bioRxiv Subject Collection: Pharmacology And Toxicology
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This feed contains articles for bioRxiv Subject Collection "Pharmacology And Toxicology"
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Behavioural flexibility masks delayed costs of environmental instability
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https://www.biorxiv.org/content/10.64898/2026.08.04.742804v1?rss=1
2026-08-10doi:10.64898/2026.08.04.742804Cold Spring Harbor Laboratory2026-08-10
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Antinociceptive properties of an oral formulation of Δ9-tetrahydrocannabinol in aqueous 2-hydroxypropyl-β-cyclodextrin in female rats
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https://www.biorxiv.org/content/10.64898/2026.08.04.742765v1?rss=1
2026-08-10doi:10.64898/2026.08.04.742765Cold Spring Harbor Laboratory2026-08-10
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A foundational in vivo platform for predicting human health outcomes
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https://www.biorxiv.org/content/10.64898/2026.08.03.742611v1?rss=1
2026-08-09doi:10.64898/2026.08.03.742611Cold Spring Harbor Laboratory2026-08-09
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Vorapaxar and aripiprazole suppress hepatitis B virus replication through distinct host signaling pathways
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https://www.biorxiv.org/content/10.64898/2026.08.05.743121v1?rss=1
2026-08-09doi:10.64898/2026.08.05.743121Cold Spring Harbor Laboratory2026-08-09
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Adaptive experiments in high-dimensional feature spaces: A particle filtering approach
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https://www.biorxiv.org/content/10.64898/2026.08.03.741989v1?rss=1
2026-08-07doi:10.64898/2026.08.03.741989Cold Spring Harbor Laboratory2026-08-07
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The Privileged Link Between Number and Space: Day-old Chicks (Gallus gallus) Show Spatial-Numerical but Not Spatial-Quantity Associations
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https://www.biorxiv.org/content/10.64898/2026.08.03.742501v1?rss=1
2026-08-07doi:10.64898/2026.08.03.742501Cold Spring Harbor Laboratory2026-08-07
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ClinOracle: Hierarchical AI Prediction of Target Binding and Patient-Derived Functional Activity Across Diverse Therapeutic Targets
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https://www.biorxiv.org/content/10.64898/2026.08.02.742378v1?rss=1
2026-08-07doi:10.64898/2026.08.02.742378Cold Spring Harbor Laboratory2026-08-07
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Cryo-EM structural analysis of human TOP1 trapping by eight clinical anticancer drugs
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https://www.biorxiv.org/content/10.64898/2026.08.03.742490v1?rss=1
2026-08-07doi:10.64898/2026.08.03.742490Cold Spring Harbor Laboratory2026-08-07
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Socially transmitted knowledge of hibernation sites in bats
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https://www.biorxiv.org/content/10.64898/2026.08.06.743314v1?rss=1
2026-08-07doi:10.64898/2026.08.06.743314Cold Spring Harbor Laboratory2026-08-07
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Nosema ceranae infection disrupts nestmate recognition in honey bees
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https://www.biorxiv.org/content/10.64898/2026.08.02.742297v1?rss=1
2026-08-06doi:10.64898/2026.08.02.742297Cold Spring Harbor Laboratory2026-08-06
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Repeated within-session rule switching in the marmoset: a paradigm for tracking the dynamics of cognitive flexibility
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https://www.biorxiv.org/content/10.64898/2026.07.31.740852v1?rss=1
2026-08-06doi:10.64898/2026.07.31.740852Cold Spring Harbor Laboratory2026-08-06
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Hive position matters: spatial layout and hive colour impact forager traffic and drifting in Melipona quadrifasciata bees
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https://www.biorxiv.org/content/10.64898/2026.08.01.742195v1?rss=1
2026-08-06doi:10.64898/2026.08.01.742195Cold Spring Harbor Laboratory2026-08-06
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Multidimensional characterization of the physiological and behavioral effects of TCB-2 in mice
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https://www.biorxiv.org/content/10.64898/2026.08.01.742216v1?rss=1
2026-08-06doi:10.64898/2026.08.01.742216Cold Spring Harbor Laboratory2026-08-06
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QTrap-Enabled GERD Safety Analysis of Commercial Salsas
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https://www.biorxiv.org/content/10.64898/2026.07.31.742167v1?rss=1
2026-08-06doi:10.64898/2026.07.31.742167Cold Spring Harbor Laboratory2026-08-06
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Anatomical mapping and regulation of dopaminergic and octopaminergic neurons during temporal polyethism in the red harvester ant
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https://www.biorxiv.org/content/10.64898/2026.07.31.742069v1?rss=1
2026-08-06doi:10.64898/2026.07.31.742069Cold Spring Harbor Laboratory2026-08-06
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Behavioural type drives discovery and exploitation of anthropogenic resources
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https://www.biorxiv.org/content/10.64898/2026.07.31.742110v1?rss=1
2026-08-06doi:10.64898/2026.07.31.742110Cold Spring Harbor Laboratory2026-08-06
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Schema-Grounded Multitask Instruction Fine-tuning for Joint Biomedical Named Entity Recognition and Relation Extraction in Pharmacovigilance
