bioRxiv Subject Collection: Synthetic Biology
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This feed contains articles for bioRxiv Subject Collection "Synthetic Biology"
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Chimeric Induced Cooperativity Opens the Design Space of Eukaryotic Gene Regulation
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https://www.biorxiv.org/content/10.64898/2026.08.28.747696v1?rss=1
2026-08-28doi:10.64898/2026.08.28.747696Cold Spring Harbor Laboratory2026-08-28
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Dynamic Control of Prokaryotic Chromosome Ploidy Rewires Metabolic Networks to Enhance Product Biosynthesis
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https://www.biorxiv.org/content/10.64898/2026.08.27.747416v1?rss=1
2026-08-28doi:10.64898/2026.08.27.747416Cold Spring Harbor Laboratory2026-08-28
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Establishing Design Principles for CRISPR-Cas Antifungals in Candida albicans
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https://www.biorxiv.org/content/10.64898/2026.08.27.747665v1?rss=1
2026-08-28doi:10.64898/2026.08.27.747665Cold Spring Harbor Laboratory2026-08-28
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Timing of metabolomics-driven supplementation strategies affects protein expression in E. coli-based cell-free expression systems
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https://www.biorxiv.org/content/10.64898/2026.08.26.746766v1?rss=1
2026-08-27doi:10.64898/2026.08.26.746766Cold Spring Harbor Laboratory2026-08-27
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DIPTAR: A synthetic biology platform for functional interrogation of protein degradation
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https://www.biorxiv.org/content/10.64898/2026.08.26.747229v1?rss=1
2026-08-27doi:10.64898/2026.08.26.747229Cold Spring Harbor Laboratory2026-08-27
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Programmable De Novo Design of Mesoporous Protein Crystal Frameworks
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https://www.biorxiv.org/content/10.64898/2026.08.25.747085v1?rss=1
2026-08-26doi:10.64898/2026.08.25.747085Cold Spring Harbor Laboratory2026-08-26
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Lanthanide protein biosensors with a single ion-binding site
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https://www.biorxiv.org/content/10.64898/2026.08.25.747157v1?rss=1
2026-08-26doi:10.64898/2026.08.25.747157Cold Spring Harbor Laboratory2026-08-26
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A Mammalian High-Throughput Screen for AI-Designed Peptide-Guided Protein Degraders
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https://www.biorxiv.org/content/10.64898/2026.08.24.746873v1?rss=1
2026-08-26doi:10.64898/2026.08.24.746873Cold Spring Harbor Laboratory2026-08-26
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ORB-TXTL: cell-free expression of membrane proteins on lipid bilayer-coated beads
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https://www.biorxiv.org/content/10.64898/2026.08.26.747166v1?rss=1
2026-08-26doi:10.64898/2026.08.26.747166Cold Spring Harbor Laboratory2026-08-26
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Unobserved Sequence Space Has Many Functional Proteins
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https://www.biorxiv.org/content/10.64898/2026.08.24.746828v1?rss=1
2026-08-26doi:10.64898/2026.08.24.746828Cold Spring Harbor Laboratory2026-08-26
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Essential function of femaleless in female gametogenesis controls gene drive spread in Anopheles gambiae
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https://www.biorxiv.org/content/10.64898/2026.08.22.746406v1?rss=1
2026-08-24doi:10.64898/2026.08.22.746406Cold Spring Harbor Laboratory2026-08-24
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Synthetic transcriptional control in the malaria parasite Plasmodium falciparum
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https://www.biorxiv.org/content/10.64898/2026.08.21.744319v1?rss=1
2026-08-24doi:10.64898/2026.08.21.744319Cold Spring Harbor Laboratory2026-08-24
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Plant Bioengineering Atlas: A Knowledge Graph of Genes, DNA Constructs, and Plant Traits.
