bioRxiv Channel: University of Geneva https://biorxiv.org This feed contains articles for bioRxiv Channel "University of Geneva" bioRxiv bioRxiv https://biorxiv.org <![CDATA[ Quantitative analysis of food web dynamics in a low export ecosystem ]]> https://biorxiv.org/content/10.1101/2023.03.17.532807v1?rss=1 McNair, H. M. Meyer, M. G. Lerch, S. J. Maas, A. E. Stephens, B. M. Fox, J. Buck, K. N. Burns, S. M. Cetinic, I. Cohn, M. R. Durkin, C. Gifford, S. M. Gong, W. Graff, J. R. Jenkins, B. Jones, E. L. Santoro, A. E. Shea, C. H. Stamieszkin, K. Steinberg, D. K. Marchetti, A. Carlson, C. A. Menden-Deuer, S. Brzezinski, M. A. Siegel, D. A. Rynearson, T. A. 2023-03-22 doi:10.1101/2023.03.17.532807 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Comparison of genomic-enabled cross selection criteria for the improvement of inbred line breeding populations ]]> https://biorxiv.org/content/10.1101/2023.03.17.533166v1?rss=1 Danguy des Deserts, A. Durand, N. Servin, B. Goudemand-Duge, E. Alliot, J.-M. Ruiz, D. Charmet, G. Elsen, J.-M. Bouchet, S. 2023-03-22 doi:10.1101/2023.03.17.533166 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Genetic dysregulation of an endothelial Ras signaling network in vein of Galen malformations ]]> https://biorxiv.org/content/10.1101/2023.03.18.532837v1?rss=1 Zhao, S. Mekbib, K. Y. van der Ent, M. A. Allington, G. Prendergast, A. Chau, J. E. Smith, H. Shohfi, J. Ocken, J. Duran, D. Furey, C. G. Le, H. T. Duy, P. Q. Reeves, B. C. Zhang, J. Nelson-Williams, C. Chen, D. Li, B. Nottoli, T. Bai, S. Rolle, M. Zeng, X. Dong, W. Fu, P.-Y. Wang, Y.-C. Mane, S. Piwowarczyk, P. Fehnel, K. P. See, A. P. Iskandar, B. J. Aagaard-Kienitz, B. Kundishora, A. J. DeSpenza, T. Greenberg, A. B. W. Kidanemariam, S. M. Prendergast, A. Johnston, J. M. Jackson, E. Storm, P. B. Lang, S.-S. Butler, W. E. Carter, B. S. Chapman, P. St 2023-03-22 doi:10.1101/2023.03.18.532837 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Pharmacologically targeting KRASG12D in PDAC models:tumor cell intrinsic and extrinsic impact ]]> https://biorxiv.org/content/10.1101/2023.03.18.533261v1?rss=1 Kumarasamy, V. Frangou, C. Wang, J. Wan, Y. Dynka, A. Rosenheck, H. Dey, P. Abel, E. V. Knudsen, E. Witkiewicz, A. 2023-03-22 doi:10.1101/2023.03.18.533261 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Recurring EPHB1 mutations in human cancers alter receptor signalling and compartmentalisation of colorectal cancer cells ]]> https://biorxiv.org/content/10.1101/2023.03.18.533270v1?rss=1 Kundu, S. Nunes, L. Adler, J. Mathot, L. Stoimenov, I. Sjoblom, T. 2023-03-22 doi:10.1101/2023.03.18.533270 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Single-cell multiomic analysis reveals the involvement of Type I interferon-responsive CD8+ T cells in amyloid beta-associated memory loss ]]> https://biorxiv.org/content/10.1101/2023.03.18.533293v1?rss=1 Fernando, N. Gopalakrishnan, J. Behensky, A. Reich, L. Liu, C. Bass, V. Bono, M. Montgomery, W. De Pace, R. Mattapallil, M. Nagarajan, V. Brooks, S. Maric, D. Caspi, R. McGavern, D. Shih, H.-Y. 2023-03-22 doi:10.1101/2023.03.18.533293 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Role of GD2 and its biosynthetic enzyme GD3 synthase in prostate cancer tumorigenesis ]]> https://biorxiv.org/content/10.1101/2023.03.18.533299v1?rss=1 Bhat, A. M. Mohapatra, B. C. Luan, H. Mushtaq, I. Chakraborty, S. Dutta, S. Stock, M. D. Meza, J. L. Lin, M.-F. Cook, L. M. Corey, E. Morrissey, C. Coulter, D. W. Rowley, J. Datta, K. Band, V. Band, H. 2023-03-22 doi:10.1101/2023.03.18.533299 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Kinetic stabilization of translation-repression condensates by a neuron-specific microexon ]]> https://biorxiv.org/content/10.1101/2023.03.19.532587v1?rss=1 Garcia-Cabau, C. Bartomeu, A. Balaceanu, A. Tesei, G. Duran-Arque, B. Fernandez-Alfara, M. Martin, J. De Pace, C. Ruiz-Perez, L. Garcia, J. Battaglia, G. Lindorff-Larsen, K. Mendez, R. Salvatella, X. 2023-03-22 doi:10.1101/2023.03.19.532587 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ High performance Legionella pneumophila source attribution using genomics-based machine learning classification ]]> https://biorxiv.org/content/10.1101/2023.03.19.532693v1?rss=1 Buultjens, A. H. Vandelannoote, K. Mercoulia, K. H. Ballard, S. A. Sloggett, C. Howden, B. Seeman, T. Stinear, T. P. 2023-03-22 doi:10.1101/2023.03.19.532693 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Exploiting cryo-EM structures of actomyosin-5a to reveal the physical properties of its lever ]]> https://biorxiv.org/content/10.1101/2023.03.19.533260v1?rss=1 Gravett, M. S. C. Klebl, D. P. Harlen, O. G. Read, D. J. Harris, S. A. Muench, S. P. Peckham, M. 2023-03-22 doi:10.1101/2023.03.19.533260 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ FIREBALL: A tool to fit protein phase diagrams based on mean-field theories for polymer solutions ]]> https://biorxiv.org/content/10.1101/2023.03.19.533322v1?rss=1 Farag, M. Holehouse, A. S. Zeng, X. Pappu, R. V. 2023-03-22 doi:10.1101/2023.03.19.533322 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Structural and thermodynamic consequences of base pairs containing pseudouridine and N1-methylpseudouridine in RNA duplexes ]]> https://biorxiv.org/content/10.1101/2023.03.19.533340v1?rss=1 Dutta, N. Deb, I. Sarzynska, J. Lahiri, A. 2023-03-22 doi:10.1101/2023.03.19.533340 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Lysine-Cysteine-Lysine (KCK) tag changes ParB action in vitro but not in vivo. ]]> https://biorxiv.org/content/10.1101/2023.03.19.533373v1?rss=1 Molina, M. Way, L. E. Ren, Z. Liao, Q. Wang, X. Kim, H. 2023-03-22 doi:10.1101/2023.03.19.533373 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Structural basis for functional properties of cytochrome c oxidase ]]> https://biorxiv.org/content/10.1101/2023.03.20.530986v1?rss=1 Ishigami, I. Sierra, R. G. Su, Z. Peck, A. Wang, C. Poitevin, F. Lisova, S. Hayes, B. Moss, F. R. Boutet, S. Sublett, R. E. Yoon, C. H. Yeh, S.-R. Rousseau, D. L. 2023-03-22 doi:10.1101/2023.03.20.530986 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Characterisation of the bovine C-type lectin receptor Mincle and potential evidence for an endogenous ligand ]]> https://biorxiv.org/content/10.1101/2023.03.20.533273v1?rss=1 Holder, A. Kolakowski, J. F. Rosentreter, C. J. Knuepfer, E. Jegouzo, S. Rosenwasser, O. Harris, H. Baumgaertel, L. H. Gibson, A. J. Werling, D. 2023-03-22 doi:10.1101/2023.03.20.533273 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Semi-rational evolution of a recombinant DNA polymerase for modified nucleotide incorporation efficiency ]]> https://biorxiv.org/content/10.1101/2023.03.20.533374v1?rss=1 ZHAI, L. Wang, Z. Liu, F. Xu, C. Wang, J. Han, H. Xie, Q. Zhang, W. Zheng, Y. Buell, A. K. Dong, Y. 2023-03-22 doi:10.1101/2023.03.20.533374 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ GPR41/43 regulates blood pressure by improving gut epithelial barrier integrity to prevent TLR4 activation and renal inflammation ]]> https://biorxiv.org/content/10.1101/2023.03.20.533376v1?rss=1 R Muralitharan, R. Zheng, T. Dinakis, E. Xie, L. Barboro-Wahl, A. Jama, H. Nakai, M. Paterson, M. Johnson, C. Salimova, E. Bittto, N. Liaskos, M.-K. Kaye, D. M. O'Donnell, J. Mackay, C. R. Marques, F. Z. 2023-03-22 doi:10.1101/2023.03.20.533376 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Bacterial Peptidoglycan as a Food Digestive Signal in the Nematode that Facilitates Adaptation of Animals in Nature ]]> https://biorxiv.org/content/10.1101/2023.03.20.533399v1?rss=1 QI, B. Hao, F. Liu, H. 2023-03-22 doi:10.1101/2023.03.20.533399 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Activity-based tyrosine phosphatomics using F2Pmp probes ]]> https://biorxiv.org/content/10.1101/2023.03.20.533451v1?rss=1 Niinae, T. Ishihama, Y. 2023-03-22 doi:10.1101/2023.03.20.533451 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Shotgun proteomic analysis of the caterpillar Lonomia obliqua (Lepitoptera, Saturniidae) hemolymph and effects in rat hippocampal neurons culture ]]> https://biorxiv.org/content/10.1101/2023.03.20.533482v1?rss=1 Maggi, S. Pinto, A. F. Udo, M. S. B. Alencar da Silva, M. A. Garcia, R. C. T. Minetto, L. Tasso, L. Machado, P. Santos, D. S. Silva Junior, P. I. Barcellos, T. Mendonca, R. Z. Marcourakis, T. Moura, S. 2023-03-22 doi:10.1101/2023.03.20.533482 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Evaluation of the use of different cell types as a substrate pool for in vitro kinase reaction ]]> https://biorxiv.org/content/10.1101/2023.03.20.533483v1?rss=1 Niinae, T. Ishihama, Y. 2023-03-22 doi:10.1101/2023.03.20.533483 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Computational design of novel Cas9 PAM-interacting domains using evolution-based modelling and structural quality assessment ]]> https://biorxiv.org/content/10.1101/2023.03.20.533501v1?rss=1 Malbranke, C. Rostain, W. Depardieu, F. Cocco, S. Monasson, R. Bikard, D. 2023-03-22 doi:10.1101/2023.03.20.533501 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Testosterone acts through membrane protein GPRC6A to cause cardiac edema in zebrafish embryos ]]> https://biorxiv.org/content/10.1101/2023.03.20.533512v1?rss=1 Zadmajid, V. Gorelick, D. A. 2023-03-22 doi:10.1101/2023.03.20.533512 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Genetic screening identifies integrated stress response kinase HRI (EIF2AK1) as a negative regulator of PINK1 and mitophagy signalling ]]> https://biorxiv.org/content/10.1101/2023.03.20.533516v1?rss=1 Singh, P. Volpi, I. Agarwal, S. Wilhelm, L. P. Becchi, G. Macartney, T. Toth, R. Rousseau, A. Masson, G. Ganley, I. G. Muqit, M. M. K. 2023-03-22 doi:10.1101/2023.03.20.533516 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Fever like temperature impacts on Staphylococcus aureus and Pseudomonas aeruginosa interaction, physiology, and virulence both in vitro and in vivo ]]> https://biorxiv.org/content/10.1101/2023.03.21.529514v1?rss=1 Solar Venero, E. C. Galeano, M. B. Luqman, A. Ricardi, M. Serral, F. Fernandez Do Porto, D. Robaldi, S. A. Ashari, B. A. Z. Munif, T. H. Egoburo, D. E. Nemirovsky, S. Escalante, J. Nishimura, B. Ramirez, M. S. Götz, F. Tribelli, P. M. 2023-03-22 doi:10.1101/2023.03.21.529514 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Nucleolar Essential Protein 1 (Nep1): Elucidation of Enzymatic Catalysis Mechanism by Combined Molecular Dynamics Simulation and Quantum Chemical Calculations ]]> https://biorxiv.org/content/10.1101/2023.03.21.532383v1?rss=1 Jedrzejewski, M. Belza, B. Lewandowska, I. Sadlej, M. Perlinska, A. P. Augustyniak, R. Christian, T. Hou, Y.-M. Kalek, M. Sulkowska, J. I. 2023-03-22 doi:10.1101/2023.03.21.532383 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ How a highly acidic SH3 domain folds in the absence of its charged peptide target ]]> https://biorxiv.org/content/10.1101/2023.03.21.532811v1?rss=1 View larger version (21K): org.highwire.dtl.DTLVardef@185b8eeorg.highwire.dtl.DTLVardef@303c18org.highwire.dtl.DTLVardef@b98532org.highwire.dtl.DTLVardef@1d7ce68_HPS_FORMAT_FIGEXP M_FIG O_FLOATNOFigure 4.C_FLOATNO Analysis of domain backbone dynamics. A. 1H-15N heteronuclear NOE of AbpSH3 domain at 0 and 800 mM NaCl. B. Backbone 15N order parameters calculated from Modelfree. Error bars come from the fit. C. Atomic fluctuations of the AbpSH3 domain in no salt, 300 mM NaCl, 800 mM NaCl, and 800 mM KCl simulations. Average standard deviations in the atomic fluctuations (0.2 [A], 0.2 [A], 0.3 [A], and 0.1 [A] respectively) are larger than the difference between the lines. C_FIG ]]> Jaramillo- Martinez, V. Dominguez, M. J. Bell, G. M. Souness, M. E. Carhart, A. H. Cuibus, M. A. Masoumzadeh, E. Lantz, B. J. Adkins, A. J. Latham, M. P. Ball, K. A. Stollar, E. J. 2023-03-22 doi:10.1101/2023.03.21.532811 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Gut microbiota and fecal short chain fatty acids differ with adiposity and country of origin: The METS-Microbiome Study ]]> https://biorxiv.org/content/10.1101/2023.03.21.533195v1?rss=1 Ecklu-Mensah, G. Choo-Kang, C. Maseng, M. G. Donato, S. Bovet, P. Bedu-Addo, K. Plange-Rhule, J. Forrester, T. E. Lambert, E. V. Rae, D. Luke, A. Layden, B. T. O'Keefe, S. Gilbert, J. A. Dugas, L. R. 2023-03-22 doi:10.1101/2023.03.21.533195 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ MIL Cell: A tool for multi-scale simulation of yeast replication and prion transmission. ]]> https://biorxiv.org/content/10.1101/2023.03.21.533288v1?rss=1 HALL, D. 2023-03-22 doi:10.1101/2023.03.21.533288 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ The sliding motility of the bacilliform virions of Influenza A Viruses ]]> https://biorxiv.org/content/10.1101/2023.03.21.533586v1?rss=1 Stevens, L. de Buyl, S. Mognetti, B. M. 2023-03-22 doi:10.1101/2023.03.21.533586 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ ODF2 negatively regulates CP110 levels at centrioles/basal bodies to control biogenesis of primary cilia ]]> https://biorxiv.org/content/10.1101/2023.03.21.533604v1?rss=1 Hoyer-Fender, S. Otto, M. 2023-03-22 doi:10.1101/2023.03.21.533604 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Structure of Dimeric Lipoprotein Lipase Reveals a Pore for Hydrolysis of Acyl Chains ]]> https://biorxiv.org/content/10.1101/2023.03.21.533650v1?rss=1 Gunn, K. H. Neher, S. B. 2023-03-22 doi:10.1101/2023.03.21.533650 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Lactococcus G423 Ameliorates the Growth Performance of Broilers by Modulation of Gut Microbiota- Metabolites ]]> https://biorxiv.org/content/10.1101/2023.03.21.533656v1?rss=1 Wang, M. Ma, W. Wang, C. Li, D. Wang, Y. 2023-03-22 doi:10.1101/2023.03.21.533656 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ An epigenetic molluscicide ]]> https://biorxiv.org/content/10.1101/2023.03.21.533666v1?rss=1 Luviano, N. Halby, L. Jallet, C. Arimondo, P. Cosseau, C. Grunau, C. 2023-03-22 doi:10.1101/2023.03.21.533666 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ An endocytic myosin essential for plasma membrane invagination powers motility against resistance ]]> https://biorxiv.org/content/10.1101/2023.03.21.533689v1?rss=1 Pedersen, R. T. Snoberger, A. Pyrpassopoulos, S. Safer, D. Drubin, D. G. Ostap, E. M. 2023-03-22 doi:10.1101/2023.03.21.533689 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Balancing Functional Tradeoffs between Protein Stability and ACE2 Binding in the SARS-CoV-2 Omicron BA.2, BA.2.75 and XBB Lineages : Dynamics-Based Network Models Reveal Epistatic Effects Modulating Compensatory Dynamic and Energetic Changes ]]> https://biorxiv.org/content/10.1101/2023.03.21.533701v1?rss=1 Verkhivker, G. Alshahrani, M. Gupta, G. 2023-03-22 doi:10.1101/2023.03.21.533701 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ The primacy of experience in language processing: Semantic priming is driven primarily by experiential similarity ]]> https://biorxiv.org/content/10.1101/2023.03.21.533703v1?rss=1 View larger version (23K): org.highwire.dtl.DTLVardef@19548d4org.highwire.dtl.DTLVardef@1e070c1org.highwire.dtl.DTLVardef@a9605org.highwire.dtl.DTLVardef@ff2769_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Fernandino, L. Conant, L. L. 2023-03-22 doi:10.1101/2023.03.21.533703 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Sequence independent activity of a predicted long disordered segment of the human papillomavirus L2 capsid protein during virus entry ]]> https://biorxiv.org/content/10.1101/2023.03.21.533711v1?rss=1 Oh, C. Buckley, P. Choi, J. Hierro, A. DiMaio, D. 2023-03-22 doi:10.1101/2023.03.21.533711 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Structures of LIG1 active site mutants reveal the importance of DNA end rigidity for mismatch discrimination ]]> https://biorxiv.org/content/10.1101/2023.03.21.533718v1?rss=1 Gulkis, M. Tang, Q. Petrides, M. Caglayan, M. 2023-03-22 doi:10.1101/2023.03.21.533718 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ BCG administration promotes the long-term protection afforded by a single-dose intranasal adenovirus-based SARS-CoV-2 vaccine ]]> https://biorxiv.org/content/10.1101/2023.03.21.533720v1?rss=1 Perera, D. J. Domenech, P. Babuadze, G. G. Naghibosadat, M. Alvarez, F. Koger-Pease, C. Labrie, L. Stuible, M. Durocher, Y. Piccirillo, C. A. Lametti, A. Fiset, P. O. Elahi, S. M. Kobinger, G. P. Gilbert, R. Olivier, M. Kozak, R. Reed, M. B. Ndao, M. 2023-03-22 doi:10.1101/2023.03.21.533720 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ The structural basis of hyperpromiscuity in a core combinatorial network of Type II toxin-antitoxin and related phage defence systems ]]> https://biorxiv.org/content/10.1101/2023.03.22.533649v1?rss=1 Ernits, K. Saha, C. K. Brodiazhenko, T. Chouhan, B. Shenoy, A. Duque-Pedraza, J. J. Bojar, V. Nakamoto, J. A. Kurata, T. Egorov, A. Shyrokova, L. Johansson, M. J. O. Mets, T. Rustamova, A. Dzigurski, J. Tenson, T. Garcia-Pino, A. Elofsson, A. Hauryliuk, V. Atkinson, G. C. 2023-03-22 doi:10.1101/2023.03.22.533649 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Reliable Particle Sizing in Vaccine Formulations using Advanced Dynamic LightScattering ]]> https://biorxiv.org/content/10.1101/2023.03.22.533677v1?rss=1 Bretz, C. Jauslin, A. Leumann, D. Koch, M. Vaccaro, A. 2023-03-22 doi:10.1101/2023.03.22.533677 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Selective inhibitors of the Aurora A-TPX2 protein-protein interaction exhibit in vivo efficacy as targeted anti-mitotic agents ]]> https://biorxiv.org/content/10.1101/2023.03.22.533679v1?rss=1 Stockwell, S. R. Scott, D. E. Fischer, G. Guarino, E. Rooney, T. P. C. Fang, T.-S. Moschetti, T. Srinivasan, R. Alza, E. Asteian, A. Dagostin, C. Alcaide, A. Rocaboy, M. Blaszczyk, B. Higueruelo, A. Wang, X. Rossmann, M. Perrior, T. R. Blundell, T. L. Spring, D. R. McKenzie, G. Abell, C. Skidmore, J. Hyvönen, M. Venkitaraman, A. R. 2023-03-22 doi:10.1101/2023.03.22.533679 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Mitigation of chromosome loss in clinical CRISPR-Cas9-engineered T cells ]]> https://biorxiv.org/content/10.1101/2023.03.22.533709v1?rss=1 Tsuchida, C. A. Brandes, N. Bueno, R. Trinidad, M. Mazumder, T. Yu, B. Hwang, B. Chang, C. Liu, J. Sun, Y. Hopkins, C. R. Parker, K. R. Qi, Y. Satpathy, A. Stadtmauer, E. Cate, J. H. D. Eyquem, J. Fraietta, J. A. June, C. H. Chang, H. Y. Ye, C. J. Doudna, J. A. 2023-03-22 doi:10.1101/2023.03.22.533709 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ B cell-intrinsic STAT3-mediated support of latency and interferon suppression during murine gammaherpesvirus 68 infection revealed through an in vivo competition model ]]> https://biorxiv.org/content/10.1101/2023.03.22.533727v1?rss=1 Hogan, C. H. Owens, S. M. Reynoso, G. V. Kirillov, V. Meyer, T. J. Zelazowska, M. A. Liu, B. Li, X. Chikhalya, A. Dong, Q. Khairallah, C. Reich, N. C. Sheridan, B. McBride, K. M. Hearing, P. Hickman, H. D. Forrest, J. C. Krug, L. T. 2023-03-22 doi:10.1101/2023.03.22.533727 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Structure and Function of the Dot/Icm T4SS ]]> https://biorxiv.org/content/10.1101/2023.03.22.533729v1?rss=1 Dutka, P. Liu, Y. Maggi, S. Ghosal, D. Wang, J. Carter, S. D. Zhao, W. Vijayrajratnam, S. Vogel, J. P. Jensen, G. J. 2023-03-22 doi:10.1101/2023.03.22.533729 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Temporal genome-wide fitness analysis of Mycobacterium marinum during infection reveals genetic requirement for virulence and survival in amoebae and microglial cells ]]> https://biorxiv.org/content/10.1101/2023.03.22.533734v1?rss=1 Lefrancois, L. H. Nitschke, J. Panis, G. Prados, J. Butler, R. E. Mendum, T. A. Hanna, N. Stewart, G. R. Soldati, T. 2023-03-22 doi:10.1101/2023.03.22.533734 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Identification and characterization of two CRISPR-Cas systems associated with the mosquito microbiome ]]> https://biorxiv.org/content/10.1101/2023.03.22.533747v1?rss=1 hegde, S. Rauch, H. E. Hughes, G. L. Shariat, N. 2023-03-22 doi:10.1101/2023.03.22.533747 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Interspecies interactions determine growth dynamics of biopolymer degrading populations in microbial communities. ]]> https://biorxiv.org/content/10.1101/2023.03.22.533748v1?rss=1 D'souza, G. Schwartzman, J. Keegstra, J. Schreier, J. E. Daniels, M. Cordero, O. Stocker, R. Ackermann, M. 2023-03-22 doi:10.1101/2023.03.22.533748 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Lysosome damage triggers direct ATG8 conjugation and ATG2 engagement via CASM ]]> https://biorxiv.org/content/10.1101/2023.03.22.533754v1?rss=1 Cross, J. Durgan, J. McEwan, D. G. Florey, O. 2023-03-22 doi:10.1101/2023.03.22.533754 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Multicellular PD Control in Microbial Consortia ]]> https://biorxiv.org/content/10.1101/2023.03.22.533755v1?rss=1 Martinelli, V. Salzano, D. Fiore, D. di Bernardo, M. 2023-03-22 doi:10.1101/2023.03.22.533755 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Spatiotemporal analysis of SARS-CoV-2 infection reveals an expansive wave of monocyte-derived macrophages associated with vascular damage and virus clearance in hamster lungs ]]> https://biorxiv.org/content/10.1101/2023.03.22.533759v1?rss=1 Bagato, O. Balkema-Buschmann, A. Todt, D. Weber, S. Goemer, A. Qu, B. Miskey, C. Mettenleiter, T. C. Finke, S. Brown, R. J. P. Breithaupt, A. Ushakov, D. S. 2023-03-22 doi:10.1101/2023.03.22.533759 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ The C. elegans proteome response to two protective Pseudomonas symbionts ]]> https://biorxiv.org/content/10.1101/2023.03.22.533766v1?rss=1 Pees, B. Peters, L. Treitz, C. Hamerich, I. K. Kissoyan, K. A. Tholey, A. Dierking, K. 2023-03-22 doi:10.1101/2023.03.22.533766 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Homocysteine Metabolites Inhibit Autophagy and Elevate Amyloid Beta by Impairing Phf8/H4K20me1-dependent Epigenetic Regulation of mTOR in Cystathionine Beta-Synthase-Deficient Mice ]]> https://biorxiv.org/content/10.1101/2023.03.22.533769v1?rss=1 H4K20me1->mTOR->autophagy pathway thereby increasing A{beta} accumulation. ]]> Witucki, L. Jakubowski, H. 2023-03-22 doi:10.1101/2023.03.22.533769 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Thermogenetic control of Ca2+ levels in cells and tissues ]]> https://biorxiv.org/content/10.1101/2023.03.22.533774v1?rss=1 Ermakova, Y. G. Waadt, R. Ozturk, M. S. Roshchin, M. Lanin, A. A. Chebotarev, A. Pochechuev, M. Pak, V. Kelmanson, I. Smolyarovasmol, D. Keutler, K. Matyushenko, A. M. Tischer, C. V. Balaban, P. M. Nikitin, E. S. Schumacher, K. Zheltikov, A. Prevedel, R. Schultz, C. Belousov, V. V. 2023-03-22 doi:10.1101/2023.03.22.533774 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Protective role of protease-activated receptor-2 in anaphylaxis model mice ]]> https://biorxiv.org/content/10.1101/2023.03.22.533779v1?rss=1 Nakazawa, M. Tochinai, R. Fujii, W. Yonezawa, T. Momoi, Y. Maeda, S. 2023-03-22 doi:10.1101/2023.03.22.533779 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Temporal progression of anaerobic fungal communities in dairy calves from birth to maturity ]]> https://biorxiv.org/content/10.1101/2023.03.22.533786v1?rss=1 Jones, A. L. Clayburn, J. Pribil, E. Foote, A. Montgomery, D. Elshahed, M. Youssef, N. H. 2023-03-22 doi:10.1101/2023.03.22.533786 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ A multiplex PCR assay for the detection of Cryptosporidium species and simultaneous differentiation of Cryptosporidium hominis, Cryptosporidium parvum in clinical stool samples ]]> https://biorxiv.org/content/10.1101/2023.03.22.533796v1?rss=1 Katiyar, M. Padukone, S. Gulati, R. Singh, R. 2023-03-22 doi:10.1101/2023.03.22.533796 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ EGGNet, a generalizable geometric deep learning framework for protein complex pose scoring ]]> https://biorxiv.org/content/10.1101/2023.03.22.533800v1?rss=1 Wang, Z. Brand, R. Adolf-Bryfogle, J. Grewal, J. Qi, Y. Combs, S. A. Golovach, N. Alford, R. Rangwala, H. Clark, P. M. 2023-03-22 doi:10.1101/2023.03.22.533800 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Mechanism of tension propagation in cell membranes ]]> https://biorxiv.org/content/10.1101/2023.03.22.533804v1?rss=1 Barnoy, A. Tsaturyan, A. K. Kozlov, M. M. 2023-03-22 doi:10.1101/2023.03.22.533804 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Evolving antibody evasion and receptor affinity of the Omicron BA.2.75 sublineage of SARS-CoV-2 ]]> https://biorxiv.org/content/10.1101/2023.03.22.533805v1?rss=1 Wang, Q. Li, Z. Guo, Y. Mellis, I. A. Iketani, S. Liu, M. Yu, J. Valdez, R. Lauring, A. S. Sheng, Z. Gordon, A. Liu, L. Ho, D. D. 2023-03-22 doi:10.1101/2023.03.22.533805 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Assessing vaccine-mediated protection in an ultra-low dose Mycobacterium tuberculosis murine model ]]> https://biorxiv.org/content/10.1101/2023.03.22.533820v1?rss=1 Plumlee, C. R. Barrett, H. W. Shao, D. E. Lien, K. A. Cross, L. M. Cohen, S. B. Edlefsen, P. T. Urdahl, K. B. 2023-03-22 doi:10.1101/2023.03.22.533820 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Emerging Antifungal Resistance in Falco Species: A Novel Model for Human Medicine ]]> https://biorxiv.org/content/10.1101/2023.03.22.533837v1?rss=1 DAS, S. CHRISTU, S. D. SILVANOSE, C. BINOY, A. AZMANIS, P. DI SOMMA, A. GLADSTON, J. V. 2023-03-22 doi:10.1101/2023.03.22.533837 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Mammalian cell characterisation by non-invasive plate reader assay ]]> https://biorxiv.org/content/10.1101/2023.03.22.533848v1?rss=1 Grob, A. Bena, C. E. Di Blasi, R. Pessina, D. Sood, M. Yunyue, Z. Bosia, C. Isalan, M. Ceroni, F. 2023-03-22 doi:10.1101/2023.03.22.533848 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Identification of a Novel PARP14 Site Motif and Glycohydrolase Specificity Using TLC-MALDI-TOF ]]> https://biorxiv.org/content/10.1101/2023.03.22.533863v1?rss=1 Javed, Z. Nguyen, H. H. Harker, K. Mohr, C. M. Vano, P. Wallace, S. R. Silvers, C. Sim, C. Turumella, S. Flinn, A. Carter-O'Connell, I. 2023-03-22 doi:10.1101/2023.03.22.533863 Cold Spring Harbor Laboratory Press 2023-03-22 <![CDATA[ Bacillus Calmette-Guerin infection in NADPH oxidase deficiency: defective mycobacterial sequestration and granuloma formation ]]> https://biorxiv.org/content/10.1101/005835v1?rss=1 Christine Deffert Michela G. Schäppi Jean-Claude Pache Julien Cachat Dominique Vesin Ruth Bisig Xiaojuan Ma Mulone Tiina Kelkka Rikard Holmdahl Irene Garcia Maria L. Olleros Karl-Heinz Krause 2014-06-03 doi:10.1101/005835 Cold Spring Harbor Laboratory Press 2014-06-03 <![CDATA[ Assessing allele specific expression across multiple tissues from RNA-seq read data ]]> https://biorxiv.org/content/10.1101/007211v1?rss=1 Matti Pirinen Tuuli Lappalainen Noah A Zaitlen GTEx Consortium Emmanouil T Dermitzakis Peter Donnelly Mark I McCarthy Manuel A Rivas 2014-07-17 doi:10.1101/007211 Cold Spring Harbor Laboratory Press 2014-07-17 <![CDATA[ Long non-coding RNA discovery in Anopheles gambiae using deep RNA sequencing ]]> https://biorxiv.org/content/10.1101/007484v1?rss=1 Adam M Jenkins Robert M Waterhouse Alan S Kopin Marc A.T. Muskavitch 2014-07-26 doi:10.1101/007484 Cold Spring Harbor Laboratory Press 2014-07-26 <![CDATA[ Transcriptome Sequencing Reveals Widespread Gene-Gene and Gene-Environment Interactions ]]> https://biorxiv.org/content/10.1101/010546v1?rss=1 Alfonso Buil Andrew A Brown Tuuli Lappalainen Ana Viñuela Matthew N Davies Houfeng F Zheng Brent J Richards Daniel Glass Kerrin S Small Richard Durbin Timothy D Spector Emmanouil T Dermitzakis 2014-10-19 doi:10.1101/010546 Cold Spring Harbor Laboratory Press 2014-10-19 <![CDATA[ Alternative splicing QTLs in European and African populations using Altrans, a novel method for splice junction quantification ]]> https://biorxiv.org/content/10.1101/014126v1?rss=1 Halit Ongen Emmanouil T Dermitzakis 2015-01-22 doi:10.1101/014126 Cold Spring Harbor Laboratory Press 2015-01-22 <![CDATA[ Fast and efficient QTL mapper for thousands of molecular phenotypes ]]> https://biorxiv.org/content/10.1101/022301v1?rss=1 Halit Ongen Alfonso Buil Andrew Brown Emmanouil Dermitzakis Olivier Delaneau 2015-08-07 doi:10.1101/022301 Cold Spring Harbor Laboratory Press 2015-08-07 <![CDATA[ A spatio-temporal model for spontaneous thrombus formation in cerebral aneurysms ]]> https://biorxiv.org/content/10.1101/023226v1?rss=1 Orestis Malaspinas Alexis Turjman Daniel Ribeiro de Sousa Guillermo Garcia-Cardena Martine Raes Phuc-Thien Thomas Nguyen Yue Zhang Guy Courbebaisse Christophe Lelubre Karim Zouaoui Boudjeltia Bastien Chopard 2015-07-27 doi:10.1101/023226 Cold Spring Harbor Laboratory Press 2015-07-27 <![CDATA[ Early farmers from across Europe directly descended from Neolithic Aegeans ]]> https://biorxiv.org/content/10.1101/032763v1?rss=1 Zuzana Hofmanová Susanne Kreutzer Garrett Hellenthal Christian Sell Yoan Diekmann David Díez del Molino Lucy van Dorp Saioa López Athanasios Kousathanas Vivian Link Karola Kirsanow Lara M Cassidy Rui Martiniano Melanie Strobel Amelie Scheu Kostas Kotsakis Paul Halstead Sevi Triantaphyllou Nina Kyparissi-Apostolika Dushanka-Christina Urem-Kotsou Christina Ziota Fotini Adaktylou Shyamalika Gopalan Dean M Bobo Laura Winkelbach Jens Blöcher Martina Unterländer Christoph Leuenberger Çiler Çilingiroğlu Barbara Horejs Fokke Gerritsen Stephen Shennan Daniel G Bradley Mathias Currat Krishna Veeramah Da 2015-11-25 doi:10.1101/032763 Cold Spring Harbor Laboratory Press 2015-11-25 <![CDATA[ solarius: an R interface to SOLAR for variance component analysis in pedigrees ]]> https://biorxiv.org/content/10.1101/035378v1?rss=1 Andrey Ziyatdinov Helena Brunel Angel Martinez-Perez Alfonso Buil Alexandre Perera Jose Manuel Soria 2015-12-25 doi:10.1101/035378 Cold Spring Harbor Laboratory Press 2015-12-25 <![CDATA[ Human mismatch repair system corrects errors produced during lagging strand replication more effectively ]]> https://biorxiv.org/content/10.1101/045278v1?rss=1 Maria Andrianova Georgii A Bazykin Sergey Nikolaev Vladimir Seplyarskiy 2016-03-23 doi:10.1101/045278 Cold Spring Harbor Laboratory Press 2016-03-23 <![CDATA[ Mixing of Porpoise Ecotypes in South Western UK Waters Revealed by Genetic Profiling ]]> https://biorxiv.org/content/10.1101/045807v1?rss=1 Michael C Fontaine Oliver Thatcher Nicolas Ray Sylvain Piry Andrew Brownlow Nicholas J. Davison Paul Jepson Rob Deaville Simon J Goodman 2016-03-27 doi:10.1101/045807 Cold Spring Harbor Laboratory Press 2016-03-27 <![CDATA[ Evolutionary dynamics of abundant stop codon readthrough in Anopheles and Drosophila ]]> https://biorxiv.org/content/10.1101/051557v1?rss=1 Irwin Jungreis Clara S Chan Robert M Waterhouse Gabriel Fields Michael F Lin Manolis Kellis 2016-05-03 doi:10.1101/051557 Cold Spring Harbor Laboratory Press 2016-05-03 <![CDATA[ Effect of population structure and migration when investigating genetic continuity using ancient DNA ]]> https://biorxiv.org/content/10.1101/052548v1?rss=1 Nuno M Silva Susanne Kreutzer Christina Papageorgopoulou Mathias Currat 2016-05-10 doi:10.1101/052548 Cold Spring Harbor Laboratory Press 2016-05-10 <![CDATA[ Quantifying the degree of sharing of genetic and non-genetic causes of gene expression variability across four tissues. ]]> https://biorxiv.org/content/10.1101/053355v1?rss=1 90% for 35% of the genes, indicating for these genes a largely tissue-shared component of cis regulation. However, variance components show that cis genetic signals explain only a small fraction of the variation in expression, with from 67-87% of the variance explained by environmental factors, and 53% of the genetic effects occurring in trans. We observe a trans genetic correlation of 0 for all genes except a few which show correlation between fat and skin expression. The environmental effects are also observed to be entirely tissue specific, despite related tissues largely sharing exposures. These results demonstrate that patterns of gene expression are largely tissue specific, strongly supporting the need to study higher order regulatory interactions in the appropriate tissue context with large samples sizes and diversity of environmental contexts. ]]> Alfonso Buil Ana Viñuela Andrew Brown Matthew Davies Ismael Padioleau Deborah Bielser Luciana Romano Daniel Glass Paola Di Meglio Kerrin Small Timothy Spector Emmanouil T Dermitzakis 2016-05-13 doi:10.1101/053355 Cold Spring Harbor Laboratory Press 2016-05-13 <![CDATA[ DNA sequence properties that predict susceptibility to epiallelic switching ]]> https://biorxiv.org/content/10.1101/057794v1?rss=1 Marco Catoni Jayne Griffiths Claude Becker Nicolae Radu Zabet Carlos Bayon Melanie Dapp Michal Lieberman-Lazarovich Detlef Weigel Jerzy Paszkowski 2016-06-08 doi:10.1101/057794 Cold Spring Harbor Laboratory Press 2016-06-08 <![CDATA[ Age-dependent changes in mean and variance of gene expression across tissues in a twin cohort ]]> https://biorxiv.org/content/10.1101/063883v1?rss=1 Ana Vinuela Andrew Anand Brown Alfonso Buil Pei-Chien Tsai Matthew N Davies Jordana Tzenova Bell Emmanouil Dermitzakis Timothy Spector Kerrin Small 2016-07-14 doi:10.1101/063883 Cold Spring Harbor Laboratory Press 2016-07-14 <![CDATA[ Cohort Specific Effects of Cereal-bar Supplementation in Overweight Patients With or Without Type 2 Diabetes Mellitus ]]> https://biorxiv.org/content/10.1101/066704v1?rss=1 Chris Lauber Chieh Jason Chou Anirikh Chakrabarti Jay Siddharth Anne Chalut-Carpentier Zoltan Pataky Alain Golay Scott Parkinson 2016-07-29 doi:10.1101/066704 Cold Spring Harbor Laboratory Press 2016-07-29 <![CDATA[ A complete tool set for molecular QTL discovery and analysis ]]> https://biorxiv.org/content/10.1101/068635v1?rss=1 Olivier Delaneau Halit Ongen Andrew Anand Brown Alexandre Fort Nikolaos Panousis Emmanouil Dermitzakis 2016-08-10 doi:10.1101/068635 Cold Spring Harbor Laboratory Press 2016-08-10 <![CDATA[ Physical model of the sequence-to-function map of proteins ]]> https://biorxiv.org/content/10.1101/069039v1?rss=1 Tsvi Tlusty Albert Libchaber Jean-Pierre Eckmann 2016-08-12 doi:10.1101/069039 Cold Spring Harbor Laboratory Press 2016-08-12 <![CDATA[ Evidence that low socioeconomic position accentuates genetic susceptibility to obesity ]]> https://biorxiv.org/content/10.1101/074054v1?rss=1 Jess Tyrrell Andrew R Wood Ryan M Ames Hanieh Yaghootkar Robin Beaumont Samuel E Jones Marcus A Tuke Katherine S Ruth Rachel M Freathy George Davey-Smith Stephane Joost Idris Guessous Anna Murray David P Strachan Zoltan Kutalik Michael N Weedon Timothy M Frayling 2016-09-13 doi:10.1101/074054 Cold Spring Harbor Laboratory Press 2016-09-13 <![CDATA[ Distant regulatory effects of genetic variation in multiple human tissues ]]> https://biorxiv.org/content/10.1101/074419v1?rss=1 Brian Jo Yuan He Benjamin J Strober Princy Parsana Francois Aguet Andrew A Brown Stephane E Castel Eric R Gamazon Ariel Gewirtz Genna Gliner Buhm Han Amy Z He Eun Yong Kang Ian C McDowell Xiao Li Pejman Mohammadi Christine B Peterson Gerald Quon Ashis Saha Ayellet V Segre Jae Hoon Sul Timothy J Sullivan Kristin G Ardlie Christopher D Brown Donald F Conrad Nancy J Cox Emmanouil T Dermitzakis Eleazar Eskin Manolis Kellis Tuuli Lappalainen Chiara Sabatti GTEx Consortium Barbara E Engelhardt Alexis Battle 2016-09-09 doi:10.1101/074419 Cold Spring Harbor Laboratory Press 2016-09-09 <![CDATA[ Local genetic effects on gene expression across 44 human tissues ]]> https://biorxiv.org/content/10.1101/074450v1?rss=1 Francois Aguet Andrew A Brown Stephane Castel Joe R Davis Pejman Mohammadi Ayellet V Segre Zachary Zappala Nathan S Abell Laure Fresard Eric R Gamazon Ellen Gelfand Machael J Gloudemans Yuan He Farhad Hormozdiari Xiao Li Xin Li Boxiang Liu Diego Garrido-Martin Halit Ongen John J Palowitch YoSon Park Christine B Peterson Gerald Quon Stephan Ripke Andrey A Shabalin Tyler C Shimko Benjamin J Strober Timothy J Sullivan Nicole A Teran Emily K Tsang Hailei Zhang Yi-Hui Zhou Alexis Battle Carlos D Bustamonte Nancy J Cox Barbara E Engelhardt Eleazar Eskin Gad Getz Manolis Kellis Gen Li Daniel G MacArt 2016-09-09 doi:10.1101/074450 Cold Spring Harbor Laboratory Press 2016-09-09 <![CDATA[ Estimating the causal tissues for complex traits and diseases ]]> https://biorxiv.org/content/10.1101/074682v1?rss=1 Halit Ongen Andrew A Brown Olivier Delaneau Nikolaos Panousis Alexandra C Nica GTEx Consortium Emmanouil T Dermitzakis 2016-09-11 doi:10.1101/074682 Cold Spring Harbor Laboratory Press 2016-09-11 <![CDATA[ ROLE OF TOLERANCE TO RESOURCE DEMAND -- SUPPLY MISMATCH IN A MODEL OF ANNUAL PLANTS ]]> https://biorxiv.org/content/10.1101/075804v1?rss=1 Michel Droz Andrzej Pekalski 2016-09-19 doi:10.1101/075804 Cold Spring Harbor Laboratory Press 2016-09-19 <![CDATA[ COMPARISON OF TWO DESCRIPTIONS OF HETEROGENEITY USED IN MODELLING PLANTS DYNAMICS ]]> https://biorxiv.org/content/10.1101/075812v1?rss=1 Michel Droz Andrzej Pękalski 2016-09-19 doi:10.1101/075812 Cold Spring Harbor Laboratory Press 2016-09-19 <![CDATA[ Mapping eQTLs With RNA-Seq Reveals Novel SLE Susceptibility Genes, Non-Coding RNAs, and Alternative-Splicing Events That Are Concealed Using Microarrays ]]> https://biorxiv.org/content/10.1101/076026v1?rss=1 Christopher A Odhams Andrea Cortini Lingyan Chen Amy L Roberts Ana Vinuela Alfonso Buil Kerrin S Small Emmanouil T Dermitzakis David L Morris Timothy J Vyse Deborah S Cunninghame-Graham 2016-09-19 doi:10.1101/076026 Cold Spring Harbor Laboratory Press 2016-09-19 <![CDATA[ Transcriptional regulatory logic of the diurnal cycle in the mouse liver ]]> https://biorxiv.org/content/10.1101/077818v1?rss=1 Jonathan Aryeh Sobel Irina Krier Teemu Andersin Sunil Raghav Donatella Canella Federica Gilardi Alexandra Styliani Kalantzi Guillaume Rey Benjamin Weger Frederic Gachon Matteo Dal Peraro Nouria Hernandez Ueli Schibler Bart Deplancke Felix Naef CycliX consortium 2016-09-27 doi:10.1101/077818 Cold Spring Harbor Laboratory Press 2016-09-27 <![CDATA[ Quantifying the regulatory effect size of cis-acting genetic variation using allelic fold change ]]> https://biorxiv.org/content/10.1101/078717v1?rss=1 Pejman Mohammadi Stephane E Castel Andrew A Brown Tuuli Lappalainen 2016-09-30 doi:10.1101/078717 Cold Spring Harbor Laboratory Press 2016-09-30 <![CDATA[ Rapid evolution of female-biased genes among four species of Anopheles malaria mosquitoes ]]> https://biorxiv.org/content/10.1101/081620v1?rss=1 Papa, F. Windbichler, N. Waterhouse, R. M. Cagnetti, A. D'Amato, R. Presampieri, T. Lawniczak, M. K. N. Nolan, T. Papathanos, P. A. A. 2016-10-17 doi:10.1101/081620 Cold Spring Harbor Laboratory Press 2016-10-17 <![CDATA[ Predicting causal variants affecting expression using whole genome sequence and RNA-seq from multiple human tissues. ]]> https://biorxiv.org/content/10.1101/088872v1?rss=1 Brown, A. A. Vinuela, A. Delaneau, O. Spector, T. Small, K. Dermitzakis, E. 2016-11-21 doi:10.1101/088872 Cold Spring Harbor Laboratory Press 2016-11-21 <![CDATA[ A Novel DNA-binding Protein Coordinates Asymmetric Chromosome Replication and Chromosome Partitioning ]]> https://biorxiv.org/content/10.1101/091496v1?rss=1 Taylor, J. Panis, G. Viollier, P. Marczynski, G. 2016-12-04 doi:10.1101/091496 Cold Spring Harbor Laboratory Press 2016-12-04 <![CDATA[ Cell Cycle Constraints and Environmental Control of Local DNA Hypomethylation in Alpha-Proteobacteria ]]> https://biorxiv.org/content/10.1101/091785v1?rss=1 Ardissone, S. Redder, P. Russo, G. Frandi, A. Fumeaux, C. Patrignani, A. Schlapbach, R. Falquet, L. Viollier, P. H. 2016-12-06 doi:10.1101/091785 Cold Spring Harbor Laboratory Press 2016-12-06 <![CDATA[ Pharmacogenetics of antidepressant response: a polygenic approach ]]> https://biorxiv.org/content/10.1101/093799v1?rss=1 García-González, J Tansey, K Hauser, J Henigsberg, N Maier, W Mors, O Placentino, A Rietschel, M Souery, D Žagar, T Czerski, P Jerman, B Buttenschøn, H Schulze, T Zobel, A Farmer, A Aitchison, K Craig, I McGuffin, P Giupponi, M Perroud, N Bondolfi, G Evans, D O'Donovan, M Peters, T Wendland, J Lewis, G Kapur, S Perlis, R Arolt, V Domschke, K Breen, G Curtis, C Sang-Hyuk, L Kan, C Newhouse, S Patel, H Baune, B Uher, R Lewis, C Fabbri, C 2016-12-14 doi:10.1101/093799 Cold Spring Harbor Laboratory Press 2016-12-14 <![CDATA[ Human pancreatic β cell lncRNAs control cell-specific regulatory networks ]]> https://biorxiv.org/content/10.1101/096230v1?rss=1 Akerman, I. Tu, Z. Beucher, A. Rolando, D. Sauty-Colace, C. Benazra, M. Nakic, N. Yang, J. Wang, H. Pasquali, L. Moran, I. Garcia-Hurtado, J. Castro, N. Gonzalez-Franco, R. Stewart, A. F. Bonner, C. Piemonti, L. Berney, T. Groop, L. Kerr-Conte, J. Pattou, F. Argmann, C. Schadt, E. Ravassard, P. Ferrer, J. 2016-12-23 doi:10.1101/096230 Cold Spring Harbor Laboratory Press 2016-12-23 <![CDATA[ Inferring decoding strategies for multiple correlated neural populations ]]> https://biorxiv.org/content/10.1101/108019v1?rss=1 Lakshminarasimhan, K. Pouget, A. DeAngelis, G. Angelaki, D. Pitkow, X. 2017-02-13 doi:10.1101/108019 Cold Spring Harbor Laboratory Press 2017-02-13 <![CDATA[ New insights on the pharmacogenomics of antidepressant response from the GENDEP and STAR*D studies: rare variant analysis and high-density imputation ]]> https://biorxiv.org/content/10.1101/109827v1?rss=1 Fabbri, C. Tansey, K. Perlis, R. Hauser, J. Henigsberg, N. Maier, W. Mors, O. Placentino, A. Rietschel, M. Souery, D. Breen, G. Curtis, C. Sang-Hyuk, L. Newhouse, S. Patel, H. Guipponi, M. Perroud, N. Bondolfi, G. O'Donovan, M. Lewis, G. Biernacka, J. Weinshilboum, R. Farmer, A. Aitchison, K. Craig, I. McGuffin, P. Uher, R. Lewis, C. 2017-02-20 doi:10.1101/109827 Cold Spring Harbor Laboratory Press 2017-02-20 <![CDATA[ MRIQC: Predicting Quality in Manual MRI Assessment Protocols Using No-Reference Image Quality Measures ]]> https://biorxiv.org/content/10.1101/111294v1?rss=1 Esteban, O. Birman, D. Schaer, M. Koyejo, O. O. Poldrack, R. A. Gorgolewski, K. J. 2017-02-24 doi:10.1101/111294 Cold Spring Harbor Laboratory Press 2017-02-24 <![CDATA[ First landscape of binding to chromosomes for a domesticated mariner transposase in the human genome: diversity of genomic targets of SETMAR isoforms in two colorectal cell lines ]]> https://biorxiv.org/content/10.1101/115030v1?rss=1 Antoine-Lorquin, A. Arnoaty, A. Asgari, S. Batailler, M. Beauclair, L. Bire, S. Buisine, N. Coustham, V. Girault, A. Guyetant, S. Lecomte, T. Piegu, B. Pitard, B. Stevant, I. Belleannee, C. Bigot, Y. 2017-03-09 doi:10.1101/115030 Cold Spring Harbor Laboratory Press 2017-03-09 <![CDATA[ LARGE-SCALE GENOMIC REORGANIZATIONS OF TOPOLOGICAL DOMAINS (TADs) AT THE HoxD LOCUS ]]> https://biorxiv.org/content/10.1101/116152v1?rss=1 Fabre, P. J. Leleu, M. Mormann, B. H. Delisle, L. Noordermeer, D. Beccari, L. Duboule, D. 2017-03-12 doi:10.1101/116152 Cold Spring Harbor Laboratory Press 2017-03-12 <![CDATA[ Periaqueductal Efferents To Dopamine And GABA Neurons Of The VTA ]]> https://biorxiv.org/content/10.1101/117416v1?rss=1 Ntamati, N. R. Creed, M. Luscher, C. 2017-03-16 doi:10.1101/117416 Cold Spring Harbor Laboratory Press 2017-03-16 <![CDATA[ Context-Dependent Attractor Dynamics in Visual Cortex ]]> https://biorxiv.org/content/10.1101/120725v1?rss=1 Tajima, S. Koida, K. Tajima, C. I. Suzuki, H. Aihara, K. Komatsu, H. 2017-03-26 doi:10.1101/120725 Cold Spring Harbor Laboratory Press 2017-03-26 <![CDATA[ Distributed Affective Space Represents Multiple Emotion Categories Across The Brain ]]> https://biorxiv.org/content/10.1101/123521v1?rss=1 Saarimaki, H. Ejtehadian, L. F. Glerean, E. Jaaskelainen, I. P. Vuilleumier, P. Sams, M. Nummenmaa, L. 2017-04-05 doi:10.1101/123521 Cold Spring Harbor Laboratory Press 2017-04-05 <![CDATA[ Sub-minute phosphoregulation of cell-cycle systems during Plasmodium gamete formation revealed by a high-resolution time course ]]> https://biorxiv.org/content/10.1101/126276v1?rss=1 Invergo, B. Brochet, M. Yu, L. Choudhary, J. Beltrao, P. Billker, O. 2017-04-10 doi:10.1101/126276 Cold Spring Harbor Laboratory Press 2017-04-10 <![CDATA[ Development of a Self-Report Measure of Reward Sensitivity: A Test in Current and Former Smokers ]]> https://biorxiv.org/content/10.1101/128793v1?rss=1 Hughes, J. R. Callas, P. W. Priest, J. S. Etter, J.-F. Budney, A. J. Sigmon, S. C. 2017-04-20 doi:10.1101/128793 Cold Spring Harbor Laboratory Press 2017-04-20 <![CDATA[ Distance Is Not Everything In Imaging Genomics Of Functional Networks: Reply To A Commentary On Correlated Gene Expression Supports Synchronous Activity In Brain Networks ]]> https://biorxiv.org/content/10.1101/132746v1?rss=1 Richiardi, J. Altmann, A. Greicius, M. 2017-05-01 doi:10.1101/132746 Cold Spring Harbor Laboratory Press 2017-05-01 <![CDATA[ Focal Versus Distributed Temporal Cortex Activity For Speech Sound Category Assignment ]]> https://biorxiv.org/content/10.1101/133272v1?rss=1 Bouton, S. Chambon, V. Tyrand, R. Guggisberg, A. G. Seeck, M. Karkar, S. van de Ville, D. Giraud, A.-L. 2017-05-02 doi:10.1101/133272 Cold Spring Harbor Laboratory Press 2017-05-02 <![CDATA[ The Population Genomics Of Archaeological Transition In West Iberia ]]> https://biorxiv.org/content/10.1101/134254v1?rss=1 Martiniano, R. Cassidy, L. M. O'Maolduin, R. McLaughlin, R. Silva, N. M. Manco, L. Fidalgo, D. Pereira, T. Coelho, M. J. Serra, M. Burger, J. Parreira, R. Moran, E. Valera, A. Porfirio, E. Boaventura, R. Silva, A. M. Bradley, D. G. 2017-05-10 doi:10.1101/134254 Cold Spring Harbor Laboratory Press 2017-05-10 <![CDATA[ Improving Leukemic CD34+/CD38- Blasts Characterization With Single-Cell Transcriptome Sequencing ]]> https://biorxiv.org/content/10.1101/141754v1?rss=1 Sartori, A. Cheng, P. Falconnet, E. Ribaux, P. Aubry-Lachainaye, J.-P. Levesque, M. P. Antonarakis, S. E. Matthes, T. Borel, C. 2017-05-31 doi:10.1101/141754 Cold Spring Harbor Laboratory Press 2017-05-31 <![CDATA[ Restoring wild type-like network dynamics and behaviour during adulthood in a mouse model of schizophrenia ]]> https://biorxiv.org/content/10.1101/151795v1?rss=1 Marissal, T. Salazar, R. F. Bertollini, C. Mutel, S. De Roo, M. Rodriguez, I. Muller, D. Carleton, A. 2017-06-19 doi:10.1101/151795 Cold Spring Harbor Laboratory Press 2017-06-19 <![CDATA[ Hydra, a model system for deciphering the mechanisms of aging and resistance to aging ]]> https://biorxiv.org/content/10.1101/155804v1?rss=1 Schenkelaars, Q. Tomczyk, S. Wenger, Y. Ekundayo, K. Girard, V. Buzgariu, W. Austad, S. Galliot, B. 2017-06-26 doi:10.1101/155804 Cold Spring Harbor Laboratory Press 2017-06-26 <![CDATA[ Tension-dependent stretching and folding of ZO-1 controls the localization of its interactors ]]> https://biorxiv.org/content/10.1101/156513v1?rss=1 Spadaro, D. Le, S. Laroche, T. Mean, I. Jond, L. Yan, J. Citi, S. 2017-06-27 doi:10.1101/156513 Cold Spring Harbor Laboratory Press 2017-06-27 <![CDATA[ Genome-wide genetic data on ~500,000 UK Biobank participants ]]> https://biorxiv.org/content/10.1101/166298v1?rss=1 Bycroft, C. Freeman, C. Petkova, D. Band, G. Elliott, L. T. Sharp, K. Motyer, A. Vukcevic, D. Delaneau, O. O'Connell, J. Cortes, A. Welsh, S. McVean, G. Leslie, S. Donnelly, P. Marchini, J. 2017-07-20 doi:10.1101/166298 Cold Spring Harbor Laboratory Press 2017-07-20 <![CDATA[ Impact of spatial scale and edge weight on predictive power of cortical thickness networks ]]> https://biorxiv.org/content/10.1101/170381v1?rss=1 Raamana, P. R. Strother, S. C. 2017-07-31 doi:10.1101/170381 Cold Spring Harbor Laboratory Press 2017-07-31 <![CDATA[ Intra- and inter-chromosomal chromatin interactions mediate genetic effects on regulatory networks ]]> https://biorxiv.org/content/10.1101/171694v1?rss=1 Delaneau, O. Zazhytska, M. Borel, C. Howald, C. Kumar, S. Ongen, H. Popadin, K. Marbach, D. Ambrosini, G. Bielser, D. Hacker, D. Romano-Palumbo, L. Ribaux, P. Wiederkehr, M. Falconnet, E. Bucher, P. Bergmann, S. Antonarakis, S. Reymond, A. Dermitzakis, E. 2017-08-03 doi:10.1101/171694 Cold Spring Harbor Laboratory Press 2017-08-03 <![CDATA[ The contributions of the actin machinery to endocytic membrane bending and vesicle formation ]]> https://biorxiv.org/content/10.1101/172072v1?rss=1 Picco, A. Kukulski, W. Manenschijn, H. E. Specht, T. Briggs, J. A. G. Kaksonen, M. 2017-08-03 doi:10.1101/172072 Cold Spring Harbor Laboratory Press 2017-08-03 <![CDATA[ Hundreds of putative non-coding cis-regulatory drivers in chronic lymphocytic leukaemia and skin cancer ]]> https://biorxiv.org/content/10.1101/174219v1?rss=1 Ongen, H. Delaneau, O. Stevens, M. W. Howald, C. Dermitzakis, E. T. 2017-08-09 doi:10.1101/174219 Cold Spring Harbor Laboratory Press 2017-08-09 <![CDATA[ BUSCO applications from quality assessments to gene prediction and phylogenomics ]]> https://biorxiv.org/content/10.1101/177485v1?rss=1 Waterhouse, R. M. Seppey, M. Simao Neto, F. A. Manni, M. Ioannidis, P. Klioutchnikov, G. Kriventseva, E. V. Zdobnov, E. 2017-08-17 doi:10.1101/177485 Cold Spring Harbor Laboratory Press 2017-08-17 <![CDATA[ Early alterations of social brain networks in young children with autism ]]> https://biorxiv.org/content/10.1101/180703v1?rss=1 Sperdin, H. F. Coito, A. Kojovic, N. Rihs, T. A. Jan, R. K. Franchini, M. Plomp, G. Vulliemoz, S. Eliez, S. Michel, C. M. Schaer, M. 2017-08-30 doi:10.1101/180703 Cold Spring Harbor Laboratory Press 2017-08-30 <![CDATA[ Taxon sampling unequally affects individual nodes in a phylogenetic tree: consequences for model gene tree construction in SwissTree ]]> https://biorxiv.org/content/10.1101/181966v1?rss=1 Boeckmann, B. Dylus, D. Moretti, S. Altenhoff, A. Train, C.-M. Kriventseva, E. Bougueleret, L. Xenarios, I. Privman, E. Dessimoz, C. 2017-08-29 doi:10.1101/181966 Cold Spring Harbor Laboratory Press 2017-08-29 <![CDATA[ Toxoplasma gondii microneme proteins 1 and 4 bind to Toll-like receptors 2 and 4 N-glycans triggering innate immune response ]]> https://biorxiv.org/content/10.1101/187690v1?rss=1 Sardinha-Silva, A. Mendonca-Natividade, F. C. Pinzan, C. F. Lopes, C. D. Costa, D. L. Jacot, D. Fernandes, F. F. Zorzetto-Fernandes, A. L. V. Gay, N. J. Sher, A. Jankovic, D. Soldati-Favre, D. Grigg, M. E. Roque-Barreira, M. C. 2017-09-12 doi:10.1101/187690 Cold Spring Harbor Laboratory Press 2017-09-12 <![CDATA[ Deciphering cell lineage specification during male sex determination with single-cell RNA sequencing ]]> https://biorxiv.org/content/10.1101/190264v1?rss=1 Stevant, I. Neirijnck, Y. Borel, C. Escoffier, J. Smith, L. B. Antonarakis, S. E. Dermitzakis, E. T. Nef, S. 2017-09-18 doi:10.1101/190264 Cold Spring Harbor Laboratory Press 2017-09-18 <![CDATA[ The HoxD Cluster is a Dynamic and Resilient TAD Boundary Controling the Segregation of Antagonistic Regulatory Landscapes ]]> https://biorxiv.org/content/10.1101/193706v1?rss=1 Rodriguez-Carballo, E. Lopez-Delisle, L. Zhan, Y. Fabre, P. Beccari, L. El-Idrissi, I. Nguyen Huynh, T. H. Ozadam, H. Dekker, J. Duboule, D. 2017-09-28 doi:10.1101/193706 Cold Spring Harbor Laboratory Press 2017-09-28 <![CDATA[ PSGfinder: fast identification of genes under divergent positive selection using the dynamic windows method ]]> https://biorxiv.org/content/10.1101/193722v1?rss=1 1. PSGfinder additionally includes an alignment cleaning procedure and an adapted multiple comparison correction to identify significant signals of positive selection.nnAvailability and ImplementationPSGfinder is a software that implements the DWin method, is written in Python and is freely available with its documentation at: https://genev.unige.ch/research/laboratory/Juan-Montoya or at: https://github.com/joel-tuberosa/psgfindernnContactjuan.montoya@unige.ch; joel.tuberosa@unige.ch ]]> Tuberosa, J. Montoya-Burgos, J. I. 2017-09-25 doi:10.1101/193722 Cold Spring Harbor Laboratory Press 2017-09-25 <![CDATA[ Linear-Nonlinear-Time-Warp-Poisson models of neural activity ]]> https://biorxiv.org/content/10.1101/194498v1?rss=1 Lawlor, P. N. Perich, M. G. Miller, L. E. Kording, K. P. 2018-01-22 doi:10.1101/194498 Cold Spring Harbor Laboratory Press 2018-01-22 <![CDATA[ Discriminability of numerosity-evoked fMRI activity patterns in human intra-parietal cortex reflects behavioral numerical acuity ]]> https://biorxiv.org/content/10.1101/198002v1?rss=1 Lasne, G. Piazza, M. Dehaene, S. Kleinschmidt, A. Eger, E. 2017-10-05 doi:10.1101/198002 Cold Spring Harbor Laboratory Press 2017-10-05 <![CDATA[ Force-dependent ligand sensing enables αVβ3 integrin to differentiate between fibronectin and high-affinity ligands ]]> https://biorxiv.org/content/10.1101/200493v1?rss=1 Bachmann, M. Schäfer, M. Weissenbruch, K. Mykuliak, V. Heiser, L. Franz, C. M. Hytönen, V. Wehrle-Haller, B. Bastmeyer, M. 2017-10-10 doi:10.1101/200493 Cold Spring Harbor Laboratory Press 2017-10-10 <![CDATA[ Error-prone bypass of DNA lesions during lagging strand replication is a common source of germline and cancer mutations ]]> https://biorxiv.org/content/10.1101/200691v1?rss=1 Seplyarskiy, V. Andrianova, M. A. Nikolaev, S. I. Bazykin, G. A. Sunyaev, S. R. 2017-10-10 doi:10.1101/200691 Cold Spring Harbor Laboratory Press 2017-10-10 <![CDATA[ Molecular evolutionary trends and feeding ecology diversification in the Hemiptera, anchored by the milkweed bug genome ]]> https://biorxiv.org/content/10.1101/201731v1?rss=1 Panfilio, K. A. Vargas Jentzsch, I. M. Benoit, J. B. Erezyilmaz, D. Suzuki, Y. Colella, S. Robertson, H. M. Poelchau, M. F. Waterhouse, R. M. Ioannidis, P. Weirauch, M. T. Hughes, D. S. T. Murali, S. C. Werren, J. H. Jacobs, C. G. C. Duncan, E. J. Armisen, D. Vreede, B. M. I. Baa-Puyoulet, P. Berger, C. S. Chang, C.-c. Chao, H. Chen, M.-J. M. Chen, Y.-T. Childers, C. P. Chipman, A. D. Cridge, A. G. Crumiere, A. J. J. Dearden, P. K. Didion, E. M. Dinh, H. doddapaneni, h. Dolan, A. Dugan-Perez, S. Extavour, C. G. Febvvay, G. Friedrich, M. Ginzburg, N. Han, Y 2017-10-11 doi:10.1101/201731 Cold Spring Harbor Laboratory Press 2017-10-11 <![CDATA[ Inositol pyrophosphates promote the interaction of SPX domains with the coiled-coil motif of PHR transcription factors to regulate plant phosphate homeostasis. ]]> https://biorxiv.org/content/10.1101/2019.12.13.875393v1?rss=1 Ried, M. K. Wild, R. Zhu, J. Broger, L. Harmel, R. K. Hothorn, L. A. Fiedler, D. Hothorn, M. 2019-12-13 doi:10.1101/2019.12.13.875393 Cold Spring Harbor Laboratory Press 2019-12-13 <![CDATA[ Conserved function of ether lipids and sphingolipids in the early secretory pathway ]]> https://biorxiv.org/content/10.1101/2019.12.19.881094v1?rss=1 Jimenez, N. Leonetti, M. Zoni, V. Colom, A. Feng, S. Iyengar, N. R. Matile, S. Roux, A. Vanni, S. Weissman, J. S. Riezman, H. 2019-12-19 doi:10.1101/2019.12.19.881094 Cold Spring Harbor Laboratory Press 2019-12-19 <![CDATA[ A cellular stress response induced by the CRISPR/dCas9 activation system is not heritable through cell divisions ]]> https://biorxiv.org/content/10.1101/2019.12.23.887224v1?rss=1 Johnston, A. D. Abdulrazak, A. Sato, H. Maqbool, S. Suzuki, M. Greally, J. M. Simoes-Pires, C. A. 2019-12-23 doi:10.1101/2019.12.23.887224 Cold Spring Harbor Laboratory Press 2019-12-23 <![CDATA[ Kirrel3-mediated synapse formation is attenuated by disease-associated missense variants ]]> https://biorxiv.org/content/10.1101/2019.12.30.891085v1?rss=1 Taylor, M. R. Martin, E. A. Sinnen, B. Trilokekar, R. Ranza, E. Antonarakis, S. E. Williams, M. E. 2019-12-30 doi:10.1101/2019.12.30.891085 Cold Spring Harbor Laboratory Press 2019-12-30 <![CDATA[ Homogeneous multifocal excitation for high-throughput super-resolution imaging ]]> https://biorxiv.org/content/10.1101/2020.01.08.895565v1?rss=1 100x100 {micro}m2 without compromising image quality, and maintains high-speed (100 Hz), multi-color, volumetric imaging at double the diffraction-limited resolution. We further extend the effective FOV by stitching multiple adjacent images together to perform fast live-cell super-resolution imaging of dozens of cells. Finally, we combine our flat-fielded iSIM setup with ultrastructure expansion microscopy (U-ExM) to collect 3D images of hundreds of centrioles in human cells, as well as of thousands of purified Chlamydomonas reinhardtii centrioles per hour at an effective resolution of [~]35 nm. We apply classification and particle averaging to these large datasets, allowing us to map the 3D organization of post-translational modifications of centriolar microtubules, revealing differences in their coverage and positioning. ]]> Mahecic, D. Gambarotto, D. Douglass, K. M. Fortun, D. Banterle, N. Le Guennec, M. Ibrahim, K. A. Gonczy, P. Hamel, V. Guichard, P. Manley, S. 2020-01-09 doi:10.1101/2020.01.08.895565 Cold Spring Harbor Laboratory Press 2020-01-09 <![CDATA[ Functional heterogeneity in the fermentation capabilities of the healthy human gut microbiota ]]> https://biorxiv.org/content/10.1101/2020.01.17.910638v1?rss=1 Gurry, T. Nguyen, L. T. T. Yu, X. Alm, E. J. 2020-01-24 doi:10.1101/2020.01.17.910638 Cold Spring Harbor Laboratory Press 2020-01-24 <![CDATA[ Linking endoplasmic reticulum stress to polyploidy in ovarian cancer cells ]]> https://biorxiv.org/content/10.1101/2020.01.24.918029v1?rss=1 Yart, L. Bastida-Ruiz, D. wuillemin, c. ribaux, p. allard, m. dietrich, p.-y. petignat, p. cohen, m. 2020-01-24 doi:10.1101/2020.01.24.918029 Cold Spring Harbor Laboratory Press 2020-01-24 <![CDATA[ Extensive fragmentation and re-organization of gene co-expression patterns underlie the progression of Systemic Lupus Erythematosus ]]> https://biorxiv.org/content/10.1101/2020.01.28.922559v1?rss=1 View larger version (29K): org.highwire.dtl.DTLVardef@c9fdfborg.highwire.dtl.DTLVardef@1417da2org.highwire.dtl.DTLVardef@9f229borg.highwire.dtl.DTLVardef@1991569_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Ntasis, V. F. Panousis, N. I. Tektonidou, M. G. Dermitzakis, E. T. Boumpas, D. T. Bertsias, G. K. Nikolaou, C. 2020-01-29 doi:10.1101/2020.01.28.922559 Cold Spring Harbor Laboratory Press 2020-01-29 <![CDATA[ Effect of acute physical exercise on motor sequence memory ]]> https://biorxiv.org/content/10.1101/2020.01.28.922930v1?rss=1 Marin Bosch, B. Bringard, A. Logrieco, M. G. Imobersteg, N. Lauer, E. Thomas, A. Ferretti, G. Schwartz, S. Igloi, K. 2020-01-28 doi:10.1101/2020.01.28.922930 Cold Spring Harbor Laboratory Press 2020-01-28 <![CDATA[ An injectable meta-biomaterial ]]> https://biorxiv.org/content/10.1101/2020.01.30.926931v1?rss=1 Beduer, A. Bonini, F. Bonini, F. Burch, P. Braschler, T. 2020-01-31 doi:10.1101/2020.01.30.926931 Cold Spring Harbor Laboratory Press 2020-01-31 <![CDATA[ Neurothreads: Cryogel carrier-based differentiation and delivery of mature neurons in the treatment of Parkinson's disease ]]> https://biorxiv.org/content/10.1101/2020.01.30.927244v1?rss=1 Filippova, A. Bonini, F. Efremova, L. Preynat-Seauve, O. Beduer, A. Krause, K.-H. Braschler, T. 2020-01-31 doi:10.1101/2020.01.30.927244 Cold Spring Harbor Laboratory Press 2020-01-31 <![CDATA[ Highly efficient cardiac differentiation and maintenance by thrombin-coagulated fibrin hydrogels enriched with decellularized porcine heart extracellular matrix ]]> https://biorxiv.org/content/10.1101/2020.01.30.927319v1?rss=1 Navaee, F. Renaud, P. Braschler, T. 2020-01-31 doi:10.1101/2020.01.30.927319 Cold Spring Harbor Laboratory Press 2020-01-31 <![CDATA[ Spatial transcriptomics of tumor microenvironment in formalin-fixed paraffin-embedded breast cancer ]]> https://biorxiv.org/content/10.1101/2020.01.31.928143v1?rss=1 Romanens, L. Chaskar, P. Tille, J.-C. Ryser, S. Liaudet, N. Hu-Heimgartner, K. Heimgartner, K. Kaya, G. Tsantoulis, P. Labidi-Galy, S. I. 2020-02-02 doi:10.1101/2020.01.31.928143 Cold Spring Harbor Laboratory Press 2020-02-02 <![CDATA[ Internally generated population activity in cortical networks hinders information transmission ]]> https://biorxiv.org/content/10.1101/2020.02.03.932723v1?rss=1 Huang, C. Pouget, A. Doiron, B. D. 2020-02-04 doi:10.1101/2020.02.03.932723 Cold Spring Harbor Laboratory Press 2020-02-04 <![CDATA[ High throughput screening identifies SOX2 as a Super Pioneer Factor that inhibits DNA methylation maintenance at its binding sites ]]> https://biorxiv.org/content/10.1101/2020.02.10.941682v1?rss=1 Vanzan, L. Soldati, H. Ythier, V. Anand, S. Francis, N. J. Murr, R. 2020-02-10 doi:10.1101/2020.02.10.941682 Cold Spring Harbor Laboratory Press 2020-02-10 <![CDATA[ Genome-enabled insights into the biology of thrips as crop pests ]]> https://biorxiv.org/content/10.1101/2020.02.12.941716v1?rss=1 Rotenberg, D. Baumann, A. A. Ben-Mahmoud, S. Christiaens, O. Dermauw, W. Ioannidis, P. Jacobs, C. G. C. Vargas Jentzsch, I. M. Oliver, J. E. Poelchau, M. F. Rajarapu, S. P. Schneweis, D. J. Snoeck, S. Taning, C. N. T. Wei, D. Widana-Gamage, S. M. K. Hughes, D. S. T. Murali, S. C. Bailey, S. Bejerman, N. E. Holmes, C. J. Jennings, E. C. Rosendale, A. J. Rosselot, A. Hervey, K. Schneweis, B. A. Cheng, S. Childers, C. Simao, F. A. Dietzgen, R. G. Chao, H. Dinh, H. Doddapaneni, H. V. Dugan, S. Han, Y. Lee, S. L. Muzny, D. M. Qu, J. Worley, K. C. Benoit, J. B. 2020-02-13 doi:10.1101/2020.02.12.941716 Cold Spring Harbor Laboratory Press 2020-02-13 <![CDATA[ Differential submergence tolerance between juvenile and adult Arabidopsis plants involves the ANAC017 transcription factor ]]> https://biorxiv.org/content/10.1101/2020.02.12.945923v1?rss=1 Bui, L. T. Shukla, V. Giorgi, F. M. Trivellini, A. Perata, P. Licausi, F. Giuntoli, B. 2020-02-13 doi:10.1101/2020.02.12.945923 Cold Spring Harbor Laboratory Press 2020-02-13 <![CDATA[ Global Dynamic Molecular Profiles of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing ]]> https://biorxiv.org/content/10.1101/2020.02.13.947549v1?rss=1 Liu, Z. Zhou, Y. Guo, J. Li, J. Tian, Z. Zhu, Z. Wang, J. Wu, R. Zhang, B. Hu, Y. Sun, Y. Shangguan, Y. Li, W. Li, T. Hu, Y. Guo, C. Rochaix, J.-D. Miao, Y. Sun, X. 2020-02-14 doi:10.1101/2020.02.13.947549 Cold Spring Harbor Laboratory Press 2020-02-14 <![CDATA[ A divergent cyclin/cyclin-dependent kinase complex controls the atypical replication of Plasmodium berghei during gametogony and parasite transmission. ]]> https://biorxiv.org/content/10.1101/2020.02.14.928432v1?rss=1 Balestra, A. C. Zeeshan, M. Rea, E. Pasquarello, C. Klages, N. Mourier, T. Subudhi, A. K. Arboit, P. Brusini, L. A. Pandey, R. Brady, D. Vaughan, S. Holder, A. A. Pain, A. Ferguson, D. Hainard, A. Tewari, R. Brochet, M. 2020-02-14 doi:10.1101/2020.02.14.928432 Cold Spring Harbor Laboratory Press 2020-02-14 <![CDATA[ The inner scaffold protects from centriole fracture ]]> https://biorxiv.org/content/10.1101/2020.02.15.950444v1?rss=1 Steib, E. Gambarotto, D. Laporte, M. H. Olieric, N. Zheng, C. Borgers, S. Olieric, V. Le Guennec, M. Koll, F. Tassin, A.-M. Steinmetz, M. O. Hamel, V. Guichard, P. 2020-02-15 doi:10.1101/2020.02.15.950444 Cold Spring Harbor Laboratory Press 2020-02-15 <![CDATA[ Constitutive activation of leucine-rich repeat receptor kinase signaling pathways by BAK1-interacting receptor-like kinase 3 chimera ]]> https://biorxiv.org/content/10.1101/2020.02.18.954479v1?rss=1 Hohmann, U. Ramakrishna, P. Wang, K. Lorenzo-Orts, L. Nicolet, J. Henschen, A. Barberon, M. Bayer, M. Hothorn, M. 2020-02-19 doi:10.1101/2020.02.18.954479 Cold Spring Harbor Laboratory Press 2020-02-19 <![CDATA[ Two alveolin network proteins are essential for the subpellicular microtubules assembly and conoid anchoring to the apical pole of mature Toxoplasma gondii ]]> https://biorxiv.org/content/10.1101/2020.02.25.962589v1?rss=1 Tosetti, N. Dos Santos Pacheco, N. Bertiaux, E. Maco, B. Bournonville, L. Hamel, V. Guichard, P. Soldati-Favre, D. 2020-02-26 doi:10.1101/2020.02.25.962589 Cold Spring Harbor Laboratory Press 2020-02-26 <![CDATA[ Oxytocin Acts on Astrocytes in the Central Amygdala to Promote a Positive Emotional State ]]> https://biorxiv.org/content/10.1101/2020.02.25.963884v1?rss=1 Wahis, J. Kerspern, D. Althammer, F. Baudon, A. Goyon, S. Hagiwara, D. Lefevre, A. Boury-Jamot, B. Bellanger, B. Abatis, M. Silva da Gouveia, M. Benusiglio, D. Eliava, M. Rozov, A. Weinstanto, I. Knobloch-Bollmann, H. S. Wang, H. Pertin, M. Inquimbert, P. Pitzer, C. Siemens, J. Goumon, Y. Boutrel, B. Darbon, P. Lamy, C. M. Stern, J. E. Decosterd, I. Chatton, J.-Y. Young, S. W. Stoop, R. Poisbeau, P. Grinevich, V. Charlet, A. 2020-02-26 doi:10.1101/2020.02.25.963884 Cold Spring Harbor Laboratory Press 2020-02-26 <![CDATA[ Multiple roles for the ESCRT machinery in maintaining plasma membrane homeostasis ]]> https://biorxiv.org/content/10.1101/2020.02.25.964452v1?rss=1 Schmidt, O. Weyer, Y. Sprenger, S. Widerin, M. A. Eising, S. Baumann, V. Angelova, M. Loewith, R. Stefan, C. J. Hess, M. W. Froehlich, F. Teis, D. 2020-02-26 doi:10.1101/2020.02.25.964452 Cold Spring Harbor Laboratory Press 2020-02-26 <![CDATA[ Low expression of ANT1 confers oncogenic properties to rhabdomyosarcoma tumor cells via modulating metabolism and death pathways. ]]> https://biorxiv.org/content/10.1101/2020.03.03.973719v1?rss=1 Vial, J. Huchede, P. Fagault, S. Basset, F. Rossi, M. Geoffray, J. Bisaccia, J. Creveaux, M. Neves, D. Fauvelle, F. Castets, P. Carre, M. Weber, K. Castets, M. 2020-03-05 doi:10.1101/2020.03.03.973719 Cold Spring Harbor Laboratory Press 2020-03-05 <![CDATA[ The polymorphism of Hydra satellite sequences provides strain-specific signatures ]]> https://biorxiv.org/content/10.1101/2020.03.04.977470v1?rss=1 Galliot, B. Schenkelaars, Q. Perez-Cortez, D. Perruchoud, C. 2020-03-06 doi:10.1101/2020.03.04.977470 Cold Spring Harbor Laboratory Press 2020-03-06 <![CDATA[ Autoregulation clamps the synaptic membrane-remodeling machinery and promotes productive actin-dependent endocytosis ]]> https://biorxiv.org/content/10.1101/2020.03.06.981076v1?rss=1 Del Signore, S. J. Kelley, C. F. Messelaar, E. M. Lemos, T. Marchan, M. F. Mund, M. Kaksonen, M. Rodal, A. A. 2020-03-07 doi:10.1101/2020.03.06.981076 Cold Spring Harbor Laboratory Press 2020-03-07 <![CDATA[ Unravelling the phylogenomic relationships of the most diverse African palm genus Raphia (Calamoideae, Arecaceae) ]]> https://biorxiv.org/content/10.1101/2020.03.09.984351v1?rss=1 Helmstetter, A. J. Bethune, K. Lautenschlaeger, T. Bacon, C. D. Stauffer, F. Antonelli, A. Sonke, B. Couvreur, T. L. P. 2020-03-11 doi:10.1101/2020.03.09.984351 Cold Spring Harbor Laboratory Press 2020-03-11 <![CDATA[ Molecular resolution imaging by post-labeling expansion single molecule localization microscopy (Ex-SMLM) ]]> https://biorxiv.org/content/10.1101/2020.03.12.988923v1?rss=1 Zwettler, F. U. Reinhard, S. Gambarotto, D. Bell, T. D. M. Hamel, V. Guichard, P. Sauer, M. 2020-03-13 doi:10.1101/2020.03.12.988923 Cold Spring Harbor Laboratory Press 2020-03-13 <![CDATA[ Increased random exploration in schizophrenia is associated with inflammation ]]> https://biorxiv.org/content/10.1101/2020.03.15.989483v1?rss=1 Cathomas, F. Klaus, F. Guetter, K. Chung, H.-K. Raja Beharelle, A. Spiller, T. Schlegel, R. Seifritz, E. Hartmann-Riemer, M. Tobler, P. N. Kaiser, S. 2020-03-17 doi:10.1101/2020.03.15.989483 Cold Spring Harbor Laboratory Press 2020-03-17 <![CDATA[ Microbial contaminants cataloged as novel human sequences in recent human pan-genomes ]]> https://biorxiv.org/content/10.1101/2020.03.16.994376v1?rss=1 40 aa). The major sources of contamination are related to Rhyzobiales, Burkholderiales, Pseudomonadales and Lactobacillales, which may have been associated with the original samples or introduced later during sequencing experiments. We additionally observed that the majority of human novel protein-coding genes described in one of the studies entirely overlap repetitive regions and are likely to be false positive predictions. We report here the list of contaminant sequences in three recent human pan-genome catalogues and discuss strategies to increase decontamination efficacy for current and future pan-genome studies. ]]> Manni, M. Zdobnov, E. M. 2020-03-18 doi:10.1101/2020.03.16.994376 Cold Spring Harbor Laboratory Press 2020-03-18 <![CDATA[ Non-Toxic Virucidal Macromolecules Show High Efficacy Against Influenza Virus Ex Vivo and In Vivo ]]> https://biorxiv.org/content/10.1101/2020.03.18.996678v1?rss=1 Kocabiyik, O. Cagno, V. Sedano, L. Bhide, Y. Mettier, J. Medaglia, C. Da Costa, B. Zhu, Y. Constant, S. Huang, S. Kaiser, L. Hinrichs, W. Huckriede, A. Le Goffic, R. Tapparel, C. Stellacci, F. 2020-03-18 doi:10.1101/2020.03.18.996678 Cold Spring Harbor Laboratory Press 2020-03-18 <![CDATA[ A transient decrease in mitochondrial activity is required to establish the ganglion cell fate in retina adapted for high acuity vision ]]> https://biorxiv.org/content/10.1101/2020.03.23.002998v1?rss=1 View larger version (25K): org.highwire.dtl.DTLVardef@60b51aorg.highwire.dtl.DTLVardef@111be27org.highwire.dtl.DTLVardef@1db19f8org.highwire.dtl.DTLVardef@1860da3_HPS_FORMAT_FIGEXP M_FIG GRAPHICAL ABSTRACT C_FIG ]]> Brodier, L. Rodrigues, T. Matter-Sadzinski, L. Matter, J.-M. 2020-03-23 doi:10.1101/2020.03.23.002998 Cold Spring Harbor Laboratory Press 2020-03-23 <![CDATA[ SARS-CoV-2 receptor and entry genes are expressed by sustentacular cells in the human olfactory neuroepithelium ]]> https://biorxiv.org/content/10.1101/2020.03.31.013268v1?rss=1 Fodoulian, L. Tuberosa, J. Rossier, D. Landis, B. Carleton, A. Rodriguez, I. 2020-04-02 doi:10.1101/2020.03.31.013268 Cold Spring Harbor Laboratory Press 2020-04-02 <![CDATA[ Selective enhancement of low-gamma activity by tACS improves phonemic processing and reading accuracy in dyslexia ]]> https://biorxiv.org/content/10.1101/2020.04.15.042770v1?rss=1 Marchesotti, S. Nicolle, J. Merlet, I. Arnal, L. H. Donoghue, J. P. Giraud, A.-L. 2020-04-17 doi:10.1101/2020.04.15.042770 Cold Spring Harbor Laboratory Press 2020-04-17 <![CDATA[ Leigh Syndrome-inducing Mutations Affect LRPPRC / SLIRP Complex Formation ]]> https://biorxiv.org/content/10.1101/2020.04.16.044412v1?rss=1 Coquille, S. Thore, S. 2020-04-18 doi:10.1101/2020.04.16.044412 Cold Spring Harbor Laboratory Press 2020-04-18 <![CDATA[ Sorcin stimulates Activation Transcription Factor 6α (ATF6) transcriptional activity ]]> https://biorxiv.org/content/10.1101/2020.04.23.053322v1?rss=1 Parks, S. Gao, T. Jimenez Awuapura, N. Ayathamattam, J. Chabosseau, P. L. Marchetti, P. Johnson, P. Bosco, D. Kalvakolanu, D. V. Valdivia, H. H. Rutter, G. A. Leclerc, I. 2020-04-24 doi:10.1101/2020.04.23.053322 Cold Spring Harbor Laboratory Press 2020-04-24 <![CDATA[ Self-reported sleep problems are related to cortical thinning in aging but not memory decline and amyloid-β accumulation - results from the Lifebrain consortium ]]> https://biorxiv.org/content/10.1101/2020.04.28.065474v1?rss=1 Fjell, A. Sorensen, O. Amlien, I. K. Bartres-Faz, D. Brandmaier, A. Macia, D. Buchmann, N. Demuth, I. Drevon, C. A. Duzel, S. Ebmeier, K. Ghisletta, P. Idland, A.