bioRxiv Channel: <? echo $gname; ?> https://biorxiv.org This feed contains articles for bioRxiv Channel "" bioRxiv bioRxiv https://biorxiv.org <![CDATA[ A DNA-based optical nanosensor for in vivo imaging of acetylcholine in the peripheral nervous system ]]> https://biorxiv.org/cgi/content/short/2020.07.06.189696v1?rss=1" Xia, J. Yang, H. Mu, M. Micovic, N. Poskanzer, K. E. Monaghan, J. R. Clark, H. A. 2020-07-06 doi:10.1101/2020.07.06.189696 Cold Spring Harbor Laboratory Press 2020-07-06 <![CDATA[ Optogenetic Stimulation of Pancreatic Function via Vagal Cholinergic Axons ]]> https://biorxiv.org/cgi/content/short/2019.12.21.885970v1?rss=1" Fontaine, A. K. Ramirez, D. G. Littich, S. F. Piscopio, R. Kravets, V. Caldwell, J. H. Weir, R. F. Benninger, R. K. 2019-12-23 doi:10.1101/2019.12.21.885970 Cold Spring Harbor Laboratory Press 2019-12-23 <![CDATA[ Selective Modulation of Heart and Respiration by Optical Control of Vagus Nerve Axons Innervating the Heart ]]> https://biorxiv.org/cgi/content/short/2020.06.26.173898v1?rss=1" Fontaine, A. K. Futia, G. L. Rajendran, P. S. Littich, S. Mizoguchi, N. Shivkumar, K. Ardell, J. L. Restrepo, D. Caldwell, J. H. Gibson, E. A. Weir, R. F. 2020-06-29 doi:10.1101/2020.06.26.173898 Cold Spring Harbor Laboratory Press 2020-06-29 <![CDATA[ A spatially-tracked single cell transcriptomics map of neuronal networks in the intrinsic cardiac nervous system ]]> https://biorxiv.org/cgi/content/short/2020.07.29.227090v1?rss=1" Moss, A. Robbins, S. Achanta, S. Kuttippurathu, L. Turick, S. Nieves, S. Hanna, P. Smith, E. H. Hoover, D. B. Chen, J. Cheng, Z. Ardell, J. L. Shivkumar, K. Schwaber, J. S. Vadigepalli, R. 2020-07-30 doi:10.1101/2020.07.29.227090 Cold Spring Harbor Laboratory Press 2020-07-30 <![CDATA[ 3D single cell scale anatomical map of sex-dependent variability of the rat intrinsic cardiac nervous system ]]> https://biorxiv.org/cgi/content/short/2020.07.29.227538v1?rss=1" Leung, C. Robbins, S. Moss, A. Heal, M. Osanlouy, M. Christie, R. Farahani, N. Monteith, C. Chen, J. Hunter, P. Tappan, S. Vadigepalli, R. Cheng, Z. Schwaber, J. S. 2020-07-30 doi:10.1101/2020.07.29.227538 Cold Spring Harbor Laboratory Press 2020-07-30 <![CDATA[ Evidence of Superior and Inferior Sinoatrial Nodes in the Mammalian Heart ]]> https://biorxiv.org/cgi/content/short/2020.06.18.159939v1?rss=1" Brennan, J. A. Chen, Q. Gams, A. Dyavanapalli, J. Mendelowitz, D. Peng, W. Efimov, I. R. 2020-06-20 doi:10.1101/2020.06.18.159939 Cold Spring Harbor Laboratory Press 2020-06-20 <![CDATA[ Combinatorial transcriptional profiling of mouse and human enteric neurons identifies shared and disparate subtypes in situ. ]]> https://biorxiv.org/cgi/content/short/2020.07.03.187211v1?rss=1" View larger version (40K): org.highwire.dtl.DTLVardef@1b41277org.highwire.dtl.DTLVardef@12856feorg.highwire.dtl.DTLVardef@1674dadorg.highwire.dtl.DTLVardef@11ca1c8_HPS_FORMAT_FIGEXP M_FIG Graphical Abstract C_FIG ]]> May-Zhang, A. A. Tycksen, E. Southard-Smith, A. N. Deal, K. K. Benthal, J. T. Buehler, D. P. Adam, M. Simmons, A. J. Monaghan, J. R. Matlock, B. K. Flaherty, D. K. Potter, S. Lau, K. S. Southard-Smith, E. M. 2020-07-04 doi:10.1101/2020.07.03.187211 Cold Spring Harbor Laboratory Press 2020-07-04 <![CDATA[ A comprehensive, FAIR file format for neuroanatomical structure modeling ]]> https://biorxiv.org/cgi/content/short/2020.09.22.306670v1?rss=1" Sullivan, A. E. Tappan, S. J. Angstman, P. J. Rodriguez, A. Thomas, G. C. Hoppes, D. M. Abdul-Karim, M.-A. Heal, M. L. Glaser, J. R. 2020-09-22 doi:10.1101/2020.09.22.306670 Cold Spring Harbor Laboratory Press 2020-09-22 <![CDATA[ Comprehensive Integrated Anatomical And Molecular Atlas Of Rodent Intrinsic Cardiac Nervous System ]]> https://biorxiv.org/cgi/content/short/661033v1?rss=1" Achanta, S. Gorky, J. M. Leung, C. Moss, A. Robbins, S. Eisenman, L. Chen, J. Tappan, S. Heal, M. Farhani, N. Huffman, T. Cheng, Z. Vadigepalli, R. Schwaber, J. S. 2019-06-05 doi:10.1101/661033 Cold Spring Harbor Laboratory Press 2019-06-05 <![CDATA[ Input-output signal processing plasticity of vagal motorneurons in response to cardiac ischemic injury ]]> https://biorxiv.org/cgi/content/short/2020.08.09.242792v1?rss=1" Gorky, J. M. Moss, A. Balycheva, M. Vadigepalli, R. Schwaber, J. 2020-08-10 doi:10.1101/2020.08.09.242792 Cold Spring Harbor Laboratory Press 2020-08-10 <![CDATA[ High-density Neural Recordings from Feline Sacral Dorsal Root Ganglia with Thin-film Array ]]> https://biorxiv.org/cgi/content/short/2020.07.14.199653v1?rss=1" Sperry, Z. J. Na, K. Jun, J. Madden, L. R. Socha, A. Yoon, E. Seymour, J. P. Bruns, T. M. 2020-07-15 doi:10.1101/2020.07.14.199653 Cold Spring Harbor Laboratory Press 2020-07-15 <![CDATA[ Novel diamond shuttle to deliver flexible bioelectronics with reduced tissue compression ]]> https://biorxiv.org/cgi/content/short/435800v1?rss=1" Na, K. Sperry, Z. J. Lu, J. Voeroeslakos, M. Parizi, S. S. Bruns, T. M. Yoon, E. Seymour, J. P. 2018-10-16 doi:10.1101/435800 Cold Spring Harbor Laboratory Press 2018-10-16 <![CDATA[ Multi-channel intraneural vagus nerve recordings with a novel high-density carbon fiber microelectrode array ]]> https://biorxiv.org/cgi/content/short/2020.05.15.098301v1?rss=1" Jiman, A. A. Ratze, D. C. Welle, E. J. Patel, P. R. Richie, J. M. Bottorff, E. C. Seymour, J. P. Chestek, C. A. Bruns, T. M. 2020-05-16 doi:10.1101/2020.05.15.098301 Cold Spring Harbor Laboratory Press 2020-05-16 <![CDATA[ Machine learning prediction of emesis and gastrointestinal state in ferrets ]]> https://biorxiv.org/cgi/content/short/607242v1?rss=1" 80%). The present study is the first demonstration of machine learning algorithms to detect the physiological state of the stomach and onset of retching and could provide insight into methodologies to treat GI diseases and control symptoms such as nausea and vomiting. ]]> Nanivadekar, A. C. Miller, D. M. Fulton, S. Wong, L. Ogren, J. Chitnis, G. McLaughlin, B. Zhai, S. Fisher, L. E. Yates, B. J. Horn, C. C. 