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https://www.biorxiv.org/content/10.64898/2026.08.21.746270v1?rss=1
2026-08-24doi:10.64898/2026.08.21.746270Cold Spring Harbor Laboratory2026-08-24
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Programmable genetic control of tumor-colonizing Bifidobacterium longum for intratumoral therapeutic delivery and biocontainment
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https://www.biorxiv.org/content/10.64898/2026.08.12.744520v1?rss=1
2026-08-17doi:10.64898/2026.08.12.744520Cold Spring Harbor Laboratory2026-08-17
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Active Learning Enables Efficient Directed Evolution of a Far-Red Fluorescent Protein with Minimal Experimental Data
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https://www.biorxiv.org/content/10.64898/2026.08.12.744534v1?rss=1
View larger version (11K):
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DNA-GUARD: molecular access control as a physical security layer for DNA data storage
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https://www.biorxiv.org/content/10.64898/2026.08.12.744375v1?rss=1
2026-08-17doi:10.64898/2026.08.12.744375Cold Spring Harbor Laboratory2026-08-17
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Protein design to broadly reprogram engineered T cell function
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https://www.biorxiv.org/content/10.64898/2026.08.13.742806v1?rss=1
2026-08-17doi:10.64898/2026.08.13.742806Cold Spring Harbor Laboratory2026-08-17
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Compact Oligomerized-Motif Promoters for Adjustable Control of Transcription (COMPACT) for Robust, Tunable and Bidirectional Gene Expression in Mammalian Cells
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https://www.biorxiv.org/content/10.64898/2026.08.17.745230v1?rss=1
2026-08-19doi:10.64898/2026.08.17.745230Cold Spring Harbor Laboratory2026-08-19
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TRACER navigates rearrangement-driven sesterterpene chemical space via multimodal enzyme-product representation learning
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https://www.biorxiv.org/content/10.64898/2026.08.16.745124v1?rss=1
2026-08-19doi:10.64898/2026.08.16.745124Cold Spring Harbor Laboratory2026-08-19
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ProtoNetStack for DNA-Encoded Source Routing and Majority Aggregation in Protocell Molecular Nanonetworks
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https://www.biorxiv.org/content/10.64898/2026.08.14.744843v1?rss=1
2026-08-20doi:10.64898/2026.08.14.744843Cold Spring Harbor Laboratory2026-08-20
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Efficient exploration of sequence space enables rapid generation of functional genome editors
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https://www.biorxiv.org/content/10.64898/2026.08.16.745112v1?rss=1
2026-08-20doi:10.64898/2026.08.16.745112Cold Spring Harbor Laboratory2026-08-20
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Expanding the catabolic capacity of Pseudomonas putida to acetovanillone, 5-carboxyvanillate, and vanillyl glyoxylate for muconate production from kraft lignin-derived aromatics
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https://www.biorxiv.org/content/10.64898/2026.08.18.745639v1?rss=1
2026-08-20doi:10.64898/2026.08.18.745639Cold Spring Harbor Laboratory2026-08-20
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Molecular communication enables cooperative genomic RNA replication in all-aqueous droplet colonies
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https://www.biorxiv.org/content/10.64898/2026.08.15.744999v1?rss=1
2026-08-20doi:10.64898/2026.08.15.744999Cold Spring Harbor Laboratory2026-08-20
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Disruption of sRNA Function Using Synthetic Arginine Rich Motif Peptides
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https://www.biorxiv.org/content/10.64898/2026.08.19.745773v1?rss=1
2026-08-20doi:10.64898/2026.08.19.745773Cold Spring Harbor Laboratory2026-08-20
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Cell-Based Sensor for Extracellular DNA
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https://www.biorxiv.org/content/10.64898/2026.08.19.745795v1?rss=1
2026-08-20doi:10.64898/2026.08.19.745795Cold Spring Harbor Laboratory2026-08-20
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Virus-like particle-delivered base editor collection to expand the genome engineering toolbox
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https://www.biorxiv.org/content/10.64898/2026.08.17.745336v1?rss=1
2026-08-21doi:10.64898/2026.08.17.745336Cold Spring Harbor Laboratory2026-08-21
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Adaptive laboratory evolution rewires Pseudomonas putida for resource-efficient acetate assimilation
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https://www.biorxiv.org/content/10.64898/2026.08.20.746122v1?rss=1
2026-08-21doi:10.64898/2026.08.20.746122Cold Spring Harbor Laboratory2026-08-21
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Glycine detection with a nuclease-stable L-RNA sensor
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https://www.biorxiv.org/content/10.64898/2026.08.18.745542v1?rss=1
2026-08-21doi:10.64898/2026.08.18.745542Cold Spring Harbor Laboratory2026-08-21
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Engineering growth-coupled metabolic biosensors for disease prognosis and diagnosis using full growth trajectories
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https://www.biorxiv.org/content/10.64898/2026.08.04.740108v1?rss=1
2026-08-12doi:10.64898/2026.08.04.740108Cold Spring Harbor Laboratory2026-08-12
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A synthetic biology approach to bacterial transcription initiation: RNA aptamer based in vitro transcription assay for rapidly testing bacterial RNA polymerases, promoters and inhibitors.
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https://www.biorxiv.org/content/10.64898/2026.08.11.744185v1?rss=1
View larger version (42K):
org.highwire.dtl.DTLVardef@1632360org.highwire.dtl.DTLVardef@1a77977org.highwire.dtl.DTLVardef@1780c9org.highwire.dtl.DTLVardef@1082e05_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>2026-08-12doi:10.64898/2026.08.11.744185Cold Spring Harbor Laboratory2026-08-12