-V. Kietzmann, T. Kievit, R. A. Kuhn, S. A. Lindenberger, U. Magnussen, F. Mowinckel, A. M. Nyberg, L. Roe, J. M. Sexton, C. Sole-Padulles, C. Pudas, S. Vidal-Pineiro, D. Sederevicius, D. Suri, S. Wagner, G. Watne, L. O. Westerhausen, R. Zsoldos, E. Walhovd, K. B. 2020-04-28 doi:10.1101/2020.04.28.065474 Cold Spring Harbor Laboratory Press 2020-04-28 <![CDATA[ Spontaneous network coupling enables efficient task performance without local task-induced activations ]]> https://biorxiv.org/content/10.1101/2020.05.04.075804v1?rss=1 Allaman, L. Mottaz, A. Kleinschmidt, A. Guggisberg, A. G. 2020-05-05 doi:10.1101/2020.05.04.075804 Cold Spring Harbor Laboratory Press 2020-05-05 <![CDATA[ Single-cell immune repertoire and transcriptome sequencing reveals that clonally expanded and transcriptionally distinct lymphocytes populate the aged central nervous system in mice ]]> https://biorxiv.org/content/10.1101/2020.05.04.077081v1?rss=1 Yermanos, A. Neumeier, D. Sandu, I. Borsa, M. Waindok, A. C. Merkler, D. Oxenius, A. Reddy, S. T. 2020-05-05 doi:10.1101/2020.05.04.077081 Cold Spring Harbor Laboratory Press 2020-05-05 <![CDATA[ AI334 and AQ806 antibodies recognize the spike S protein from SARS-CoV-2 by ELISA ]]> https://biorxiv.org/content/10.1101/2020.05.08.084103v1?rss=1 Lima, W. C. 2020-05-08 doi:10.1101/2020.05.08.084103 Cold Spring Harbor Laboratory Press 2020-05-08 <![CDATA[ Naturally acquired blocking human monoclonal antibodies to Plasmodium vivax reticulocyte binding protein 2b ]]> https://biorxiv.org/content/10.1101/2020.05.12.091900v1?rss=1 Chan, L.-J. Gandhirajan, A. Carias, L. L. Dietrich, M. H. Vadas, O. Visentin, R. Franca, C. T. Menant, S. Soldati-Favre, D. Mueller, I. King, C. L. Tham, W.-H. 2020-05-13 doi:10.1101/2020.05.12.091900 Cold Spring Harbor Laboratory Press 2020-05-13 <![CDATA[ Achieving High-Resolution Whole-Brain Slab 1H-MRSI with Compressed-Sensing and Low-Rank Reconstruction at 7 Tesla ]]> https://biorxiv.org/content/10.1101/2020.05.13.092668v1?rss=1 Klauser, A. Strasser, B. Thapa, B. Lazeyras, F. Andronesi, O. 2020-05-15 doi:10.1101/2020.05.13.092668 Cold Spring Harbor Laboratory Press 2020-05-15 <![CDATA[ Cingulin unfolds ZO-1 and organizes myosin-2B and gamma-actin to mechanoregulate apical and tight junction membranes ]]> https://biorxiv.org/content/10.1101/2020.05.14.095364v1?rss=1 Vasileva, E. Rouaud, F. Spadaro, D. Huang, W. Colom, A. Flinois, A. Shah, J. Dugina, V. Chaponnier, C. Sluysmans, S. Mean, I. Jond, L. Roux, A. Yan, J. Citi, S. 2020-05-15 doi:10.1101/2020.05.14.095364 Cold Spring Harbor Laboratory Press 2020-05-15 <![CDATA[ Tannic cell walls form a continuous apoplastic barrier sustaining Arabidopsis seed coat biophysical properties ]]> https://biorxiv.org/content/10.1101/2020.05.14.096669v1?rss=1 Demonsais, L. Utz-Pugin, A. Loubery, S. Lopez-Molina, L. 2020-05-17 doi:10.1101/2020.05.14.096669 Cold Spring Harbor Laboratory Press 2020-05-17 <![CDATA[ Whole-Brain High-Resolution Metabolite Mapping with 3D Compressed-Sensing-SENSE-LowRank 1H FID-MRSI ]]> https://biorxiv.org/content/10.1101/2020.05.18.101618v1?rss=1 Klauser, A. Klauser, P. Grouiller, F. Courvoisier, S. Lazeyras, F. 2020-05-20 doi:10.1101/2020.05.18.101618 Cold Spring Harbor Laboratory Press 2020-05-20 <![CDATA[ An unconventional cerebrospinal fluid-derived Semaphorin-signalling regulates apical progenitor dynamics in the developing neocortex ]]> https://biorxiv.org/content/10.1101/2020.05.20.106526v1?rss=1 GERSTMANN, K. KINDBEITER, K. TELLEY, L. BOZON, M. CHAROY, C. JABAUDON, D. MORET, F. CASTELLANI, V. 2020-05-23 doi:10.1101/2020.05.20.106526 Cold Spring Harbor Laboratory Press 2020-05-23 <![CDATA[ Dopamine neurons of the VTA encode active conspecific interaction and promote social learning through social reward prediction error. ]]> https://biorxiv.org/content/10.1101/2020.05.27.118851v1?rss=1 Prevost-Solie, C. Girard, B. Righetti, B. Tapparel, M. Bellone, C. 2020-05-27 doi:10.1101/2020.05.27.118851 Cold Spring Harbor Laboratory Press 2020-05-27 <![CDATA[ Compensatory ion transport buffers daily protein rhythms to regulate osmotic balance and cellular physiology ]]> https://biorxiv.org/content/10.1101/2020.05.28.118398v1?rss=1 Stangherlin, A. Wong, D. C. S. Barbiero, S. Watson, J. L. Zeng, A. Seinkmane, E. Chew, S. P. Beale, A. D. Hayter, E. A. Guna, A. Inglis, A. Bartolami, E. Matile, S. Lequeux, N. Pons, T. Day, J. van Ooijen, G. Voorhees, R. M. Bechtold, D. Derivery, E. Edgar, R. S. Newham, P. O'Neill, J. S. 2020-05-28 doi:10.1101/2020.05.28.118398 Cold Spring Harbor Laboratory Press 2020-05-28 <![CDATA[ Control of microglial dynamics by Arp2/3 and the autism and schizophrenia-associated protein Cyfip1 ]]> https://biorxiv.org/content/10.1101/2020.05.31.124941v1?rss=1 Drew, J. Arancibia-Carcamo, L. Jolivet, R. B. Lopez-Domenech, G. Attwell, D. Kittler, J. T. 2020-06-01 doi:10.1101/2020.05.31.124941 Cold Spring Harbor Laboratory Press 2020-06-01 <![CDATA[ TMEM106B and CPOX are genetic determinants of cerebrospinal fluid Alzheimer's disease biomarker levels ]]> https://biorxiv.org/content/10.1101/2020.05.31.125633v1?rss=1 Hong, S. Dobricic, V. Bos, I. Vos, S. J. B. Prokopenko, D. Tijms, B. M. Andreasson, U. Blennow, K. Vandenberghe, R. Gabel, S. Scheltens, P. Teunissen, C. E. Engelborghs, S. Frisoni, G. Blin, O. Richardson, J. C. Bordet, R. Lleo, A. Alcolea, D. Popp, J. Clark, C. Peyratout, G. Martinez-Lage, P. Tainta, M. Dobson, R. J. B. Legido-Quigley, C. Sleegers, K. Broeckhoven, C. V. Tanzi, R. E. Kate, M. t. Wittig, M. Franke, A. Barkhof, F. Lovestone, S. Streffer, J. Zetterberg, H. Visser, P. J. Bertram, L. 2020-06-01 doi:10.1101/2020.05.31.125633 Cold Spring Harbor Laboratory Press 2020-06-01 <![CDATA[ Comparative performance of mutual information and transfer entropy for analyzing the balance of information flow and energy consumption at synapses ]]> https://biorxiv.org/content/10.1101/2020.06.01.127399v1?rss=1 Conrad, M. Jolivet, R. B. 2020-06-01 doi:10.1101/2020.06.01.127399 Cold Spring Harbor Laboratory Press 2020-06-01 <![CDATA[ Integer topological defects organize stresses driving tissue morphogenesis ]]> https://biorxiv.org/content/10.1101/2020.06.02.129262v1?rss=1 Guillamat, P. Blanch-Mercader, C. Kruse, K. Roux, A. 2020-06-02 doi:10.1101/2020.06.02.129262 Cold Spring Harbor Laboratory Press 2020-06-02 <![CDATA[ SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways ]]> https://biorxiv.org/content/10.1101/2020.06.08.140079v1?rss=1 Serbyn, N. Bagdiul, I. Michel, A. H. Suhandynata, R. T. Zhou, H. Kornmann, B. Stutz, F. 2020-06-09 doi:10.1101/2020.06.08.140079 Cold Spring Harbor Laboratory Press 2020-06-09 <![CDATA[ SPECIFIC ECTODERMAL ENHANCERS CONTROL THE EXPRESSION OF HoxC GENES IN DEVELOPING MAMMALIAN INTEGUMENTS ]]> https://biorxiv.org/content/10.1101/2020.06.10.143677v1?rss=1 Fernandez-Guerrero, M. Yakushiji-Kaminatsui, N. Lopez-Delisle, L. Zdral, S. Darbellay, F. Perez-Gomez, R. Bolt, C. C. Sanchez-Martin, M. A. Duboule, D. Ros, M. A. 2020-06-10 doi:10.1101/2020.06.10.143677 Cold Spring Harbor Laboratory Press 2020-06-10 <![CDATA[ Brain networks subserving functional core processes of emotions identified with componential modelling ]]> https://biorxiv.org/content/10.1101/2020.06.10.145201v1?rss=1 Mohammadi, G. Van De Ville, D. Vuilleumier, P. 2020-06-12 doi:10.1101/2020.06.10.145201 Cold Spring Harbor Laboratory Press 2020-06-12 <![CDATA[ The alternative sigma factor σX mediates competence shut-off at the cell pole in Streptococcus pneumoniae. ]]> https://biorxiv.org/content/10.1101/2020.06.12.147637v1?rss=1 Johnston, C. H. G. Soulet, A.-L. Berge, M. Prudhomme, M. De Lemos, D. Polard, P. 2020-06-12 doi:10.1101/2020.06.12.147637 Cold Spring Harbor Laboratory Press 2020-06-12 <![CDATA[ Spike-frequency adaptation is modulated by interacting currents in an Hodgkin-Huxley-type model: Role of the Na,K-ATPase ]]> https://biorxiv.org/content/10.1101/2020.06.12.148437v1?rss=1 Jolivet, R. B. Magistretti, P. J. 2020-06-13 doi:10.1101/2020.06.12.148437 Cold Spring Harbor Laboratory Press 2020-06-13 <![CDATA[ Granger-Causal Testing for Irregularly Sampled Time Series with Application to Nitrogen Signaling in Arabidopsis ]]> https://biorxiv.org/content/10.1101/2020.06.15.152819v1?rss=1 Heerah, S. Molinari, R. Guerrier, S. Marshall-Colon, A. 2020-06-17 doi:10.1101/2020.06.15.152819 Cold Spring Harbor Laboratory Press 2020-06-17 <![CDATA[ EEG and fMRI connectomes are reliably related: a simultaneous EEG-fMRI study from 1.5T to 7T ]]> https://biorxiv.org/content/10.1101/2020.06.16.154625v1?rss=1 Wirsich, J. Jorge, J. Iannotti, G. R. Shamshiri, E. A. Grouiller, F. Abreu, R. Lazeyras, F. Giraud, A.-L. Gruetter, R. Sadaghiani, S. Vulliemoz, S. 2020-06-17 doi:10.1101/2020.06.16.154625 Cold Spring Harbor Laboratory Press 2020-06-17 <![CDATA[ Cryptosporulation in Kurthia spp. forces a rethinking of asporogenesis in Firmicutes ]]> https://biorxiv.org/content/10.1101/2020.06.18.160689v1?rss=1 Filippidou, S. Fatton, M. Junier, T. Berge, M. Poppleton, D. Blum, T. B. Kaminek, M. Odriozola, A. Blom, J. Johnson, S. L. Abrahams, J. P. Chain, P. S. G. Gribaldo, S. Tocheva, E. I. Zuber, B. Viollier, P. H. Junier, P. 2020-06-20 doi:10.1101/2020.06.18.160689 Cold Spring Harbor Laboratory Press 2020-06-20 <![CDATA[ LATER but FORTIOR: diffusion modelling of inhibition of return ]]> https://biorxiv.org/content/10.1101/2020.06.21.163485v1?rss=1 Seidel Malkinson, T. Bourgeois, A. Wattiez, N. Pouget, P. Bartolomeo, P. 2020-06-22 doi:10.1101/2020.06.21.163485 Cold Spring Harbor Laboratory Press 2020-06-22 <![CDATA[ Connectome spectral analysis to track EEG task dynamics on a subsecond scale ]]> https://biorxiv.org/content/10.1101/2020.06.22.164111v1?rss=1 Glomb, K. Rue Queralt, J. Pascucci, D. Defferrard, M. Tourbier, S. Carboni, M. Rubega, M. Vulliemoz, S. Plomp, G. Hagmann, P. 2020-06-23 doi:10.1101/2020.06.22.164111 Cold Spring Harbor Laboratory Press 2020-06-23 <![CDATA[ Hapln1b organizes the ECM to modulate kit signaling and control developmental hematopoiesis in zebrafish ]]> https://biorxiv.org/content/10.1101/2020.06.23.161406v1?rss=1 Mahony, C. Pasche, C. Braunersreuther, V. Savvides, S. Deagostini, A. Bertrand, J. 2020-06-23 doi:10.1101/2020.06.23.161406 Cold Spring Harbor Laboratory Press 2020-06-23 <![CDATA[ PlexinA4-Semaphorin3A mediated crosstalk between main cortical interneuron classes is required for superficial interneurons lamination ]]> https://biorxiv.org/content/10.1101/2020.06.23.166926v1?rss=1 Limoni, G. Niquille, M. Murthy, S. Jabaudon, D. Dayer, A. 2020-06-24 doi:10.1101/2020.06.23.166926 Cold Spring Harbor Laboratory Press 2020-06-24 <![CDATA[ Characterization of the Novel Mitochondrial Genome Segregation Factor TAP110 in Trypanosoma brucei ]]> https://biorxiv.org/content/10.1101/2020.06.25.171090v1?rss=1 669 kDa complex. Summary StatementTAP110 is a novel mitochondrial genome segregation factor in Trypanosoma brucei that associates with the previously described TAC component TAC102. Ultrastructure expansion microscopy reveals its proximal position to the kDNA. ]]> Amodeo, S. Kalichava, A. Fradera-Sola, A. Bertiaux, E. Guichard, P. Butter, F. Ochsenreiter, T. 2020-06-26 doi:10.1101/2020.06.25.171090 Cold Spring Harbor Laboratory Press 2020-06-26 <![CDATA[ SUV39 SET domains mediate crosstalk of heterochromatic histone marks ]]> https://biorxiv.org/content/10.1101/2020.06.30.177071v1?rss=1 Stirpe, A. Guidotti, N. Northall, S. Hainard, A. Vadas, O. Fierz, B. Schalch, T. Kilic, S. 2020-07-02 doi:10.1101/2020.06.30.177071 Cold Spring Harbor Laboratory Press 2020-07-02 <![CDATA[ Co-expressed subunits of dual genetic origin define a conserved supercomplex mediating essential protein import into chloroplasts ]]> https://biorxiv.org/content/10.1101/2020.07.04.188128v1?rss=1 Ramundo, S. Asakura, Y. Salomé, P. A. A. Strenkert, D. Boone, M. Mackinder, L. C. M. Takafuji, K. Dinc, E. Rahire, M. Crèvecoeur, M. Magneschi, L. Schaad, O. Hippler, M. Jonikas, M. C. Merchant, S. Nakai, M. Rochaix, J.-D. Walter, P. 2020-07-06 doi:10.1101/2020.07.04.188128 Cold Spring Harbor Laboratory Press 2020-07-06 <![CDATA[ CHO/LY-B cell growth under limiting sphingolipid supply: correlation between lipid composition and biophysical properties of sphingolipid-restricted cell membranes ]]> https://biorxiv.org/content/10.1101/2020.07.05.188474v1?rss=1 Monasterio, B. G. Jimenez-Rojo, N. Garcia-Arribas, A. B. Riezman, H. Goni, F. M. Alonso, A. 2020-07-06 doi:10.1101/2020.07.05.188474 Cold Spring Harbor Laboratory Press 2020-07-06 <![CDATA[ Expansion Microscopy provides new insights into the cytoskeleton of malaria parasites including the conservation of a conoid ]]> https://biorxiv.org/content/10.1101/2020.07.08.192328v1?rss=1 Eloïse Bertiaux Aurélia C Balestra Lorène Bournonville Mathieu Brochet Paul Guichard Virginie Hamel 2020-07-08 doi:10.1101/2020.07.08.192328 Cold Spring Harbor Laboratory Press 2020-07-08 <![CDATA[ NREM sleep stages specifically alter dynamical integration of large-scale brain networks ]]> https://biorxiv.org/content/10.1101/2020.07.08.193508v1?rss=1 Anjali Tarun Danyal Wainstein-Andriano Virginie Sterpenich Laurence Bayer Lampros Perogamvros Mark Solms Nikolai Axmacher Sophie Schwartz Dimitri Van De Ville 2020-07-09 doi:10.1101/2020.07.08.193508 Cold Spring Harbor Laboratory Press 2020-07-09 <![CDATA[ Regulation of GluA1 Phosphorylation by D-amphetamine and Methylphenidate in the Cerebellum ]]> https://biorxiv.org/content/10.1101/2020.07.10.196766v1?rss=1 Laura Cutando Ruiz Emma Puighermanal Laia Castell Pauline Tarot Federica Bertaso Patricia Bonnavion Alban de Kerchove d'Exaerde Elsa Isingrini Micaela Galante Glenn Dallerac Vincent Pascoli Christian Luscher Bruno Giros Emmanuel Valjent 2020-07-10 doi:10.1101/2020.07.10.196766 Cold Spring Harbor Laboratory Press 2020-07-10 <![CDATA[ Chromatin Topology And The Timing Of Enhancer Function At The HoxD Locus ]]> https://biorxiv.org/content/10.1101/2020.07.12.199109v1?rss=1 Edgardo Rodriguez-Carballo Lucille Lopez-Delisle Andrea Willemin Leonardo Beccari Sandra Gitto Benedicte Mascrez Denis Duboule 2020-07-12 doi:10.1101/2020.07.12.199109 Cold Spring Harbor Laboratory Press 2020-07-12 <![CDATA[ An increase in dendritic plateau potentials is associated with experience-dependent cortical map reorganization ]]> https://biorxiv.org/content/10.1101/2020.07.13.200923v1?rss=1 Pages, S. Chenouard, N. Chereau, R. Kouskoff, V. Gambino, F. Holtmaat, A. 2020-07-14 doi:10.1101/2020.07.13.200923 Cold Spring Harbor Laboratory Press 2020-07-14 <![CDATA[ AraC mutations that suppress inactivating mutations in the C-terminal domain of the RpoA subunit of Escherichia coli RNA polymerase ]]> https://biorxiv.org/content/10.1101/2020.07.15.203596v1?rss=1 Belin, D. Silva, F. 2020-07-15 doi:10.1101/2020.07.15.203596 Cold Spring Harbor Laboratory Press 2020-07-15 <![CDATA[ Novel features of centriole polarity and cartwheel stacking revealed by cryo-tomography ]]> https://biorxiv.org/content/10.1101/2020.07.17.208082v1?rss=1 Nazarov, S. Bezler, A. Hatzopoulos, G. Nemcikova Villimova, V. Demurtas, D. Le Guennec, M. Guichard, P. Gönczy, P. 2020-07-18 doi:10.1101/2020.07.17.208082 Cold Spring Harbor Laboratory Press 2020-07-18 <![CDATA[ A multipass membrane protein interacts with the cGMP-dependent protein kinase to regulate critical calcium signals in malaria parasites ]]> https://biorxiv.org/content/10.1101/2020.07.18.209973v1?rss=1 Balestra, A. C. Koussis, K. Klages, N. Howell, S. A. Flynn, H. R. Bantscheff, M. Pasquarello, C. Perrin, A. J. Brusini, L. Arboit, P. Sanz, O. Peces-Barba Castano, L. Withers-Martinez, C. Hainard, A. Ghidelli-Disse, S. Snijders, A. P. Baker, D. A. Blackman, M. J. Brochet, M. 2020-07-18 doi:10.1101/2020.07.18.209973 Cold Spring Harbor Laboratory Press 2020-07-18 <![CDATA[ ALG-2 interacting protein-X (Alix) is required for activity-dependent bulk endocytosis at brain synapses ]]> https://biorxiv.org/content/10.1101/2020.07.20.211854v1?rss=1 Laporte, M. H. Chi, K. I. Rolland, M. Caudal, L. C. Martinez-Hernandez, J. Martineau, M. Chatellard, C. Denarier, E. Mercier, V. Lemaitre, F. Blot, B. Moutaux, E. Cazorla, M. Buisson, A. Perrais, D. Fraboulet, S. Lante, F. Kirchhoff, F. Hemming, F. J. Sadoul, R. 2020-07-22 doi:10.1101/2020.07.20.211854 Cold Spring Harbor Laboratory Press 2020-07-22 <![CDATA[ The architecture of the centriole cartwheel-containing region revealed by cryo-electron tomography ]]> https://biorxiv.org/content/10.1101/2020.07.21.068882v1?rss=1 Klena, N. Le Guennec, M. Tassin, A.-M. van den Hoek, H. Erdmann, P. S. Schaffer, M. Geimer, S. Aeschlimann, G. Kovacik, L. Goldie, K. N. Stahlberg, H. Engel, B. D. Hamel, V. Guichard, P. 2020-07-22 doi:10.1101/2020.07.21.068882 Cold Spring Harbor Laboratory Press 2020-07-22 <![CDATA[ Brain activation lateralization in monkeys (Papio Anubis) following asymmetric motor and auditory stimulations through functional Near Infrared Spectroscopy ]]> https://biorxiv.org/content/10.1101/2020.07.23.217760v1?rss=1 Debracque, C. Gruber, T. Lacoste, R. Grandjean, D. Meguerditchian, A. 2020-07-24 doi:10.1101/2020.07.23.217760 Cold Spring Harbor Laboratory Press 2020-07-24 <![CDATA[ Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor ]]> https://biorxiv.org/content/10.1101/2020.07.24.219246v1?rss=1 Miozzo, F. Stickley, L. Tas, D. Loncle, N. Nikonenko, I. Dorcikova, M. Valencia-Alarcon, E. P. Bou Dib, P. Nagoshi, E. 2020-07-25 doi:10.1101/2020.07.24.219246 Cold Spring Harbor Laboratory Press 2020-07-25 <![CDATA[ Expression of Wnt5a defines the major progenitors of fetal and adult Leydig cells ]]> https://biorxiv.org/content/10.1101/2020.07.25.221069v1?rss=1 Ademi, H. Stevant, I. Rands, C. M. Nef, S. Conne, B. 2020-07-26 doi:10.1101/2020.07.25.221069 Cold Spring Harbor Laboratory Press 2020-07-26 <![CDATA[ Motor cortical dynamics are shaped by multiple distinct subspaces during naturalistic behavior ]]> https://biorxiv.org/content/10.1101/2020.07.30.228767v1?rss=1 Perich, M. G. Conti, S. Badi, M. Bogaard, A. Barra, B. Wurth, S. Bloch, J. Courtine, G. Micera, S. Capogrosso, M. Milekovic, T. 2020-07-31 doi:10.1101/2020.07.30.228767 Cold Spring Harbor Laboratory Press 2020-07-31 <![CDATA[ A constitutively monomeric UVR8 photoreceptor allele confers enhanced UV-B photomorphogenesis ]]> https://biorxiv.org/content/10.1101/2020.08.02.233007v1?rss=1 Podolec, R. Lau, K. Wagnon, T. B. Hothorn, M. Ulm, R. 2020-08-03 doi:10.1101/2020.08.02.233007 Cold Spring Harbor Laboratory Press 2020-08-03 <![CDATA[ Crystal structures of Arabidopsis and Physcomitrella CR4 reveal the molecular architecture of CRINKLY4 receptor kinases. ]]> https://biorxiv.org/content/10.1101/2020.08.10.245050v1?rss=1 Okuda, S. Hothorn, L. A. Hothorn, M. 2020-08-10 doi:10.1101/2020.08.10.245050 Cold Spring Harbor Laboratory Press 2020-08-10 <![CDATA[ Kinesin-1 motility traced by an activity-based precipitating dye ]]> https://biorxiv.org/content/10.1101/2020.08.12.247544v1?rss=1 Angerani, S. Lindberg, E. Klena, N. Bleck, C. K. E. Aumeier, C. Winssinger, N. 2020-08-12 doi:10.1101/2020.08.12.247544 Cold Spring Harbor Laboratory Press 2020-08-12 <![CDATA[ Methylene Blue has a potent antiviral activity against SARS-CoV-2 in the absence of UV-activation in vitro ]]> https://biorxiv.org/content/10.1101/2020.08.14.251090v1?rss=1 Cagno, V. Medaglia, C. Cerny, A. Cerny, T. Tapparel, C. Cerny, E. 2020-08-14 doi:10.1101/2020.08.14.251090 Cold Spring Harbor Laboratory Press 2020-08-14 <![CDATA[ Humanization of Drosophila Gαo to model GNAO1 paediatric encephalopathies ]]> https://biorxiv.org/content/10.1101/2020.08.14.251173v1?rss=1 Savitsky, M. Solis, G. P. Katanaev, V. L. 2020-08-14 doi:10.1101/2020.08.14.251173 Cold Spring Harbor Laboratory Press 2020-08-14 <![CDATA[ Adrenomedullin-CALCRL Axis Controls Relapse-Initiating Drug Tolerant Acute Myeloid Leukemia Cells ]]> https://biorxiv.org/content/10.1101/2020.08.17.253542v1?rss=1 Larrue, C. Guiraud, N. Mouchel, P.-L. Dubois, M. Farge, T. Gotanegre, M. Bosc, C. Saland, E. Travers-Nicolau, M.-L. Sabatier, M. Serhan, N. Sahal, A. Boet, E. Mouche, S. Heydt, Q. Aroua, N. Stuani, L. Kaoma, T. Angenendt, L. Mikesch, J.-H. Schliemann, C. Vergez, F. Tamburini, J. Recher, C. Sarry, J.-E. 2020-08-17 doi:10.1101/2020.08.17.253542 Cold Spring Harbor Laboratory Press 2020-08-17 <![CDATA[ Mitochondrial determinants of response and resistance to venetoclax plus cytarabine duplet therapy in acute myeloid leukemia ]]> https://biorxiv.org/content/10.1101/2020.08.17.253856v1?rss=1 Bosc, C. Gadaud, N. Bousard, A. Sabatier, M. Cognet, G. Saland, E. Farge, T. Boet, E. Gotanegre, M. Aroua, N. Mouchel, P.-L. Larrue, C. Jarrou, L. Rambow, F. Cabon, F. Nicot, N. Vergez, F. Tamburini, J. Fournie, J.-J. Kaoma, T. Marine, J.-C. Recher, C. Stuani, L. Joffre, C. Sarry, J.-E. 2020-08-17 doi:10.1101/2020.08.17.253856 Cold Spring Harbor Laboratory Press 2020-08-17 <![CDATA[ Deep Graph Pose: a semi-supervised deep graphical model for improved animal pose tracking ]]> https://biorxiv.org/content/10.1101/2020.08.20.259705v1?rss=1 Wu, A. Buchanan, E. K. Whiteway, M. R. Schartner, M. Meijer, G. T. Noel, J.-P. Rodriguez, E. Everett, C. Norovich, A. Schaffer, E. S. Mishra, N. Salzman, C. D. Angelaki, D. E. International Brain Laboratory, T. Cunningham, J. P. Paninski, L. 2020-08-22 doi:10.1101/2020.08.20.259705 Cold Spring Harbor Laboratory Press 2020-08-22 <![CDATA[ Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo ]]> https://biorxiv.org/content/10.1101/2020.08.25.266692v1?rss=1 Solis, G. P. Valnohova, J. Alvarez, C. Katanaev, V. L. 2020-08-26 doi:10.1101/2020.08.25.266692 Cold Spring Harbor Laboratory Press 2020-08-26 <![CDATA[ Cold Exposure Protects from Neuroinflammation Through Immunologic Reprogramming ]]> https://biorxiv.org/content/10.1101/2020.08.28.269563v1?rss=1 Spiljar, M. Steinbach, K. Rigo, D. Suarez-Zamorano, N. Wagner, I. Hadadi, N. Vincenti, I. Page, N. Klimek, B. Rochat, M.-A. Kreutzfeldt, M. Chevalier, C. Stojanovic, O. Mack, M. Cansever, D. Greter, M. Merkler, D. Trajkovski, M. 2020-08-30 doi:10.1101/2020.08.28.269563 Cold Spring Harbor Laboratory Press 2020-08-30 <![CDATA[ Morphological plasticity in Chlamydomonas reinhardtii and acclimation to micropollutant stress ]]> https://biorxiv.org/content/10.1101/2020.08.29.273557v1?rss=1 Cheloni, G. Slaveykova, V. I. 2020-08-31 doi:10.1101/2020.08.29.273557 Cold Spring Harbor Laboratory Press 2020-08-31 <![CDATA[ Two distinct phases of chloroplast biogenesis during de-etiolation in Arabidopsis thaliana ]]> https://biorxiv.org/content/10.1101/2020.08.30.274043v1?rss=1 Pipitone, R. Eicke, S. Pfister, B. Glauser, G. Falconet, D. Uwizeye, C. Pralon, T. Zeeman, S. Kessler, F. Demarsy, E. 2020-08-31 doi:10.1101/2020.08.30.274043 Cold Spring Harbor Laboratory Press 2020-08-31 <![CDATA[ Simulating the outcome of amyloid treatments in Alzheimer's Disease from multi-modal imaging and clinical data ]]> https://biorxiv.org/content/10.1101/2020.09.02.279521v1?rss=1 Abi Nader, C. Ayache, N. Frisoni, G. B. Robert, P. Lorenzi, M. 2020-09-03 doi:10.1101/2020.09.02.279521 Cold Spring Harbor Laboratory Press 2020-09-03 <![CDATA[ A single nuclei transcriptomic analysis of the Atlantic salmon gill through smoltification and seawater transfer ]]> https://biorxiv.org/content/10.1101/2020.09.03.281337v1?rss=1 West, A. C. Mizoro, Y. Wood, S. H. Ince, L. Iversen, M. Jorgensen, E. H. Nome, T. Sandve, S. R. Loudon, A. S. I. Hazlerigg, D. G. 2020-09-03 doi:10.1101/2020.09.03.281337 Cold Spring Harbor Laboratory Press 2020-09-03 <![CDATA[ From scales to armour: scale losses and trunk bony plate gains in ray-finned fishes ]]> https://biorxiv.org/content/10.1101/2020.09.09.288886v1?rss=1 11,000 species, and by using stochastic mapping and Bayesian methods, we inferred scale loss events and trunk bony plate acquisitions. Our results reveal that a scaled tegument is the most frequent state in actinopterygians, but multiple independent scale loss events occurred along their phylogeny with essentially no scale re-acquisition. Based on linear mixed models, we found evidence supporting that after a scale loss event, fishes tend to change their ecology and adopt a benthic lifestyle. Furthermore, we show that trunk bony plates appeared independently multiple times along the phylogeny. By using fitted likelihood models for character evolution, we show that trunk bony plate acquisitions were dependent over a previous scale loss event. Overall, our findings support the hypothesis that tegument cover is a key evolutionary trait underlying actinopterygian radiation. Impact SummaryRay-finned fishes (actinopterygians) are the most diverse vertebrate group in the world. The majority of these fishes possess scales as a protective shield covering their trunk. However, several lineages display a body armour composed of trunk bony plates or are devoid of any protective structures. The diversity and the transitions between different tegument coverage types have not been previously studied in an evolutionary framework. Here, we investigate which structure was present at the origin of ray-finned fishes and how the different phenotypes emerged through time. We show that a scaled tegument was the most widespread sate along ray-finned fish evolution, yet scale losses occurred multiple independent times, while acquiring scales again almost never happened. Moreover, we reveal that scaleless teguments most probably led species to change their ecology and colonise the floors of oceans and water bodies. The functional advantages of a scaleless tegument in a benthic environment are yet to be demonstrated, but the increased cutaneous respiration could be an explanation. We show that trunk bony plates also emerged independently multiple times along the evolution of ray-finned fishes but these armours protecting the trunk can only appear after a scale loss event. Therefore, while the acquisitions of trunk bony plates are phylogenetically independent, they need a "common ground" to emerge. All together, our findings provide evidence that the various tegument covers have contributed to the outstanding diversification of ray-finned fishes. ]]> Lemopoulos, A. Montoya-Burgos, J. I. 2020-09-09 doi:10.1101/2020.09.09.288886 Cold Spring Harbor Laboratory Press 2020-09-09 <![CDATA[ Unraveling the Developmental Dynamic of Visual Exploration of Social Interactions in Autism ]]> https://biorxiv.org/content/10.1101/2020.09.14.290106v1?rss=1 Kojovic, N. Franchini, M. Sandini, C. Sperdin, H. F. Jan, R. K. Zoeller, D. Schaer, M. 2020-09-17 doi:10.1101/2020.09.14.290106 Cold Spring Harbor Laboratory Press 2020-09-17 <![CDATA[ Rhythmic expression of Neurofibromin 1 in mushroom body neurons mediates circadian wake drive through activating cAMP-PKA signaling ]]> https://biorxiv.org/content/10.1101/2020.09.16.299859v1?rss=1 Almeida, P. M. Solis, B. L. Feidler, A. Nagoshi, E. 2020-09-16 doi:10.1101/2020.09.16.299859 Cold Spring Harbor Laboratory Press 2020-09-16 <![CDATA[ Multilocus phylogeny and historical biogeography of Hypostomus shed light on the processes of fish diversification in La Plata Basin ]]> https://biorxiv.org/content/10.1101/2020.09.22.308064v1?rss=1 Cardoso, Y. P. de Queiroz, L. Montoya-Burgos, J. Bahechar, I. Posadas, P. 2020-09-23 doi:10.1101/2020.09.22.308064 Cold Spring Harbor Laboratory Press 2020-09-23 <![CDATA[ Dorsal to ventral imbalance in the superior longitudinal fasciculus mediates methylphenidate's effect on beta oscillations in ADHD ]]> https://biorxiv.org/content/10.1101/2020.09.23.309526v1?rss=1 Mazzetti, C. Gonzales Damatac, C. Sprooten, E. ter Huurne, N. Buitelaar, J. K. Jensen, O. 2020-09-23 doi:10.1101/2020.09.23.309526 Cold Spring Harbor Laboratory Press 2020-09-23 <![CDATA[ Phosphorylated paxillin and FAK constitute subregions within focal adhesions ]]> https://biorxiv.org/content/10.1101/2020.09.24.311126v1?rss=1 Bachmann, M. Skripka, A. Wehrle-Haller, B. M. Bastmeyer, M. 2020-09-25 doi:10.1101/2020.09.24.311126 Cold Spring Harbor Laboratory Press 2020-09-25 <![CDATA[ Early alterations of large-scale brain networkstemporal dynamics in young children with autism. ]]> https://biorxiv.org/content/10.1101/2020.09.24.311423v1?rss=1 Bochet, A. Sperdin, H. F. Rihs, T. A. Kojovic, N. Franchini, M. Jan, R. K. Michel, C. M. Schaer, M. 2020-09-24 doi:10.1101/2020.09.24.311423 Cold Spring Harbor Laboratory Press 2020-09-24 <![CDATA[ An early cortical progenitor-specific mechanism regulates thalamocortical innervation ]]> https://biorxiv.org/content/10.1101/2020.09.25.312785v1?rss=1 Pal, S. Dwivedi, D. Pramanik, T. Godbole, G. Iwasato, T. Jabaudon, D. Bhalla, U. S. Tole, S. 2020-09-25 doi:10.1101/2020.09.25.312785 Cold Spring Harbor Laboratory Press 2020-09-25 <![CDATA[ How motivational signals disrupt metacognitive signals in the human VMPFC. ]]> https://biorxiv.org/content/10.1101/2020.10.02.323550v1?rss=1 Hoven, M. Brunner, G. de Boer, N. S. Goudriaan, A. E. Denys, D. van Holst, R. J. Luigjes, J. Lebreton, M. 2020-10-05 doi:10.1101/2020.10.02.323550 Cold Spring Harbor Laboratory Press 2020-10-05 <![CDATA[ Trans-generational inheritance of centromere identity requires the CENP-A N-terminal tail in the C. elegans maternal germ line ]]> https://biorxiv.org/content/10.1101/2020.10.05.325985v1?rss=1 Prosee, R. Wenda, J. Gabus, C. Delaney, K. Schwager, F. Gotta, M. Steiner, F. 2020-10-05 doi:10.1101/2020.10.05.325985 Cold Spring Harbor Laboratory Press 2020-10-05 <![CDATA[ Dominant monoallelic variant in the PAK2 gene causes Knobloch syndrome type 2 ]]> https://biorxiv.org/content/10.1101/2020.10.06.328419v1?rss=1 Antonarakis, S. E. Holoubek, A. Rapti, M. Rademaker, J. Meylan, J. Iwaszkiewicz, J. Zoete, V. Ansar, M. BOREL, C. c. Menzel, O. Kuzelova, K. Santoni, F. A. 2020-10-07 doi:10.1101/2020.10.06.328419 Cold Spring Harbor Laboratory Press 2020-10-07 <![CDATA[ Schengen-pathway controls spatially separated and chemically distinct lignin deposition in the endodermis. ]]> https://biorxiv.org/content/10.1101/2020.10.07.329664v1?rss=1 Reyt, G. Ramakrishna, P. Salas-Gonzalez, I. Fujita, S. Love, A. Tiemessen, D. Lapierre, C. Morreel, K. Calvo Polanco, M. Flis, P. Geldner, N. Boursiac, Y. Boerjan, W. George, M. W. Castrillo, G. Salt, D. E. 2020-10-08 doi:10.1101/2020.10.07.329664 Cold Spring Harbor Laboratory Press 2020-10-08 <![CDATA[ Education and income show heterogeneous relationships to lifespan brain and cognitive differences across European and US cohorts ]]> https://biorxiv.org/content/10.1101/2020.10.12.335687v1?rss=1 Walhovd, K. B. Fjell, A. Wang, Y. Amlien, I. K. Mowinckel, A. M. Lindenberger, U. Duezel, S. Bartres-Faz, D. Ebmeier, K. Drevon, C. A. Barre, W. Ghisletta, P. Johansen, L. B. Kievit, R. A. Henson, R. N. Madsen, K. S. Nyberg, L. Harris, J. R. Sole-Padulles, C. Pudas, S. Sorensen, O. Westerhausen, R. Zsoldos, E. Nawijn, L. Lyngstad, T. H. Suri, S. Penninx, B. Rogeberg, O. J. Brandmaier, A. 2020-10-14 doi:10.1101/2020.10.12.335687 Cold Spring Harbor Laboratory Press 2020-10-14 <![CDATA[ The claustrum-medial prefrontal cortex network controls attentional set-shifting ]]> https://biorxiv.org/content/10.1101/2020.10.14.339259v1?rss=1 Fodoulian, L. Gschwend, O. Huber, C. Mutel, S. Salazar, R. Leone, R. Renfer, J.-R. Ekundayo, K. Rodriguez, I. Carleton, A. 2020-10-15 doi:10.1101/2020.10.14.339259 Cold Spring Harbor Laboratory Press 2020-10-15 <![CDATA[ Beyond broadband: towards a spectral decomposition of EEG microstates ]]> https://biorxiv.org/content/10.1101/2020.10.16.342378v1?rss=1 Ferat, V. Seeber, M. Michel, C. M. Ros, T. 2020-10-16 doi:10.1101/2020.10.16.342378 Cold Spring Harbor Laboratory Press 2020-10-16 <![CDATA[ Physical activity and general cognitive functioning: A Mendelian Randomization study ]]> https://biorxiv.org/content/10.1101/2020.10.16.342675v1?rss=1 Cheval, B. Darrous, L. Choi, K. Klimentidis, Y. Raichlen, D. Alexander, G. Cullati, S. Kutalik, Z. Boisgontier, M. P. 2020-10-16 doi:10.1101/2020.10.16.342675 Cold Spring Harbor Laboratory Press 2020-10-16 <![CDATA[ Mice alternate between discrete strategies during perceptual decision-making ]]> https://biorxiv.org/content/10.1101/2020.10.19.346353v1?rss=1 Ashwood, Z. C. Roy, N. A. Stone, I. R. International Brain Laboratory, T. Churchland, A. K. Pouget, A. Pillow, J. W. 2020-10-21 doi:10.1101/2020.10.19.346353 Cold Spring Harbor Laboratory Press 2020-10-21 <![CDATA[ Low-frequency subthalamic neural oscillations are involved in explicit and implicit facial emotional processing - a local field potential study ]]> https://biorxiv.org/content/10.1101/2020.10.21.348755v1?rss=1 Dondaine, T. Duprez, J. Houvenaghel, J.-F. Modolo, J. Haegelen, C. Robert, G. Millet, B. Drapier, D. Verin, M. Sauleau, P. 2020-10-22 doi:10.1101/2020.10.21.348755 Cold Spring Harbor Laboratory Press 2020-10-22 <![CDATA[ Roughness and dynamics of proliferating cell fronts as a probe of cell-cell interactions ]]> https://biorxiv.org/content/10.1101/2020.10.26.354878v1?rss=1 Rapin, G. Caballero, N. Gaponenko, I. Ziegler, B. Rawleight, A. Moriggi, E. Giamarchi, T. Brown, S. A. Paruch, P. 2020-10-26 doi:10.1101/2020.10.26.354878 Cold Spring Harbor Laboratory Press 2020-10-26 <![CDATA[ Human temporal voice areas are sensitive to chimpanzee vocalizations ]]> https://biorxiv.org/content/10.1101/2020.10.29.360362v1?rss=1 Ceravolo, L. Debracque, C. Gruber, T. Grandjean, D. 2020-10-29 doi:10.1101/2020.10.29.360362 Cold Spring Harbor Laboratory Press 2020-10-29 <![CDATA[ Analysis Of Polycerate Mutants Reveals The Evolutionary Co-Option Of HOXD1 To Determine The Number And Topology Of Horns In Bovidae ]]> https://biorxiv.org/content/10.1101/2020.11.04.363069v1?rss=1 Allais-Bonnet, A. Hintermann, A. Deloche, M.-C. Cornette, R. Bardou, P. Naval-Sanchez, M. Pinton, A. Haruda, A. Grohs, C. Zakany, J. Bigi, D. Medugorac, I. Putelat, O. Greyvenstein, O. Hadfield, T. Ben Jemaa, S. Bunevski, G. Menzi, F. Hirter, N. Paris, J. M. Hedges, J. Palhiere, I. Rupp, R. Lenstra, J. A. Gidney, L. Lesur, J. Schafberg, R. Stache, M. Wandhammer, M.-D. Arbogast, R.-M. Guintard, C. Blin, A. Boukadiri, A. Riviere, J. Esquerre, D. Donnadieu, C. Danchin-Burge, C. Reich, C. M. Riley, D. van Marle-Koster, E. Cockett, N. Hayes, B. J. A. Droege 2020-11-04 doi:10.1101/2020.11.04.363069 Cold Spring Harbor Laboratory Press 2020-11-04 <![CDATA[ HOX13-MEDIATED DBX2 REGULATION IN LIMBS SUGGESTS INTER-TAD SHARING OF ENHANCERS ]]> https://biorxiv.org/content/10.1101/2020.11.16.379412v1?rss=1 Beccari, L. Jaquier, G. Lopez-Delisle, L. Rodriguez-Carballo, E. Mascrez, B. Gitto, S. Woltering, J. Duboule, D. 2020-11-17 doi:10.1101/2020.11.16.379412 Cold Spring Harbor Laboratory Press 2020-11-17 <![CDATA[ A gene desert required for regulatory control of pleiotropic Shox2 expression and embryonic survival ]]> https://biorxiv.org/content/10.1101/2020.11.22.393173v1?rss=1 Abassah-Oppong, S. Mannion, B. Tissieres, V. Rodriguez-Carballo, E. Ljubojevic, A. Darbellay, F. Festa, T. A. Sullivan, C. S. Kelman, G. Hunter, R. D. Novak, C. S. Plajzer-Frick, I. Tran, S. Akiyama, J. A. Barozzi, I. Andrey, G. Lopez-Rios, J. Dickel, D. E. Visel, A. Pennacchio, L. A. Cobb, J. Osterwalder, M. 2020-11-22 doi:10.1101/2020.11.22.393173 Cold Spring Harbor Laboratory Press 2020-11-22 <![CDATA[ A Nasal Spray Solution of Grapefruit Seed Extract plus Xylitol Displays Virucidal Activity Against SARS-Cov-2 In Vitro ]]> https://biorxiv.org/content/10.1101/2020.11.23.394114v1?rss=1 3 log10 CCID50 infectious virus from, 3.67 log10 CCID50/0.1 mL to an undetectable amount of infectious virus. The present results validated by two independent sets of experiments, performed by different labs, on different viral strains, provide early evidence to encourage further pilot and clinical studies aimed at investigating the use of Xlear as a potential treatment for COVID-19 ]]> Ferrer, G. A. Betancour, A. Go, C. C. Vazquez, H. Westover, J. B. Cagno, V. Tapparel, C. Sanchez-Gonzalez, M. A. 2020-11-25 doi:10.1101/2020.11.23.394114 Cold Spring Harbor Laboratory Press 2020-11-25 <![CDATA[ Establishment of a highly efficient gene disruption strategy to analyze and manipulate lipid co-regulatory networks ]]> https://biorxiv.org/content/10.1101/2020.11.24.395632v1?rss=1 Harayama, T. Hashidate-Yoshida, T. Aguilera-Romero, A. Hamano, F. Morimoto, R. Shimizu, T. Riezman, H. 2020-11-24 doi:10.1101/2020.11.24.395632 Cold Spring Harbor Laboratory Press 2020-11-24 <![CDATA[ Transient active osmotic swelling of epithelium upon curvature induction ]]> https://biorxiv.org/content/10.1101/2020.11.25.398107v1?rss=1 Tomba, C. Luchnikov, V. Barberi, L. Blanch-Mercader, C. Roux, A. 2020-11-26 doi:10.1101/2020.11.25.398107 Cold Spring Harbor Laboratory Press 2020-11-26 <![CDATA[ Frontoparietal, cerebellum network codes for accurate intention prediction in altered perceptual conditions ]]> https://biorxiv.org/content/10.1101/2020.11.26.399782v1?rss=1 Ceravolo, L. Schaerlaeken, S. Fruehholz, S. Glowinski, D. Grandjean, D. 2020-11-26 doi:10.1101/2020.11.26.399782 Cold Spring Harbor Laboratory Press 2020-11-26 <![CDATA[ Basal ganglia and cerebellar contributions to vocal emotion processing: a high resolution fMRI study ]]> https://biorxiv.org/content/10.1101/2020.11.26.399790v1?rss=1 Ceravolo, L. Fruehholz, S. Pierce, J. Grandjean, D. Peron, J. 2020-11-26 doi:10.1101/2020.11.26.399790 Cold Spring Harbor Laboratory Press 2020-11-26 <![CDATA[ Structural basis of the activation of the CC chemokine receptor 5 by a chemokine agonist ]]> https://biorxiv.org/content/10.1101/2020.11.27.401117v1?rss=1 Isaikina, P. Tsai, C.-J. Dietz, N. B. Pamula, F. Grahl, A. Goldie, K. N. Guixa-Gonzalez, R. Schertler, G. F. X. Hartley, O. Stahlberg, H. Maier, T. Deupi, X. Grzesiek, S. 2020-11-27 doi:10.1101/2020.11.27.401117 Cold Spring Harbor Laboratory Press 2020-11-27 <![CDATA[ Suppressing the morning cortisol rise after memory reactivation at 4 a.m. enhances episodic memory reconsolidation in humans ]]> https://biorxiv.org/content/10.1101/2020.11.30.404707v1?rss=1 Antypa, D. Perrault, A. A. Vuilleumier, P. Schwartz, S. Rimmele, U. 2020-12-02 doi:10.1101/2020.11.30.404707 Cold Spring Harbor Laboratory Press 2020-12-02 <![CDATA[ Deep immune profiling reveals targetable mechanisms of immune evasion in checkpoint blockade-refractory glioblastoma ]]> https://biorxiv.org/content/10.1101/2020.12.01.404939v1?rss=1 View larger version (39K): org.highwire.dtl.DTLVardef@bdd0e4org.highwire.dtl.DTLVardef@1dd335forg.highwire.dtl.DTLVardef@157bfa6org.highwire.dtl.DTLVardef@1e76151_HPS_FORMAT_FIGEXP M_FIG C_FIG In BriefIn mice and humans, tumors that were sensitive to checkpoint blockade had consistent immunological features. A mouse model of glioma that is refractory to checkpoint blockade was sensitized by increasing antigen presentation through a variety of approaches. ]]> Simonds, E. F. Lu, E. D. Liu, E. V. Tamaki, W. Rancan, C. Stultz, J. Sinha, M. McHenry, L. K. Nasholm, N. M. Chuntova, P. Sundstrom, A. Genoud, V. Shahani, S. A. Wang, L. D. brown, c. Walker, P. R. Swartling, F. J. Fong, L. Okada, H. Weiss, W. A. Hellstrom, M. 2020-12-02 doi:10.1101/2020.12.01.404939 Cold Spring Harbor Laboratory Press 2020-12-02 <![CDATA[ Common computational principle for vibro-tactile pitch perception in mouse and human ]]> https://biorxiv.org/content/10.1101/2020.12.02.406272v1?rss=1 Prsa, M. Kilicel, D. Nourizonoz, A. Lee, K.-S. Huber, D. 2020-12-03 doi:10.1101/2020.12.02.406272 Cold Spring Harbor Laboratory Press 2020-12-03 <![CDATA[ Identification of low micromolar SARS-CoV-2 Mpro inhibitors from hits identified by in silico screens ]]> https://biorxiv.org/content/10.1101/2020.12.03.409441v1?rss=1 Rossetti, G. G. Ossorio, M. Barriot, S. Tropia, L. Dionellis, V. S. Gorgulla, C. Arthanari, H. Mohr, P. Gamboni, R. Halazonetis, T. D. 2020-12-03 doi:10.1101/2020.12.03.409441 Cold Spring Harbor Laboratory Press 2020-12-03 <![CDATA[ A sinusoidal transform of the visual field in cortical area V2 ]]> https://biorxiv.org/content/10.1101/2020.12.08.416651v1?rss=1 Sedigh-Sarvestani, M. Lee, K.-S. Satterfield, R. Shultz, N. Fitzpatrick, D. 2020-12-09 doi:10.1101/2020.12.08.416651 Cold Spring Harbor Laboratory Press 2020-12-09 <![CDATA[ The molecular basis, genetic control and pleiotropic effects of local gene co-expression ]]> https://biorxiv.org/content/10.1101/2020.12.11.421396v1?rss=1 Ribeiro, D. M. Rubinacci, S. Ramisch, A. Hofmeister, R. J. Dermitzakis, E. T. Delaneau, O. 2020-12-12 doi:10.1101/2020.12.11.421396 Cold Spring Harbor Laboratory Press 2020-12-12 <![CDATA[ Paradoxical neuronal hyperexcitability in a mouse model of mitochondrial pyruvate import deficiency ]]> https://biorxiv.org/content/10.1101/2020.12.22.423903v1?rss=1 De La Rossa, A. Laporte, M. H. Astori, S. Marissal, T. Montessuit, S. Sheshadri, P. Ramos-Fernández, E. Mendez, P. Khani, A. Quairiaux, C. Taylor, E. Rutter, J. Nunes, J. M. carleton, a. Duchen, M. Sandi, C. Martinou, J.-C. 2020-12-22 doi:10.1101/2020.12.22.423903 Cold Spring Harbor Laboratory Press 2020-12-22 <![CDATA[ Receptor-linked environment-sensitive probe monitors the local membrane environment surrounding the insulin receptor ]]> https://biorxiv.org/content/10.1101/2020.12.23.424145v1?rss=1 Umebayashi, M. Takemoto, S. Reymond, L. Sundukova, M. Hovius, R. Bucci, A. Heppenstall, P. A. Yokota, H. Johnsson, K. Riezman, H. 2020-12-23 doi:10.1101/2020.12.23.424145 Cold Spring Harbor Laboratory Press 2020-12-23 <![CDATA[ An in vivo CRISPR screening platform for prioritizing therapeutic targets in AML ]]> https://biorxiv.org/content/10.1101/2020.12.28.424340v1?rss=1 Lin, S. Larrue, C. Seong, B. K. A. Dharia, N. V. Kuljanin, M. Wechsler, C. Kugener, G. Robichaud, A. Conway, A. Mashaka, T. N. Mouche, S. Adane, B. Ryan, J. Mancias, J. D. Younger, S. T. Piccioni, F. Lee, L. Wunderlich, M. Letai, A. Tamburini, J. Stegmaier, K. 2020-12-28 doi:10.1101/2020.12.28.424340 Cold Spring Harbor Laboratory Press 2020-12-28 <![CDATA[ Allosteric communication in Class A β-lactamases occurs via Cooperative Coupling of Loop Dynamics ]]> https://biorxiv.org/content/10.1101/2020.12.30.424904v1?rss=1 Galdadas, I. Qu, S. Oliveira, A. S. F. Olehnovics, E. Mack, A. R. Mojica, M. F. Agarwal, P. K. Tooke, C. L. Gervasio, F. L. Spencer, J. Bonomo, R. A. Mulholland, A. J. Haider, S. 2021-01-01 doi:10.1101/2020.12.30.424904 Cold Spring Harbor Laboratory Press 2021-01-01 <![CDATA[ Spatiotemporal dynamics of human attention revealed byintracerebral recording ]]> https://biorxiv.org/content/10.1101/2021.01.02.425103v1?rss=1 Seidel Malkinson, T. Bayle, D. J. Bourgeois, A. Lehongre, K. Fernandez, S. Navarro, V. Adam, C. Margulies, D. Sitt, J. D. Bartolomeo, P. 2021-01-04 doi:10.1101/2021.01.02.425103 Cold Spring Harbor Laboratory Press 2021-01-04 <![CDATA[ Synchronous brain dynamics establish brief states of communality in distant neuronal populations ]]> https://biorxiv.org/content/10.1101/2021.01.07.425731v1?rss=1 Seeber, M. Michel, C. M. 2021-01-08 doi:10.1101/2021.01.07.425731 Cold Spring Harbor Laboratory Press 2021-01-08 <![CDATA[ Protein Phosphatase 1 regulates atypical chromosome segregation and cell polarity during mitotic and meiotic division in Plasmodium sexual stages ]]> https://biorxiv.org/content/10.1101/2021.01.15.426883v1?rss=1 Zeeshan, M. Pandey, R. SUBUDHI, A. K. Ferguson, D. J. P. Kaur, G. Rashpa, R. Nugmanova, R. Brady, D. Bottrill, A. vaughan, s. Brochet, M. Bollen, M. Pain, A. Holder, A. A. Guttery, D. S. Tewari, R. 2021-01-17 doi:10.1101/2021.01.15.426883 Cold Spring Harbor Laboratory Press 2021-01-17 <![CDATA[ eIF4E3 Forms an Active eIF4F Complex during Stresses (eIF4FS) Targeting mTOR and Re-Programs the Translatome. ]]> https://biorxiv.org/content/10.1101/2021.01.22.427788v1?rss=1 Weiss, B. Allen, G. E. Kloehn, J. A. Abid, K. Jaquier-Gubler, P. Curran, J. A. 2021-01-23 doi:10.1101/2021.01.22.427788 Cold Spring Harbor Laboratory Press 2021-01-23 <![CDATA[ Quantitative coupling of cell volume and membrane tension during osmotic shocks ]]> https://biorxiv.org/content/10.1101/2021.01.22.427801v1?rss=1 Roffay, C. Molinard, G. Kim, K. Barbarassa, V. Urbanska, M. Mercier, V. Garcia Calvo, J. Matile, S. Guck, J. Lenz, M. Roux, A. 2021-01-23 doi:10.1101/2021.01.22.427801 Cold Spring Harbor Laboratory Press 2021-01-23 <![CDATA[ Imagined speech can be decoded from low- and cross-frequency features in perceptual space ]]> https://biorxiv.org/content/10.1101/2021.01.26.428315v1?rss=1 Proix, T. Delgado Saa, J. Christen, A. Martin, S. Pasley, B. N. Knight, R. T. Tian, X. Poeppel, D. Doyle, W. K. Devinsky, O. Arnal, L. H. Megevand, P. Giraud, A.-L. 2021-01-26 doi:10.1101/2021.01.26.428315 Cold Spring Harbor Laboratory Press 2021-01-26 <![CDATA[ Suberin plasticity to developmental and exogenous cues is regulated by a set of MYB transcription factors ]]> https://biorxiv.org/content/10.1101/2021.01.27.428267v1?rss=1 Shukla, V. Han, J.-P. Cléard, F. Legendre-Lefebvre, L. Gully, K. Flis, P. Berhin, A. Andersen, T. G. Salt, D. E. Nawrath, C. Barberon, M. 2021-01-27 doi:10.1101/2021.01.27.428267 Cold Spring Harbor Laboratory Press 2021-01-27 <![CDATA[ Dynamic dichotomy of accumbal population activity underlies cocaine sensitization ]]> https://biorxiv.org/content/10.1101/2021.01.28.428587v1?rss=1 van Zessen, R. Flakowski, J. Lüscher, C. 2021-01-30 doi:10.1101/2021.01.28.428587 Cold Spring Harbor Laboratory Press 2021-01-30 <![CDATA[ The DEAD-box RNA helicases RhlE2 is a global regulator of Pseudomonas aeruginosa lifestyle and pathogenesis ]]> https://biorxiv.org/content/10.1101/2021.01.29.428592v1?rss=1 Valentini, M. Hausmann, S. Gonzalez, D. Geiser, J. 2021-01-29 doi:10.1101/2021.01.29.428592 Cold Spring Harbor Laboratory Press 2021-01-29 <![CDATA[ Single-cell sequencing reveals clonally expanded plasma cells during chronic viral infection produce virus-specific and cross-reactive antibodies ]]> https://biorxiv.org/content/10.1101/2021.01.29.428852v1?rss=1 View larger version (22K): org.highwire.dtl.DTLVardef@9d0852org.highwire.dtl.DTLVardef@18d46fcorg.highwire.dtl.DTLVardef@2f7f80org.highwire.dtl.DTLVardef@5be3fd_HPS_FORMAT_FIGEXP M_FIG Graphical abstract.Single-cell sequencing reveals clonally expanded plasma cells during chronic viral infection produce virus-specific and cross-reactive antibodies. C_FIG ]]> Neumeier, D. Pedrioli, A. Genovese, A. Sandu, I. Ehling, R. Hong, K.-L. Papadopoulou, C. Agrafiotis, A. Kuhn, R. Robbiani, D. Han, J. Hauri, L. Csepregi, L. Greiff, V. Merkler, D. Reddy, S. T. Oxenius, A. Yermanos, A. 2021-01-31 doi:10.1101/2021.01.29.428852 Cold Spring Harbor Laboratory Press 2021-01-31 <![CDATA[ PalaCell2D: A framework for detailed tissue morphogenesis ]]> https://biorxiv.org/content/10.1101/2021.01.30.428940v1?rss=1 Conradin, R. Coreixas, C. Latt, J. Chopard, B. 2021-02-01 doi:10.1101/2021.01.30.428940 Cold Spring Harbor Laboratory Press 2021-02-01 <![CDATA[ MESOMELIC DYSPLASIAS ASSOCIATED WITH THE HOXD LOCUS ARE CAUSED BY REGULATORY REALLOCATIONS ]]> https://biorxiv.org/content/10.1101/2021.02.01.429171v1?rss=1 Bolt, C. C. Lopez-Delisle, L. Mascrez, B. Duboule, D. 2021-02-02 doi:10.1101/2021.02.01.429171 Cold Spring Harbor Laboratory Press 2021-02-02 <![CDATA[ Extracellular membrane tubules involved in suberin deposition in plant cell walls ]]> https://biorxiv.org/content/10.1101/2021.02.02.429332v1?rss=1 De Bellis, D. Kalmbach, L. Marhavy, P. Daraspe, J. Geldner, N. Barberon, M. 2021-02-03 doi:10.1101/2021.02.02.429332 Cold Spring Harbor Laboratory Press 2021-02-03 <![CDATA[ Connection Failure: Differences in White Matter Microstructure are associated with 5-HTTLPR but not with Risk-Seeking for Losses ]]> https://biorxiv.org/content/10.1101/2021.02.03.429606v1?rss=1 Neukam, P. T. Mueller, D. K. Deza-Araujo, Y. I. Pooseh, S. Witt, S. H. Rietschel, M. Smolka, M. N. 2021-02-05 doi:10.1101/2021.02.03.429606 Cold Spring Harbor Laboratory Press 2021-02-05 <![CDATA[ Crystal structure of a bacterial CNNM magnesium transporter ]]> https://biorxiv.org/content/10.1101/2021.02.11.430706v1?rss=1 Chen, Y. S. Kozlov, G. Armitano, J. Moeller, B. J. Fakih, R. Rohaim, A. Roux, B. Burke, J. E. Gehring, K. 2021-02-11 doi:10.1101/2021.02.11.430706 Cold Spring Harbor Laboratory Press 2021-02-11 <![CDATA[ CONTEXT-INDEPENDENT FUNCTION OF A CHROMATIN BOUNDARY IN VIVO ]]> https://biorxiv.org/content/10.1101/2021.02.11.430727v1?rss=1 Willemin, A. Lopez-Delisle, L. Bolt, C. C. Gadolini, M.-L. Duboule, D. Rodriguez-Carballo, E. 2021-02-11 doi:10.1101/2021.02.11.430727 Cold Spring Harbor Laboratory Press 2021-02-11 <![CDATA[ Dlc1 controls cardio-vascular development downstream of Vegfa/Kdrl/Nrp1 signaling in the zebrafish embryo. ]]> https://biorxiv.org/content/10.1101/2021.02.11.430763v1?rss=1 LINNERZ, T. BERTRAND, J. Y. 2021-02-11 doi:10.1101/2021.02.11.430763 Cold Spring Harbor Laboratory Press 2021-02-11 <![CDATA[ Exploring MEG brain fingerprints: evaluation, pitfalls and interpretations ]]> https://biorxiv.org/content/10.1101/2021.02.15.431253v1?rss=1 Sareen, E. Zahar, S. Van De Ville, D. Gupta, A. Griffa, A. Amico, E. 2021-02-16 doi:10.1101/2021.02.15.431253 Cold Spring Harbor Laboratory Press 2021-02-16 <![CDATA[ A mixture of generative models strategy helps humans generalize across tasks ]]> https://biorxiv.org/content/10.1101/2021.02.16.431506v1?rss=1 HERCE CASTANON, S. Cardoso-Leite, P. Green, C. S. Altarelli, I. Schrater, P. Bavelier, D. 2021-02-16 doi:10.1101/2021.02.16.431506 Cold Spring Harbor Laboratory Press 2021-02-16 <![CDATA[ ChEC-seq: a robust method to identify protein-DNA interactions genome-wide ]]> https://biorxiv.org/content/10.1101/2021.02.18.431798v1?rss=1 Bruzzone, M. J. Albert, B. Hafner, L. Kubik, S. Lezaja, A. Mattarocci, S. Shore, D. M. 2021-02-18 doi:10.1101/2021.02.18.431798 Cold Spring Harbor Laboratory Press 2021-02-18 <![CDATA[ Constructing and validating a transferable epidemic risk index in data scarce environments using open data: a case study for dengue in the Philippines ]]> https://biorxiv.org/content/10.1101/2021.02.23.432447v1?rss=1 Hierink, F. Margutti, J. van den Homberg, M. Ray, N. 2021-02-23 doi:10.1101/2021.02.23.432447 Cold Spring Harbor Laboratory Press 2021-02-23 <![CDATA[ Progranulin promotes immune evasion of pancreatic adenocarcinoma through regulation of MHCI expression ]]> https://biorxiv.org/content/10.1101/2021.02.24.432700v1?rss=1 Cheung, P. F. Yang, J. Krengel, K. Althoff, K. Yip, C. Siu, E. H. Ng, L. W. Lang, K. S. Cham, L. Engel, D. R. Soun, C. Cima, I. Scheffler, B. Striefler, J. K. Sinn, M. Bahra, M. Pelzer, U. Oettle, H. Markus, P. Smeets, E. M. Aarntzen, E. H. Savvatakis, K. Liffers, S.-T. Neander, C. Bazarna, A. Zhang, X. Paschen, A. Crawford, H. C. Chan, A. W. Cheung, S. T. Siveke, J. T. 2021-02-25 doi:10.1101/2021.02.24.432700 Cold Spring Harbor Laboratory Press 2021-02-25 <![CDATA[ Open Natural Products Research: Curation and Dissemination of Biological Occurrences of Chemical Structures through Wikidata ]]> https://biorxiv.org/content/10.1101/2021.02.28.433265v1?rss=1 View larger version (14K): org.highwire.dtl.DTLVardef@184136borg.highwire.dtl.DTLVardef@16e0d6org.highwire.dtl.DTLVardef@30ae1org.highwire.dtl.DTLVardef@1bf4825_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Rutz, A. Sorokina, M. Galgonek, J. Mietchen, D. Willighagen, E. Graham, J. G. Stephan, R. Page, R. Vondrasek, J. Steinbeck, C. Pauli, G. Wolfender, J.-L. Bisson, J. Allard, P.-M. 2021-03-01 doi:10.1101/2021.02.28.433265 Cold Spring Harbor Laboratory Press 2021-03-01 <![CDATA[ Cell-specific alterations in Pitx1 regulatory landscape activation caused by the loss of a single enhancer ]]> https://biorxiv.org/content/10.1101/2021.03.10.434611v1?rss=1 Rouco, R. Bompadre, O. Rauseo, A. Fazio, O. Thorel, F. Peraldi, R. Andrey, G. 2021-03-10 doi:10.1101/2021.03.10.434611 Cold Spring Harbor Laboratory Press 2021-03-10 <![CDATA[ Distinct profiles of spatio-temporal brain dynamics along symptoms dimensions in autism ]]> https://biorxiv.org/content/10.1101/2021.03.11.434353v1?rss=1 Mullier, E. Kojovic, N. Denervaud, S. Vohryzek, J. Hagmann, P. Schaer, M. 2021-03-11 doi:10.1101/2021.03.11.434353 Cold Spring Harbor Laboratory Press 2021-03-11 <![CDATA[ Information flows from hippocampus to cortex during replay of verbal working memory items. ]]> https://biorxiv.org/content/10.1101/2021.03.11.434989v1?rss=1 Dimakopoulos, V. S. Stieglitz, L. Megevand, P. Sarnthein, J. 2021-03-11 doi:10.1101/2021.03.11.434989 Cold Spring Harbor Laboratory Press 2021-03-11 <![CDATA[ Paper-and-pencil questionnaires analysis: a new automated technique to reduce analysis time and errors. ]]> https://biorxiv.org/content/10.1101/2021.03.12.435109v1?rss=1 Chabert, C. Collado, A. Cheval, B. Hue, O. 2021-03-12 doi:10.1101/2021.03.12.435109 Cold Spring Harbor Laboratory Press 2021-03-12 <![CDATA[ Amplitude and phase coupling optimize information transfer between brain networks that function at criticality ]]> https://biorxiv.org/content/10.1101/2021.03.15.435461v1?rss=1 Avramiea, A.-E. Masood, A. Mansvelder, H. D. Linkenkaer-Hansen, K. 2021-03-15 doi:10.1101/2021.03.15.435461 Cold Spring Harbor Laboratory Press 2021-03-15 <![CDATA[ Comprehensive mouse gut metagenomecatalog reveals major difference to thehuman counterpart ]]> https://biorxiv.org/content/10.1101/2021.03.18.435958v1?rss=1 Trajkovski, M. Kieser, S. Zdobnov, E. 2021-03-18 doi:10.1101/2021.03.18.435958 Cold Spring Harbor Laboratory Press 2021-03-18 <![CDATA[ Revisiting the role of Toxoplasma gondii ERK7 in the maintenance and stability of the apical complex ]]> https://biorxiv.org/content/10.1101/2021.03.22.436543v1?rss=1 Soldati-Favre, D. Dos Santos Pacheco, N. Tosetti, N. Krishnan, A. Haase, R. 2021-03-24 doi:10.1101/2021.03.22.436543 Cold Spring Harbor Laboratory Press 2021-03-24 <![CDATA[ TRIM28-dependent SUMOylation protects the adult ovary from the male pathway ]]> https://biorxiv.org/content/10.1101/2021.03.24.436749v1?rss=1 Rossitto, M. Dejardin, S. Rands, C. M. Legras, S. Migale, R. Rafiee, M.-R. Neirijnck, Y. Pruvost, A. Nguyen, A. L. Bossis, G. Cammas, F. M. Le Gallic, L. Wilhelm, D. Boizet-Bonhoure, B. Lovell-Badge, R. Nef, S. Poulat, F. 2021-03-24 doi:10.1101/2021.03.24.436749 Cold Spring Harbor Laboratory Press 2021-03-24 <![CDATA[ Comparative multi-tissue profiling reveals extensive tissue-specificity in transcriptome reprogramming upon cold exposure ]]> https://biorxiv.org/content/10.1101/2021.03.26.437139v1?rss=1 Trajkovski, M. Hadadi, N. Steinbach, K. Salinas, G. Merkler, D. Spiljar, M. 2021-03-29 doi:10.1101/2021.03.26.437139 Cold Spring Harbor Laboratory Press 2021-03-29 <![CDATA[ Functional dynamics of brain networks associated with carry-over effects of negative events on subsequent resting state. ]]> https://biorxiv.org/content/10.1101/2021.03.26.437275v1?rss=1 Gaviria, J. Rey, G. Bolton, T. Van De Ville, D. Vuilleumier, P. 2021-03-29 doi:10.1101/2021.03.26.437275 Cold Spring Harbor Laboratory Press 2021-03-29 <![CDATA[ MiR-137 and miR-122, two outer subventricular zone-enriched non-coding RNAs, regulate basal progenitor expansion and neuronal differentiation ]]> https://biorxiv.org/content/10.1101/2021.04.01.438039v1?rss=1 Tomasello, U. Klingler, E. Niquille, M. Mule, N. de Vevey, L. Prados, J. Santinha, A. J. Platt, R. J. Borrell, V. Jabaudon, D. Dayer, A. 2021-04-02 doi:10.1101/2021.04.01.438039 Cold Spring Harbor Laboratory Press 2021-04-02 <![CDATA[ Optogenetic stimulation of BLA terminals in the BNST elicits long term synaptic plasticity and restores synaptic alterations induced by adolescent Shank3 downregulation ]]> https://biorxiv.org/content/10.1101/2021.04.02.438185v1?rss=1 Glangetas, C. Contestabile, A. Espinosa, P. Casarotto, G. Musardo, S. Bellone, C. 2021-04-02 doi:10.1101/2021.04.02.438185 Cold Spring Harbor Laboratory Press 2021-04-02 <![CDATA[ Myeloid and endothelial cells cooperate to promote hematopoietic stem cells expansion in the fetal niche. ]]> https://biorxiv.org/content/10.1101/2021.04.07.438809v1?rss=1 Cacialli, P. Mailhe, M.-P. Golub, R. Bertrand, J. Y. 2021-04-07 doi:10.1101/2021.04.07.438809 Cold Spring Harbor Laboratory Press 2021-04-07 <![CDATA[ Motor usage imprints microtubule stability in the shaft ]]> https://biorxiv.org/content/10.1101/2021.04.09.439170v1?rss=1 Andreu-Carbo, M. Fernandes, S. Celluz, M.-C. Kruse, K. Aumeier, C. 2021-04-11 doi:10.1101/2021.04.09.439170 Cold Spring Harbor Laboratory Press 2021-04-11 <![CDATA[ YTHDC2 Is Essential for Pachytene Progression and Prevents Aberrant Microtubule-Driven Telomere Clustering in Male Meiosis ]]> https://biorxiv.org/content/10.1101/2021.04.12.439470v1?rss=1 Liu, R. Kasowitz, S. D. Homolka, D. Leu, N. A. Shaked, J. T. Ruthel, G. Jain, D. Keeney, S. Luo, M. Wang, J. 2021-04-12 doi:10.1101/2021.04.12.439470 Cold Spring Harbor Laboratory Press 2021-04-12 <![CDATA[ Investigating the two regimes of fibrin clot lysis: an experimental and computational approach ]]> https://biorxiv.org/content/10.1101/2021.04.14.439801v1?rss=1 Raynaud, F. Rousseau, A. Monteyne, D. Perez-Morga, D. Zouaoui Boudjeltia, K. Chopard, B. 2021-04-14 doi:10.1101/2021.04.14.439801 Cold Spring Harbor Laboratory Press 2021-04-14 <![CDATA[ Specific transcriptomic signatures and dual regulation of steroidogenesis between fetal and adult mouse Leydig cells ]]> https://biorxiv.org/content/10.1101/2021.04.14.439819v1?rss=1 Sararols, P. Stevant, I. Neirijnck, Y. Rebourcet, D. Darbey, A. Curley, M. K. Kuhne, F. Dermitzakis, E. Smith, L. B. Nef, S. 2021-04-14 doi:10.1101/2021.04.14.439819 Cold Spring Harbor Laboratory Press 2021-04-14 <![CDATA[ The UBAP2L ortholog PQN-59 contributes to stress granule assembly and development in C. elegans ]]> https://biorxiv.org/content/10.1101/2021.04.16.440123v1?rss=1 Abbatemarco, S. Bondaz, A. Schwager, F. Wang, J. Hammell, C. M. Gotta, M. 2021-04-16 doi:10.1101/2021.04.16.440123 Cold Spring Harbor Laboratory Press 2021-04-16 <![CDATA[ Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace ]]> https://biorxiv.org/content/10.1101/2021.04.28.441853v1?rss=1 Williams, R. L. Heimhalt, M. Berndt, A. Wagstaff, J. L. Anandapadamanaban, M. Perisic, O. Maslen, S. McLaughlin, S. H. Yu, C. W.-H. Masson, G. R. Boland, A. Ni, X. Yamashita, K. Murshudov, G. N. Skehel, M. Freund, S. M. 2021-04-30 doi:10.1101/2021.04.28.441853 Cold Spring Harbor Laboratory Press 2021-04-30 <![CDATA[ 3D printed pacifier-shaped mouthpiece for fMRI-compatible gustometers ]]> https://biorxiv.org/content/10.1101/2021.05.02.442330v1?rss=1 Munoz Tord, D. Coppin, G. Pool, E. R. Mermoud, C. Pataky, Z. Sander, D. Delplanque, S. 2021-05-02 doi:10.1101/2021.05.02.442330 Cold Spring Harbor Laboratory Press 2021-05-02 <![CDATA[ Differential contributions of ventral striatum subregions to the motivational and hedonic components of the affective processing of the reward ]]> https://biorxiv.org/content/10.1101/2021.05.02.442349v1?rss=1 Pool, E. R. Munoz Tord, D. Delplanque, S. Stussi, Y. Cereghetti, D. Vuilleumier, P. Sander, D. 2021-05-02 doi:10.1101/2021.05.02.442349 Cold Spring Harbor Laboratory Press 2021-05-02 <![CDATA[ Vacuole-specific lipid release for tracking intracellular lipid metabolism and transport in Saccharomyces cerevisiae ]]> https://biorxiv.org/content/10.1101/2021.05.04.442581v1?rss=1 Girik, V. Feng, S. Hariri, H. Henne, W. M. Riezman, H. 2021-05-04 doi:10.1101/2021.05.04.442581 Cold Spring Harbor Laboratory Press 2021-05-04 <![CDATA[ A Discriminative Characterization of Heschl's Gyrus Morphology using Spectral Graph Features ]]> https://biorxiv.org/content/10.1101/2021.05.04.442618v1?rss=1 Maghsadhagh, S. Dalboni da Rocha, J. L. Benner, J. Schneider, P. Golestani, N. Behjat, H. 2021-05-05 doi:10.1101/2021.05.04.442618 Cold Spring Harbor Laboratory Press 2021-05-05 <![CDATA[ The CTPase activity of ParB acts as a timing mechanism to control the dynamics and function of prokaryotic DNA partition complexes ]]> https://biorxiv.org/content/10.1101/2021.05.05.442810v1?rss=1 Osorio-Valeriano, M. Altegoer, F. Das, C. K. Steinchen, W. Panis, G. Connolley, L. Giacomelli, G. Feddersen, H. Corrales-Guerrero, L. Giammarinaro, P. Hanssmann, J. Bramkamp, M. Viollier, P. H. Murray, S. Schäfer, L. V. Bange, G. Thanbichler, M. 2021-05-05 doi:10.1101/2021.05.05.442810 Cold Spring Harbor Laboratory Press 2021-05-05 <![CDATA[ PQN-59 antagonizes microRNA-mediated repression and functions in stress granule formation during C. elegans development ]]> https://biorxiv.org/content/10.1101/2021.05.14.444139v1?rss=1 Hammell, C. M. Carlston, C. Weinmann, R. Stec, N. Abbatemarco, S. Schwager, F. Wang, J. Ouyang, H. Gotta, M. 2021-05-14 doi:10.1101/2021.05.14.444139 Cold Spring Harbor Laboratory Press 2021-05-14 <![CDATA[ Loricarioid catfish evolved skin denticles that recapitulate teeth at the structural, developmental, and genetic levels ]]> https://biorxiv.org/content/10.1101/2021.05.17.444419v1?rss=1 Rivera-Rivera, C. J. Guevara-Delgadillo, N. I. Bahechar, I. A. Shea, C. A. Montoya-Burgos, J. I. 2021-05-17 doi:10.1101/2021.05.17.444419 Cold Spring Harbor Laboratory Press 2021-05-17 <![CDATA[ Motivated semantic control: Exploring the effects of extrinsic reward and self-reference on semantic retrieval in semantic aphasia ]]> https://biorxiv.org/content/10.1101/2021.05.25.444996v1?rss=1 Souter, N. E. Stampacchia, S. Hallam, G. Thompson, H. Smallwood, J. Jefferies, E. 2021-05-28 doi:10.1101/2021.05.25.444996 Cold Spring Harbor Laboratory Press 2021-05-28 <![CDATA[ Location and function of all Plasmodium kinesins: key roles in parasite proliferation, polarity, and transmission ]]> https://biorxiv.org/content/10.1101/2021.05.26.445751v1?rss=1 Zeeshan, M. Rashpa, R. Ferguson, D. J. P. Abel, S. Chahine, Z. Brady, D. Moores, C. A. Le Roch, K. G. Brochet, M. Holder, A. A. Tewari, R. 2021-05-27 doi:10.1101/2021.05.26.445751 Cold Spring Harbor Laboratory Press 2021-05-27 <![CDATA[ The complete sequence of a human genome ]]> https://biorxiv.org/content/10.1101/2021.05.26.445798v1?rss=1 Nurk, S. Koren, S. Rhie, A. Rautiainen, M. Bzikadze, A. V. Mikheenko, A. Vollger, M. R. Altemose, N. Uralsky, L. Gershman, A. Aganezov, S. Hoyt, S. J. Diekhans, M. Logsdon, G. A. Alonge, M. Antonarakis, S. E. Borchers, M. Bouffard, G. G. Brooks, S. Y. Caldas, G. V. Cheng, H. Chin, C.-S. Chow, W. de Lima, L. G. Dishuck, P. C. Durbin, R. Dvorkina, T. Fiddes, I. T. Formenti, G. Fulton, R. S. Fungtammasan, A. Garrison, E. Grady, P. G. S. Graves-Lindsay, T. A. Hall, I. M. Hansen, N. F. Hartley, G. A. Haukness, M. Howe, K. Hunkapiller, M. W. Jain, C. Jain, M. 2021-05-27 doi:10.1101/2021.05.26.445798 Cold Spring Harbor Laboratory Press 2021-05-27 <![CDATA[ Microarrayed human bone marrow organoids for modeling blood stem cell dynamics ]]> https://biorxiv.org/content/10.1101/2021.05.26.445803v1?rss=1 Giger, S. Hofer, M. Miljkovic-Licina, M. Hoehnel, S. Brandenberg, N. Guiet, R. Ehrbar, M. Kleiner, E. Gegenschatz, K. Matthes, T. Lutolf, M. P. 2021-05-27 doi:10.1101/2021.05.26.445803 Cold Spring Harbor Laboratory Press 2021-05-27 <![CDATA[ Global analysis of the zinc homeostasis network in Pseudomonas aeruginosa and its gene expression dynamics ]]> https://biorxiv.org/content/10.1101/2021.05.28.446167v1?rss=1 Ducret, V. Abdou, M. Goncalves Milho, C. Leoni, S. Martin--Pelaud, O. Sandoz, A. Segovia Campos, I. Tercier Waeber, M. Valentini, M. Perron, K. 2021-05-28 doi:10.1101/2021.05.28.446167 Cold Spring Harbor Laboratory Press 2021-05-28 <![CDATA[ Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR ]]> https://biorxiv.org/content/10.1101/2021.05.30.445237v1?rss=1 Scherer, M. Gasparoni, G. Rahmouni, S. Shashkova, T. Arnoux, M. Louis, E. Nostaeva, A. Avalos, D. Dermitzakis, E. T. Aulchenko, Y. S. Lengauer, T. Lyons, P. A. Georges, M. Walter, J. 2021-05-30 doi:10.1101/2021.05.30.445237 Cold Spring Harbor Laboratory Press 2021-05-30 <![CDATA[ Structure of the phosphoinositide 3-kinase p110γ-p101 complex reveals molecular mechanism of GPCR activation ]]> https://biorxiv.org/content/10.1101/2021.06.01.446612v1?rss=1 Rathinaswamy, M. K. Dalwadi, U. Fleming, K. D. Adams, C. Stariha, J. T. Pardon, E. Baek, M. Vadas, O. DiMaio, F. Steyaert, J. Hansen, S. D. Yip, C. K. Burke, J. E. 2021-06-01 doi:10.1101/2021.06.01.446612 Cold Spring Harbor Laboratory Press 2021-06-01 <![CDATA[ Dual control of MAPK activities by AP2C1 and MKP1 MAPK phosphatases regulates defence responses in Arabidopsis ]]> https://biorxiv.org/content/10.1101/2021.06.03.446911v1?rss=1 Ayatollahi, Z. Kazanaviciute, V. Shubchynskyy, V. Kvederaviciute, K. Schwanninger, M. Rozhon, W. Stumpe, M. Mauch, F. Bartels, S. Ulm, R. Balazadeh, S. Mueller-Roeber, B. Meskiene, I. Schweighofer, A. 2021-06-03 doi:10.1101/2021.06.03.446911 Cold Spring Harbor Laboratory Press 2021-06-03 <![CDATA[ Western Amazon was a center of Neotropical fish dispersal, as evidenced by the continental-wide time-stratified biogeographic analysis of the hyper-diverse Hypostomus catfish ]]> https://biorxiv.org/content/10.1101/2021.06.03.446980v1?rss=1 Jardim de Queiroz, L. Meyer, X. Cardoso, Y. P. Bahechar, I. A. Covain, R. Parente, T. E. Torrente-Vilara, G. Buckup, P. A. Montoya-Burgos, J. I. 2021-06-03 doi:10.1101/2021.06.03.446980 Cold Spring Harbor Laboratory Press 2021-06-03 <![CDATA[ Super-cells untangle large and complex single-cell transcriptome networks ]]> https://biorxiv.org/content/10.1101/2021.06.07.447430v1?rss=1 Bilous, M. Tran, L. Cianciaruso, C. Carmona, S. J. Pittet, M. J. Gfeller, D. 2021-06-08 doi:10.1101/2021.06.07.447430 Cold Spring Harbor Laboratory Press 2021-06-08 <![CDATA[ The Cost of Untracked Diversity in Brain-Imaging Prediction ]]> https://biorxiv.org/content/10.1101/2021.06.16.448764v1?rss=1 Benkarim, O. Paquola, C. Park, B.-y. Kebets, V. Hong, S.-J. Vos de Wael, R. Zhang, S. Yeo, B. T. T. Eickenberg, M. Ge, T. Poline, J.-B. Bernhardt, B. Bzdok, D. 2021-06-17 doi:10.1101/2021.06.16.448764 Cold Spring Harbor Laboratory Press 2021-06-17 <![CDATA[ PLEKHA5, PLEKHA6 and PLEKHA7 bind to PDZD11 to target the Menkes ATPase ATP7A to the cell periphery and regulate copper homeostasis ]]> https://biorxiv.org/content/10.1101/2021.06.17.448791v1?rss=1 Citi, S. Sluysmans, S. Mean, I. Xiao, T. Boukhatemi, A. Ferreira, F. Jond, L. Chang, C. J. 2021-06-17 doi:10.1101/2021.06.17.448791 Cold Spring Harbor Laboratory Press 2021-06-17 <![CDATA[ Pressure and curvature control of contact inhibition in epithelia growing under spherical confinement ]]> https://biorxiv.org/content/10.1101/2021.06.17.448824v1?rss=1 Di Meglio, I. Trushko, A. Guillamat, P. Blanch-Mercader, C. Roux, A. 2021-06-17 doi:10.1101/2021.06.17.448824 Cold Spring Harbor Laboratory Press 2021-06-17 <![CDATA[ Genetic Analyses of Epigenetic Predictors that Estimate Aging, Metabolic Traits, and Lifespan ]]> https://biorxiv.org/content/10.1101/2021.06.23.449634v1?rss=1 Mozhui, K. Lu, A. Li, C. Z. Haghani, A. Sandoval-Sierra, J. V. Williams, R. W. Horvath, S. 2021-06-24 doi:10.1101/2021.06.23.449634 Cold Spring Harbor Laboratory Press 2021-06-24 <![CDATA[ Enhanced fitness of SARS-CoV-2 variant of concern B.1.1.7, but not B.1.351, in animal models ]]> https://biorxiv.org/content/10.1101/2021.06.28.450190v1?rss=1 Ulrich, L. Halwe, N. J. Taddeo, A. Ebert, N. Schön, J. Devisme, C. Trüeb, B. S. Hoffmann, B. Wider, M. Bekliz, M. Essaidi-Laziosi, M. Schmidt, M. L. Niemeyer, D. Corman, V. M. Kraft, A. Godel, A. Laloli, L. Kelly, J. N. Breithaupt, A. Wylezich, C. Berenguer Veiga, I. M. Gultom, M. Adea, K. Meyer, B. Eberhardt, C. Thomann, L. Gsell-Albert, M. Labroussaa, F. Jores, J. Summerfield, A. Drosten, C. Eckerle, I. A. Dijkman, R. Hoffmann, D. Thiel, V. Beer, M. Benarafa, C. 2021-06-28 doi:10.1101/2021.06.28.450190 Cold Spring Harbor Laboratory Press 2021-06-28 <![CDATA[ The Dictyostelium discoideum E3 ubiquitin ligase TrafE coordinates endolysosomal damage response and cell-autonomous immunity to Mycobacterium marinum. ]]> https://biorxiv.org/content/10.1101/2021.06.29.450281v1?rss=1 Raykov, L. Mottet, M. Nitschke, J. Soldati, T. 2021-06-29 doi:10.1101/2021.06.29.450281 Cold Spring Harbor Laboratory Press 2021-06-29 <![CDATA[ Clonally expanded virus-specific CD8 T cells acquire diverse transcriptional phenotypes during acute, chronic, and latent infections ]]> https://biorxiv.org/content/10.1101/2021.06.29.450285v1?rss=1 Kuhn, R. Sandu, I. Agrafiotis, A. Hong, K.-L. Neumeier, D. Merkler, D. Oxenius, A. Reddy, S. T. Yermanos, A. 2021-06-30 doi:10.1101/2021.06.29.450285 Cold Spring Harbor Laboratory Press 2021-06-30 <![CDATA[ Healthcare experience disrupts representational similarity between one's and others' pain in anterior insula ]]> https://biorxiv.org/content/10.1101/2021.07.01.450687v1?rss=1 Corradi-Dell'Acqua, C. Hofstetter, C. Sharvit, G. Hugli, O. Vuilleumier, P. 2021-07-04 doi:10.1101/2021.07.01.450687 Cold Spring Harbor Laboratory Press 2021-07-04 <![CDATA[ Mitotic chromosome condensation requires phosphorylation of the centromeric protein KNL-2 in C. elegans ]]> https://biorxiv.org/content/10.1101/2021.07.01.450752v1?rss=1 Wenda, J. M. Prosee, R. F. Gabus, C. Steiner, F. A. 2021-07-01 doi:10.1101/2021.07.01.450752 Cold Spring Harbor Laboratory Press 2021-07-01 <![CDATA[ Mice and primates use distinct strategies for visual segmentation ]]> https://biorxiv.org/content/10.1101/2021.07.04.451059v1?rss=1 Luongo, F. J. Liu, L. Ho, C. L. A. Hesse, J. K. Wekselblatt, J. B. Lanfranchi, F. Huber, D. K. Tsao, D. Y. 2021-07-05 doi:10.1101/2021.07.04.451059 Cold Spring Harbor Laboratory Press 2021-07-05 <![CDATA[ PLK1 controls centriole distal appendage formation and centrobin removal via independent pathways ]]> https://biorxiv.org/content/10.1101/2021.07.06.451279v1?rss=1 LeRoux-Bourdieu, M. Harry, D. Meraldi, P. 2021-07-06 doi:10.1101/2021.07.06.451279 Cold Spring Harbor Laboratory Press 2021-07-06 <![CDATA[ Critical Assessment of Metagenome Interpretation - the second round of challenges ]]> https://biorxiv.org/content/10.1101/2021.07.12.451567v1?rss=1 Meyer, F. Fritz, A. Deng, Z.-L. Koslicki, D. Gurevich, A. Robertson, G. Zhu, J. Jia, H. Kola, A. Limasset, A. Kolmogorov, M. Egan, R. Rosen, G. L. Cristian, A. Zhao, Z. Gray, M. A. Nissen, J. Zeller, G. Paoli, L. Ruscheweyh, H.