bioRxiv Subject Collection: Genetics Plant Biology
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This feed contains articles for bioRxiv Subject Collection "Genetics Plant Biology"
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Activity-level evaluation of DNA transfer to stockings: comparisonof HaloGen with simplified contributor-based approaches
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https://www.biorxiv.org/content/10.64898/2026.09.04.749444v1?rss=1
2026-09-09doi:10.64898/2026.09.04.749444Cold Spring Harbor Laboratory2026-09-09
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mRNA editing of the Alzheimer's risk gene APOE
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https://www.biorxiv.org/content/10.64898/2026.09.03.749263v1?rss=1
90%) C to U editing of APOE4 mRNA at the AE4 but not AE2 site, with lower (<10%) C to T editing of genomic DNA at the AE4 site by mouse, but not human, APOBEC1. Furthermore, interrogation of proteomic datasets revealed up to 4% of non-genomically encoded APOE peptides in human plasma, indicating that the edited APOE transcripts are functional in vivo. These data suggest that APOE mRNA is subject to RNA editing that interconverts the different allelic forms of APOE.
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PRDM9 Alleles Guide Distinct Patterns of Recombination Localization in Atlantic Salmon
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https://www.biorxiv.org/content/10.64898/2026.09.03.749262v1?rss=1
2026-09-09doi:10.64898/2026.09.03.749262Cold Spring Harbor Laboratory2026-09-09
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Transcription-Coupled Chromatin Reinforcement Maintains the Mature Cardiomyocyte State
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https://www.biorxiv.org/content/10.64898/2026.09.04.749300v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749300Cold Spring Harbor Laboratory2026-09-08
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Genetic trans-effects link triglyceride-rich lipoproteins to blood pressure
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https://www.biorxiv.org/content/10.64898/2026.09.04.749549v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749549Cold Spring Harbor Laboratory2026-09-08
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Bundling Alleles Within Haplotype Blocks Improves QTL Detection Under Allelic Heterogeneity
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https://www.biorxiv.org/content/10.64898/2026.09.04.749340v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749340Cold Spring Harbor Laboratory2026-09-08
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Synonymous HTT CAA/CCA-loss variants associated with early Huntington disease onset enhance toxicity beyond somatic instability
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https://www.biorxiv.org/content/10.64898/2026.09.03.749261v1?rss=1
CCA-loss > CAA-loss > canonical HTT) in both wildtype and MSH3 knockout cells. Furthermore, the CAA/CCA-loss variant generates elevated levels of repeat-associated non-AUG (RAN) translation products. In HEK293-based cellular models, these results suggest that the disease-accelerating effects of HTT CAA/CCA-loss variants involve intrinsic properties of the altered sequence context, highlighting the importance of understanding sequence-specific mechanisms in HD pathogenesis beyond polyglutamine length and somatic instability.
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Cell Geometry and Junction Arrangement Define the Mechanical Robustness of Plant Tissues
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https://www.biorxiv.org/content/10.64898/2026.09.07.749888v1?rss=1
2026-09-08doi:10.64898/2026.09.07.749888Cold Spring Harbor Laboratory2026-09-08
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Polar auxin transport regulates initial auxin patterning and polar nuclear migration during lateral root initiation
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https://www.biorxiv.org/content/10.64898/2026.09.04.749482v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749482Cold Spring Harbor Laboratory2026-09-08
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A cross-kingdom interactome predicted by AlphaFold3 reveals a DNF2-centered interface required for symbiotic accommodation
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https://www.biorxiv.org/content/10.64898/2026.09.04.749384v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749384Cold Spring Harbor Laboratory2026-09-08
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Base editing of EIF4E creates novel resistance alleles against bymoviruses in winter barley
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https://www.biorxiv.org/content/10.64898/2026.09.04.749431v1?rss=1
2026-09-08doi:10.64898/2026.09.04.749431Cold Spring Harbor Laboratory2026-09-08
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ACHT2 deactivates carbon assimilation during light-dark transition
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https://www.biorxiv.org/content/10.64898/2026.09.02.748655v1?rss=1
2026-09-07doi:10.64898/2026.09.02.748655Cold Spring Harbor Laboratory2026-09-07
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Dynamic Filament Assembly Regulates the Prolyl Aminopeptidase Activity of Plant Immune Protein DM3
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https://www.biorxiv.org/content/10.64898/2026.09.03.749275v1?rss=1
2026-09-07doi:10.64898/2026.09.03.749275Cold Spring Harbor Laboratory2026-09-07
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The PP2A phosphatase associates with the Arabidopsis TRAPPII tethering complex and dephosphorylates a TRAPPII-derived phosphopeptide in vitro
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https://www.biorxiv.org/content/10.64898/2026.09.03.749138v1?rss=1
2026-09-07doi:10.64898/2026.09.03.749138Cold Spring Harbor Laboratory2026-09-07
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BOTANIC-1: a series of long-context plant genomic foundation models in the agentic era
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https://www.biorxiv.org/content/10.64898/2026.09.04.749355v1?rss=1
2026-09-07doi:10.64898/2026.09.04.749355Cold Spring Harbor Laboratory2026-09-07
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Continuous monitoring of deficit irrigation in avocado across two contrasting rainfall years using sensor networks, telemetry, and machine learning
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https://www.biorxiv.org/content/10.64898/2026.09.03.745400v1?rss=1
2026-09-07doi:10.64898/2026.09.03.745400Cold Spring Harbor Laboratory2026-09-07
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Endogenous and environmentally modulated leaf shape plasticity in Boquila trifoliolata: how good is the evidence for mimicry?