2019-04-12 doi:10.1101/607242 Cold Spring Harbor Laboratory Press 2019-04-12 <![CDATA[ A neuroskeletal atlas of the mouse limb ]]> https://biorxiv.org/cgi/content/short/2020.09.18.303958v1?rss=1" Lorenz, M. R. Brazill, J. M. Beeve, A. Shen, I. Scheller, E. L. 2020-09-19 doi:10.1101/2020.09.18.303958 Cold Spring Harbor Laboratory Press 2020-09-19 <![CDATA[ Lung at a Glance: an integrative web toolset of lung ontology, imaging and single cell omics ]]> https://biorxiv.org/cgi/content/short/2020.06.19.161851v1?rss=1" Du, Y. Ouyang, W. Kitzmiller, J. Guo, M. Zhao, S. Whitsett, J. A. Xu, Y. 2020-06-20 doi:10.1101/2020.06.19.161851 Cold Spring Harbor Laboratory Press 2020-06-20 <![CDATA[ Identification of the lymphangioleiomyomatosis cell and its uterine origin ]]> https://biorxiv.org/cgi/content/short/784199v1?rss=1" Guo, M. Yu, J. J. Perl, A. K. Wikenheiser-Brokamp, K. A. Riccetti, M. Zhang, E. Y. Sudha, P. Adam, M. Potter, A. Kopras, E. J. Giannikou, K. Potter, S. S. Sherman, S. Hammes, S. R. Kwiatkowski, D. J. Whitsett, J. A. McCormack, F. X. Xu, Y. 2019-10-08 doi:10.1101/784199 Cold Spring Harbor Laboratory Press 2019-10-08 <![CDATA[ Imaging fascicular organization of peripheral nerves with fast neural Electrical Impedance Tomography (EIT) ]]> https://biorxiv.org/cgi/content/short/2020.06.04.133843v1?rss=1" Ravagli, E. Mastitkaya, S. Thompson, N. Iacoviello, F. Shearing, P. R. Perkins, J. Gourine, A. V. Aristovich, K. Holder, D. 2020-06-05 doi:10.1101/2020.06.04.133843 Cold Spring Harbor Laboratory Press 2020-06-05 <![CDATA[ Innervation and Neuronal Control of the Mammalian Sinoatrial Node: A Comprehensive Atlas ]]> https://biorxiv.org/cgi/content/short/2020.10.28.359109v1?rss=1" Hanna, P. Dacey, M. J. Brennan, J. Moss, A. Robbins, S. Achanta, S. Biscola, N. P. Swid, M. A. Rajendran, P. S. Mori, S. Hadaya, J. Smith, E. H. Peirce, S. G. Chen, J. Havton, L. A. Cheng, Z. Vadigepalli, R. Schwaber, J. Lux, R. L. Efimov, I. Tompkins, J. D. Hoover, D. B. Ardell, J. L. Shivkumar, K. 2020-10-29 doi:10.1101/2020.10.28.359109 Cold Spring Harbor Laboratory Press 2020-10-29 <![CDATA[ Sex-specific classification of drug-induced Torsade de Pointes susceptibility using cardiac simulations and machine learning ]]> https://biorxiv.org/cgi/content/short/2020.10.26.352740v1?rss=1" Fogli Iseppe, A. Ni, H. Zhu, S. Zhang, X. Coppini, R. Yang, P.-C. Srivatsa, U. Clancy, C. E. Edwards, A. G. Morotti, S. Grandi, E. 2020-10-27 doi:10.1101/2020.10.26.352740 Cold Spring Harbor Laboratory Press 2020-10-27 <![CDATA[ Preliminary Minimum Reporting Requirements for Reporting In-Vivo Neural Interface Research: I. Implantable Neural Interfaces ]]> https://biorxiv.org/cgi/content/short/2020.11.18.375741v1?rss=1" Eiber, C. D. Delbeke, J. Cardoso, J. de Neeling, M. John, S. Lee, C. W. Skefos, J. Sun, A. Prodanov, D. McKinney, Z. 2020-11-20 doi:10.1101/2020.11.18.375741 Cold Spring Harbor Laboratory Press 2020-11-20 <![CDATA[ Automatic Assessment of Human Gastric Motility and Emptying from Dynamic 3D Magnetic Resonance Imaging ]]> https://biorxiv.org/cgi/content/short/2020.12.11.421743v1?rss=1" Lu, K.