-J. Milanese, A. Sunagawa, S. Alser, M. Shi, L. Chen, B. Wang, Z. Wang, Z. Huang, P. You, R. Sun, F. Zhu, S. Bertrand, D. Tong, C. Li, C. Nagarajan, N. Renard, B. Malcher-Miranda, F. Piro, V. C. Chikhi, R. Vicedomini, R. Wang, Z. Thomas, A. Tremblay, J. Dabrowski, P. W. Nurk, S. Jorgensen, T. S. Willassen, N. P. Klemetsen, T 2021-07-12 doi:10.1101/2021.07.12.451567 Cold Spring Harbor Laboratory Press 2021-07-12 <![CDATA[ The ternary complex CEP90, FOPNL and OFD1 specifies the future location of centriolar distal appendages, and promotes their assembly ]]> https://biorxiv.org/content/10.1101/2021.07.13.452210v1?rss=1 Le Borgne, P. Laporte, M. H. Greibill, L. Lemullois, M. Temagoult, M. Rosnet, O. Le Guennec, M. Lignieres, L. Chevreux, G. Koll, F. Hamel, V. Guichard, P. Tassin, A.-M. 2021-07-14 doi:10.1101/2021.07.13.452210 Cold Spring Harbor Laboratory Press 2021-07-14 <![CDATA[ APOE2, E3 and E4 differentially modulate cellular homeostasis, cholesterol metabolism and inflammatory response in isogenic iPSC-derived astrocytes ]]> https://biorxiv.org/content/10.1101/2021.07.17.452644v1?rss=1 E3>E2=KO) reduced iAstrocyte metabolic and clearance functions including glutamate uptake and receptor-mediated uptake of {beta}-amyloid aggregates. We performed unlabelled mass spectrometry-based proteomic analysis of iAstrocytes at baseline and after activation with interleukin-1{beta} (IL-1{beta}) showing a reduction of cholesterol and lipid metabolic and biosynthetic pathways, and an increase of immunoregulatory pathways at baseline (E4>E3>E2). Cholesterol efflux and biosynthesis were reduced in E4 iAstrocytes, and subcellular localization of cholesterol in lysosomes was increased. In APOE-KO iAstrocytes, APOE-independent mechanisms showed to be proficient in mediating cholesterol biosynthesis and efflux. Proteomic analysis of IL-1{beta}-treated iAstrocytes showed an increase of cholesterol/lipid metabolism and biosynthesis as well as inflammatory pathways. Furthermore, cholesterol efflux, which was reduced in APOE4 iAstrocytes at baseline, was alleviated in activated E4 iAstrocytes. Inflammatory cytokine release was exacerbated upon IL-1{beta} treatment in E4 iAstrocytes (E4>E3>E2>KO), in line with the proteomic data. Taken together, we show that APOE plays a major role in several physiological and metabolic processes in human astrocytes with APOE4 pushing iAstrocytes to a disease-relevant phenotype, causing dysregulated cholesterol/lipid homeostasis, increased inflammatory signalling and reduced {beta}-amyloid uptake while APOE2 iAstrocytes show opposing effects. Our study provides a new reference for AD-relevant proteomic and metabolic changes, mediated by the three main APOE isoforms in human astrocytes. ]]> de Leeuw, S. Kirschner, A. W. Lindner, K. Rust, R. Wolski, W. E. Gavin, A.-C. Nitsch, R. M. Tackenberg, C. 2021-07-18 doi:10.1101/2021.07.17.452644 Cold Spring Harbor Laboratory Press 2021-07-18 <![CDATA[ Ultrastructure expansion microscopy of Plasmodium gametocytes reveals the molecular architecture of a microtubule organisation centre coordinating mitosis with axoneme assembly ]]> https://biorxiv.org/content/10.1101/2021.07.21.453039v1?rss=1 Rashpa, R. Brochet, M. 2021-07-21 doi:10.1101/2021.07.21.453039 Cold Spring Harbor Laboratory Press 2021-07-21 <![CDATA[ CoverageMaster: comprehensive CNV detection and visualization from NGS short reads for genetic medicine applications ]]> https://biorxiv.org/content/10.1101/2021.07.21.453195v1?rss=1 Rapti, M. Meylan Merlini, J. Ranza, E. Antonarakis, S. E. Santoni, F. A. 2021-07-22 doi:10.1101/2021.07.21.453195 Cold Spring Harbor Laboratory Press 2021-07-22 <![CDATA[ Microtubule-based mitotic spindles contain a micron-sized mixed-nucleotide zone ]]> https://biorxiv.org/content/10.1101/2021.07.23.453504v1?rss=1 Castrogiovanni, C. Inchingolo, A. V. Harrison, J. U. Dudka, D. Sen, O. Burroughs, N. J. McAinsh, A. D. Meraldi, P. 2021-07-23 doi:10.1101/2021.07.23.453504 Cold Spring Harbor Laboratory Press 2021-07-23 <![CDATA[ Size of the cell nucleus and its effect on the chromatin structure in living cells. ]]> https://biorxiv.org/content/10.1101/2021.07.27.453925v1?rss=1 Efremov, A. K. Hovan, L. Yan, J. 2021-07-27 doi:10.1101/2021.07.27.453925 Cold Spring Harbor Laboratory Press 2021-07-27 <![CDATA[ A novel anti-influenza combined therapy assessed by single cell RNA-sequencing ]]> https://biorxiv.org/content/10.1101/2021.07.27.453967v1?rss=1 Medaglia, C. Kolpakov, I. Zhu, Y. Constant, S. Huang, S. Zwygart, A. C.-A. Cagno, V. Dermitzakis, E. Stellacci, F. Xenarios, I. Tapparel, C. 2021-07-27 doi:10.1101/2021.07.27.453967 Cold Spring Harbor Laboratory Press 2021-07-27 <![CDATA[ Phase transition specified by a binary code patterns the vertebrate eye cup ]]> https://biorxiv.org/content/10.1101/2021.08.12.455556v1?rss=1 Balasubramanian, R. Min, X. Quinn, P. M. J. Giudice, Q. L. Tao, C. Polanco, K. Makrides, N. Peregrin, J. Bouaziz, M. Mao, Y. Wang, Q. Costa, B. L. Buenaventura, D. Wang, F. Ma, L. Tsang, S. H. Fabre, P. J. Zhang, X. 2021-08-13 doi:10.1101/2021.08.12.455556 Cold Spring Harbor Laboratory Press 2021-08-13 <![CDATA[ DEVELOPMENTAL AND EVOLUTIONARY COMPARATIVE ANALYSIS OF A HOXD REGULATORY LANDSCAPE IN MAMMALS AND BIRDS ]]> https://biorxiv.org/content/10.1101/2021.08.12.456039v1?rss=1 Hintermann, A. Guerreiro, I. Bolt, C. C. Gitto, S. Duboule, D. Beccari, L. 2021-08-12 doi:10.1101/2021.08.12.456039 Cold Spring Harbor Laboratory Press 2021-08-12 <![CDATA[ Sequential in-cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster ]]> https://biorxiv.org/content/10.1101/2021.08.13.456193v1?rss=1 Lhopitallier, R. Beccari, L. Lopez-Delisle, L. Mascrez, B. Zakany, J. Gitto, S. Duboule, D. 2021-08-13 doi:10.1101/2021.08.13.456193 Cold Spring Harbor Laboratory Press 2021-08-13 <![CDATA[ The temporal dynamics of the Stroop effect from childhood to young and older adulthood ]]> https://biorxiv.org/content/10.1101/2021.08.13.456209v1?rss=1 Menetre, E. Laganaro, M. 2021-08-13 doi:10.1101/2021.08.13.456209 Cold Spring Harbor Laboratory Press 2021-08-13 <![CDATA[ An ancient dental signalling centre supports homology of an enamel knot in sharks ]]> https://biorxiv.org/content/10.1101/2021.08.13.456270v1?rss=1 Thiery, A. P. Standing, A. S. I. Cooper, R. L. Fraser, G. J. 2021-08-16 doi:10.1101/2021.08.13.456270 Cold Spring Harbor Laboratory Press 2021-08-16 <![CDATA[ Microbial loop of Proterozoic ocean analogue ]]> https://biorxiv.org/content/10.1101/2021.08.17.456685v1?rss=1 Saini, J. S. Hassler, C. Cable, R. Fourquez, M. Danza, F. Roman, S. Tonolla, M. Storelli, N. Jacquet, S. Zdobnov, E. M. Duhaime, M. B. 2021-08-18 doi:10.1101/2021.08.17.456685 Cold Spring Harbor Laboratory Press 2021-08-18 <![CDATA[ Regulation of membrane scission in yeast endocytosis ]]> https://biorxiv.org/content/10.1101/2021.08.18.454332v1?rss=1 Menon, D. Kaksonen, M. 2021-08-18 doi:10.1101/2021.08.18.454332 Cold Spring Harbor Laboratory Press 2021-08-18 <![CDATA[ A small protein, derived from an alternative 53BP1 promoter transcript and expressed via translational reinitiation on an internal overlapping ORF, modulates proteasome activity. ]]> https://biorxiv.org/content/10.1101/2021.08.23.457304v1?rss=1 Inchingolo, M. A. Adamczewski, M. Humphreys, T. Jaquier-Gubler, P. Curran, J. A. 2021-08-23 doi:10.1101/2021.08.23.457304 Cold Spring Harbor Laboratory Press 2021-08-23 <![CDATA[ The connecting cilium inner scaffold provides a structural foundation to maintain photoreceptor integrity ]]> https://biorxiv.org/content/10.1101/2021.08.27.457921v1?rss=1 Mercey, O. Kostic, C. Bertiaux, E. Giroud, A. Sadian, Y. Chang, N. Arsenijevic, Y. Guichard, P. Hamel, V. 2021-08-28 doi:10.1101/2021.08.27.457921 Cold Spring Harbor Laboratory Press 2021-08-28 <![CDATA[ Dynamic analysis of lower leg muscles response to whole body vibration stimulation at different frequencies and postures: implications for training ]]> https://biorxiv.org/content/10.1101/2021.08.31.458312v1?rss=1 Rigoni, I. Bonci, T. Bifulco, P. Fratini, A. 2021-09-01 doi:10.1101/2021.08.31.458312 Cold Spring Harbor Laboratory Press 2021-09-01 <![CDATA[ An integrative approach to mosquito dynamics reveals differences in people's everyday experiences of mosquitoes ]]> https://biorxiv.org/content/10.1101/2021.09.06.459057v1?rss=1 Evans, M. V. Bhatnagar, S. Drake, J. M. Murdock, C. C. Mukherjee, S. 2021-09-06 doi:10.1101/2021.09.06.459057 Cold Spring Harbor Laboratory Press 2021-09-06 <![CDATA[ Phase-amplitude coupling and phase synchronization between medial temporal, frontal and posterior brain regions support episodic autobiographical memory recall ]]> https://biorxiv.org/content/10.1101/2021.09.06.459104v1?rss=1 Roehri, N. Bréchet, L. Seeber, M. Pascual-Leone, A. Michel, C. M. 2021-09-06 doi:10.1101/2021.09.06.459104 Cold Spring Harbor Laboratory Press 2021-09-06 <![CDATA[ Oxytocin neurons mediates the effect of social isolation via the VTA circuits ]]> https://biorxiv.org/content/10.1101/2021.09.06.459105v1?rss=1 Musardo, S. Contestabile, A. Mairesse, J. Baud, O. Bellone, C. 2021-09-06 doi:10.1101/2021.09.06.459105 Cold Spring Harbor Laboratory Press 2021-09-06 <![CDATA[ Generation and diversification of recombinant monoclonal antibodies for studying mitosis ]]> https://biorxiv.org/content/10.1101/2021.09.10.455288v1?rss=1 DeLuca, K. F. Mick, J. E. Hodges, A. L. Lima, W. C. Sherman, L. Schaller, K. L. Anderson, S. M. Zhao, N. Stasevich, T. J. Varma, D. Gorbsky, G. J. Nilsson, J. DeLuca, J. G. 2021-09-11 doi:10.1101/2021.09.10.455288 Cold Spring Harbor Laboratory Press 2021-09-11 <![CDATA[ A liquid +TIP-network drives microtubule dynamics through tubulin condensation ]]> https://biorxiv.org/content/10.1101/2021.09.13.459419v1?rss=1 Miesch, J. Wimbish, R. T. Velluz, M.-C. Aumeier, C. 2021-09-13 doi:10.1101/2021.09.13.459419 Cold Spring Harbor Laboratory Press 2021-09-13 <![CDATA[ The model arbuscular mycorrhizal fungus Rhizophagus irregularis harbours endosymbiotic bacteria with a highly reduce genome ]]> https://biorxiv.org/content/10.1101/2021.09.13.460061v1?rss=1 Savary, R. Masclaux, F. G. Sanders, I. R. 2021-09-13 doi:10.1101/2021.09.13.460061 Cold Spring Harbor Laboratory Press 2021-09-13 <![CDATA[ Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad ]]> https://biorxiv.org/content/10.1101/2021.09.15.460431v1?rss=1 Mayere, C. Regard, V. Perea-Gomez, A. Bunce, C. Neirijnck, Y. Djari, C. Sararols, P. Reeves, R. Greenaway, S. Simon, M. Siggers, P. Condrea, D. Kühne, F. Gantar, I. Tang, F. Stevant, I. Batti, L. Ghyselinck, N. B. Wilhelm, D. Greenfield, A. Capel, B. Chaboissier, M.-C. Nef, S. 2021-09-17 doi:10.1101/2021.09.15.460431 Cold Spring Harbor Laboratory Press 2021-09-17 <![CDATA[ High-order functional interactions in ageing explained via alterations in the connectome in a whole-brain model ]]> https://biorxiv.org/content/10.1101/2021.09.15.460435v1?rss=1 Gatica, M. Rosas, F. E. Mediano, P. A. M. Diez, I. Swinnen, S. P. Orio, P. Cofre, R. Cortes, J. M. 2021-09-17 doi:10.1101/2021.09.15.460435 Cold Spring Harbor Laboratory Press 2021-09-17 <![CDATA[ Neural oscillation coupling selectively predicts speech reception in young children with Autism Spectrum Disorder ]]> https://biorxiv.org/content/10.1101/2021.09.27.461214v1?rss=1 Wang, X. Delgado Saa, J. F. Marchesotti, S. Kojovic, N. Sperdin, H. F. Rihs, T. A. Schaer, M. Giraud, A.-L. 2021-09-27 doi:10.1101/2021.09.27.461214 Cold Spring Harbor Laboratory Press 2021-09-27 <![CDATA[ Repression of the Hox gene abd-A by ELAV-mediated Transcriptional Interference ]]> https://biorxiv.org/content/10.1101/2021.09.29.462302v1?rss=1 Castro Alvarez, J. J. Revel, M. Cleard, F. Pauli, D. Karch, F. Maeda, R. K. 2021-09-30 doi:10.1101/2021.09.29.462302 Cold Spring Harbor Laboratory Press 2021-09-30 <![CDATA[ The European Prevention of Alzheimer's Dementia (EPAD) MRI Dataset and Processing Workflow ]]> https://biorxiv.org/content/10.1101/2021.09.29.462349v1?rss=1 Lorenzini, L. Ingala, S. Wink, A. M. Kuijer, J. Wottschel, V. Dijsselhof, M. Sudre, C. Haller, S. Molinuevo, J. L. Gispert, J. D. Cash, D. M. Thomas, D. L. Vos, S. B. Prados, F. Petr, J. Wolz, R. Palombit, A. Schwarz, A. Chetelat, G. Payoux, P. Di perri, C. Wardlaw, J. Frisoni, G. B. Foley, C. Fox, N. C. Ritchie, C. Pernet, C. Waldman, A. Barkhof, F. Mutsaerts, H. J. 2021-10-01 doi:10.1101/2021.09.29.462349 Cold Spring Harbor Laboratory Press 2021-10-01 <![CDATA[ Metacognition and the effect of incentive motivation in two compulsive disorders: gambling disorder and obsessive-compulsive disorder ]]> https://biorxiv.org/content/10.1101/2021.09.30.462582v1?rss=1 Hoven, M. de Boer, N. S. Goudriaan, A. E. Denys, D. Lebreton, M. van Holst, R. J. Luigjes, J. 2021-10-01 doi:10.1101/2021.09.30.462582 Cold Spring Harbor Laboratory Press 2021-10-01 <![CDATA[ Pantothenate biosynthesis is critical for chronic infection by the neurotropic parasite Toxoplasma gondii ]]> https://biorxiv.org/content/10.1101/2021.10.04.462976v1?rss=1 Lunghi, M. Kloehn, J. Krishnan, A. Varesio, E. Vadas, O. Soldati-Favre, D. 2021-10-04 doi:10.1101/2021.10.04.462976 Cold Spring Harbor Laboratory Press 2021-10-04 <![CDATA[ Single-cell profiling in COVID-19 associated acute kidney injury reveals patterns of tubule injury and repair in human ]]> https://biorxiv.org/content/10.1101/2021.10.05.463150v1?rss=1 Legouis, D. Rinaldi, A. Arnoux, G. Verissimo, T. Scotti-Gerber, J. Faivre, A. Schibler, M. Rinaldi, A. Naesens, M. Koppitch, K. Pugin, J. McMahon, A. P. Moll, S. de Seigneux, S. Cippa, P. E. 2021-10-06 doi:10.1101/2021.10.05.463150 Cold Spring Harbor Laboratory Press 2021-10-06 <![CDATA[ SFI1 and centrin form a distal end complex critical for proper centriole architecture and ciliogenesis ]]> https://biorxiv.org/content/10.1101/2021.10.05.463184v1?rss=1 Bouhlel, I. Laporte, M. Bertiaux, E. Giroud, A. Borgers, S. Azimzadeh, J. Borneans, M. Guichard, P. Paoletti, A. Hamel, v. 2021-10-05 doi:10.1101/2021.10.05.463184 Cold Spring Harbor Laboratory Press 2021-10-05 <![CDATA[ Optimizing the live attenuated influenza A vaccine backbone for high-risk patient groups ]]> https://biorxiv.org/content/10.1101/2021.10.06.462766v1?rss=1 Bonifacio, J. P. Williams, N. Garnier, L. Hugues, S. Schmolke, M. Mazel-Sanchez, B. 2021-10-06 doi:10.1101/2021.10.06.462766 Cold Spring Harbor Laboratory Press 2021-10-06 <![CDATA[ Islet transplantation tolerance in animals with defined histocompatibility and diabetes ]]> https://biorxiv.org/content/10.1101/2021.10.08.463702v1?rss=1 Bhagchandani, P. Chang, C. Zhao, W. Ghila, L. Herrera, P. L. Chera, S. Kim, S. K. 2021-10-09 doi:10.1101/2021.10.08.463702 Cold Spring Harbor Laboratory Press 2021-10-09 <![CDATA[ Superresolution microscopy reveals partial preassembly and subsequent bending of the clathrin coat during endocytosis ]]> https://biorxiv.org/content/10.1101/2021.10.12.463947v1?rss=1 Mund, M. Tschanz, A. Wu, Y.-L. Frey, F. Mehl, J. L. Kaksonen, M. Avinoam, O. Schwarz, U. S. Ries, J. 2021-10-13 doi:10.1101/2021.10.12.463947 Cold Spring Harbor Laboratory Press 2021-10-13 <![CDATA[ Inhibition of TRPV4 rescues circuit and social deficits unmasked by acute inflammatory response in a Shank3 mouse model of Autism ]]> https://biorxiv.org/content/10.1101/2021.10.13.464215v1?rss=1 Tzanoulinou, S. Musardo, S. Contestabile, A. Bariselli, S. Casarotto, G. Magrinelli, E. Jiang, Y.-H. Jabaudon, D. Bellone, C. 2021-10-14 doi:10.1101/2021.10.13.464215 Cold Spring Harbor Laboratory Press 2021-10-14 <![CDATA[ Bacterial, phytoplankton, and viral dynamics of meromictic Lake Cadagno offer insights into the Proterozoic ocean microbial loop ]]> https://biorxiv.org/content/10.1101/2021.10.13.464336v1?rss=1 Saini, J. S. Hassler, C. Cable, R. N. Fourquez, M. Danza, F. Roman, S. Tonolla, M. Storelli, N. Jacquet, S. Zdobnov, E. M. Duhaime, M. B. 2021-10-15 doi:10.1101/2021.10.13.464336 Cold Spring Harbor Laboratory Press 2021-10-15 <![CDATA[ Dysfunctional temporal stages of eye-gaze perception in adults with ADHD: a high-density EEG study ]]> https://biorxiv.org/content/10.1101/2021.10.14.464365v1?rss=1 Mauriello, C. Pham, E. Kumar, S. Piguet, C. Aubry, J.-M. Dayer, A. Michel, C. Perroud, N. Berchio, C. 2021-10-16 doi:10.1101/2021.10.14.464365 Cold Spring Harbor Laboratory Press 2021-10-16 <![CDATA[ BBX proteins promote HY5-mediated UVR8 signaling in Arabidopsis ]]> https://biorxiv.org/content/10.1101/2021.10.14.464399v1?rss=1 Podolec, R. Wagnon, T. B. Leonardelli, M. Johansson, H. Ulm, R. 2021-10-14 doi:10.1101/2021.10.14.464399 Cold Spring Harbor Laboratory Press 2021-10-14 <![CDATA[ In situ architecture of the ciliary base reveals the stepwise assembly of IFT trains ]]> https://biorxiv.org/content/10.1101/2021.10.17.464685v1?rss=1 van den Hoek, H. Klena, N. Jordan, M. A. Alvarez Viar, G. Schaffer, M. Erdmann, P. S. Wan, W. Plitzko, J. M. Baumeister, W. Pigino, G. Hamel, V. Guichard, P. Engel, B. D. 2021-10-17 doi:10.1101/2021.10.17.464685 Cold Spring Harbor Laboratory Press 2021-10-17 <![CDATA[ Molecular atlas of the human brain vasculature at the single-cell level ]]> https://biorxiv.org/content/10.1101/2021.10.18.464715v1?rss=1 Wälchli, T. Ghobrial, M. Schwab, M. Takada, S. Zhong, H. Suntharalingham, S. Vetiska, S. Rodrigues Rodrigues, D. Rehrauer, H. Wu, R. Yu, K. Bisschop, J. Farnhammer, F. Regli, L. Schaller, K. Frei, K. Ketela, T. Bernstein, M. Kongkham, P. Carmeliet, P. Valiante, T. Dirks, P. B. Suva, M. L. Zadeh, G. Tabar, V. Schlapbach, R. De Bock, K. Fish, J. Monnier, P. Bader, G. Radovanovic, I. 2021-10-19 doi:10.1101/2021.10.18.464715 Cold Spring Harbor Laboratory Press 2021-10-19 <![CDATA[ Arnold tongue entrainment reveals dynamicalprinciples of the embryonic segmentation clock ]]> https://biorxiv.org/content/10.1101/2021.10.20.465101v1?rss=1 Sanchez, P. G. L. Mochulska, V. Mauffette Denis, C. Moenke, G. Tomita, T. Tsuchida-Straeten, N. Petersen, Y. Sonnen, I. Francois, P. Aulehla, A. 2021-10-21 doi:10.1101/2021.10.20.465101 Cold Spring Harbor Laboratory Press 2021-10-21 <![CDATA[ Optimal confidence for unaware visuomotor deviations ]]> https://biorxiv.org/content/10.1101/2021.10.22.465492v1?rss=1 Pereira, M. Skiba, R. Cojan, Y. Vuilleumier, P. Begue, I. 2021-10-24 doi:10.1101/2021.10.22.465492 Cold Spring Harbor Laboratory Press 2021-10-24 <![CDATA[ Tsetse RNA Virome: Novel Iflavirus Genomes in Glossina morsitans and Other Tsetse Species ]]> https://biorxiv.org/content/10.1101/2021.10.23.465572v1?rss=1 Manni, M. Zdobnov, E. M. 2021-10-24 doi:10.1101/2021.10.23.465572 Cold Spring Harbor Laboratory Press 2021-10-24 <![CDATA[ Comparing adaptive coding of reward in bipolar I disorder and schizophrenia ]]> https://biorxiv.org/content/10.1101/2021.10.24.465471v1?rss=1 Kaliuzhna, M. Kirschner, M. Tobler, P. N. Kaiser, S. 2021-10-25 doi:10.1101/2021.10.24.465471 Cold Spring Harbor Laboratory Press 2021-10-25 <![CDATA[ EEG microstate dynamics indicate a U-shaped path to propofol-induced loss of consciousness ]]> https://biorxiv.org/content/10.1101/2021.10.26.465841v1?rss=1 Artoni, F. Maillard, J. Britz, J. Seeber, M. Lysakowski, C. Brechet, L. Tramer, M. R. Michel, C. M. 2021-10-28 doi:10.1101/2021.10.26.465841 Cold Spring Harbor Laboratory Press 2021-10-28 <![CDATA[ Excessive inflammatory and metabolic responses to acute SARS-CoV-2 infection are associated with a distinct gut microbiota composition ]]> https://biorxiv.org/content/10.1101/2021.10.26.465865v1?rss=1 Albrich, W. C. Ghosh, T. S. Ahearn-Ford, S. Mikaeloff, F. Lunjani, N. Forde, B. Suh, N. Kleger, G.-R. Pietsch, U. Frischknecht, M. Garzoni, C. Forlenza, R. Horgan, M. Sadlier, C. Negro, T. R. Pugin, J. Wozniak, H. Cerny, A. Neogi, U. O'Toole, P. W. O'Mahony, L. 2021-10-26 doi:10.1101/2021.10.26.465865 Cold Spring Harbor Laboratory Press 2021-10-26 <![CDATA[ Ligand-induced unfolding mechanism of an RNA G-quadruplex ]]> https://biorxiv.org/content/10.1101/2021.10.26.465985v1?rss=1 Haldar, S. Zhang, Y. Xia, Y. Islam, B. Liu, S. Gervasio, F. L. Mulholland, A. J. Waller, Z. Wei, D. Haider, S. 2021-10-26 doi:10.1101/2021.10.26.465985 Cold Spring Harbor Laboratory Press 2021-10-26 <![CDATA[ Organization and composition of apicomplexan kinetochores reveals plasticity in chromosome segregation across parasite modes of division ]]> https://biorxiv.org/content/10.1101/2021.11.03.466924v1?rss=1 Brusini, L. Dos Santos Pacheco, N. Soldati-Favre, D. Brochet, M. 2021-11-03 doi:10.1101/2021.11.03.466924 Cold Spring Harbor Laboratory Press 2021-11-03 <![CDATA[ Genetic regulation of RNA splicing in human pancreatic islets ]]> https://biorxiv.org/content/10.1101/2021.11.11.468254v1?rss=1 Atla, G. Bonas-Guarch, S. Cuenca, M. Beucher, A. Garcia-Hurtado, J. Moran, I. Irimia, M. Prasad, R. B. Gloyn, A. L. Marselli, l. Suleiman, M. Berney, T. de Koning, E. J. P. Kerr-Conte, J. Pattou, F. Piemonti, L. Ferrer, J. 2021-11-13 doi:10.1101/2021.11.11.468254 Cold Spring Harbor Laboratory Press 2021-11-13 <![CDATA[ Oligogenic heterozygous inheritance of sperm abnormalities in mouse ]]> https://biorxiv.org/content/10.1101/2021.11.15.468601v1?rss=1 Martinez, G. Coutton, C. Loeuillet, C. Cazin, C. Muronova, J. Boguenet, M. Lambert, E. Dhellemmes, M. Chevalier, G. Hograindleur, J.-P. Vilpreux, C. Neirijnck, Y. Kherraf, Z. E. Escoffier, J. Nef, S. F. Ray, P. Arnoult, C. 2021-11-16 doi:10.1101/2021.11.15.468601 Cold Spring Harbor Laboratory Press 2021-11-16 <![CDATA[ Disruption of vacuolin microdomains in the host Dictyostelium discoideum increases resistance to Mycobacterium marinum-induced membrane damage and infection ]]> https://biorxiv.org/content/10.1101/2021.11.16.468763v1?rss=1 Bosmani, C. Perret, A. Leuba, F. Gueho, A. Hanna, N. Soldati, T. 2021-11-16 doi:10.1101/2021.11.16.468763 Cold Spring Harbor Laboratory Press 2021-11-16 <![CDATA[ Toxoplasma gondii phosphatidylserine flippase complex ATP2B-CDC50.4 critically participates in microneme exocytosis ]]> https://biorxiv.org/content/10.1101/2021.11.25.470034v1?rss=1 Bisio, H. Krishnan, A. Marq, J.-B. Soldati-Favre, D. 2021-11-25 doi:10.1101/2021.11.25.470034 Cold Spring Harbor Laboratory Press 2021-11-25 <![CDATA[ Transcriptional adaptation of sensory neurons to GPCR identity and activity ]]> https://biorxiv.org/content/10.1101/2021.11.29.468971v1?rss=1 Horgue, L. F. Assens, A. Fodoulian, L. Archinto, L. M. Tuberosa, J. Haider, A. Boillat, M. K. Carleton, A. Rodriguez, I. 2021-12-01 doi:10.1101/2021.11.29.468971 Cold Spring Harbor Laboratory Press 2021-12-01 <![CDATA[ Black-box testing in motor sequence learning ]]> https://biorxiv.org/content/10.1101/2021.12.01.470563v1?rss=1 Maceira-Elvira, P. Timmermann, J. E. Popa, T. Schmid, A.-C. Krakauer, J. W. Morishita, T. Wessel, M. J. Hummel, F. C. 2021-12-01 doi:10.1101/2021.12.01.470563 Cold Spring Harbor Laboratory Press 2021-12-01 <![CDATA[ Mitochondrial mutational spectrum is associated with mammalian longevity: a novel signature of oxidative damage. ]]> https://biorxiv.org/content/10.1101/2021.12.03.460832v1?rss=1 GH substitutions (H - heavy chain notation) is twice higher in species with high versus low generation length making their mtDNA more AH poor and GH rich. Considering that AH>GH substitutions are also sensitive to the time spent single stranded (TSSS) during asynchroniuos mtDNA replication we demonstrated that AH>GH substitution rate is a function of both species-specific generation length and position specific TSSS. We propose that AH>GH is a mitochondria-specific signature of oxidative damage associated with both aging and TSSS. ]]> Mikhailova, A. G. Mikhailova, A. A. Ushakova, K. Tretiakov, E. Shamanskiy, V. A. Iurchenko, A. Zazhytska, M. Kozenkova, E. Zdobnov, E. M. Makeev, V. Yurov, V. Tanaka, M. Gostimskaya, I. Fleischmann, Z. M. Annis, S. Franco, M. Wasko, K. Kunz, W. Knorre, D. Mazunin, I. Nikolaev, S. Fellay, J. Reymond, A. Khrapko, K. Gunbin, K. Popadin, K. 2021-12-07 doi:10.1101/2021.12.03.460832 Cold Spring Harbor Laboratory Press 2021-12-07 <![CDATA[ Transposable elements mediate genetic effects altering the expression of nearby genes in colorectal cancer ]]> https://biorxiv.org/content/10.1101/2021.12.03.471093v1?rss=1 Lykoskoufis, N. M. R. Planet, E. Ongen, H. Trono, D. Dermitzakis, E. T. 2021-12-04 doi:10.1101/2021.12.03.471093 Cold Spring Harbor Laboratory Press 2021-12-04 <![CDATA[ The need for unrealistic experiments in global change biology ]]> https://biorxiv.org/content/10.1101/2021.12.07.471575v1?rss=1 Collins, S. Thomas, M. K. 2021-12-10 doi:10.1101/2021.12.07.471575 Cold Spring Harbor Laboratory Press 2021-12-10 <![CDATA[ The UV RESISTANCE LOCUS 8-Mediated UV-B Response Is Required Alongside CRYPTOCHROME1 For Plant Survival Under Sunlight In The Field ]]> https://biorxiv.org/content/10.1101/2021.12.08.471623v1?rss=1 Stockenhuber, R. Akiyama, R. Tissot, N. Yamazaki, M. Wyler, M. Arongaus, A. B. Podolec, R. Sato, Y. Milosavljevic, S. Widmer, A. Ulm, R. Shimizu, K. K. 2021-12-09 doi:10.1101/2021.12.08.471623 Cold Spring Harbor Laboratory Press 2021-12-09 <![CDATA[ Disrupting inferior frontal cortex activity alters affect decoding efficiency from clear but not from ambiguous affective speech ]]> https://biorxiv.org/content/10.1101/2021.12.15.472758v1?rss=1 Ceravolo, L. Moisa, M. Grandjean, D. Ruff, C. Fruhholz, S. 2021-12-16 doi:10.1101/2021.12.15.472758 Cold Spring Harbor Laboratory Press 2021-12-16 <![CDATA[ A brain atlas of synapse protein lifetime across the mouse lifespan. ]]> https://biorxiv.org/content/10.1101/2021.12.16.472938v1?rss=1 Bulovaite, E. Qiu, Z. Kratschke, M. Zgraj, A. Fricker, D. Tuck, E. Gokhale, R. Jami, S. Merino-Serrais, P. Husi, E. O'Dell, T. J. DeFelipe, J. Komiyama, N. Holtmaat, A. Fransen, E. Grant, S. G. N. 2021-12-17 doi:10.1101/2021.12.16.472938 Cold Spring Harbor Laboratory Press 2021-12-17 <![CDATA[ From mass spectral features to molecules in molecular networks: a novel workflow for untargeted metabolomics. ]]> https://biorxiv.org/content/10.1101/2021.12.21.473622v1?rss=1 90% of the 156 molecules in the dataset. By focusing on actual molecules instead of ions, MolNotator greatly facilitates the selection of molecules of interest. O_FIG O_LINKSMALLFIG WIDTH=200 HEIGHT=126 SRC="FIGDIR/small/473622v1_ufig1.gif" ALT="Figure 1"> View larger version (29K): org.highwire.dtl.DTLVardef@730ecaorg.highwire.dtl.DTLVardef@1d012e1org.highwire.dtl.DTLVardef@187a1e5org.highwire.dtl.DTLVardef@195c53f_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Olivier-Jimenez, D. Bouchouireb, Z. Ollivier, S. Mocquard, J. Allard, P.-M. Bernadat, G. Chollet-Krugler, M. Rondeau, D. Boustie, J. van der Hooft, J. J. J. Wolfender, J.-L. 2021-12-22 doi:10.1101/2021.12.21.473622 Cold Spring Harbor Laboratory Press 2021-12-22 <![CDATA[ The transcription factor Zic4 acts as a transdifferentiation switch ]]> https://biorxiv.org/content/10.1101/2021.12.22.473838v1?rss=1 Vogg, M. C. Ferenc, J. Buzgariu, W. C. Perruchoud, C. Papasaikas, P. Sanchez, P. G. L. Nuninger, C. Delucinge-Vivier, C. Rampon, C. Beccari, L. Vriz, S. Vincent, S. Galliot, B. Tsiairis, C. 2021-12-23 doi:10.1101/2021.12.22.473838 Cold Spring Harbor Laboratory Press 2021-12-23 <![CDATA[ MEMO: Mass Spectrometry-based Sample Vectorization to Explore Chemodiverse Datasets ]]> https://biorxiv.org/content/10.1101/2021.12.24.474089v1?rss=1 View larger version (17K): org.highwire.dtl.DTLVardef@c540c0org.highwire.dtl.DTLVardef@1e07e7org.highwire.dtl.DTLVardef@198e030org.highwire.dtl.DTLVardef@1a6a15e_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Gaudry, A. Huber, F. Nothias, L.-F. Cretton, S. Kaiser, M. Wolfender, J.-L. Allard, P.-M. 2021-12-24 doi:10.1101/2021.12.24.474089 Cold Spring Harbor Laboratory Press 2021-12-24 <![CDATA[ CONTEXT-DEPENDENT ENHANCER FUNCTION REVEALED BYTARGETED INTER-TAD RELOCATION ]]> https://biorxiv.org/content/10.1101/2022.01.19.476888v1?rss=1 Bolt, C. C. Lopez-Delisle, L. Hintermann, A. Mascrez, B. Rauseo, A. Andrey, G. Duboule, D. 2022-01-21 doi:10.1101/2022.01.19.476888 Cold Spring Harbor Laboratory Press 2022-01-21 <![CDATA[ PP1 phosphatases control PAR-2 localization and polarity establishment in C. elegans embryos ]]> https://biorxiv.org/content/10.1101/2022.01.19.476913v1?rss=1 Calvi, I. Schwager, F. Gotta, M. 2022-01-20 doi:10.1101/2022.01.19.476913 Cold Spring Harbor Laboratory Press 2022-01-20 <![CDATA[ The small GTPase Arf1 regulates ATP synthesis and mitochondria homeostasis by modulating fatty acid metabolism ]]> https://biorxiv.org/content/10.1101/2022.01.26.477847v1?rss=1 Enkler, L. Pennauer, M. V. Szentgyörgyi, V. Prescianotto-Baschong, C. Riezman, I. Wiesyk, A. Kucharczyk, R. Spiess, M. Riezman, H. Spang, A. 2022-01-27 doi:10.1101/2022.01.26.477847 Cold Spring Harbor Laboratory Press 2022-01-27 <![CDATA[ Humans recognize affective cues in primate vocalizations: Acoustic and phylogenetic perspectives ]]> https://biorxiv.org/content/10.1101/2022.01.26.477864v1?rss=1 Debracque, C. Clay, Z. Gruber, T. Grandjean, D. 2022-01-27 doi:10.1101/2022.01.26.477864 Cold Spring Harbor Laboratory Press 2022-01-27 <![CDATA[ KaiC-like proteins improve stress resistance in environmental Pseudomonas species ]]> https://biorxiv.org/content/10.1101/2022.01.26.477890v1?rss=1 Terrettaz, C. Cabete, B. Geiser, J. Valentini, M. Gonzalez, D. 2022-01-27 doi:10.1101/2022.01.26.477890 Cold Spring Harbor Laboratory Press 2022-01-27 <![CDATA[ In silico analysis of the human milk oligosaccharide glycome reveals key enzymes of their biosynthesis ]]> https://biorxiv.org/content/10.1101/2022.01.27.477885v1?rss=1 McDonald, A. G. Mariethoz, J. Davey, G. P. Lisacek, F. 2022-01-28 doi:10.1101/2022.01.27.477885 Cold Spring Harbor Laboratory Press 2022-01-28 <![CDATA[ Categorization and discrimination of human and non-human primate affective vocalizations: investigation of the frontal cortex activity through fNIRS. ]]> https://biorxiv.org/content/10.1101/2022.01.29.478308v1?rss=1 Debracque, C. Ceravolo, L. Clay, Z. Grandjean, D. Gruber, T. 2022-01-29 doi:10.1101/2022.01.29.478308 Cold Spring Harbor Laboratory Press 2022-01-29 <![CDATA[ Fingerprinting of brain disease: Connectome identifiability in cognitive decline and neurodegeneration ]]> https://biorxiv.org/content/10.1101/2022.02.04.479112v1?rss=1 Stampacchia, S. Asadi, S. Tomczyk, S. Ribaldi, F. Scheffler, M. Lovblad, K.-O. Pievani, M. Frisoni, G. B. Garibotto, V. Amico, E. 2022-02-08 doi:10.1101/2022.02.04.479112 Cold Spring Harbor Laboratory Press 2022-02-08 <![CDATA[ Single-cell immune repertoire sequencing of B and T cells in murine models of infection and autoimmunity ]]> https://biorxiv.org/content/10.1101/2022.02.07.479381v1?rss=1 Shlesinger, D. Hong, K.-L. Shammas, G. Page, N. Sandu, I. Agrafiotis, A. Kreiner, V. Fonta, N. Vincenti, I. Wagner, I. Piccinno, M. Mariotte, A. Klimek, B. Dizerens, R. Manero-Carranza, M. Kuhn, R. Ehling, R. Frei, L. Khodaverdi, K. Panetti, C. Joller, N. Oxenius, A. Merkler, D. Reddy, S. T. Yermanos, A. 2022-02-10 doi:10.1101/2022.02.07.479381 Cold Spring Harbor Laboratory Press 2022-02-10 <![CDATA[ Cerebellar and cortico-striatal-midbrain contributions to reward-cognition processes and apathy within the psychosis continuum ]]> https://biorxiv.org/content/10.1101/2022.02.09.479617v1?rss=1 Begue, I. Brakowski, J. Seifritz, E. Dagher, A. Tobler, P. N. Kirschner, M. Kaiser, S. 2022-02-10 doi:10.1101/2022.02.09.479617 Cold Spring Harbor Laboratory Press 2022-02-10 <![CDATA[ Brain aging differs with cognitive ability regardless of education ]]> https://biorxiv.org/content/10.1101/2022.02.09.479697v1?rss=1 Walhovd, K. B. Nyberg, L. Lindenberger, U. Magnussen, F. Amlien, I. K. Sorensen, O. Wang, Y. Mowinckel, A. M. Kievit, R. Ebmeier, K. P. Bartres-Faz, D. Kuhn, S. Boraxbekk, C.-J. Ghisletta, P. Madsen, K. S. Baare, W. Zsoldos, E. Penninx, B. Fjell, A. 2022-02-10 doi:10.1101/2022.02.09.479697 Cold Spring Harbor Laboratory Press 2022-02-10 <![CDATA[ NICEgame: A workflow for annotating the knowledge gaps in metabolic reconstructions, using known and hypothetical reactions ]]> https://biorxiv.org/content/10.1101/2022.02.10.479881v1?rss=1 Vayena, e. Chiappino-Pepe, A. MohammadiPeyhani, H. Francioli, Y. Hadadi, N. Ataman, M. Hafner, J. Pavlou, S. Hatzimanikatis, V. 2022-02-10 doi:10.1101/2022.02.10.479881 Cold Spring Harbor Laboratory Press 2022-02-10 <![CDATA[ Structural basis of human IL-18 sequestration by the decoy receptor IL-18 binding protein (IL-18BP) in inflammation and tumor immunity ]]> https://biorxiv.org/content/10.1101/2022.02.10.479912v1?rss=1 Detry, S. Andries, J. Bloch, Y. Gabay, C. Clancy, D. Savvides, S. N. 2022-02-10 doi:10.1101/2022.02.10.479912 Cold Spring Harbor Laboratory Press 2022-02-10 <![CDATA[ Spindle reorientation in response to mechanical stress is an emergent property of the spindle positioning mechanisms ]]> https://biorxiv.org/content/10.1101/2022.02.13.480269v1?rss=1 Kelkar, M. Bohec, P. Smith, M. Sreenivasan, V. Lisica, A. Valon, L. Ferber, E. Baum, B. Salbreux, G. Charras, G. 2022-02-14 doi:10.1101/2022.02.13.480269 Cold Spring Harbor Laboratory Press 2022-02-14 <![CDATA[ Optical Control of Membrane Fluidity Modulates Protein Secretion ]]> https://biorxiv.org/content/10.1101/2022.02.14.480333v1?rss=1 Jimenez-Rojo, N. Feng, S. Morstein, J. Pritzl, S. D. Harayama, T. Asaro, A. Veprek, N. A. Arp, C. J. Reynders, M. Novak, A. J. E. Kanshin, E. Ueberheide, B. Lohmuller, T. Riezman, H. Trauner, D. 2022-02-14 doi:10.1101/2022.02.14.480333 Cold Spring Harbor Laboratory Press 2022-02-14 <![CDATA[ Vps60 initiates formation of alternative membrane-bound ESCRT-III filaments ]]> https://biorxiv.org/content/10.1101/2022.02.16.480668v1?rss=1 Pfitzner, A.-K. Zivkovic, H. humbert, f. Roux, A. 2022-02-18 doi:10.1101/2022.02.16.480668 Cold Spring Harbor Laboratory Press 2022-02-18 <![CDATA[ Antisense non-coding transcription represses the PHO5 model gene via remodelling of promoter chromatin structure ]]> https://biorxiv.org/content/10.1101/2022.02.21.481265v1?rss=1 Novacic, A. Menendez, D. Ljubas, J. Barbaric, S. Stutz, F. Soudet, J. Stuparevic, I. 2022-02-21 doi:10.1101/2022.02.21.481265 Cold Spring Harbor Laboratory Press 2022-02-21 <![CDATA[ A Neural Model of Task Compositionality with Natural Language Instructions ]]> https://biorxiv.org/content/10.1101/2022.02.22.481293v1?rss=1 Riveland, R. Pouget, A. 2022-02-24 doi:10.1101/2022.02.22.481293 Cold Spring Harbor Laboratory Press 2022-02-24 <![CDATA[ Complex effects of chytrid parasites on the growth of the cyanobacterium Planktothrix rubescens across interacting temperature and light gradients ]]> https://biorxiv.org/content/10.1101/2022.02.24.481659v1?rss=1 Wierenga, J. Thomas, M. K. Ranjan, R. Ibelings, B. W. 2022-02-24 doi:10.1101/2022.02.24.481659 Cold Spring Harbor Laboratory Press 2022-02-24 <![CDATA[ Salient 40 Hz sounds probe affective aversion and neural excitability ]]> https://biorxiv.org/content/10.1101/2022.02.26.482077v1?rss=1 Schneefeld, F. Doelling, K. D. Marchesotti, S. Schwartz, S. Igloi, K. Giraud, A.-L. Arnal, L. H. 2022-03-01 doi:10.1101/2022.02.26.482077 Cold Spring Harbor Laboratory Press 2022-03-01 <![CDATA[ Functional characterization of the thrombospondin-related paralogous proteins rhoptry discharge factor 1 and 2 unveils phenotypic plasticity in Toxoplasma gondii rhoptry exocytosis ]]> https://biorxiv.org/content/10.1101/2022.03.02.482699v1?rss=1 Possenti, A. Di Cristina, M. Nicastro, C. Lunghi, M. Messina, V. Piro, F. Tramontana, L. Cherchi, S. Falchi, M. Bertuccini, L. Spano, F. 2022-03-02 doi:10.1101/2022.03.02.482699 Cold Spring Harbor Laboratory Press 2022-03-02 <![CDATA[ Cardio-audio synchronization elicits prediction in auditory sequences during human wakefulness and sleep ]]> https://biorxiv.org/content/10.1101/2022.03.03.482861v1?rss=1 Pelentritou, A. Pfeiffer, C. Schwartz, S. De Lucia, M. 2022-03-04 doi:10.1101/2022.03.03.482861 Cold Spring Harbor Laboratory Press 2022-03-04 <![CDATA[ Interpreting dynamics of neural activity after dimensionality reduction ]]> https://biorxiv.org/content/10.1101/2022.03.04.482986v1?rss=1 Proix, T. Perich, M. G. Milekovic, T. 2022-03-07 doi:10.1101/2022.03.04.482986 Cold Spring Harbor Laboratory Press 2022-03-07 <![CDATA[ Geneticin shows selective antiviral activity against SARS-CoV-2 by targeting programmed -1 ribosomal frameshifting ]]> https://biorxiv.org/content/10.1101/2022.03.08.483429v1?rss=1 Varricchio, C. Mathez, G. Kaiser, L. Tapparel, C. Brancale, A. Cagno, V. 2022-03-08 doi:10.1101/2022.03.08.483429 Cold Spring Harbor Laboratory Press 2022-03-08 <![CDATA[ Efficacy and safety of a patch containing adipose-derived stem cells for skin wound healing. Results form a comprehensive pre-clinical evaluation program ]]> https://biorxiv.org/content/10.1101/2022.03.09.483580v1?rss=1 Brembilla, N. Modarressi, A. Andre Levigne, D. Brioudes, E. Lanza, F. Vuagnat, H. Durual, S. Marger, L. Boehncke, W.-H. Krause, K.-H. Preynat-Seauve, O. 2022-03-11 doi:10.1101/2022.03.09.483580 Cold Spring Harbor Laboratory Press 2022-03-11 <![CDATA[ Structure and regulation of the Myotonic dystrophy kinase-Related Cdc42-binding Kinase ]]> https://biorxiv.org/content/10.1101/2022.03.11.483953v1?rss=1 Truebestein, L. Waltenberger, E. Gehin, C. Gavin, A.-C. Leonard, T. A. 2022-03-11 doi:10.1101/2022.03.11.483953 Cold Spring Harbor Laboratory Press 2022-03-11 <![CDATA[ Not1 and Not4 inversely determine mRNA solubility that sets the dynamics of co-translational events ]]> https://biorxiv.org/content/10.1101/2022.03.14.484207v1?rss=1 Allen, G. Weiss, B. Panasenko, O. O. Huch, S. Villanyi, Z. Albert, B. Dilg, D. Zagatti, M. Schaughency, P. Liao, S. Corden, J. Polte, C. Shore, D. Ignatova, Z. Pelechano, V. Collart, M. A. 2022-03-14 doi:10.1101/2022.03.14.484207 Cold Spring Harbor Laboratory Press 2022-03-14 <![CDATA[ Phase separated ribosome nascent chain complexes paused in translation are capable to continue expression of proteins playing role in genotoxic stress response upon DNA damage ]]> https://biorxiv.org/content/10.1101/2022.03.16.484567v1?rss=1 Nemeth-Szatmari, O. Gyorkei, A. Varga, D. H.Kovacs, B. B. Igaz, N. Nemet, K. Bagi, N. Nagy-Miko, B. Balogh, D. Razga, Z. Erdelyi, M. Papp, B. Kiricsi, M. Blastyak, A. Collart, M. M. Boros, I. Villanyi, Z. 2022-03-16 doi:10.1101/2022.03.16.484567 Cold Spring Harbor Laboratory Press 2022-03-16 <![CDATA[ Structural and functional insight into the plant unique multimodular triphosphosphate tunnel metalloenzymes of Arabidopsis thaliana ]]> https://biorxiv.org/content/10.1101/2022.03.18.484887v1?rss=1 Pesquera, M. Martinez, J. Wang, K. Hofmann, M. Loubery, S. Steensma, P. Hothorn, M. Fitzpatrick, T. B. 2022-03-19 doi:10.1101/2022.03.18.484887 Cold Spring Harbor Laboratory Press 2022-03-19 <![CDATA[ Interacting active surfaces: a model for three-dimensional cell aggregates ]]> https://biorxiv.org/content/10.1101/2022.03.21.484343v1?rss=1 Torres-Sanchez, A. Winter, M. K. Salbreux, G. 2022-03-22 doi:10.1101/2022.03.21.484343 Cold Spring Harbor Laboratory Press 2022-03-22 <![CDATA[ Temporal dynamics of cognitive flexibility in adolescents with anorexia nervosa: a high density EEG study ]]> https://biorxiv.org/content/10.1101/2022.03.24.485666v1?rss=1 Berchio, C. Annen, L. C. Bouamoud, Y. Micali, N. 2022-03-27 doi:10.1101/2022.03.24.485666 Cold Spring Harbor Laboratory Press 2022-03-27 <![CDATA[ Genetic glyco-profiling and rewiring of insulated flagellin glycosylation pathways ]]> https://biorxiv.org/content/10.1101/2022.03.25.485807v1?rss=1 Kint, N. Dubois, T. Viollier, P. H. 2022-03-26 doi:10.1101/2022.03.25.485807 Cold Spring Harbor Laboratory Press 2022-03-26 <![CDATA[ Structure of the connexin-43 gap junction channel reveals a closed sieve-like molecular gate ]]> https://biorxiv.org/content/10.1101/2022.03.26.485947v1?rss=1 Qi, C. Acosta-Gutierrez, S. Lavriha, P. Othman, A. Lopez-Pigozzi, D. Bayraktar, E. Schuster, D. Picotti, P. Zamboni, N. Bortolozzi, M. Gervasio, F. L. Korkhov, V. M. 2022-03-27 doi:10.1101/2022.03.26.485947 Cold Spring Harbor Laboratory Press 2022-03-27 <![CDATA[ Rhythmic modulation of prediction errors: a possible role for the beta-range in speech processing ]]> https://biorxiv.org/content/10.1101/2022.03.28.486037v1?rss=1 Hovsepyan, S. Olasagasti, I. Giraud, A.-L. 2022-03-29 doi:10.1101/2022.03.28.486037 Cold Spring Harbor Laboratory Press 2022-03-29 <![CDATA[ Recurrent but short-lived duplications of centromeric proteins in holocentric Caenorhabditis species ]]> https://biorxiv.org/content/10.1101/2022.03.31.486469v1?rss=1 Caro, L. Raman, P. Steiner, F. A. Ailion, M. Malik, H. S. 2022-03-31 doi:10.1101/2022.03.31.486469 Cold Spring Harbor Laboratory Press 2022-03-31 <![CDATA[ A deep hierarchy of predictions enables assignment of semantic roles in real-time speech comprehension ]]> https://biorxiv.org/content/10.1101/2022.04.01.486694v1?rss=1 Su, Y. Olasagasti, I. Giraud, A.-L. 2022-04-05 doi:10.1101/2022.04.01.486694 Cold Spring Harbor Laboratory Press 2022-04-05 <![CDATA[ Temperature and resources interact to shape phytoplankton size-abundance relationships at a continental scale ]]> https://biorxiv.org/content/10.1101/2022.04.09.487731v1?rss=1 Gjoni, V. Glazier, D. S. Ibelings, B. W. Thomas, M. K. 2022-04-10 doi:10.1101/2022.04.09.487731 Cold Spring Harbor Laboratory Press 2022-04-10 <![CDATA[ The Interplay of Attention and Conscious Perception: Evidence from Human Intracerebral Recordings and Computational Modeling ]]> https://biorxiv.org/content/10.1101/2022.04.10.487690v1?rss=1 Liu, J. Bayle, D. J. Spagna, A. Sitt, J. D. Bourgeois, A. Lehongre, K. Fernandez-Vidal, S. Navarro, V. Adam, C. Lambrecq, V. Malkinson, T. S. Bartolomeo, P. 2022-04-11 doi:10.1101/2022.04.10.487690 Cold Spring Harbor Laboratory Press 2022-04-11 <![CDATA[ The SNARE Sec22b regulates phagosome maturation by promoting ORP8-mediated PI(4)P exchange at ER-phagosome contact sites. ]]> https://biorxiv.org/content/10.1101/2022.04.12.487993v1?rss=1 Criado Santos, N. Bouvet, S. Bermont, F. Castelbou, C. Mansour, F. Azam, M. Giordano, F. Nunes-Hasler, P. 2022-04-12 doi:10.1101/2022.04.12.487993 Cold Spring Harbor Laboratory Press 2022-04-12 <![CDATA[ Supramolecular architecture of the ER-mitochondria encounter structure in its native environment ]]> https://biorxiv.org/content/10.1101/2022.04.12.488000v1?rss=1 Wozny, M. R. Di Luca, A. Morado, D. R. Picco, A. Hoffmann, P. C. Miller, E. A. Vanni, S. Kukulski, W. 2022-04-12 doi:10.1101/2022.04.12.488000 Cold Spring Harbor Laboratory Press 2022-04-12 <![CDATA[ Identification of two bZIP transcription factors that regulate development of pavement and trichome cells in Arabidopsis thaliana by single-cell RNA-sequencing ]]> https://biorxiv.org/content/10.1101/2022.04.12.488054v1?rss=1 Wu, R. Liu, Z. Wang, J. Li, W. Qin, A. Yu, X. Liu, H. Guo, C. Zhao, Z. Zhang, Y. Zhou, Y. Sun, S. Liu, Y. Hu, M. Yang, J. Jan, M. Bawa, G. Rochaix, J.-D. An, G. Y. Herrera-Estrella, L. Tran, L.-S. P. Sun, X. 2022-04-13 doi:10.1101/2022.04.12.488054 Cold Spring Harbor Laboratory Press 2022-04-13 <![CDATA[ This is GlycoQL ]]> https://biorxiv.org/content/10.1101/2022.04.14.488348v1?rss=1 Hayes, C. Daponte, V. Mariethoz, J. LISACEK, F. 2022-04-14 doi:10.1101/2022.04.14.488348 Cold Spring Harbor Laboratory Press 2022-04-14 <![CDATA[ C/EBPα confers dependence to fatty acid anabolic pathways and vulnerability to lipid oxidative stress in FLT3-mutant leukemia ]]> https://biorxiv.org/content/10.1101/2022.04.15.488522v1?rss=1 Sabatier, M. Birsen, R. Tamburini, J. Sarry, J.-E. 2022-04-16 doi:10.1101/2022.04.15.488522 Cold Spring Harbor Laboratory Press 2022-04-16 <![CDATA[ Cerebral activity in monkeys Papio anubis during the perception of conspecific and heterospecific agonistic vocalizations: A functional Near Infrared Spectroscopy study ]]> https://biorxiv.org/content/10.1101/2022.04.21.489037v1?rss=1 Debracque, C. Gruber, T. Lacoste, R. Meguerditchian, A. Grandjean, D. 2022-04-22 doi:10.1101/2022.04.21.489037 Cold Spring Harbor Laboratory Press 2022-04-22 <![CDATA[ Preterm infants voice processing is mediated by voice familiarity ]]> https://biorxiv.org/content/10.1101/2022.04.26.489394v1?rss=1 preterms for the naturalistic mothers voice is evident in the theta frequency band in the left temporal area, where only full-term newborns showed an increased activity for the mothers voice, whereas preterm infants showed significant activation for stranger naturalistic speech. Similarly, a significant group contrast in the low and high theta in the right temporal regions indicates higher activations for the strangers speech in preterms. Finally, only full-term newborns presented a late gamma band increase for the maternal naturalistic speech, indicating a more mature brain response. The current study based on neural time-frequency patterns, demonstrates that preterm infants lack selective brain responses to mothers naturalistic voice typical for full-term newborns, whereas preterms are selectively responsive to stranger voices in both temporal hemispheres. ]]> Filippa, M. Benis, D. Adam-Darque, A. Huppi, P. S. Grandjean, D. 2022-04-26 doi:10.1101/2022.04.26.489394 Cold Spring Harbor Laboratory Press 2022-04-26 <![CDATA[ Hunter-gatherer oral microbiomes are shaped by contact network structure ]]> https://biorxiv.org/content/10.1101/2022.05.03.489993v1?rss=1 Musciotto, F. Dobon, B. Greenacre, M. Mira, A. Page, A. E. Dyble, M. Viguier, S. Smith, D. Chaudhary, N. Salali, G. D. Gerbault, P. Schlaepfer, R. Astete, L. H. Ngales, M. Gomez-Gardenes, J. Latora, V. Battiston, F. Bertranpetit, J. Vinicius, L. Migliano, A. B. 2022-05-03 doi:10.1101/2022.05.03.489993 Cold Spring Harbor Laboratory Press 2022-05-03 <![CDATA[ Extrinsic regulation of interneuron specification and migration ]]> https://biorxiv.org/content/10.1101/2022.05.03.490384v1?rss=1 Pipicelli, F. Baumann, N. Di Giaimo, R. Kyrousi, C. Bonrath, R. Jabaudon, D. Cappello, S. 2022-05-04 doi:10.1101/2022.05.03.490384 Cold Spring Harbor Laboratory Press 2022-05-04 <![CDATA[ The effect of motor-induced shaft dynamics on microtubule stability and length ]]> https://biorxiv.org/content/10.1101/2022.05.04.490659v1?rss=1 Schaer, J. Andreu-Carbo, M. Kruse, K. Aumeier, C. 2022-05-05 doi:10.1101/2022.05.04.490659 Cold Spring Harbor Laboratory Press 2022-05-05 <![CDATA[ Reproducibility of in-vivo electrophysiological measurements in mice ]]> https://biorxiv.org/content/10.1101/2022.05.09.491042v1?rss=1 The International Brain Laboratory, Banga, K. Benson, J. Bonacchi, N. Bruijns, S. A. Campbell, R. Chapuis, G. A. Churchland, A. K. Davatolhagh, M. F. Lee, H. D. Faulkner, M. Steinmetz, N. A. Paninski, L. Taheri, M. Roth, N. 2022-05-09 doi:10.1101/2022.05.09.491042 Cold Spring Harbor Laboratory Press 2022-05-09 <![CDATA[ The evolution of information transmission in mammalian brain networks ]]> https://biorxiv.org/content/10.1101/2022.05.09.491115v1?rss=1 Griffa, A. Mach, M. Dedelley, J. Gutierrez-Barragan, D. Gozzi, A. Allali, G. Grandjean, J. Van De Ville, D. Amico, E. 2022-05-10 doi:10.1101/2022.05.09.491115 Cold Spring Harbor Laboratory Press 2022-05-10 <![CDATA[ Mechanochemical rules for membrane-reshaping composite filaments ]]> https://biorxiv.org/content/10.1101/2022.05.10.490642v1?rss=1 Meadowcroft, B. Palaia, I. Pfitzner, A.-K. Roux, A. Baum, B. Saric, A. 2022-05-10 doi:10.1101/2022.05.10.490642 Cold Spring Harbor Laboratory Press 2022-05-10 <![CDATA[ Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases ]]> https://biorxiv.org/content/10.1101/2022.05.11.491453v1?rss=1 Nutma, E. Fancy, N. Weinert, M. Marzin, M. C. Tsartsalis, S. Muirhead, R. C. Falk, I. de Bruin, J. Hollaus, D. Pieterman, R. Anink, J. Story, D. Chandran, S. Tang, J. Trolese, M. C. Saito, T. Saido, T. C. Wiltshire, K. Beltran-Lobo, P. Philips, A. Antel, J. Healy, L. Moore, C. S. Bendotti, C. Aronica, E. Radulescu, C. I. Barnes, S. J. Hampton, D. W. van der Valk, P. Jacobson, S. Matthews, P. M. Amor, S. Owen, D. R. 2022-05-11 doi:10.1101/2022.05.11.491453 Cold Spring Harbor Laboratory Press 2022-05-11 <![CDATA[ Open Access Repository-Scale Propagated Nearest Neighbor Suspect Spectral Library for Untargeted Metabolomics ]]> https://biorxiv.org/content/10.1101/2022.05.15.490691v1?rss=1 Bittremieux, W. Avalon, N. E. Thomas, S. P. Kakhkhorov, S. A. Aksenov, A. A. Portal Gomes, P. W. Aceves, C. M. Caraballo Rodriguez, A. M. Gauglitz, J. M. Gerwick, W. H. Jarmusch, A. K. Kaddurah-Daouk, R. F. Kang, K. B. Kim, H. W. Kondic, T. Mannochio-Russo, H. Meehan, M. J. Melnik, A. Nothias, L.-F. O'Donovan, C. Panitchpakdi, M. Petras, D. Schmid, R. Schymanski, E. L. van der Hooft, J. J. J. Weldon, K. C. Yang, H. Zemlin, J. Wang, M. Dorrestein, P. C. 2022-05-15 doi:10.1101/2022.05.15.490691 Cold Spring Harbor Laboratory Press 2022-05-15 <![CDATA[ Ultrastructure Expansion Microscopy reveals the nanoscale cellular architecture of budding and fission yeast ]]> https://biorxiv.org/content/10.1101/2022.05.16.492060v1?rss=1 Hinterndorfer, K. Laporte, M. H. Mikus, F. Petrozzi, L. T. Bourgoint, C. Prouteau, M. Dey, G. Loewith, R. Guichard, P. Hamel, V. 2022-05-16 doi:10.1101/2022.05.16.492060 Cold Spring Harbor Laboratory Press 2022-05-16 <![CDATA[ Single cell analysis of the dorsal V-SVZ reveals differential quiescence of postnatal pallial and subpallial neural stem cells driven by TGFbeta/BMP-signalling ]]> https://biorxiv.org/content/10.1101/2022.05.20.492790v1?rss=1 Marcy, G. Foucault, L. Babina, E. Texeraud, E. Zweifel, S. Heinrich, C. Parras, C. Vargas-Hernandez, H. Jabaudon, D. Raineteau, O. 2022-05-20 doi:10.1101/2022.05.20.492790 Cold Spring Harbor Laboratory Press 2022-05-20 <![CDATA[ Revealing druggable cryptic pockets in the Nsp-1 of SARS-CoV-2 and other β-coronaviruses by simulations and crystallography ]]> https://biorxiv.org/content/10.1101/2022.05.20.492819v1?rss=1 Borsatto, A. Galdadas, I. Gervasio, F. L. Estarellas, C. Haider, S. Kozielski, F. Damfo, S. Ma, S. 2022-05-20 doi:10.1101/2022.05.20.492819 Cold Spring Harbor Laboratory Press 2022-05-20 <![CDATA[ Spatial encoding of forelimb proprioception in the mouse somatosensory cortex ]]> https://biorxiv.org/content/10.1101/2022.05.25.493376v1?rss=1 Alonso, I. Palacio-Manzano, M. Scheer, I. Philippides, A. Prsa, M. 2022-05-25 doi:10.1101/2022.05.25.493376 Cold Spring Harbor Laboratory Press 2022-05-25 <![CDATA[ Ubx5-Cdc48 assists the protease Wss1 at DNA-protein crosslink sites in yeast ]]> https://biorxiv.org/content/10.1101/2022.05.30.493988v1?rss=1 Noireterre, A. Bagdiul, I. Serbyn, N. Stutz, F. 2022-05-30 doi:10.1101/2022.05.30.493988 Cold Spring Harbor Laboratory Press 2022-05-30 <![CDATA[ Mitochondrial pyruvate metabolism regulates the activation of quiescent adult neural stem cells ]]> https://biorxiv.org/content/10.1101/2022.05.31.494137v1?rss=1 View larger version (41K): org.highwire.dtl.DTLVardef@1ee8788org.highwire.dtl.DTLVardef@1040633org.highwire.dtl.DTLVardef@1330d26org.highwire.dtl.DTLVardef@a474e0_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Petrelli, F. Scandella, V. Montessuit, S. Zamboni, N. Martinou, J.-C. Knobloch, M. 2022-05-31 doi:10.1101/2022.05.31.494137 Cold Spring Harbor Laboratory Press 2022-05-31 <![CDATA[ Plasmacytoid dendritic cells regulate megakaryocyte and platelet homeostasis ]]> https://biorxiv.org/content/10.1101/2022.05.31.494147v1?rss=1 Gaertner, F. Ishikawa-Ankerhold, H. Stutte, S. Fu, W. Guo, C. Weitz, J. Dueck, A. Zhang, Z. van den Heuvel, D. Fumagalli, V. Lorenz, M. von Baumgarten, L. Stark, K. Straub, T. von Stillfried, S. Boor, P. Colonna, M. Schulz, C. Brocker, T. Walzog, B. Scheiermann, C. Engelhardt, S. Aird, W. C. Petzold, T. Sixt, M. Rudelius, M. Nerlov, C. Iannacone, M. Oostendorp, R. A. J. Massberg, S. 2022-06-01 doi:10.1101/2022.05.31.494147 Cold Spring Harbor Laboratory Press 2022-06-01 <![CDATA[ Claudin-4, a core component of the tight-junctional complex along the collecting system, is induced in nephrotic syndrome ]]> https://biorxiv.org/content/10.1101/2022.06.01.494142v1?rss=1 Olivier, V. SASSI, A. Arnoux, G. Chambrey, R. Monnay, I. Chassot, A. Udwan, K. Dizin, E. Rutkowski, J. M. Cheval, L. Crambert, G. Wagner, C. A. Doucet, A. Eladari, D. Moll, S. Feraille, E. K Ramakrishnan, S. 2022-06-01 doi:10.1101/2022.06.01.494142 Cold Spring Harbor Laboratory Press 2022-06-01 <![CDATA[ CRISPR/Cas9 screen reveals a role of purine synthesis for estrogen receptor α activity and tamoxifen resistance of breast cancer cells ]]> https://biorxiv.org/content/10.1101/2022.06.03.494664v1?rss=1 Hany, D. Vafeiadou, V. Picard, D. 2022-06-03 doi:10.1101/2022.06.03.494664 Cold Spring Harbor Laboratory Press 2022-06-03 <![CDATA[ Conoid extrusion serves as gatekeeper for entry of glideosome components into the pellicular space to control motility and invasion in Apicomplexa ]]> https://biorxiv.org/content/10.1101/2022.06.06.494926v1?rss=1 Dos Santos Pacheco, N. Brusini, L. Haase, R. Tosetti, N. Maco, B. Brochet, M. Vadas, O. Soldati-Favre, D. 2022-06-06 doi:10.1101/2022.06.06.494926 Cold Spring Harbor Laboratory Press 2022-06-06 <![CDATA[ A cellular assay for spike/ACE2 fusion: quantification of fusion-inhibitory antibodies after COVID-19 and vaccination ]]> https://biorxiv.org/content/10.1101/2022.06.09.495433v1?rss=1 Abdul, F. Ribaux, P. Caillon, A. Malezieux, A. Prendki, V. Zhukovsky, N. Delhaes, F. Krause, K.-H. Preynat-Seauve, O. 2022-06-09 doi:10.1101/2022.06.09.495433 Cold Spring Harbor Laboratory Press 2022-06-09 <![CDATA[ Cognitive exertion affects the appraisal of one's own and other people's pain ]]> https://biorxiv.org/content/10.1101/2022.06.09.495450v1?rss=1 Riontino, L. Fournier, R. Lapteva, A. Silvestrini, N. Schwartz, S. Corradi-Dell'Acqua, C. 2022-06-12 doi:10.1101/2022.06.09.495450 Cold Spring Harbor Laboratory Press 2022-06-12 <![CDATA[ Molecular phenotyping of colorectal neoplasia shows dynamic and adaptive cancer stem cell population admixture ]]> https://biorxiv.org/content/10.1101/2022.06.11.495729v1?rss=1 Gil Vasquez, E. Nasreddin, N. Valbuena, G. N. Mulholland, E. J. Belnoue-Davis, H. L. Eggington, H. Schenck, R. O. Wouters, V. M. Wirapati, P. Gilroy, K. Lannagan, T. R. M. Flanagan, D. J. Najumudeen, A. K. Omwenga, S. McCorry, A. M. B. Easton, A. Koelzer, V. H. East, J. E. Morton, D. Trusolino, L. Maughan, T. Campbell, A. D. Loughrey, M. B. Dunne, P. D. Tsantoulis, P. Huels, D. J. Tejpar, S. Sansom, O. Leedham, S. J. 2022-06-12 doi:10.1101/2022.06.11.495729 Cold Spring Harbor Laboratory Press 2022-06-12 <![CDATA[ The Arabidopsis endosperm is a temperature-sensing tissue that implements seed thermoinhibition through phyB and PIF3 ]]> https://biorxiv.org/content/10.1101/2022.06.13.495921v1?rss=1 Piskurewicz, U. Sentandreu, M. Glauser, G. Lopez-Molina, L. 2022-06-13 doi:10.1101/2022.06.13.495921 Cold Spring Harbor Laboratory Press 2022-06-13 <![CDATA[ Increased severity of chronic kidney disease in response to high potassium intake is dependent on mineralocorticoid receptor activation ]]> https://biorxiv.org/content/10.1101/2022.06.15.496280v1?rss=1 Olivier, V. Arnoux, G. Ramakrishnan, S. SASSI, A. Roth, I. Chassot, A. Tournier, M. Dizin, E. Hummler, E. Rutkowski, J. Feraille, E. 2022-06-17 doi:10.1101/2022.06.15.496280 Cold Spring Harbor Laboratory Press 2022-06-17 <![CDATA[ Isolation of a novel heterodimeric PSII complex via strep-tagged PsbO ]]> https://biorxiv.org/content/10.1101/2022.06.15.496312v1?rss=1 Lambertz, J. Meier-Credo, J. Kucher, S. Bordignon, E. Langer, J. D. Nowaczyk, M. M. 2022-06-16 doi:10.1101/2022.06.15.496312 Cold Spring Harbor Laboratory Press 2022-06-16 <![CDATA[ Human concurrent intracranial EEG and fMRI reveals multiple temporally independent but spatially similar connectome trajectories across timescales ]]> https://biorxiv.org/content/10.1101/2022.06.17.496647v1?rss=1 Mostame, P. Wirsich, J. Alderson, T. H. Ridley, B. Carmichael, D. Vulliemoz, S. Guye, M. Lemieux, L. Sadaghiani, S. 2022-06-20 doi:10.1101/2022.06.17.496647 Cold Spring Harbor Laboratory Press 2022-06-20 <![CDATA[ Distraction and cognitive control independently impact parietal and prefrontal neural response to pain ]]> https://biorxiv.org/content/10.1101/2022.06.20.496774v1?rss=1 Silvestrini, N. Corradi-Dell'Acqua, C. 2022-06-21 doi:10.1101/2022.06.20.496774 Cold Spring Harbor Laboratory Press 2022-06-21 <![CDATA[ Clock and riboswitch control of THIC in tandem are essential for appropriate gauging of TDP levels under light/dark cycles in Arabidopsis ]]> https://biorxiv.org/content/10.1101/2022.06.20.496815v1?rss=1 Noordally, Z. Land, L. Trichtinger, C. Dalvit, I. de Meyer, M. Wang, K. Fitzpatrick, T. B. 2022-06-20 doi:10.1101/2022.06.20.496815 Cold Spring Harbor Laboratory Press 2022-06-20 <![CDATA[ A fluorescent perilipin 2 knock-in mouse model visualizes lipid droplets in the developing and adult brain ]]> https://biorxiv.org/content/10.1101/2022.06.21.496932v1?rss=1 Madsen, S. Delgado, A. C. Cadilhac, C. Battison, F. Maillard, V. Magrinelli, E. Jabaudon, D. Telley, L. Doetsch, F. Knobloch, M. 2022-06-21 doi:10.1101/2022.06.21.496932 Cold Spring Harbor Laboratory Press 2022-06-21 <![CDATA[ Reinstatement of emotional associations during human sleep: an intracranial EEG study ]]> https://biorxiv.org/content/10.1101/2022.06.24.497499v1?rss=1 Legendre, G. Y. T. Bayer, L. Seeck, M. Spinelli, L. Schwartz, S. Sterpenich, V. 2022-06-28 doi:10.1101/2022.06.24.497499 Cold Spring Harbor Laboratory Press 2022-06-28 <![CDATA[ Between fishing and farming: palaeogenomic analyses reveal cross-cultural interactions triggered by the arrival of the Neolithic in the Danube Gorges ]]> https://biorxiv.org/content/10.1101/2022.06.24.497512v1?rss=1 Hofmanova, Z. Reyna-Blanco, C. S. de Becdelievre, C. Schulz, I. Bloecher, J. Jovanovic, J. Winkelbach, L. Figarska, S. M. Schulz, A. Porcic, M. Kvetina, P. Tsoupas, A. Currat, M. Buzhilova, A. Gerritsen, F. Karul, N. McGlynn, G. Orschiedt, J. Oezbal, R. Peters, J. Ridush, B. Terberger, T. Teschler-Nicola, M. Zarina, G. Zeeb-Lanz, A. Stefanovic, S. Burger, J. Wegmann, D. 2022-06-28 doi:10.1101/2022.06.24.497512 Cold Spring Harbor Laboratory Press 2022-06-28 <![CDATA[ Trapping virus-loaded aerosols using granular protein nanofibrils and iron oxyhydroxides nanoparticles ]]> https://biorxiv.org/content/10.1101/2022.06.29.498082v1?rss=1 Armanious, A. Wang, H. Alpert, P. Medaglia, C. Peydayesh, M. Zwygart, A. C.-A. Gübeli, C. Handschin, S. Bolisetty, S. Ammann, M. Tapparel, C. Stellacci, F. Mezzenga, R. 2022-06-30 doi:10.1101/2022.06.29.498082 Cold Spring Harbor Laboratory Press 2022-06-30 <![CDATA[ Architecture of the MKK6-p38α complex defines the basis of MAPK specificity and activation ]]> https://biorxiv.org/content/10.1101/2022.07.04.498667v1?rss=1 Juyoux, P. Galdadas, I. Gobbo, D. Tully, M. Gervasio, F. L. Pellegrini, E. Bowler, M. W. 2022-07-04 doi:10.1101/2022.07.04.498667 Cold Spring Harbor Laboratory Press 2022-07-04 <![CDATA[ The Bioregistry: Unifying the Identification of Biomedical Entities through an Integrative, Open, Community-driven Metaregistry ]]> https://biorxiv.org/content/10.1101/2022.07.08.499378v1?rss=1 Hoyt, C. T. Balk, M. Callahan, T. J. Domingo-Fernandez, D. Haendel, M. A. Hegde, H. B. Himmelstein, D. S. Karis, K. Kunze, J. Lubiana, T. Matentzoglu, N. McMurry, J. Moxon, S. Mungall, C. J. Rutz, A. Unni, D. R. Willighagen, E. Winston, D. Gyori, B. M. 2022-07-10 doi:10.1101/2022.07.08.499378 Cold Spring Harbor Laboratory Press 2022-07-10 <![CDATA[ Phosphorylation and ubiquitination independent endocytosis of BRI1 ]]> https://biorxiv.org/content/10.1101/2022.07.11.499622v1?rss=1 Russinova, E. Alves Neubus Claus, L. Liu, D. Hohmann, U. Vukasinovic, N. Pleskot, R. Liu, J. Schiffner, A. Jaillais, Y. Wu, G. Wolf, S. Van Damme, D. Hothorn, M. 2022-07-14 doi:10.1101/2022.07.11.499622 Cold Spring Harbor Laboratory Press 2022-07-14 <![CDATA[ Teeth outside the mouth: the evolution and development of shark denticles ]]> https://biorxiv.org/content/10.1101/2022.07.13.499989v1?rss=1 Cooper, R. L. Nicklin, E. F. Rasch, L. J. Fraser, G. J. 2022-07-15 doi:10.1101/2022.07.13.499989 Cold Spring Harbor Laboratory Press 2022-07-15 <![CDATA[ Advected percolation in the actomyosin cortex drives amoeboid cell motility ]]> https://biorxiv.org/content/10.1101/2022.07.14.500109v1?rss=1 Garcia-Arcos, J. M. Ziegler, J. Grigolon, S. Reymond, L. Shajepal, G. Cattin, C. J. Lomakin, A. Mueller, D. J. Ruprecht, V. Wieser, S. Voituriez, R. Piel, M. 2022-07-14 doi:10.1101/2022.07.14.500109 Cold Spring Harbor Laboratory Press 2022-07-14 <![CDATA[ Genetic variation in correlated regulatory region of Immunity ]]> https://biorxiv.org/content/10.1101/2022.07.21.500922v1?rss=1 Avalos, D. Rey, G. Ribeiro, D. M. Ramisch, A. Dermitzakis, E. T. Delaneau, O. 2022-07-22 doi:10.1101/2022.07.21.500922 Cold Spring Harbor Laboratory Press 2022-07-22 <![CDATA[ Dynamic metabolome profiling uncovers potential TOR signaling genes ]]> https://biorxiv.org/content/10.1101/2022.07.25.500770v1?rss=1 Reichling, S. Doubleday, P. F. Germade, T. Bergmann, A. Loewith, R. Sauer, U. Holbrook-Smith, D. 2022-07-26 doi:10.1101/2022.07.25.500770 Cold Spring Harbor Laboratory Press 2022-07-26 <![CDATA[ Neural integration and segregation revealed by a joint time-vertex connectome spectral analysis ]]> https://biorxiv.org/content/10.1101/2022.07.26.501543v1?rss=1 Rue Queralt, J. Mancini, V. Rochas, V. Latreche, C. Uhlhaas, P. Michel, C. Plomp, G. Eliez, S. Hagmann, P. 2022-07-27 doi:10.1101/2022.07.26.501543 Cold Spring Harbor Laboratory Press 2022-07-27 <![CDATA[ Retromer oligomerization drives SNX-BAR coat assembly and membrane constriction ]]> https://biorxiv.org/content/10.1101/2022.07.27.501715v1?rss=1 Gopaldass, N. De Leo, M. G. G. Courtellement, T. Mercier, V. Bissig, C. Roux, A. Mayer, A. 2022-07-29 doi:10.1101/2022.07.27.501715 Cold Spring Harbor Laboratory Press 2022-07-29 <![CDATA[ An Sfi1-like centrin-interacting centriolar plaque protein affects nuclear microtubule homeostasis. ]]> https://biorxiv.org/content/10.1101/2022.07.28.501831v1?rss=1 Wenz, C. Simon, C. S. Romao, T. P. Stuermer, V. Machado, M. Klages, N. Klemmer, A. Voss, Y. Ganter, M. Brochet, M. Guizetti, J. 2022-07-29 doi:10.1101/2022.07.28.501831 Cold Spring Harbor Laboratory Press 2022-07-29 <![CDATA[ DLC3/Cv-c function in testis development in humans and Drosophila: implication for variants of sex development ]]> https://biorxiv.org/content/10.1101/2022.07.28.501838v1?rss=1 Sotillos, S. von der Decken, I. Domenech Mercade, I. Srinivasan, S. Vanni, S. Nef, S. Biason-Lauber, A. Rodriguez Gutierrez, D. C-G Hombria, J. 2022-08-01 doi:10.1101/2022.07.28.501838 Cold Spring Harbor Laboratory Press 2022-08-01 <![CDATA[ Spatio-temporal regulation of endocytic protein assembly by SH3 domains in yeast ]]> https://biorxiv.org/content/10.1101/2022.08.11.503583v1?rss=1 Hummel, D. R. Kaksonen, M. 2022-08-11 doi:10.1101/2022.08.11.503583 Cold Spring Harbor Laboratory Press 2022-08-11 <![CDATA[ EEG-based Motor Imagery Decoding via Graph Signal Processing on Smooth Learned Graphs ]]> https://biorxiv.org/content/10.1101/2022.08.13.503836v1?rss=1 Miri, M. Abootalebi, V. Saeedi-Sourck, H. Behjat, H. 2022-08-15 doi:10.1101/2022.08.13.503836 Cold Spring Harbor Laboratory Press 2022-08-15 <![CDATA[ Concurrent measures of impulsive action and choice are partially related and differentially modulated by dopamine D1- and D2-like receptors in a rat model of impulsivity ]]> https://biorxiv.org/content/10.1101/2022.08.16.504077v1?rss=1 Belles, L. Arrondeau, C. Uruena-Mendez, G. Ginovart, N. 2022-08-16 doi:10.1101/2022.08.16.504077 Cold Spring Harbor Laboratory Press 2022-08-16 <![CDATA[ Targeted protein degradation reveals BET bromodomains as the cellular target of Hedgehog Pathway Inhibitor-1 ]]> https://biorxiv.org/content/10.1101/2022.08.16.504103v1?rss=1 Bagka, M. Choi, H. Heritier, M. Scapozza, L. Wu, Y. Hoogendoorn, S. 2022-08-16 doi:10.1101/2022.08.16.504103 Cold Spring Harbor Laboratory Press 2022-08-16 <![CDATA[ Inventa: a computational tool to discover chemical novelty in natural extracts libraries ]]> https://biorxiv.org/content/10.1101/2022.08.25.505324v1?rss=1 Quiros-Guerrero, L. M. Nothias, L.-F. Gaudry, A. Marcourt, L. Allard, P.-M. Rutz, A. David, B. Ferreira, E. Wolfender, J.-L. 2022-08-26 doi:10.1101/2022.08.25.505324 Cold Spring Harbor Laboratory Press 2022-08-26 <![CDATA[ Not4-dependent targeting of MMF1 mRNA to mitochondria limits its expression via ribosome pausing, Egd1 ubiquitination, Caf130, No-Go-Decay and autophagy ]]> https://biorxiv.org/content/10.1101/2022.08.29.502450v1?rss=1 Chen, S. Allen, G. Panasenko, O. O. Collart, M. A. 2022-08-29 doi:10.1101/2022.08.29.502450 Cold Spring Harbor Laboratory Press 2022-08-29 <![CDATA[ Sequential And Directional Insulation By Conserved CTCF Sites Underlies The Hox Timer In Pseudo-Embryos ]]> https://biorxiv.org/content/10.1101/2022.08.29.505673v1?rss=1 Rekaik, H. Lopez-Delisle, L. Hintermann, A. Mascrez, B. Bochaton, C. Duboule, D. 2022-08-29 doi:10.1101/2022.08.29.505673 Cold Spring Harbor Laboratory Press 2022-08-29 <![CDATA[ Persistent virus-specific and clonally expanded antibody secreting cells respond to induced self antigen in the CNS ]]> https://biorxiv.org/content/10.1101/2022.08.29.505678v1?rss=1 Agrafiotis, A. Dizerens, R. Vincenti, I. Wagner, I. Kuhn, R. Shlesinger, D. Manero-Carranza, M. Cotet, T.-S. Hong, K.-L. Page, N. Fonta, N. Shammas, G. Mariotte, A. Piccinno, M. Kreutzfeldt, M. Gruntz, B. Ehling, R. Genovese, A. Pedrioli, A. Dounas, A. Franzenburg, S. Kavaka, V. Gerdes, L. A. Dornmair, K. Beltran, E. Oxenius, A. Reddy, S. T. Merkler, D. Yermanos, A. 2022-08-29 doi:10.1101/2022.08.29.505678 Cold Spring Harbor Laboratory Press 2022-08-29 <![CDATA[ Global Phylogeny of the Brassicaceae Provides Important Insights into Gene Discordance ]]> https://biorxiv.org/content/10.1101/2022.09.01.506188v1?rss=1 1,000 genes, almost all 349 genera and 53 tribes) and plastome (60 genes, 79% of the genera, all tribes) data. We found cytonuclear discordance between nuclear and plastome-derived phylogenies, which is likely a result of rampant hybridisation among closely and more distantly related species, and highlight rogue taxa. To evaluate the impact of this rampant hybridisation on the nuclear phylogeny reconstruction, we performed four different sampling routines that increasingly removed variable data and likely paralogs. Our resulting cleaned subset of 297 nuclear genes revealed high support for the tribes, while support for the main lineages remained relatively low. Calibration based on the 20 most clock-like nuclear genes suggests a late Eocene to late Oligocene icehouse origin of the family. Finally, we propose five new or re-established tribes, including the recognition of Arabidopsideae, a monotypic tribe to accommodate Arabidopsis. With a worldwide community of thousands of researchers working on this family, our new, densely sampled family phylogeny will be an indispensable tool to further highlight Brassicaceae as an excellent model family for studies on biodiversity and plant biology. ]]> Hendriks, K. P. Kiefer, C. Al-Shehbaz, I. A. Bailey, C. D. Hooft van Huysduynen, A. A. C. Nikolov, L. Nauheimer, L. Zuntini, A. R. German, D. A. Franzke, A. Koch, M. A. Lysak, M. A. Toro-Nunez, O. Ozudogru, B. Invernon, V. R. Walden, N. Maurin, O. Hay, N. Sushkov, P. Mandakova, T. Thulin, M. Windham, M. Resetnik, I. Spaniel, S. Ly, E. Pires, J. C. Harkess, A. Neuffer, B. Vogt, R. Braeuchler, C. Rainer, H. Janssens, S. Schmull, M. Forrest, A. Guggisberg, A. Zmarzty, S. Lepschi, B. Scarlett, N. Stauffer, F. W. Schonberger, I. Heenan, P. Baker, W. J. Fore 2022-09-01 doi:10.1101/2022.09.01.506188 Cold Spring Harbor Laboratory Press 2022-09-01 <![CDATA[ Scream's roughness confers a privileged access to the brain during sleep ]]> https://biorxiv.org/content/10.1101/2022.09.05.506631v1?rss=1 Legendre, G. Y. T. Moyne, M. Dominguez-Borras, J. Kumar, S. Sterpenich, V. Schwartz, S. Arnal, L. 2022-09-06 doi:10.1101/2022.09.05.506631 Cold Spring Harbor Laboratory Press 2022-09-06 <![CDATA[ A PI(3,5)P2 probe reveals PIKfyve is required for Rab7 acquisition and the delivery and fusion of early macropinosomes to phagosomes ]]> https://biorxiv.org/content/10.1101/2022.09.19.508510v1?rss=1 Buckley, C. M. Maib, H. Vines, J. H. Gueho, A. Soldati, T. Murray, D. H. King, J. S. 2022-09-19 doi:10.1101/2022.09.19.508510 Cold Spring Harbor Laboratory Press 2022-09-19 <![CDATA[ Tubulin engineering by semisynthesis reveals that polyglutamylation directs detyrosination ]]> https://biorxiv.org/content/10.1101/2022.09.20.508649v1?rss=1 Ebberink, E. Fernandes, S. Hatzopoulos, G. Agashe, N. Guidotti, N. Reichart, T. M. Reymond, L. Velluz, M. C. Pourroy, C. Janke, C. Gonczy, P. Fierz, B. Aumeier, C. 2022-09-20 doi:10.1101/2022.09.20.508649 Cold Spring Harbor Laboratory Press 2022-09-20 <![CDATA[ Quantitative proteomic analysis of skeletal muscles from wild type and transgenic mice carrying recessive Ryr1 mutations linked to congenital myopathies ]]> https://biorxiv.org/content/10.1101/2022.09.26.509474v1?rss=1 Eckhardt, J. Ruiz, A. Koenig, S. Frieden, M. Schmidt, A. Treves, S. Zorzato, F. 2022-09-27 doi:10.1101/2022.09.26.509474 Cold Spring Harbor Laboratory Press 2022-09-27 <![CDATA[ Technical insights into fluorescence lifetime microscopy of mechanosensitive Flipper probes ]]> https://biorxiv.org/content/10.1101/2022.09.28.509885v1?rss=1 Roffay, C. Garcia Arcos, J. M. Chapuis, P. Lopez-Andarias, J. Colom, A. Tomba, C. Di Meglio, I. Matile, S. Roux, A. Mercier, V. 2022-09-30 doi:10.1101/2022.09.28.509885 Cold Spring Harbor Laboratory Press 2022-09-30 <![CDATA[ Mild replication stress causes premature centriole disengagement via a sub-critical Plk1 activity under the control of ATR-Chk1 ]]> https://biorxiv.org/content/10.1101/2022.09.29.510042v1?rss=1 Dwivedi, D. Harry, D. Meraldi, P. 2022-09-30 doi:10.1101/2022.09.29.510042 Cold Spring Harbor Laboratory Press 2022-09-30 <![CDATA[ Chromatin regulators in the TBX1 network confer risk for conotruncal heart defects in 22q11.2DS and sporadic congenital heart disease ]]> https://biorxiv.org/content/10.1101/2022.09.30.507111v1?rss=1 Zhao, Y. Wang, Y. Shi, L. McDonald-McGinn, D. M. Crowley, T. B. McGinn, D. E. Tran, O. T. Miller, D. Zackai, E. Johnston, H. R. Chow, E. Vorstman, J. A. S. Vingerhoets, C. van Amelsvoort, T. Gothelf, D. Swillen, A. Breckpot, J. Vermeesch, J. R. Eliez, S. Schneider, M. van den Bree, M. B. Owen, M. J. Kates, W. Repetto, G. M. Shashi, V. Schoch, K. Bearden, C. E. Digilio, M. C. E. Unolt, M. Putotto, C. Marino, B. Pontillo, M. Armando, M. Vicari, S. Angkustsiri, K. Campbell, L. Busa, T. Heine-Suner, D. Murphy, K. C. Murphy, D. Garcia-Minaur, S. Fernandez, L 2022-10-03 doi:10.1101/2022.09.30.507111 Cold Spring Harbor Laboratory Press 2022-10-03 <![CDATA[ S100A4 plays a role in mouse arterial smooth muscle cell motility. Implication for intimal thickening formation. ]]> https://biorxiv.org/content/10.1101/2022.09.30.510253v1?rss=1 Cardoso dos Santos, L. M. Klingelhofer, J. Bochaton-Piallat, M.