bioRxiv Subject Collection: All
https://biorxiv.org
This feed contains articles for bioRxiv Subject Collection "All"
bioRxivbioRxivhttps://www.biorxiv.org/sites/default/files/bioRxiv_article.jpg
https://www.biorxiv.org
<![CDATA[
Broadband gamma-band EEG changes during magnetophosphene perception induced by 20 Hz magnetic field stimulation
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718626v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718626Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Oncogenic Ras-Src-cortactin signaling rewires actin-generated forces to drive basement membrane rupture and initiate breast cancer invasion
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.717430v1?rss=1
2026-04-18doi:10.64898/2026.04.15.717430Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Calibration of in-frame indel variant effect predictors for clinical variant classification
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718599v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718599Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
LagCI Enables Inference of Temporal Causal Relationships from Dense Multi-Omic Time Series
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718654v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718654Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Unsupervised Machine Learning for Adaptive Immune Receptors with immuneML
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718648v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718648Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Improved deconvolution of circulating tumor DNA from ultra-low-pass whole-genome methylation sequencing using CelFiE-ISH
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718632v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718632Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Evolution and adaptations of the seminal proteome in an insect with traumatic insemination
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718635v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718635Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Crosstalk Between Calcium Dynamics and ROS Levels in U87 Glioblastoma Cells Exposed to Extremely Low Frequency Pulsed Electromagnetic Fields
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718611v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718611Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Efficacy of Purified Borrelial Lipoproteins (PBL) as an oral formulation in reducing transmission of Lyme spirochetes from reservoir hosts to Ixodes scapularis ticks
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718640v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718640Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Whole-fingertip 3D Skin Surface Deformation under Tangential Loading
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718652v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718652Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
The Signal Generating (SiGn) fMRI Phantom
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.717370v1?rss=1
2026-04-18doi:10.64898/2026.04.15.717370Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Pan-cancer survival modeling reveals structural limits of genomic feature integration in immunotherapy outcomes
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718634v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718634Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Effects of artificial light colour, intensity, structure and contrast on moth flight behaviour
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718644v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718644Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Dissecting polycomb complexes for enhanced fetal hemoglobin production
]]>
https://www.biorxiv.org/content/10.64898/2026.04.16.718974v1?rss=1
2026-04-18doi:10.64898/2026.04.16.718974Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Therapy-associated mutagenesis at CTCF binding sites is shaped by chromatin context and DNA repair capacity
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718780v1?rss=1
2026-04-18doi:10.64898/2026.04.15.718780Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
Phosphoregulated SMCR8-FIP200 interaction connects the ALS/FTD-linked C9orf72 complex to autophagy initiation and mitochondrial quality control
]]>
https://www.biorxiv.org/content/10.64898/2026.04.16.718395v1?rss=1
2026-04-18doi:10.64898/2026.04.16.718395Cold Spring Harbor Laboratory2026-04-18
<![CDATA[
β-Amyloid and Glutathione Dysregulation Cooperatively Drive Lipid Peroxidation and Ferroptosis in Neuron-Like Cells
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718809v1?rss=1
2026-04-17doi:10.64898/2026.04.15.718809Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Predicting children's literacy from task-based fMRI: Neural heterogeneity and task-dependent performance
]]>
https://www.biorxiv.org/content/10.64898/2026.04.17.719130v1?rss=1
Learn > Localizer = CharProc, and for Verbal with PhonLex = Learn > Localizer = CharProc. Simple contrasts generally outperformed subtractive contrasts in predicting behavioral scores. Key neural predictors, identified through whole-brain and region-of-interest analyses, included the left inferior frontal gyrus, supramarginal gyrus, ventral occipitotemporal cortex, insula, and default mode network regions. Together, these findings indicate that, for predicting literacy traits in children, active tasks and tasks that engage brain systems involved in multisensory learning tend to outperform both passive paradigms and simple subtractive task contrasts. This study provides a methodological benchmark for brain-based prediction of reading ability and highlights the value of activation heterogeneity across distributed regions as a potential marker for tracking literacy development over time.