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https://www.biorxiv.org/content/10.64898/2026.07.30.741807v1?rss=1
2026-08-06doi:10.64898/2026.07.30.741807Cold Spring Harbor Laboratory2026-08-06
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Resource depletion accelerates rate learning but not composition learning in patch foraging
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https://www.biorxiv.org/content/10.64898/2026.07.31.742044v1?rss=1
2026-08-05doi:10.64898/2026.07.31.742044Cold Spring Harbor Laboratory2026-08-05
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A sequence variation between two orthologues alters functional expression of the potassium channel Kesv of Ectocarpus siliculosus virus
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https://www.biorxiv.org/content/10.64898/2026.07.31.740523v1?rss=1
2026-08-05doi:10.64898/2026.07.31.740523Cold Spring Harbor Laboratory2026-08-05
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Akkermansia muciniphila prevents cadmium-induced cognitive impairment through gut microbiome mediated mechanisms
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https://www.biorxiv.org/content/10.64898/2026.07.31.740339v1?rss=1
2026-08-05doi:10.64898/2026.07.31.740339Cold Spring Harbor Laboratory2026-08-05
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Variation in CURE instruction and limitations of CURE studies undermine what can be concluded about CURE effects on student outcomes
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https://www.biorxiv.org/content/10.64898/2026.08.04.741794v1?rss=1
2026-08-05doi:10.64898/2026.08.04.741794Cold Spring Harbor Laboratory2026-08-05
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Non-instrumental information has limited effects on bet size in risky decisions
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https://www.biorxiv.org/content/10.64898/2026.07.30.741906v1?rss=1
2026-08-05doi:10.64898/2026.07.30.741906Cold Spring Harbor Laboratory2026-08-05
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Dorsal Striatum Silencing Attenuates Light Self-administration in Mice and Its Relevance to Digital technology-based Disorders
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https://www.biorxiv.org/content/10.64898/2026.07.31.742007v1?rss=1
2026-08-05doi:10.64898/2026.07.31.742007Cold Spring Harbor Laboratory2026-08-05
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Tunneling Effect with Time-Dependent Effective Potential Barrier: A Semiclassical (WKB) Reinterpretation of Drug Release Kinetics in Polymeric Nanocapsules
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https://www.biorxiv.org/content/10.64898/2026.07.30.741891v1?rss=1
0.999), while the rational (Hill) family remained poorly identified for all three systems despite the improved formula - favoring, by parsimony, the simpler exponential model throughout. Only G-NCA-1-5-FU remained non-identified with m free. A sensitivity check fixing m at the G-5-FU-derived value (m = 1.377) resolves this non-identifiability for G-NCA-1-5-FU at negligible cost in fit quality, consistent with a shared energy ratio for that system; the same constraint applied to NCA-1-5-FU, however, degrades its (already well-identified) fit by a factor of [~]4 in maximum residual; its own energy ratio (m = 1.188 {+/-} 0.007) differs from the shared value by [~]4{sigma}, a formally significant difference, so a single universal m is rejected for the complete set of systems studied. Reference values from the original multifractal study [2-4] and candidate extensions to further aptamer-functionalized nanocarrier systems [5-7] are also discussed. We discuss the implications of this treatment and its limits of validity, and point out paths for further empirical validation.
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Comparative analysis of transcriptomic liberality in 2,3,7,8-tetrachlorodibenzo-p-dioxin-exposed mouse liver RNA-Seq datasets
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https://www.biorxiv.org/content/10.64898/2026.07.30.741944v1?rss=1
2026-08-05doi:10.64898/2026.07.30.741944Cold Spring Harbor Laboratory2026-08-05
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Peripheral CB1R Blockade Suppresses AKI-to-CKD Maladaptive Repair
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https://www.biorxiv.org/content/10.64898/2026.07.31.741993v1?rss=1
2026-08-05doi:10.64898/2026.07.31.741993Cold Spring Harbor Laboratory2026-08-05
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Closed-loop robotic interactions reveal dynamic social filtering in schooling fish
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https://www.biorxiv.org/content/10.64898/2026.08.03.742553v1?rss=1
2026-08-05doi:10.64898/2026.08.03.742553Cold Spring Harbor Laboratory2026-08-05
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Tracing information propagation in fish schools with a conditioned escape response
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https://www.biorxiv.org/content/10.64898/2026.08.04.742699v1?rss=1
2026-08-05doi:10.64898/2026.08.04.742699Cold Spring Harbor Laboratory2026-08-05
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NC4touch: An open-source networked touchscreen apparatus for rodent behavioral testing
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https://www.biorxiv.org/content/10.64898/2026.07.30.741621v1?rss=1
2026-08-04doi:10.64898/2026.07.30.741621Cold Spring Harbor Laboratory2026-08-04
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Opposing influences of sensory and response history in larval zebrafish
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https://www.biorxiv.org/content/10.64898/2026.07.30.741669v1?rss=1
2026-08-04doi:10.64898/2026.07.30.741669Cold Spring Harbor Laboratory2026-08-04