-L. 2022-10-03 doi:10.1101/2022.09.30.510253 Cold Spring Harbor Laboratory Press 2022-10-03 <![CDATA[ A Zur-mediated transcriptional regulation of the zinc export system ]]> https://biorxiv.org/content/10.1101/2022.09.30.510347v1?rss=1 Ducret, V. Gonzalez, D. Leoni, S. Valentini, M. Perron, K. 2022-10-01 doi:10.1101/2022.09.30.510347 Cold Spring Harbor Laboratory Press 2022-10-01 <![CDATA[ Modelling Membrane Reshaping by Staged Polymerization of ESCRT-III Filaments ]]> https://biorxiv.org/content/10.1101/2022.10.03.508498v1?rss=1 Jiang, X. Harker-Kirschneck, L. Vanhille Campos, C. Pfitzner, A.-K. Lominadze, E. Roux, A. Baum, B. Saric, A. 2022-10-04 doi:10.1101/2022.10.03.508498 Cold Spring Harbor Laboratory Press 2022-10-04 <![CDATA[ Distinct phenotype of SARS-CoV-2 Omicron BA.1 in human primary cells but no increased host range in cell lines of putative mammalian reservoir species ]]> https://biorxiv.org/content/10.1101/2022.10.04.510352v1?rss=1 Essaidi-Laziosi, M. Perez Rodriguez, F. J. Alvarez, C. Sattonnet-Roche, P. Torriani, G. Bekliz, M. Adea, K. Lenk, M. Preiser, W. Suliman, T. Muller, M. A. Drosten, C. Kaiser, L. Eckerle, I. 2022-10-04 doi:10.1101/2022.10.04.510352 Cold Spring Harbor Laboratory Press 2022-10-04 <![CDATA[ SARS-CoV-2 infection alkalinizes the ERGIC and lysosomes through the viroporin activity of the viral envelope protein ]]> https://biorxiv.org/content/10.1101/2022.10.04.510830v1?rss=1 Want, W.-A. Carreras Sureda, A. Demaurex, N. 2022-10-06 doi:10.1101/2022.10.04.510830 Cold Spring Harbor Laboratory Press 2022-10-06 <![CDATA[ Apical-to-basal graded ROS metabolism in intact Hydra leads to distinct levels of injury-induced ROS signaling in apical and basal regenerating tips ]]> https://biorxiv.org/content/10.1101/2022.10.04.510867v1?rss=1 Suknovic, N. S. Reiter-Karam, S. Chara, O. Buzgariu, W. Martinvalet, D. Galliot, B. 2022-10-05 doi:10.1101/2022.10.04.510867 Cold Spring Harbor Laboratory Press 2022-10-05 <![CDATA[ An RNA modification enzyme directly senses reactive oxygen species for translational regulation in Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2022.10.12.511899v1?rss=1 Lee, W. L. Sinha, A. Lam, L. N. Loo, H. L. Liang, J. Ho, P. Liang, C. Chan, C. Begley, T. Kline, K. A. Dedon, P. 2022-10-13 doi:10.1101/2022.10.12.511899 Cold Spring Harbor Laboratory Press 2022-10-13 <![CDATA[ Circadian clock disruption promotes the degeneration of dopaminergic neurons ]]> https://biorxiv.org/content/10.1101/2022.10.15.512376v1?rss=1 Majcin Dorcikova, M. Duret, L. C. Pottie, E. Nagoshi, E. 2022-10-17 doi:10.1101/2022.10.15.512376 Cold Spring Harbor Laboratory Press 2022-10-17 <![CDATA[ Purine and carbohydrate availability drive Enterococcus faecalis fitness during wound infection ]]> https://biorxiv.org/content/10.1101/2022.10.17.512645v1?rss=1 Tan, C. A. Z. Chong, K. K. L. Yeong, D. Y. X. Ng, C. H. M. Ismail, M. H. Tay, V. S. Y. Ali, Y. Kline, K. A. 2022-10-18 doi:10.1101/2022.10.17.512645 Cold Spring Harbor Laboratory Press 2022-10-18 <![CDATA[ Mitoxantrone Targets Both Host and Bacteria to Overcome Vancomycin Resistance in Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2022.10.24.513631v1?rss=1 da Silva, R. A. G. Wong, J. J. Antypas, H. Choo, P. Y. Goh, K. Jolly, S. Liang, C. Sing, L. T. K. Veleba, M. Hu, G. Chen, J. Kline, K. A. 2022-10-25 doi:10.1101/2022.10.24.513631 Cold Spring Harbor Laboratory Press 2022-10-25 <![CDATA[ Co-option of the transcription factor SALL1 in mole ovotestis formation ]]> https://biorxiv.org/content/10.1101/2022.10.28.514220v1?rss=1 Schindler, M. Osterwalder, M. Harabula, I. Wittler, L. Tzika, A. C. Dechmann, D. Vingron, M. Visel, A. Haas, S. Real, F. M. 2022-10-28 doi:10.1101/2022.10.28.514220 Cold Spring Harbor Laboratory Press 2022-10-28 <![CDATA[ Increased neuron density in the midbrain of foveate birds results from profound change in tissue morphogenesis ]]> https://biorxiv.org/content/10.1101/2022.10.29.514341v1?rss=1 View larger version (32K): org.highwire.dtl.DTLVardef@1861345org.highwire.dtl.DTLVardef@15b5557org.highwire.dtl.DTLVardef@13fec7borg.highwire.dtl.DTLVardef@1bea1bb_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIThe presence of a fovea is associated with increased neuron density in the optic tectum C_LIO_LIFovea number and deepness influence neuron density in the optic tectum C_LIO_LIIncreased neuron density in the upper layers of the optic tectum requires major developmental changes C_LIO_LIPostponed cell migration, prolonged cell proliferation, hindered tissue growth are necessary settings for achieving high neuron density C_LI ]]> Rodrigues, T. Dib, L. Brethaut, E. Matter, M. M. Matter-Sadzinski, L. Matter, J.-M. 2022-10-30 doi:10.1101/2022.10.29.514341 Cold Spring Harbor Laboratory Press 2022-10-30 <![CDATA[ Inactivation of Influenza A virus by pH conditions encountered in expiratory aerosol particles results from localized conformational changes within Haemagglutinin and Matrix 1 proteins. ]]> https://biorxiv.org/content/10.1101/2022.11.01.514690v1?rss=1 David, S. C. Vadas, O. Glas, I. Schaub, A. Luo, B. D'Angelo, G. C. Paz Montoya, J. Bluvshtein, N. Hugentobler, W. Klein, L. Motos, G. Pohl, M. Violaki, K. Nenes, A. Krieger, U. Stertz, S. Peter, T. Kohn, T. 2022-11-01 doi:10.1101/2022.11.01.514690 Cold Spring Harbor Laboratory Press 2022-11-01 <![CDATA[ Organelle-specific photoactivation and dual-isotope labeling strategy reveals phosphatidylethanolamine metabolic flux ]]> https://biorxiv.org/content/10.1101/2022.11.03.514994v1?rss=1 Simon, C. Asaro, A. Feng, S. Riezman, H. 2022-11-04 doi:10.1101/2022.11.03.514994 Cold Spring Harbor Laboratory Press 2022-11-04 <![CDATA[ Depleting cationic lipids involved in antimicrobial resistance drives adaptive lipid remodeling in Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2022.11.04.515160v1?rss=1 Rashid, R. Nair, Z. J. Chia, D. M. H. Chong, K. K. L. Cazenave-Gassiot, A. Morley, S. A. Allen, D. K. Chen, S. L. Chng, S.-S. Wenk, M. R. Kline, K. A. 2022-11-04 doi:10.1101/2022.11.04.515160 Cold Spring Harbor Laboratory Press 2022-11-04 <![CDATA[ Insular cortex to ventral striatum synapses encode valence of social interaction ]]> https://biorxiv.org/content/10.1101/2022.11.08.515650v1?rss=1 Espinosa, P. Girard, B. Lucchini, M. Campanelli, F. Tiriticco, V. Bellone, C. 2022-11-09 doi:10.1101/2022.11.08.515650 Cold Spring Harbor Laboratory Press 2022-11-09 <![CDATA[ Nanoscopy of organelles and tissues with iterative ultrastructure expansion microscopy (iU-ExM) ]]> https://biorxiv.org/content/10.1101/2022.11.14.516383v1?rss=1 Louvel, V. Haase, R. Mercey, O. Laporte, M. H. Soldati-Favre, D. Hamel, V. Guichard, P. 2022-11-15 doi:10.1101/2022.11.14.516383 Cold Spring Harbor Laboratory Press 2022-11-15 <![CDATA[ Cell type-specific assessment of cholesterol distribution in models of neurodevelopmental disorders ]]> https://biorxiv.org/content/10.1101/2022.11.16.516849v1?rss=1 Czernecki, C. Dixit, S. Riezman, I. Innocenti, S. Pfrieger, F. Riezman, H. Scheiffele, P. 2022-11-17 doi:10.1101/2022.11.16.516849 Cold Spring Harbor Laboratory Press 2022-11-17 <![CDATA[ Architecture of chloroplast TOC-TIC translocon supercomplex ]]> https://biorxiv.org/content/10.1101/2022.11.20.517165v1?rss=1 Liu, H. Li, A. Rochaix, J.-D. Liu, Z. 2022-11-20 doi:10.1101/2022.11.20.517165 Cold Spring Harbor Laboratory Press 2022-11-20 <![CDATA[ Running Kinesin-1 shapes the microtubule acetylation gradient ]]> https://biorxiv.org/content/10.1101/2022.12.01.518806v1?rss=1 Andreu-Carbo, M. Egoldt, C. Velluz, M.-C. Aumeier, C. 2022-12-02 doi:10.1101/2022.12.01.518806 Cold Spring Harbor Laboratory Press 2022-12-02 <![CDATA[ PDX3 is important for carbon/nitrogen balance in Arabidopsis associated with distinct environmental conditions ]]> https://biorxiv.org/content/10.1101/2022.12.06.519276v1?rss=1 Steensma, P. Eisenhut, M. Colinas, M. Rosado-Souza, L. Fernie, A. R. Weber, A. P. M. Fitzpatrick, T. B. 2022-12-08 doi:10.1101/2022.12.06.519276 Cold Spring Harbor Laboratory Press 2022-12-08 <![CDATA[ The utility and caveat of split-GAL4s in the study of neurodegeneration ]]> https://biorxiv.org/content/10.1101/2022.12.06.519338v1?rss=1 Stickley, L. Nagoshi, E. 2022-12-06 doi:10.1101/2022.12.06.519338 Cold Spring Harbor Laboratory Press 2022-12-06 <![CDATA[ Proximity labelling allows to study novel factors in chloroplast development ]]> https://biorxiv.org/content/10.1101/2022.12.08.519630v1?rss=1 Wurzinger, B. Stael, S. Leonardelli, M. Perolo, C. Melzer, M. Chaturvedi, P. Afjehi-Sadat, L. Weckwerth, W. Teige, M. 2022-12-10 doi:10.1101/2022.12.08.519630 Cold Spring Harbor Laboratory Press 2022-12-10 <![CDATA[ Subcellular location defines GPCR signal transduction ]]> https://biorxiv.org/content/10.1101/2022.12.12.520050v1?rss=1 Radoux-Mergault, A. Oberhauser, L. Aureli, S. Gervasio, F. L. Stoeber, M. 2022-12-12 doi:10.1101/2022.12.12.520050 Cold Spring Harbor Laboratory Press 2022-12-12 <![CDATA[ Habitual ground nesting in the Bugoma Forest chimpanzees (Pan troglodytes schweinfurthii), Uganda. ]]> https://biorxiv.org/content/10.1101/2022.12.14.520400v1?rss=1 Hobaiter, C. Klein, H. Gruber, T. 2022-12-16 doi:10.1101/2022.12.14.520400 Cold Spring Harbor Laboratory Press 2022-12-16 <![CDATA[ Polarity-driven three-dimensional spontaneous rotation of a cell doublet ]]> https://biorxiv.org/content/10.1101/2022.12.21.521355v1?rss=1 Lu, L. Guyomar, T. Vagne, Q. Berthoz, R. Torres-Sanchez, A. Lieb, M. Martin-Lemaitre, C. van Unen, J. Honigmann, A. Pertz, O. Salbreux, G. Riveline, D. 2022-12-22 doi:10.1101/2022.12.21.521355 Cold Spring Harbor Laboratory Press 2022-12-22 <![CDATA[ Friction patterns guide actin network contraction ]]> https://biorxiv.org/content/10.1101/2022.12.21.521384v1?rss=1 Colin, A. Orhant-Prioux, M. Guerin, C. Savinov, M. Scarfone, I. Roux, A. De La Cruz, E. M. Mogilner, A. Thery, M. Blanchoin, L. 2022-12-22 doi:10.1101/2022.12.21.521384 Cold Spring Harbor Laboratory Press 2022-12-22 <![CDATA[ The lipid transfer proteins Nir2 and Nir3 sustain phosphoinositide signaling and actin dynamics during phagocytosis ]]> https://biorxiv.org/content/10.1101/2022.12.21.521447v1?rss=1 Kaba, M. Carreras-Sureda, A. Nunes-Hasler, P. Demaurex, N. 2022-12-23 doi:10.1101/2022.12.21.521447 Cold Spring Harbor Laboratory Press 2022-12-23 <![CDATA[ Past human expansions shaped the spatial pattern of Neanderthal ancestry ]]> https://biorxiv.org/content/10.1101/2022.12.22.521596v1?rss=1 Quilodran, C. S. Rio, J. Tsoupas, A. Currat, M. 2022-12-22 doi:10.1101/2022.12.22.521596 Cold Spring Harbor Laboratory Press 2022-12-22 <![CDATA[ Is short sleep bad for the brain? Brain structure and cognitive function in short sleepers ]]> https://biorxiv.org/content/10.1101/2022.12.22.521614v1?rss=1 Fjell, A. Sorensen, O. Amlien, I. K. Barre, W. Bartres-Faz, D. Boraxbekk, C.-J. Brandmaier, A. Demuth, I. Drevon, C. A. Ebmeier, K. Ghisletta, P. Kievit, R. A. Kuhn, S. A. Nyberg, L. Madsen, K. S. Sole-Padulles, C. Vidal-Pineiro, D. Wagner, G. Wang, Y. Watne, L. O. Walhovd, K. B. 2022-12-22 doi:10.1101/2022.12.22.521614 Cold Spring Harbor Laboratory Press 2022-12-22 <![CDATA[ Loss of NR5A1 in Sertoli cells after sex determination changes their cellular identity and induces their death by anoikis ]]> https://biorxiv.org/content/10.1101/2023.01.04.522755v1?rss=1 SOUALI-CRESPO, S. CONDREA, D. VERNET, N. FERET, B. KLOPFENSTEIN, M. GRANDGIRARD, E. ALUNNI, V. CERCIAT, M. JUNG, M. MAYERE, C. NEF, S. MARK, M. CHALMEL, F. GHYSELINCK, N. B. 2023-01-04 doi:10.1101/2023.01.04.522755 Cold Spring Harbor Laboratory Press 2023-01-04 <![CDATA[ Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors ]]> https://biorxiv.org/content/10.1101/2023.01.09.523195v1?rss=1 Neirijnck, Y. Sararols, P. Kuhne, F. Mayere, C. Nef, S. Schedl, A. 2023-01-09 doi:10.1101/2023.01.09.523195 Cold Spring Harbor Laboratory Press 2023-01-09 <![CDATA[ Mechanism of ribosome-associated mRNA degradation during tubulin autoregulation ]]> https://biorxiv.org/content/10.1101/2023.01.12.523749v1?rss=1 Höpfler, M. Absmeier, E. Peak-Chew, S.-Y. Vartholomaiou, E. Passmore, L. A. Gasic, I. Hegde, R. S. 2023-01-12 doi:10.1101/2023.01.12.523749 Cold Spring Harbor Laboratory Press 2023-01-12 <![CDATA[ Probing the sub-cellular mechanisms of LCA5-Leber Congenital Amaurosis and associated gene therapy with expansion microscopy ]]> https://biorxiv.org/content/10.1101/2023.01.17.524360v1?rss=1 Faber, S. Mercey, O. Junger, K. Garanto, A. Ueffing, M. Collin, R. W. J. Boldt, K. Guichard, P. Hamel, V. Roepman, R. 2023-01-18 doi:10.1101/2023.01.17.524360 Cold Spring Harbor Laboratory Press 2023-01-18 <![CDATA[ Ensemble of deep learning language models to support the creation of living systematic reviews for the COVID-19 literature: a retrospective study ]]> https://biorxiv.org/content/10.1101/2023.01.18.524571v1?rss=1 Knafou, J. Haas, Q. Borissov, N. Counotte, M. J. Low, N. Imeri, H. Ipekci, A. M. Buitrago-Garcia, D. Heron, L. Amini, P. Teodoro, D. 2023-01-19 doi:10.1101/2023.01.18.524571 Cold Spring Harbor Laboratory Press 2023-01-19 <![CDATA[ Structural and regulatory insights into the glideosome-associated connector from Toxoplasma gondii ]]> https://biorxiv.org/content/10.1101/2023.01.23.525158v1?rss=1 Kumar, A. Vadas, O. Dos Santos Pacheco, N. Zhang, X. Chao, K. Darvill, N. Rasmussen, H. Xu, Y. Lin, G. Stylianou, F. Pedersen, J. S. Rouse, S. Morgan, M. Soldati-Favre, D. Matthews, S. 2023-01-23 doi:10.1101/2023.01.23.525158 Cold Spring Harbor Laboratory Press 2023-01-23 <![CDATA[ Hsf1 and the molecular chaperone Hsp90 support a "rewiring stress response" leading to an adaptive cell size increase in chronic stress ]]> https://biorxiv.org/content/10.1101/2023.01.25.525547v1?rss=1 Maiti, S. Bhattacharya, K. Wider, D. Hany, D. Panasenko, O. Bernasconi, L. Hulo, N. Picard, D. 2023-01-25 doi:10.1101/2023.01.25.525547 Cold Spring Harbor Laboratory Press 2023-01-25 <![CDATA[ Neural substrates of parallel devaluation-sensitive and devaluation-insensitive Pavlovian learning in humans ]]> https://biorxiv.org/content/10.1101/2023.01.26.525637v1?rss=1 Pool, E. R. Pauli, W. M. Cross, L. O'Doherty, J. P. 2023-01-27 doi:10.1101/2023.01.26.525637 Cold Spring Harbor Laboratory Press 2023-01-27 <![CDATA[ New tools to study the interaction between integrins and latent TGFbeta1 ]]> https://biorxiv.org/content/10.1101/2023.01.26.525682v1?rss=1 Bachmann, M. Kessler, J. Burri, E. Wehrle-Haller, B. 2023-01-26 doi:10.1101/2023.01.26.525682 Cold Spring Harbor Laboratory Press 2023-01-26 <![CDATA[ Efficient image analysis for large-scale next generation histopathology using pAPRica ]]> https://biorxiv.org/content/10.1101/2023.01.27.525687v1?rss=1 Scholler, J. Jonsson, J. Jorda-Siquier, T. Gantar, I. Batti, L. Cheeseman, B. Pages, S. Sbalzarini, I. F. Lamy, C. M. 2023-01-28 doi:10.1101/2023.01.27.525687 Cold Spring Harbor Laboratory Press 2023-01-28 <![CDATA[ Plasmodium ARK2-EB1 axis drives the unconventional spindle dynamics, scaffold formation, and chromosome segregation of sexual transmission stages ]]> https://biorxiv.org/content/10.1101/2023.01.29.526106v1?rss=1 Zeeshan, M. Rea, E. Abel, S. Vukusic, K. Markus, R. Brady, D. Eze, A. A. Rashpa, R. Balestra, A. Bottrill, A. Brochet, M. Guttery, D. Tolic, I. M. Holder, A. A. Le Roch, K. G. Tromer, E. Tewari, R. 2023-01-31 doi:10.1101/2023.01.29.526106 Cold Spring Harbor Laboratory Press 2023-01-31 <![CDATA[ The ecdysone receptor promotes or suppresses proliferation according toligand level ]]> https://biorxiv.org/content/10.1101/2023.02.10.527985v1?rss=1 Perez-Mockus, G. Cocconi, L. Alexandre, C. Aerne, B. L. Salbreux, G. Vincent, J.-P. 2023-02-11 doi:10.1101/2023.02.10.527985 Cold Spring Harbor Laboratory Press 2023-02-11 <![CDATA[ Decoding the content of working memory in school-aged children ]]> https://biorxiv.org/content/10.1101/2023.02.10.527990v1?rss=1 Turoman, N. Fiave, P. A. Zahnd, C. deBettencourt, M. T. Vergauwe, E. 2023-02-12 doi:10.1101/2023.02.10.527990 Cold Spring Harbor Laboratory Press 2023-02-12 <![CDATA[ Model-based frontal cortex analysis reveals origins of human non-verbal communication ]]> https://biorxiv.org/content/10.1101/2023.02.13.528425v1?rss=1 Ceravolo, L. Debracque, C. Pool, E. Gruber, T. Grandjean, D. 2023-02-14 doi:10.1101/2023.02.13.528425 Cold Spring Harbor Laboratory Press 2023-02-14 <![CDATA[ CCDC15 localizes to the centriole inner scaffold and regulates centriole integrity and ciliogenesis ]]> https://biorxiv.org/content/10.1101/2023.02.16.528810v1?rss=1 Arslanhan, M. D. Steib, E. Hamel, V. Guichard, P. Firat-Karalar, E. N. 2023-02-18 doi:10.1101/2023.02.16.528810 Cold Spring Harbor Laboratory Press 2023-02-18 <![CDATA[ Active mesh and neural network pipeline for cell aggregate segmentation ]]> https://biorxiv.org/content/10.1101/2023.02.17.528925v1?rss=1 Smith, M. B. Salbreux, G. Dunsby, C. Sparks, H. Almagro, J. Behrens, A. Chaigne, A. 2023-02-21 doi:10.1101/2023.02.17.528925 Cold Spring Harbor Laboratory Press 2023-02-21 <![CDATA[ Truly dorsal: nonlinear integration of motion signals is required to account for the responses of pattern cells in rat visual cortex ]]> https://biorxiv.org/content/10.1101/2023.02.17.528967v1?rss=1 Matteucci, G. Marotti, R. B. Zattera, B. Zoccolan, D. 2023-02-18 doi:10.1101/2023.02.17.528967 Cold Spring Harbor Laboratory Press 2023-02-18 <![CDATA[ Co-chaperone-mediated post-translational control of efflux pump induction underlies adaptive β-lactam resistance in Caulobacter crescentus. ]]> https://biorxiv.org/content/10.1101/2023.02.20.529182v1?rss=1 Costafrolaz, J. Panis, G. Casu, B. Ardissone, S. Degeorges, L. Pilhofer, M. Viollier, P. H. 2023-02-20 doi:10.1101/2023.02.20.529182 Cold Spring Harbor Laboratory Press 2023-02-20 <![CDATA[ Signalling-dependent refinement of cell fate choice during tissue remodelling ]]> https://biorxiv.org/content/10.1101/2023.02.21.529250v1?rss=1 Herszterg, S. de Gennes, M. Cicolini, S. Huang, A. Alexandre, C. Smith, M. B. Araujo, H. Vincent, J.-P. Salbreux, G. 2023-02-22 doi:10.1101/2023.02.21.529250 Cold Spring Harbor Laboratory Press 2023-02-22 <![CDATA[ Specific subcellular localization drives the different functions of CDC42 isoforms during migration ]]> https://biorxiv.org/content/10.1101/2023.02.27.528078v1?rss=1 Ravichandran, Y. Hanisch, J. Murray, K. Roca, V. Dingli, F. Loew, D. Sabatet, V. Boeda, B. Etienne-Manneville, S. 2023-02-27 doi:10.1101/2023.02.27.528078 Cold Spring Harbor Laboratory Press 2023-02-27 <![CDATA[ Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse ]]> https://biorxiv.org/content/10.1101/2023.02.27.530236v1?rss=1 Muronova, J. Kherraf, Z. E. Giordani, E. Eckert, S. Cazin, C. Amiri-Yekta, A. Lambert, E. Chevalier, G. Martinez, G. Neirijnck, Y. Kühne, F. Wehrli, L. Klena, N. Hamel, V. Escoffier, J. Guichard, P. Coutton, C. Mustapha, S. F. B. Kharouf, M. Zouari, R. Thierry-Mieg, N. Nef, S. Geimer, S. Loeuillet, C. Ray, P. F. Arnoult, C. 2023-03-01 doi:10.1101/2023.02.27.530236 Cold Spring Harbor Laboratory Press 2023-03-01 <![CDATA[ Microbial community-scale metabolic modeling predicts personalized short-chain-fatty-acid production profiles in the human gut. ]]> https://biorxiv.org/content/10.1101/2023.02.28.530516v1?rss=1 Bohmann, N. Wilmanski, T. Levy, L. Lampe, J. Gurry, T. Rappaport, N. Diener, C. Gibbons, S. M. 2023-03-01 doi:10.1101/2023.02.28.530516 Cold Spring Harbor Laboratory Press 2023-03-01 <![CDATA[ The claustrum drives large-scale interactions of cortical circuits relevant to long-term memory ]]> https://biorxiv.org/content/10.1101/2023.03.02.530783v1?rss=1 Mutel, S. Renfer, J.-R. Rodriguez, I. Carleton, A. Salazar, R. F. 2023-03-02 doi:10.1101/2023.03.02.530783 Cold Spring Harbor Laboratory Press 2023-03-02 <![CDATA[ Multimodal neural correlates of childhood psychopathology ]]> https://biorxiv.org/content/10.1101/2023.03.02.530821v1?rss=1 Kebets, V. Piguet, C. Chen, J. Ooi, L. Q. R. Kirschner, M. Siffredi, V. Misic, B. Yeo, B. T. T. Bernhardt, B. 2023-03-03 doi:10.1101/2023.03.02.530821 Cold Spring Harbor Laboratory Press 2023-03-03 <![CDATA[ OneOPES, a combined enhanced sampling method to rule them all ]]> https://biorxiv.org/content/10.1101/2023.03.06.531337v1?rss=1 View larger version (24K): org.highwire.dtl.DTLVardef@88b5ceorg.highwire.dtl.DTLVardef@15817deorg.highwire.dtl.DTLVardef@8721bforg.highwire.dtl.DTLVardef@1b8b314_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Rizzi, V. Aureli, S. Ansari, N. Gervasio, F. L. 2023-03-07 doi:10.1101/2023.03.06.531337 Cold Spring Harbor Laboratory Press 2023-03-07 <![CDATA[ Destabilization of neuromuscular junctions and deregulation of activity-dependent signalling pathways in Myotonic Dystrophy type I ]]> https://biorxiv.org/content/10.1101/2023.03.08.531688v1?rss=1 Falcetta, D. Quirim, S. Cocchiararo, I. Cornut, M. Theodore, M. Stiefvater, A. Lin, S. Tintignac, L. Ivanek, R. Kinter, J. Ruegg, M. A. Sinnreich, M. Castets, P. 2023-03-10 doi:10.1101/2023.03.08.531688 Cold Spring Harbor Laboratory Press 2023-03-10 <![CDATA[ Leaf metabolic traits reveal hidden dimensions of plant form and function ]]> https://biorxiv.org/content/10.1101/2023.03.08.531692v1?rss=1 Walker, T. W. N. Schrodt, F. Allard, P.-M. Defossez, E. Jassey, V. E. Schuman, M. C. Alexander, J. M. Baines, O. Baldy, V. Bardgett, R. D. Capdevila, P. Coley, P. D. van Dam, N. M. David, B. Descombes, P. Endara, M.-J. Fernandez, C. Forrister, D. Gargallo-Garriga, A. Glauser, G. Marr, S. Neumann, S. Pellissier, L. Peters, K. Rasmann, S. Roessner, U. Salguero-Gomez, R. Sardans, J. Weckwerth, W. Wolfender, J.-L. Penuelas, J. 2023-03-10 doi:10.1101/2023.03.08.531692 Cold Spring Harbor Laboratory Press 2023-03-10 <![CDATA[ Finite Sample Adjustments for Average Equivalence Testing ]]> https://biorxiv.org/content/10.1101/2023.03.11.532179v1?rss=1 Boulaguiem, Y. Quartier, J. Lapteva, M. Kalia, Y. N. Victoria-Feser, M.-P. Guerrier, S. Couturier, D.-L. 2023-03-12 doi:10.1101/2023.03.11.532179 Cold Spring Harbor Laboratory Press 2023-03-12 <![CDATA[ Methods for addressing the protein-protein interaction between histone deacetylase 6 and ubiquitin ]]> https://biorxiv.org/content/10.1101/203372v1?rss=1 dos Santos Passos, C. Deschamps, N. Choi, Y. Cohen, R. E. Perozzo, R. Nurisso, A. Simoes-Pires, C. 2017-10-15 doi:10.1101/203372 Cold Spring Harbor Laboratory Press 2017-10-15 <![CDATA[ Germline determinants of the somatic mutation landscape in 2,642 cancer genomes ]]> https://biorxiv.org/content/10.1101/208330v1?rss=1 T mutagenesis at CpG dinucleotides, a ubiquitous mutational process acting across tissues. Analysis of somatic structural variation exposed complex rearrangement patterns, involving cycles of templated insertions and tandem duplications, in BRCA1-deficient tumours. Genome-wide association analysis implicated common genetic variation at the APOBEC3 gene cluster with reduced basal levels of somatic mutagenesis attributable to APOBEC cytidine deaminases across cancer types. We further inferred over a hundred polymorphic L1/LINE elements with somatic retrotransposition activity in cancer. Our study highlights the major impact of rare and common germline variants on mutational landscapes in cancer. ]]> Waszak, S. M. Tiao, G. Zhu, B. Rausch, T. Muyas, F. Rodriguez-Martin, B. Rabionet, R. Yakneen, S. Escaramis, G. Li, Y. Saini, N. Roberts, S. A. Demidov, G. M. Pitkanen, E. Delaneau, O. Heredia-Genestar, J. M. Weischenfeldt, J. Shringarpure, S. S. Chen, J. Nakagawa, H. Alexandrov, L. B. Drechsel, O. Dursi, L. J. Segre, A. V. Garrison, E. Erkek, S. Habermann, N. Urban, L. Khurana, E. Cafferkey, A. Hayashi, S. Imoto, S. Aaltonen, L. A. Alvarez, E. G. Baez-Ortega, A. Bailey, M. Bosio, M. Bruzos, A. L. Buchhalter, I. Bustamante, C. D. Calabrese, C. DiBiase, 2017-11-01 doi:10.1101/208330 Cold Spring Harbor Laboratory Press 2017-11-01 <![CDATA[ Beyond Bilingualism: multilingual experience correlates with caudate volume ]]> https://biorxiv.org/content/10.1101/209619v1?rss=1 Hervais-Adelman, A. Egorova, N. Golestani, N. 2017-10-27 doi:10.1101/209619 Cold Spring Harbor Laboratory Press 2017-10-27 <![CDATA[ Knowledge of the Neighborhood of the Reactive Site up to Three Atoms Can Predict Biochemistry and Protein Sequences ]]> https://biorxiv.org/content/10.1101/210039v1?rss=1 Hadadi, N. MohamadiPeyhani, H. Miskovic, L. Seijo, M. Hatzimanikatis, V. 2017-10-27 doi:10.1101/210039 Cold Spring Harbor Laboratory Press 2017-10-27 <![CDATA[ Acute physical exercise improves memory consolidation in humans via BDNF and endocannabinoid signaling ]]> https://biorxiv.org/content/10.1101/211227v1?rss=1 Marin Bosch, B. Bringard, A. Logrieco, M. G. Imobersteg, N. M. Ferretti, G. Thomas, A. Schwartz, S. Igloi, K. 2017-10-31 doi:10.1101/211227 Cold Spring Harbor Laboratory Press 2017-10-31 <![CDATA[ Reward and automatic processes in exercise behavior: A new approach and a systematic review ]]> https://biorxiv.org/content/10.1101/211425v1?rss=1 Cheval, B. Radel, R. Neva, J. L. Boyd, L. A. Swinnen, S. P. Sander, D. Boisgontier, M. 2017-10-30 doi:10.1101/211425 Cold Spring Harbor Laboratory Press 2017-10-30 <![CDATA[ Systematic analysis of the molecular architecture of endocytosis reveals a nanoscale actin nucleation template that drives efficient vesicle formation ]]> https://biorxiv.org/content/10.1101/217836v1?rss=1 Mund, M. van der Beek, J. A. Deschamps, J. Dmitrieff, S. Monster, J. L. Picco, A. Nedelec, F. Kaksonen, M. Ries, J. 2017-11-15 doi:10.1101/217836 Cold Spring Harbor Laboratory Press 2017-11-15 <![CDATA[ LSX: Automated reduction of gene-specific lineage evolutionary rate heterogeneity for multi-gene phylogeny inference ]]> https://biorxiv.org/content/10.1101/220053v1?rss=1 Rivera-Rivera, C. J. Montoya-Burgos, J. I. 2017-11-16 doi:10.1101/220053 Cold Spring Harbor Laboratory Press 2017-11-16 <![CDATA[ RESCUE OF AN AGGRESSIVE FEMALE SEXUAL COURTSHIP IN MICE BY CRISPR/Cas9 SECONDARY MUTATION IN VIVO. ]]> https://biorxiv.org/content/10.1101/226639v1?rss=1 Zakany, J. Duboule, D. 2017-11-29 doi:10.1101/226639 Cold Spring Harbor Laboratory Press 2017-11-29 <![CDATA[ Gating by induced α-γ asynchrony in selective attention ]]> https://biorxiv.org/content/10.1101/229526v1?rss=1 Pascucci, D. Hervais-Adelman, A. Michel, C. Plomp, G. 2017-12-05 doi:10.1101/229526 Cold Spring Harbor Laboratory Press 2017-12-05 <![CDATA[ Examination of the Shared Genetic Basis of Anorexia Nervosa and Obsessive-Compulsive Disorder ]]> https://biorxiv.org/content/10.1101/231076v1?rss=1 Yilmaz, Z. Halvorsen, M. Bryois, J. Yu, D. Eating Disorders Working Group of the PGC, Tourette Syndrome/OCD Working Group of the PGC, Thornton, L. M. Zerwas, S. Micali, N. Moessner, R. Burton, C. L. Zai, G. Erdman, L. Kas, M. J. Arnold, P. D. Davis, L. K. Knowles, J. A. Breen, G. Scharf, J. M. Nestadt, G. Mathews, C. A. Bulik, C. M. Mattheisen, M. Crowley, J. J. 2017-12-08 doi:10.1101/231076 Cold Spring Harbor Laboratory Press 2017-12-08 <![CDATA[ ACI-1 class A beta-lactamase is widespread across human gut microbiomes due to transposons harboured by tailed prophages ]]> https://biorxiv.org/content/10.1101/235788v1?rss=1 Rands, C. M. Starikova, E. V. Brüssow, H. Kriventseva, E. V. Govorun, V. M. Zdobnov, E. M. 2017-12-18 doi:10.1101/235788 Cold Spring Harbor Laboratory Press 2017-12-18 <![CDATA[ Deficient autophagy drives aging in Hydra ]]> https://biorxiv.org/content/10.1101/236638v1?rss=1 TOMCZYK, S. SCHENKELAARS, Q. SUKNOVIC, N. WENGER, Y. EKUNDAYO, K. BUZGARIU, W. BAUER, C. FISCHER, K. E. AUSTAD, S. GALLIOT, B. 2017-12-23 doi:10.1101/236638 Cold Spring Harbor Laboratory Press 2017-12-23 <![CDATA[ Measurement of the mapping between intracranial EEG and fMRI recordings in the human brain ]]> https://biorxiv.org/content/10.1101/237198v1?rss=1 Carmichael, D. W. Vulliemoz, S. Murta, T. Chaudhary, U. Perani, S. Rodionov, R. Rosa, M. M. Friston, K. Lemieux, L. 2017-12-21 doi:10.1101/237198 Cold Spring Harbor Laboratory Press 2017-12-21 <![CDATA[ A genome-wide association study for shared risk across major psychiatric disorders in a nation-wide birth cohort implicates fetal neurodevelopment as a key mediator ]]> https://biorxiv.org/content/10.1101/240911v1?rss=1 Schork, A. J. Won, H. Appadurai, V. Nudel, R. Gandal, M. Delaneau, O. Hougaard, D. Baekved-Hansen, M. Bybjerg-Grauholm, J. Pedersen, M. G. Pedersen, C. B. Neale, B. M. Daly, M. J. Nordentoft, M. Mors, O. Boerglum, A. D. Mortensen, P. B. Buil, A. Thompson, W. K. Geschwind, D. Werge, T. 2017-12-29 doi:10.1101/240911 Cold Spring Harbor Laboratory Press 2017-12-29 <![CDATA[ Learning optimal decisions with confidence ]]> https://biorxiv.org/content/10.1101/244269v1?rss=1 Drugowitsch, J. Pouget, A. 2018-01-07 doi:10.1101/244269 Cold Spring Harbor Laboratory Press 2018-01-07 <![CDATA[ Green function of correlated genes and themechanical evolution of protein ]]> https://biorxiv.org/content/10.1101/246082v1?rss=1 Dutta, S. Eckmann, J.-P. Libchaber, A. Tlusty, T. 2018-01-10 doi:10.1101/246082 Cold Spring Harbor Laboratory Press 2018-01-10 <![CDATA[ Navigating in vitro bioactivity data: investigating available resources using model compounds ]]> https://biorxiv.org/content/10.1101/248898v1?rss=1 Ilmjarv, S. Augsburger, F. Bolleman, J. T. Liechti, R. Bridge, A. Sandstrom, J. Jaquet, V. Xenarios, I. Krause, K.-H. 2018-01-17 doi:10.1101/248898 Cold Spring Harbor Laboratory Press 2018-01-17 <![CDATA[ Genomic dissection of Systemic Lupus Erythematosus: Distinct Susceptibility, Activity and Severity Signatures ]]> https://biorxiv.org/content/10.1101/255109v1?rss=1 Panousis, N. I. Bertsias, G. Ongen, H. Gergianaki, I. Tektonidou, M. Trachana, M. Romano-Palumbo, L. Bielser, D. Howald, C. Pamfil, C. Fanouriakis, A. Kosmara, D. Repa, A. Sidiropoulos, P. Dermitzakis, E. T. Boumpas, D. T. 2018-01-27 doi:10.1101/255109 Cold Spring Harbor Laboratory Press 2018-01-27 <![CDATA[ Mechanistic analysis of the SERK3 elongated allele defines a role for BIR ectodomains in brassinosteroid signaling ]]> https://biorxiv.org/content/10.1101/257543v1?rss=1 Hohmann, U. Nicolet, J. Moretti, A. Hothorn, L. A. Hothorn, M. 2018-01-31 doi:10.1101/257543 Cold Spring Harbor Laboratory Press 2018-01-31 <![CDATA[ Imposing a curfew on the use of screen electronic devices improves sleep and daytime vigilance in adolescents. ]]> https://biorxiv.org/content/10.1101/259309v1?rss=1 Perrault, A. A. Bayer, L. Peuvrier, M. Afyouni, A. Ghisletta, P. Perrig, S. Schwartz, S. Sterpenich, V. 2018-02-07 doi:10.1101/259309 Cold Spring Harbor Laboratory Press 2018-02-07 <![CDATA[ Frequency selective encoding of substrate vibrations in the somatosensory cortex ]]> https://biorxiv.org/content/10.1101/264747v1?rss=1 Prsa, M. Huber, D. 2018-02-14 doi:10.1101/264747 Cold Spring Harbor Laboratory Press 2018-02-14 <![CDATA[ The intestinal microbiota predisposes to traveller’s diarrhoea and to the carriage of multidrug-resistant Enterobacteriaceae after travelling to tropical regions ]]> https://biorxiv.org/content/10.1101/265033v1?rss=1 Leo, S. Lazarevic, V. Gaia, N. Estellat, C. Girard, M. Matheron, S. Armand-Lefevre, L. Andremont, A. The VOYAG-R Study Group, Schrenzel, J. Ruppe, E. 2018-02-14 doi:10.1101/265033 Cold Spring Harbor Laboratory Press 2018-02-14 <![CDATA[ An evolutionary-conserved Wnt3/β-catenin/Sp5 feedback loop restricts head organizer activity in Hydra ]]> https://biorxiv.org/content/10.1101/265785v1?rss=1 Vogg, M. C. Beccari, L. Iglesias Olle, L. Rampon, C. Vriz, S. Perruchoud, C. Wenger, Y. Galliot, B. 2018-02-14 doi:10.1101/265785 Cold Spring Harbor Laboratory Press 2018-02-14 <![CDATA[ Rab-mediated trafficking in the secondary cells of Drosophila male accessory glands and its role in fecundity ]]> https://biorxiv.org/content/10.1101/266353v1?rss=1 Prince, E. Brankatschk, M. Kroeger, B. Wilson, C. Gligorov, D. Eaton, S. Karch, F. Maeda, R. K. 2018-02-15 doi:10.1101/266353 Cold Spring Harbor Laboratory Press 2018-02-15 <![CDATA[ LimeSeg: A coarsed-grained lipid membrane simulation for 3D image segmentation ]]> https://biorxiv.org/content/10.1101/267534v1?rss=1 Machado, S. Mercier, V. Chiaruttini, N. 2018-02-18 doi:10.1101/267534 Cold Spring Harbor Laboratory Press 2018-02-18 <![CDATA[ Pervasive transcription-dependent chromatin remodeling influences the replication initiation program ]]> https://biorxiv.org/content/10.1101/272666v1?rss=1 Soudet, J. Kaur, J. Stutz, F. 2018-02-27 doi:10.1101/272666 Cold Spring Harbor Laboratory Press 2018-02-27 <![CDATA[ Avoiding sedentary behaviors requires more cortical resources than avoiding physical activity: An EEG study ]]> https://biorxiv.org/content/10.1101/277988v1?rss=1 Cheval, B. Tipura, E. Burra, N. Frossard, J. Chanal, J. Orsholits, D. Radel, R. Boisgontier, M. P. 2018-03-07 doi:10.1101/277988 Cold Spring Harbor Laboratory Press 2018-03-07 <![CDATA[ Neuronal signature of social novelty exploration in the VTA: implication for Autism Spectrum Disorder ]]> https://biorxiv.org/content/10.1101/280537v1?rss=1 Bariselli, S. Hornberg, H. Prevost-Solie, C. Musardo, S. Hatstatt-Burkle, L. Scheiffele, P. Bellone, C. 2018-03-12 doi:10.1101/280537 Cold Spring Harbor Laboratory Press 2018-03-12 <![CDATA[ Higher-order thalamocortical inputs gate synaptic long-term potentiation via disinhibiton ]]> https://biorxiv.org/content/10.1101/281477v1?rss=1 Williams, L. E. Holtmaat, A. 2018-03-20 doi:10.1101/281477 Cold Spring Harbor Laboratory Press 2018-03-20 <![CDATA[ TFAP2 transcription factors are regulators of lipid droplet biogenesis ]]> https://biorxiv.org/content/10.1101/282376v1?rss=1 Scott, C. C. Vossio, S. Rougemont, J. Gruenberg, J. 2018-03-14 doi:10.1101/282376 Cold Spring Harbor Laboratory Press 2018-03-14 <![CDATA[ In vivo pulse-labeling of isochronic cohorts of cells in the central nervous system using FlashTag ]]> https://biorxiv.org/content/10.1101/286831v1?rss=1 Govindan, S. Oberst, P. Jabaudon, D. 2018-03-22 doi:10.1101/286831 Cold Spring Harbor Laboratory Press 2018-03-22 <![CDATA[ Symbiosis-related genes sustain the development of a downy mildew pathogen on Arabidopsis thaliana ]]> https://biorxiv.org/content/10.1101/286872v1?rss=1 Ried, M. K. Banhara, A. Binder, A. Hwu, F.-H. Gust, A. A. Höfle, C. Hückelhoven, R. Nürnberger, T. Parniske, M. 2018-03-22 doi:10.1101/286872 Cold Spring Harbor Laboratory Press 2018-03-22 <![CDATA[ A translaminar genetic logic for the circuit identity of intracortically-projecting neurons ]]> https://biorxiv.org/content/10.1101/290395v1?rss=1 Klingler, E. De la Rossa, A. Fievre, S. Jabaudon, D. 2018-03-28 doi:10.1101/290395 Cold Spring Harbor Laboratory Press 2018-03-28 <![CDATA[ Discovery of biomarkers for glycaemic deterioration before and after the onset of type 2 diabetes: an overview of the data from the epidemiological studies within the IMI DIRECT Consortium ]]> https://biorxiv.org/content/10.1101/300244v1?rss=1 Koivula, R. W. Forgie, I. M. Kurbasic, A. Vinuela, A. Heggie, A. Giordano, G. N. Hansen, T. H. Hudson, M. Koopman, A. Rutters, F. Siloaho, M. Allin, K. H. Brage, S. Brorsson, C. A. Dawed, A. Y. De Masi, F. Groves, C. J. Kokkola, T. Mahajan, A. Perry, M. H. Rauh, S. P. Ridderstrale, M. Teare, H. J. Thomas, E. L. Tura, A. Vestergaard, H. White, T. Adamski, J. Bell, J. D. Brunak, S. Dekker, J. Dermitzakis, E. T. Froguel, P. Frost, G. Gupta, R. Torben, H. Hattersley, A. Jablonka, B. Laakso, M. McDonald, T. J. Pedersen, O. Schwenk, J. M. Pavo, I. Mari, A. 2018-04-16 doi:10.1101/300244 Cold Spring Harbor Laboratory Press 2018-04-16 <![CDATA[ Thrombocytopenia Microcephaly Syndrome - a novel phenotype associated with ACTB mutations ]]> https://biorxiv.org/content/10.1101/303909v1?rss=1 Latham, S. L. Ehmke, N. Reinke, P. Y. A. Taft, M. H. Lyons, M. J. Friez, M. J. Lee, J. A. Hecker, R. Fruehwald, M. C. Becker, K. Neuhann, T. M. Horn, D. Schrock, E. Sarnow, K. Gruetzmann, K. Gawehn, L. Klink, B. Rump, A. Chaponnier, C. Knoefler, R. Manstein, D. J. Di Donato, N. 2018-04-18 doi:10.1101/303909 Cold Spring Harbor Laboratory Press 2018-04-18 <![CDATA[ Genomic, Proteomic and Phenotypic Heterogeneity in HeLa Cells across Laboratories: Implications for Reproducibility of Research Results ]]> https://biorxiv.org/content/10.1101/307421v1?rss=1 Liu, Y. Mi, Y. Mueller, T. Kreibich, S. Williams, E. G. Van Drogen, A. Borel, C. Germain, P.-L. Frank, M. Bludau, I. Mehnert, M. Seifert, M. Emmenlauer, M. Sorg, I. Bezrukov, F. Bena, F. S. Zhou, H. Dehio, C. Testa, G. Saez-Rodriguez, J. Antonarakis, S. E. Hardt, W.-D. Aebersold, R. 2018-04-30 doi:10.1101/307421 Cold Spring Harbor Laboratory Press 2018-04-30 <![CDATA[ Imaging beyond the super-resolution limits using ultrastructure expansion microscopy (UltraExM) ]]> https://biorxiv.org/content/10.1101/308270v1?rss=1 Gambarotto, D. Zwettler, F. Cernohorska, M. Fortun, D. Borgers, S. Heine, J. Schloetel, J.-G. Reuss, M. Unser, M. Boyden, E. Sauer, M. Hamel, V. Guichard, P. 2018-04-25 doi:10.1101/308270 Cold Spring Harbor Laboratory Press 2018-04-25 <![CDATA[ Optical alignment device for two-photon microscopy ]]> https://biorxiv.org/content/10.1101/312207v1?rss=1 Galinanes, G. Marchand, P. J. Turcotte, R. Pellat, S. Ji, N. Huber, D. 2018-05-01 doi:10.1101/312207 Cold Spring Harbor Laboratory Press 2018-05-01 <![CDATA[ Single-cell mRNA profiling reveals heterogeneous combinatorial expression of Hoxd genes during limb development ]]> https://biorxiv.org/content/10.1101/327619v1?rss=1 Fabre, P. J. Leleu, M. Mascrez, B. Lo Giudice, Q. Cobb, J. Duboule, D. 2018-05-22 doi:10.1101/327619 Cold Spring Harbor Laboratory Press 2018-05-22 <![CDATA[ General Regulatory Factors control the fidelity of transcription by restricting non-coding and ectopic initiation ]]> https://biorxiv.org/content/10.1101/331793v1?rss=1 Challal, D. Barucco, M. Kubik, S. Feuerbach, F. Candelli, T. Geoffroy, H. Benaksas, C. Shore, D. Libri, D. 2018-05-26 doi:10.1101/331793 Cold Spring Harbor Laboratory Press 2018-05-26 <![CDATA[ ESCRT and autophagy cooperate to repair ESX-1-dependent damage to the Mycobacterium-containing vacuole ]]> https://biorxiv.org/content/10.1101/334755v1?rss=1 Lopez-Jimenez, A. T. Cardenal Munoz, E. Leuba, F. Gerstenmaier, L. Hagedorn, M. King, J. S. Soldati, T. 2018-05-30 doi:10.1101/334755 Cold Spring Harbor Laboratory Press 2018-05-30 <![CDATA[ Hook length of the bacterial flagellum is controlled to nanometer-scale for optimal motility performance ]]> https://biorxiv.org/content/10.1101/336602v1?rss=1 Spöring, I. Martinez, V. A. Hotz, C. Schwarz-Linek, J. Grady, K. L. Nava-Sedeno, J. M. Vissers, T. Singer, H. M. Rohde, M. Bourquin, C. Hatzikirou, H. Poon, W. C. Dufour, Y. Erhardt, M. 2018-06-02 doi:10.1101/336602 Cold Spring Harbor Laboratory Press 2018-06-02 <![CDATA[ SHANK3 downregulation in the VTA accelerates the extinction of contextual associations induced by non-familiar conspecific interaction ]]> https://biorxiv.org/content/10.1101/342295v1?rss=1 Bariselli, S. Contestabile, A. Tzanoulinou, S. Bellone, C. 2018-06-08 doi:10.1101/342295 Cold Spring Harbor Laboratory Press 2018-06-08 <![CDATA[ PIKfyve/Fab1 is required for efficient V-ATPase delivery to phagosomes, phagosomal killing, and restriction of Legionella infection ]]> https://biorxiv.org/content/10.1101/343301v1?rss=1 Buckley, C. M. Heath, V. L. Gueho, A. Dove, S. K. Michell, R. H. Meier, R. Hilbi, H. Soldati, T. Insall, R. H. King, J. 2018-06-09 doi:10.1101/343301 Cold Spring Harbor Laboratory Press 2018-06-09 <![CDATA[ Capturing the spatiotemporal dynamics of task-initiated thoughts with combined EEG and fMRI ]]> https://biorxiv.org/content/10.1101/346346v1?rss=1 Brechet, L. Brunet, D. Birot, G. Gruetter, R. Michel, C. M. Jorge, J. 2018-06-14 doi:10.1101/346346 Cold Spring Harbor Laboratory Press 2018-06-14 <![CDATA[ Maternal group 2 innate lymphoid cells control fetal growth and protect from endotoxin-induced abortion in mice ]]> https://biorxiv.org/content/10.1101/348755v1?rss=1 Balmas, E. Rana, B. M. Hamilton, R. S. Shreeve, N. Kieckbusch, J. Aye, I. Hawkes, D. A. Trotter, S. Lopez-Trello, J. Yong, H. E. Valenti, S. Sferruzzi-Perri, A. N. Gaccioli, F. McKenzie, A. N. Colucci, F. 2018-06-16 doi:10.1101/348755 Cold Spring Harbor Laboratory Press 2018-06-16 <![CDATA[ Similarity and strength of glomerular odor representations define neural metric of sniff-invariant discrimination time ]]> https://biorxiv.org/content/10.1101/356279v1?rss=1 Abraham, N. M. Konakamchi, S. Bhattacharjee, A. S. Turaev, D. Vincis, R. Nunes, D. Spors, H. Carleton, A. Kuner, T. 2018-06-27 doi:10.1101/356279 Cold Spring Harbor Laboratory Press 2018-06-27 <![CDATA[ Think zinc: Role of zinc poisoning in the intraphagosomal killing of bacteria by the amoeba Dictyostelium ]]> https://biorxiv.org/content/10.1101/356949v1?rss=1 Barisch, C. Kalinina, V. Lefrancois, L. H. Appiah, J. Soldati, T. 2018-06-27 doi:10.1101/356949 Cold Spring Harbor Laboratory Press 2018-06-27 <![CDATA[ Transposon silencing in the Drosophila female germline ensures genome stability in progeny embryos ]]> https://biorxiv.org/content/10.1101/363028v1?rss=1 Ephrussi, A. Durdevic, Z. Pillai, R. S. 2018-07-05 doi:10.1101/363028 Cold Spring Harbor Laboratory Press 2018-07-05 <![CDATA[ Curvature Dependent constraints drive remodeling of epithelia ]]> https://biorxiv.org/content/10.1101/364208v1?rss=1 Maechler, F. Allier, C. Roux, A. Tomba, C. 2018-07-08 doi:10.1101/364208 Cold Spring Harbor Laboratory Press 2018-07-08 <![CDATA[ Synchronised brood transport by ants occurs without communication ]]> https://biorxiv.org/content/10.1101/364273v1?rss=1 Mersch, D. P. Eckmann, J.-P. Crespi, A. Keller, L. 2018-07-08 doi:10.1101/364273 Cold Spring Harbor Laboratory Press 2018-07-08 <![CDATA[ Expression estimation and eQTL mapping for HLA genes with a personalized pipeline ]]> https://biorxiv.org/content/10.1101/365957v1?rss=1 Aguiar, V. R. C. Cesar, J. E. Delaneau, O. Dermitzakis, E. T. Meyer, D. 2018-07-10 doi:10.1101/365957 Cold Spring Harbor Laboratory Press 2018-07-10 <![CDATA[ Simultaneous production of diverse neuronal subtypes during early corticogenesis ]]> https://biorxiv.org/content/10.1101/369678v1?rss=1 Magrinelli, E. Wagener, R. J. Jabaudon, D. 2018-07-16 doi:10.1101/369678 Cold Spring Harbor Laboratory Press 2018-07-16 <![CDATA[ CONSERVATION AND VARIATIONS OF BIMODAL HoxD GENE REGULATION DURING TETRAPOD LIMB DEVELOPMENT ]]> https://biorxiv.org/content/10.1101/372664v1?rss=1 Yakushiji-Kaminatsui, N. Lopez-Delisle, L. Bolt, C. C. Andrey, G. Beccari, L. Duboule, D. 2018-07-19 doi:10.1101/372664 Cold Spring Harbor Laboratory Press 2018-07-19 <![CDATA[ Single-cell molecular connectomics of intracortically-projecting neurons ]]> https://biorxiv.org/content/10.1101/378760v1?rss=1 Klingler, E. Prados, J. Kebschull, J. M. Dayer, A. Zador, A. M. Jabaudon, D. 2018-07-27 doi:10.1101/378760 Cold Spring Harbor Laboratory Press 2018-07-27 <![CDATA[ High efficiency genomic editing in Epstein-Barr virus-transformed lymphoblastoid B cells. ]]> https://biorxiv.org/content/10.1101/379461v1?rss=1 Johnston, A. D. Simoes-Pires, C. Suzuki, M. Greally, J. 2018-07-29 doi:10.1101/379461 Cold Spring Harbor Laboratory Press 2018-07-29 <![CDATA[ The Genomic Basis of Arthropod Diversity ]]> https://biorxiv.org/content/10.1101/382945v1?rss=1 Thomas, G. W. C. Dohmen, E. Hughes, D. S. T. Murali, S. C. Poelchau, M. Glastad, K. Anstead, C. A. Ayoub, N. A. Batterham, P. Bellair, M. Binford, G. J. Chao, H. Chen, Y. H. Childers, C. Dinh, H. Doddapaneni, H. Duan, J. J. Dugan, S. Esposito, L. A. Friedrich, M. Garb, J. Gasser, R. B. B. Goodisman, M. A. D. Gundersen-Rindal, D. E. Han, Y. Handler, A. M. Hatakeyama, M. Hering, L. Hunter, W. B. Ioannidis, P. Jayaseelan, J. C. Kalra, D. Khila, A. Korhonen, P. K. Lee, C. E. Lee, S. L. Li, Y. Lindsey, A. R. I. Mayer, G. McGregor, A. P. McKenna, D. D. Misof, 2018-08-04 doi:10.1101/382945 Cold Spring Harbor Laboratory Press 2018-08-04 <![CDATA[ Dopamine neurons projecting to medial shell of the nucleus accumbens drive heroin reinforcement ]]> https://biorxiv.org/content/10.1101/385039v1?rss=1 Lüscher, C. Corre, J. Tian, L. Patriarchi, T. Loureïro, M. Pascoli, V. van Zessen, R. 2018-08-04 doi:10.1101/385039 Cold Spring Harbor Laboratory Press 2018-08-04 <![CDATA[ Assessment of Menstrual Health Status and Evolution through Mobile Apps for Fertility Awareness ]]> https://biorxiv.org/content/10.1101/385054v1?rss=1 Symul, L. Wac, K. Hillard, P. Salathe, M. 2018-08-15 doi:10.1101/385054 Cold Spring Harbor Laboratory Press 2018-08-15 <![CDATA[ Aurora A depletion reveals centrosome-independent polarization mechanism in C. elegans ]]> https://biorxiv.org/content/10.1101/388918v1?rss=1 Klinkert, K. Levernier, N. Gross, P. Gentili, C. von Tobel, L. Pierron, M. Busso, C. Herrman, S. Grill, S. W. Kruse, K. Gonczy, P. 2018-08-09 doi:10.1101/388918 Cold Spring Harbor Laboratory Press 2018-08-09 <![CDATA[ Detecting overlapping spatial clusters of high sugar-sweetened beverage intake and high body mass index in a general population: a cross-sectional study ]]> https://biorxiv.org/content/10.1101/399584v1?rss=1 Joost, S. De Ridder, D. Marques-Vidal, P. Bacchilega, B. Theler, J.-M. Gaspoz, J.-M. Guessous, I. 2018-08-29 doi:10.1101/399584 Cold Spring Harbor Laboratory Press 2018-08-29 <![CDATA[ Genomic signatures accompanying the dietary shift to phytophagy in polyphagous beetles ]]> https://biorxiv.org/content/10.1101/399808v1?rss=1 Seppey, M. Ioannidis, P. Emerson, B. C. Pitteloud, C. Robinson-Rechavi, M. Roux, J. Escalona, H. E. McKenna, D. D. Misof, B. Shin, S. Zhou, X. Waterhouse, R. M. Alvarez, N. 2018-08-26 doi:10.1101/399808 Cold Spring Harbor Laboratory Press 2018-08-26 <![CDATA[ Human pancreatic islet 3D chromatin architecture provides insights into the genetics of type 2 diabetes ]]> https://biorxiv.org/content/10.1101/400291v1?rss=1 Miguel-Escalada, I. Bonas-Guarch, S. Cebola, I. Ponsa-Cobas, J. Mendieta-Esteban, J. Rolando, D. M. Y. Javierre, B. M. Atla, G. Farabella, I. Morgan, C. C. Garcia-Hurtado, J. Beucher, A. Moran, I. Pasquali, L. Ramos, M. Appel, E. V. R. Linneberg, A. Gjesing, A. P. Witte, D. R. Pedersen, O. Garup, N. Ravassard, P. Torrents, D. Mercader, J. M. Piemonti, L. Berney, T. de Koning, E. J. P. Kerr-Conte, J. Pattou, F. Fedko, I. O. Prokopenko, I. Hansen, T. Marti-Renom, M. A. Fraser, P. Ferrer, J. 2018-08-27 doi:10.1101/400291 Cold Spring Harbor Laboratory Press 2018-08-27 <![CDATA[ Cyclodextrin triggers MCOLN1-dependent endo-lysosome secretion in Niemann-Pick type C cells ]]> https://biorxiv.org/content/10.1101/401190v1?rss=1 Vacca, F. Vossio, S. Mercier, V. Moreau, D. Johnson, S. Paz Montoya, J. Moniatte, M. Gruenberg, J. 2018-08-27 doi:10.1101/401190 Cold Spring Harbor Laboratory Press 2018-08-27 <![CDATA[ Extrinsic and Intrinsic Dynamics in Movement Intermittency ]]> https://biorxiv.org/content/10.1101/402552v1?rss=1 Susilaradeya, D. Xu, W. Hall, T. M. Galan, F. Alter, K. Jackson, A. 2018-08-29 doi:10.1101/402552 Cold Spring Harbor Laboratory Press 2018-08-29 <![CDATA[ In vivo function of the lipid raft protein Flotillin 1 during CD8+ T cell-mediated host surveillance ]]> https://biorxiv.org/content/10.1101/403592v1?rss=1 Ficht, X. Ruef, N. Stolp, B. Moalli, F. Page, N. Merkler, D. Nichols, B. J. Diz-Munoz, A. Niggli, V. Stein, J. 2018-08-29 doi:10.1101/403592 Cold Spring Harbor Laboratory Press 2018-08-29 <![CDATA[ Profound functional and molecular diversity of mitochondria revealed by cell type-specific profiling in vivo ]]> https://biorxiv.org/content/10.1101/403774v1?rss=1 Fecher, C. Trovo, L. Müller, S. A. Snaidero, N. Wettmarshausen, J. Heink, S. Ortiz, O. Wagner, I. Kühn, R. Hartmann, J. Karl, R. M. Konnerth, A. Korn, T. Wurst, W. Merkler, D. Lichtenthaler, S. L. Perocchi, F. Misgeld, T. 2018-08-29 doi:10.1101/403774 Cold Spring Harbor Laboratory Press 2018-08-29 <![CDATA[ VTA dopamine neurons multiplex external with internal representations of goal-directed action ]]> https://biorxiv.org/content/10.1101/408062v1?rss=1 Kremer, Y. Flakowski, J. Rohner, C. Lüscher, C. 2018-09-04 doi:10.1101/408062 Cold Spring Harbor Laboratory Press 2018-09-04 <![CDATA[ Single-cell transcriptional dynamics and origins of neuronal diversity in the developing mouse neocortex ]]> https://biorxiv.org/content/10.1101/409458v1?rss=1 Telley, L. Agirman, G. Prados, J. Fievre, S. Oberst, P. Vitali, I. Nguyen, L. Dayer, A. Jabaudon, D. 2018-09-06 doi:10.1101/409458 Cold Spring Harbor Laboratory Press 2018-09-06 <![CDATA[ Single-cell transcriptomics of the mouse gonadal soma reveals the establishment of sexual dimorphism in distinct cell lineages ]]> https://biorxiv.org/content/10.1101/410407v1?rss=1 Stevant, I. Kuhne, F. Greenfield, A. Chaboissier, M.-C. Dermitzakis, E. T. Nef, S. 2018-09-07 doi:10.1101/410407 Cold Spring Harbor Laboratory Press 2018-09-07 <![CDATA[ Drug-induced increase in lysobisphosphatidic acid reduces the cholesterol overload in Niemann-Pick type C cells and mice ]]> https://biorxiv.org/content/10.1101/416479v1?rss=1 Moreau, D. Vacca, F. Vossio, S. Scott, C. C. Colaco, A. Paz Montoya, J. Ferguson, C. Moniatte, M. Parton, R. G. Platt, F. M. Gruenberg, J. 2018-09-13 doi:10.1101/416479 Cold Spring Harbor Laboratory Press 2018-09-13 <![CDATA[ Sfp1 regulates transcriptional networks driving cell growth and division through multiple promoter binding modes ]]> https://biorxiv.org/content/10.1101/420794v1?rss=1 Shore, D. Albert, B. Tomassetti, S. Gloor, Y. Dilg, D. Mattarocci, S. Kubik, S. 2018-09-18 doi:10.1101/420794 Cold Spring Harbor Laboratory Press 2018-09-18 <![CDATA[ Anoxygenic Photosynthesis and Dark Carbon Metabolism under micro-oxic conditions in the Purple Sulfur Bacterium \"Thiodictyon syntrophicum\" nov. strain Cad16T ]]> https://biorxiv.org/content/10.1101/420927v1?rss=1 Luedin, S. M. Storelli, N. Danza, F. Roman, S. Wittwer, M. Pothier, J. F. Tonolla, M. 2018-09-18 doi:10.1101/420927 Cold Spring Harbor Laboratory Press 2018-09-18 <![CDATA[ Time and space dimensions of gene dosage imbalance of aneuploidies revealed by single cell transcriptomes. ]]> https://biorxiv.org/content/10.1101/424887v1?rss=1 Stamoulis, G. Garieri, M. Makrythanasis, P. Letourneau, A. Guipponi, M. Panousis, N. Sloan-Bena, F. Falconnet, E. Ribaux, P. Borel, C. Santoni, F. A. Antonarakis, S. E. 2018-09-23 doi:10.1101/424887 Cold Spring Harbor Laboratory Press 2018-09-23 <![CDATA[ The mRNA export adaptor Yra1 contributes to DNA double-strand break repair through its C-box domain ]]> https://biorxiv.org/content/10.1101/441980v1?rss=1 Stutz, F. Infantino, V. Tutucci, E. Yeh Martin, N. Zihlmann, A. Garcia-Molinero, V. Silvano, G. Palancade, B. 2018-10-12 doi:10.1101/441980 Cold Spring Harbor Laboratory Press 2018-10-12 <![CDATA[ Unraveling the polygenic architecture of complex traits using blood eQTL meta-analysis ]]> https://biorxiv.org/content/10.1101/447367v1?rss=1 Vosa, U. Claringbould, A. Westra, H.-J. Bonder, M. J. Deelen, P. Zeng, B. Kirsten, H. Saha, A. Kreuzhuber, R. Kasela, S. Pervjakova, N. Alvaes, I. Fave, M.-J. Agbessi, M. Christiansen, M. Jansen, R. Seppälä, I. Tong, L. Teumer, A. Schramm, K. Hemani, G. Verlouw, J. Yaghootkar, H. Sönmez, R. Andrew, A. A. Kukushkina, V. Kalnapenkis, A. Rüeger, S. Porcu, E. Kronberg-Guzman, J. Kettunen, J. Powell, J. Lee, B. Zhang, F. Arindrarto, W. Beutner, F. BIOS Consortium, Brugge, H. i2QTL Consortium, Dmitrieva, J. Elansary, M. Fairfax, B. P. Georges, M. He 2018-10-19 doi:10.1101/447367 Cold Spring Harbor Laboratory Press 2018-10-19 <![CDATA[ A stable, long-term cortical signature underlying consistent behavior ]]> https://biorxiv.org/content/10.1101/447441v1?rss=1 Gallego, J. A. Perich, M. G. Chowdhury, R. H. Solla, S. A. Miller, L. E. 2018-10-18 doi:10.1101/447441 Cold Spring Harbor Laboratory Press 2018-10-18 <![CDATA[ A chemogenetic approach for optical monitoring of voltage in neurons ]]> https://biorxiv.org/content/10.1101/463109v1?rss=1 Sundukova, M. Prifti, E. Bucci, A. Kirillova, K. Serrao, J. Reymond, L. Umebayashi, M. Hovius, R. Riezman, H. Johnsson, K. Heppenstall, P. A. 2018-11-06 doi:10.1101/463109 Cold Spring Harbor Laboratory Press 2018-11-06 <![CDATA[ Concurrent EEG- and fMRI-derived functional connectomes exhibit linked dynamics ]]> https://biorxiv.org/content/10.1101/464438v1?rss=1 Wirsich, J. Giraud, A.-L. Sadaghiani, S. 2018-11-07 doi:10.1101/464438 Cold Spring Harbor Laboratory Press 2018-11-07 <![CDATA[ Two bifunctional inositol pyrophosphate kinases/phosphatases control plant phosphate homeostasis. ]]> https://biorxiv.org/content/10.1101/467076v1?rss=1 Zhu, J. Lau, K. Harmel, R. K. Puschmann, R. Broger, L. Dutta, A. K. Jessen, H. J. Hothorn, L. A. Fiedler, D. Hothorn, M. 2018-11-09 doi:10.1101/467076 Cold Spring Harbor Laboratory Press 2018-11-09 <![CDATA[ Culling less fit neurons protects against amyloid-β induced brain damage and cognitive and motor decline ]]> https://biorxiv.org/content/10.1101/468868v1?rss=1 Coelho, D. S. Schwartz, S. Merino, M. M. Hauert, B. Topfel, B. Tieche, C. Rhiner, C. Moreno, E. 2018-11-13 doi:10.1101/468868 Cold Spring Harbor Laboratory Press 2018-11-13 <![CDATA[ Combining predictive coding with neural oscillations optimizes on-line speech processing ]]> https://biorxiv.org/content/10.1101/477588v1?rss=1 Hovsepyan, S. Olasagasti, I. Giraud, A.-L. 2018-11-27 doi:10.1101/477588 Cold Spring Harbor Laboratory Press 2018-11-27 <![CDATA[ Apical progenitors remain multipotent throughout corticalneurogenesis ]]> https://biorxiv.org/content/10.1101/478891v1?rss=1 Oberst, P. Fievre, S. Baumann, N. Concetti, C. Jabaudon, D. 2018-11-27 doi:10.1101/478891 Cold Spring Harbor Laboratory Press 2018-11-27 <![CDATA[ Integrating prediction errors at two time scales permits rapid recalibration of speech sound categories ]]> https://biorxiv.org/content/10.1101/479089v1?rss=1 Olasagasti, I. Giraud, A.-L. 2018-11-29 doi:10.1101/479089 Cold Spring Harbor Laboratory Press 2018-11-29 <![CDATA[ Widespread changes in firing rate and functional connectivity across the fronto-parietal network during rule guided working memory ]]> https://biorxiv.org/content/10.1101/479410v1?rss=1 Salazar, R. F. 2018-11-29 doi:10.1101/479410 Cold Spring Harbor Laboratory Press 2018-11-29 <![CDATA[ Neural Correlates of Optimal Multisensory Decision Making ]]> https://biorxiv.org/content/10.1101/480178v1?rss=1 Hou, H. Zheng, Q. Zhao, Y. Pouget, A. GU, Y. 2018-11-29 doi:10.1101/480178 Cold Spring Harbor Laboratory Press 2018-11-29 <![CDATA[ Coherence-based spectro-spatial fillters for stimulus features prediction from electrocorticographic recordings. ]]> https://biorxiv.org/content/10.1101/481572v1?rss=1 Delgado Saa, J. F. Christen, A. Martin, S. Pasley, B. N. Knight, R. T. Giraud, A.-L. 2018-11-28 doi:10.1101/481572 Cold Spring Harbor Laboratory Press 2018-11-28 <![CDATA[ Human online adaptation to changes in prior probability ]]> https://biorxiv.org/content/10.1101/483842v1?rss=1 Norton, E. H. Acerbi, L. Ma, W. J. Landy, M. S. 2018-11-30 doi:10.1101/483842 Cold Spring Harbor Laboratory Press 2018-11-30 <![CDATA[ Control of stem-cell niche establishment in Arabidopsis flowers by REVOLUTA and the LEAFY-RAX1 module ]]> https://biorxiv.org/content/10.1101/488114v1?rss=1 Denay, G. Tichtinsky, G. Le Masson, M. Chahtane, H. Huguet, S. Lopez-Vidriero, I. Wenzl, C. Franco-Zorrilla, J.-M. Simon, R. Lohmann, J. U. Parcy, F. 2018-12-06 doi:10.1101/488114 Cold Spring Harbor Laboratory Press 2018-12-06 <![CDATA[ Type-I myosins promote actin polymerization to drive membrane bending in endocytosis ]]> https://biorxiv.org/content/10.1101/490011v1?rss=1 Manenschijn, H. E. Picco, A. Mund, M. Ries, J. Kaksonen, M. 2018-12-09 doi:10.1101/490011 Cold Spring Harbor Laboratory Press 2018-12-09 <![CDATA[ Mechanistic insights into the evolution of DUF26-containing proteins in land plants ]]> https://biorxiv.org/content/10.1101/493502v1?rss=1 Vaattovaara, A. Brandt, B. Rajaraman, S. Safronov, O. Veidenberg, A. Luklova, M. Kangasjärvi, J. Löytynoja, A. Hothorn, M. Salojärvi, J. Wrzaczek, M. 2018-12-11 doi:10.1101/493502 Cold Spring Harbor Laboratory Press 2018-12-11 <![CDATA[ Identification of novel anti-bacterial compounds from a chemically highly diverse pathways-based library using phenotypic screens in amoebae host models ]]> https://biorxiv.org/content/10.1101/497032v1?rss=1 Kicka, S. Hanna, N. Chiriano, G. Harrison, C. Ouertatani Sakouhi, H. Trofimov, V. Kranjc, A. Hilbi, H. Cosson, P. Scapozza, L. Soldati, T. 2018-12-17 doi:10.1101/497032 Cold Spring Harbor Laboratory Press 2018-12-17 <![CDATA[ Transcriptional logic of cell fate specification and axon guidance in early born retinal neurons revealed by single-cell mRNA profiling ]]> https://biorxiv.org/content/10.1101/497081v1?rss=1 Lo Giudice, Q. Leleu, M. Fabre, P. J. 2018-12-14 doi:10.1101/497081 Cold Spring Harbor Laboratory Press 2018-12-14 <![CDATA[ The impact of learning on perceptual decisions and its implication for speed-accuracy tradeoffs ]]> https://biorxiv.org/content/10.1101/501858v1?rss=1 Mendonca, A. G. Drugowitsch, J. Vicente, M. I. DeWitt, E. Pouget, A. Mainen, Z. F. 2018-12-19 doi:10.1101/501858 Cold Spring Harbor Laboratory Press 2018-12-19 <![CDATA[ LEMMI: A Live Evaluation of Computational Methods for Metagenome Investigation ]]> https://biorxiv.org/content/10.1101/507731v1?rss=1 Seppey, M. Manni, M. Zdobnov, E. M. 2018-12-28 doi:10.1101/507731 Cold Spring Harbor Laboratory Press 2018-12-28 <![CDATA[ A contractile acto-myosin belt promotes growth anisotropy during the early stages of pectoral fin development in zebrafish. ]]> https://biorxiv.org/content/10.1101/512038v1?rss=1 Kardash, E. Nguyen, H. Behrndt, M. Heisenberg, C.-P. Peyrieras, N. Gonzalez-Gaitan, M. 2019-01-06 doi:10.1101/512038 Cold Spring Harbor Laboratory Press 2019-01-06 <![CDATA[ A ribosome assembly stress response regulates transcription to maintain proteome homeostasis ]]> https://biorxiv.org/content/10.1101/512665v1?rss=1 Albert, B. Kos-Braun, I. C. Henras, A. K. Dez, C. Rueda, M. P. Zhang, X. Gadal, O. Kos, M. Shore, D. 2019-01-06 doi:10.1101/512665 Cold Spring Harbor Laboratory Press 2019-01-06 <![CDATA[ Buckling of epithelium growing under spherical confinement ]]> https://biorxiv.org/content/10.1101/513119v1?rss=1 Trushko, A. Di Meglio, I. Merzouki, A. Blanch-Mercader, C. Abuhattum, S. Guck, J. Alessandri, K. Nassoy, P. Kruse, K. Chopard, B. Roux, A. 2019-01-07 doi:10.1101/513119 Cold Spring Harbor Laboratory Press 2019-01-07 <![CDATA[ The population dynamics of a canonical cognitive circuit ]]> https://biorxiv.org/content/10.1101/516021v1?rss=1 Chaudhuri, R. Gercek, B. Pandey, B. Peyrache, A. Fiete, I. 2019-01-09 doi:10.1101/516021 Cold Spring Harbor Laboratory Press 2019-01-09 <![CDATA[ Evolution of the mating type locus with suppressed recombination ]]> https://biorxiv.org/content/10.1101/518654v1?rss=1 Hadjivasiliou, Z. Pomiankowski, A. 2019-01-11 doi:10.1101/518654 Cold Spring Harbor Laboratory Press 2019-01-11 <![CDATA[ TORC2 Affects Endocytosis through Plasma Membrane Tension ]]> https://biorxiv.org/content/10.1101/520551v1?rss=1 Riggi, M. Macchione, M. Matile, S. Loewith, R. Roux, A. 2019-01-15 doi:10.1101/520551 Cold Spring Harbor Laboratory Press 2019-01-15 <![CDATA[ Local inhibition of PRC2 activity by H3.3K27M drives DNA replication defects through misregulation of the JNK pathway ]]> https://biorxiv.org/content/10.1101/525766v1?rss=1 Delaney, K. Strobino, M. Wenda, J. M. Pankowski, A. Steiner, F. A. 2019-01-21 doi:10.1101/525766 Cold Spring Harbor Laboratory Press 2019-01-21 <![CDATA[ Human discrimination and categorization of emotions in voices: a functional Near-Infrared Spectroscopy (fNIRS) study ]]> https://biorxiv.org/content/10.1101/526558v1?rss=1 Gruber, T. Debracque, C. Ceravolo, L. Igloi, K. Marin Bosch, B. Fruehholz, S. Grandjean, D. 2019-01-23 doi:10.1101/526558 Cold Spring Harbor Laboratory Press 2019-01-23 <![CDATA[ Preformed Chromatin Topology Assists TranscriptionalRobustness of Shh during Limb Development ]]> https://biorxiv.org/content/10.1101/528877v1?rss=1 Paliou, C. Guckelberger, P. Schöpflin, R. Heinrich, V. Esposito, A. Chiariello, A. M. M. Bianco, S. Annunziatella, C. Helmuth, J. Haas, S. Jerkovic, I. Brieske, N. Wittler, L. Timmermann, B. Nicodemi, M. Vingron, M. Mundlos, S. Andrey, G. 2019-01-23 doi:10.1101/528877 Cold Spring Harbor Laboratory Press 2019-01-23 <![CDATA[ Extinctions in marine plankton preceded by stabilizing selection ]]> https://biorxiv.org/content/10.1101/531947v1?rss=1 Weinkauf, M. F. G. Bonitz, F. G. W. Martini, R. Kucera, M. 2019-01-27 doi:10.1101/531947 Cold Spring Harbor Laboratory Press 2019-01-27 <![CDATA[ Fear in dreams and in wakefulness: evidence for day/night affective homeostasis ]]> https://biorxiv.org/content/10.1101/534099v1?rss=1 Sterpenich, V. Perogamvros, L. Tononi, G. Schwartz, S. 2019-01-29 doi:10.1101/534099 Cold Spring Harbor Laboratory Press 2019-01-29 <![CDATA[ The mechanistic basis for chromatin invasion and remodeling by the yeast pioneer transcription factor Rap1 ]]> https://biorxiv.org/content/10.1101/541284v1?rss=1 Mivelaz, M. Cao, A.-M. Kubik, S. Zencir, S. Hovius, R. Boichenko, I. Stachowicz, A. M. Kurat, C. F. Shore, D. Fierz, B. 2019-02-05 doi:10.1101/541284 Cold Spring Harbor Laboratory Press 2019-02-05 <![CDATA[ Transcriptome analysis of Plasmodium berghei during exo-erythrocytic development ]]> https://biorxiv.org/content/10.1101/543207v1?rss=1 Caldelari, R. Dogga, S. Schmid, M. W. Franke-Fayard, B. Janse, C. J. Soldati-Favre, D. Heussler, V. 2019-02-07 doi:10.1101/543207 Cold Spring Harbor Laboratory Press 2019-02-07 <![CDATA[ Deficit in motor skill learning-dependent synaptic plasticity at motor cortex to Dorso Lateral Striatum synapses in a mouse model of Huntington's disease ]]> https://biorxiv.org/content/10.1101/544718v1?rss=1 Glangetas, C. Espinosa, P. Bellone, C. 2019-02-08 doi:10.1101/544718 Cold Spring Harbor Laboratory Press 2019-02-08 <![CDATA[ ENDOSOMAL MEMBRANE TENSION CONTROLS ESCRT-III-DEPENDENT INTRA-LUMENAL VESICLE FORMATION ]]> https://biorxiv.org/content/10.1101/550483v1?rss=1 Roux, A. Gruenberg, J. Mercier, V. Larios, J. Goujon, A. Matile, S. Molinard, G. 2019-02-14 doi:10.1101/550483 Cold Spring Harbor Laboratory Press 2019-02-14 <![CDATA[ Large-scale brain network dynamics provide a measure of psychosis and anxiety in 22q11.2 deletion syndrome. ]]> https://biorxiv.org/content/10.1101/551796v1?rss=1 Zoeller, D. Sandini, C. Karahanoglu, F. I. Padula, M. C. Schaer, M. Eliez, S. Van De Ville, D. 2019-02-15 doi:10.1101/551796 Cold Spring Harbor Laboratory Press 2019-02-15 <![CDATA[ Centrosomes control kinetochore-fiber plus-end dynamics via HURP to ensure symmetric divisions ]]> https://biorxiv.org/content/10.1101/557058v1?rss=1 Dudka, D. Liaudet, N. Vassal, H. Meraldi, P. 2019-02-21 doi:10.1101/557058 Cold Spring Harbor Laboratory Press 2019-02-21 <![CDATA[ Basal protrusions mediate spatiotemporal patterns of spinal neuron differentiation ]]> https://biorxiv.org/content/10.1101/559195v1?rss=1 Hadjivasiliou, Z. Moore, R. McIntosh, R. Galea, G. Clarke, J. Alexandre, P. 2019-02-25 doi:10.1101/559195 Cold Spring Harbor Laboratory Press 2019-02-25 <![CDATA[ The Hsp70/Hsp90 Co-Chaperone Hop/Stip1 Shifts the Proteostatic Balance from Folding Towards Degradation ]]> https://biorxiv.org/content/10.1101/562637v1?rss=1 Bhattacharya, K. Weidenauer, L. Moran Luengo, T. Echeverria, P. C. Bernasconi, L. Wider, D. Villemin, M. Bauer, C. Rüdiger, S. G. D. Quadroni, M. Picard, D. 2019-02-27 doi:10.1101/562637 Cold Spring Harbor Laboratory Press 2019-02-27 <![CDATA[ Molecular characterization of CHAD domains as inorganic polyphosphate binding modules ]]> https://biorxiv.org/content/10.1101/567040v1?rss=1 Lorenzo-Orts, L. Hohmann, U. Zhu, J. Hothorn, M. 2019-03-04 doi:10.1101/567040 Cold Spring Harbor Laboratory Press 2019-03-04 <![CDATA[ Plant photoreceptors and their signaling components compete for binding to the ubiquitin ligase COP1 using their VP-peptide motifs ]]> https://biorxiv.org/content/10.1101/568618v1?rss=1 Lau, K. Podolec, R. Chappuis, R. Ulm, R. Hothorn, M. 2019-03-05 doi:10.1101/568618 Cold Spring Harbor Laboratory Press 2019-03-05 <![CDATA[ Constrained Transcriptional Polarity In The Organization Of Mammalian Hox Gene Clusters ]]> https://biorxiv.org/content/10.1101/572875v1?rss=1 Darbellay, F. Bochaton, C. Lopez-Delisle, L. Mascrez, B. Tschopp, P. Delpretti, S. Zakany, J. Duboule, D. 2019-03-11 doi:10.1101/572875 Cold Spring Harbor Laboratory Press 2019-03-11 <![CDATA[ Zinc intoxication of Mycobacterium marinum during Dictyostelium discoideum infection is counteracted by induction of the pathogen Zn2+ exporter CtpC ]]> https://biorxiv.org/content/10.1101/575217v1?rss=1 Lefrancois, L. H. Kalinina, V. Cardenal-Munoz, E. Hanna, N. Koliwer-Brandl, H. Appiah, J. Leuba, F. Hilbi, H. Soldati, T. Barisch, C. 2019-03-15 doi:10.1101/575217 Cold Spring Harbor Laboratory Press 2019-03-15 <![CDATA[ High-Affinity Binding of Chemokine Analogs that Display Ligand Bias at the HIV-1 Co-receptor CCR5 ]]> https://biorxiv.org/content/10.1101/575795v1?rss=1 Rico, C. A. Berchiche, Y. A. Horioka, M. Peeler, J. C. Lorenzen, E. Tian, H. Kazmi, M. A. Furstenberg, A. Gaertner, H. Hartley, O. Sakmar, T. P. Huber, T. 2019-03-16 doi:10.1101/575795 Cold Spring Harbor Laboratory Press 2019-03-16 <![CDATA[ The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast ]]> https://biorxiv.org/content/10.1101/575860v1?rss=1 Serbyn, N. Noireterre, A. Bagdiul, I. Plank, M. Michel, A. H. Loewith, R. Kornmann, B. Stutz, F. 2019-03-13 doi:10.1101/575860 Cold Spring Harbor Laboratory Press 2019-03-13 <![CDATA[ The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue ]]> https://biorxiv.org/content/10.1101/577122v1?rss=1 Voigt, F. Kirschenbaum, D. Platonova, E. Pages, S. Campbell, R. A. A. Kaestli, R. Schaettin, M. Egolf, L. van der Bourg, A. Bethge, P. Haenraets, K. Frezel, N. Topilko, T. Perin, P. Hillier, D. Hildebrand, S. Schueth, A. Roebroeck, A. Roska, B. Stoeckli, E. Pizzala, R. Renier, N. Zeilhofer, H. U. Karayannis, T. Ziegler, U. Batti, L. Holtmaat, A. Lüscher, C. Aguzzi, A. Helmchen, F. 2019-03-18 doi:10.1101/577122 Cold Spring Harbor Laboratory Press 2019-03-18 <![CDATA[ ZapA stabilizes FtsZ filament bundles without slowing down treadmilling dynamics ]]> https://biorxiv.org/content/10.1101/580944v1?rss=1 Caldas, P. Lopez-Pelegrin, M. Pearce, D. J. G. Budanur, N. B. Brugues, J. Loose, M. 2019-03-18 doi:10.1101/580944 Cold Spring Harbor Laboratory Press 2019-03-18 <![CDATA[ Crystal structure of the LRR ectodomain of the plant immune receptor kinase SOBIR1. ]]> https://biorxiv.org/content/10.1101/581231v1?rss=1 Hohmann, U. Hothorn, M. 2019-03-18 doi:10.1101/581231 Cold Spring Harbor Laboratory Press 2019-03-18 <![CDATA[ Dictyostelium discoideum flotillin homologues are essential for phagocytosis and participate in plasma membrane recycling and lysosome biogenesis ]]> https://biorxiv.org/content/10.1101/582049v1?rss=1 Bosmani, C. Bach, F. Leuba, F. Hanna, N. Burdet, F. Pagni, M. Hagedorn, M. Soldati, T. 2019-03-19 doi:10.1101/582049 Cold Spring Harbor Laboratory Press 2019-03-19 <![CDATA[ Nuclear pores as versatile reference standards for quantitative superresolution microscopy ]]> https://biorxiv.org/content/10.1101/582668v1?rss=1 Thevathasan, J. V. Kahnwald, M. Cieslinski, K. Hoess, P. Peneti, S. K. Reitberger, M. Heid, D. Kasuba, K. C. Hoerner, S. J. Li, Y. Wu, Y.-L. Mund, M. Matti, U. Pereira, P. M. Henriques, R. Nijmeijer-Winter, B. Kueblbeck, M. Jimenez Sabinina, V. Ellenberg, J. Ries, J. 2019-03-20 doi:10.1101/582668 Cold Spring Harbor Laboratory Press 2019-03-20 <![CDATA[ Integrin-dependent YAP signaling requires LAMTOR1 mediated delivery of Src to the plasma membrane ]]> https://biorxiv.org/content/10.1101/585349v1?rss=1 Bouvard, D. Block, M. Brunner, M. Ziegelmeyer, T. Lallemand, D. Pezet, M. Chevalier, G. Ronde, P. Wehrle-Haller, B. M. 2019-03-23 doi:10.1101/585349 Cold Spring Harbor Laboratory Press 2019-03-23 <![CDATA[ The genome of the blind soil-dwelling and ancestrally wingless dipluran Campodea augens, a key reference hexapod for studying the emergence of insect innovations ]]> https://biorxiv.org/content/10.1101/585695v1?rss=1 Manni, M. Simao, F. A. Robertson, H. M. Gabaglio, M. A. Waterhouse, R. M. Misof, B. Niehuis, O. Szucsich, N. Zdobnov, E. M. 2019-03-22 doi:10.1101/585695 Cold Spring Harbor Laboratory Press 2019-03-22 <![CDATA[ The developmental cycle of Dictyostelium discoideum ensures curing of a mycobacterial infection at both cell autonomous level and by collaborative exclusion ]]> https://biorxiv.org/content/10.1101/586263v1?rss=1 Lopez-Jimenez, A. T. Hagedorn, M. Delince, M. J. McKinney, J. Soldati, T. 2019-03-24 doi:10.1101/586263 Cold Spring Harbor Laboratory Press 2019-03-24 <![CDATA[ Generic and context-dependent gene modulations during Hydra whole body regeneration ]]> https://biorxiv.org/content/10.1101/587147v1?rss=1 Galliot, B. Wenger, Y. Buzgariu, W. Perruchoud, C. Loichot, G. 2019-03-24 doi:10.1101/587147 Cold Spring Harbor Laboratory Press 2019-03-24 <![CDATA[ IMPACT OF GENOME ARCHITECTURE UPON THE FUNCTIONAL ACTIVATION AND REPRESSION OF Hox REGULATORY LANDSCAPES ]]> https://biorxiv.org/content/10.1101/587303v1?rss=1 Rodriguez-Carballo, E. Lopez-Delisle, L. Yakushiji-Kaminatsui, N. Ullate-Agote, A. Duboule, D. 2019-03-23 doi:10.1101/587303 Cold Spring Harbor Laboratory Press 2019-03-23 <![CDATA[ Mitochondrial mutational spectrum provides an universal marker of cellular and organismal longevity ]]> https://biorxiv.org/content/10.1101/589168v1?rss=1 T substitutions, is typical only for the nuclear genome while it is extremely rare and age-independent in mtDNA. Thus it is still unclear if there is a mitochondria - specific mutational signature of the oxidative damage. Here, reconstructing mtDNA mutational spectra for human cancers originated from 21 tissues with various cell turnover rate, human oocytes fertilized at different ages, and 424 mammalian species with variable generation length which is a proxy for oocyte age, we observed that the frequency of AH>GH substitutions (H - heavy chain notation) is positively correlated with cellular and organismal longevity. Moreover, this mutational bias from AH to GH affects nucleotide content at the fourfold degenerative synonymous positions leading to a deficit of AH and excess of GH, which is especially pronounced in long-lived mammals. Taking into account additionally, that AH>GH is sensitive to time being single stranded during mtDNA asynchronous replication and A>G is associated with oxidative damage of single-stranded DNA in recent bacterial experiments we propose that AH>GH is a mutational signature of oxidative damage in mtDNA. ]]> Mikhaylova, A. G. Mikhailova, A. A. Ushakova, K. Tretyakov, E. Iurchenko, A. Zazhytska, M. Knorre, D. Zdobnov, E. Fleischmann, Z. Annis, S. Franco, M. Wasko, K. Kunz, W. Mazunin, I. Nikolaev, S. Reymond, A. Khrapko, K. Gunbin, K. Popadin, K. 2019-03-26 doi:10.1101/589168 Cold Spring Harbor Laboratory Press 2019-03-26 <![CDATA[ Time-resolved RNA-seq profiling of the infection of Dictyostelium discoideum by Mycobacterium marinum reveals an integrated host response to damage and stress ]]> https://biorxiv.org/content/10.1101/590810v1?rss=1 Hanna, N. Burdet, F. Melotti, A. Bosmani, C. Kicka, S. Hilbi, H. Cosson, P. Pagni, M. Soldati, T. 2019-03-27 doi:10.1101/590810 Cold Spring Harbor Laboratory Press 2019-03-27 <![CDATA[ Proteomic characterization of the Mycobacterium marinum-containing vacuole in Dictyostelium discoideum ]]> https://biorxiv.org/content/10.1101/592717v1?rss=1 Gueho, A. Bosmani, C. Soldati, T. 2019-03-28 doi:10.1101/592717 Cold Spring Harbor Laboratory Press 2019-03-28 <![CDATA[ Opposing chromatin remodelers control transcription initiation frequency and start site selection ]]> https://biorxiv.org/content/10.1101/592816v1?rss=1 Kubik, S. Challal, D. Bruzzone, M. J. Dreos, R. Mattarocci, S. Bucher, P. Libri, D. Shore, D. 2019-03-30 doi:10.1101/592816 Cold Spring Harbor Laboratory Press 2019-03-30 <![CDATA[ Treatment of mice with IL2-complex enhances inflammasome-driven IFN-γ production and prevents lethal toxoplasmosis ]]> https://biorxiv.org/content/10.1101/593574v1?rss=1 Kupz, A. Pai, S. Giacomin, P. R. Whan, J. A. Walker, R. Hammoudi, P.