bioRxiv Subject Collection: Immunology
https://biorxiv.org
This feed contains articles for bioRxiv Subject Collection "Immunology"
bioRxivbioRxivhttps://www.biorxiv.org/sites/default/files/bioRxiv_article.jpg
https://www.biorxiv.org
<![CDATA[
Trans-presentation of IL-15 by IL15Rα attenuates tumor immune surveillance and is dispensable for IL-15-dependent tumor growth control
]]>
https://www.biorxiv.org/content/10.64898/2026.06.30.732683v1?rss=1
2026-07-03doi:10.64898/2026.06.30.732683Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Single-cell analysis of an adult IBD INCEPTION cohort reveals Galectin-linked disease mechanisms
]]>
https://www.biorxiv.org/content/10.64898/2026.06.30.735473v1?rss=1
2026-07-03doi:10.64898/2026.06.30.735473Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Vitamin D mitigates Inflammatory Bone Loss in Postmenopausal Osteoporosis via modulating the Gut-Immune-Bone axis
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735433v1?rss=1
2026-07-03doi:10.64898/2026.06.29.735433Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Characterization of the IGH locus and tissue specific immunoglobulin repertoires in turbot (Scophthalmus maximus).
]]>
https://www.biorxiv.org/content/10.64898/2026.06.30.735498v1?rss=1
2026-07-03doi:10.64898/2026.06.30.735498Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
A Metabolic Enzyme, Pyruvate Carboxylase, Functions as a Sequence-Selective Small RNA Sensor for Antiviral Immunity
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735367v1?rss=1
2026-07-03doi:10.64898/2026.06.29.735367Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Dual Th1 and tissue-repair Treg cells accumulate in skeletal muscle preserving tissue integrity during infection
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.734788v1?rss=1
2026-07-03doi:10.64898/2026.06.29.734788Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
A Co-culture Cell-Based Reporter Assay for Quantitative Measurement of Integrin αvβ8-Mediated Activation of Latent TGF-β1
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735300v1?rss=1
2026-07-03doi:10.64898/2026.06.29.735300Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Selection of potent biologic antagonists of the cannabinoid GPCR CB2R from a constrained peptide library
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735442v1?rss=1
2026-07-03doi:10.64898/2026.06.29.735442Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Gingipain-containing products from Porphyromonas gingivalis promote epithelial CCL20 signaling and γδ T-cell accumulation in COPD-like airways
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.734663v1?rss=1
2026-07-03doi:10.64898/2026.06.29.734663Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Preserved Barrier Integrity and Altered Immune Profiles in Chronic Cannabis Users: Potential Roles of Δ9-Tetrahydrocannabinol
]]>
https://www.biorxiv.org/content/10.64898/2026.07.02.736074v1?rss=1
2026-07-03doi:10.64898/2026.07.02.736074Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Analysis of genetic variation in the bovine Mannose Receptor gene (MRC1), its influence on receptor expression, and a potential association with resistance to bovine tuberculosis
]]>
https://www.biorxiv.org/content/10.64898/2026.06.27.734952v1?rss=1
A; Ser988Asn) in C-type lectin-like domain (CTLD) 6, most prevalent in Sahiwal cattle. Structural modelling suggested that the S988N substitution, which is spatially separated from the monosaccharide binding site of CTLD4, might indirectly affect glycan binding, perhaps through a conformational change in the receptor. Monocyte-derived macrophages upregulated MR expression during differentiation, with heterozygous (G/A) animals showing higher MR expression and increased uptake of GFP-M. bovis BCG, although differences were not statistically significant. Anti-CD206 blockade did not inhibit BCG internalization, either indicating that this specific antibody did not bind to a CTLD involved in ligand binding or that MR is not the sole entry receptor. These results highlight naturally occurring MRC1 polymorphisms that may influence MR structure and macrophage function, providing a foundation for future studies to assess their role in bTB susceptibility.