]]>2026-04-17doi:10.64898/2026.04.17.719130Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Rewiring the Human Brain: On the Fabric of Associative Thinking
]]>
https://www.biorxiv.org/content/10.64898/2026.04.17.718886v1?rss=1
2026-04-17doi:10.64898/2026.04.17.718886Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Hippocampus consolidates memory in the upstate of cortical sleep slow oscillations
]]>
https://www.biorxiv.org/content/10.64898/2026.04.17.719155v1?rss=1
2026-04-17doi:10.64898/2026.04.17.719155Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Genome-wide genealogies reveal deep admixtures forming modern humans
]]>
https://www.biorxiv.org/content/10.64898/2026.04.17.719197v1?rss=1
2026-04-17doi:10.64898/2026.04.17.719197Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
APOBEC3 antagonism fully explains HIV-1 Vif essentiality under interferon and differentiation conditions
]]>
https://www.biorxiv.org/content/10.64898/2026.04.16.719124v1?rss=1
2026-04-17doi:10.64898/2026.04.16.719124Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Convergent antigenic drift of the influenza hemagglutinin lateral patch across time and species
]]>
https://www.biorxiv.org/content/10.64898/2026.04.16.718966v1?rss=1
2026-04-17doi:10.64898/2026.04.16.718966Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
155 years after Van Beneden: redescription and first molecular characterisation of the enigmatic type species, Ascarophis morrhuae Van Beneden, 1870 (Nematoda, Cystidicolidae), and comparison to other Ascarophis species in the North Atlantic
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718624v1?rss=1
2026-04-17doi:10.64898/2026.04.15.718624Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
GANGE: Achieving Sequencing Without Sequencing With Diffusion Guided Generative Genomic Transformer
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718133v1?rss=1
92% accuracy consistently. This all makes it possible to drastically pull down sequencing project cost. GANGE was tested across A. thaliana, O. sativa genomes and Human chromosome 1 where it delivered outstanding assembly performance. Besides this, it was also used to accurately generate 2kb upstream promoters of all the genes from 12 different species, demonstrating that one can now also take up regulomics research just using RNA data alone when genome sequence is not available. With this all, GANGE brings a democratic turning point in the area of genomics and sequencing research.
]]>2026-04-17doi:10.64898/2026.04.15.718133Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
cellNexus: Quality control, annotation, aggregation and analytical layers for the Human Cell Atlas data
]]>
https://www.biorxiv.org/content/10.64898/2026.04.14.718336v1?rss=1
2026-04-17doi:10.64898/2026.04.14.718336Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Bacteria-mimetic bioadhesives with multivalent mucoadhesion and drug-compatible delivery
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718429v1?rss=1
400 J/m^2 without forming covalent bonds to tissue. Confocal imaging reveals deep tissue penetration (~80 m) with markedly enhanced mucin binding and no loss of cytocompatibility. Ex vivo intestinal delivery and in vitro drug release tests demonstrate improved drug transport and tissue exposure compared to carbodiimide-mediated covalent bonding strategy. These findings establish a bacteria-mimetic bioadhesion strategy for tissue repair and drug delivery. Novelty Statement: Bioadhesive designs have drawn inspiration from nature such as mussel-inspired catechol chemistry and gecko-inspired dry adhesion. In contrast, bacterial adhesion mechanisms, despite enabling robust colonization of mucus-lined tissues under demanding conditions, remain largely overlooked. This work introduces a bacteria-mimetic bioadhesion strategy that selectively repurposes a short, non-pathogenic peptide derived from a Vibrio cholerae adhesin to enhance bioadhesion through multivalent, cooperative physical interactions rather than covalent bonding. This strategy significantly toughens adhesion even on chitosan, a polymer already rich in adhesive functional groups. By decoupling bacterial adhesion function from pathogenic risk, this study establishes bacterial adhesion peptides as a safe, modular, and mechanistically distinct foundation for next generation bioadhesives with improved drug compatibility.
]]>2026-04-17doi:10.64898/2026.04.15.718429Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
ARMH3 acts as a central scaffold at the Golgi/TGN through interactions with Arl5, GBF1, and PI4KB
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718671v1?rss=1
2026-04-17doi:10.64898/2026.04.15.718671Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
Dorsal fins are not universal stabilizers in cetaceans: limited yaw effects and flipper-coupled roll stability
]]>
https://www.biorxiv.org/content/10.64898/2026.04.15.718588v1?rss=1
2026-04-17doi:10.64898/2026.04.15.718588Cold Spring Harbor Laboratory2026-04-17
<![CDATA[
PREFERENTIAL INVASION OF DIFFERENTIATED BLADDER CARCINOMA CELLS BY FLAGELLATED GROUP B2 ESCHERICHIA COLI
]]>
https://www.biorxiv.org/content/10.64898/2026.04.16.718932v1?rss=1
2026-04-17doi:10.64898/2026.04.16.718932Cold Spring Harbor Laboratory2026-04-17