-M. Smith, N. Miller, C. M. 2019-03-29 doi:10.1101/593574 Cold Spring Harbor Laboratory Press 2019-03-29 <![CDATA[ Optimal policy for multi-alternative decisions ]]> https://biorxiv.org/content/10.1101/595843v1?rss=1 Tajima, S. Drugowitsch, J. Patel, N. Pouget, A. 2019-04-01 doi:10.1101/595843 Cold Spring Harbor Laboratory Press 2019-04-01 <![CDATA[ Phigaro: high throughput prophage sequence annotation ]]> https://biorxiv.org/content/10.1101/598243v1?rss=1 Starikova, E. V. Tikhonova, P. O. Prianichnikov, N. A. Rands, C. M. Zdobnov, E. M. Govorun, V. M. 2019-04-22 doi:10.1101/598243 Cold Spring Harbor Laboratory Press 2019-04-22 <![CDATA[ Socio-behavioural characteristics and HIV: findings from a causal modelling analysis of 29 sub-Saharan African countries ]]> https://biorxiv.org/content/10.1101/600510v1?rss=1 Baranczuk, Z. Estill, J. Blough, S. Meier, S. Merzouki, A. Maathuis, M. H. Keiser, O. 2019-04-12 doi:10.1101/600510 Cold Spring Harbor Laboratory Press 2019-04-12 <![CDATA[ Disruption of large-scale electrophysiological networks in stroke patients with visuospatial neglect ]]> https://biorxiv.org/content/10.1101/602318v1?rss=1 Ros, T. Michela, A. Meyer, A. Bellman, A. Vuadens, P. Zermatten, V. Saj, A. Vuilleumier, P. 2019-04-09 doi:10.1101/602318 Cold Spring Harbor Laboratory Press 2019-04-09 <![CDATA[ Comparative genomics groups phages of Negativicutes and classical Firmicutes despite different Gram-staining properties ]]> https://biorxiv.org/content/10.1101/606087v1?rss=1 Rands, C. M. Brussow, H. Zdobnov, E. M. 2019-04-11 doi:10.1101/606087 Cold Spring Harbor Laboratory Press 2019-04-11 <![CDATA[ Identifying microbial species by single-molecule DNA optical mapping and resampling statistics ]]> https://biorxiv.org/content/10.1101/609412v1?rss=1 Bouwens, A. Deen, J. Vitale, R. D'Huys, L. Goyvaerts, V. Descloux, A. Borrenberghs, D. Grussmayer, K. Lukes, T. Camacho, R. Su, J. Ruckebusch, C. Lasser, T. Van De Ville, D. Hofkens, J. Radenovic, A. Janssen, K. P. F. 2019-04-16 doi:10.1101/609412 Cold Spring Harbor Laboratory Press 2019-04-16 <![CDATA[ A bifunctional ATPase drives tad pilus extension and retraction ]]> https://biorxiv.org/content/10.1101/616128v1?rss=1 Ellison, C. K. Kan, J. Chlebek, J. L. Hummels, K. R. Panis, G. Viollier, P. H. Biais, N. Dalia, A. B. Brun, Y. 2019-04-24 doi:10.1101/616128 Cold Spring Harbor Laboratory Press 2019-04-24 <![CDATA[ Lowe Syndrome-linked endocytic adaptors direct membrane cycling kinetics with OCRL in Dictyostelium discoideum. ]]> https://biorxiv.org/content/10.1101/616664v1?rss=1 Luscher, A. Fröhlich, F. Barisch, C. Littlewood, C. Metcalfe, J. Leuba, F. Palma, A. Pirruccello, M. Cesareni, G. Stagi, M. Walther, T. C. Soldati, T. De Camilli, P. Swan, L. E. 2019-04-24 doi:10.1101/616664 Cold Spring Harbor Laboratory Press 2019-04-24 <![CDATA[ EEG resting-state large-scale brain network dynamics are related to depressive symptoms ]]> https://biorxiv.org/content/10.1101/619031v1?rss=1 Damborska, A. Tomescu, M. Honzirkova, E. Bartecek, R. Horinkova, J. Fedorova, S. Ondrus, S. Michel, C. 2019-04-26 doi:10.1101/619031 Cold Spring Harbor Laboratory Press 2019-04-26 <![CDATA[ Altered directed functional connectivity of the right amygdala in depression: high-density EEG study ]]> https://biorxiv.org/content/10.1101/620252v1?rss=1 Damborska, A. Rubega, M. Honzirkova, E. Bartecek, R. Horinkova, J. Fedorova, S. Ondrus, S. Michel, C. 2019-04-26 doi:10.1101/620252 Cold Spring Harbor Laboratory Press 2019-04-26 <![CDATA[ Sociobehavioural characteristics and HIV incidence in 29 sub-Saharan African countries: Unsupervised machine learning analysis using the Demographic and Health Surveys ]]> https://biorxiv.org/content/10.1101/620450v1?rss=1 Merzouki, A. Estill, J. Tal, K. Keiser, O. 2019-04-26 doi:10.1101/620450 Cold Spring Harbor Laboratory Press 2019-04-26 <![CDATA[ Functional genomics of the stable fly, Stomoxys calcitrans, reveals mechanisms underlying reproduction, host interactions, and novel targets for pest control ]]> https://biorxiv.org/content/10.1101/623009v1?rss=1 Olafson, P. U. Aksoy, S. Attardo, G. M. Buckmeier, G. Chen, X. Coates, C. J. Davis, M. Dykema, J. T. Emrich, S. J. Friedrich, M. Holmes, C. J. Ioannidis, P. Jansen, E. N. Jennings, E. C. Lawson, D. Martinson, E. O. Maslen, G. L. Meisel, R. P. Murphy, T. D. Nayduch, D. Nelson, D. R. Oyen, K. J. Raszick, T. J. Ribeiro, J. M. C. Robertson, H. M. Rosendale, A. J. Sackton, T. B. Swiger, S. L. Sze, S.-H. Tarone, A. M. Taylor, D. B. Warren, W. C. Waterhouse, R. M. Weirauch, M. T. Werren, J. H. Wilson, R. K. Zdobnov, E. M. Benoit, J. B. 2019-05-02 doi:10.1101/623009 Cold Spring Harbor Laboratory Press 2019-05-02 <![CDATA[ A genetically validated approach to detect inorganic polyphosphates in plants. ]]> https://biorxiv.org/content/10.1101/630129v1?rss=1 Zhu, J. Loubery, S. Broger, L. Lorenzo-Orts, L. Utz-Pugin, A. Chang, Y.-T. Hothorn, M. 2019-05-07 doi:10.1101/630129 Cold Spring Harbor Laboratory Press 2019-05-07 <![CDATA[ FACS-based isolation and RNA extraction of Secondary Cells from the Drosophila male Accessory Gland ]]> https://biorxiv.org/content/10.1101/630335v1?rss=1 IMMARIGEON, C. KARCH, F. MAEDA, R. K. 2019-05-13 doi:10.1101/630335 Cold Spring Harbor Laboratory Press 2019-05-13 <![CDATA[ Anterior Insula Reflects Inferential Errors in Value-Based Decision-making and Perception ]]> https://biorxiv.org/content/10.1101/644427v1?rss=1 Loued-Khenissi, L. Pfeuffer, A. Einhaeuser, W. Preuschoff, K. 2019-05-21 doi:10.1101/644427 Cold Spring Harbor Laboratory Press 2019-05-21 <![CDATA[ A role for Toxoplasma gondii chloroquine resistance transporter in bradyzoite viability and digestive vacuole maintenance ]]> https://biorxiv.org/content/10.1101/647669v1?rss=1 Kannan, G. Di Cristina, M. Schultz, A. J. Huynh, M.-H. Wang, F. Schultz, T. L. Lunghi, M. Coppens, I. Carruthers, V. B. 2019-05-24 doi:10.1101/647669 Cold Spring Harbor Laboratory Press 2019-05-24 <![CDATA[ Population history and genetic adaptation of the Fulani nomads: Inferences from genome-wide data and the lactase persistence trait ]]> https://biorxiv.org/content/10.1101/650986v1?rss=1 Vicente, M. Priehodova, E. Diallo, I. Podgorna, E. Poloni, E. S. Cerny, V. Schlebusch, C. M. 2019-05-27 doi:10.1101/650986 Cold Spring Harbor Laboratory Press 2019-05-27 <![CDATA[ A VERSATILE ROBOTIC PLATFORM FOR THE DESIGN OF NATURAL, THREE-DIMENSIONAL REACHING AND GRASPING TASKS IN MONKEYS ]]> https://biorxiv.org/content/10.1101/653840v1?rss=1 Barra, B. Badi, M. Perich, M. G. Conti, S. Salehian, S. S. M. Moreillon, F. Wurth, S. Kaeser, M. Passeraub, P. Milekovic, T. Billard, A. Micera, S. Capogrosso, M. 2019-06-02 doi:10.1101/653840 Cold Spring Harbor Laboratory Press 2019-06-02 <![CDATA[ Influence of genetic variants on gene expression in human pancreatic islets - implications for type 2 diabetes ]]> https://biorxiv.org/content/10.1101/655670v1?rss=1 Vinuela, A. Varshney, A. Bunt, M. v. d. Prasad, R. B. Asplund, O. B. Bennett, A. Boehnke, M. B. Brown, A. A. Erdos, M. R. Fadista, J. Hansson, O. Hatem, G. Howald, C. Iyengar, A. K. Johnson, P. Krus, U. MacDonald, P. E. Mahajan, A. E. Manning Fox, J. E. Narisu, N. Nylander, V. Orchard, P. E. Oskolkov, N. Panousis, N. I. Payne, A. Stitzel, M. L. Vadlamudi, S. Welch, R. Collins, F. S. Mohlke, K. L. Gloyn, A. L. Scott, L. L. Dermitzakis, E. L. Groop, L. L. Parker, S. C. McCarthy, M. L. 2019-05-31 doi:10.1101/655670 Cold Spring Harbor Laboratory Press 2019-05-31 <![CDATA[ Cytotoxicity of 1-deoxysphingolipid Unraveled by Genome-wide Genetic Screens and Lipidomics ]]> https://biorxiv.org/content/10.1101/658690v1?rss=1 Haribowo, A. G. Hannich, J. T. Michel, A. H. Megyeri, M. Schuldiner, M. Kornmann, B. Riezman, H. 2019-06-03 doi:10.1101/658690 Cold Spring Harbor Laboratory Press 2019-06-03 <![CDATA[ Three-dimensional analysis of β-cell proliferation by a novel mouse model ]]> https://biorxiv.org/content/10.1101/659904v1?rss=1 Tokumoto, S. Yabe, D. Tatsuoka, H. Usui, R. Fauzi, M. Botagarova, A. Goto, H. Herrera, P. L. Ogura, M. Inagaki, N. 2019-06-04 doi:10.1101/659904 Cold Spring Harbor Laboratory Press 2019-06-04 <![CDATA[ Mps1 releases Mad1 from nuclear pores to ensure a robust mitotic checkpoint and accurate chromosome segregation ]]> https://biorxiv.org/content/10.1101/659938v1?rss=1 Osswald, M. Cunha-Silva, S. Goemann, J. Barbosa, J. Santos, L. M. Resende, P. Bange, T. Sunkel, C. Conde, C. 2019-06-04 doi:10.1101/659938 Cold Spring Harbor Laboratory Press 2019-06-04 <![CDATA[ Molecularly distinct cores coexist inside stress granules ]]> https://biorxiv.org/content/10.1101/663955v1?rss=1 Cirillo, L. Cieren, A. Gotta, M. 2019-06-07 doi:10.1101/663955 Cold Spring Harbor Laboratory Press 2019-06-07 <![CDATA[ Deviant EEG resting-state large-scale brain network dynamics in euthymic bipolar disorder patients ]]> https://biorxiv.org/content/10.1101/668004v1?rss=1 Damborska, A. Piguet, C. Aubry, J.-M. Dayer, A. Michel, C. Berchio, C. 2019-06-12 doi:10.1101/668004 Cold Spring Harbor Laboratory Press 2019-06-12 <![CDATA[ The mitochondrial HSP90 paralog TRAP1 forms an OXPHOS-regulated tetramer and is involved in maintaining mitochondrial metabolic homeostasis ]]> https://biorxiv.org/content/10.1101/679431v1?rss=1 Joshi, A. Dai, J. Lee, J. Mohammadi Ghahhari, N. Segala, G. Beebe, K. Tsai, F. T. F. Neckers, L. Picard, D. 2019-06-21 doi:10.1101/679431 Cold Spring Harbor Laboratory Press 2019-06-21 <![CDATA[ Brain functional connectivity dynamics in the aftermaths of affective and cognitive events. ]]> https://biorxiv.org/content/10.1101/685396v1?rss=1 Gaviria, J. Rey, G. Bolton, T. Delgado, J. Van De Ville, D. Vuilleumier, P. 2019-06-27 doi:10.1101/685396 Cold Spring Harbor Laboratory Press 2019-06-27 <![CDATA[ Linking alpha oscillations, attention and inhibitory control in adult ADHD with EEG neurofeedback ]]> https://biorxiv.org/content/10.1101/689398v1?rss=1 Deiber, M.-P. Hasler, R. Colin, J. Dayer, A. Aubry, J.-M. Baggio, S. Perroud, N. Ros, T. 2019-07-02 doi:10.1101/689398 Cold Spring Harbor Laboratory Press 2019-07-02 <![CDATA[ Mechanistic insights into bacterial metabolic reprogramming from omics-integrated genome-scale models ]]> https://biorxiv.org/content/10.1101/690164v1?rss=1 Hadadi, N. Pandey, V. Chiappino-Pepe, A. Morales, M. Gallart-Ayala, H. Mehl, F. Ivanisevic, J. Sentchilo, V. Meer, J. v. d. 2019-07-03 doi:10.1101/690164 Cold Spring Harbor Laboratory Press 2019-07-03 <![CDATA[ Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2. ]]> https://biorxiv.org/content/10.1101/692228v1?rss=1 Okuda, S. Fujita, S. Moretti, A. Hohmann, U. Gonzalez Doblas, V. G. Ma, Y. Pfister, A. Brandt, B. Geldner, N. Hothorn, M. 2019-07-04 doi:10.1101/692228 Cold Spring Harbor Laboratory Press 2019-07-04 <![CDATA[ Nitric Oxide Mediates Neuro-Glial Interaction that Shapes Drosophila Circadian Behavior ]]> https://biorxiv.org/content/10.1101/700971v1?rss=1 Nagoshi, E. Kozlov, A. 2019-07-12 doi:10.1101/700971 Cold Spring Harbor Laboratory Press 2019-07-12 <![CDATA[ Taxonomically informed scoring enhances confidence in natural products annotation ]]> https://biorxiv.org/content/10.1101/702308v1?rss=1 Rutz, A. Donoue-Kubo, M. ollivier, s. BISSON, J. Bagheri, M. Saesong, T. Ebrahimi, S. N. Ingkaninan, K. Wolfender, J.-L. Allard, P.-M. 2019-07-14 doi:10.1101/702308 Cold Spring Harbor Laboratory Press 2019-07-14 <![CDATA[ Structural control energy of resting-state functional brain states reveals inefficient brain dynamics in psychosis vulnerability. ]]> https://biorxiv.org/content/10.1101/703561v1?rss=1 Zoeller, D. Sandini, C. Schaer, M. Eliez, S. Bassett, D. Van De Ville, D. 2019-07-16 doi:10.1101/703561 Cold Spring Harbor Laboratory Press 2019-07-16 <![CDATA[ Convergent changes in gene expression associated with repeated transitions between hummingbird and bee pollinated flowers ]]> https://biorxiv.org/content/10.1101/706127v1?rss=1 Serrano-Serrano, M. L. Marcionetti, A. Perret, M. Salamin, N. 2019-07-17 doi:10.1101/706127 Cold Spring Harbor Laboratory Press 2019-07-17 <![CDATA[ Neural correlates of the DMT experience as assessed via multivariate EEG ]]> https://biorxiv.org/content/10.1101/706283v1?rss=1 Timmermann, C. Roseman, L. Schartner, M. Milliere, R. Williams, L. Erritzoe, D. Muthukumaraswamy, S. Ashton, M. Bendrioua, A. Kaur, O. Turton, S. Nour, M. Day, C. Leech, R. Nutt, D. Carhart-Harris, R. 2019-07-18 doi:10.1101/706283 Cold Spring Harbor Laboratory Press 2019-07-18 <![CDATA[ Anisotropic ESCRT-III architecture governs helical membrane tube formation ]]> https://biorxiv.org/content/10.1101/716308v1?rss=1 Moser von Filseck, J. Barberi, L. Talledge, N. Johnson, I. Frost, A. Lenz, M. Roux, A. 2019-07-26 doi:10.1101/716308 Cold Spring Harbor Laboratory Press 2019-07-26 <![CDATA[ Leveraging biobank-scale rare and common variant analyses to identify ASPHD1 as the main driver of reproductive traits in the 16p11.2 locus ]]> https://biorxiv.org/content/10.1101/716415v1?rss=1 Männik, K. Arbogast, T. Lepamets, M. Lepik, K. Pellaz, A. Ademi, H. Kupchinsky, Z. A. Ellegood, J. Attanasio, C. Messina, A. Rotman, S. Martin-Brevet, S. Dubruc, E. Chrast, J. Lerch, J. P. Qiu, L. R. Laisk, T. The 16p11.2 European Consortium, The Simons VIP Consortium, The eQTLGen Consortium, Henkelman, M. R. Jacquemont, S. Herault, Y. Lindgren, C. M. Peterson, H. Stehle, J. C. Katsanis, N. Kutalik, Z. Nef, S. Draganski, B. Davis, E. E. Mägi, R. Reymond, A. 2019-07-26 doi:10.1101/716415 Cold Spring Harbor Laboratory Press 2019-07-26 <![CDATA[ Vps4 triggers sequential subunit exchange in ESCRT-III polymers that drives membrane constriction and fission ]]> https://biorxiv.org/content/10.1101/718080v1?rss=1 Pfitzner, A.-K. Mercier, V. Roux, A. 2019-07-29 doi:10.1101/718080 Cold Spring Harbor Laboratory Press 2019-07-29 <![CDATA[ Salivary gland macrophages assist tissue-resident CD8+ T cell immune surveillance ]]> https://biorxiv.org/content/10.1101/723791v1?rss=1 Stolp, B. Thelen, F. Ficht, X. Altenburger, L. Ruef, N. Inavalli, K. Germann, P. Page, N. Moalli, F. Raimondi, A. Keyser, K. Safari, S. Barone, F. Dettmer, M. Merkler, D. Iannacone, M. Sharpe, J. Schlapbach, C. Fackler, O. Naegerl, V. Stein, J. 2019-08-05 doi:10.1101/723791 Cold Spring Harbor Laboratory Press 2019-08-05 <![CDATA[ Myelin and nodal plasticity modulate action potential conduction in the adult mouse brain ]]> https://biorxiv.org/content/10.1101/726760v1?rss=1 Cullen, C. L. Pepper, R. E. Clutterbuck, M. T. Pitman, K. A. Oorschot, V. Auderset, L. Tang, A. D. Ramm, G. Emery, B. Rodger, J. Jolivet, R. B. Young, K. M. 2019-08-06 doi:10.1101/726760 Cold Spring Harbor Laboratory Press 2019-08-06 <![CDATA[ Motor improvement estimation and task adaptation for personalized robot-aided therapy: a feasibility study ]]> https://biorxiv.org/content/10.1101/728725v1?rss=1 Giang, C. Pirondini, E. Kinany, N. Pierella, C. Panarese, A. Coscia, M. Miehlbradt, J. Magnin, C. Nicolo, P. Guggisberg, A. Micera, S. 2019-08-16 doi:10.1101/728725 Cold Spring Harbor Laboratory Press 2019-08-16 <![CDATA[ Converging intracortical signatures of two separated processing timescales in human early auditory cortex. ]]> https://biorxiv.org/content/10.1101/730002v1?rss=1 Baroni, F. Morillon, B. Trebuchon, A. Liegeois-Chauvel, C. Olasagasti, I. Giraud, A.-L. 2019-08-08 doi:10.1101/730002 Cold Spring Harbor Laboratory Press 2019-08-08 <![CDATA[ Conidial melanin of the human pathogenic fungus Aspergillus fumigatus disrupts cell autonomous defenses in amoebae ]]> https://biorxiv.org/content/10.1101/730879v1?rss=1 Ferling, I. Dunn, J. D. Ferling, A. Soldati, T. Hillmann, F. 2019-08-09 doi:10.1101/730879 Cold Spring Harbor Laboratory Press 2019-08-09 <![CDATA[ Intersecting vulnerabilities: Climatic and demographic contributions to future population exposure to Aedes-borne viruses in the United States ]]> https://biorxiv.org/content/10.1101/732644v1?rss=1 30% under the strongest climate change mitigation scenario. The results emphasize the crucial role that socioeconomic and demographic change play in shaping future population vulnerability and exposure to Aedes-borne virus transmission risk in the United States, and underscore the importance of including socioeconomic scenarios in projections of climate-related vector-borne disease impacts. ]]> Rohat, G. Monaghan, A. Hayden, M. H. Ryan, S. J. Wilhelmi, O. V. 2019-08-12 doi:10.1101/732644 Cold Spring Harbor Laboratory Press 2019-08-12 <![CDATA[ MCF2 is linked to a complex perisylvian syndrome and affects cortical lamination ]]> https://biorxiv.org/content/10.1101/733444v1?rss=1 Molinard-Chenu, A. Fluss, J. Guipponi, M. Laurent, S. Dayer, A. 2019-08-13 doi:10.1101/733444 Cold Spring Harbor Laboratory Press 2019-08-13 <![CDATA[ Superior Colliculus to VTA pathway controls orienting behavior during conspecific interaction. ]]> https://biorxiv.org/content/10.1101/735340v1?rss=1 Bellone, C. Prevost-Solie, C. Contestaile, A. Musardo, S. Huber, C. Bariselli, S. Carleton, A. 2019-08-14 doi:10.1101/735340 Cold Spring Harbor Laboratory Press 2019-08-14 <![CDATA[ Carbonic anhydrase VII regulates dendritic spine morphology and density via actin filament bundling ]]> https://biorxiv.org/content/10.1101/736868v1?rss=1 Bertling, E. Blaesse, P. Seja, P. Kremneva, E. Gateva, G. Virtanen, M. A. Summanen, M. Spoljaric, I. Blaesse, M. Paavilainen, V. Vutskits, L. Kaila, K. Hotulainen, P. Ruusuvuori, E. 2019-08-19 doi:10.1101/736868 Cold Spring Harbor Laboratory Press 2019-08-19 <![CDATA[ ATLAS: a Snakemake workflow for assembly, annotation, and genomic binning of metagenome sequence data ]]> https://biorxiv.org/content/10.1101/737528v1?rss=1 Kieser, S. Brown, J. Zdobnov, E. M. Trajkovski, M. McCue, L. A. 2019-08-20 doi:10.1101/737528 Cold Spring Harbor Laboratory Press 2019-08-20 <![CDATA[ Fork Pausing Complex Engages Topoisomerases at the Replisome ]]> https://biorxiv.org/content/10.1101/738328v1?rss=1 Shyian, M. Albert, B. Zupan, A. M. Ivanitsa, V. Charbonnet, G. Dilg, D. Shore, D. 2019-08-19 doi:10.1101/738328 Cold Spring Harbor Laboratory Press 2019-08-19 <![CDATA[ Bacterial cell cycle and growth phase switch by the essential transcriptional regulator CtrA ]]> https://biorxiv.org/content/10.1101/739516v1?rss=1 Delaby, M. Panis, G. Viollier, P. H. 2019-08-20 doi:10.1101/739516 Cold Spring Harbor Laboratory Press 2019-08-20 <![CDATA[ Bypass of an epigenetic S-phase transcriptional module by convergent nutrient stress signals ]]> https://biorxiv.org/content/10.1101/741363v1?rss=1 DELABY, M. PANIS, G. FUMEAUX, C. DEGEORGES, L. VIOLLIER, P. H. 2019-08-21 doi:10.1101/741363 Cold Spring Harbor Laboratory Press 2019-08-21 <![CDATA[ Shared Genetic Risk between Eating Disorder- and Substance-Use-Related Phenotypes: Evidence from Genome-Wide Association Studies ]]> https://biorxiv.org/content/10.1101/741512v1?rss=1 Munn-Chernoff, M. Johnson, E. C. Chou, Y.-L. Coleman, J. R. Thornton, L. M. Walters, R. K. Yilmaz, Z. Baker, J. Hubel, C. Gordon, S. Medland, S. Watson, H. Gaspar, H. A. Bryois, J. Hinney, A. Leppa, V. Mattheisen, M. Ripke, S. Yao, S. Giusti-Rodriguez, P. Hanscombe, K. B. Adan, R. Alredsson, L. Ando, T. Andreassen, O. A. Berrettini, W. Boehm, I. Boni, C. Boraska Perica, V. Buehren, K. Burghardt, R. Cassina, M. Cichon, S. Clementi, M. Cone, R. Courtet, P. Crow, S. Crowley, J. J. Danner, U. Davis, O. de Zwaan, M. Dedoussis, G. Degortes, D. DeSocio, J. 2019-08-23 doi:10.1101/741512 Cold Spring Harbor Laboratory Press 2019-08-23 <![CDATA[ Traction forces control cell-edge dynamics and mediate distance-sensitivity during cell polarization ]]> https://biorxiv.org/content/10.1101/745687v1?rss=1 Messi, Z. Bornert, A. Raynaud, F. Verkhovsky, A. 2019-08-23 doi:10.1101/745687 Cold Spring Harbor Laboratory Press 2019-08-23 <![CDATA[ Mitochondrial RNA granules are fluid condensates, positioned by membrane dynamics ]]> https://biorxiv.org/content/10.1101/747055v1?rss=1 Rey, T. Zaganelli, S. Cuillery, E. Martinou, J.-C. Manley, S. 2019-08-27 doi:10.1101/747055 Cold Spring Harbor Laboratory Press 2019-08-27 <![CDATA[ Single-cell transcriptomics reveals temporal dynamics of critical regulators of germ cell fate during mouse sex determination ]]> https://biorxiv.org/content/10.1101/747279v1?rss=1 Mayere, C. Neirijnck, Y. Sararols, P. Stevant, I. Kühne, F. Chassot, A.-A. Chaboissier, M.-C. Dermitzakis, E. Nef, S. 2019-08-29 doi:10.1101/747279 Cold Spring Harbor Laboratory Press 2019-08-29 <![CDATA[ A key role for phosphorylation of PsbH in the biogenesis and repair of photosystem II in Chlamydomonas ]]> https://biorxiv.org/content/10.1101/754721v1?rss=1 Riche, A. Lefebvre-Legendre, L. Goldschmidt-Clermont, M. 2019-09-03 doi:10.1101/754721 Cold Spring Harbor Laboratory Press 2019-09-03 <![CDATA[ Three-dimensional chromatin interactions remain stable upon CAG/CTG repeat expansion ]]> https://biorxiv.org/content/10.1101/754838v1?rss=1 Ruiz Buendia, G. A. Leleu, M. Marzetta, F. Vanzan, L. Tan, J. Y. Murr, R. Marques, A. C. Baubec, T. Xenarios, I. Dion, V. 2019-09-02 doi:10.1101/754838 Cold Spring Harbor Laboratory Press 2019-09-02 <![CDATA[ Chemical genetics of AGC-kinases reveals shared targets of Ypk1, Protein Kinase A and Sch9 ]]> https://biorxiv.org/content/10.1101/756841v1?rss=1 Plank, M. Perepelkina, M. Müller, M. Vaga, S. Zou, X. Berti, M. Saarbach, J. Haesendonckx, S. Winssinger, N. Aebersold, R. Loewith, R. 2019-09-04 doi:10.1101/756841 Cold Spring Harbor Laboratory Press 2019-09-04 <![CDATA[ Localized calcium accumulations prime synapses for phagocyte removal in cortical neuroinflammation ]]> https://biorxiv.org/content/10.1101/758193v1?rss=1 Jafari, M. Schumacher, A.-M. Snaidero, N. Neziraj, T. Ullrich Gavilanes, E. M. Jürgens, T. Florez Weidinger, J. D. Schmidt, S. S. Beltran, E. Hagan, N. Woodworth, L. Ofengeim, D. Gans, J. Wolf, F. Kreutzfeldt, M. Portugues, R. Merkler, D. Misgeld, T. Kerschensteiner, M. 2019-09-04 doi:10.1101/758193 Cold Spring Harbor Laboratory Press 2019-09-04 <![CDATA[ Co-ordinated Ras and Rac activity shapes macropinocytic cups and enables phagocytosis of geometrically diverse bacteria ]]> https://biorxiv.org/content/10.1101/763748v1?rss=1 Buckley, C. M. Pots, H. Gueho, A. Phillips, B. A. Gilsbach, B. Nikolaev, A. Soldati, T. Parnell, A. J. Kortholt, A. King, J. S. 2019-09-10 doi:10.1101/763748 Cold Spring Harbor Laboratory Press 2019-09-10 <![CDATA[ Ndc80/Nuf2-like protein KKIP1 connects a stable kinetoplastid outer kinetochore complex to the inner kinetochore and responds to metaphase tension ]]> https://biorxiv.org/content/10.1101/764829v1?rss=1 Brusini, L. D'Archivio, S. McDonald, J. Wickstead, B. 2019-09-10 doi:10.1101/764829 Cold Spring Harbor Laboratory Press 2019-09-10 <![CDATA[ Molecular architecture of the DNA-binding sites of the P-loop ATPases MipZ and ParA from Caulobacter crescentus ]]> https://biorxiv.org/content/10.1101/766287v1?rss=1 Refes, Y. He, B. Corrales-Guerrero, L. Steinchen, W. Panis, G. Viollier, P. H. Bange, G. Thanbichler, M. 2019-09-12 doi:10.1101/766287 Cold Spring Harbor Laboratory Press 2019-09-12 <![CDATA[ Nanoscale topography templates the organization of stable clathrin/AP-2 structures ]]> https://biorxiv.org/content/10.1101/767590v1?rss=1 Picas, L. Carretero-Genevrier, A. Sansen, T. Rathar, R. Sanchez-Fuentes, D. Colom-Diego, A. El Alaoui, F. Viaud, J. Gaudin, R. Matile, S. de Rossi, S. Macchione, M. 2019-09-12 doi:10.1101/767590 Cold Spring Harbor Laboratory Press 2019-09-12 <![CDATA[ Molecular pathway of influenza pan-neuraminidase inhibitors resistance in an immunocompromised patient ]]> https://biorxiv.org/content/10.1101/768614v1?rss=1 Abed, Y. Schibler, M. Checkmahomed, L. Carbonneau, J. Venable, M.-C. Giannotti, F. Goncalves, A. R. Kaiser, L. Boivin, G. 2019-09-16 doi:10.1101/768614 Cold Spring Harbor Laboratory Press 2019-09-16 <![CDATA[ Audio-visual combination of syllables involves time-sensitive dynamics following from fusion failure ]]> https://biorxiv.org/content/10.1101/771634v1?rss=1 Bouton, S. Delgado Saa, J. F. Olasagasti, I. Giraud, A.-L. 2019-09-18 doi:10.1101/771634 Cold Spring Harbor Laboratory Press 2019-09-18 <![CDATA[ Genome-wide association study of Alzheimer’s disease CSF biomarkers in the EMIF-AD Multimodal Biomarker Discovery dataset ]]> https://biorxiv.org/content/10.1101/774554v1?rss=1 Hong, S. Prokopenko, D. Dobricic, V. Kilpert, F. Bos, I. Vos, S. J. B. Tijms, B. M. Andreasson, U. Blennow, K. Vandenberghe, R. Cleynen, I. Gabel, S. Schaeverbeke, J. Scheltens, P. Teunissen, C. E. Niemantsverdriet, E. Engelborghs, S. Frisoni, G. Blin, O. Richardson, J. C. Bordet, R. Molinuevo, J. L. Rami, L. Alzheimer's Disease Neuroimaging Initiative (ADNI), Kettunen, P. Wallin, A. Lleo, A. Sala, I. Popp, J. Peyratout, G. Martinez-Lage, P. Tainta, M. Dobson, R. J. B. Legido-Quigley, C. Sleegers, K. Broeckhoven, C. V. Kate, M. t. Barkhof, F. Zetterberg 2019-09-23 doi:10.1101/774554 Cold Spring Harbor Laboratory Press 2019-09-23 <![CDATA[ Dynamic encoding of perceptual features in primary somatosensory cortex upon reversal learning ]]> https://biorxiv.org/content/10.1101/782847v1?rss=1 Chereau, R. Bawa, T. Fodoulian, L. Carleton, A. Pages, S. Holtmaat, A. 2019-09-26 doi:10.1101/782847 Cold Spring Harbor Laboratory Press 2019-09-26 <![CDATA[ The GTEx Consortium atlas of genetic regulatory effects across human tissues ]]> https://biorxiv.org/content/10.1101/787903v1?rss=1 Aguet, F. Barbeira, A. N. Bonazzola, R. Brown, A. Castel, S. E. Jo, B. Kasela, S. Kim-Hellmuth, S. Liang, Y. Oliva, M. Parsana, P. E. Flynn, E. Fresard, L. Gaamzon, E. R. Hamel, A. R. He, Y. Hormozdiari, F. Mohammadi, P. Munoz-Aguirre, M. Park, Y. Saha, A. Segrc, A. V. Strober, B. J. Wen, X. Wucher, V. Das, S. Garrido-Martin, D. Gay, N. R. Handsaker, R. E. Hoffman, P. J. Kashin, S. Kwong, A. Li, X. MacArthur, D. Rouhana, J. M. Stephens, M. Todres, E. Vinuela, A. Wang, G. Zou, Y. The GTEx Consortium, Brown, C. D. Cox, N. Dermitzakis, E. Engelhardt, 2019-10-03 doi:10.1101/787903 Cold Spring Harbor Laboratory Press 2019-10-03 <![CDATA[ Cortico-striatal synaptic plasticity underlying compulsive reward seeking ]]> https://biorxiv.org/content/10.1101/789495v1?rss=1 Harada, M. Hiver, A. Pascoli, V. Lüscher, C. 2019-10-01 doi:10.1101/789495 Cold Spring Harbor Laboratory Press 2019-10-01 <![CDATA[ Bacterial cell cycle control by citrate synthase independent of enzymatic activity ]]> https://biorxiv.org/content/10.1101/799742v1?rss=1 Berge, M. Pezzatti, J. Gonzalez-Ruiz, V. Theraulaz, L. Rudaz, S. Viollier, P. H. 2019-10-10 doi:10.1101/799742 Cold Spring Harbor Laboratory Press 2019-10-10 <![CDATA[ Multi-timescale hybrid components of the functional brain connectome: A bimodal EEG-fMRI decomposition ]]> https://biorxiv.org/content/10.1101/800797v1?rss=1 Wirsich, J. Amico, E. Guye, M. Ranjeva, J.-P. Giraud, A.-L. Goni, J. Sadaghiani, S. 2019-10-10 doi:10.1101/800797 Cold Spring Harbor Laboratory Press 2019-10-10 <![CDATA[ Neuro-Computational Foundations of Moral Preferences ]]> https://biorxiv.org/content/10.1101/801936v1?rss=1 Ugazio, G. Grueschow, M. Polania, R. Lamm, C. Tobler, P. Ruff, C. 2019-10-13 doi:10.1101/801936 Cold Spring Harbor Laboratory Press 2019-10-13 <![CDATA[ Impaired renal gluconeogenesis is a major determinant of acute kidney injury associated mortality ]]> https://biorxiv.org/content/10.1101/804997v1?rss=1 Legouis, D. Ricksten, S.-E. Faivre, A. Gariani, K. Galichon, P. Berchtold, L. Feraille, E. Koppitch, K. Hertig, A. Martin, P.-Y. Naesens, M. Pugin, J. McMahon, A. P. Cippà, P. E. de Seigneux, S. 2019-10-16 doi:10.1101/804997 Cold Spring Harbor Laboratory Press 2019-10-16 <![CDATA[ Cell type specific genetic regulation of gene expression across human tissues ]]> https://biorxiv.org/content/10.1101/806117v1?rss=1 Kim-Hellmuth, S. Aguet, F. Oliva, M. Munoz-Aguirre, M. Wucher, V. Kasela, S. Castel, S. E. Hamel, A. Vinuela, A. Roberts, A. L. Mangul, S. Wen, X. Wang, G. Barbeira, A. Garrido-Martin, D. Nadel, B. Zou, Y. Bonazzola, R. Quan, J. Brown, A. Martinez-Perez, A. Soria, J. M. Getz, G. Dermitzakis, E. Small, K. S. Stephens, M. Xi, H. S. Im, H. K. Guigo, R. Segre, A. Stranger, B. Ardlie, K. Lappalainen, T. 2019-10-16 doi:10.1101/806117 Cold Spring Harbor Laboratory Press 2019-10-16 <![CDATA[ A two-way molecular dialogue between embryo and endosperm required for seed development ]]> https://biorxiv.org/content/10.1101/809368v1?rss=1 Doll, N. M. Royek, S. Fujita, S. Okuda, S. Stintzi, A. Widiez, T. Hothorn, M. Schaller, A. Geldner, N. Ingram, G. 2019-10-17 doi:10.1101/809368 Cold Spring Harbor Laboratory Press 2019-10-17 <![CDATA[ A Complex Regulatory Landscape Involved In The Development Of External Genitals ]]> https://biorxiv.org/content/10.1101/810788v1?rss=1 Amandio, A. R. Lopez-Delisle, L. Bolt, C. C. Mascrez, B. Duboule, D. 2019-10-21 doi:10.1101/810788 Cold Spring Harbor Laboratory Press 2019-10-21 <![CDATA[ Feature-based Molecular Networking in the GNPS Analysis Environment ]]> https://biorxiv.org/content/10.1101/812404v1?rss=1 Nothias, L. F. Petras, D. Schmid, R. Duehrkop, K. Rainer, J. Sarvepalli, A. Protsyuk, I. Ernst, M. Tsugawa, H. Fleischauer, M. Aicheler, F. Aksenov, A. Alka, O. Allard, P.-M. Barsch, A. Cachet, X. Caraballo, M. Da Silva, R. Dang, T. Garg, N. Gauglitz, J. M. Gurevich, A. Isaac, G. Jarmusch, A. K. Kamenik, Z. Kang, K. B. Kessler, N. Koester, I. Korf, A. Le Gouellec, A. Ludwig, M. Martin H., C. McCall, L.-I. McSayles, J. Meyer, S. Mohimani, H. Morsy, M. Moyne, O. Neumann, S. Neuweger, H. Nguyen, N. H. Esposito-Nothias, M. Paolini, J. Phelan, V. Pluskal, 2019-10-20 doi:10.1101/812404 Cold Spring Harbor Laboratory Press 2019-10-20 <![CDATA[ Patched regulates lipid homeostasis by controlling cellular cholesterol levels ]]> https://biorxiv.org/content/10.1101/816256v1?rss=1 Cadena Del Castillo, C. E. Hannich, J. T. Kaech, A. Chiyoda, H. Fukuyama, M. Færgeman, N. J. Riezman, H. Spang, A. 2019-10-23 doi:10.1101/816256 Cold Spring Harbor Laboratory Press 2019-10-23 <![CDATA[ Brain networks processing temporal information in dynamic facial expressions ]]> https://biorxiv.org/content/10.1101/819276v1?rss=1 Skiba, R. M. Vuilleumier, P. 2019-10-28 doi:10.1101/819276 Cold Spring Harbor Laboratory Press 2019-10-28 <![CDATA[ Rationally designed oral vaccines can set an evolutionary trap for Salmonella Typhimurium ]]> https://biorxiv.org/content/10.1101/824821v1?rss=1 Diard, M. Bakkeren, E. Hoces, D. Lentsch, V. Arnoldini, M. Boehi, F. Schumann-Moor, K. Adamcik, J. Piccoli, L. Lanzavecchia, A. Stadtmueller, B. Donohue, N. Vanderwoude, M. Viollier, P. Falquet, L. Hockenberry, A. Wuethrich, D. Bonfiglio, F. Egli, A. Zandomeneghi, G. Mezzenga, R. Holst, O. Meier, B. Hardt, W.-D. Slack, E. 2019-10-31 doi:10.1101/824821 Cold Spring Harbor Laboratory Press 2019-10-31 <![CDATA[ Dissociable brain mechanisms for long-term memory of disgust- and fear- related associations ]]> https://biorxiv.org/content/10.1101/825844v1?rss=1 Riegel, M. Wierzba, M. Wypych, M. Ritchey, M. Jednorog, K. Grabowska, A. Vuilleumier, P. Marchewka, A. 2019-10-31 doi:10.1101/825844 Cold Spring Harbor Laboratory Press 2019-10-31 <![CDATA[ Benefits of motor imagery practice during arm-immobilization on the sensorimotor cortical networks and sleep features ]]> https://biorxiv.org/content/10.1101/828889v1?rss=1 Debarnot, U. Perrault, A. A. Sterpenich, V. A. Legendre, G. Huber, C. Guillot, A. Schwartz, S. 2019-11-02 doi:10.1101/828889 Cold Spring Harbor Laboratory Press 2019-11-02 <![CDATA[ Formal string instrument training in a class setting enhances cognitive and sensorimotor development of primary school children ]]> https://biorxiv.org/content/10.1101/829077v1?rss=1 James, C. E. Zuber, S. Dupuis-Lozeron, E. Abdili, L. Gervaise, D. Kliegel, M. 2019-11-04 doi:10.1101/829077 Cold Spring Harbor Laboratory Press 2019-11-04 <![CDATA[ Using structural connectivity to augment community structure in EEG functional connectivity ]]> https://biorxiv.org/content/10.1101/831743v1?rss=1 Glomb, K. Mullier, E. Carboni, M. Rubega, M. Iannotti, G. Tourbier, S. Seeber, M. Vulliemoz, S. Hagmann, P. 2019-11-05 doi:10.1101/831743 Cold Spring Harbor Laboratory Press 2019-11-05 <![CDATA[ A generalizable multivariate brain pattern for interpersonal guilt ]]> https://biorxiv.org/content/10.1101/835520v1?rss=1 Yu, H. Koban, L. Chang, L. J. Wagner, U. Krishnan, A. Vuilleumier, P. Zhou, X. Wager, T. 2019-11-09 doi:10.1101/835520 Cold Spring Harbor Laboratory Press 2019-11-09 <![CDATA[ The macrophage-expressed gene (mpeg) 1 identifies a subpopulation of B cells in the adult zebrafish ]]> https://biorxiv.org/content/10.1101/836098v1?rss=1 View larger version (30K): org.highwire.dtl.DTLVardef@128a738org.highwire.dtl.DTLVardef@1fa6097org.highwire.dtl.DTLVardef@db61b2org.highwire.dtl.DTLVardef@eb2e2e_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Ferrero, G. Gomez, E. Iyer, S. Rovira, M. Miserocchi, M. Langenau, D. M. Bertrand, J. Y. Wittamer, V. 2019-11-10 doi:10.1101/836098 Cold Spring Harbor Laboratory Press 2019-11-10 <![CDATA[ Strong information-limiting correlations in early visual areas ]]> https://biorxiv.org/content/10.1101/842724v1?rss=1 Montijn, J. S. Liu, R. G. Aschner, A. Kohn, A. Latham, P. E. Pouget, A. 2019-11-15 doi:10.1101/842724 Cold Spring Harbor Laboratory Press 2019-11-15 <![CDATA[ Machine learning predicts immunoglobulin light chain toxicity through somatic mutations ]]> https://biorxiv.org/content/10.1101/849901v1?rss=1 Garofalo, M. Piccoli, L. Ravasio, S. Foglierini, M. Matkovic, M. Sgrignani, J. Prunotto, M. Michielin, O. Lanzavecchia, A. Cavalli, A. 2019-11-21 doi:10.1101/849901 Cold Spring Harbor Laboratory Press 2019-11-21 <![CDATA[ Switch from translation initiation to elongation needs Not4 and Not5 collaboration ]]> https://biorxiv.org/content/10.1101/850859v1?rss=1 Allen, G. E. Panasenko, O. O. Villanyi, Z. Zagatti, M. Weiss, B. Polte, C. Ignatova, Z. Collart, M. 2019-11-22 doi:10.1101/850859 Cold Spring Harbor Laboratory Press 2019-11-22 <![CDATA[ Loss of histone H3.3 results in DNA replication defects and altered origin dynamics in C. elegans ]]> https://biorxiv.org/content/10.1101/854455v1?rss=1 Strobino, M. Wenda, J. M. Steiner, F. A. 2019-11-25 doi:10.1101/854455 Cold Spring Harbor Laboratory Press 2019-11-25 <![CDATA[ Phase separation of Ede1 promotes the initiation of endocytic events ]]> https://biorxiv.org/content/10.1101/861203v1?rss=1 Kozak, M. Kaksonen, M. 2019-12-02 doi:10.1101/861203 Cold Spring Harbor Laboratory Press 2019-12-02 <![CDATA[ Acetobacteraceae in the honey bee gut comprise two distant clades with diverging metabolism and ecological niches ]]> https://biorxiv.org/content/10.1101/861260v1?rss=1 Bonilla-Rosso, G. Paredes, J. C. Das, S. Ellegaard, K. M. Emery, O. Garcia-Garcera, M. Glover, N. Hadadi, N. van der Meer, J. R. SAGE class 2017-18, Tagini, F. Engel, P. 2019-12-06 doi:10.1101/861260 Cold Spring Harbor Laboratory Press 2019-12-06 <![CDATA[ Genomics of Human Respiratory Syncytial Virus Vaccine Attenuation ]]> https://biorxiv.org/content/10.1101/862185v1?rss=1 Junier, T. Kaiser, L. Chaturvedi, N. Fellay, J. 2019-12-02 doi:10.1101/862185 Cold Spring Harbor Laboratory Press 2019-12-02 <![CDATA[ Glial cell mechanosensitivity is reversed by adhesion cues ]]> https://biorxiv.org/content/10.1101/865303v1?rss=1 Tomba, C. Migdal, C. Fuard, D. Villard, C. Nicolas, A. 2019-12-05 doi:10.1101/865303 Cold Spring Harbor Laboratory Press 2019-12-05 <![CDATA[ Agonist-selective recruitment of engineered protein probes and of GRK2 by opioid receptors in living cells ]]> https://biorxiv.org/content/10.1101/866780v1?rss=1 Stoeber, M. Jullie, D. Li, J. Chakraborty, S. Majumdar, S. Lambert, N. A. Manglik, A. von Zastrow, M. 2019-12-05 doi:10.1101/866780 Cold Spring Harbor Laboratory Press 2019-12-05 <![CDATA[ Oxidation-sensitive cysteines drive IL-38 amyloid formation ]]> https://biorxiv.org/content/10.1101/2023.03.26.534252v1?rss=1 Diaz-Barreiro, A. Cereghetti, G. Tonacini, J. Talabot-Ayer, D. Kieffer-Jaquinod, S. Huard, A. Swale, C. Coute, Y. Peter, M. Frances-Monerris, A. Palmer, G. 2023-03-26 doi:10.1101/2023.03.26.534252 Cold Spring Harbor Laboratory Press 2023-03-26 <![CDATA[ RFIDeep: Unfolding the Potential of Deep Learning forRadio-Frequency Identification ]]> https://biorxiv.org/content/10.1101/2023.03.25.534127v1?rss=1 Bardon, G. Cristofari, R. Winterl, A. Barracho, T. Benoiste, M. Ceresa, C. Chatelain, N. Courtecuisse, J. Fernandes, F. A. N. Gauthier-Clerc, M. Gendner, J.-P. Handrich, Y. Houstin, A. Krellenstein, A. Lecomte, N. Salmon, C.-E. Trucchi, E. Vallas, B. Wong, E. M. Zitterbart, D. P. Le Bohec, C. 2023-03-27 doi:10.1101/2023.03.25.534127 Cold Spring Harbor Laboratory Press 2023-03-27 <![CDATA[ Ric8 proteins as the neomorphic partners of G alpha o in GNAO1 encephalopathies ]]> https://biorxiv.org/content/10.1101/2023.03.27.534359v1?rss=1 40 pathogenic mutations, most are single amino acid substitutions spreading across Go sequence. We perform extensive characterization of Go mutants showing abnormal GTP uptake and hydrolysis, and deficiencies to bind G{beta}{gamma} and RGS19. Plasma membrane localization of Go is decreased for a subset of mutations that leads to epileptic manifestations. Pathogenic mutants massively gain interaction with Ric8A/B proteins, delocalizing them from cytoplasm to Golgi. Being general G-subunit chaperones and binding multiple other proteins, Ric8A/B likely mediate the disease dominance when engaging in neomorphic interactions with pathogenic Go. As the strength of Go-Ric8B interactions correlates with disease severity, our study further identifies an efficient biomarker and predictor for clinical manifestations in GNAO1 encephalopathies. One-Sentence SummaryNeomorphic mutations in Go gain dominant interactions with Ric8A/B, correlating with severity in pediatric encephalopathies. ]]> Solis, G. P. Koval, A. Valnohova, J. Savitsky, M. Katanaev, V. L. 2023-03-27 doi:10.1101/2023.03.27.534359 Cold Spring Harbor Laboratory Press 2023-03-27 <![CDATA[ β-helical protein PerA orchestrates antibiotic uptake across the Caulobacter outer membrane via converging stress signaling systems ]]> https://biorxiv.org/content/10.1101/2023.03.30.534887v1?rss=1 Costafrolaz, J. Panis, G. Vallet, S.-U. Gomariz, M. V. Froehlich, K. Degeorges, L. Viollier, P. 2023-03-30 doi:10.1101/2023.03.30.534887 Cold Spring Harbor Laboratory Press 2023-03-30 <![CDATA[ Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions ]]> https://biorxiv.org/content/10.1101/2023.04.03.535354v1?rss=1 Tai, Y.-H. Engels, D. Locatelli, G. Fecher, C. Theodorou, D. Mueller, S. A. Licht-Mayer, S. Kreutzfeldt, M. Wagner, I. Emmanouilidis, I. Gkotzamani, S.-N. Trovo, L. Kendirli, A. Aljovic, A. Breckwoldt, M. O. Naumann, R. Bareyre, F. M. Mahad, D. Merkler, D. Lichtenthaler, S. F. Kerschensteiner, M. Misgeld, T. 2023-04-03 doi:10.1101/2023.04.03.535354 Cold Spring Harbor Laboratory Press 2023-04-03 <![CDATA[ Controlling morpho-electrophysiological variability of neurons with detailed biophysical models ]]> https://biorxiv.org/content/10.1101/2023.04.06.535923v1?rss=1 Arnaudon, A. Reva, M. Zbili, M. Markram, H. Van Geit, W. Kanari, L. 2023-04-06 doi:10.1101/2023.04.06.535923 Cold Spring Harbor Laboratory Press 2023-04-06 <![CDATA[ SARS-CoV-2 shifts transcription of host gene to increase Spike acylation and boost infectivity ]]> https://biorxiv.org/content/10.1101/2023.04.15.537011v1?rss=1 Mesquita, F. S. Abrami, L. Bracq, L. Panyain, N. Mercier, V. Kunz, B. Chuat, A. Carlevaro-Fita, J. Trono, D. van der Goot, F. G. 2023-04-17 doi:10.1101/2023.04.15.537011 Cold Spring Harbor Laboratory Press 2023-04-17 <![CDATA[ A minimal physical model for curvotaxis driven by curved protein complexes at the cell's leading edge ]]> https://biorxiv.org/content/10.1101/2023.04.19.537490v1?rss=1 Sadhu, R. K. Luciano, M. Xi, W. Torres, C. M. Schroder, M. Blum, C. Tarantola, M. Penic, S. Iglic, A. Beta, C. Steinbock, O. Bodenschatz, E. Ladoux, B. GABRIELE, S. Gov, N. 2023-04-21 doi:10.1101/2023.04.19.537490 Cold Spring Harbor Laboratory Press 2023-04-21 <![CDATA[ K29-linked unanchored polyubiquitin chains disrupt ribosome biogenesis and direct ribosomal proteins to the Intranuclear Quality control compartment (INQ) ]]> https://biorxiv.org/content/10.1101/2023.05.03.539259v1?rss=1 Garadi Suresh, H. Bonneil, E. Albert, B. Dominique, C. Costanzo, M. Pons, C. Masinas, M. P. D. Shuteriqi, E. Shore, D. Henras, A. K. Thibault, P. Boone, C. Andrews, B. J. 2023-05-04 doi:10.1101/2023.05.03.539259 Cold Spring Harbor Laboratory Press 2023-05-04 <![CDATA[ Human Smc5/6 recognises transcription-generated positive DNA supercoils ]]> https://biorxiv.org/content/10.1101/2023.05.04.539344v1?rss=1 Diman, A. Panis, G. Castrogiovanni, C. Prados, J. Baechler, B. Strubin, M. 2023-05-04 doi:10.1101/2023.05.04.539344 Cold Spring Harbor Laboratory Press 2023-05-04 <![CDATA[ Computational principles of adaptive multisensory combination in the Drosophila larva ]]> https://biorxiv.org/content/10.1101/2023.05.04.539474v1?rss=1 Wong, P. Braun, A. Malagarriga, D. Moehlis, J. Moreno Bote, R. Pouget, A. Louis, M. 2023-05-05 doi:10.1101/2023.05.04.539474 Cold Spring Harbor Laboratory Press 2023-05-05 <![CDATA[ Characterizing fibrinolysis under flow conditions: a simplified mesoscale 3D model ]]> https://biorxiv.org/content/10.1101/2023.05.09.539942v1?rss=1 Petkantchin, R. Rousseau, A. Eker, O. Boudjeltia, K. Z. Raynaud, F. Chopard, B. 2023-05-09 doi:10.1101/2023.05.09.539942 Cold Spring Harbor Laboratory Press 2023-05-09 <![CDATA[ The action of physiological and synthetic steroids on the calcium channel CatSper in human sperm ]]> https://biorxiv.org/content/10.1101/2023.05.10.540165v1?rss=1 Wehrli, L. Galdadas, I. Voirol, L. Smiesko, M. Cambet, Y. Jaquet, V. Guerrier, S. Gervasio, F. Nef, S. Rahban, R. 2023-05-10 doi:10.1101/2023.05.10.540165 Cold Spring Harbor Laboratory Press 2023-05-10 <![CDATA[ Chondrogenic Enhancer Landscape of Limb and Axial Skeleton Development ]]> https://biorxiv.org/content/10.1101/2023.05.10.539849v1?rss=1 Darbellay, F. Ramisch, A. Lopez-Delisle, L. Kosicki, M. Visel, A. Andrey, G. 2023-05-11 doi:10.1101/2023.05.10.539849 Cold Spring Harbor Laboratory Press 2023-05-11 <![CDATA[ TCF7L2 is a master regulator of insulin production and processing ]]> https://biorxiv.org/content/10.1101/003202v1?rss=1 Yuedan Zhou Soo-Young Park Jing Su Kathleen Bailey Emilia Ottosson-Laakso Liliya Shcerbina Nikolay Oskolkov Enming Zhang Thomas Thevenin Jo?o Fadista Hedvig Bennet Petter Vikman Nils Wierup Malin Fex Johan Rung Claes Wollheim Marcelo Nobrega Erik Renstr?m Leif Groop Ola Hansson 2014-03-05 doi:10.1101/003202 Cold Spring Harbor Laboratory Press 2014-03-05 <![CDATA[ largeQvalue: A program for calculating FDR estimates with large datasets ]]> https://biorxiv.org/content/10.1101/010074v1?rss=1 Andrew Anand Brown 2014-10-06 doi:10.1101/010074 Cold Spring Harbor Laboratory Press 2014-10-06 <![CDATA[ Pathway based factor analysis of gene expression data produces highly heritable phenotypes that associate with age ]]> https://biorxiv.org/content/10.1101/016154v1?rss=1 Andrew Anand Brown Zhihao Ding Ana Viñuela Dan Glass Leopold Parts Timothy Spector John Winn Richard Durbin 2015-03-06 doi:10.1101/016154 Cold Spring Harbor Laboratory Press 2015-03-06 <![CDATA[ Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder ]]> https://biorxiv.org/content/10.1101/044412v1?rss=1 9 million genetic variants in 9,784 bipolar disorder patients and 30,471 controls, the largest GWAS of BD to date. In this study, to increase power we used ~2,000 lithium-treated cases with a long-term diagnosis of BD from the Consortium on Lithium Genetics, excess controls, and analytic methods optimized for markers on the X-chromosome. In addition to four known loci, results revealed genome-wide significant associations at two novel loci: an intergenic region on 9p21.3 (rs12553324, p = 5.87x10-9; odds ratio = 1.12) and markers within ERBB2 (rs2517959, p = 4.53x10-9; odds ratio = 1.13). No significant X-chromosome associations were detected and X-linked markers explained very little BD heritability. The results add to a growing list of common autosomal variants involved in BD and illustrate the power of comparing well-characterized cases to an excess of controls in GWAS. ]]> Liping Hou Sarah E Bergen Nirmala Akula Jie Song Christina M Hultman Mikael Landen Mazda Adli Martin Alda Raffaella Ardau Barbara Arias Jean-Michel Aubry Lena Backlund Judith A Badner Thomas B Barrett Michael Bauer Bernhard T Baune Frank Bellivier Antonio Benabarre Susanne Bengesser Wade H Berrettini Abesh Kumar Bhattacharjee Joanna M Biernacka Armin Birner Cinnamon S Bloss Clara Brichant-Petitjean Elise T Bui William Byerley Pablo Cervantes Caterina Chillotti Sven Cichon Francesc Colom William Coryell David W Craig Cristiana Cruceanu Piotr M Czerski Tony Davis Alexandre Dayer Franziska Degenh 2016-03-22 doi:10.1101/044412 Cold Spring Harbor Laboratory Press 2016-03-22 <![CDATA[ Genomic epidemiology of global Klebsiella pneumoniae carbapenemase (KPC)-producing E. coli ]]> https://biorxiv.org/content/10.1101/111914v1?rss=1 Stoesser, N. Sheppard, A. E. Peirano, G. Anson, L. W. Pankhurst, L. Sebra, R. Phan, H. T. Kasarskis, A. Mathers, A. J. Peto, T. E. Bradford, P. Motyl, M. The Modernising Medical Microbiology Informatics G, Walker, A. S. Crook, D. W. Pitout, J. 2017-02-27 doi:10.1101/111914 Cold Spring Harbor Laboratory Press 2017-02-27 <![CDATA[ Intragenomic Redistribution Of Host Transcription Factor Binding With Toxoplasma gondii Infection ]]> https://biorxiv.org/content/10.1101/132076v1?rss=1 Ulahannan, N. Suzuki, M. Simoes-Pires, C. A. Wicik, Z. Wijetunga, N. A. Croken, M. M. Bhattacharyya, S. Johnston, A. D. Kong, Y. Maqbool, S. B. Verma, A. Greally, J. M. 2017-04-28 doi:10.1101/132076 Cold Spring Harbor Laboratory Press 2017-04-28 <![CDATA[ MATAM: Reconstruction Of Phylogenetic Marker Genes From Short Sequencing Reads In Metagenomes ]]> https://biorxiv.org/content/10.1101/141176v1?rss=1 Pericard, P. Dufresne, Y. Blanquart, S. Touzet, H. 2017-05-23 doi:10.1101/141176 Cold Spring Harbor Laboratory Press 2017-05-23 <![CDATA[ Mosaic Chromosomal Aneuploidy Detection By Sequencing (MAD-seq) ]]> https://biorxiv.org/content/10.1101/142299v1?rss=1 Kong, Y. Berko, E. R. Marcketta, A. Maqbool, S. B. Simoes-Pires, C. A. Kronn, D. F. Ye, K. Q. Suzuki, M. Auton, A. Greally, J. M. 2017-05-25 doi:10.1101/142299 Cold Spring Harbor Laboratory Press 2017-05-25 <![CDATA[ p.E152K-STIM1 mutation deregulates Ca2+ signaling contributing to chronic pancreatitis. ]]> https://biorxiv.org/content/10.1101/2020.01.22.916254v1?rss=1 Burgos, M. Phillipe, R. Antigny, F. Buscaglia, P. Masson, E. Mukherjee, S. Dubar, P. Le Marechal, C. Campeotto, F. Lebonvallet, N. Frieden, M. Llopis, J. Domingo, B. Stathopulos, P. B. Ikura, M. Brooks, W. Guida, W. Chen, J.-M. Ferec, C. Capiod, T. Mignen, O. 2020-01-23 doi:10.1101/2020.01.22.916254 Cold Spring Harbor Laboratory Press 2020-01-23 <![CDATA[ Validity of dynamical analysis to characterize heart rate and oxygen consumption during effort tests ]]> https://biorxiv.org/content/10.1101/2020.02.29.971119v1?rss=1 Mongin, D. Chabert, C. Uribe Caparros, A. Collado, A. Hermand, E. Hue, O. Alvero Cruz, J. R. Courvoisier, D. S. 2020-03-03 doi:10.1101/2020.02.29.971119 Cold Spring Harbor Laboratory Press 2020-03-03 <![CDATA[ The complex relationship between effort and heart rate: a hint from dynamical analysis ]]> https://biorxiv.org/content/10.1101/2020.03.01.971929v1?rss=1 Mongin, D. Chabert, C. Uribe Caparros, A. Vico Guzman, J. F. Hue, O. Alvero Cruz, J. R. Courvoisier, D. S. 2020-03-03 doi:10.1101/2020.03.01.971929 Cold Spring Harbor Laboratory Press 2020-03-03 <![CDATA[ Adipose-tissue derived signals control bone remodelling. ]]> https://biorxiv.org/content/10.1101/2020.03.02.972711v1?rss=1 Fu, H. Madel, M.-B. Pierroz, D. Schiffrin, M. Winkler, C. Wilson, A. Pochon, C. Toffoli, B. Jouzeau, J.-Y. Gilardi, F. Ferrari, S. Bonnet, N. BLIN-WAKKACH, C. Desvergne, B. MOULIN, D. 2020-03-03 doi:10.1101/2020.03.02.972711 Cold Spring Harbor Laboratory Press 2020-03-03 <![CDATA[ Regulation of light harvesting in Chlamydomonas: two protein phosphatases are involved in state transitions ]]> https://biorxiv.org/content/10.1101/2020.03.31.018721v1?rss=1 Cariti, F. Chazaux, M. Legendre-Lefebvre, L. Longoni, P. Ghysels, B. Johnson, X. Goldschmidt-Clermont, M. 2020-04-01 doi:10.1101/2020.03.31.018721 Cold Spring Harbor Laboratory Press 2020-04-01 <![CDATA[ Investigating the origin and consequences of endogenous default options in repeated economic choices. ]]> https://biorxiv.org/content/10.1101/2020.04.15.042689v1?rss=1 Couto, J. van Maanen, L. Lebreton, M. 2020-04-16 doi:10.1101/2020.04.15.042689 Cold Spring Harbor Laboratory Press 2020-04-16 <![CDATA[ Regulation of intracellular energy supplies by cell cycle kinetics using a single cell approach. ]]> https://biorxiv.org/content/10.1101/2020.04.24.054643v1?rss=1 Galichon, P. Lannoy, M. Li, L. Vandermeersch, S. Valerius, M. T. Hadchouel, J. Bonventre, J. V. 2020-04-25 doi:10.1101/2020.04.24.054643 Cold Spring Harbor Laboratory Press 2020-04-25 <![CDATA[ Intraflagellar transport during the assembly of flagella of different length in Trypanosoma brucei isolated from tsetse flies ]]> https://biorxiv.org/content/10.1101/2020.05.14.095216v1?rss=1 Bertiaux, E. Mallet, A. Rotureau, B. Bastin, P. 2020-05-15 doi:10.1101/2020.05.14.095216 Cold Spring Harbor Laboratory Press 2020-05-15 <![CDATA[ Database for drug metabolism and comparisons, NICEdrug.ch, aids discovery and design ]]> https://biorxiv.org/content/10.1101/2020.05.28.120782v1?rss=1 MohammadiPeyhani, H. Chiappino-Pepe, A. Haddadi, K. Hafner, J. Hadadi, N. Hatzimanikatis, V. 2020-05-30 doi:10.1101/2020.05.28.120782 Cold Spring Harbor Laboratory Press 2020-05-30 <![CDATA[ Examining and fine-tuning the selection of glycan compositions with GlyConnect Compozitor ]]> https://biorxiv.org/content/10.1101/2020.06.03.131979v1?rss=1 Robin, T. Mariethoz, J. Lisacek, F. 2020-06-03 doi:10.1101/2020.06.03.131979 Cold Spring Harbor Laboratory Press 2020-06-03 <![CDATA[ Functional synchronization between hippocampal sEEG, parietal ECoG and scalp EEG during a verbal working memory task. ]]> https://biorxiv.org/content/10.1101/2020.06.05.136515v1?rss=1 Dimakopoulos, V. S. Boran, E. Hilfiker, P. Stieglitz, L. Grunwald, T. Megevand, P. Sarnthein, J. 2020-06-06 doi:10.1101/2020.06.05.136515 Cold Spring Harbor Laboratory Press 2020-06-06 <![CDATA[ Mechanisms Coordinating Ribosomal Protein Gene Transcription in Response to Stress ]]> https://biorxiv.org/content/10.1101/2020.06.09.143263v1?rss=1 Zencir, S. Dilg, D. Rueda, M. P. Shore, D. Albert, B. 2020-06-10 doi:10.1101/2020.06.09.143263 Cold Spring Harbor Laboratory Press 2020-06-10 <![CDATA[ Evidence accumulation determines conscious access ]]> https://biorxiv.org/content/10.1101/2020.07.10.196659v1?rss=1 Michael Pereira Pierre Megevand Mi Xue Tan Wenwen Chang Shuo Wang Ali Rezai Margitta Seeck Marco Corniola Shahan Momjian Fosco Bernasconi Olaf Blanke Nathan Faivre 2020-07-11 doi:10.1101/2020.07.10.196659 Cold Spring Harbor Laboratory Press 2020-07-11 <![CDATA[ CglB adhesins secreted at bacterial focal adhesions mediate gliding motility ]]> https://biorxiv.org/content/10.1101/2020.07.22.216333v1?rss=1 Islam, S. T. My, L. Jolivet, N. Y. Belgrave, A. M. Fleuchot, B. Brasseur, G. Faure, L. M. Sharma, G. Lemon, D. J. Saidi, F. Fiche, J.-B. Bratton, B. P. Singer, M. Garza, A. G. Nollmann, M. Shaevitz, J. W. Mignot, T. 2020-07-22 doi:10.1101/2020.07.22.216333 Cold Spring Harbor Laboratory Press 2020-07-22 <![CDATA[ Local structure of DNA toroids reveals curvature-dependent intermolecular forces ]]> https://biorxiv.org/content/10.1101/2020.07.23.211979v1?rss=1 Barberi, L. Livolant, F. Leforestier, A. Lenz, M. 2020-07-23 doi:10.1101/2020.07.23.211979 Cold Spring Harbor Laboratory Press 2020-07-23 <![CDATA[ Radiation-induced cell cycle perturbations: acomputational tool validated with flow-cytometrydata ]]> https://biorxiv.org/content/10.1101/2020.07.29.226480v1?rss=1 LONATI, L. Barbieri, S. Guardamagna, I. Ottolenghi, A. Baiocco, G. 2020-07-29 doi:10.1101/2020.07.29.226480 Cold Spring Harbor Laboratory Press 2020-07-29 <![CDATA[ Molecular motion and tridimensional nanoscale localization of kindlin control integrin activation in focal adhesions ]]> https://biorxiv.org/content/10.1101/2020.08.06.239731v1?rss=1 Orre, T. Karatas, Z. Kastberger, B. Cabriel, C. Boettcher, R. T. Leveque-Fort, S. Sibarita, J.-B. Faessler, R. Wehrle-Haller, B. Rossier, O. Giannone, G. 2020-08-06 doi:10.1101/2020.08.06.239731 Cold Spring Harbor Laboratory Press 2020-08-06 <![CDATA[ Pinching the cortex of live cells reveals thickness instabilities caused by Myosin II motors ]]> https://biorxiv.org/content/10.1101/2020.09.28.316729v1?rss=1 LAPLAUD, V. Levernier, N. Pineau, J. San-Roman, M. Barbier, L. Saez, P. J. Lennon-Dumenil, A.-M. Vargas, P. Kruse, K. DU ROURE, O. Piel, M. Heuvingh, J. 2020-09-29 doi:10.1101/2020.09.28.316729 Cold Spring Harbor Laboratory Press 2020-09-29 <![CDATA[ Worrying drives cell migration in mechanically unrestrained environments ]]> https://biorxiv.org/content/10.1101/2020.11.09.372912v1?rss=1 Welf, E. S. Driscoll, M. K. Sapoznik, E. Murali, V. S. Weems, A. D. Roh-Johnson, M. Dean, K. M. Fiolka, R. P. Danuser, G. 2020-11-09 doi:10.1101/2020.11.09.372912 Cold Spring Harbor Laboratory Press 2020-11-09 <![CDATA[ Full species-wide leaf and seed ionomic diversity of Arabidopsis thaliana ]]> https://biorxiv.org/content/10.1101/2020.11.09.373282v1?rss=1 Campos, A. C. A. L. van Dijk, W. F. A. Ramakrishna, P. Giles, T. Korte, P. Douglas, A. Smith, P. Salt, D. E. 2020-11-10 doi:10.1101/2020.11.09.373282 Cold Spring Harbor Laboratory Press 2020-11-10 <![CDATA[ Bifocal tACS Enhances Visual Motion Discrimination by Modulating Phase Amplitude Coupling Between V1 and V5 Regions ]]> https://biorxiv.org/content/10.1101/2020.11.16.382267v1?rss=1 Salamanca, R. Raffin, E. Zandvliet, S. Seeber, M. Michel, C. Sauseng, P. Huxlin, K. R. Hummel, F. 2020-11-17 doi:10.1101/2020.11.16.382267 Cold Spring Harbor Laboratory Press 2020-11-17 <![CDATA[ Redox protein Memo1 coordinates FGF23-driven signaling and small Rho-GTPases in the mouse kidney ]]> https://biorxiv.org/content/10.1101/2020.12.04.402511v1?rss=1 Bartos, K. Ramakrishnan, S. K. Braga-Lagache, S. Haenzi, B. Durussel, F. Prakash Sridharan, A. Zhu, Y. Sheehan, D. Hynes, N. E. Bonny, O. Moor, M. B. 2020-12-04 doi:10.1101/2020.12.04.402511 Cold Spring Harbor Laboratory Press 2020-12-04 <![CDATA[ Astrocytic VMAT2 in the developing prefrontal cortex is required for normal grooming behavior in mice ]]> https://biorxiv.org/content/10.1101/2021.01.27.428434v1?rss=1 Bezzi, P. Petrelli, F. Zehnder, T. Pucci, L. Cali, C. Bondiolotti, B. M. Molinero Perez, A. Dallerac, G. Deglon, N. Giros, B. Magara, F. Magrassi, L. Mothet, J.-P. Simmler, L. 2021-01-27 doi:10.1101/2021.01.27.428434 Cold Spring Harbor Laboratory Press 2021-01-27 <![CDATA[ Allogeneic CAR-invariant Natural Killer T Cells Exert Potent Antitumor Effects Through Host CD8 T cell Cross-Priming ]]> https://biorxiv.org/content/10.1101/2021.02.03.428987v1?rss=1 Simonetta, F. Lohmeyer, J. K. Hirai, T. Maas-Bauer, K. Alvarez, M. Wenokur, A. S. Baker, J. Aalipour, A. Ji, X. Haile, S. Mackall, C. L. Negrin, R. S. 2021-02-03 doi:10.1101/2021.02.03.428987 Cold Spring Harbor Laboratory Press 2021-02-03 <![CDATA[ S-acylation targets ORAI1 channels to lipid rafts for efficient Ca2+ signaling by T cell receptors at the immune synapse ]]> https://biorxiv.org/content/10.1101/2021.02.03.429577v1?rss=1 Carreras-Sureda, A. Abrami, L. JI-Hee, K. Frieden, M. Didier, M. van der Goot, F. G. Demaurex, N. 2021-02-04 doi:10.1101/2021.02.03.429577 Cold Spring Harbor Laboratory Press 2021-02-04 <![CDATA[ Specialization of actin isoforms derived from the loss of key interactions with regulatory factors ]]> https://biorxiv.org/content/10.1101/2021.02.09.430555v1?rss=1 Boiero Sanders, M. Toret, C. Antkowiak, A. Guillotin, A. Robinson, R. C. Michelot, A. 2021-02-11 doi:10.1101/2021.02.09.430555 Cold Spring Harbor Laboratory Press 2021-02-11 <![CDATA[ Early mechanisms of whisker development: Prdm1 and its regulation in whisker development and evolutionary loss ]]> https://biorxiv.org/content/10.1101/2021.03.11.433122v1?rss=1 Manti, P. G. Darbellay, F. Leleu, M. Moret, B. Cuennet, J. Droux, F. Stoudmann, M. Mancini, G. Hautier, A. Barrandon, Y. 2021-03-12 doi:10.1101/2021.03.11.433122 Cold Spring Harbor Laboratory Press 2021-03-12 <![CDATA[ Emotion Recognition in a Multi-Componential Framework: The Role of Physiology ]]> https://biorxiv.org/content/10.1101/2021.04.08.438559v1?rss=1 Menetrey, M. Q. Mohammadi, G. Leitao, J. Vuilleumier, P. 2021-04-09 doi:10.1101/2021.04.08.438559 Cold Spring Harbor Laboratory Press 2021-04-09 <![CDATA[ Imaging protein conformational space in liquid water ]]> https://biorxiv.org/content/10.1101/2021.04.30.442083v1?rss=1 De Pace, C. Acosta-Gutierrez, S. Ing, G. Marchello, G. Pilotto, S. Werner, F. Wilkinson, N. Gervasio, F. Ruiz-Perez, L. Battaglia, G. 2021-04-30 doi:10.1101/2021.04.30.442083 Cold Spring Harbor Laboratory Press 2021-04-30 <![CDATA[ ACTIVATION LOOP PHOSPHORYLATION OF A NON-RD RECEPTOR KINASE INITIATES PLANT INNATE IMMUNE SIGNALING ]]> https://biorxiv.org/content/10.1101/2021.05.01.442257v1?rss=1 Bender, K. W. Couto, D. Kadota, Y. Macho, A. P. Sklenar, J. Bjornson, M. Petriello, A. Font Farre, M. Schwessinger, B. Ntoukakis, V. Stransfeld, L. Jones, A. M. E. Menke, F. L. zipfel, c. 2021-05-01 doi:10.1101/2021.05.01.442257 Cold Spring Harbor Laboratory Press 2021-05-01 <![CDATA[ DELAY OF GERMINATION 6, encoding the ANAC060 transcription factor, inhibits seed dormancy ]]> https://biorxiv.org/content/10.1101/2021.05.03.442418v1?rss=1 Song, S. He, H. Guhl, K. Veldkamp, M. v. B. Buijs, G. Willems, L. A. J. Bentsink, L. 2021-05-03 doi:10.1101/2021.05.03.442418 Cold Spring Harbor Laboratory Press 2021-05-03 <![CDATA[ ApoE4 disrupts interaction of sortilin with fatty acid-binding protein 7 essential to promote lipid signaling ]]> https://biorxiv.org/content/10.1101/2021.05.20.444938v1?rss=1 Asaro, A. Sinha, R. Bakun, M. Kalnytska, O. Carlo-Spiewok, A.-S. Rubel, T. Rozeboom, A. Dadlez, M. Kaminska, B. Aronica, E. Malik, A. R. Willnow, T. 2021-05-20 doi:10.1101/2021.05.20.444938 Cold Spring Harbor Laboratory Press 2021-05-20 <![CDATA[ baredSC: Bayesian Approach to Retrieve Expression Distribution of Single-Cell ]]> https://biorxiv.org/content/10.1101/2021.05.26.445740v1?rss=1 Lopez-Delisle, L. Delisle, J.-B. 2021-05-26 doi:10.1101/2021.05.26.445740 Cold Spring Harbor Laboratory Press 2021-05-26 <![CDATA[ Antisense-mediated repression of SAGA-dependent genes involves the HIR histone chaperone ]]> https://biorxiv.org/content/10.1101/2021.07.05.451174v1?rss=1 Soudet, J. Beyrouthy, N. Pastucha, A. M. Maffioletti, A. Bakir, Z. Stutz, F. 2021-07-06 doi:10.1101/2021.07.05.451174 Cold Spring Harbor Laboratory Press 2021-07-06 <![CDATA[ Systematic in vivo interrogation identifies novel enhancers and silencers associated to Atrial Fibrillation ]]> https://biorxiv.org/content/10.1101/2021.07.14.452222v1?rss=1 Victorino, J. Rollan, I. Rouco, R. Adan, J. Manzanares, M. 2021-07-14 doi:10.1101/2021.07.14.452222 Cold Spring Harbor Laboratory Press 2021-07-14 <![CDATA[ A shared brain system forming confidence judgment across cognitive domains ]]> https://biorxiv.org/content/10.1101/2021.09.17.460809v1?rss=1 Rouault, M. Lebreton, M. Pessiglione, M. 2021-09-20 doi:10.1101/2021.09.17.460809 Cold Spring Harbor Laboratory Press 2021-09-20 <![CDATA[ Multi-parameter optical imaging of immune cell activity in chimeric antigen receptor T-cell and checkpoint blockade therapies ]]> https://biorxiv.org/content/10.1101/2021.10.11.463603v1?rss=1 Xie, J. Rami, F. E. Zhou, K. Simonetta, F. Chen, Z. Zheng, X. Chen, M. Balakrishnan, P. B. Dai, S.-Y. Murty, S. Alam, I. S. Baker, J. Negrin, R. S. Gambhir, S. S. Rao, J. 2021-10-13 doi:10.1101/2021.10.11.463603 Cold Spring Harbor Laboratory Press 2021-10-13 <![CDATA[ Brain endothelial antigen presentation detains CD8+ T cells at the blood-brain barrier leading to its breakdown ]]> https://biorxiv.org/content/10.1101/2021.10.12.464035v1?rss=1 Aydin, S. Pareja, J. Schallenberg, V. M. Klopstein, A. Gruber, T. Page, N. Kaba, E. Deutsch, U. Johnson, A. Schenk, M. Merkler, D. Engelhardt, B. 2021-10-13 doi:10.1101/2021.10.12.464035 Cold Spring Harbor Laboratory Press 2021-10-13 <![CDATA[ Different armpits under my new nose: olfactory sex but not gender affects implicit measures of embodiment ]]> https://biorxiv.org/content/10.1101/2021.12.16.472829v1?rss=1 Roel Lesur, M. Stussi, Y. Bertrand, P. Delplanque, S. Lenggenhager, B. 2021-12-17 doi:10.1101/2021.12.16.472829 Cold Spring Harbor Laboratory Press 2021-12-17 <![CDATA[ GPR55 in B cells limits atherosclerosis development and regulates plasma cell maturation ]]> https://biorxiv.org/content/10.1101/2021.12.20.473518v1?rss=1 Guillamat-Prats, R. Hering, D. Rami, M. Haerdtner, C. Sanovito, D. Rinne, P. Bindila, L. Hristov, M. Pagano, S. Vuilleumier, N. Schmid, S. Janjic, A. Enard, W. Weber, C. Maegdefessel, L. Faussner, A. Hilgendorf, I. Steffens, S. 2021-12-21 doi:10.1101/2021.12.20.473518 Cold Spring Harbor Laboratory Press 2021-12-21 <![CDATA[ Distinct cDC subsets co-operate in CD40 agonist response while suppressive microenvironments and lack of antigens subvert efficacy ]]> https://biorxiv.org/content/10.1101/2021.12.25.474021v1?rss=1 Murgaski, A. Kiss, M. Van Damme, H. Kancheva, D. Vanmeerbeek, I. Keirsse, J. Hadadi, E. Brughmans, J. Arnouk, S. M. Hamouda, A. E. I. Debraekeleer, A. Bosteels, V. Elkrim, Y. Boon, L. Hoves, S. Vandamme, N. Deschoemaeker, S. Janssens, S. Garg, A. D. Schmittnaegel, M. Ries, C. H. Laoui, D. 2021-12-26 doi:10.1101/2021.12.25.474021 Cold Spring Harbor Laboratory Press 2021-12-26 <![CDATA[ Ethylene augments root hypoxia tolerance through amelioration of reactive oxygen species and growth cessation ]]> https://biorxiv.org/content/10.1101/2022.01.21.477196v1?rss=1 Liu, Z. Hartman, S. van Veen, H. Zhang, H. Leeggangers, H. A. Martopawiro, S. Bosman, F. de Deugd, F. Su, P. Hummel, M. Rankenberg, T. Hassall, K. Bailey-Serres, J. Theodoulou, F. Voesenek, L. A. Sasidharan, R. 2022-01-23 doi:10.1101/2022.01.21.477196 Cold Spring Harbor Laboratory Press 2022-01-23 <![CDATA[ Translational reprogramming in response to accumulating stressors ensures critical threshold levels of Hsp90 for mammalian life ]]> https://biorxiv.org/content/10.1101/2022.02.11.480086v1?rss=1 Bhattacharya, K. Maiti, S. Zahoran, S. Weidenauer, L. Hany, D. Wider, D. Bernasconi, L. Quadroni, M. Collart, M. Picard, D. 2022-02-11 doi:10.1101/2022.02.11.480086 Cold Spring Harbor Laboratory Press 2022-02-11 <![CDATA[ Sleep duration and brain structure - phenotypic associations and genotypic covariance ]]> https://biorxiv.org/content/10.1101/2022.02.15.480501v1?rss=1 8 hours) was more strongly associated with smaller relative volumes, thinner cortex and larger ventricles than even very short sleep (< 5 hours), but effect sizes were modest. People with larger ICV reported longer sleep (7.5 hours), so not correcting for ICV yielded longer durations associated with maximal volume. Controlling for socioeconomic status, body mass index and depression symptoms did not alter the associations. Genetic analyses showed that genes related to longer sleep in short sleepers were related to shorter sleep in long sleepers. This may indicate a genetically controlled homeostatic regulation of sleep duration. Mendelian randomization analyses did not suggest sleep duration to have a causal impact on brain structure in the analyzed datasets. The findings challenge the notion that habitual short sleep is negatively related to brain structure. Significance statementAccording to consensus recommendations, adults should sleep between 7 and 9 hours to optimize their health. We found that sleeping less than the recommended amount was associated with greater regional brain volumes relative to intracranial volume, and very short sleep was only weakly related to smaller volumes. Genetic analyses did not show causal effects of sleep duration on brain structure. Taken together, the results suggest that habitual short sleep is not an important contributor to lower brain volumes in adults on a group level, and that large individual dfferences in sleep need likely exist. ]]> Fjell, A. Sorensen, O. Wang, Y. Amlien, I. K. Baare, W. Bartres-Faz, D. Bertram, L. Boraxbekk, C.-J. Brandmaier, A. Demuth, I. Drevon, C. A. Ebmeier, K. Ghisletta, P. Kievit, R. A. Kuhn, S. A. Madsen, K. S. Mowinckel, A. M. Nyberg, L. Sexton, C. Sole-Padulles, C. Vidal-Pineiro, D. Wagner, G. Watne, L. O. Walhovd, K. B. 2022-02-17 doi:10.1101/2022.02.15.480501 Cold Spring Harbor Laboratory Press 2022-02-17 <![CDATA[ Targeting the fronto-parietal network using multifocal personalized transcranial alternating current stimulation to enhance motor sequence learning in healthy older adults ]]> https://biorxiv.org/content/10.1101/2022.02.16.480660v1?rss=1 Draaisma, L. R. Wessel, M. J. Moyne, M. Morishita, T. Hummel, F. C. 2022-02-17 doi:10.1101/2022.02.16.480660 Cold Spring Harbor Laboratory Press 2022-02-17 <![CDATA[ The structure of insulin granule core determines secretory capacity being reduced in type-2 diabetes ]]> https://biorxiv.org/content/10.1101/2022.02.22.481455v1?rss=1 Barghouth, M. Jiang, X. Nagao, M. Chen, N. Yang, D. Ye, Y. Luan, C. Gomez, M. Blom, A. M. Wollheim, C. Eliasson, L. Renstrom, E. Zhang, E. 2022-02-23 doi:10.1101/2022.02.22.481455 Cold Spring Harbor Laboratory Press 2022-02-23 <![CDATA[ Cryo-EM structure of the Rhodobaca bogoriensis RC-LH1-PufX dimeric complex at 2.9 angstrom ]]> https://biorxiv.org/content/10.1101/2022.02.25.481955v1?rss=1 Semchonok, D. A. Siponen, M. I. Toeting, C. Charras, Q. Kyrilis, F. L. Sadian, Y. Jungas, C. Kastritis, P. L. 2022-02-26 doi:10.1101/2022.02.25.481955 Cold Spring Harbor Laboratory Press 2022-02-26 <![CDATA[ Emotion schema effects on associative memory differ across emotion categories at the behavioural, physiological and neural level ]]> https://biorxiv.org/content/10.1101/2022.03.04.482789v1?rss=1 Riegel, M. Wypych, M. Wierzba, M. Szczepanik, M. Jednorog, K. Vuilleumier, P. Marchewka, A. 2022-03-07 doi:10.1101/2022.03.04.482789 Cold Spring Harbor Laboratory Press 2022-03-07 <![CDATA[ DNA methylation dynamics during stress-response in woodland strawberry (Fragaria vesca) ]]> https://biorxiv.org/content/10.1101/2022.03.04.483002v1?rss=1 Lopez, M.-E. Roquis, D. Becker, C. Denoyes, B. Bucher, E. 2022-03-05 doi:10.1101/2022.03.04.483002 Cold Spring Harbor Laboratory Press 2022-03-05 <![CDATA[ The little skate genome and the evolutionary emergence of wing-like fin appendages ]]> https://biorxiv.org/content/10.1101/2022.03.21.485123v1?rss=1 Marletaz, F. de la Calle-Mustienes, E. Acemel, R. D. Nakamura, T. Paliou, C. Naranjo, S. Martinez-Garcia, P. M. Cases, I. Sleight, V. A. Hirschberger, C. Marcet-Houben, M. Navon, D. Andrescavage, A. Skvortsova, K. Duckett, P. E. Gonzalez-Rajal, A. Bogdanovic, O. Gibcus, J. H. Yang, L. Gallardo-Fuentes, L. Sospedra, I. Lopez-Rios, J. Darbellay, F. Visel, A. Dekker, J. Shubin, N. Gabaldon, T. Tena, J. J. Lupianez, D. G. Rokhsar, D. S. Gomez-Skarmeta, J. L. 2022-03-22 doi:10.1101/2022.03.21.485123 Cold Spring Harbor Laboratory Press 2022-03-22 <![CDATA[ Knockout of TSPO delays and reduces amyloid, Tau, astrocytosis and behavioral dysfunctions in Alzheimer's disease. ]]> https://biorxiv.org/content/10.1101/2022.03.26.485919v1?rss=1 Ceyzeriat, K. Meyer, L. Bouteldja, F. Tsartsalis, S. Amosse, Q. Middleton, R. J. Liu, G.-J. Banati, R. B. Zilli, T. Garibotto, V. Millet, P. Tournier, B. B. 2022-03-27 doi:10.1101/2022.03.26.485919 Cold Spring Harbor Laboratory Press 2022-03-27 <![CDATA[ KIF21B binds Myosin Va for Spine Entry and regulates Actin Dynamics to control Homeostatic Synaptic Downscaling ]]> https://biorxiv.org/content/10.1101/2022.05.04.490582v1?rss=1 Gromova, K. V. Thies, E. Duerst, C. D. Stajano, D. Schweizer, M. Mikhaylova, M. Gee, C. E. Kneussel, M. 2022-05-04 doi:10.1101/2022.05.04.490582 Cold Spring Harbor Laboratory Press 2022-05-04 <![CDATA[ In silico investigation of cytochrome bc1 molecular inhibition mechanism against Trypanosoma cruzi. ]]> https://biorxiv.org/content/10.1101/2022.06.01.494283v1?rss=1 Muscat, S. Grasso, G. Scapozza, L. Danani, A. 2022-06-01 doi:10.1101/2022.06.01.494283 Cold Spring Harbor Laboratory Press 2022-06-01 <![CDATA[ Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections ]]> https://biorxiv.org/content/10.1101/2022.06.28.497982v1?rss=1 Fries, M. Brown, T. Jolicoeur, C. Abram, P. Boudreau-Pinsonneault, C. Javed, A. Cayouette, M. 2022-06-29 doi:10.1101/2022.06.28.497982 Cold Spring Harbor Laboratory Press 2022-06-29 <![CDATA[ Heterogeneity of RNA editing in mesothelioma and how RNA editing enzyme ADAR2 affects mesothelioma cell growth, response to chemotherapy and tumor microenvironment ]]> https://biorxiv.org/content/10.1101/2022.07.12.499727v1?rss=1 Hariharan, A. Qi, W. Rehrauer, H. Wu, L. Ronner, M. Wipplinger, M. Kresoja-Rakic, J. Sun, S. Oton-Gonzales, L. Sculco, M. Serre-Beinier, V. Meiller, C. Blanquart, C. Fonteneau, J.