-H. Liu, Z. Jaffey, D. Wo, J. Mosier, K. Cao, J. Wang, X. Powley, T. L. 2020-12-11 doi:10.1101/2020.12.11.421743 Cold Spring Harbor Laboratory Press 2020-12-11 <![CDATA[ Quantitative cross-species translators of cardiac myocyte electrophysiology: model training, experimental validation, and applications ]]> https://biorxiv.org/cgi/content/short/2020.12.17.423297v1?rss=1" Morotti, S. Liu, C. Hegyi, B. Ni, H. Fogli Iseppe, A. Wang, L. Ripplinger, C. M. Bers, D. M. Edwards, A. G. Grandi, E. 2020-12-18 doi:10.1101/2020.12.17.423297 Cold Spring Harbor Laboratory Press 2020-12-18 <![CDATA[ Functional Vagotopy in the Cervical Vagus Nerve of the Domestic Pig: Implications for Vagus Nerve Stimulation ]]> https://biorxiv.org/cgi/content/short/856989v1?rss=1" Settell, M. L. Knudsen, B. E. Dingle, A. M. McConico, A. L. Nicolai, E. N. Trevathan, J. K. Ross, E. K. Pelot, N. A. Grill, W. M. Gustafson, K. J. Shoffstall, A. J. Williams, J. C. Zeng, W. Poore, S. O. Populin, L. C. Suminski, A. J. Ludwig, K. A. 2019-11-27 doi:10.1101/856989 Cold Spring Harbor Laboratory Press 2019-11-27 <![CDATA[ In vivo visualization of pig vagus nerve 'vagotopy' using ultrasound ]]> https://biorxiv.org/cgi/content/short/2020.12.24.424256v1?rss=1" Settell, M. L. Kasole, M. Skubal, A. C. Knudsen, B. E. Nicolai, E. N. Huang, C. Zhou, C. Trevathan, J. K. Pelot, N. A. Grill, W. M. Upadhye, A. Kolluru, C. Shoffstall, A. J. Williams, J. C. Suminski, A. J. Chen, S. Ludwig, K. A. 2020-12-24 doi:10.1101/2020.12.24.424256 Cold Spring Harbor Laboratory Press 2020-12-24 <![CDATA[ Sources of Off-Target Effects of Vagus Nerve Stimulation Using the Helical Clinical Lead in Domestic Pigs ]]> https://biorxiv.org/cgi/content/short/2020.01.15.907246v1?rss=1" 10 mA) and human studies (<250 {micro}A). After removing muscle-generated artifacts, ENG signals with post-stimulus latencies consistent with A{delta}- and B-fibers occurred in only a small subset of animals, and these signals had similar thresholds to those that caused bradycardia. By identifying specific neuroanatomical pathways that cause off-target effects and characterizing the stimulation dose-response curves for on- and off-target effects, we hope to guide interpretation and optimization of clinical VNS. ]]> Nicolai, E. N. Settell, M. L. Knudsen, B. E. McConico, A. L. Gosink, B. A. Trevathan, J. K. Baumgart, I. W. Ross, E. K. Pelot, N. A. Grill, W. M. Gustafson, K. J. Shoffstall, A. J. Williams, J. C. Ludwig, K. A. 2020-01-15 doi:10.1101/2020.01.15.907246 Cold Spring Harbor Laboratory Press 2020-01-15 <![CDATA[ Sharpened and mechanically robust carbon fiber electrode arrays for neural interfacing ]]> https://biorxiv.org/cgi/content/short/2021.01.21.427697v1?rss=1" Welle, E. J. Woods, J. E. Jiman, A. A. Richie, J. M. Bottorff, E. C. Ouyang, Z. Seymour, J. P. Patel, P. R. Bruns, T. M. Chestek, C. A. 2021-01-22 