bioRxiv Channel: Somatic Cell Genome Editing Program https://biorxiv.org This feed contains articles for bioRxiv Channel "Somatic Cell Genome Editing Program" bioRxiv bioRxiv https://biorxiv.org <![CDATA[ Efficient Homology-directed Repair with Circular ssDNA Donors ]]> https://biorxiv.org/cgi/content/short/864199v1?rss=1" Iyer, S. Mir, A. Ibraheim, R. Lee, J. VegaBadillo, J. Roscoe, B. Zhu, L. J. Liu, P. Luk, K. Mintzer, E. de Brito, J. S. Zamore, P. Sontheimer, E. J. Wolfe, S. 2019-12-05 doi:10.1101/864199 Cold Spring Harbor Laboratory Press 2019-12-05 <![CDATA[ Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP.B capsids ]]> https://biorxiv.org/cgi/content/short/538421v1?rss=1" Huang, Q. Chan, K. Y. Tobey, I. G. Chan, Y. A. Poterba, T. Boutros, C. L. Balazs, A. B. Daneman, R. Bloom, J. M. Seed, C. Deverman, B. E. 2019-02-01 doi:10.1101/538421 Cold Spring Harbor Laboratory Press 2019-02-01 <![CDATA[ Methods Matter -- Standard Production Platforms For Recombinant AAV Can Produce Chemically And Functionally Distinct Vectors ]]> https://biorxiv.org/cgi/content/short/640169v1?rss=1" Rumachik, N. G. Malaker, S. A. Poweleit, N. Maynard, L. H. Adams, C. M. Leib, R. D. Cirolia, G. Thomas, D. Stamnes, S. Holt, K. Sinn, P. May, A. P. Paulk, N. K. 2019-05-17 doi:10.1101/640169 Cold Spring Harbor Laboratory Press 2019-05-17 <![CDATA[ Precision Cas9 Genome Editing in vivo with All-in-one, Self-targeting AAV Vectors ]]> https://biorxiv.org/cgi/content/short/2020.10.09.333997v1?rss=1" Ibraheim, R. Tai, P. W. L. Mir, A. Javeed, N. Wang, J. Rodriguez, T. C. Nelson, S. Khokhar, E. Mintzer, E. Maitland, S. Cao, Y. Tsagkaraki, E. Wolfe, S. A. Wang, D. Pai, A. A. Xue, W. Gao, G. Sontheimer, E. J. 2020-10-09 doi:10.1101/2020.10.09.333997 Cold Spring Harbor Laboratory Press 2020-10-09 <![CDATA[ Genome-wide annotation of gene regulatory elements linked to cell fitness ]]> https://biorxiv.org/cgi/content/short/2021.03.08.434470v1?rss=1" Klann, T. Barrera, A. Ettyreddy, A. Rickels, R. Bryois, J. Jiang, S. Adkar, S. Iglesias, N. Sullivan, P. Reddy, T. E. Crawford, G. E. Gersbach, C. 2021-03-09 doi:10.1101/2021.03.08.434470 Cold Spring Harbor Laboratory Press 2021-03-09 <![CDATA[ Transgenic mice for in vivo epigenome editing with CRISPR-based systems ]]> https://biorxiv.org/cgi/content/short/2021.03.08.434430v1?rss=1" Gemberling, M. Siklenka, K. Rodriguez, E. Eisinger, K. Barrera, A. Liu, F. Kantor, A. Li, L. Cigliola, V. Hazlett, M. Williams, C. Bartelt, L. Bodle, J. Daniels, H. Rouse, C. Hilton, I. Madigan, V. Asokan, A. Ciofani, M. Poss, K. Reddy, T. E. West, A. Gersbach, C. 2021-03-08 doi:10.1101/2021.03.08.434430 Cold Spring Harbor Laboratory Press 2021-03-08 <![CDATA[ 5′ Modifications Improve Potency and Efficacy of DNA Donors for Precision Genome Editing ]]> https://biorxiv.org/cgi/content/short/354480v1?rss=1" Ghanta, K. S. Dokshin, G. A. Mir, A. Krishnamurthy, P. M. Gneid, H. Edraki, A. Watts, J. K. Sontheimer, E. J. Mello, C. C. 2018-06-22 doi:10.1101/354480 Cold Spring Harbor Laboratory Press 2018-06-22 <![CDATA[ Improved prime editors enable pathogenic allele correction and cancer modelling in adult mice ]]> https://biorxiv.org/cgi/content/short/2020.12.15.422970v1?rss=1" Liu, P. Liang, S. Zheng, C. Mintzer, E. Zhao, Y. G. Ponnienselvan, K. Mir, A. Sontheimer, E. J. Gao, G. Flotte, T. R. Wolfe, S. Xue, W. 2020-12-16 doi:10.1101/2020.12.15.422970 Cold Spring Harbor Laboratory Press 2020-12-16 <![CDATA[ Diverse ATPase proteins in mobilomes constitute a large potential sink for prokaryotic host ATP ]]> https://biorxiv.org/cgi/content/short/2021.04.01.438130v1?rss=1" Shim, H. Shivram, H. Lei, S. Doudna, J. A. Banfield, J. 2021-04-01 doi:10.1101/2021.04.01.438130 Cold Spring Harbor Laboratory Press 2021-04-01 <![CDATA[ The FusX TALE Base Editor (FusXTBE) for rapid mitochondrial DNA programming of human cells in vitro and zebrafish disease models in vivo ]]> https://biorxiv.org/cgi/content/short/2021.05.18.444740v1?rss=1" Sabharwal, A. Kar, B. Castillo, S. R. Holmberg, S. R. Kendall, B. L. Cotter, R. P. WareJoncas, Z. Clark, K. J. Ekker, S. C. 2021-05-20 doi:10.1101/2021.05.18.444740 Cold Spring Harbor Laboratory Press 2021-05-20 <![CDATA[ Self-delivering CRISPR RNAs for AAV Co-delivery and Genome Editing in vivo ]]> https://biorxiv.org/cgi/content/short/2023.03.20.533459v1?rss=1" Zhang, H. Kelly, K. Lee, J. Echeverria, D. Cooper, D. Panwala, R. Chen, Z. Gaston, N. Newby, G. A. Xie, J. Liu, D. R. Gao, G. Wolfe, S. A. Khvorova, A. Watts, J. K. Sontheimer, E. J. 2023-03-20 doi:10.1101/2023.03.20.533459 Cold Spring Harbor Laboratory Press 2023-03-20 <![CDATA[ Orthogonal CRISPR screens to identify transcriptional and epigenetic regulators of human CD8 T cell function ]]> https://biorxiv.org/cgi/content/short/2023.05.01.538906v1?rss=1" McCutcheon, S. Swartz, A. Brown, M. Barrera, A. McRoberts Amador, C. Siklenka, K. Humayun, L. Isaacs, J. Reddy, T. E. Nair, S. Antonia, S. Gersbach, C. A. 2023-05-01 doi:10.1101/2023.05.01.538906 Cold Spring Harbor Laboratory Press 2023-05-01