-F. Vrugt, B. Rueschoff, J. H. Opitz, I. JEAN, D. de Perrot, M. Felley-Bosco, E. 2022-07-13 doi:10.1101/2022.07.12.499727 Cold Spring Harbor Laboratory Press 2022-07-13 <![CDATA[ Integrated Analysis of T cell Repertoire and Transcriptome Identifies Mechanisms of Regulatory T cell (Treg) Suppression of Acute Graft-versus-Host-Disease ]]> https://biorxiv.org/content/10.1101/2022.07.26.501553v1?rss=1 Lohmeyer, J. K. Hirai, T. Turkoz, M. Buhler, S. Ramos, T. L. Koehler, N. Baker, J. Ji, X. Villard, J. Chalandon, Y. Simonetta, F. Negrin, R. S. 2022-07-28 doi:10.1101/2022.07.26.501553 Cold Spring Harbor Laboratory Press 2022-07-28 <![CDATA[ Relaxed targeting rules allow PIWI-clade Argonaute proteins to silence ever-mutating transposons ]]> https://biorxiv.org/content/10.1101/2022.08.04.502788v1?rss=1 Gainetdinov, I. Cecchini, K. Vega-Badillo, J. Bagci, A. Colpan, C. Arif, A. Wu, P.-H. Zamore, P. D. 2022-08-05 doi:10.1101/2022.08.04.502788 Cold Spring Harbor Laboratory Press 2022-08-05 <![CDATA[ Single-cell Transcriptomics Reveal Different Maturation Stages and Sublineages Commitment of Human Thymic Invariant Natural Killer T cells ]]> https://biorxiv.org/content/10.1101/2022.08.10.503443v1?rss=1 Maas-Bauer, K. Acharya, S. Baker, J. Lewis, D. B. Negrin, R. S. Simonetta, F. 2022-08-11 doi:10.1101/2022.08.10.503443 Cold Spring Harbor Laboratory Press 2022-08-11 <![CDATA[ Network-informed discovery of multidrug combinations for ERα+/HER2-/PI3Kα-mutant breast cancer ]]> https://biorxiv.org/content/10.1101/2022.08.30.505871v1?rss=1 Hany, D. Zoetemelk, M. Bhattacharya, K. Nowak-Sliwinska, P. Picard, D. 2022-09-03 doi:10.1101/2022.08.30.505871 Cold Spring Harbor Laboratory Press 2022-09-03 <![CDATA[ HLA variants and TCR diversity against SARS-CoV-2 in the pre-COVID-19 era ]]> https://biorxiv.org/content/10.1101/2022.09.14.507948v1?rss=1 Buhler, S. Calderin, Z. Bettens, F. Schaefer, A. Dantin, C. Ansari, M. Mamez, A.-C. Masouridi-Levrat, S. Chalandon, Y. Ferrari-Lacraz, S. Villard, J. 2022-09-14 doi:10.1101/2022.09.14.507948 Cold Spring Harbor Laboratory Press 2022-09-14 <![CDATA[ Robust eIF4B levels undermine invasive growth and immune evasion mechanisms in murine triple negative breast cancer models. ]]> https://biorxiv.org/content/10.1101/2022.09.16.508318v1?rss=1 Smith, R. Diba, L. Z. D. Z. D. Srinivasan, A. Zollo, R. A. Ossevoort, T. He, Q. Colligan, S. H. Dolan, M. Vedire, Y. Sultana, T. Venkatesh, M. Arora, A. P. Gawlak, S. Washington, D. Brackett, C. Yao, S. Ebos, J. M. L. Abrams, S. I. Barbi, J. Walker, S. E. 2022-09-18 doi:10.1101/2022.09.16.508318 Cold Spring Harbor Laboratory Press 2022-09-18 <![CDATA[ The identity of Argyria lacteella (Fabricius, 1794) (Lepidoptera, Pyraloidea, Crambinae), synonyms, and related species using morphology and DNA capture in type specimens ]]> https://biorxiv.org/content/10.1101/2022.10.10.511518v1?rss=1 Landry, B. Bilat, J. Hayden, J. Solis, M. A. Lees, D. C. Alvarez, N. Leger, T. Gauthier, J. 2022-10-12 doi:10.1101/2022.10.10.511518 Cold Spring Harbor Laboratory Press 2022-10-12 <![CDATA[ De novo protein design by inversion of the AlphaFold structure prediction network ]]> https://biorxiv.org/content/10.1101/2022.12.13.520346v1?rss=1 Goverde, C. Wolf, B. Khakzad, H. Rosset, S. Correia, B. E. 2022-12-15 doi:10.1101/2022.12.13.520346 Cold Spring Harbor Laboratory Press 2022-12-15 <![CDATA[ Rational design of chemically controlled antibodies and protein therapeutics ]]> https://biorxiv.org/content/10.1101/2022.12.22.521584v1?rss=1 Marchand, A. Bonati, L. Shui, S. Scheller, L. Gainza, P. Rosset, S. Georgeon, S. Tang, L. Correia, B. 2022-12-23 doi:10.1101/2022.12.22.521584 Cold Spring Harbor Laboratory Press 2022-12-23 <![CDATA[ Robotically-induced auditory-verbal hallucinations: combining self-monitoring and strong perceptual priors ]]> https://biorxiv.org/content/10.1101/2022.12.22.521663v1?rss=1 Orepic, P. Bernasconi, F. Faggella, M. Faivre, N. Blanke, O. 2022-12-23 doi:10.1101/2022.12.22.521663 Cold Spring Harbor Laboratory Press 2022-12-23 <![CDATA[ Tumor Microenvironment Cellular Crosstalk Predicts Response to Adoptive TIL Therapy in Melanoma ]]> https://biorxiv.org/content/10.1101/2022.12.23.519261v1?rss=1 Barras, D. Ghisoni, E. Chiffelle, J. Orcurto, A. Dagher, J. Fahr, N. Benedetti, F. Crespo, I. Zimmermann, S. Duran, R. Imbimbo, M. Ochoa De Olza, M. Navarro, B. Homiscko, K. Bobisse, S. Labes, D. Tsourti, Z. Andriakopoulou, C. Herrera, F. Grimm, A. Morotti, M. Petremand, R. Dummer, R. Berthod, G. Bassani-Sternberg, M. Schaefer, N. Prior, J. O. Matter, M. Demartines, N. Aedo, V. Dromain, C. Tissot, S. Corria-Osorio, J. Kandalaft, L. E. Pittet, M. Gottardo, R. Sempoux, C. Michelin, O. Dafni, U. Trueb, L. Harari, A. Dangaj Laniti, D. Coukos, G. 2022-12-23 doi:10.1101/2022.12.23.519261 Cold Spring Harbor Laboratory Press 2022-12-23 <![CDATA[ Deadenylation rate is not a major determinant of RNA degradation in yeast ]]> https://biorxiv.org/content/10.1101/2023.01.16.524186v1?rss=1 Audebert, L. Feuerbach, F. Decourty, L. Namane, A. Permal, E. Badis, G. Saveanu, C. 2023-01-17 doi:10.1101/2023.01.16.524186 Cold Spring Harbor Laboratory Press 2023-01-17 <![CDATA[ Conformational plasticity and allosteric communication networks govern Shelterin protein TPP1 binding to human telomerase ]]> https://biorxiv.org/content/10.1101/2023.02.02.526655v1?rss=1 Aureli, S. Raniolo, S. Limongelli, V. 2023-02-03 doi:10.1101/2023.02.02.526655 Cold Spring Harbor Laboratory Press 2023-02-03 <![CDATA[ At the core of salinity: convergent and divergent transcriptome response pathways to neutral and alkaline salinity in natural populations of Arabidopsis thaliana ]]> https://biorxiv.org/content/10.1101/2023.02.05.527167v1?rss=1 Almira-Casellas, M. J. Busoms, S. Perez-Martin, L. Escola, G. Lopez-Valinas, A. Garcia-Molina, A. Llugany, M. Poschenrieder, C. 2023-02-08 doi:10.1101/2023.02.05.527167 Cold Spring Harbor Laboratory Press 2023-02-08 <![CDATA[ IL-33 drives polyfunctionality and antitumor activity of a unique ST2+ NK cell population ]]> https://biorxiv.org/content/10.1101/2023.02.14.528486v1?rss=1 Eberhardt, A. Blanc, E. Picant, V. Alcazer, V. Rocca, Y. Ardin, M. Voissiere, A. Onodi, F. Rodriguez, C. Tonon, L. Estavoyer, B. Moudombi, L. Charrier, E. Wang, X. Stojanovic, A. Rau, T. Tredan, O. Treilleux, I. Michallet, M.-C. Valladeau-Guilemond, J. Marcais, A. Walzer, T. Krebs, P. Cerwenka, A. Hubert, M. Caux, C. Bendriss-Vermare, N. 2023-02-15 doi:10.1101/2023.02.14.528486 Cold Spring Harbor Laboratory Press 2023-02-15 <![CDATA[ Shared inflammatory glial cell signature after brain injury, revealed by spatial, temporal and cell-type-specific profiling of the murine cerebral cortex ]]> https://biorxiv.org/content/10.1101/2023.02.24.529840v1?rss=1 Koupourtidou, C. Schwarz, V. Aliee, H. Frerich, S. Fischer-Sternjak, J. Bocchi, R. Simon-Ebert, T. Dichgans, M. Goetz, M. Theis, F. J. Ninkovic, J. 2023-02-27 doi:10.1101/2023.02.24.529840 Cold Spring Harbor Laboratory Press 2023-02-27 <![CDATA[ Alterations of the TGFb-sequestration complex member ADAMTSL1 levels are associated with muscular defects and rhabdomyosarcoma aggressiveness ]]> https://biorxiv.org/content/10.1101/2023.03.07.531559v1?rss=1 Juban, G. Bertrand-Chapel, A. Meyer, S. Kneppers, A. E. M. Huchede, P. Gallerne, C. Benayoun, R. Cohen, E. Lopez-Gonzalez, A. Larbi, S. B. Creveaux, M. Vaille, L. Bouvier, A. Theodore, M. Broutier, L. Dutour, A. Cordier-Bussat, M. Blay, J.-Y. Streichenberger, N. Picard, C. Corradini, N. Allamand, V. Castets, P. Mounier, R. CASTETS, M. 2023-03-08 doi:10.1101/2023.03.07.531559 Cold Spring Harbor Laboratory Press 2023-03-08 <![CDATA[ The Smc5/6 complex belongs to a novel class of evolutionary-constrained restriction factors and is antagonized by all mammalian hepatitis B virus X proteins ]]> https://biorxiv.org/content/10.1101/202671v1?rss=1 Filleton, F. Abdul, F. Gerossier, L. Paturel, A. Hall, J. Strubin, M. Etienne, L. 2017-10-13 doi:10.1101/202671 Cold Spring Harbor Laboratory Press 2017-10-13 <![CDATA[ PWO1 interacts with PcG proteins and histones to regulate Arabidopsis flowering and development. ]]> https://biorxiv.org/content/10.1101/226183v1?rss=1 Hohenstatt, M. L. Mikulski, P. Komarynets, O. Klose, C. Kycia, I. Jeltsch, A. Farrona, S. Schubert, D. 2017-11-28 doi:10.1101/226183 Cold Spring Harbor Laboratory Press 2017-11-28 <![CDATA[ Sequence-directed action of RSC remodeler and pioneer factors positions +1 nucleosome to facilitate transcription ]]> https://biorxiv.org/content/10.1101/266072v1?rss=1 Kubik, S. O'Dubhuir, E. de Jonge, W. Mattarocci, S. Albert, B. Falcone, J.-L. Bruzzone, M. J. Holstege, F. C. P. Shore, D. 2018-02-16 doi:10.1101/266072 Cold Spring Harbor Laboratory Press 2018-02-16 <![CDATA[ Extensive cellular heterogeneity of X inactivation revealed by single-cell allele-specific expression in human fibroblasts. ]]> https://biorxiv.org/content/10.1101/298984v1?rss=1 stamoulis, g. Garieri, M. Falconnet, E. Ribaux, P. borel, c. Santoni, F. A. Antonarakis, S. 2018-04-10 doi:10.1101/298984 Cold Spring Harbor Laboratory Press 2018-04-10 <![CDATA[ Fine-tuning cellular levels of DprA ensures transformant fitness in the human pathogen Streptococcus pneumoniae ]]> https://biorxiv.org/content/10.1101/314575v1?rss=1 Johnston, C. Mortier-Barriere, I. Khemici, V. Polard, P. 2018-05-04 doi:10.1101/314575 Cold Spring Harbor Laboratory Press 2018-05-04 <![CDATA[ Guanabenz treatment improves Oculopharyngeal muscular dystrophy phenotype ]]> https://biorxiv.org/content/10.1101/375758v1?rss=1 Malerba, A. Roth, F. Harish, P. Dhiab, J. Lu-Nguyen, N. Cappellari, O. Jarmin, S. Mahoudeau, A. Ythier, V. Laine, J. Negroni, E. Abgueguen, E. Simonelig, M. Guedat, P. Mouly, V. Butler-Browne, G. Voisset, C. Dickson, G. Trollet, C. 2018-07-24 doi:10.1101/375758 Cold Spring Harbor Laboratory Press 2018-07-24 <![CDATA[ Hierarchical structure and memory retrieval mechanisms in agreement attraction ]]> https://biorxiv.org/content/10.1101/422139v1?rss=1 Franck, J. Wagers, M. 2018-09-19 doi:10.1101/422139 Cold Spring Harbor Laboratory Press 2018-09-19 <![CDATA[ The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity ]]> https://biorxiv.org/content/10.1101/472290v1?rss=1 Echeverria, P. C. Bhattacharya, K. Joshi, A. Wang, T. Picard, D. 2018-11-16 doi:10.1101/472290 Cold Spring Harbor Laboratory Press 2018-11-16 <![CDATA[ Genetic resistance to DEHP-induced transgenerational endocrine disruption ]]> https://biorxiv.org/content/10.1101/474155v1?rss=1 Stenz, L. Rahban, R. Prados, J. Nef, S. Paoloni-Giacobino, A. 2018-11-19 doi:10.1101/474155 Cold Spring Harbor Laboratory Press 2018-11-19 <![CDATA[ Integrative haplotype estimation with sub-linear complexity ]]> https://biorxiv.org/content/10.1101/493403v1?rss=1 Delaneau, O. Zagury, J.-F. Robinson, M. R. Marchini, J. Dermitzakis, E. 2018-12-13 doi:10.1101/493403 Cold Spring Harbor Laboratory Press 2018-12-13 <![CDATA[ Intracortical neural activity distal to seizure-onset-areas predicts human focal seizures ]]> https://biorxiv.org/content/10.1101/529966v1?rss=1 Proix, T. Aghagolzadeh, M. Madsen, J. R. Cosgrove, R. Eskandar, E. Hochberg, L. R. Cash, S. S. Truccolo, W. 2019-01-24 doi:10.1101/529966 Cold Spring Harbor Laboratory Press 2019-01-24 <![CDATA[ Impact of an intra-abdominal cooling device during open kidney transplantation in pigs ]]> https://biorxiv.org/content/10.1101/568402v1?rss=1 Longchamp, A. Meier, R. P. H. Colucci, N. Balaphas, A. Orci, L. Nastasi, A. Longchamp, G. Moll, S. Klauser, A. Pascual, M. Lazeyras, F. Corpataux, J.-M. Bühler, L. 2019-03-05 doi:10.1101/568402 Cold Spring Harbor Laboratory Press 2019-03-05 <![CDATA[ Colony entropy - Allocation of goods in ant colonies ]]> https://biorxiv.org/content/10.1101/572032v1?rss=1 Greenwald, E. Eckmann, J.-P. Feinerman, O. 2019-03-08 doi:10.1101/572032 Cold Spring Harbor Laboratory Press 2019-03-08 <![CDATA[ Transcriptional maintenance of cortical somatostatin interneuron subtype identity during migration ]]> https://biorxiv.org/content/10.1101/593285v1?rss=1 Munguba, H. Nikouei, K. Hochgerner, H. Oberst, P. Kouznetsova, A. Ryge, J. Bastista-Brito, R. Munoz-Manchado, A. B. Close, J. Linnarsson, S. Hjerling Leffler, J. 2019-03-31 doi:10.1101/593285 Cold Spring Harbor Laboratory Press 2019-03-31 <![CDATA[ Decreased confidence in loss-avoidance contexts is a primary meta-cognitive bias of human reinforcement learning ]]> https://biorxiv.org/content/10.1101/593368v1?rss=1 Ting, C.-C. Palminteri, S. Engelmann, J. B. Lebreton, M. 2019-04-04 doi:10.1101/593368 Cold Spring Harbor Laboratory Press 2019-04-04 <![CDATA[ Mitotic exit is controlled during anaphase by an Aurora B-Cyclin B1/Cdk1 crosstalk ]]> https://biorxiv.org/content/10.1101/606517v1?rss=1 Maiato, H. Afonso, O. Cheeseman, L. Ferreira, L. Morais-de-Sa, E. 2019-04-12 doi:10.1101/606517 Cold Spring Harbor Laboratory Press 2019-04-12 <![CDATA[ Novel Rhabdovirus and an almost complete drain fly transcriptome recovered from two independent contaminations of clinical samples. ]]> https://biorxiv.org/content/10.1101/645325v1?rss=1 Brito, F. Manni, M. Laubscher, F. Schibler, M. Hartley, M.-A. Keitel, K. Mlaganile, T. d'Acremont, V. Cordey, S. Kaiser, L. Zdobnov, E. M. 2019-05-23 doi:10.1101/645325 Cold Spring Harbor Laboratory Press 2019-05-23 <![CDATA[ Fine chromatin-driven mechanism of transcription interference by antisense noncoding transcription ]]> https://biorxiv.org/content/10.1101/649434v1?rss=1 Gill, J. K. Maffioletti, A. Garcia-Molinero, V. Stutz, F. Soudet, J. 2019-05-24 doi:10.1101/649434 Cold Spring Harbor Laboratory Press 2019-05-24 <![CDATA[ Timing and original features of flagellum assembly in trypanosomes during development in the tsetse fly ]]> https://biorxiv.org/content/10.1101/728964v1?rss=1 Lemos, M. Mallet, A. Bertiaux, E. Imbert, A. Rotureau, B. Bastin, P. 2019-08-08 doi:10.1101/728964 Cold Spring Harbor Laboratory Press 2019-08-08 <![CDATA[ Loss of Bacterial Cell Pole Stabilization in Caulobacter crescentus Sensitizes to Outer Membrane Stress and Peptidoglycan-Directed Antibiotics ]]> https://biorxiv.org/content/10.1101/784066v1?rss=1 Vallet, S.-U. Hansen, L. H. Bistrup, F. C. Chapalay, J. B. Chambon, M. Turcatti, G. Viollier, P. H. Kirkpatrick, C. L. 2019-09-26 doi:10.1101/784066 Cold Spring Harbor Laboratory Press 2019-09-26 <![CDATA[ CLICK-enabled analogues reveal pregnenolone interactomes in cancer and immune cells ]]> https://biorxiv.org/content/10.1101/800649v1?rss=1 Roy, S. Sipthorp, J. Mahata, B. Pramanik, J. Hennrich, M. L. Gavin, A.-C. Ley, S. V. Teichmann, S. 2019-10-16 doi:10.1101/800649 Cold Spring Harbor Laboratory Press 2019-10-16 <![CDATA[ A novel experimental system reveals immunoregulatory responses as mediators of persistent orthohantavirus infections in a rodent reservoir host ]]> https://biorxiv.org/content/10.1101/831214v1?rss=1 Strandin, T. Smura, T. Ahola, P. Aaltonen, K. Sironen, T. Hepojoki, J. Eckerle, I. Ulrich, R. Vapalahti, O. Kipar, A. Forbes, K. 2019-11-05 doi:10.1101/831214 Cold Spring Harbor Laboratory Press 2019-11-05 <![CDATA[ Shared anomalies in cortical reading networks in Chinese and French dyslexic children ]]> https://biorxiv.org/content/10.1101/834945v1?rss=1 Feng, X. Altarelli, I. Monzalvo, K. Ding, G. Ramus, F. Shu, H. Dehaene, S. Meng, X. Dehaene-Lambertz, G. 2019-11-08 doi:10.1101/834945 Cold Spring Harbor Laboratory Press 2019-11-08 <![CDATA[ T-cell immunoglobulin and mucin (TIM) contributes to Hantaan virus entry into human airway epithelial cells ]]> https://biorxiv.org/content/10.1101/872317v1?rss=1 Mayor, J. Torriani, G. Zimmer, G. Rothenberger, S. Engler, O. 2019-12-11 doi:10.1101/872317 Cold Spring Harbor Laboratory Press 2019-12-11 <![CDATA[ A key regulatory protein for flagellum length control in stable flagella ]]> https://biorxiv.org/content/10.1101/872952v1?rss=1 Atkins, M. Tyc, J. Shafiq, S. Ahmed, M. Bertiaux, E. De castro neto, A. L. Sunter, J. Bastin, P. Dean, S. Vaughan, S. 2019-12-11 doi:10.1101/872952 Cold Spring Harbor Laboratory Press 2019-12-11 <![CDATA[ Hi-Fi fMRI: High-resolution, fast-sampled and sub-second whole-brain functional MRI at 3T in humans ]]> https://biorxiv.org/content/10.1101/2023.05.13.540663v1?rss=1 Franceschiello, B. Rumac, S. Hilbert, T. Nau, M. Dziadosz, M. Degano, G. Roy, C. W. Gaglianese, A. Petri, G. Yerly, J. Stuber, M. Kober, T. van Heeswijk, R. B. Murray, M. M. Fornari, E. 2023-05-15 doi:10.1101/2023.05.13.540663 Cold Spring Harbor Laboratory Press 2023-05-15 <![CDATA[ Dual control of host actin polymerization by a Legionella effector pair ]]> https://biorxiv.org/content/10.1101/2023.05.15.540800v1?rss=1 Pillon, M. Michard, C. Baïlo, N. Bougnon, J. Picq, K. Dubois, O. Andrea, C. Attaiech, L. Daubin, V. Jarraud, S. Kay, E. Doublet, P. 2023-05-15 doi:10.1101/2023.05.15.540800 Cold Spring Harbor Laboratory Press 2023-05-15 <![CDATA[ Modeling and Simulation of Neocortical Micro- and Mesocircuitry. Part II: Physiology and Experimentation ]]> https://biorxiv.org/content/10.1101/2023.05.17.541168v1?rss=1 Isbister, J. B. Ecker, A. Pokorny, C. Bolanos-Puchet, S. Egas Santander, D. Arnaudon, A. Awile, O. Barros-Zulaica, N. Blanco Alonso, J. Boci, E. Chindemi, G. Courcol, J.-D. Damart, T. Delemontex, T. Dietz, A. Ficarelli, G. Gevaert, M. Herttuainen, J. Ivaska, G. Ji, W. Keller, D. King, J. Kumbhar, P. Lapere, S. Litvak, P. Mandge, D. Muller, E. B. Pereira, F. Planas, J. Ranjan, R. Reva, M. Romani, A. Rössert, C. Schürmann, F. Sood, V. Teska, A. Tuncel, A. Van Geit, W. Wolf, M. Markram, H. Ramaswamy, S. Reimann, M. W. 2023-05-17 doi:10.1101/2023.05.17.541168 Cold Spring Harbor Laboratory Press 2023-05-17 <![CDATA[ Akt Drives TGF-beta-induced Over-secretion of DKK1 and Impairment of Cystic Fibrosis Airway Epithelium Polarity ]]> https://biorxiv.org/content/10.1101/2023.05.22.541703v1?rss=1 Idris, T. Bachmann, M. Bacchetta, M. Wehrle-Haller, B. Chanson, M. Badaoui, M. 2023-05-22 doi:10.1101/2023.05.22.541703 Cold Spring Harbor Laboratory Press 2023-05-22 <![CDATA[ ChAdOx1 COVID vaccines express RBD open prefusion SARS-CoV-2 spikes on the cell surface ]]> https://biorxiv.org/content/10.1101/2023.05.22.541685v1?rss=1 Zhang, P. Gilbert, S. Radecke, J. Ni, T. Mendonca, L. Zhu, Y. Howe, A. Shah, P. M. Sheng, Y. Krebs, A.-S. Duyvesteyn, H. M. E. Allen, E. Lambe, T. Bissett, C. Morris, S. Spencer, A. Stuart, D. I. 2023-05-24 doi:10.1101/2023.05.22.541685 Cold Spring Harbor Laboratory Press 2023-05-24 <![CDATA[ Overexpression of an apple broad range agglutinating lectin does not promote in planta resistance to fire blight and bacterial wilt. ]]> https://biorxiv.org/content/10.1101/2023.05.23.541687v1?rss=1 Bodelot, A. Chavonet, E. Brisset, M.-N. Dousset, N. Ravon, E. Heintz, C. Berthome, R. Zaffuto, M. Kempf, M. Foulon, M. Marion, E. Vergne, E. Degrave, A. 2023-05-24 doi:10.1101/2023.05.23.541687 Cold Spring Harbor Laboratory Press 2023-05-24 <![CDATA[ CLICK-chemoproteomics and molecular dynamics simulation reveals pregnenolone targets and their binding conformations in Th2 cells ]]> https://biorxiv.org/content/10.1101/2023.05.23.541892v1?rss=1 Roy, S. Roy, S. Mahata, B. Pramanik, J. Hennrich, M. L. Gavin, A.-C. Teichmann, S. A. 2023-05-24 doi:10.1101/2023.05.23.541892 Cold Spring Harbor Laboratory Press 2023-05-24 <![CDATA[ Thalamic contributions to psychosis susceptibility: Evidence from co-activation patterns accounting for intra-seed spatial variability (μCAPs) ]]> https://biorxiv.org/content/10.1101/2023.05.23.541896v1?rss=1 Delavari, F. Sandini, C. Kojovic, N. Saccaro, L. F. Eliez, S. Van De Ville, D. Bolton, T. 2023-05-24 doi:10.1101/2023.05.23.541896 Cold Spring Harbor Laboratory Press 2023-05-24 <![CDATA[ Birth of immunity in early life: stepwise emergence of resistance and immunity to complex molecular parasites via progressively degenerating hyperparasites ]]> https://biorxiv.org/content/10.1101/2023.05.25.542273v1?rss=1 Conrad, B. Curran, J. A. Iseli, C. Pirovino, M. 2023-05-25 doi:10.1101/2023.05.25.542273 Cold Spring Harbor Laboratory Press 2023-05-25 <![CDATA[ Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release ]]> https://biorxiv.org/content/10.1101/2023.05.26.542102v1?rss=1 Zhou, X. Stine, C. Prada, P. O. Fusca, D. Assoumou, K. Dernic, J. Bhat, M. A. Achanta, A. S. Johnson, J. C. Jadhav, S. Bader, C. A. Steuernagel, L. Ravotto, L. Benke, D. Weber, B. Stoeber, M. Kloppenburg, P. Bruening, J. C. Bruchas, M. R. Patriarchi, T. 2023-05-26 doi:10.1101/2023.05.26.542102 Cold Spring Harbor Laboratory Press 2023-05-26 <![CDATA[ Epigenetic and transcriptional landscape of heat-stress memory in woodland strawberry (Fragaria vesca) ]]> https://biorxiv.org/content/10.1101/2023.05.26.542514v1?rss=1 Lopez, M. E. Denoyes, B. Bucher, E. 2023-05-29 doi:10.1101/2023.05.26.542514 Cold Spring Harbor Laboratory Press 2023-05-29 <![CDATA[ The actin cytoskeleton plays multiple roles in structural color formation in butterfly wing scales ]]> https://biorxiv.org/content/10.1101/2023.06.01.542791v1?rss=1 Lloyd, V. J. Burg, S. L. Harizanova, J. Hill, O. Enciso-Romero, J. Cooper, R. L. Flenner, S. Longo, E. Greving, I. Nadeau, N. J. Parnell, A. J. 2023-06-01 doi:10.1101/2023.06.01.542791 Cold Spring Harbor Laboratory Press 2023-06-01 <![CDATA[ An abundant future for quagga mussels in deep European lakes ]]> https://biorxiv.org/content/10.1101/2023.05.31.543086v1?rss=1 Kraemer, B. M. Boudet, S. Burlakova, L. E. Haltiner, L. Ibelings, B. W. Karatayev, A. Y. Karatayev, V. A. Rossbacher, S. Stoeckli, R. Straile, D. Piet, S. 2023-06-04 doi:10.1101/2023.05.31.543086 Cold Spring Harbor Laboratory Press 2023-06-04 <![CDATA[ Influence of colour vision on attention to, and impression of, complex aesthetic images ]]> https://biorxiv.org/content/10.1101/2023.06.14.544891v1?rss=1 Hiramatsu, C. Takashima, T. Sakaguchi, H. Chen, X. Tajima, S. Seno, T. Kawamura, S. 2023-06-14 doi:10.1101/2023.06.14.544891 Cold Spring Harbor Laboratory Press 2023-06-14 <![CDATA[ Auditory cortex anatomy reflects multilingual phonological experience ]]> https://biorxiv.org/content/10.1101/2023.06.16.545298v1?rss=1 Kepinska, O. Dalboni da Rocha, J. Tuerk, C. Hervais-Adelman, A. Bouhali, F. Green, D. Price, C. J. Golestani, N. 2023-06-16 doi:10.1101/2023.06.16.545298 Cold Spring Harbor Laboratory Press 2023-06-16 <![CDATA[ The T766M-EGFR lung cancer mutation promotes tumor growth by exploiting newfound assembly mechanisms in ligand-free EGFR oligomers ]]> https://biorxiv.org/content/10.1101/2023.06.16.545259v1?rss=1 Martin-Fernandez, M. L. Iyer, S. Needham, S. R. Galgadas, I. Davis, B. M. Roberts, S. K. Man, R. C. Zanetti-Domingues, L. C. Clarke, D. T. Fruhwirth, G. O. Parker, P. J. Rolfe, D. J. Gervasio, F. L. 2023-06-19 doi:10.1101/2023.06.16.545259 Cold Spring Harbor Laboratory Press 2023-06-19 <![CDATA[ The ALOG domain defines a new family of plant-specific transcription factors acting during Arabidopsis flower development ]]> https://biorxiv.org/content/10.1101/2023.06.21.545689v1?rss=1 Rieu, P. Beretta, V. M. Caselli, F. Thevenon, E. Lucas, J. Rizk, M. Franchini, E. Dumas, R. Nanao, M. H. Kater, M. M. Dumas, R. Zubieta, C. Parcy, F. Gregis, V. 2023-06-22 doi:10.1101/2023.06.21.545689 Cold Spring Harbor Laboratory Press 2023-06-22 <![CDATA[ PINK1 Deficiency Alters Muscle Stem Cell Fate Decision And Muscle Regenerative Capacity. ]]> https://biorxiv.org/content/10.1101/2023.06.23.546123v1?rss=1 Cairns, G. Thumiah-Mootoo, M. Abbasi, M. R. Racine, J. Lariovov, N. Prola, A. Khacho, M. Burelle, Y. 2023-06-25 doi:10.1101/2023.06.23.546123 Cold Spring Harbor Laboratory Press 2023-06-25 <![CDATA[ Cell Type- and Tissue-specific Enhancers in Craniofacial Development ]]> https://biorxiv.org/content/10.1101/2023.06.26.546603v1?rss=1 View larger version (36K): org.highwire.dtl.DTLVardef@7595a9org.highwire.dtl.DTLVardef@1b48b81org.highwire.dtl.DTLVardef@32fe86org.highwire.dtl.DTLVardef@1e41fed_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Rajderkar, S. S. Paraiso, K. Amaral, M. L. Kosicki, M. Cook, L. Darbellay, F. Spurrell, C. Osterwalder, M. Zhu, Y. Wu, H. Afzal, S. Y. Blow, M. Kelman, G. Barozzi, I. Fukuda-Yuzawa, Y. Akiyama, J. A. Afzal, V. Tran, S. Plajzer-Frick, I. Novak, C. S. Kato, M. Hunter, R. D. von Maydell, K. Wang, A. Lin, L. Preissl, S. Lisgo, S. Ren, B. Dickel, D. E. Pennacchio, L. A. Visel, A. 2023-06-26 doi:10.1101/2023.06.26.546603 Cold Spring Harbor Laboratory Press 2023-06-26 <![CDATA[ Extracellular vesicle-mediated trafficking of developmental cues is altered during human brain disease ]]> https://biorxiv.org/content/10.1101/2023.06.27.546646v1?rss=1 View larger version (40K): org.highwire.dtl.DTLVardef@1dad15aorg.highwire.dtl.DTLVardef@e699ccorg.highwire.dtl.DTLVardef@17b371borg.highwire.dtl.DTLVardef@5efa7b_HPS_FORMAT_FIGEXP M_FIG C_FIG Graphical abstract(left) EV uptake mechanism varies depending on the receiving cell type; NPCs transport neuron EVs (nEVs) and astrocyte EVs (aEVs) to the nucleus, astrocytes localize progenitor EVs (pEVs) to the cytoplasm, and neurons retain pEVs and aEVs along the plasma membrane. (right) Cerebral organoids (COs) from progressive Myoclonus Epilepsy Type I (EPM1) patients release EVs lacking key proteins in neurodevelopment and proteins necessary for EV biogenesis and release. Illustration created using BioRender. ]]> Pipicelli, F. Forero, A. Moser, S. Di Matteo, F. Baumann, N. Graetz, C. Gonzalez Pisfil, M. Bekjarova, Z. Pfaffl, M. Canafoglia, L. Puetz, B. Kielkowski, P. Cernilogar, F. Maccarrone, G. Jabaudon, D. Di Giaimo, R. Cappello, S. 2023-06-27 doi:10.1101/2023.06.27.546646 Cold Spring Harbor Laboratory Press 2023-06-27 <![CDATA[ Developmental molecular controls over arealization of descending cortical motor pathways ]]> https://biorxiv.org/content/10.1101/2023.06.29.546438v1?rss=1 Abe, P. Lavalley, A. Morassut, I. Klingler, E. Santinha, A. J. Platt, R. J. Jabaudon, D. 2023-06-30 doi:10.1101/2023.06.29.546438 Cold Spring Harbor Laboratory Press 2023-06-30 <![CDATA[ Speech prosody enhances the neural processing of syntax ]]> https://biorxiv.org/content/10.1101/2023.07.03.547482v1?rss=1 Degano, G. Donhauser, P. Gwilliams, L. Merlo, P. Golestani, N. 2023-07-03 doi:10.1101/2023.07.03.547482 Cold Spring Harbor Laboratory Press 2023-07-03 <![CDATA[ A Brain-Wide Map of Neural Activity during Complex Behaviour ]]> https://biorxiv.org/content/10.1101/2023.07.04.547681v1?rss=1 International Brain Lab, Benson, B. Benson, J. Birman, D. Bonacchi, N. Carandini, M. Catarino, J. A. Chapuis, G. A. Churchland, A. K. Dan, Y. Dayan, P. DeWitt, E. E. Engel, T. A. Fabbri, M. Faulkner, M. Fiete, I. R. Findling, C. Freitas-Silva, L. Gercek, B. Harris, K. D. Hausser, M. Hofer, S. B. Hu, F. Hubert, F. Huntenburg, J. M. Khanal, A. Krasniak, C. Langdon, C. Lau, P. Y. P. Mainen, Z. F. Meijer, G. T. Miska, N. J. Mrsic-Flogel, T. D. Noel, J.-P. Nylund, K. Pan-Vazquez, A. Pouget, A. Rossant, C. Roth, N. Schaeffer, R. Schartner, M. Shi, Y. Socha 2023-07-04 doi:10.1101/2023.07.04.547681 Cold Spring Harbor Laboratory Press 2023-07-04 <![CDATA[ Brain-wide representations of prior information in mouse decision-making ]]> https://biorxiv.org/content/10.1101/2023.07.04.547684v1?rss=1 Findling, C. Hubert, F. International Brain Laboratory, Acerbi, L. Benson, B. Benson, J. Birman, D. Bonacchi, N. Carandini, M. Catarino, J. A. Chapuis, G. A. Churchland, A. K. Dan, Y. DeWitt, E. E. Engel, T. A. Fabbri, M. Faulkner, M. Fiete, I. R. Freitas-Silva, L. Gercek, B. Harris, K. D. Hausser, M. Hofer, S. B. Hu, F. Huntenburg, J. M. Khanal, A. Krasniak, C. Langdon, C. Latham, P. E. Lau, P. Y. P. Meijer, G. T. Miska, N. J. Mrsic-Flogel, T. D. Noel, J.-P. Nylund, K. Paninski, L. Pan-Vazquez, A. Pillow, J. Rossant, C. Roth, N. Schaeffer, R. Schartn 2023-07-04 doi:10.1101/2023.07.04.547684 Cold Spring Harbor Laboratory Press 2023-07-04 <![CDATA[ Evolution of circadian behavioral plasticity through cis-regulatory divergence of a neuropeptide gene ]]> https://biorxiv.org/content/10.1101/2023.07.05.547553v1?rss=1 Shahandeh, M. P. Abuin, L. Lescuyer De Decker, L. Cergneux, J. Koch, R. Nagoshi, E. Benton, R. 2023-07-05 doi:10.1101/2023.07.05.547553 Cold Spring Harbor Laboratory Press 2023-07-05 <![CDATA[ Patterns of recombination in snakes reveal a tug of war between PRDM9 and promoter-like features ]]> https://biorxiv.org/content/10.1101/2023.07.11.548536v1?rss=1 Hoge, C. R. de Manuel, M. Mahgoub, M. Okami, N. Fuller, Z. L. Banerjee, S. Baker, Z. Mcnulty, M. Andolfatto, P. Macfarlan, T. S. Schumer, M. Tzika, A. C. Przeworski, M. 2023-07-11 doi:10.1101/2023.07.11.548536 Cold Spring Harbor Laboratory Press 2023-07-11 <![CDATA[ Epitope Engineered Human Haematopoietic Stem Cells are Shielded from CD123-targeted Immunotherapy ]]> https://biorxiv.org/content/10.1101/2023.07.11.547391v1?rss=1 Marone, R. Landmann, E. Devaux, A. Lepore, R. Seyres, D. Zuin, J. Burgold, T. Engdahl, C. Capoferri, G. DellAglio, A. Larrue, C. Simonetta, F. Rositzka, J. Rhiel, M. Andrieux, G. Gallagher, D. Schroeder, M. Wiederkehr, A. Sinopoli, A. Do Sacramento, V. Haydn, A. Garcia-Prat, L. Divsalar, C. Camus, A. Xu, L. Bordoli, L. Schwede, T. Porteus, M. Tamburini Bonnefoy, J. Corn, J. E. Cathomen, T. Cornu, T. I. Urlinger, S. Jeker, L. T. 2023-07-12 doi:10.1101/2023.07.11.547391 Cold Spring Harbor Laboratory Press 2023-07-12 <![CDATA[ Longstanding auditory sensory and semantic differences in preterm born children ]]> https://biorxiv.org/content/10.1101/2023.07.12.548657v1?rss=1 Retsa, C. Turpin, H. Geiser, E. Ansermet, F. Muller-Nix, C. Murray, M. M. 2023-07-12 doi:10.1101/2023.07.12.548657 Cold Spring Harbor Laboratory Press 2023-07-12 <![CDATA[ Mycobacterium tuberculosis infection associated immune perturbations correlate with antiretroviral immunity ]]> https://biorxiv.org/content/10.1101/2023.07.14.548872v1?rss=1 Tepekule Mueller, B. Joerimann, L. Schenkel, C. D. Opitz, L. Tschumi, J. Wolfensberger, R. Neumann, K. Kusejko, K. Zeeb, M. Boeck, L. Kaelin, M. Notter, J. Furrer, H. Hoffmann, M. Hirsch, H. H. Calmy, A. Cavassini, M. Labhardt, N. D. Bernasconi, E. Metzner, K. J. Braun, D. L. Guenthard, H. F. Kouyos, R. D. Duffy, F. Nemeth, J. the Swiss HIV Cohort Study, 2023-07-18 doi:10.1101/2023.07.14.548872 Cold Spring Harbor Laboratory Press 2023-07-18 <![CDATA[ A multistage Plasmodium CRL4-WIG1 ubiquitin ligase is critical for the formation of functional microtubule organisation centres in microgametocytes ]]> https://biorxiv.org/content/10.1101/2023.07.19.549332v1?rss=1 Rashpa, R. Smith, C. Artavanis-Tsakonas, K. Brochet, M. 2023-07-19 doi:10.1101/2023.07.19.549332 Cold Spring Harbor Laboratory Press 2023-07-19 <![CDATA[ A Taxonomically-informed Mass Spectrometry Search Tool for Microbial Metabolomics Data ]]> https://biorxiv.org/content/10.1101/2023.07.20.549584v1?rss=1 60,000 microbial monocultures, users can search known and unknown MS/MS spectra and link them to their respective microbial producers via MS/MS fragmentation patterns. Identification of microbial-derived metabolites and relative producers, without a priori knowledge, will vastly enhance the understanding of microorganisms role in ecology and human health. ]]> Zuffa, S. Schmid, R. Bauermeister, A. P. Gomes, P. W. Caraballo-Rodriguez, A. M. El Abiead, Y. Aron, A. T. Gentry, E. C. Zemlin, J. Meehan, M. J. Avalon, N. E. Cichewicz, R. H. Buzun, E. Carrillo Terrazas, M. Hsu, C.-Y. Oles, R. Vasquez Ayala, A. Zhao, J. Chu, H. Kuijpers, M. C. M. Jackrel, S. L. Tugizimana, F. Nephali, L. P. Dubery, I. A. Madala, N. E. Moreira, E. A. Costa-Lotufo, L. V. Lopes, N. P. Rezende-Teixeira, P. Jimenez, P. C. Rimal, B. Patterson, A. D. Traxler, M. F. Pessotti, R. d. C. Alvarado-Villalobos, D. Tamayo-Castillo, G. Chaverri, P. Escud 2023-07-20 doi:10.1101/2023.07.20.549584 Cold Spring Harbor Laboratory Press 2023-07-20 <![CDATA[ Membrane mechanics dictate axonal morphology and function ]]> https://biorxiv.org/content/10.1101/2023.07.20.549958v1?rss=1 Griswold, J. M. Bonilla-Quintana, M. Pepper, R. Lee, C. T. Raychaudhuri, S. Ma, S. Gan, Q. Syed, S. Zhu, C. Bell, M. Suga, M. Yamaguchi, Y. Chereau, R. Nagerl, V. Knott, G. W. Rangamani, P. Watanabe, S. 2023-07-21 doi:10.1101/2023.07.20.549958 Cold Spring Harbor Laboratory Press 2023-07-21 <![CDATA[ Cdc42 mobility and membrane flows regulate fission yeast cell shape and survival ]]> https://biorxiv.org/content/10.1101/2023.07.21.550042v1?rss=1 Rutkowski, D. M. Vincenzetti, V. Vavylonis, D. Martin, S. G. 2023-07-21 doi:10.1101/2023.07.21.550042 Cold Spring Harbor Laboratory Press 2023-07-21 <![CDATA[ Laser microdissection, proteomics and multiplex immunohistochemistry: a bumpy ride into the study of paraffin-embedded fetal and pediatric lung tissues. ]]> https://biorxiv.org/content/10.1101/2023.07.25.550475v1?rss=1 Cardoso dos Santos, L. M. Ventura Avila, Y. Schvartz, D. Rougemont, A.-L. Bochaton-Piallat, M.-L. Ruchonnet-Metrailler, I. 2023-07-27 doi:10.1101/2023.07.25.550475 Cold Spring Harbor Laboratory Press 2023-07-27 <![CDATA[ Connexin 41.8 mediates the correct temporal induction of haematopoietic stem and progenitor cells ]]> https://biorxiv.org/content/10.1101/2023.07.27.550806v1?rss=1 Petzold, T. Watanabe, M. BERTRAND, J. Y. 2023-07-28 doi:10.1101/2023.07.27.550806 Cold Spring Harbor Laboratory Press 2023-07-28 <![CDATA[ Hippocampal timestamp for goals ]]> https://biorxiv.org/content/10.1101/2023.07.27.550892v1?rss=1 Montagrin, A. Croote, D. E. Preti, M. G. Lerman, L. Baxter, M. G. Schiller, D. 2023-07-28 doi:10.1101/2023.07.27.550892 Cold Spring Harbor Laboratory Press 2023-07-28 <![CDATA[ An essential protease, FtsH, influences daptomycin resistance acquisition in Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2023.07.31.551240v1?rss=1 View larger version (32K): org.highwire.dtl.DTLVardef@12ff3adorg.highwire.dtl.DTLVardef@127044aorg.highwire.dtl.DTLVardef@8ab082org.highwire.dtl.DTLVardef@14a4afc_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Nair, Z. J. Gao, I. H. Firras, A. Chong, K. K. L. Choo, P. Y. Pethe, K. Kline, K. A. 2023-07-31 doi:10.1101/2023.07.31.551240 Cold Spring Harbor Laboratory Press 2023-07-31 <![CDATA[ Self-regulation of attention in children in a virtual classroom environment: a feasibility study ]]> https://biorxiv.org/content/10.1101/2023.08.02.551583v1?rss=1 Guedj, C. Tyrand, R. Badier, E. Planchamp, L. Stringer, M. Zimmermann, M. O. Ferat, V. Ha-Vinh Leuchter, R. Grouiller, F. 2023-08-05 doi:10.1101/2023.08.02.551583 Cold Spring Harbor Laboratory Press 2023-08-05 <![CDATA[ SCD inhibition eradicates AML displaying high de novo fatty acid desaturation and synergizes with chemotherapy ]]> https://biorxiv.org/content/10.1101/2023.08.02.551656v1?rss=1 Dembitz, V. Lawson, H. Burt, R. Philippe, C. James, S. C. Atkinson, S. Durko, J. Wang, L. M. Campos, J. Magee, A. M. Woodley, K. Austin, M. J. Rio-Machin, A. Casado-Izquierdo, P. Bewicke-Copley, F. Rodriguez, G. Pereira, D. Oudejans, L. Boet, E. von Kriegsheim, A. Schwaller, J. Finch, A. J. Pate, B. Sarry, J.-E. Tamburini, J. Schuringa, J. J. Hazlehurst, L. Copland, J. A. Yuneva, M. Peck, B. Cutillas, P. Fitzgibbon, J. Rouault-Pierre, K. Kranc, K. Gallipoli, P. 2023-08-05 doi:10.1101/2023.08.02.551656 Cold Spring Harbor Laboratory Press 2023-08-05 <![CDATA[ The circadian clock is a pacemaker of the axonal regenerative ability ]]> https://biorxiv.org/content/10.1101/2023.08.07.552230v1?rss=1 De Virgiliis, F. Mueller, F. Palmisano, I. Chadwick, J. S. Luengo Gutierrez, L. Giarrizzo, A. Yan, Y. Danzi, M. C. Picon Munoz, C. Zhou, L. Kong, G. Serger, E. Hutson, T. H. Scheiermann, C. Brancaccio, M. Di Giovanni, S. 2023-08-07 doi:10.1101/2023.08.07.552230 Cold Spring Harbor Laboratory Press 2023-08-07 <![CDATA[ Benchmarking combined informatics approaches for virus discovery: Caution is needed when combining in silico identification methods ]]> https://biorxiv.org/content/10.1101/2023.08.07.552334v1?rss=1 Hegarty, B. Riddell, J. Bastien, G. E. Langenfeld, K. Lindback, M. Saini, J. S. Wing, A. Zhang, J. Duhaime, M. 2023-08-08 doi:10.1101/2023.08.07.552334 Cold Spring Harbor Laboratory Press 2023-08-08 <![CDATA[ Single-cell transcriptome landscape of developing fetal gonads defines somatic cell lineage specification in humans ]]> https://biorxiv.org/content/10.1101/2023.08.07.552336v1?rss=1 Lardenois, A. Suglia, A. Moore, C. L. Evrard, B. Noel, L. Rivaud, P. Besson, A. Toupin, M. Leonard, S. Lesne, L. Coiffec, I. Nef, s. Lavoue, V. Collin, O. Chedotal, A. Mazaud-Guittot, S. Chalmel, F. Rolland, A. D. 2023-08-08 doi:10.1101/2023.08.07.552336 Cold Spring Harbor Laboratory Press 2023-08-08 <![CDATA[ Expansion of a frontostriatal salience network in individuals with depression ]]> https://biorxiv.org/content/10.1101/2023.08.09.551651v1?rss=1 21,000 minutes of fMRI data, we show that the frontostriatal salience network is expanded two-fold in most individuals with depression. This effect was replicable in multiple samples, including large-scale, group-average data (N=1,231 subjects), and caused primarily by network border shifts affecting specific functional systems, with three distinct modes of encroachment occurring in different individuals. Salience network expansion was unexpectedly stable over time, unaffected by changes in mood state, and detectable in children before the subsequent onset of depressive symptoms in adolescence. Longitudinal analyses of individuals scanned up to 62 times over 1.5 years identified connectivity changes in specific frontostriatal circuits that tracked fluctuations in specific symptom domains and predicted future anhedonia symptoms before they emerged. Together, these findings identify a stable trait-like brain network topology that may confer risk for depression and mood-state dependent connectivity changes in frontostriatal circuits that predict the emergence and remission of depressive symptoms over time. ]]> Lynch, C. J. Elbau, I. Ng, T. Ayaz, A. Zhu, S. Manfredi, N. Johnson, M. Wolk, D. Power, J. D. Gordon, E. M. Kay, K. Aloysi, A. Moia, S. Gaudes, C. C. Victoria, L. W. Solomonov, N. Goldwaser, E. Zebley, B. Grosenick, L. Downar, J. Vila-Rodriguez, F. Daskalakis, Z. J. Blumberger, D. M. Williams, N. Gunning, F. Liston, C. 2023-08-14 doi:10.1101/2023.08.09.551651 Cold Spring Harbor Laboratory Press 2023-08-14 <![CDATA[ Dendritic cell-mediated responses to secreted Cryptosporidium effectors are required for parasite-specific CD8+ T cell responses ]]> https://biorxiv.org/content/10.1101/2023.08.16.553566v1?rss=1 Haskins, B. E. Gullicksrud, J. A. Wallbank, B. A. Dumaine, J. E. Guerin, A. Cohn, I. S. O'Dea, K. M. Pardy, R. D. Merolle, M. I. Shallberg, L. A. Hunter, E. N. Byerly, J. H. Smith, E. J. Buenconsejo, G. Y. McLeod, B. I. Christian, D. A. Striepen, B. Hunter, C. A. 2023-08-18 doi:10.1101/2023.08.16.553566 Cold Spring Harbor Laboratory Press 2023-08-18 <![CDATA[ UBAP2L drives scaffold assembly of nuclear pore complexes at the intact nuclear envelope ]]> https://biorxiv.org/content/10.1101/2023.08.21.554160v1?rss=1 LIAO, Y. Andronov, L. Liu, X. Lin, J. Guerber, L. Lu, L. Agote-Aran, A. Pangou, E. Ran, L. Kleiss, C. Qu, M. Schmucker, S. Cirillo, L. ZHANG, Z. Riveline, D. Gotta, M. Klaholz, B. Sumara, I. 2023-08-21 doi:10.1101/2023.08.21.554160 Cold Spring Harbor Laboratory Press 2023-08-21 <![CDATA[ Regional Differences in Progenitor Consumption Dynamics Shape Brain Growth during Development ]]> https://biorxiv.org/content/10.1101/2023.08.21.553891v1?rss=1 Baumann, N. Wagener, R. Javed, A. Abe, P. Lopes, A. Lavalley, A. Fuciec, D. Magrinelli, E. Fievre, S. Jabaudon, D. 2023-08-22 doi:10.1101/2023.08.21.553891 Cold Spring Harbor Laboratory Press 2023-08-22 <![CDATA[ CryoEM architecture of a native stretch-sensitive membrane microdomain ]]> https://biorxiv.org/content/10.1101/2023.08.25.554800v1?rss=1 Kefauver, J. M. Hakala, M. Zou, L. Alba, J. Espadas Moreno, J. Tettamanti, M. G. Estrozi, L. F. Vanni, S. Roux, A. Desfosses, A. Loewith, R. 2023-08-26 doi:10.1101/2023.08.25.554800 Cold Spring Harbor Laboratory Press 2023-08-26 <![CDATA[ Cis-regulatory polymorphism at fiz ecdysone oxidase contributes to polygenic adaptation to malnutrition in Drosophila ]]> https://biorxiv.org/content/10.1101/2023.08.28.555138v1?rss=1 250 generations of experimental evolution to a nutritionally poor larval diet (Selected populations) evolved several-fold lower fiz expression compared to unselected Control populations. This divergence in fiz expression is mediated by a cis-regulatory polymorphism. This polymorphism, which was originally present in a sample from a natural population in Switzerland, is distinct from a second cis-regulatory SNP previously identified in non-African D. melanogaster populations, implying that two independent cis-regulatory variants promoting high fiz expression segregate in non-African populations. Enzymatic analyses of Fiz protein expressed in E. coli demonstrate that it has ecdysone oxidase activity acting on both ecdysone and 20-hydroxyecdysone. Four of five fiz paralogs annotated to ecdysteroid metabolism also show reduced expression in Selected larvae, suggesting that malnutrition-driven selection favored general downregulation of ecdysone oxidases. Finally, as an independent test of the role of fiz in poor diet adaptation, we show that fiz knockdown by RNAi results in faster larval growth on the poor diet, but at the cost of greatly reduced survival. These results imply that downregulation of fiz in Selected populations was favored because of its role in suppressing growth in response to nutrient shortage. However, fiz downregulation is only adaptive in combination with other changes evolved by Selected populations, such as in nutrient acquisition and metabolism, which ensure that the organism can actually sustain the faster growth promoted by fiz downregulation. ]]> Cavigliasso, F. Savitskiy, M. Koval, A. Erkosar, B. Savary, L. Gallart-Ayala, H. Ivanisevic, J. Katanaev, V. L. Kawecki, T. J. 2023-08-29 doi:10.1101/2023.08.28.555138 Cold Spring Harbor Laboratory Press 2023-08-29 <![CDATA[ Exploring "dark matter" protein folds using deep learning ]]> https://biorxiv.org/content/10.1101/2023.08.30.555621v1?rss=1 Harteveld, Z. Van Hall-Beauvais, A. Morozova, I. Southern, J. Goverde, C. A. Georgeon, S. Rosset, S. Loukas, A. Vandergheynst, P. Bronstein, M. Correia, B. 2023-09-01 doi:10.1101/2023.08.30.555621 Cold Spring Harbor Laboratory Press 2023-09-01 <![CDATA[ New structural features of the APC/C revealed by high resolution cryo-EM structures of apo-APC/C and the APC/C CDH1:EMI1 complex ]]> https://biorxiv.org/content/10.1101/2023.08.31.555674v1?rss=1 Hoefler, A. Yu, J. Yang, J. Zhang, Z. Chang, L. Grime, G. W. Garman, E. F. Boland, A. Barford, D. 2023-09-01 doi:10.1101/2023.08.31.555674 Cold Spring Harbor Laboratory Press 2023-09-01 <![CDATA[ Social Context and Drug Cues Modulate Inhibitory Control in Cocaine Addiction: involvement of the STN evidenced through Functional Magnetic Resonance Imaging ]]> https://biorxiv.org/content/10.1101/2023.09.06.556336v1?rss=1 Terenzi, D. Simon, N. Gachomba, M. J. M. de Peretti, J. L. Nazarian, B. Sein, J. Anton, J.-L. Grandjean, D. Baunez, C. Chaminade, T. 2023-09-06 doi:10.1101/2023.09.06.556336 Cold Spring Harbor Laboratory Press 2023-09-06 <![CDATA[ Deep learning-assisted single-molecule detection of protein post-translational modifications with a biological nanopore ]]> https://biorxiv.org/content/10.1101/2023.09.08.555904v1?rss=1 Cao, C. Magalhaes, P. Krapp, L. Bada Juarez, J. Mayer, S. Rukes, V. Chiki, A. Lashuel, H. Dal Peraro, M. 2023-09-08 doi:10.1101/2023.09.08.555904 Cold Spring Harbor Laboratory Press 2023-09-08 <![CDATA[ High-throughput in vivo synaptic connectivity mapping of neuronal micro-circuits using two-photon holographic optogenetics and compressive sensing ]]> https://biorxiv.org/content/10.1101/2023.09.11.557026v1?rss=1 Chen, I.-W. Chan, C. Y. Navarro, P. de Sars, V. Ronzitti, E. Oweiss, K. Tanese, D. Emiliani, V. 2023-09-13 doi:10.1101/2023.09.11.557026 Cold Spring Harbor Laboratory Press 2023-09-13 <![CDATA[ Learning to operate an imagined speech Brain-Computer Interface involves the spatial and frequency tuning of neural activity ]]> https://biorxiv.org/content/10.1101/2023.09.11.557181v1?rss=1 Bhadra, K. Giraud, A.-L. Marchesotti, S. 2023-09-13 doi:10.1101/2023.09.11.557181 Cold Spring Harbor Laboratory Press 2023-09-13 <![CDATA[ Dual lineage origins of neocortical astrocytes ]]> https://biorxiv.org/content/10.1101/2023.09.12.557313v1?rss=1 Zhou, J. Vitali, I. Roig Puiggros, S. Javed, A. Jabaudon, D. Mayer, C. Bocchi, R. 2023-09-13 doi:10.1101/2023.09.12.557313 Cold Spring Harbor Laboratory Press 2023-09-13 <![CDATA[ Involvement of remote regions in sustained, but not transient, epileptic activities in the kainate mouse model of temporal lobe epilepsy ]]> https://biorxiv.org/content/10.1101/2023.09.14.557684v1?rss=1 Padmasola, G. P. Friscourt, F. Schaller, K. Michel, C. M. Sheybani, L. Quairiaux, C. 2023-09-14 doi:10.1101/2023.09.14.557684 Cold Spring Harbor Laboratory Press 2023-09-14 <![CDATA[ Sclerostin blockade inhibits bone resorption through PDGF receptor signaling in osteoblast lineage cells ]]> https://biorxiv.org/content/10.1101/2023.09.11.557168v1?rss=1 Thouverey, C. Apostolides, P. Brun, J. Caverzasio, J. Ferrari, S. 2023-09-15 doi:10.1101/2023.09.11.557168 Cold Spring Harbor Laboratory Press 2023-09-15 <![CDATA[ Centrosome age breaks spindle size symmetry even in symmetrically dividing cells ]]> https://biorxiv.org/content/10.1101/2023.09.15.557935v1?rss=1 Thomas, A. Meraldi, P. 2023-09-15 doi:10.1101/2023.09.15.557935 Cold Spring Harbor Laboratory Press 2023-09-15 <![CDATA[ Entering new circles: Expansion of the LC8/DYNLL1 interactome in the ciliary-centrosomal network through system-driven motif evolution ]]> https://biorxiv.org/content/10.1101/2023.09.15.557927v1?rss=1 Pajkos, M. Szaniszlo, T. Fulop, M. Dosztanyi, Z. 2023-09-16 doi:10.1101/2023.09.15.557927 Cold Spring Harbor Laboratory Press 2023-09-16 <![CDATA[ Mechanism for Vipp1 spiral formation, ring biogenesis and membrane repair ]]> https://biorxiv.org/content/10.1101/2023.09.26.559607v1?rss=1 Naskar, S. Merino, A. Espadas, J. Singh, J. Roux, A. Colom, A. Low, H. H. 2023-09-26 doi:10.1101/2023.09.26.559607 Cold Spring Harbor Laboratory Press 2023-09-26 <![CDATA[ Emergence of a somatosensory tonotopic map for substrate vibration in the brainstem ]]> https://biorxiv.org/content/10.1101/2023.09.26.559502v1?rss=1 Lee, K.-S. de Thomas Wagner, D. Sanders, M. Huber, D. 2023-09-27 doi:10.1101/2023.09.26.559502 Cold Spring Harbor Laboratory Press 2023-09-27 <![CDATA[ A SUMO E3 ligase promotes long non-coding RNA transcription to regulate small RNA-directed DNA elimination ]]> https://biorxiv.org/content/10.1101/2023.09.27.558415v1?rss=1 Shehzada, S. Noto, T. Saksouk, J. Mochizuki, K. 2023-09-27 doi:10.1101/2023.09.27.558415 Cold Spring Harbor Laboratory Press 2023-09-27 <![CDATA[ Development of novel genetically-encoded fluorescent probes to track ceramides during phagocytosis ]]> https://biorxiv.org/content/10.1101/2023.09.27.559623v1?rss=1 Girik, V. Van Ek, L. Dentand Quadri, I. Azam, M. Cruz Cobo, M. Mandavit, M. Riezman, I. Riezman, H. Gavin, A.-C. Nunes-Hasler, P. 2023-09-27 doi:10.1101/2023.09.27.559623 Cold Spring Harbor Laboratory Press 2023-09-27 <![CDATA[ Comparative Analysis of SARS-CoV-2 Antigenicity across Assays and in Human and Animal Model Sera ]]> https://biorxiv.org/content/10.1101/2023.09.27.559689v1?rss=1 Mühlemann, B. Wilks, S. H. Baracco, L. Bekliz, M. Carreno, J. M. Corman, V. M. Davis-Gardner, M. E. Dejnirattisai, W. Diamond, M. Doueck, D. Drosten, C. Eckerle, I. Edara, V. V. Ellis, M. Fouchier, R. A. Frieman, M. Godbole, S. Haagmans, B. Halfmann, P. Henry, A. R. Jones, T. C. Katzelnick, L. Kawaoka, Y. Kimpel, J. Krammer, F. Lai, L. Liu, C. Lusvarghi, S. Meyer, B. Mongkolsapaya, J. Montefiori, D. Mykytyn, A. Z. Netzl, A. Pollett, S. Rössler, A. Screaton, G. Shen, X. Sigal, A. Simon, V. Subramanian, R. Supasa, P. Suthar, M. Tureli, S. Wang, W. We 2023-09-27 doi:10.1101/2023.09.27.559689 Cold Spring Harbor Laboratory Press 2023-09-27 <![CDATA[ DeepGO-SE: Protein function prediction as Approximate Semantic Entailment ]]> https://biorxiv.org/content/10.1101/2023.09.26.559473v1?rss=1 Kulmanov, M. Guzman-Vega, F. J. Duek Roggli, P. Lane, L. Arold, S. T. Hoehndorf, R. 2023-09-28 doi:10.1101/2023.09.26.559473 Cold Spring Harbor Laboratory Press 2023-09-28 <![CDATA[ Taxonomy for human social perception ]]> https://biorxiv.org/content/10.1101/2023.09.28.559888v1?rss=1 Santavirta, S. Malen, T. Erdemli, A. Nummenmaa, L. 2023-09-29 doi:10.1101/2023.09.28.559888 Cold Spring Harbor Laboratory Press 2023-09-29 <![CDATA[ Sensorimotor brain-computer interface performance depends on signal-to-noise ratio but not connectivity of the mu rhythm in a multiverse analysis of longitudinal data ]]> https://biorxiv.org/content/10.1101/2023.09.30.558407v1?rss=1 Kapralov, N. Jamshidi Idaji, M. Stephani, T. Studenova, A. Vidaurre, C. Ros, T. Villringer, A. Nikulin, V. 2023-10-02 doi:10.1101/2023.09.30.558407 Cold Spring Harbor Laboratory Press 2023-10-02 <![CDATA[ GLUD1 dictates muscle stem cell differentiation by controlling mitochondrial glutamate levels ]]> https://biorxiv.org/content/10.1101/2023.10.04.560525v1?rss=1 View larger version (49K): org.highwire.dtl.DTLVardef@e3585dorg.highwire.dtl.DTLVardef@1be4a54org.highwire.dtl.DTLVardef@1f077org.highwire.dtl.DTLVardef@15220f1_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIGlutamine is the major TCA cycle substrate in MuSCs with decreasing contribution upon differentiation. C_LIO_LILoss of Glud1 impairs MuSC self-renewal capacity and causes imbalanced fusion in vitro and in vivo. C_LIO_LIGlud1 deletion leads to mitochondrial glutamate trapping and malate-aspartate shuttle (MAS) dysfunction. C_LIO_LIRestoration of MAS activity in Glud1 deficient MuSCs reverses precocious differentiation and imbalanced fusion. C_LI ]]> Soro-Arnaiz, I. Cherkaoui, S. Fitzgerald, G. Zhang, J. Gilardoni, P. Gosh, A. Bar-Nur, O. Masschelein, E. Maechler, P. Zamboni, N. Poms, M. Cremonesi, A. Garcia-Canaveras, J. C. De Bock, K. Morscher, R. J. 2023-10-05 doi:10.1101/2023.10.04.560525 Cold Spring Harbor Laboratory Press 2023-10-05 <![CDATA[ Dynamic intraglomerular neuronal ensembles represent odor identity and concentration ]]> https://biorxiv.org/content/10.1101/2023.10.05.560824v1?rss=1 Loizeau, M. Angelova, A. Cremer, H. Platel, J.-C. 2023-10-06 doi:10.1101/2023.10.05.560824 Cold Spring Harbor Laboratory Press 2023-10-06 <![CDATA[ Fine-tuning FAM161A gene augmentation therapy to restore retinal function ]]> https://biorxiv.org/content/10.1101/2023.10.06.561164v1?rss=1 Arsenijevic, Y. Chang, N. Mercey, O. El Fersioui, Y. Koskiniemi-Kuendig, H. Joubert, C. Bemelmans, A.-P. Rivolta, C. Banin, E. Sharon, D. Guichard, P. Hamel, V. Kostic, C. 2023-10-06 doi:10.1101/2023.10.06.561164 Cold Spring Harbor Laboratory Press 2023-10-06 <![CDATA[ Bsp1, a fungal CPI motif protein, regulates actin filament capping in endocytosis and cytokinesis ]]> https://biorxiv.org/content/10.1101/2023.10.09.561521v1?rss=1 Hummel, D. R. Hakala, M. Toret, C. P. Kaksonen, M. 2023-10-10 doi:10.1101/2023.10.09.561521 Cold Spring Harbor Laboratory Press 2023-10-10 <![CDATA[ Accelerated brain change in healthy adults is associated with genetic risk for Alzheimer's disease and uncovers adult lifespan memory decline ]]> https://biorxiv.org/content/10.1101/2023.10.09.559446v1?rss=1 Roe, J. M. Vidal-Pineiro, D. Sorensen, O. Grydeland, H. Leonardsen, E. H. Iakunchykova, O. Pan, M. Mowinckel, A. Stromstad, M. Nawijn, L. Milaneschi, Y. Andersson, M. Pudas, S. Brathen, A. C. S. Kransberg, J. Falch, E. S. Overbye, K. Kievit, R. A. Ebmeier, K. P. Lindenberger, U. Ghisletta, P. Demnitz, N. Boraxbekk, C.-J. Penninx, B. Bertram, L. Nyberg, L. Walhovd, K. B. Fjell, A. M. Wang, Y. 2023-10-12 doi:10.1101/2023.10.09.559446 Cold Spring Harbor Laboratory Press 2023-10-12 <![CDATA[ Robust estimation of cancer and immune cell-type proportions from bulk tumor ATAC-Seq data. ]]> https://biorxiv.org/content/10.1101/2023.10.11.561826v1?rss=1 Gabriel, A. A. Racle, J. Falquet, M. Jandus, C. Gfeller, D. 2023-10-14 doi:10.1101/2023.10.11.561826 Cold Spring Harbor Laboratory Press 2023-10-14 <![CDATA[ Mechanistic insights into the function of 14-3-3 proteins as negative regulators of brassinosteroid signaling in Arabidopsis. ]]> https://biorxiv.org/content/10.1101/2023.10.13.562204v1?rss=1 Obergfell, E. Hohmann, U. Moretti, A. Hothorn, M. 2023-10-14 doi:10.1101/2023.10.13.562204 Cold Spring Harbor Laboratory Press 2023-10-14 <![CDATA[ Transformation of neural coding for vibrotactile stimuli along the ascending somatosensory pathway ]]> https://biorxiv.org/content/10.1101/2023.10.13.562210v1?rss=1 Lee, K.-S. Loutit, A. de Thomas Wagner, D. Sanders, M. Prsa, M. Huber, D. 2023-10-17 doi:10.1101/2023.10.13.562210 Cold Spring Harbor Laboratory Press 2023-10-17 <![CDATA[ Cortical circuits for goal-directed cross-modal transfer learning ]]> https://biorxiv.org/content/10.1101/2023.10.13.562215v1?rss=1 Guyoton, M. Matteucci, G. Foucher, C. G. El-Boustani, S. 2023-10-17 doi:10.1101/2023.10.13.562215 Cold Spring Harbor Laboratory Press 2023-10-17 <![CDATA[ Dogs' sensory-motor tuning shapes dog-human vocal interactions ]]> https://biorxiv.org/content/10.1101/2023.10.18.562860v1?rss=1 DEAUX, E. Piette, T. Gaunet, F. Legou, T. Arnal, L. Giraud, A.-L. 2023-10-19 doi:10.1101/2023.10.18.562860 Cold Spring Harbor Laboratory Press 2023-10-19 <![CDATA[ Preventing extinction in an age of species migration and planetary change ]]> https://biorxiv.org/content/10.1101/2023.10.17.562809v1?rss=1 Lundgren, E. J. Wallach, A. D. Svenning, J.-C. Schlaepfer, M. Andersson, A. L. A. Ramp, D. 2023-10-20 doi:10.1101/2023.10.17.562809 Cold Spring Harbor Laboratory Press 2023-10-20 <![CDATA[ Diurnal control of iron responsive element (IRE)-containing mRNAs through iron regular proteins IRP1 and IRP2 is mediated by feeding rhythms ]]> https://biorxiv.org/content/10.1101/2023.10.23.563593v1?rss=1 Nadimpalli, H. P. Katsioudi, G. Arpa, E. S. Chikhaoui, L. Arpat, A. B. Liechti, A. Palais, G. Tessmer, C. Hofmann, I. Galy, B. Gatfield, D. 2023-10-23 doi:10.1101/2023.10.23.563593 Cold Spring Harbor Laboratory Press 2023-10-23 <![CDATA[ Optimization of a deep mutational scanning workflow to improve quantification of mutation effects on protein-protein interactions ]]> https://biorxiv.org/content/10.1101/2023.10.23.563542v1?rss=1 Bendel, A. M. Skendo, K. Klein, D. Shimada, K. Kauneckaite-Griguole, K. Diss, G. 2023-10-24 doi:10.1101/2023.10.23.563542 Cold Spring Harbor Laboratory Press 2023-10-24 <![CDATA[ Insights into assembly of constitutive filament-forming proteins of novel fold through domain dissection and EGFP insertion-based screen: A case study of Spiroplasma Fibril ]]> https://biorxiv.org/content/10.1101/2023.10.26.564286v1?rss=1 Bapat, M. Harne, S. R. Kashyap, R. Gayathri, P. 2023-10-27 doi:10.1101/2023.10.26.564286 Cold Spring Harbor Laboratory Press 2023-10-27 <![CDATA[ ProA and ProB repeat sequences shape genome organization, and enhancers open domains ]]> https://biorxiv.org/content/10.1101/2023.10.27.564043v1?rss=1 Bonnet, K. A. Hulo, N. Mourad, R. Ewing, A. Croce, O. Naville, M. Vassetzky, N. Gilson, E. Picard, D. Fourel, G. 2023-10-29 doi:10.1101/2023.10.27.564043 Cold Spring Harbor Laboratory Press 2023-10-29 <![CDATA[ Impairment of hippocampal astrocyte-mediated striatal dopamine release and locomotion in Alzheimer's disease ]]> https://biorxiv.org/content/10.1101/2023.10.29.564619v1?rss=1 Tournier, B. B. Ceyzeriat, K. Badina, A. Gloria, Y. Fall, A. Amosse, Q. Tsartsalis, S. Millet, P. 2023-10-30 doi:10.1101/2023.10.29.564619 Cold Spring Harbor Laboratory Press 2023-10-30 <![CDATA[ Low-dimensional neuronal population dynamics in anterior superior temporal gyrus reactivate phonetic representations during semantic processing ]]> https://biorxiv.org/content/10.1101/2023.10.30.564638v1?rss=1 Orepic, P. Truccolo, W. Cash, S. S. Giraud, A.-L. Proix, T. 2023-10-31 doi:10.1101/2023.10.30.564638 Cold Spring Harbor Laboratory Press 2023-10-31 <![CDATA[ Immunosuppression is a conserved driver of tuberculosis susceptibility ]]> https://biorxiv.org/content/10.1101/2023.10.27.564420v1?rss=1 Kotov, D. I. Lee, O. V. Ji, D. X. Jaye, D. L. Suliman, S. Gabay, C. Vance, R. E. 2023-11-01 doi:10.1101/2023.10.27.564420 Cold Spring Harbor Laboratory Press 2023-11-01 <![CDATA[ Altered astrocytic and microglial homeostasis characterizes a decreased proinflammatory state in bipolar disorder ]]> https://biorxiv.org/content/10.1101/2023.10.29.564621v1?rss=1 Amosse, Q. Tournier, B. B. Badina, A. M. Marchand-Maillet, L. Abjean, L. Lengacher, S. Fancy, N. Smith, A. M. Leung, Y.-Y. Santer, V. Garibotto, V. Owen, D. R. Piguet, C. Ceyzeriat, K. Tsartsalis, S. Millet, P. 2023-11-01 doi:10.1101/2023.10.29.564621 Cold Spring Harbor Laboratory Press 2023-11-01 <![CDATA[ SWISH-X, an expanded approach to detect cryptic pockets inproteins and at protein-protein interfaces ]]> https://biorxiv.org/content/10.1101/2023.11.03.565527v1?rss=1 Borsatto, A. Gianquinto, E. Rizzi, V. Gervasio, F. L. 2023-11-05 doi:10.1101/2023.11.03.565527 Cold Spring Harbor Laboratory Press 2023-11-05 <![CDATA[ Combined blockade of CXCR4 and PD-1 enhances intratumoral dendritic cell activation and immune responses against HCC ]]> https://biorxiv.org/content/10.1101/2023.11.06.564640v1?rss=1 Morita, S. Shigeta, K. Lei, P. Kobayashi, T. Kikuchi, H. Matsui, A. Huang, P. Pittet, M. Duda, D. 2023-11-06 doi:10.1101/2023.11.06.564640 Cold Spring Harbor Laboratory Press 2023-11-06 <![CDATA[ SPATEs promote the survival of Shigella to the plasma complement system upon hemorrhage and bacteremia ]]> https://biorxiv.org/content/10.1101/2023.11.08.565994v1?rss=1 Debande, L. Sabbah, A. Kuhn, L. Ngondo, P. Andre, A. C. Roche, B. Laborde, M. Cantalapiedra-Mateo, M.-V. Thahouly, T. Milinski, A. Bianchetti, L. Allmang-Cura, C. Frugier, M. Marteyn, B. S. 2023-11-08 doi:10.1101/2023.11.08.565994 Cold Spring Harbor Laboratory Press 2023-11-08 <![CDATA[ BioWiC: An Evaluation Benchmark for Biomedical Concept Representation ]]> https://biorxiv.org/content/10.1101/2023.11.08.566170v1?rss=1 Rouhizadeh, H. Nikishina, I. Yazdani, A. Bornet, A. Zhang, B. Ehrsam, J. Gaudet-Blavignac, C. Naderi, N. Teodoro, D. 2023-11-11 doi:10.1101/2023.11.08.566170 Cold Spring Harbor Laboratory Press 2023-11-11 <![CDATA[ Development of supramolecular anticoagulants with on-demand reversibility ]]> https://biorxiv.org/content/10.1101/2023.11.12.566735v1?rss=1 Dockerill, M. Ford, D. J. Angerani, S. Alwis, I. Ripoll-Rozada, J. Smythe, R. E. Liu, J. S. T. Barbosa Pereira, P. J. Jackson, S. P. Payne, R. J. Winssinger, N. 2023-11-12 doi:10.1101/2023.11.12.566735 Cold Spring Harbor Laboratory Press 2023-11-12 <![CDATA[ Multi-timescale reinforcement learning in the brain ]]> https://biorxiv.org/content/10.1101/2023.11.12.566754v1?rss=1 Masset, P. Tano, P. Kim, H. R. Malik, A. N. Pouget, A. Uchida, N. 2023-11-14 doi:10.1101/2023.11.12.566754 Cold Spring Harbor Laboratory Press 2023-11-14 <![CDATA[ A single-cell atlas of E. faecalis wound infection reveals novel bacterial-host immunomodulatory mechanisms ]]> https://biorxiv.org/content/10.1101/2023.11.16.566967v1?rss=1 Celik, C. Lee, S. Y. T. Reinhart Tonoto, F. Veleba, M. Kline, K. A. Thibault, G. A. 2023-11-16 doi:10.1101/2023.11.16.566967 Cold Spring Harbor Laboratory Press 2023-11-16 <![CDATA[ The HtrA chaperone monitors sortase-assembled pilus biogenesis in Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2023.11.20.567783v1?rss=1 Yong, A. M. H. Colomer Winter, C. Chong, K. K. L. Gao, I. H. Matysik, A. Chen, S. L. Kline, K. A. 2023-11-20 doi:10.1101/2023.11.20.567783 Cold Spring Harbor Laboratory Press 2023-11-20 <![CDATA[ Applying Super-Resolution and Tomography Concepts to Identify Receptive Field Subunits in the Retina ]]> https://biorxiv.org/content/10.1101/2023.11.27.568854v1?rss=1 Krueppel, S. Khani, M. H. Schreyer, H. M. Sridhar, S. Ramakrishna, V. Zapp, S. J. Mietsch, M. Karamanlis, D. Gollisch, T. 2023-11-27 doi:10.1101/2023.11.27.568854 Cold Spring Harbor Laboratory Press 2023-11-27 <![CDATA[ Decoupling Dopamine Synthesis from Impulsive Action, Risk-related Decision-Making, and Propensity to Cocaine Intake: A Longitudinal -FDOPA PET Study in Roman High- and Low-avoidance Rats ]]> https://biorxiv.org/content/10.1101/2023.11.29.569200v1?rss=1 Uruena-Mendez, G. Arrondeau, C. Belles, L. Ginovart, N. 2023-11-30 doi:10.1101/2023.11.29.569200 Cold Spring Harbor Laboratory Press 2023-11-30 <![CDATA[ Interconversion of tripartite and bipartite systems for site-specific O-sialylation of flagellin in Gram-negative and Gram-positive bacteria ]]> https://biorxiv.org/content/10.1101/2023.12.03.569772v1?rss=1 Unay, J. Kint, N. Viollier, P. H. 2023-12-03 doi:10.1101/2023.12.03.569772 Cold Spring Harbor Laboratory Press 2023-12-03 <![CDATA[ Continuous estimation of reaching space in superficial layers of the motor cortex ]]> https://biorxiv.org/content/10.1101/2023.12.01.569527v1?rss=1 80%) of L2/3 neurons with task-related activity are target-space selective and their activity is contingent on a single target position in an ego-centric reference frame. This spatial framework is preferentially organized along three cardinal directions (Center, Left and Right). Surprisingly, the coding of target space is not limited to the activity during movement planning or execution, but is also predominant during preceding and subsequent phases of the task, and even persists beyond water consumption. More importantly, target specificity is independent of the movement kinematics and is immediately updated when the target is moved to a new position. Our findings suggest that, rather than descending motor commands, the ensemble of L2/3 neurons in the motor cortex conjointly encode internal (behavioral) and external (spatial) aspects of the task, playing a role in higher-order representations related to estimation processes of the ongoing actions. ]]> Galinanes, G. L. Huber, D. 2023-12-04 doi:10.1101/2023.12.01.569527 Cold Spring Harbor Laboratory Press 2023-12-04 <![CDATA[ Membrane specificity of the human cholesterol transfer protein STARD4 ]]> https://biorxiv.org/content/10.1101/2023.12.04.569895v1?rss=1 Talandashti, R. van Ek, L. Gehin, C. Xue, D. Moqadam, M. Gavin, A.-C. Reuter, N. 2023-12-04 doi:10.1101/2023.12.04.569895 Cold Spring Harbor Laboratory Press 2023-12-04 <![CDATA[ Reprogramming neuroblastoma by diet-enhanced polyamine depletion ]]> https://biorxiv.org/content/10.1101/2024.01.07.573662v1?rss=1 View larger version (64K): org.highwire.dtl.DTLVardef@1fdbaecorg.highwire.dtl.DTLVardef@fb03f4org.highwire.dtl.DTLVardef@1c0afa7org.highwire.dtl.DTLVardef@14c384f_HPS_FORMAT_FIGEXP M_FIG C_FIG Highlights- Extra-tumoral conversion of arginine feeds tumor ornithine via uptake from circulation in MYCN-neuroblastoma. - A proline and arginine free diet enhances pharmacological polyamine depletion via reduced ornithine substrate availability. - Polyamine depletion disrupts oncogenic translation to induce a pro-differentiation proteome causing neuroblast differentiation and prolonged survival in the TH-MYCN mouse model. - Genes of specific cellular programs have evolved codon usage preferences that enable coherent translational rewiring in response to metabolic stress, such as polyamine depletion. ]]> Cherkaoui, S. Yang, L. McBride, M. J. Turn, C. Lu, W. Eigenmann, C. Allen, G. E. Panasenko, O. O. Zhang, L. Vu, A. Liu, K. Li, Y. Gandhi, O. H. Surrey, L. Wierer, M. White, E. Rabinowitz, J. D. Hogarty, M. D. Morscher, R. J. 2024-01-08 doi:10.1101/2024.01.07.573662 Cold Spring Harbor Laboratory Press 2024-01-08 <![CDATA[ Dissecting the membrane association mechanism of aerolysin pore at femtomolar concentrations using water as a probe ]]> https://biorxiv.org/content/10.1101/2024.01.18.576179v1?rss=1 Roesel, T. Cao, C. Bada Juarez, J. F. Dal Peraro, M. Roke, S. 2024-01-22 doi:10.1101/2024.01.18.576179 Cold Spring Harbor Laboratory Press 2024-01-22 <![CDATA[ Developmental emergence of first- and higher-order thalamic neuron molecular identities ]]> https://biorxiv.org/content/10.1101/2024.01.22.576610v1?rss=1 Lo Giudice, Q. Wagener, R. J. Abe, P. Frangeul, L. Jabaudon, D. 2024-01-22 doi:10.1101/2024.01.22.576610 Cold Spring Harbor Laboratory Press 2024-01-22 <![CDATA[ YY1 mutations disrupt corticogenesis and cytoarchitecture through a cell-type specific rewiring of cell-autonomous and non-cell-autonomous transcriptional programs ]]> https://biorxiv.org/content/10.1101/2024.02.16.580337v1?rss=1 Pereira, M. F. Finazzi, V. Rizzuti, L. Aprile, D. Aiello, V. Mollica, L. Riva, M. Soriani, C. Dossena, F. Shyti, R. Castaldi, D. Tenderini, E. Carminho-Rodrigues, M. T. Bally, J. F. de Vries, B. B. A. Gabriele, M. Vitriolo, A. Testa, G. 2024-02-16 doi:10.1101/2024.02.16.580337 Cold Spring Harbor Laboratory Press 2024-02-16 <![CDATA[ Liebenberg syndrome severity arises from variations in Pitx1 locus topology and ectopically transcribing cells ]]> https://biorxiv.org/content/10.1101/2024.03.04.582675v1?rss=1 Bompadre, O. Rouco, R. Darbellay, F. Rauseo, A. Guerard-Millet, F. Gentile, C. Kmita, M. Andrey, G. 2024-03-06 doi:10.1101/2024.03.04.582675 Cold Spring Harbor Laboratory Press 2024-03-06 <![CDATA[ Modeling spatial contrast sensitivity in responses of primate retinal ganglion cells to natural movies ]]> https://biorxiv.org/content/10.1101/2024.03.05.583449v1?rss=1 Sridhar, S. Vystrcilova, M. Khani, M. H. Karamanlis, D. Schreyer, H. M. Ramakrishna, V. Krueppel, S. Zapp, S. J. Mietsch, M. Ecker, A. Gollisch, T. 2024-03-10 doi:10.1101/2024.03.05.583449 Cold Spring Harbor Laboratory Press 2024-03-10 <![CDATA[ Differentiating specific and non-specific protein-metabolite interactions using gradient open port probe electrospray ionization mass spectrometry ]]> https://biorxiv.org/content/10.1101/2024.03.07.583904v1?rss=1 View larger version (20K): org.highwire.dtl.DTLVardef@e2aad7org.highwire.dtl.DTLVardef@13e287borg.highwire.dtl.DTLVardef@1d3c6c0org.highwire.dtl.DTLVardef@9da2a8_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Tian, X. Hopfgartner, G. 2024-03-09 doi:10.1101/2024.03.07.583904 Cold Spring Harbor Laboratory Press 2024-03-09 <![CDATA[ Activation of the mPFC-NAc pathway reduces motor impulsivity but does not affect risk-related decision-making in innately high-impulsive rats ]]> https://biorxiv.org/content/10.1101/2024.03.08.584121v1?rss=1 Arrondeau, C. Uruena-Mendez, G. Marchessaux, F. Goutaudier, R. Ginovart, N. 2024-03-13 doi:10.1101/2024.03.08.584121 Cold Spring Harbor Laboratory Press 2024-03-13 <![CDATA[ Interplay of actin nematodynamics and anisotropic tension controls endothelial mechanics ]]> https://biorxiv.org/content/10.1101/2024.03.10.584287v1?rss=1 Dessalles, C. A. Cuny, N. Boutillon, A. Salipante, P. F. Babataheri, A. Barakat, A. I. Salbreux, G. 2024-03-12 doi:10.1101/2024.03.10.584287 Cold Spring Harbor Laboratory Press 2024-03-12 <![CDATA[ The Dsc ubiquitin ligase complex identifies transmembrane degrons to degrade orphaned proteins at the Golgi ]]> https://biorxiv.org/content/10.1101/2024.03.11.584465v1?rss=1 Weyer, Y. Schwabl, S. I. Tang, X. Widerin, M. A. Niedrist, V. Tettamanti, M. G. Weys, S. Sarg, B. Kremser, L. Liedl, K. R. Schmidt, O. Teis, D. 2024-03-12 doi:10.1101/2024.03.11.584465 Cold Spring Harbor Laboratory Press 2024-03-12 <![CDATA[ Dissociable Roles of the mPFC-to-VTA Pathway in the Control of Impulsive Action and Risk-Related Decision-Making in Roman High- and Low-Avoidance Rats. ]]> https://biorxiv.org/content/10.1101/2024.03.13.584562v1?rss=1 Uruena-Mendez, G. Arrondeau, C. Marchessaux, F. Goutaudier, R. Ginovart, N. 2024-03-14 doi:10.1101/2024.03.13.584562 Cold Spring Harbor Laboratory Press 2024-03-14 <![CDATA[ Neurodevelopmentally rooted epicenters in schizophrenia: sensorimotor-association spatial axis of cortical thickness alterations ]]> https://biorxiv.org/content/10.1101/2024.03.13.584752v1?rss=1 Fan, Y.-S. Xu, Y. Hettwer, M. D. Yang, P. Sheng, W. Wang, C. Yang, M. Kirschner, M. Valk, S. L. Chen, H. 2024-03-18 doi:10.1101/2024.03.13.584752 Cold Spring Harbor Laboratory Press 2024-03-18 <![CDATA[ A deep profile of gene expression across 18 human cancers ]]> https://biorxiv.org/content/10.1101/2024.03.17.585426v1?rss=1 Qiu, W. Dincer, A. B. Janizek, J. Celik, S. Pittet, M. Naxerova, K. Lee, S.-I. 2024-03-17 doi:10.1101/2024.03.17.585426 Cold Spring Harbor Laboratory Press 2024-03-17 <![CDATA[ Trace Amines are Essential Metabolites for the Autocrine Regulation of β-Cell Signaling and Insulin Secretion ]]> https://biorxiv.org/content/10.1101/2024.03.21.585773v1?rss=1 Keutler, K. Hauke, S. Laguerre, A. Andreu-Carbo, M. Rada, J. Grandy, D. Yushchenko, D. A. Schultz, C. 2024-03-23 doi:10.1101/2024.03.21.585773 Cold Spring Harbor Laboratory Press 2024-03-23 <![CDATA[ Temporal constraints on enhancer usage shape the regulation of limb gene transcription ]]> https://biorxiv.org/content/10.1101/2024.03.22.585864v1?rss=1 Rouco, R. Rauseo, A. Sapin, G. Bompadre, O. Darbellay, F. Andrey, G. 2024-03-27 doi:10.1101/2024.03.22.585864 Cold Spring Harbor Laboratory Press 2024-03-27 <![CDATA[ EVOLUTIONARY CO-OPTION OF AN ANCESTRAL CLOACAL REGULATORY LANDSCAPE DURING THE EMERGENCE OF DIGITS AND GENITALS ]]> https://biorxiv.org/content/10.1101/2024.03.24.586442v1?rss=1 Hintermann, A. Bolt, C. C. Hawkins, M. B. Valentin, G. Lopez-Delisle, L. Gitto, S. Gomez, P. B. Mascrez, B. Mansour, T. A. Nakamura, T. Harris, M. P. Shubin, N. H. Duboule, D. 2024-03-27 doi:10.1101/2024.03.24.586442 Cold Spring Harbor Laboratory Press 2024-03-27 <![CDATA[ Nonadjacent Dependencies and Syntactic Structure of Chimpanzee Action During a Natural Tool-Use Task ]]> https://biorxiv.org/content/10.1101/2024.03.25.586385v1?rss=1 Howard-Spink, E. Hayashi, M. Matsuzawa, T. Schofield, D. Gruber, T. Biro, D. 2024-03-29 doi:10.1101/2024.03.25.586385 Cold Spring Harbor Laboratory Press 2024-03-29 <![CDATA[ Arp2/3-dependent actin assembly shapes endosomes and promotes intracellular trafficking in fission yeast ]]> https://biorxiv.org/content/10.1101/2024.03.28.587130v1?rss=1 Melero, A. Muriel-Lopez, O. Basante-Bedoya, M. Martin, S. G. 2024-03-29 doi:10.1101/2024.03.28.587130 Cold Spring Harbor Laboratory Press 2024-03-29 <![CDATA[ Use of Protein interactions from Imaging Complexes after Translocation (PICT) to characterise in situ the spatial configuration of proteins interacting with the exocyst ]]> https://biorxiv.org/content/10.1101/2024.03.28.587178v1?rss=1 Chinchilla Hernandez, A. Betancur Ocampo, L. I. Picco, A. Gallego, O. 2024-03-30 doi:10.1101/2024.03.28.587178 Cold Spring Harbor Laboratory Press 2024-03-30 <![CDATA[ An evolutionary cell biology perspective into the diverging mechanisms of clathrin-mediated endocytosis in dikarya fungi ]]> https://biorxiv.org/content/10.1101/2024.03.28.587219v1?rss=1 Picco, A. Toret, C. P. Rivier-Cordey, A.