, K.Lovett,2021-11-04doi:10.1101/2021.11.04.466897Cold Spring Harbor Laboratory Press2021-11-04
https://biorxiv.org/cgi/content/short/2021.11.02.466974v1?rss=1"
Kliza, K. W.Song, W.Pinzuti, I.Schaubeck, S.Kunzelmann, S.Kuntin, D.Fornili, A.Pandini, A.Hofmann, K.Garnett, J.Stieglitz, B.Husnjak, K.2021-11-02doi:10.1101/2021.11.02.466974Cold Spring Harbor Laboratory Press2021-11-02
https://biorxiv.org/cgi/content/short/2021.11.15.468619v1?rss=1"
Wedemann, L.Gurdap, C. O.Sych, T.Sezgin, E.2021-11-16doi:10.1101/2021.11.15.468619Cold Spring Harbor Laboratory Press2021-11-16
https://biorxiv.org/cgi/content/short/2021.11.12.468429v1?rss=1"
Bussy, A.Levy, J.Patel, R.Cupo, L.Best, T.Van Langenhove, T.Nielsen, J.Pijnenburg, Y.Landqvist Waldö, M.Remes, A.Schroeter, M. L.Santana, I.Pasquier, F.Otto, M.Danek, A.Levin, J.Le Ber, I.Vandenberghe, R.Synofzik, M.Moreno, F.de Mendonca, A.Sanchez-Valle, R.Laforce, R.Langheinrich, T.Gerhard, A.Graff, C.Butler, C. R.Sorbi, S.Jiskoot, L.Seelaar, H.van Swieten, J. C.Finger, E.Tartaglia, M. C.Masellis, M.Tiraboschi, P.Galimberti, D.Borroni, B.Rowe, J.Bocchetta, M.Rohrer, J. D.Devenyi, G. A.Chakravarty, M. M.Ducha2021-11-16doi:10.1101/2021.11.12.468429Cold Spring Harbor Laboratory Press2021-11-16
https://biorxiv.org/cgi/content/short/2021.10.19.462578v1?rss=1"
Tielbeek, J. J.Uffelmann, E.Williams, B. S.Colodro-Conde, L.Gagnon, E.Mallard, T. T.Levitt, B. E.Jansen, P. R.Johansson, A.Sallis, H. M.Pistis, G.Saunders, G. R.Allegrini, A. G.Rimfeld, K.Konte, B.Klein, M.Hartmann, A. M.Salvatore, J. E.Nolte, I. M.Demontis, D.Malmberg, A.Burt, S. A.Savage, J. E.Sugden, K.Poulton, R.Harris, K. M.Vrieze, S.McGue, M.Iacono, W. G.Mota, N. R.Mill, J.Viana, J. F.Mitchell, B. L.Morosoli, J. J.Andlauer, T. F. M.Ouellet-Morin, I.Tremblay, R. E.Cote, S. M.Gouin, J.-P.Brendgen, M. R.Dionne,2021-10-20doi:10.1101/2021.10.19.462578Cold Spring Harbor Laboratory Press2021-10-20
https://biorxiv.org/cgi/content/short/2020.10.29.339317v1?rss=1"
18,000 designs), crystallographic data (>840 ligand-bound X-ray structures), assay data (>10,000 measurements), and synthesized molecules (>2,400 compounds) for this campaign were shared rapidly and openly, creating a rich open and IP-free knowledgebase for future anti-coronavirus drug discovery.
]]>The COVID Moonshot Consortium,Achdout, H.Aimon, A.Bar-David, E.Barr, H.Ben-Shmuel, A.Bennett, J.Bobby, M. L.Brun, J.BVNBS, S.Calmiano, M.Carbery, A.Cattermole, E.Chodera, J. D.Clyde, A.Coffland, J. E.Cohen, G.Cole, J.Contini, A.Cox, L.Cvitkovic, M.Dias, A.Douangamath, A.Duberstein, S.Dudgeon, T.Dunnett, L.Eastman, P. K.Erez, N.Fairhead, M.Fearon, D.Fedorov, O.Ferla, M.Foster, H.Foster, R.Gabizon, R.Gehrtz, P.Gileadi, C.Giroud, C.Glass, W. G.Glen, R.Glinert, I.Gorichko, M.Gorrie-Stone, T.Griffen, E. J.Heer2020-10-30doi:10.1101/2020.10.29.339317Cold Spring Harbor Laboratory Press2020-10-30