bioRxiv Subject Collection: Biochemistry
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This feed contains articles for bioRxiv Subject Collection "Biochemistry"
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The Z-shaped N-terminal Domain of Atg11 Coordinates Atg9 Recruitment in Selective Autophagy
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https://www.biorxiv.org/content/10.64898/2026.08.17.744853v1?rss=1
2026-08-19doi:10.64898/2026.08.17.744853Cold Spring Harbor Laboratory2026-08-19
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Architectures and biochemical activities of Mtl1-Red1 MTREC helicase complexes
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https://www.biorxiv.org/content/10.64898/2026.08.18.745603v1?rss=1
2026-08-19doi:10.64898/2026.08.18.745603Cold Spring Harbor Laboratory2026-08-19
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STEP-PTMs: Sequential TMT-based Enrichment and Profiling of Post-Translational Modifications
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https://www.biorxiv.org/content/10.64898/2026.08.18.745386v1?rss=1
2026-08-19doi:10.64898/2026.08.18.745386Cold Spring Harbor Laboratory2026-08-19
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Aegeline and Atorvastatin Synergistically Attenuate oxLDL-Induced Inflammation and Intracellular Cholesterol Accumulation in THP-1 Macrophages
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https://www.biorxiv.org/content/10.64898/2026.08.14.744794v1?rss=1
2026-08-18doi:10.64898/2026.08.14.744794Cold Spring Harbor Laboratory2026-08-18
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Membrane Mimetic-Thermal Proteome Profiling Reveals Broad, Sequence-Independent Membrane Protein Stabilization by Cholesteryl Hemisuccinate
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https://www.biorxiv.org/content/10.64898/2026.08.17.745344v1?rss=1
2026-08-18doi:10.64898/2026.08.17.745344Cold Spring Harbor Laboratory2026-08-18
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Phosphorylation alters the bulk chemical properties of Orc1 to tune DNA binding, phase separation, and heterochromatin partitioning.
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https://www.biorxiv.org/content/10.64898/2026.08.17.745304v1?rss=1
2026-08-18doi:10.64898/2026.08.17.745304Cold Spring Harbor Laboratory2026-08-18
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Chemical Interrogation and Reprogramming of ATAT1-Mediated Tubulin Acetylation
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https://www.biorxiv.org/content/10.64898/2026.08.17.745310v1?rss=1
2026-08-18doi:10.64898/2026.08.17.745310Cold Spring Harbor Laboratory2026-08-18
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A Scalable and Robust Workflow for Cost-Effective Post-Translational Modifications Profiling by Chemical Proteomics.
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https://www.biorxiv.org/content/10.64898/2026.08.17.745240v1?rss=1
2026-08-18doi:10.64898/2026.08.17.745240Cold Spring Harbor Laboratory2026-08-18
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Stereoselective Covalent Inhibitor of the Ovarian Cancer-Driving Transcription Factor PAX8
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https://www.biorxiv.org/content/10.64898/2026.08.15.745031v1?rss=1
2026-08-18doi:10.64898/2026.08.15.745031Cold Spring Harbor Laboratory2026-08-18
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Loss of PTPRB function remodels VEGFR1 activation in tumors overexpressing the receptor tyrosine kinase
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https://www.biorxiv.org/content/10.64898/2026.08.17.745152v1?rss=1
2026-08-17doi:10.64898/2026.08.17.745152Cold Spring Harbor Laboratory2026-08-17
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Fine tuning energy metabolism in skeletal muscle: Discovery of a novel autoinhibitory mechanism in the N-terminal extension of AMPKγ3
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https://www.biorxiv.org/content/10.64898/2026.08.16.744724v1?rss=1
2026-08-17doi:10.64898/2026.08.16.744724Cold Spring Harbor Laboratory2026-08-17
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Chemically programmed multistage morphogenesis in coacervate microdroplets
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https://www.biorxiv.org/content/10.64898/2026.08.16.745086v1?rss=1
2026-08-17doi:10.64898/2026.08.16.745086Cold Spring Harbor Laboratory2026-08-17
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Tensile Expansion Mass Spectrometry for single cell metabolomics imaging
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https://www.biorxiv.org/content/10.64898/2026.08.15.745024v1?rss=1
2026-08-17doi:10.64898/2026.08.15.745024Cold Spring Harbor Laboratory2026-08-17
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An On-Demand Nanodisc Platform for Reconstitution of Functional Membrane Proteins into Model and Living Membranes
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https://www.biorxiv.org/content/10.64898/2026.08.17.745191v1?rss=1
2026-08-17doi:10.64898/2026.08.17.745191Cold Spring Harbor Laboratory2026-08-17
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HMCES DNA-protein cross-links promote template slippage during DNA replication
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https://www.biorxiv.org/content/10.64898/2026.08.14.744967v1?rss=1
2026-08-17doi:10.64898/2026.08.14.744967Cold Spring Harbor Laboratory2026-08-17
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Presequences of non-imported mitochondrial proteins serve as quality control elements in the cytosol
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https://www.biorxiv.org/content/10.64898/2026.08.13.744608v1?rss=1