doi:10.1101/2021.01.21.427697 Cold Spring Harbor Laboratory Press 2021-01-22 <![CDATA[ Selective stimulation of the ferret abdominal vagus nerve with multi-contact nerve cuff electrodes ]]> https://biorxiv.org/cgi/content/short/2021.02.19.431879v1?rss=1" Shulgach, J. A. Beam, D. W. Nanivadekar, A. C. Miller, D. M. Fulton, S. Sciullo, M. Ogren, J. Wong, L. McLaughlin, B. Yates, B. J. Horn, C. Fisher, L. 2021-02-20 doi:10.1101/2021.02.19.431879 Cold Spring Harbor Laboratory Press 2021-02-20 <![CDATA[ The SPARC DRC: Building a resource for the autonomic nervous system community ]]> https://biorxiv.org/cgi/content/short/2021.04.01.438136v1?rss=1" Osanlouy, M. Bandrowski, A. de Bono, B. Brooks, D. Cassara, A. M. Christie, R. Ebrahimi, N. Gillespie, T. Grethe, J. S. Guercio, L. A. Heal, M. Lin, M. Kuster, N. Martone, M. E. Neufeld, E. Nickerson, D. P. Soltani, E. G. Tappan, S. Wagenaar, J. B. Zhuang, K. Hunter, P. J. 2021-04-04 doi:10.1101/2021.04.01.438136 Cold Spring Harbor Laboratory Press 2021-04-04 <![CDATA[ High-density spinal cord stimulation selectively activates lower urinary tract afferents ]]> https://biorxiv.org/cgi/content/short/2021.04.30.442206v1?rss=1" Jantz, M. K. Gopinath, C. Kumar, R. Chin, C. Wong, L. Ogren, J. I. Fisher, L. E. McLaughlin, B. L. Gaunt, R. A. 2021-05-01 doi:10.1101/2021.04.30.442206 Cold Spring Harbor Laboratory Press 2021-05-01 <![CDATA[ SPARC Data Structure: Rationale and Design of a FAIR Standard for Biomedical Research Data ]]> https://biorxiv.org/cgi/content/short/2021.02.10.430563v1?rss=1" Bandrowski, A. Grethe, J. S. Pilko, A. Gillespie, T. H. Pine, G. Patel, B. Surles-Zeiglera, M. Martone, M. E. 2021-02-10 doi:10.1101/2021.02.10.430563 Cold Spring Harbor Laboratory Press 2021-02-10 <![CDATA[ Fascicles split or merge every ~560 microns within the human cervical vagus nerve ]]> https://biorxiv.org/cgi/content/short/2021.11.09.467343v1?rss=1" Upadhye, A. R. Kolluru, C. Druschel, L. Al Lababidi, L. Ahmad, S. Menendez, D. Buyukcelik, O. N. Settell, M. L. Jenkins, M. W. Wilson, D. Zhang, J. Tatsuoka, C. Grill, W. M. Pelot, N. A. Ludwig, K. Gustafson, K. J. Shoffstall, A. J. 2021-11-11 doi:10.1101/2021.11.09.467343 Cold Spring Harbor Laboratory Press 2021-11-11 <![CDATA[ Comparative transcriptomics reveal highly conserved regional programs between porcine and human colonic enteric nervous system ]]> https://biorxiv.org/cgi/content/short/2022.02.24.480770v1?rss=1" 90% of their transcriptomic responses to vagal nerve stimulation (VNS), suggesting that p-pC and p-dC could serve as predictors in translational studies. The conserved programs specific for inflammatory modulation were displayed in porcine with VNS. This study provides a valuable transcriptomic resource for understanding of human colonic functions and neuromodulation using porcine model. ]]> Li, T. Morselli, M. Su, T. Mulugeta, M. Larauche, M. Tache, Y. Yuan, P.-Q. 2022-02-25 doi:10.1101/2022.02.24.480770 Cold Spring Harbor Laboratory Press 2022-02-25