-S. Kaksonen, M. 2024-03-29 doi:10.1101/2024.03.28.587219 Cold Spring Harbor Laboratory Press 2024-03-29 <![CDATA[ Regulatory Functional Landscape of the HMX1 Gene for Normal Ear Development ]]> https://biorxiv.org/content/10.1101/2024.04.01.587639v1?rss=1 Xu, X. Chen, Q. Huang, Q. Cox, T. C. Zhu, H. Hu, J. Han, X. Meng, Z. Wang, B. Liao, Z. Xu, W. Xiao, B. Lang, R. Liu, J. Li, Q. Zhang, Q. Antonarakis, S. E. Zhang, J. Fan, X. Liu, H. Zhang, Y.-B. 2024-04-02 doi:10.1101/2024.04.01.587639 Cold Spring Harbor Laboratory Press 2024-04-02 <![CDATA[ mTORC1-dependent SOCE activity regulates synaptic gene expression and muscle response to denervation ]]> https://biorxiv.org/content/10.1101/2024.04.01.587665v1?rss=1 Prola, A. Dupont, O. Rajendran, J. Chabry, F. Koenig, S. Frieden, M. Castets, P. 2024-04-02 doi:10.1101/2024.04.01.587665 Cold Spring Harbor Laboratory Press 2024-04-02 <![CDATA[ A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function ]]> https://biorxiv.org/content/10.1101/2024.04.02.587836v1?rss=1 Ganga, A. K. Sweeney, L. K. Rubio-Ramos, A. Bishop, C. S. Hamel, V. Guichard, P. Breslow, D. K. 2024-04-03 doi:10.1101/2024.04.02.587836 Cold Spring Harbor Laboratory Press 2024-04-03 <![CDATA[ Exploring new nanopore sensors from the aerolysin family ]]> https://biorxiv.org/content/10.1101/2024.04.07.588449v1?rss=1 Cirauqui Diaz, N. Bada Juarez, J. F. Meireles, F. A. Barry, J. Bokori-Brown, M. Marcaida, M. J. Cao, C. Dal Peraro, M. 2024-04-10 doi:10.1101/2024.04.07.588449 Cold Spring Harbor Laboratory Press 2024-04-10 <![CDATA[ Topology changes of the regenerating Hydra define actin nematic defects as mechanical organizers of morphogenesis. ]]> https://biorxiv.org/content/10.1101/2024.04.07.588499v1?rss=1 Ravichandran, Y. Vogg, M. Kruse, K. Pearce, D. Roux, A. 2024-04-08 doi:10.1101/2024.04.07.588499 Cold Spring Harbor Laboratory Press 2024-04-08 <![CDATA[ Glutamylation imbalance leads to photoreceptor degeneration ]]> https://biorxiv.org/content/10.1101/2024.04.09.588666v1?rss=1 Mercey, O. Gadadhar, S. Magiera, M. M. Lebrun, L. Kostic, C. Moulin, A. Arsenijevic, Y. Janke, C. Guichard, P. Hamel, V. 2024-04-13 doi:10.1101/2024.04.09.588666 Cold Spring Harbor Laboratory Press 2024-04-13 <![CDATA[ Cerebro-spinal somatotopic organization uncoveredthrough functional connectivity mapping ]]> https://biorxiv.org/content/10.1101/2024.04.11.588866v1?rss=1 Landelle, C. Kinany, N. De Leener, B. Murphy, N. D. Lungu, O. Marchand-Pauvert, V. Van De Ville, D. Doyon, J. 2024-04-12 doi:10.1101/2024.04.11.588866 Cold Spring Harbor Laboratory Press 2024-04-12 <![CDATA[ Soluble αβ-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay ]]> https://biorxiv.org/content/10.1101/2024.04.12.589224v1?rss=1 Batiuk, A. Höpfler, M. Almeida, A. C. En-Jie, D. T. Vadas, O. Vartholomaiou, E. Hegde, R. S. Lin, Z. Gasic, I. 2024-04-13 doi:10.1101/2024.04.12.589224 Cold Spring Harbor Laboratory Press 2024-04-13 <![CDATA[ Refined mechanism of promoter Nucleosome-Depleted Regions resetting after replication ]]> https://biorxiv.org/content/10.1101/2024.04.14.589417v1?rss=1 Zencir, S. Gill, J. K. Stutz, F. Soudet, J. 2024-04-14 doi:10.1101/2024.04.14.589417 Cold Spring Harbor Laboratory Press 2024-04-14 <![CDATA[ Genomic signature of reproductive isolation between the last two remnant populations of Torrey pine (Pinus torreyana Parry) ]]> https://biorxiv.org/content/10.1101/2024.04.15.589509v1?rss=1 Di Santo, L. N. Mead, A. Wright, J. Hamilton, J. 2024-04-16 doi:10.1101/2024.04.15.589509 Cold Spring Harbor Laboratory Press 2024-04-16 <![CDATA[ Efficient fine-tuning of endothelial gene expression by Y to Phe mutation in the VE-cadherin gene ]]> https://biorxiv.org/content/10.1101/2024.04.17.589974v1?rss=1 GARNIER, O. JEANNERET, F. DURAND, A. FERTIN, A. Battail, C. BERNDT, S. CARPENTIER, G. Martin, D. VILGRAIN, I. 2024-04-22 doi:10.1101/2024.04.17.589974 Cold Spring Harbor Laboratory Press 2024-04-22 <![CDATA[ Discovery of anti-infective compounds against Mycobacterium marinum after biotransformation of simple natural stilbene scaffolds by a fungal secretome ]]> https://biorxiv.org/content/10.1101/2024.04.18.590143v1?rss=1 Hanna, N. Soldati, T. Nitschke, J. Huber, R. Vossio, S. Moreau, D. Marcourt, L. Gindro, K. Queiroz, E. F. 2024-04-22 doi:10.1101/2024.04.18.590143 Cold Spring Harbor Laboratory Press 2024-04-22 <![CDATA[ Atypical Audio-Visual Neural Synchrony and Speech Processing in children with Autism Spectrum Disorder ]]> https://biorxiv.org/content/10.1101/2024.04.19.590044v1?rss=1 Wang, X. Bouton, S. Kojovic, N. Giraud, A.-L. Schaer, M. 2024-04-19 doi:10.1101/2024.04.19.590044 Cold Spring Harbor Laboratory Press 2024-04-19 <![CDATA[ Long-term fasting remodels gut microbial metabolism and host metabolism ]]> https://biorxiv.org/content/10.1101/2024.04.19.590209v1?rss=1 Ducarmon, Q. R. Grundler, F. Giannopoulou, C. Loume, A. Karcher, N. Larralde, M. Romano, S. R. MacArthur, M. Mitchell, S. J. Wilhelmi de Toledo, F. Zeller, G. Mesnage, R. 2024-04-19 doi:10.1101/2024.04.19.590209 Cold Spring Harbor Laboratory Press 2024-04-19 <![CDATA[ Accelerated spike-triggered non-negative matrix factorization reveals coordinated ganglion cell subunit mosaics in the primate retina ]]> https://biorxiv.org/content/10.1101/2024.04.22.590506v1?rss=1 Zapp, S. J. Khani, M. H. Schreyer, H. M. Sridhar, S. Ramakrishna, V. Krueppel, S. Mietsch, M. Protti, D. A. Karamanlis, D. Gollisch, T. 2024-04-25 doi:10.1101/2024.04.22.590506 Cold Spring Harbor Laboratory Press 2024-04-25 <![CDATA[ Stm1 regulates Ifh1 activity revealing crosstalk between ribosome biogenesis and ribosome dormancy ]]> https://biorxiv.org/content/10.1101/2024.04.22.590536v1?rss=1 Bianco, E. Bonassera, M. Uliana, F. Tilma, J. Winkler, M. Zencir, S. Albert, B. Oborska-Oplova, M. Dechant, R. Hugener, J. Panse, V. G. Pilhofer, M. Kimmig, P. Peter, M. 2024-04-26 doi:10.1101/2024.04.22.590536 Cold Spring Harbor Laboratory Press 2024-04-26 <![CDATA[ The Wnt/β-catenin/TCF/Sp5/Zic4 gene network that regulates head organizer activity in Hydra is differentially regulated in epidermis and gastrodermis ]]> https://biorxiv.org/content/10.1101/2024.04.27.591423v1?rss=1 Iglesias Olle, L. Perruchoud, C. Sanchez, P. G. L. Vogg, M. C. Galliot, B. 2024-04-29 doi:10.1101/2024.04.27.591423 Cold Spring Harbor Laboratory Press 2024-04-29 <![CDATA[ Inositol pyrophosphate catabolism by three families of phosphatases controls plant growth and development ]]> https://biorxiv.org/content/10.1101/2024.04.30.591831v1?rss=1 Laurent, F. Bartsch, S. M. Shukla, A. Rico Resendiz, F. E. Couto, D. Fuchs, C. Nicolet, J. Loubery, S. Jessen, H. J. Fiedler, D. Hothorn, M. 2024-04-30 doi:10.1101/2024.04.30.591831 Cold Spring Harbor Laboratory Press 2024-04-30 <![CDATA[ Myeloid cell networks determine reinstatement of original immune environments in recurrent ovarian cancer ]]> https://biorxiv.org/content/10.1101/2024.05.02.590528v1?rss=1 Ghisoni, E. Benedetti, F. Minasyan, A. Cunnea, P. Grimm, A. J. Fahr, N. Desbuisson, M. Capt, C. Rayroux, N. Gulhan, D. C. Dagher, J. Barras, D. Morotti, M. Marin Jimenez, J. A. De Carlo, F. Chap, B. S. Spagnol, G. Fleury, M. Fortis, K. Dorier, J. Tissot, S. Rusakiewicz, S. Ferreira, H. J. Bassani-Sternberg, M. Swisher, E. M. Kandalaft, L. Mastroyannis, S. A. Montone, K. T. Powell, D. Pittet, M. J. Tanyi, J. L. Coukos, G. Fotopoulou, C. Conejo-Garcia, J. R. Dangaj Laniti, D. 2024-05-05 doi:10.1101/2024.05.02.590528 Cold Spring Harbor Laboratory Press 2024-05-05 <![CDATA[ Transient lagging chromosomes cause primary microcephaly ]]> https://biorxiv.org/content/10.1101/2024.05.02.592199v1?rss=1 Doria, E. Ivanova, D. Thomas, A. Meraldi, P. 2024-05-02 doi:10.1101/2024.05.02.592199 Cold Spring Harbor Laboratory Press 2024-05-02 <![CDATA[ Accurate single domain scaffolding of three non-overlapping protein epitopes using deep learning ]]> https://biorxiv.org/content/10.1101/2024.05.07.592871v1?rss=1 Castro, K. M. Watson, J. L. Wang, J. Southern, J. Ayardulabi, R. Georgeon, S. Rosset, S. Baker, D. Correia, B. E. 2024-05-10 doi:10.1101/2024.05.07.592871 Cold Spring Harbor Laboratory Press 2024-05-10 <![CDATA[ Compartmental Differences in the Retinal Ganglion Cell Mitochondrial Proteome ]]> https://biorxiv.org/content/10.1101/2024.05.07.593032v1?rss=1 Lewis, L. S. Skiba, N. P. Hao, Y. Bomze, H. M. Arshavsky, V. Y. Cartoni, R. Gospe, S. M. 2024-05-10 doi:10.1101/2024.05.07.593032 Cold Spring Harbor Laboratory Press 2024-05-10 <![CDATA[ A toolbox for genetic targeting of the claustrum ]]> https://biorxiv.org/content/10.1101/2024.05.13.593837v1?rss=1 tuberosa, j. boillat, m. Dal Col, J. Marconi, L. Codourey, J. Mannino, L. Georgiou, E. Menoud, M. Carleton, A. Rodriguez, I. 2024-05-14 doi:10.1101/2024.05.13.593837 Cold Spring Harbor Laboratory Press 2024-05-14 <![CDATA[ plantMASST - Community-driven chemotaxonomic digitization of plants ]]> https://biorxiv.org/content/10.1101/2024.05.13.593988v1?rss=1 Gomes, P. W. P. Mannochio-Russo, H. Schmid, R. Zuffa, S. Damiani, T. Quiros-Guerrero, L.-M. Caraballo-Rodriguez, A. M. Zhao, H. N. Yang, H. Xing, S. Charron-Lamoureux, V. Chigumba, D. N. Sedio, B. E. Myers, J. A. Allard, P.-M. Harwood, T. V. Tamayo-Castillo, G. Kang, K. B. Defossez, E. Koolen, H. H. F. da Silva, M. N. e Silva, C. Y. Y. Rasmann, S. Walker, T. W. N. Glauser, G. Chaves-Fallas, J. M. David, B. Kim, H. Lee, K. H. Kim, M. J. Choi, W. J. Keum, Y.-S. de Lima, E. J. S. P. de Medeiros, L. S. Bataglion, G. A. Costa, E. V. da Silva, F. M. A. Carvalho, 2024-05-15 doi:10.1101/2024.05.13.593988 Cold Spring Harbor Laboratory Press 2024-05-15 <![CDATA[ Biomathematical enzyme kinetics model of prebiotic autocatalytic RNA networks: degenerating parasite-specific hyperparasite catalysts confer parasite resistance and herald the birth of molecular immunity ]]> https://biorxiv.org/content/10.1101/2024.05.14.594066v1?rss=1 Conrad, B. Pirovino, M. Iseli, C. Curran, J. A. 2024-05-17 doi:10.1101/2024.05.14.594066 Cold Spring Harbor Laboratory Press 2024-05-17 <![CDATA[ Selective molecular inhibition of the HDAC6 ZnF-UBP binding domain impairs multiple myeloma cell proliferation ]]> https://biorxiv.org/content/10.1101/2024.05.14.594071v1?rss=1 Rincon, R. Coira, I. F. Richieu, A. Attana, F. Urwyler, M. Haider, S. Bourquin, C. Bertrand, P. Cuendet, M. 2024-05-17 doi:10.1101/2024.05.14.594071 Cold Spring Harbor Laboratory Press 2024-05-17 <![CDATA[ Neural correlates of embodied and vibratory mechanisms associated with vocal emotion production ]]> https://biorxiv.org/content/10.1101/2024.05.14.594073v1?rss=1 Selosse, G. Grandjean, D. Ceravolo, L. 2024-05-14 doi:10.1101/2024.05.14.594073 Cold Spring Harbor Laboratory Press 2024-05-14 <![CDATA[ Protein structure, a genetic encoding for glycosylation ]]> https://biorxiv.org/content/10.1101/2024.05.15.594261v1?rss=1 Kellman, B. Sandoval, D. Zaytseva, O. Brock, K. Baboo, S. Nachmanson, D. Irvine, E. Armingol, E. Mih, N. Zhang, Y. Jeffris, M. Bartels, P. Nguyen, T. Tam, A. Gasman, S. Ilan, S. Shamie, I. Diedrich, J. Wang, X. van Woudenbergh, E. Altman, M. Aylward, A. Bao, B. Castro, A. Sorrentino, J. Chiang, A. Campbell, M. Bartsch, Y. Aguilar-Calvo, P. Sigurdson, C. Alter, G. Lauc, G. Yates, Y. Marks, D. Lisacek, F. Lewis, N. 2024-05-15 doi:10.1101/2024.05.15.594261 Cold Spring Harbor Laboratory Press 2024-05-15 <![CDATA[ Decoding glycosylation potential from protein structure across human glycoproteins with a multi-view recurrent neural network ]]> https://biorxiv.org/content/10.1101/2024.05.15.594334v1?rss=1 Kellman, B. Mariethoz, J. Zhang, Y. Shaul, S. Jeffris, M. Sandoval, D. Jeffris, M. Armingol, E. Bao, B. Lisacek, F. Bojar, D. Lewis, N. 2024-05-15 doi:10.1101/2024.05.15.594334 Cold Spring Harbor Laboratory Press 2024-05-15 <![CDATA[ A phosphate-binding pocket in cyclin B3 is essential for XErp1/Emi2 degradation in meiosis I ]]> https://biorxiv.org/content/10.1101/2024.05.16.594477v1?rss=1 Demmig, R. Schaefer, M. Johannes, E. Heim, A. Boland, A. Mayer, T. U. 2024-05-16 doi:10.1101/2024.05.16.594477 Cold Spring Harbor Laboratory Press 2024-05-16 <![CDATA[ Consistency of resting-state correlations between fMRI networks and EEG band-power ]]> https://biorxiv.org/content/10.1101/2024.05.22.595342v1?rss=1 Xavier, M. Esteves, I. Jorge, J. Abreu, R. Giraud, A.-L. Sadaghiani, S. Wirsich, J. Figueiredo, P. 2024-05-22 doi:10.1101/2024.05.22.595342 Cold Spring Harbor Laboratory Press 2024-05-22 <![CDATA[ Antibacterial effectors in Dictyostelium discoideum: specific activity against different bacterial species ]]> https://biorxiv.org/content/10.1101/2024.05.30.596688v1?rss=1 Munoz-Ruiz, R. Lamrabet, O. Jauslin, T. Guilhen, C. Bourbon, A. Cosson, P. 2024-06-03 doi:10.1101/2024.05.30.596688 Cold Spring Harbor Laboratory Press 2024-06-03 <![CDATA[ An implantable biohybrid nerve model towards synaptic deep brain stimulation ]]> https://biorxiv.org/content/10.1101/2024.05.31.596665v1?rss=1 Sifringer, L. Fratzl, A. Clement, B. F. Chansoria, P. Mönkemöller, L. Duru, J. Ihle, S. J. Steffens, S. Beltraminelli, A. Ceylan, E. Hengsteler, J. Maurer, B. Weaver, S. M. Tringides, C. M. Vulic, K. Madduri, S. Zenobi-Wong, M. Roska, B. Vörös, J. Ruff, T. 2024-06-03 doi:10.1101/2024.05.31.596665 Cold Spring Harbor Laboratory Press 2024-06-03 <![CDATA[ Reliability of structural brain change in cognitively healthy adult samples. ]]> https://biorxiv.org/content/10.1101/2024.06.03.592804v1?rss=1 Vidal-Pineiro, D. Sorensen, O. Stromstad, M. Amlien, I. K. Anderson, M. Baare, W. F. C. Bartres-Faz, D. Brandmaier, A. M. Brathen, A. C. Garrido, P. Ghisletta, P. Grydeland, H. Henson, R. N. Kievit, R. A. Kormacher, M. Kuhn, S. Lindenberger, U. Mowinckel, A. M. Nyberg, L. Roe, J. M. Sneve, M. H. Sole-Padulles, C. Watne, L.-O. Walhovd, K. B. Fjell, A. M. 2024-06-03 doi:10.1101/2024.06.03.592804 Cold Spring Harbor Laboratory Press 2024-06-03 <![CDATA[ TORC1 reactivation by pheromone signaling revealed by phosphoproteomics of fission yeast sexual reproduction ]]> https://biorxiv.org/content/10.1101/2024.06.04.597361v1?rss=1 Berard, M. Merlini, L. Martin, S. G. 2024-06-06 doi:10.1101/2024.06.04.597361 Cold Spring Harbor Laboratory Press 2024-06-06 <![CDATA[ Local increases in admixture with hunter-gatherers followed the initial expansion of Neolithic farmers across continental Europe ]]> https://biorxiv.org/content/10.1101/2024.06.10.598301v1?rss=1 Tsoupas, A. Reyna-Blanco, C. S. Quilodran, C. S. Blöcher, J. Brami, M. Wegmann, D. Burger, J. Currat, M. 2024-06-12 doi:10.1101/2024.06.10.598301 Cold Spring Harbor Laboratory Press 2024-06-12 <![CDATA[ Permanent lymphocyte subset elimination upon a single dose of AAV-delivered depletion antibody dissects immune control of chronic viral infection ]]> https://biorxiv.org/content/10.1101/2024.06.19.599723v1?rss=1 Kastner, A. L. Marx, A.-F. Dimitrova, M. Abreu-Mota, T. Ertuna, Y. I. Bonilla, W. V. Stauffer, K. Wagner, I. Kreutzfeldt, M. Merkler, D. Pinschewer, D. D. 2024-06-21 doi:10.1101/2024.06.19.599723 Cold Spring Harbor Laboratory Press 2024-06-21 <![CDATA[ Epigenomic programming of peripheral monocytes determines their transcriptional response to the tumor microenvironment ]]> https://biorxiv.org/content/10.1101/2024.06.19.599675v1?rss=1 Kiss, M. Halasz, L. Hadadi, E. Berger, W. K. Tzerpos, P. Poliska, S. Kancheva, D. Debraekeleer, A. Brughmans, J. Elkrim, Y. Martens, L. Saeys, Y. Daniel, B. Czimmerer, Z. Laoui, D. Nagy, L. Van Ginderachter, J. A. 2024-06-23 doi:10.1101/2024.06.19.599675 Cold Spring Harbor Laboratory Press 2024-06-23 <![CDATA[ Modulation of Microtubule Dynamics by Monovalent Ions ]]> https://biorxiv.org/content/10.1101/2024.06.26.600768v1?rss=1 Aumeier, C. Fernandes, S. 2024-06-26 doi:10.1101/2024.06.26.600768 Cold Spring Harbor Laboratory Press 2024-06-26 <![CDATA[ Investigating Ligand-Mediated Conformational Dynamics of Pre-miR21: A Machine-Learning-Aided Enhanced Sampling Study ]]> https://biorxiv.org/content/10.1101/2024.06.27.601024v1?rss=1 View larger version (36K): org.highwire.dtl.DTLVardef@188857borg.highwire.dtl.DTLVardef@1f37d2forg.highwire.dtl.DTLVardef@9fc9dforg.highwire.dtl.DTLVardef@7e8629_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Aureli, S. Bellina, F. Rizzi, V. Gervasio, F. L. 2024-07-02 doi:10.1101/2024.06.27.601024 Cold Spring Harbor Laboratory Press 2024-07-02 <![CDATA[ Functional monocentricity with holocentric characteristics andchromosome-specific centromeres in a stick insect ]]> https://biorxiv.org/content/10.1101/2024.06.30.601385v1?rss=1 Toubiana, W. Dumas, Z. Tran Van, P. Parker, D. J. Merel, V. Schubert, V. Aury, J.-M. Bournonville, L. Cruaud, C. Houben, A. Istace, B. Labadie, K. Noel, B. Schwander, T. 2024-07-02 doi:10.1101/2024.06.30.601385 Cold Spring Harbor Laboratory Press 2024-07-02 <![CDATA[ Evolutionarily conserved principles of ESCRT-III-mediated membrane remodelling revealed by a two-subunit Asgard archaeal system ]]> https://biorxiv.org/content/10.1101/2024.07.01.601590v1?rss=1 Souza, D. P. Espadas, J. Chaaban, S. Moody, E. R. R. Hatano, T. Balasubramanian, M. Williams, T. A. Roux, A. Baum, B. 2024-07-02 doi:10.1101/2024.07.01.601590 Cold Spring Harbor Laboratory Press 2024-07-02 <![CDATA[ Cytosolic N6AMT1-dependent translation supports mitochondrial RNA processing ]]> https://biorxiv.org/content/10.1101/2024.07.02.601698v1?rss=1 Foged, M. M. Recazens, E. Chollet, S. Lisci, M. Allen, G. E. Zinshteyn, B. Boutguetait, D. Munch, C. A. Mootha, V. K. Jourdain, A. A. 2024-07-02 doi:10.1101/2024.07.02.601698 Cold Spring Harbor Laboratory Press 2024-07-02 <![CDATA[ eLemur: A cellular-resolution 3D atlas of the mouse lemur brain ]]> https://biorxiv.org/content/10.1101/2024.07.05.601641v1?rss=1 Jeon, H. Kim, J. Kim, J. Choi, Y. K. Ho, A. C. L. Pifferi, F. Huber, D. Feng, L. Kim, J. 2024-07-08 doi:10.1101/2024.07.05.601641 Cold Spring Harbor Laboratory Press 2024-07-08 <![CDATA[ Actin dynamics sustains spatial gradients of membrane tension in adherent cells ]]> https://biorxiv.org/content/10.1101/2024.07.15.603517v1?rss=1 Garcia-Arcos, J. M. Mehidi, A. Sanchez Velazquez, J. Guillamat, P. Tomba, C. Houzet, L. Capolupo, L. D'Angelo, G. Colom, A. Hinde, E. Aumeier, C. Roux, A. 2024-07-16 doi:10.1101/2024.07.15.603517 Cold Spring Harbor Laboratory Press 2024-07-16 <![CDATA[ CTCF-DEPENDENT INSULATION OF Hoxb13 AND THE HETEROCHRONIC CONTROL OF TAIL LENGTH ]]> https://biorxiv.org/content/10.1101/2024.07.20.604409v1?rss=1 Lopez-Delisle, L. Zakany, J. Bochaton, C. OSTEIL, P. Mayran, A. Darbellay, F. Mascrez, B. Rekaik, H. Duboule, D. 2024-07-23 doi:10.1101/2024.07.20.604409 Cold Spring Harbor Laboratory Press 2024-07-23 <![CDATA[ Somatic hypermutation-mediated paratope flexibility improves the cross-reactivity of human malaria antibodies ]]> https://biorxiv.org/content/10.1101/2024.07.24.604858v1?rss=1 Murugan, R. Hanke, A. Oludada, O. E. Costa, G. Flores-Garcia, Y. Mustafa, G. Li, K. Huntwork, R. H. C. Horn, G. Sekaran, M. Tomaras, G. Zavala, F. Levashina, E. A. Ketchem, R. R. Wade, R. C. Wardemann, H. 2024-07-24 doi:10.1101/2024.07.24.604858 Cold Spring Harbor Laboratory Press 2024-07-24 <![CDATA[ Aerolysin nanopore structure revealed at high resolution in lipid environment ]]> https://biorxiv.org/content/10.1101/2024.08.12.607338v1?rss=1 Anton, J. Iacovache, I. Bada Juarez, J. F. Abriata, L. Perrin, L. Cao, C. Marcaida, M. J. Zuber, B. Dal Peraro, M. 2024-08-12 doi:10.1101/2024.08.12.607338 Cold Spring Harbor Laboratory Press 2024-08-12 <![CDATA[ Platelet-derived LPA16:0 inhibits adult neurogenesis and stress resilience in anxiety disorder ]]> https://biorxiv.org/content/10.1101/2024.08.18.608479v1?rss=1 Larrieu, T. Carron, C. Grieco, F. Weber, C. Ginggen, K. Delacretaz, A. Gallart-Ayala, H. Tsuda, M. Cameron, H. Eap, C. Ivanisevic, J. Magistretti, P. Telley, L. Dayer, A. Piguet, C. Toni, N. 2024-08-19 doi:10.1101/2024.08.18.608479 Cold Spring Harbor Laboratory Press 2024-08-19 <![CDATA[ Membrane microdomains are crucial for Mycobacterium marinum EsxA-dependent membrane damage, escape to the cytosol and infection ]]> https://biorxiv.org/content/10.1101/2024.08.19.608731v1?rss=1 Bosmani, C. Perret, A. Leuba, F. Gueho, A. Hanna, N. Soldati, T. 2024-08-20 doi:10.1101/2024.08.19.608731 Cold Spring Harbor Laboratory Press 2024-08-20 <![CDATA[ Asymmetry of acto-myosin cortices as active fluids shape cells in organoids ]]> https://biorxiv.org/content/10.1101/2024.08.22.609097v1?rss=1 Guyomar, T. Lu, L. Hiraiwa, T. Riveline, D. 2024-08-22 doi:10.1101/2024.08.22.609097 Cold Spring Harbor Laboratory Press 2024-08-22 <![CDATA[ Host-Guest binding free energies a la carte: an automated OneOPES protocol ]]> https://biorxiv.org/content/10.1101/2024.08.23.609378v1?rss=1 Febrer Martinez, P. Rizzi, V. Aureli, S. Gervasio, F. L. 2024-08-24 doi:10.1101/2024.08.23.609378 Cold Spring Harbor Laboratory Press 2024-08-24 <![CDATA[ Unlocking new avenues for non-invasive brain monitoring with combined electroencephalography and functional magnetic resonance imaging at ultra-high field ]]> https://biorxiv.org/content/10.1101/2024.08.23.609301v1?rss=1 Sainz Martinez, C. Wirsich, J. Jager, C. Warbrick, T. Vulliemoz, S. Lemay, M. Bastiaansen, J. Wiest, R. Jorge, J. 2024-08-26 doi:10.1101/2024.08.23.609301 Cold Spring Harbor Laboratory Press 2024-08-26 <![CDATA[ Lamellar Schwann cells in the Pacinian corpuscle potentiate vibration perception ]]> https://biorxiv.org/content/10.1101/2024.08.23.609459v1?rss=1 Chen, Y.-T. de Thomas Wagner, D. Loutit, A. J. Nourizonoz, A. Croisier-Coeytaux, M.-C. Blanc, J. Knott, G. Lee, K.-S. Huber, D. 2024-08-26 doi:10.1101/2024.08.23.609459 Cold Spring Harbor Laboratory Press 2024-08-26 <![CDATA[ NEBULA101: an open dataset for the study of language aptitude in behaviour, brain structure and function ]]> https://biorxiv.org/content/10.1101/2024.08.27.609682v1?rss=1 Rampinini, A. C. Balboni, I. Kepinska, O. Berthele, R. Golestani, N. 2024-08-28 doi:10.1101/2024.08.27.609682 Cold Spring Harbor Laboratory Press 2024-08-28 <![CDATA[ SNAP-tag2: faster and brighter protein labeling ]]> https://biorxiv.org/content/10.1101/2024.08.28.610127v1?rss=1 Kühn, S. Nasufovic, V. Wilhelm, J. Kompa, J. de Lange, E. M. F. Lin, Y.-H. Egoldt, C. Fischer, J. Lennoi, A. Tarnawski, M. Reinstein, J. Vlijm, R. Hiblot, J. Johnsson, K. 2024-08-29 doi:10.1101/2024.08.28.610127 Cold Spring Harbor Laboratory Press 2024-08-29 <![CDATA[ RNG2 tethers the conoid to the apical polar ring in Toxoplasma gondii: a key mechanism in parasite motility and invasion ]]> https://biorxiv.org/content/10.1101/2024.08.29.610260v1?rss=1 Haase, R. Ren, B. Dos Santos Pacheco, N. Visentin, R. Maco, B. Mondragon Flores, R. Vadas, O. Soldati-Favre, D. 2024-08-29 doi:10.1101/2024.08.29.610260 Cold Spring Harbor Laboratory Press 2024-08-29 <![CDATA[ Brain Charts for the Rhesus Macaque Lifespan ]]> https://biorxiv.org/content/10.1101/2024.08.28.610193v1?rss=1 Alldritt, S. Ramirez, J. S. B. Vos de Wael, R. Bethlehem, R. Seidlitz, J. Wang, Z. Nenning, K.-H. Esper, N. B. Smallwood, J. Franco, A. R. Byeon, K. Alexander-Bloch, A. Messinger, A. Chen, A. Thiele, A. Weiss, A. R. Shmuel, A. Fox, A. Tusche, A. Brambrink, A. M. Falchier, A. Hiba, B. Jarraya, B. Jung, B. Butler, B. Russ, B. E. Howell, B. R. Drzewiecki, C. M. Guedj, C. Schwiedrzik, C. M. Amiez, C. Wilson, C. R. E. Klink, C. Kroenke, C. Constantinidis, C. Garin, C. M. Poirier, C. Gale, D. J. Leopold, D. A. Rudko, D. A. Amaral, D. G. Tsao, D. Cook, D. J. 2024-08-30 doi:10.1101/2024.08.28.610193 Cold Spring Harbor Laboratory Press 2024-08-30 <![CDATA[ Genomic characterization of plasmids harboring blaNDM-1,-5,-7 carbapenemase alleles in clinical Klebsiella pneumoniae in Pakistan ]]> https://biorxiv.org/content/10.1101/2024.09.06.611696v1?rss=1 Qamar, M. U. Sierra, R. Jabeen, K. Rizwan, M. Rashid, A. Dar, Y. Andrey, D. O. 2024-09-09 doi:10.1101/2024.09.06.611696 Cold Spring Harbor Laboratory Press 2024-09-09 <![CDATA[ Rare twin cysteine residues in the HIV-1 envelope variable region 1 link to neutralization escape and breadth development ]]> https://biorxiv.org/content/10.1101/2024.09.05.611179v1?rss=1 65,000 V1 sequences from the CATNAP database, the AMP trials and three large longitudinal HIV infection cohorts, the SHCS, ZPHI and CAPRISA studies, we show that Env variants with extra V1 Cys are present at low levels throughout infection and fluctuate in frequency over time within participants. We demonstrate an independent association of extra V1 Cys with elite plasma neutralization, and a strong preference for two versus one extra Cys, suggesting certain Envs introduce an additional disulfide bond for stabilization. We observed high levels of neutralization resistance among Envs from 34 bNAb donors, of which 17.6% had elongated V1 regions with extra Cys. We show that extra V1 Cys moderately increase neutralization resistance in an Env from a V2- Apex bNAb-inducer. Modulation of the accessibility of bNAb epitopes on this Env by extra V1 Cys enhanced epitope shielding of several regions, but increased V2 exposure. This suggests that escape from autologous neutralizing activity drove insertion of the extra V1 Cys, creating a modified antigen that may have favored V2 bNAb induction in this donor. Overall, we identify a rare motif of twin Cys in V1 that confers increased neutralization resistance and Env stabilization, is associated with bNAb induction, and may hold potential for incorporation into future HIV bNAb immunogens. ]]> Hesselman, M. C. Zeeb, M. Rusert, P. Pasin, C. Mamrosh, J. Kariuki, S. Sickmann, M. Kaufmann, M. M. Schmidt, D. Friedrich, N. Metzner, K. J. Rindler, A. Kuster, H. Adams, C. Thebus, R. Huber, M. Yerly, S. Leuzinger, K. Perreau, M. Koller, R. Dollenmaier, G. Frigerio, S. Westfall, D. H. Deng, W. DeCamp, A. C. Juraska, M. Edupuganti, S. Mgodi, N. Murrell, H. Garrett, N. Wagh, K. Mullins, J. I. Williamson, C. Moore, P. L. Günthard, H. F. Kouyos, R. D. Trkola, A. 2024-09-10 doi:10.1101/2024.09.05.611179 Cold Spring Harbor Laboratory Press 2024-09-10 <![CDATA[ A novel biomechanical model of the mouse forelimb predicts muscle activity in optimal control simulations of reaching movements ]]> https://biorxiv.org/content/10.1101/2024.09.05.611289v1?rss=1 Gilmer, J. I. Coltman, S. K. Velasco, G. C. Hutchinson, J. Huber, D. Person, A. L. Al Borno, M. 2024-09-10 doi:10.1101/2024.09.05.611289 Cold Spring Harbor Laboratory Press 2024-09-10 <![CDATA[ Synergistic cross-kingdom host cell damage between Candida albicans and Enterococcus faecalis ]]> https://biorxiv.org/content/10.1101/2024.09.11.612452v1?rss=1 Kapitan, M. Niemiec, M. J. Millet, N. Brandt, P. Chowdhury, M. E. K. Czapka, A. Abdissa, K. Hoffmann, F. Lange, A. Veleba, M. Nietzsche, S. Mosig, A. S. Loffler, B. Marquet, M. Makarewicz, O. Kline, K. A. Vylkova, S. Swidergall, M. Jacobsen, I. D. 2024-09-13 doi:10.1101/2024.09.11.612452 Cold Spring Harbor Laboratory Press 2024-09-13 <![CDATA[ The preferential injury of outer renal medulla after ischemia-reperfusion relies on high oxidative metabolism ]]> https://biorxiv.org/content/10.1101/2024.09.12.612245v1?rss=1 Arnoux, G. Serre, J. Verissimo, T. Tihy, M. Placier, S. Verney, C. Sangla, F. Paolucci, D. Fernandez, M. de Seigneux, S. Sgardello, S. Naesens, M. Hadchouel, J. Feraille, E. Khodo, S. N. Galichon, P. Legouis, D. 2024-09-14 doi:10.1101/2024.09.12.612245 Cold Spring Harbor Laboratory Press 2024-09-14 <![CDATA[ Profiling the physiological impact of aberrant folded-state protein filamentation in cells ]]> https://biorxiv.org/content/10.1101/2024.09.13.612878v1?rss=1 View larger version (84K): org.highwire.dtl.DTLVardef@7136a4org.highwire.dtl.DTLVardef@ba62dborg.highwire.dtl.DTLVardef@b02bbaorg.highwire.dtl.DTLVardef@6cbf9_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Levin, T. Garcia-Seisdedos, H. Lobov, A. Wojtynek, M. Alexandrov, A. Jona, G. Levi, D. Medalia, O. Levy, E. D. 2024-09-14 doi:10.1101/2024.09.13.612878 Cold Spring Harbor Laboratory Press 2024-09-14 <![CDATA[ Exploiting correlations across trials and behavioral sessions to improve neural decoding ]]> https://biorxiv.org/content/10.1101/2024.09.14.613047v1?rss=1 Zhang, Y. Lyu, H. Hurwitz, C. Wang, S. Findling, C. L. Hubert, F. Pouget, A. International Brain Laboratory, Varol, E. Paninski, L. 2024-09-15 doi:10.1101/2024.09.14.613047 Cold Spring Harbor Laboratory Press 2024-09-15 <![CDATA[ A combined approach to extract rotational dynamics of globular proteins undergoing liquid-liquid phase separation ]]> https://biorxiv.org/content/10.1101/2024.09.17.613388v1?rss=1 Gendreizig, D. Kalarikkal, A. Holtbrügge, S. L. Mukherjee, S. Galazzo, L. Kucher, S. Rosspeintner, A. Schäfer, L. V. Bordignon, E. 2024-09-18 doi:10.1101/2024.09.17.613388 Cold Spring Harbor Laboratory Press 2024-09-18 <![CDATA[ Directional Cell-to-cell Transport in Plant Roots ]]> https://biorxiv.org/content/10.1101/2024.09.16.613234v1?rss=1 Jacquier, L. Fiorenza, C. Robe, K. Han, J.-P. Cleard, F. Fuchs, C. Ramakrishna, P. Loubery, S. Lefebvre-Legendre, L. Barberon, M. 2024-09-19 doi:10.1101/2024.09.16.613234 Cold Spring Harbor Laboratory Press 2024-09-19 <![CDATA[ How interactions between temperature and resources scale from populations to communities ]]> https://biorxiv.org/content/10.1101/2024.09.19.613936v1?rss=1 Kremer, C. T. Thomas, M. K. Klausmeier, C. A. Litchman, E. 2024-09-23 doi:10.1101/2024.09.19.613936 Cold Spring Harbor Laboratory Press 2024-09-23 <![CDATA[ Revisiting sour rot of grapevine through disease-associated microbiomes: a tripartite co-infection? ]]> https://biorxiv.org/content/10.1101/2024.09.19.613941v1?rss=1 Hevin, S. Wilhelm, M. Kehrli, P. Buyck, B. Gindro, K. Wolfender, J.-L. Hofstetter, V. 2024-09-24 doi:10.1101/2024.09.19.613941 Cold Spring Harbor Laboratory Press 2024-09-24 <![CDATA[ Super-enhancer profiling reveals ThPOK/ZBTB7B, a CD4+ cell lineage commitment factor, as a master regulator that restricts breast cancer cells to a luminal non-migratory phenotype ]]> https://biorxiv.org/content/10.1101/2024.09.21.614267v1?rss=1 Arcuschin, C. D. Kahrizi, K. Sayaman, R. W. DiBenedetto, C. Shen, Y. Salaberry, P. J. Zakroui, O. Schwarzer, C. Scapozza, A. Betancur, P. Saba, J. D. Coppe, J.-P. Barcellos-Hoff, M. H. Kappes, D. van 't Veer, L. Schor, I. E. Munoz, D. P. 2024-09-24 doi:10.1101/2024.09.21.614267 Cold Spring Harbor Laboratory Press 2024-09-24 <![CDATA[ Repeated low-intensity focused ultrasound led to microglial profile changes at long term in TgF344-AD rats ]]> https://biorxiv.org/content/10.1101/2024.09.25.614692v1?rss=1 Abjean, L. Novell, A. Larrat, B. Gueorguiev, B. R. Cailly, T. Fossey, C. Fabis, F. Salomir, R. Tsartsalis, S. Tournier, B. B. Millet, P. Ceyzeriat, K. 2024-09-27 doi:10.1101/2024.09.25.614692 Cold Spring Harbor Laboratory Press 2024-09-27 <![CDATA[ The Immune Landscape of Tumor-Associated Macrophage Reprogramming ]]> https://biorxiv.org/content/10.1101/2024.09.25.614962v1?rss=1 Duval, F. Lourenco, J. Hicham, M. Boivin, G. Guichard, A. Wyser-Rmili, C. Fournier, N. De Palma, M. Mansouri, N. 2024-09-27 doi:10.1101/2024.09.25.614962 Cold Spring Harbor Laboratory Press 2024-09-27 <![CDATA[ Growth compensation upon changes in tissue size in the Drosophila abdomen ]]> https://biorxiv.org/content/10.1101/2024.10.02.616326v1?rss=1 Ferreira, A. Cairoli, A. Mangione, F. Holder, M. V. Ainslie, A. Aerne, B. L. Salbreux, G. Tapon, N. 2024-10-03 doi:10.1101/2024.10.02.616326 Cold Spring Harbor Laboratory Press 2024-10-03 <![CDATA[ The C. elegans homolog of Sjögrens Syndrome Nuclear Antigen 1 is required for the structural integrity of the centriole and bipolar mitotic spindle assembly ]]> https://biorxiv.org/content/10.1101/2024.10.03.616528v1?rss=1 Pfister, J. A. Agostini, L. Bournonville, L. Sankaralingam, P. Bell, Z. G. Hamel, V. Guichard, P. Biertumpfel, C. Mizuno, N. O'Connell, K. F. 2024-10-04 doi:10.1101/2024.10.03.616528 Cold Spring Harbor Laboratory Press 2024-10-04 <![CDATA[ The A-C Linker controls centriole cohesion and duplication ]]> https://biorxiv.org/content/10.1101/2024.10.04.616628v1?rss=1 Bournonville, L. Laporte, M. H. Borgers, S. Guichard, P. Hamel, V. 2024-10-04 doi:10.1101/2024.10.04.616628 Cold Spring Harbor Laboratory Press 2024-10-04 <![CDATA[ Structure and function of the yeast amino acid-sensing SEAC-EGOC supercomplex ]]> https://biorxiv.org/content/10.1101/2024.10.05.616782v1?rss=1 Tafur, L. Bonadei, L. Zheng, Y. Loewith, R. 2024-10-05 doi:10.1101/2024.10.05.616782 Cold Spring Harbor Laboratory Press 2024-10-05 <![CDATA[ Animal acoustic communication maintains a universal optimum rhythm ]]> https://biorxiv.org/content/10.1101/2024.10.07.616955v1?rss=1 Piette, T. Cathcart, C. Barbieri, C. Martin Ming, K. Grandjean, D. Bickel, B. Deaux, E. Giraud, A.-L. 2024-10-07 doi:10.1101/2024.10.07.616955 Cold Spring Harbor Laboratory Press 2024-10-07 <![CDATA[ Comparative single-cell analyses reveal evolutionary repurposing of a conserved gene program in bat wing development ]]> https://biorxiv.org/content/10.1101/2024.10.10.617585v1?rss=1 Schindler, M. Feregrino, C. Aldrovandi, S. Lo, B.-W. Monaco, A. A. Ringel, A. R. Morales, A. Zehnder, T. Behncke, R. Y. Glaser, J. Barclay, A. Andrey, G. Kragesteen, B. K. Hagerling, R. Haas, S. A. Vingron, M. Ulitsky, I. Marti-Renom, M. Hechavarria, J. C. Fasel, N. J. Hiller, M. Lupianez, D. Mundlos, S. Real, F. M. 2024-10-13 doi:10.1101/2024.10.10.617585 Cold Spring Harbor Laboratory Press 2024-10-13 <![CDATA[ Cell shape noise strength regulates shape dynamics during EMT-associated cell spreading ]]> https://biorxiv.org/content/10.1101/2024.10.14.618199v1?rss=1 Poenisch, W. Yanakieva, I. Salbreux, G. Paluch, E. K. 2024-10-15 doi:10.1101/2024.10.14.618199 Cold Spring Harbor Laboratory Press 2024-10-15 <![CDATA[ Cell-extrinsic controls over neocortical neuron fate and diversity ]]> https://biorxiv.org/content/10.1101/2024.10.15.618395v1?rss=1 Baumann, N. Morassut, I. Puiggros, S. R. Klingler, E. Bartolini, G. Fievre, S. Jabaudon, D. 2024-10-16 doi:10.1101/2024.10.15.618395 Cold Spring Harbor Laboratory Press 2024-10-16 <![CDATA[ Functional study of Phaeodactylum tricornutum Seipin homolog highlights unique features of lipid droplets biogenesis in diatoms. ]]> https://biorxiv.org/content/10.1101/2024.10.11.617903v1?rss=1 Le Moigne, D. Richard, F. Albrieux, C. Mahieu, M. Arrighi, M. Si Larbi, G. jouneau, P.-H. Gros, V. Louwagie, M. Roy, S. Amari, C. Carletti, M. Bonnarde, R. Gong, Y. Pan, Y. Hu, H. Bastien, O. Jouhet, J. Amato, A. Marechal, E. Salvaing, J. 2024-10-17 doi:10.1101/2024.10.11.617903 Cold Spring Harbor Laboratory Press 2024-10-17 <![CDATA[ Mindfulness training impacts brain network dynamics linked to stress response in young adolescents. ]]> https://biorxiv.org/content/10.1101/2024.10.16.616959v1?rss=1 Gaviria, J. Celen, Z. Peek, L. Magnus, M. Brosset, S. Vuilleumier, P. Van De Ville, D. Merglen, A. Klauser, P. Piguet, C. 2024-10-17 doi:10.1101/2024.10.16.616959 Cold Spring Harbor Laboratory Press 2024-10-17 <![CDATA[ Computational generation of long-range axonal morphologies ]]> https://biorxiv.org/content/10.1101/2024.10.16.618695v1?rss=1 Berchet, A. Petkantchin, R. Markram, H. Kanari, L. 2024-10-18 doi:10.1101/2024.10.16.618695 Cold Spring Harbor Laboratory Press 2024-10-18 <![CDATA[ Charting the landscape of cytoskeletal diversity in microbial eukaryotes ]]> https://biorxiv.org/content/10.1101/2024.10.18.618984v1?rss=1 Mikus, F. Ramos, A. R. Shah, H. Olivetta, M. Borgers, S. Hellgoth, J. Saint-Donat, C. Araujo, M. Bhickta, C. Cherek, P. Bilbao, J. Txurruka, E. Leisch, N. Schwab, Y. Husnik, F. Seoane, S. Probert, I. Guichard, P. Hamel, V. Dey, G. Dudin, O. 2024-10-18 doi:10.1101/2024.10.18.618984 Cold Spring Harbor Laboratory Press 2024-10-18 <![CDATA[ TORC2-regulated sterol redistribution mediates recovery from membrane perturbation by small amphipathic molecules. ]]> https://biorxiv.org/content/10.1101/2024.10.18.618785v1?rss=1 Tettamanti, M. G. Nowak, P. Kusmider, B. Kefauver, J. M. Mercier, V. Roux, A. Loewith, R. 2024-10-19 doi:10.1101/2024.10.18.618785 Cold Spring Harbor Laboratory Press 2024-10-19 <![CDATA[ New assessment of teichoic acids in the cell envelope of Streptococcus pneumoniae ]]> https://biorxiv.org/content/10.1101/2024.10.18.619035v1?rss=1 Mai, N. Bauda, E. Boyat, C. Laguri, C. Freton, C. Chouquet, A. Gallet, B. Baudoin, M. Wong, Y.-S. Grangeasse, C. Moriscot, C. Durmort, C. Zapun, A. Morlot, C. 2024-10-19 doi:10.1101/2024.10.18.619035 Cold Spring Harbor Laboratory Press 2024-10-19 <![CDATA[ Functional and causal neural mechanisms of human voice perception in noisy situations ]]> https://biorxiv.org/content/10.1101/2024.10.21.619396v1?rss=1 Ceravolo, L. Scariati, E. Fruhholz, S. Van De Ville, D. Grandjean, D. 2024-10-22 doi:10.1101/2024.10.21.619396 Cold Spring Harbor Laboratory Press 2024-10-22 <![CDATA[ The claustrum is critical for maintaining working memory information ]]> https://biorxiv.org/content/10.1101/2024.10.28.620649v1?rss=1 Bhattacharjee, A. S. Huber, C. Unsal, B. Renfer, J.-R. Rodriguez, I. Carleton, A. 2024-10-28 doi:10.1101/2024.10.28.620649 Cold Spring Harbor Laboratory Press 2024-10-28 <![CDATA[ A mitochondrial redox switch licenses the onset of morphogenesis in animals ]]> https://biorxiv.org/content/10.1101/2024.10.28.620733v1?rss=1 Kahlin, U. Dalla Ricca, F. Pillai, S. J. Olivetta, M. Tharp, K. M. Jao, L.-E. Dudin, O. McDonald, K. L. Aydogan, M. G. 2024-10-29 doi:10.1101/2024.10.28.620733 Cold Spring Harbor Laboratory Press 2024-10-29 <![CDATA[ Secondary motor cortex tracks decision value and supports behavioral flexibility during non-instructed choice ]]> https://biorxiv.org/content/10.1101/2024.10.29.620931v1?rss=1 Augusto, E. Kouskoff, V. Chenouard, N. Giraudet, M. Peltier, L. de Miranda, A. Louis, A. Alonso, L. Gambino, F. 2024-10-31 doi:10.1101/2024.10.29.620931 Cold Spring Harbor Laboratory Press 2024-10-31 <![CDATA[ A hierarchical coordinate system for sequence memory in human entorhinal cortex. ]]> https://biorxiv.org/content/10.1101/2024.10.30.620612v1?rss=1 Shpektor, A. Bakermans, J. J. W. Baram, A. B. Sarnthein, J. Ledergerber, D. Imbach, L. Muller-Seydlitz, E. Barron, H. C. Behrens, T. E. J. 2024-10-31 doi:10.1101/2024.10.30.620612 Cold Spring Harbor Laboratory Press 2024-10-31 <![CDATA[ Multiscale Quantification of Hemispheric Asymmetry in Cortical Maps Using Geometric Eigenmodes ]]> https://biorxiv.org/content/10.1101/2024.10.31.621232v1?rss=1 Milloz, A. Vogel, J. Olsen, A. Pang, J. C. Strandberg, O. Anijärv, T. E. Stomrud, E. Palmqvist, S. Spotorno, N. Ossenkoppele, R. Van De Ville, D. Hansson, O. Behjat, H. 2024-10-31 doi:10.1101/2024.10.31.621232 Cold Spring Harbor Laboratory Press 2024-10-31 <![CDATA[ Four ZIPs contribute to Zn, Fe, Cu and Mn acquisition at the outer root domain ]]> https://biorxiv.org/content/10.1101/2024.10.31.621270v1?rss=1 ROBE, K. Legendre-Lefebvre, L. Cleard, F. Barberon, M. 2024-11-02 doi:10.1101/2024.10.31.621270 Cold Spring Harbor Laboratory Press 2024-11-02 <![CDATA[ Critical assay parameters facilitating confident detection of expression changes, fusions and short variants in RNA isolated from tissue ]]> https://biorxiv.org/content/10.1101/2024.10.30.621018v1?rss=1 Kubik, S. Matyszczak, I. Toda, N. Magrinelli, E. Helleboid, P.-Y. Smith, E. Bezrukov, F. Ryder, C. Lopez, J. Harle, A. Xu, Z. 2024-11-03 doi:10.1101/2024.10.30.621018 Cold Spring Harbor Laboratory Press 2024-11-03 <![CDATA[ ER sensing of lipid metabolism drives PRA family-dependent regulation of COPII vesicle transport ]]> https://biorxiv.org/content/10.1101/2024.11.07.622448v1?rss=1 Nakazato, M. Nakamura, H. Kato, M. Ikema, R. Iguchi, M. Hanaoka, K. Eto, K. Karashima, T. Ikeda, A. Yabuki, Y. Schlarmann, P. Manzano-Lopez, J. Aguilera-Romero, A. Sabido-Bozo, S. Perez-Linero, A. M. Kana, M. Iefuji, H. Riezman, I. Riezman, H. Muniz, M. Funato, K. 2024-11-11 doi:10.1101/2024.11.07.622448 Cold Spring Harbor Laboratory Press 2024-11-11 <![CDATA[ Telomeric transposons are pervasive in linear bacterial genomes ]]> https://biorxiv.org/content/10.1101/2024.11.13.623437v1?rss=1 Hsieh, S.-C. Fülöp, M. Schargel, R. Petassi, M. T. Barabas, O. Peters, J. E. 2024-11-13 doi:10.1101/2024.11.13.623437 Cold Spring Harbor Laboratory Press 2024-11-13 <![CDATA[ Differential Engagement of Associative-Limbic and Sensorimotor Regions of the Cerebellum and Basal Ganglia in Explicit vs. Implicit Emotional Processing ]]> https://biorxiv.org/content/10.1101/2024.11.20.624507v1?rss=1 Ceravolo, L. Thomasson, M. Constantin, I. M. Chassot, E. Pierce, J. Cionca, A. Grandjean, D. Assal, F. Peron, J. 2024-11-21 doi:10.1101/2024.11.20.624507 Cold Spring Harbor Laboratory Press 2024-11-21 <![CDATA[ Old age variably impacts chimpanzee engagement and efficiency in stone tool use ]]> https://biorxiv.org/content/10.1101/2024.11.25.625128v1?rss=1 Howard-Spink, E. Matsuzawa, T. Carvalho, S. Hobaiter, C. Almeida-Warren, K. Gruber, T. Biro, D. 2024-11-25 doi:10.1101/2024.11.25.625128 Cold Spring Harbor Laboratory Press 2024-11-25 <![CDATA[ The Dictyostelium discoideum - Mycobacterium marinum infection model, a powerful high throughput screening platform for anti-infective compounds ]]> https://biorxiv.org/content/10.1101/2024.12.03.626613v1?rss=1 Nitschke, J. Hanna, N. Soldati, T. 2024-12-03 doi:10.1101/2024.12.03.626613 Cold Spring Harbor Laboratory Press 2024-12-03 <![CDATA[ Molecular cloning and host range analysis of three cytomegaloviruses from Mastomys natalensis ]]> https://biorxiv.org/content/10.1101/2024.12.05.626976v1?rss=1 Staliunaite, L. Puhach, O. Ostermann, E. Rosenke, K. Nichols, J. Oestereich, L. Feldmann, H. Davison, A. J. Jarvis, M. A. Brune, W. 2024-12-05 doi:10.1101/2024.12.05.626976 Cold Spring Harbor Laboratory Press 2024-12-05 <![CDATA[ Cold stress involves CBF dependent regulatory pathway to remodel wood formation in Eucalyptus gunnii hybrids. ]]> https://biorxiv.org/content/10.1101/2024.12.11.627904v1?rss=1 Bachir, I. H. Ployet, R. San Clemente, H. Aguilar, M. Dupas, A. Ladouce, N. Martinez, Y. Pettenati, J. G. Teulieres, C. Cassan-Wang, H. Mounet, F. 2024-12-12 doi:10.1101/2024.12.11.627904 Cold Spring Harbor Laboratory Press 2024-12-12 <![CDATA[ Modification of the microstructure of the CERN- CLEAR-VHEE beam at the picosecond scale modifies ZFE morphogenesis but has no impact on hydrogen peroxide production. ]]> https://biorxiv.org/content/10.1101/2024.12.19.629203v1?rss=1 View larger version (22K): org.highwire.dtl.DTLVardef@1df896aorg.highwire.dtl.DTLVardef@b6b824org.highwire.dtl.DTLVardef@1f35964org.highwire.dtl.DTLVardef@171d60f_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Kacem, H. Kunz, L. Korysko, P. Ollivier, J. Tsoutsou, P. Martinotti, A. Rieker, V. Bateman, J. Farabolini, W. Baldacchino, G. Loo, B. W. Limoli, C. W. Dosanjh, M. Corsini, R. Vozenin, M.-C. 2024-12-20 doi:10.1101/2024.12.19.629203 Cold Spring Harbor Laboratory Press 2024-12-20 <![CDATA[ Global patterns of genetic admixture reveal effects of language contact ]]> https://biorxiv.org/content/10.1101/2024.12.19.629340v1?rss=1 Graff, A. Blasi, D. E. Ringen, E. J. Bajic, V. Bavelier, D. Shimizu, K. K. Pakendorf, B. Barbieri, C. Bickel, B. 2024-12-20 doi:10.1101/2024.12.19.629340 Cold Spring Harbor Laboratory Press 2024-12-20 <![CDATA[ The biophysical mechanism of mitochondrial pearling ]]> https://biorxiv.org/content/10.1101/2024.12.21.629509v1?rss=1 Sturm, G. Hake, K. Lefebvre, A. E. Y. T. Rux, C. J. Ivanova, D. Millett-Sikking, A. Tharp, K. M. Rao, B. Closser, M. Waite, A. Precido-Lopez, M. Dumont, S. Lu, W. Manley, S. Landoni, J. C. Marshall, W. F. 2024-12-22 doi:10.1101/2024.12.21.629509 Cold Spring Harbor Laboratory Press 2024-12-22 <![CDATA[ VSIG4-Expressing Macrophages Contribute To Anti-Parasitic And Anti-Metastatic Responses In The Peritoneal Cavity ]]> https://biorxiv.org/content/10.1101/2024.12.23.630094v1?rss=1 Van Ginderachter, J. A. Lebegge, E. Kancheva, D. Van Craenenbroeck, J. Ernst, S. Bardet, P. M. R. Caro, A. A. Kiss, M. Jumapili, N. A. Mora Barthelmess, R. Zivalj, M. Assaf, N. Elkrim, Y. Demuytere, J. De Jonge, J. Raes, G. Hadadi, E. Devoogdt, N. Vincke, C. Vereecke, L. Ceelen, W. Stijlemans, B. Laoui, D. Arnouk, S. M. 2024-12-24 doi:10.1101/2024.12.23.630094 Cold Spring Harbor Laboratory Press 2024-12-24 <![CDATA[ Brain activation for language and its relationship to cognitive and linguistic measures ]]> https://biorxiv.org/content/10.1101/2024.12.31.630909v1?rss=1 Balboni, I. Rampinini, A. Kepinska, O. Berthele, R. Golestani, N. 2025-01-01 doi:10.1101/2024.12.31.630909 Cold Spring Harbor Laboratory Press 2025-01-01 <![CDATA[ SDS-22 stabilizes the PP1 catalytic subunits GSP-1/-2 contributing to polarity establishment in C. elegans embryos ]]> https://biorxiv.org/content/10.1101/2025.01.07.631699v1?rss=1 Gotta, M. Li, Y. Calvi, I. 2025-01-08 doi:10.1101/2025.01.07.631699 Cold Spring Harbor Laboratory Press 2025-01-08 <![CDATA[ Pluripotency factors enhance the firing efficiency of late DNA replication origins in mouse embryonic stem cells ]]> https://biorxiv.org/content/10.1101/2025.01.07.631761v1?rss=1 Rodriguez-Carballo, E. Dionellis, V. S. Ntallis, S. G. Bernasconi, L. Keskin, E. Halazonetis, T. 2025-01-08 doi:10.1101/2025.01.07.631761 Cold Spring Harbor Laboratory Press 2025-01-08 <![CDATA[ EPISeg: Automated segmentation of the spinal cord on echo planar images using open-access multi-center data ]]> https://biorxiv.org/content/10.1101/2025.01.07.631402v1?rss=1 Banerjee, R. Kaptan, M. Tinnermann, A. Khatibi, A. Dabbagh, A. Kündig, C. W. Law, C. S. W. Pfyffer, D. Lythgoe, D. J. Tsivaka, D. Van De Ville, D. Eippert, F. Muhammad, F. Glover, G. H. David, G. Haynes, G. Haaker, J. Brooks, J. C. W. Finsterbusch, J. Martucci, K. T. Hemmerling, K. J. Mobarak-Abadi, M. Hoggarth, M. A. Howard, M. A. Bright, M. G. Kinany, N. Kowalczyk, O. S. Freund, P. Barry, R. L. Mackey, S. Vahdat, S. Schading, S. McMahon, S. B. Parish, T. Marchand-Pauvert, V. Chen, Y. Smith, Z. A. Weber, K. A. De Leener, B. Cohen-Adad, J. 2025-01-10 doi:10.1101/2025.01.07.631402 Cold Spring Harbor Laboratory Press 2025-01-10 <![CDATA[ Neural correlates of approach and avoidance tendencies toward physical activity and sedentary stimuli: An fMRI study ]]> https://biorxiv.org/content/10.1101/2025.01.10.632302v1?rss=1 Cheval, B. Ceravolo, L. Igloi, K. Sander, D. Zimmermann, M. Van Ruitenbeek, P. Boisgontier, M. P. 2025-01-12 doi:10.1101/2025.01.10.632302 Cold Spring Harbor Laboratory Press 2025-01-12 <![CDATA[ High Performance protocol for ultra-short DNA sequencing using Oxford Nanopore Technology (ONT) ]]> https://biorxiv.org/content/10.1101/2025.01.10.632410v1?rss=1 View larger version (40K): org.highwire.dtl.DTLVardef@1c99f4eorg.highwire.dtl.DTLVardef@1f9cf50org.highwire.dtl.DTLVardef@199c8acorg.highwire.dtl.DTLVardef@1459f48_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Zemaitis, L. Palepsiene, R. Juzenas, S. Alzbutas, G. Burgi, P.-Y. Heinis, T. Charmet, J. Angeloni Suter, S. Jost, M. Raisutis, R. Simmel, F. Galminas, I. 2025-01-12 doi:10.1101/2025.01.10.632410 Cold Spring Harbor Laboratory Press 2025-01-12 <![CDATA[ SAPID: a Strategy to Analyze Plant Extracts Taste In Depth. Application to the complex tasteof Swertia chirayita (Roxb.) H.Karst. ]]> https://biorxiv.org/content/10.1101/2025.01.11.628830v1?rss=1 View larger version (30K): org.highwire.dtl.DTLVardef@1b0c4a3org.highwire.dtl.DTLVardef@3db05aorg.highwire.dtl.DTLVardef@50ddeorg.highwire.dtl.DTLVardef@1d16adb_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Rutz, A. Deneulin, P. Tonutti, I. Bach, B. Wolfender, J.-L. 2025-01-12 doi:10.1101/2025.01.11.628830 Cold Spring Harbor Laboratory Press 2025-01-12 <![CDATA[ Tissular glucocorticoid reactivating enzyme 11beta-HSD1 drives pathogenic myofibroblast differentiation in chronic kidney disease ]]> https://biorxiv.org/content/10.1101/2025.01.09.631985v1?rss=1 Arnoux, G. Legouis, D. Tihy, M. Yvon, R. Liaudet, N. Moser, S. Poinot, H. SASSI, A. Lempke, O. Fernandez, M. Monnay, I. Chassot, A. Bourquin, C. Moll, S. Somm, E. Rutkowski, J. M. Wenger, R. H. Naesens, M. Odermatt, A. Nlandu Khodo, S. Pommier, A. Feraille, E. 2025-01-13 doi:10.1101/2025.01.09.631985 Cold Spring Harbor Laboratory Press 2025-01-13 <![CDATA[ Distinct modes of dopamine modulation on striatopallidal synaptic transmission ]]> https://biorxiv.org/content/10.1101/2025.01.15.633147v1?rss=1 Lee, Y. Reva, M. Kim, K. J. Kim, Y. Cho, E. Kim, H.-j. Jeong, M. Myung, K. Li, Y. Lee, S. E. Kim, E. Lee, C. J. J. Luscher, C. Kim, J.-I. 2025-01-15 doi:10.1101/2025.01.15.633147 Cold Spring Harbor Laboratory Press 2025-01-15 <![CDATA[ A High-Throughput Bone Marrow 3D Co-Culture System to Develop Resistance to B Cell Receptor Signaling Targeted Agents in B Cell Non-Hodgkin Lymphoma ]]> https://biorxiv.org/content/10.1101/2025.01.14.632958v1?rss=1 View larger version (36K): org.highwire.dtl.DTLVardef@72bc6aorg.highwire.dtl.DTLVardef@afdda2org.highwire.dtl.DTLVardef@1fff494org.highwire.dtl.DTLVardef@11252cf_HPS_FORMAT_FIGEXP M_FIG O_FLOATNOVisual AbstractC_FLOATNO C_FIG ]]> Zadro, A. Arribas, A. J. Colombo, M. V. Cannas, E. Spriano, F. Cascione, L. Mensah, A. A. Simonetta, F. Petta, D. Arrigoni, C. Candrian, C. Moretti, M. Bertoni, F. 2025-01-19 doi:10.1101/2025.01.14.632958 Cold Spring Harbor Laboratory Press 2025-01-19 <![CDATA[ p16.1 and p16.2, new HSPC markers, play redundant roles in zebrafish T-cell lymphopoiesis ]]> https://biorxiv.org/content/10.1101/2025.01.21.634058v1?rss=1 Gomez, E. Li, R. A. BERTRAND, J. Y. 2025-01-21 doi:10.1101/2025.01.21.634058 Cold Spring Harbor Laboratory Press 2025-01-21 <![CDATA[ Co-translational assembly promotes functional diversification of paralogous proteins ]]> https://biorxiv.org/content/10.1101/2025.01.22.634331v1?rss=1 View larger version (53K): org.highwire.dtl.DTLVardef@b17418org.highwire.dtl.DTLVardef@3d0a61org.highwire.dtl.DTLVardef@1747aeaorg.highwire.dtl.DTLVardef@31b931_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Mallik, S. Cisneros, A. F. Landry, C. Levy, E. D. 2025-01-23 doi:10.1101/2025.01.22.634331 Cold Spring Harbor Laboratory Press 2025-01-23 <![CDATA[ Decaying and expanding Erk gradients process memory of skeletal size during zebrafish fin regeneration ]]> https://biorxiv.org/content/10.1101/2025.01.23.634576v1?rss=1 Rich, A. Li, Z. De Simone, A. Garcia, L. Janssen, J. Ando, K. Ou, J. Vergassola, M. Poss, K. D. Di Talia, S. 2025-01-23 doi:10.1101/2025.01.23.634576 Cold Spring Harbor Laboratory Press 2025-01-23 <![CDATA[ Cross-species comparative modelling of antimicrobial host responses ex vivo in human and murine precision cut lung slices and in vivo in mice ]]> https://biorxiv.org/content/10.1101/2025.01.27.634989v1?rss=1 Choltus, H. Prados, J. Bianchi, N. Heikkila, N. Serre-Beinier, V. Karenovics, W. Badat, B. Eberhardt, C. Becattini, S. Schmolke, M. 2025-01-27 doi:10.1101/2025.01.27.634989 Cold Spring Harbor Laboratory Press 2025-01-27 <![CDATA[ Perilysosomal Ca2+ overload impairs autophagic degradation in β-cell lipotoxicity ]]> https://biorxiv.org/content/10.1101/2025.01.27.635047v1?rss=1 Nguyen, H. T. Ly, L. D. Ngo, T. T. T. Lee, S. K. Noriega Polo, C. Lee, S. Lee, T. Cha, S.-K. Lee, M.-S. Wiederkehr, A. Wollheim, C. B. Park, K.-S. 2025-01-29 doi:10.1101/2025.01.27.635047 Cold Spring Harbor Laboratory Press 2025-01-29 <![CDATA[ Enterococcus faecalis-derived lactic acid facilitates persistent and polymicrobial wound infections by suppressing macrophage activation ]]> https://biorxiv.org/content/10.1101/2025.01.31.635924v1?rss=1 View larger version (34K): org.highwire.dtl.DTLVardef@2e1565org.highwire.dtl.DTLVardef@17eaf85org.highwire.dtl.DTLVardef@356139org.highwire.dtl.DTLVardef@821581_HPS_FORMAT_FIGEXP M_FIG C_FIG Highlights- E. faecalis lactate dehydrogenase mutants fail to acidify the environment and cannot suppress NF-{kappa}B signaling. - Lactic acid is necessary and sufficient to drive NF-{kappa}B suppression in macrophages. - Lactic acid NF-{kappa}B suppression is relayed through two complementary routes: MCT- 1 transport and the lactate sensor GPR81. - MCT-1-dependent signaling blunts ERK/STAT3 phosphorylation, lowering MyD88 levels; whereas GPR81 drives YAP phosphorylation, reducing NF-{kappa}B activation. - E. faecalis-derived lactic acid drives immunosuppression, potentiates persistence, and promotes multi-species wound infection in vivo. ]]> da Silva, R. A. G. Tien, B. Y. Q. Kao, P. H. N. Celik, C. Tan, A. Z. C. Ismail, M. H. Hu, G. Chong, K. K. L. Thibault, G. Chen, J. Kline, K. A. 2025-01-31 doi:10.1101/2025.01.31.635924 Cold Spring Harbor Laboratory Press 2025-01-31 <![CDATA[ BlueBerry: Closed-loop wireless optogenetic manipulation in freely moving animals ]]> https://biorxiv.org/content/10.1101/2025.01.30.635697v1?rss=1 Nourizonoz, A. Girard, B. Guyoton, M. Galinanes, G. Thurnherr, R. Pellat, S. Bellone, C. Huber, D. 2025-02-01 doi:10.1101/2025.01.30.635697 Cold Spring Harbor Laboratory Press 2025-02-01 <![CDATA[ Fsr quorum sensing system restricts biofilm growth and activates inflammation in enterococcal infective endocarditis ]]> https://biorxiv.org/content/10.1101/2025.02.07.636843v1?rss=1 Antypas, H. Schmidtchen, V. Staiger, W. I. Li, Y. Tan, R. J. W. Ng, K. K. F. Neo, C. J. Y. Radhesh, S. M. Tanoto, F. R. da Silva, R. A. G. Colomer Winter, C. Manzano, C. Wong, J. J. Pethe, K. Hasse, B. Brugger, S. D. Wong, S. L. Van Tyne, D. Zinkernagel, A. S. Kline, K. A. 2025-02-07 doi:10.1101/2025.02.07.636843 Cold Spring Harbor Laboratory Press 2025-02-07 <![CDATA[ Human gut microbiota subspecies carry implicit information for in-depth microbiome research ]]> https://biorxiv.org/content/10.1101/2025.02.05.636567v1?rss=1 Trickovic, M. Kieser, S. Zdobnov, E. M. Trajkovski, M. 2025-02-08 doi:10.1101/2025.02.05.636567 Cold Spring Harbor Laboratory Press 2025-02-08 <![CDATA[ Cross-Species Biomechanical Determinants of Shape Diversity ]]> https://biorxiv.org/content/10.1101/2025.02.07.637025v1?rss=1 Bailleul, R. Cuny, N. Khoromoskaia, D. Basu, S. Bergamini, G. Cucurachi, P. Rupp, S. Guse, A. Curantz, C. Swinhoe, N. Cleves, P. Craggs, J. Fujita, S. Nakajima, Y. Steenbergen, P. Diz-Munoz, A. Salbreux, G. Ikmi, A. 2025-02-08 doi:10.1101/2025.02.07.637025 Cold Spring Harbor Laboratory Press 2025-02-08 <![CDATA[ Insect wings arose with a genetic circuit that extends the useful range of a BMP morphogen ]]> https://biorxiv.org/content/10.1101/2025.02.07.637038v1?rss=1 Huang, A. Cocconi, L. Nicholls-Mindlin, B. Alexandre, C. Salbreux, G. Vincent, J.-P. 2025-02-08 doi:10.1101/2025.02.07.637038 Cold Spring Harbor Laboratory Press 2025-02-08 <![CDATA[ Age- and Virus-Specific Signatures of In Vitro Reconstituted Human Airway Epithelia in the Presence and Absence of Respiratory Viral Infections ]]> https://biorxiv.org/content/10.1101/2025.02.16.638411v1?rss=1 Bellon, M. Alvarez, C. Buendia, G. R. Sattonnet-Roche, P. Dbeissi, D. Sarmiento, Y. Kaiser, L. Didierlaurent, A. M. Eckerle, I. Essaidi-Laziosi, M. 2025-02-17 doi:10.1101/2025.02.16.638411 Cold Spring Harbor Laboratory Press 2025-02-17 <![CDATA[ TimeFlow: a density-driven pseudotime method for flowcytometry data analysis ]]> https://biorxiv.org/content/10.1101/2025.02.16.638508v1?rss=1 Liarou, M. Matthes, T. Marchand-Maillet, S. 2025-02-21 doi:10.1101/2025.02.16.638508 Cold Spring Harbor Laboratory Press 2025-02-21 <![CDATA[ NEDD4 promotes Sertoli cell proliferation and adult Leydig cell differentiation in the murine testis ]]> https://biorxiv.org/content/10.1101/2025.02.19.639149v1?rss=1 Windley, S. P. Neirijnck, Y. Vidovic, D. Schwarz, Q. Kumar, S. Nef, S. Wilhelm, D. 2025-02-23 doi:10.1101/2025.02.19.639149 Cold Spring Harbor Laboratory Press 2025-02-23 <![CDATA[ Biological subtyping of autism via cross-species fMRI ]]> https://biorxiv.org/content/10.1101/2025.03.04.641400v1?rss=1 Pagani, M. Zerbi, V. Gini, S. Alvino, F. Banerjee, A. Barberis, A. Basson, A. Bozzi, Y. Galbusera, A. Ellegood, J. Fagiolini, M. Lerch, J. Matteoli, M. Montani, C. Pozzi, D. Provenzano, G. Scattoni, M. L. Wenderoth, N. Xu, T. Lombardo, M. Milham, M. Di Martino, A. Gozzi, A. 2025-03-05 doi:10.1101/2025.03.04.641400 Cold Spring Harbor Laboratory Press 2025-03-05 <![CDATA[ Revealing Water-Mediated Activation Mechanisms in the Beta 1-Adrenergic Receptor via OneOPES-Enhanced Free Energy Landscapes ]]> https://biorxiv.org/content/10.1101/2025.03.03.641221v1?rss=1 Aureli, S. Rizzi, V. Piasentin, N. Gervasio, F. L. 2025-03-10 doi:10.1101/2025.03.03.641221 Cold Spring Harbor Laboratory Press 2025-03-10 <![CDATA[ The impact of intrinsic connectome dynamics on perception is context-dependent ]]> https://biorxiv.org/content/10.1101/2025.03.06.641785v1?rss=1 20s), we examined how pre-stimulus connectome states influenced the perception of upcoming ambiguous stimuli on a trial-by-trial basis across these tasks. Using Support Vector Machine (SVM) models, we demonstrated that pre-stimulus connectome states can predict the perception of upcoming ambiguous or threshold stimuli. At the connection level, we found that distinct sets of task-specific connections enabled these predictions for each task. No single connection was associated with perceptual outcomes across multiple tasks. Predictive connections in all tasks spanned both the task-relevant sensory modality network and high-order cognitive control networks. Only when averaged to the level of intrinsic connectivity networks did perceptually predictive connectivity show some similarity among pairs of tasks. Our findings highlight the functional significance of ongoing connectome states for moment-to-moment behavior, demonstrating that this relationship is largely context-dependent. ]]> Mostame, P. Hesselmann, G. Bido-Medina, R. Kleinschmidt, A. Sadaghiani, S. 2025-03-10 doi:10.1101/2025.03.06.641785 Cold Spring Harbor Laboratory Press 2025-03-10 <![CDATA[ A pharmacological modality to sequester homomeric proteins ]]> https://biorxiv.org/content/10.1101/2025.03.05.641597v1?rss=1 Livnah, E. Suss, O. Rogel, A. Gilat, A. Abdan, Y. Villegas, J. D. Tivon, B. Albeck, S. Unger, T. Golani, O. Goliand, I. Margulies, D. Levy, E. D. London, N. 2025-03-11 doi:10.1101/2025.03.05.641597 Cold Spring Harbor Laboratory Press 2025-03-11 <![CDATA[ LEMMIv2: Benchmarking Framework for Metagenomic and 16S Amplicon Profilers with a Catalogue of Evaluated Tools. ]]> https://biorxiv.org/content/10.1101/2025.03.06.641904v1?rss=1 Seppey, M. Benavides, A. Berkeley, M. Manni, M. Zdobnov, E. M. 2025-03-11 doi:10.1101/2025.03.06.641904 Cold Spring Harbor Laboratory Press 2025-03-11 <![CDATA[ Transgenerational maintenance of H3K27me3 heterochromatin is balanced by chromodomain proteins in Caenorhabditis elegans ]]> https://biorxiv.org/content/10.1101/2025.03.07.642071v1?rss=1 Ozdemir, I. Hoefler, A. Delaney, K. Wenda, J. M. Li, C. Saltzman, A. L. Boland, A. Steiner, F. A. 2025-03-11 doi:10.1101/2025.03.07.642071 Cold Spring Harbor Laboratory Press 2025-03-11 <![CDATA[ Cap-adjacent 2'-O-ribose methylation of RNA in C. elegans is required for postembryonic growth and germline development in the presence of the decapping exonuclease EOL-1 ]]> https://biorxiv.org/content/10.1101/2025.03.10.638824v1?rss=1 View larger version (19K): org.highwire.dtl.DTLVardef@1cd906dorg.highwire.dtl.DTLVardef@c4e922org.highwire.dtl.DTLVardef@1a5c2dborg.highwire.dtl.DTLVardef@19be5d8_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Clemens, E. Brivio, S. Al-Khafaji, M. Eijlers, P. Kurukulasuriya, M. MacLeod, D. Haussmann, I. Wenzel, M. Mueller, B. Soller, M. Pettitt, J. 2025-03-11 doi:10.1101/2025.03.10.638824 Cold Spring Harbor Laboratory Press 2025-03-11 <![CDATA[ Brain neuromarkers predict self- and other-related mentalizing across adult, clinical, and developmental samples ]]> https://biorxiv.org/content/10.1101/2025.03.10.642438v1?rss=1 Acil, D. Andrews-Hanna, J. R. Lopez-Sola, M. van Buuren, M. Krabbendam, L. Zhang, L. van der Meer, L. Fuentes-Claramonte, P. Pomarol-Clotet, E. Salvador, R. Debbane, M. Vrticka, P. Vuilleumier, P. Sbarra, D. A. Coppola, A. M. White, L. O. Wager, T. D. Koban, L. 2025-03-12 doi:10.1101/2025.03.10.642438 Cold Spring Harbor Laboratory Press 2025-03-12 <![CDATA[ Cell-free Reconstitution Reveals Synergistic Stabilization of Microtubule Doublets by PACRG and FAP20 ]]> https://biorxiv.org/content/10.1101/2025.03.12.642377v1?rss=1 Khuntsariya, D. Batman, U. Krishnan, A. Rozbesky, D. Lemaitre, F. Janke, C. Hamel, V. Guichard, P. Braun, M. Lansky, Z. 2025-03-12 doi:10.1101/2025.03.12.642377 Cold Spring Harbor Laboratory Press 2025-03-12 <![CDATA[ Aryl N-acetamide compounds exert antimalarial activity by acting as agonists of rhomboid protease PfROM8 and cation channel PfCSC1. ]]> https://biorxiv.org/content/10.1101/2025.03.18.644039v1?rss=1 Boulet, C. Modak, J. K. Counihan, N. A. Parkyn Schneider, M. Nguyen, W. Dans, M. G. Barnes, C. B. G. Razook, Z. McCann, k. Barry, A. E. Crabb, B. S. de Koning-Ward, T. F. Gilson, P. R. 2025-03-19 doi:10.1101/2025.03.18.644039 Cold Spring Harbor Laboratory Press 2025-03-19 <![CDATA[ Light propofol anaesthesia for non-invasive auditory EEG recording in unrestrained non-human primates. ]]> https://biorxiv.org/content/10.1101/2025.03.24.644890v1?rss=1 Piette, T. Lacaux, C. Scheltienne, M. Sterpenich, V. Isnardon, M. Moulin, V. Cermolacce, A. Grandjean, D. Meguerditchian, A. Deaux, E. Giraud, A.-L. 2025-03-24 doi:10.1101/2025.03.24.644890 Cold Spring Harbor Laboratory Press 2025-03-24 <![CDATA[ Neural dynamics of induced vocal tract vibrations during vocal emotion recognition ]]> https://biorxiv.org/content/10.1101/2025.03.24.644945v1?rss=1 Selosse, G. Benis, D. Greilsamer, J. Meuleman, B. Grandjean, D. Ceravolo, L. 2025-03-24 doi:10.1101/2025.03.24.644945 Cold Spring Harbor Laboratory Press 2025-03-24 <![CDATA[ Targeting CXCR4-expressing TAMs in muscle-invasive bladder cancer to enhance tumor control after immunotherapy ]]> https://biorxiv.org/content/10.1101/2025.03.21.644543v1?rss=1 Despond, E. El Ahanidi, H. Alouche, N. Zdimerova, H. Favre, S. Zanette, G. Nassiri, S. Benamran, D. Tsantoulis, P. Attaleb, M. Maby El Hajjami, H. Dagher, J. Gourhand, V. Balabanian, k. Espeli, M. Luther, S. A. Jandus, C. Leblond, M. M. Verdeil, G. 2025-03-25 doi:10.1101/2025.03.21.644543 Cold Spring Harbor Laboratory Press 2025-03-25 <![CDATA[ Substrate recognition by human separase ]]> https://biorxiv.org/content/10.1101/2025.03.24.644901v1?rss=1 Yu, J. Schmidt, S. Botto, M. Lee, K. Ghent, C. M. Goodfried, J. M. Howe, A. O'Reilly, F. J. Morgan, D. O. Boland, A. 2025-03-26 doi:10.1101/2025.03.24.644901 Cold Spring Harbor Laboratory Press 2025-03-26 <![CDATA[ Non-linear microglial, inflammatory and oligodendrocyte dynamics across stages of Alzheimer's disease ]]> https://biorxiv.org/content/10.1101/2025.03.25.645240v1?rss=1 View larger version (52K): org.highwire.dtl.DTLVardef@eb5f3forg.highwire.dtl.DTLVardef@ba239eorg.highwire.dtl.DTLVardef@7897feorg.highwire.dtl.DTLVardef@142a6fd_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Badina, A. M. Ceyzeriat, K. Amosse, Q. Tresh, A. Abjean, L. Guenat, L. Vauthey, E. Tsartsalis, S. Millet, P. Tournier, B. B. 2025-03-26 doi:10.1101/2025.03.25.645240 Cold Spring Harbor Laboratory Press 2025-03-26 <![CDATA[ Dissecting the Crosstalk Between Dopaminergic and Serotonergic Systems in the Striatum ]]> https://biorxiv.org/content/10.1101/2025.03.28.645922v1?rss=1 Liu, Y. Traba, J. E. Luscher, C. 2025-03-29 doi:10.1101/2025.03.28.645922 Cold Spring Harbor Laboratory Press 2025-03-29 <![CDATA[ CtBP1 coordinates synaptic, metabolic and contractile changes induced by denervation in skeletal muscle ]]> https://biorxiv.org/content/10.1101/2025.03.29.646097v1?rss=1 Cattaneo, O. Lopez, G. Rajendran, J. Chabry, F. Prola, A. Liaudet, N. Startchik, S. Castets, P. 2025-04-03 doi:10.1101/2025.03.29.646097 Cold Spring Harbor Laboratory Press 2025-04-03 <![CDATA[ Spatiotemporal organisation of residual disease in mouse and human BRCA1-deficient mammary tumours and breast cancer ]]> https://biorxiv.org/content/10.1101/2025.04.02.646768v1?rss=1 Turos, D. Decollogny, M. Chanfon, A. Siffert, M. Romanens, L. Tille, J.-C. Tredan, O. Labidi-Galy, I. Valdeolivas, A. Rottenberg, S. 2025-04-03 doi:10.1101/2025.04.02.646768 Cold Spring Harbor Laboratory Press 2025-04-03 <![CDATA[ Whole-night gentle rocking improves sleep in poor sleepers with insomnia complaints. ]]> https://biorxiv.org/content/10.1101/2025.03.31.646264v1?rss=1 Perrault, A. A. Cross, N. E. Dang Vu, T. T. Schwartz, S. Bayer, L. 2025-04-05 doi:10.1101/2025.03.31.646264 Cold Spring Harbor Laboratory Press 2025-04-05 <![CDATA[ Transcription factor LHX2 suppresses astrocyte proliferation in the postnatal mammalian cerebral cortex ]]> https://biorxiv.org/content/10.1101/2025.04.10.648067v1?rss=1 Iyer, A. Fronteiro, R. Bhatia, P. Kumari, S. Singh, A. Zhou, J. Bocchi, R. Narayanan, R. Tole, S. 2025-04-10 doi:10.1101/2025.04.10.648067 Cold Spring Harbor Laboratory Press 2025-04-10 <![CDATA[ Spatial Adaptation of Primate Retinal Ganglion Cells between Artificial and Natural Stimuli ]]> https://biorxiv.org/content/10.1101/2025.04.09.647910v1?rss=1 Vystrcilova, M. Sridhar, S. Burg, M. F. Khani, M. H. Karamanlis, D. Schreyer, H. M. Ramakrishna, V. Krüppel, S. Zapp, S. J. Mietsch, M. Gollisch, T. Ecker, A. S. 2025-04-15 doi:10.1101/2025.04.09.647910 Cold Spring Harbor Laboratory Press 2025-04-15 <![CDATA[ Phase Separation and a Hydrodynamic Instability Localize Proteins at Growing Microtubule Ends ]]> https://biorxiv.org/content/10.1101/2025.04.11.648094v1?rss=1 Schaer, J. Miesch, J. Catapano, V. Dumoulin, L. Tran, J. Velluz, M.-C. Aumeier, C. Kruse, K. 2025-04-17 doi:10.1101/2025.04.11.648094 Cold Spring Harbor Laboratory Press 2025-04-17 <![CDATA[ Unveiling the Molecular Architecture of T Cells and Immune Synapses with Cryo-Expansion Microscopy ]]> https://biorxiv.org/content/10.1101/2025.04.15.648816v1?rss=1 Lemaitre, F. Mercey, O. Mean, I. Paulin, E. Dutoit, V. Rath, J. Migliorini, D. Arber, C. Guichard, P. HAMEL, v. Wolf, B. 2025-04-20 doi:10.1101/2025.04.15.648816 Cold Spring Harbor Laboratory Press 2025-04-20 <![CDATA[ Bioengineering of the implantable vascularized endocrine constructs for insulin delivery suitable for clinical upscaling ]]> https://biorxiv.org/content/10.1101/2025.04.19.647461v1?rss=1 Bellofatto, K. Lebreton, F. Hassany, M. Hanna, R. Bignard, J. Marteyn, A. Mar Fonseca, L. Campo, F. Olgasi, C. Wolf-van Buerck, L. Honarpisheh, M. MARTINEZ DE TEJADA WEBER, B. Follenzi, A. Citro, A. Piemonti, L. THAUNAT, O. Seissler, J. COMPAGNON, P. cohen, m. BERISHVILI, E. VANGUARD consortium, 2025-04-23 doi:10.1101/2025.04.19.647461 Cold Spring Harbor Laboratory Press 2025-04-23 <![CDATA[ A Dual Homeostatic Regulation of Dry Mass and Volume Defines a Target Density in Proliferating Mammalian Cells ]]> https://biorxiv.org/content/10.1101/2025.04.24.650395v1?rss=1 Srivastava, N. Calabrese, L. Plancke, C. Rollin, R. Venkova, L. Havas, K. Cosentino Lagomarsino, M. Piel, M. 2025-04-25 doi:10.1101/2025.04.24.650395 Cold Spring Harbor Laboratory Press 2025-04-25 <![CDATA[ Neurogliaform cells mediate interhemispheric modulation of sensory-evoked activity in cortical pyramidal neurons ]]> https://biorxiv.org/content/10.1101/2025.04.30.651595v1?rss=1 Markopoulos, F. Chrereau, R. Brandalise, F. Chippalkatti, V. Prados, J. Dayer, A. Holtmaat, A. 2025-05-01 doi:10.1101/2025.04.30.651595 Cold Spring Harbor Laboratory Press 2025-05-01 <![CDATA[ High levels of Cdc42 GTPase underlie an all-or-none decision to fuse ]]> https://biorxiv.org/content/10.1101/2025.05.05.652171v1?rss=1 Saha, S. Sajeevan, A. Merlini, L. Vincenzetti, V. Martin, S. G. 2025-05-06 doi:10.1101/2025.05.05.652171 Cold Spring Harbor Laboratory Press 2025-05-06 <![CDATA[ Within- and Between-Assessor Reliability of Lower-Limb Inter-Joint Coordination During Gait in Individuals With and Without Cerebral Palsy ]]> https://biorxiv.org/content/10.1101/2025.05.01.651648v1?rss=1 Dussault Picard, C. Cherni, Y. Fonseca, M. Carcreff, L. Leboeuf, F. Armand, S. 2025-05-07 doi:10.1101/2025.05.01.651648 Cold Spring Harbor Laboratory Press 2025-05-07 <![CDATA[ Ultrathin Liquid Cells for Microsecond Time-Resolved Cryo-EM ]]> https://biorxiv.org/content/10.1101/2025.05.05.652279v1?rss=1 Curtis, W. A. Hruby, J. Kruger, C. R. Barrass, S. V. Drabbels, M. Lorenz, U. J. 2025-05-07 doi:10.1101/2025.05.05.652279 Cold Spring Harbor Laboratory Press 2025-05-07 <![CDATA[ Spatial control of secretory vesicle targeting by the Ync13-Rga7-Rng10 complex during cytokinesis ]]> https://biorxiv.org/content/10.1101/2025.05.13.653810v1?rss=1 Zhang, S. Singh, D. Zhu, Y.-H. Zhang, K. J. Melero, A. Martin, S. G. Wu, J.