bioRxiv Subject Collection: Synthetic Biology
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This feed contains articles for bioRxiv Subject Collection "Synthetic Biology"
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Hierarchical tissue structure creates history-dependent barriers to clonal invasion
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https://www.biorxiv.org/content/10.64898/2026.08.04.742588v1?rss=1
2026-08-10doi:10.64898/2026.08.04.742588Cold Spring Harbor Laboratory2026-08-10
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Minimizing time in culture: A prototypic autologous manufacturing workflow for monoclonal iPSC lines within seven weeks
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https://www.biorxiv.org/content/10.64898/2026.08.04.741960v1?rss=1
2026-08-10doi:10.64898/2026.08.04.741960Cold Spring Harbor Laboratory2026-08-10
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The chromatin reader protein MLLT1 is critical to maintain normal B lymphopoiesis
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https://www.biorxiv.org/content/10.64898/2026.08.08.743534v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743534Cold Spring Harbor Laboratory2026-08-10
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Evolution of mechanical chromatin insulators from selfish genetic elements
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https://www.biorxiv.org/content/10.64898/2026.08.08.743475v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743475Cold Spring Harbor Laboratory2026-08-10
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Sample-specific protein-protein interaction networks inferred from transcriptomics and proteomics show high similarities
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https://www.biorxiv.org/content/10.64898/2026.08.09.743737v1?rss=1
2026-08-10doi:10.64898/2026.08.09.743737Cold Spring Harbor Laboratory2026-08-10
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Double Machine Learning with Multi-Gene Shared Backgroundfor Causal Inference in Single-Cell Data: Grouping Deviation Follows a Random Walk and the Accuracy-Compute Trade-Off
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https://www.biorxiv.org/content/10.64898/2026.08.08.743701v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743701Cold Spring Harbor Laboratory2026-08-10
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Engineering Binding Efficiency and Interaction Stability of a Thermostable Cohesin-Dockerin Pair on the Bacterial Cell Surface
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https://www.biorxiv.org/content/10.64898/2026.08.09.743725v1?rss=1
2026-08-10doi:10.64898/2026.08.09.743725Cold Spring Harbor Laboratory2026-08-10
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Systematic mapping of orthogonality and domain-swap permissiveness across LysR-type transcriptional biosensors
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https://www.biorxiv.org/content/10.64898/2026.08.07.743483v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743483Cold Spring Harbor Laboratory2026-08-10
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Augmenting Radiation Sensitivity by Targeting PAR-Dependent Replication Fork Vulnerability in IDH-Mutant Glioma
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https://www.biorxiv.org/content/10.64898/2026.08.08.743634v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743634Cold Spring Harbor Laboratory2026-08-10
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Extracellular vesicle-mediated suppression of macrophage STING signaling promotes immune dysfunction in dedifferentiated liposarcoma
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https://www.biorxiv.org/content/10.64898/2026.08.07.743624v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743624Cold Spring Harbor Laboratory2026-08-10
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Regulatory mutants of the Tbx1 gene alter transcription programs of lineage determination and patterning in early mesoderm.
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https://www.biorxiv.org/content/10.64898/2026.08.08.743664v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743664Cold Spring Harbor Laboratory2026-08-10
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Generation of Human Taste Bud Organoids as a Human-Mimetic Platform for Modeling Taste Perception
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https://www.biorxiv.org/content/10.64898/2026.08.09.743674v1?rss=1
, and identified previously unrecognized molecular markers for Type I TRCs. By recapitulating native human taste bud cell diversity and function, this organoid provides a tractable platform for studying human taste biology and dysfunction.