]]>2026-07-03doi:10.64898/2026.06.27.734952Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
DPP9-mediated inflammasome repression protects against checkpoint inhibitor lung toxicity
]]>
https://www.biorxiv.org/content/10.64898/2026.06.30.735609v1?rss=1
2026-07-03doi:10.64898/2026.06.30.735609Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
Mapping the immune landscape in small cell lung cancer unveils a distinct tumor-reactive CD8+ T cell molecular signature
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735200v1?rss=1
2026-07-03doi:10.64898/2026.06.29.735200Cold Spring Harbor Laboratory2026-07-03
<![CDATA[
The lack of macrophage fragment adhesion is a benchmark of dormant hematopoietic stem cells throughout the lifespan
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735148v1?rss=1
2026-07-02doi:10.64898/2026.06.29.735148Cold Spring Harbor Laboratory2026-07-02
<![CDATA[
Synovitis in systemic sclerosis is an interferon-driven stromal condition distinct from rheumatoid arthritis
]]>
https://www.biorxiv.org/content/10.64898/2026.06.30.733140v1?rss=1
View larger version (41K):
org.highwire.dtl.DTLVardef@59b9f0org.highwire.dtl.DTLVardef@be5b8aorg.highwire.dtl.DTLVardef@16bfce6org.highwire.dtl.DTLVardef@a8a05e_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>2026-07-02doi:10.64898/2026.06.30.733140Cold Spring Harbor Laboratory2026-07-02
<![CDATA[
Wobble Vaccines: Cross-Strain Protection Through Epitope Hierarchy Manipulation
]]>
https://www.biorxiv.org/content/10.64898/2026.07.01.735277v1?rss=1
2026-07-01doi:10.64898/2026.07.01.735277Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Targeted depletion of CD38+ autoreactive T cells prevents type 1 diabetes
]]>
https://www.biorxiv.org/content/10.64898/2026.06.27.734105v1?rss=1
2026-07-01doi:10.64898/2026.06.27.734105Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Neutrophil Extracellular Trap Formation and Complement Activation Pathways Dominate Microbiota-dependent disease bias in lupus-prone female NZM2328 mice
]]>
https://www.biorxiv.org/content/10.64898/2026.06.28.735075v1?rss=1
2026-07-01doi:10.64898/2026.06.28.735075Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Uncertainty-aware quantitative analysis of the structure and dynamics of T cell receptor repertoires
]]>
https://www.biorxiv.org/content/10.64898/2026.06.28.735097v1?rss=1
2026-07-01doi:10.64898/2026.06.28.735097Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Schistosoma mansoni Granulin binds the human neutrophil receptor CD177 and modulates neutrophil activation
]]>
https://www.biorxiv.org/content/10.64898/2026.06.27.734962v1?rss=1
2026-07-01doi:10.64898/2026.06.27.734962Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Thymic Treg-derived T follicular regulatory cells prevent catastrophic humoral autoimmunity in response to TLR7-driven inflammation
]]>
https://www.biorxiv.org/content/10.64898/2026.06.28.735092v1?rss=1
2026-07-01doi:10.64898/2026.06.28.735092Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
B cell-intrinsic IRF8 transcriptionally reprograms antigen presentation to sustain CD8⁺ T cell antitumor immunity
]]>
https://www.biorxiv.org/content/10.64898/2026.06.28.735129v1?rss=1
2026-07-01doi:10.64898/2026.06.28.735129Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Antibody Correlates of Resilience to Staphylococcus aureus Disease and Recurrence in Children
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734609v1?rss=1
2026-07-01doi:10.64898/2026.06.26.734609Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Cryo-EM reveals alternative modes of dimerization driving activation of IKK
]]>
https://www.biorxiv.org/content/10.64898/2026.06.29.735262v1?rss=1
2026-07-01doi:10.64898/2026.06.29.735262Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Mitochondrial STAT3-mediated suppression of apoptosis constrains antimycobacterial immunity
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734825v1?rss=1
2026-07-01doi:10.64898/2026.06.26.734825Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Disruption of a CCR5-like immunoglobulin gene is linked to plague susceptibility in black-footed ferrets
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734856v1?rss=1
View larger version (60K):
org.highwire.dtl.DTLVardef@ae4a80org.highwire.dtl.DTLVardef@9d19d9org.highwire.dtl.DTLVardef@c0f84org.highwire.dtl.DTLVardef@1ced879_HPS_FORMAT_FIGEXP M_FIG C_FIG
]]>2026-07-01doi:10.64898/2026.06.26.734856Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Sequential infection reprograms the immune landscape to shape future responses
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734836v1?rss=1
2026-07-01doi:10.64898/2026.06.26.734836Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
CD56dimCD16dim NK cells are the dominant effector cells against HIV-infected primary T-cells
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734820v1?rss=1
2026-07-01doi:10.64898/2026.06.26.734820Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
Viral capsid delivery of cGAMP enhances STING-dependent antitumor immune response
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.734859v1?rss=1
2026-07-01doi:10.64898/2026.06.26.734859Cold Spring Harbor Laboratory2026-07-01
<![CDATA[
ARL15 promotes inflammatory fibroblast activation and disease severity in rheumatoid arthritis: integrated transcriptomic and collagen-induced arthritis model analyses
]]>
https://www.biorxiv.org/content/10.64898/2026.06.26.733622v1?rss=1
2026-07-01doi:10.64898/2026.06.26.733622Cold Spring Harbor Laboratory2026-07-01