-Q. 2025-05-14 doi:10.1101/2025.05.13.653810 Cold Spring Harbor Laboratory Press 2025-05-14 <![CDATA[ Mechanism-driven screening of membrane-targeting and pore-forming antimicrobial peptides ]]> https://biorxiv.org/content/10.1101/2025.05.17.654650v1?rss=1 Li, J. Yang, C. Dong, R. Bada Juarez, J. F. Wang, L. Wettstein, M. E. Wang, D. Cao, C. Lu, Y. Song, C. 2025-05-21 doi:10.1101/2025.05.17.654650 Cold Spring Harbor Laboratory Press 2025-05-21 <![CDATA[ Intra-tumoral delivery of FLT3L with CXCR3/CCR5 ligands promotes XCR1+ DC1 infiltration and activates anti-tumor immunity ]]> https://biorxiv.org/content/10.1101/2025.05.19.654717v1?rss=1 Gorline, L. Rosa do Carmo, F. Bourdely, P. Borneres, J. Vaudiau, N. Semervil, A. Vetillard, M. Ok, A. Fiquet, O. Andrade, M. Theobald, H. Collin, M. Calmette, J. Anselmi, G. Fico, F. Ginhoux, F. Saveanu, L. Helft, J. Dalod, M. Dusseaux, M. Di Santo, J. P. Hugues, S. Guermonprez, P. 2025-05-23 doi:10.1101/2025.05.19.654717 Cold Spring Harbor Laboratory Press 2025-05-23 <![CDATA[ Feeding induces c-Fos in hepatocytes contributing to hepatocellular carcinoma in obesity ]]> https://biorxiv.org/content/10.1101/2025.05.20.654880v1?rss=1 Li, A. Gilglioni, E. H. St-Pierre-Wijckmans, W. Hosseinzadeh, L. Veyrat-Durebex, C. Singh, S. P. Coppari, R. Bakiri, L. Gurzov, E. N. 2025-05-24 doi:10.1101/2025.05.20.654880 Cold Spring Harbor Laboratory Press 2025-05-24 <![CDATA[ Harnessing distinct tissue-resident immune niches via S100A9/TLR4 improves ketone, lipid, and glucose metabolism ]]> https://biorxiv.org/content/10.1101/2025.05.21.655283v1?rss=1 Lucibello, G. Ursino, G. Teixeira, P. D. S. Zahoran, S. Fanuele, F. Kallikourdis, M. Visentin, F. Veyrat-Durebex, C. Widmer, A. Wu, Y. Cremonesi, M. Wollheim, C. B. Castets, P. Ramadori, G. Coppari, R. 2025-05-27 doi:10.1101/2025.05.21.655283 Cold Spring Harbor Laboratory Press 2025-05-27 <![CDATA[ Neurotoxicity of Propylene Glycol Butyl Ether: Multiomic Evidence from Human BrainSpheres ]]> https://biorxiv.org/content/10.1101/2025.05.22.655411v1?rss=1 Lopez Rodriguez, D. Pamies, D. Boccard, J. Meister, I. Galmiche, M. Sajic, T. Maret, E. Heritier, N. Frangiamone, M. Thomas, A. Hopf, N. Rudaz, S. Zurich, M.-G. 2025-05-27 doi:10.1101/2025.05.22.655411 Cold Spring Harbor Laboratory Press 2025-05-27 <![CDATA[ Temporal and spatial coordination of DNA segregation and cell division in an archaeon. ]]> https://biorxiv.org/content/10.1101/2025.05.28.656325v1?rss=1 Parham, J. Cezanne, A. Sorichetti, V. Hoogenberg, B. Foo, S. Kuo, Y.-w. Mawdesley, E. Gatward, L. D. Schulze, U. Boulanger, J. Saric, A. Baum, B. 2025-05-29 doi:10.1101/2025.05.28.656325 Cold Spring Harbor Laboratory Press 2025-05-29 <![CDATA[ The Arch from the Stones: Understanding Protein Folding Energy Landscapes via Bio-inspired Collective Variables ]]> https://biorxiv.org/content/10.1101/2025.05.28.656575v1?rss=1 Rizzi, V. Heritier, M. Piasentin, N. Aureli, S. Gervasio, F. L. 2025-05-30 doi:10.1101/2025.05.28.656575 Cold Spring Harbor Laboratory Press 2025-05-30 <![CDATA[ Aberrant cerebrovascular reactivity presents as an early biomarker of psychosis susceptibility in patients with 22q11.2DS ]]> https://biorxiv.org/content/10.1101/2025.06.02.657392v1?rss=1 Delavari, F. Moia, S. Forrer, S. Sandini, C. Kojovic, N. Pascucci, A. Lacour, C. Eliez, S. Van De Ville, D. 2025-06-03 doi:10.1101/2025.06.02.657392 Cold Spring Harbor Laboratory Press 2025-06-03 <![CDATA[ Oxytocin release modulates acute neuroinflammation and improves brain development after pediatric traumatic brain injury ]]> https://biorxiv.org/content/10.1101/2025.06.02.652172v1?rss=1 Knoop, M. Trak, E. Possovre, M.-L. Van de Looij, Y. Schirmbeck, G. Ceyzeriat, K. Pitetti, J.-L. Farias Sanches, E. Musardo, S. Millet, P. Tsartsalis, S. Tournier, B. B. Bellone, C. Sizonenko, S. V. Jacquens, A. Baud, O. 2025-06-05 doi:10.1101/2025.06.02.652172 Cold Spring Harbor Laboratory Press 2025-06-05 <![CDATA[ Cardiorespiratory mechanisms triggered during music perception in preterm infants and adults ]]> https://biorxiv.org/content/10.1101/2025.06.03.657691v1?rss=1 Lavezzo, L. Barcos-Munoz, F. Benis, D. Margaria, J. Grandjean, D. Scilingo, E. P. Vollenweider, A. Henriot, S. Nardelli, M. Hüppi, P. Filippa, M. 2025-06-07 doi:10.1101/2025.06.03.657691 Cold Spring Harbor Laboratory Press 2025-06-07 <![CDATA[ Development of a liposomal formulation of a TKI: the active loading of erlotinib.HCl ]]> https://biorxiv.org/content/10.1101/2025.06.06.658400v1?rss=1 Schelker, C. Trap, V. Boechard, G. Nowak-Sliwinska, P. 2025-06-07 doi:10.1101/2025.06.06.658400 Cold Spring Harbor Laboratory Press 2025-06-07 <![CDATA[ iSleep: Continuous, binocular pupil tracking in sleep and reduced consciousness for physiological monitoring, predictions and interventions ]]> https://biorxiv.org/content/10.1101/2025.06.13.659058v1?rss=1 Yuzgec, O. Legendre, G. Asadian, A. Gloria, Y. Bayer, L. Tourdot, Q. Pellat, S. Novozhilova, S. D'Ancona, C. Ulanova, M. Kecik, M. Maccari, A. Lopez, D. Licini, L. Nguyen Tang, G. Van Delden, S. Bravetti, G. E. Vo, T. Kropp, M. Boex, C. Jakus, L. Schaller, K. Sollander, F. Vutskits, L. Thumann, G. Schwartz, S. Huber, D. 2025-06-15 doi:10.1101/2025.06.13.659058 Cold Spring Harbor Laboratory Press 2025-06-15 <![CDATA[ Diatom ultrastructural diversity across controlled and natural environments ]]> https://biorxiv.org/content/10.1101/2025.06.16.659906v1?rss=1 Flori, S. Mikus, F. Flaum, E. Moog, K. Guessoum, S. Beavis, T. Zwahlen, S. Romero-Brey, I. Orschot, V. Olivetta, M. Steele-Ogus, M. Yeh, E. Mobile Labs Team, Dudin, O. Schwab, Y. Dey, G. Vincent, F. 2025-06-16 doi:10.1101/2025.06.16.659906 Cold Spring Harbor Laboratory Press 2025-06-16 <![CDATA[ Domain-Specific EPR Spectroscopy to Monitor Facilitated Dissociation of a DNA-Transcription Factor Complex ]]> https://biorxiv.org/content/10.1101/2025.06.13.659481v1?rss=1 Epasto, L. M. Khalil, M. Sicoli, G. Kurzbach, D. 2025-06-17 doi:10.1101/2025.06.13.659481 Cold Spring Harbor Laboratory Press 2025-06-17 <![CDATA[ The Luminal Ring Protein C2CD3 Acts as a Radial In-to-Out Organizer of the Distal Centriole and Appendages ]]> https://biorxiv.org/content/10.1101/2025.06.17.660204v1?rss=1 Bertiaux, E. Louvel, V. McCafferty, C. van den Hoek, H. Batman, U. Mukherjee, S. Bournonville, L. Mercey, O. Mean, I. Mueller, A. Van der Stappen, P. Buss, G. Daraspe, J. Genoud, C. Stearns, T. Engel, B. D. Hamel, V. Guichard, P. 2025-06-18 doi:10.1101/2025.06.17.660204 Cold Spring Harbor Laboratory Press 2025-06-18 <![CDATA[ Monomeric and oligomeric forms of Bcl-xL in direct andindirect inhibition of apoptosis ]]> https://biorxiv.org/content/10.1101/2025.06.16.659449v1?rss=1 Elsner, C. Roderer, D. Bordignon, E. 2025-06-20 doi:10.1101/2025.06.16.659449 Cold Spring Harbor Laboratory Press 2025-06-20 <![CDATA[ Visualizing the Dominant GPCR Coupling of Pathogenic Gαo Mutants in GNAO1-Related Disorders ]]> https://biorxiv.org/content/10.1101/2025.06.19.660437v1?rss=1 Larasati, Y. A. Rabesahala de Meritens, C. Stoeber, M. Katanaev, V. L. Solis, G. P. 2025-06-22 doi:10.1101/2025.06.19.660437 Cold Spring Harbor Laboratory Press 2025-06-22 <![CDATA[ Evolutionarily diverged on-switch for actin assembly in fungal endocytosis ]]> https://biorxiv.org/content/10.1101/2025.06.22.660955v1?rss=1 Sebellin, J. Kandiyoth, F. B. Picco, A. Hakala, M. Rivier-Cordey, A.-S. Michelot, A. Toret, C. P. Kaksonen, M. 2025-06-23 doi:10.1101/2025.06.22.660955 Cold Spring Harbor Laboratory Press 2025-06-23 <![CDATA[ The origins of time: a systematic review of the neural signatures of temporal prediction in infancy ]]> https://biorxiv.org/content/10.1101/2025.06.20.659060v1?rss=1 Rambosson, I. Benis, D. Kabdebon, C. Filippa, M. Grandjean, D. 2025-06-24 doi:10.1101/2025.06.20.659060 Cold Spring Harbor Laboratory Press 2025-06-24 <![CDATA[ MEGaNorm: Normative Modeling of MEG Brain Oscillations Across the Human Lifespan ]]> https://biorxiv.org/content/10.1101/2025.06.23.660997v1?rss=1 Zamanzadeh, M. Verduyn, Y. de Boer, A. A. A. Ros, T. Wolfers, T. Dinga, R. Safar Postma, M. Marquand, A. F. van Wingerden, M. Kia, S. M. 2025-06-25 doi:10.1101/2025.06.23.660997 Cold Spring Harbor Laboratory Press 2025-06-25 <![CDATA[ NLRP1 inflammasome activation in skin equivalents revealsmechanistic insights into the roles of keratinocytes in psoriasis ]]> https://biorxiv.org/content/10.1101/2025.06.25.661501v1?rss=1 Di Filippo, M. Karakaya, T. Cheng, P. Hennig, P. Slaufova, M. Boukamp, P. Pascolo, S. Maul, J. T. Kolm, I. Levesque, M. Kuendig, T. Beer, H.-D. 2025-06-27 doi:10.1101/2025.06.25.661501 Cold Spring Harbor Laboratory Press 2025-06-27 <![CDATA[ Force patterning drives cell flows and 3D spatial order in auditory epithelia ]]> https://biorxiv.org/content/10.1101/2025.06.26.661757v1?rss=1 Weninger, J. Prakash, A. Raman, S. Ladher, R. K. Rao, M. Kruse, K. 2025-06-28 doi:10.1101/2025.06.26.661757 Cold Spring Harbor Laboratory Press 2025-06-28 <![CDATA[ Cardiac-locked auditory stimulation modulates pupil and neural dynamics ]]> https://biorxiv.org/content/10.1101/2025.06.26.661871v1?rss=1 Chiarion, G. Cataldi, J. Schwartz, S. Pelentritou, A. De Lucia, M. 2025-06-28 doi:10.1101/2025.06.26.661871 Cold Spring Harbor Laboratory Press 2025-06-28 <![CDATA[ All You Need Is Water: Converging Ligand Binding Simulations with Hydration Collective Variables ]]> https://biorxiv.org/content/10.1101/2025.06.27.661893v1?rss=1 Schulze, M. Khakhula, T. Piasentin, N. Aureli, S. Rizzi, V. Gervasio, F. L. 2025-07-01 doi:10.1101/2025.06.27.661893 Cold Spring Harbor Laboratory Press 2025-07-01 <![CDATA[ A global genetic interaction map of a human cell reveals conserved principles of genetic networks ]]> https://biorxiv.org/content/10.1101/2025.06.30.662193v1?rss=1 Billmann, M. Costanzo, M. Zhang, X. Hassan, A. Z. Rahman, M. Brown, K. R. Chan, K. S. Tong, A. H. Pons, C. Ward, H. N. Ross, C. van Leeuwen, J. Aregger, M. Lawson, K. A. Mair, B. Roth, A. F. Sen, N. E. Forster, D. T. Tan, G. Merro, P. Masud, S. N. Lee, Y. Aguilera-Uribe, M. Usaj, M. Almeida, S. M. Aulakh, K. Bhojoo, U. Birkadze, S. Budijono, N. Cai, X. Caumanns, J. J. Chandrashekhar, M. Chang, D. Clinie, R. Dasgupta, K. Drazic, A. Rojas Echenique, J. I. Gacesa, R. Granda Farias, A. Habsid, A. Horecka, I. Kantautas, K. Ji, F. Kim, D.-K. Lee, S. Y. Li 2025-07-02 doi:10.1101/2025.06.30.662193 Cold Spring Harbor Laboratory Press 2025-07-02 <![CDATA[ Warm-loving species perform well under limiting resources:trait combinations for future climate ]]> https://biorxiv.org/content/10.1101/2025.07.04.662912v1?rss=1 Levasseur, S. A. Y. Weber de Melo, V. Hille Ris Lambers, J. Klausmeier, C. A. Kremer, C. T. Litchman, E. Reyes, M. Thomas, M. K. Narwani, A. 2025-07-07 doi:10.1101/2025.07.04.662912 Cold Spring Harbor Laboratory Press 2025-07-07 <![CDATA[ Shedding of mitochondrial Voltage-Dependent Anion Channel-1 (VDAC1) Reflects COVID-19 Severity and Reveals Macrophage Dysfunction ]]> https://biorxiv.org/content/10.1101/2025.07.07.663218v1?rss=1 Sjogren, M. Duner, P. De Marinis, Y. Neumann, A. Leandersson, K. Rasmussen, M. Wollheim, C. B. Salehi, A. 2025-07-08 doi:10.1101/2025.07.07.663218 Cold Spring Harbor Laboratory Press 2025-07-08 <![CDATA[ Spatial tumour-immune ecosystems shape the efficacy of anti-PD1 immunotherapy in primary cutaneous melanoma ]]> https://biorxiv.org/content/10.1101/2025.07.07.661465v1?rss=1 Pham, F. Dufeu, M. Benboubker, V. Grimont, M. LHORISSON, A. Berthet, J. Donzel, M. Schneider, R. Tonon, L. Doffin, A.-C. Boivin, F. Durand, S. Dubois, B. Lopez, J. Caux, C. Valladeau-Guilemond, J. Eberhardt, A. Dalle, S. CARAMEL, J. 2025-07-10 doi:10.1101/2025.07.07.661465 Cold Spring Harbor Laboratory Press 2025-07-10 <![CDATA[ Motor Cortex Modulates Ipsilateral Limb Movement Through a Direct Cortico-Cerebellar Circuit ]]> https://biorxiv.org/content/10.1101/2025.07.08.663625v1?rss=1 Schaefer, C. B. Oliveira Silva, R. Hasanbegovic, H. Adolfs, Y. Pasterkamp, J. Li, X. Li, A. Gong, H. De Zeeuw, C. Hoebeek, F. Gao, Z. 2025-07-11 doi:10.1101/2025.07.08.663625 Cold Spring Harbor Laboratory Press 2025-07-11 <![CDATA[ The molecular basis of tricalbin-mediated membrane contact site organization in cells ]]> https://biorxiv.org/content/10.1101/2025.07.11.664157v1?rss=1 Ivanovic, L. Boinet, A.-L. Picco, A. Kaksonen, M. Kukulski, W. 2025-07-11 doi:10.1101/2025.07.11.664157 Cold Spring Harbor Laboratory Press 2025-07-11 <![CDATA[ High Throughput Information Extraction of Printed Specimen Labels from Large-Scale Digitization of Entomological Collections using a Semi-Automated Pipeline ]]> https://biorxiv.org/content/10.1101/2025.07.09.663724v1?rss=1 Belot, M. Tuberosa, J. Preuss, L. Svezhentseva, O. Claessen, M. Bölling, C. Schuster, F. Leger, T. 2025-07-12 doi:10.1101/2025.07.09.663724 Cold Spring Harbor Laboratory Press 2025-07-12 <![CDATA[ Conservation and divergence of UVR8-COP1/SPA-HY5 signaling in UV-B responses of Marchantia polymorpha ]]> https://biorxiv.org/content/10.1101/2025.07.16.665153v1?rss=1 Liang, Y. Podolec, R. Chappuis, R. Defossez, E. Glauser, G. Rötzer, J. Stolze, S. C. Dolan, L. Nakagami, H. Demarsy, E. Ulm, R. 2025-07-17 doi:10.1101/2025.07.16.665153 Cold Spring Harbor Laboratory Press 2025-07-17 <![CDATA[ Sub-Nanomolar Detection and Discrimination of Microcystin Congeners Using Aerolysin Nanopores ]]> https://biorxiv.org/content/10.1101/2025.07.15.664886v1?rss=1 Agerova, A. Bada Juarez, J. F. Abriata, L. Marcaida, M. J. Carratala, A. Janssen, E. Cao, C. Kohn, T. Dal Peraro, M. 2025-07-18 doi:10.1101/2025.07.15.664886 Cold Spring Harbor Laboratory Press 2025-07-18 <![CDATA[ A single-cell transcriptomic atlas maps cerebellar astrocyte diversity and uncovers the transcriptional code underlying their maturation trajectories ]]> https://biorxiv.org/content/10.1101/2025.07.17.665323v1?rss=1 Cerrato, V. Turrini, G. Vitali, I. Xiong, B. Solanelles-Farre, L. Lopes, A. Magrinelli, E. Bocchi, R. Götz, M. Fischer-Sternjak, J. Boda, E. Buffo, A. Telley, L. 2025-07-22 doi:10.1101/2025.07.17.665323 Cold Spring Harbor Laboratory Press 2025-07-22 <![CDATA[ Early lineage divergence segregates sensory and non-sensory thalamic circuits ]]> https://biorxiv.org/content/10.1101/2025.07.17.665342v1?rss=1 Puche-Aroca, L. Andres-Bayon, B. Wilson, E. S. Javed, A. Torregrosa-Mira, A. Lopez-Atalaya, J. P. Lopez-Bendito, G. 2025-07-22 doi:10.1101/2025.07.17.665342 Cold Spring Harbor Laboratory Press 2025-07-22 <![CDATA[ Direction-selective retinal ganglion cells encode motion direction uniformly, despite having discretely distributed cardinal preferences ]]> https://biorxiv.org/content/10.1101/2025.07.23.666360v1?rss=1 Paris, C. Hubert, F. Franke, F. Marre, O. Chalk, M. Ferrari, U. 2025-07-28 doi:10.1101/2025.07.23.666360 Cold Spring Harbor Laboratory Press 2025-07-28 <![CDATA[ Tubulin autoregulation tunes microtubule dynamics to support multicellular architecture and viability ]]> https://biorxiv.org/content/10.1101/2025.07.28.667019v1?rss=1 Almeida, A. C. Lacheheub, C. Gasic, I. 2025-07-30 doi:10.1101/2025.07.28.667019 Cold Spring Harbor Laboratory Press 2025-07-30 <![CDATA[ A sensitive orange fluorescent calcium ion indicator for imaging neural activity ]]> https://biorxiv.org/content/10.1101/2025.07.28.667269v1?rss=1 Aggarwal, A. Baker, H. A. Durst, C. D. Chen, I.-W. de Chambrier, P. Gonzales, J. M. Marvin, J. S. Vandal, M. Lundberg, T. Sakoi, K. Patel, R. H. Wang, C.-Y. Visser, F. Fouad, Y. Sunil, S. Wiens, M. Terai, T. Takahashi-Yamashiro, K. Thompson, R. J. Brown, T. A. Nasu, Y. Nguyen, M. D. Gordon, G. R. J. McFarlane, S. Podgorski, K. Holtmaat, A. Campbell, R. E. Lohman, A. W. 2025-07-31 doi:10.1101/2025.07.28.667269 Cold Spring Harbor Laboratory Press 2025-07-31 <![CDATA[ Drosophila Video-assisted Activity Monitor (DrosoVAM): a versatile method for behavior monitoring ]]> https://biorxiv.org/content/10.1101/2025.07.29.667363v1?rss=1 Revel, M. Nagoshi, E. Maeda, R. K. 2025-07-31 doi:10.1101/2025.07.29.667363 Cold Spring Harbor Laboratory Press 2025-07-31 <![CDATA[ Native Ion Mobility-MS Reveals the Bead Ejection Mechanism in Multi-Domain Nucleic Acids ]]> https://biorxiv.org/content/10.1101/2025.07.29.667413v1?rss=1 View larger version (37K): org.highwire.dtl.DTLVardef@42d7c3org.highwire.dtl.DTLVardef@63445dorg.highwire.dtl.DTLVardef@11d7056org.highwire.dtl.DTLVardef@1ba48bb_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Ghosh, D. Rosu, F. Gabelica, V. 2025-08-01 doi:10.1101/2025.07.29.667413 Cold Spring Harbor Laboratory Press 2025-08-01 <![CDATA[ Regional BOLD variability reflects microstructural maturation and neuronal ensheathment in the preterm infant cortex ]]> https://biorxiv.org/content/10.1101/2025.07.30.667792v1?rss=1 Sa de Almeida, J. Boehringer, A. Loukas, S. Fischi-Gomez, E. Van Der Veek, A. Lordier, L. Courvoisier, S. Lazeyras, F. Van De Ville, D. Ball, G. Huppi, P. S. 2025-08-01 doi:10.1101/2025.07.30.667792 Cold Spring Harbor Laboratory Press 2025-08-01 <![CDATA[ Characterization of the Post-Mating Responses of Drosophila hydei, a species that lacks Sex-Peptide. ]]> https://biorxiv.org/content/10.1101/2025.07.31.667665v1?rss=1 Revel, M. Yildirim, Z. Fabbro, L. Nagoshi, E. Maeda, R. K. 2025-08-02 doi:10.1101/2025.07.31.667665 Cold Spring Harbor Laboratory Press 2025-08-02 <![CDATA[ CDK4 Restricts Triple-Negative Breast Cancer Cell Migration via Phosphorylation-Driven Activation of Myo9b RhoGAP Function ]]> https://biorxiv.org/content/10.1101/2025.08.06.668850v1?rss=1 Parashar, K. Simo Riudalbas, L. Ravera, A. Prieto Banos, S. Moi, D. Drake, B. F. Shi, J. Geller, S. Dessimoz, C. Fantner, G. E. Ziegler, D. V. Fajas, L. 2025-08-08 doi:10.1101/2025.08.06.668850 Cold Spring Harbor Laboratory Press 2025-08-08 <![CDATA[ A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases ]]> https://biorxiv.org/content/10.1101/2025.08.08.669299v1?rss=1 Caregnato, A. Chen, H. Kvasnica, M. Hohmann, U. Oklestkova, J. Ferrer, K. Broger, L. Hothorn, L. A. Strnad, M. Hothorn, M. 2025-08-09 doi:10.1101/2025.08.08.669299 Cold Spring Harbor Laboratory Press 2025-08-09 <![CDATA[ High-salt diet modulates endocrine regulation between cortisol and FGF23 ]]> https://biorxiv.org/content/10.1101/2025.08.14.670453v1?rss=1 Moor, M. Kopper, K. Pechere-Bertschi, A. Sagmeister, M. S. Hardy, R. Feraille, E. Fuster, D. G. Loffing, J. Pathare, G. 2025-08-20 doi:10.1101/2025.08.14.670453 Cold Spring Harbor Laboratory Press 2025-08-20 <![CDATA[ Adaptation of Enterococcus faecalis to intestinal mucus revealed by a human colonic organoid model ]]> https://biorxiv.org/content/10.1101/2025.08.20.670035v1?rss=1 Mikhaleva, S. Hsiao, P.-L. Kurmashev, A. Anderson, C. M. Colomer-Winter, C. Boos, J. A. Choo, P. Y. Willett, J. L. E. Hierlemann, A. Kline, K. A. Persat, A. 2025-08-20 doi:10.1101/2025.08.20.670035 Cold Spring Harbor Laboratory Press 2025-08-20 <![CDATA[ Temporal Interference Stimulation Enhances Neural Regeneration ]]> https://biorxiv.org/content/10.1101/2025.08.18.670811v1?rss=1 View larger version (49K): org.highwire.dtl.DTLVardef@984165org.highwire.dtl.DTLVardef@1ed8bbdorg.highwire.dtl.DTLVardef@715057org.highwire.dtl.DTLVardef@151882f_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Peressotti, S. Garcia Garrido, M. Dzialecka, P. Law, R. M. H. Portillo Lara, R. Geary, B. Faillace, E. Wojewska, M. Otero-Jimenez, M. Genta, M. Tan, L. Duff, K. Alegre-Abarrategui, J. Green, R. A. Grossman, N. 2025-08-22 doi:10.1101/2025.08.18.670811 Cold Spring Harbor Laboratory Press 2025-08-22 <![CDATA[ Long Non-Coding RNAs in Response to Ebola Virus Vaccine-Induced Immunity ]]> https://biorxiv.org/content/10.1101/2025.08.19.671152v1?rss=1 View larger version (27K): org.highwire.dtl.DTLVardef@25581aorg.highwire.dtl.DTLVardef@1bb31cforg.highwire.dtl.DTLVardef@c3299eorg.highwire.dtl.DTLVardef@e176b9_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Mamede, I. Luscher-Dias, T. Moscardini, I. F. Gonzalez, P. Marinho, B. Marcon, F. Hirata, T. D. C. VSV-EBOPLUS Consortium, Eichberg, M. Medaglini, D. Harandi, A. M. Siegrist, C. A. Ottenhoff, T. H. M. Santoro, F. Goncalves, A. N. A. Polidoro, R. Franco, G. R. Amaral, P. P. Nakaya, H. 2025-08-23 doi:10.1101/2025.08.19.671152 Cold Spring Harbor Laboratory Press 2025-08-23 <![CDATA[ HAK-actin, U-ExM-compatible probe to image the actin cytoskeleton ]]> https://biorxiv.org/content/10.1101/2025.08.26.672318v1?rss=1 Mercey, O. Reymond, L. Lemaitre, F. Mean, I. Laporte, M. Olivetta, M. Sadoul, K. Dudin, O. HAMEL, V. Guichard, P. 2025-08-27 doi:10.1101/2025.08.26.672318 Cold Spring Harbor Laboratory Press 2025-08-27 <![CDATA[ Balanced contractility and adhesion drive polarization in a minimal elastic actomyosin network ]]> https://biorxiv.org/content/10.1101/2025.08.26.672435v1?rss=1 Messi, Z. Raynaud, F. Goehring, N. W. Verkhovsky, A. B. 2025-08-29 doi:10.1101/2025.08.26.672435 Cold Spring Harbor Laboratory Press 2025-08-29 <![CDATA[ Circadian control of dopaminergic signaling to the mushroom body regulates sleep through rhythmic Pka-C1 transcription in Drosophila ]]> https://biorxiv.org/content/10.1101/2025.08.29.673050v1?rss=1 Lago Solis, B. Nagoshi, E. 2025-08-31 doi:10.1101/2025.08.29.673050 Cold Spring Harbor Laboratory Press 2025-08-31 <![CDATA[ Structural and dynamic basis of indirect apoptosis inhibition by Bcl-xL: a case study with Bid ]]> https://biorxiv.org/content/10.1101/2025.08.31.673340v1?rss=1 Elsner, C. Hanke, A. Vadas, O. Gervasio, F. L. Bordignon, E. 2025-09-04 doi:10.1101/2025.08.31.673340 Cold Spring Harbor Laboratory Press 2025-09-04 <![CDATA[ Lysosome-Dependent Sphingolipid Regulation as a potential therapeutic Target for Cohen Syndrome ]]> https://biorxiv.org/content/10.1101/2025.09.04.674037v1?rss=1 Vacca, F. Prasad, R. Barakullah, H. Da Costa, R. Vossio, S. Moreau, D. Sun, W. Riezman, H. Ansar, M. 2025-09-04 doi:10.1101/2025.09.04.674037 Cold Spring Harbor Laboratory Press 2025-09-04 <![CDATA[ A Modular Chromosomal Passenger Complex Rewires Chromosome Segregation in Plasmodium berghei ]]> https://biorxiv.org/content/10.1101/2025.09.05.674402v1?rss=1 Roques, M. Niu, C. Brochet, M. Brusini, L. A. 2025-09-05 doi:10.1101/2025.09.05.674402 Cold Spring Harbor Laboratory Press 2025-09-05 <![CDATA[ Anti-PD-1/PD-L1 Therapy Triggers Cognitive Deficits and Anxiety-Like Behaviors Through Tumor-Initiated Neuroinflammatory Niches in Male Mice ]]> https://biorxiv.org/content/10.1101/2025.09.03.673981v1?rss=1 Nicola, C. Pedard, M. Dubois, M. Desrues, L. Neveu, P. Riou, G. Johnston, I. Dembele, P. K. Lecras, P. Vaudry, D. Adriouch, S. Joly, F. Hilber, P. Wurtz, O. Castel, H. 2025-09-07 doi:10.1101/2025.09.03.673981 Cold Spring Harbor Laboratory Press 2025-09-07 <![CDATA[ Transcriptomic and proteomic analysis of quiescent epimastigotes as a resource for investigating Trypanosoma cruzi persistence. ]]> https://biorxiv.org/content/10.1101/2025.09.09.675056v1?rss=1 Olmo, F. Hesketh, A. Hage, H. Monneuse, J.-M. Taylor, M. C. Costa, F. C. DaSilva, C. Bequet, F. Escudie, F. Mercer, D. Saliou, A. Chatelain, E. Kelly, J. M. Abi Ghanem, J. 2025-09-09 doi:10.1101/2025.09.09.675056 Cold Spring Harbor Laboratory Press 2025-09-09 <![CDATA[ Microtubule lattice conformation and integrity regulate α-tubulin acetylation ]]> https://biorxiv.org/content/10.1101/2025.09.09.675099v1?rss=1 Aumeier, C. Egoldt, C. Tran, J. Velluz, M.-C. 2025-09-10 doi:10.1101/2025.09.09.675099 Cold Spring Harbor Laboratory Press 2025-09-10 <![CDATA[ Altered Use of Prior Expectations and Modified Neural Dynamics in a Mouse Model of Autism ]]> https://biorxiv.org/content/10.1101/2025.09.12.675910v1?rss=1 Davatolhagh, M. F. Couto, J. P. Melin, M. Oesch, L. T. Findling, C. Morales, P. Hong, I. Laboratory, I. B. Churchland, A. K. 2025-09-13 doi:10.1101/2025.09.12.675910 Cold Spring Harbor Laboratory Press 2025-09-13 <![CDATA[ GPT-4 accurately predicts human emotions and their neural correlates ]]> https://biorxiv.org/content/10.1101/2025.09.18.677029v1?rss=1 Santavirta, S. Suominen, L. Wu, Y. Sander, D. Nummenmaa, L. 2025-09-19 doi:10.1101/2025.09.18.677029 Cold Spring Harbor Laboratory Press 2025-09-19 <![CDATA[ Sensitivity of the human temporal voice areas to nonhuman primate vocalizations ]]> https://biorxiv.org/content/10.1101/2025.09.19.677258v1?rss=1 Ceravolo, L. Debracque, C. Gruber, T. Grandjean, D. 2025-09-19 doi:10.1101/2025.09.19.677258 Cold Spring Harbor Laboratory Press 2025-09-19 <![CDATA[ Evolutionary history and recurrent host adaptation in ancient Salmonella enterica ]]> https://biorxiv.org/content/10.1101/2025.09.18.676881v1?rss=1 Jackson, I. Neumann, G. U. Mayr, A.-T. Andrades Valtuena, A. Hiss, A. N. Musralina, L. Alt, K. W. Beisenov, A. Bejko, L. Berezina, N. Berner, M. Bhattacharya, A. Binder, M. Bitadze, L. Bondar, M. Bretos, M. Bruyako, I. Bugarski, I. Buzhilova, A. Charami, A. Daly, K. Desideri, J. Diaz-Zorita Bonilla, M. Djansugurova, L. Rosselet-Christ, D. Doumani Dupuy, P. Eggers, S. Ellingvag, S. Ernee, M. Furmanek, M. Furtwängler, A. Gerber, D. Gimeno Martinez, B. Haas-Gebhard, B. Hałuszko, A. Harbeck, M. Heilmann, D. Ivanisevic, V. Jia, X. Karapetian, M. Keller, M. 2025-09-20 doi:10.1101/2025.09.18.676881 Cold Spring Harbor Laboratory Press 2025-09-20 <![CDATA[ Strontium treatment potentiates bone anabolic action of intermittent PTH in ovariectomized rats ]]> https://biorxiv.org/content/10.1101/2025.09.18.677152v1?rss=1 Thouverey, C. Badoud, I. Ammann, P. 2025-09-21 doi:10.1101/2025.09.18.677152 Cold Spring Harbor Laboratory Press 2025-09-21 <![CDATA[ A Novel Zebrafish Luminescent Biosensor for Kidney Tubulopathy, Metal Toxicity, and Drug Screening ]]> https://biorxiv.org/content/10.1101/2025.09.19.677027v1?rss=1 Lai, H. Goldade, M. Keller, S. A. Worms, I. Luciani, A. Neuhauss, S. C. F. Slaveykova, V. I. Devuyst, O. Chen, Z. 2025-09-21 doi:10.1101/2025.09.19.677027 Cold Spring Harbor Laboratory Press 2025-09-21 <![CDATA[ The zebrafish model tackles anti-P2Y12 variability in humans: a translational approach ]]> https://biorxiv.org/content/10.1101/2025.09.21.676872v1?rss=1 Ciepla, P. Fish, R. J. Nolli, S. Dunoyer-Geindre, S. Charlon-Gay, J. Reny, J.-L. Neerman-Arbez, M. Fontana, P. 2025-09-21 doi:10.1101/2025.09.21.676872 Cold Spring Harbor Laboratory Press 2025-09-21 <![CDATA[ Inhibition of 3-mercaptopyruvate sulfurtransferase enhances CD8⁺ T-cell antitumor immunity ]]> https://biorxiv.org/content/10.1101/2025.09.22.675323v1?rss=1 Urwyler, M. Korsos, M. Dupuychaffray, E. Ascencao, K. Petrosino, M. Zuhra, K. Tachet, J. Purwar, P. Alvarez, M. Pommier, A. Gad, M. Abdelkader, R. Szabo, C. Bourquin, C. 2025-09-23 doi:10.1101/2025.09.22.675323 Cold Spring Harbor Laboratory Press 2025-09-23 <![CDATA[ Fluorescence lifetime estimation: a practical approach using Flipper-TR FLIM ]]> https://biorxiv.org/content/10.1101/2025.09.23.678124v1?rss=1 Mandal, T. Roux, A. Garcia-Arcos, J. M. 2025-09-25 doi:10.1101/2025.09.23.678124 Cold Spring Harbor Laboratory Press 2025-09-25 <![CDATA[ Ovarian development is driven by early spatiotemporal priming of the coelomic epithelium ]]> https://biorxiv.org/content/10.1101/2025.09.24.678234v1?rss=1 Djari, c. MAYERE, C. Guy, M. Gomez, A. P. Barreau, P. Rozier, A. Martinez, A. Gibson, T. Guerin, C. Ademi, H. Wilhelm, D. McKey, J. Chaboissier, M.-C. nef, s. 2025-09-25 doi:10.1101/2025.09.24.678234 Cold Spring Harbor Laboratory Press 2025-09-25 <![CDATA[ Negative feedback regulation of the hemi-arrestin MAPK scaffold Sms1 prevents untimely mating ]]> https://biorxiv.org/content/10.1101/2025.09.24.678297v1?rss=1 Sieber, B. Merlini, L. Li, W. Besomi, M. Michon, L. Gordon-Lennox, S. Martin, S. G. 2025-09-25 doi:10.1101/2025.09.24.678297 Cold Spring Harbor Laboratory Press 2025-09-25 <![CDATA[ Bora, CEP192 and Cenexin activate different Plk1 pools and regulate distinct cell and centrosome cycle transitions ]]> https://biorxiv.org/content/10.1101/2025.09.30.679461v1?rss=1 Dwivedi, D. Borges, C. Harry, D. Cirillo, L. Meraldi, P. 2025-09-30 doi:10.1101/2025.09.30.679461 Cold Spring Harbor Laboratory Press 2025-09-30 <![CDATA[ Translating Music to Touch: Exploring Tactile Perception of Pitch, Roughness, and Pleasantness ]]> https://biorxiv.org/content/10.1101/2025.09.30.679532v1?rss=1 Marozeau, J. Taylor, A. Novozhilova, S. Prsa, M. Huber, D. 2025-10-01 doi:10.1101/2025.09.30.679532 Cold Spring Harbor Laboratory Press 2025-10-01 <![CDATA[ Lipid Landscape of human cells ]]> https://biorxiv.org/content/10.1101/2025.10.05.680593v1?rss=1 Foged, M. M. Clemmensen, K. K. B. Holland, L. K. K. Giacobini, J. D. Bilgin, M. Titeca, K. Gavin, A.-C. Jaattela, M. Maeda, K. 2025-10-06 doi:10.1101/2025.10.05.680593 Cold Spring Harbor Laboratory Press 2025-10-06 <![CDATA[ Acoustic Features of Emotional Expression in Preverbal Infant Vocalizations ]]> https://biorxiv.org/content/10.1101/2025.10.06.680673v1?rss=1 Mauchand, M. Lorenzini, I. Gratier, M. Gomes-Fernandes, A. Pugin, L. Grandjean, D. Filippa, M. 2025-10-06 doi:10.1101/2025.10.06.680673 Cold Spring Harbor Laboratory Press 2025-10-06 <![CDATA[ Return of the GEDAI: Unsupervised EEG Denoising based on Leadfield Filtering ]]> https://biorxiv.org/content/10.1101/2025.10.04.680449v1?rss=1 Ros, T. Ferat, V. Huang, Y. Colangelo, C. Kia, S. M. Wolfers, T. Vulliemoz, S. Michela, A. 2025-10-07 doi:10.1101/2025.10.04.680449 Cold Spring Harbor Laboratory Press 2025-10-07 <![CDATA[ Reversing Nicotine Toxicity: how Platelet-Rich Plasma Enhances Cell Recovery through Autophagy Modulation ]]> https://biorxiv.org/content/10.1101/2025.10.06.680686v1?rss=1 Veriepe-Salerno, J. Cancela, J. Vischer, S. Turzi, A. Cuendet, M. Giannopoulou, C. Berndt, S. 2025-10-07 doi:10.1101/2025.10.06.680686 Cold Spring Harbor Laboratory Press 2025-10-07 <![CDATA[ Generation of apical-out nasal organoids to facilitate viral infection and drug screening ]]> https://biorxiv.org/content/10.1101/2025.10.07.680885v1?rss=1 Stroulios, G. Hubert, M. Chang, W. Eaves, A. Louis, S. Kramer, P. Tapparel, C. Simmini, S. 2025-10-07 doi:10.1101/2025.10.07.680885 Cold Spring Harbor Laboratory Press 2025-10-07 <![CDATA[ Co-encapsulated liposomal formulations of tubacin and erlotinib.HCl: a comprehensive stability strategy ]]> https://biorxiv.org/content/10.1101/2025.10.08.681158v1?rss=1 Schelker, C. Monteiro, C. Borchard, G. Nowak-Sliwinska, P. 2025-10-08 doi:10.1101/2025.10.08.681158 Cold Spring Harbor Laboratory Press 2025-10-08 <![CDATA[ Lineage of origin-specific developmental programs drive the behaviors of malignant cells in an avian embryo model of human Medulloblastoma subgroups ]]> https://biorxiv.org/content/10.1101/2025.10.09.681440v1?rss=1 MALLET, M. MARTIN, F. THOINET, K. IMBERT, C. SARHADI, M. GANOFSKY, J. TORREJON DIAZ, J. FENOUIL, T. DELLOYE-BOURGEOIS, C. FALK, J. FAURE-CONTER, C. TELLEY, L. MEYRONET, D. AYRAULT, O. CASTELLANI, V. TAUSZIG-DELAMASURE, S. 2025-10-10 doi:10.1101/2025.10.09.681440 Cold Spring Harbor Laboratory Press 2025-10-10 <![CDATA[ NATO3 protects dopaminergic neurons in mouse in vivo and human in vitro Parkinson's disease models ]]> https://biorxiv.org/content/10.1101/2025.10.10.681573v1?rss=1 Valencia-Alarcon, E. P. Duret, L. C. Kobayashi, E. Cattaneo, O. Schneider, B. L. Nagoshi, E. 2025-10-10 doi:10.1101/2025.10.10.681573 Cold Spring Harbor Laboratory Press 2025-10-10 <![CDATA[ Temporal evolution of Neural Codes: The Added Value of a Geometric Approach to Linear Coefficients ]]> https://biorxiv.org/content/10.1101/2025.10.10.681582v1?rss=1 View larger version (19K): org.highwire.dtl.DTLVardef@c1584forg.highwire.dtl.DTLVardef@18cdd30org.highwire.dtl.DTLVardef@10d7c22org.highwire.dtl.DTLVardef@50a6fa_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Desbordes, T. Olasagasti, I. Piron, N. Schwartz, S. Kazanina, N. 2025-10-10 doi:10.1101/2025.10.10.681582 Cold Spring Harbor Laboratory Press 2025-10-10 <![CDATA[ Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues ]]> https://biorxiv.org/content/10.1101/2025.10.12.681824v1?rss=1 View larger version (58K): org.highwire.dtl.DTLVardef@18b39f3org.highwire.dtl.DTLVardef@1898670org.highwire.dtl.DTLVardef@1d95517org.highwire.dtl.DTLVardef@1615f14_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Ng, K. Sebaa, H. Hirani, N. Chizh, A. Messi, Z. Bland, T. Sugioka, K. Goehring, N. W. 2025-10-13 doi:10.1101/2025.10.12.681824 Cold Spring Harbor Laboratory Press 2025-10-13 <![CDATA[ Tanycytic annexinA1-containing extracellular vesicles control thermogenesis by orchestrating microglial and neuronal functions. ]]> https://biorxiv.org/content/10.1101/2025.10.12.681867v1?rss=1 Dali, R. Lopez-Rodriguez, D. Kolotuev, I. Gavini, C. Deglise, T. Di Valentin, E. Rohrbach, A. Buchs, J. Estrada-Meza, J. Mansuy-Aubert, V. Langlet, F. 2025-10-14 doi:10.1101/2025.10.12.681867 Cold Spring Harbor Laboratory Press 2025-10-14 <![CDATA[ The origin and molecular evolution of the mammalian liver cell architecture ]]> https://biorxiv.org/content/10.1101/2025.10.14.682049v1?rss=1 Yuan, X. Rodriguez-Montes, L. Zaremba, B. Trost, N. Schneider, C. Schmidt, J. Berki, B. Ibberson, D. Leushkin, E. Nickel, B. Palkovits, M. Truman, R. W. Barsh, G. Lees, J. Fallahshahroudi, A. Grützner, F. Tzika, A. C. Milinkovitch, M. C. Pääbo, S. Cardoso-Moreira, M. Kaessmann, H. 2025-10-14 doi:10.1101/2025.10.14.682049 Cold Spring Harbor Laboratory Press 2025-10-14 <![CDATA[ Quantification of Human DNA from Century-Old Archived FFPE Samples for Retrospective Genomic Studies ]]> https://biorxiv.org/content/10.1101/2025.10.17.681771v1?rss=1 Zvenigorosky, V. Gonzalez, A. Broisin, L. Fausser, J.-L. Jeanjean, N. Hluszko Pontet, A. Cannet, C. Lamy, C. M. Keyser, C. Bonah, C. 2025-10-17 doi:10.1101/2025.10.17.681771 Cold Spring Harbor Laboratory Press 2025-10-17 <![CDATA[ Social Perspectives on Larvicide-Based Mosquito Control in Urban Quebec ]]> https://biorxiv.org/content/10.1101/2025.10.20.683413v1?rss=1 Sotelo, F. Levesque, A. Larouche, M. Dupras, J. Turgeon, K. 2025-10-22 doi:10.1101/2025.10.20.683413 Cold Spring Harbor Laboratory Press 2025-10-22 <![CDATA[ The RNA helicase eIF4A as a novel target in insect cells to combat arboviral infections ]]> https://biorxiv.org/content/10.1101/2025.10.22.683850v1?rss=1 Rehling, T. Mentchen, K. Konopka, L. Obermann, W. Weber, F. Schmerer, P. Schetelig, M. Gruenweller, A. Haecker, I. Magari, F. 2025-10-25 doi:10.1101/2025.10.22.683850 Cold Spring Harbor Laboratory Press 2025-10-25 <![CDATA[ Dimer asymmetry in signaling of blue-light sensor histidine kinases ]]> https://biorxiv.org/content/10.1101/2025.10.24.684451v1?rss=1 Arinkin, V. Stadler, A. M. Meier, S. S. M. Jaeger, K.-E. Moeglich, A. Krauss, U. Batra-Safferling, R. 2025-10-26 doi:10.1101/2025.10.24.684451 Cold Spring Harbor Laboratory Press 2025-10-26 <![CDATA[ A bioluminescence-based chemical screen identifies a bactericidal naphthalene scaffold targeting MmpL3 in Mycobacterium abscessus ]]> https://biorxiv.org/content/10.1101/2025.10.26.684512v1?rss=1 Singh, S. Sorayah, R. Chen, Y. Mulholland, C. V. Daher, W. Pee, C. J. E. Casandra, T. A. Z. Wee, D. Oehlers, S. H. Kline, K. A. Chng, S. S. Berney, M. Kremer, L. Moraski, G. Pethe, K. 2025-10-26 doi:10.1101/2025.10.26.684512 Cold Spring Harbor Laboratory Press 2025-10-26 <![CDATA[ CRISPR screen identifies CNIH1 as a selective driver of GPCR export ]]> https://biorxiv.org/content/10.1101/2025.10.27.684930v1?rss=1 Assoumou, K. Drugachenok, P. Arrate, I. M. Zhang, X. Braun, S. M. G. Stoeber, M. 2025-10-28 doi:10.1101/2025.10.27.684930 Cold Spring Harbor Laboratory Press 2025-10-28 <![CDATA[ Non-invasive prediction of conduction velocities in the human brain from MRI-derived microstructure features at 7 Tesla ]]> https://biorxiv.org/content/10.1101/2025.10.28.685017v1?rss=1 Asadi, S. Spencer, A. P. C. Aleman-Gomez, Y. Jedynak, M. Canales-Rodriguez, E. J. Pavan, T. Mullier, E. de Wouters, L. Rigoni, I. Lajous, H. Chan, C. H. M. Cionca, A. Van De Ville, D. Vulliemoz, S. David, O. Hagmann, P. Jelescu, I. O. 2025-10-29 doi:10.1101/2025.10.28.685017 Cold Spring Harbor Laboratory Press 2025-10-29 <![CDATA[ Microtubule deacetylation drives kinesin-1 mediated mitochondrial transport accelerating breast cancer cell migration ]]> https://biorxiv.org/content/10.1101/2025.10.29.685374v1?rss=1 Morin, M. Rodrigues-Ferreira, S. Seiler, C. Ouni, E. Mazaud, D. Moindjie, H. Pous, C. Aumeier, C. Schauer, K. Nahmias, C. 2025-10-30 doi:10.1101/2025.10.29.685374 Cold Spring Harbor Laboratory Press 2025-10-30 <![CDATA[ TimeFlow 2: an unsupervised cell lineage detection method for flow cytometry data ]]> https://biorxiv.org/content/10.1101/2025.11.01.685988v1?rss=1 Liarou, M. Matthes, T. Marchand-Maillet, S. 2025-11-03 doi:10.1101/2025.11.01.685988 Cold Spring Harbor Laboratory Press 2025-11-03 <![CDATA[ Genotype-level quality control substantially reduces error rates in population-scale whole-genome sequencing ]]> https://biorxiv.org/content/10.1101/2025.11.06.686913v1?rss=1 Chundru, V. K. Wright, H. I. W. Frayling, T. M. Wood, A. R. Weedon, M. N. Wright, C. F. Beaumont, R. N. Hawkes, G. 2025-11-07 doi:10.1101/2025.11.06.686913 Cold Spring Harbor Laboratory Press 2025-11-07 <![CDATA[ Electron Cryo-Tomography Reveals the Caulobacter vibrioidesTight Adherence Pilus Architecture ]]> https://biorxiv.org/content/10.1101/2025.11.06.686991v1?rss=1 Maggi, S. Rosenzweig, R. Panis, G. Viollier, P. H. Jensen, G. J. 2025-11-07 doi:10.1101/2025.11.06.686991 Cold Spring Harbor Laboratory Press 2025-11-07 <![CDATA[ Researchers' perspectives on preregistration in animal research ]]> https://biorxiv.org/content/10.1101/2025.11.07.687141v1?rss=1 Priboi, C. Würbel, H. Mayer, B. Vergauwe, E. Elger, B. S. 2025-11-08 doi:10.1101/2025.11.07.687141 Cold Spring Harbor Laboratory Press 2025-11-08 <![CDATA[ Activation of oligonucleotide polyanions using collisions, electrons and photons in a timsOmni platform ]]> https://biorxiv.org/content/10.1101/2025.11.10.687689v1?rss=1 View larger version (36K): org.highwire.dtl.DTLVardef@534c32org.highwire.dtl.DTLVardef@af8ab0org.highwire.dtl.DTLVardef@ba2c3dorg.highwire.dtl.DTLVardef@ae9196_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Rosu, F. Chiba, R. Mani Mallika, A. Smyrnakis, A. Greisch, J.-F. Papanastasiou, D. Gabelica, V. 2025-11-10 doi:10.1101/2025.11.10.687689 Cold Spring Harbor Laboratory Press 2025-11-10 <![CDATA[ Targeting ligand binding sites in Plasmodium falciparum NCR1 enables antimalarial drug discovery ]]> https://biorxiv.org/content/10.1101/2025.11.11.687791v1?rss=1 Kohling, A. Boulet, C. Al Makhlouf, M. Khanppnavar, B. Chen, Y. Ganga, E. Kirchmair, J. Stockner, T. Brochet, M. Korkhov, V. M. 2025-11-11 doi:10.1101/2025.11.11.687791 Cold Spring Harbor Laboratory Press 2025-11-11 <![CDATA[ Minute- and second-scale hippocampal network dysfunctions in the 3xTgAD mouse model of Alzheimer's disease are prevented by TSPO knockout ]]> https://biorxiv.org/content/10.1101/2025.11.11.687784v1?rss=1 Vidal, B. Badina, A. M. Dorogan, V. Schirmbeck, G. Sanches, E. F. Ceyzeriat, K. Knoop, M. Abjean, L. Tsartsalis, S. Sizonenko, S. Baud, O. Millet, P. Zerbi, V. Tournier, B. B. 2025-11-12 doi:10.1101/2025.11.11.687784 Cold Spring Harbor Laboratory Press 2025-11-12 <![CDATA[ A self-organizing single-cell morphology circuit optimizes Podophrya collini predatory trap structure ]]> https://biorxiv.org/content/10.1101/2025.11.12.688106v1?rss=1 Xu, Z. Mazurkiewicz, L. E. Olivetta, M. Morrissey, M. Dudin, O. Weeks, A. M. Coyle, S. M. 2025-11-12 doi:10.1101/2025.11.12.688106 Cold Spring Harbor Laboratory Press 2025-11-12 <![CDATA[ Mycobacterial surface shedding drives bystander cells response during early intracellular infection ]]> https://biorxiv.org/content/10.1101/2025.11.13.687818v1?rss=1 D'Amico, D. Raykov, L. Soldati, T. Foulon, M. 2025-11-13 doi:10.1101/2025.11.13.687818 Cold Spring Harbor Laboratory Press 2025-11-13 <![CDATA[ A two-component system signaling hub controls enterococcal membrane remodeling in response to daptomycin ]]> https://biorxiv.org/content/10.1101/2025.11.16.688641v1?rss=1 Colomer-Winter, C. Nair, Z. J. Chua, J. Jabli, S. Roch, M. Cazenave-Gassiot, A. Sierra, R. Andrey, D. O. Chng, S.-S. Kline, K. A. 2025-11-17 doi:10.1101/2025.11.16.688641 Cold Spring Harbor Laboratory Press 2025-11-17 <![CDATA[ Transcriptional feedback of Erk signaling waves in zebrafish scale regeneration ]]> https://biorxiv.org/content/10.1101/2025.11.19.689292v1?rss=1 Coudeville, C. Guyomar, T. Allamand, J. Voigt, F. De Simone, A. 2025-11-19 doi:10.1101/2025.11.19.689292 Cold Spring Harbor Laboratory Press 2025-11-19 <![CDATA[ Impact of the pulse artifact on evoked activity in human wakefulness and sleep ]]> https://biorxiv.org/content/10.1101/2025.11.20.689416v1?rss=1 0.05, two-tailed) on the HEPs in N3 sleep and on the AEPs in all vigilance states. Our results emphasize the need to account for the PA as a significant confounding factor when comparing HEPs across groups with varying vascular or cardiac conditions. ]]> Cataldi, J. Pelentritou, A. Schwartz, S. De Lucia, M. 2025-11-20 doi:10.1101/2025.11.20.689416 Cold Spring Harbor Laboratory Press 2025-11-20 <![CDATA[ Enterococcus faecium colonization and persistence in a model of diabetic wound infection ]]> https://biorxiv.org/content/10.1101/2025.11.20.689639v1?rss=1 Jeyabalan, N. Tanoto, F. R. Antypas, H. Yi, C. N. J. Wen, R. T. J. Pethe, K. Becker, D. L. Stocks, C. J. Kline, K. A. 2025-11-21 doi:10.1101/2025.11.20.689639 Cold Spring Harbor Laboratory Press 2025-11-21 <![CDATA[ From Syllables to Words: EEG Evidence of Different Age Trajectories in Speech Tracking and Statistical Learning in Infants at High and Low Likelihood for Autism ]]> https://biorxiv.org/content/10.1101/2025.11.20.689632v1?rss=1 Godel, M. Flo, A. Benjamin, L. Dehaene-Lambertz, G. Schaer, M. 2025-11-23 doi:10.1101/2025.11.20.689632 Cold Spring Harbor Laboratory Press 2025-11-23 <![CDATA[ A divergent Plasmodium NEK4 acts as a key regulator driving the early events of meiosis ]]> https://biorxiv.org/content/10.1101/2025.11.21.689802v1?rss=1 Yanase, R. Hair, M. Zeeshan, M. Ferguson, D. J. P. Brady, D. Pasquarello, C. Bottrill, A. Bhanvadia, S. Neal, A. Tromer, E. C. Le Roch, K. G. Hainard, A. Holder, A. A. Vaughan, S. Guttery, D. S. Tewari, R. 2025-11-23 doi:10.1101/2025.11.21.689802 Cold Spring Harbor Laboratory Press 2025-11-23 <![CDATA[ A geothermal amoeba sets a new upper temperature limit for eukaryotes ]]> https://biorxiv.org/content/10.1101/2025.11.24.690213v1?rss=1 Rappaport, H. B. Petek-Seoane, N. A. Tyml, T. Mikus, F. Labutti, K. Ani, G. Niblo, J. K. MacVicar, E. Shepherd, R. M. de la Higuera, I. Lord, S. J. Dey, G. Wolfe, G. V. Dudin, O. Sukenik, S. Katz, L. A. Stedman, K. M. Skruber, K. Schulz, F. Mullins, R. D. Oliverio, A. M. 2025-11-24 doi:10.1101/2025.11.24.690213 Cold Spring Harbor Laboratory Press 2025-11-24 <![CDATA[ Mapping high resolution, multidimensional phase diagrams of physiological protein condensates ]]> https://biorxiv.org/content/10.1101/2025.11.24.690258v1?rss=1 Agarwal, T. Sneideris, T. Svara, F. Jermakovs, K. Coyle, H. Qamar, S. Kava, E. Scrutton, R. Pleschka, N. Peres, P. Cereghetti, G. Andrzejewska, E. Diaz-Barreiro, A. Palmer, G. Costa-Filho, A. J. Krainer, G. Knowles, T. P. Nixon-Abell, J. 2025-11-25 doi:10.1101/2025.11.24.690258 Cold Spring Harbor Laboratory Press 2025-11-25 <![CDATA[ Enterococcus faecalis alters antibiotic susceptibility in Pseudomonas aeruginosa mixed species biofilms. ]]> https://biorxiv.org/content/10.1101/2025.11.24.690246v1?rss=1 Anderson, C. Mattenberger, Y. Parga Martinez, A. Portalier, H. Tan, C. Esteban Henao, M. Viollier, P. H. Kline, K. A. 2025-11-26 doi:10.1101/2025.11.24.690246 Cold Spring Harbor Laboratory Press 2025-11-26 <![CDATA[ Redefining the role of the Plasmodium heme detoxification protein: From hemozoin formation to mitochondrial protein synthesis ]]> https://biorxiv.org/content/10.1101/2025.11.27.690934v1?rss=1 Sarrazin, L. Kloehn, J. Ziesmann, T. Schmitz, Y. Sandtmann, A.-L. Domenech-Eres, R. Scholz-Hoehn, K. Boulet, C. Distler, U. Matz, J. M. 2025-11-27 doi:10.1101/2025.11.27.690934 Cold Spring Harbor Laboratory Press 2025-11-27 <![CDATA[ An inositol pyrophosphate interaction screen provides insight into the regulation of plant casein kinase II ]]> https://biorxiv.org/content/10.1101/2025.11.27.691040v1?rss=1 Sturm, K. Pri-Tal, O. Rico-Resendiz, F. Verma, Y. Richter, A. Chen, H. Broger, L. Hothorn, L. A. Fiedler, D. Panse, V. G. Hothorn, M. 2025-11-29 doi:10.1101/2025.11.27.691040 Cold Spring Harbor Laboratory Press 2025-11-29 <![CDATA[ Molecular basis for cellular compartmentalization by an ancient membrane fission mechanism ]]> https://biorxiv.org/content/10.1101/2025.11.28.690958v1?rss=1 Espadas, J. Souza, D. P. Hakala, M. Garcia-Arcos, J. M. Tran, J. Kumar, A. Marcuello, C. Merino, A. Colom, A. Vanni, S. Kaksonen, M. Baum, B. Toret, C. P. Roux, A. 2025-11-29 doi:10.1101/2025.11.28.690958 Cold Spring Harbor Laboratory Press 2025-11-29 <![CDATA[ Aggressive Neuroblastomas Start Growing after Infancy ]]> https://biorxiv.org/content/10.64898/2025.11.28.691194v1?rss=1 Monyak, D. L. Holloway, S. T. Gumbert, G. J. Kim, K. Fong, A. Grimm, L. J. Marks, J. R. Ryser, M. D. Shibata, D. 2025-12-02 doi:10.64898/2025.11.28.691194 Cold Spring Harbor Laboratory Press 2025-12-02 <![CDATA[ Antibody peptide epitope conjugates for αPD-1 therapy-resistant head and neck squamous cell carcinoma ]]> https://biorxiv.org/content/10.64898/2025.11.28.691238v1?rss=1 Shui, Y. I. Millar, D. G. Altenburger, L. M. Chrisikos, T. Kalbfleisch, M. J. Hata, A. Sadow, P. M. Faquin, W. C. Martinot, A. J. Snyder, C. M. Pittet, M. J. Pai, S. I. Cobbold, M. Mempel, T. R. 2025-12-02 doi:10.64898/2025.11.28.691238 Cold Spring Harbor Laboratory Press 2025-12-02 <![CDATA[ Multiple task-demands flexibly optimize neural geometry in human ventral temporal cortex ]]> https://biorxiv.org/content/10.64898/2025.11.30.691163v1?rss=1 Nigam, T. Campos-Perez, A. F. Megevand, P. Vidal, J. Perrone-Bertolotti, M. Kahane, P. Thesen, T. Devinsky, O. Melloni, L. Schwiedrzik, C. M. 2025-12-02 doi:10.64898/2025.11.30.691163 Cold Spring Harbor Laboratory Press 2025-12-02 <![CDATA[ Variation in cultural attitude, knowledge and individual motivational factors impact engagement and tool use in a field experiment in wild chimpanzees ]]> https://biorxiv.org/content/10.64898/2025.12.01.691567v1?rss=1 Mannion, K. R. Ndora, M. Kugonza, S. Gruber, T. 2025-12-02 doi:10.64898/2025.12.01.691567 Cold Spring Harbor Laboratory Press 2025-12-02 <![CDATA[ Redundancy masks functional specificity of SMARCD paralogs in neurodevelopment ]]> https://biorxiv.org/content/10.64898/2025.12.05.692564v1?rss=1 So, Y. Soldati, H. Anselme, L. Braun, S. M. G. 2025-12-07 doi:10.64898/2025.12.05.692564 Cold Spring Harbor Laboratory Press 2025-12-07 <![CDATA[ Refined shoulder kinematics via markerless bony landmark detection and acromial 3D shape using an RGB-D camera during hand-cycling ]]> https://biorxiv.org/content/10.64898/2025.12.04.692368v1?rss=1 Ceglia, A. Mulhaupt, L. Moissenet, F. Begon, M. Seoud, L. 2025-12-09 doi:10.64898/2025.12.04.692368 Cold Spring Harbor Laboratory Press 2025-12-09 <![CDATA[ A Transferable and Robust Computational Framework for Class A GPCR Activation Free Energies ]]> https://biorxiv.org/content/10.64898/2025.12.05.692536v1?rss=1 View larger version (6K): org.highwire.dtl.DTLVardef@9fae49org.highwire.dtl.DTLVardef@16b5288org.highwire.dtl.DTLVardef@f79af1org.highwire.dtl.DTLVardef@1dd71d8_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Aureli, S. Piasentin, N. Frohlking, T. Rizzi, V. Gervasio, F. L. 2025-12-09 doi:10.64898/2025.12.05.692536 Cold Spring Harbor Laboratory Press 2025-12-09 <![CDATA[ Attentional focus and emotion modulate voice recognition deficits in cerebellar stroke patients ]]> https://biorxiv.org/content/10.64898/2025.12.08.692937v1?rss=1 Ceravolo, L. Stiennon, E. Constantin, I. Chassot, E. Thomasson, M. Pierce, J. Sveikata, L. Cionca, A. Ronchi, R. Carrera, E. Grandjean, D. Assal, F. Peron, J. 2025-12-10 doi:10.64898/2025.12.08.692937 Cold Spring Harbor Laboratory Press 2025-12-10 <![CDATA[ CleLight: A scalable 3D histology pipeline for mappingneurodegenerative and psychiatric pathology in archivalhuman brains ]]> https://biorxiv.org/content/10.64898/2025.12.10.693496v1?rss=1 Jorda-Siquier, T. Scholler, J. Gantar, I. Policet-Betend, H. Batti, L. Pages, S. Kovari, E. Lamy, C. M. 2025-12-13 doi:10.64898/2025.12.10.693496 Cold Spring Harbor Laboratory Press 2025-12-13 <![CDATA[ Human POLD3 coordinates leading and lagging strand in Mitotic DNA Synthesis ]]> https://biorxiv.org/content/10.64898/2025.12.15.694317v1?rss=1 Turati, D. Dionellis, V. S. Tropia, L. Halazonetis, T. D. 2025-12-16 doi:10.64898/2025.12.15.694317 Cold Spring Harbor Laboratory Press 2025-12-16 <![CDATA[ Control of cellular cortical tension and shape by RhoGTPase signalling ]]> https://biorxiv.org/content/10.64898/2025.12.15.694413v1?rss=1 Bohec, P. Khoromskaia, D. Kelkar, M. Ferber, E. Duprez, G. Lavoie, G. Valon, L. Roux, P. P. Salbreux, G. Charras, G. 2025-12-17 doi:10.64898/2025.12.15.694413 Cold Spring Harbor Laboratory Press 2025-12-17 <![CDATA[ Functional architecture of cardiac TF regulatory landscapes in control of mammalian heart development ]]> https://biorxiv.org/content/10.64898/2025.12.19.695499v1?rss=1 Roland, V. Tuechler, J. Esposito, A. Conte, M. Zoia, M. Wisnumurti, E. Tissieres, V. Gamart, J. Rouco Garcia, R. Marques, I. J. Akshay, A. Rapp, V. Mannion, B. J. Akiyama, J. A. Arora, P. Walker, H. Hashemi Gheinani, A. Firulli, B. A. Nusspaumer, G. Firulli, A. B. Andrey, G. Visel, A. Mercader, N. Lopez-Rios, J. Nicodemi, M. Barozzi, I. Osterwalder, M. 2025-12-22 doi:10.64898/2025.12.19.695499 Cold Spring Harbor Laboratory Press 2025-12-22 <![CDATA[ Nose-to-ground distance drives the evolution of mammalian odorant receptor repertoire size ]]> https://biorxiv.org/content/10.64898/2025.12.23.695377v1?rss=1 Tuberosa, J. Furlan, F.-M. Carleton, A. Rodriguez, I. 2025-12-24 doi:10.64898/2025.12.23.695377 Cold Spring Harbor Laboratory Press 2025-12-24 <![CDATA[ Introducing a translationally relevant mouse model of radiosurgery-induced unilateral hearing loss ]]> https://biorxiv.org/content/10.64898/2025.12.23.696156v1?rss=1 Daskalou, D. Rousset, F. Sgroi, S. Oberhauser, L. Thiran, J.-P. Tuleasca, C. Jelescu, I. Levivier, M. Senn, P. 2025-12-25 doi:10.64898/2025.12.23.696156 Cold Spring Harbor Laboratory Press 2025-12-25 <![CDATA[ Dopamine drives a positive reward bias on human reinforcement learning ]]> https://biorxiv.org/content/10.64898/2025.12.24.696333v1?rss=1 zalta, a. Skvortsova, V. Hewitt, S. R. Moutoussis, M. Nour, M. M. Dolan, R. J. Findling, C. Hauser, T. U. Wyart, V. 2025-12-26 doi:10.64898/2025.12.24.696333 Cold Spring Harbor Laboratory Press 2025-12-26 <![CDATA[ Single-cell RNA sequencing identifies progenitor dysfunction, inflammation and premature aging in ex vivo airway epithelium-derived from transplant recipients ]]> https://biorxiv.org/content/10.64898/2025.12.26.696372v1?rss=1 bondeelle, l. bezrukov, f. berra, g. chalandon, y. gensous, c. loison, s. giannotti, f. messe, r. Le Goff, J. clement, s. Tapparel, C. bergeron, a. 2025-12-26 doi:10.64898/2025.12.26.696372 Cold Spring Harbor Laboratory Press 2025-12-26 <![CDATA[ Myeloid reprogramming by poly(I:C) recruits progenitor-exhausted CD8+ T cells and sensitizes rhabdoid tumors to PD-1 blockade ]]> https://biorxiv.org/content/10.64898/2025.12.29.696858v1?rss=1 Manriquez, V. Cavada-Silva, S. Beccaria, K. Niborski, L. L. Leruste, A. Richer, W. Vandenbogaert, M. Han, Z.-Y. Sedlik, C. Denizeau, J. Mesple, J. Fusilier, Z. Lesage L., L. Goldstein, J. Gerber-Ferder, Y. Fitte-Duval, S. Marziali, F. Mena-Osuna, R. Tosello-Boari, J. Bouarich-Bourimi, R. Pacini, M.-F. Missolo-koussou, Y. Bohec, M. Baulande, S. Benaroch, P. Helft, J. Moreau, H. D. Waterfall, J. J. Bourdeaut, F. Piaggio, E. 2025-12-29 doi:10.64898/2025.12.29.696858 Cold Spring Harbor Laboratory Press 2025-12-29 <![CDATA[ Puf3 contributes to changes in mRNA solubility, translation elongation dynamics at rare arginine codons and loss of protein homeostasis in cells lacking Not4 ]]> https://biorxiv.org/content/10.64898/2025.12.31.695943v1?rss=1 View larger version (18K): org.highwire.dtl.DTLVardef@855afdorg.highwire.dtl.DTLVardef@118addaorg.highwire.dtl.DTLVardef@13dd015org.highwire.dtl.DTLVardef@12824c6_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Collart, M. Audebert, L. Allen, G. E. Chen, S. Panasenko, O. O. Huch, S. Polte, C. Ignatova, Z. O. Pelechano, V. 2026-01-01 doi:10.64898/2025.12.31.695943 Cold Spring Harbor Laboratory Press 2026-01-01 <![CDATA[ A Glycosylation-Dependent Checkpoint Restrains Intestinal Intra-Epithelial Lymphocyte Activation ]]> https://biorxiv.org/content/10.64898/2026.01.02.697332v1?rss=1 Cheng, L. Bianchi, N. Soldati, H. Bersier, L. Evrard, M. Caillon, A. Chawla, A. S. Nakken, B. Szodoray, P. Bousser, E. D. Festjens, N. Petrova, T. V. Lemeille, S. Mackay, L. K. Callewaert, N. Swamy, M. Braun, S. M. G. Becattini, S. 2026-01-02 doi:10.64898/2026.01.02.697332 Cold Spring Harbor Laboratory Press 2026-01-02 <![CDATA[ MyoL-Dependent Coupling of Preconoidal Rings to Conoid Is Required for Motility in Toxoplasma gondii ]]> https://biorxiv.org/content/10.64898/2026.01.06.697858v1?rss=1 Haase, R. Tell i Puig, A. Dos Santos Pacheco, N. Maco, B. Vadas, O. Soldati-Favre, D. 2026-01-06 doi:10.64898/2026.01.06.697858 Cold Spring Harbor Laboratory Press 2026-01-06 <![CDATA[ SLBP-independent control of maternal histone mRNA ]]> https://biorxiv.org/content/10.64898/2026.01.06.697898v1?rss=1 Ketting, R. F. Falk, S. Koenig, J. Steiner, F. Delaney, K. Seistrup, A.-S. Podvalnaya, N. Busch, A. Govind, S. Brehm, M. Pereirinha, J. 2026-01-06 doi:10.64898/2026.01.06.697898 Cold Spring Harbor Laboratory Press 2026-01-06 <![CDATA[ Tracing the Neanderthal-Modern Human hybrid zone using paleogenomic data ]]> https://biorxiv.org/content/10.64898/2026.01.06.697899v1?rss=1 Di Santo, L. N. Quilodran, C. S. Cerrito, P. Currat, M. 2026-01-06 doi:10.64898/2026.01.06.697899 Cold Spring Harbor Laboratory Press 2026-01-06 <![CDATA[ Dynamic S-acylation controls CMG2 maturation, extracellular matrix regulation, and anthrax toxin entry ]]> https://biorxiv.org/content/10.64898/2026.01.06.697925v1?rss=1 Abrami, L. Blaskovic, S. Joliot, O. Mercier, V. Kunz, B. mesquita, F. S. van der Goot, F. G. 2026-01-07 doi:10.64898/2026.01.06.697925 Cold Spring Harbor Laboratory Press 2026-01-07 <![CDATA[ A teichoic acid-like wall modification associated with immune suppression is socially regulated in Streptococcus pyogenes ]]> https://biorxiv.org/content/10.64898/2026.01.07.698140v1?rss=1 Anderson, C. Wilkening, R. V. Boulos, S. Keys, T. Ebert, M.-O. Zinsli, L. V. Krusche, J. Loessner, M. J. Feldstein, S. F. Chang, J. C. Peschel, A. Horswill, A. R. Shen, Y. Federle, M. J. 2026-01-08 doi:10.64898/2026.01.07.698140 Cold Spring Harbor Laboratory Press 2026-01-08 <![CDATA[ Emotional modulation of visual cortical reactivation during true and false memories ]]> https://biorxiv.org/content/10.64898/2026.01.08.694977v1?rss=1 Hofstetter, C. Riegel, M. Igloi, K. Pichon, A. Vuilleumier, P. 2026-01-09 doi:10.64898/2026.01.08.694977 Cold Spring Harbor Laboratory Press 2026-01-09 <![CDATA[ Love-thy-neighbor: Neural networks for tracking and lineage tracing in budding yeast ]]> https://biorxiv.org/content/10.64898/2026.01.09.698579v1?rss=1 Zelic, M. Gligorovski, V. Labbaf, F. Labagnara, M. Oesterle, R. Brenna, G. Massard, F. Chethan, S. G. Li, W. Martin, S. G. Hauf, S. Rahi, S. J. 2026-01-09 doi:10.64898/2026.01.09.698579 Cold Spring Harbor Laboratory Press 2026-01-09 <![CDATA[ Early metabolic reprogramming licenses Streptococcus pneumoniae for Influenza-driven superinfection ]]> https://biorxiv.org/content/10.64898/2026.01.10.698720v1?rss=1 Lagune, M. Bianchi, N. Herren, M. Prados, J. Caillon, A. Kulkarni, G. Silva, F. Von Rohr, O. Sierra, R. Colpaert, M. Gentry, M. Veening, J.-w. Kloehn, J. Schmolke, M. Becattini, S. 2026-01-10 doi:10.64898/2026.01.10.698720 Cold Spring Harbor Laboratory Press 2026-01-10 <![CDATA[ Multiscale curvature modulates epithelial architecture and nuclear organization. ]]> https://biorxiv.org/content/10.64898/2026.01.12.698973v1?rss=1 Luciano, M. Vagne, Q. Pernollet, G. Salbreux, G. Tomba, C. Roux, A. 2026-01-12 doi:10.64898/2026.01.12.698973 Cold Spring Harbor Laboratory Press 2026-01-12 <![CDATA[ An engineered nanobody inhibitor for molecular-to-circuit control of opioid receptor function ]]> https://biorxiv.org/content/10.64898/2026.01.12.698943v1?rss=1 Valbret, Z. Lamothe-Molina, P. L. Papadogkonaki, S. Koehl, A. Arafiles, J. V. V. Shapiro Tuchman, Z. Fisher, N. M. Radoux-Mergault, A. Canziani, A. Huang, G. Von Zastrow, M. Kosloff, M. Hackenberger, C. P. Manglik, A. Patriarchi, T. Stoeber, M. 2026-01-14 doi:10.64898/2026.01.12.698943 Cold Spring Harbor Laboratory Press 2026-01-14 <![CDATA[ Analysis of 3D epithelial tissue packing reveals correlated patterns of cell height and skewing ]]> https://biorxiv.org/content/10.64898/2026.01.14.699560v1?rss=1 Pernollet, G. E. Vagne, Q. Garcia-Arcos, J. M. Dessalles, C. A. Salbreux, G. Roux, A. 2026-01-15 doi:10.64898/2026.01.14.699560 Cold Spring Harbor Laboratory Press 2026-01-15 <![CDATA[ Feeling the music: Audiotactile encoding of temporal structure in the human brain ]]> https://biorxiv.org/content/10.64898/2026.01.17.700057v1?rss=1 Degano, G. Ferrari, A. Noppeney, U. 2026-01-18 doi:10.64898/2026.01.17.700057 Cold Spring Harbor Laboratory Press 2026-01-18 <![CDATA[ Molecular basis of mitogen-activated protein kinase ERK2 activation by its upstream kinase MEK1 ]]> https://biorxiv.org/content/10.64898/2026.01.19.700303v1?rss=1 von Velsen, J. Juyoux, P. Piasentin, N. Fisher, H. Lapouge, K. Vadas, O. Gervasio, F. L. Bowler, M. W. 2026-01-19 doi:10.64898/2026.01.19.700303 Cold Spring Harbor Laboratory Press 2026-01-19 <![CDATA[ Optogenetically Evoked Accumbal Dopamine Transients Are Sufficient to Drive Locomotor Sensitization and Cross-Sensitization to Cocaine ]]> https://biorxiv.org/content/10.64898/2026.01.16.699633v1?rss=1 Wang, X. E. Hiver, A. Luscher, C. Pascoli, V. 2026-01-20 doi:10.64898/2026.01.16.699633 Cold Spring Harbor Laboratory Press 2026-01-20 <![CDATA[ The Joubert gene TMEM67 is required for the correct establishment of spinal dorsal identities in human organoids. ]]> https://biorxiv.org/content/10.64898/2026.01.20.700675v1?rss=1 Wiegering, A. Bools, K. Anselme, I. Metayer-Derout, L. Mercey, O. Balissat, E. Bijek, Y. Catala, M. Schneider-Maunoury, S. Stedman, A. 2026-01-20 doi:10.64898/2026.01.20.700675 Cold Spring Harbor Laboratory Press 2026-01-20 <![CDATA[ Microstate Dynamics of Focused Attention Meditation ]]> https://biorxiv.org/content/10.64898/2026.01.19.700274v1?rss=1 Ngo, C. Bek, E. Stasytyte, M. Newman, L. Elizalde, R. Kanthi, A. Manjunath, N. Michel, C. M. 2026-01-22 doi:10.64898/2026.01.19.700274 Cold Spring Harbor Laboratory Press 2026-01-22 <![CDATA[ Microbiopsy of living mouse brain for longitudinal molecular profiling ]]> https://biorxiv.org/content/10.64898/2026.01.22.701044v1?rss=1 Hoyningen, A. Ramisch, A. Fellouse, L. Hiver, A. Lingenberg, A. Luscher, C. Marion-Poll, L. 2026-01-24 doi:10.64898/2026.01.22.701044 Cold Spring Harbor Laboratory Press 2026-01-24 <![CDATA[ Live dynamics of induced cell-cell fusion between mitotic and interphasic cells ]]> https://biorxiv.org/content/10.64898/2026.01.27.700572v1?rss=1 Afonso, O. Feliciano, D. Lippincott-Schwartz, J. 2026-01-27 doi:10.64898/2026.01.27.700572 Cold Spring Harbor Laboratory Press 2026-01-27 <![CDATA[ Low-salt diet induces claudin-3 expression and drives adaptive changes in collecting duct of claudin-3-deficient mice ]]> https://biorxiv.org/content/10.64898/2026.01.26.701749v1?rss=1 SASSI, A. Chassot, A. Jellali, S. Liaudet, N. Polat, A. Baier, F. Stroka, D. Furuse, M. Feraille, E. 2026-01-28 doi:10.64898/2026.01.26.701749 Cold Spring Harbor Laboratory Press 2026-01-28 <![CDATA[ PAK-family kinases promote cell fusion irreversibility by preventing cell wall repair ]]> https://biorxiv.org/content/10.64898/2026.01.27.701985v1?rss=1 Coronas-Serna, J. M. Perez-Berna, A. J. Martin, S. G. 2026-01-28 doi:10.64898/2026.01.27.701985 Cold Spring Harbor Laboratory Press 2026-01-28 <![CDATA[ PefA, an ALG-2-like Ca2+ sensor, regulates ESCRT and autophagy responses to mycobacterial vacuole damage ]]> https://biorxiv.org/content/10.64898/2026.01.30.702722v1?rss=1 Guallar-Garrido, S. Perret, A. Carreras-Sureda, A. Michard, C. Soldati, T. 2026-01-30 doi:10.64898/2026.01.30.702722 Cold Spring Harbor Laboratory Press 2026-01-30 <![CDATA[ A redox-regulated RCC1-like protein controls catalase activity in Arabidopsis ]]> https://biorxiv.org/content/10.64898/2026.01.30.702735v1?rss=1 Hu, Z. Stolze, S. C. Mhamdi, A. Van Breusegem, F. Nakagami, H. Ulm, R. 2026-01-30 doi:10.64898/2026.01.30.702735 Cold Spring Harbor Laboratory Press 2026-01-30 <![CDATA[ A Conserved Locus Coeruleus fMRI Signature of Brain-State Transitions across Sleep, Anesthesia, and Wakefulness ]]> https://biorxiv.org/content/10.64898/2026.01.28.702261v1?rss=1 Barcellini, F. Foustoukos, G. Wenz, D. Munn, B. R. Shine, J. M. Fernandez, L. M. J. Luthi, A. Zerbi, V. 2026-01-31 doi:10.64898/2026.01.28.702261 Cold Spring Harbor Laboratory Press 2026-01-31 <![CDATA[ Tipping the balance: Synthesis and evaluation of centrinone-based degraders of polo-like kinase 4 ]]> https://biorxiv.org/content/10.64898/2026.01.31.703010v1?rss=1 Kovacevic, A. Salim, A. Borges, C. Meraldi, P. Hoogendoorn, S. 2026-02-03 doi:10.64898/2026.01.31.703010 Cold Spring Harbor Laboratory Press 2026-02-03 <![CDATA[ Federated cross-biobank conditional analysis identifies LDL-C lowering effects of DNAJC13 haploinsufficiency and LDLR regulation ]]> https://biorxiv.org/content/10.64898/2026.02.03.702791v1?rss=1 Wright, H. I. W. Darrous, L. Ferrat, L. Chundru, V. K. Kamoun, A. Wood, A. R. Wright, C. F. Patel, K. A. Frayling, T. M. Weedon, M. N. Beaumont, R. N. Hawkes, G. 2026-02-05 doi:10.64898/2026.02.03.702791 Cold Spring Harbor Laboratory Press 2026-02-05 <![CDATA[ Layer-specific functional gradients uncover intrinsic-network organization and feedback processing ]]> https://biorxiv.org/content/10.64898/2026.02.06.704362v1?rss=1 Degutis, J. K. Miehlbradt, J. Durand-Ruel, M. Huppi, P. Van De Ville, D. 2026-02-07 doi:10.64898/2026.02.06.704362 Cold Spring Harbor Laboratory Press 2026-02-07 <![CDATA[ Coordinated control of both microtubule ends regulates mitotic spindle length ]]> https://biorxiv.org/content/10.64898/2026.02.08.704347v1?rss=1 Fiorenza, S. A. Cheeran, S. Doria, E. Tolic, I. M. Meraldi, P. Pavin, N. 2026-02-09 doi:10.64898/2026.02.08.704347 Cold Spring Harbor Laboratory Press 2026-02-09 <![CDATA[ Individual differences of cortical and subcortical emotion-informed functional gradients ]]> https://biorxiv.org/content/10.64898/2026.02.09.704784v1?rss=1 Chan, C. H. M. Vilaclara, L. Vuilleumier, P. Van De Ville, D. Morgenroth, E. 2026-02-09 doi:10.64898/2026.02.09.704784 Cold Spring Harbor Laboratory Press 2026-02-09 <![CDATA[ Metabolomic and Transcriptomic rewiring between virus resistance and susceptibility in Ostreococcus mediterraneus ]]> https://biorxiv.org/content/10.64898/2026.02.10.705097v1?rss=1 James, A. Marcellin-Gros, R. Yau, S. Stien, D. Piganeau, G. 2026-02-10 doi:10.64898/2026.02.10.705097 Cold Spring Harbor Laboratory Press 2026-02-10 <![CDATA[ Intracellular compartmentalization shapes lipid access and metabolic fitness of mycobacteria ]]> https://biorxiv.org/content/10.64898/2026.02.10.704997v1?rss=1 Foulon, M. Huettel, S. V. Breitsprecher, L. Gauda, W. Raykov, L. Koliwer-Brandl, H. Ohlhagen, M. Thuenauer, R. Schwudke, D. Hilbi, H. Soldati, T. Barisch, C. 2026-02-11 doi:10.64898/2026.02.10.704997 Cold Spring Harbor Laboratory Press 2026-02-11 <![CDATA[ Energetic cross-talk of filter gate and lower helices drives polymodal regulation and disease in TREK K2P channels ]]> https://biorxiv.org/content/10.64898/2026.02.13.705734v1?rss=1 Sun, H. Tuerkaydin, B. Rizzi, V. Benkerdagh, C. Ghysbrecht, S. Aureli, S. Baukrowitz, T. Schewe, M. Gervasio, F. L. 2026-02-14 doi:10.64898/2026.02.13.705734 Cold Spring Harbor Laboratory Press 2026-02-14 <![CDATA[ Germline Blastomeres transcriptomics in the presence or absence of PIE-1 during C. elegans early embryogenesis ]]> https://biorxiv.org/content/10.64898/2026.02.14.705883v1?rss=1 Ponsard, P. Stubbe, F.-X. Tricquet, P. Mello, C. Hermand, D. 2026-02-14 doi:10.64898/2026.02.14.705883 Cold Spring Harbor Laboratory Press 2026-02-14 <![CDATA[ Viral rewiring of APC/C-CDC20 drives Aurora B hyperubiquitination, mitotic regression and polyploidy ]]> https://biorxiv.org/content/10.64898/2026.02.13.705602v1?rss=1 Srivastava, S. Sengupta, D. Jasiqi, Y. Povolo, V. R. Bauer, M. Hubert, M. Haselmann, U. Schneider, M. Helm, D. Greber, U. F. Prasad, V. 2026-02-15 doi:10.64898/2026.02.13.705602 Cold Spring Harbor Laboratory Press 2026-02-15 <![CDATA[ Fast-ripples are emergent properties of neuronal networks ]]> https://biorxiv.org/content/10.64898/2026.02.15.706005v1?rss=1 Sheybani, L. Qiu, Y. Singh, P. K. Vivekananda, U. Burgess, N. Diehl, B. McEvoy, A. W. Miserocchi, A. Bisby, J. A. Shekh-Ahmad, T. Lignani, G. Bush, D. Walker, M. 2026-02-17 doi:10.64898/2026.02.15.706005 Cold Spring Harbor Laboratory Press 2026-02-17 <![CDATA[ Human Cerebral Cortex Organization Characterized by Functional PET-FDG "Metabolic Connectivity" ]]> https://biorxiv.org/content/10.64898/2026.02.15.706044v1?rss=1 Du, P. Coursey, S. E. Xu, T. Jamadar, S. D. Nolin, S. A. Wan, B. Wey, H.-Y. Polimeni, J. R. Price, J. C. Liu, Q. Chen, J. E. 2026-02-17 doi:10.64898/2026.02.15.706044 Cold Spring Harbor Laboratory Press 2026-02-17 <![CDATA[ Microtubules sustain the fidelity of cellularization in a coenocytic relative of animals ]]> https://biorxiv.org/content/10.64898/2026.02.16.706138v1?rss=1 Araujo, M. Olivetta, M. Ronchi, P. Oorschot, V. Khan, A. Tischer, C. Shah, H. Dey, G. Dudin, O. 2026-02-17 doi:10.64898/2026.02.16.706138 Cold Spring Harbor Laboratory Press 2026-02-17 <![CDATA[ Tracing Neanderthal ancestry patterns through successive population expansions in Europe ]]> https://biorxiv.org/content/10.64898/2026.02.20.706963v1?rss=1 Tsoupas, A. Quilodran, C. S. Rio, J. Currat, M. 2026-02-20 doi:10.64898/2026.02.20.706963 Cold Spring Harbor Laboratory Press 2026-02-20 <![CDATA[ Breast cancer metabolism and responsiveness to dichloroacetate: relationships with 15N and 13C natural abundance ]]> https://biorxiv.org/content/10.64898/2026.03.09.710495v1?rss=1 View larger version (32K): org.highwire.dtl.DTLVardef@1589d0eorg.highwire.dtl.DTLVardef@af2ad4org.highwire.dtl.DTLVardef@24e67forg.highwire.dtl.DTLVardef@98da7f_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> TEA, I. Letertre, M. Boccard, J. Schiphorst, A.-M. Blanchet, S. Croyal, M. Blackburn, A. C. Tcherkez, G. G. B. 2026-03-09 doi:10.64898/2026.03.09.710495 Cold Spring Harbor Laboratory Press 2026-03-09 <![CDATA[ Cultural norms of exogamy and mobility shape hunter-gatherer genetic evolution ]]> https://biorxiv.org/content/10.64898/2026.03.10.710787v1?rss=1 Padilla-Iglesias, C. Nganga, D. Amboulou, E. Ruf, J. Gerbault, P. Docquier, M. Vinicius, L. Manica, A. Migliano, A. 2026-03-11 doi:10.64898/2026.03.10.710787 Cold Spring Harbor Laboratory Press 2026-03-11 <![CDATA[ Joint Geometric--Chemical Distance for Protein Surfaces ]]> https://biorxiv.org/content/10.64898/2026.03.10.710722v1?rss=1 Swami, H. Eckmann, J.-P. McBride, J. M. Tlusty, T. 2026-03-12 doi:10.64898/2026.03.10.710722 Cold Spring Harbor Laboratory Press 2026-03-12 <![CDATA[ Wild chimpanzees in Bugoma Forest, Uganda follow the Ugandan feeding ecology etiquette but exhibit cultural singularities: a case for the cultural junction hypothesis ]]> https://biorxiv.org/content/10.64898/2026.03.10.710845v1?rss=1 Mannion, K. R. Hobaiter, C. Gruber, T. 2026-03-12 doi:10.64898/2026.03.10.710845 Cold Spring Harbor Laboratory Press 2026-03-12 <![CDATA[ Cortical excitability inversely modulates fMRI connectivity via low-frequency neuronal coupling ]]> https://biorxiv.org/content/10.64898/2026.03.12.710517v1?rss=1 Sastre-Yague, D. Blanco Malerba, S. Rocchi, F. Gini, S. Mancini, G. Stuefer, A. Coletta, L. Noei, S. Markicevic, M. Alvino, F. G. Zerbi, V. Galbusera, A. MAriani, J. C. Panzeri, S. Gozzi, A. 2026-03-14 doi:10.64898/2026.03.12.710517 Cold Spring Harbor Laboratory Press 2026-03-14 <![CDATA[ FLASH Radiotherapy is faster than a heartbeat: A compartmental model to illustrate the interplay between tissue oxygen perfusion and ultra-high dose rate effects. ]]> https://biorxiv.org/content/10.64898/2026.03.12.711443v1?rss=1 Ballesteros-Zebadua, P. Jansen, J. Grilij, V. Franco-Perez, J. Vozenin, M.-C. Abolfath, R. 2026-03-16 doi:10.64898/2026.03.12.711443 Cold Spring Harbor Laboratory Press 2026-03-16 <![CDATA[ Htr3a receptors control attenuation of fear responses by modulating the corticolimbic network activity and synchronization ]]> https://biorxiv.org/content/10.64898/2026.03.16.711072v1?rss=1 Zewdie, S. MARISSAL, T. Birot, G. Schaller, K. Dayer, A. Quairiaux, C. 2026-03-18 doi:10.64898/2026.03.16.711072 Cold Spring Harbor Laboratory Press 2026-03-18 <![CDATA[ A biochemical probe for microtubule lattice integrity uncovers motor-caused lattice damage ]]> https://biorxiv.org/content/10.64898/2026.03.16.711994v1?rss=1 Aumeier, C. Egoldt, C. Reymond, L. Tran, J. Salim, A. Velluz, M.-C. Hoogendoorn, S. 2026-03-18 doi:10.64898/2026.03.16.711994 Cold Spring Harbor Laboratory Press 2026-03-18 <![CDATA[ Sensory processing reallocation from external to internal signals in REM sleep ]]> https://biorxiv.org/content/10.64898/2026.03.16.712081v1?rss=1 View larger version (19K): org.highwire.dtl.DTLVardef@1e46a9borg.highwire.dtl.DTLVardef@112f050org.highwire.dtl.DTLVardef@5f5249org.highwire.dtl.DTLVardef@135cc4_HPS_FORMAT_FIGEXP M_FIG C_FIG ]]> Cataldi, J. Pelentritou, A. Schwartz, S. De Lucia, M. 2026-03-18 doi:10.64898/2026.03.16.712081 Cold Spring Harbor Laboratory Press 2026-03-18 <![CDATA[ Early microglial activation in the TME enables FLASH-RT to eradicate medulloblastoma while promoting neuron-astrocyte crosstalk to minimize toxicity in the hippocampus ]]> https://biorxiv.org/content/10.64898/2026.03.16.712103v1?rss=1 Knol, M. Franco Perez, J. Almeida, A. Kunz, L. v. Petit, B. Job, A. Ollivier, J. Romero, C. J. Jansen, J. Grilj, V. Limoli, C. Vozenin, M.-C. Ballesteros Zebadua, P. 2026-03-18 doi:10.64898/2026.03.16.712103 Cold Spring Harbor Laboratory Press 2026-03-18 <![CDATA[ Diffractive scanning live volumetric two-photon microscopy within the contracting mouse intestine ]]> https://biorxiv.org/content/10.64898/2026.03.18.712419v1?rss=1 Jurkevicius, J. Alata, M. Wiggert, M. Rixius, M. Reinhards, S. Thielking, M. Stock, C. Favre, A. Fung, C. Theissen-Kunde, D. Bonacina, L. Karpf, S. Vanden Berghe, P. 2026-03-20 doi:10.64898/2026.03.18.712419 Cold Spring Harbor Laboratory Press 2026-03-20 <![CDATA[ Structure of the Arabidopsis receptor kinase SRF6 ectodomain determined from crystals obtained using the LRR crystallisation screen ]]> https://biorxiv.org/content/10.64898/2026.03.20.713188v1?rss=1 Caregnato, A. Hohmann, U. 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