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https://www.biorxiv.org/content/10.64898/2026.09.03.749126v1?rss=1
2026-09-07doi:10.64898/2026.09.03.749126Cold Spring Harbor Laboratory2026-09-07
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Provitamin A maize inbred lines exhibit resistance to multiple foliar diseases under laboratory and field conditions
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https://www.biorxiv.org/content/10.64898/2026.09.03.749191v1?rss=1
2026-09-07doi:10.64898/2026.09.03.749191Cold Spring Harbor Laboratory2026-09-07
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Duckweeds as Multiplexable Plant Models for Exploring Abiotic Stress Responses
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https://www.biorxiv.org/content/10.64898/2026.09.03.749270v1?rss=1
2026-09-07doi:10.64898/2026.09.03.749270Cold Spring Harbor Laboratory2026-09-07
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Genetic dissection of a Solanum elaeagnifolium tertiary genepool introgression associated with 4-O-caffeoylquinic acid accumulation in eggplant
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https://www.biorxiv.org/content/10.64898/2026.09.04.749343v1?rss=1
2026-09-07doi:10.64898/2026.09.04.749343Cold Spring Harbor Laboratory2026-09-07
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Sexual dimorphism of autism-like phenotypes in microglial eIF4E overexpression mice
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https://www.biorxiv.org/content/10.64898/2026.09.03.748596v1?rss=1
2026-09-07doi:10.64898/2026.09.03.748596Cold Spring Harbor Laboratory2026-09-07
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Phantom genetic nurture: assortative mating accounts for most of the apparent association between parental genotypes and childhood cognitive performance
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https://www.biorxiv.org/content/10.64898/2026.09.01.748516v1?rss=1
2026-09-06doi:10.64898/2026.09.01.748516Cold Spring Harbor Laboratory2026-09-06
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Spatiotemporal pectin remodelling, glycoproteins, and LEA proteins maintain cell wall integrity during desiccation and rehydration in Ramonda serbica
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https://www.biorxiv.org/content/10.64898/2026.09.03.749093v1?rss=1
2026-09-06doi:10.64898/2026.09.03.749093Cold Spring Harbor Laboratory2026-09-06
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Conditions and properties of non-Mendelian transmission of recombinants in female meiosis
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https://www.biorxiv.org/content/10.64898/2026.09.01.748656v1?rss=1
2026-09-05doi:10.64898/2026.09.01.748656Cold Spring Harbor Laboratory2026-09-05
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A large-effect locus on chromosome 4 underlies circadian feeding rhythmicity in pigs
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https://www.biorxiv.org/content/10.64898/2026.09.01.748529v1?rss=1
2026-09-04doi:10.64898/2026.09.01.748529Cold Spring Harbor Laboratory2026-09-04
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Wolf microevolution in the melting pot: range expansion, population sympatry, dynamic mosaic admixture zone and asymmetric gene flow
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https://www.biorxiv.org/content/10.64898/2026.09.02.748779v1?rss=1
2026-09-04doi:10.64898/2026.09.02.748779Cold Spring Harbor Laboratory2026-09-04
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Evidence for a regulatory role of the evolutionarily conserved sequence complementarity between tRNAs
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https://www.biorxiv.org/content/10.64898/2026.09.02.748885v1?rss=1
2026-09-04doi:10.64898/2026.09.02.748885Cold Spring Harbor Laboratory2026-09-04
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EDTP Loss of Function Impairs Longevity and Reproduction
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https://www.biorxiv.org/content/10.64898/2026.08.31.748413v1?rss=1
2026-09-04doi:10.64898/2026.08.31.748413Cold Spring Harbor Laboratory2026-09-04
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Implication of a rare variant in OPA1 in Cardiac Pathophysiology: From Cristae Remodelling to Contractile Dysfunction
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https://www.biorxiv.org/content/10.64898/2026.08.31.748193v1?rss=1
T (p.Pro188Leu), was identified in a DCM patient, which is absent in 100 healthy controls as well as in the 1000 Genomes, IndiGenomes and GenomeAsia 100k databases while it showed very low MAF (0.000069) in GnomAD. Structural modelling predicted the variant to be highly deleterious and revealed marked conformational distortion of the mutant protein (RMSD = 3.5 Angstrom). Molecular docking further demonstrated enhanced accessibility of mutant OPA1 to mitochondrial protease OMA1, suggesting increased OPA1 proteolytic processing and a consequent increase in mitochondrial fragmentation. Functional analysis in stable H9C2 cardiomyoblast cells, demonstrated significantly reduced OPA1 protein expression, extensive mitochondrial fragmentation in mutant-OPA1 expressing cells. The mutant protein caused significant reduction in mitochondrial membrane potential, ATP generation, and oxygen consumption rate (OCR), together with elevated cytosolic Calcium and reactive oxygen species (ROS) levels. qRT-PCR analysis further revealed depletion in mtDNA copy number and increased in expression of intrinsic apoptotic markers Caspase3, 9 and Bax/Bcl-2 ratio. The above findings collectively highlighted the significant impact of the OPA1 mutation on mitochondrial dynamics and cellular health, suggesting a significant correlation with the pathogenesis of DCM. Collectively, these findings suggest that OPA1-mediated mitochondrial dysfunction represents a potential therapeutic avenue for the management of DCM.
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The evolutionarily conserved EHMT1/G9a histone methyltransferase family regulates sleep maintenance through ROS homeostasis in insulin-producing cells
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https://www.biorxiv.org/content/10.64898/2026.08.28.747754v1?rss=1
2026-09-03doi:10.64898/2026.08.28.747754Cold Spring Harbor Laboratory2026-09-03