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A nuclear role for the contractile protein troponin I/UNC-27 in regulating muscle aging in C. elegans
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https://www.biorxiv.org/content/10.64898/2026.08.08.743652v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743652Cold Spring Harbor Laboratory2026-08-10
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Ferritinophagy Contributes to Iron Accumulation and Ferroptosis in FuchsEndothelial Corneal Dystrophy
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https://www.biorxiv.org/content/10.64898/2026.08.08.743691v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743691Cold Spring Harbor Laboratory2026-08-10
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Cellular senescence is associated with age-related loss of liver zonation and hepatocyte function
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https://www.biorxiv.org/content/10.64898/2026.08.08.743614v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743614Cold Spring Harbor Laboratory2026-08-10
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A ligand-property-guided computational framework for prioritizing de novo protein binders for small molecules
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https://www.biorxiv.org/content/10.64898/2026.08.08.743643v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743643Cold Spring Harbor Laboratory2026-08-10
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Ficd loss rescues motor impairments and reverses oligodendrocyte maturation deficits in a mouse model of spinocerebellar ataxia type 3
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https://www.biorxiv.org/content/10.64898/2026.08.07.743629v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743629Cold Spring Harbor Laboratory2026-08-10
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LiverDCP: A Disease-Cell-Protein Framework for Multi-scale Modeling of Disease Biology
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https://www.biorxiv.org/content/10.64898/2026.08.07.743628v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743628Cold Spring Harbor Laboratory2026-08-10
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From Diverse Prior Knowledge to Mechanistic Causal Network Using PSoup: A Case Study in Shoot Branching
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https://www.biorxiv.org/content/10.64898/2026.08.07.743620v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743620Cold Spring Harbor Laboratory2026-08-10
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Spatially Organized Tertiary Lymphoid Structures Emerge in Small Cell Lung Cancer and Associate with Improved Survival
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https://www.biorxiv.org/content/10.64898/2026.08.08.743663v1?rss=1
2026-08-10doi:10.64898/2026.08.08.743663Cold Spring Harbor Laboratory2026-08-10
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AI-Driven Computational Design of Peptide-Based WWP1 Inhibitors as Promising Therapeutic Agents Against Breast Cancer, Including Triple-Negative Subtype
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https://www.biorxiv.org/content/10.64898/2026.08.08.742959v1?rss=1
2026-08-10doi:10.64898/2026.08.08.742959Cold Spring Harbor Laboratory2026-08-10
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Glutamatergic systems in ctenophores
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https://www.biorxiv.org/content/10.64898/2026.08.09.743775v1?rss=1
2026-08-10doi:10.64898/2026.08.09.743775Cold Spring Harbor Laboratory2026-08-10
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MYCN-induced lineage infidelity initiates SHH medulloblastoma-like tumors outside the canonical lineage of origin
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https://www.biorxiv.org/content/10.64898/2026.08.07.743303v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743303Cold Spring Harbor Laboratory2026-08-10
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Cornichon receptors couple membrane adaptation to cargo selection during ER export.
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https://www.biorxiv.org/content/10.64898/2026.08.07.743479v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743479Cold Spring Harbor Laboratory2026-08-10
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Oral administration of dibenzoylmethane (DBM) prevents cognitive decline in a C9ORF72-mediated FTD mouse model
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https://www.biorxiv.org/content/10.64898/2026.08.07.743573v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743573Cold Spring Harbor Laboratory2026-08-10
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NET1 mRNA localization to the midbody is required for ARP2/3-dependent initiation of mitotic abscission
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https://www.biorxiv.org/content/10.64898/2026.08.07.743554v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743554Cold Spring Harbor Laboratory2026-08-10
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Mechanistic assessment of eDNA passive samplers: a case study with invasive freshwater bivalves
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https://www.biorxiv.org/content/10.64898/2026.08.07.743527v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743527Cold Spring Harbor Laboratory2026-08-10
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Re-evaluating Reported Pseudolysogeny in Phage T3: T3 and T7 Show Similar Propagation Responses to Nutrient Limitation and Media Switching
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https://www.biorxiv.org/content/10.64898/2026.08.07.743557v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743557Cold Spring Harbor Laboratory2026-08-10
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scROMA: batch-aware pathway-activity inference and a ground-truth simulation framework for single-cell transcriptomics
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https://www.biorxiv.org/content/10.64898/2026.08.07.743516v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743516Cold Spring Harbor Laboratory2026-08-10
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The ACTL domain of stomatal lineage bHLHs confers in vivo partner specificity
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https://www.biorxiv.org/content/10.64898/2026.08.07.743395v1?rss=1
2026-08-10doi:10.64898/2026.08.07.743395Cold Spring Harbor Laboratory2026-08-10