2026-08-17doi:10.64898/2026.08.13.744608Cold Spring Harbor Laboratory2026-08-17
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Comparison of the 4-helix bundle domains of perilipin 3 and perilipin 4 identifies features that contribute to lipid droplet binding
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https://www.biorxiv.org/content/10.64898/2026.08.15.745046v1?rss=1
2026-08-17doi:10.64898/2026.08.15.745046Cold Spring Harbor Laboratory2026-08-17
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Unusual photochemical characteristics of a novel BLUF-like protein from fungus
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https://www.biorxiv.org/content/10.64898/2026.08.14.744829v1?rss=1
2026-08-17doi:10.64898/2026.08.14.744829Cold Spring Harbor Laboratory2026-08-17
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Serum preprocessing workflows differentially shape biological readout in data-independent acquisition proteomics of systemic juvenile idiopathic arthritis
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https://www.biorxiv.org/content/10.64898/2026.08.15.745022v1?rss=1
2026-08-17doi:10.64898/2026.08.15.745022Cold Spring Harbor Laboratory2026-08-17
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Cryo-EM of a nucleotide-polymerizing ribozyme enables its predictive improvement
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https://www.biorxiv.org/content/10.64898/2026.08.14.744467v1?rss=1
2026-08-17doi:10.64898/2026.08.14.744467Cold Spring Harbor Laboratory2026-08-17
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Translesion synthesis protein ImuA from Mycolicibacterium smegmatis is a hexameric helicase-nuclease
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https://www.biorxiv.org/content/10.64898/2026.08.14.744951v1?rss=1
2026-08-17doi:10.64898/2026.08.14.744951Cold Spring Harbor Laboratory2026-08-17
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Production of membrane-embedded Bcl-2 proteins - Use of cell-free synthesis in continuous exchange for co-translational insertion of Bcl-2 proteins in lipid bilayer nanodiscs.
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https://www.biorxiv.org/content/10.64898/2026.08.15.745005v1?rss=1
View larger version (35K):
org.highwire.dtl.DTLVardef@b0ab12org.highwire.dtl.DTLVardef@af4becorg.highwire.dtl.DTLVardef@a17a7corg.highwire.dtl.DTLVardef@1706e7f_HPS_FORMAT_FIGEXP M_FIG C_FIG
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Structural basis of K<+>/H<+> antiport in YcgO and its inhibition by unphosphorylated PtsN
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https://www.biorxiv.org/content/10.64898/2026.08.14.744764v1?rss=1
2026-08-15doi:10.64898/2026.08.14.744764/H<+> antiport in YcgO and its inhibition by unphosphorylated PtsN]]>Cold Spring Harbor Laboratory2026-08-15
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Activity-based chemical proteomics uncovers unexpected covalent targetsof E64d and reveals a role for cysteine cathepsins in PLD3 proteostasis.
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https://www.biorxiv.org/content/10.64898/2026.08.14.744826v1?rss=1
2026-08-15doi:10.64898/2026.08.14.744826Cold Spring Harbor Laboratory2026-08-15
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Functional Differentiation of GH172 Arabinofuranosidases Through Divergent Quaternary Structures
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https://www.biorxiv.org/content/10.64898/2026.08.13.744632v1?rss=1
2026-08-15doi:10.64898/2026.08.13.744632Cold Spring Harbor Laboratory2026-08-15
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Location-dependent proteomics of the aorta reveal an atherosclerotic disease gradient shaped by hemodynamics
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https://www.biorxiv.org/content/10.64898/2026.08.13.744640v1?rss=1
2026-08-15doi:10.64898/2026.08.13.744640Cold Spring Harbor Laboratory2026-08-15
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Structural basis of end processing in the nucleosome by polynucleotide kinase phosphatase
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https://www.biorxiv.org/content/10.64898/2026.08.12.743989v1?rss=1
2026-08-13doi:10.64898/2026.08.12.743989Cold Spring Harbor Laboratory2026-08-13
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Conformational gating at histidine junctions coordinates proton translocation in respiratory complex I
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https://www.biorxiv.org/content/10.64898/2026.08.12.744383v1?rss=1
2026-08-13doi:10.64898/2026.08.12.744383Cold Spring Harbor Laboratory2026-08-13
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Reprogramming VHL with molecular glues enables selective degradation of caspase-2
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https://www.biorxiv.org/content/10.64898/2026.08.12.744529v1?rss=1
2026-08-13doi:10.64898/2026.08.12.744529Cold Spring Harbor Laboratory2026-08-13
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A detergent-free workflow for native membrane proteomics using Peptergents
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https://www.biorxiv.org/content/10.64898/2026.08.12.744532v1?rss=1
View larger version (56K):
org.highwire.dtl.DTLVardef@dd3307org.highwire.dtl.DTLVardef@412272org.highwire.dtl.DTLVardef@3c9fd7org.highwire.dtl.DTLVardef@21e287_HPS_FORMAT_FIGEXP M_FIG C_FIG HighlightsO_LIPeptergents preserve ligand-responsive membrane proteins.
C_LIO_LISupport chemoproteomics in thermal proteome profiling assays.
C_LIO_LISimplify membrane proteomics workflow.
C_LIO_LIMaintain native tissue-specific membrane biology.
C_LIO_LIPreserve fragile membrane protein assemblies.
C_LI
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